of_o the_o reconcileableness_n of_o specific_a medicine_n to_o the_o corpuscular_a philosophy_n to_o which_o be_v annex_v a_o discourse_n about_o the_o advantage_n of_o the_o use_n of_o simple_z medicine_n by_o the_o honourable_a robert_n boyle_n fellow_n of_o the_o royal_a society_n london_n print_v for_o sam._n smith_n at_o the_o prince_n arm_n in_o st._n paul_n churchyard_n 1685._o august_n 24._o imprimatur_fw-la hen._n maurice_n rmo_z d_o â—o_z w._n cant._n arch_n po_fw-la a_o sacris_fw-la the_o preface_n the_o rise_n of_o the_o follow_a tract_n intimate_v near_o the_o begin_n of_o it_o be_v not_o such_o a_o fictitious_a thing_n as_o the_o reader_n may_v imagine_v but_o though_o i_o real_o receive_v a_o visit_n from_o a_o physician_n know_v to_o i_o but_o by_o his_o reputation_n purposely_o to_o propose_v to_o i_o his_o objection_n against_o the_o corpuscular_a philosophy_n and_o he_o have_v a_o long_a conference_n with_o i_o about_o they_o yet_o because_o the_o historical_a 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produce_v by_o natural_a cause_n in_o the_o body_n of_o a_o animal_n whilst_o the_o physician_n consider_v they_o as_o symptom_n of_o disease_n or_o effect_n of_o medicine_n the_o former_a direct_v his_o speculation_n to_o the_o discovery_n of_o truth_n and_o the_o other_o his_o theory_n to_o the_o recovery_n of_o health_n but_o because_o i_o else_o where_o particular_o consider_v the_o cognation_n and_o distinction_n between_o the_o discipline_n that_o the_o naturalist_n and_o that_o which_o the_o physician_n cultivate_v i_o shall_v for_o bear_v to_o mention_v they_o in_o this_o place_n but_o rather_o acknowledge_v that_o i_o scarce_o doubt_v but_o that_o i_o may_v have_v enrich_v the_o follow_a discourse_n with_o some_o choice_a particular_n if_o i_o will_v have_v peruse_v and_o borrow_a from_o the_o learned_a write_n of_o the_o famous_a dr._n willis_n but_o beside_o that_o i_o have_v not_o his_o book_n at_o hand_n i_o be_v unwilling_a to_o be_v prepossess_v or_o bias_v by_o his_o notion_n and_o i_o presume_v the_o person_n i_o write_v to_o will_v not_o be_v unwilling_a to_o see_v what_o without_o their_o help_n the_o consideration_n of_o the_o thing_n i_o treat_v of_o suggest_a to_o i_o about_o this_o i_o shall_v now_o proceed_v to_o observe_v that_o though_o the_o direct_a scope_n of_o the_o follow_a discourse_n be_v to_o explicate_v the_o phaenomena_n of_o some_o body_n which_o from_o their_o use_n be_v call_v medicinal_a and_o declare_v how_o possible_o they_o may_v produce_v the_o effect_n ascribe_v to_o they_o the_o ensue_a discourse_n be_v for_o the_o main_a of_o a_o speculative_a nature_n yet_o the_o consequence_n that_o may_v be_v draw_v from_o it_o and_o the_o application_n that_o in_o this_o industrious_a age_n be_v like_a to_o be_v make_v of_o some_o thing_n that_o it_o contain_v may_v probable_o render_v it_o practical_a for_o i_o have_v more_o than_o once_o observe_v that_o divers_a considerable_a remedy_n and_o some_o not_o unpromise_v method_n 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many_o age_n think_v to_o be_v ground_v upon_o no_o less_o authority_n than_o a_o positive_a aphorism_n of_o hypocrates_n and_o therefore_o if_o to_o remove_v the_o specious_a objection_n new_o mention_v against_o that_o whole_a kind_n of_o remedy_n call_v specific_v the_o follow_a tract_n have_v be_v so_o happy_a as_o to_o show_v that_o it_o be_v at_o lest_o possible_a that_o medicine_n say_v to_o be_v specific_a may_v perform_v their_o operation_n by_o way_n which_o though_o not_o explicable_a by_o the_o vulgar_a doctrine_n of_o the_o school_n be_v intelligible_a and_o reconcileable_a to_o the_o clear_a principle_n of_o the_o mechanical_a philosophy_n if_o i_o say_v this_o have_v be_v do_v by_o the_o theory_n propose_v in_o this_o treatise_n it_o may_v conduce_v somewhat_o to_o enlarge_v the_o mind_n of_o many_o physician_n and_o invite_v they_o to_o make_v use_n of_o several_a remedy_n of_o which_o they_o do_v not_o think_v or_o against_o which_o they_o be_v prejudice_v and_o since_o specific_v where_o they_o can_v be_v have_v be_v wont_a to_o be_v free_a from_o any_o immoderate_a manifest_a quality_n and_o for_o the_o most_o part_n to_o work_v more_o benign_o as_o well_o as_o more_o effectual_o caeteris_fw-la paribus_fw-la than_o other_o medicine_n i_o think_v that_o to_o bring_v they_o into_o due_a request_n and_o invite_v physician_n to_o search_v for_o new_a one_o as_o well_o as_o employ_v those_o already_o know_v may_v tend_v much_o to_o shorten_v many_o cure_n and_o make_v they_o more_o easy_a and_o more_o safe_a est_fw-la aliquid_fw-la prodire_fw-la tenus_fw-la si_fw-la non_fw-la datur_fw-la ultra_fw-la the_o advertisement_n of_o the_o publisher_n the_o author_n have_v occasion_n to_o touch_v upon_o some_o of_o the_o same_o subject_n that_o he_o here_o treat_v of_o in_o a_o book_n the_o usefulness_n of_o experimental_a philosophy_n long_o since_o publish_v but_o he_o have_v the_o misfortune_n to_o be_v reduce_v to_o write_v the_o follow_a discourse_n about_o specific_a medicine_n and_o the_o utility_n of_o simple_a remedy_n in_o a_o village_n where_o he_o have_v not_o that_o book_n at_o hand_n and_o can_v not_o call_v to_o mind_v all_o that_o he_o have_v therein_o publish_v seventeen_o or_o eighteen_o year_n before_o on_o which_o account_n though_o he_o studious_o forbear_v to_o repeat_v the_o particular_n that_o he_o remember_v to_o have_v set_v down_o in_o that_o treatise_n how_o opposite_a soever_o they_o will_v have_v be_v to_o his_o present_a purpose_n yet_o have_v since_o the_o follow_a discourse_n be_v send_v to_o the_o press_n get_v a_o sight_n of_o that_o other_o which_o he_o have_v not_o read_v in_o many_o year_n he_o find_v upon_o a_o transient_a view_n that_o some_o of_o the_o same_o thing_n be_v mention_v in_o both_o book_n at_o which_o discovery_n though_o he_o be_v somewhat_o trouble_v yet_o he_o be_v the_o less_o so_o because_o they_o be_v but_o few_o in_o comparison_n of_o the_o new_a one_o and_o set_v
