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heart_n right_a vein_n ventricle_n 3,268 5 13.1569 5 true
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A41730 De succo pancreatico, or, A physical and anatomical treatise of the nature and office of the pancreatick juice shewing its generation in the body, what diseases arise by its vitiation : from whence in particular, by plain and familiar examples, is accurately demonstrated, the causes and cures of agues, or intermitting feavers, hitherto so difficult and uncertain, with sundry other things of worthy note / written by D. Reg. de Graaf ... ; and translated by Christopher Pack ...; Tractatus anatomico-medicus de succi pancreatici natura & usu. English Graaf, Reinier de, 1641-1673.; Packe, Christopher, fl. 1670-1711. 1676 (1676) Wing G1463; ESTC R17762 82,340 198

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membrane_n their_o substance_n differ_v not_o only_o among_o themselves_o by_o way_n of_o connexion_n as_o they_o be_v conglobate_v and_o conglomerate_v but_o also_o in_o the_o peculiar_a vessel_n for_o the_o conglobated_a be_v give_v to_o the_o lymphatic_a vessel_n which_o towards_o and_o at_o the_o common_a ductus_fw-la thoracicus_n or_o the_o superior_a fold_v thereof_o especial_o conspicuous_a in_o dog_n drive_v out_o a_o liquor_n prepare_v in_o themselves_o or_o receive_v from_o another_o but_o the_o conglomerate_v dispose_v their_o liquor_n into_o peculiar_a cavity_n as_o the_o salivales_fw-la into_o the_o mouth_n the_o pancreas_n into_o the_o duodenum_fw-la and_o so_o of_o other_o that_o the_o motion_n of_o the_o lympha_fw-la be_v such_o as_o we_o have_v even_o now_o assert_v and_o not_o from_o the_o centre_n to_o the_o circumference_n be_v prove_v by_o the_o value_v in_o the_o lymphatic_a vessel_n everywhere_o exist_v as_o may_v be_v see_v in_o a_o little_a treatise_n concern_v the_o value_v of_o the_o lymphatic_a vessel_n by_o the_o most_o famous_a and_o our_o entire_a friend_n dr._n raysch_n anatomyst_fw-mi of_o amsterdam_n print_v anno_fw-la 1665._o by_o who_o indefatigable_a diligence_n at_o the_o same_o time_n be_v discover_v that_o vessel_n which_o he_o call_v the_o bronchial_a artery_n by_o reason_n that_o it_o accompani_v the_o widening_n of_o the_o branch_n of_o the_o sharp_a artery_n through_o the_o whole_a substance_n of_o the_o lung_n as_o may_v be_v see_v by_o the_o figure_n thereof_o insert_v into_o his_o little_a book_n aforemention_v and_o worthy_o communicate_v to_o we_o see_v that_o the_o duct'_v and_o also_o the_o substance_n of_o the_o glandule_n be_v diverse_a it_o be_v worthy_a our_o enquiry_n whether_o the_o humour_n observe_v in_o all_o the_o glandule_n be_v of_o the_o same_o or_o a_o different_a quality_n but_o we_o shall_v answer_v that_o the_o same_o or_o like_o humour_n be_v separate_v in_o all_o the_o glandule_n of_o a_o diverse_a species_n for_o one_o liquor_n be_v depose_v in_o the_o conglobated_a and_o another_o in_o the_o conglomerated_a for_o that_o which_o be_v separate_v in_o the_o conglobated_a be_v all_o of_o the_o same_o nature_n which_o be_v prove_v not_o only_o by_o the_o substance_n of_o the_o same_o glandule_n every_o where_o consimilar_v but_o also_o by_o the_o way_n by_o which_o they_o be_v all_o distburdened_a for_o as_o much_o as_o further_o appear_v to_o we_o end_v in_o the_o ductus_fw-la thoracicus_n moreover_o it_o be_v further_a demonstrable_a by_o the_o liquor_n of_o the_o conglobated_a glandule_n ordinary_o find_v more_o saltish_a and_o less_o acid_n in_o they_o than_o in_o the_o conglomerated_a glandule_n of_o the_o pancreas_n nevertheless_o more_o of_o acidity_n and_o salsitude_n than_o that_o of_o the_o conglomerate_v salivales_fw-la from_o whence_o it_o be_v manifest_a that_o a_o liquor_n be_v separate_v from_o the_o conglomerated_a glandule_n of_o the_o salivales_fw-la