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A41730 De succo pancreatico, or, A physical and anatomical treatise of the nature and office of the pancreatick juice shewing its generation in the body, what diseases arise by its vitiation : from whence in particular, by plain and familiar examples, is accurately demonstrated, the causes and cures of agues, or intermitting feavers, hitherto so difficult and uncertain, with sundry other things of worthy note / written by D. Reg. de Graaf ... ; and translated by Christopher Pack ...; Tractatus anatomico-medicus de succi pancreatici natura & usu. English Graaf, Reinier de, 1641-1673.; Packe, Christopher, fl. 1670-1711. 1676 (1676) Wing G1463; ESTC R17762 82,340 198

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would be performed with greater success if to the mixture even now described you shall add a drop or two of Oyl of Cloves because as yet we see no medicament that doth more powerfully take away Cold than that Oyle If a great Heat follow the feaverish Cold to attemper that Medicines called Refrigeraters among which aqueous things diluting the Bile seems to us most agreeable but especially Acids with which the acrimony and volatillity of the saline Bile exceeding producing Heat and burning is best infringed For as Doctor Minrotus saith pag. 36. in his Treatise of Malignant Feavers Acids do repress the inflamabillity of a Sulphurous Matter without the Body so also within the Body they bridle the inflaming Bile So Hippocrates De Victu Acutor Text. 29. 9. manifestly Teacheth that Acids do infringe and mitigate the Bile And this is the Reason why the most skilfullest Physitians do daily prescribe Acid Julips for the temperating of that feverish Heat as for Example by the Decoction of Barley or coolling distilled Waters with Syrup of Limmons Mulberies or Barberies c. By adding Spirit of Vitriol Oyl of Sulpher per Capanum or other Acid Spirits in a sufficient quantity to give it a grateful Acidity For the same end they also sometimes prescribe Apozems of the opening Roots the Herb Sorrel Lettice the greater Housleek Tamarinds c. by adding after the boyling some Acid Syrrups and an acid Spirit sufficient for a grateful Acidity that the sick may now and then take a small Draught thereof to temperate the Heat If a great Thirst afflict the Feaverish at the time of Heat half a Dram of Lap. Prunella may be conveniently dissolved in the aforesaid Apozeme or in small Ale or in a convenient Julip for it excellently extinguisheth Thirst and therefore those to whom Drink is hurtful may dissolve the same Medicament in Water but in a greater quantity to wash the Mouth Here it is well to be noted that at the time of the Heat it is not necessary that the Sick should abstain from moderate Drinking which at the time of Cold is altogether required because we daily see that if Drink be assumed at the time of the Cold fit that it is augmented and the Sick more troubled If the Medicaments even now mentioned for Example do not take away the Feaver in the Intervals wherein they are not vexed with the Feaver this following mixture will much avail R. Fennel Water three Ounces Simple Treacle Water six Drams distilled Vinegar three Drams Crabs Eyes prepared half a Dram Syrup of the five opening Roots half an Ounce mixt Of which most simple mixture let one spoonful be taken every two houres for altering Medicines do operate far better if they be taken by Intervals then if they be taken abundantly together and at once If vehement Paines and Watchings do accompany the Feaver Mixtures are to be used in the Intervals to which is added one Grain of Laudanum Opiatum which Medicament we do believe hath also a force of temperating the accimony of the Humours because we see that Paines arising from the Acrimony of Humours remain not after Sleep procured by the prudent assumption of Laudanum Opiat which in our Opinion could not happen if that Laudanum had not a force of temperating sharp Humours If a pain of the Head accompany the Feaver in stead of fennel water that of bettony or burrage may be substituted and in place of the Syrup of the five Roots Syrup of Diacodium or white Poppies But if the Stomach be evilly affected Water of Mint or of Carduus Benedictus will be used with better success If the menses flow not Water of Peniroyal Syrup of Mugwort c. may be exhibited If a suffocation of the Womb be present in stead of those may be added Spirit of Sal Ammoniack Tinct of Castor c. if the Sick be tormented with flatulencies Spirit of Nitre may be added which remedy doth greatly help those which are troubled with a collick Passion or any other flatulent Diseases especially if some Drops thereof be prudently mixed with some Arromatick Waters and the aforesaid Carminatives If the Appetite be prostrate by Reason of too great a quantity of Bile