spoon_n and_o cause_n no_o more_o effect_n than_o oil_n of_o olive_n and_o spirit_n of_o sal_fw-la amenoniack_a take_v inward_o one_o act_v too_o soft_o lazy_o and_o greasy_o to_o cause_v any_o brisk_a and_o agreeable_a ovation_n of_o the_o spirit_n and_o the_o other_o too_o rude_o sting_v the_o membrane_n therefore_o we_o must_v proceed_v in_o our_o enquiry_n four_o opium_n have_v a_o sort_n of_o resinous_n sulphur_n that_o be_v loose_a and_o not_o unite_v with_o the_o volatile_a salt_n which_o plain_o appear_v 1._o because_o if_o you_o dissolve_v opium_n in_o water_n cold_a or_o hot_a or_o any_o watery_a menstruum_fw-la you_o will_v find_v a_o good_a quantity_n of_o rosin_n undissolved_a at_o bottom_n while_o the_o volatile_a salt_n be_v all_o or_o most_o dissolve_v in_o the_o water_n especial_o if_o the_o water_n be_v often_o repeat_v and_o quite_o separate_v from_o the_o resinous_n part_v which_o subside_v without_o any_o more_o trouble_n which_o show_v that_o the_o volatile_a salt_n and_o it_o be_v not_o combine_v but_o in_o a_o very_a loose_a and_o distinct_a manner_n 2._o because_o if_o you_o first_o dissolve_v opium_n in_o spirit_n of_o wine_n which_o imbibe_v the_o rosin_n it_o be_v easy_o again_o precipitate_v by_o plain_a water_n leave_v behind_o it_o all_o or_o most_o of_o the_o volatile_a salt_n in_o the_o form_n of_o a_o red_a tincture_n in_o the_o menstruum_fw-la as_o it_o do_v also_o in_o the_o former_a case_n note_v that_o the_o resinous_n part_n of_o opium_n have_v no_o effect_n as_o a_o opiate_n for_o if_o it_o be_v well_o wash_v with_o water_n as_o be_v say_v it_o have_v no_o operation_n of_o that_o kind_n or_o so_o little_a that_o it_o be_v not_o worth_a the_o mind_v but_o all_o the_o virtue_n specific_a taste_n smell_v etc._n etc._n be_v carry_v away_o in_o that_o red_a tincture_n which_o have_v all_o the_o good_a effect_n of_o opium_n as_o experience_n assure_v we_o 3._o because_o if_o opium_n be_v very_o much_o torrefy_v most_o of_o the_o volatile_a salt_n be_v evaporate_v and_o with_o it_o most_o if_o not_o all_o the_o virtue_n of_o opium_n but_o the_o rosin_n remain_v as_o a_o deadish_a stuff_n in_o respect_n of_o the_o good_a effect_n of_o opium_n though_o it_o be_v as_o shall_v be_v prove_v the_o producer_n of_o the_o ill_a effect_n thereof_o therefore_o this_o rosin_n must_v be_v whole_o reject_v five_o the_o red_a tincture_n aforesaid_a have_v all_o or_o most_o of_o the_o volatile_a salt_n in_o it_o 1._o because_o water_n be_v the_o proper_a menstruum_fw-la for_o saline_n thing_n and_o that_o the_o tincture_n reduce_v to_o a_o extract_n give_v very_o much_o in_o moist_a wether_n which_o quality_n it_o must_v have_v from_o the_o volatile_a salt_n because_o it_o have_v very_o little_o fix_v salt_n 2._o because_o the_o specific_a bitterness_n which_o proceed_v from_o volatile_a salt_n and_o oily_a part_n be_v whole_o in_o that_o red_a tincture_n 3._o because_o that_o tincture_n have_v also_o the_o specific_a rankness_n of_o smell_n that_o the_o volatile_a salt_n as_o be_v show_v give_v the_o opium_n by_o the_o help_n of_o some_o oily_a part_n 4._o because_o that_o tincture_n reduce_v to_o a_o extract_n have_v the_o bite_a taste_n of_o opium_n which_o as_o be_v show_v proceed_v from_o its_o volatile_a salt_n 5._o because_o that_o extract_n incides_fw-la discuss_n resolve_n be_v psilothrick_n titillate_n to_o venery_n cause_v itch_n in_o the_o skin_n acrimonious_a sweat_v etc._n etc._n all_o which_o be_v as_o be_v show_v the_o effect_n of_o volatile_a salt_n but_o what_o need_v i_o insist_v so_o much_o upon_o its_o effect_n to_o prove_v it_o when_o 6._o it_o appear_v by_o crystalization_n of_o the_o say_a tincture_n after_o it_o have_v be_v evaporate_v to_o a_o due_a degree_n that_o it_o contain_v the_o volatile_a salt_n in_o it_o which_o in_o a_o cool_a place_n shoot_v to_o elegant_a crystal_n and_o that_o 7._o it_o be_v find_v therein_o by_o chemical_a operation_n by_o fire_n six_o the_o say_a tincture_n be_v oleose_v 1._o because_o the_o redness_n of_o the_o tincture_n must_v be_v from_o oily_a part_n for_o pure_a sincere_a volatile_a salt_n give_v no_o such_o tincture_n 2._o because_o it_o be_v bitter_a one_o ingredient_n of_o which_o taste_n be_v ever_o oily_a part_n as_o be_v say_v 3._o because_o of_o its_o rank_a smell_n like_o sem._n viril_n which_o prove_v it_o to_o be_v sulphureous_a for_o the_o volatile_a salt_n alone_o have_v only_o a_o quick_a smell_n or_o urinous_a at_o far_a 4._o because_o it_o be_v of_o a_o hot_a taste_n when_o reduce_v to_o a_o extract_n which_o heat_v of_o taste_n consider_v distinct_o from_o its_o pungent_a or_o bite_a taste_n must_v be_v from_o sulphureous_a or_o oily_a part_n 5._o because_o spirit_n of_o wine_n and_o other_o spirituosulphureous_a menstruum_n do_v ready_o dissolve_v it_o when_o reduce_v to_o a_o extract_n 6._o because_o the_o extract_n soften_v with_o dry_a warmth_n as_o sulphureous_a or_o oily_a thing_n do_v 7._o because_o a_o true_a sal-volatile-oleosum_a wherein_o the_o volatile_a salt_n and_o oily_a part_n be_v intimate_o combine_v as_o you_o find_v in_o all_o blood_n tincture_n of_o several_a plant_n that_o have_v such_o a_o sal-volatile-oleosum_a be_v red_a 8._o because_o it_o can_v not_o otherwise_o so_o fine_o please_v the_o membrane_n cause_n sleep_n compose_v the_o spirit_n etc._n etc._n if_o it_o be_v all_o volatile_a salt_n which_o be_v whole_o pungent_a and_o acrimonious_a mighty_o oppose_v sleep_n and_o cause_v a_o great_a stir_n in_o the_o blood_n and_o spirit_n but_o as_o i_o say_v as_o to_o its_o volatile_a salt_n what_o need_v i_o insist_v upon_o its_o effect_n when_o 10._o it_o be_v inflammability_n after_o it_o be_v reduce_v to_o a_o extract_n and_o dry_v put_v it_o out_o of_o all_o question_n and_o that_o 11._o a_o oil_n may_v be_v separate_v from_o the_o volatile_a salt_n though_o not_o without_o trouble_n because_o that_o as_o be_v requisite_a to_o complete_a it_o in_o the_o high_a degree_n seven_o the_o oily_a part_n and_o volatile_a salt_n be_v very_o intimate_o and_o strict_o combine_v as_o fair_o appear_v 1._o by_o the_o difficulty_n to_o separate_v they_o 2._o by_o the_o redness_n of_o the_o tincture_n as_o in_o blood_n etc._n etc._n for_o when_o oily_a or_o sulphureous_a particle_n be_v loose_a therein_o they_o make_v either_o a_o white_a colour_n as_o the_o rosin_n do_v in_o the_o drop_n that_o fall_v out_o of_o the_o incision_n in_o the_o head_n of_o the_o poppy_n which_o be_v milk_n white_a or_o leave_v the_o volatile_a spirit_n perspicuous_a as_o in_o a_o sort_n of_o artificial_a sal._n volatile-oleosum_a that_o be_v sell_v at_o the_o apothecary_n shop_n in_o london_n 3._o because_o it_o impart_v its_o tincture_n which_o depend_v upon_o both_o to_o all_o menstruum_n 4._o because_o it_o impart_v its_o virtue_n which_o depend_v upon_o both_o to_o all_o menstruum_n 5._o because_o it_o impart_v its_o specific_a smell_n which_o depend_v upon_o both_o to_o all_o menstruumt_v 6._o because_o it_o impart_v its_o specific_a hot_a and_o bite_a taste_n which_o depend_v upon_o both_o the_o oily_a and_o volatile_a particle_n to_o all_o menstruum_n 7._o because_o it_o will_v hold_v its_o virtue_n many_o year_n which_o it_o can_v not_o if_o the_o volatile_a salt_n and_o oily_a part_n be_v not_o very_o strict_o combine_v 8._o because_o that_o notwithstanding_o the_o digestion_n at_o stomach_n it_o have_v hold_v its_o specific_a virtue_n smell_v and_o taste_n after_o it_o have_v be_v in_o it_o 4_o 5_o 6_o 7_o 8_o 9_o 10_o 11_o 12_o 18_o or_o more_o hour_n as_o appear_v by_o its_o operate_n so_o long_o and_o afteward_n its_o be_v vomit_v up_o with_o the_o same_o taste_n and_o smell_v that_o it_o have_v at_o first_o than_o which_o there_o can_v be_v a_o great_a argument_n 9_o because_o it_o have_v be_v carry_v off_o by_o stool_n which_o have_v its_o specific_a smell_n after_o many_o hour_n remain_v in_o the_o stomach_n 10._o because_o its_o operation_n in_o general_n last_v long_o charas_fw-la mention_n one_o that_o it_o operate_v with_o for_o about_o 30_o hour_n and_o wedelius_n another_o who_o opium_n cause_v to_o vomit_v constant_o about_o 18_o hour_n after_o it_o be_v take_v 11._o because_o it_o have_v its_o effect_n upon_o the_o venereal_a membrane_n after_o it_o have_v pass_v the_o digestion_n at_o stomach_n the_o effect_n of_o the_o choler_n and_o succus_fw-la pancreatus_fw-la in_o the_o duodenum_fw-la be_v strain_v through_o the_o coat_n of_o the_o intestine_n into_o the_o lacteal_v and_o through_o the_o glandule_n of_o the_o mesentery_n mix_v and_o circulate_v with_o the_o blood_n etc._n etc._n 12._o because_o after_o all_o that_o it_o have_v its_o effect_n upon_o the_o skin_n by_o cause_v a_o itch_a therein_o 13._o because_o it_o not_o only_a cause_n acrimonious_a sweat_v but_o such_o as_o evident_o smell_v thereof_o
etc._n as_o wine_n hot_a liquor_n and_o opium_n do_v 12._o opium_n do_v very_o much_o open_v the_o pore_n and_o cause_n perspiration_n etc._n etc._n which_o only_a heat_n as_o that_o in_o bath_n bagnio_n hot_a house_n and_o hot_a thing_n do_v but_o cold_a shut_v the_o pore_n as_o all_o know_v therefore_o 13._o opium_n cure_v and_o prevent_v cold_n which_o be_v another_o argument_n of_o its_o heat_n 14._o it_o be_v a_o great_a aphrodisiack_a or_o exciter_n to_o venery_n which_o cold_a thing_n chill_a but_o hot_a thing_n as_o cantharides_n bee_n pismire_n onion_n garlic_n leek_n rocket_n squill_n horse_n radish_n sem._n human._n etc._n etc._n do_v promote_v 15._o nothing_o cause_v indolence_n give_v internal_o but_o wine_n hot_a liquor_n etc._n etc._n as_o i_o can_v think_v of_o and_o opium_n cause_v it_o much_o after_o the_o same_o manner_n as_o wine_n do_v first_o cause_v mirth_n and_o jollity_n and_o upon_o increase_n of_o quantity_n very_o considerable_a indolence_n it_o be_v true_a that_o cold_a will_v external_o cause_v a_o stupor_n if_o it_o be_v intense_a so_o as_o to_o constringe_v the_o part_n and_o exclude_v the_o spirit_n but_o otherwise_o it_o make_v the_o feel_v more_o nice_a as_o all_o know_v by_o experience_n because_o every_o little_a hurt_n affect_v we_o more_o when_o we_o be_v cold_a than_o hot_a but_o this_o be_v not_o the_o case_n of_o relax_a opium_n which_o be_v use_v internal_o to_o take_v away_o pain_n as_o wine_n etc._n etc._n 16._o nothing_o take_v away_o the_o effect_n of_o opium_n or_o drunkeness_n better_o than_o cold_a thing_n internal_o and_o external_o as_o acid_n dip_v in_o cold_a water_n etc._n etc._n 17._o opium_n relax_n all_o part_n which_o heat_n do_v and_o cold_a constringe_n as_o be_v intimate_v 18._o wedelius_n confess_v though_o it_o make_v against_o what_o he_o say_v that_o he_o never_o observe_v a_o soporose_n distemper_n where_o there_o be_v not_o a_o preternatural_a heat_n opiolog_fw-la lib._n 1._o sect._n 1_o cap._n 12._o p._n 46._o 19_o if_o it_o cause_v sleep_n by_o its_o cold_a quality_n than_o all_o thing_n that_o be_v cold_a will_v do_v it_o proportionable_o cucumber_n purslane_n etc._n etc._n will_v be_v so_o great_a hypnotick_n that_o we_o shall_v not_o be_v able_a to_o eat_v a_o drachm_n of_o they_o but_o that_o they_o will_v cause_v a_o great_a sopor_fw-la but_o there_o be_v no_o such_o thing_n and_o hot_a thing_n be_v much_o more_o apt_a to_o cause_v sleep_n or_o a_o sopor_fw-la as_o wine_n hot_a spirit_n onion_n garlic_n and_o such_o like_a 20._o opium_n cause_v a_o redness_n or_o efflorescence_n of_o the_o skin_n make_v it_o sensible_o warm_a as_o heat_n wine_n and_o strong_a liquor_n do_v 21._o it_o cause_v also_o a_o itch_a of_o the_o skin_n which_o only_o hot_a thing_n do_v 22._o half_n a_o drachm_n of_o opium_n in_o clyster_n have_v cause_v a_o violent_a heat_n in_o the_o gut_n 23._o it_o stop_v diarrheas_n or_o looseness_n which_o cold_a cause_n 24._o it_o stop_v defluxion_n cough_n etc._n etc._n which_o cold_a cause_n 25._o to_o pin_v up_o all_o its_o predominant_a principle_n appear_v by_o autopsie_n upon_o its_o chemical_a analysis_n to_o be_v volatile_a salt_n and_o sulphur_n beside_o this_o opinion_n of_o the_o coldness_n of_o opium_n be_v very_o much_o explode_v and_o indeed_o it_o be_v so_o apparent_o false_a and_o absurd_a that_o i_o shall_v not_o have_v think_v it_o worth_a while_n to_o argue_v against_o it_o but_o that_o it_o lay_v so_o in_o my_o way_n that_o regular_o i_o can_v not_o well_o avoid_v it_o without_o breach_n of_o order_n and_o method_n i_o may_v have_v add_v that_o it_o resolve_v attenuate_v etc._n etc._n but_o it_o be_v needless_a to_o say_v any_o more_o it_o be_v very_o false_a and_o erroneous_a that_o it_o stop_v flux_n by_o incrassate_v and_o bind_v which_o be_v account_v cold_a quality_n if_o so_o how_o shall_v it_o stop_v they_o when_o pound_n of_o incrassative_n and_o binder_n have_v fail_v though_o the_o opium_n be_v give_v only_o in_o the_o quantity_n of_o a_o grain_n or_o two_o how_o shall_v it_o stop_v or_o moderate_a flux_n even_o while_o it_o be_v yet_o at_o stomach_n as_o it_o most_o certain_o do_v it_o bear_v as_o etmuller_n well_o observe_v no_o proportion_n to_o the_o blood_n and_o humour_n to_o have_v any_o effect_n that_o may_v be_v remarkable_a upon_o they_o for_o a_o grain_n be_v but_o as_o 1_o to_o 115200_o to_o the_o blood_n of_o he_o that_o have_v 20_o pound_n of_o blood_n which_o a_o ordinary_a man_n have_v beside_o how_o can_v altenuative_n resolver_n and_o discusser_n incrassate_fw-it or_o bind_z but_o more_o especial_o how_o can_v so_o great_a a_o relaxer_n of_o part_n be_v a_o constringer_n thereof_o that_o be_v perfect_a contradiction_n and_o how_o can_v a_o mere_a sal_fw-la volatile_a oleosum_fw-la in_o which_o all_o its_o virtue_n lie_v as_o will_v plain_o appear_v thicken_v and_o bind_v the_o truth_n be_v that_o it_o stop_v flux_n as_o sleep_n do_v by_o take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o solicit_v the_o part_n to_o contract_n and_o so_o to_o extrude_v and_o squeeze_v they_o out_o it_o promote_v perspiration_n by_o relax_v the_o pore_n as_o sleep_n do_v it_o also_o seem_v to_o thicken_v rheum_n as_o sleep_n do_v because_o it_o cause_v sleep_n or_o at_o least_o take_v away_o a_o sense_n of_o the_o irritation_n of_o the_o rheum_n be_v thereby_o suffer_v to_o stay_v till_o it_o thicken_v by_o the_o heat_n of_o the_o body_n the_o irritation_n also_o at_o windpipe_n be_v less_o because_o the_o flux_n of_o the_o rheum_n be_v moderate_v for_o the_o reason_n aforesaid_a but_o of_o these_o thing_n more_o full_o when_o we_o come_v to_o explain_v the_o cause_n or_o cause_n of_o the_o effect_n of_o opium_n chap._n x._o it_o be_v prove_v that_o opium_n send_v no_o fume_n etc._n etc._n from_o the_o stomach_n to_o the_o head_n brain_n etc._n etc._n and_o therefore_o that_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n etc._n etc._n by_o that_o mean_n though_o the_o opinion_n of_o the_o cold_a of_o opium_n be_v much_o explode_v that_o of_o fume_n vapour_n or_o aura_n arise_v from_o the_o opium_n at_o stomach_n and_o mount_v up_o to_o the_o brain_n etc._n etc._n be_v as_o much_o receive_v and_o embrace_v i_o know_v none_o but_o such_o as_o think_v it_o absolute_o necessary_a consider_v that_o it_o be_v most_o certain_a and_o allow_v by_o all_o observe_a man_n that_o opium_n produce_v all_o or_o most_o of_o its_o effect_n while_o it_o be_v at_o stomach_n that_o the_o genus_fw-la neruâ—sum_fw-la be_v most_o concern_v in_o its_o operation_n and_o that_o as_o be_v say_v there_o be_v no_o operation_n or_o action_n but_o by_o contact_n so_o that_o the_o modern_n acquiesce_v in_o the_o necessity_n of_o its_o operate_n that_o way_n because_o they_o can_v conceive_v no_o other_o which_o be_v no_o proof_n but_o a_o defect_n of_o their_o conception_n look_v upon_o it_o as_o invincible_a and_o uncontrollable_a evidence_n oâ—_n its_o operate_n by_o detachment_n of_o fume_n or_o 〈◊〉_d send_v up_o to_o the_o brain_n from_o the_o stomach_n which_o appear_v so_o undeniable_o conclusive_a that_o neither_o the_o want_n of_o a_o sensible_a passage_n nor_o any_o other_o inconvenience_n signify_v any_o thing_n with_o they_o to_o the_o contrary_a therefore_o it_o become_v a_o establish_a foundation_n by_o common_a consent_n only_o they_o differ_v as_o be_v show_v in_o the_o manner_n how_o those_o fume_n produce_v the_o effect_n of_o opium_n and_o well_o they_o may_v see_v there_o be_v no_o such_o thing_n nor_o possibility_n if_o they_o be_v of_o ever_o explicate_v the_o various_a effect_n of_o opium_n by_o that_o mean_n as_o will_v manifest_o appear_v i_o confess_v that_o if_o opium_n operate_v by_o such_o fume_n pass_v from_o the_o stomach_n to_o the_o brain_n etc._n etc._n it_o will_v be_v easy_a to_o conceive_v how_o it_o shall_v diminish_v or_o disable_v nay_o utter_o ruin_v the_o animal_n spirit_n and_o indeed_o impossible_a rational_o to_o conceive_v how_o they_o can_v do_v otherwise_o but_o then_o the_o enliven_a invigorate_n and_o encourage_v effect_n of_o opium_n which_o be_v its_o constant_a and_o most_o genuine_a off_o spring_n will_v lie_v upon_o our_o hand_n without_o any_o possibility_n of_o give_v a_o account_n thereof_o for_o certain_o dull_a heavy_a unnatural_a undigested_a and_o cloudy_a fume_n or_o vapour_n can_v not_o advantage_v the_o animal_n spirit_n cause_v a_o triumph_n or_o ovation_n thereof_o at_o their_o access_n courage_n serenity_n promptitude_n magnanimity_n euphory_n inclination_n to_o venery_n etc._n etc._n which_o we_o be_v most_o oblige_v to_o regard_n as_o be_v its_o most_o natural_a and_o proper_a effect_n this_o opinion_n of_o the_o modern_n do_v presume_v or_o suppose_v for_o they_o prove_v nothing_o first_o that_o fume_n
