noxious_a rosin_n and_o all_o filth_n and_o dross_n of_o the_o opium_n 2._o it_o must_v be_v keep_v entire_a without_o weaken_v or_o any_o way_n alter_v it_o or_o add_v a_o new_a quality_n thereto_o therefore_o 1._o opium_n must_v not_o be_v torrefy_v according_a to_o the_o common_a practice_n 1._o because_o the_o fine_a and_o most_o volatile_a part_n which_o be_v the_o very_o best_a be_v thereby_o lose_v 2._o because_o the_o resinous_a and_o earthy_a part_n which_o be_v not_o spend_v that_o way_n grow_v more_o in_o proportion_n to_o the_o sal-volatile-oleosum_a so_o that_o torrefy_v can_v be_v allow_v unless_o preserve_v the_o bad_a and_o destroy_v the_o good_a be_v allowable_a the_o vain_a and_o ostentatious_a pretence_n of_o destroy_v i_o know_v not_o what_o narcotick_a sulphur_n which_o be_v a_o nickname_n give_v by_o ignorance_n to_o the_o best_a part_n of_o opium_n be_v most_o insufferable_a stuff_n 3._o because_o all_o empyreùm_fw-la which_o render_v it_o very_o nauseous_a can_v hardly_o be_v avoid_v in_o torresy_v it_o but_o suppose_v it_o be_v what_o need_n be_v there_o otherwise_o so_o to_o damnify_v it_o as_o be_v aforesaid_a obj._n it_o be_v find_v to_o be_v more_o innocent_a after_o such_o torrefaction_n ans._n i_o grant_v that_o it_o happen_v so_o sometime_o but_o it_o must_v be_v mere_o by_o accident_n either_o 1._o because_o it_o meet_v with_o a_o strong_a digestion_n at_o stomach_n or_o 2._o by_o the_o custom_n of_o powder_a it_o which_o be_v always_o direct_v and_o do_v after_o the_o torrefaction_n by_o which_o mean_v the_o resinous_a part_n be_v divide_v and_o sever_v become_v less_o liable_a to_o a_o coalescence_n at_o stomach_n and_o consequent_o less_o offensive_a and_o more_o subduable_a especial_o 3._o when_o it_o be_v mix_v as_o general_o it_o be_v with_o other_o thing_n that_o keep_v the_o part_n of_o the_o rosin_n from_o coalescence_n and_o leave_v they_o more_o conquerable_a by_o the_o digestion_n as_o the_o ancient_n find_v by_o experience_n who_o therefore_o do_v general_o if_o not_o always_o mix_v it_o in_o a_o small_a quantity_n with_o many_o other_o thing_n in_o great_a quantity_n in_o the_o form_n of_o electuary_n as_o in_o venice-treacle_n mithridate_n etc._n etc._n though_o nothing_o in_o they_o correct_v the_o opium_n otherwise_o than_o by_o divide_v and_o segregate_a its_o part_n this_o indeed_o be_v like_o that_o of_o divide_v &_o impera_fw-la or_o interline_v suspect_v soldier_n with_o trusty_a or_o friendly_a one_o to_o prevent_v a_o mischievous_a conspiracy_n but_o how_o much_o better_o be_v it_o to_o have_v no_o enemy_n to_o contest_v with_o by_o a_o due_a and_o complete_a separation_n of_o the_o rosin_n from_o the_o opium_n otherwise_o you_o must_v be_v oblige_v to_o good_a accident_n if_o ever_o torrefy_v opium_n become_v safe_a because_o all_o the_o noxious_a rosin_n be_v leave_v in_o it_o therefore_o if_o after_o torrefaction_n you_o will_v give_v it_o in_o a_o mass_n without_o powder_a it_o and_o mix_v it_o with_o other_o thing_n you_o will_v find_v its_o ill_a effect_n to_o be_v as_o bad_a if_o not_o worse_o than_o ever_o as_o you_o will_v also_o if_o you_o afterward_o extract_v it_o out_o of_o spirit_n of_o wine_n reduce_v it_o into_o the_o form_n of_o pill_n by_o which_o mean_v the_o sever_a part_n of_o the_o powdered_a rosin_n do_v again_o coalesce_v into_o a_o lumpish_a condition_n which_o render_v it_o worse_o than_o crude_a opium_n as_o wedelius_n myself_o and_o other_o do_v testify_v because_o the_o opium_n be_v somewhat_o weaken_v and_o all_o the_o rosin_n remain_v the_o do_v of_o the_o opium_n and_o consequent_o of_o its_o rosin_n must_v be_v increase_v as_o suppose_v 8_o grain_n of_o crude_a opium_n have_v 2_o of_o rosin_n 2_o of_o other_o dross_n 2_o of_o phlegm_n and_o 2_o of_o sal-volatile-oleosum_a and_o that_o 2_o grain_n of_o the_o crude_a opium_n contain_v half_o a_o grain_n of_o the_o sal-volotile-oleosum_a be_v the_o dose_n then_o if_o in_o torrefy_v it_o one_o grain_n of_o the_o sal-volatile-oleosum_a be_v lose_v and_o another_o of_o the_o phlegm_n there_o will_v remain_v only_o 6_o grain_n of_o the_o opium_n with_o the_o virtue_n of_o one_o grain_n of_o the_o sal-volatile-oleosum_a in_o it_o therefore_o 3_o grain_n of_o it_o must_v be_v now_o use_v to_o have_v half_o a_o grain_n of_o the_o sal-volatile-oleosum_a which_o 3_o grain_n will_v contain_v half_o the_o rosin_n of_o the_o whole_a mass_n that_o be_v one_o grain_n whereas_o there_o be_v but_o half_a a_o grain_n thereof_o in_o the_o 2_o grain_n of_o crude_a opium_n therefore_o torrefy_v opium_n be_v in_o itself_o much_o worse_a than_o crude_a opium_n and_o it_o be_v yet_o worse_o if_o after_o torrefication_n you_o make_v a_o extract_n of_o it_o in_o spirit_n of_o wine_n for_o then_o the_o dross_n and_o phlegm_n be_v separate_v from_o the_o 6_o grain_n nothing_o will_v remain_v in_o the_o extract_v but_o the_o resinous_a part_n with_o less_o of_o the_o virtue_n of_o the_o sal-volatile-oleosum_a which_o be_v not_o take_v up_o so_o greedy_o as_o the_o rosin_n be_v by_o the_o spirit_n of_o wine_n beside_o that_o some_o of_o this_o volatile_a part_n may_v be_v lose_v and_o that_o the_o rosin_n be_v now_o more_o compact_v as_o not_o have_v as_o much_o as_o the_o drossy_a earthy_a or_o watery_a part_n to_o sever_v and_o keep_v its_o noxious_a particle_n at_o a_o distance_n to_o render_v they_o as_o be_v show_v more_o subduable_a and_o digestible_a at_o stomach_n see_v what_o pain_n the_o inconsiderate_a world_n do_v take_v and_o exceed_o host_n of_o to_o render_v opium_n by_o torrefaction_n extraction_n in_o spirit_n of_o wine_n etc._n etc._n at_o least_o twice_o as_o nozious_a as_o crude_a opium_n without_o account_v how_o far_o the_o sal-volatile-oleosum_a that_o remain_v be_v impair_v by_o the_o fire_n and_o spirit_n of_o wine_n it_o be_v therefore_o no_o wonder_n that_o wedelius_n declare_v that_o he_o find_v more_o mischief_n by_o such_o extract_v out_o of_o spirit_n of_o wine_n than_o any_o other_o preparation_n of_o opium_n it_o be_v plain_a then_o ii_o that_o we_o must_v not_o extract_v it_o out_o of_o spirit_n of_o wine_n or_o any_o such_o sulphureous_a menstruum_fw-la 1._o because_o more_o apt_a to_o extract_v the_o rosin_n than_o the_o sal-volatile-oleosum_a 2._o because_o the_o rosin_n will_v be_v more_o compact_v 3._o because_o the_o spirit_n of_o wine_n may_v in_o some_o measure_n alter_v it_o iii_o we_o must_v not_o extract_v opium_n first_o out_o of_o water_n and_o afterward_o out_o of_o spirit_n of_o wine_n and_o then_o mix_v they_o together_o and_o evaporate_v they_o to_o a_o extract_n for_o this_o be_v as_o be_v say_v wise_o take_v care_n to_o add_v the_o poison_n to_o the_o panacea_fw-la or_o rosin_n extract_v by_o the_o spirit_n of_o wine_n to_o the_o sal-volatile-oleosum_a extract_v by_o the_o water_n beside_o the_o impair_v and_o loss_n make_v of_o the_o sal-volatile-oleosum_a by_o the_o spirit_n of_o wine_n and_o the_o evaporation_n how_o gentle_a soever_o it_o be_v here_o it_o will_v be_v seasonable_a to_o note_v that_o there_o be_v a_o general_a great_a fault_n commit_v by_o preparer_n of_o medicament_n especial_o such_o as_o pretend_v to_o most_o curiosity_n therein_o in_o endeavour_v right_a or_o wrong_n to_o have_v all_o the_o principle_n of_o the_o plant_n etc._n etc._n join_v together_o in_o their_o medicament_n however_o noxious_a or_o contrary_a to_o the_o purpose_n as_o you_o see_v in_o the_o instance_n just_o now_o mention_v whereas_o they_o have_v much_o better_o do_v as_o the_o great_a helmont_n say_v pharm_n &_o dispen_v modern_a 12._o saâ—guinem_fw-la a_o cruore_fw-la &_o parenâ—hymale_a plantarum_fw-la distinguere_fw-la &_o separare_fw-la discant_fw-la tyrones_n si_fw-la quicquam_fw-la laud_fw-la dignum_fw-la per_fw-la simplicia_fw-la egisse_fw-la meditentur_fw-la that_o be_v let_v beginner_n learn_v to_o distinguish_v and_o separate_v the_o true_a blood_n of_o plant_n from_o their_o cruor_fw-la or_o dead_a gore_n and_o parenchyma_n if_o they_o think_v to_o do_v any_o thing_n praiseworthy_a by_o simple_n you_o will_v find_v this_o to_o be_v very_o pat_o in_o the_o true_a preparation_n of_o the_o sal-volatile-oleosum_a who_o ruby-colour_n make_v it_o look_v like_a blood_n while_o the_o rosin_n earth_n and_o dross_n make_v the_o appearance_n of_o a_o dull_a and_o dead_a cruor_fw-la or_o gore_n if_o they_o take_v a_o tincture_n of_o opium_n in_o spirit_n of_o wine_n and_o use_v it_o so_o it_o will_v not_o be_v so_o bad_a for_o then_o the_o resinous_a particle_n be_v disseminated_a and_o not_o so_o liable_a to_o coalescence_n at_o stomach_n but_o so_o great_a be_v the_o stupidity_n that_o they_o take_v care_n by_o reduce_v it_o into_o the_o form_n of_o a_o extract_n to_o combine_v they_o and_o make_v they_o as_o noxious_a as_o be_v possible_a and_o then_o they_o think_v they_o worthy_a to_o be_v boast_v of_o as_o their_o nostrum_n
good_a humour_a of_o which_o he_o be_v seldom_o capable_a and_o utter_o incapable_a of_o all_o or_o most_o of_o the_o other_o brisk_a effect_n as_o euphory_n promptitude_n to_o venus_n exertion_n of_o courage_n etc._n etc._n it_o be_v either_o pass_v by_o as_o a_o ordinary_a thing_n of_o course_n and_o so_o not_o heed_v or_o else_o impute_v to_o refreshment_n by_o sleep_n ease_n from_o pain_n or_o some_o amendment_n as_o to_o the_o disease_n or_o indeed_o to_o any_o thing_n rather_o than_o dispiriting_n and_o stupify_a opium_n that_o be_v so_o far_o in_o all_o opinion_n from_o exciting_a the_o spirit_n that_o all_o affirm_v conclude_v and_o agree_v that_o it_o diminish_v or_o disable_v they_o the_o like_a be_v to_o be_v say_v of_o any_o of_o the_o lively_a effect_n in_o case_n they_o happen_v and_o be_v observe_v though_o i_o do_v not_o see_v how_o they_o can_v so_o at_o least_o as_o any_o slander_n by_o will_v refer_v it_o to_o opium_n beside_o that_o as_o to_o some_o of_o the_o brisk_a effect_n especial_o that_o of_o venery_n great_a dose_n be_v requisite_a to_o render_v it_o any_o thing_n remarkable_a than_o be_v use_v in_o these_o western_a part_n and_o that_o modesty_n will_v much_o hinder_v the_o discovery_n of_o this_o effect_n be_v it_o not_o therefore_o very_o manifest_a that_o i_o have_v great_a cause_n to_o suspect_v that_o both_o ancient_n and_o modern_a physician_n consider_v thing_n by_o half_n since_o they_o do_v not_o take_v the_o most_o genuine_a property_n into_o their_o consideration_n and_o that_o they_o lay_v their_o foundation_n upon_o the_o most_o contrary_a effect_n to_o they_o it_o follow_v then_o that_o the_o general_a supposition_n of_o all_o the_o learned_a can_v no_o more_o solve_v the_o true_a property_n of_o opium_n in_o any_o probability_n than_o give_v the_o reason_n why_o fire_n harden_v clay_n can_v explain_v why_o it_o soften_v wax_n the_o reason_n do_v i_o say_v i_o shall_v have_v say_v than_o give_v the_o wrong_a reason_n why_o it_o harden_v clay_n show_v how_o it_o soften_v wax_n for_o it_o will_v appear_v in_o the_o follow_a chapter_n that_o they_o give_v no_o right_a reason_n for_o any_o effect_n of_o opium_n even_o those_o they_o ever_o allow_v to_o be_v its_o effect_n nor_o lay_v any_o true_a foundation_n to_o explain_v the_o least_o mean_a and_o plain_a effect_n thereof_o forasmuch_o as_o all_o their_o supposition_n be_v so_o false_a that_o there_o never_o be_v any_o such_o thing_n as_o they_o lie_v down_o to_o explain_v the_o effect_n of_o opium_n viz._n 1._o no_o such_o thing_n as_o a_o cold_a quality_n in_o opium_n 2._o no_o such_o thing_n as_o fume_n etc._n etc._n fly_v from_o opium_n to_o the_o brain_n while_o it_o be_v at_o stomach_n 3._o no_o such_o thing_n as_o diminish_v or_o disable_n the_o animal_n spirit_n by_o opium_n any_o way_n whatsoever_o of_o which_o in_o their_o order_n in_o the_o follow_a chapter_n chap._n ix_o it_o be_v prove_v that_o opium_n have_v no_o cold_a quality_n to_o diminish_v or_o disable_v the_o spirit_n thereby_o have_v show_v just_a cause_n of_o my_o suspicion_n of_o that_o universal_a foundation_n of_o opium_n diminish_v or_o disable_n the_o spirit_n i_o will_v now_o proceed_v to_o a_o more_o strict_a examination_n thereof_o beginning_n with_o the_o opinion_n of_o the_o ancient_n who_o affirm_v that_o opium_n diminish_v or_o disable_v the_o spirit_n by_o a_o extreme_a cold_a quality_n i_o confess_v that_o much_o may_v be_v do_v towards_o the_o diminish_n or_o disable_n the_o spirit_n by_o opium_n if_o it_o have_v such_o a_o cold_a quality_n as_o the_o ancient_n attribute_v to_o it_o for_o than_o it_o must_v be_v such_o a_o coldness_n as_o the_o cold_a thing_n either_o actual_a or_o potential_a bear_v no_o proportion_n to_o for_o ice_n snow_n etc._n etc._n bear_v no_o proportion_n to_o it_o in_o cause_v the_o same_o effect_n by_o a_o cold_a quality_n it_o be_v the_o manner_n of_o the_o ancient_n implicit_o to_o believe_v and_o subscribe_v to_o what_o their_o great_a author_n and_o master_n in_o physic_n or_o philosophy_n teach_v they_o who_o they_o adore_v as_o infallible_a god_n as_o soon_o as_o their_o mortality_n prove_v the_o contrary_a which_o be_v as_o absurd_a as_o assert_v tha_z opium_n which_o be_v one_o of_o the_o hot_a thing_n that_o vegetable_n afford_v be_v extreme_a cold_a bless_a be_v god_n for_o our_o light_n in_o religion_n and_o liberty_n in_o philosophy_n therefore_o some_o such_o admire_a author_n or_o great_a master_n in_o physic_n have_v assert_v that_o opium_n act_v by_o a_o extreme_a cold_a quality_n all_o do_v implicit_o subscribe_v to_o it_o the_o devil_n who_o they_o worship_v can_v not_o though_o a_o deceiver_n from_o the_o beginning_n impose_v more_o upon_o their_o faith_n than_o in_o cause_v they_o for_o i_o can_v think_v but_o it_o be_v some_o such_o evil_a power_n to_o believe_v that_o opium_n be_v cold_a against_o all_o the_o evidence_n of_o sense_n and_o experience_n he_o may_v have_v as_o well_o tell_v they_o that_o hell_n fire_n have_v all_o the_o property_n of_o common_a culinary_a fire_n and_o yet_o nothing_o more_o refresh_v by_o its_o cold_a quality_n for_o as_o many_o of_o our_o sense_n as_o can_v take_v notice_n of_o heat_n and_o cold_a do_v plain_o inform_v we_o that_o it_o be_v very_o hot_a in_o itself_o and_o effect_n for_o 1._o it_o be_v taste_n be_v very_o bitter_a rank_a vehement_o hot_a burn_a and_o bite_v all_o which_o quality_n be_v infallible_a sign_n of_o great_a heat_n and_o the_o better_a the_o opium_n be_v the_o more_o intense_a be_v those_o quality_n nay_o it_o be_v observe_v that_o its_o very_a virtue_n be_v strict_o combine_v to_o or_o consist_v in_o those_o quality_n especial_o bitterness_n which_o if_o lose_v the_o virtue_n be_v go_v as_o be_v common_o observe_v and_o easy_o observable_a it_o be_v a_o wise_a fetch_v of_o amatus_fw-la lusitanus_n in_o defence_n of_o its_o cold_a quality_n to_o attribute_v all_o its_o bitterness_n to_o glaucium_fw-la that_o be_v mix_v therewith_o whereas_o glaucium_fw-la always_o give_v a_o yellow_a tincture_n to_o water_n and_o opium_n a_o red_a but_o the_o opium_n that_o give_v no_o yellow_a tincture_n be_v bitter_a also_o yea_o that_o be_v most_o bitter_a that_o give_v the_o red_a tincture_n how_o come_v theban_a opium_n and_o indeed_o all_o other_o opium_n to_o be_v bitter_a before_o any_o thing_n be_v mix_v with_o it_o how_o inadvertent_o absurd_a people_n will_v be_v to_o defend_v absurdity_n it_o be_v pretty_a to_o see_v how_o they_o will_v expose_v themselves_o to_o defend_v a_o false_a opinion_n 2._o it_o be_v smell_n which_o be_v very_a rank_n strong_a hot_a and_o such_o as_o thing_n high_o impregnate_v with_o volatile_a salt_n and_o sulphur_n the_o two_o hot_a principle_n in_o nature_n do_v afford_v it_o be_v from_o volatile_a salt_n that_o cantharides_n pismire_n spear-wort_n crowsfoot_n etc._n etc._n be_v so_o very_o hot_a as_o to_o blister_v or_o exulcerate_v and_o be_v not_o all_o hot_a spirit_n such_o upon_o the_o account_n of_o their_o sulphur_n as_o spirit_n of_o wine_n brandy_n etc._n etc._n 3._o the_o best_a and_o strong_a opium_n will_v also_o exulcerate_v as_o all_o author_n agree_v which_o only_a fire_n or_o such_o thing_n as_o have_v the_o particle_n of_o fire_n lodge_v in_o they_o as_o lixiviate_n etc._n etc._n or_o the_o hot_a thing_n in_o nature_n will_v do_v as_o cantharides_n spear-wort_n etc._n etc._n it_o be_v 4._o for_o the_o like_a reason_n a_o psilothrick_n or_o causer_n of_o hair_n to_o fall_v which_o only_a lime_n orpâ—ment_n and_o the_o hot_a thing_n do_v cause_n 5._o it_o be_v inflammable_a which_o only_o sulphurecus_fw-la thing_n be_v 6._o it_o cause_v a_o sense_n of_o a_o vehement_a heat_n at_o stomach_n though_o take_v but_o in_o the_o quantity_n of_o a_o drachm_n 7._o it_o cause_v dryness_n of_o the_o mouth_n and_o thirst_v though_o take_v but_o in_o the_o quantity_n of_o 3_o grain_n which_o nothing_o do_v but_o hot_a thing_n 8._o it_o discuss_n and_o all_o discusser_n be_v hot_a for_o it_o be_v by_o heat_n that_o they_o do_v discuss_v as_o spirit_n of_o wine_n cummin-seed_n volatile_a salt_n and_o all_o hot_a spirit_n 9_o it_o soon_o operate_v and_o in_o a_o small_a quantity_n which_o be_v a_o infallible_a proof_n of_o the_o activity_n of_o its_o part_n which_o argue_v heat_n not_o cold._a 10._o it_o cause_v a_o gay_a pleasant_a and_o merry_a humour_n which_o only_a wine_n and_o hot_a liquor_n etc._n etc._n do_v and_o one_o grain_n of_o opium_n will_v cause_v they_o as_o much_o as_o several_a glass_n of_o wine_n which_o argue_v that_o its_o heat_n be_v much_o great_a 11._o i_o will_v fain_o know_v how_o or_o see_v any_o instance_n of_o any_o cold_a thing_n raise_v the_o spirit_n cause_v courage_n magnanimity_n enable_v people_n to_o labour_n journey_n etc._n
which_o give_v the_o occasion_n as_o you_o may_v remember_v to_o the_o hypothesis_n of_o its_o operate_n by_o fume_n rise_v out_o of_o the_o stomach_n because_o they_o can_v not_o think_v of_o any_o other_o mean_v by_o which_o it_o may_v affect_v the_o head_n brain_n animal_n spirit_n nerve_n etc._n etc._n while_o it_o be_v at_o stomach_n but_o by_o the_o way_n of_o fume_n or_o vapour_n it_o be_v therefore_o past_a all_o doubt_n that_o opium_n produce_v its_o common_a effect_n while_o it_o be_v at_o stomach_n and_o before_o it_o arrive_v at_o the_o blood_n and_o therefore_o do_v not_o operate_v as_o a_o alterative_a thereof_o second_o because_o a_o grain_n of_o opium_n which_o operate_v very_o remarkable_o bear_v as_o etmuller_n well_o observe_v so_o small_a a_o proportion_n to_o the_o blood_n that_o it_o can_v produce_v such_o great_a and_o notable_a effect_n as_o a_o alterative_a thereof_o for_o a_o grain_n of_o opium_n to_o 20_o pound_n of_o blood_n which_o a_o ordinary_a man_n have_v in_o his_o body_n be_v but_o as_o 1_o to_o 115200_o or_o if_o 16_o oucne_n be_v allow_v to_o the_o pound_n as_o 1_o to_o 153600._o but_o it_o be_v no_o wonder_n if_o a_o grain_n shall_v affect_v the_o membrane_n at_o stomach_n since_o the_o 1000_o part_n of_o a_o grain_n of_o the_o vomitory_n particle_n of_o crocus_n metallorum_fw-la or_o regulus_n of_o antimony_n do_v affect_v it_o so_o eminent_o as_o many_o other_o thing_n will_v in_o a_o very_a small_a quantity_n whereas_o the_o alter_n of_o the_o blood_n to_o any_o observable_a degree_n require_v the_o use_n of_o alterative_n in_o great_a quantity_n for_o several_a week_n which_o confirm_v the_o former_a conclusion_n that_o opium_n do_v not_o operate_v as_o a_o alterative_a as_o to_o its_o common_a and_o usual_a effect_n ii_o opium_n do_v not_o operate_v by_o grievous_a sensation_n or_o irritation_n as_o vomit_n purger_n errhine_n salivator_n or_o apophlegmatizer_n etc._n etc._n do_v first_o because_o it_o manifest_o cause_v a_o very_a agreeable_a pleasant_a and_o even_o charm_a sensation_n second_o because_o it_o take_v away_o grievous_a sensation_n or_o pain_n thereby_o stop_v vomit_v purge_v and_o all_o other-effect_n of_o grievous_a sensation_n by_o acrimony_n etc._n etc._n as_o for_o the_o vomit_v that_o opium_n sometime_o cause_n it_o be_v only_o as_o shall_v be_v show_v by_o its_o resinous_n part_n stick_v to_o the_o coat_n of_o the_o stomach_n which_o be_v separate_v from_o it_o opium_n have_v no_o such_o effect_n though_o all_o its_o good_a effect_n remain_v so_o its_o purge_v which_o happen_v most_o rare_o and_o only_o when_o a_o great_a quantity_n be_v give_v to_o man_n of_o strong_a digestion_n it_o be_v only_o from_o its_o rosin_n digest_v and_o resolve_v in_o strong_a stomach_n hence_o it_o be_v that_o dog_n and_o such_o as_o have_v canine_a appetite_n do_v general_o purge_v after_o a_o great_a quantity_n of_o crude_a or_o rosinous_n opium_n whereas_o such_o as_o be_v not_o rosinous_n cause_v no_o such_o effect_n but_o of_o these_o matter_n more_o to_o your_o satisfaction_n hereafter_o three_o because_o it_o cause_v all_o effect_n that_o be_v quite_o contrary_a to_o those_o of_o grievous_a sensation_n it_o cause_v a_o ovation_n of_o the_o sensitive_a soul_n and_o spirit_n pain_n or_o grievous_a sensation_n a_o depression_n of_o spirit_n it_o cause_v euphory_n and_o pain_n weariness_n for_o what_o tire_v more_o than_o pain_n or_o labour_v in_o pain_n it_o cause_v good_a humour_n pain_n peevishness_n fretfulness_n and_o ill_a humour_n opium_n cause_v relaxation_n of_o all_o part_n pain_n contraction_n that_o cause_v free_a perspiration_n this_o check_v it_o that_o cause_v sleep_n this_o hinder_v it_o that_o cause_v contentation_n acquiescence_n this_o discontent_n and_o uneasiness_n that_o compose_v this_o discompose_v the_o spirit_n blood_n etc._n etc._n that_o cause_v flux_n by_o irritation_n etc._n etc._n this_o moderate_n or_o stop_v they_o that_o open_v the_o pore_n pain_n constr_v they_o opium_n prevent_v the_o shake_v fit_n in_o ague_n pain_n bring_v they_o on_o that_o cause_v a_o large_a and_o slow_a pulse_n this_o a_o quick_a hard_a and_o narrow_a pulse_n that_o cause_v a_o efflorescence_n of_o the_o skin_n this_o paleness_n that_o pleasant_a this_o unpleasant_a dream_n that_o still_v hiccough_n this_o cause_n they_o that_o take_v off_o contraction_n convulsion_n etc._n etc._n this_o cause_v they_o to_o be_v short_a opium_n cause_v all_o the_o effect_n of_o pleasant_a sensation_n and_o take_v off_o all_o the_o effect_n of_o grievous_a sensation_n what_o can_v be_v a_o more_o evident_a proof_n of_o its_o act_n by_o cause_v a_o pleasant_a sensation_n it_o be_v endless_a to_o mention_v all_o the_o proof_n that_o may_v be_v make_v to_o the_o same_o purpose_n from_o pleaser_n and_o displeaser_n of_o sensation_n therefore_o we_o fair_o conclude_v that_o opium_n do_v not_o operate_v by_o cause_v a_o grievovi_fw-la sensation_n and_o there_o be_v no_o other_o way_n leave_v by_o which_o it_o may_v operate_v it_o must_v operate_v by_o cause_v a_o pleasant_a sensation_n which_o be_v the_o true_a and_o plain_a reason_n why_o as_o have_v be_v show_v it_o take_v off_o pain_n and_o cause_v all_o effect_n quite_o contrary_a to_o that_o of_o grievous_a sensation_n irritation_n by_o acrimony_n etc._n etc._n which_o be_v most_o eminent_a upon_o the_o most_o sensible_a part_n as_o the_o stomach_n intestine_n venereal_a membrane_n skin_n etc._n etc._n as_o you_o may_v observe_v where_o the_o effect_n of_o opium_n be_v enumerate_v now_o gentle_a reader_n consider_v that_o contrary_n be_v the_o true_a cure_n of_o contrary_n what_o can_v then_o cure_v pain_n and_o all_o its_o effect_n better_a than_o pleasure_n it_o be_v very_o strange_a then_o that_o million_o for_o many_o age_n find_v opium_n cure_v or_o take_v off_o pain_n and_o all_o its_o effect_n above_o all_o thing_n shall_v not_o attribute_v its_o so_o do_v to_o its_o cause_v a_o pleasant_a sensation_n which_o be_v the_o direct_a contrary_n to_o pain_n especial_o since_o every_o man_n that_o take_v opium_n feel_v a_o actual_a pleasure_n upon_o take_v thereof_o pleasant_a dream_n a_o pleasant_a humour_n etc._n etc._n it_o may_v be_v say_v what_o if_o it_o be_v grant_v that_o opium_n operate_v by_o a_o please_a sensation_n which_o i_o will_v thank_v none_o for_o that_o have_v feel_v at_o stomach_n or_o reason_n at_o brain_n how_o be_v it_o possible_a that_o such_o pleasant_a sensation_n shall_v cause_v and_o explicate_v all_o the_o various_a strange_a wonderful_a mysterious_a and_o very_o often_o seem_o contradictory_n phenomena_n and_o effect_n of_o opium_n answer_n as_o easy_o as_o ever_o i_o explain_v any_o thing_n in_o nature_n especial_o if_o my_o tract_n of_o animal_n mechanism_n be_v publish_v but_o it_o be_v my_o misfortune_n that_o it_o be_v not_o however_o it_o shall_v not_o be_v the_o reader_n though_o it_o will_v put_v i_o to_o a_o great_a trouble_n to_o evade_v which_o be_v none_o of_o my_o intention_n by_o those_o word_n but_o rather_o to_o bespeak_v the_o reader_n be_v patience_n while_n i_o be_o premise_v some_o necessary_a praecognita_fw-la requisite_a to_o be_v know_v before_o i_o enter_v upon_o the_o explication_n of_o the_o wonderful_a and_o seem_o inexplicable_a effect_n of_o opium_n i_o therefore_o desire_v the_o reader_n be_v leave_v to_o premise_v some_o thing_n of_o the_o nature_n of_o sensation_n and_o sensitive_a pleasure_n in_o order_n to_o his_o more_o clear_a and_o ready_a understanding_n my_o explication_n of_o this_o mysterious_a and_o momentous_a matter_n look_v upon_o as_o so_o dark_a and_o abstruse_a a_o business_n to_o this_o day_n that_o some_o have_v not_o only_o yield_v it_o up_o as_o a_o thing_n hide_v from_o mankind_n but_o have_v earnest_o and_o serious_o argue_v that_o it_o act_v absolute_o by_o a_o occult_a quality_n reserve_v in_o a_o special_a manner_n as_o be_v the_o nature_n of_o spirit_n from_o our_o knowledge_n that_o it_o have_v be_v so_o hitherto_o i_o think_v none_o can_v deny_v as_o the_o circulation_n of_o the_o blood_n be_v for_o thousand_o of_o year_n though_o the_o very_a motion_n be_v see_v by_o million_o so_o as_o the_o cause_n of_o the_o operation_n of_o opium_n have_v be_v feel_v by_o a_o far_o great_a number_n it_o therefore_o will_v if_o i_o fail_v not_o in_o explain_v it_o appear_v so_o clear_a that_o it_o will_v be_v much_o wonder_v at_o like_o that_o of_o the_o circulation_n of_o the_o blood_n why_o so_o obvious_a a_o thing_n be_v not_o find_v by_o every_o one_o that_o use_v opium_n but_o whatever_o opium_n be_v god_n method_n be_v unsearchable_a and_o often_o his_o wise_a providence_n bestow_v good_a gift_n upon_o the_o unworthy_a that_o his_o free_a goodness_n may_v appear_v to_o who_o be_v all_o glory_n praise_n and_o thanksgiving_n for_o ever_o and_o ever_o amen_n note_v that_o while_o i_o be_o upon_o the_o