carried to the Stomach which will be known by the Appetite suddenly Destroyed by bitter Belchings and Cholerick Vomitings two Scruples of Elixir Proprietatis Paracelsi may be added to the last mixture But if the said evil proceedeth from a vicid pituity detained in the Stomach which will be known by an aggravated pain in the Stomach half a Dram of the dulcid Spirit of Salt instead of Elixir Proprietatis will be more Conducent if it be mixed with the foresaid mixture To the same intent may be directed also divers Apozemes and other medicate Wines Powders Pills and medicaments against the said Obstructions Nevertheless you must diligently diligently Note that Apozemes and other Medicaments especially refrigerating which promiscuously they daily compel the Sick to swallow down in a great Dose sometimes so debillitate their Stomacks that the Appetite is thereby not only Destroyed but sometimes fall into a disdain or Loathing of Aliments from whence a new Affliction is added to the Sick and the latter Errour is allso very often worse than the first But if notwithstanding before the Physician hath attained his desired end he thinketh some other Humour doth offend by too much plenty that may be diminished with convenient medicines The Diet according to the diversity of intermitting Feavers must sometimes be changed because Tertian Feavers accompanied with the greatest Heat do require a Diet more Cooling than Quartans which very often afflict the Sick with intollerable Cold and Trembling For we see the moderate use of French Wine which we are wont to forbid in all Tertians somtimes to be granted in Quartans But such a Diet as may be agreeable to all intermitting Feavers every one may gather from what we have already spoken We would have further propounded some other Remedies as well accomodated to intermitting Feavers as to their Symptomes had not the most Famous Doctor Sylvius in the first Part of his Praxis already Printed proposed many and the most excellent of them From my Study Feb. 2d 167 5 6. at the Signe of the Globe and Chymical Furnaces in the Postern near Moor-Gate London FINIS POST-SCRIPT I Have taken notice of many People especially of the Poorer sort who are afflicted with tedious Agues and many more who labour under those Deplorable Fits commonly called the Fits of the Mother and Spleen as also the Falling Sickness Grievous Convulsions c. And being well satisfied as well by the means of Curation as the undenyable Experiments and valid Reasons in this Book confirming the same that those Diseases with many more derive their Original from the Vitious Alteration of this Juyce of the Sweet-Bread I for the sake of poor People that they might have help at an easie Rate hereby let them know that amongst many other I have
with a sence of Cold and terminated with heat For the Pancreatick Juice being made more sharp by stagnation in one or more of the lateral Ducts after which flowing into the thin Gut there exciteth such an effervescency with the Bile wherein the Succus Pancreaticus by its predominant Acidity every way emits or sends forth acid Exhalations affected with a sense of Cold which when they touch the Gall-bladder by their acrimony provoke it to its Contraction from whence the Bile breaking forth into the Intestine in a more than usual quantity overwhelmes the Pancreatick Juice and raiseth therewith such an Effervescency in which the Bile predominating Excites heat by sending every way its exhalations or Emissaries This our Opinion is in a wonderful manner confirmed by the Vomitings which very often happen to the Sick at one time so cold and Acid that bringeth a stupor to the Teeth and again on the contrary another while so hot and bitter that they believe they Vomit nothing but pure Choler But some perhaps may ask why we deduce Vomitings and acid belchings rather from the Pancreas than from the Stomach We answer because it is agreeable to experience that the Pancreatick Juice is Acid and seeing that the searchers of Nature do as yet dispute concerning the ferment of the Stomach and its Generation we judged that it ought to be determined rather from a certain than an uncertain Cause And if it shall be evinced by further search in the stomach of Men we speak not of Birds who require a stronger fermentation to digest Stones and other things of a hard consistency for the Generation of Shells that any other ferment is generated besides the Spittle continually swallowed and that to be Acid then shall we be so much the better able to prove an Effervescency to be excited in the thin Gut between the Bile and the Pancreatick Juice Seeing that the Temperate or Natural Acidity of the Pancreatick Juyce would be helped by the acid Ferment of the Stomach and from thence the Effervescency would be the more powerfully performed It is further proved that the Acidity cast forth