by_o squeeze_v in_o some_o case_n and_o stop_v it_o by_o shut_v the_o pore_n in_o other_o case_n 10._o it_o be_v by_o it_o that_o contraction_n that_o fear_v cold_a etc._n etc._n close_v the_o pore_n and_o repel_v the_o blood_n staunch_a bleed_a so_o happen_v also_o a_o great_a contraction_n of_o the_o pupil_n of_o the_o eye_n by_o the_o same_o cause_n 11._o it_o be_v the_o violence_n of_o this_o contraction_n upon_o fear_n terror_n pain_n cold_a etc._n etc._n close_v the_o small_a vessel_n of_o the_o animal_n spirit_n and_o thereby_o repel_v they_o cause_v the_o shiver_a in_o those_o case_n by_o the_o renitency_n of_o the_o elastic_a animal_n spirit_n spring_v back_o again_o toties_fw-la quoties_fw-la have_v gain_v more_o elastic_a force_n by_o the_o very_a compression_n itself_o which_o that_o contraction_n cause_n so_o that_o by_o reason_n of_o the_o dubious_a velitation_n or_o skirmish_v between_o the_o repel_v contraction_n and_o the_o spring_a spirit_n happen_v a_o tremulous_a motion_n as_o of_o quaver_v spring_n which_o shiver_a in_o ague-fits_a do_v former_o lead_v i_o to_o the_o situation_n of_o the_o cause_n of_o ague_n when_o i_o write_v my_o book_n de_fw-fr febribus_fw-la intermittentibus_fw-la in_o the_o angustiae_fw-la at_o the_o end_n of_o the_o vessel_n which_o terminate_v in_o the_o membrane_n the_o grievous_a sensation_n of_o which_o cause_v all_o the_o shiver_a that_o happen_v in_o any_o case_n to_o animal_n 12._o by_o the_o same_o contraction_n when_o very_o violent_a and_o of_o the_o whole_a body_n cold_a sweat_v happen_v in_o pain_n fear_v terror_n etc._n etc._n while_o it_o violent_o squeeze_v out_o the_o outmost_a and_o therefore_o cold_a moisture_n of_o our_o body_n as_o laundress_n do_v water_n out_o of_o wet_a linen_n by_o contortion_n thus_o if_o you_o dip_v one_o half_a of_o a_o wet_a cold_a sheet_n in_o hot_a water_n wrap_v the_o hot_a side_n within_o the_o cold_a or_o let_v a_o warm_a sheet_n that_o be_v contort_a cool_a on_o the_o outside_n of_o it_o and_o then_o wring_v it_o as_o woman_n do_v linen_n the_o water_n that_o first_o exudate_n will_v be_v cold_a for_o in_o this_o case_n the_o close_n of_o the_o pore_n avail_v nothing_o to_o hinder_v it_o as_o long_o as_o the_o express_a force_n master_n it_o more_o especial_o in_o animal_n body_n wherein_o the_o part_n be_v so_o contrive_v that_o humour_n design_v for_o exoretion_n can_v well_o return_v and_o therefore_o must_v upon_o contraction_n run_v out_o hence_o it_o be_v that_o alum_n or_o vitriol_n which_o be_v very_o astringent_a and_o therefore_o close_a the_o pore_n will_v notwithstanding_o cause_v the_o mouth_n or_o nose_n to_o run_v very_o plentiful_o with_o moisture_n by_o contract_v all_o the_o membrane_n about_o the_o mouth_n or_o nose_n and_o thereby_o squeeze_v out_o the_o moisture_n design_v to_o be_v excern_v which_o can_v return_v because_o the_o part_n be_v contrive_v against_o the_o return_n or_o readmittance_n thereof_o whereas_o alum_n or_o vitriol_n will_v staunch_v or_o stop_v blood_n by_o the_o same_o contraction_n because_o it_o may_v return_v as_o not_o be_v design_v to_o be_v excern_v either_o into_o the_o artery_n and_o so_o pass_v by_o other_o branch_n thereof_o or_o which_o be_v more_o ready_a and_o natural_a keep_v its_o course_n into_o the_o vein_n so_o the_o two_o riddle_n that_o i_o have_v know_v some_o proud_a physician_n amaze_v at_o though_o but_o trifle_n of_o alum_n and_o vitriol_n cause_v the_o spital_n etc._n etc._n to_o come_v out_o instead_o of_o stop_v it_o by_o their_o astringency_n and_o their_o stop_a blood_n at_o nose_n at_o the_o same_o time_n they_o cause_v the_o snot_n or_o other_o humour_n to_o run_v out_o be_v unfold_v 13._o it_o be_v by_o this_o mighty_a contraction_n grow_v to_o a_o enormous_a degree_n that_o the_o animal_n spirit_n be_v violent_o compress_v grow_v exceed_o irrequiete_a as_o upon_o convulsion_n in_o great_a pain_n or_o very_o grievous_a sensation_n at_o stomach_n etc._n etc._n while_o the_o sensitive_a soul_n compress_v they_o with_o mighty_a force_n and_o somewhat_o disorderly_a and_o uneven_o because_o of_o the_o confusion_n and_o hurry_n he_o be_v in_o to_o relieve_v the_o animal_n they_o by_o their_o springiness_n fling_v up_o and_o down_o with_o great_a vigour_n this_o make_v convulsive_a motion_n have_v great_a strength_n 14._o the_o body_n under_o this_o contraction_n be_v manifest_o shrink_v by_o measure_n especial_o when_o the_o sensation_n be_v very_o grievous_a but_o most_o of_o all_o if_o they_o cause_v a_o general_a convulsion_n which_o i_o manifest_o observe_v in_o a_o little_a bitch_n that_o be_v convulsive_a all_o over_o for_o three_o hour_n and_o be_v just_a expire_n when_o i_o give_v she_o the_o sal_fw-la volat._n oleo_n of_o opium_n which_o perfect_o restore_v she_o by_o relax_v the_o vessel_n some_o may_v think_v it_o strange_a that_o nature_n shall_v contrive_v a_o more_o nice_a and_o smart_a sensation_n which_o the_o contraction_n of_o the_o vessel_n of_o the_o animal_n spirit_n must_v cause_v by_o compress_v they_o etc._n etc._n in_o pain_n and_o by_o it_o which_o become_v so_o much_o the_o more_o acute_a whereas_o one_o will_v judge_v that_o nature_n will_v rather_o contrive_v its_o ease_n than_o improve_v its_o smart_n you_o be_v to_o know_v that_o the_o pain_n be_v in_o order_n to_o relieve_v the_o animal_n by_o exciting_a all_o its_o power_n to_o defend_v expel_v or_o reject_v the_o cause_n and_o that_o without_o a_o grievous_a sensation_n the_o sensitive_a soul_n be_v neither_o mind_v nor_o excite_v to_o do_v it_o and_o the_o more_o the_o pain_n be_v the_o more_o it_o be_v stir_v up_o to_o self-preservation_n and_o as_o be_v show_v the_o more_o vigorous_a do_v its_o motion_n grow_v by_o the_o compression_n of_o the_o elastic_a spirit_n to_o perform_v that_o work_n so_o nature_n not_o regard_v the_o pain_n which_o be_v rather_o for_o good_a as_o much_o as_o take_v away_o the_o cause_n advance_v that_o for_o this_o purpose_n like_o a_o wise_a physician_n who_o find_v a_o grievance_n at_o stomach_n not_o sufficient_a to_o excite_v effectual_a vomit_v to_o throw_v away_o the_o grieve_v cause_n add_v to_o the_o grievance_n by_o give_v a_o vomit_n which_o because_o as_o be_v say_v nature_n be_v proportionable_o excite_v to_o and_o invigorate_v for_o self-preservation_n sufficient_o solicit_v and_o enable_v it_o by_o a_o strong_a contraction_n to_o reject_v the_o grieve_v matter_n as_o the_o great_a the_o relaxation_n be_v the_o more_o be_v the_o rest_n of_o all_o part_n and_o the_o weak_a the_o animal_n spirit_n because_o less_o compress_v the_o gentle_a be_v all_o motion_n as_o you_o see_v in_o sleep_n consequent_o the_o less_o be_v the_o expense_n of_o spirit_n so_o that_o in_o sleep_n we_o generate_v more_o than_o we_o spend_v and_o be_v thereby_o recruit_v so_o the_o more_o the_o contraction_n be_v the_o more_o violent_a be_v the_o motion_n of_o the_o heart_n intestine_n and_o of_o all_o part_n and_o consequent_o the_o expense_n of_o spirit_n be_v the_o great_a therefore_o it_o can_v be_v no_o wonder_n that_o contraction_n do_v cause_n great_a commotion_n of_o spirit_n diary_n fever_n etc._n etc._n when_o you_o consider_v 1._o that_o the_o sensitive_a soul_n be_v by_o the_o grievous_a sensation_n etc._n etc._n that_o cause_n they_o put_v upon_o a_o great_a fret_v concern_v and_o hurry_v to_o defend_v the_o animal_n and_o lay_v about_o he_o all_o manner_n of_o way_n for_o self-preservation_n 2._o that_o the_o animal_n spirit_n be_v by_o mean_n of_o great_a compression_n cause_v by_o the_o defensive_a contraction_n in_o a_o very_a forcible_a springiness_n which_o cause_v all_o the_o action_n that_o be_v continual_a involuntary_a and_o of_o course_n to_o be_v perform_v with_o great_a violence_n proportionable_a to_o its_o compress_a elasticity_n beside_o that_o 3._o the_o systole_n of_o the_o heart_n be_v oftener_o repeat_v all_o which_o conspire_v to_o cause_v great_a commotion_n upon_o grievous_a sensation_n whereby_o diary_n fever_n etc._n etc._n be_v cause_v which_o be_v easy_o and_o natural_o cure_v by_o sleep_n or_o relaxation_n at_o present_a compose_v and_o quiet_v those_o perturbation_n who_o know_v though_o it_o be_v not_o my_o business_n to_o discuss_v it_o at_o present_a but_o that_o the_o contraction_n in_o the_o cold_a fit_n of_o ague_n have_v a_o great_a hand_n in_o cause_v the_o hot_a one_o how_o otherwise_o shall_v opium_n by_o only_o take_v away_o the_o grievous_a sensation_n of_o the_o cold_a fit_n take_v off_o or_o prevent_v the_o hot_a fit_n also_o but_o of_o this_o in_o my_o often-mentioned_n tract_n though_o not_o so_o often_o as_o it_o grieve_v i_o that_o it_o be_v not_o publish_v how_o reasonable_o may_v we_o now_o expect_v that_o pleasant_a sensation_n may_v cause_v quite_o contrary_a effect_n to_o that_o of_o grievous_a sensation_n viz._n relaxation_n and_o all_o its_o effect_n
benefit_n as_o in_o many_o of_o the_o former_a to_o be_v short_a it_o be_v good_a and_o useful_a in_o all_o pain_n and_o grievous_a sensation_n 1._o eecept_n all_o such_o as_o tend_v to_o the_o speedy_a and_o timely_a benefit_n of_o person_n as_o those_o in_a woman_n labour_n grievance_n at_o stomach_n that_o cause_n vomit_v upon_o over-repletion_n or_o by_o reason_n of_o somewhat_o that_o grieve_v and_o be_v not_o convenient_a to_o stay_v at_o stomach_n or_o irritation_n to_o expectorate_v when_o much_o want_v as_o happen_v sometime_o in_o vomicas_fw-la pleurisy_n peripneumonias_n etc._n etc._n or_o such_o as_o irritate_fw-la and_o solicit_v to_o make_v water_n go_v to_o stool_n etc._n etc._n when_o evacuation_n of_o urine_n ordure_n ill_a humour_n etc._n etc._n be_v requisite_a 2._o except_o when_o grievous_a sensation_n be_v necessary_a call_n or_o intimation_n for_o supply_v refreshment_n etc._n etc._n as_o hunger_n thirst_v etc._n etc._n which_o shall_v be_v take_v off_o only_o by_o the_o pleasure_n of_o good_a meat_n and_o drink_v lest_o nature_n be_v defraud_v where_o you_o may_v observe_v a_o inconvenience_n that_o may_v happen_v by_o the_o frequent_a use_n of_o opium_n take_v away_o appetite_n without_o nutriment_n though_o this_o be_v much_o compensated_a by_o the_o relaxation_n and_o recruit_v that_o opiate_n give_v and_o their_o moderate_v the_o expense_n of_o spirit_n by_o take_v of_o contraction_n and_o may_v more_o if_o not_o whole_o by_o a_o regular_a and_o constant_a way_n of_o eat_v and_o drink_v temperate_o at_o usual_a time_n though_o the_o hunger_n may_v not_o by_o reason_n of_o the_o opiate_n be_v so_o great_a as_o at_o other_o time_n i._o the_o form_n be_v indifferent_a and_o to_o be_v order_v only_o according_a to_o the_o general_a rule_n remember_v that_o the_o liquid_a be_v best_a for_o speed_n ii_o the_o dose_n must_v be_v proportion_v to_o the_o pain_n or_o grievous_a sensation_n and_o always_o rather_o more_o than_o when_o there_o be_v no_o pain_n because_o its_o contraction_n oppose_v the_o relaxation_n to_o be_v induce_v by_o the_o opiate_n observe_v this_o method_n first_o give_v a_o good_a do_v then_o stay_v about_o 2_o or_o 3_o hour_n and_o if_o the_o pain_n be_v not_o at_o all_o lessen_v you_o may_v safe_o then_o give_v half_a the_o quantity_n again_o and_o afterward_o about_o a_o three_o part_n of_o the_o do_v every_o 2_o or_o 3_o hour_n till_o it_o begin_v to_o abate_v but_o upon_o the_o least_o sensible_a abatement_n you_o must_v forbear_v to_o give_v any_o more_o because_o that_o which_o do_v in_o some_o measure_n abate_v the_o pain_n do_v in_o the_o same_o proportion_n abate_v the_o contraction_n and_o consequent_o it_o have_v less_o to_o contest_v with_o therefore_o will_v be_v sure_a to_o conquer_v it_o for_o the_o same_o power_n that_o can_v subdue_v ten_o in_o some_o measure_n will_v subdue_v nine_o in_o a_o great_a measure_n and_o eight_o more_o easy_o than_o nine_o etc._n etc._n till_o the_o pain_n quite_o cease_v whereas_o if_o you_o add_v more_o power_n to_o the_o opiate_n it_o may_v be_v too_o much_o especial_o when_o the_o pain_n be_v thereby_o conquer_v and_o that_o it_o have_v no_o contraction_n to_o contest_v with_o for_o than_o it_o will_v be_v as_o if_o a_o great_a do_v be_v give_v to_o one_o that_o have_v no_o pain_n but_o if_o the_o pain_n increase_v again_o you_o may_v safe_o repeat_v the_o half_n do_v etc._n etc._n every_o 2_o or_o 3_o hour_n till_o it_o again_o begin_v to_o abate_v and_o no_o long_o which_o you_o have_v better_o observe_v to_o do_v as_o soon_o as_o ever_o the_o pain_n begin_v to_o return_v because_o it_o take_v some_o time_n to_o operate_v it_o sollow_v then_o that_o the_o liquid_a form_n be_v most_o convenient_a in_o this_o case_n for_o expedition_n my_o particular_a and_o effectual_a manner_n of_o use_v it_o in_o the_o gout_n will_v be_v somewhat_o too_o redious_a to_o be_v set_v down_o therefore_o since_o it_o may_v be_v obvious_a enough_o to_o the_o sagacious_a that_o consider_v what_o have_v be_v say_v and_o the_o nature_n of_o the_o distemper_n i_o will_v pass_v that_o by_o at_o this_o time_n iii_o the_o vehicle_n in_o cold_a stomach_n and_o constitution_n may_v be_v a_o glass_n of_o wine_n or_o some_o temperate_a cordial_n but_o in_o hot_a case_n or_o where_o a_o