truth_n be_v that_o god_n and_o nature_n have_v give_v we_o our_o sense_n for_o that_o end_n and_o present_a refection_n in_o case_n of_o faintness_n depression_n of_o spirit_n and_o what_o more_o proper_a to_o convey_v comfort_n to_o we_o than_o what_o be_v sensible_a of_o it_o 2._o it_o be_v another_o thing_n to_o add_v by_o way_n of_o nutrition_n to_o our_o spirit_n which_o be_v insensible_a thing_n and_o therefore_o never_o proper_o comfort_v any_o more_o than_o a_o plant_n that_o be_v nourish_v as_o well_o as_o they_o but_o the_o sensitive_a soul_n be_v please_v must_v needs_o conceive_v satisfaction_n comfort_n joy_n etc._n etc._n how_o he_o can_v be_v please_v when_o sensible_a of_o nothing_o i_o know_v not_o nor_o how_o he_o can_v be_v comfort_v without_o be_v first_o please_v nor_o how_o please_v but_o by_o sensation_n 3._o the_o essence_n of_o animal_n comfort_n do_v not_o consist_v in_o have_v many_o spirit_n for_o one_o in_o most_o grievous_a pain_n and_o misery_n by_o which_o he_o be_v much_o discomfort_a cast_v down_o depress_v in_o spirit_n etc._n etc._n may_v have_v great_a plenty_n of_o spirit_n and_o one_o that_o have_v not_o half_a as_o many_o high_o comfort_v by_o please_a object_n of_o sense_n good_a news_n etc._n etc._n 4._o if_o we_o stay_v for_o comfort_n by_o a_o meal_n of_o meat_n etc._n etc._n till_o it_o add_v to_o our_o spirit_n we_o may_v stay_v long_o enough_o nay_o if_o we_o stay_v for_o comfort_n till_o we_o find_v it_o by_o that_o addition_n we_o shall_v never_o find_v it_o for_o we_o can_v in_o that_o case_n find_v what_o we_o do_v not_o feel_v we_o possible_o after_o two_o or_o three_o day_n eat_v and_o drink_v may_v find_v ourselves_o strong_a but_o after_o all_o suppose_v we_o in_o very_o great_a misery_n at_o the_o same_o time_n where_o be_v the_o comfort_n of_o it_o when_o the_o spirit_n be_v otherwise_o depress_v by_o pain_n ill_a news_n etc._n etc._n 5._o hunger_n be_v a_o grievous_a sensation_n at_o stomach_n which_o be_v cure_v and_o we_o comfort_v by_o cause_v a_o pleasant_a sensation_n by_o meat_n wine_n etc._n etc._n instead_o thereof_o and_o not_o by_o add_v spirit_n which_o be_v a_o great_a mistake_n it_o be_v true_a indeed_o that_o we_o be_v comfort_v but_o it_o be_v most_o manifest_o by_o please_v the_o exquisite_a sensation_n at_o stomach_n which_o god_n have_v place_v there_o for_o that_o end_n hence_o it_o be_v that_o all_o cordial_n must_v be_v please_v to_o the_o stomach_n or_o else_o they_o be_v no_o cordial_n and_o that_o wine_n and_o all_o such_o thing_n as_o please_v the_o stomach_n be_v apt_a to_o take_v away_o much_o of_o the_o sharpness_n of_o hunger_n for_o a_o time_n at_o least_o 6._o how_o shall_v wine_n which_o have_v a_o great_a acidity_n in_o it_o and_o so_o very_o good_a for_o digestion_n cure_v a_o canine_a appetite_n which_o be_v a_o grievous_a sensation_n but_o by_o cause_v a_o pleasant_a one_o in_o its_o room_n by_o which_o mean_v the_o grievous_a sensation_n be_v take_v off_o for_o pleasure_n and_o grievance_n or_o displeasure_n which_o be_v contrary_n can_v be_v in_o the_o same_o subject_a at_o one_o time_n thus_o it_o be_v that_o opium_n take_v off_o hunger_n canine_a appetite_n etc._n etc._n but_o of_o this_o hereafter_o 7._o how_o shall_v a_o quart_n of_o wine_n drink_v in_o a_o minute_n or_o two_o have_v all_o the_o comfortable_a effect_n of_o wine_n in_o a_o quarter_n of_o a_o hour_n while_o it_o be_v at_o stomach_n if_o it_o be_v to_o stay_v for_o this_o comfort_n till_o it_o add_v spirit_n to_o we_o since_o the_o matter_n of_o effluvia_fw-la or_o fume_n pass_v into_o the_o rloud_o be_v disprove_v 8._o why_o shall_v our_o comfort_n be_v so_o great_a while_o it_o be_v at_o stomach_n and_o none_o by_o that_o time_n it_o be_v get_v into_o the_o blood_n but_o that_o the_o stomach_n be_v very_o sensile_a the_o spirit_n of_o the_o wine_n do_v high_o please_v by_o their_o agreeableness_n thereunto_o it_o matter_n not_o whether_o it_o have_v spirit_n or_o no_o so_o it_o cause_v a_o please_a sensation_n for_o a_o draught_n of_o water_n in_o a_o high_a fever_n and_o when_o we_o be_v very_o faint_a with_o thirst_n very_o much_o comfort_v we_o without_o any_o spirit_n as_o do_v a_o venison-pasty_n a_o hungry_a person_n by_o agreeable_a sensation_n take_v off_o the_o grievous_a sensation_n call_v hunger_n and_o all_o its_o consequent_a faintness_n etc._n etc._n before_o it_o can_v add_v any_o spirit_n by_o nutrition_n 9_o what_o need_v we_o seek_v any_o far_a do_v not_o we_o find_v a_o please_a sensation_n at_o stomach_n when_o we_o be_v comfort_v with_o any_o thing_n and_o the_o comfort_n to_o bear_v a_o proportion_n to_o the_o pleasure_n 10._o be_v not_o we_o prompt_v blithe_a gay_a and_o brave_a while_o the_o wine_n be_v at_o stomach_n and_o very_o often_o fit_a for_o nothing_o dull_a heavy_a mopish_a etc._n etc._n by_o that_o time_n it_o be_v get_v into_o the_o blood_n therefore_o we_o may_v safe_o conclude_v that_o the_o spirit_n of_o the_o wine_n do_v comfort_v we_o by_o cause_v a_o please_a sensation_n and_o not_o by_o add_v its_o spirit_n to_o we_o according_a to_o the_o settle_a sentiment_n of_o the_o world_n that_o be_v not_o yet_o arrive_v to_o the_o learning_n or_o knowledge_n why_o the_o most_o common_a cordial_n comfort_v they_o what_o spirit_n have_v a_o grain_n of_o opium_n while_o at_o stomach_n to_o add_v to_o we_o or_o can_v it_o add_v if_o it_o have_v they_o yet_o no_o wine_n comfort_v we_o as_o much_o as_o opium_n because_o it_o please_v we_o so_o much_o as_o be_v and_o will_v be_v yet_o much_o more_o full_o show_v note_v that_o beside_o what_o be_v say_v of_o the_o grievousness_n of_o the_o three_o contraction_n to_o tiâ—e_v the_o animal_n or_o sensitive_a soul_n he_o be_v much_o depress_v and_o cast_v down_o upon_o the_o perception_n of_o grievance_n as_o hunger_n pain_n etc._n etc._n because_o they_o 1._o affect_v he_o with_o grief_n and_o displeasure_n and_o consequent_o with_o discomfort_n anxiety_n etc._n etc._n because_o of_o the_o very_a dolour_n 2._o with_o care_n and_o solicitude_n how_o to_o be_v rid_v of_o it_o 3._o with_o the_o toil_n of_o defensive_a contraction_n to_o endeavour_v it_o all_o which_o cause_v melancholy_a depression_n of_o spirit_n pusillanimity_n perturbation_n fret_n discomposure_n dissatisfaction_n anxiety_n solicitude_n peevishness_n discomposure_n discomfort_n listlesness_n etc._n etc._n as_o you_o see_v in_o such_o as_o be_v hungry_a or_o in_o pain_n to_o which_o if_o you_o add_v the_o fatigue_n and_o effect_n of_o the_o defensive_a contraction_n and_o the_o intentive_a as_o far_o as_o it_o be_v exercise_v for_o self-preservation_n in_o this_o case_n you_o may_v observe_v what_o have_v be_v say_v easy_o solve_v all_o the_o phenomena_n of_o grievous_a sensation_n and_o as_o easy_o conclude_v what_o must_v be_v the_o phenomena_n and_o effect_n of_o pleasant_a sensation_n by_o the_o rule_n of_o contrary_n viz._n satisfaction_n good_a humour_n ease_n comfort_n ovation_n of_o spirit_n relaxation_n etc._n etc._n of_o which_o we_o be_v go_v to_o speak_v chap._n fourteen_o of_o the_o nature_n of_o sensitive_a pleasure_n and_o its_o effect_n upon_o the_o animal_n as_o far_o as_o it_o concern_v our_o present_a purpose_n sensitive_a pleasure_n be_v a_o complacency_n of_o the_o sensitive_a soul_n result_v from_o the_o agreeableness_n of_o the_o object_n to_o the_o organ_n of_o sensation_n thus_o be_v we_o please_v with_o what_o be_v agreeable_a to_o the_o eye_n ear_n tongue_n stomach_n etc._n etc._n and_o what_o be_v agreeable_a to_o those_o organ_n be_v agreeable_a to_o the_o animal_n in_o general_a 1._o because_o god_n have_v make_v and_o appoint_v they_o especial_o the_o sensile_a membrane_n at_o stomach_n to_o be_v as_o it_o be_v the_o touchstone_n of_o what_o be_v agreeable_a to_o the_o animal_n 2._o because_o the_o membrane_n or_o organ_n be_v of_o the_o same_o active_a principle_n with_o the_o animal_n body_n in_o general_a otherwise_o they_o will_v not_o be_v fit_a taster_n trier_n or_o touchstone_n of_o what_o be_v good_a or_o bad_a for_o the_o body_n in_o general_n now_o the_o active_a principle_n of_o the_o membrane_n or_o organ_n be_v volatile_a salt_n and_o oily_a part_n or_o a_o shall_v volatile_a oleosum_fw-la which_o be_v predominant_a in_o they_o and_o all_o the_o part_n of_o the_o body_n therefore_o such_o thing_n as_o have_v a_o volatile_a salt_n join_v with_o some_o oily_a part_n must_v be_v in_o a_o special_a manner_n agreeable_a and_o please_a to_o the_o membrane_n for_o simile_n fimili_fw-la gaudeat_fw-la hence_o it_o be_v that_o what_o abound_v in_o volatile_a salt_n as_o snail_n earthworm_n and_o thing_n of_o that_o kind_n be_v such_o fine_a anodynes_n and_o so_o please_v to_o the_o membrane_n etc._n etc._n that_o the_o seed_n of_o animal_n
the_o cause_n of_o those_o ill_a effect_n in_o that_o they_o happen_v at_o stomach_n or_o from_o it_o by_o consent_n since_o opium_n have_v nothing_o in_o it_o that_o can_v offend_v the_o stomach_n but_o the_o rosin_n of_o which_o it_o be_v show_v in_o chap._n 14._o how_o very_o offensive_a it_o be_v to_o the_o stomach_n by_o its_o indigestibleness_n and_o stick_v to_o it_o but_o even_o intolerable_a if_o also_o arm_v with_o pungent_a particle_n such_o as_o volatile_a salt_n have_v with_o which_o opium_n abound_v 5._o it_o have_v be_v never_o observe_v that_o any_o preparation_n of_o opium_n that_o be_v separate_v from_o the_o râ—sinous_n part_n do_v ever_o cause_v any_o such_o ill_a effect_n but_o 6._o it_o have_v be_v often_o observe_v that_o if_o crude_a opium_n or_o a_o resinous_n preparation_n thereof_o be_v give_v alone_o in_o the_o form_n of_o pill_n or_o any_o solid_a form_n that_o it_o be_v very_o apt_a to_o cause_v those_o effect_n wedeâ—_n that_o he_o never_o observe_v those_o mischief_n but_o after_o preparation_n thereof_o in_o the_o form_n of_o pill_n and_o it_o follow_v from_o what_o he_o have_v say_v before_o that_o it_o be_v either_o crude_a opium_n or_o that_o horrid_a extract_n out_o of_o spirit_n of_o wine_n both_o which_o be_v resinous_n note_v that_o since_o the_o very_a form_n that_o it_o be_v give_v in_o do_v so_o much_o alter_v the_o case_n it_o follow_v that_o it_o be_v not_o poisonous_a in_o itself_o as_o such_o 7._o it_o be_v observe_v that_o crude_a opium_n extract_v in_o spirit_n of_o wine_n and_o such_o resinous_n preparation_n stay_v very_o long_o at_o stomach_n viz._n 4_o 5_o 6_o 7_o 8_o 9_o 10_o 11_o 12_o nay_o sometime_o 18_o or_o 20_o hour_n as_o charas_fw-la himself_z intimate_v in_o reference_n to_o a_o gentleman_n that_o take_v half_o a_o drachm_n of_o his_o extract_v 2_o or_o 3_o time_n a_o week_n that_o he_o vomit_v if_o he_o take_v a_o clyster_n before_o 20_o hour_n be_v expire_v after_o the_o take_n of_o it_o that_o certain_o argue_v that_o it_o or_o a_o great_a part_n thereof_o be_v still_o at_o stomach_n which_o stay_n be_v a_o most_o grievous_a thing_n to_o the_o stomach_n when_o it_o be_v beyond_o the_o usual_a time_n that_o thing_n be_v digest_v in_o it_o now_o such_o a_o stay_n can_v be_v attribute_v to_o nothing_o but_o the_o rosin_n stick_v to_o the_o coat_n of_o the_o stomach_n for_o that_o preparation_n of_o charas_fw-la have_v nothing_o in_o it_o but_o what_o be_v dissolve_v in_o water_n which_o be_v therefore_o always_o dissolvable_a at_o stomach_n and_o the_o rosin_n extract_v out_o of_o the_o spirit_n of_o wine_n therefore_o it_o be_v indissolvable_a and_o viscid_a rosin_n that_o cause_v so_o long_a a_o stay_n though_o that_o gentleman_n do_v by_o strength_n of_o digestion_n conquer_v it_o at_o last_o and_o that_o without_o vomit_v unless_o he_o as_o be_v say_v take_v a_o clyster_n within_o the_o 20_o hour_n it_o be_v long_a stay_n at_o stomach_n be_v manifest_a also_o in_o that_o after_o 20_o hour_n it_o purge_v he_o and_o not_o before_o which_o purge_v as_o shall_v be_v show_v hereafter_o and_o have_v be_v in_o some_o measure_n hint_v happen_v by_o the_o dissolution_n of_o the_o rosin_n by_o a_o strong_a digestion_n and_o therefore_o it_o happen_v only_o when_o resinous_n preparation_n be_v give_v in_o good_a quantity_n to_o man_n that_o have_v such_o a_o digestion_n or_o a_o canine_a appetite_n as_o a_o experience_a person_n in_o the_o matter_n of_o opium_n inform_v i_o and_o i_o since_o observe_v to_o be_v very_o true_a 8._o it_o must_v be_v somewhat_o in_o opium_n that_o be_v indigestible_a and_o stick_v to_o the_o stomach_n or_o else_o it_o can_v not_o cause_v vomit_v so_o long_o as_o it_o do_v that_o be_v 12_o 14_o 16_o or_o more_o hour_n whereas_o other_o vomit_n do_v general_o operate_v but_o for_o 2_o or_o 3_o hour_n at_o sarth_a and_o opium_n have_v nothing_o in_o it_o indigestible_a and_o stick_v but_o its_o rosin_n 9_o it_o be_v to_o be_v note_v that_o when_o opium_n be_v prepare_v join_v or_o give_v with_o such_o thing_n as_o destroy_v or_o prevent_v the_o stick_n of_o its_o rosin_n to_o the_o stomach_n and_o help_v its_o dissolution_n digestion_n or_o drip_v out_o of_o the_o stomach_n it_o cause_v no_o such_o ill_a effect_n though_o crude_a opium_n or_o a_o resinous_n preparation_n be_v give_v thus_o if_o you_o prepare_v it_o by_o lixivial_n which_o alter_v the_o nature_n of_o the_o rosin_n by_o as_o it_o be_v soapify_a it_o and_o thereby_o take_v away_o its_o stick_a quality_n and_o render_v it_o as_o soap_n be_v dissolvable_a slippery_a and_o passable_a at_o stomach_n it_o cause_v no_o such_o disturbance_n hence_o it_o be_v that_o lixivial_n be_v find_v to_o be_v such_o true_a corrector_n of_o opium_n though_o the_o reason_n have_v not_o be_v consider_v as_o will_v appear_v hereafter_o and_o that_o the_o sapo_n tartarus_n make_v matthew_n or_o starkey_n pill_n and_o the_o pilulae_fw-la pacificâ—_fw-la so_o safe_a and_o free_a from_o ill_a effect_n as_o also_o salt_n of_o tartar_n do_v libavius'â—_n and_o langelott_n famous_a preparation_n of_o which_o expect_v more_o when_o i_o come_v to_o speak_v of_o the_o preparation_n of_o opium_n in_o chap._n 26._o so_o 10._o if_o you_o subdue_v opium_n as_o you_o do_v rosin_n and_o turpontine_n with_o the_o yolk_n of_o a_o egg_n before_o you_o give_v it_o it_o become_v safe_a because_o you_o by_o that_o mean_n dissolve_v its_o rosin_n and_o prevent_v its_o adhere_n to_o the_o coat_n of_o the_o stomach_n and_o render_v it_o digestible_a and_o passable_a which_o be_v a_o most_o certain_a sign_n that_o its_o rosin_n cause_v those_o ill_a effect_n 11._o it_o be_v for_o the_o same_o reason_n that_o opium_n fine_o powder_v and_o mix_v with_o other_o thing_n that_o keep_v its_o resinous_n part_n from_o a_o coalescence_n as_o in_o venice_n treacle_n etc._n etc._n that_o it_o be_v not_o so_o apt_a to_o cause_v those_o evil_a effect_n this_o i_o doubt_v not_o make_v the_o ancient_n who_o have_v no_o better_a way_n give_v it_o in_o electuary_n fine_o divide_v among_o other_o thing_n which_o they_o do_v so_o frequent_o that_o all_o electuary_n come_v to_o be_v call_v opiate_n this_o upon_o experience_n i_o suppose_v make_v galen_n say_v that_o opium_n be_v not_o safe_a alone_o but_o mix_v with_o other_o thing_n it_o become_v a_o good_a medionment_n 12._o wedelius_n say_v that_o it_o seldom_o cause_v ill_a effect_n when_o give_v in_o a_o fine_a powder_n with_o other_o thing_n yet_o be_v it_o the_o same_o in_o substance_n and_o to_o all_o intent_n but_o that_o the_o resinous_n part_v be_v segregated_a and_o scatter_a become_v more_o subduable_a and_o less_o liable_a to_o coalescence_n whereas_o if_o it_o be_v give_v alone_o in_o the_o form_n of_o a_o pill_n all_o the_o rosin_n fall_v together_o upon_o one_o part_n of_o the_o somach_n and_o there_o stick_v therefore_o crude_a or_o resinous_n opium_n shall_v never_o be_v give_v alone_o in_o the_o form_n of_o a_o pill_n 13._o the_o blunder_a ancient_n give_v wine_n to_o correct_v as_o they_o think_v the_o cold_a quality_n of_o opium_n find_v by_o experience_n that_o old_a generous_a wine_n take_v pretty_a free_o after_o opium_n do_v very_o much_o prevent_v those_o ill_a effect_n but_o it_o can_v not_o be_v by_o correct_v the_o cold_a quality_n of_o opium_n which_o it_o have_v not_o nor_o indeed_o for_o any_o imaginable_a reason_n but_o that_o be_v a_o sulphureous_a menstruum_fw-la it_o help_v the_o dissolution_n and_o digestion_n of_o the_o rosin_n and_o the_o more_o for_o be_v old_a as_o all_o know_v because_o more_o spirituous_a defecated_a and_o vigorous_a whereas_o have_v it_o not_o be_v for_o that_o reason_n wine_n must_v have_v rather_o increase_v its_o effect_n than_o otherwise_o as_o be_v a_o opiate_n 14._o it_o be_v for_o the_o same_o reason_n that_o a_o tincture_n of_o opium_n in_o spirit_n of_o wine_n be_v find_v to_o be_v much_o safe_a than_o the_o extract_v make_v out_o of_o it_o though_o the_o substance_n be_v the_o same_o because_o that_o in_o the_o tincture_n the_o particle_n of_o the_o rosin_n be_v fine_o divide_v and_o scatter_v and_o so_o subduable_a and_o not_o like_a to_o stick_v to_o the_o coat_n of_o the_o stomach_n 15._o opium_n in_o clyster_n have_v kill_v people_n by_o slick_v to_o the_o intestinum_fw-la rectum_fw-la whereas_o it_o have_v nothing_o in_o it_o as_o be_v apparent_a from_o the_o premise_n that_o can_v hurt_v by_o stick_v to_o they_o but_o its_o resinous_n part_n much_o more_o than_o may_v it_o grieve_v the_o more_o exquisite_o sensile_a stomach_n by_o the_o same_o mean_n from_o what_o be_v say_v it_o will_v be_v obvious_a how_o due_o to_o prepare_v and_o correct_v opium_n though_o there_o have_v be_v no_o true_a conception_n thereof_o
have_v spend_v month_n in_o prepare_v the_o sapo_n tartareus_fw-la to_o correct_v opium_n when_o they_o may_v with_o the_o hundred_o part_n of_o the_o trouble_v and_o forty_o part_n of_o the_o time_n whole_o have_v take_v away_o the_o pernicious_a part_n by_o aqueous_a menstruum_n which_o they_o only_o pretend_v to_o correct_v by_o the_o sapo_n tartareus_fw-la though_o i_o allow_v it_o for_o the_o reason_n aforesaid_a to_o be_v a_o good_a corrector_n yet_o can_v it_o equal_v the_o total_a separation_n of_o the_o pernicious_a part_n i_o be_o of_o opinion_n upon_o my_o best_a thought_n and_o some_o experience_n that_o intimate_o mix_v and_o subdue_a opium_n with_o good_a white_a soap_n may_v for_o the_o reason_n aforesaid_a prove_v a_o good_a and_o ready_a corrector_n or_o preventer_n of_o the_o adhesion_n of_o the_o resinous_a part_n of_o opium_n to_o the_o stomach_n much_o conduce_v to_o its_o dissolution_n or_o digestion_n therein_o and_o nimble_a slip_n out_o of_o it_o and_o thereby_o prevent_v all_o the_o ill_a effect_n of_o opium_n which_o it_o cause_v by_o the_o adhesion_n and_o indigestibleness_n of_o its_o rosin_n of_o the_o second_o sort_n of_o preparation_n of_o opium_n wherein_o its_o rosin_n remain_v whole_o unaltered_a in_o its_o nature_n yet_o become_v safe_a by_o divide_v it_o etc._n etc._n this_o be_v main_o if_o not_o altogether_o do_v by_o a_o fine_a and_o through_o division_n of_o the_o resinous_a part_n of_o opium_n and_o keep_v they_o afterward_o from_o a_o coalescence_n in_o and_o adhesion_n to_o the_o stomach_n by_o which_o mean_n they_o become_v digestible_a or_o at_o least_o passable_a without_o offence_n this_o may_v be_v do_v 1._o by_o torrefaction_n till_o the_o opium_n be_v very_o friable_a and_o then_o fine_o powder_a it_o and_o mix_v it_o with_o such_o thing_n as_o be_v of_o good_a consistence_n etc._n etc._n to_o keep_v the_o part_n of_o opium_n from_o a_o coalescence_n as_o in_o venice_n treacle_n mithridate_n diascordium_n the_o philonium_n etc._n etc._n this_o be_v the_o way_n and_o method_n that_o the_o ancient_n use_v which_o cause_v galen_n to_o say_v that_o opium_n alone_o that_o be_v undivided_a and_o unmixed_a with_o other_o thing_n to_o prevent_v its_o coalescence_n etc._n etc._n be_v dangerous_a but_o mix_v with_o other_o thing_n be_v salutiferous_a which_o they_o find_v by_o experience_n not_o know_v the_o cause_n but_o attribute_v the_o safety_n thereof_o to_o something_o among_o the_o many_o ingredient_n as_o a_o corrector_n of_o the_o opium_n hence_o it_o be_v that_o they_o put_v small_a quantity_n thereof_o into_o electuary_n make_v of_o many_o and_o much_o other_o thing_n that_o keep_v the_o particle_n asunder_o which_o they_o do_v so_o common_o that_o at_o last_o all_o electuary_n be_v call_v opiate_n thus_o we_o have_v those_o composition_n above_o name_v which_o be_v safe_o use_v for_o the_o reason_n aforesaid_a not_o that_o any_o thing_n therein_o correct_v i_o know_v not_o what_o poisonous_a or_o narcotick_a quality_n in_o opium_n but_o that_o the_o other_o ingredient_n divide_v its_o rosin_n and_o afterward_o keep_v its_o particle_n from_o coalescence_n and_o adhesion_n 2._o dissolution_n of_o opium_n in_o spirit_n of_o wine_n or_o such_o sulphureous_a spirit_n which_o fine_o divide_v the_o rosin_n and_o use_v the_o bare_a tincture_n before_o the_o resinous_a particle_n be_v again_o compact_v as_o in_o extract_n etc._n etc._n may_v be_v of_o use_n if_o due_o administer_v but_o here_o a_o caution_n be_v to_o be_v use_v that_o you_o take_v it_o not_o in_o or_o drink_v any_o aqueous_a or_o phlegmatic_a liquid_a with_o it_o or_o before_o or_o after_o it_o in_o two_o or_o three_o hour_n which_o if_o you_o do_v the_o resinous_a particle_n will_v be_v precipitate_v thereby_o and_o so_o stick_v to_o the_o bottom_n tom_fw-mi of_o the_o stomach_n cause_v thereby_o the_o usual_a ill_a effect_n of_o vomit_v anxiety_n etc._n etc._n therefore_o it_o shall_v be_v give_v only_o in_o a_o spirituous_a liquid_a note_v also_o that_o if_o you_o give_v a_o solution_n thereof_o in_o any_o lixivium_n you_o take_v care_v not_o to_o dilate_v it_o by_o any_o mean_n by_o aqueous_a liquid_n in_o two_o hour_n before_o or_o after_o you_o take_v it_o for_o then_o there_o be_v but_o little_a lixivial_a salt_n in_o proportion_n to_o the_o liquid_a the_o resinous_a part_n be_v let_v go_v and_o precipitate_v to_o the_o bottom_n of_o the_o stomach_n as_o in_o the_o case_n of_o the_o spirit_n of_o wine_n so_o dilate_v of_o which_o i_o have_v see_v a_o very_a convince_a instance_n for_o one_o that_o have_v a_o esteem_n of_o lixivial_o in_o this_o case_n not_o only_o according_a to_o helmont_n and_o the_o common_a cry_n to_o correct_v opium_n but_o also_o to_o extract_v its_o virtue_n the_o more_o effectual_o make_v a_o tincture_n of_o opium_n in_o water_n lixiviate_v with_o salt_n of_o wormwood_n whereof_o he_o take_v the_o quantity_n that_o he_o have_v see_v i_o give_v of_o my_o liquid_a panacea_fw-la in_o a_o coffee-dish_n full_a of_o water_n which_o precipitate_v the_o rosin_n in_o the_o stomach_n cause_v he_o to_o vomit_v in_o about_o a_o hour_n after_o and_o continue_v so_o to_o do_v for_o about_o 15_o hour_n by_o which_o you_o plain_o see_v that_o the_o great_a secret_a of_o lixivial_o to_o correct_v opium_n lie_v mere_o in_o its_o division_n of_o the_o rosin_n thereof_o as_o in_o the_o case_n of_o spirit_n of_o wine_n and_o powder_a it_o and_o afterward_o keep_v its_o particle_n asunder_o during_o its_o stay_n at_o stomach_n which_o the_o sapo_n tartareus_fw-la do_v and_o probable_o other_o soap_n may_v do_v very_o well_o for_o the_o several_a reason_n aforesaid_a 3._o dissolution_n of_o opium_n in_o the_o yolk_n of_o a_o rear_n new_o lay_v egg_n by_o pound_v the_o dose_n that_o you_o intend_v to_o take_v with_o a_o little_a quantity_n of_o the_o yolk_n till_o both_o be_v thorough_o mix_v and_o then_o take_v it_o in_o the_o remain_a part_n of_o the_o yolk_n by_o which_o mean_v you_o not_o only_o fine_o divide_v the_o resinous_a part_n of_o the_o opium_n while_o the_o yolk_n of_o the_o egg_n intimate_o mix_v with_o they_o as_o it_o do_v with_o other_o rosin_n and_o turpentine_n but_o send_v along_o with_o it_o into_o the_o stomach_n what_o be_v digestible_a in_o itself_o and_o more_o and_o more_o divide_v and_o separate_v the_o resinous_a part_n and_o high_o contribute_v to_o their_o final_a dissolution_n and_o digestion_n so_o that_o i_o doubt_v not_o but_z you_o will_v find_v this_o new_a ready_a and_o agreeable_a mean_n as_o good_a if_o not_o better_o all_o thing_n consider_v than_o the_o former_a and_o even_o equal_a to_o the_o sapo_n tartareus_fw-la by_o what_o be_v say_v though_o short_a you_o may_v because_o it_o be_v the_o clear_a truth_n of_o thing_n judge_v of_o the_o goodness_n of_o all_o preparation_n of_o opium_n and_o 1._o that_o resinous_a thing_n shall_v not_o be_v add_v to_o opium_n because_o such_o like_o its_o own_o rosin_n render_v it_o more_o indigestible_a and_o apt_a to_o stick_v at_o stomach_n hence_o it_o be_v that_o the_o styrax_fw-mi pill_n have_v resinous_a thing_n in_o it_o and_o crude_a opium_n do_v so_o often_o cause_v dismal_a effect_n though_o forsooth_o much_o esteem_v for_o the_o lung_n cough_n defluxion_n etc._n etc._n for_o have_v such_o balsamic_a resinous_a thing_n as_o styrax_n and_o olibanum_n in_o it_o whereas_o the_o benefit_n be_v from_o the_o opium_n have_v dr._n bates_n know_v the_o cause_n of_o the_o mischief_n of_o opium_n he_o will_v never_o have_v put_v benjamin_n in_o his_o pacifick_n pill_n 2._o that_o all_o preparation_n make_v of_o extract_n in_o spirit_n of_o wine_n be_v to_o be_v reject_v such_o extract_v be_v much_o worse_a than_o crude_a opium_n and_o experimental_o find_v to_o be_v so_o therefore_o our_o common_a london_n laudanum_n be_v make_v of_o opium_n prepare_v in_o spirit_n of_o wine_n be_v no_o commendable_a preparation_n though_o so_o much_o use_v and_o cry_v up_o which_o also_o experience_n prove_v in_o that_o it_o sometime_o cause_v the_o ill_a effect_n of_o opium_n when_o give_v alone_o in_o a_o good_a do_v you_o will_v find_v more_o of_o these_o matter_n when_o you_o come_v to_o chap._n 29._o which_o consist_v of_o general_a rule_n and_o caution_n concern_v the_o use_n of_o opium_n therefore_o though_o i_o may_v add_v some_o useful_a observation_n i_o put_v a_o end_n to_o this_o matter_n at_o present_a for_o that_o reason_n and_o because_o what_o be_v to_o be_v true_o do_v in_o the_o preparation_n of_o opium_n be_v very_o evident_a from_o what_o be_v say_v since_o the_o cause_n of_o the_o ill_a effect_n of_o opium_n be_v now_o certain_o know_v to_o be_v its_o rosin_n to_o the_o separation_n or_o due_a alteration_n of_o which_o so_o as_o to_o cause_v it_o to_o pass_v the_o stomach_n without_o adhesion_n or_o offence_n by_o
