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A41730 De succo pancreatico, or, A physical and anatomical treatise of the nature and office of the pancreatick juice shewing its generation in the body, what diseases arise by its vitiation : from whence in particular, by plain and familiar examples, is accurately demonstrated, the causes and cures of agues, or intermitting feavers, hitherto so difficult and uncertain, with sundry other things of worthy note / written by D. Reg. de Graaf ... ; and translated by Christopher Pack ...; Tractatus anatomico-medicus de succi pancreatici natura & usu. English Graaf, Reinier de, 1641-1673.; Packe, Christopher, fl. 1670-1711. 1676 (1676) Wing G1463; ESTC R17762 82,340 198

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plain_o ridiculous_a to_o be_v willing_a to_o see_v the_o effervescency_n of_o those_o humour_n and_o to_o impede_fw-la the_o humour_n by_o which_o they_o be_v perform_v or_o not_o to_o admit_v of_o the_o preturnal_a constitution_n of_o the_o animal_n and_o willing_a to_o see_v those_o thing_n which_o be_v perform_v in_o the_o bowel_n of_o animal_n if_o their_o pancreatic_a juice_n who_o desire_v this_o thing_n be_v endue_v with_o such_o a_o acrimony_n as_o nevertheless_o be_v destitute_a of_o natural_a help_n may_v ferment_n with_o the_o bile_n to_o the_o eye_n without_o the_o body_n with_o how_o great_a pain_n will_v not_o their_o bowel_n be_v torment_v if_o be_v help_v by_o those_o aid_n in_o the_o body_n the_o effervescency_n shall_v be_v perform_v doubtless_o they_o will_v not_o desire_v such_o a_o aciditie_n before_o they_o will_v subscribe_v to_o our_o so_o often_o commemorate_a fermentation_n but_o in_o short_a will_v wish_v for_o themselves_o such_o a_o pancreatic_a juice_n as_o we_o have_v above_o deem_v to_o raise_v up_o therein_o a_o natural_a effervescency_n last_o the_o three_o difficulty_n which_o have_v be_v propose_v to_o we_o against_o the_o effervescency_n between_o the_o bile_n and_o the_o pancreatic_a juice_n be_v that_o the_o pancreatic_a juice_n be_v acid_o salt_n as_o it_o be_v ordinary_o find_v in_o dog_n ought_v not_o to_o ferment_n with_o the_o bile_n see_v that_o the_o acidite_fw-mi thereof_o by_o reason_n of_o the_o salt_n therein_o contain_v help_v the_o innervate_v liquor_n will_v be_v subdue_v but_o we_o may_v easy_o answer_v this_o objection_n also_o by_o distinguish_a sea-salt_n fossile-salt_n and_o other_o compound_v of_o a_o lixiviate-salt_n and_o acid-spirit_n from_o the_o pure_a lixiviate_v salt_n no_o man_n will_v ever_o deny_v but_o that_o the_o last_o of_o acid_n do_v lose_v its_o force_n and_o energy_n and_o consequent_o hinder_v its_o effervescency_n but_o that_o which_o appertain_v to_o the_o first_o of_o who_o nature_n we_o esteem_v that_o
of_o any_o other_o thing_n with_o the_o blood_n then_o volatile_a salt_n but_o on_o the_o contrary_a if_o you_o mingle_v any_o acid_a spirit_n with_o the_o blood_n dictum_fw-la factum_fw-la the_o blood_n will_v be_v more_o or_o less_o coagulate_v according_a as_o that_o spirit_n shall_v be_v more_o or_o less_o acid_n as_o for_o example_n if_o to_o try_v the_o experiment_n we_o take_v oil_n of_o vitriol_n oil_n of_o sulphur_n per_fw-la campanum_n aqua_fw-la fortis_fw-la aqua_fw-la regius_fw-la etc._n etc._n beside_o that_o the_o blood_n will_v present_o be_v coagulate_v by_o they_o it_o also_o acquire_v a_o chestnut_n colour_n but_o if_o we_o take_v