and_o pancreas_n not_o alike_o in_o all_o its_o quality_n as_o we_o have_v assert_v even_o now_o to_o be_v do_v in_o the_o conglobated_a in_o which_o matter_n that_o we_o may_v be_v more_o certain_a at_o the_o same_o time_n and_o to_o the_o same_o animal_n we_o apply_v the_o instrument_n depict_v tab._n ii_o fig._n ii_o both_o to_o the_o ductus_fw-la pancreaticus_fw-la and_o to_o the_o upper_a salivary_n dust_n as_o be_v exhibit_v tab._n iii_o fig._n ii_o but_o we_o find_v a_o notable_a diversity_n of_o the_o aforesaid_a liquor_n for_o the_o salival_n be_v either_o temperate_a or_o insipid_a but_o the_o succus_fw-la pancreaticus_fw-la be_v acid_o salt_n or_o such_o like_a for_o the_o most_o part_n as_o we_o have_v describe_v it_o in_o the_o former_a chapter_n see_v there_o be_v a_o diverse_a juice_n of_o diverse_a glandule_n it_o deserve_v our_o enquiry_n what_o use_v every_o one_o may_v have_v and_o whether_o it_o be_v prositable_a or_o unnecessary_a that_o be_v whether_o it_o bring_v any_o 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blood_n so_o that_o according_a to_o the_o order_n of_o nature_n they_o may_v not_o any_o more_o be_v commix_v therewith_o but_o be_v whole_o separate_v from_o the_o body_n which_o be_v clear_o see_v in_o the_o urine_n the_o which_o be_v separate_v from_o the_o mass_n of_o blood_n in_o the_o rein_n and_o thence_o deduce_v through_o the_o ureter_n into_o the_o bladder_n from_o whence_o after_o some_o stay_n according_a to_o the_o dictate_v of_o the_o will_n by_o the_o urinary_a passage_n it_o be_v exclude_v from_o the_o body_n so_o that_o it_o can_v never_o again_o return_v so_o the_o juice_n of_o the_o conglomerated_a glandule_n be_v effuse_v through_o particular_a duct_n into_o divers_a cavity_n of_o the_o body_n where_o it_o may_v be_v mingle_v with_o other_o humour_n necessary_a for_o nourishment_n and_o be_v least_o of_o all_o to_o be_v esteem_v for_o excrementitious_a or_o unprofitable_a which_o that_o it_o may_v likewise_o be_v make_v know_v in_o like_a manner_n as_o we_o have_v prosecute_v the_o liquor_n of_o the_o conglobated_a glandule_n so_o also_o we_o shall_v follow_v that_o of_o the_o conglomerated_a flow_v from_o the_o salivales_fw-la and_o the_o pancreas_n the_o hospital_n be_v separate_v from_o the_o blood_n in_o the_o maxillary_a glandule_n as_o well_o the_o superior_a as_o the_o inferior_a and_o be_v carry_v by_o the_o say_a salival_n duct_n into_o the_o cavity_n of_o the_o mouth_n where_o it_o may_v be_v mix_v with_o the_o assume_v aliment_n or_o out_o of_o the_o time_n of_o the_o aliment_n assumption_n be_v continual_o swallow_v the_o which_o we_o never_o better_a consider_v than_o whilst_o we_o hold_v something_o in_o our_o mouth_n the_o which_o because_o of_o the_o cleanness_n of_o the_o place_n in_o which_o we_o be_v we_o will_v not_o spit_v out_o neither_o dare_v we_o swallow_v it_o down_o for_o the_o mouth_n be_v very_o quick_o fill_v with_o hospital_n therefore_o the_o hospital_n although_o without_o our_o knowledge_n be_v continual_o 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where_o the_o chyle_n begin_v in_o the_o stomach_n aught_o to_o be_v perfect_v
he_o declare_v that_o aqua_fw-la mulsa_fw-la or_o hydromel_n or_o if_o to_o cleanse_v more_o powerful_o with_o the_o decoction_n or_o bitter_a juice_n beforementioned_a of_o wormwood_n centaury_n or_o lupin_n that_o may_v be_v effect_v add_v honey_n or_o gall_n which_o above_o all_o other_o thing_n as_o have_v be_v often_o say_v do_v make_v those_o thing_n which_o be_v viscous_a fluid_a etc._n etc._n but_o the_o succus_fw-la pancreaticus_fw-la be_v pregnant_a with_o a_o subacid_a spirit_n as_o appear_v by_o the_o precedent_n reason_n and_o experiment_n do_v in_o like_a manner_n augment_v the_o viscidity_n of_o the_o aliment_n by_o the_o solution_n of_o their_o fluidity_n the_o which_o