fever_n be_v fear_v emulsion_n milk_n and_o water_n or_o water_n alone_o or_o other_o acceptable_a cool_a thing_n or_o such_o as_o be_v direct_v in_o the_o case_n of_o procure_v relaxation_n in_o the_o last_o chapter_n because_o it_o be_v relaxation_n that_o take_v away_o pain_n as_o have_v be_v mechanical_o demonstrate_v but_o heâ—e_v there_o be_v no_o need_n of_o be_v scrupulous_a as_o to_o the_o vehicle_n unless_o it_o be_v in_o respect_n of_o heat_n and_o cold_a as_o the_o case_n happen_v iv_o the_o time_n may_v be_v any_o hour_n as_o the_o case_n require_v only_o remember_v that_o sleep_n conduce_v much_o to_o relaxation_n and_o therefore_o to_o the_o take_v away_o of_o pain_n v._o the_o regimen_n to_o be_v use_v in_o the_o case_n of_o relax_v in_o the_o last_o chapter_n will_v suffice_v but_o it_o be_v convenient_a as_o be_v say_v to_o regard_v the_o stomach_n and_o hot_a and_o cold_a constitution_n especial_o where_o there_o be_v any_o fear_n of_o fever_n by_o give_v cool_a liquid_n as_o emulsion_n etc._n etc._n and_o avoid_v hot_a or_o solid_a thing_n especial_o such_o as_o be_v hard_a of_o digestion_n as_o flâ—sh_v fish_n egg_n etc._n etc._n 1._o note_v that_o it_o be_v very_o advisable_v not_o to_o defer_v the_o use_n of_o opiate_n too_o long_o till_o people_n be_v very_o weak_a though_o it_o may_v seem_v that_o they_o will_v hinder_v some_o due_a evacuation_n for_o i_o can_v see_v what_o harm_n a_o refreshment_n by_o they_o may_v do_v any_o more_o than_o by_o sleep_n both_o depend_v upon_o the_o same_o cause_n viz._n relaxation_n it_o be_v true_a that_o by_o reason_n of_o sleep_n or_o a_o opiate_n the_o evacuation_n may_v be_v a_o little_a defer_v what_o then_o will_v any_o man_n deny_v sleep_n for_o that_o reason_n why_o then_o shall_v a_o physician_n deny_v a_o opiate_n to_o cause_v it_o respite_n nature_n and_o enable_v it_o to_o bear_v its_o burden_n or_o engage_v with_o difficulty_n the_o better_a 2._o remember_v always_o that_o sleep_n be_v a_o great_a help_n to_o take_v away_o pain_n and_o so_o be_v all_o thing_n that_o conduce_v to_o relaxation_n or_o pleasant_a diversion_n 3._o use_v means_n in_o pain_n of_o the_o hemorrhoid_v furdament_n or_o intestinum_fw-la rectum_fw-la and_o indeed_o in_o any_o pain_n within_o the_o gut_n unless_o it_o proceed_v from_o a_o looseness_n that_o opiate_n may_v not_o bind_v man_n too_o much_o as_o leâ—itives_n internal_o or_o emollient_a 〈◊〉_d or_o which_o of_o they_o may_v be_v most_o easy_o and_o convenient_o do_v and_o most_o to_o the_o purpose_n chap._n xxxv_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o cause_n sleep_n it_o primary_o cause_n sleep_v by_o relax_v and_o compose_v quiet_v soothe_v please_a and_o lull_v the_o sensitive_a soul_n and_o spirit_n it_o always_o relax_n but_o do_v not_o always_o sufficient_o compose_v or_o quiet_v the_o spirit_n to_o cause_n sleep_n to_o which_o both_o be_v requisite_a secundary_o by_o take_v away_o grievous_a passion_n or_o sensation_n when_o they_o happen_v to_o hinder_v it_o 1._o as_o soporiserous_a it_o be_v of_o incomparable_a use_n in_o all_o troublesome_a watch_n whether_o they_o be_v from_o grievous_a passion_n or_o sensation_n or_o irrequiete_a motion_n of_o the_o spirit_n though_o not_o so_o certain_a in_o this_o last_o case_n as_o in_o the_o former_a and_o therefore_o prove_v sometime_o unsuccessful_a in_o some_o person_n and_o in_o some_o sort_n of_o madness_n as_o the_o merry_a or_o furicus_n though_o it_o be_v effectual_a in_o melancholy_n and_o slow_a manias_fw-la as_o have_v be_v intimate_v for_o bare_a relaxation_n suffice_v in_o the_o two_o first_o case_n where_o sleep_n be_v hinder_v by_o contraction_n which_o it_o never_o fail_v to_o take_v off_o if_o give_v in_o a_o due_a quantity_n as_o have_v be_v direct_v 2._o to_o recruit_v the_o spirit_n as_o when_o people_n be_v tire_v with_o labour_n journey_n disease_n conflict_n of_o nature_n as_o by_o convulsion_n vomit_n purge_n hysteric_a fit_n and_o the_o like_a 3._o to_o relax_v compose_v take_v away_o pain_n moderate_a flux_n that_o depend_v upon_o grievous_a sensation_n or_o irritation_n and_o its_o consequent_a contraction_n or_o from_o motion_n or_o segregation_n of_o humour_n 4._o to_o promote_v flux_n that_o depend_v upon_o relaxation_n as_o perspiration_n sweat_v as_o also_o the_o menses_fw-la and_o lochia_n in_o some_o case_n of_o all_o which_o you_o have_v particular_a chapter_n which_o see_v i._o the_o form_n may_v be_v indifferent_o either_o solid_a or_o liquid_a as_o
of_o wine-drinker_n you_o may_v easy_o perceive_v by_o what_o have_v be_v say_v why_o our_o opium_n have_v so_o much_o filth_n in_o it_o why_o it_o taste_v sometime_o of_o a_o empyreum_fw-la or_o burn_v in_o not_o stir_v it_o well_o while_o it_o be_v boil_v into_o a_o consistence_n and_o not_o give_v it_o only_o a_o gentle_a heat_n when_o it_o begin_v to_o thicken_v gradual_o lessen_v the_o fire_n or_o let_v it_o convenient_o decay_n and_o go_v out_o of_o itself_o which_o be_v a_o very_a good_a way_n for_o such_o as_o have_v not_o other_o convenience_n for_o as_o the_o matter_n thicken_v the_o heat_n decline_v and_o so_o become_v safe_a from_o a_o taste_n of_o burn_v if_o the_o fire_n be_v due_o proportion_v but_o all_o this_o trouble_n be_v avoid_v by_o inspissate_v by_o the_o heat_n of_o the_o sun_n which_o be_v use_v in_o some_o country_n note_v that_o the_o poppy_n of_o which_o opium_n be_v make_v in_o all_o turkey_n egypt_n thebes_n etc._n etc._n be_v the_o great_a white_a poppy_n which_o grow_v very_o free_o in_o those_o part_n and_o as_o i_o be_o inform_v without_o any_o manure_n of_o the_o ground_n in_o some_o place_n certain_a it_o be_v that_o they_o now_o have_v whole_a field_n of_o that_o white_a poppy_n out_o of_o which_o they_o make_v the_o opium_n as_o be_v aforesaid_a by_o pound_v press_v boil_a etc._n etc._n chap._n ii_o of_o the_o election_n or_o choice_n of_o opium_n all_o opium_n be_v make_v in_o ancient_a time_n by_o the_o milky_a drop_n that_o fall_v out_o of_o the_o incision_n mention_v in_o the_o last_o chapter_n which_o be_v a_o natural_a and_o simple_a way_n make_v no_o difference_n in_o the_o opium_n but_o what_o nature_n itself_o do_v all_o their_o knowledge_n of_o the_o best_a opium_n consist_v in_o distinguish_v the_o theban_a from_o other_o opium_n which_o be_v not_o natural_o so_o good_a 1._o theban_a opium_n be_v of_o a_o light_a reddish_n yellow_a than_o other_o sort_n therefore_o some_o call_v it_o white_a opium_n not_o that_o it_o be_v abjolute_o white_a but_o only_o relative_o such_o in_o comparison_n with_o other_o kind_n of_o opium_n as_o we_o say_v white_a rosin_n in_o respect_n of_o other_o rosin_n tho'_o it_o be_v not_o white_a but_o only_o light_a colour_v than_o other_o rosin_n 2._o theban_a opium_n be_v most_o hot_a bitter_a and_o bite_v in_o taste_n from_o whence_o you_o may_v infer_v that_o the_o opium_n which_o have_v those_o quality_n in_o the_o high_a degree_n be_v the_o best_a 3._o it_o smell_v rank_o and_o vehement_o of_o the_o poppy_n which_o give_v you_o another_o good_a sign_n to_o judge_v of_o opium_n 4._o it_o burn_v with_o a_o clear_a flame_n than_o any_o other_o 5._o some_o say_v that_o it_o be_v weighty_a than_o other_o sort_n notwithstanding_o all_o which_o difference_n they_o do_v in_o time_n find_v way_n to_o adulterate_v it_o which_o be_v these_o 1._o they_o adulterate_v it_o with_o juice_n of_o glauciam_fw-la or_o apple_n of_o love_n this_o be_v discernible_a by_o the_o yellow_a tincture_n that_o it_o give_v to_o water_n and_o other_o menstruum_n whereas_o the_o theban_a and_o all_o true_a opium_n give_v a_o red_a tincture_n 2._o it_o be_v counterfeit_v with_o resinous_a thing_n this_o cheat_n be_v discoverable_a by_o its_o not_o be_v uniform_a nor_o so_o dissolvable_a in_o water_n as_o good_a opium_n 3._o it_o be_v mix_v with_o juice_n of_o lactuca_n sylvestris_n or_o wild_a endive_n leave_a lettuce_n this_o make_v it_o of_o a_o dull_a colour_n and_o not_o to_o smell_v so_o perfect_o and_o rank_o of_o the_o poppy_n 4._o it_o be_v sometime_o mix_v with_o the_o milky_a juice_n of_o spurge_n which_o be_v hot_a bitter_a and_o bite_a be_v hardly_o discernible_a but_o by_o its_o purge_n and_o disturb_v quality_n and_o somewhat_o less_o and_o different_a you_o may_v be_v sure_a that_o this_o and_o all_o the_o other_o mixture_n lessen_v its_o virtue_n as_o a_o opiate_n if_o consider_v in_o the_o same_o quantity_n because_o they_o must_v take_v up_o room_n in_o the_o mass_n but_o lactuca_n sylvestris_n be_v of_o the_o nature_n of_o opium_n make_v the_o loss_n of_o its_o virtue_n less_o discernible_a it_o be_v true_a that_o we_o have_v none_o of_o the_o opium_n that_o be_v gather_v by_o the_o milky_a drop_n out_o of_o the_o incision_n and_o therefore_o what_o be_v say_v do_v not_o much_o concern_v we_o as_o to_o that_o sort_n however_o these_o observation_n will_v enlighten_v we_o as_o to_o the_o opium_n that_o we_o now_o have_v of_o which_o i_o can_v find_v that_o there_o be_v much_o adulteration_n use_v because_o i_o suppose_v that_o it_o be_v now_o grow_v considerable_o cheap_a by_o reason_n of_o the_o vast_a quantity_n that_o be_v make_v with_o so_o much_o ease_n that_o it_o be_v not_o worth_a while_n to_o counterfeit_v it_o there_o be_v now_o great_a field_n of_o poppy_n in_o turkey_n so_o that_o our_o business_n will_v be_v rather_o to_o distinguish_v the_o sort_n than_o the_o adulteration_n tho'_o this_o shall_v not_o pass_v unregarded_a as_o far_o as_o it_o may_v concern_v we_o there_o be_v two_o sort_n bring_v over_o to_o we_o one_o from_o persia_n and_o the_o east-indies_n the_o other_o from_o turkey_n as_o from_o lesser_n asia_n or_o anatolia_n smyrna_n aleppo_n etc._n etc._n i._o that_o which_o be_v bring_v from_o east-india_n persia_n surat_n etc._n etc._n be_v as_o i_o be_o inform_v make_v of_o the_o leave_n and_o stem_n of_o the_o poppy_n and_o be_v 1._o more_o full_a of_o filth_n within_o it_o for_o the_o outside_n be_v not_o so_o much_o to_o be_v regard_v because_o of_o accident_n 2._o it_o be_v not_o so_o uniform_a smooth_a and_o supple_a but_o harsh_a and_o rugged_a 3._o it_o be_v not_o so_o ready_o dissolvable_a in_o water_n 4._o the_o indian_a be_v bring_v over_o in_o large_a piece_n 5._o it_o be_v not_o bring_v so_o wrap_v in_o leave_n as_o the_o turkey_n opium_n be_v bontius_n say_v that_o they_o make_v it_o of_o the_o stem_n and_o leave_n if_o so_o it_o must_v be_v much_o worse_a than_o the_o turkey_n opium_n that_o be_v make_v of_o the_o head_n and_o leave_n ii_o among_o those_o sort_n that_o be_v bring_v out_o of_o turkey_n and_o indeed_o any_o sort_n of_o opium_n 1._o that_o be_v best_a that_o be_v most_o bitter_a hot_a and_o bite_v 2._o the_o light_a white_a and_o clear_a its_o flame_n be_v when_o it_o burn_v the_o better_a it_o be_v 3._o the_o more_o uniform_a even_o smooth_a tough_a yield_a and_o comply_v it_o be_v to_o be_v wrought_v or_o bring_v to_o any_o form_n the_o better_a it_o be_v 4._o the_o more_o it_o give_v upon_z or_o against_o moist_a wether_n or_o in_o a_o moist_a air_n of_o any_o kind_n and_o the_o better_a speedy_a free_a and_o more_o perfect_o it_o dissolve_v in_o water_n the_o better_a it_o be_v 5._o the_o red_a the_o tincture_n be_v that_o it_o give_v in_o water_n spirit_n of_o wine_n or_o any_o menstruum_fw-la the_o better_a it_o be_v and_o it_o be_v never_o good_a if_o it_o give_v only_o a_o yellow_a tincture_n but_o note_v that_o even_o the_o best_a opium_n if_o you_o take_v but_o a_o very_a slight_a tincture_n thereof_o will_v appear_v yellowish_a especial_o in_o a_o white_a vessel_n therefore_o my_o meaning_n be_v that_o the_o red_a tincture_n opium_n cause_v in_o water_n quantity_n for_o quantity_n the_o better_a it_o be_v 6._o it_o shall_v have_v no_o taste_n or_o smell_v of_o a_o empyreum_fw-la or_o burn_v for_o that_o give_v it_o a_o nauseous_a taste_n and_o in_o some_o measure_n signify_v a_o loss_n of_o its_o virtue_n by_o burn_v tho'_o this_o may_v be_v inconsiderable_a 7._o the_o less_o filth_n it_o have_v on_o the_o inside_n the_o better_a it_o be_v 8._o the_o more_o it_o sparkle_v when_o cut_v and_o afterward_o breathe_v upon_o three_o or_o four_o time_n the_o true_a be_v the_o opium_n for_o those_o sparkle_a particle_n be_v its_o noble_a volatile_a salt_n or_o sal._n volatile-oleosum_a and_o not_o its_o resinous_a part_n as_o wedelcus_fw-la and_o other_o affirm_v 1._o because_o when_o the_o rosin_n and_o volatile_a salt_n be_v separate_v that_o sparkle_a follow_v the_o volatile_a part_n and_o not_o the_o rosin_n wherein_o they_o do_v not_o appear_v in_o the_o least_o 2._o because_o i_o find_v that_o they_o be_v the_o part_n that_o be_v most_o apt_a to_o dissolve_v in_o water_n which_o the_o rosin_n be_v not_o 3._o because_o they_o be_v much_o alter_v by_o a_o warm_a and_o moist_a breath_n which_o the_o resinous_a part_n be_v not_o 4._o how_o can_v that_o opium_n be_v the_o best_a as_o it_o be_v find_v to_o be_v that_o have_v most_o of_o they_o if_o it_o be_v the_o rosin_n which_o be_v the_o worst_a part_n of_o opium_n but_o it_o be_v high_o consonant_a to_o experience_n that_o they_o shall_v be_v the_o volatile_a or_o