the_o dulcet_a spirit_n of_o salt_n juice_n of_o lammons_n distil_v vinegar_n or_o the_o like_a who_o acid_a spirit_n be_v more_o temperate_a the_o blood_n will_v only_o acquire_v the_o consistency_n of_o a_o grosser_n syrup_n with_o its_o red_a colour_n remain_v unhurt_a from_o whence_o it_o be_v evident_a the_o use_n of_o acid_n may_v preserve_v man_n from_o the_o plague_n not_o as_o according_a to_o the_o opinion_n of_o many_o author_n that_o they_o cut_v and_o attenuate_v but_o as_o they_o preserve_v the_o natural_a consistency_n of_o the_o blood_n and_o do_v hinder_v its_o be_v infect_v with_o a_o more_o sharp_a volatile_a salt_n which_o we_o together_o with_o the_o air_n suck_v into_o our_o body_n for_o this_o cause_n the_o most_o famous_a dr._n silvius_n who_o likewise_o have_v constitute_v the_o venom_n of_o the_o plague_n in_o a_o more_o sharp_a volatile_a salt_n when_o some_o year_n since_o in_o the_o great_a plague_n at_o amsterdam_n which_o he_o foresee_v he_o take_v a_o crust_n of_o bread_n imbrue_v with_o white-wine-vinegar_n in_o which_o mary-gold_n have_v likewise_o be_v steep_v by_o which_o alexipharmack_n he_o so_o well_o preserve_v himself_o that_o he_o never_o be_v infect_v with_o the_o pestilential_a venom_n but_o when_o through_o too_o much_o haste_n he_o omit_v the_o say_a alexipharmack_n as_o soon_o as_o he_o enter_v into_o a_o infect_a house_n he_o be_v infect_v with_o a_o pain_n in_o the_o head_n from_o which_o at_o other_o time_n he_o be_v free_a which_o thing_n be_v right_o consider_v every_o one_o may_v see_v that_o the_o pestilent_a venom_n be_v not_o endue_v with_o any_o force_n of_o coagulate_v as_o the_o most_o learned_a willis_n have_v state_v it_o in_o his_o treatise_n of_o fever_n c._n 13._o but_o see_v that_o dr._n dela-font_n have_v sufficient_o clear_v this_o to_o all_o opposer_n in_o his_o discourse_n concern_v the_o pestilent_a venom_n chap._n viii_o we_o shall_v not_o spend_v any_o more_o time_n either_o to_o the_o reader_n or_o ourselves_o but_o wave_v the_o further_a disquisition_n of_o those_o thing_n because_o it_o be_v beside_o our_o purpose_n in_o this_o treatise_n accurate_o to_o describe_v the_o pestilence_n wherefore_o we_o will_v leave_v the_o rest_n to_o a_o further_a occasion_n see_v it_o be_v time_n that_o we_o return_v to_o the_o incommodity_n flow_v from_o the_o more_o acid_n pancreatic_a juice_n the_o pancreatic_a juice_n be_v more_o sharp_a be_v the_o cause_n first_o of_o every_o internal_a cold_a be_v first_o of_o all_o feel_v in_o the_o region_n of_o the_o loin_n and_o afterward_o disperse_v into_o the_o whole_a body_n as_o for_o the_o most_o part_n we_o observe_v in_o the_o begin_n of_o the_o fit_v of_o ague_n or_o intermit_a fever_n second_o of_o all_o cut_v pain_n as_o well_o in_o the_o hypocondria_n and_o whole_a belly_n as_o in_o other_o part_n of_o the_o body_n three_o of_o all_o manifest_a pain_n in_o the_o belly_n from_o whence_o the_o sick_a be_v sometime_o torment_v after_o a_o wonderful_a manner_n wherefore_o we_o deduce_v all_o the_o black_a and_o aeruginous_a bile_n from_o the_o same_o more_o acid_n pancreatic_a juice_n because_o sometime_o be_v put_v into_o a_o pewter_n chamber_n pot_n or_o brass_n bason_n they_o corrode_v the_o same_o and_o send_v forth_o a_o sharp_a savour_n and_o also_o excite_v a_o manifest_a effervescency_n which_o every_o man_n who_o have_v salute_v but_o the_o threshold_n of_o chemistry_n know_v