darkness_n of_o the_o eye_n see_v thing_n double_a various_a colour_n before_o the_o eye_n loss_n of_o feel_v ease_n from_o pain_n etc._n etc._n deadness_n of_o the_o eye_n to_o the_o view_n dilatation_n of_o the_o pupilla_fw-la efflorescence_n of_o the_o skin_n laxity_n of_o the_o low_a jaw_n intumescence_n and_o laxity_n of_o the_o lip_n falter_v of_o the_o tongue_n sardonick_a laughter_n laxity_n and_o weakness_n of_o all_o part_n a_o general_a ineptitude_n to_o motion_n failure_n in_o make_v water_n go_v to_o stool_n and_o in_o all_o thing_n that_o require_v strength_n contraction_n motion_n etc._n etc._n difficulty_n of_o breathe_v a_o wide_a and_o slow_a pulse_n a_o condition_n in_o general_a very_a like_o that_o of_o drunkenness_n which_o also_o proceed_v from_o relaxation_n second_o when_o you_o be_v satisfy_v that_o relaxation_n be_v the_o cause_n use_v all_o mean_n to_o procure_v a_o due_a contraction_n of_o all_o part_n which_o be_v to_o be_v do_v 1._o by_o remove_v the_o cause_n of_o the_o relaxation_n 2._o by_o use_v all_o good_a mean_n for_o contraction_n first_o therefore_o give_v a_o brisk_a quick_a and_o strong_a vomit_n both_o to_o discharge_v the_o opiate_n and_o cause_n contraction_n of_o part_n by_o a_o grievous_a sensation_n proportion_n it_o to_o the_o deadness_n stupidity_n or_o sleepiness_n of_o the_o person_n so_o as_o to_o give_v it_o of_o twice_o the_o ordinary_a strength_n of_o vomit_n in_o case_n there_o be_v great_a danger_n from_o those_o symptom_n and_o that_o they_o be_v of_o a_o high_a nature_n after_o the_o person_n have_v vomit_v 3_o or_o 4_o time_n or_o so_o often_o as_o that_o you_o may_v judge_v the_o stomach_n well_o clear_v of_o the_o opiate_n give_v half_o a_o ounce_n of_o cream_n of_o tartar_n fine_o powder_v in_o thin_a broth_n whey_n water_n small_a beer_n or_o any_o convenient_a liquid_a which_o will_v correct_v the_o opiate_n if_o any_o remain_v at_o stomach_n turn_v the_o vomit_n to_o a_o purger_n to_o clear_v the_o intestine_n also_o and_o contribute_v much_o to_o the_o contraction_n of_o part_n which_o you_o must_v always_o have_v in_o your_o thought_n as_o the_o roll_a intention_n in_o this_o case_n therefore_o second_o you_o must_v use_v contracter_n all_o the_o time_n the_o chief_a of_o which_o be_v cold_a grievous_a sensation_n or_o pain_n terror_n fear_v voluntary_a motion_n and_o acid_n which_o last_n can_v be_v so_o well_o use_v during_o the_o vomit_v lest_o they_o stop_v it_o therefore_o especial_o if_o the_o person_n be_v very_o stupid_a keep_v he_o very_o cold_a for_o he_o will_v hardly_o feel_v it_o nor_o take_v cold_a because_o the_o relaxation_n and_o the_o insensibleness_n of_o grievance_n by_o cold_a etc._n etc._n keep_v the_o pore_n open_a let_v he_o be_v if_o possible_a in_o some_o motion_n as_o walk_v hew_v saw_v knock_v tug_v etc._n etc._n the_o more_o violent_a it_o be_v the_o better_a because_o it_o cause_v more_o contraction_n and_o agitation_n to_o prevent_v sopor_n to_o force_v he_o to_o motion_n if_o need_v be_v prick_a pinch_a or_o whip_v he_o about_o the_o leg_n etc._n etc._n will_v be_v of_o good_a use_n because_o grievous_a sensation_n add_v defensive_a contraction_n which_o be_v the_o great_a sort_n to_o that_o of_o the_o intentive_a contraction_n by_o voluntary_a motion_n these_o mean_n fail_v he_o shall_v be_v expose_v stark_o naked_a to_o the_o cold_a air_n and_o in_o desperate_a case_n throw_v sudden_o at_o unaware_o into_o cold_a water_n by_o which_o mean_v you_o cause_n terror_n surprise_v and_o cold_a which_o be_v the_o high_a and_o most_o forcible_a contracter_n to_o conspire_v to_o the_o contraction_n of_o part_n hence_o it_o be_v that_o drunken_a people_n who_o be_v so_o from_o relaxation_n become_v sober_a as_o in_o a_o moment_n by_o that_o mean_n all_o the_o time_n but_o during_o the_o vomit_v let_v he_o use_v cold_a acid_n in_o great_a plenty_n and_o very_o manifest_o acid_a for_o they_o will_v not_o only_o contribute_v to_o contraction_n but_o very_o much_o correct_v the_o opiate_n to_o this_o end_n juice_n of_o orange_n or_o lemon_n verjuice_n or_o water_n acidulate_v to_o a_o good_a degree_n by_o verjuice_n vinegar_n juice_n of_o lemon_n spirit_n of_o vitriol_n sulphur_n or_o the_o like_a will_v be_v very_o proper_a where_o you_o have_v not_o the_o convenience_n to_o plunge_v they_o into_o cold_a water_n as_o be_v direct_v dash_v or_o pump_v very_o cold_a water_n or_o water_n with_o a_o four_o part_n of_o vinegar_n upon_o their_o naked_a body_n will_v be_v of_o great_a use_n especial_o if_o surprise_o do_v to_o cause_v the_o more_o terror_n and_o concern_v these_o thing_n may_v be_v do_v more_o or_o lâ—ss_o as_o cause_n may_v require_v which_o must_v be_v leave_v to_o the_o discretion_n of_o the_o present_a physician_n or_o friend_n and_o standard_n by_o in_o case_n there_o be_v no_o physician_n i_o only_o caution_n that_o contracter_n shall_v not_o be_v use_v too_o spare_o and_o that_o you_o shall_v never_o cease_v to_o advance_v in_o the_o use_n of_o they_o till_o you_o perceive_v their_o good_a effect_n and_o then_o to_o continue_v they_o as_o occasion_n require_v note_v that_o the_o case_n may_v well_o happen_v that_o the_o rosin_n may_v stick_v at_o stomach_n and_o yet_o no_o sign_n or_o symptom_n appear_v but_o those_o of_o relaxation_n by_o reason_n that_o the_o feel_n at_o stomach_n may_v thereby_o be_v disable_v to_o take_v any_o notice_n of_o it_o to_o be_v sure_a of_o this_o you_o have_v no_o other_o mean_n because_o the_o symptom_n and_o effect_n of_o grievous_a sensation_n can_v appear_v where_o it_o be_v not_o for_o the_o aforesaid_a reason_n but_o to_o examine_v whether_o the_o opiate_n be_v a_o resinous_a one_o as_o crude_a opium_n extract_v out_o of_o spirit_n of_o wine_n or_o the_o like_a for_o than_o you_o may_v conclude_v especial_o if_o they_o be_v give_v in_o a_o massy_a solid_a form_n as_o that_o of_o pill_n etc._n etc._n without_o sever_n the_o particle_n of_o the_o rosin_n by_o other_o thing_n as_o the_o yolk_n of_o a_o egg_n etc._n etc._n that_o the_o rosin_n may_v in_o all_o probability_n stick_v at_o stomach_n though_o its_o symptom_n do_v not_o appear_v for_o the_o aforesaid_a reason_n in_o such_o a_o case_n the_o best_a advice_n that_o i_o can_v give_v be_v external_o to_o use_v all_o contract_n mean_v as_o be_v direct_v and_o internal_o the_o mean_v prescribe_v for_o dissolution_n of_o the_o rosin_n for_o you_o will_v thereby_o answer_v both_o intention_n failure_n of_o make_v water_n often_o happen_v in_o these_o case_n which_o you_o may_v general_o help_v by_o only_o clap_v the_o scrotum_fw-la to_o the_o cold_a chamber_n pot_n or_o into_o cold_a water_n and_o if_o that_o will_v not_o do_v put_v some_o vinegar_n into_o the_o water_n and_o that_o fail_v he_o must_v be_v strip_v and_o cold_a water_n pump_v or_o dash_v upon_o the_o region_n of_o the_o bladder_n iii_o to_o cure_v the_o ill_a effect_n of_o a_o long_a and_o lavish_a use_n of_o opium_n these_o effect_n as_o you_o may_v easy_o observe_v if_o you_o take_v a_o view_n of_o they_o where_o they_o be_v enumerate_v in_o chap._n 6._o be_v either_o 1._o from_o a_o overmuch_o and_o habitual_a relaxation_n of_o part_n as_o weakness_n a_o moapish_a disposition_n diminution_n of_o appetite_n weakness_n of_o digestion_n dropsy_n weakness_n of_o memory_n etc._n etc._n or_o 2._o from_o acrimony_n as_o frequent_a irritation_n to_o make_v water_n priapism_n erection_n of_o the_o penis_n fruitless_a inclination_n to_o venery_n etc._n etc._n in_o this_o case_n as_o in_o that_o of_o old_a drunkard_n which_o be_v much_o the_o same_o there_o be_v no_o good_a to_o be_v do_v till_o the_o habitual_a cause_n be_v remove_v viz._n the_o take_v of_o opium_n which_o sudden_o to_o leave_v off_o be_v as_o be_v show_v very_o dangerous_a therefore_o in_o order_n to_o leave_v it_o off_o safe_o 1._o you_o must_v stop_v your_o hand_n and_o not_o increase_v the_o do_v that_o be_v take_v by_o which_o mean_v it_o will_v come_v gradual_o to_o have_v little_a or_o no_o effect_n 2._o when_o you_o find_v that_o it_o be_v come_v to_o that_o pass_n your_o work_n be_v half_o do_v then_o only_o lessen_v it_o 100th_o part_n every_o day_n till_o you_o come_v to_o take_v none_o at_o all_o 3._o if_o during_o this_o retrograde_a course_n you_o find_v any_o faintness_n drink_v a_o glass_n of_o good_a stomach-wine_n toties_fw-la quoties_fw-la as_o gentian_n or_o centary_a wine_n or_o the_o like_a make_v by_o infusion_n in_o claret_n or_o if_o you_o want_v such_o a_o glass_n of_o the_o claret_n itself_o which_o thing_n will_v excite_v the_o spirit_n and_o help_v digestion_n 4._o when_o you_o have_v quite_o end_v the_o take_v of_o opium_n continue_v to_o use_v such_o wine_n when_o you_o be_v faint_a and_o every_o morning_n take_v in_o a_o glass_n of_o
gentian_a wine_n two_o dram_fw-la of_o the_o chalybeate_a wine_n describe_v in_o the_o london_n dispensatory_a increase_v about_o a_o scruple_n every_o day_n till_o you_o come_v to_o half_a a_o ounce_n which_o take_v for_o two_o month_n at_o least_o afterward_o decrease_v as_o you_o increase_v till_o you_o come_v to_o one_o drachm_n and_o so_o give_v over_o but_o if_o you_o find_v oâ—osion_n you_o may_v continue_v that_o course_n long_o or_o as_o long_o as_o your_o physician_n think_v fit_a after_o all_o you_o may_v use_v a_o glass_n of_o claret_n when_o faint_a but_o be_v sure_a to_o be_v moderate_a and_o not_o run_v from_o one_o excess_n to_o another_o as_o for_o the_o acrimony_n of_o blood_n that_o be_v more_o during_o the_o take_v of_o opium_n and_o will_v soon_o after_o gradual_o wear_v off_o especial_o by_o the_o course_n direct_v if_o not_o camphire_n be_v the_o adequate_a remedy_n of_o which_o with_o equal_a part_n of_o white_a rosin_n and_o q._n s._n of_o mucilage_n of_o gum._n tragac._n you_o may_v make_v pill_n of_o â—_o grain_n weight_n take_v 4_o of_o they_o every_o night_n at_o bedtime_n in_o a_o rear_n yolk_n of_o a_o egg_n as_o long_o as_o it_o be_v necessary_a for_o camphire_n by_o its_o fine_a sulphur_n correct_v the_o volatile_a acrimony_n of_o cantharides_n opium_n etc._n etc._n and_o so_o allay_v titillation_n to_o venery_n etc._n etc._n as_o be_v observe_v iv_o the_o ill_a effect_n of_o a_o sudden_a leave_v off_o of_o opium_n as_o anxiety_n distress_n depression_n of_o spirit_n which_o as_o be_v say_v be_v very_o dangerous_a be_v remedy_v no_o other_o way_n but_o either_o 1._o by_o return_v to_o the_o use_v of_o opium_n which_o be_v a_o most_o certain_a cure_n and_o afterward_o if_o you_o please_v give_v over_o the_o use_n of_o it_o after_o the_o manner_n that_o i_o direct_v which_o you_o will_v find_v to_o be_v safe_a nor_o can_v i_o advise_v you_o to_o trust_v any_o other_o method_n of_o leave_v it_o off_o unless_o it_o be_v 2._o by_o substitute_v wine_n instead_o of_o opium_n which_o be_v not_o quite_o so_o safe_a or_o certain_a your_o best_a method_n of_o use_v it_o be_v to_o drink_v a_o good_a glass_n of_o it_o so_o often_o as_o to_o keep_v the_o comfort_n thereof_o at_o stomach_n continual_o that_o so_o it_o may_v answer_v the_o more_o permanent_a effect_n of_o opium_n and_o keep_v you_o from_o a_o faint_a condition_n but_o see_v also_o that_o this_o course_n be_v not_o convenient_a to_o be_v continue_v long_o you_o must_v gradual_o lessen_v the_o do_v of_o this_o as_o you_o be_v direct_v to_o do_v that_o of_o opium_n till_o you_o come_v to_o take_v none_o or_o at_o least_o a_o moderate_a and_o wholesome_a quantity_n note_v that_o if_o such_o as_o use_v to_o take_v opium_n be_v even_o almost_o expire_a for_o want_n of_o it_o you_o must_v to_o prevent_v imminent_a death_n give_v a_o liquid_a preparation_n thereof_o to_o the_o value_n of_o what_o the_o person_n be_v use_v to_o take_v in_o a_o cordial_a vehicle_n as_o spirit_n of_o wine_n brandy_n or_o the_o like_a because_o such_o hot_a spirituous_a vehicles_n do_v as_o have_v be_v show_v immediate_o give_v some_o comfort_n by_o actuate_a and_o warm_v our_o spirit_n till_o the_o opium_n come_v to_o operate_v which_o will_v not_o be_v long_o because_o it_o be_v in_o a_o liquid_a form_n if_o you_o find_v the_o person_n sink_v notwithstanding_o he_o may_v be_v keep_v up_o by_o repeat_v the_o brandy_n or_o cordial_n without_o any_o opium_n in_o it_o till_o the_o opiate_n operate_v which_o will_v certain_o by_o god_n help_n set_v he_o right_n in_o case_n it_o do_v but_o begin_v to_o operate_v before_o he_o be_v dead_a see_v the_o philos._n transact_v for_o june_n july_n august_n 1696._o note_v that_o it_o be_v a_o very_a false_a imagination_n that_o author_n have_v of_o the_o turk_n capacity_n by_o nature_n climate_n or_o the_o like_a to_o take_v more_o opium_n or_o in_o great_a quantity_n than_o we_o may_v but_o that_o they_o make_v more_o use_n of_o it_o and_o by_o that_o mean_n come_v to_o take_v 2_o or_o 3_o dram_fw-la a_o day_n for_o they_o begin_v with_o such_o small_a quantity_n as_o we_o common_o give_v till_o by_o a_o long_a custom_n of_o take_v it_o they_o come_v to_o take_v the_o say_a quantity_n which_o be_v but_o small_a in_o comparison_n of_o what_o several_a english_a people_n that_o have_v be_v use_v to_o it_o do_v or_o have_v take_v as_o i_o can_v name_v several_a to_o you_o if_o i_o have_v not_o reason_n to_o the_o contrary_a however_o i_o be_o at_o liberty_n to_o tell_v you_o the_o quantity_n though_o i_o must_v forbear_v name_v the_o person_n some_o have_v daily_o take_v 2_o 3_o 4_o 5_o 6_o dram_fw-la nay_o i_o have_v hear_v of_o some_o that_o have_v take_v a_o ounce_n a_o day_n and_o of_o one_o that_o take_v two_o ounce_n whereas_o the_o learned_a and_o curious_a dr._n edward_n smith_n can_v find_v none_o about_o smyrna_n who_o take_v above_o 3_o dram_fw-la a_o day_n all_o this_o be_v most_o agreeable_a to_o reason_n and_o the_o whole_a current_n of_o my_o discourse_n viz._n that_o it_o can_v be_v better_o bear_v in_o cold_a than_o hot_a wether_n and_o consequent_o in_o cold_a than_o hot_a climate_n by_o firm_a flesh_v person_n than_o such_o as_o have_v soft_a and_o flaccid_a flesh_n as_o the_o southern_a people_n have_v in_o comparison_n of_o the_o northern_a and_o such_o as_o inhabit_v cold_a country_n therefore_o you_o may_v be_v sure_a that_o such_o as_o inquire_v into_o the_o cause_n why_o the_o turk_n and_o other_o eastern_a people_n can_v take_v great_a quantity_n than_o we_o can_v seek_v for_o the_o reason_n of_o thing_n before_o they_o know_v the_o fact_n nay_o when_o the_o fact_n be_v quite_o contrary_a to_o what_o they_o build_v upon_o we_o may_v as_o well_o expect_v edify_v discourse_n from_o they_o that_o inquire_v why_o fire_n be_v cold_a water_n dry_a and_o the_o like_a as_o from_o such_o as_o suppose_v thing_n contrary_a to_o true_a and_o sensible_a experience_n chap._n xxix_o some_o general_a rule_n caution_n &c_n &c_n concern_v the_o use_n of_o opium_n though_o there_o be_v hardly_o any_o rule_n caution_n or_o thing_n worthy_a of_o observation_n concern_v the_o use_n of_o opium_n but_o what_o be_v imply_v or_o easy_o inferable_a from_o what_o have_v be_v say_v nor_o now_o that_o the_o true_a nature_n of_o opium_n be_v discover_v can_v there_o be_v such_o fear_n and_o jealoufy_v which_o multiply_v caution_n concern_v the_o administration_n thereof_o for_o every_o one_o may_v now_o easy_o see_v wherein_o its_o danger_n and_o benefit_n lie_v yet_o because_o a_o chapter_n of_o rule_n and_o caution_n may_v be_v expect_v as_o be_v usual_a and_o to_o have_v a_o single_a view_n of_o such_o as_o lie_v more_o scatter_v and_o not_o so_o ready_o find_v in_o the_o body_n of_o the_o book_n i_o will_v to_o introduce_v the_o use_n of_o opium_n with_o more_o clearness_n and_o perfect_a security_n give_v you_o a_o collection_n of_o general_a rule_n and_o caution_n concern_v its_o use_n whereof_o some_o be_v mention_v and_o most_o inferable_a from_o the_o premise_n i._o as_o to_o its_o substance_n 1._o it_o shall_v be_v always_o give_v free_v from_o its_o resinous_n part_n if_o you_o can_v get_v such_o a_o preparation_n 2._o it_o be_v also_o neat_a and_o convenient_a that_o it_o shall_v be_v free_v from_o all_o its_o earth_n and_o dress_n 3._o never_o give_v opium_n but_o either_o so_o prepare_v or_o with_o its_o rosin_n so_o subdue_v segregated_a or_o alter_v as_o i_o have_v show_v in_o the_o safe_a preparation_n thereof_o iâ—_n follow_v that_o 4._o crude_a opium_n and_o extract_v make_v in_o sulphureous_a spirit_n be_v utter_o to_o be_v reject_v 5._o never_o give_v it_o mix_v or_o join_v with_o resinous_a thing_n as_o have_v be_v intimate_v 6._o never_o mix_v or_o join_v it_o with_o other_o opiate_n 1._o because_o none_o of_o they_o be_v so_o good_a 2._o because_o they_o be_v not_o so_o well_o know_v 3._o because_o it_o make_v the_o do_v more_o uncertain_a 4._o because_o those_o other_o opiate_n be_v use_v unprepared_a 7._o pil._n e_o styrace_n because_o make_v of_o resinous_a opium_n join_v with_o resinous_a thing_n as_o styrax_fw-la calam_fw-la and_o olibanum_n be_v a_o insufferable_a preparation_n though_o commend_v and_o therefore_o have_v frequent_a ill_a effect_n to_o my_o knowledge_n 8._o pil._n â—_o cynoglossâ_fw-la be_v such_o another_o have_v two_o opiate_n in_o it_o beside_o opium_n extract_v out_o of_o spirit_n of_o wine_n which_o be_v far_o worse_a than_o crude_a opium_n though_o by_o the_o way_n of_o eminence_n call_v opium_n prepare_v in_o our_o dispensatory_a styrax_n calam_fw-la and_o olibanum_n which_o be_v resinous_a 9_o laudan_n lond._n be_v also_o a_o ill_a preparation_n as_o have_v the_o
opium_n extract_v out_o of_o spirit_n of_o wine_n to_o make_v it_o worse_o than_o when_o crude_a therefore_o have_v sometime_o ill_a effect_n especial_o when_o use_v alone_o in_o the_o form_n of_o a_o pill_n in_o a_o large_a do_v as_o be_v say_v 10._o philonium_fw-la magistrale_fw-la be_v also_o to_o be_v reject_v because_o the_o opium_n be_v prepare_v in_o spirit_n of_o wine_n and_o benjamin_n add_v which_o be_v resinous_a 11._o philon._n rom._n &_o persic_a be_v tolerable_a because_o the_o opium_n be_v disgregated_a and_o mix_v as_o galen_n will_v have_v it_o among_o much_o and_o several_a other_o thing_n which_o keep_v its_o resinous_a part_n from_o coalescence_n ii_o as_o to_o its_o form_n 1._o a_o pilular_a form_n of_o crude_a opium_n or_o any_o resinous_a preparation_n thereof_o wherein_o the_o rosin_n be_v not_o due_o subdue_v segregated_a alter_v or_o correct_v be_v as_o have_v be_v show_v the_o most_o pernicious_a 2._o the_o form_n of_o a_o electuary_n be_v commendable_a it_o be_v in_o small_a quantity_n mix_v therein_o with_o many_o or_o much_o other_o thing_n that_o prevent_v the_o coalescence_n of_o the_o râ—sin_n we_o particle_n 3._o a_o liquid_a form_n be_v general_o good_a because_o the_o part_n as_o in_o a_o tincture_n of_o opium_n in_o spirit_n of_o wine_n be_v sever_v and_o segiegated_a yet_o it_o be_v not_o so_o very_o safe_a where_o the_o râ—sin_n be_v not_o separate_v because_o if_o care_n be_v not_o take_v as_o have_v be_v direct_v the_o resinous_a particle_n may_v be_v precipitate_v at_o stomach_n and_o so_o coalesce_v and_o stick_v to_o it_o 4._o the_o operation_n of_o opium_n be_v quick_a in_o a_o liquid_a form_n but_o more_o last_a in_o a_o solid_a form_n especial_o if_o the_o opium_n be_v resinous_a which_o though_o noxious_a in_o general_n yet_o have_v the_o advantage_n of_o duration_n where_o it_o may_v be_v bear_v as_o in_o person_n of_o a_o robu_v texture_n and_o good_a digestion_n or_o where_o custom_n have_v take_v off_o its_o grievounsess_n as_o you_o find_v in_o habitual_a tobaco-taking_a etc._n etc._n 5._o the_o liquid_a panacea_fw-la of_o opium_n be_v better_a for_o alteration_n because_o it_o be_v the_o first_o fruit_n of_o the_o opium_n and_o more_o sincere_a and_o unaltered_a by_o fire_n than_o the_o solid_a but_o 6._o the_o solid_a panacea_fw-la be_v better_a where_o a_o stay_n at_o stomach_n and_o the_o intestine_n be_v convenient_a as_o in_o stop_v of_o vomit_v looseness_n etc._n etc._n to_o be_v brief_a 7._o liquid_a form_n shall_v be_v always_o give_v in_o foul_a stomach_n where_o the_o digestion_n be_v weak_a in_o fever_n and_o when_o a_o nimble_a operation_n be_v requisite_a iii_o as_o to_o its_o dose_n 1._o the_o mean_a or_o middle_n do_v be_v general_o to_o be_v use_v and_o where_o there_o be_v no_o direction_n to_o the_o contrary_n 2._o the_o mean_a dose_n may_v serve_v except_o in_o violent_a pain_n or_o where_o much_o of_o the_o opiate_n be_v lose_v as_o it_o happen_v very_o often_o in_o vomit_v or_o looseness_n or_o to_o excite_v venery_n because_o those_o part_n be_v remote_a and_o require_v a_o very_a sensible_a titillation_n but_o as_o to_o these_o matter_n you_o will_v have_v particular_a direction_n in_o the_o respective_a case_n in_o the_o follow_a chapter_n that_o treat_v thereof_o in_o a_o special_a manner_n 3._o the_o do_v must_v be_v proportionable_o less_o in_o the_o fine_a and_o lax-textured_n child_n woman_n warm_a and_o moist_a wether_n weak_a stomach_n person_n much_o debilitate_a or_o overtired_n with_o work_n labour_n disease_n etc._n etc._n iv_o as_o to_o its_o vehicle_n 1._o it_o shall_v general_o unless_o there_o be_v particular_a cause_n to_o the_o contrary_a be_v pleasant_a and_o agreeable_a to_o the_o taste_n and_o stomach_n that_o it_o may_v rather_o conspire_v with_o the_o opiate_n to_o please_v the_o membrane_n etc._n etc._n than_o contradict_v the_o sensitive_a pleasure_n that_o it_o cause_n 2._o it_o shall_v not_o be_v a_o acid_n because_o it_o infringe_n the_o volatile_a nature_n of_o opium_n except_o some_o particular_a case_n require_v it_o which_o will_v be_v see_v hereafter_o 3._o it_o shall_v not_o be_v a_o volatilo-saline_a especial_o to_o cause_v sleep_n or_o because_o that_o may_v render_v it_o too_o acrimonious_a or_o pungent_a and_o so_o hinder_v sleep_n composure_n etc._n etc._n 4._o it_o shall_v not_o be_v lixivial_a because_o its_o fix_a nature_n oppose_v the_o volatile_a except_o it_o be_v where_o the_o opiate_n be_v resinous_a to_o help_v its_o dissolution_n therefore_o 5._o wine_n or_o ferment_v liquor_n cordial_n water_n or_o smooth_a and_o pleasant_a liquid_n as_o emulsion_n milk_n and_o water_n water_n and_o sugar_n etc._n etc._n will_v be_v the_o most_o proper_a general_o speak_v 6._o the_o resinous_a opiate_n shall_v be_v always_o give_v in_o sulphureous_a spirit_n wâ—ne_n or_o strong_a liquor_n or_o in_o a_o lixivial_a vehicle_n or_o rather_o in_o both_o mix_v or_o in_o a_o rear_n yolk_n of_o a_o egg_n or_o fine_o powder_v and_o well_o mix_v with_o electuary_n bolus_n conserve_n thick_a syrup_n pulp_n or_o any_o thing_n that_o be_v innocent_a and_o of_o a_o good_a consistence_n to_o keep_v the_o resinous_a particle_n asunder_o and_o to_o prevent_v their_o coalescence_n for_o which_o end_n i_o judge_v that_o good_a white_a sâ—p_n must_v be_v because_o of_o the_o alkali_n its_o slipp'riness_n and_o aptitude_n to_o join_v with_o the_o rosin_n a_o good_a vehicle_n the_o opium_n and_o scrape_n of_o the_o soap_n be_v mix_v with_o a_o little_a rose-water_n and_o what_o else_o you_o think_v fit_a to_o render_v they_o more_o acceptable_a by_o pound_v they_o in_o a_o mortar_n for_o a_o good_a while_n to_o a_o intimate_a mixture_n v._o as_o to_o time_n 1._o give_v the_o liquid_a form_n half_a a_o hour_n at_o least_o or_o a_o hour_n before_o the_o time_n you_o will_v have_v they_o operate_v 2._o give_v the_o solid_a form_n a_o hour_n or_o a_o hour_n and_o a_o half_a before_o you_o will_v have_v they_o operate_v it_o be_v very_o silly_a not_o to_o give_v they_o till_o the_o very_a time_n that_o they_o shall_v operate_v as_o it_o be_v usual_a at_o bedtime_n when_o they_o shall_v be_v then_o operate_a and_o cause_v sleepiness_n that_o the_o rest_n and_o ease_n of_o lie_v down_o may_v concur_v with_o it_o whereas_o if_o people_n be_v unapt_a to_o sleep_v as_o general_o they_o be_v who_o take_v opium_n they_o not_o take_v it_o till_o bedtime_n lie_v toss_v and_o tumble_v grow_v uneasy_a and_o restless_a and_o the_o bed_n hard_o and_o in_o a_o great_a part_n of_o the_o year_n too_o hot_a before_o the_o opium_n operate_v so_o that_o the_o opium_n can_v take_v effect_n by_o reason_n of_o disquietude_n so_o the_o person_n lie_v all_o or_o most_o part_n of_o the_o night_n without_o any_o sleep_n whereas_o if_o it_o be_v so_o give_v as_o to_o cause_v a_o great_a sleepiness_n by_o the_o time_n they_o go_v to_o bed_n their_o lie_v still_o a_o very_a little_a time_n which_o they_o be_v then_o apt_a to_o and_o the_o bed_n be_v soft_a easy_a cool_a and_o pleasant_a they_o immediate_o sleep_v and_o their_o spirit_n be_v compose_v continue_v their_o sleep_n all_o or_o most_o part_n of_o the_o night_n therefore_o i_o have_v often_o come_v where_o people_n have_v not_o sleep_v though_o they_o take_v a_o opiate_n at_o bedtime_n and_o give_v they_o the_o very_a same_o a_o convenient_a time_n before_o and_o they_o have_v sweet_o sleep_v to_o their_o heart_n desire_n and_o refreshment_n 4._o give_v opiate_n as_o to_o meal_n at_o least_o 3_o hour_n before_o and_o after_o they_o or_o about_o the_o middle_a time_n between_o they_o if_o it_o be_v in_o the_o daytime_n or_o when_o the_o stomach_n be_v near_o empty_a or_o but_o little_a or_o light_a matter_n in_o it_o which_o if_o gentle_a and_o agreeable_a will_v help_v man_n to_o sleep_v but_o great_a repletion_n and_o perfect_a emptiness_n or_o hunger_n which_o be_v a_o grievous_a sensation_n do_v disturb_v or_o hinder_v sleep_n 5._o opiate_n may_v and_o have_v prove_v inconvenient_a before_o or_o after_o let_v of_o blood_n and_o hemorrhage_n especial_o if_o the_o evacuation_n be_v large_a and_o sudden_a the_o reason_n be_v because_o though_o person_n be_v very_o dispirited_a and_o so_o much_o incline_v to_o sleep_n of_o themselves_o may_v sleep_v too_o much_o and_o dangerous_o and_o because_o opium_n relax_v hinder_v the_o vessel_n due_o to_o contract_v upon_o the_o remain_a blood_n which_o may_v cause_v a_o discontinuance_n of_o its_o stream_n by_o reason_n that_o the_o diminish_v blood_n may_v not_o suffice_v to_o fill_v up_o the_o relaxed_a vessel_n though_o this_o may_v seldom_o happen_v because_o the_o compressure_n of_o the_o air_n be_v appoint_v by_o most_o wise_a providence_n to_o close_v all_o our_o vessel_n in_o such_o case_n but_o it_o must_v be_v better_a do_v when_o the_o