be_v so_o as_o it_o be_v more_o than_o sufficient_o know_v we_o will_v not_o delay_v time_n by_o further_a proof_n concern_v the_o manner_n whereby_o acid_n in_o the_o thin_a gut_n do_v return_n to_o a_o liquid_a and_o fluxile_n motion_n or_o otherwise_o to_o a_o ine●t_n and_o pituitous_a viscidity_n we_o shall_v only_o say_v that_o in_o our_o judgement_n it_o so_o happen_v for_o as_o much_o as_o by_o the_o tenuity_n and_o sharpness_n of_o the_o part_n stir_v up_o by_o the_o effervescency_n the_o phlegm_n be_v thereby_o as_o with_o sword_n incide_v and_o attenuate_v into_o very_a minute_n part_n that_o which_o attain_v a_o whitish_a colour_n then_o observable_a in_o the_o more_o fluid_a part_n of_o the_o aliment_n we_o think_v it_o deducible_a from_o the_o acidity_n of_o the_o pancreatic_a juice_n because_o we_o may_v note_v that_o many_o other_o thing_n abound_v with_o a_o lixivious_a salt_n and_o oil_n do_v wax_n white_a upon_o the_o affusion_n of_o acid_n so_o that_o vinegar_n or_o sharp_a wine_n be_v pour_v upon_o common_a sulphur_n dissolve_v with_o any_o lixivium_n and_o grow_v red_a that_o reddish_n colour_n be_v so_o change_v that_o it_o be_v make_v almost_o like_a to_o milk_n wherefore_o also_o it_o be_v call_v by_o the_o chemist_n lac_n sulphuris_fw-la the_o same_o be_v apparent_a in_o the_o resinious_a extract_n of_o vegetables_n as_o also_o in_o spirit_n of_o heart_n horn_n or_o soot_n be_v replete_a with_o much_o volatile_a salt_n with_o which_o a_o acid_n spirit_n be_v mix_v acquire_v a_o milky_a colour_n all_o those_o thing_n be_v right_o consider_v we_o judge_v second_o that_o the_o effervescency_n in_o the_o thin_a gut_n be_v exceed_o necessary_a for_o the_o right_a separation_n of_o the_o profitable_a part_n from_o the_o unprofitable_a but_o perhaps_o some_o who_o be_v altogether_o wed_v to_o antiquity_n admit_v nothing_o which_o to_o they_o be_v novel_a because_o they_o have_v read_v or_o understand_v nothing_o in_o the_o ancient_n concern_v this_o our_o expect_a secretion_n by_o fermentation_n will_v not_o think_v that_o such_o a_o preparation_n be_v require_v to_o separate_v the_o profitable_a part_n of_o the_o aliment_n from_o the_o unprofitable_a but_o that_o the_o alteration_n which_o be_v perform_v in_o the_o stomach_n be_v sufficient_a 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bodily_a eye_n that_o the_o spirit_n by_o the_o same_o reason_n be_v diffuse_v through_o the_o pore_n of_o the_o body_n nevertheless_o after_o a_o manner_n we_o understand_v it_o with_o the_o eye_n of_o our_o mind_n whilst_o we_o see_v a_o stupendous_a virtue_n in_o some_o medicament_n external_o apply_v the_o same_o thing_n be_v often_o observe_v by_o anatomist_n when_o after_o the_o incision_n of_o the_o peritonaeum_fw-la they_o receive_v the_o foetid_v flatulency_n pass_v through_o the_o tunicle_n of_o the_o gut_n to_o the_o nostril_n but_o because_o the_o spirituous_a and_o volatile_a part_n be_v not_o sufficient_a to_o sustain_v life_n but_o moreover_o acid_n oleous_a and_o salt_n part_n be_v also_o require_v therefore_o there_o be_v need_n of_o a_o new_a alteration_n of_o thing_n assume_v that_o those_o part_n by_o a_o decent_a copiousness_n may_v be_v separate_v from_o the_o superfluous_a and_o unprofitable_a which_o alteration_n we_o call_v effervescency_n and_o by_o help_n of_o which_o we_o judge_v with_o our_o sometime_o famous_a professor_n francis_n de_fw-fr le_fw-fr boe-sylvius_n from_o who_o lecture_n as_o well_o public_a as_o private_a we_o do_v not_o deny_v to_o have_v draw_v many_o fundamental_o of_o this_o doctrine_n that_o secretion_n to_o be_v accomplish_v we_o do_v not_o only_o judge_v by_o that_o effervescency_n mediate_v the_o more_o subtle_a and_o fluid_a part_n of_o aliment_n but_o also_o the_o pituity_n by_o the_o help_n thereof_o dissolve_v in_o the_o thin_a gut_n part_n