can_v happen_v from_o any_o thing_n but_o acid_n from_o whence_o they_o may_v be_v compel_v to_o confess_v their_o error_n who_o affirm_v that_o all_o black_a choler_n proceed_v from_o vomit_v or_o dejection_n of_o the_o belly_n come_v from_o the_o follicles_n of_o the_o gall_n or_o the_o spleen_n all_o these_o thing_n be_v not_o a_o little_a confirm_v by_o the_o follow_a experiment_n sometime_o make_v by_o we_o in_o a_o dog_n in_o the_o section_n of_o who_o be_v alive_a have_v open_v the_o duodenum_fw-la we_o find_v a_o greenish_a liquor_n among_o the_o black_a such_o as_o the_o ancient_n have_v depict_v to_o we_o for_o atrabilis_fw-la that_o we_o may_v pursue_v a_o more_o intimate_v cognition_n thereof_o we_o examine_v diligent_o all_o the_o way_n through_o which_o any_o thing_n may_v be_v transfer_v to_o that_o intestine_a and_o see_v that_o beside_o the_o bilar_a dust_n the_o pancreatic_a and_o the_o ventrile_a there_o be_v no_o way_n perceptible_a to_o the_o sight_n through_o which_o any_o notable_a quantity_n of_o humour_n may_v be_v afford_v to_o the_o intestine_n we_o judge_v therefore_o that_o in_o one_o of_o those_o the_o matter_n thereof_o must_v be_v obscure_v wherefore_o we_o examine_v all_o those_o way_n in_o the_o first_o whereof_o we_o find_v the_o bile_n natural_o constitute_v that_o wax_a yellow_a from_o a_o green_a in_o the_o second_o we_o find_v the_o pancreatic_a juice_n most_o limpid_a like_a to_o distil_v water_n in_o the_o three_o we_o find_v the_o aliment_n half_o crude_a have_v the_o colour_n of_o white_a ash_n see_v therefore_o that_o neither_o the_o liver_n nor_o the_o pancreas_n nor_o also_o the_o stomach_n carry_v that_o atrabilis_fw-la to_o the_o intestine_a we_o begin_v to_o suspect_v whether_o that_o atrabilis_fw-la may_v not_o emerge_n by_o the_o union_n of_o two_o or_o three_o of_o those_o humour_n be_v mingle_v together_o by_o course_n concern_v which_o thing_n that_o we_o may_v attain_v to_o a_o great_a certainty_n we_o affused_a spirit_n of_o vitriol_n to_o the_o bile_n draw_v forth_o from_o its_o vesicle_n and_o place_v it_o in_o the_o heat_n of_o the_o sun_n from_o whence_o there_o be_v common_o excite_v from_o the_o black_a a_o greenish_a liquor_n such_o as_o we_o first_o find_v in_o the_o duodenum_fw-la hence_o we_o conclude_v the_o say_a humour_n call_v atrabilis_fw-la not_o to_o flow_v from_o this_o or_o that_o part_n but_o to_o be_v generate_v in_o the_o duodenum_fw-la namely_o as_o the_o natural_a colour_n of_o the_o bile_n have_v be_v transmit_v into_o black_a and_o green_a by_o the_o concourse_n of_o the_o more_o acid_n pancreatic_a juice_n see_v that_o the_o pancreatic_a juice_n by_o the_o ordinary_a law_n of_o nature_n may_v continual_o be_v mingle_v with_o the_o bile_n and_o the_o intestinal_a pituity_n we_o will_v a_o little_a propose_v the_o same_o as_o join_v with_o those_o humour_n if_o it_o chance_v that_o the_o more_o sluggish_a pancreatic_a juice_n bound_n with_o a_o sharp_a bile_n and_o the_o intestinal_a pituity_n right_o constitute_v the_o strength_n of_o the_o pancreatic_a juice_n in_o that_o concourse_n will_v be_v altogether_o infringe_v and_o the_o exhalation_n which_o be_v excite_v by_o the_o effervescency_n of_o those_o humour_n will_v ascend_v not_o so_o much_o with_o acid_n as_o lixivious_a particle_n which_o when_o they_o reach_v to_o the_o stomach_n by_o infringe_v its_o fermentation_n they_o will_v hinder_v the_o