of_o wine-drinker_n you_o may_v easy_o perceive_v by_o what_o have_v be_v say_v why_o our_o opium_n have_v so_o much_o filth_n in_o it_o why_o it_o taste_v sometime_o of_o a_o empyreum_fw-la or_o burn_v in_o not_o stir_v it_o well_o while_o it_o be_v boil_v into_o a_o consistence_n and_o not_o give_v it_o only_o a_o gentle_a heat_n when_o it_o begin_v to_o thicken_v gradual_o lessen_v the_o fire_n or_o let_v it_o convenient_o decay_n and_o go_v out_o of_o itself_o which_o be_v a_o very_a good_a way_n for_o such_o as_o have_v not_o other_o convenience_n for_o as_o the_o matter_n thicken_v the_o heat_n decline_v and_o so_o become_v safe_a from_o a_o taste_n of_o burn_v if_o the_o fire_n be_v due_o proportion_v but_o all_o this_o trouble_n be_v avoid_v by_o inspissate_v by_o the_o heat_n of_o the_o sun_n which_o be_v use_v in_o some_o country_n note_v that_o the_o poppy_n of_o which_o opium_n be_v make_v in_o all_o turkey_n egypt_n thebes_n etc._n etc._n be_v the_o great_a white_a poppy_n which_o grow_v very_o free_o in_o those_o part_n and_o as_o i_o be_o inform_v without_o any_o manure_n of_o the_o ground_n in_o some_o place_n certain_a it_o be_v that_o they_o now_o have_v whole_a field_n of_o that_o white_a poppy_n out_o of_o which_o they_o make_v the_o opium_n as_o be_v aforesaid_a by_o pound_v press_v boil_a etc._n etc._n chap._n ii_o of_o the_o election_n or_o choice_n of_o opium_n all_o opium_n be_v make_v in_o ancient_a time_n by_o the_o milky_a drop_n that_o fall_v out_o of_o the_o incision_n mention_v in_o the_o last_o chapter_n which_o be_v a_o natural_a and_o simple_a way_n make_v no_o difference_n in_o the_o opium_n but_o what_o nature_n itself_o do_v all_o their_o knowledge_n of_o the_o best_a opium_n consist_v in_o distinguish_v the_o theban_a from_o other_o opium_n which_o be_v not_o natural_o so_o good_a 1._o theban_a opium_n be_v of_o a_o light_a reddish_n yellow_a than_o other_o sort_n therefore_o some_o call_v it_o white_a opium_n not_o that_o it_o be_v abjolute_o white_a but_o only_o relative_o such_o in_o comparison_n with_o other_o kind_n of_o opium_n as_o we_o say_v white_a rosin_n in_o respect_n of_o other_o rosin_n tho'_o it_o be_v not_o white_a but_o only_o light_a colour_v than_o other_o rosin_n 2._o theban_a opium_n be_v most_o hot_a bitter_a and_o bite_v in_o taste_n from_o whence_o you_o may_v infer_v that_o the_o opium_n which_o have_v those_o quality_n in_o the_o high_a degree_n be_v the_o best_a 3._o it_o smell_v rank_o and_o vehement_o of_o the_o poppy_n which_o give_v you_o another_o good_a sign_n to_o judge_v of_o opium_n 4._o it_o burn_v with_o a_o clear_a flame_n than_o any_o other_o 5._o some_o say_v that_o it_o be_v weighty_a than_o other_o sort_n notwithstanding_o all_o which_o difference_n they_o do_v in_o time_n find_v way_n to_o adulterate_v it_o which_o be_v these_o 1._o they_o adulterate_v it_o with_o juice_n of_o glauciam_fw-la or_o apple_n of_o love_n this_o be_v discernible_a by_o the_o yellow_a tincture_n that_o it_o give_v to_o water_n and_o other_o menstruum_n whereas_o the_o theban_a and_o all_o true_a opium_n give_v a_o red_a tincture_n 2._o it_o be_v counterfeit_v with_o resinous_a thing_n this_o cheat_n be_v discoverable_a by_o its_o not_o be_v uniform_a nor_o so_o dissolvable_a in_o water_n as_o good_a opium_n 3._o it_o be_v mix_v with_o juice_n of_o lactuca_n sylvestris_n or_o wild_a endive_n leave_a lettuce_n this_o make_v it_o of_o a_o dull_a colour_n and_o not_o to_o smell_v so_o perfect_o and_o rank_o of_o the_o poppy_n 4._o it_o be_v sometime_o mix_v with_o the_o milky_a juice_n of_o spurge_n which_o be_v hot_a bitter_a and_o bite_a be_v hardly_o discernible_a but_o by_o its_o purge_n and_o disturb_v quality_n and_o somewhat_o less_o and_o different_a you_o may_v be_v sure_a that_o this_o and_o all_o the_o other_o mixture_n lessen_v its_o virtue_n as_o a_o opiate_n if_o consider_v in_o the_o same_o quantity_n because_o they_o must_v take_v up_o room_n in_o the_o mass_n but_o lactuca_n sylvestris_n be_v of_o the_o nature_n of_o opium_n make_v the_o loss_n of_o its_o virtue_n less_o discernible_a it_o be_v true_a that_o we_o have_v none_o of_o the_o opium_n that_o be_v gather_v by_o the_o milky_a drop_n out_o of_o the_o incision_n and_o therefore_o what_o be_v say_v do_v not_o much_o concern_v we_o as_o to_o that_o sort_n however_o these_o observation_n will_v enlighten_v we_o as_o to_o the_o opium_n that_o we_o now_o have_v of_o which_o i_o can_v find_v that_o there_o be_v much_o adulteration_n use_v because_o i_o suppose_v that_o it_o be_v now_o grow_v considerable_o cheap_a by_o reason_n of_o the_o vast_a quantity_n that_o be_v make_v with_o so_o much_o ease_n that_o it_o be_v not_o worth_a while_n to_o counterfeit_v it_o there_o be_v now_o great_a field_n of_o poppy_n in_o turkey_n so_o that_o our_o business_n will_v be_v rather_o to_o distinguish_v the_o sort_n than_o the_o adulteration_n tho'_o this_o shall_v not_o pass_v unregarded_a as_o far_o as_o it_o may_v concern_v we_o there_o be_v two_o sort_n bring_v over_o to_o we_o one_o from_o persia_n and_o the_o east-indies_n the_o other_o from_o turkey_n as_o from_o lesser_n asia_n or_o anatolia_n smyrna_n aleppo_n etc._n etc._n i._o that_o which_o be_v bring_v from_o east-india_n persia_n surat_n etc._n etc._n be_v as_o i_o be_o inform_v make_v of_o the_o leave_n and_o stem_n of_o the_o poppy_n and_o be_v 1._o more_o full_a of_o filth_n within_o it_o for_o the_o outside_n be_v not_o so_o much_o to_o be_v regard_v because_o of_o accident_n 2._o it_o be_v not_o so_o uniform_a smooth_a and_o supple_a but_o harsh_a and_o rugged_a 3._o it_o be_v not_o so_o ready_o dissolvable_a in_o water_n 4._o the_o indian_a be_v bring_v over_o in_o large_a piece_n 5._o it_o be_v not_o bring_v so_o wrap_v in_o leave_n as_o the_o turkey_n opium_n be_v bontius_n say_v that_o they_o make_v it_o of_o the_o stem_n and_o leave_n if_o so_o it_o must_v be_v much_o worse_a than_o the_o turkey_n opium_n that_o be_v make_v of_o the_o head_n and_o leave_n ii_o among_o those_o sort_n that_o be_v bring_v out_o of_o turkey_n and_o indeed_o any_o sort_n of_o opium_n 1._o that_o be_v best_a that_o be_v most_o bitter_a hot_a and_o bite_v 2._o the_o light_a white_a and_o clear_a its_o flame_n be_v when_o it_o burn_v the_o better_a it_o be_v 3._o the_o more_o uniform_a even_o smooth_a tough_a yield_a and_o comply_v it_o be_v to_o be_v wrought_v or_o bring_v to_o any_o form_n the_o better_a it_o be_v 4._o the_o more_o it_o give_v upon_z or_o against_o moist_a wether_n or_o in_o a_o moist_a air_n of_o any_o kind_n and_o the_o better_a speedy_a free_a and_o more_o perfect_o it_o dissolve_v in_o water_n the_o better_a it_o be_v 5._o the_o red_a the_o tincture_n be_v that_o it_o give_v in_o water_n spirit_n of_o wine_n or_o any_o menstruum_fw-la the_o better_a it_o be_v and_o it_o be_v never_o good_a if_o it_o give_v only_o a_o yellow_a tincture_n but_o note_v that_o even_o the_o best_a opium_n if_o you_o take_v but_o a_o very_a slight_a tincture_n thereof_o will_v appear_v yellowish_a especial_o in_o a_o white_a vessel_n therefore_o my_o meaning_n be_v that_o the_o red_a tincture_n opium_n cause_v in_o water_n quantity_n for_o quantity_n the_o better_a it_o be_v 6._o it_o shall_v have_v no_o taste_n or_o smell_v of_o a_o empyreum_fw-la or_o burn_v for_o that_o give_v it_o a_o nauseous_a taste_n and_o in_o some_o measure_n signify_v a_o loss_n of_o its_o virtue_n by_o burn_v tho'_o this_o may_v be_v inconsiderable_a 7._o the_o less_o filth_n it_o have_v on_o the_o inside_n the_o better_a it_o be_v 8._o the_o more_o it_o sparkle_v when_o cut_v and_o afterward_o breathe_v upon_o three_o or_o four_o time_n the_o true_a be_v the_o opium_n for_o those_o sparkle_a particle_n be_v its_o noble_a volatile_a salt_n or_o sal._n volatile-oleosum_a and_o not_o its_o resinous_a part_n as_o wedelcus_fw-la and_o other_o affirm_v 1._o because_o when_o the_o rosin_n and_o volatile_a salt_n be_v separate_v that_o sparkle_a follow_v the_o volatile_a part_n and_o not_o the_o rosin_n wherein_o they_o do_v not_o appear_v in_o the_o least_o 2._o because_o i_o find_v that_o they_o be_v the_o part_n that_o be_v most_o apt_a to_o dissolve_v in_o water_n which_o the_o rosin_n be_v not_o 3._o because_o they_o be_v much_o alter_v by_o a_o warm_a and_o moist_a breath_n which_o the_o resinous_a part_n be_v not_o 4._o how_o can_v that_o opium_n be_v the_o best_a as_o it_o be_v find_v to_o be_v that_o have_v most_o of_o they_o if_o it_o be_v the_o rosin_n which_o be_v the_o worst_a part_n of_o opium_n but_o it_o be_v high_o consonant_a to_o experience_n that_o they_o shall_v be_v the_o volatile_a or_o
best_a part_n of_o opium_n which_o be_v so_o much_o the_o better_a the_o more_o it_o abound_v with_o they_o 9_o if_o it_o yield_v any_o other_o tincture_n than_o red_a it_o be_v not_o right_a and_o the_o dull_a or_o pale_a the_o red_a be_v the_o worse_a or_o weak_a it_o be_v 10._o the_o best_a be_v heavy_a in_o proportion_n to_o its_o bulk_n which_o you_o may_v soon_o experiment_n thus_o weigh_v a_o ounce_n of_o each_o in_o the_o air_n then_o weigh_v they_o just_a as_o they_o be_v in_o the_o brass_n scales_n in_o water_n and_o the_o heavy_a will_n outweigh_v the_o other_o in_o water_n for_o the_o heavy_a any_o thing_n be_v the_o less_o water_n take_v from_o its_o weight_n in_o proportion_n to_o its_o bulk_n this_o be_v a_o infallible_a and_o most_o ready_a way_n to_o know_v the_o weight_n of_o any_o thing_n in_o proportion_n to_o its_o bulk_n note_v that_o my_o discourse_n be_v most_o particular_o concern_v the_o best_a sort_n of_o crude_a turkey_n opium_n that_o be_v the_o best_a that_o we_o have_v in_o common_a use_n and_o that_o its_o effect_n and_o not_o those_o of_o any_o preparation_n thereof_o be_v set_v down_o in_o the_o follow_a chapter_n chap_n iii_o the_o effect_n of_o opium_n use_v external_o opium_n use_v external_o have_v two_o sort_n of_o effect_n upon_o a_o humane_a body_n 1._o as_o a_o opiate_n to_o cause_n sleep_n take_v away_o pain_n etc._n etc._n 2._o as_o a_o alterative_a of_o the_o part_n it_o be_v apply_v to_o i._o as_o a_o opiate_n it_o be_v of_o very_o uncertain_a and_o uneven_a effect_n when_o apply_v external_o for_o sometime_o it_o cause_v sleep_n take_v away_o pain_n but_o it_o often_o fail_v therefore_o it_o be_v general_o much_o better_a safe_a more_o certain_a and_o effectual_a to_o use_v it_o internal_o i_o do_v scarce_o know_v the_o case_n wherein_o it_o be_v better_a to_o use_v it_o external_o than_o internal_o unless_o it_o be_v to_o smell_v to_o in_o some_o case_n but_o of_o these_o thing_n more_o particular_o when_o we_o come_v to_o the_o use_v of_o opium_n in_o cure_v prevent_v or_o paliate_a disease_n for_o here_o we_o only_o lie_v down_o effect_n in_o order_n to_o a_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n to_o which_o its_o internal_a effect_n will_v main_o contribute_v however_o it_o may_v be_v very_o useful_a to_o that_o end_n to_o lay_v down_o its_o alterative_a effect_n for_o thereby_o we_o shall_v in_o good_a measure_n know_v the_o prin_fw-mi ciple_n by_o which_o it_o operate_v ii_o it_o be_v external_a effect_n as_o a_o alterative_a be_v these_o viz._n 1._o it_o incides_fw-la resolve_n and_o discuss_n 2._o it_o relax_n and_o mollify_v 3._o it_o maturate_v and_o suppurate_v 4._o it_o exulcerate_v or_o cause_n blister_n if_o it_o be_v very_o strong_a and_o apply_v to_o person_n of_o a_o fine_a texture_n where_o the_o skin_n be_v tender_a but_o this_o effect_n belong_v more_o proper_o to_o the_o maslack_n or_o true_a 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o drop_n from_o the_o incision_n make_v in_o the_o head_n of_o the_o poppy_n especial_o the_o theban_a which_o afford_v a_o very_a powerful_a juice_n hence_o you_o may_v observe_v that_o the_o more_o it_o exulcerates_n or_o blister_n the_o better_a be_v the_o opium_n &_o vice_fw-la versâ_fw-la 5._o it_o be_v a_o psilotherick_n for_o it_o prevent_v hair_n to_o grow_v and_o cause_v the_o shed_v thereof_o 6._o it_o be_v hurtful_a to_o the_o eye_n and_o ear_n 7._o it_o excite_v itch_n apply_v in_o a_o moderate_a manner_n to_o the_o skin_n 8._o it_o excite_v venery_n apply_v to_o the_o perinaeum_n chap._n iu._n the_o effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o the_o moderate_a do_v in_o ordinary_a use_n to_o produce_v the_o follow_a effect_n be_v from_o one_o to_o three_o grain_n more_o or_o less_o according_a to_o the_o circumstance_n condition_n case_n constitution_n age_n &c_n &c_n of_o the_o person_n who_o take_v it_o 2._o it_o operate_v general_o in_o a_o short_a time_n after_o it_o be_v in_o the_o stomach_n that_o be_v in_o about_o half_a a_o hour_n more_o or_o less_o if_o take_v in_o a_o liquid_a form_n and_o in_o about_o a_o hour_n more_o or_o less_o if_o in_o a_o solid_a form_n drink_v a_o draught_n of_o water_n or_o some_o liquor_n after_o it_o otherwise_o it_o may_v be_v sometime_o near_o a_o hour_n and_o a_o half_a before_o it_o have_v its_o full_a effect_n but_o the_o time_n of_o its_o operation_n have_v a_o considerable_a latitude_n according_a to_o the_o disposition_n of_o the_o stomach_n and_o other_o circumstance_n as_o the_o vehicle_n it_o be_v take_v in_o etc._n etc._n the_o constant_a effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o diffuse_v itself_o in_o a_o kind_n of_o indefinite_a manner_n seizing_z one_o not_o unlike_o the_o gentle_a sweet_a deliquium_fw-la that_o we_o find_v upon_o our_o entrance_n into_o a_o most_o agreeable_a slumber_n which_o upon_o yield_v to_o it_o general_o end_v in_o sleep_n but_o if_o the_o person_n keep_v himself_o in_o action_n discourse_n or_o business_n it_o seem_v especial_o when_o give_v in_o a_o mornning_a after_o a_o moderate_a rest_n at_o night_n like_o a_o most_o delicious_a and_o extraordinary_a refreshment_n of_o the_o spirit_n upon_o very_o good_a news_n or_o any_o other_o great_a cause_n of_o joy_n as_o the_o sight_n of_o a_o dear_o belove_a person_n etc._n etc._n thought_n to_o have_v be_v lose_v at_o sea_n or_o the_o like_a cause_v such_o a_o pleasant_a ovation_n of_o the_o spirit_n serenity_n etc._n etc._n as_o we_o find_v after_o a_o competent_a measure_n of_o generous_a wine_n ad_fw-la hilaritatem_fw-la as_o man_n use_v to_o say_v it_o be_v indeed_o so_o unexpressible_o fine_a and_o sweet_a a_o pleasure_n that_o it_o be_v very_o difficult_a for_o i_o to_o describe_v or_o any_o to_o conceive_v it_o but_o such_o as_o actual_o feel_v it_o for_o it_o be_v as_o if_o a_o good_a genius_n possess_v or_o inform_v a_o man_n therefore_o people_n do_v common_o call_v it_o a_o heavenly_a condition_n as_o if_o no_o worldly_a pleasure_n be_v to_o be_v compare_v with_o it_o helmontianus_fw-la will_v doubtless_o express_v it_o by_o the_o archaeus_n in_o his_o very_a best_a humour_n it_o have_v be_v compare_v not_o without_o good_a cause_n to_o a_o permanent_a gentle_a degree_n of_o that_o pleasure_n which_o modesty_n forbid_v the_o name_n of_o and_o it_o be_v well_o worth_a a_o remark_n that_o both_o be_v pleasure_n of_o the_o same_o sense_n viz._n that_o of_o feel_v for_o it_o can_v be_v a_o pleasure_n of_o any_o other_o sense_n since_o it_o be_v internal_a 2._o it_o cause_v a_o brisk_a gay_a and_o good_a humour_n nor_o do_v i_o doubt_v but_o it_o have_v this_o effect_n upon_o sleep_a person_n as_o far_o as_o their_o condition_n be_v capable_a of_o observe_v it_o for_o you_o shall_v have_v they_o often_o tell_v of_o pleasant_a dream_n after_o it_o when_o they_o remember_v they_o and_o speak_v of_o any_o see_v bauchin_n and_o the_o author_n mention_v below_o under_o the_o four_o effect_n of_o opium_n 3._o it_o cause_v promptitude_n serenity_n alacrity_n and_o expediteness_n in_o dispatch_v and_o manage_n of_o business_n to_o which_o end_n and_o that_o of_o a_o good_a and_o gay_a humour_n which_o be_v near_o of_o kind_n it_o be_v common_o take_v in_o the_o morning_n in_o the_o eastern_a country_n with_o most_o certain_a effect_n the_o truth_n of_o which_o wedelius_n be_v force_v to_o confess_v though_o quite_o contrary_a to_o his_o hypothesis_n of_o opium_n fix_v and_o coagulate_v the_o spirit_n give_v a_o instance_n of_o a_o certain_a serene_a person_n who_o when_o she_o have_v any_o affair_n of_o great_a moment_n to_o dispatch_v do_v beforehand_o take_v opium_n with_o great_a advantage_n for_o she_o thereby_o find_v herself_o every_o way_n better_o dispose_v for_o business_n and_o more_o enable_v to_o bear_v the_o fatigue_n thereof_o which_o be_v the_o substance_n of_o what_o he_o write_v in_o latin_n many_o other_o author_n confirm_v the_o truth_n of_o these_o effect_n but_o above_o all_o the_o constant_a experience_n of_o the_o eastern_a nation_n put_v it_o out_o of_o all_o doubt_n 4._o it_o cause_v assurance_n ovation_n of_o the_o spirit_n courage_n contempt_n of_o danger_n and_o magnanimity_n much_o after_o the_o manner_n that_o generous_a wine_n do_v instead_o of_o which_o the_o turk_n etc._n etc._n use_v opium_n before_o engagement_n desperate_a attack_n etc._n etc._n as_o be_v most_o notorious_a to_o make_v they_o courageous_a which_o it_o certain_o do_v for_o your_o satisfaction_n as_o to_o this_o and_o other_o effect_n of_o opium_n not_o so_o common_o observe_v
with_o we_o for_o reason_n give_v in_o chap._n viii_o see_v bellonius_fw-la l._n 3._o c._n 15._o p._n 179._o erastus_n disp._n de_fw-fr sapor_n p._n 6â—_n georg._n andreae_n itenerar_n ind._n l._n 2._o c._n 9_o p._n 12._o camerar_fw-it oper._n subcis_n l._n 1._o c._n 93._o p._n 437._o erastus_n disp._n de_fw-fr narcot_n oberndorf_n historian_n also_o add_v that_o when_o the_o great_a turk_n make_v a_o considerable_a war_n the_o soldier_n buy_v up_o all_o or_o most_o of_o the_o opium_n which_o may_v be_v worth_a a_o merchant_n observation_n for_o it_o thereupon_o grow_v dear_a and_o be_v much_o cheap_a in_o time_n of_o peace_n 5._o it_o prevent_v and_o take_v away_o grief_n fear_v anxiety_n peevishness_n fretfulness_n etc._n etc._n these_o be_v necessary_a consequence_n of_o the_o former_a effect_n 6._o it_o cause_v euphory_n or_o easy_a undergo_n of_o all_o labour_n journey_n etc._n etc._n and_o that_o far_o beyond_o all_o wine_n and_o hot_a cordial_n or_o spirit_n therefore_o it_o be_v very_o much_o use_v in_o turkey_n and_o the_o eastern_a country_n in_o laborious_a undertake_n great_a journey_n etc._n etc._n which_o man_n perform_v by_o the_o help_n of_o opium_n after_o a_o prodigious_a and_o almost_o incredible_a manner_n but_o the_o matter_n of_o fact_n be_v so_o common_a and_o usual_a that_o there_o be_v no_o place_n of_o doubt_n beside_o that_o some_o who_o try_v it_o among_o we_o have_v find_v it_o so_o 7._o it_o lull_v soothe_v and_o as_o it_o be_v charm_v the_o mind_n with_o satisfaction_n acquiescence_n contentation_n equanimity_n etc._n etc._n how_o shall_v it_o fail_v to_o cause_v these_o effect_n since_o it_o cause_v all_o the_o former_a gay_a pleasant_a and_o brave_a humour_n dr._n willis_n and_o other_o have_v no_o true_a experience_n or_o knowledge_n of_o opium_n imagine_v that_o it_o cause_v courage_n bravery_n equanimity_n etc._n etc._n by_o stupify_a the_o sense_n brain_n etc._n etc._n make_v people_n inadvertent_n dull_a and_o inapprehensive_a which_o be_v a_o great_a mistake_n and_o a_o groundless_a conceit_n for_o it_o be_v a_o most_o certain_a truth_n which_o million_o can_v affirm_v that_o it_o produce_v those_o effect_n by_o a_o ovation_n and_o pleasure_n of_o the_o sensitive_a soul_n and_o spirit_n as_o generous_a wine_n do_v before_o man_n be_v suddle_v or_o overcome_v with_o it_o how_o else_o can_v they_o at_o the_o same_o time_n be_v more_o serene_a and_o apt_a for_o the_o management_n of_o any_o business_n and_o neat_a dispatch_n of_o affair_n as_o it_o be_v most_o certain_a they_o be_v these_o fundamental_a mistake_v about_o opium_n have_v be_v as_o you_o will_v find_v hereafter_o one_o great_a cause_n why_o its_o operation_n have_v puzzle_v and_o quite_o baffle_v all_o enquirer_n 8._o it_o quiet_v allay_v and_o compose_v all_o perturbation_n and_o commotion_n of_o the_o spirit_n or_o sensitive_a soul_n blood_n humour_n etc._n etc._n as_o in_o hysterical_a case_n diary_n fever_n that_o proceed_v from_o passion_n as_o anger_n grief_n terror_n etc._n etc._n from_o violent_a motion_n labour_n heat_v journey_n convulsion_n etc._n etc._n or_o from_o pain_n and_o stop_v bleedings_a that_o proceed_v from_o such_o commotion_n 9_o it_o cause_v a_o relaxation_n of_o all_o the_o sensible_a part_n of_o the_o body_n as_o the_o membranous_a and_o nervous_a this_o be_v notorious_a by_o its_o effect_n as_o cause_v perspiration_n sweat_v relaxation_n of_o sphincter_n vilatation_n of_o the_o pupil_n of_o the_o eye_n relaxation_n of_o the_o cornea_n and_o all_o other_o effect_n of_o relaxation_n as_o you_o will_v find_v more_o particular_o hereafter_o 10._o it_o cause_v indolence_n or_o exemption_n from_o pain_n as_o all_o know_v and_o allow_v and_o that_o when_o sleep_n do_v not_o intervene_v 11._o it_o stop_v moderate_v cure_n or_o paliate_v all_o flux_n except_v those_o by_o the_o pore_n or_o such_o as_o depend_v as_o that_o do_v upon_o relaxation_n as_o when_o sphincter_n be_v weak_a or_o paralytical_a but_o these_o last_o be_v unnatural_a accident_n 12._o it_o mighty_o promote_v insensible_a perspiration_n 13._o it_o prevent_v shivering_n in_o ague-fits_a and_o suchlike_a case_n if_o give_v in_o due_a time_n and_o quantity_n which_o shall_v be_v show_v in_o the_o curative_fw-it part._n 14._o it_o prevent_v and_o cure_v cold_n 15._o it_o cause_v a_o large_a and_o slow_a pulse_n suppose_v no_o accidental_a cause_n to_o the_o contrary_n 16._o it_o cause_v dryness_n in_o the_o mouth_n 17._o it_o have_v most_o effect_n in_o warm_a and_o moist_a wether_n 18._o it_o have_v more_o effect_n upon_o lax_n and_o fine_a textured_a person_n as_o woman_n child_n etc._n etc._n therefore_o woman_n seldom_o use_v it_o in_o turkey_n and_o the_o other_o eastern_a country_n where_o it_o be_v common_o use_v by_o the_o men._n 19_o it_o cause_v a_o efflorescence_n of_o the_o skin_n bar_v accident_n of_o cold_a etc._n etc._n 20._o it_o be_v observe_v by_o all_o that_o it_o main_o affect_v the_o genus_fw-la nervosum_fw-la and_o animal_n spirit_n and_o not_o the_o blood_n and_o humour_n 21._o it_o increase_v seed_n in_o some_o measure_n 22._o it_o cause_v a_o great_a promptitude_n to_o venery_n erection_n etc._n etc._n especial_o if_o the_o do_v be_v large_a than_o ordinary_a which_o i_o will_v have_v man_n believe_v without_o experiment_v it_o not_o that_o i_o fear_v to_o be_v confute_v but_o lest_o any_o shall_v injure_v themselves_o by_o too_o great_a a_o do_v this_o be_v one_o great_a cause_n if_o not_o the_o chief_a why_o the_o infidel_n of_o turkey_n and_o the_o eastern_a nation_n especial_o where_o polygamy_n be_v allow_v as_o among_o the_o turk_n etc._n etc._n use_v opium_n so_o much_o it_o never_o â—ailing_v to_o produce_v this_o effect_n in_o hale_v and_o healthy_a people_n if_o the_o do_v be_v sufficient_a as_o be_v too_o notorious_a in_o all_o or_o most_o country_n from_o greece_n to_o japan_n inclusive_o who_o use_v opium_n for_o that_o end_n but_o as_o to_o the_o truth_n of_o this_o effect_n of_o opium_n not_o only_o author_n and_o all_o the_o people_n of_o those_o eastern_a nation_n but_o several_a merchant_n factor_n and_o traveller_n now_o live_v in_o london_n can_v attest_v that_o it_o be_v use_v for_o that_o purpose_n in_o those_o country_n with_o effect_n yea_o some_o in_o our_o own_o nation_n that_o use_v opium_n in_o large_a dose_n can_v attest_v the_o same_o upon_o experience_n in_o their_o own_o body_n those_o who_o desire_v to_o be_v satisfy_v may_v also_o read_v joh._n jacob_n saar_n his_o itinerar_n ind._n p._n 11._o olearius_n â—tinerar_n persio_fw-la l._n 5._o c._n 15._o &_o 18._o b._n d._n d._n sack_n tom._n 11._o epher_n german_n obs._n 69._o p._n 126._o bauchin_n p._n 450._o cardanus_n scaliger_n nich._n monordei_n fogâ—lius_fw-la de_fw-la turcarum_fw-la nepenthe_n bellonius_fw-la and_o other_o who_o word_n i_o do_v not_o repeat_v partly_o for_o modesty_n partly_o for_o brevity_n sake_n it_o do_v i_o confess_v look_v like_o a_o riddle_n that_o a_o most_o relax_a and_o stupify_a medicament_n which_o take_v away_o much_o of_o the_o sense_n of_o feel_v and_o consequent_o irritation_n to_o venery_n as_o one_o will_v think_v shall_v notwithstanding_o irritate_fw-la thereunto_o cause_n erection_n etc._n etc._n however_o it_o be_v most_o certain_a though_o a_o seem_a contradiction_n of_o which_o sort_n you_o have_v many_o more_o among_o the_o effect_n of_o opium_n usual_a and_o frequent_a though_o not_o constant_a effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o sleep_v which_o be_v so_o far_o from_o be_v a_o constant_a effect_n of_o opium_n that_o it_o will_v in_o i_o and_o many_o other_o person_n prevent_v sleep_v even_o when_o otherwise_o incline_v to_o it_o 2._o pleasant_n dream_n 3._o stop_v of_o vomit_n 4._o still_v the_o hiccough_n 5._o take_v off_o convulsion_n and_o contraction_n 6._o cause_v meat_n to_o stay_v long_o at_o stomach_n 7._o moderation_n and_o prevention_n of_o hunger_n 8._o sweat_n 9_o the_o flow_v of_o the_o menses_fw-la though_o not_o observe_v by_o vulgar_a physician_n 10._o the_o flow_v of_o the_o lochia_n which_o be_v as_o little_o observe_v 11._o void_v of_o the_o stone_n 12._o delivery_n of_o woman_n 13._o deadness_n of_o the_o eye_n as_o you_o see_v in_o drunkenness_n 14._o dilatation_n of_o the_o pupil_n 15._o growth_n of_o the_o breast_n penis_n and_o increase_v of_o milk_n 16._o veneral_a dream_n 17._o nocturnal_a pollution_n 18._o itch_n in_o the_o skin_n 19_o much_o urine_n 20._o nausea_n 21._o swimmings_n in_o the_o head_n 22._o watch_v 23._o a_o kind_n of_o dubious_a state_n between_o sleep_v and_o wake_v 24._o it_o stop_v hemorrhage_n in_o many_o case_n many_o more_o instance_n of_o this_o kind_n may_v be_v give_v of_o its_o frequent_a and_o usual_a effect_n in_o disease_n but_o it_o will_v be_v endless_a and_o needless_a since_o we_o have_v mention_v the_o prime_n general_n and_o fundamental_a effect_n upon_o which_o