good_a humour_a of_o which_o he_o be_v seldom_o capable_a and_o utter_o incapable_a of_o all_o or_o most_o of_o the_o other_o brisk_a effect_n as_o euphory_n promptitude_n to_o venus_n exertion_n of_o courage_n etc._n etc._n it_o be_v either_o pass_v by_o as_o a_o ordinary_a thing_n of_o course_n and_o so_o not_o heed_v or_o else_o impute_v to_o refreshment_n by_o sleep_n ease_n from_o pain_n or_o some_o amendment_n as_o to_o the_o disease_n or_o indeed_o to_o any_o thing_n rather_o than_o dispiriting_n and_o stupify_a opium_n that_o be_v so_o far_o in_o all_o opinion_n from_o exciting_a the_o spirit_n that_o all_o affirm_v conclude_v and_o agree_v that_o it_o diminish_v or_o disable_v they_o the_o like_a be_v to_o be_v say_v of_o any_o of_o the_o lively_a effect_n in_o case_n they_o happen_v and_o be_v observe_v though_o i_o do_v not_o see_v how_o they_o can_v so_o at_o least_o as_o any_o slander_n by_o will_v refer_v it_o to_o opium_n beside_o that_o as_o to_o some_o of_o the_o brisk_a effect_n especial_o that_o of_o venery_n great_a dose_n be_v requisite_a to_o render_v it_o any_o thing_n remarkable_a than_o be_v use_v in_o these_o western_a part_n and_o that_o modesty_n will_v much_o hinder_v the_o discovery_n of_o this_o effect_n be_v it_o not_o therefore_o very_o manifest_a that_o i_o have_v great_a cause_n to_o suspect_v that_o both_o ancient_n and_o modern_a physician_n consider_v thing_n by_o half_n since_o they_o do_v not_o take_v the_o most_o genuine_a property_n into_o their_o consideration_n and_o that_o they_o lay_v their_o foundation_n upon_o the_o most_o contrary_a effect_n to_o they_o it_o follow_v then_o that_o the_o general_a supposition_n of_o all_o the_o learned_a can_v no_o more_o solve_v the_o true_a property_n of_o opium_n in_o any_o probability_n than_o give_v the_o reason_n why_o fire_n harden_v clay_n can_v explain_v why_o it_o soften_v wax_n the_o reason_n do_v i_o say_v i_o shall_v have_v say_v than_o give_v the_o wrong_a reason_n why_o it_o harden_v clay_n show_v how_o it_o soften_v wax_n for_o it_o will_v appear_v in_o the_o follow_a chapter_n that_o they_o give_v no_o right_a reason_n for_o any_o effect_n of_o opium_n even_o those_o they_o ever_o allow_v to_o be_v its_o effect_n nor_o lay_v any_o true_a foundation_n to_o explain_v the_o least_o mean_a and_o plain_a effect_n thereof_o forasmuch_o as_o all_o their_o supposition_n be_v so_o false_a that_o there_o never_o be_v any_o such_o thing_n as_o they_o lie_v down_o to_o explain_v the_o effect_n of_o opium_n viz._n 1._o no_o such_o thing_n as_o a_o cold_a quality_n in_o opium_n 2._o no_o such_o thing_n as_o fume_n etc._n etc._n fly_v from_o opium_n to_o the_o brain_n while_o it_o be_v at_o stomach_n 3._o no_o such_o thing_n as_o diminish_v or_o disable_n the_o animal_n spirit_n by_o opium_n any_o way_n whatsoever_o of_o which_o in_o their_o order_n in_o the_o follow_a chapter_n chap._n ix_o it_o be_v prove_v that_o opium_n have_v no_o cold_a quality_n to_o diminish_v or_o disable_v the_o spirit_n thereby_o have_v show_v just_a cause_n of_o my_o suspicion_n of_o that_o universal_a foundation_n of_o opium_n diminish_v or_o disable_n the_o spirit_n i_o will_v now_o proceed_v to_o a_o more_o strict_a examination_n thereof_o beginning_n with_o the_o opinion_n of_o the_o ancient_n who_o affirm_v that_o opium_n diminish_v or_o disable_v the_o spirit_n by_o a_o extreme_a cold_a quality_n i_o confess_v that_o much_o may_v be_v do_v towards_o the_o diminish_n or_o disable_n the_o spirit_n by_o opium_n if_o it_o have_v such_o a_o cold_a quality_n as_o the_o ancient_n attribute_v to_o it_o for_o than_o it_o must_v be_v such_o a_o coldness_n as_o the_o cold_a thing_n either_o actual_a or_o potential_a bear_v no_o proportion_n to_o for_o ice_n snow_n etc._n etc._n bear_v no_o proportion_n to_o it_o in_o cause_v the_o same_o effect_n by_o a_o cold_a quality_n it_o be_v the_o manner_n of_o the_o ancient_n implicit_o to_o believe_v and_o subscribe_v to_o what_o their_o great_a author_n and_o master_n in_o physic_n or_o philosophy_n teach_v they_o who_o they_o adore_v as_o infallible_a god_n as_o soon_o as_o their_o mortality_n prove_v the_o contrary_a which_o be_v as_o absurd_a as_o assert_v tha_z opium_n which_o be_v one_o of_o the_o hot_a thing_n that_o vegetable_n afford_v be_v extreme_a cold_a bless_a be_v god_n for_o our_o light_n in_o religion_n and_o liberty_n in_o philosophy_n therefore_o some_o such_o admire_a author_n or_o great_a master_n in_o physic_n have_v assert_v that_o opium_n act_v by_o a_o extreme_a cold_a quality_n all_o do_v implicit_o subscribe_v to_o it_o the_o devil_n who_o they_o worship_v can_v not_o though_o a_o deceiver_n from_o the_o beginning_n impose_v more_o upon_o their_o faith_n than_o in_o cause_v they_o for_o i_o can_v think_v but_o it_o be_v some_o such_o evil_a power_n to_o believe_v that_o opium_n be_v cold_a against_o all_o the_o evidence_n of_o sense_n and_o experience_n he_o may_v have_v as_o well_o tell_v they_o that_o hell_n fire_n have_v all_o the_o property_n of_o common_a culinary_a fire_n and_o yet_o nothing_o more_o refresh_v by_o its_o cold_a quality_n for_o as_o many_o of_o our_o sense_n as_o can_v take_v notice_n of_o heat_n and_o cold_a do_v plain_o inform_v we_o that_o it_o be_v very_o hot_a in_o itself_o and_o effect_n for_o 1._o it_o be_v taste_n be_v very_o bitter_a rank_a vehement_o hot_a burn_a and_o bite_v all_o which_o quality_n be_v infallible_a sign_n of_o great_a heat_n and_o the_o better_a the_o opium_n be_v the_o more_o intense_a be_v those_o quality_n nay_o it_o be_v observe_v that_o its_o very_a virtue_n be_v strict_o combine_v to_o or_o consist_v in_o those_o quality_n especial_o bitterness_n which_o if_o lose_v the_o virtue_n be_v go_v as_o be_v common_o observe_v and_o easy_o observable_a it_o be_v a_o wise_a fetch_v of_o amatus_fw-la lusitanus_n in_o defence_n of_o its_o cold_a quality_n to_o attribute_v all_o its_o bitterness_n to_o glaucium_fw-la that_o be_v mix_v therewith_o whereas_o glaucium_fw-la always_o give_v a_o yellow_a tincture_n to_o water_n and_o opium_n a_o red_a but_o the_o opium_n that_o give_v no_o yellow_a tincture_n be_v bitter_a also_o yea_o that_o be_v most_o bitter_a that_o give_v the_o red_a tincture_n how_o come_v theban_a opium_n and_o indeed_o all_o other_o opium_n to_o be_v bitter_a before_o any_o thing_n be_v mix_v with_o it_o how_o inadvertent_o absurd_a people_n will_v be_v to_o defend_v absurdity_n it_o be_v pretty_a to_o see_v how_o they_o will_v expose_v themselves_o to_o defend_v a_o false_a opinion_n 2._o it_o be_v smell_n which_o be_v very_a rank_n strong_a hot_a and_o such_o as_o thing_n high_o impregnate_v with_o volatile_a salt_n and_o sulphur_n the_o two_o hot_a principle_n in_o nature_n do_v afford_v it_o be_v from_o volatile_a salt_n that_o cantharides_n pismire_n spear-wort_n crowsfoot_n etc._n etc._n be_v so_o very_o hot_a as_o to_o blister_v or_o exulcerate_v and_o be_v not_o all_o hot_a spirit_n such_o upon_o the_o account_n of_o their_o sulphur_n as_o spirit_n of_o wine_n brandy_n etc._n etc._n 3._o the_o best_a and_o strong_a opium_n will_v also_o exulcerate_v as_o all_o author_n agree_v which_o only_a fire_n or_o such_o thing_n as_o have_v the_o particle_n of_o fire_n lodge_v in_o they_o as_o lixiviate_n etc._n etc._n or_o the_o hot_a thing_n in_o nature_n will_v do_v as_o cantharides_n spear-wort_n etc._n etc._n it_o be_v 4._o for_o the_o like_a reason_n a_o psilothrick_n or_o causer_n of_o hair_n to_o fall_v which_o only_a lime_n orpâ—ment_n and_o the_o hot_a thing_n do_v cause_n 5._o it_o be_v inflammable_a which_o only_o sulphurecus_fw-la thing_n be_v 6._o it_o cause_v a_o sense_n of_o a_o vehement_a heat_n at_o stomach_n though_o take_v but_o in_o the_o quantity_n of_o a_o drachm_n 7._o it_o cause_v dryness_n of_o the_o mouth_n and_o thirst_v though_o take_v but_o in_o the_o quantity_n of_o 3_o grain_n which_o nothing_o do_v but_o hot_a thing_n 8._o it_o discuss_n and_o all_o discusser_n be_v hot_a for_o it_o be_v by_o heat_n that_o they_o do_v discuss_v as_o spirit_n of_o wine_n cummin-seed_n volatile_a salt_n and_o all_o hot_a spirit_n 9_o it_o soon_o operate_v and_o in_o a_o small_a quantity_n which_o be_v a_o infallible_a proof_n of_o the_o activity_n of_o its_o part_n which_o argue_v heat_n not_o cold._a 10._o it_o cause_v a_o gay_a pleasant_a and_o merry_a humour_n which_o only_a wine_n and_o hot_a liquor_n etc._n etc._n do_v and_o one_o grain_n of_o opium_n will_v cause_v they_o as_o much_o as_o several_a glass_n of_o wine_n which_o argue_v that_o its_o heat_n be_v much_o great_a 11._o i_o will_v fain_o know_v how_o or_o see_v any_o instance_n of_o any_o cold_a thing_n raise_v the_o spirit_n cause_v courage_n magnanimity_n enable_v people_n to_o labour_n journey_n etc._n
we_o need_v not_o be_v solicitous_a only_o tell_v you_o that_o it_o have_v much_o of_o earth_n and_o water_n in_o it_o and_o more_o or_o less_o of_o that_o according_a to_o its_o foulness_n and_o of_o this_o according_a to_o its_o moistness_n or_o dryness_n and_o that_o it_o always_o have_v more_o water_n in_o it_o in_o moist_a wether_n for_o i_o never_o know_v any_o thing_n so_o apt_a to_o take_v in_o moisture_n and_o to_o alter_v according_o in_o its_o substance_n though_o not_o in_o virtue_n insomuch_o that_o i_o have_v use_v it_o as_o a_o indicator_n of_o the_o wether_n and_o it_o never_o sail_v to_o show_v the_o degree_n of_o moisture_n in_o the_o air_n if_o it_o be_v keep_v in_o a_o convenient_a place_n where_o accident_n as_o the_o sun_n fire_n etc._n etc._n may_v not_o alter_v the_o case_n and_o always_o in_o the_o same_o place_n our_o business_n therefore_o be_v to_o inquire_v after_o the_o active_a principle_n of_o opium_n i_o shall_v proceed_v in_o this_o plain_a and_o natural_a method_n v._o z._n i_o shall_v inquire_v 1._o which_o be_v the_o predominant_a active_a principle_n of_o opium_n and_o how_o combine_v etc._n etc._n 2._o which_o of_o they_o produce_v the_o good_a and_o laudable_a effect_n of_o opium_n and_o why_o 3._o which_o of_o they_o produce_v its_o ill_a effect_n and_o why_o 1._o as_o to_o its_o active_a principle_n which_o be_v predominant_a first_o it_o manifest_o appear_v that_o opium_n be_v high_o impregnate_v with_o volatile_a salt_n 1._o by_o its_o bite_n and_o pungent_a taste_n which_o be_v the_o certain_a effect_n of_o volatile_a salt_n as_o in_o mustard_n horseradish_n cress_n arum_fw-la or_o wake_v robin_n scurvigrass_n rochet_n spearwort_n crowsfoot_o squill_n radish_n arsmart_n onion_n garlic_n and_o very_o many_o plant_n of_o the_o same_o kind_a which_o have_v their_o bite_n and_o pungent_a taste_n as_o all_o know_v and_o allow_v from_o their_o volatile_a salt_n and_o so_o have_v all_o plant_n of_o the_o like_a taste_n which_o be_v therefore_o common_o esteem_v to_o be_v antiscorbutic_n 2._o by_o its_o rank_n and_o vehement_a smell_n be_v such_o as_o be_v by_o the_o common_a consent_n of_o the_o learned_a always_o attribute_v to_o volatile_a salt_n alone_o or_o join_v with_o some_o oily_a part_n as_o the_o smell_n of_o semen_n virile_a to_o which_o i_o take_v that_o of_o opium_n to_o be_v most_o like_a of_o burn_a hoof_n horn_n skin_n membrane_n etc._n etc._n garlick_n onion_n rocket_n pismire_n soot_n etc._n etc._n 3._o by_o its_o ready_a dissolution_n in_o water_n moist_a air_n etc._n etc._n which_o must_v be_v from_o its_o volatile_a salt_n because_o it_o have_v very_o little_o fix_v salt_n and_o because_o volatile_a salt_n be_v the_o most_o dissolvable_a salt_n that_o be_v in_o vegetable_n before_o they_o have_v pass_v the_o fire_n 4._o by_o its_o dissolution_n in_o spirit_n of_o wine_n which_o volatile_a salt_n be_v more_o apt_a to_o do_v than_o fix_a salt_n and_o this_o be_v one_o reason_n why_o it_o be_v so_o apt_a to_o dissolve_v in_o all_o menstruum_n especial_o the_o three_o main_a one_o viz._n the_o wâ—ry_n the_o salino-volatile_a as_o spirit_n of_o salt_n ammoniac_a spirit_n of_o hartshorn_n etc._n etc._n and_o the_o spirituosulphureous_a as_o spirit_n of_o wine_n brandy_n etc._n etc._n in_o which_o last_o thing_n its_o sulphur_n that_o be_v join_v with_o the_o volatile_a salt_n do_v much_o help_n it_o to_o dissolve_v 5._o by_o its_o incide_v and_o discuss_v quality_n when_o external_o apply_v which_o quality_n must_v be_v attribute_v to_o its_o volatile_a salt_n it_o have_v no_o other_o principle_n that_o can_v cause_v those_o quality_n especial_o in_o that_o eminent_a degree_n as_o opium_n have_v they_o and_o see_v it_o be_v not_o a_o thing_n that_o have_v undergo_v fermentation_n as_o vinous_a spirit_n and_o that_o it_o have_v but_o one_o in_o 32_o of_o the_o fix_a salt_n in_o its_o mass_n as_o the_o most_o excellent_a dr._n crew_n prove_v 6._o by_o its_o resolve_v quality_n be_v external_o apply_v for_o resolution_n be_v cause_v by_o such_o part_n as_o easy_o penetrate_v and_o mix_v with_o our_o skin_n flesh_n etc._n etc._n and_o such_o as_o do_v so_o must_v be_v of_o like_a active_a principle_n with_o our_o part_n for_o all_o know_v that_o easiness_n of_o mixture_n be_v by_o likeness_n of_o part_n and_o the_o active_a principle_n of_o our_o skin_n flesh_n etc._n etc._n be_v volatile_a salt_n join_v with_o some_o oily_a particle_n as_o have_v be_v say_v therefore_o opium_n must_v have_v such_o principle_n to_o be_v so_o great_a a_o resolver_n hence_o it_o be_v that_o gum_n ammoniacum_n hemlock_n and_o several_a gum_n plant_n etc._n etc._n that_o be_v saturate_v with_o volatile_a salt_n be_v such_o good_a resolver_n but_o it_o be_v worth_a a_o very_a particular_a remark_n that_o all_o narcotick_a plant_n be_v very_o eminent_a yea_o the_o very_o best_a resolver_n of_o hard_a tumour_n and_o the_o like_a as_o solanum_fw-la lethale_n or_o deadly_a nightshade_n hemlock_n henbane_n mandrake_n and_o the_o more_o narcotick_a they_o be_v the_o more_o resolve_v 7._o by_o its_o exulcerate_v or_o blister_a quality_n which_o be_v but_o a_o strong_a â—ort_n of_o resolution_n of_o part_n which_o the_o best_a and_o strong_a opium_n that_o be_v gather_v by_o drop_n out_o of_o the_o incision_n of_o the_o poppy_n head_n as_o author_n testify_v and_o the_o best_a we_o have_v as_o some_o say_v will_v do_v upon_o very_o tender_a skin_n or_o at_o least_o rubisy_n as_o mustard_n etc._n etc._n will_n which_o most_o evident_o prove_v its_o volatile_a salt_n for_o all_o blisterer_n as_o cantharides_n pismire_n crowsfoot_o spearwort_n garlick_n etc._n etc._n do_v it_o upon_o the_o account_n of_o their_o volatile_a salt_n unless_o it_o be_v lexiuâ—als_n which_o have_v pass_v the_o fire_n which_o opium_n have_v not_o 8._o it_o be_v offend_v the_o eye_n as_o onion_n mustard_n etc._n etc._n do_v when_o it_o be_v apply_v thereto_o argue_v its_o volatile_a salt_n note_v that_o the_o very_o best_a opium_n as_o the_o turk_n mastach_n etc._n etc._n do_v cause_n this_o effect_v most_o of_o all_o which_o manifest_o prove_v that_o the_o virtue_n of_o opium_n do_v main_o depend_v upon_o volatile_a salt_n which_o be_v most_o certain_o the_o cause_n of_o that_o effect_n of_o exulcerate_v or_o blister_v as_o all_o do_v allow_v in_o thing_n that_o have_v not_o pass_v the_o fire_n 9_o it_o be_v psilothrick_n quality_n prove_v the_o same_o for_o it_o cause_v the_o hair_n to_o fall_v by_o the_o same_o principle_n 10._o it_o be_v eminent_a titillation_n to_o venery_n as_o cantharides_n bee_n pismire_n sem._n virile_a garlic_n onion_n leek_n horse_n radish_n mustard_n rochet_n basil_n oyster_n bear_v garlic_n crow_n garlic_n etc._n etc._n do_v most_o infallible_o argue_v the_o abundance_n of_o its_o volatile_a salt_n by_o which_o those_o thing_n and_o all_o other_o plant_n that_o have_v much_o volatile_a salt_n excite_v to_o venery_n 11._o it_o be_v aptitude_n to_o evaporate_v and_o fly_v away_o argue_v its_o volatility_n 12._o it_o be_v cause_v a_o tickle_v and_o itch_a in_o the_o skin_n do_v most_o direct_o prove_v the_o same_o nor_o do_v any_o thing_n that_o be_v take_v inward_o cause_n it_o more_o it_o must_v have_v a_o very_a titillate_v volatile_a salt_n that_o will_v in_o so_o small_a a_o quantity_n as_o opium_n be_v usual_o take_v cause_v such_o violent_a itch_n as_o it_o do_v in_o the_o skin_n after_o it_o have_v pass_v all_o digestion_n and_o concoction_n 13._o it_o be_v bitterness_n prove_v the_o same_o for_o the_o curious_a and_o most_o perspicacious_a dr._n grew_n say_v that_o bitterness_n proceed_v from_o sulphur_n well_o impregnate_v with_o alcaline_a or_o acid_a salt_n shackle_a with_o earth_n but_o it_o be_v certain_a that_o it_o be_v not_o a_o acid_n in_o opium_n for_o the_o many_o reason_n give_v and_o to_o be_v add_v he_o also_o say_v that_o when_o sulphur_n and_o the_o alcaline_a be_v more_o equal_a they_o produce_v a_o tawny_a colour_n and_o opium_n rude_o tear_v be_v tawny_a till_o the_o air_n alter_v it_o all_o which_o silvius_n confirm_v where_o he_o say_v pran_n med._n l._n ii_o cap._n xxvi_o 80._o omnia_fw-la amara_fw-la volatili_fw-la sale_n abundant_a ad_fw-la quod_fw-la constituendum_fw-la oleum_fw-la quoque_fw-la concurrit_fw-la sive_fw-la sulphur_n that_o be_v all_o bitter_a thing_n abound_v with_o volatile_a salt_n to_o constitute_v which_o oil_n or_o sulphur_n concur_v i_o can_v choose_v though_o i_o do_v not_o much_o depend_v upon_o authority_n in_o the_o general_a but_o value_v the_o assertion_n of_o such_o man_n by_o way_n of_o concurrence_n at_o least_o 14._o the_o acrimonious_a sweat_v that_o it_o cause_n prove_v the_o same_o 15._o it_o be_v also_o diuretic_n as_o and_o after_o the_o same_o manner_n with_o cantharides_n bee_n pismire_n millepedes_n scurvygrass_n horse_n radish_n etc._n etc._n that_o be_v