advertisement_n i_o presume_v i_o may_v offer_v you_o two_o or_o three_o consideration_n that_o may_v lessen_v the_o force_n of_o the_o late_o propose_v objection_n and_o first_o though_o i_o ready_o grant_v that_o there_o be_v disease_n whereof_o each_o may_v proceed_v from_o differ_v cause_n and_o that_o a_o remedy_n may_v be_v available_a against_o it_o when_o it_o be_v produce_v by_o one_o of_o those_o cause_n without_o be_v so_o when_o it_o flow_v from_o another_o yet_o it_o may_v also_o easy_o happen_v that_o in_o one_o case_n the_o disease_n may_v be_v cure_v by_o one_o simple_a medicine_n and_o in_o another_o by_o a_o remedy_n not_o compound_v nay_o it_o may_v also_o happen_v that_o the_o same_o simple_a may_v cure_v a_o distemper_n by_o which_o soever_o of_o the_o two_o cause_n it_o be_v produeed_o this_o i_o have_v in_o another_o paper_n endeavour_v to_o make_v out_o and_o what_o we_o see_v of_o the_o effect_n of_o the_o jesuit_n powder_n as_o they_o call_v it_o in_o different_a kind_n of_o ague_n as_o tertian_n quartan_n etc._n etc._n and_o of_o pacate_a medicine_n most_o of_o which_o indeed_o owe_v their_o virtue_n to_o opium_n but_o some_o be_v mineral_n and_o have_v nothing_o of_o the_o poppy_n in_o they_o in_o appease_v pain_n produce_v by_o humour_n and_o other_o cause_n very_o differ_v may_v keep_v what_o have_v be_v say_v from_o appear_v improbable_a and_o if_o i_o mistake_v not_o it_o may_v divers_a time_n happen_v that_o whatever_o it_o be_v that_o at_o first_o produce_v a_o portion_n of_o morbific_n matter_n that_o first_o produce_v matter_n be_v the_o cause_n of_o the_o continuance_n of_o the_o disease_n by_o virtue_n of_o some_o peculiar_a texture_n or_o noxious_a constitution_n which_o if_o a_o generous_a medicine_n can_v destroy_v the_o disease_n will_v at_o least_o little_a by_o little_a cease_v 3._o it_o not_o unfrequent_o happen_v that_o several_a symptom_n that_o seem_v very_o differ_v may_v so_o depend_v upon_o the_o primary_n or_o principal_a cause_n of_o the_o disease_n that_o if_o a_o medicine_n how_o simple_a soever_o be_v capable_a to_o destroy_v that_o cause_n all_o the_o various_a symptom_n will_v by_o degree_n at_o least_o vanish_v of_o themselves_o as_o we_o often_o see_v that_o when_o mercury_n though_o perhaps_o but_o crude_a be_v skilful_o apply_v and_o raise_v a_o kindly_a salivation_n a_o great_a variety_n of_o inconvenience_n that_o afflict_v a_o venereal_a patient_n and_o seem_v to_o require_v many_o differ_v and_o topical_a application_n be_v remove_v by_o the_o same_o remedy_n insomuch_o that_o not_o only_o frightful_a ulcer_n but_o such_o mode_n as_o one_o will_v think_v searce_o possible_a to_o be_v dissipate_v by_o the_o strong_a plaster_n be_v sometime_o happy_o cure_v by_o well_o prepare_v quicksilver_n take_v in_o at_o the_o mouth_n as_o i_o have_v be_v assure_v by_o more_o than_o one_o eminent_a physician_n upon_o his_o own_o experience_n and_o though_o not_o unfrequent_o there_o be_v several_a &_o sometime_o very_o different_a symptom_n that_o accompany_v that_o disease_n of_o child_n that_o in_o england_n we_o call_v the_o rickets_o and_o of_o which_o there_o die_v several_a almost_o every_o week_n in_o london_n alone_a yet_o that_o medicine_n which_o i_o have_v elsewhere_o describe_v under_o the_o name_n of_o ens_fw-la primum_fw-la veneris_fw-la make_v of_o strong_o calcine_v and_o well_o dulcify_v colcothar_n of_o dantsick_a vitriol_n and_o elevate_v with_o sal_fw-la ammoniac_a into_o the_o form_n of_o a_o red_a sublimate_n have_v prove_v by_o god_n blessing_n on_o it_o so_o successful_a that_o partly_o by_o a_o sister_n of_o i_o to_o who_o i_o communicate_v it_o and_o partly_o by_o myself_o and_o those_o i_o direct_v to_o take_v it_o or_o to_o give_v it_o i_o think_v i_o may_v safe_o say_v that_o two_o or_o three_o hundred_o child_n have_v be_v cure_v by_o it_o and_o that_o almost_o always_o without_o the_o help_n of_o any_o other_o inward_a medicine_n or_o use_v any_o topical_a application_n at_o all_o 4._o but_o the_o main_a thing_n that_o i_o intend_v by_o way_n of_o answer_n to_o the_o foresee_a objection_n be_v that_o in_o a_o simple_a medince_n nature_n herself_o do_v oftentimes_o so_o well_o play_v the_o apothecary_n as_o to_o render_v the_o composition_n make_v in_o his_o shop_n unnecessary_a for_o though_o we_o be_v wont_n to_o look_v upon_o this_o or_o that_o plant_n or_o mineral_n as_o a_o entire_a and_o simple_a body_n yet_o we_o may_v much_o mistake_v if_o we_o look_v upon_o it_o as_o a_o homogeneous_a one_o in_o several_a plant_n that_o be_v organical_a body_n this_o