of_o which_o be_v carry_v together_o with_o the_o better_a portion_n of_o the_o bile_n and_o succus_fw-la pancreaticus_fw-la through_o the_o vermiculous_a crust_n of_o the_o intestine_n into_o the_o milky_a vein_n from_o hence_o to_o the_o cistern_n or_o common_a receptacle_n of_o the_o chyle_n and_o lympha_fw-la place_v in_o the_o region_n of_o the_o loin_n under_o the_o appendix_n of_o the_o diaphragma_n and_o from_o thence_o ascend_v through_o the_o chyliferus_n or_o more_o right_o the_o lymphatic_a ductus_fw-la thoracicus_n because_o it_o continual_o carry_v the_o lympha_fw-la and_o the_o chyle_n only_o by_o interval_n to_o the_o subclavian_n or_o leave_v jugular_a vein_n that_o from_o thence_o it_o may_v descend_v with_o the_o blood_n through_o the_o superior_a trunk_n of_o the_o vena_fw-la cava_fw-la descend_v into_o the_o right_a ear_n of_o the_o heart_n and_o the_o right_a ventricle_n thereof_o and_o in_o the_o right_a ear_n and_o right_a ventricle_n of_o the_o heart_n it_o be_v confuse_v both_o with_o the_o ascend_n and_o descend_v blood_n and_o also_o impregnate_v with_o the_o pancreatic_a juice_n the_o bile_n phlegm_n and_o lympha_fw-la from_o whence_o it_o acquire_v a_o requisite_a consistency_n of_o blood_n this_o confirm_v what_o we_o have_v say_v that_o any_o thing_n acid_n coagulate_v all_o fatness_n and_o oil_n but_o because_o on_o the_o other_o side_n the_o aforesaid_a humour_n have_v in_o themselves_o a_o force_n of_o attemper_v we_o need_v not_o fear_v too_o great_a a_o consistency_n of_o the_o blood_n
they_o call_v stuypiens_n dutch._n do_v proceed_v from_o the_o say_v more_o acid_n pancreatic_a juice_n who_o have_v accurate_o attend_v to_o those_o invasion_n and_o the_o symptom_n accompany_v they_o and_o the_o way_n of_o cure_n for_o beside_o that_o acidity_n which_o do_v very_o often_o breath_n through_o the_o mouth_n they_o suffer_v the_o gripe_n of_o the_o belly_n the_o milk_n may_v likewise_o be_v perceive_v to_o be_v concrete_v both_o upward_o and_o downward_o the_o excrement_n of_o the_o belly_n be_v more_o green_a and_o give_v forth_o a_o sharp_a odour_n they_o be_v also_o cure_v by_o the_o temper_n of_o acidity_n as_o for_o example_n with_o aqua_fw-la feniculi_fw-la aqua_fw-la lilliorun_n conuallium_fw-la spir._n salis_n armoniaci_fw-la etc._n etc._n the_o same_o more_o acid_n pancratick_a juice_n carry_v to_o the_o blood_n through_o the_o lactean_a vein_n will_v give_v it_o a_o great_a consistency_n whence_o the_o blood_n less_o rarify_n will_v produce_v a_o lesser_a pulse_n from_o which_o vice_n high_o exceed_v we_o judge_v a_o syncope_n sometime_o to_o be_v produce_v which_o be_v not_o a_o little_a confirm_v by_o that_o example_n which_o lazarus_n riverius_n relate_v in_o lib._n viii_o fol._n 358._o of_o his_o practice_n concern_v that_o syncope_n which_o p._n salius_n as_o he_o report_v lib._n de_fw-fr afect_v practic_n cap._n iv._o observe_v in_o a_o girl_n of_o 14_o year_n of_o age_n who_o after_o a_o day_n suffer_v of_o heaviness_n of_o the_o head_n vertigo_n and_o grievous_a anxiety_n the_o day_n follow_v sudden_o die_v afterward_o her_o body_n be_v diffect_v the_o whole_a blood_n in_o the_o great_a artery_n and_o the_o vena_fw-la cava_fw-la appear_v to_o be_v concrete_v and_o so_o change_v that_o it_o may_v entire_o be_v draw_v out_o from_o the_o vein_n and_o artery_n even_o as_o a_o sword_n out_o of_o its_o scabbard_n concern_v which_o thing_n if_o any_o doubt_n either_o by_o we_o or_o other_o example_n let_v he_o take_v a_o acid_a liquor_n and_o pour_v it_o by_o degree_n into_o the_o vein_n of_o any_o live_a dog_n and_o he_o shall_v not_o only_o observe_v the_o blood_n therein_o to_o be_v so_o coagulate_v and_o concrete_v that_o the_o great_a bloody_a vessel_n may_v be_v transvers_o cut_v without_o the_o effusion_n of_o the_o blood_n but_o also_o when_o the_o acid_a