and_o motion_n fail_v together_o of_o the_o great_a perspiration_n and_o all_o other_o effect_n of_o relaxation_n in_o such_o syncopes_fw-la or_o leipothymy_n in_o a_o yet_o high_o degree_n than_o in_o sleep_n wherein_o the_o sensitive_a soul_n do_v not_o quite_o let_v go_v the_o reign_v of_o contraction_n as_o appear_v by_o the_o motion_n that_o remain_v as_o of_o the_o heart_n intestine_n etc._n etc._n though_o far_o more_o remiss_a in_o sleep_n than_o in_o a_o wake_v state_n note_v that_o such_o leipothymy_n be_v as_o be_v hint_v of_o the_o same_o nature_n as_o sleep_n be_v but_o that_o they_o be_v sudden_a more_o profound_a and_o not_o so_o usual_a natural_a and_o of_o course_n as_o sleep_n be_v which_o make_v they_o more_o amaze_a and_o surprise_v therefore_o it_o follow_v that_o they_o be_v as_o sleep_n be_v a_o mean_n of_o recruit_v when_o all_o work_n and_o tug_v by_o defensive_a contraction_n fail_v and_o so_o the_o last_o refuge_n of_o the_o sensitive_a soul_n when_o overtired_n in_o order_n to_o recover_v strength_n for_o a_o fresh_a engagement_n with_o the_o enemy_n as_o be_v tire_v at_o night_n the_o sensitive_a soul_n loosen_v the_o rign_n of_o contraction_n to_o enable_v he_o the_o better_a to_o fall_v to_o his_o work_n the_o next_o day_n this_o you_o will_v find_v by_o all_o reason_n and_o experience_n to_o be_v the_o true_a state_n of_o leipothymy_n upon_o grievance_n and_o fatigue_n though_o not_o hitherto_o mind_v that_o i_o know_v of_o many_o true_a and_o useful_a consequence_n do_v hence_o follow_v as_o that_o we_o be_v not_o always_o to_o disturb_v they_o or_o put_v they_o out_o of_o these_o recruit_v leipothymy_n by_o grievous_a mean_n as_o pricking_n pinch_n etc._n etc._n but_o only_o by_o cordial_n and_o refresh_a thing_n as_o you_o will_v treat_v a_o person_n much_o tire_v or_o by_o let_v they_o take_v their_o nap_n if_o i_o may_v so_o call_v it_o if_o there_o be_v not_o very_o eminent_a danger_n but_o it_o be_v endless_a and_o beside_o my_o purpose_n to_o make_v a_o particular_a discourse_n of_o this_o matter_n which_o will_v belong_v more_o proper_o to_o my_o tract_n of_o animal_n mechanism_n 14._o death_n happen_v sometime_o though_o very_o rare_o and_o that_o in_o very_o weak_a people_n that_o take_v little_a or_o no_o sustenance_n because_o either_o when_o fall_v into_o such_o syncopes_fw-la they_o never_o come_v out_o of_o they_o by_o reason_n that_o they_o have_v not_o within_o they_o wherewith_o to_o recruit_v their_o spirit_n or_o that_o opium_n take_v they_o much_o spend_v and_o tire_v with_o distemper_n cause_n as_o in_o weak_a and_o weary_a people_n a_o most_o profound_a sopor_fw-la which_o not_o recruit_v they_o who_o take_v or_o digest_v no_o sustenance_n they_o must_v rather_o grow_v weak_a and_o weak_a for_o somewhat_o be_v spend_v while_o we_o live_v and_o consequent_o the_o sleep_n or_o sopor_fw-la more_o and_o more_o profound_a till_o they_o sleep_v their_o last_o for_o want_v of_o some_o recruit_v which_o be_v the_o very_a thing_n that_o natural_o lessen_v sleep_n and_o awake_v we_o when_o there_o be_v no_o other_o apparent_a cause_n for_o as_o the_o be_v tire_v and_o want_v of_o recruit_v cause_n sleep_v so_o the_o have_v it_o cause_v wake_v or_o which_o be_v the_o same_o in_o effect_n no_o far_o need_v of_o relaxation_n for_o recruit_n sake_n so_o that_o the_o sensitive_a soul_n fall_v to_o his_o useful_a work_n of_o vigilative_a contraction_n for_o sense_n and_o motion_n sake_n 15._o it_o sometime_o cause_n purge_v which_o happen_v as_o far_o as_o i_o have_v observe_v or_o can_v learn_v only_o when_o it_o be_v give_v in_o a_o good_a quantity_n to_o person_n of_o a_o strong_a digestion_n or_o canine_a appetite_n the_o case_n be_v thus_o when_o person_n that_o be_v of_o a_o strong_a digestion_n take_v a_o resinous_n opiate_n in_o good_a quantity_n they_o do_v in_o great_a measure_n by_o their_o fix_a salt_n at_o stomach_n and_o strong_a digestion_n subdue_v the_o volatility_n of_o the_o opium_n and_o dissolve_v its_o rosin_n which_o then_o as_o acrimonious_a rosin_n or_o vomit_n subdue_v by_o fix_a salt_n use_v to_o do_v cause_v purge_v hence_o it_o be_v that_o it_o general_o if_o not_o always_o purge_v dog_n and_o people_n of_o a_o high_a canine_a appetite_n and_o that_o sometime_o meet_v such_o fix_a salt_n it_o purge_v the_o consumptive_a bartholine_n say_v that_o mandrake_n juice_n purge_v when_o it_o meet_v with_o acrimonious_a fix_a salt_n erastus_n and_o quercelan_n do_v agree_v that_o it_o have_v a_o purgative_n quality_n but_o that_o it_o do_v not_o always_o exert_v it_o 1._o because_o it_o take_v away_o the_o sense_n of_o irritation_n 2._o because_o it_o be_v give_v in_o too_o small_a a_o quantity_n the_o reason_n be_v just_a and_o right_a and_o not_o only_o consistent_a with_o but_o confirm_v what_o i_o say_v note_v that_o this_o be_v not_o intend_v of_o the_o purge_v that_o happen_v after_o the_o declination_n of_o its_o operation_n which_o be_v as_o you_o will_v find_v from_o another_o cause_n therefore_o this_o do_v not_o smell_v of_o the_o opium_n as_o the_o other_o do_v because_o it_o be_v past_a and_o go_v before_o that_o in_o the_o declination_n happen_v of_o which_o more_o in_o its_o proper_a place_n 16._o it_o raise_v and_o revive_v some_o person_n that_o be_v almost_o expire_a in_o two_o case_n one_o be_v when_o such_o as_o have_v be_v use_v to_o take_v it_o be_v even_o expire_a for_o want_n of_o it_o of_o which_o more_o hereafter_o the_o other_o case_n be_v when_o violent_a contraction_n as_o from_o pain_n cold_a vomit_n and_o grievous_a passion_n as_o terror_n etc._n etc._n be_v the_o cause_n that_o people_n be_v almost_o expire_a for_o it_o take_v off_o the_o contraction_n by_o relax_v etc._n etc._n 17._o it_o stay_v very_o long_o at_o stomach_n when_o the_o rosin_n thereof_o stick_v to_o the_o stomach_n and_o be_v there_o detain_v beside_o that_o the_o stomach_n be_v relax_v and_o have_v little_a sense_n or_o motion_n as_o in_o sleep_n do_v not_o soon_o digest_v it_o or_o discharge_v it_o it_o be_v fine_a in_o this_o case_n and_o all_o other_o to_o observe_v how_o sensation_n and_o motion_n go_v hand_n in_o hand_n keep_v equal_a pace_n and_o equal_a proportion_n as_o it_o plain_o must_v be_v by_o the_o principle_n of_o relaxation_n and_o contraction_n which_o i_o have_v state_v and_o prove_v 18._o it_o cause_v stoppage_n of_o urine_n sometime_o especial_o in_o old_a people_n by_o over_o relax_v and_o cause_v a_o kind_n of_o a_o temporary_a palsy_n of_o the_o bladder_n as_o be_v show_v and_o take_v away_o the_o sense_n of_o the_o irritation_n of_o the_o urine_n which_o shall_v contract_v the_o bladder_n to_o squeeze_v it_o out_o by_o which_o mean_v it_o happen_v sometime_o that_o the_o bladder_n come_v to_o be_v so_o over_o extend_v beyond_o its_o due_a tone_n that_o they_o can_v contract_v it_o to_o make_v water_n in_o all_o which_o case_n strong_a contracter_n as_o cold_a terror_n etc._n etc._n immediate_o cure_v they_o the_o very_a put_v the_o scrotum_fw-la to_o the_o edge_n of_o a_o cold_a chamberpot_n have_v effect_v it_o several_a time_n by_o my_o advice_n though_o if_o need_v be_v you_o must_v come_v to_o dash_v of_o cold_a water_n upon_o the_o region_n of_o the_o bladder_n or_o pump_v on_o it_o or_o dip_v in_o it_o etc._n etc._n so_o terror_n and_o cause_v a_o very_a smart_n pain_n especial_o near_o those_o part_n will_v do_v much_o but_o cold_a be_v the_o ready_a and_o best_a remedy_n 19_o it_o sometime_o prove_v dangerous_a after_o great_a hemorrbage_n or_o evacuation_n as_o tapping_n in_o dropsy_n etc._n etc._n because_o the_o relaxation_n hinder_v the_o part_n due_o to_o contract_v upon_o what_o remain_v which_o may_v cause_v great_a mischief_n as_o discontinuation_n of_o motion_n etc._n etc._n thus_o have_v you_o all_o the_o constant_a frequent_a and_o rare_a effect_n of_o opium_n take_v internal_o in_o a_o moderate_a do_v so_o natural_o easy_o plain_o and_o mechanical_o explicate_v that_o people_n may_v in_o my_o judgement_n more_o admire_v how_o all_o fail_v of_o discover_v the_o manner_n of_o their_o production_n than_o that_o i_o find_v it_o as_o man_n be_v apt_a to_o think_v of_o the_o circulation_n of_o the_o blood_n which_o now_o as_o i_o hope_v the_o effect_n of_o opium_n do_v seem_v very_o obvious_a both_o which_o case_n be_v to_o i_o very_o strong_a argument_n of_o a_o be_v that_o rule_n and_o dispose_n darken_v and_o illuminate_v etc._n etc._n as_o he_o please_v when_o i_o consider_v that_o both_o the_o circulation_n of_o the_o blood_n and_o the_o cause_n of_o the_o operation_n of_o opium_n viz._n pleasure_n at_o stomach_n etc._n etc._n fall_v under_o the_o sense_n of_o many_o million_o who_o in_o one_o case_n see_v the_o blood_n move_v and_o in_o the_o other_o feel_v
the_o pleasure_n yet_o be_v neither_o discover_v for_o many_o thousand_o of_o year_n especial_o consider_v also_o that_o in_o the_o case_n of_o opium_n thousand_o of_o ingenious_a man_n have_v diligent_o inquire_v after_o the_o cause_n of_o its_o operation_n who_o make_v no_o far_a step_n in_o it_o then_o to_o state_n thing_n that_o have_v not_o as_o much_o as_o existence_n viz._n a_o cold_a quality_n and_o 〈◊〉_d fly_v from_o the_o stomach_n to_o the_o head_n to_o be_v the_o cause_n thereof_o therefore_o it_o be_v plain_a that_o neither_o be_v he_o that_o plant_n any_o thing_n neither_o he_o that_o water_v but_o god_n that_o give_v the_o increase_n of_o knowledge_n and_o of_o other_o thing_n to_o who_o be_v all_o glory_n chap._n xx._n the_o explication_n of_o the_o effect_n of_o the_o declination_n of_o the_o operation_n of_o opium_n in_o a_o moderate_a do_v 1._o a_o general_n return_v of_o all_o disease_n and_o disaster_n when_o the_o operation_n of_o opium_n be_v over_o because_o it_o do_v not_o as_o be_v show_v operate_v as_o a_o alterative_a but_o a_o please_a diverter_n of_o the_o sensitive_a soul_n for_o some_o time_n during_o which_o it_o cause_v a_o general_a relaxation_n of_o all_o the_o sensile_a part_n whereby_o the_o animal_n spirit_n be_v expanded_a grow_v unfit_a to_o convey_v impression_n smart_o which_o be_v requisite_a to_o cause_v a_o sense_n of_o pain_n etc._n etc._n as_o have_v be_v often_o say_v but_o it_o cure_v several_a distemper_n viz._n such_o as_o please_v and_o comfort_v the_o sensitive_a soul_n compose_v the_o spirit_n relaxation_n perspiration_n sweat_v etc._n etc._n can_v quite_o take_v away_o of_o which_o more_o particular_o when_o we_o come_v to_o speak_v of_o the_o use_n of_o opium_n in_o cure_n 2._o sweat_n happen_v in_o the_o declination_n of_o its_o operation_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v because_o that_o now_o all_o the_o parâ—s_a contract_n which_o by_o their_o relaxation_n suspend_v all_o humour_n during_o its_o operation_n do_v mechanical_o squeeze_v out_o the_o congest_a humour_n there_o be_v less_o room_n in_o the_o body_n as_o be_v say_v of_o sweat_n upon_o awake_v by_o the_o return_n of_o the_o vigilative_a contraction_n after_o relaxation_n during_o the_o sleep_n which_o be_v to_o be_v compare_v to_o the_o relaxation_n during_o the_o operation_n of_o opium_n and_o the_o return_v of_o the_o contraction_n when_o it_o be_v end_v beside_o that_o both_o upon_o the_o go_v off_o of_o the_o operation_n and_o awake_v the_o motion_n of_o the_o heart_n grow_v more_o vigorous_a as_o it_o do_v upon_o motion_n by_o the_o intentive_a contraction_n do_v more_o powerful_o propell_v the_o humour_n out_o at_o the_o pore_n as_o happen_v in_o sweat_n upon_o motion_n 3._o frequent_v make_v of_o water_n happen_v partly_o by_o the_o titillation_n of_o the_o volatile_a salt_n as_o by_o cantharides_n etc._n etc._n that_o be_v now_o separate_v from_o the_o blood_n partly_o by_o the_o contraction_n of_o the_o whole_a body_n squeese_v it_o out_o at_o the_o kidney_n as_o when_o people_n be_v cold_a they_o make_v more_o water_n for_o that_o reason_n 4._o a_o looseness_n may_v and_o do_v happen_v sometime_o from_o the_o like_a contraction_n squeese_v out_o the_o humour_n that_o be_v suspend_v during_o the_o relaxation_n by_o the_o opium_n which_o be_v common_a for_o such_o contraction_n to_o cause_n as_o by_o cold_a terror_n etc._n etc._n and_o because_o sensation_n grow_v more_o nice_a and_o irritable_a by_o the_o humour_n by_o reason_n of_o the_o contraction_n which_o be_v the_o more_o for_o the_o grievance_n of_o fail_v of_o the_o pleasure_n of_o opium_n therefore_o 5._o disease_n pain_n etc._n etc._n seem_v worse_o upon_o the_o return_n of_o the_o grievance_n because_o of_o the_o great_a ease_n they_o have_v during_o the_o operation_n of_o the_o opium_n contraria_fw-la inter_fw-la se_fw-la magis_fw-la elucescunt_fw-la and_o it_o be_v particular_o observe_v of_o pleasure_n that_o it_o leave_v man_n worse_o than_o it_o find_v they_o thus_o a_o man_n be_v worse_a more_o sad_a etc._n etc._n post_fw-la coitum_fw-la more_o melancholy_a after_o all_o sort_n of_o pleasure_n insomuch_o that_o it_o be_v grow_v to_o a_o proverb_n viz._n after_o merry_a come_v sorry_a or_o after_o mirth_n come_v sorrow_n as_o also_o minus_n gaudebis_fw-la minus_fw-la dolebis_fw-la therefore_o 6._o melaneholy_n do_v often_o if_o not_o always_o happen_v in_o some_o degree_n after_o its_o operation_n be_v end_v 1._o because_o of_o the_o return_n of_o the_o contraction_n or_o toil_n of_o the_o sensitive_a soul_n 2._o because_o as_o be_v say_v the_o sense_n of_o pleasure_n new_o lose_v aggravate_v the_o sorrow_n as_o have_v be_v show_v after_o coition_n etc._n etc._n 7._o the_o pulse_n be_v narrow_a because_o the_o contraction_n return_v with_o melancholy_a and_o return_v of_o disaster_n improve_v when_o that_o so_o happen_v as_o it_o general_o do_v 8._o itch_a of_o the_o skin_n happen_v about_o this_o time_n because_o that_o now_o the_o volatile_a salt_n which_o cause_v tuillation_n be_v arrive_v as_o far_o as_o the_o skin_n upon_o its_o march_n out_o of_o the_o body_n chap._n xxi_o the_o explication_n of_o the_o effect_n of_o opium_n in_o a_o excessive_a do_v the_o cause_n of_o most_o of_o these_o effect_n will_v be_v evident_a from_o the_o explication_n of_o the_o former_a because_o the_o difference_n be_v only_o in_o the_o quantity_n of_o the_o opium_n therefore_o i_o be_o often_o necessitate_v to_o speak_v much_o the_o same_o as_o i_o have_v do_v before_o you_o can_v expect_v any_o good_a effect_n from_o its_o excess_n any_o more_o than_o you_o have_v from_o wine_n though_o the_o best_a of_o cordial_n next_o to_o the_o sal._n volatile_a oleosum_fw-la of_o opium_n but_o rather_o less_o because_o opium_n be_v join_v to_o a_o pernicious_a rosin_n which_o you_o may_v be_v sure_o will_v be_v very_o grievous_a to_o the_o stomach_n in_o great_a quantity_n if_o it_o be_v so_o in_o little_a the_o evil_a effect_n in_o this_o case_n do_v main_o proceed_v either_o from_o too_o much_o relaxation_n as_o in_o drunkenness_n or_o from_o the_o rosin_n at_o stomach_n 1._o a_o heat_n at_o stomach_n be_v cause_v by_o the_o intense_a heat_n of_o the_o opium_n in_o a_o great_a quantity_n it_o be_v sensible_o a_o very_a hot_a thing_n 2._o the_o sense_n of_o weight_n at_o stomach_n be_v cause_v by_o the_o great_a relaxation_n that_o it_o cause_n which_o render_v the_o stomach_n proportionable_o weak_a and_o unable_a to_o endeavour_v its_o own_o relief_n so_o that_o the_o rosin_n etc._n etc._n lie_v heavy_a upon_o it_o thus_o we_o find_v a_o great_a heaviness_n at_o stomach_n when_o any_o thing_n grieve_v it_o that_o it_o can_v reject_v or_o discharge_v 3._o gaity_n of_o humour_n be_v cause_v at_o first_o as_o by_o the_o pleasure_n of_o a_o great_a quantity_n of_o wine_n by_o its_o please_a agreeableness_n to_o the_o membrane_n at_o stomach_n till_o the_o relaxation_n grow_v enormous_a as_o by_o a_o great_a do_v of_o wine_n sudden_o drink_v to_o which_o it_o be_v very_o like_a in_o all_o its_o effect_n except_o such_o as_o proceed_v from_o the_o rosin_n stick_v at_o stomach_n which_o wine_n have_v not_o 4._o sardonick_a laughter_n be_v cause_v as_o you_o see_v in_o drunken_a people_n when_o they_o be_v disable_v by_o the_o great_a relaxation_n that_o they_o can_v well_o express_v themselves_o by_o the_o fail_a tongue_n they_o endeavour_v it_o by_o a_o silly_a kind_n of_o feign_a or_o make_v laughter_n as_o they_o call_v it_o while_o the_o please_a titillation_n at_o stomach_n much_o incline_v they_o to_o mirth_n if_o they_o know_v how_o to_o manage_v and_o carry_v it_o on_o 5._o laxity_n and_o consequent_o debility_n of_o all_o part_n be_v cause_v by_o the_o extraordinary_a relaxation_n of_o they_o by_o a_o continual_a and_o permanent_a sense_n of_o pleasure_n which_o happen_v considerable_o in_o the_o momentary_a pleasure_n of_o venus_n much_o more_o in_o this_o continual_a and_o last_a pleasure_n when_o a_o great_a do_v make_v it_o intense_a as_o in_o drunkenness_n 6._o alienation_n of_o the_o mind_n be_v cause_v as_o in_o drunkenness_n by_o a_o over_o relaxation_n of_o the_o brain_n and_o its_o membrane_n 7._o loss_n of_o memory_n happen_v by_o the_o same_o mean_n as_o in_o drunkenness_n so_o 8._o darkness_n of_o eye_n be_v cause_v by_o a_o relaxation_n of_o the_o coat_n and_o membrane_n of_o the_o eye_n but_o main_o by_o the_o expansion_n of_o the_o animal_n spirit_n by_o that_o relaxation_n which_o as_o in_o sleep_n render_v they_o unfit_a to_o convey_v the_o impression_n of_o light_n etc._n etc._n 9_o laxity_n of_o the_o cornea_n be_v from_o the_o same_o relaxation_n 10._o appearance_n of_o various_a colour_n happen_v by_o as_o be_v say_v the_o unevenness_n of_o the_o cornea_n etc._n etc._n when_o so_o relax_v whereas_o when_o it_o be_v due_o