concoction_n of_o the_o aliment_n and_o destroy_v the_o appetite_n but_o if_o it_o happen_v that_o those_o exhalation_n ascend_v to_o the_o jaw_n there_o among_o other_o incommodity_n they_o will_v induce_v a_o dryness_n of_o the_o mouth_n especial_o if_o they_o infect_v the_o hospital_n with_o their_o salsitude_n but_o if_o they_o proceed_v further_o through_o the_o milky_a vein_n to_o the_o heart_n from_o whence_o with_o the_o blood_n they_o may_v pass_v through_o the_o other_o part_n of_o the_o body_n they_o will_v also_o produce_v a_o heat_n in_o those_o as_o at_o first_o in_o the_o intestine_n and_o there_o more_o troublesome_a where_o those_o exhalation_n be_v most_o sharp_a if_o a_o more_o sharp_a pancreatic_a juice_n concur_v with_o a_o sharp_a bile_n there_o will_v present_o be_v a_o mighty_a effervescency_n excite_v in_o the_o duodenum_fw-la whereby_o the_o intestine_n be_v sometime_o so_o distend_v that_o they_o threaten_v a_o ruption_n which_o thing_n we_o have_v very_o often_o observe_v whilst_o we_o apply_v ourselves_o to_o our_o study_n in_o leyden_n whilst_o we_o mix_v together_o divers_a liquor_n sit_v for_o fermentation_n in_o two_o little_a vessel_n in_o part_n of_o the_o intestine_a intercept_v by_o ligature_n even_o as_o d._n schuyl_n have_v express_v it_o fig._n b._n in_o his_o treatise_n de_fw-fr veteri_fw-la medicina_fw-la wherefore_o we_o judge_v in_o the_o first_o instant_a
more_o acid_a pancreatic_a juice_n because_o they_o more_o often_o occur_v and_o produce_v great_a trouble_n than_o those_o which_o derive_v their_o original_a from_o this_o juice_n by_o any_o other_o way_n vitiate_v for_o the_o acid_a humour_n excel_v the_o rest_n witness_v hippoc._n lib._n de_fw-la vet._n med._n text._n 42._o 14._o of_o all_o other_o be_v the_o most_o incommodious_a chap._n x._o how_o the_o vitiate_a pancreatic_a juice_n may_v be_v correct_v see_v that_o it_o be_v not_o sufficient_a to_o have_v say_v in_o what_o manner_n the_o pancreatic_a juice_n may_v offend_v namely_o by_o exercise_v too_o great_a a_o acidity_n salsitude_n and_o amaritude_n we_o have_v not_o restore_v it_o say_v hippocrates_n before_o that_o the_o same_o be_v purge_v and_o overthrow_v by_o the_o admix_v of_o other_o thing_n lib._n de_fw-fr vet_n med._n text_n 34._o but_o with_o what_o medicament_n the_o vice_n of_o the_o pancreatic_a juice_n above_o declare_v may_v more_o easy_o be_v temper_v or_o evacuate_v we_o shall_v now_o handle_v in_o brief_a the_o more_o spare_a separation_n or_o excretion_n of_o the_o pancreatic_a juice_n happen_v by_o reason_n of_o viscidity_n will_v be_v cure_v by_o medicine_n correct_v any_o viscidity_n such_o be_v volatile_a acid_n as_o also_o salt_n as_o well_o volatile_a as_o fix_v especial_o the_o volatile_a salt_n of_o amber_n seem_v to_o agree_v with_o our_o business_n which_o beside_o the_o volatile_a salt_n also_o contain_v certain_a acid_n particle_n but_o as_o often_o as_o the_o pancreatic_a juice_n be_v think_v to_o be_v less_o acid_a then_o use_v pure_a acid_n on_o the_o contrary_a as_o often_o as_o the_o acidity_n thereof_o exceed_v than_o salt_n be_v most_o conducible_a when_o the_o excretion_n of_o the_o pancreatic_a juice_n be_v more_o spare_v by_o reason_n of_o a_o obstruction_n happen_v in_o one_o or_o more_o of_o the_o lateral_a duct_n the_o medicine_n but_o now_o speak_v of_o be_v also_o profitable_a for_o except_o they_o loosen_v cleanse_v and_o cast_v forth_o the_o