liquor_n shall_v come_v in_o a_o notable_a quantity_n to_o the_o right_a ventricle_n of_o the_o heart_n that_o it_o will_v present_o extinguish_v and_o kill_v the_o dog_n also_o no_o man_n will_v deny_v that_o convulsion_n for_o the_o most_o part_n proceed_v from_o a_o internal_a cause_n from_o the_o acrimony_n of_o humour_n irritate_v the_o nerve_n and_o cause_v by_o a_o great_a influx_n of_o the_o animal_n spirit_n into_o the_o muscle_n involuntary_a and_o also_o violent_a motion_n but_o when_o there_o be_v a_o two_o fold_v acrimony_n of_o humour_n viz._n acid_n and_o salt_n some_o perhaps_o may_v doubt_v which_o of_o these_o do_v most_o frequent_o produce_v those_o convulsive_a motion_n but_o for_o as_o much_o as_o we_o can_v observe_v they_o rather_o proceed_v from_o a_o acid_a acrimony_n than_o a_o salt_n because_o we_o see_v that_o aromatic_a medicament_n and_o those_o abound_v with_o a_o volatile_a salt_n do_v very_o much_o conduce_v to_o their_o cure_n which_o will_v never_o come_v to_o pass_v if_o they_o draw_v their_o original_a from_o a_o saline_n acrimony_n beside_o they_o be_v accompany_v with_o such_o symptom_n which_o be_v wont_a to_o be_v the_o concomitant_n of_o disease_n arise_v from_o a_o acid_a acrimony_n yea_o the_o effect_n of_o acid_n be_v allow_v to_o be_v far_o more_o powerful_a as_o be_v to_o be_v see_v in_o helmont_n de_fw-fr lithiasi_fw-la cap._n 9_o pag._n 725._o §_o 71._o where_o he_o relate_v that_o he_o see_v a_o chemist_n which_o after_o he_o have_v be_v much_o conversant_a about_o make_v of_o aqua_fw-la regius_fw-la he_o fall_v into_o the_o palpitation_n of_o the_o heart_n convulsion_n and_o many_o other_o incredible_a dolour_n by_o reason_n of_o the_o acid_a exhalation_n which_o mingle_v themselves_o with_o his_o blood_n from_o the_o same_o acidity_n we_o steadfast_o believe_v that_o the_o strangury_n be_v very_o often_o produce_v see_v that_o together_o with_o other_o student_n we_o have_v sometime_o find_v the_o urine_n of_o such_o as_o have_v labour_v under_o the_o strangury_n in_o the_o hospital_n of_o leyden_n to_o be_v acid_n and_o also_o see_v the_o same_o person_n cure_v with_o such_o medicine_n as_o temper_v acidity_n the_o which_o if_o you_o be_v mind_v to_o try_v say_v helmont_n de_fw-fr pleura_fw-la furente_fw-la §_o 14._o whether_o or_o no_o the_o strangury_n may_v not_o proceed_v from_o acidity_n mix_v some_o drop_n at_o least_o of_o sharp_a wine_n with_o the_o urine_n late_o send_v forth_o without_o pain_n and_o inject_v it_o again_o by_o a_o syringe_n and_o you_o shall_v find_v to_o your_o pain_n that_o what_o i_o say_v be_v true_a also_o that_o from_o the_o more_o acid_a pancreatic_a juice_n ulcer_n do_v sometime_o break_v forth_o in_o the_o skin_n corrode_a the_o same_o as_o also_o produce_v very_o great_a pain_n they_o will_v not_o deny_v who_o follow_v the_o opinion_n of_o the_o ancient_n determine_v they_o to_o arise_v from_o the_o atrabilis_a see_v that_o the_o atrabilis_a of_o the_o ancient_n as_o we_o have_v above_o demonstrate_v have_v its_o original_a from_o the_o more_o acid_a pancreatic_a juice_n we_o be_v likewise_o plain_o persuade_v that_o the_o more_o acid_a pancreatic_a juice_n especial_o if_o it_o have_v any_o austerity_n conjoin_v with_o it_o produce_v a_o great_a astringency_n of_o the_o belly_n for_o if_o the_o bile_n by_o its_o acrimony_n irritate_v the_o gut_n as_o be_v grant_v may_v excite_v the_o flux_n of_o the_o belly_n why_o may_v not_o that_o which_o be_v contrary_a to_o such_o a_o bile_n produce_v a_o contrary_a effect_n notwithstanding_o if_o the_o belly_n be_v bind_v by_o a_o viscid_a matter_n than_o we_o think_v likewise_o that_o a_o flux_n may_v happen_v from_o the_o sharp_a pancreatic_a juice_n as_o it_o have_v a_o power_n of_o incide_v and_o attenuate_a the_o viscid_a pituity_n from_o which_o it_o be_v manifest_a that_o the_o