all_o such_o do_v depend_v and_o that_o the_o particular_a enumeration_n of_o its_o effect_n in_o disease_n belong_v to_o its_o curative_fw-it and_o paliative_fw-it virtue_n which_o will_v be_v handle_v hereafter_o the_o rare_a effect_n of_o opium_n take_v in_o a_o moderate_a do_v 1._o temporary_a palsy_n as_o of_o the_o bladder_n and_o sometime_o of_o other_o part_n though_o very_o rare_o 2._o falter_v of_o the_o tongue_n 3._o looseness_n of_o the_o low_a jaw_n as_o in_o the_o drowsy_a drunkard_n etc._n etc._n 4._o prevention_n of_o sweat_n in_o such_o as_o sweat_v too_o much_o for_o want_v of_o perspiration_n 5._o abortion_n 6._o prevention_n of_o abortion_n in_o some_o case_n 7._o intumescence_n of_o the_o li_n 8._o cure_v of_o the_o dropsy_n of_o which_o dr._n willis_n give_v a_o instance_n 9_o cure_v of_o stupor_n of_o some_o sort_n as_o those_o from_o cold_n etc._n etc._n 10._o anxiety_n and_o distress_n 11._o vomit_n and_o hiccough_n 12._o convulsion_n 13._o syncopes_fw-la leipothimy_n and_o faint_n 14._o death_n though_o very_o rare_o and_o that_o in_o very_o weak_a people_n 15._o purge_v 16._o raise_v and_o revive_v some_o person_n that_o be_v just_a expire_a 17._o a_o long_a stay_n thereof_o at_o stomach_n sometime_o 18._o stoppage_n of_o urine_n 19_o it_o sometime_o prove_v dangerous_a after_o hemorrhage_n and_o large_a evacuation_n 1._o note_v that_o the_o first_o class_n of_o effect_n be_v the_o most_o constant_a be_v the_o most_o proper_a genuine_a and_o principal_a effect_n upon_o which_o all_o other_o effect_n depend_v unless_o they_o be_v accidental_a it_o must_v therefore_o be_v that_o these_o shall_v best_a guide_v we_o in_o the_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n 2._o note_v that_o the_o second_o class_n though_o not_o so_o constant_a be_v natural_a effect_n of_o opium_n and_o will_v be_v also_o good_a guide_n for_o the_o same_o purpose_n 3._o note_v that_o there_o be_v but_o little_a notice_n to_o be_v take_v of_o the_o rare_a effect_n for_o that_o purpose_n because_o most_o accidental_a the_o effect_n of_o the_o go_v off_o or_o declination_n of_o the_o operation_n of_o opium_n take_v internal_o in_o a_o moderate_a do_v 1._o a_o general_a return_n of_o all_o the_o disease_n and_o disaster_n that_o opium_n paliate_v during_o its_o operation_n unless_o it_o happen_v that_o some_o be_v cure_v thereby_o which_o iâ—_n they_o be_v be_v general_o by_o the_o benefit_n of_o sweat_n or_o insensible_a perspiration_n as_o cold_n pain_n from_o wind_n or_o humour_n that_o shall_v have_v pass_v by_o the_o pore_n as_o in_o cough_n toothache_n etc._n etc._n from_o construction_n of_o the_o pore_n or_o by_o compose_v the_o fury_n of_o the_o spirit_n or_o blood_n which_o it_o very_o often_o yea_o general_o cure_v with_o one_o single_a do_v but_o of_o these_o thing_n more_o in_o the_o curative_fw-it part._n 2._o sweat_v though_o not_o constant_o 3._o frequent_v make_v of_o water_n sometime_o 4._o a_o looseness_n sometime_o even_o when_o there_o be_v none_o before_o the_o give_v of_o the_o opium_n 5._o disease_n seem_v worse_a than_o before_o the_o take_n of_o it_o 6._o a_o melancholy_a and_o sad_a depression_n of_o spirit_n 7._o a_o narrow_a pulse_n 8._o itch_a of_o the_o skin_n chap._n v._o the_o effect_n of_o opium_n take_v in_o a_o excessive_a quantity_n 1._o a_o heat_n at_o stomach_n 2._o a_o sense_n of_o weight_n at_o stomach_n sometime_o 3._o gaity_n of_o humour_n at_o first_o aâ—_n after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 4._o sardonick_a laughter_n afterward_o as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 5._o laxity_n and_o debility_n of_o all_o part_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 6._o alienation_n of_o the_o mind_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 7._o loss_n of_o memory_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 8._o darkness_n of_o the_o eye_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 9_o laxity_n of_o the_o cornea_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 10._o appearance_n of_o divers_a colour_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 11._o deadness_n of_o the_o eye_n to_o the_o view_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 12._o falter_v of_o the_o tongue_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 13._o a_o sopor_fw-la as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 14._o a_o slow_a and_o wide_a pulse_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 15._o a_o high_a colour_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 16._o looseness_n of_o the_o jaw_n and_o li_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 17._o intumescence_n of_o the_o li_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 18._o difficulty_n of_o breathe_v as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 19_o fury_n and_o madness_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 20._o venereal_a fury_n 21._o priapism_n 22._o violent_a itch_n 23._o nausea_n 24._o swimmings_n in_o the_o head_n 25._o vertigo_n 26._o vomit_n 27._o hiccough_n 28._o a_o turbulent_a pulse_n 29._o convulsion_n and_o cold_a sweat_v 30._o faint_n and_o leipothymy_n 31._o cold_a breath_n 32._o death_n such_o as_o escape_v it_o general_o have_v 33._o plentiful_a purge_v 34._o sweat_v that_o smell_n of_o the_o opium_n 35._o violent_a itch_n in_o the_o skin_n 1._o note_v that_o all_o these_o effect_n do_v not_o happen_v to_o all_o but_o some_o to_o one_o and_o some_o to_o other_o 2._o that_o these_o effect_n be_v great_a or_o less_o according_a to_o the_o do_v constitution_n of_o the_o person_n and_o other_o circumstance_n 3._o that_o they_o be_v most_o endanger_v thereby_o that_o have_v a_o lax_n and_o fine_a texture_n and_o a_o weak_a digestion_n 4._o that_o a_o looseness_n upon_o it_o be_v a_o good_a sign_n 5._o that_o it_o affect_v some_o by_o make_v they_o furious_a as_o wine_n do_v and_o other_o stupid_a general_o the_o furious_a be_v most_o safe_a from_o danger_n of_o death_n but_o of_o these_o thing_n more_o hereafter_o by_o god_n help_n chap._n vi_o the_o effect_n of_o a_o long_a and_o lavish_a use_n of_o crude_a opium_n 1._o relaxation_n and_o weakness_n of_o all_o part_n 2._o inhability_n or_o listlesness_n to_o do_v any_o thing_n except_o it_o be_v while_o the_o opium_n operate_v 3._o inhability_n or_o listlesness_n to_o get_v up_o in_o the_o morning_n 4._o a_o dull_a moapish_a and_o heavy_a disposition_n as_o in_o old_a drunkard_n except_o it_o be_v during_o the_o operation_n of_o opium_n 5._o diminution_n of_o appetite_n as_o be_v observable_a in_o old_a drunkard_n 6._o weakness_n of_o digestion_n as_o be_v observable_a in_o old_a drunkard_n 7._o dropsy_n as_o be_v observable_a in_o old_a drunkard_n 8._o decay_n of_o part_n as_o be_v observable_a in_o old_a drunkard_n 9_o weakness_n of_o memory_n as_o be_v observable_a in_o old_a drunkard_n 10._o stoop_v in_o the_o back_n as_o be_v observable_a in_o old_a drunkard_n 11._o early_o decrepiteness_n as_o be_v observable_a in_o old_a drunkard_n 12._o shortness_n of_o life_n as_o be_v observable_a in_o old_a drunkard_n 13._o acrimony_n of_o blood_n 14._o inclination_n to_o venery_n 15._o frequent_a inclination_n to_o make_v water_n 16._o priapism_n and_o frequent_a erection_n 17._o nocturnal_a pollution_n the_o effect_n of_o sudden_a leave_v off_o the_o use_n of_o opium_n after_o a_o long_a and_o lavish_a use_v thereof_o 1._o great_a and_o even_o intolerable_a distress_n anxiety_n and_o depression_n of_o spirit_n which_o in_o few_o day_n common_o end_v in_o a_o most_o miserable_a death_n attend_v with_o strange_a agony_n unless_o man_n return_v to_o the_o use_v of_o opium_n which_o soon_o raise_v they_o again_o and_o certain_o restore_v they_o if_o it_o have_v time_n to_o operate_v before_o they_o die_v which_o it_o soon_o do_v in_o a_o liquid_a form_n or_o if_o they_o have_v not_o opium_n or_o will_v not_o take_v it_o they_o must_v use_v wine_n very_o plentiful_o and_o often_o as_o a_o substitute_n to_o the_o opium_n though_o it_o do_v not_o perform_v half_a as_o well_o as_o opium_n 2._o a_o return_n of_o all_o disease_n pain_n and_o disaster_n that_o be_v palliate_v by_o the_o take_n of_o opium_n 3._o dangerous_a looseness_n 4._o death_n follow_v the_o leave_v it_o off_o after_o
a_o very_o long_o and_o lavish_a use_n thereof_o the_o inconvenience_n of_o leave_v off_o the_o use_n of_o opium_n do_v bear_v a_o certain_a proportion_n to_o the_o time_n and_o quantity_n that_o it_o have_v be_v use_v in_o 1._o note_v that_o the_o turk_n do_v drink_v some_o water_n always_o after_o the_o take_n of_o opium_n as_o be_v the_o best_a menstruum_fw-la to_o dissolve_v it_o 2._o note_v that_o it_o be_v usual_a with_o they_o to_o take_v a_o drachm_n in_o the_o morning_n and_o so_o much_o in_o the_o afternoon_n and_o so_o may_v we_o as_o well_o as_o they_o if_o use_v to_o it_o and_o it_o be_v a_o very_a silly_a say_n that_o you_o will_v find_v in_o author_n that_o they_o be_v better_a able_a to_o bear_v it_o because_o of_o the_o climate_n etc._n etc._n whereas_o the_o more_o northern_a person_n be_v better_a able_a to_o take_v it_o than_o the_o southern_a as_o will_v hereafter_o appear_v most_o plain_o i_o be_o tell_v of_o one_o near_o banbury_n that_o take_v two_o ounce_n a_o day_n 3._o note_v that_o among_o the_o effect_n of_o opium_n may_v be_v observe_v many_o seem_a contradiction_n yet_o be_v there_o nothing_o more_o certain_a than_o the_o several_a different_a matter_n of_o fact_n which_o no_o doubt_n have_v be_v a_o great_a cause_n to_o puzzle_v the_o world_n about_o it_o and_o to_o run_v man_n into_o strange_a absurdity_n concern_v its_o operation_n and_o all_o to_o deviate_v so_o far_o from_o the_o truth_n that_o nothing_o in_o nature_n can_v be_v far_o unless_o you_o will_v say_v that_o heat_n cool_v or_o what_o please_v the_o sensitive_a soul_n be_v at_o the_o same_o time_n abhor_v by_o it_o now_o because_o these_o seem_a contradiction_n in_o the_o effect_n of_o opium_n be_v the_o great_a rub_n to_o be_v meet_v with_o and_o that_o the_o reader_n may_v take_v the_o better_a estimate_n of_o the_o undertake_n and_o my_o explication_n of_o its_o effect_n when_o i_o come_v to_o it_o i_o shall_v not_o fear_v to_o enumerate_v they_o distinct_o though_o they_o will_v make_v the_o strange_a catalogue_n of_o riddle_n that_o ever_o be_v see_v trust_v in_o he_o that_o create_v this_o wonderful_a medicament_n that_o he_o will_v enable_v i_o to_o explain_v all_o its_o effect_n the_o seem_a contradiction_n in_o the_o effect_n of_o opium_n 1._o it_o cause_v sleep_v and_o watch_v 2._o it_o cause_n and_o prevent_v sweat_n 3._o it_o relax_n and_o stop_v looseness_n 4._o it_o stop_v flux_n and_o cause_n that_o of_o sweat_n etc._n etc._n 5._o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v by_o that_o sense_n to_o venery_n 6._o it_o cause_v stupidity_n and_o promptitude_n in_o business_n cloudiness_n and_o serenity_n of_o mind_n 7._o it_o excite_v the_o spirit_n and_o quiet_v they_o 8._o it_o be_v very_o hot_a yet_o cool_v in_o fever_n 9_o it_o be_v hot_a and_o bitter_a yet_o lessen_v appetite_n even_o in_o cold_a stomach_n 10._o it_o stop_v and_o promote_v urine_n 11._o it_o relax_n and_o weaken_v yet_o enable_v we_o to_o undergo_v labour_n journey_n etc._n etc._n 12._o it_o cause_n and_o prevent_v abortion_n 13._o it_o stop_v vomit_v above_o all_o thing_n yet_o cause_n most_o violent_a tedious_a and_o dangerous_a vomit_n 14._o it_o stop_v purge_v in_o a_o most_o eminent_a manner_n yet_o sometime_o cause_v it_o 15._o it_o be_v very_o acrimonious_a yet_o as_o all_o say_v obtund_v acrimony_n however_o it_o allay_v pain_n proceed_v from_o acrimony_n 16._o it_o cause_v a_o furious_a madness_n yet_o compose_v the_o spirit_n above_o all_o thing_n 17._o it_o cause_v 〈◊〉_d yet_o sometime_o cure_v they_o as_o willis_n say_v 18._o it_o cause_v palsy_n yet_o have_v i_o know_v it_o to_o cure_v a_o palsy_n 19_o it_o cause_v dryness_n in_o the_o mouth_n yet_o take_v off_o thirst_n in_o fever_n 20._o it_o cure_v and_o cause_v a_o hiccough_n 21._o it_o stanche_n blood_n yet_o cause_v the_o blood_n to_o come_v outward_a as_o appear_v by_o the_o efflorescence_n or_o redness_n of_o the_o skin_n that_o it_o cause_n yet_o move_v the_o menses_fw-la and_o lochia_n 22._o we_o have_v many_o instance_n of_o it_o promote_a and_o hinder_v critical_a motion_n 23._o it_o raise_v very_o weak_a people_n when_o nothing_o beside_o will_v do_v it_o yet_o it_o kill_v other_o weak_a people_n 24._o it_o cause_n and_o cure_n convulsion_n 25._o it_o cause_v relaxation_n and_o contraction_n of_o the_o same_o part_n 26._o it_o relax_n yet_o cause_v rigidity_n tension_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n thus_o have_v i_o fair_o and_o faithful_o lay_v the_o whole_a onus_fw-la of_o the_o operation_n effect_n and_o contradictory_n phenomena_n of_o opium_n upon_o my_o shoulder_n however_o i_o come_v off_o and_o clear_v myself_o of_o the_o intricacy_n maze_n and_o cross_a effect_n thereof_o by_o explain_v they_o which_o none_o upon_o the_o view_n thereof_o will_v think_v possible_a and_o none_o before_o i_o dare_v as_o much_o as_o enumerate_v for_o that_o end_n chap._n vii_o the_o author_n contrive_v a_o compendious_a way_n of_o examine_v all_o opinion_n concern_v the_o operation_n of_o opium_n have_v without_o any_o sly_a or_o sordid_a evasion_n or_o considerable_a omission_n which_o have_v be_v the_o perfidious_a course_n of_o author_n in_o this_o case_n full_o and_o true_o enumerate_v the_o sensible_a and_o certain_a effect_n of_o opium_n in_o humane_a body_n and_o thereby_o empanneled_a a_o just_a jury_n for_o the_o trial_n of_o hypothesise_n which_o must_v be_v judge_v by_o the_o effect_n or_o phenomena_n of_o opium_n i_o will_v now_o proceed_v to_o their_o examination_n but_o because_o it_o will_v be_v endless_a to_o take_v every_o one_o particular_o into_o consideration_n i_o will_v use_v their_o stratagem_n who_o blow_v up_o foundation_n to_o save_v the_o tedious_a peck_v at_o all_o the_o part_n of_o the_o superstructure_n which_o in_o this_o case_n will_v require_v a_o age_n and_o take_v up_o all_o my_o time_n in_o demolish_n they_o which_o may_v be_v better_o employ_v in_o erect_v something_o that_o may_v be_v useful_a i_o have_v consider_v and_o find_v that_o the_o foundation_n in_o which_o all_o author_n both_o ancient_a and_o modern_a agree_v and_o whereupon_o they_o have_v hitherto_o endeavour_v to_o build_v look_v upon_o it_o as_o firm_a and_o warrantable_a in_o all_o age_n be_v this_o viz._n that_o opium_n operate_v by_o diminish_v or_o disable_n the_o spirit_n mean_v the_o animal_n spirit_n the_o ancient_n affirm_v that_o it_o do_v so_o by_o a_o extreme_a cold_a quality_n etc._n etc._n and_o the_o modern_n who_o observe_v it_o to_o act_n while_o it_o be_v at_o stomach_n by_o affect_v the_o brain_n nerve_n animal_n spirit_n etc._n etc._n and_o conclude_v no_o action_n be_v perform_v without_o contact_n infer_v and_o agree_v because_o no_o visible_a passage_n can_v be_v find_v from_o the_o stomach_n to_o the_o head_n that_o it_o must_v of_o absolute_a necessity_n act_v by_o fume_n vapour_n auras_fw-la or_o effluvium_n send_v up_o out_o of_o the_o stomach_n to_o the_o brain_n nerve_n etc._n etc._n so_o that_o all_o the_o remain_a question_n among_o the_o modern_n be_v which_o way_n those_o fume_n or_o vapour_n do_v the_o feat_n all_o allow_v the_o fume_n do_v it_o one_o say_v that_o they_o stuff_v the_o pore_n of_o the_o brain_n and_o so_o hinder_v the_o generation_n of_o animal_n spirit_n a_o second_o that_o they_o constringed_a and_o close_v the_o pore_n together_o thereby_o hinder_v the_o say_a generation_n a_o three_o that_o they_o fix_v and_o coagulate_v the_o animal_n spirit_n as_o wedelius_n and_o other_o a_o four_o that_o they_o cloud_v the_o animal_n spirit_n a_o five_o that_o they_o act_v as_o a_o poison_n as_o willis_n and_o many_o other_o a_o six_o that_o they_o clog_v the_o animal_n spirit_n by_o adhere_v to_o they_o etc._n etc._n not_o know_v nor_o i_o think_v care_v what_o they_o say_v so_o they_o humour_a their_o own_o imagination_n and_o hypothesise_n though_o utter_o incapable_a of_o solve_v the_o effect_n of_o opium_n especial_o be_v most_o constant_a proper_a and_o genuine_a effect_n for_o how_o can_v a_o cold_a quality_n which_o opium_n never_o have_v cause_v a_o gay_a and_o brisk_a humour_n bravery_n magnanimity_n euphory_n in_o labour_n promptitude_n to_o venus_n etc._n etc._n and_o how_o can_v cloud_n of_o vapour_n hinder_v the_o generation_n of_o animal_n spirit_n by_o stuff_v or_o constr_v the_o pore_n of_o the_o brain_n poison_v fix_v coagulate_v clog_a or_o cloud_v the_o animal_n spirit_n cause_v a_o fine_a ovation_n thereof_o a_o gay_a brave_a courageous_a and_o magnanimous_a disposition_n euphory_n promptitude_n to_o venery_n serenity_n expediteness_n in_o management_n etc._n etc._n which_o be_v as_o have_v be_v say_v the_o constant_a and_o proper_a effect_n of_o opium_n nor_o indeed_o be_v any_o of_o those_o author_n so_o foolhardy_a as_o to_o attempt_v it_o
why_o then_o do_v they_o write_v and_o trouble_v the_o world_n to_o peruse_v their_o book_n when_o they_o be_v so_o far_o from_o explain_v the_o property_n of_o opium_n that_o they_o scarce_o ever_o dare_v mention_v they_o nor_o set_v their_o hypothesise_n and_o they_o as_o much_o as_o in_o view_n of_o one_o another_o be_v not_o this_o a_o tacit_n confession_n of_o the_o incompetency_n of_o their_o supposition_n i_o beg_v pardon_n for_o call_v they_o they_o though_o they_o themselves_o do_v for_o i_o can_v offer_v they_o a_o great_a abuse_n than_o lay_v their_o spurious_a and_o lame_a brat_n at_o their_o door_n though_o one_o scarce_o need_v say_v any_o more_o of_o they_o yet_o lest_o i_o be_v think_v presumptuous_a or_o saucy_a for_o so_o much_o as_o offer_v to_o suspect_v the_o general_a foundation_n of_o all_o the_o famous_a author_n that_o ever_o live_v as_o galen_n avicenna_n etc._n etc._n among_o the_o ancient_n etmuller_n willis_n etc._n etc._n among_o the_o modern_n 1._o i_o will_v show_v you_o very_o just_a cause_n to_o suspect_v the_o insufficiency_n of_o the_o general_a foundation_n viz._n that_o opium_n diminish_v or_o disable_v the_o spirit_n 2._o i_o will_v prove_v that_o it_o do_v not_o do_v it_o by_o a_o cold_a quality_n 3._o that_o it_o do_v not_o do_v it_o by_o vapour_n fume_n aura_n or_o any_o such_o way_n 4._o that_o it_o diminish_v or_o disable_v the_o spirit_n by_o no_o mean_n whatsoever_o which_o diminish_v or_o disable_n of_o the_o spirit_n cold_a quality_n and_o fume_n or_o aura_n comprehend_v the_o foundation_n of_o all_o opinion_n concern_v opium_n that_o ever_o i_o read_v or_o hear_v of_o and_o consequent_o if_o those_o two_o fundamental_a opinion_n be_v refute_v all_o the_o superstructure_n that_o have_v be_v in_o this_o case_n must_v fall_v to_o the_o ground_n chap._n viii_o the_o author_n show_v just_a cause_n of_o his_o suspicion_n that_o all_o author_n have_v go_v upon_o a_o wrong_a foundation_n in_o their_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n i_o have_v show_v you_o that_o the_o general_a foundation_n of_o both_o ancient_n and_o modern_a author_n be_v that_o opium_n do_v diminish_v or_o disable_v the_o spirit_n and_o now_o i_o will_v plain_o show_v just_a cause_n of_o my_o suspicion_n of_o its_o insufficiency_n which_o be_v these_o 1._o i_o observe_v that_o all_o learned_a man_n be_v to_o this_o day_n high_o dissatisfy_v as_o to_o the_o cause_n and_o manner_n of_o the_o operation_n of_o opium_n notwithstanding_o all_o that_o have_v be_v write_v concern_v it_o and_o that_o it_o be_v the_o common_a cry_n on_o all_o hand_n that_o none_o have_v illustrate_v the_o operation_n of_o opium_n to_o any_o purpose_n or_o give_v any_o satisfaction_n therein_o and_o therefore_o learned_a physician_n be_v still_o as_o much_o upon_o the_o enquiry_n as_o ever_o they_o be_v it_o be_v much_o more_o civil_a and_o reasonable_a to_o suspect_v the_o foundation_n that_o all_o former_a author_n have_v build_v upon_o than_o a_o general_a failure_n in_o all_o the_o most_o judicious_a master_n builder_n that_o ever_o endeavour_v to_o build_v thereon_o for_o if_o all_o the_o best_a architect_n of_o the_o whole_a world_n fail_v to_o erect_v a_o firm_a superstructure_n upon_o any_o one_o foundation_n what_o can_v we_o think_v but_o that_o the_o foundation_n be_v infirm_a especial_o when_o as_o in_o our_o case_n no_o way_n that_o care_n judgement_n perspicacity_n and_o wit_n can_v invent_v or_o think_v of_o have_v be_v leave_v untried_a to_o build_v thereon_o so_o that_o though_o i_o modest_o call_v it_o a_o cause_n of_o suspicion_n it_o amount_v almost_o if_o not_o altogether_o to_o a_o demonstration_n that_o the_o foundation_n that_o all_o author_n have_v go_v upon_o be_v naught_o will_v not_o any_o consider_a man_n when_o he_o see_v all_o the_o judicious_a architect_n of_o the_o world_n fail_v to_o erect_v a_o firm_a building_n upon_o a_o certain_a foandation_n seek_v for_o another_o therefore_o who_o can_v blame_v i_o if_o i_o do_v and_o not_o blame_v they_o that_o do_v not_o the_o mean_a bricklayer_n or_o carpenter_n that_o shall_v be_v guilty_a of_o such_o stupidity_n as_o to_o attempt_v to_o build_v upon_o such_o a_o foundation_n as_o always_o deceive_v the_o builder_n will_v be_v think_v too_o great_a a_o blockhead_n to_o be_v employ_v in_o building_n 2._o i_o observe_v that_o most_o man_n do_v notwithstanding_o that_o foundation_n be_v agree_v upon_o think_v it_o impossible_a to_o explain_v the_o intricate_a various_a contradictory_n phenomena_n and_o mysterious_a effect_n of_o opium_n sit_v content_v and_o persuade_v that_o it_o operate_v by_o a_o occult_a quality_n whole_o unexplicable_a and_o particular_o reserve_v from_o the_o knowledge_n of_o mankind_n but_o nature_n work_v mechanical_o in_o weight_n measure_n etc._n etc._n therefore_o it_o be_v more_o than_o probable_a that_o it_o be_v only_o their_o be_v upon_o a_o wrong_a bottom_n make_v it_o seem_v absolute_o occult_a for_o it_o be_v impossible_a to_o find_v a_o thing_n where_o it_o be_v not_o or_o to_o build_v firm_o upon_o a_o insufficient_a foundation_n whereas_o have_v it_o be_v right_o and_o true_a it_o be_v not_o to_o be_v imagine_v but_o some_o or_o other_o will_v have_v thereupon_o do_v something_o that_o will_v have_v stand_v against_o all_o wind_n and_o storm_n which_o none_o have_v do_v 3._o i_o observe_v that_o none_o dare_v venture_v to_o lay_v the_o whole_a no_o nor_o one_o half_a of_o the_o burden_n of_o the_o phinomena_n or_o effect_n of_o opium_n upon_o that_o foundation_n foresee_v doubtless_o that_o it_o can_v not_o bear_v they_o and_o that_o if_o they_o lay_v any_o more_o weight_n thereon_o the_o whole_a will_v totter_v and_o fall_v to_o the_o ground_n the_o project_n in_o every_o hypothesis_n be_v to_o persuade_v man_n of_o the_o truth_n thereof_o and_o the_o only_a way_n to_o do_v it_o be_v to_o solve_v all_o phenomena_n thereby_o for_o if_o it_o fail_v but_o in_o one_o it_o be_v a_o infallible_a sign_n of_o its_o insufficiency_n there_o be_v no_o reason_n to_o omit_v any_o of_o the_o phenomena_n if_o they_o can_v have_v discern_v that_o the_o hypothesis_n will_v have_v bear_v they_o therefore_o as_o have_v be_v intimate_v it_o imply_v a_o confession_n of_o its_o incompetency_n 4._o i_o observe_v that_o ancient_a author_n write_v of_o opium_n before_o it_o come_v to_o be_v of_o common_a and_o general_a use_n in_o the_o daytime_n with_o healthy_a person_n as_o it_o since_o be_v in_o many_o nation_n to_o cause_v a_o gay_a pleasant_a and_o good_a humour_n take_v off_o sadness_n melancholy_a and_o anxiety_n to_o cause_n assurance_n boldness_n courage_n bravery_n magnanimity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n promptitude_n in_o business_n expediteness_n and_o serenity_n to_o excite_v to_o venery_n etc._n etc._n which_o effect_n can_v be_v explain_v by_o that_o supposition_n of_o disable_n the_o spirit_n and_o that_o they_o use_v opium_n only_a medicinally_n for_o the_o sake_n of_o such_o other_o effect_n as_o may_v be_v tolerable_o well_o explicate_v by_o that_o hypothesis_n so_o that_o they_o have_v not_o any_o occasion_n nor_o inducement_n to_o look_v any_o far_o the_o effect_n they_o give_v it_o for_o be_v only_o 1._o to_o cause_v sleep_n 2._o to_o take_v off_o pain_n 3._o to_o stop_v flux_n 4._o to_o compose_v the_o spirit_n 5._o to_o cause_v perspiration_n and_o sweat_n all_o which_o be_v not_o inconsistent_a with_o the_o hypothesis_n of_o diminish_v or_o disable_n the_o spirit_n as_o the_o other_o be_v and_o therefore_o may_v well_o deceive_v they_o for_o first_o sleep_n be_v cause_v by_o diminish_v the_o spirit_n by_o labour_n watch_v etc._n etc._n as_o be_v most_o notorious_a over_o the_o whole_a world_n so_o other_o thing_n that_o diminish_v the_o spirit_n as_o bleed_v vomit_v purge_v and_o many_o other_o cause_n of_o diminish_v thereof_o do_v incline_v we_o to_o sleep_v second_o indolence_n or_o exemption_n from_o pain_n be_v cause_v by_o nothing_o more_o than_o want_v of_o spirit_n as_o in_o paralytical_a case_n stuporâ—_n obstruction_n or_o compression_n of_o the_o nerve_n syncopes_fw-la leipothymy_n deliquium_n faint_n after_o bleed_v and_o sleep_v which_o as_o be_v say_v be_v so_o much_o cause_v by_o loss_n of_o spirit_n etc._n etc._n three_o flux_n be_v stop_v or_o moderate_v by_o nothing_o better_a than_o sleep_n which_o general_o as_o be_v say_v proceed_v from_o loss_n of_o spirit_n what_o also_o stop_v or_o moderate_v flux_n more_o than_o want_v of_o the_o sense_n of_o the_o irritation_n of_o humour_n and_o what_o take_v away_o sense_n more_o than_o want_v of_o spirit_n thus_o want_v of_o sense_n by_o the_o absence_n of_o the_o spirit_n in_o paralytical_a intestine_n stop_v flux_n thus_o fail_v a_o paralytical_a bladder_n to_o express_v the_o urine_n so_o a_o palsy_n of_o the_o membrane_n