by Vomitting doth not proceed from the Stomach but from the Intestines by Vomitories exhibited out of the time of the Fit by the help whereof first an insipid Matter afterwards by further straining an Acid and Bilious Matter is vomitted up the contrary of which would happen if the Soure and Cholerick Matter did proceed from the Stomach Concerning the manner by which Acids may get to the Stomach no man of a sound mind will doubt who determines the Bile ejected by Vomiting to proceed from the Intestines Seeing that the Pancreatick Juyce may and ought to be driven through the same wayes as the Bile flowing to the Intestines by their inverted Peristaltick Motion with the same ease to the Ventricle as we have above demonstrated Neither doth the place a little confirm this our Opinion in which a Feaverish fit beginning is for the most part perceived Cold then Hot as also a most fierce pain We understand the Region of the Loynes in which the first part of the thin Gut lies under the Mesentery as is to be seen Tab. I wherein the Confsux and Effervescency of the Bile and the Pancreatick Juyce is Celebrated from which the Particles of those Humours being agitated upon the Ligaments of the Mesentery and other Nervous and Membranous parts they dash against them with an Impetuous force So that that Effervescency may sometimes be perceived by the Touch in the Sick as we have above demonstrated Nor does the Pancreatick Juyce being made sharp by stagnation only exercise a tyranny in the Region of the Loynes but also sends forth its acid Exhalations both upwards and downwards Who doubteth that from the one the Torments of the Belly and from the other Acid belchings do proceed But if those Exhalations penetrate through the Venae Lacteae to the Heart by Incrassating the Blood gives an occasion of a lesser Pulse which nevertheless by its corroding Acrimony produceth one more frequent The Acid Exhalations being subdued in manner afore-said Salt and Bilious Exhalations do follow which again by attenuating the Blood do no less excite a great and sometimes also a more frequent Pulse by irritating the Heart and that so long till their Acrimony being spent they can no longer irritate or provoke the Heart Which done the Vigour and Natural pulse of the Heart is returned So that very often the most skilful can hardly judge whether they have a Feaver or no. We will not here speak lest this Chapter should swell too much with that which we purposed to finish in few Words concerning six Hundred other Symptomes which are wont to accompany Intermitting Feavers seeing we are perswaded there are none at least of those who with an attent mind have considered that the Juyce or its Emissaries after a diverse manner disposed doth perambulate the whole Body and may produce diverse Symptomes but may from these things deduce them by their own proper Industry Which seeing it is so we leaving those small Circumstances shall rightly pass on to the Cure of intermitting Feavers which as it Primarily consisteth in taking away Obstructions and correcting the Pancreatick Juice and other Humours if they be Vitious so it may be most succesfully performed first by Medicines inciding and attenuating tough Phlegme and sometimes expelling it from the Body Secondly By adhibiting Remedies which are indued with a force of correcting and temperating the Pancreatick Juice offending by its Acrimony Thirdly By correcting other Humours in the Body this or that way so peccant that they may Cherish the Vicious Effervescency excited in the thin Gut between the Bile and the Pancreatick Juice For the taking away the Obstruction temperating the more acid Pancreatick Juyce and the diminishing the Cold from thence proceeding these following Medicines do much conduce viz. Water of Parsly Fennel Baume Simple treacle-Treacle-Water Salt of Worm-wood of Centary the lesser Syrup of Carduus Benedicttus or the five opening Roots and the like being mixed according to Art especially if taken halfe an hour before the feaverish Cold invades the Sick who ought to be kept in his bed or other warm place that Sweat may be a little promoted or at leastwise that the operation of the Medicine may not be hindered We say half an hour before the feaverish Cold invade the Sick because Reason teacheth and Experience proveth that cutting and attenuating as unobstructing Medicaments do then with a far more happy Success absolve that for which they are Administred than if they were exhibited at any other time the Reason of which seemes to us because those Medicines begin to operate at that time wherein the Pancreatick Juice by its Acrimony doth molifie the Obstruction and so by a united force may more strongly and more happily dissolve the Obstruction than if either of those only were opperating Moreover It very much diminisheth the Feaverish Cold which as yet