pancreatic_a juice_n according_a to_o the_o diversity_n of_o humour_n concur_v with_o it_o do_v very_o often_o produce_v a_o diverse_a and_o contrary_a effect_n which_o thing_n we_o will_v have_v well_o note_v lest_o we_o shall_v seem_v to_o contradict_v ourselves_o in_o explicate_v the_o effect_n of_o this_o juice_n as_o yet_o we_o think_v even_o as_o we_o seem_v to_o have_v already_o say_v that_o the_o atra_fw-la and_o eruginous_a bile_n be_v excite_v from_o the_o more_o acid_a pancreatic_a juice_n and_o a_o certain_a sharp_a bile_n concur_v and_o consequent_o all_o disease_n which_o author_n deduce_v from_o they_o and_o therefore_o they_o be_v not_o cure_v by_o other_o medicament_n than_o those_o which_o be_v fit_a to_o correct_v the_o more_o acid_a pancreatic_a juice_n which_o as_o it_o be_v consonant_a with_o reason_n so_o it_o will_v not_o appear_v incredible_a to_o those_o who_o will_v consider_v the_o thing_n above_o speak_v by_o we_o with_o a_o more_o attentive_a mind_n but_o perhaps_o some_o will_v say_v after_o what_o manner_n do_v the_o pancreatic_a juice_n produce_v the_o atrabilis_a see_v that_o we_o have_v ascribe_v the_o whitishness_n of_o the_o chyle_n after_o the_o effervescency_n in_o the_o thin_a gut_n to_o the_o acidity_n of_o the_o pancreatic_a juice_n to_o which_o we_o answer_v that_o acid_n according_a to_o the_o diversity_n of_o the_o matter_n wherewith_o they_o be_v mix_v do_v also_o produce_v a_o divers_a colour_n for_o example_n pour_v a_o acid_a spirit_n to_o common_a sulphur_n dissolve_v in_o a_o lixivium_n and_o its_o red_a colour_n will_v be_v change_v into_o white_a antimony_n calcind_n with_o nitre_n or_o chalk_n be_v boil_v in_o fountain-water_n and_o any_o acid_a thing_n be_v affuse_v to_o its_o clear_a colature_n will_v present_o acquire_v a_o saffron_n colour_n a_o clear_a infusion_n of_o gall_n mix_v with_o the_o solution_n of_o vitriol_n make_v ink_n to_o which_o if_o you_o add_v the_o acid_a spirit_n of_o vitriol_n that_o ink_n will_v lose_v all_o its_o blackness_n and_o become_v clear_a like_v to_o fountain-water_n the_o blue_a tincture_n of_o violet_n be_v mix_v with_o oil_n of_o vitriol_n will_v wax_v into_o a_o purple_a the_o wood_n acanthus_n bring_v from_o brasile_n be_v infuse_v in_o common_a water_n do_v free_o yield_v a_o red_a tincture_n which_o put_v to_o distil_v vinegar_n acquire_v a_o colour_n like_o to_o white-wine_n a_o knife_n after_o it_o have_v cut_v a_o pomecitron_n in_o the_o middle_a unless_o it_o be_v wipe_v and_o cleanse_v from_o the_o sour_a juice_n of_o the_o citron_n in_o a_o short_a time_n will_v be_v reduce_v to_o a_o nigrous_a colour_n and_o why_o from_o the_o same_o acidity_n too_o much_o exalt_v
therefore_o lest_o we_o consume_v our_o own_o and_o the_o reader_n time_n by_o write_v more_o thing_n obvious_a as_o well_o in_o the_o book_n of_o the_o ancient_n as_o in_o the_o modern_n we_o shall_v willing_o pass_v they_o by_o see_v that_o the_o cause_n of_o all_o intermit_a fever_n seem_v to_o we_o to_o be_v contain_v in_o the_o pancreas_fw-la alone_o the_o reason_n of_o this_o opinion_n be_v this_o that_o have_v consider_v the_o part_n of_o the_o whole_a body_n of_o man_n which_o by_o interval_n only_o may_v transmit_v the_o cause_n of_o these_o fever_n to_o the_o heart_n none_o can_v be_v find_v in_o the_o whole_a body_n to_o which_o not_o only_o the_o focus_n of_o intermit_a fever_n but_o also_o the_o cause_n of_o all_o their_o symptom_n may_v be_v impute_v beside_o the_o pancreas_n but_o some_o perhaps_o may_v say_v that_o heat_n thirst_n ulcer_n break_v forth_o in_o the_o lip_n of_o the_o feverish_a bitter_a vomit_n choleric_a excrement_n and_o other_o symptom_n wont_a to_o accompany_v tertain_v fever_n do_v declare_v the_o boil_n to_o be_v primary_o offend_v wherefore_o the_o cause_n of_o all_o intermit_a fever_n ought_v not_o to_o