that_o include_v the_o glandule_n must_v as_o in_o sleep_n which_o relax_n they_o stop_v or_o moderate_v all_o defluxion_n catarrh_n etc._n etc._n because_o they_o be_v not_o sensible_a oâ—_n the_o irritation_n of_o the_o humour_n by_o quantity_n or_o quality_n which_o irritation_n cause_v the_o defluxion_n or_o catarrh_n by_o exciting_a the_o membrane_n to_o contract_v and_o thereby_o to_o squeeze_v out_o the_o humour_n contain_v in_o the_o glandule_n four_o the_o composure_n of_o the_o spirit_n be_v procure_v main_o by_o sleep_n which_o all_o loss_n of_o spirit_n as_o be_v show_v incline_v we_o to_o so_o bleed_v which_o diminish_v the_o spirit_n compose_v their_o fury_n in_o fever_n delirium_n madness_n etc._n etc._n five_o perspiration_n be_v cause_v by_o nothing_o more_o than_o sleep_v for_o we_o perspire_v twice_o as_o much_o in_o sleep_n as_o when_o we_o watch_v as_o be_v most_o manifest_o demonstrable_a by_o the_o statick_a experiment_n of_o weigh_v people_n nor_o be_v perspiration_n ever_o so_o great_a as_o in_o deliquium_n syncopes_fw-la leipothymy_n and_o such_o like_a deadish_fw-mi case_n which_o be_v cause_v by_o diminish_v or_o disable_n of_o the_o spirit_n nay_o it_o be_v so_o in_o animal_n quite_o dead_a for_o a_o little_a time_n while_o they_o be_v hot_a as_o be_v evident_a by_o like_a statick_a demonstration_n the_o true_a cause_n of_o which_o be_v relaxation_n of_o the_o pore_n skin_n etc._n etc._n for_o want_n of_o spirit_n to_o contract_n and_o constringe_v they_o as_o shall_v be_v full_o prove_v hereafter_o by_o god_n help_n these_o thing_n be_v doubtless_o the_o occasion_n of_o that_o hypothesis_n of_o diminish_v or_o disable_n the_o spirit_n by_o opium_n but_o how_o likely_a be_v they_o to_o err_v by_o establish_v it_o without_o any_o consideration_n of_o its_o enliven_a encourage_v and_o brisk_a effect_n as_o ovation_n of_o the_o spirit_n gaity_n bravery_n magnanimity_n euphory_n promptitude_n to_o venery_n etc._n etc._n which_o can_v never_o be_v solve_v by_o diminution_n or_o disability_n of_o the_o spirit_n till_o depression_n and_o elevation_n thereof_o be_v reconcilable_a and_o consistent_a at_o the_o same_o time_n in_o the_o same_o subject_n which_o can_v never_o be_v till_o disable_n and_o not_o disable_n be_v the_o same_o thing_n have_v not_o we_o then_o good_a reason_n to_o suspect_v that_o general_a foundation_n of_o diminish_v or_o disable_n the_o spirit_n by_o opium_n which_o be_v lay_v by_o such_o as_o never_o consider_v any_o thing_n of_o its_o generous_a and_o sprightly_a effect_n which_o as_o have_v be_v show_v be_v its_o constant_a and_o therefore_o most_o proper_a and_o genuine_a effect_n who_o can_v doubt_v then_o but_o they_o must_v err_v in_o lay_v a_o foundation_n quite_o contrary_a to_o the_o very_a property_n of_o opium_n 5._o i_o observe_v that_o all_o our_o modern_a author_n and_o physician_n receive_v the_o knowledge_n of_o opium_n its_o effect_n and_o uses_n from_o those_o ancient_n do_v use_v it_o only_o for_o the_o same_o end_n and_o purpose_v as_o they_o do_v and_o that_o our_o modern_a author_n live_v in_o these_o western_a part_n of_o the_o world_n very_o remote_a from_o the_o eastern_a country_n where_o it_o be_v use_v common_o and_o in_o large_a dose_n by_o people_n in_o health_n in_o the_o daytime_n to_o enliven_v invigorate_a and_o encourage_v they_o and_o cause_v the_o brave_a generous_a and_o magnanimous_a effect_n aforemention_v viz._n courage_n euphory_n etc._n etc._n and_o find_v no_o physician_n that_o go_v before_o they_o to_o mention_v these_o noble_a cordial_a and_o glorious_a effect_n and_o if_o they_o do_v at_o any_o time_n slight_o touch_v they_o to_o do_v it_o with_o all_o imaginable_a disregard_n neglect_v and_o contempt_n as_o if_o there_o be_v no_o heed_n to_o be_v take_v of_o they_o but_o as_o idle_a tale_n and_o improbable_a story_n be_v contrary_a and_o utter_o as_o they_o think_v inconsistent_a and_o irreconcilable_a with_o the_o daily_a and_o most_o notorious_a effect_n of_o opium_n observe_v among_o we_o and_o to_o the_o universal_a opinion_n of_o all_o author_n who_o state_v opium_n to_o be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n which_o can_v not_o produce_v as_o they_o conclude_v such_o contradictory_n and_o therefore_o to_o they_o utter_o incredible_a effect_n and_o fabulons_a flam_n arise_v as_o they_o fancy_v from_o some_o silly_a error_n as_o want_v of_o due_a observation_n in_o traveller_n mistake_a discourse_n and_o the_o like_a so_o that_o as_o the_o say_n be_v they_o let_v they_o in_o at_o one_o ear_n and_o out_o at_o the_o other_o there_o be_v no_o such_o contrary_a effect_n of_o any_o one_o thing_n to_o be_v observe_v in_o the_o whole_a creation_n and_o they_o be_v well_o assure_v of_o the_o other_o effect_n by_o daily_a experience_n and_o have_v never_o observe_v those_o lively_a effect_n for_o the_o several_a plain_a reason_n that_o you_o will_v meet_v in_o the_o follow_a paragraph_n have_v no_o cause_n to_o alter_v their_o opinion_n when_o all_o thing_n seem_v to_o they_o to_o make_v for_o their_o hypothesis_n for_o want_v of_o a_o notion_n of_o those_o brisk_a effect_n 6._o i_o observe_v that_o those_o brisk_a effect_n of_o opium_n be_v not_o take_v notice_n of_o by_o our_o physician_n nor_o indeed_o all_o thing_n consider_v do_v i_o well_o see_v how_o they_o shall_v without_o get_v out_o of_o the_o common_a road_n of_o observe_v which_o be_v sometime_o as_o i_o have_v find_v very_o useful_a upon_o such_o occasion_n for_o first_o opium_n be_v seldom_o if_o ever_o give_v in_o these_o western_a nation_n but_o to_o sick_a people_n as_o the_o ancient_n do_v who_o be_v utter_o incapable_a of_o those_o brisk_a effect_n or_o at_o least_o to_o any_o remarkable_a degree_n that_o may_v call_v for_o a_o particular_a or_o special_a advertency_n or_o attention_n without_o which_o they_o pass_v off_o as_o they_o come_v without_o any_o reflection_n thereupon_o and_o so_o signify_v nothing_o as_o if_o they_o have_v never_o happen_v second_o we_o as_o the_o ancient_n do_v general_o give_v opium_n when_o people_n be_v go_v to_o bed_n by_o which_o mean_v all_o opportunity_n of_o observation_n be_v lose_v because_o darkness_n and_o be_v alone_o hide_v or_o hinder_v the_o show_v of_o any_o such_o effect_n and_o the_o physician_n who_o only_a business_n it_o be_v to_o be_v more_o curious_a in_o such_o matter_n be_v go_v to_o his_o own_o rest_n though_o if_o he_o be_v present_a not_o likely_a to_o take_v any_o observation_n of_o such_o matter_n whereof_o he_o have_v least_o thought_n or_o belief_n as_o be_v in_o his_o opinion_n contrary_a to_o all_o reason_n sense_n experience_n and_o the_o opinion_n of_o all_o author_n of_o the_o stupefactive_a quality_n of_o opium_n in_o which_o they_o all_o agree_v three_o opium_n be_v as_o be_v say_v give_v in_o these_o country_n to_o cause_n sleep_n or_o such_o effect_n to_o which_o sleep_n conduce_v as_o compose_v the_o spirit_n cause_v indolence_n stop_v flux_n and_o promote_a perspiration_n and_o therefore_o always_o give_v with_o all_o careful_a direction_n and_o injunction_n that_o may_v conduce_v to_o that_o end_n as_o go_v to_o bed_n lie_v still_o put_v out_o light_n keep_v silence_n etc._n etc._n which_o concur_v with_o the_o opium_n cause_n sleep_n which_o be_v utter_o inconsistent_a with_o show_v any_o of_o those_o lively_a effect_n that_o belong_v only_o to_o a_o wake_a person_n to_o do_v so_o that_o all_o opportunity_n of_o observation_n be_v utter_o preclude_v now_o all_o the_o premise_n consider_v it_o can_v be_v conceive_v that_o such_o as_o set_v their_o mind_n upon_o contrary_a effect_n and_o expect_v no_o other_o much_o less_o contrary_a one_o against_o which_o also_o they_o be_v high_o prejudice_v by_o their_o reason_n experience_n and_o read_v shall_v observe_v such_o brisk_a effect_n if_o they_o do_v happen_v and_o how_o can_v a_o brisk_a humour_n courage_n easy_a undergo_n of_o labour_n promptitude_n to_o venus_n etc._n etc._n be_v observe_v in_o sick_a and_o infirm_a people_n lie_v in_o bed_n alone_z and_o in_o the_o dark_a or_o which_o render_v it_o utter_o impossible_a while_o they_o be_v asleep_a and_o the_o thing_n itself_o disbelieved_a and_o esteem_v contrary_a to_o common_a sense_n and_o the_o universal_a sentiment_n of_o the_o learned_a and_o all_o other_o therefore_o 7._o if_o after_o all_o any_o such_o brisk_a effect_n do_v ever_o happen_v it_o must_v be_v either_o not_o regard_v or_o if_o observe_v which_o be_v no_o way_n likely_a as_o be_v show_v you_o may_v be_v sure_a for_o the_o many_o plain_a reason_n and_o cause_n aforesaid_a that_o it_o be_v not_o impute_v to_o stupify_a opium_n as_o all_o esteem_v it_o but_o to_o any_o other_o cause_n or_o accident_n rather_o than_o to_o a_o thing_n well_o know_v to_o have_v quite_o contrary_a effect_n for_o instance_n if_o the_o sick_a person_n happen_v to_o be_v
etc._n as_o wine_n hot_a liquor_n and_o opium_n do_v 12._o opium_n do_v very_o much_o open_v the_o pore_n and_o cause_n perspiration_n etc._n etc._n which_o only_a heat_n as_o that_o in_o bath_n bagnio_n hot_a house_n and_o hot_a thing_n do_v but_o cold_a shut_v the_o pore_n as_o all_o know_v therefore_o 13._o opium_n cure_v and_o prevent_v cold_n which_o be_v another_o argument_n of_o its_o heat_n 14._o it_o be_v a_o great_a aphrodisiack_a or_o exciter_n to_o venery_n which_o cold_a thing_n chill_a but_o hot_a thing_n as_o cantharides_n bee_n pismire_n onion_n garlic_n leek_n rocket_n squill_n horse_n radish_n sem._n human._n etc._n etc._n do_v promote_v 15._o nothing_o cause_v indolence_n give_v internal_o but_o wine_n hot_a liquor_n etc._n etc._n as_o i_o can_v think_v of_o and_o opium_n cause_v it_o much_o after_o the_o same_o manner_n as_o wine_n do_v first_o cause_v mirth_n and_o jollity_n and_o upon_o increase_n of_o quantity_n very_o considerable_a indolence_n it_o be_v true_a that_o cold_a will_v external_o cause_v a_o stupor_n if_o it_o be_v intense_a so_o as_o to_o constringe_v the_o part_n and_o exclude_v the_o spirit_n but_o otherwise_o it_o make_v the_o feel_v more_o nice_a as_o all_o know_v by_o experience_n because_o every_o little_a hurt_n affect_v we_o more_o when_o we_o be_v cold_a than_o hot_a but_o this_o be_v not_o the_o case_n of_o relax_a opium_n which_o be_v use_v internal_o to_o take_v away_o pain_n as_o wine_n etc._n etc._n 16._o nothing_o take_v away_o the_o effect_n of_o opium_n or_o drunkeness_n better_o than_o cold_a thing_n internal_o and_o external_o as_o acid_n dip_v in_o cold_a water_n etc._n etc._n 17._o opium_n relax_n all_o part_n which_o heat_n do_v and_o cold_a constringe_n as_o be_v intimate_v 18._o wedelius_n confess_v though_o it_o make_v against_o what_o he_o say_v that_o he_o never_o observe_v a_o soporose_n distemper_n where_o there_o be_v not_o a_o preternatural_a heat_n opiolog_fw-la lib._n 1._o sect._n 1_o cap._n 12._o p._n 46._o 19_o if_o it_o cause_v sleep_n by_o its_o cold_a quality_n than_o all_o thing_n that_o be_v cold_a will_v do_v it_o proportionable_o cucumber_n purslane_n etc._n etc._n will_v be_v so_o great_a hypnotick_n that_o we_o shall_v not_o be_v able_a to_o eat_v a_o drachm_n of_o they_o but_o that_o they_o will_v cause_v a_o great_a sopor_fw-la but_o there_o be_v no_o such_o thing_n and_o hot_a thing_n be_v much_o more_o apt_a to_o cause_v sleep_n or_o a_o sopor_fw-la as_o wine_n hot_a spirit_n onion_n garlic_n and_o such_o like_a 20._o opium_n cause_v a_o redness_n or_o efflorescence_n of_o the_o skin_n make_v it_o sensible_o warm_a as_o heat_n wine_n and_o strong_a liquor_n do_v 21._o it_o cause_v also_o a_o itch_a of_o the_o skin_n which_o only_o hot_a thing_n do_v 22._o half_n a_o drachm_n of_o opium_n in_o clyster_n have_v cause_v a_o violent_a heat_n in_o the_o gut_n 23._o it_o stop_v diarrheas_n or_o looseness_n which_o cold_a cause_n 24._o it_o stop_v defluxion_n cough_n etc._n etc._n which_o cold_a cause_n 25._o to_o pin_v up_o all_o its_o predominant_a principle_n appear_v by_o autopsie_n upon_o its_o chemical_a analysis_n to_o be_v volatile_a salt_n and_o sulphur_n beside_o this_o opinion_n of_o the_o coldness_n of_o opium_n be_v very_o much_o explode_v and_o indeed_o it_o be_v so_o apparent_o false_a and_o absurd_a that_o i_o shall_v not_o have_v think_v it_o worth_a while_n to_o argue_v against_o it_o but_o that_o it_o lay_v so_o in_o my_o way_n that_o regular_o i_o can_v not_o well_o avoid_v it_o without_o breach_n of_o order_n and_o method_n i_o may_v have_v add_v that_o it_o resolve_v attenuate_v etc._n etc._n but_o it_o be_v needless_a to_o say_v any_o more_o it_o be_v very_o false_a and_o erroneous_a that_o it_o stop_v flux_n by_o incrassate_v and_o bind_v which_o be_v account_v cold_a quality_n if_o so_o how_o shall_v it_o stop_v they_o when_o pound_n of_o incrassative_n and_o binder_n have_v fail_v though_o the_o opium_n be_v give_v only_o in_o the_o quantity_n of_o a_o grain_n or_o two_o how_o shall_v it_o stop_v or_o moderate_a flux_n even_o while_o it_o be_v yet_o at_o stomach_n as_o it_o most_o certain_o do_v it_o bear_v as_o etmuller_n well_o observe_v no_o proportion_n to_o the_o blood_n and_o humour_n to_o have_v any_o effect_n that_o may_v be_v remarkable_a upon_o they_o for_o a_o grain_n be_v but_o as_o 1_o to_o 115200_o to_o the_o blood_n of_o he_o that_o have_v 20_o pound_n of_o blood_n which_o a_o ordinary_a man_n have_v beside_o how_o can_v altenuative_n resolver_n and_o discusser_n incrassate_fw-it or_o bind_z but_o more_o especial_o how_o can_v so_o great_a a_o relaxer_n of_o part_n be_v a_o constringer_n thereof_o that_o be_v perfect_a contradiction_n and_o how_o can_v a_o mere_a sal_fw-la volatile_a oleosum_fw-la in_o which_o all_o its_o virtue_n lie_v as_o will_v plain_o appear_v thicken_v and_o bind_v the_o truth_n be_v that_o it_o stop_v flux_n as_o sleep_n do_v by_o take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o solicit_v the_o part_n to_o contract_n and_o so_o to_o extrude_v and_o squeeze_v they_o out_o it_o promote_v perspiration_n by_o relax_v the_o pore_n as_o sleep_n do_v it_o also_o seem_v to_o thicken_v rheum_n as_o sleep_n do_v because_o it_o cause_v sleep_n or_o at_o least_o take_v away_o a_o sense_n of_o the_o irritation_n of_o the_o rheum_n be_v thereby_o suffer_v to_o stay_v till_o it_o thicken_v by_o the_o heat_n of_o the_o body_n the_o irritation_n also_o at_o windpipe_n be_v less_o because_o the_o flux_n of_o the_o rheum_n be_v moderate_v for_o the_o reason_n aforesaid_a but_o of_o these_o thing_n more_o full_o when_o we_o come_v to_o explain_v the_o cause_n or_o cause_n of_o the_o effect_n of_o opium_n chap._n x._o it_o be_v prove_v that_o opium_n send_v no_o fume_n etc._n etc._n from_o the_o stomach_n to_o the_o head_n brain_n etc._n etc._n and_o therefore_o that_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n etc._n etc._n by_o that_o mean_n though_o the_o opinion_n of_o the_o cold_a of_o opium_n be_v much_o explode_v that_o of_o fume_n vapour_n or_o aura_n arise_v from_o the_o opium_n at_o stomach_n and_o mount_v up_o to_o the_o brain_n etc._n etc._n be_v as_o much_o receive_v and_o embrace_v i_o know_v none_o but_o such_o as_o think_v it_o absolute_o necessary_a consider_v that_o it_o be_v most_o certain_a and_o allow_v by_o all_o observe_a man_n that_o opium_n produce_v all_o or_o most_o of_o its_o effect_n while_o it_o be_v at_o stomach_n that_o the_o genus_fw-la neruâ—sum_fw-la be_v most_o concern_v in_o its_o operation_n and_o that_o as_o be_v say_v there_o be_v no_o operation_n or_o action_n but_o by_o contact_n so_o that_o the_o modern_n acquiesce_v in_o the_o necessity_n of_o its_o operate_n that_o way_n because_o they_o can_v conceive_v no_o other_o which_o be_v no_o proof_n but_o a_o defect_n of_o their_o conception_n look_v upon_o it_o as_o invincible_a and_o uncontrollable_a evidence_n oâ—_n its_o operate_n by_o detachment_n of_o fume_n or_o 〈◊〉_d send_v up_o to_o the_o brain_n from_o the_o stomach_n which_o appear_v so_o undeniable_o conclusive_a that_o neither_o the_o want_n of_o a_o sensible_a passage_n nor_o any_o other_o inconvenience_n signify_v any_o thing_n with_o they_o to_o the_o contrary_a therefore_o it_o become_v a_o establish_a foundation_n by_o common_a consent_n only_o they_o differ_v as_o be_v show_v in_o the_o manner_n how_o those_o fume_n produce_v the_o effect_n of_o opium_n and_o well_o they_o may_v see_v there_o be_v no_o such_o thing_n nor_o possibility_n if_o they_o be_v of_o ever_o explicate_v the_o various_a effect_n of_o opium_n by_o that_o mean_n as_o will_v manifest_o appear_v i_o confess_v that_o if_o opium_n operate_v by_o such_o fume_n pass_v from_o the_o stomach_n to_o the_o brain_n etc._n etc._n it_o will_v be_v easy_a to_o conceive_v how_o it_o shall_v diminish_v or_o disable_v nay_o utter_o ruin_v the_o animal_n spirit_n and_o indeed_o impossible_a rational_o to_o conceive_v how_o they_o can_v do_v otherwise_o but_o then_o the_o enliven_a invigorate_n and_o encourage_v effect_n of_o opium_n which_o be_v its_o constant_a and_o most_o genuine_a off_o spring_n will_v lie_v upon_o our_o hand_n without_o any_o possibility_n of_o give_v a_o account_n thereof_o for_o certain_o dull_a heavy_a unnatural_a undigested_a and_o cloudy_a fume_n or_o vapour_n can_v not_o advantage_v the_o animal_n spirit_n cause_v a_o triumph_n or_o ovation_n thereof_o at_o their_o access_n courage_n serenity_n promptitude_n magnanimity_n euphory_n inclination_n to_o venery_n etc._n etc._n which_o we_o be_v most_o oblige_v to_o regard_n as_o be_v its_o most_o natural_a and_o proper_a effect_n this_o opinion_n of_o the_o modern_n do_v presume_v or_o suppose_v for_o they_o prove_v nothing_o first_o that_o fume_n
increase_v more_o and_o more_o and_o make_v one_o more_o and_o more_o remote_a from_o wake_v 4._o why_o shall_v warm_a bath_n fomentation_n feetwash_n head-washes_a warm_a moist_a wether_n the_o act_n of_o venery_n the_o pleasure_n of_o sweet_a melody_n gentle_a rub_v of_o the_o head_n in_o a_o pleasant_a manner_n scratch_v the_o back_n where_o it_o itch_v and_o all_o gentle_a pleasure_n that_o be_v consistent_a with_o lie_v or_o sit_v still_o which_o do_v all_o cause_n a_o very_a free_a perspiration_n of_o fume_n at_o the_o pore_n that_o be_v then_o most_o certain_o open_v by_o all_o those_o cause_n as_o may_v be_v prove_v by_o statick_a demonstration_n magnify_v glass_n etc._n etc._n cause_n sleep_n see_v they_o all_o cause_n a_o spend_v of_o the_o fume_n obj._n some_o half-witted_a unthinking_a caviller_n may_v say_v that_o such_o thing_n stir_v up_o the_o vapour_n etc._n etc._n answ._n what_o such_o mean_a by_o vapour_n stir_v be_v not_o easy_o determinable_a but_o this_o i_o know_v that_o all_o stir_n of_o humour_n or_o any_o other_o thing_n hinder_v sleep_n and_o that_o the_o long_o such_o cause_n of_o open_v the_o pore_n and_o consequent_o of_o perspire_a fume_n do_v last_o the_o more_o we_o be_v incline_v by_o they_o to_o sleep_n so_o that_o the_o more_o our_o fume_n have_v be_v spend_v the_o more_o we_o be_v incline_v to_o sleep_v which_o be_v a_o strange_a contradiction_n if_o fume_n be_v the_o cause_n of_o sleep_n i_o can_v but_o smile_v to_o think_v how_o most_o physician_n come_v to_o call_v several_a thing_n vapour_n first_o they_o say_v that_o sleep_n be_v from_o vapour_n then_o call_v every_o thing_n vapour_n right_a or_o wrong_n that_o incline_v we_o to_o sleep_v by_o reason_n of_o that_o false_a supposition_n how_o then_o come_v camphire_n not_o to_o be_v a_o great_a causer_n of_o sleep_n that_o be_v so_o apt_a to_o evaporate_v 5._o fear_v sorrow_n grief_n melancholy_n depression_n of_o spirit_n cold_a etc._n etc._n do_v most_o certain_o close_v the_o pore_n as_o appear_v by_o statick_a experiment_n by_o which_o mean_v vapour_n be_v much_o crowd_v in_o the_o body_n yet_o all_o such_o grievance_n do_v hinder_v sleep_n as_o they_o also_o do_v the_o effect_n of_o opium_n and_o drunkenness_n therefore_o they_o do_v not_o proceed_v from_o fume_n as_o the_o world_n imagine_v for_o then_o these_o thing_n that_o crowd_v in_o the_o fume_n and_o vapour_n will_v promote_v not_o hinder_v sleep_n 6._o if_o fume_n be_v the_o cause_n of_o sleep_n then_o be_v the_o cause_n of_o sleep_n and_o vertigo_n as_o the_o vaporanians_n allow_v the_o same_o it_o follow_v then_o that_o we_o can_v never_o sleep_v without_o a_o vertigo_n 7._o many_o as_o dr._n willis_n say_v eat_v their_o meat_n take_v their_o drink_n etc._n etc._n as_o other_o people_n yet_o do_v not_o sleep_v at_o all_o for_o many_o week_n together_o which_o be_v impossible_a if_o the_o fume_n of_o meat_n and_o drink_v cause_v sleep_n for_o they_o by_o eat_v and_o drink_v must_v have_v those_o fume_n and_o consequent_o sleep_v as_o other_o people_n if_o that_o be_v true_a three_o they_o suppose_v and_o take_v it_o for_o grant_v which_o i_o do_v not_o for_o i_o know_v the_o contrary_a that_o opium_n while_o it_o be_v at_o stomach_n can_v affect_v the_o brain_n etc._n etc._n no_o other_o way_n but_o by_o fume_n which_o be_v a_o most_o groundless_a supposition_n for_o 1._o how_o shall_v a_o lump_n of_o curd_n at_o stomach_n or_o the_o have_v of_o a_o knife_n swallow_v and_o many_o such_o thing_n which_o can_v send_v no_o fume_n to_o the_o head_n cause_n convulsion_n headache_n vertigo_n syncopes_fw-la leipothymy_n of_o the_o whole_a man_n manias_fw-la furor_n etc._n etc._n if_o there_o be_v not_o another_o way_n for_o thing_n to_o affect_v the_o nervosum_fw-la genus_fw-la etc._n etc._n while_n at_o stomach_n beside_o send_v up_o vapour_n to_o do_v it_o but_o of_o this_o matter_n to_o show_v how_o a_o thing_n at_o stomach_n may_v affect_v the_o brain_n and_o the_o whole_a system_n of_o the_o nerve_n etc._n etc._n and_o how_o opium_n do_v it_o without_o fume_n the_o 17_o 18_o 19_o 20_o etc._n etc._n chapter_n will_v show_v you_o at_o large_a therefore_o i_o shall_v say_v no_o more_o of_o this_o at_o present_a for_o it_o be_v fit_a for_o we_o first_o to_o overthrow_v that_o supposition_n of_o fume_n and_o vapour_n before_o we_o establish_v our_o own_o for_o far_a satisfaction_n then_o as_o to_o that_o general_a supposition_n of_o fume_n let_v we_o due_o and_o full_o consider_v thing_n for_o it_o be_v not_o a_o slight_a matter_n to_o proceed_v against_o a_o general_n opinion_n that_o have_v continue_v through_o all_o age_n or_o to_o wipe_v off_o the_o prejudices_fw-la acquire_v thereby_o observe_v 1._o that_o the_o brain_n be_v a_o principal_a part._n 2._o that_o it_o be_v very_o soft_a tender_a and_o next_o to_o a_o fluid_a 3._o that_o very_o small_a fine_a and_o gentle_a thing_n do_v high_o offend_v it_o as_o the_o effluvia_n of_o sweet_a or_o ill-scented_n thing_n cause_v hysterick_a and_o epileptical_a fit_n syncopes_fw-la faint_n etc._n etc._n it_o be_v also_o notorious_a among_o we_o physician_n that_o a_o little_a fume_v scarce_o sensible_a as_o to_o quantity_n or_o quality_n rise_v from_o a_o toe_n finger_n &c_n &c_n and_o arrive_v at_o the_o brain_n cause_v dreadful_a epileptical_a fit_n vertigo_n &c._n &c._n 4._o that_o our_o wise_a and_o provident_a creator_n have_v therefore_o secure_v and_o fortify_v all_o the_o avenue_n of_o the_o brain_n in_o a_o more_o particular_a manner_n by_o several_a circumvallation_n viz._n first_o with_o the_o pia_fw-la mater_fw-la second_o with_o the_o dura_n mater_n call_v so_o from_o its_o hardness_n solidity_n and_o strength_n three_o with_o a_o strong_a skull_n of_o a_o round_a or_o arch_a figure_n four_o with_o the_o pericranium_n all_o which_o belong_v to_o it_o particular_o beside_o other_o integument_n common_a to_o it_o with_o other_o part_n as_o 1._o the_o skin_n 2._o the_o cuticle_n 3._o the_o membrana_fw-la carnosa_fw-la 4._o the_o periostium_fw-la all_o which_o do_v surround_v it_o and_o after_o all_o it_o be_v thatch_v as_o it_o be_v with_o hair_n 5._o that_o the_o same_o providence_n have_v take_v care_n which_o be_v very_o observable_a that_o none_o of_o the_o object_n of_o sensation_n nor_o probable_o any_o particle_n or_o effluvium_fw-la that_o fly_v from_o they_o shall_v ever_o reach_v the_o brain_n but_o only_o bare_a impulse_n and_o they_o not_o immediate_o convey_v but_o by_o the_o intervention_n of_o a_o fine_a tenuious_a soft_a gentle_a and_o most_o agreeable_a aura_n viz._n the_o animal_n spirit_n lest_o any_o offence_n shall_v be_v give_v in_o the_o least_o manner_n to_o this_o most_o tender_a delicate_a principal_a part_n and_o royal_a seat_n of_o the_o soul_n all_o which_o care_n have_v never_o be_v without_o necessity_n for_o god_n and_o nature_n do_v nothing_o in_o vain_a and_o if_o you_o will_v due_o consider_v the_o organ_n of_o sensation_n that_o be_v near_o the_o brain_n you_o will_v find_v that_o they_o be_v contrive_v as_o shutter_n to_o exclude_v all_o extraneous_a particle_n from_o the_o brain_n for_o impulse_n may_v have_v be_v contrive_v without_o their_o intervention_n because_o they_o do_v not_o alter_v or_o improve_v the_o impulse_n receive_v from_o object_n for_o if_o they_o do_v we_o shall_v not_o have_v true_a notice_n of_o thing_n and_o see_v they_o do_v not_o alter_v or_o improve_v the_o impulse_n of_o what_o use_n shall_v they_o be_v but_o to_o exclude_v extraneous_a particle_n eume_n effluvia_n &c._n &c._n for_o instance_n the_o tremulous_a motion_n of_o the_o air_n in_o the_o case_n of_o sound_n will_v have_v as_o true_o hit_v the_o auditory_a nerve_n or_o membrane_n without_o the_o tympan_n and_o very_o often_o much_o true_a without_o it_o because_o of_o the_o several_a fault_n and_o disorder_n that_o it_o be_v liable_a to_o yet_o so_o necessary_a be_v it_o think_v by_o the_o best_a of_o judge_n who_o can_v err_v that_o it_o be_v rather_o to_o be_v place_v there_o with_o all_o its_o inconvenience_n that_o may_v follow_v than_o any_o way_n expose_v the_o brain_n though_o to_o the_o most_o gentle_a of_o body_n viz._n the_o air_n by_o which_o in_o all_o probability_n the_o animal_n spirit_n themselves_o be_v nourish_v or_o sustain_v be_v it_o not_o that_o extraneous_a particle_n or_o air_n will_v offend_v the_o brain_n what_o need_n be_v there_o of_o the_o tympan_n when_o we_o know_v as_o well_o by_o experience_n as_o by_o the_o aforesaid_a reason_n that_o a_o dog_n etc._n etc._n can_v hear_v as_o well_o without_o it_o upon_o the_o first_o take_v it_o off_o but_o that_o the_o hear_v will_v afterward_o decay_v because_o the_o brain_n etc._n etc._n be_v expose_v will_v be_v injure_v what_o be_v evident_a in_o the_o case_n of_o the_o ear_n may_v be_v make_v so_o