truth_n be_v manifest_a as_o for_o instance_n in_o orange_n the_o succulent_a part_n be_v sour_a and_o cool_a but_o the_o yellow_a rind_n considerable_o bitter_a and_o hot_a and_o so_o in_o lemon_n the_o pulp_n the_o yellow_a part_n of_o the_o rind_n and_o the_o seed_n have_v their_o differ_a quality_n and_o medicinal_a virtue_n and_o even_o in_o such_o vegetable_a substance_n as_o be_v homogeneous_a as_o to_o sense_n there_o may_v be_v part_n who_o operation_n may_v be_v not_o only_o differ_v but_o contrary_a as_o be_v manifest_a in_o the_o root_n we_o call_v rhubarb_n which_o afford_v as_o well_o notable_o astringent_a as_o laxative_a and_o purgative_n part_n and_o so_o in_o mineral_n themselves_o good_a and_o clean_a lead-oar_n for_o instance_n though_o a_o uniform_a body_n as_o to_o sense_n consist_v of_o very_o dissimilar_v part_n and_o afford_v sulphureous_a and_o perhaps_o other_o recrement_n beside_o malleable_a lead_n which_o be_v itself_o a_o compound_a body_n thus_o also_o shine_v marcasite_n though_o they_o appear_v homogeneous_a will_v by_o bare_o be_v expose_v for_o a_o competent_a time_n to_o the_o moist_a air_n afford_v a_o efflorescence_n that_o be_v perfect_o vitriolate_v and_o consequent_o contain_v a_o acid_n salt_n two_o kind_n of_o sulphur_n a_o terrestrial_a substance_n and_o at_o least_o one_o metal_n for_o oftentimes_o it_o hold_v both_o copper_n and_o iron_n though_o one_o predominate_v which_o last_v name_v substance_n themselves_o be_v neither_o of_o they_o simple_a body_n 5._o and_o if_o we_o admit_v the_o chemical_a analysis_n of_o mixt_n to_o be_v genuine_a we_o shall_v find_v that_o almost_o all_o those_o that_o belong_v to_o the_o vegetable_a kingdom_n or_o to_o the_o animal_n and_o many_o that_o be_v refer_v to_o the_o mineral_n kingdom_n how_o uniform_a soever_o they_o may_v appear_v to_o the_o eye_n do_v each_o of_o they_o contain_v several_a different_a and_o sometime_o hostile_a substance_n thus_o hartshorn_n though_o it_o appear_v a_o dry_a and_o homogeneous_a substance_n will_v in_o distillation_n afford_v a_o volatile_a salt_n a_o urinous_a spirit_n a_o waterish_a liquor_n or_o phlegm_n a_o swim_a oil_n and_o a_o sink_a one_o a_o white_a and_o porous_a earth_n or_o terra_fw-la damnata_fw-la and_o perhaps_o some_o though_o but_o very_o little_a fix_v salt_n thus_o also_o in_o the_o vegetable_a kingdom_n tartar_n for_o instance_n may_v without_o addition_n be_v make_v to_o afford_v as_o experience_n have_v assure_v i_o a_o volatile_a salt_n very_o like_o that_o of_o urine_n a_o phlegm_n a_o acid_n spirit_n another_o spirit_n too_o which_o i_o have_v elsewhere_o give_v the_o name_n of_o adiaphorous_a two_o fetid_v oil_n whereof_o one_o will_v sink_v in_o water_n and_o the_o other_o swim_v on_o it_o a_o earth_n or_o terra_fw-la damnata_fw-la and_o a_o fix_a lixivial_a salt_n upon_o which_o the_o new_o mention_v acid_n spirit_n manifest_v such_o a_o hostility_n that_o when_o they_o be_v put_v together_o they_o tumultuate_v with_o noise_n and_o bubble_n and_o in_o the_o conflict_n mortify_v each_o other_o and_o thus_o likewise_o in_o the_o mineral_n kingdom_n not_o to_o repeat_v what_o i_o late_o say_v of_o the_o compoundedness_n of_o vitriol_n nor_o confident_o to_o urge_v the_o opinion_n of_o divers_a eminent_a physician_n that_o mars_n as_o they_o call_v steel_n and_o iron_n afford_v part_n whereof_o some_o be_v astringent_a and_o other_o operative_a because_o i_o be_o not_o yet_o sure_a these_o contrary_a quality_n do_v not_o proceed_v from_o the_o differ_a degree_n of_o fire_n and_o other_o circumstance_n of_o the_o preparation_n of_o the_o metal_n we_o see_v that_o native_a cinnabar_fw-la afford_v by_o distillation_n beside_o run_v mercury_n a_o dry_a substance_n whence_o i_o have_v obtain_v a_o sulphur_n that_o will_v present_o gild_v silver_n and_o a_o terrestrial_a substance_n who_o nature_n i_o have_v not_o occasion_n to_o examine_v and_o i_o the_o rather_o take_v notice_n of_o these_o differ_a part_n in_o native_a cinnabar_fw-la because_o it_o be_v a_o mineral_n that_o i_o much_o esteem_v and_o though_o here_o in_o england_n it_o be_v very_o rare_o or_o scarce_o at_o all_o employ_v as_o a_o inward_a medicine_n yet_o i_o know_v some_o foreign_a physician_n of_o several_a nation_n that_o look_v upon_o it_o as_o one_o of_o their_o
have_v be_v enforce_v that_o i_o know_v a_o young_a man_n who_o have_v be_v bite_v by_o a_o english_a viper_n which_o he_o too_o rash_o lay_v hold_v on_o though_o the_o tooth_n prick_v but_o his_o hand_n yet_o the_o venom_n convey_v by_o so_o small_a a_o hurt_n which_o perhaps_o equal_v not_o in_o quantity_n the_o hundred_o part_n of_o pin_n head_n quick_o produce_v in_o he_o the_o bad_a symptom_n that_o usual_o follow_v the_o bite_v of_o that_o serpent_n and_o among_o other_o for_o i_o particular_o ask_v he_o about_o that_o a_o violent_a vomit_v of_o ill_a condition_a stuff_n i_o know_v also_o a_o person_n that_o practise_v physic_n in_o the_o isle_n of_o java_n where_o scorpion_n be_v hold_v to_o be_v more_o venomous_a than_o in_o italy_n who_o have_v after_o he_o have_v drink_v some_o what_o free_o provoke_v and_o be_v sting_v by_o a_o scorpion_n tho'_o the_o hurt_a be_v but_o in_o his_o thumb_n and_o be_v so_o small_a that_o i_o can_v not_o perceive_v the_o least_o scar_n it_o have_v