be_v ascribe_v to_o the_o pancrea_n alone_o but_o true_o this_o objection_n will_v fall_v of_o its_o own_o accord_n those_o thing_n be_v know_v which_o we_o shall_v speak_v of_o in_o the_o follow_a discourse_n concern_v the_o reason_n of_o divers_a symptom_n for_o we_o know_v that_o in_o tertian_n the_o boil_n be_v very_o often_o predominant_a but_o it_o be_v to_o be_v note_v that_o its_o abundance_n do_v not_o cause_v a_o intermit_a fever_n because_o that_o be_v perceive_v after_o it_o have_v excite_v a_o vicious_a effervesency_n by_o interval_n with_o the_o pancreatic_a juice_n in_o which_o if_o the_o boil_n get_v dominion_n the_o sign_n thereof_o even_o now_o declare_v do_v sometime_o manifest_v themselves_o but_o because_o this_o effervescency_n proceed_v from_o the_o pancreatic_a juice_n preternatural_o dispose_v that_o fever_n be_v not_o ascribe_v to_o the_o bile_n but_o to_o the_o pancreatic_a juice_n as_o by_o the_o sequel_n shall_v more_o plain_o appear_v we_o judge_v the_o cause_n of_o intermit_a fever_n to_o be_v a_o obstruction_n make_v in_o one_o or_o more_o of_o the_o lateral_a duct_n because_o of_o pituity_n carry_v thither_o in_o too_o large_a a_o quantity_n and_o there_o detain_v which_o thing_n seem_v to_o we_o to_o happen_v for_o the_o follow_a reason_n to_o wit_n for_o as_o much_o as_o the_o pituity_n of_o the_o thin_a gut_n especial_o that_o stick_n to_o the_o side_n lest_o they_o shall_v be_v hurt_v by_o the_o abound_a humour_n be_v in_o too_o great_a a_o quantity_n by_o reason_n of_o the_o immoderate_a exercise_n of_o the_o body_n and_o perhaps_o by_o a_o overmuch_o use_v of_o hot_a aliment_n or_o by_o some_o error_n commit_v in_o the_o six_o non-naturals_a be_v dissolve_v and_o with_o other_o humour_n carry_v to_o the_o heart_n by_o the_o milky_a vein_n from_o whence_o by_o the_o order_n of_o circulation_n this_o phlegmatic_a matter_n together_o with_o the_o rest_n of_o the_o blood_n be_v drive_v to_o the_o pancreas_n and_o be_v separate_v in_o its_o glandule_n with_o the_o pancreatic_a juice_n it_o enter_v the_o lateral_a duct_n of_o the_o pancreas_n in_o which_o either_o by_o the_o external_n cold_a or_o of_o that_o bowel_v it_o concrete_v and_o be_v coagulate_v by_o which_o reason_n it_o obstruct_v either_o one_o or_o more_o of_o the_o lateral_a duct_n we_o think_v the_o access_n of_o intermit_a fever_n aught_o to_o be_v ascribe_v to_o the_o pancreatic_a juice_n stagnant_a in_o one_o or_o more_o of_o the_o lateral_a duct_n by_o reason_n of_o a_o obstruction_n and_o one_o while_n soon_o another_o while_n late_a prepare_v a_o way_n for_o itself_o through_o the_o obstruct_v phlegm_n by_o its_o acrimony_n increase_v and_o not_o only_o cause_v a_o vicious_a effervescency_n in_o the_o small_a gut_n but_o be_v every_o way_n carry_v especial_o to_o the_o heart_n produce_v a_o more_o frequent_a and_o preternatural_a pulse_n which_o that_o it_o may_v more_o clear_o appear_v we_o shall_v spend_v a_o little_a time_n in_o the_o unfolding_n thereof_o that_o coagulation_n which_o we_o have_v mention_v to_o happen_v in_o the_o pancreatic_a juice_n we_o have_v sometime_n observe_v in_o a_o dog_n who_o juice_n we_o endeavour_v to_o collect_v in_o the_o winter_n time_n which_o by_o the_o cold_a of_o the_o ambient_fw-la air_n be_v so_o thicken_v that_o only_o a_o little_a will_v flow_v forth_o and_o of_o a_o gross_a consistency_n until_o the_o dog_n be_v place_v before_o the_o fire_n between_o two_o pillow_n begin_v to_o grow_v hot_a from_o whence_o the_o pancreatic_a juice_n do_v flow_v more_o fluid_a and_o more_o copious_o we_o have_v observe_v that_o the_o coagulation_n of_o the_o pancreatic_a juice_n have_v excite_v obstruction_n in_o the_o lateral_a duct_n of_o the_o pancreas_n as_o in_o the_o year_n 1663._o with_o the_o famous_a dr._n silvius_n in_o a_o certain_a woman_n labour_v under_o a_o