proclaim_v their_o ignorance_n and_o glory_v in_o their_o great_a shame_n and_o disgrace_n of_o mankind_n that_o humane_a species_n shall_v have_v any_o such_o unthinking_a brute_n in_o it_o iv_o we_o must_v not_o use_v acid_n in_o the_o preparation_n thereof_o 1._o because_o be_v in_o their_o nature_n opposite_a to_o volatile_a salt_n it_o can_v be_v do_v without_o injury_n to_o the_o sal-volatile-oleosum_a of_o opium_n 2._o because_o they_o can_v so_o well_o agree_v with_o the_o oily_a part_n of_o it_o yet_o be_v they_o not_o so_o much_o to_o be_v blame_v as_o extract_n make_v in_o spirit_n of_o wine_n or_o sulphureous_a menstruum_n because_o acid_a menstruum_n leave_v the_o rosin_n behind_o they_o untouched_a or_o not_o extract_v v._o a_o salino-volatile_a menstruum_fw-la as_o spirit_n of_o sal_fw-la ammoniac_a of_o urine_n etc._n etc._n be_v not_o so_o proper_a 1._o it_o may_v render_v the_o sal-volatile-oleosum_a of_o opium_n too_o acrimonious_a 2._o because_o by_o its_o volatility_n acrimony_n etc._n etc._n it_o may_v cause_v too_o great_a a_o stir_n in_o the_o blood_n etc._n etc._n and_o so_o oppose_v or_o hinder_v sleep_n which_o be_v one_o of_o the_o most_o happy_a and_o useful_a effect_n of_o opium_n or_o it_o be_v sal-volatile-oleosum_a 3._o because_o it_o may_v have_v undue_a effect_n by_o alter_v its_o general_a disposition_n nay_o vi_o we_o be_v not_o to_o use_v a_o lixivial_a menstruum_fw-la though_o so_o much_o cry_v up_o 1._o because_o it_o extract_v the_o resinous_a part_n which_o experto_fw-la crede_fw-la roberto_n i_o have_v find_v to_o be_v pernicious_a upon_o that_o account_n like_o extract_n in_o spirit_n of_o wine_n unless_o great_a care_n be_v take_v to_o separate_v those_o part_n which_o be_v not_o easy_o do_v by_o filtration_n etc._n etc._n 2._o because_o be_v very_o apt_a to_o join_v with_o the_o oily_a part_n and_o quite_o to_o destroy_v their_o nature_n by_o convert_v it_o into_o a_o kind_n of_o sapo_n it_o may_v deal_v so_o with_o some_o of_o the_o oily_a part_n of_o the_o sal-volatile-oleosum_a of_o opium_n 3._o because_o there_o be_v no_o need_n to_o run_v any_o of_o these_o hazard_n since_o the_o sal-volatile-oleosum_a may_v be_v as_o i_o shall_v show_v easy_o extract_v in_o its_o purity_n without_o those_o trouble_n and_o danger_n 4._o because_o any_o tincture_n make_v thus_o be_v apt_a to_o let_v go_v the_o rosin_n at_o stomach_n if_o it_o be_v dilute_v with_o aqueous_a moisture_n take_v before_o with_o it_o or_o after_o it_o which_o so_o be_v let_v go_v coalesces_fw-la and_o do_v mischief_n vii_o the_o use_n of_o fire_n any_o way_n beside_o that_o of_o its_o torrefaction_n be_v much_o to_o be_v suspect_v 1._o because_o the_o sal-volatile-oleosum_a may_v be_v in_o some_o measure_n thereby_o evaporate_v or_o 2._o an_fw-mi empyreum_fw-la contract_v and_o 3._o the_o rosin_n as_o be_v say_v of_o its_o torrefaction_n grow_v the_o more_o in_o proportion_n if_o any_o of_o the_o sal-volatile-oleosum_a or_o but_o the_o phlegm_n be_v by_o that_o mean_n evaporate_v and_o the_o remainder_n keep_v for_o use_v and_o particular_o viii_o the_o distillation_n thereof_o may_v cause_v mighty_a alteration_n in_o its_o property_n strength_n etc._n etc._n we_o must_v therefore_o avoid_v all_o these_o way_n of_o prepare_v it_o and_o yet_o must_v we_o 1._o separate_a the_o sal-volatile-oleosum_a of_o opium_n from_o all_o its_o rosin_n earth_n filth_n and_o dross_n 2._o no_o way_n weaken_v it_o alter_v it_o or_o add_v new_a quality_n thereto_o but_o preserve_v this_o most_o noble_a and_o inestimable_a medicament_n in_o its_o purity_n and_o sincerity_n to_o this_o end_n rain_n water_v distil_v use_v cold_a answer_v all_o intent_n for_o 1._o it_o ready_o imbibe_v the_o sal-volatile-oleosum_a of_o opium_n without_o fire_n heat_v lixivial_a salt_n as_o salt_n of_o tartar_n etc._n etc._n 2._o it_o imbibe_v none_o of_o the_o rosin_n of_o the_o opium_n but_o let_v it_o all_o subside_n together_o with_o the_o earthy_a and_o drossy_a part_n separate_v the_o light_a filth_n if_o there_o be_v any_o to_o the_o surface_n 3._o it_o no_o way_n weaken_v alter_v or_o add_v any_o new_a quality_n to_o the_o sal-volatile-oleosum_a 4._o whatever_o cold_a water_n dissolve_v which_o be_v the_o general_n drink_v or_o menstruum_fw-la appoint_v by_o the_o alwise_a creater_n for_o the_o dissolution_n of_o all_o thing_n take_v into_o the_o stomach_n of_o animal_n be_v easy_o dissolve_v at_o stomach_n by_o its_o more_o powerful_a and_o agreeable_a menstruum_fw-la and_o not_o only_o so_o but_z 5._o water_n itself_o be_v a_o mighty_a stomachick_n and_o causer_n of_o digestion_n as_o hypocrates_n positive_o declare_v l._n 6._o epidem_fw-la sect._n 4._o but_o there_o be_v no_o need_n of_o quote_v hypocrates_n in_o so_o notorious_a a_o thing_n daily_a experience_n tell_v we_o the_o same_o do_v not_o all_o animal_n by_o its_o help_n digest_v their_o food_n do_v not_o all_o mineral_n water_n scarce_o any_o except_v create_v a_o appetite_n and_o cause_n digestion_n even_o when_o no_o such_o effect_n can_v be_v attribute_v to_o the_o mineral_n they_o contain_v than_o which_o they_o do_v also_o as_o may_v be_v very_o easy_o prove_v more_o good_a general_o speak_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d for_o which_o and_o many_o more_o reason_n it_o be_v great_a neglect_n and_o folly_n that_o it_o be_v not_o more_o use_v for_o extract_n etc._n etc._n for_o then_o they_o ready_o dissolve_v at_o stomach_n and_o thereby_o 〈◊〉_d and_o speedy_o take_v effect_n give_v it_o the_o least_o 〈◊〉_d and_o disturbance_n that_o may_v be_v as_o be_v experimental_o find_v in_o that_o of_o aloe_n scammony_n briony_n 〈◊〉_d agariâ—_n 〈◊〉_d coloquintida_n sena_n and_o what_o not_o unless_o the_o virtue_n lie_v in_o the_o resinous_a parâ—s_n for_o then_o sulphureous_a or_o lixivial_a menstruum_n be_v convenient_a how_o inconvenient_a be_v they_o then_o when_o the_o evil_a or_o mischief_n lie_v therein_o as_o in_o our_o case_n 6._o it_o be_v not_o to_o be_v doubt_v but_o water_n general_o imbibe_v what_o be_v best_a and_o most_o agreeable_a to_o our_o body_n it_o be_v the_o general_n menstruum_fw-la appoint_v by_o wisdom_n itself_o for_o that_o use_v and_o to_o be_v the_o vehicle_n of_o what_o be_v best_a in_o all_o our_o food_n etc._n etc._n to_o the_o blood_n however_o there_o can_v be_v no_o doubt_n of_o what_o main_o concern_v we_o at_o present_a its_o most_o ready_a dissolve_v our_o panacea_fw-la in_o the_o stomach_n that_o do_v it_o out_o of_o it_o when_o cold_a without_o the_o convenient_a digestive_a heat_n and_o powerful_a menstruum_fw-la that_o it_o find_v there_o therefore_o take_v of_o distil_a rain-water_n 24_o ounce_n of_o choice_a opium_n slice_v thin_a 8_o ounce_n put_v they_o together_o in_o a_o strong_a glass_n vessel_n of_o bottle-metal_n that_o contain_v about_o 3_o piâ—ts_n let_v it_o be_v of_o a_o tall_a figure_n with_o a_o mouth_n that_o convenient_o receive_v a_o cork_n a_o large_a glass_n bottle_n may_v serve_v the_o turn_n cork_n it_o so_o as_o the_o cork_n may_v be_v easy_o take_v out_o shake_v it_o 3_o or_o 4_o time_n a_o day_n for_o 6_o day_n and_o keep_a it_o in_o a_o place_n free_a from_o frost_n or_o any_o very_a sensible_a degree_n of_o heat_n which_o be_v perform_v lie_v the_o vessel_n side-long_a for_o 24_o hour_n long_o and_o afterward_o decant_v and_o filter_n your_o tincture_n which_o will_v be_v of_o a_o ruby_n colour_n and_o put_v it_o into_o a_o glass_n bottle_n of_o such_o a_o bigness_n as_o that_o it_o may_v fill_v it_o within_o a_o small_a matter_n of_o the_o cork_n and_o so_o let_v it_o stand_v for_o 3_o or_o 4_o day_n then_o poâ—r_v off_o some_o of_o the_o surface_n of_o it_o and_o instead_o thereof_o put_v sweet_a oil_n thereon_o let_v the_o vessel_n have_v a_o convenient_a dust_n or_o pipe_n in_o the_o side_n thereof_o to_o empty_v it_o out_o upon_o occasion_n this_o i_o call_v the_o liquid_a panacea_fw-la of_o opium_n to_o the_o faeces_fw-la add_v a_o pint_n of_o cold_a distil_a water_n shake_v the_o vessel_n as_o before_o 3_o or_o 4_o time_n in_o the_o day_n let_v it_o stand_v on_o it_o 24_o hour_n and_o in_o the_o morning_n decant_v it_o into_o another_o vessel_n repeat_v the_o same_o quantity_n of_o distil_a rain-water_n till_o the_o opium_n no_o long_o tinge_v it_o or_o very_o inconsiderable_o in_o 24_o hour_n at_o last_o you_o may_v use_v water_n keep_v hot_a by_o a_o fire_n &c_n &c_n the_o better_a to_o extract_v the_o remain_v sal-volatile-oleosum_a evaporate_v all_o these_o last_o water_n in_o balneo_fw-la to_o the_o consistence_n of_o a_o extract_n this_o i_o call_v the_o solid_a panacea_fw-la of_o opium_n god_n and_o nature_n act_v by_o simple_a mean_n and_o nothing_o in_o imitation_n of_o they_o be_v more_o commendable_a in_o a_o medicament_n than_o simplicity_n therefore_o i_o shall_v add_v nothing_o to_o the_o panacea_n but_o whole_o
leave_v that_o to_o other_o physician_n to_o please_v themselves_o or_o patient_n by_o add_v ambergrise_n musk_n saffron_n oil_n of_o cinnamon_n or_o other_o chemical_a oil_n sugar_n or_o the_o like_a according_a to_o their_o intent_n i_o have_v observe_v that_o as_o reason_n tell_v we_o its_o smell_n be_v best_a palliate_v by_o other_o rank_n smell_v as_o that_o of_o onion_n garlic_n asa-foetida_a etc._n etc._n and_o its_o bitter_a taste_n with_o bitter_a thing_n as_o gentian_n centaury_n etc._n etc._n therefore_o when_o person_n that_o know_v its_o smell_n and_o taste_n be_v aver_v to_o take_v it_o if_o the_o other_o more_o acceptable_a thing_n will_v not_o suffice_v for_o that_o purpose_n use_v some_o of_o these_o you_o may_v when_o you_o be_v in_o haste_n infuse_v half_o a_o dozen_o slice_n of_o gentian-root_n and_o one_o slice_v of_o a_o onion_n or_o a_o bruise_a clove_n of_o garlic_n or_o both_o in_o a_o glass_n of_o wine_n for_o one_o hour_n for_o a_o vehicle_n in_o that_o case_n it_o be_v better_o to_o infuse_v they_o long_o if_o you_o have_v time_n but_o you_o will_v find_v that_o the_o liquid_a panacea_fw-la have_v not_o such_o a_o mighty_a rank_a taste_n or_o smell_v but_o that_o it_o be_v easy_o palliate_v by_o such_o mean_n if_o the_o opium_n have_v no_o empyreum_fw-la the_o solid_a panacea_fw-la may_v be_v also_o palliate_v by_o the_o same_o thing_n convenient_o mix_v therewith_o i_o know_v there_o be_v other_o way_n and_o mean_n to_o separate_v the_o rosin_n etc._n etc._n as_o extract_v a_o tincture_n of_o opium_n in_o spirit_n of_o wine_n and_o afterward_o precipitate_v the_o rosin_n with_o distil_a rain-water_n but_o this_o be_v attend_v with_o more_o trouble_n and_o many_o inconvenience_n that_o be_v avoid_v by_o the_o cold_a distil_a rain-water_n for_o 1._o you_o know_v not_o how_o the_o spirit_n of_o wine_n may_v as_o be_v say_v alter_v it_o 2._o this_o be_v go_v round_o the_o bush_n and_o compound_v two_o menstruum_n together_o whereas_o the_o simple_a water_n use_v alone_o be_v much_o better_a 3._o you_o can_v thus_o separate_v the_o resinous_a particle_n so_o perfect_o by_o reason_n that_o the_o spirit_n of_o wine_n must_v retain_v some_o of_o they_o and_o if_o you_o add_v more_o and_o more_o water_n in_o the_o precipitation_n the_o tincture_n become_v too_o much_o dilute_v and_o very_o weak_a how_o much_o better_a be_v it_o to_o use_v a_o menstruum_fw-la that_o never_o take_v up_o any_o rosin_n and_o consequent_o need_v no_o such_o separation_n and_o labour_n of_o precipitation_n it_o be_v better_a not_o to_o admit_v a_o enemy_n to_o one_o country_n than_o afterward_o to_o endeavour_v his_o expulsion_n for_o he_o will_v at_o best_a leave_n some_o mark_n of_o his_o hostility_n behind_o he_o as_o the_o rosin_n will_v in_o the_o spirit_n of_o wine_n the_o like_a inconvenience_n there_o will_v be_v in_o separate_v it_o by_o the_o way_n of_o distillation_n as_o 1._o the_o alter_n of_o it_o by_o the_o tyranny_n of_o fire_n 2._o the_o loss_n of_o it_o by_o evaporation_n 3._o the_o addition_n of_o the_o particle_n of_o fire_n thereto_o 4._o the_o never_o separate_a it_o so_o well_o that_o way_n 5._o the_o disunit_a of_o the_o oil_n and_o volatile_a salt_n in_o some_o measure_n but_o what_o experience_n may_v hereafter_o teach_v man_n i_o will_v not_o determine_v neither_o can_v 1_n but_o this_o i_o can_v that_o as_o it_o be_v even_o miraculous_a that_o people_n shall_v never_o mind_v the_o cause_n they_o daily_o feel_v and_o solicitous_o seek_v for_o so_o it_o be_v as_o strange_a that_o they_o can_v not_o hit_v upon_o the_o plain_a use_n of_o water_n so_o very_o common_a in_o all_o hand_n for_o a_o menstruum_fw-la either_o by_o chance_n or_o consideration_n in_o all_o the_o eastern_a part_n of_o the_o world_n where_o it_o be_v so_o universal_o take_v or_o in_o the_o inquisitive_a western_a part_n of_o the_o world_n where_o it_o have_v be_v study_v and_o consider_v by_o great_a number_n with_o the_o utmost_a diligence_n but_o they_o pass_v over_o water_n as_o despicable_a because_o common_a for_o familiarity_n breed_v contempt_n though_o its_o be_v make_v the_o drink_n of_o all_o live_a creature_n by_o the_o omniscient_n shall_v commend_v it_o above_o all_o thing_n do_v like_o those_o that_o regardless_o pass_v over_o a_o jewel_n or_o treasure_n and_o