obstruct_v pituity_n or_o remedy_n the_o viscous_a crudity_n of_o the_o blood_n they_o will_v certain_o profit_v nothing_o as_o we_o shall_v endeavour_v more_o large_o to_o explain_v the_o same_o in_o the_o subsequent_a chapter_n when_o we_o shall_v treat_v of_o intermit_a fever_n the_o more_o copious_a increase_n of_o the_o pancreatic_a juice_n will_v be_v cure_a as_o well_o by_o abstain_v from_o much_o drink_n especial_o such_o as_o be_v sharp_a also_o by_o use_v such_o medicament_n as_o may_v expel_v it_o from_o the_o body_n by_o the_o belly_n as_o also_o sweat_v and_o urine_n but_o among_o such_o medicament_n as_o educe_v it_o by_o the_o belly_n such_o as_o purge-water_n be_v convenient_a above_o other_o by_o help_n whereof_o the_o serous_a humour_n be_v purge_v more_o than_o the_o bilious_a which_o some_o year_n since_o we_o have_v observe_v in_o not_o a_o few_o dog_n to_o who_o we_o exhibit_v as_o well_o hydragogue_n as_o cholague_n and_o see_v that_o they_o excellent_o depone_v the_o belly_n we_o sudden_o open_v the_o abdomen_fw-la at_o the_o very_a time_n of_o purgation_n the_o dog_n be_v as_o yet_o live_v which_o do_v we_o can_v observe_v although_o difficulty_n in_o those_o to_o who_o we_o have_v give_v a_o cholagogue_n viz._n one_o dram_n of_o diagredium_fw-la that_o the_o bile_n do_v flow_v in_o a_o far_o great_a quantity_n from_o the_o intestinal_n biliar_a dust_n but_o in_o another_o to_o who_o we_o have_v exhibit_v a_o hydragogue_n namely_o of_o powder_n of_o jallap_v two_o dram_fw-la we_o observe_v that_o the_o pancreatic_a juice_n do_v break_v forth_o in_o a_o large_a quantity_n from_o its_o ductus_fw-la into_o the_o intestine_n although_o then_o the_o bile_n also_o do_v issue_n forth_o in_o a_o great_a quantity_n and_o in_o another_o to_o who_o we_o have_v give_v a_o cholagogue_n the_o pancreatic_a juice_n do_v also_o flow_v forth_o in_o a_o great_a quantity_n than_o usual_a nevertheless_o we_o be_v able_a to_o collect_v that_o the_o bile_n be_v far_o more_o copious_o purge_v by_o cholagogue_n and_o the_o pancreatic_a juice_n by_o hydragogue_n in_o these_o experiment_n perform_v other_o thing_n do_v yet_o occur_v worthy_a of_o note_n for_o first_o of_o all_o at_o the_o very_a time_n of_o purgation_n there_o be_v nothing_o deposit_v through_o the_o meseraick_n artery_n into_o the_o cavity_n of_o the_o intestine_n but_o what_o so_o ever_o of_o a_o liquid_a matter_n remain_v in_o they_o after_o expression_n be_v suck_v up_o by_o the_o venae_fw-la lacteae_fw-la or_o meseraick_n vein_n second_o that_o those_o duct_n in_o who_o the_o lactean_a vein_n appear_v not_o after_o 3._o or_o 4._o hour_n exhibition_n of_o aliment_n we_o cut_v the_o abdomen_fw-la in_o they_o neither_o the_o bile_n nor_o the_o pancreatic_a juice_n be_v carry_v to_o the_o intestine_a in_o a_o more_o than_o usual_a quantity_n concern_v which_o see_v that_o other_o thing_n as_o yet_o remain_v to_o be_v speak_v to_o we_o shall_v defer_v it_o to_o another_o occasion_n until_o by_o many_o experiment_n more_o sure_o make_v we_o shall_v more_o perfect_o also_o understand_v the_o force_n of_o other_o medicament_n the_o pancreatic_a juice_n over_o fluid_a will_v be_v correct_v by_o the_o prudent_a assumption_n of_o viscid_a aliment_n such_o be_v pill_n of_o hound_n tongue_n and_o other_o thing_n which_o incrassate_fw-it in_o reference_n to_o the_o quality_n of_o the_o pancreatic_a juice_n perceptible_a to_o the_o taste_n