intermit_a fever_n into_o who_o ductus_fw-la pancreaticus_fw-la after_o death_n we_o inject_v by_o a_o syringe_n a_o very_a volatile_a bluish_a liquor_n which_o out_o of_o the_o great_a dust_n into_o which_o it_o be_v cast_v do_v penetrate_v into_o most_o of_o the_o lateral_a duct_n whilst_o in_o a_o few_o although_o more_o near_o to_o the_o intestinal_n great_a dust_n by_o reason_n of_o a_o obstruction_n it_o be_v stop_v from_o whence_o by_o the_o say_a colour_n the_o substance_n of_o the_o pancreas_n itself_o be_v tinge_v in_o one_o place_n and_o not_o in_o another_o the_o pancreatic_a juice_n be_v stagnant_a in_o one_o or_o more_o of_o the_o lateral_a duct_n by_o reason_n of_o a_o obstruction_n by_o its_o delay_n become_v more_o sharp_a and_o at_o length_n perforate_n the_o obstruct_v phlegm_n prepare_v itself_o a_o passage_n through_o the_o obstruction_n into_o the_o common_a or_o middle_a dust_n until_o all_o the_o detain_v juice_n be_v effuse_v the_o phlegm_n as_o yet_o adhere_v to_o the_o side_n of_o the_o dust_n grow_v together_o again_o and_o by_o its_o mutual_a reunion_n renew_v the_o obstruction_n whence_o at_o length_n the_o pancreatic_a juice_n be_v collect_v for_o the_o follow_v fit_a which_o again_o by_o its_o delay_n be_v make_v more_o sharp_a do_v again_o perforate_a the_o obstruct_v pituity_n and_o produce_v a_o new_a paroxysm_n which_o fit_v return_v always_o at_o the_o same_o time_n as_o often_o as_o the_o pituity_n cause_v the_o obstruction_n do_v occur_v in_o the_o same_o quantity_n and_o viscidity_n with_o the_o pancreatic_a juice_n of_o the_o same_o acidity_n and_o acrimony_n the_o pancreatic_a juice_n be_v make_v more_o sharp_a by_o stagnation_n in_o as_o much_o as_o the_o animal_n spirit_n do_v not_o so_o straight_o embrace_v it_o but_o leave_v it_o obstruct_v hence_o therefore_o by_o the_o dissipate_v spirit_n wont_a to_o attemper_v it_o there_o redound_v a_o great_a acidity_n of_o the_o pancreatic_a juice_n will_v you_o have_v a_o simillitude_n we_o will_v grant_v it_o new_a ale_n include_v in_o hogshead_n whether_o or_o no_o by_o a_o certain_a delay_n it_o do_v not_o lose_v its_o sweetness_n consider_v that_o all_o wine_n turn_v to_o vinegar_n the_o spirit_n be_v dissipate_v also_o that_o vinegar_n itself_o by_o delay_n be_v make_v more_o sharp_a for_o every_o heat_n dissipate_v the_o animal_n spirit_n cause_v every_o sharp_a thing_n to_o be_v more_o sharp_a so_o that_o it_o ought_v to_o seem_v strange_a to_o none_o if_o we_o say_v that_o the_o pancreatic_a juice_n by_o stagnation_n desert_v its_o genuine_a disposition_n and_o pass_v into_o a_o more_o acid_a acrimony_n but_o the_o pancreatic_a juice_n be_v make_v more_o sharp_a by_o stagnation_n and_o effuse_v into_o the_o thin_a gut_n with_o the_o flegmme_n and_o bile_n stir_v up_o a_o vicious_a effervescency_n and_o indeed_o by_o reason_n of_o such_o a_o pancreatic_a juice_n stretching_n yawning_n and_o horror_n be_v produce_v and_o everywhere_o a_o sense_n of_o cold_a especial_o in_o the_o region_n of_o the_o loin_n in_o which_o the_o fit_a begin_v neither_o be_v that_o first_o call_v a_o fever_n which_o either_o the_o pancreatic_a juice_n itself_o vicious_o effervesce_v in_o the_o small_a gut_n or_o at_o least_o exhalation_n from_o thence_o arise_v and_o at_o length_n carry_v to_o the_o right_a ventricle_n of_o the_o heart_n and_o after_o a_o certain_a manner_n irritate_v it_o to_o a_o more_o frequent_a contraction_n of_o itself_o but_o we_o judge_v that_o the_o pancreatic_a juice_n by_o its_o acid_a acrimony_n perform_v this_o thing_n although_o nothing_o hinder_v but_o that_o something_o of_o a_o saline_n acrimony_n arise_v from_o the_o bile_n may_v concur_v because_o we_o daily_o observe_v that_o exhalation_n do_v ascend_v in_o the_o effervescency_n between_o acid_n and_o salt_n which_o be_v move_v to_o the_o nose_n by_o its_o