leave_v that_o it_o put_v he_o present_o to_o such_o violent_a torture_n for_o some_o hour_n till_o he_o have_v procure_v specific_a remedy_n that_o he_o look_v upon_o himself_o a_o dead_a man_n and_o feel_v so_o rage_v a_o heat_n within_o that_o he_o think_v to_o use_v his_o own_o expression_n that_o hellfire_n be_v get_v into_o his_o body_n nor_o be_v it_o only_o by_o mere_a poison_n that_o a_o humane_a body_n may_v be_v great_o affect_v tho'_o the_o agent_n be_v but_o very_o inconsiderable_a for_o bulk_n and_o weight_n for_o we_o see_v that_o divers_a woman_n otherwise_o strong_a and_o healthy_a will_v be_v cast_v into_o sound_a fit_n and_o perhaps_o will_v complain_v of_o suffocation_n and_o be_v put_v into_o convulsive_a motion_n by_o the_o fragrant_a odour_n of_o musk_n or_o civet_n though_o if_o all_o the_o effluvia_fw-la that_o cause_n these_o symptom_n be_v reduce_v into_o one_o aggregate_v this_o will_v not_o probable_o amount_v to_o a_o hundred_o nor_o perhaps_o to_o a_o thousand_o part_n of_o a_o grain_n and_o i_o have_v oftentimes_o speedy_o suppress_v such_o fit_n by_o the_o odour_n of_o the_o volatile_a salt_n hartshorn_n shall_v ammoniac_a or_o the_o like_a or_o of_o distil_v spirit_n abound_v with_o such_o salt_n though_o perhaps_o all_o the_o particle_n that_o actual_o relieve_v the_o patient_a and_o calm_v these_o frightful_a symptom_n if_o pack_v together_o will_v not_o have_v equal_v either_o in_o bigness_n or_o in_o weight_n the_o ten_o not_o to_o say_v the_o fifteen_o or_o the_o hundred_o part_n of_o a_o grain_n of_o mustardseed_n and_o as_o for_o inward_a remedy_n it_o be_v vulgar_o know_v that_o in_o the_o infusion_n of_o crocus_n metallorum_fw-la corpuscle_n that_o render_v the_o liquor_n vehement_o vomitive_a and_o purgative_n be_v so_o very_a minute_n that_o great_a proportion_n of_o wine_n or_o other_o vehicles_n may_v be_v strong_o impregnate_v with_o they_o without_o any_o sensible_a diminution_n of_o the_o body_n that_o part_n with_o they_o and_o of_o this_o we_o have_v a_o not_o less_o if_o not_o more_o considerable_a instance_n when_o quicksilver_n be_v decoct_v or_o long_o infuse_v in_o common_a water_n for_o helmont_n observe_v that_o though_o the_o liquor_n be_v not_o alter_v in_o colour_n or_o taste_v nor_o the_o quicksilver_n at_o all_o sensible_o change_v nay_o nor_o grow_v any_o thing_n light_a in_o a_o balance_n yet_o the_o liquor_n do_v by_o mean_n of_o these_o insensible_a and_o unponderable_a efflux_n of_o the_o quicksilver_n acquire_v a_o notable_a virtue_n against_o worm_n for_o which_o purpose_v not_o only_a helmont_n but_o before_o he_o that_o experience_a chemist_n hartman_n and_o another_o eminent_a writer_n extol_v this_o medicine_n and_o on_o this_o occasion_n i_o remember_v that_o a_o fine_a boy_n bear_v to_o be_v heir_n to_o a_o very_a illustrious_a family_n fall_v into_o a_o dangerous_a fever_n which_o be_v judge_v to_o proceed_v from_o worm_n or_o verminous_a matter_n a_o famous_a and_o experience_a physician_n that_o treat_v he_o confess_v to_o i_o that_o he_o be_v out_o of_o hope_n of_o he_o because_o the_o child_n have_v be_v breed_v to_o have_v his_o will_n and_o tire_v with_o unsuccessful_a remedy_n be_v so_o obstinate_a and_o careful_a in_o refuse_v to_o take_v any_o thing_n that_o smell_v or_o relish_v of_o a_o medicine_n that_o he_o forbear_v in_o spite_n of_o all_o the_o be_v use_v to_o deceive_v he_o even_o to_o drink_v any_o thing_n but_o small_a beer_n whereupon_o i_o persuade_v both_o the_o doctor_n and_o the_o lord_n who_o son_n the_o child_n be_v to_o impregnate_n his_o small_a beer_n with_o mercurial_a particle_n by_o frequent_o shake_v it_o with_o good_a quicksilver_n in_o it_o by_o which_o mean_v the_o patient_a perceive_v no_o change_n of_o colour_n or_o taste_v in_o the_o drink_n swallow_v it_o greedy_o and_o through_o the_o blessing_n of_o god_n be_v soon_o after_o restore_v to_o a_o health_n which_o the_o party_n concern_v ascribe_v to_o the_o mercurial_a remedy_n i_o shall_v condemn_v myself_o for_o have_v bestow_v so_o many_o word_n upon_o one_o objection_n but_o that_o i_o hope_v the_o answer_n give_v to_o it_o in_o this_o place_n will_v facilitate_v and_o shorten_v several_a thing_n relate_v to_o my_o present_a subject_a specific_a medicine_n about_o which_o i_o shall_v now_o proceed_v to_o offer_v my_o thought_n in_o some_o proposition_n and_o short_a discourse_n upon_o they_o have_v now_o dispatch_v the_o first_o of_o the_o two_o former_o propose_v inquiry_n i_o proceed_v to_o the_o second_o namely_o whether_o the_o mechanical_a hypothesis_n can_v be_v accommodate_v to_o specific_a medicine_n so_o as_o that_o they_o may_v be_v either_o intelligible_o explicate_v by_o a_o or_o at_o least_o show_v to_o be_v reconcilable_a to_o it_o i_o presume_v you_o will_v easy_o believe_v that_o there_o be_v few_o writer_n more_o inclinable_a than_o i'am_n to_o confess_v the_o dimness_n of_o our_o knowledge_n and_o the_o obscurity_n of_o many_o thing_n in_o nature_n or_o that_o be_v more_o forward_o than_o i_o to_o grant_v that_o many_o of_o the_o operation_n of_o specific_a medicine_n be_v to_o be_v reckon_v among_o those_o abstruse_a thing_n whereof_o nature_n seem_v to_o affect_v the_o concealment_n but_o notwithstanding_o this_o when_o i_o consider_v how_o comprehensive_a and_o fertile_a