have_v once_o leave_v it_o behind_o they_o proceed_v far_o and_o far_o from_o it_o the_o great_a progress_n they_o make_v conclude_v that_o it_o be_v not_o to_o be_v find_v the_o way_n they_o pass_v not_o because_o it_o be_v not_o there_o but_o because_o they_o can_v not_o see_v it_o as_o for_o the_o keep_n of_o the_o liquid_a panacea_fw-la uncorrupted_a i_o do_v not_o find_v it_o apt_a to_o change_v however_o because_o make_v so_o easy_o by_o bare_a throw_v it_o into_o water_n it_o need_v not_o be_v keep_v long_o but_o may_v be_v make_v upon_o all_o occasion_n or_o at_o least_o one_o under_o the_o other_o as_o the_o apothecary_n spend_v it_o who_o it_o be_v not_o improbable_a may_v by_o their_o great_a ingenuity_n and_o experience_n in_o those_o matter_n find_v other_o convenient_a mean_n to_o preserve_v it_o for_o their_o purpose_n chap._n xxvi_o of_o other_o preparation_n of_o opium_n that_o be_v absolute_o or_o tolerable_o safe_a in_o a_o moderate_a do_v i._o all_z preparation_n be_v very_o safe_a in_o a_o moderate_a do_v wherein_o the_o resinous_a part_n of_o the_o opium_n be_v whole_o separate_v from_o it_o such_o be_v all_o extract_v make_v in_o aqueous_a menstruum_n or_o any_o other_o that_o imbibe_v none_o of_o the_o resinous_a part_n of_o opium_n as_o the_o preparation_n that_o wedâ—lius_n have_v in_o his_o opiologia_fw-la l._n 1._o sect._n 2._o cap._n 5._o p._n 65._o which_o be_v extract_v out_o of_o phlegm_n of_o vinegar_n that_o remain_v after_o the_o preparation_n of_o arcanum_n tartari_fw-la so_o laudanum_n liquidum_fw-la cydoniatum_n and_o langelott_n laudanum_n if_o the_o resinous_a part_n be_v due_o separate_v be_v very_o safe_a and_o commendable_a for_o the_o like_a reason_n as_o be_v also_o le_fw-fr mort's_n extract_n out_o of_o rain-water_n diacodium_fw-la etc._n etc._n ii_o all_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n though_o not_o separate_v from_o it_o be_v so_o alter_v order_v divide_v etc._n etc._n as_o not_o to_o stick_v to_o the_o stomach_n and_o render_v digestible_a and_o passable_a out_o of_o it_o without_o offence_n may_v be_v safe_o use_v of_o this_o kind_n there_o be_v or_o may_v be_v two_o sort_n first_o such_o wherein_o the_o nature_n of_o the_o rosin_n be_v alter_v in_o some_o degree_n at_o least_o second_o such_o wherein_o though_o the_o nature_n of_o the_o rosin_n be_v not_o destroy_v yet_o be_v it_o so_o order_v divide_a etc._n etc._n as_o not_o to_o stick_v to_o the_o stomach_n but_o render_v digestible_a and_o passable_a without_o offence_n of_o the_o first_o sort_n be_v 1._o such_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n be_v quite_o alter_v in_o its_o form_n and_o nature_n by_o chemistry_n or_o artificial_a torture_n of_o fire_n which_o because_o hardly_o to_o be_v do_v without_o much_o impair_n the_o sal-volatile-oleosum_a will_v be_v neither_o commendable_a nor_o worth_a while_n consider_v how_o easy_o without_o that_o trouble_v pain_n and_o labour_n even_o the_o rosin_n itself_o may_v be_v separate_v whole_o from_o the_o opium_n by_o aqueous_a menstruum_n 2._o such_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n be_v alter_v and_o as_o it_o be_v soapify_v by_o lixivial_a salt_n or_o soap_n which_o ready_o engage_v and_o intimate_o join_v with_o the_o small_a resinous_a particle_n of_o the_o opium_n by_o long_a and_o strong_a pound_v they_o together_o in_o a_o mortar_n or_o otherwise_o as_o in_o matthew_n or_o starkey_n pill_n bates's_fw-fr pacifick_n pill_n etc._n etc._n by_o which_o mean_v those_o resinous_a particle_n become_v in_o a_o great_a degree_n at_o least_o if_o not_o whole_o miscible_a with_o and_o so_o dissolvable_a and_o digestible_a in_o the_o liquor_n we_o drink_v and_o easy_o subduable_a by_o the_o menstruum_fw-la at_o stomach_n out_o of_o which_o it_o also_o easy_o pass_v by_o reason_n of_o the_o great_a slipperiness_n it_o acquire_v which_o also_o prevent_v its_o stick_n by_o that_o intimate_a mixture_n with_o the_o soap_n or_o lixivial_n therefore_o i_o take_v those_o pill_n of_o matthews_n and_o dr._n bates_n to_o be_v safe_a preparation_n though_o not_o to_o be_v compare_v to_o the_o panacea_fw-la wherein_o all_o danger_n and_o its_o cause_n be_v quite_o take_v away_o by_o whole_o separate_v the_o resinous_a part_n earth_n and_o filth_n of_o the_o opium_n from_o its_o sal-volatile-oleosum_a and_o doubtless_o have_v maththews_n starkey_n and_o bates_n know_v that_o the_o rosin_n of_o opium_n have_v be_v the_o cause_n of_o its_o ill_a effect_n they_o will_v never_o
darkness_n of_o the_o eye_n see_v thing_n double_a various_a colour_n before_o the_o eye_n loss_n of_o feel_v ease_n from_o pain_n etc._n etc._n deadness_n of_o the_o eye_n to_o the_o view_n dilatation_n of_o the_o pupilla_fw-la efflorescence_n of_o the_o skin_n laxity_n of_o the_o low_a jaw_n intumescence_n and_o laxity_n of_o the_o lip_n falter_v of_o the_o tongue_n sardonick_a laughter_n laxity_n and_o weakness_n of_o all_o part_n a_o general_a ineptitude_n to_o motion_n failure_n in_o make_v water_n go_v to_o stool_n and_o in_o all_o thing_n that_o require_v strength_n contraction_n motion_n etc._n etc._n difficulty_n of_o breathe_v a_o wide_a and_o slow_a pulse_n a_o condition_n in_o general_a very_a like_o that_o of_o drunkenness_n which_o also_o proceed_v from_o relaxation_n second_o when_o you_o be_v satisfy_v that_o relaxation_n be_v the_o cause_n use_v all_o mean_n to_o procure_v a_o due_a contraction_n of_o all_o part_n which_o be_v to_o be_v do_v 1._o by_o remove_v the_o cause_n of_o the_o relaxation_n 2._o by_o use_v all_o good_a mean_n for_o contraction_n first_o therefore_o give_v a_o brisk_a quick_a and_o strong_a vomit_n both_o to_o discharge_v the_o opiate_n and_o cause_n contraction_n of_o part_n by_o a_o grievous_a sensation_n proportion_n it_o to_o the_o deadness_n stupidity_n or_o sleepiness_n of_o the_o person_n so_o as_o to_o give_v it_o of_o twice_o the_o ordinary_a strength_n of_o vomit_n in_o case_n there_o be_v great_a danger_n from_o those_o symptom_n and_o that_o they_o be_v of_o a_o high_a nature_n after_o the_o person_n have_v vomit_v 3_o or_o 4_o time_n or_o so_o often_o as_o that_o you_o may_v judge_v the_o stomach_n well_o clear_v of_o the_o opiate_n give_v half_o a_o ounce_n of_o cream_n of_o tartar_n fine_o powder_v in_o thin_a broth_n whey_n water_n small_a beer_n or_o any_o convenient_a liquid_a which_o will_v correct_v the_o opiate_n if_o any_o remain_v at_o stomach_n turn_v the_o vomit_n to_o a_o purger_n to_o clear_v the_o intestine_n also_o and_o contribute_v much_o to_o the_o contraction_n of_o part_n which_o you_o must_v always_o have_v in_o your_o thought_n as_o the_o roll_a intention_n in_o this_o case_n therefore_o second_o you_o must_v use_v contracter_n all_o the_o time_n the_o chief_a of_o which_o be_v cold_a grievous_a sensation_n or_o pain_n terror_n fear_v voluntary_a motion_n and_o acid_n which_o last_n can_v be_v so_o well_o use_v during_o the_o vomit_v lest_o they_o stop_v it_o therefore_o especial_o if_o the_o person_n be_v very_o stupid_a keep_v he_o very_o cold_a for_o he_o will_v hardly_o feel_v it_o nor_o take_v cold_a because_o the_o relaxation_n and_o the_o insensibleness_n of_o grievance_n by_o cold_a etc._n etc._n keep_v the_o pore_n open_a let_v he_o be_v if_o possible_a in_o some_o motion_n as_o walk_v hew_v saw_v knock_v tug_v etc._n etc._n the_o more_o violent_a it_o be_v the_o better_a because_o it_o cause_v more_o contraction_n and_o agitation_n to_o prevent_v sopor_n to_o force_v he_o to_o motion_n if_o need_v be_v prick_a pinch_a or_o whip_v he_o about_o the_o leg_n etc._n etc._n will_v be_v of_o good_a use_n because_o grievous_a sensation_n add_v defensive_a contraction_n which_o be_v the_o great_a sort_n to_o that_o of_o the_o intentive_a contraction_n by_o voluntary_a motion_n these_o mean_n fail_v he_o shall_v be_v expose_v stark_o naked_a to_o the_o cold_a air_n and_o in_o desperate_a case_n throw_v sudden_o at_o unaware_o into_o cold_a water_n by_o which_o mean_v you_o cause_n terror_n surprise_v and_o cold_a which_o be_v the_o high_a and_o most_o forcible_a contracter_n to_o conspire_v to_o the_o contraction_n of_o part_n hence_o it_o be_v that_o drunken_a people_n who_o be_v so_o from_o relaxation_n become_v sober_a as_o in_o a_o moment_n by_o that_o mean_n all_o the_o time_n but_o during_o the_o vomit_v let_v he_o use_v cold_a acid_n in_o great_a plenty_n and_o very_o manifest_o acid_a for_o they_o will_v not_o only_o contribute_v to_o contraction_n but_o very_o much_o correct_v the_o opiate_n to_o this_o end_n juice_n of_o orange_n or_o lemon_n verjuice_n or_o water_n acidulate_v to_o a_o good_a degree_n by_o verjuice_n vinegar_n juice_n of_o lemon_n spirit_n of_o vitriol_n sulphur_n or_o the_o like_a will_v be_v very_o proper_a where_o you_o have_v not_o the_o convenience_n to_o plunge_v they_o into_o cold_a water_n as_o be_v direct_v dash_v or_o pump_v very_o cold_a water_n or_o water_n with_o a_o four_o part_n of_o vinegar_n upon_o their_o naked_a body_n will_v be_v of_o great_a use_n especial_o if_o surprise_o do_v to_o cause_v the_o more_o terror_n and_o concern_v these_o thing_n may_v be_v do_v more_o or_o lâ—ss_o as_o cause_n may_v require_v which_o must_v be_v leave_v to_o the_o discretion_n of_o the_o present_a physician_n or_o friend_n and_o standard_n by_o in_o case_n there_o be_v no_o physician_n i_o only_o caution_n that_o contracter_n shall_v not_o be_v use_v too_o spare_o and_o that_o you_o shall_v never_o cease_v to_o advance_v in_o the_o use_n of_o they_o till_o you_o perceive_v their_o good_a effect_n and_o then_o to_o continue_v they_o as_o occasion_n require_v note_v that_o the_o case_n may_v well_o happen_v that_o the_o rosin_n may_v stick_v at_o stomach_n and_o yet_o no_o sign_n or_o symptom_n appear_v but_o those_o of_o relaxation_n by_o reason_n that_o the_o feel_n at_o stomach_n may_v thereby_o be_v disable_v to_o take_v any_o notice_n of_o it_o to_o be_v sure_a of_o this_o you_o have_v no_o other_o mean_n because_o the_o symptom_n and_o effect_n of_o grievous_a sensation_n can_v appear_v where_o it_o be_v not_o for_o the_o aforesaid_a reason_n but_o to_o examine_v whether_o the_o opiate_n be_v a_o resinous_a one_o as_o crude_a opium_n extract_v out_o of_o spirit_n of_o wine_n or_o the_o like_a for_o than_o you_o may_v conclude_v especial_o if_o they_o be_v give_v in_o a_o massy_a solid_a form_n as_o that_o of_o pill_n etc._n etc._n without_o sever_n the_o particle_n of_o the_o rosin_n by_o other_o thing_n as_o the_o yolk_n of_o a_o egg_n etc._n etc._n that_o the_o rosin_n may_v in_o all_o probability_n stick_v at_o stomach_n though_o its_o symptom_n do_v not_o appear_v for_o the_o aforesaid_a reason_n in_o such_o a_o case_n the_o best_a advice_n that_o i_o can_v give_v be_v external_o to_o use_v all_o contract_n mean_v as_o be_v direct_v and_o internal_o the_o mean_v prescribe_v for_o dissolution_n of_o the_o rosin_n for_o you_o will_v thereby_o answer_v both_o intention_n failure_n of_o make_v water_n often_o happen_v in_o these_o case_n which_o you_o may_v general_o help_v by_o only_o clap_v the_o scrotum_fw-la to_o the_o cold_a chamber_n pot_n or_o into_o cold_a water_n and_o if_o that_o will_v not_o do_v put_v some_o vinegar_n into_o the_o water_n and_o that_o fail_v he_o must_v be_v strip_v and_o cold_a water_n pump_v or_o dash_v upon_o the_o region_n of_o the_o bladder_n iii_o to_o cure_v the_o ill_a effect_n of_o a_o long_a and_o lavish_a use_n of_o opium_n these_o effect_n as_o you_o may_v easy_o observe_v if_o you_o take_v a_o view_n of_o they_o where_o they_o be_v enumerate_v in_o chap._n 6._o be_v either_o 1._o from_o a_o overmuch_o and_o habitual_a relaxation_n of_o part_n as_o weakness_n a_o moapish_a disposition_n diminution_n of_o appetite_n weakness_n of_o digestion_n dropsy_n weakness_n of_o memory_n etc._n etc._n or_o 2._o from_o acrimony_n as_o frequent_a irritation_n to_o make_v water_n priapism_n erection_n of_o the_o penis_n fruitless_a inclination_n to_o venery_n etc._n etc._n in_o this_o case_n as_o in_o that_o of_o old_a drunkard_n which_o be_v much_o the_o same_o there_o be_v no_o good_a to_o be_v do_v till_o the_o habitual_a cause_n be_v remove_v viz._n the_o take_v of_o opium_n which_o sudden_o to_o leave_v off_o be_v as_o be_v show_v very_o dangerous_a therefore_o in_o order_n to_o leave_v it_o off_o safe_o 1._o you_o must_v stop_v your_o hand_n and_o not_o increase_v the_o do_v that_o be_v take_v by_o which_o mean_v it_o will_v come_v gradual_o to_o have_v little_a or_o no_o effect_n 2._o when_o you_o find_v that_o it_o be_v come_v to_o that_o pass_n your_o work_n be_v half_o do_v then_o only_o lessen_v it_o 100th_o part_n every_o day_n till_o you_o come_v to_o take_v none_o at_o all_o 3._o if_o during_o this_o retrograde_a course_n you_o find_v any_o faintness_n drink_v a_o glass_n of_o good_a stomach-wine_n toties_fw-la quoties_fw-la as_o gentian_n or_o centary_a wine_n or_o the_o like_a make_v by_o infusion_n in_o claret_n or_o if_o you_o want_v such_o a_o glass_n of_o the_o claret_n itself_o which_o thing_n will_v excite_v the_o spirit_n and_o help_v digestion_n 4._o when_o you_o have_v quite_o end_v the_o take_v of_o opium_n continue_v to_o use_v such_o wine_n when_o you_o be_v faint_a and_o every_o morning_n take_v in_o a_o glass_n of_o