any_o regular_a thinker_n without_o my_o help_n but_o all_o be_v not_o such_o and_o the_o prejudices_fw-la general_n and_o inveterate_a and_o of_o some_o thousand_o of_o year_n stand_v have_v continue_v through_o all_o age_n to_o this_o day_n and_o i_o will_v fain_o quite_o put_v out_o this_o false_a light_n that_o like_a will_n of_o the_o wisp_n have_v bring_v many_o a_o man_n into_o the_o pit_n of_o destruction_n or_o grave_a while_o physician_n be_v guide_v thereby_o therefore_o it_o be_v no_o slight_a work_n to_o undeceive_v many_o and_o a_o very_a good_a work_n if_o possible_a to_o undeceive_v all_o i_o will_v left_a what_o i_o have_v say_v be_v not_o sufficient_a to_o that_o end_n add_v somewhat_o more_o to_o the_o same_o purpose_n though_o i_o doubt_v some_o will_v not_o be_v convince_v till_o i_o show_v they_o how_o thing_n while_n at_o stomach_n may_v cause_v all_o the_o effect_n of_o opium_n by_o a_o sensible_a operation_n without_o the_o help_n of_o fume_n vapour_n effluvia_n aura_n or_o any_o any_o such_o thing_n which_o have_v be_v the_o asylum_n of_o the_o shortsighted_a that_o can_v see_v no_o other_o mean_n and_o therefore_o as_o be_v say_v conclude_v thing_n must_v be_v as_o they_o think_v presume_v that_o nothing_o can_v be_v that_o they_o do_v not_o see_v a_o special_a inference_n and_o a_o very_a improve_n one_o which_o must_v cause_v people_n never_o to_o seek_v for_o any_o thing_n for_o why_o shall_v they_o that_o think_v there_o be_v nothing_o but_o what_o they_o see_v look_v any_o far_o to_o proceed_v then_o 14._o it_o be_v agree_v on_o all_o hand_n as_o i_o take_v it_o that_o the_o animal_n spirit_n be_v not_o generate_v till_o there_o be_v a_o appulse_n of_o the_o blood_n at_o the_o brain_n can_v it_o therefore_o be_v imagine_v that_o indulgent_a and_o wise_a nature_n shall_v contrive_v a_o speedy_a way_n to_o destroy_v diminish_v or_o disable_v the_o spirit_n by_o fume_n and_o vapour_n out_o of_o the_o stomach_n than_o to_o generate_v they_o these_o be_v not_o the_o way_n of_o equal_a nature_n which_o destroy_v and_o generate_v by_o the_o same_o road_n so_o that_o if_o animal_n spirit_n be_v generate_v by_o the_o blood_n they_o be_v diminish_v by_o some_o defect_n therein_o as_o want_v of_o matter_n in_o the_o blood_n for_o that_o purpose_n the_o blood_n not_o arrive_v at_o the_o brain_n and_o the_o like_a note_v that_o i_o speak_v in_o the_o last_o paragraph_n of_o diminish_v or_o destroy_v not_o bare_a disable_n the_o spirit_n for_o the_o spirit_n or_o sensitive_a soul_n may_v be_v depress_v or_o disable_v for_o some_o time_n and_o excite_v or_o elevate_v by_o other_o mean_n than_o that_o of_o the_o blood_n as_o by_o pleasure_n or_o displeasure_n joy_n or_o grief_n etc._n etc._n thus_o good_a news_n or_o the_o pleasure_n of_o any_o of_o the_o sense_n enliven_v invigorate_a or_o elevate_v the_o spirit_n or_o sensitive_a soul_n in_o a_o moment_n this_o be_v the_o way_n that_o god_n have_v provide_v for_o we_o upon_o sudden_a exigency_n deliquium_n lepothymy_n etc._n etc._n and_o thus_o cordial_n work_v so_o speedy_o as_o you_o will_v find_v hereafter_o so_o may_v there_o be_v a_o sudden_a depression_n of_o the_o spirit_n as_o by_o ill_a news_n pain_n etc._n etc._n which_o if_o you_o will_v be_v please_v to_o remember_v will_v much_o illustrate_a thing_n hereafter_o 15._o the_o ordinary_a strainer_n of_o the_o body_n be_v so_o order_v that_o they_o will_v not_o admit_v particle_n of_o another_o figure_n especial_o if_o large_a than_o the_o proper_a particle_n much_o more_o shall_v it_o be_v so_o with_o the_o principal_a strainer_n of_o the_o whole_a body_n i_o mean_v the_o brain_n both_o for_o its_o safety_n and_o of_o the_o whole_a which_o depend_v upon_o the_o animal_n spirit_n that_o be_v strain_v or_o separate_v from_o the_o blood_n in_o the_o brain_n therefore_o the_o particle_n of_o opium_n which_o be_v esteem_v gross_a by_o all_o however_o be_v more_o so_o than_o the_o most_o tenuious_a animal_n spirit_n can_v enter_v into_o the_o pore_n of_o the_o brain_n to_o diminish_v or_o disable_v the_o animal_n spirit_n in_o case_n its_o fume_v arrive_v there_o 16._o it_o be_v never_o the_o method_n of_o nature_n to_o send_v thing_n crude_a unprepared_a and_o undigested_a into_o the_o inmost_a and_o principal_a recess_n and_o part_n of_o the_o body_n without_o pass_v gradual_o by_o the_o several_a digestion_n concoction_n change_n percolation_n circulation_n etc._n etc._n preparatory_a thereunto_o therefore_o it_o will_v not_o permit_v crude_a and_o indigested_a fume_n any_o access_n to_o the_o brain_n till_o they_o have_v as_o it_o be_v perform_v their_o quarentine_n elsewhere_o nor_o will_v nature_n which_o always_o act_v consentaneous_a to_o itself_o provide_v any_o passage_n for_o such_o rude_a and_o crude_a foreigner_n and_o stranger_n to_o ravage_v the_o principal_a part_n of_o a_o animal_n 17._o they_o can_v pass_v by_o the_o artery_n which_o carry_v nothing_o out_o of_o the_o stomach_n but_o all_o into_o it_o or_o towards_o it_o and_o that_o with_o a_o violent_a motion_n which_o oppose_v any_o thing_n that_o will_v pass_v that_o way_n 18._o nor_o by_o the_o vein_n which_o carry_v nothing_o into_o the_o brain_n but_o if_o they_o enter_v the_o vein_n at_o stomach_n they_o must_v thence_o pass_v into_o the_o right_a ventricle_n of_o the_o heart_n where_o be_v rarefy_v by_o heat_n they_o must_v take_v up_o much_o room_n and_o sad_o discompose_v the_o motion_n of_o the_o blood_n and_o also_o enter_v this_o principal_a part_n in_o a_o crude_a condition_n though_o much_o better_a able_a to_o bear_v they_o than_o the_o brain_n then_o must_v they_o pass_v into_o the_o lung_n where_o you_o may_v be_v sure_a they_o will_v be_v so_o saucy_a as_o to_o take_v up_o the_o uppermost_a room_n and_o how_o they_o will_v be_v bring_v down_o again_o into_o the_o left_a ventricle_n of_o the_o heart_n which_o they_o must_v vouchsase_v to_o do_v before_o they_o can_v get_v into_o the_o brain_n none_o can_v tell_v there_o then_o must_v they_o stick_v and_o cause_v a_o asthma_n unless_o the_o man_n have_v the_o good_a luck_n to_o be_v rid_v of_o these_o rover_n by_o othing_n and_o then_o joy_n be_v with_o they_o as_o there_o wiâ—_n be_v when_o they_o be_v go_v they_o be_v lose_v and_o never_o arrive_v at_o the_o brain_n and_o if_o it_o can_v be_v conceive_v that_o they_o condescend_v to_o come_v down_o from_o the_o lung_n contrary_a to_o their_o levity_n which_o be_v not_o to_o be_v think_v what_o prank_n must_v they_o play_v in_o 〈◊〉_d leave_v ventricle_n of_o the_o heart_n and_o what_o at_o 〈◊〉_d consider_v it_o can_v bear_v the_o 〈◊〉_d 〈◊〉_d 〈◊〉_d have_v be_v show_v whereas_o in_o this_o case_n there_o must_v be_v a_o continual_a stream_n thereof_o and_o consequent_o a_o discontinuance_n of_o the_o blood_n and_o its_o motion_n see_v then_o how_o little_a think_v they_o must_v have_v that_o assert_v it_o be_v convey_v with_o the_o blood_n either_o to_o the_o vein_n or_o artery_n 19_o nor_o by_o the_o lymphduct_n for_o than_o they_o must_v contrary_a to_o their_o natural_a levity_n descend_v into_o the_o receptaculum_fw-la chyli_n and_o out_o of_o the_o subclavial_o into_o the_o right_a ventricle_n of_o the_o heart_n and_o afterward_o run_v all_o that_o wild_a risque_n mention_v in_o the_o last_o paragraph_n which_o be_v show_v to_o be_v impossible_a 20._o nor_o by_o the_o nerve_n for_o than_o they_o must_v either_o run_v up_o in_o the_o road_n of_o the_o animal_n spirit_n or_o in_o some_o by-way_n if_o they_o pass_v by_o the_o road_n of_o the_o spirit_n then_o must_v the_o spirit_n be_v stop_v for_o that_o time_n which_o be_v no_o short_a one_o and_o we_o suffer_v a_o paralysis_n of_o the_o stomach_n all_o that_o time_n or_o be_v much_o disturb_v and_o interrupt_v then_o shall_v we_o have_v convulsion_n or_o at_o least_o some_o degree_n of_o a_o paralysis_n of_o the_o stomach_n and_o if_o they_o pass_v by_o some_o by-way_n or_o road_n beside_o that_o of_o the_o animal_n spirit_n then_o must_v it_o be_v a_o full_a or_o a_o empty_a one_o if_o full_a that_o humour_n as_o suppose_v a_o succus_fw-la nutricius_fw-la for_o once_o must_v be_v disturb_v and_o discontinue_v as_o the_o animal_n spirit_n be_v show_v to_o be_v and_o if_o empty_a it_o will_v follow_v that_o nature_n have_v void_a and_o useless_a duct_n which_o none_o ever_o have_v the_o folly_n or_o confidence_n to_o assert_v or_o that_o nature_n contrive_v they_o for_o that_o purpose_n which_o be_v as_o have_v be_v show_v direct_o against_o its_o method_n and_o advantage_n but_o after_o all_o whither_o will_v you_o have_v they_o march_v in_o this_o by-road_n for_o they_o can_v not_o mix_v or_o communicate_v as_o good_a luck_n be_v with_o the_o spirit_n and_o if_o they_o do_v it_o be_v
impossible_a it_o shall_v be_v without_o such_o disturbance_n as_o i_o mention_v will_v follow_v if_o they_o pass_v in_o the_o road_n of_o the_o spirit_n it_o be_v not_o common_a sense_n that_o such_o câ—de_a blast_n shall_v meliorate_v or_o enliven_v the_o spirit_n to_o cause_v briskness_n bravery_n serenity_n courage_n magnanimity_n as_o opium_n do_v much_o less_o if_o those_o fume_n stop_v and_o crowd_v in_o the_o brain_n and_o any_o way_n hinder_v the_o generation_n of_o animal_n spirit_n as_o the_o common_a assertion_n be_v the_o like_a be_v to_o be_v say_v of_o their_o pass_v between_o the_o pia_fw-la mater_fw-la and_o the_o medullary_a part_n of_o the_o nerve_n which_o can_v be_v allow_v because_o of_o its_o close_a adherence_n thereto_o with_o this_o addition_n that_o they_o will_v constant_o cause_v a_o violent_a headache_n which_o opium_n and_o meal_n to_o which_o fume_n be_v particular_o attribute_v do_v often_o cure_v so_o if_o they_o get_v up_o to_o the_o head_n between_o the_o pia_n and_o dura_n mater_n it_o be_v headache_n and_o not_o the_o symptom_n of_o opium_n that_o they_o will_v produce_v which_o headache_n as_o be_v say_v opium_n and_o meal_n do_v cure_v 21._o last_o if_o they_o pass_v by_o any_o mean_n quite_o on_o the_o outside_n of_o the_o nerve_n and_o their_o membrane_n viz._n the_o pia_n and_o dura_n mater_n then_o must_v they_o take_v their_o lodgement_n if_o within_o the_o skull_n between_o the_o dura_n mater_n and_o the_o skull_n and_o produce_v no_o other_o symptom_n but_o a_o headache_n which_o as_o be_v say_v opium_n and_o meal_n rather_o cure_v than_o produce_v and_o if_o without_o the_o skull_n it_o be_v quite_o beside_o the_o cushion_n and_o the_o vaporarian_n own_o intention_n for_o in_o all_o these_o last_o case_n they_o can_v not_o affect_v the_o animal_n spirit_n for_o good_a or_o evil_n many_o and_o very_o many_o thing_n may_v be_v add_v to_o show_v the_o impossibility_n inconvenience_n incoherence_n absurdity_n etc._n etc._n that_o attend_v the_o passage_n of_o the_o fume_n and_o vapour_n into_o the_o brain_n head_n etc._n etc._n 22._o i_o have_v forgotâ—_n mention_v the_o absurdity_n of_o its_o pass_v up_o at_o gullet_n and_o so_o to_o the_o head_n because_o i_o can_v not_o imagine_v that_o any_o one_o will_v be_v so_o beastly_a a_o animal_n as_o to_o belch_v up_o a_o argument_n of_o that_o kind_n consider_v our_o very_a sense_n tell_v we_o that_o what_o come_v up_o that_o way_n pass_v out_o at_o mouth_n or_o nostril_n and_o because_o if_o it_o be_v so_o the_o operation_n of_o opium_n etc._n etc._n will_v be_v in_o proportion_n to_o our_o belch_a which_o be_v ridiculous_a 23._o the_o great_a comfort_n of_o a_o cordial_n be_v at_o first_o or_o soon_o after_o it_o be_v take_v but_o if_o '_o its_o comfort_n be_v by_o fume_n or_o essluvia_n pass_v to_o the_o blood_n or_o any_o where_o beside_o the_o comfort_n will_v as_o their_o cause_n of_o fume_n do_v increase_v for_o a_o long_a time_n and_o be_v more_o after_o a_o good_a while_n than_o at_o first_o so_o 24._o if_o opium_n operate_v by_o fume_n while_o at_o stomach_n which_o must_v gradual_o increase_v continual_o how_o come_v opium_n to_o be_v at_o the_o height_n of_o its_o operation_n in_o a_o short_a time_n viz._n in_o about_o half_a a_o hour_n after_o it_o begin_v sensible_o to_o operate_v or_o a_o hour_n at_o far_a and_o not_o increase_v continual_o in_o its_o operation_n as_o their_o pretend_a cause_n the_o fume_n must_v do_v by_o continual_a steam_a 25._o if_o opium_n operate_v by_o send_v fume_n by_o passage_n etc._n etc._n from_o the_o stomach_n to_o the_o brain_n i_o shall_v think_v that_o when_o it_o have_v get_v out_o of_o the_o stomach_n as_o into_o the_o intestine_n lacteal_v vein_n etc._n etc._n there_o shall_v be_v a_o kind_n of_o interval_n of_o its_o operation_n which_o be_v never_o observe_v till_o it_o get_v into_o the_o blood_n again_o therefore_o it_o do_v not_o operate_v by_o fume_n for_o the_o pylorus_n be_v always_o shut_v but_o when_o somewhat_o be_v send_v downward_o which_o will_v hinder_v the_o mount_a of_o the_o vapour_n into_o the_o stomach_n in_o order_n to_o pass_v to_o the_o brain_n 26._o if_o vapour_n be_v the_o cause_n of_o sleep_n after_o meal_n than_o shall_v we_o be_v more_o sleepy_a two_o or_o three_o hour_n after_o meal_n because_o of_o the_o abundance_n of_o the_o fume_n that_o will_v be_v crowd_v into_o the_o brain_n by_o that_o time_n but_o we_o be_v more_o sleepy_a present_o after_o meal_n and_o if_o we_o indulge_v it_o but_o for_o a_o quarter_n of_o a_o hour_n we_o be_v refresh_v and_o far_o from_o sleepiness_n afterward_o though_o the_o fume_n if_o that_o hypothesis_n be_v true_a will_v be_v much_o more_o at_o brain_n two_o or_o three_o hour_n after_o the_o meal_n so_o it_o be_v in_o the_o case_n of_o wine_n if_o one_o take_v a_o short_a nap_n after_o some_o glass_n he_o may_v drink_v a_o great_a many_o afterward_o without_o be_v sleepy_a which_o plain_o prove_v that_o it_o be_v not_o the_o fume_n of_o the_o wine_n be_v the_o cause_n of_o the_o sleep_n because_o he_o be_v not_o at_o all_o sleepy_a when_o there_o must_v be_v more_o fume_n 27._o all_o allow_v that_o hot_a fume_n assault_v the_o brain_n cause_n frenzy_n if_o that_o be_v true_a than_o the_o fume_n of_o wine_n and_o opium_n which_o be_v both_o very_a hot_a must_v always_o do_v so_o but_o opium_n and_o wine_n also_o do_v often_o cause_v composure_n good_a humour_n sleep_v etc._n etc._n which_o be_v contrary_a to_o frenzy_n therefore_o they_o do_v not_o operate_v by_o fume_n 28._o if_o sleep_n say_v helmont_n the_o only_a man_n that_o i_o have_v read_v who_o be_v against_o vapour_n be_v cause_v by_o vapour_n ascend_v from_o the_o stomach_n to_o the_o head_n obstruct_v and_o intercept_n all_o the_o passage_n of_o sensation_n motion_n speech_n judgement_n etc._n etc._n as_o the_o school_n say_v than_o a_o disease_n will_v have_v be_v before_o the_o fall_n of_o adam_n because_o sleep_n will_v have_v be_v a_o disease_n that_o be_v a_o flatulent_a and_o vaporous_a palsy_n 29._o all_o allow_v vomitives_n and_o purger_n to_o operate_v by_o irritation_n or_o a_o grievous_a sensation_n of_o the_o membrane_n of_o the_o stomach_n why_o not_o wine_n cordial_n opium_n etc._n etc._n by_o a_o pleasant_a sensation_n cujus_fw-la est_fw-la dolour_n aut_fw-la gravamen_fw-la ejusdem_fw-la est_fw-la voluptas_fw-la and_o as_o a_o grievous_a sensation_n or_o pain_n cause_v melancholy_a depression_n of_o spirit_n fretfulness_n lassitude_n etc._n etc._n so_o a_o pleasant_a sensation_n cause_v comfort_n elevation_n of_o the_o spirit_n euphory_n etc._n etc._n but_o we_o have_v not_o clear_v the_o way_n sufficient_o for_o these_o matter_n yet_o which_o will_v in_o due_a time_n be_v solemn_o consider_v obj._n it_o may_v be_v say_v that_o both_o vomitives_n and_o purgative_n take_v some_o time_n before_o they_o operate_v unless_o a_o nausea_n upon_o aversion_n cause_v they_o to_o work_v soon_o for_o thing_n must_v have_v time_n to_o insinuate_v themselves_o or_o soak_v through_o the_o crusta_fw-la carnosa_fw-la of_o the_o stomach_n and_o afterward_o to_o affect_v its_o sensile_a coat_n which_o argue_v that_o wine_n and_o cordial_n which_o operate_v immediate_o do_v not_o operate_v that_o way_n but_o by_o fume_n or_o effuvium_n pass_v into_o the_o brain_n or_o blood_n answ._n i_o doubt_v indeed_o that_o this_o difference_n may_v be_v a_o occasion_n of_o refer_v the_o effect_n of_o cordial_n and_o those_o of_o emittick_n and_o cathartic_o to_o different_a cause_n but_o it_o be_v very_o strange_a that_o they_o shall_v go_v so_o far_o as_o the_o blood_n or_o brain_n to_o seek_v for_o the_o cause_n of_o the_o operation_n of_o cordial_n which_o operate_v in_o a_o moment_n and_o go_v no_o far_o than_o the_o stomach_n for_o the_o cause_n of_o the_o operation_n of_o vomatives_n and_o purgative_n which_o take_v more_o time_n to_o operate_v especial_o see_v the_o blood_n and_o brain_n have_v no_o sensation_n and_o that_o all_o sensitive_a comfort_n happen_v by_o that_o mean_n i_o think_v it_o be_v much_o more_o proper_a first_o to_o consider_v the_o immediate_a part_n upon_o which_o they_o insist_v when_o at_o stomach_n especial_o see_v it_o be_v so_o very_o sensible_a before_o we_o run_v rove_a i_o know_v not_o whither_o to_o seek_v for_o the_o cause_n of_o a_o thing_n that_o work_v please_v and_o comfort_v the_o stomach_n as_o soon_o as_o it_o be_v down_o i_o take_v myself_o run_v off_o the_o proper_a subject_a matter_n of_o this_o chapter_n and_o anticipate_v that_o of_o another_o therefore_o i_o will_v be_v short_a and_o deliver_v my_o opinion_n in_o this_o case_n by_o way_n of_o position_n with_o a_o familiar_a instance_n to_o illustrate_v it_o which_o may_v in_o some_o measure_n prepare_v you_o for_o the_o proof_n
of_o it_o and_o what_o be_v to_o be_v say_v thereof_o more_o at_o large_a hereafter_o i_o say_v then_o that_o hot_a spirituous_a cordial_n for_o such_o indeed_o all_o proper_a cordial_n be_v as_o brandy_n dr._n stephens_n water_n and_o suchlike_a have_v sulphureous_a particle_n so_o prepare_v and_o dispose_v towards_o heat_n or_o fire_n that_o they_o be_v as_o it_o be_v in_o potentia_fw-la proxima_fw-la or_o next_o disposition_n thereto_o be_v mighty_a apt_a to_o contract_v a_o heat_n as_o you_o find_v by_o spirit_n of_o wine_n or_o brandy_n keep_v the_o least_o time_n in_o a_o warm_a place_n or_o to_o come_v close_o to_o the_o matter_n in_o your_o mouth_n wherein_o be_v actuate_v by_o its_o heat_n they_o will_v as_o in_o a_o instant_n grow_v so_o hot_a and_o active_a that_o you_o can_v hardly_o bear_v they_o because_o particle_n of_o heat_n which_o penetrate_v any_o metal_n glass_n etc._n etc._n immediate_o as_o soon_o as_o apply_v thereto_o will_v much_o more_o easy_o and_o soon_o penetrate_v our_o soft_a part_n at_o mouth_n or_o the_o crusta_fw-la carnosa_fw-la at_o stomach_n and_o so_o reach_v the_o most_o sensile_a coat_n thereof_o please_v comfort_a and_o exciting_a the_o spiritus_fw-la insitos_fw-la as_o in_o a_o moment_n by_o their_o spirituous_a heat_n which_o we_o actual_o feel_v and_o sensible_o find_v to_o please_v and_o comfort_v the_o stomach_n but_o if_o some_o purge_v tincture_n have_v be_v put_v into_o the_o cordial_n or_o brandy_n this_o will_v not_o have_v soak_v through_o the_o crusta_fw-la carnosa_fw-la under_o some_o time_n and_o consequent_o not_o operate_v till_o it_o have_v this_o may_v be_v most_o manifest_o illustrate_v by_o some_o hot_a brandy_n or_o indeed_o any_o hot_a liquid_a put_v into_o a_o porous_a dish_n set_v upon_o one_o hand_n which_o present_o warm_v it_o but_o if_o the_o liquid_a be_v tinge_v with_o any_o thing_n that_o tincture_n will_v not_o reach_v the_o hand_n till_o the_o liquor_n which_o be_v its_o vehicle_n soak_v through_o which_o may_v be_v in_o a_o hour_n more_o or_o less_o according_a to_o the_o porosity_n of_o the_o wood_n which_o tincture_n be_v to_o be_v compare_v to_o the_o purgative_n at_o stomach_n hence_o it_o follow_v that_o all_o cordial_n shall_v be_v a_o spirituous_a liquid_a if_o intend_v for_o sudden_a refreshment_n which_o experience_n have_v teach_v and_o be_v give_v actual_o warm_v if_o a_o very_a nimble_a comfort_n be_v require_v though_o the_o great_a heat_n of_o the_o stomach_n above_o that_o of_o the_o mouth_n will_v general_o be_v sufficient_a thus_o may_v the_o stomach_n be_v please_v and_o comfort_v grieve_v and_o purge_v with_o the_o same_o draught_n but_o gracious_a providence_n have_v give_v the_o start_n to_o the_o cordial_n which_o immediate_o comfort_v we_o as_o a_o heater_n 30._o if_o opium_n operate_v by_o such_o fume_n it_o will_v at_o least_o in_o a_o liquid_a form_n begin_v its_o operation_n as_o soon_o as_o it_o be_v at_o stomach_n for_o it_o will_v begin_v to_o send_v up_o fume_n as_o soon_o as_o it_o begin_v to_o be_v warm_a which_o be_v present_o and_o be_v at_o a_o very_a considerable_a height_n of_o fume_v and_o consequent_o of_o operation_n in_o one_o minute_n which_o be_v about_o the_o space_n of_o seventy_o ordinary_a pulse_n but_o we_o do_v not_o find_v it_o begin_v to_o operate_v in_o that_o form_n under_o twenty_o thirty_o or_o forty_o minute_n which_o be_v much_o about_o the_o time_n that_o a_o more_o agreeable_a and_o not_o nauseated_a vomitive_a or_o purger_n begin_v to_o affect_v the_o sensile_a coat_n of_o the_o stomach_n and_o give_v intimation_n of_o their_o so_o do_v all_o which_o and_o the_o sense_n of_o pleasure_n that_o we_o actual_o then_o seel_v at_o stomach_n make_v it_o probable_a that_o it_o operate_v by_o affect_v the_o stomach_n pleasant_o and_o comfortable_o after_o the_o manner_n of_o generous_a wine_n as_o purger_n and_o vomatives_n do_v by_o affect_v it_o grievous_o all_o of_o they_o except_o the_o wine_n that_o please_v and_o comfort_v soon_o because_o of_o its_o particle_n of_o heat_n gain_v by_o fermentation_n operate_a much_o in_o the_o same_o time_n because_o they_o take_v like_o leisure_n to_o soak_v through_o the_o crusta_fw-la carnosa_fw-la to_o the_o sensile_a coat_n of_o the_o stomach_n 31._o all_o sensitive_a pleasure_n comfort_n etc._n etc._n be_v receive_v by_o the_o sense_n and_o though_o any_o part_n be_v some_o way_n benefit_v that_o have_v no_o sense_n no_o comfort_n will_v be_v perceive_v without_o perception_n none_o can_v say_v that_o he_o be_v comfort_v what_o fit_a part_n be_v there_o to_o be_v please_v and_o comfort_v by_o sensation_n than_o the_o stomach_n which_o have_v such_o exquisite_a sense_n that_o it_o can_v discern_v the_o vomitory_n particle_n in_o infusion_n of_o the_o grocus_n or_o regulus_n of_o antimony_n which_o no_o sensation_n but_o that_o at_o stomach_n can_v discern_v and_o so_o small_a that_o a_o thousand_o vomitory_n make_v thereof_o by_o infusion_n do_v not_o sensible_o diminish_v the_o grocus_n or_o regulus_n as_o to_o weight_n or_o bulk_n nor_o can_v i_o conceive_v where_o any_o sensible_a comfort_n can_v be_v perceive_v by_o a_o spoonful_n of_o cordial_n but_o at_o stomach_n where_o it_o actual_o be_v and_o upon_o who_o coat_n it_o immediate_o insist_o be_v it_o not_o there_o that_o we_o feel_v the_o comfort_n and_o where_o shall_v we_o find_v it_o but_o there_o what_o will_v the_o effluvium_n of_o a_o spoonful_n signify_v if_o mix_v with_o 100000_o time_n as_o much_o insensile_a blood_n and_o what_o part_n beside_o the_o stomach_n that_o the_o blood_n touch_v can_v be_v sensible_a of_o it_o so_o that_o if_o effluvium_n be_v grant_v it_o be_v thither_o they_o must_v return_v to_o cause_v any_o considerable_a pleasure_n or_o comfort_n but_o what_o need_v any_o reâ—urn_n of_o the_o inconsiderable_a effluvia_fw-la when_o the_o main_a body_n of_o the_o cordial_n yea_o all_z lie_v upon_o the_o stomach_n already_o i_o must_v forbear_v run_v into_o the_o business_n of_o other_o chapter_n have_v be_v tedious_a enough_o upon_o the_o subject_a of_o this_o and_o the_o rather_o because_o it_o be_v so_o general_a and_o so_o root_v a_o opinion_n in_o the_o mind_n of_o man_n in_o all_o age_n and_o in_o all_o sect_n of_o physician_n and_o natural_a philosopher_n that_o i_o can_v not_o say_v too_o much_o to_o endeavour_v to_o free_v the_o world_n from_o the_o slavery_n of_o such_o a_o imposition_n and_o the_o innumerable_a ill_a consequence_n of_o such_o a_o fundamental_a and_o overgrow_a error_n which_o certain_o must_v have_v be_v long_o since_o explode_v if_o ingenious_a man_n have_v first_o think_v and_o then_o speak_v free_o but_o the_o truth_n be_v there_o be_v many_o and_o great_a cause_n to_o the_o contrary_a as_o those_o intimate_v in_o the_o last_o paragraph_n and_o the_o mighty_a usefulness_n and_o ready_a officiousness_n of_o that_o opinion_n of_o fume_n to_o answer_v for_o all_o the_o more_o obscure_a and_o latent_fw-la cause_n of_o the_o malady_n and_o disaster_n of_o the_o brain_n and_o genus_fw-la nervosum_fw-la if_o any_o inquire_v or_o call_v for_o the_o cause_n of_o a_o vertigo_n the_o physician_n answer_v fume_n of_o epilepsy_n it_o be_v answer_v fume_n of_o scotomy_n it_o be_v fume_n of_o headache_n migraine_n coma_n caros_n lethargy_n etc._n etc._n it_o be_v fume_n of_o hysterick_n fit_n convulsion_n spasm_n cramp_n etc._n etc._n it_o be_v fume_n nay_o they_o answer_v as_o cause_n to_o all_o distillation_n catarrh_n epiphora_n or_o weep_v eye_n and_o all_o even_o ordinary_a tear_n all_o which_o they_o say_v be_v only_o these_o fume_n turn_v into_o water_n by_o the_o coldness_n of_o the_o brain_n as_o they_o be_v in_o a_o still_o or_o alembick_a so_o hot_a fume_n account_v for_o frenzy_n delirium_n rave_n etc._n etc._n so_o that_o however_o other_o head_n be_v the_o physician_n be_v be_v stuff_v therewith_o and_o all_o meteor_n of_o the_o microcosm_n upper_a region_n whether_o hot_a or_o cold_a be_v as_o those_o in_o the_o macrocosm_n form_v out_o of_o fume_n as_o he_o imagine_v thus_o you_o see_v all_o the_o opinion_n and_o hypothesise_n that_o have_v be_v concern_v the_o operation_n of_o opium_n to_o be_v most_o absurd_a and_o direct_o contrary_a to_o all_o sense_n reason_n and_o experience_n chap._n xi_o opium_n do_v not_o diminish_v or_o disable_v the_o spirit_n by_o any_o mean_n whatsoever_o have_v sufficient_o demonstrate_v that_o opium_n can_v diminish_v or_o disable_v the_o spirit_n by_o the_o cold_a quality_n of_o the_o ancient_n or_o fume_n of_o the_o modern_n and_o that_o neither_o of_o they_o have_v as_o much_o as_o any_o be_v i_o shall_v now_o add_v that_o opium_n do_v not_o diminish_v or_o disable_v the_o spirit_n by_o any_o other_o mean_n whatsoever_o i_o will_v not_o be_v mistake_v when_o i_o say_v that_o opium_n do_v not_o diminish_v or_o disable_v