the_o principle_n of_o the_o corpuscular_a philosophy_n be_v i_o can_v despair_v burr_n that_o it_o will_v be_v find_v that_o divers_a of_o the_o effect_n of_o these_o medicine_n may_v be_v in_o a_o general_a way_n explicate_v by_o they_o and_o not_o any_o will_v appear_v inconsistent_a with_o they_o this_o i_o desire_v may_v be_v here_o take_v notice_n of_o once_o for_o all_o that_o retain_v the_o scope_n of_o the_o follow_a discourse_n still_o in_o your_o memory_n you_o may_v not_o think_v it_o strange_a that_o i_o content_v myself_o on_o most_o occasion_n to_o give_v in_o general_a possible_a explication_n and_o to_o show_v that_o specific_a medicine_n may_v operate_v on_o some_o such_o account_n as_o i_o propose_v without_o affirm_v that_o they_o certain_o do_v so_o i_o observe_v soon_o after_o the_o begin_n of_o this_o paper_n that_o there_o be_v three_o sort_n of_o virtue_n to_o which_o physician_n tho'_o not_o unanimous_o have_v give_v this_o title_n of_o specific_a namely_o such_o as_o evacuate_v some_o particular_a humour_n such_o as_o be_v peculiar_o friendly_a to_o this_o or_o that_o part_n of_o the_o humane_a body_n and_o such_o as_o in_o a_o unknown_a way_n cure_n or_o much_o lessen_v this_o or_o that_o determinate_a disease_n but_o yet_o i_o shall_v now_o apply_v my_o discourse_n peculiar_o to_o the_o last_o sort_n of_o these_o medicine_n as_o be_v both_o more_o considerable_a in_o itself_o and_o the_o chief_a subject_n intend_v in_o present_a discourse_n give_v nevertheless_o as_o occasion_n serve_v such_o additional_a hint_n and_o observation_n as_o may_v make_v the_o reflection_n belong_v to_o this_o three_o sort_n of_o specific_v easy_o applicable_a mutatis_fw-la mutandis_fw-la to_o the_o other_o two_o and_o i_o shall_v begin_v with_o lay_v here_o for_o a_o foundation_n what_o i_o have_v in_o another_o treatise_n have_v occasion_n to_o deliver_v and_o make_v out_o namely_o that_o a_o live_a humane_a body_n be_v not_o to_o be_v look_v upon_o as_o a_o mere_a statue_n or_o a_o mere_a congery_n of_o the_o material_n it_o be_v compose_v of_o flesh_n blood_n bones_o fat_a nerve_n vein_n artery_n etc._n etc._n but_o a_o admirable_o frame_v engine_n consist_v of_o stable_a liquid_a and_o pneumatick_a substance_n so_o exquisite_o adapt_v to_o their_o respective_a function_n and_o use_v that_o oftentimes_o the_o effect_n of_o a_o agent_n upon_o it_o be_v not_o to_o be_v measure_v so_o much_o by_o the_o power_n of_o that_o agent_n consider_v in_o itself_o as_o by_o the_o effect_n that_o be_v
disorder_a nature_n may_v have_v in_o a_o disease_a body_n produce_v acid_n of_o several_a sort_n which_o be_v not_o particular_o know_v to_o we_o and_o that_o some_o of_o these_o may_v be_v of_o such_o a_o nature_n that_o none_o of_o our_o common_a alcaly_n as_o such_o be_v able_a to_o mortify_v they_o and_o which_o yet_o may_v be_v mortify_a at_o least_o by_o the_o way_n of_o shethe_v by_o some_o appropriate_v or_o peculiar_o modify_v corpuscle_n of_o a_o specific_a remedy_n which_o may_v be_v illustrate_v by_o what_o be_v elsewhere_o observe_v that_o tho'_o neither_o spirit_n of_o vinegar_n nor_o spirit_n of_o salt_n nor_o oil_n of_o vitriol_n itself_o will_v as_o far_o as_o i_o have_v try_v dissolve_v a_o stone_n take_v out_o of_o a_o man_n body_n yet_o spirit_n of_o niter_n which_o do_v not_o dissolve_v several_a podies_fw-mi that_o i_o have_v find_v dissoluble_a in_o oil_n of_o vitriol_n will_v ready_o work_v upon_o it_o and_o thereby_o lose_v its_o corrosiveness_n before_o i_o leave_v this_o subject_a it_o will_v not_o be_v amiss_o to_o intimare_fw-la a_o couple_n of_o thing_n that_o perhaps_o you_o will_v not_o think_v impertinent_a to_o it_o one_o of_o these_o be_v that_o whereas_o i_o not_o long_o ago_o distinct_o name_v acid_v themselves_o and_o their_o production_n i_o do_v it_o not_o out_o of_o inadvertence_n but_o because_o i_o think_v preternatural_a acid_n do_v not_o only_o disaffect_v the_o body_n while_o they_o continue_v sensible_o acid_n but_o may_v in_o divers_a case_n be_v the_o cause_n of_o some_o distemper_n whereof_o most_o man_n will_v think_v they_o more_o likely_a to_o be_v the_o remedy_n for_o tho'_o acid_n be_v repute_v to_o have_v a_o incisive_n and_o resolutive_a virtue_n and_o therefore_o oxymel_n and_o some_o other_o acetous_a medicine_n be_v commend_v to_o cut_v tough_a phlegm_n and_o spirit_n of_o vitriol_n be_v use_v for_o the_o same_o purpose_n and_o to_o dissolve_v coagulate_v blood_n yet_o as_o i_o be_o willing_a to_o grant_v this_o virtue_n unto_o acid_n in_o some_o case_n so_o there_o be_v other_o wherein_o i_o much_o suspect_v that_o obstruction_n and_o consequent_o the_o disease_n that_o usual_o attend_v obstinate_a one_o may_v be_v occasion_v by_o acid_n as_o they_o coagulate_v some_o fluid_n in_o the_o mass_n of_o blood_n that_o be_v dispose_v to_o be_v thicken_v by_o they_o and_o by_o that_o consistence_n make_v unfit_a to_o pass_v with_o the_o rest_n of_o the_o circulate_v blood_n through_o the_o small_a vessel_n and_o strainer_n of_o the_o body_n where_o upon_o that_o account_n they_o make_v obstruction_n this_o i_o shall_v exemplify_v by_o the_o coagulation_n that_o i_o have_v make_v by_o some_o acid_n salt_n as_o spirit_n of_o salt_n of_o the_o white_a of_o a_o egg_n especial_o if_o by_o beat_v reduce_v