gentian_a wine_n two_o dram_fw-la of_o the_o chalybeate_a wine_n describe_v in_o the_o london_n dispensatory_a increase_v about_o a_o scruple_n every_o day_n till_o you_o come_v to_o half_a a_o ounce_n which_o take_v for_o two_o month_n at_o least_o afterward_o decrease_v as_o you_o increase_v till_o you_o come_v to_o one_o drachm_n and_o so_o give_v over_o but_o if_o you_o find_v oâ—osion_n you_o may_v continue_v that_o course_n long_o or_o as_o long_o as_o your_o physician_n think_v fit_a after_o all_o you_o may_v use_v a_o glass_n of_o claret_n when_o faint_a but_o be_v sure_a to_o be_v moderate_a and_o not_o run_v from_o one_o excess_n to_o another_o as_o for_o the_o acrimony_n of_o blood_n that_o be_v more_o during_o the_o take_v of_o opium_n and_o will_v soon_o after_o gradual_o wear_v off_o especial_o by_o the_o course_n direct_v if_o not_o camphire_n be_v the_o adequate_a remedy_n of_o which_o with_o equal_a part_n of_o white_a rosin_n and_o q._n s._n of_o mucilage_n of_o gum._n tragac._n you_o may_v make_v pill_n of_o â—_o grain_n weight_n take_v 4_o of_o they_o every_o night_n at_o bedtime_n in_o a_o rear_n yolk_n of_o a_o egg_n as_o long_o as_o it_o be_v necessary_a for_o camphire_n by_o its_o fine_a sulphur_n correct_v the_o volatile_a acrimony_n of_o cantharides_n opium_n etc._n etc._n and_o so_o allay_v titillation_n to_o venery_n etc._n etc._n as_o be_v observe_v iv_o the_o ill_a effect_n of_o a_o sudden_a leave_v off_o of_o opium_n as_o anxiety_n distress_n depression_n of_o spirit_n which_o as_o be_v say_v be_v very_o dangerous_a be_v remedy_v no_o other_o way_n but_o either_o 1._o by_o return_v to_o the_o use_v of_o opium_n which_o be_v a_o most_o certain_a cure_n and_o afterward_o if_o you_o please_v give_v over_o the_o use_n of_o it_o after_o the_o manner_n that_o i_o direct_v which_o you_o will_v find_v to_o be_v safe_a nor_o can_v i_o advise_v you_o to_o trust_v any_o other_o method_n of_o leave_v it_o off_o unless_o it_o be_v 2._o by_o substitute_v wine_n instead_o of_o opium_n which_o be_v not_o quite_o so_o safe_a or_o certain_a your_o best_a method_n of_o use_v it_o be_v to_o drink_v a_o good_a glass_n of_o it_o so_o often_o as_o to_o keep_v the_o comfort_n thereof_o at_o stomach_n continual_o that_o so_o it_o may_v answer_v the_o more_o permanent_a effect_n of_o opium_n and_o keep_v you_o from_o a_o faint_a condition_n but_o see_v also_o that_o this_o course_n be_v not_o convenient_a to_o be_v continue_v long_o you_o must_v gradual_o lessen_v the_o do_v of_o this_o as_o you_o be_v direct_v to_o do_v that_o of_o opium_n till_o you_o come_v to_o take_v none_o or_o at_o least_o a_o moderate_a and_o wholesome_a quantity_n note_v that_o if_o such_o as_o use_v to_o take_v opium_n be_v even_o almost_o expire_a for_o want_n of_o it_o you_o must_v to_o prevent_v imminent_a death_n give_v a_o liquid_a preparation_n thereof_o to_o the_o value_n of_o what_o the_o person_n be_v use_v to_o take_v in_o a_o cordial_a vehicle_n as_o spirit_n of_o wine_n brandy_n or_o the_o like_a because_o such_o hot_a spirituous_a vehicles_n do_v as_o have_v be_v show_v immediate_o give_v some_o comfort_n by_o actuate_a and_o warm_v our_o spirit_n till_o the_o opium_n come_v to_o operate_v which_o will_v not_o be_v long_o because_o it_o be_v in_o a_o liquid_a form_n if_o you_o find_v the_o person_n sink_v notwithstanding_o he_o may_v be_v keep_v up_o by_o repeat_v the_o brandy_n or_o cordial_n without_o any_o opium_n in_o it_o till_o the_o opiate_n operate_v which_o will_v certain_o by_o god_n help_n set_v he_o right_n in_o case_n it_o do_v but_o begin_v to_o operate_v before_o he_o be_v dead_a see_v the_o philos._n transact_v for_o june_n july_n august_n 1696._o note_v that_o it_o be_v a_o very_a false_a imagination_n that_o author_n have_v of_o the_o turk_n capacity_n by_o nature_n climate_n or_o the_o like_a to_o take_v more_o opium_n or_o in_o great_a quantity_n than_o we_o may_v but_o that_o they_o make_v more_o use_n of_o it_o and_o by_o that_o mean_n come_v to_o take_v 2_o or_o 3_o dram_fw-la a_o day_n for_o they_o begin_v with_o such_o small_a quantity_n as_o we_o common_o give_v till_o by_o a_o long_a custom_n of_o take_v it_o they_o come_v to_o take_v the_o say_a quantity_n which_o be_v but_o small_a in_o comparison_n of_o what_o several_a english_a people_n that_o have_v be_v use_v to_o it_o do_v or_o have_v take_v as_o i_o can_v name_v several_a to_o you_o if_o i_o have_v not_o reason_n to_o the_o contrary_a however_o i_o be_o at_o liberty_n to_o tell_v you_o the_o quantity_n though_o i_o must_v forbear_v name_v the_o person_n some_o have_v daily_o take_v 2_o 3_o 4_o 5_o 6_o dram_fw-la nay_o i_o have_v hear_v of_o some_o that_o have_v take_v a_o ounce_n a_o day_n and_o of_o one_o that_o take_v two_o ounce_n whereas_o the_o learned_a and_o curious_a dr._n edward_n smith_n can_v find_v none_o about_o smyrna_n who_o take_v above_o 3_o dram_fw-la a_o day_n all_o this_o be_v most_o agreeable_a to_o reason_n and_o the_o whole_a current_n of_o my_o discourse_n viz._n that_o it_o can_v be_v better_o bear_v in_o cold_a than_o hot_a wether_n and_o consequent_o in_o cold_a than_o hot_a climate_n by_o firm_a flesh_v person_n than_o such_o as_o have_v soft_a and_o flaccid_a flesh_n as_o the_o southern_a people_n have_v in_o comparison_n of_o the_o northern_a and_o such_o as_o inhabit_v cold_a country_n therefore_o you_o may_v be_v sure_a that_o such_o as_o inquire_v into_o the_o cause_n why_o the_o turk_n and_o other_o eastern_a people_n can_v take_v great_a quantity_n than_o we_o can_v seek_v for_o the_o reason_n of_o thing_n before_o they_o know_v the_o fact_n nay_o when_o the_o fact_n be_v quite_o contrary_a to_o what_o they_o build_v upon_o we_o may_v as_o well_o expect_v edify_v discourse_n from_o they_o that_o inquire_v why_o fire_n be_v cold_a water_n dry_a and_o the_o like_a as_o from_o such_o as_o suppose_v thing_n contrary_a to_o true_a and_o sensible_a experience_n chap._n xxix_o some_o general_a rule_n caution_n &c_n &c_n concern_v the_o use_n of_o opium_n though_o there_o be_v hardly_o any_o rule_n caution_n or_o thing_n worthy_a of_o observation_n concern_v the_o use_n of_o opium_n but_o what_o be_v imply_v or_o easy_o inferable_a from_o what_o have_v be_v say_v nor_o now_o that_o the_o true_a nature_n of_o opium_n be_v discover_v can_v there_o be_v such_o fear_n and_o jealoufy_v which_o multiply_v caution_n concern_v the_o administration_n thereof_o for_o every_o one_o may_v now_o easy_o see_v wherein_o its_o danger_n and_o benefit_n lie_v yet_o because_o a_o chapter_n of_o rule_n and_o caution_n may_v be_v expect_v as_o be_v usual_a and_o to_o have_v a_o single_a view_n of_o such_o as_o lie_v more_o scatter_v and_o not_o so_o ready_o find_v in_o the_o body_n of_o the_o book_n i_o will_v to_o introduce_v the_o use_n of_o opium_n with_o more_o clearness_n and_o perfect_a security_n give_v you_o a_o collection_n of_o general_a rule_n and_o caution_n concern_v its_o use_n whereof_o some_o be_v mention_v and_o most_o inferable_a from_o the_o premise_n i._o as_o to_o its_o substance_n 1._o it_o shall_v be_v always_o give_v free_v from_o its_o resinous_n part_n if_o you_o can_v get_v such_o a_o preparation_n 2._o it_o be_v also_o neat_a and_o convenient_a that_o it_o shall_v be_v free_v from_o all_o its_o earth_n and_o dress_n 3._o never_o give_v opium_n but_o either_o so_o prepare_v or_o with_o its_o rosin_n so_o subdue_v segregated_a or_o alter_v as_o i_o have_v show_v in_o the_o safe_a preparation_n thereof_o iâ—_n follow_v that_o 4._o crude_a opium_n and_o extract_v make_v in_o sulphureous_a spirit_n be_v utter_o to_o be_v reject_v 5._o never_o give_v it_o mix_v or_o join_v with_o resinous_a thing_n as_o have_v be_v intimate_v 6._o never_o mix_v or_o join_v it_o with_o other_o opiate_n 1._o because_o none_o of_o they_o be_v so_o good_a 2._o because_o they_o be_v not_o so_o well_o know_v 3._o because_o it_o make_v the_o do_v more_o uncertain_a 4._o because_o those_o other_o opiate_n be_v use_v unprepared_a 7._o pil._n e_o styrace_n because_o make_v of_o resinous_a opium_n join_v with_o resinous_a thing_n as_o styrax_fw-la calam_fw-la and_o olibanum_n be_v a_o insufferable_a preparation_n though_o commend_v and_o therefore_o have_v frequent_a ill_a effect_n to_o my_o knowledge_n 8._o pil._n â—_o cynoglossâ_fw-la be_v such_o another_o have_v two_o opiate_n in_o it_o beside_o opium_n extract_v out_o of_o spirit_n of_o wine_n which_o be_v far_o worse_a than_o crude_a opium_n though_o by_o the_o way_n of_o eminence_n call_v opium_n prepare_v in_o our_o dispensatory_a styrax_n calam_fw-la and_o olibanum_n which_o be_v resinous_a 9_o laudan_n lond._n be_v also_o a_o ill_a preparation_n as_o have_v the_o
spirit_n and_o not_o a_o over-relaxation_n or_o dilatation_n of_o the_o pore_n which_o must_v be_v well_o distinguish_v i._o the_o form_n must_v be_v liquid_a in_o all_o fever_n and_o be_v also_o most_o convenient_a general_o speak_v ii_o the_o do_v may_v be_v the_o moderate_a or_o middling_a except_o it_o be_v where_o the_o pain_n be_v great_a or_o where_o much_o of_o the_o opiate_n be_v lose_v as_o in_o vomit_v looseness_n etc._n etc._n for_o which_o see_v the_o general_n rule_v iii_o the_o vehicle_n shall_v be_v general_o speak_v cool_v compose_v and_o incrassate_v liquid_n as_o emulsion_n milk_n and_o water_n or_o the_o like_a but_o in_o settle_v the_o stomach_n use_v agreeable_a warm_a and_o comfortable_a cordial_n or_o wine_n burn_v with_o aromatics_n or_o the_o like_a iv_o the_o time_n be_v when_o it_o be_v convenient_a according_a to_o the_o general_n rule_v and_o your_o intention_n of_o its_o operation_n therefore_o where_o there_o be_v periodical_a paroxysm_n or_o exacerbation_n as_o in_o the_o smallpox_n and_o many_o disease_n in_o the_o afternoon_n or_o towards_o the_o evening_n give_v it_o the_o due_a time_n before_o that_o it_o may_v have_v its_o full_a effect_n by_o the_o time_n the_o paroxysm_n or_o exacerbation_n be_v expect_v to_o begin_v and_o be_v not_o so_o mad_a as_o to_o be_v regulate_v by_o night_n or_o day_n or_o bedtime_n etc._n etc._n as_o be_v usual_a which_o be_v no_o symptom_n sign_n or_o effect_n of_o the_o distemper_n but_o of_o the_o motion_n or_o position_n of_o the_o sun_n star_n &c_n &c_n which_o be_v not_o the_o subject_n of_o your_o cure_n nor_o can_v be_v the_o want_n of_o which_o most_o obvious_a and_o rational_a practice_n have_v sad_o disappoint_v inconsiderate_a physician_n and_o often_o hazard_v if_o not_o destroy_v the_o patient_n v._o the_o regimen_n be_v the_o same_o as_o that_o to_o cause_v sleep_n which_o you_o have_v in_o chap._n 35._o and_o shall_v be_v by_o all_o mean_v use_v in_o this_o case_n 1._o note_v that_o opiate_n be_v not_o to_o be_v use_v as_o have_v be_v intimate_v where_o the_o commotion_n flux_n etc._n etc._n be_v for_o apparent_a and_o speedy_a benefit_n of_o nature_n as_o in_o vomit_v upon_o repletion_n or_o to_o discharge_v the_o stomach_n of_o somewhat_o that_o offend_v it_o or_o a_o looseness_n to_o clear_v the_o intestine_n or_o the_o like_a 2._o note_v that_o when_o any_o evacuation_n be_v to_o be_v make_v by_o vomit_n or_o stool_n the_o best_a way_n in_o these_o case_n be_v to_o use_v large_a dilution_n of_o some_o contemperate_a liquid_a instead_o of_o vomitory_n and_o purger_n therefore_o use_v only_o lukewarm_a water_n or_o which_o be_v best_a boil_v with_o a_o little_a carduus_fw-la in_o it_o or_o carduus-posset_n or_o the_o like_a to_o cause_v vomit_v and_o more_o agreeable_a dilution_n for_o the_o intestine_n to_o wash_v off_o ill_a humour_n as_o a_o gallon_n of_o water_n with_o half_a a_o ounce_n of_o cream_n of_o tartar_n or_o rather_o the_o purge_a salt_n of_o the_o water_n dissolve_v in_o it_o or_o some_o part_n thereof_o use_v all_o cold_a or_o but_o very_o little_o warm_v give_v the_o opiate_n or_o panacea_fw-la immediate_o after_o the_o person_n have_v do_v vomit_v or_o purge_v in_o a_o small_a glass_n of_o wine_n or_o agreeable_a cordial_n to_o warm_v and_o comfort_v the_o stomach_n and_o intestine_n which_o because_o of_o the_o smallness_n of_o the_o quantity_n the_o moisture_n and_o coolness_n of_o the_o dilute_a liquid_n and_o the_o opiate_n can_v cause_v no_o inconvenience_n by_o its_o inconsiderable_a heat_n chap._n xxxiii_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o relax_v have_v show_v that_o opiate_n relax_v all_o the_o sensile_a part_n of_o the_o body_n and_o bow_n and_o why_o it_o follow_v that_o they_o be_v of_o excellent_a use_n 1._o to_o prevent_v and_o take_v away_o all_o contraction_n that_o happen_v from_o grievous_a passion_n or_o sensation_n or_o pain_n as_o convulsion_n sâ—iverings_n shake_v cramp_n tension_n palpitation_n and_o tremor_n of_o the_o heart_n from_o fear_n terror_n grief_n melancholy_n anxiety_n solicitude_n anger_n fretfulness_n concern_v surprise_v etc._n etc._n or_o from_o cold_a pain_n acid_n etc._n etc._n as_o contraction_n of_o the_o sphincter_n of_o the_o bladder_n from_o those_o cause_n by_o which_o the_o urine_n be_v often_o stop_v as_o also_o by_o the_o pain_n from_o the_o haemorrhoid_v inflammation_n small_a pox_n colick_n acrimony_n excoriation_n etc._n etc._n which_o often_o hinder_v the_o make_n of_o water_n as_o they_o also_o do_v sometime_o go_v to_o stool_n swallow_v etc._n etc._n shiver_a in_o ague-fits_a stupor_n from_o cold_a or_o pain_v which_o as_o be_v show_v proceed_v from_o a_o violent_a contraction_n in_o all_o which_o it_o will_v scarce_o ever_o fail_v of_o due_a effect_n by_o this_o mean_v you_o may_v as_o i_o have_v often_o do_v cure_v those_o disaster_n safe_o speedy_o and_o pleasant_o even_o to_o a_o wonder_n and_o amazement_n as_o if_o charm_v by_o a_o spell_n when_o other_o know_v not_o what_o hand_n to_o put_v to_o they_o and_o be_v quite_o baffle_v thereby_o by_o the_o same_o mean_n though_o little_a or_o not_o at_o all_o mind_a you_o may_v prevent_v great_a tumor_n upon_o pain_n as_o when_o by_o a_o thorn_n or_o any_o grievous_a pain_n the_o arm_n leg_n thigh_n etc._n etc._n begin_v to_o swell_v for_o the_o swell_a which_o often_o grow_v prodigious_o and_o seize_v the_o whole_a limb_n if_o not_o a_o great_a part_n of_o the_o body_n threaten_v and_o often_o cause_v mortification_n and_o death_n itself_o be_v cause_v by_o the_o pain_n contract_v and_o so_o gird_v the_o part_n that_o the_o blood_n lympha_fw-la &c._n &c._n can_v pass_v by_o which_o mean_v the_o humour_n be_v stagnate_v and_o crowd_v in_o by_o the_o force_n of_o the_o artery_n and_o damn_v up_o by_o the_o contraction_n most_o dreadful_a tumor_n happen_v whereas_o the_o pain_n be_v take_v away_o by_o the_o opiate_n and_o all_o the_o part_n relax_v they_o be_v and_o must_v be_v prevent_v by_o plain_a mechanism_n if_o use_v timely_a for_o pain_n can_v cause_v tumor_n by_o no_o other_o mean_n beside_o contraction_n which_o opium_n must_v prevent_v by_o take_v away_o the_o very_a pain_n itself_o 2._o to_o help_v the_o cure_n of_o all_o other_o contraction_n as_o tension_n rigidity_n of_o nerve_n membrane_n tendon_n ligament_n muscle_n etc._n etc._n 3._o to_o relax_v or_o make_v way_n for_o thing_n to_o pass_v as_o sweat_v 〈◊〉_d small_a pox_n measles_n pestilential_a or_o venomous_a esslâ—vias_n mâ—nses_n lochia_n and_o the_o like_a to_o pass_v through_o the_o skin_n or_o pore_n a_o child_n dead_z or_o alive_a afterbirth_n mole_n clod_v blood_n etc._n etc._n to_o pass_v through_o the_o neck_n of_o the_o womb_n when_o too_o narrow_a by_o nature_n or_o contract_v by_o pain_n cold_a terror_n etc._n etc._n a_o stone_n to_o pass_v the_o ureter_n or_o neck_n of_o the_o bladder_n by_o take_v away_o the_o pain_n that_o contract_v they_o and_o hinder_v the_o passage_n of_o the_o stone_n so_o that_o in_o the_o hand_n of_o a_o ingenious_a physician_n there_o be_v not_o a_o better_a nor_o as_o good_a a_o remedy_n to_o cause_v a_o stone_n of_o any_o passable_a bigness_n to_o come_v away_o for_o it_o pass_v through_o the_o relaxed_a or_o widen_v passage_n without_o pain_n to_o help_v which_o other_o relaxer_n as_o warmth_n 〈◊〉_d bathâ—_n fomentation_n clyster_n together_o with_o slippery_a and_o emollient_a thing_n inward_o take_v and_o at_o last_o a_o great_a stream_n of_o urine_n well_o contrive_v and_o time_v when_o the_o part_n be_v most_o relax_v supple_v and_o lubricate_v do_v much_o conduce_v i_o will_v have_v all_o who_o be_v trouble_v with_o the_o stone_n note_v this_o note_v also_o that_o to_o hold_v and_o dam_v up_o the_o urine_n a_o long_a time_n be_v of_o excellent_a use_n well_o manage_v when_o the_o stone_n be_v in_o the_o ureter_n because_o when_o the_o urine_n have_v fill_v up_o the_o bladder_n very_o tight_o that_o it_o will_v receive_v no_o more_o it_o must_v distend_v the_o ureter_n which_o be_v the_o cause_n that_o very_o many_o be_v ease_v either_o by_o the_o removal_n or_o discharge_v of_o the_o stone_n after_o a_o set_a time_n which_o give_v occasion_n to_o call_v they_o fit_v of_o the_o stone_n because_o they_o last_o for_o much_o about_o the_o same_o length_n of_o time_n however_o the_o large_a and_o sudden_a evacuation_n of_o urine_n must_v by_o leave_v the_o part_n loose_a etc._n etc._n conduce_v very_o much_o to_o the_o passage_n of_o the_o stone_n clod_n of_o blood_n phlegm_n matter_n etc._n etc._n that_o step_v the_o urine_n 4._o to_o relax_v or_o make_v way_n for_o thing_n to_o be_v put_v into_o the_o body_n when_o there_o be_v occasion_n as_o in_o reduction_n of_o hernias_fw-la or_o rupture_n of_o a_o fall_v fundament_n womb_n or_o