if_o it_o offend_v by_o too_o much_o acidity_n austerity_n or_o salsity_n it_o will_v be_v cure_v first_o with_o alter_v medicine_n as_o hypocrates_n have_v right_o teach_v we_o de_fw-fr vet._n med._n tex_n 31._o 20._o where_o he_o say_v and_o i_o perceive_v all_o other_o flux_n which_o happen_v by_o reason_n of_o the_o acrimony_n and_o intemperances_n of_o humour_n be_v restore_v by_o their_o temper_n and_o coct_v but_o that_o will_v easy_o be_v absolve_v by_o the_o administration_n of_o the_o medicine_n even_o now_o speak_v of_o the_o more_o acid_n pancreatic_a juice_n will_v be_v cure_v first_o with_o a_o pure_a volatile_a salt_n as_o a_o aromatic_a by_o temper_v the_o same_o second_o it_o will_v be_v cure_v with_o a_o lixivious_a salt_n as_o well_o fix_v as_o volatile_a by_o infringe_v its_o power_n three_o it_o will_v be_v cure_v by_o crab_n eye_n coral_n chalk_n shell_n especial_o be_v calcine_v fileing_n of_o steel_n and_o the_o like_a by_o concentrate_v it_o four_o it_o will_v be_v cure_v by_o oleous_a emulsion_n as_o also_o by_o diverse_a oil_n make_v as_o well_o by_o expression_n as_o distillation_n as_o it_o be_v wrap_v about_o it_o and_o blunt_v the_o edge_n thereof_o i_o know_v not_o how_o to_o render_v obvoluo_n and_o obtundo_n better_a five_o it_o will_v be_v cure_v with_o water_n &_o watery_a thing_n wash_v and_o weaken_v it_o but_o here_o no_o purge_n be_v to_o be_v exhibit_v because_o hitherto_o none_o be_v know_v which_o without_o great_a difficulty_n do_v educe_v the_o acid_n humour_n not_o temper_v so_o that_o aphorism_n of_o hippoc._n 22._o sect._n 11._o which_o say_v thing_n coct_v not_o crude_a be_v bring_v forth_o by_o a_o purge_v medicine_n be_v not_o crude_a in_o their_o beginning_n unless_o they_o swell_v but_o many_o do_v not_o swell_v do_v right_o here_o take_v place_n the_o austere_a pancreatic_a juice_n will_v be_v cure_v by_o volatile_a salt_n as_o first_o by_o the_o distil_v spirit_n of_o salt_n ammoniac_a after_o the_o addition_n of_o salt_n of_o tartar_n and_o water_n to_o which_o also_o may_v be_v refer_v castor_n and_o its_o tincture_n the_o salt_n pancreatic_a juice_n and_o a_o diarhaea_n from_o thence_o arise_v may_v be_v cure_v by_o the_o diascordium_n of_o fracastorius_fw-la pill_n of_o hound_n tongue_n coral_n burn_a hart's-horn_n bezoar-stone_n and_o other_o thing_n incrassate_v and_o also_o concentrate_v salsitude_n chap._n xi_o the_o history_n of_o ague_n or_o intermit_a fever_n because_o we_o have_v before_o promise_v in_o the_o nine_o chapter_n that_o we_o will_v in_o this_o place_n demonstrate_v that_o intermit_a fever_n have_v their_o original_a from_o the_o preternatural_a disposition_n of_o the_o say_v pancreatic_a juice_n we_o can_v but_o annex_v their_o history_n not_o because_o the_o difficulty_n of_o explicate_v these_o fever_n be_v obscure_a to_o we_o nor_o shun_v none_o of_o the_o most_o expert_a physician_n so_o as_o hitherto_a they_o have_v not_o satisfy_v the_o curious_a in_o their_o explication_n so_o that_o be_v by_o most_o pass_v over_o with_o a_o dry_a foot_n they_o have_v leave_v behind_o they_o a_o series_n of_o innumerable_a difficulty_n but_o because_o we_o judge_v it_o to_o be_v a_o thing_n of_o so_o great_a moment_n that_o as_o many_o as_o hitherto_a have_v give_v themselves_o to_o the_o search_n of_o intermit_a fever_n have_v still_o desire_v to_o this_o labour_n the_o further_a industry_n of_o other_o learned_a man_n