to_o a_o aqueous_a consistence_n and_o the_o like_a coagulation_n may_v easy_o be_v effect_v in_o milk_n which_o may_v not_o only_o be_v speedy_o curdle_v with_o spirit_n of_o salt_n but_o as_o be_v know_v by_o body_n not_o chemical_o prepare_v as_o rennet_n and_o juice_n of_o lemon_n and_o experiment_n purposely_o make_v have_v show_v that_o if_o some_o acid_n be_v convey_v immediate_o into_o the_o mass_n of_o blood_n they_o will_v coagulate_v even_o that_o liquor_n whilst_o it_o continue_v in_o the_o vessel_n of_o the_o yet_o live_a animal_n the_o other_o thing_n i_o late_o tell_v you_o i_o be_v to_o observe_v be_v that_o tho'_o acid_n corpuscle_n be_v those_o that_o modern_a physician_n and_o chemist_n be_v wont_a to_o take_v notice_n of_o as_o hurtful_a both_o in_o the_o blood_n and_o stable_a part_n of_o the_o body_n except_o the_o stomach_n and_o perhaps_o some_o few_o neighbour_a part_n as_o the_o spleen_n and_o pancre_n and_o tho'_o some_o ingenious_a man_n proceed_v so_o far_o as_o to_o impute_v almost_o all_o disease_n to_o the_o bad_a effect_n of_o acid_n yet_o i_o be_o very_o inclinable_a to_o think_v that_o divers_a malady_n and_o ttoublesom_a symptom_n proceed_v from_o corpuscle_n that_o whether_o they_o be_v of_o a_o saline_n nature_n or_o not_o be_v different_a from_o acid_n proper_o so_o call_v for_o i_o consider_v that_o there_o may_v be_v many_o body_n which_o may_v as_o it_o be_v result_n from_o the_o combination_n of_o acid_n with_o other_o saline_n particle_n that_o much_o alter_v their_o nature_n as_o i_o have_v elsewhere_o note_v that_o spirit_n of_o salt_n will_v with_o spirit_n of_o urine_n compose_v a_o kind_n of_o sal-armoniac_a and_o spirit_n of_o niter_n with_o salt_n of_o tartar_n dissolve_v in_o common_a water_n will_v concoagulate_v with_o it_o into_o salt_n petre_n or_o a_o body_n exceed_v like_o it_o and_o the_o same_o spirit_n of_o niter_n or_o aqua_fw-la fortis_fw-la with_o spirit_n of_o urine_n or_o of_o blood_n or_o the_o like_a will_v afford_v a_o very_a fusible_a salt_n differ_v enough_o from_o what_o either_o of_o the_o ingredient_n be_v before_o their_o conjunction_n and_o it_o be_v vulgar_o know_v that_o oil_n of_o vitriol_n and_o oil_n of_o tartar_n per_fw-la deliquium_fw-la do_v by_o their_o coalition_n produce_v tartarum_fw-la vitriolatum_fw-la in_o which_o the_o acidity_n of_o the_o former_a and_o the_o alcalisateness_n of_o the_o latter_a be_v very_o much_o infringe_v a_o three_o body_n be_v by_o resultancy_n produce_v that_o differ_v much_o both_o from_o the_o former_a and_o the_o latter_a oil_n or_o rather_o saline_n liquor_n and_o when_o beside_o instance_n of_o this_o nature_n i_o consider_v how_o many_o differ_a sort_n of_o corpuscle_n so_o fruitful_a a_o principle_n as_o nature_n may_v have_v form_v that_o without_o be_v acid_n may_v yet_o have_v notable_a and_o hurtful_a effect_n upon_o the_o blood_n or_o some_o particular_a solid_a part_n of_o the_o body_n it_o seem_v probable_a to_o i_o that_o there_o may_v be_v other_o quality_n require_v to_o mortify_v or_o disable_v these_o morbific_a corpuscle_n than_o a_o contrariety_n to_o acid_n salt_n and_o consequent_o that_o a_o medicine_n that_o afford_v corpuscle_n peculiar_o fit_v to_o correct_v or_o enervate_a this_o particular_a sort_n of_o hurtful_a one_o may_v deserve_v the_o name_n of_o a_o specific_a and_o here_o i_o further_o consider_v that_o as_o in_o the_o body_n there_o may_v be_v divers_a coagulation_n make_v by_o saline_n corpuscle_n manifest_o acid_n so_o there_o may_v be_v other_o produce_v by_o corpuscle_n whether_o saline_n in_o taste_n or_o no_o that_o be_v not_o manifest_o acid_n but_o perhaps_o rather_o of_o a_o contrary_a nature_n which_o observation_n be_v wont_a to_o be_v overlook_v by_o physician_n and_o yet_o in_o my_o opinion_n of_o no_o small_a importance_n may_v deserve_v to_o be_v a_o little_a the_o more_o careful_o make_v out_o i_o have_v sometime_o for_o curiosity_n make_v a_o liquor_n that_o be_v not_o in_o taste_n either_o acid_n or_o urinous_n to_o which_o have_v put_v a_o moderate_a proportion_n of_o a_o distil_a liquor_n which_o itself_o be_v not_o in_o taste_n either_o acid_n or_o urinous_a or_o lixiviate_v it_o will_v in_o a_o very_a short_a time_n perhaps_o in_o not_o many_o minute_n be_v coagulate_v into_o so_o consistent_a a_o body_n that_o tho'_o the_o wide_a mouth_a vessel_n be_v hold_v with_o the_o orifice_n downward_o nothing_o will_v fall_v out_o of_o it_o i_o have_v teach_v in_o another_o unpublished_a paper_n that_o if_o upon_o a_o certain_a solution_n which_o i_o there_o show_v how_o to_o make_v one_o drop_n some_o spirit_n of_o urine_n or_o anorhet_v volatile_a alcaly_a there_o will_v present_o be_v produce_v a_o jelly_n who_o consistence_n and_o colour_n may_v make_v it_o easy_o be_v take_v for_o common_a starch_n ready_a to_o be_v employ_v to_o stiffen_v linen_n the_o like_a jelly_n but_o more_o transparent_a i_o have_v more_o than_o once_o make_v without_o the_o help_n of_o any_o thing_n that_o be_v sensible_o acid_n or_o urinous_n i_o have_v also_o to_o convince_v some_o virtuoso_n show_v they_o somewhat_o to_o their_o surprise_n a_o substance_n i_o have_v prepare_v without_o the_o help_n of_o urine_n or_o any_o volatile_a alcaly_a and_o sometime_o almost_o in_o a_o trice_n that_o will_v in_o very_o few_o minute_n coagulate_v above_o twice_o if_o not_o thrice_o its_o weight_n of_o high_o rectify_v and_o inflammable_a vinous_a spirit_n into_o a_o stable_a mass_n and_o to_o show_v you_o that_o it_o be_v not_o requisite_a that_o a_o liquor_n be_v strong_o or_o so_o much_o as_o sensible_o acid_n to_o coagulate_v a_o animal_n substance_n as_o i_o late_o note_v that_o the_o spirit_n of_o salt_n do_v the_o white_a of_o a_o egg_n i_o shall_v add_v that_o well_o dephlegm_v spirit_n of_o wine_n will_v do_v the_o same_o thing_n as_o well_o if_o not_o better_o proposition_n iii_o sometime_o the_o specific_a medicine_n may_v help_v the_o patient_n by_o precipitate_v the_o peccant_a matter_n out_o of_o the_o blood_n or_o other_o liquor_n of_o the_o body_n
prefer_v before_o those_o pompous_a composition_n wherein_o man_n seem_v to_o have_v hope_v to_o surmount_v disease_n by_o the_o multitude_n of_o the_o ingredient_n upon_o the_o follow_a reason_n in_o all_o which_o i_o desire_v the_o advantage_n ascribe_v to_o simple_a medicine_n above_o other_o may_v be_v understand_v not_o in_o a_o absolute_a and_o indefinite_a sense_n but_o as_o they_o speak_v caeteris_fw-la paribus_fw-la which_o i_o here_o give_v you_o notice_n of_o once_o for_o all_o and_o the_o first_o advantage_n that_o i_o shall_v mention_v be_v that_o it_o be_v much_o less_o difficult_a to_o foresee_v the_o operation_n of_o a_o simple_a than_o of_o a_o very_a compound_a medicine_n so_o that_o physician_n may_v proceed_v more_o secure_o in_o employ_v the_o former_a than_o the_o latter_a sort_n of_o remedy_n and_o indeed_o if_o i_o do_v not_o great_o mistake_v we_o often_o presume_v too_o much_o of_o our_o own_o ability_n when_o we_o believe_v that_o we_o know_v before_o hand_n 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wary_o give_v in_o a_o just_a do_v do_v as_o far_o as_o i_o can_v yet_o learn_v seldom_o fail_v of_o work_v and_o yet_o seldomer_n work_n by_o salivation_n but_o by_o siege_n on_o the_o other_o side_n glass_n of_o antimony_n make_v per_fw-la se_fw-la whereof_o a_o very_a few_o grain_n give_v in_o substance_n be_v wont_a to_o work_v violent_o upward_o and_o downward_o be_v dissolve_v in_o spirit_n of_o vinegar_n which_o be_v not_o easy_o and_o quick_o do_v will_v not_o usual_o either_o vomit_n or_o purge_v though_o the_o menstruum_fw-la be_v draw_v from_o it_o and_o though_o it_o be_v give_v in_o a_o large_a dose_n than_o that_o of_o the_o uncompounded_a glass_n and_o though_o if_o crude_a antimony_n be_v flux_v with_o niter_n and_o tartar_n as_o in_o the_o ordinary_a way_n of_o make_v crocus_n metallorum_fw-la there_o be_v produce_v as_o be_v vulgar_o know_v a_o medicine_n so_o emetic_n and_o cathartick_n that_o a_o ounce_n or_o less_o of_o the_o wine_n wherein_o it_o have_v be_v 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have_v here_o the_o leisure_n instance_n enough_o may_v be_v bring_v to_o show_v that_o chemist_n sometime_o mistake_o produce_v by_o their_o addition_n to_o a_o medicine_n other_o quality_n if_o not_o also_o worse_o than_o they_o design_v or_o expect_v §_o ii_o another_o advantage_n of_o simple_a medicine_n be_v that_o caeteris_fw-la paribus_fw-la they_o be_v more_o safe_a than_o compound_a one_o especial_o if_o the_o patient_n be_v valetudinary_a person_n it_o be_v too_o much_o the_o custom_n both_o of_o many_o herbarist_n and_o several_a other_o writer_n on_o the_o materia_fw-la medica_fw-la to_o give_v we_o rather_o encomium_n than_o impartial_a account_n of_o the_o simple_n they_o treat_v of_o enumerate_v and_o magnify_v all_o the_o virtue_n they_o have_v and_o sometime_o more_o than_o they_o have_v without_o take_v notice_n of_o their_o ill_a quality_n upon_o who_o account_n nevertheless_o they_o may_v be_v inconvenient_a if_o not_o hurtful_a and_o dangerous_a to_o some_o constitution_n and_o in_o divers_a case_n we_o know_v that_o divers_a perfume_n as_o musk_n and_o amber_n though_o very_o grateful_a and_o refresh_a to_o most_o man_n spirit_n be_v yet_o very_o hurtful_a to_o many_o woman_n and_o especial_o to_o those_o that_o be_v hysterical_a and_o i_o have_v know_v the_o smell_n of_o musk_n very_o much_o disaffect_v a_o eminent_a person_n though_o otherwise_o of_o a_o robu_v constitution_n i_o have_v also_o know_v several_a person_n not_o all_o of_o they_o of_o the_o same_o sex_n very_o much_o offend_v by_o the_o smell_n of_o rose_n which_o yet_o be_v very_o moderate_a as_o well_o as_o to_o most_o person_n whether_o man_n or_o woman_n very_o grateful_a i_o know_v a_o very_a great_a person_n to_o who_o honey_n whether_o inward_o take_v or_o outward_o apply_v be_v almost_o as_o hurtful_a as_o poison_n have_v several_a time_n produce_v strange_a and_o frightful_a symptom_n even_o when_o the_o patient_n know_v not_o that_o any_o honey_n have_v be_v employ_v and_o consequent_o can_v not_o be_v thus_o odd_o distemper_v by_o the_o force_n of_o imagination_n i_o think_v i_o have_v elsewhere_o take_v notice_n of_o the_o harm_n that_o both_o i_o and_o other_o subject_a to_o disease_n of_o the_o eye_n have_v receive_v even_o by_o the_o moderate_a use_n of_o parsley_n on_o this_o occasion_n i_o shall_v add_v what_o occur_v to_o i_o long_o after_o i_o have_v dictate_v what_o i_o say_v of_o parsley_n that_o wormwood_n though_o for_o many_o use_n a_o excellent_a plant_n have_v be_v find_v by_o many_o so_o apt_a to_o disaffect_v the_o head_n and_o so_o unfriendly_a to_o the_o eye_n that_o i_o have_v for_o some_o year_n forbear_v it_o myself_o for_o fear_n of_o the_o headache_n and_o forewarn_v other_o of_o it_o that_o be_v subject_a to_o weak_a eye_n but_o i_o know_v a_o very_a learned_a man_n who_o elegant_a pen_n have_v make_v he_o deserve_o be_v take_a notice_n of_o by_o many_o
make_v the_o plantain_n or_o rose-water_n it_o be_v to_o be_v dissolve_v in_o considerable_o strong_a of_o it_o and_o for_o burns_n i_o have_v seldom_o see_v any_o thing_n equal_a to_o it_o and_o therefore_o have_v often_o use_v it_o upon_o myself_o bare_o dissolve_v in_o common_a or_o else_o plantain_n water_n but_o i_o fear_v it_o be_v not_o so_o safe_a as_o effectual_a in_o some_o inward_a distemper_n of_o the_o bowel_n that_o be_v judge_v to_o be_v cause_v by_o acid_n humour_n unless_o it_o be_v very_o wary_o and_o skilful_o give_v but_o as_o to_o its_o external_a use_n i_o presume_v i_o need_v not_o tell_v so_o skilful_a a_o doctor_n as_o you_o nb._n how_o great_a it_o be_v in_o heal_a and_o in_o the_o mean_a time_n appease_v the_o pain_n of_o divers_a sort_n of_o ulcer_n and_o therefore_o i_o shall_v mention_v but_o one_o particular_a which_o it_o be_v like_o you_o have_v not_o meet_v with_o namely_o that_o i_o know_v a_o very_a ancient_n and_o experience_a person_n who_o 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a_o person_n who_o though_o well_o furnish_v with_o choice_a remedy_n of_o his_o own_o often_o come_v to_o i_o for_o a_o supply_n of_o this_o spirituous_a and_o penetrate_a tincture_n with_o which_o he_o assure_v i_o he_o do_v notable_a thing_n in_o asthmatical_a case_n and_o particular_o in_o one_o that_o be_v very_o obstinate_a and_o have_v last_v many_o year_n but_o not_o have_v have_v quite_o so_o many_o opportunity_n as_o i_o wish_v of_o give_v it_o myself_o i_o shall_v be_v glad_a that_o further_a trial_n may_v be_v make_v of_o it_o by_o so_o skilful_a a_o administrer_fw-fr as_o you_o and_o therefore_o lest_o you_o shall_v not_o have_v the_o book_n late_o refer_v to_o at_o hand_n i_o shall_v here_o repeat_v that_o our_o medicine_n be_v make_v of_o flower_n of_o sulphur_n exact_o mix_v with_o a_o equal_a weight_n of_o fine_o powder_v sal-armoniac_a and_o somewhat_o more_o than_o a_o equal_a weight_n of_o good_a quicklime_n separately_z reduce_v to_o a_o suttle_n powder_n for_o these_o three_o ingredient_n be_v diligent_o and_o nimble_o mix_v and_o put_v into_o a_o retort_n to_o be_v place_v in_o a_o sand_n furnace_n and_o fit_v with_o a_o large_a receiver_n very_o well_o lute_v to_o it_o this_o mixture_n i_o say_v be_v due_o distil_v in_o such_o vessel_n will_v afford_v a_o blood_n red_a and_o smoke_a spirit_n exceed_v sulphureous_a both_o in_o smell_n and_o oven_n mechanical_a operation_n and_o in_o this_o distillation_n the_o sulphureous_a part_n sometime_o come_v over_o accompany_v with_o such_o store_n of_o saline_a one_o that_o a_o good_a part_n of_o what_o pass_v into_o the_o receiver_n shoot_v into_o the_o form_n of_o a_o volatile_a sulphureous_a salt_n and_o i_o remember_v that_o have_v for_o curiosity_n sake_n add_v to_o the_o fluid_a tincture_n a_o due_a proportion_n of_o a_o ardent_a spirit_n such_o as_o that_o of_o wine_n exact_o dephlegm_v i_o have_v a_o mixture_n whether_o in_o the_o form_n of_o a_o coagulum_fw-la or_o not_o which_o afford_v 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perceive_v that_o the_o particular_n above_o mention_v about_o simple_a preparation_n of_o gold_n and_o other_o metal_n have_v already_o make_v this_o section_n enormous_o great_a and_o yet_o i_o hope_v you_o will_v not_o be_v displease_v at_o it_o since_o to_o so_o sugacious_a a_o person_n as_o dr._n f._n these_o passage_n may_v afford_v some_o not_o altogether_o useless_a hint_n and_o at_o least_o it_o be_v a_o encouragement_n to_o industry_n to_o know_v that_o the_o subject_n a_o man_n work_v on_o be_v capable_a of_o afford_v excellent_a thing_n §._o vii_o 1._o i_o foresee_v it_o may_v be_v object_v against_o the_o frequent_a use_n of_o simple_a medicine_n that_o oftentimes_o it_o happen_v that_o a_o disease_n or_o a_o morbific_n matter_n be_v not_o the_o effect_n of_o a_o single_a cause_n but_o be_v produce_v by_o the_o concurrence_n of_o two_o or_o perhaps_o more_o cause_n which_o produce_v several_a symptom_n it_o be_v not_o probable_a that_o one_o simple_a drag_v will_v be_v able_a to_o answer_v those_o different_a indication_n this_o objection_n i_o confess_v be_v considerable_a &_o there_o be_v case_n wherein_o i_o acknowledge_v it_o to_o be_v so_o weighty_a as_o to_o invite_v &_o warrant_v a_o physician_n to_o employ_v in_o they_o a_o medicine_n consist_v of_o more_o ingredient_n than_o one_o or_o two_o which_o i_o can_v admit_v without_o prejudice_n to_o any_o design_n since_o i_o former_o declare_v i_o do_v not_o intend_v to_o persuade_v you_o to_o consine_n yourself_o to_o simple_a remedy_n so_o much_o as_o in_o the_o late_a sense_n above_o intimate_v of_o that_o term_n but_o only_a to_o employ_v they_o where_o they_o may_v suffice_v and_o where_o they_o can_v to_o make_v use_n of_o medicine_n as_o little_o compound_v as_o the_o case_n will_v permit_v 2._o but_o have_v premise_v this_o