the_o spirit_n by_o any_o mean_n for_o there_o be_v nothing_o so_o good_a in_o nature_n but_o will_v do_v it_o if_o use_v undue_o or_o immoderate_o as_o wine_n bread_n milk_n honey_n sugar_n beer_n etc._n etc._n in_o excess_n for_o i_o intend_v that_o it_o do_v not_o do_v it_o when_o due_o and_o moderate_o use_v 1._o that_o which_o refresh_v the_o weary_a and_o high_o prevent_v weariness_n must_v add_v to_o or_o excite_v the_o spirit_n which_o be_v direct_o contrary_a to_o diminish_v or_o disable_n they_o but_o opium_n do_v in_o a_o most_o eminent_a manner_n refresh_v the_o weary_v and_o prevent_v weariness_n therefore_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n some_o have_v be_v so_o silly_a and_o inadvertent_n as_o to_o object_n that_o it_o refresh_v the_o weary_a only_o by_o sleep_n it_o be_v matter_n of_o fact_n that_o it_o refresh_v they_o whether_o they_o sleep_v or_o no_o and_o that_o without_o fail_v as_o often_o as_o it_o be_v use_v in_o that_o case_n other_o that_o be_v no_o wise_a have_v say_v that_o it_o only_o take_v off_o the_o sense_n of_o weariness_n by_o stupify_a which_o happen_v by_o the_o diminish_n or_o disable_n of_o the_o animal_n spirit_n bare_a insensibleness_n can_v enable_v the_o spirit_n to_o labour_n with_o eminent_a briskness_n and_o alacrity_n as_o man_n most_o certain_o do_v after_o opium_n be_v take_v be_v fine_o enliven_v and_o invigorate_v as_o with_o generous_a wine_n if_o they_o do_v not_o know_v this_o to_o be_v true_a let_v they_o for_o shame_n hold_v their_o tongue_n till_o they_o know_v matter_n of_o fact_n which_o if_o they_o will_v not_o they_o proclaim_v themselves_o to_o be_v idle_a and_o impertinent_a babbler_n but_o if_o they_o will_v patient_o and_o wise_o abstain_v argue_v till_o they_o be_v satisfy_v as_o to_o matter_n of_o fact_n then_o will_v they_o be_v past_a opinion_n and_o hypothesis_n in_o that_o case_n for_o they_o will_v have_v sensible_a and_o certain_a knowledge_n of_o the_o contrary_a and_o the_o truth_n of_o what_o i_o say_v which_o will_v end_v all_o controversy_n and_o precarious_a squabble_n upon_o false_a supposition_n as_o the_o manner_n be_v that_o can_v lead_v they_o to_o what_o be_v right_o but_o by_o mere_a chance_n and_o never_o to_o a_o true_a knowledge_n that_o they_o be_v in_o the_o right_n which_o make_v it_o none_o in_o effect_n for_o they_o can_v do_v nothing_o with_o assurance_n but_o only_o suppose_v and_o hope_v they_o be_v in_o the_o right_n when_o they_o be_v as_o much_o out_o to_o their_o patient_n sorrow_n as_o physician_n have_v be_v in_o the_o cold_a quality_n and_o fume_n of_o opium_n it_o be_v true_a that_o a_o grain_n or_o two_o of_o opium_n will_n if_o a_o man_n compose_v himself_o sit_v or_o lie_v still_o cause_n a_o sleepiness_n equal_a to_o that_o cause_v by_o spend_v the_o spirit_n by_o a_o day_n be_v labour_n but_o spend_v of_o the_o spirit_n be_v not_o the_o only_a no_o nor_o best_a proportion_v or_o more_o adequate_a cause_n thereof_o as_o i_o have_v show_v if_o loss_n of_o spirit_n be_v the_o adequate_a cause_n of_o sleep_n how_o shall_v good_a and_o generous_a wine_n cause_n sleepiness_n after_o that_o eminent_a rate_n as_o it_o do_v in_o most_o people_n how_o shall_v the_o most_o please_a music_n incline_v such_o as_o lie_v or_o sit_v still_o to_o sleep_v but_o if_o one_o dance_n thereto_o it_o make_v he_o more_o lively_a and_o brisk_a than_o ordinary_a the_o like_a exact_o do_v wine_n and_o opium_n if_o man_n lie_v or_o sit_v still_o but_o otherwise_o they_o make_v they_o much_o more_o brisk_a and_o lively_a and_o able_a to_o undergo_v labour_n action_n etc._n etc._n which_o note_n that_o you_o may_v not_o any_o more_o wonder_n that_o enlivener_n and_o exciter_n of_o the_o spirit_n do_v cause_n sleep_v as_o well_o as_o diminisher_n thereof_o and_o observe_v that_o they_o be_v all_o please_a thing_n as_o music_n wine_n and_o opium_n which_o cause_n pleasant_a dream_n pleasant_a watch_n pleasant_a humour_n etc._n etc._n expect_v more_o of_o this_o matter_n in_o the_o follow_a chapter_n and_o all_o by_o degree_n according_a as_o i_o judge_v the_o prejudice_v world_n will_v bear_v thing_n for_o a_o great_a paradox_n how_o true_a soever_o must_v not_o be_v abrupt_o obtrude_v but_o gentle_o and_o gradual_o usher_v in_o by_o insinuate_v reason_v otherwise_o it_o will_v be_v entertain_v like_o a_o rude_a stranger_n that_o contradict_v a_o multitude_n in_o fashion_n and_o custom_n that_o they_o have_v always_o use_v and_o judge_v to_o be_v the_o very_o best_o however_o unblamable_a consider_v that_o if_o opium_n diminish_v or_o disable_v the_o spirit_n proportionable_a to_o the_o sleepiness_n that_o it_o cause_n as_o a_o hard_a day_n be_v labour_n do_v then_o if_o opium_n be_v give_v a_o man_n after_o a_o hard_a day_n be_v labour_n it_o will_v be_v as_o it_o be_v add_v another_o hard_a day_n be_v labour_v to_o cure_v it_o the_o day_n be_v labour_n and_o opium_n impair_n the_o spirit_n alike_o think_v what_o a_o miserable_a condition_n the_o poor_a man_n will_v be_v in_o especial_o if_o sleep_n do_v not_o make_v he_o some_o amends_o it_o will_v be_v such_o as_o be_v utter_o intolerable_a but_o so_o far_o be_v opium_n from_o any_o such_o effect_n that_o it_o refresh_v he_o though_o he_o sleep_v not_o at_o all_o after_o the_o hard_a day_n be_v labour_n and_o not_o only_o so_o but_o will_v enable_v he_o to_o work_v all_o the_o follow_a night_n with_o great_a alacrity_n if_o need_n require_v it_o what_o a_o condition_n will_v those_o be_v in_o who_o take_v a_o drachm_n of_o it_o twice_o a_o day_n for_o 10_o 20_o or_o 30_o year_n nay_o how_o can_v any_o possible_o do_v it_o for_o half_a 10_o day_n if_o a_o grain_n or_o two_o destroy_v the_o spirit_n so_o much_o as_o to_o cause_v sleepiness_n thereby_o as_o hard_a labour_n do_v which_o they_o must_v allow_v that_o assert_v it_o cause_n sleep_v by_o diminish_v or_o disable_n the_o spirit_n but_o some_o may_v say_v though_o very_o inconsiderate_o that_o it_o only_o disable_v they_o for_o the_o time_n of_o its_o operation_n that_o be_v strange_a indeed_o consider_v that_o even_o during_o that_o time_n they_o be_v most_o enable_v to_o work_n or_o labour_n though_o tire_v before_o and_o that_o it_o 2._o cause_n comfort_n refreshment_n ovation_n of_o the_o spirit_n all_o the_o time_n of_o its_o operation_n as_o wine_n moderate_o take_v do_v especial_o if_o people_n keep_v themselves_o in_o action_n labour_n etc._n etc._n otherwise_o indeed_o they_o may_v fall_v asleep_a upon_o the_o comfortable_a satisfaction_n contentation_n of_o mind_n and_o acquiescence_n of_o spirit_n that_o it_o occasion_n as_o wine_n do_v 3._o the_o first_o effect_n that_o we_o find_v of_o opium_n which_o may_v therefore_o probable_o be_v a_o very_a lead_n fundamental_a and_o significant_a effect_n be_v that_o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o incline_v he_o to_o sleep_n if_o not_o it_o make_v he_o gay_a good_a humour_a brave_a etc._n etc._n it_o be_v a_o pleasure_n so_o sweet_a and_o delicious_a that_o though_o i_o endeavour_v to_o express_v it_o by_o the_o ovation_n of_o the_o spirit_n upon_o joy_n a_o good_a genius_n inform_v a_o man_n or_o the_o helmâ—sians_n archaeus_n in_o his_o best_a humour_n or_o a_o continual_a vâ—real_a pleasure_n wine_n drink_v ad_fw-la hilaritatem_fw-la etc._n etc._n yet_o i_o doubt_v all_o my_o way_n of_o express_v it_o do_v come_v short_a of_o the_o charm_a complacency_n that_o it_o cause_n therefore_o if_o wine_n music_n a_o good_a meal_n agreeable_a frication_n of_o the_o head_n or_o back_o the_o sound_n of_o water_n etc._n etc._n do_v incline_v we_o to_o sleep_v by_o the_o pleasure_n thereof_o which_o lull_v and_o soothe_v we_o to_o it_o as_o be_v most_o certain_a if_o we_o sit_v or_o lie_v still_o much_o more_o must_v the_o high_a charm_n of_o opium_n cause_n it_o that_o it_o be_v a_o pleasure_n that_o affect_v by_o one_o of_o our_o sense_n namely_o by_o feel_v be_v indisputable_a for_o it_o be_v not_o a_o pleasure_n of_o the_o eye_n nose_n tongue_n or_o ear_n and_o it_o must_v be_v sensitive_a because_o cause_v by_o matter_n and_o that_o opium_n have_v doubtless_o the_o like_a effect_n upon_o brute_n who_o have_v no_o other_o pleasure_n but_o what_o be_v sensitive_a that_o it_o be_v at_o stomach_n be_v also_o evident_a where_o we_o can_v be_v please_v only_o by_o the_o sense_n of_o feel_v that_o it_o be_v involuntary_a and_o please_v we_o whether_o we_o will_v or_o no_o and_o that_o the_o same_o particle_n excite_v venery_n itch_a etc._n etc._n now_o all_o the_o sense_n especial_o feel_v and_o particular_o that_o at_o stomach_n be_v give_v we_o for_o
watch_n and_o sentinel_n to_o discover_v and_o give_v notice_n of_o what_o be_v or_o be_v not_o good_a and_o agreeable_a to_o our_o animal_n nature_n that_o upon_o notice_n of_o what_o be_v good_a and_o agreeable_a pleasure_n comfort_n satisfaction_n etc._n etc._n be_v conceive_v otherwise_o displeasure_n discomfort_n and_o dissatisfaction_n what_o diminish_v or_o disable_v our_o spirit_n do_v we_o the_o great_a evil_n that_o can_v be_v and_o consequent_o sensation_n will_v according_a to_o its_o office_n give_v we_o such_o notice_n thereof_o as_o will_v cause_v displeasure_n etc._n etc._n otherwise_o these_o sentinel_n that_o god_n and_o nature_n have_v appoint_v for_o faithful_a notice_n will_v instead_o of_o trusty_a service_n which_o be_v the_o end_n they_o be_v make_v for_o deceive_v we_o and_o consequent_o do_v we_o mischief_n rather_o than_o good_a which_o be_v very_o profane_a if_o not_o blasphemous_a to_o assert_v as_o be_v high_o abusive_a of_o god_n goodness_n and_o wisdom_n to_o make_v thing_n in_o nature_n that_o will_v not_o only_o not_o answer_n but_o act_n quite_o contrary_a to_o their_o end_n it_o follow_v then_o that_o what_o cause_v such_o a_o mighty_a agreeable_a and_o pleasant_a sensation_n at_o stomach_n which_o be_v the_o great_a and_o most_o accurate_a judge_n of_o what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n can_v be_v destructive_a or_o disable_n of_o its_o spirit_n which_o be_v the_o most_o excellent_a and_o useful_a thing_n that_o belong_v thereto_o therefore_o opium_n which_o so_o mighty_o recommend_v itself_o to_o please_v and_o comfort_v the_o great_a judge_n that_o god_n have_v give_v to_o a_o sensible_a creature_n to_o discern_v what_o be_v good_a and_o evil_a for_o it_o can_v diminish_v or_o disable_v our_o spirit_n one_o may_v say_v what_o i_o dare_v not_o that_o the_o sensation_n at_o stomach_n may_v deceive_v we_o we_o may_v deceive_v ourselves_o and_o say_v so_o when_o that_o which_o please_v the_o stomach_n do_v not_o please_v our_o pervert_v imagination_n which_o make_v no_o argument_n let_v we_o therefore_o consider_v thing_n where_o there_o be_v no_o such_o vain_a imagination_n to_o contradict_v the_o good_a end_n of_o nature_n if_o the_o stomach_n and_o sense_n in_o a_o brute_n or_o mere_a animal_n which_o have_v no_o other_o mean_n to_o judge_n of_o what_o be_v good_a or_o evil_n for_o it_o shall_v not_o judge_v aright_o all_o the_o animal_n in_o the_o whole_a world_n will_v soon_o perish_v it_o be_v the_o vain_a opinion_n of_o man_n that_o persuade_v they_o that_o thing_n be_v cold_a when_o hot_a etc._n etc._n as_o in_o the_o case_n of_o opium_n when_o the_o sense_n true_o inform_v that_o it_o be_v hot_a if_o you_o will_v stand_v to_o your_o imagination_n and_o supposition_n for_o such_o all_o must_v be_v without_o the_o information_n of_o sense_n against_o the_o dictate_v of_o sensation_n you_o must_v inevitable_o err_v but_o one_o may_v say_v be_v the_o sense_n at_o stomach_n such_o a_o infallible_a guide_n always_o i_o believe_v it_o will_v be_v very_o hard_a to_o give_v many_o instance_n to_o the_o contrary_a and_o prove_v it_o well_o however_o if_o we_o do_v or_o may_v allow_v something_o of_o this_o kind_a to_o a_o pervert_v stomach_n at_o certain_a time_n to_o avoid_v a_o squabble_n about_o it_o it_o be_v never_o to_o be_v allow_v that_o all_o the_o stomach_n in_o the_o whole_a world_n shall_v be_v please_v with_o one_o and_o the_o same_o thing_n at_o all_o time_n and_o yet_o that_o this_o thing_n shall_v be_v so_o high_o pernicious_a to_o the_o animal_n as_o to_o diminish_v or_o disable_v its_o spirit_n then_o indeed_o it_o will_v follow_v that_o the_o most_o exquisite_a sense_n at_o stomach_n to_o discern_v what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n be_v absolute_o in_o vain_a which_o no_o man_n of_o reason_n that_o have_v any_o apprehension_n of_o the_o wisdom_n of_o god_n and_o nature_n can_v assert_v 3._o what_o be_v more_o notorious_a than_o that_o pleasure_n or_o be_v please_v raise_v and_o displeasure_n or_o be_v grieve_v depress_n the_o spirit_n be_v not_o all_o people_n pleasant_a gay_a and_o good_a humour_a brisk_a prompt_a etc._n etc._n when_o please_v do_v not_o man_n travel_v or_o labour_n with_o more_o ease_n in_o pleasant_a company_n etc._n etc._n but_o of_o these_o matter_n and_o the_o reason_n thereof_o more_o in_o the_o follow_a chapter_n 4._o how_o can_v opium_n that_o revive_v people_n when_o they_o be_v so_o dispirited_a that_o they_o be_v even_o almost_o die_v as_o when_o opium_n be_v want_v by_o such_o as_o use_v to_o take_v it_o in_o deliquiâ—ms_n and_o agony_n from_o paiâ—_n etc._n etc._n diminish_v or_o disable_v the_o spirit_n it_o be_v plain_a contradiction_n to_o say_v that_o it_o shall_v next_o to_o opium_n nothing_o revive_v people_n in_o such_o case_n better_o than_o wine_n and_o those_o thing_n that_o produce_v the_o same_o or_o like_a effect_n have_v like_o nature_n and_o who_o can_v say_v that_o wine_n that_o be_v make_v to_o glad_a the_o heart_n of_o man_n diminish_v or_o disable_v the_o spirit_n or_o that_o opium_n which_o produce_v all_o the_o sprightly_a enliven_a and_o encourage_v effect_n of_o generous_a wine_n in_o a_o more_o eminent_a manner_n than_o wine_n and_o in_o the_o 10000th_o part_n of_o its_o quantity_n and_o for_o a_o long_a time_n than_o wine_n cause_v they_o shall_v diminish_v or_o disable_v the_o spirit_n for_o instance_n wine_n and_o opium_n in_o a_o due_a quantity_n but_o opium_n in_o a_o far_o less_o quantity_n as_o be_v say_v cause_v a_o pleasant_a gay_a and_o good_a humour_n courage_n bravery_n magnanimity_n promptitude_n in_o business_n expediteness_n in_o management_n serenity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n fatigue_n etc._n etc._n both_o take_v away_o sadness_n grief_n melancholy_n fear_v depression_n of_o spirit_n etc._n etc._n both_o cause_n promptitude_n to_o venery_n sine_fw-la cerere_fw-la &_o baccho_fw-la friget_fw-la venus_n so_o wine_n and_o opium_n prevent_v and_o cure_v cold_a open_v the_o pore_n promote_v perspiration_n and_o sweat_n especial_o the_o follow_a morning_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v of_o opium_n and_o be_v notorious_a as_o to_o wine_n both_o cause_n sleep_n and_o take_v away_o the_o sense_n of_o pain_n and_o require_v a_o great_a dose_n than_o ordinary_a in_o proportion_n to_o the_o pain_n both_o take_v off_o shivering_n from_o fear_n cold_a or_o ague_n fit_n and_o cause_n mirth_n contentation_n and_o acquiescence_n dryness_n of_o the_o mouth_n thirst_v a_o sense_n of_o heat_n within_o we_o a_o dream_v condition_n pleasant_a dream_n if_o the_o quantity_n of_o wine_n be_v not_o grievous_a by_o its_o heat_n load_n etc._n etc._n nocturnal_a pollution_n and_o in_o some_o constitution_n both_o cause_n vigilancy_n but_o wine_n and_o opium_n cause_v that_o more_o rare_o than_o sleep_n both_o stop_n and_o cause_n vomit_v if_o they_o stay_v too_o long_o at_o stomach_n both_o moderate_a hunger_n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d and_o be_v good_a in_o a_o canine_a appetite_n both_o cause_n swim_v in_o the_o head_n etc._n etc._n so_o both_o in_o a_o excessive_a do_v do_v cause_n at_o first_o mirth_n and_o afterward_o a_o kind_n of_o drunken_a soper_n in_o some_o in_o other_o fury_n or_o madness_n sardonick_a laughter_n and_o weight_n at_o stomach_n vomit_n hiccough_n great_a heat_n at_o stomach_n debility_n and_o laxity_n of_o all_o part_n falter_v of_o the_o tongue_n scotomy_n and_o darkness_n of_o the_o eye_n vertigo_n laxity_n of_o the_o cornea_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la deadness_n of_o the_o eye_n to_o the_o view_n loss_n of_o memory_n venereal_a fury_n a_o high_a colour_n profuse_a sweat_v purge_v sometime_o alienation_n of_o the_o mind_n loss_n of_o memory_n and_o last_o great_a or_o lesser_a effect_n according_a to_o the_o do_v constitution_n etc._n etc._n so_o a_o long_a and_o lavish_a use_n of_o both_o cause_n a_o dull_a and_o moapish_a disposition_n dropsy_n fall_v of_o humour_n upon_o weaken_v part_n a_o sleepy_a disposition_n want_v of_o appetite_n weakness_n of_o digestion_n aptitude_n to_o sterility_n and_o abortion_n early_a decrepiteness_n stoop_v in_o the_o back_n tremble_v of_o the_o hand_n weakness_n of_o memory_n shortness_n of_o life_n difficulty_n and_o danger_n in_o sudden_o leave_v they_o off_o revive_v such_o as_o sink_v for_o want_n of_o either_o and_o supply_v the_o want_n of_o each_o other_o how_o can_v any_o have_v the_o face_n to_o say_v that_o a_o thing_n which_o agree_v so_o with_o generous_a wine_n in_o effect_n can_v be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n the_o mischief_n of_o excessive_a dose_n and_o lavish_a use_n of_o either_o be_v no_o argument_n against_o their_o inspirit_a nature_n if_o it_o be_v than_o wine_n be_v no_o cordial_n though_o make_v to_o glad_a the_o heart_n
of_o man_n because_o of_o its_o ill_a effect_n lavish_o use_v therefore_o none_o can_v argue_v from_o that_o that_o opium_n diminish_v or_o disable_v the_o spirit_n any_o more_o than_o wine_n or_o bread_n do_v a_o surfeit_n of_o which_o be_v most_o dangerous_a omnis_fw-la repletio_fw-la mala_fw-la panis_n vero_fw-la pessima_fw-la &_o corruptio_fw-la optimi_fw-la est_fw-la pessima_fw-la that_o be_v all_o repletion_n be_v bad_a but_o that_o of_o bread_n be_v the_o worst_a and_o the_o corruption_n of_o the_o best_a be_v the_o worst_a the_o short_a be_v this_o wine_n and_o opium_n agree_v in_o all_o their_o effect_n save_v such_o as_o be_v consequence_n of_o their_o different_a accident_n as_o the_o quantity_n of_o wine_n that_o must_v be_v use_v to_o cause_v the_o same_o effect_n with_o a_o little_a opium_n and_o wine_n have_v be_v ferment_v and_o opium_n as_o may_v be_v show_v have_v some_o crude_a and_o viscid_a rosin_n in_o it_o which_o sometime_o stick_v to_o the_o crusta_fw-la carnosa_fw-la etc._n etc._n of_o the_o stomach_n whence_o it_o happen_v that_o wine_n load_v one_o more_o heat_v more_o and_o be_v more_o troublesome_a upon_o those_o account_n and_o that_o opium_n offend_v the_o stomach_n often_o even_o in_o a_o moderate_a do_v cause_v vomit_n hiccough_n anxiety_n distress_n at_o stomach_n deliquium_n etc._n etc._n because_o of_o the_o indigestible_a rosin_n stick_v to_o the_o side_n of_o the_o most_o sensile_a stomach_n as_o i_o shall_v far_o prove_v hereafter_o by_o god_n help_n show_v very_o easy_a way_n and_o mean_n to_o separate_v that_o rosin_n and_o so_o make_v it_o as_o safe_a and_o less_o troublesome_a as_o it_o be_v more_o effectual_a than_o wine_n opium_n can_v diminish_v or_o disable_v the_o spirit_n because_o as_o have_v be_v prove_v it_o send_v no_o part_n fume_v or_o effluvium_fw-la to_o the_o brain_n or_o animal_n spirit_n to_o cause_v such_o bad_a effect_n while_o it_o be_v at_o stomach_n yet_o do_v it_o produce_v they_o while_o it_o be_v there_o for_o as_o the_o vaporarians_n themselves_o and_o indeed_o all_o man_n allow_v there_o can_v be_v no_o destruction_n without_o contact_n sanctorius_n do_v well_o and_o true_o observe_v by_o the_o help_n of_o his_o static_o that_o nothing_o cause_v liberal_a perspiration_n but_o it_o raise_v the_o spirit_n it_o be_v most_o certain_a that_o nothing_o in_o nature_n open_v the_o pore_n and_o cause_n perspiration_n more_o than_o opium_n therefore_o nothing_o shall_v according_a to_o his_o observation_n elevate_v the_o spirit_n more_o and_z indeed_o nothing_o do_v as_o appear_v by_o all_o that_o have_v be_v say_v and_o will_v yet_o more_o plain_o appear_v loss_n of_o memory_n by_o opium_n as_o some_o argue_v be_v not_o so_o much_o a_o loss_n of_o spirit_n as_o lanity_n of_o the_o brain_n for_o people_n in_o drink_n do_v not_o want_v spirit_n but_o there_o be_v a_o great_a relaxation_n of_o the_o brain_n and_o its_o membrane_n and_o of_o the_o whole_a jenus_fw-la 〈◊〉_d which_o relaxation_n cause_v a_o soft_a loose_a and_o labile_fw-la brain_n that_o like_o liquid_a thing_n retain_v no_o impression_n beside_o that_o i_o shall_v god_n will_v show_v you_o hereafter_o that_o impression_n can_v be_v so_o well_o make_v upon_o the_o sensitive_a soul_n by_o the_o animal_n spirit_n upon_o relaxation_n of_o the_o sensible_a part_n as_o in_o sleep_n etc._n etc._n for_o a_o very_a plain_a mechanical_a reason_n to_o be_v show_v in_o due_a time_n thus_o have_v i_o by_o the_o assistance_n of_o its_o maker_n who_o best_o know_v it_o clear_v opium_n from_o the_o false_a aspersion_n of_o a_o extreme_a cold_a quality_n and_o parcotick_a fume_n both_o which_o be_v common_o call_v venomous_a fatal_a and_o by_o all_o the_o ill_a name_n imaginable_a but_o as_o good_a luck_n be_v they_o abuse_v nothing_o because_o it_o be_v manifest_a that_o there_o be_v no_o such_o thing_n nor_o have_v it_o any_o quality_n by_o which_o it_o diminish_v or_o disable_v the_o spirit_n as_o be_v most_o evident_a from_o the_o premise_n so_o that_o all_o that_o have_v be_v say_v of_o opium_n by_o way_n of_o hypothesis_n to_o explain_v its_o effect_n depend_v upon_o its_o diminish_n or_o disable_n the_o spirit_n by_o a_o cold_a quality_n or_o fume_n be_v come_v to_o nothing_o i_o wish_v it_o have_v be_v as_o innocent_a chap._n xii_o show_v what_o must_v be_v the_o true_a cause_n of_o the_o operation_n of_o opium_n all_o the_o general_a foundation_n upon_o which_o author_n either_o ancient_a or_o modern_a erect_v their_o several_a hypothesise_n concern_v the_o operation_n of_o opium_n have_v as_o manifest_o appear_v no_o real_a existence_n what_o enchant_a castle_n in_o the_o air_n or_o vain_a phantasm_n must_v their_o structure_n be_v and_o how_o like_a delude_a wizzard_n must_v they_o appear_v while_o they_o seem_v to_o take_v high_a flight_n and_o glorious_a prospect_n of_o cause_n that_o have_v no_o reality_n thus_o be_o i_o leave_v utter_o destitute_a of_o either_o foundation_n or_o model_n unless_o i_o find_v out_o that_o and_o frame_v this_o which_o i_o hope_v may_v be_v easy_o do_v because_o the_o cloudy_a supposition_n of_o vapour_n have_v vanish_v away_o there_o now_o remain_v but_o two_o way_n by_o which_o a_o internal_a medicament_n can_v operate_v viz._n 1._o as_o a_o alterative_a of_o the_o blood_n etc._n etc._n or_o 2._o as_o affect_v the_o sense_n of_o feel_v either_o grievous_o as_o vomit_n purger_n etc._n etc._n or_o pleas_o as_o cordial_n generous_a wine_n titillate_v amphrodisiack_n comfortable_a warmth_n anodynes_n and_o such_o like_a that_o please_v the_o nerve_n and_o membrane_n which_o way_n of_o operate_n be_v too_o little_o observe_v by_o physician_n though_o they_o take_v great_a notice_n of_o the_o operation_n of_o thing_n by_o grievous_a sensation_n as_o irritative_n to_o vomit_n purge_v salivate_a etc._n etc._n by_o their_o acrimony_n whereas_o the_o pleaser_n of_o sensation_n which_o must_v as_o contrary_n have_v contrary_a operation_n be_v little_o regard_v or_o think_v of_o 1._o opium_n do_v not_o operate_v as_o a_o alterative_a of_o the_o blood_n etc._n etc._n first_o because_o it_o operate_v while_o it_o be_v at_o stomach_n or_o at_o least_o before_o it_o arrive_v at_o the_o blood_n which_o manifest_o appear_v several_a way_n as_o 1._o because_o it_o often_o operate_v in_o a_o liquid_a form_n in_o few_o minute_n and_o very_o common_o in_o a_o quarter_n of_o a_o hour_n in_o which_o time_n it_o must_v be_v at_o stomach_n or_o at_o least_o far_o from_o arrive_v at_o the_o blood_n 2._o because_o it_o have_v be_v very_o often_o vomit_v up_o after_o it_o have_v operate_v and_o produce_v its_o usual_a effect_n for_o 1_o 2_o 3_o 4_o 5_o 6_o 8_o 10_o and_o sometime_o more_o hour_n as_o evident_o appear_v by_o the_o smell_n colour_n taste_v etc._n etc._n of_o what_o be_v vomit_v and_o by_o its_o operation_n cease_v after_o such_o vomit_v of_o which_o common_a experience_n and_o author_n do_v inform_v we_o see_v helmont_n ius_n duumvir_fw-la 62._o where_o he_o tell_v of_o opium_n operate_a at_o night_n and_o vomit_v up_o next_o morning_n 3._o it_o be_v bare_a cause_v vomit_v after_o it_o have_v operate_v for_o a_o good_a while_n be_v of_o itself_o though_o its_o taste_n smell_v etc._n etc._n do_v not_o discover_v it_o a_o infallible_a argument_n of_o its_o operate_n while_o it_o be_v at_o stomach_n for_o it_o be_v against_o all_o reason_n to_o imagine_v that_o thing_n shall_v irritate_fw-la it_o to_o vomit_n after_o they_o be_v go_v into_o the_o blood_n and_o not_o do_v it_o while_o they_o be_v in_o the_o stomach_n itself_o as_o all_o vomitory_n do_v the_o reason_n why_o it_o stay_v so_o long_o at_o stomach_n be_v 1._o it_o be_v indigestibleness_n which_o plain_o appear_v by_o stool_n urine_n and_o sweat_v smell_v of_o it_o when_o take_v in_o any_o considerable_a quantity_n all_o the_o coction_n digestion_n circulation_n etc._n etc._n that_o it_o pass_v in_o the_o body_n signify_v very_o little_a to_o it_o which_o its_o cause_v itch_n in_o the_o skin_n and_o affect_v the_o venereal_a membrane_n after_o its_o pass_v the_o blood_n do_v also_o argue_v 2._o the_o clamminess_n of_o its_o resinous_a part_n stick_v to_o the_o stomach_n cause_n as_o i_o shall_v plain_o prove_v hereafter_o its_o long_a stay_n in_o it_o for_o if_o the_o rosin_n be_v separate_v from_o it_o it_o will_v not_o then_o make_v such_o a_o long_a stay_n at_o stomach_n as_o i_o have_v often_o experience_v 4._o we_o actual_o feel_v it_o cause_v a_o sense_n of_o pleasure_n at_o stomach_n during_o its_o operation_n therefore_o it_o be_v then_o in_o it_o 5._o it_o have_v be_v carry_v off_o by_o stool_n after_o it_o have_v produce_v its_o usual_a effect_n therefore_o it_o operate_v before_o it_o arrive_v at_o the_o blood_n 6._o all_o observer_n do_v allow_v that_o opium_n operate_v while_o it_o be_v at_o stomach_n
preparatory_a discourse_n about_o sensation_n pleasure_n etc._n etc._n in_o the_o follow_a chapter_n you_o may_v sometime_o wonder_v what_o i_o will_v be_v at_o because_o you_o may_v not_o perceive_v the_o drift_n yet_o do_v they_o require_v your_o attention_n as_o be_v the_o foundation_n of_o all_o that_o be_v to_o follow_v which_o you_o will_v plain_o perceive_v afterward_o when_o i_o hope_v you_o will_v have_v good_a satisfaction_n for_o your_o patient_a and_o attentive_a perusal_n of_o the_o two_o follow_a chapter_n chap_n xiii_o of_o the_o oeconomy_n of_o sensation_n as_o far_o at_o least_o as_o it_o concern_v our_o present_a purpose_n when_o i_o have_v write_v this_o tract_n thus_o far_o i_o judge_v it_o best_o first_o to_o publish_v that_o of_o animal_n mechanism_n because_o it_o contain_v those_o principle_n that_o will_v explain_v the_o matter_n of_o opium_n therefore_o lay_v this_o aside_o i_o apply_v myself_o to_o that_o but_o a_o new_a art_n right_o to_o spell_n write_v and_o sweeten_v all_o language_n that_o i_o since_o call_v phonography_n come_v into_o my_o mind_n and_o think_v it_o may_v be_v very_o useful_a and_o likely_a to_o lie_v for_o ever_o in_o darkness_n as_o it_o have_v always_o be_v unless_o i_o undertake_v the_o drudgery_n i_o set_v myself_o to_o it_o which_o take_v up_o more_o time_n than_o i_o imagine_v have_v to_o this_o day_n hinder_v the_o finish_n of_o that_o tract_n of_o animal_n mechanism_n which_o i_o now_o much_o want_n as_o be_v intimate_v therefore_o because_o i_o resolve_v to_o publish_v this_o that_o be_v so_o long_o since_o promise_v i_o be_o now_o force_v for_o want_v of_o that_o book_n to_o premise_v here_o some_o thing_n concern_v the_o oeconomy_n of_o sensation_n and_o the_o nature_n of_o sensitive_a pleasure_n in_o order_n to_o explicate_v the_o effect_n of_o opium_n which_o may_v have_v be_v spare_v if_o that_o of_o animal_n mechanism_n have_v be_v publish_v consider_v that_o opium_n must_v as_o be_v show_v operate_v by_o please_v the_o sense_n of_o feel_v it_o will_v be_v requisite_a to_o consider_v 1._o the_o oeconomy_n of_o sensation_n as_o far_o as_o it_o concern_v the_o present_a purpose_n for_o which_o this_o chapter_n be_v design_v 2._o the_o nature_n of_o sensitive_a pleasure_n and_o its_o effect_n upon_o the_o sensitive_a soul_n and_o body_n which_o be_v to_o be_v the_o subject_a of_o the_o follow_a chapter_n five_o thing_n main_o concern_v the_o oeconomy_n of_o sensation_n 1._o the_o object_n 2._o the_o external_a medium_fw-la 3._o the_o organ_n of_o sensation_n 4._o the_o animal_n spirit_n or_o internal_a medium_fw-la 5._o the_o sensitive_a soul_n 1._o the_o object_n be_v the_o thing_n perceive_v by_o any_o of_o the_o sense_n as_o light_n by_o the_o eye_n sound_v or_o tremulous_a motion_n of_o the_o air_n by_o the_o ear_n odour_n by_o the_o nose_n taste_n by_o the_o tongue_n opium_n by_o the_o feel_n or_o as_o helmont_n call_v it_o the_o gustus_n or_o taste_n at_o stomach_n 2._o the_o external_n medium_fw-la of_o sensation_n be_v that_o which_o receive_v impression_n from_o the_o object_n and_o convey_v they_o to_o the_o organ_n of_o sensation_n thus_o the_o air_n convey_v sound_a or_o tremulous_a motion_n to_o the_o ear_n light_n to_o the_o eye_n and_o odour_n to_o the_o nose_n 3._o the_o organ_n be_v the_o part_n of_o the_o body_n that_o god_n have_v frame_v to_o receive_v those_o impression_n and_o communicate_v they_o to_o the_o animal_n spirit_n or_o internal_a medium_fw-la thus_o the_o eye_n be_v the_o organ_n to_o receive_v the_o impression_n of_o light_n the_o ear_n that_o of_o sound_n etc._n etc._n and_o the_o membrane_n in_o all_o part_n of_o the_o body_n be_v the_o organ_n that_o receive_v impression_n from_o object_n in_o the_o case_n of_o feel_v which_o be_v our_o main_n concern_v 4._o the_o internal_a medium_fw-la be_v the_o animal_n spirit_n that_o receive_v the_o impression_n from_o the_o organ_n and_o convey_v they_o to_o the_o sensitive_a soul_n 5._o the_o sensitive_a soul_n which_o perceive_v those_o impression_n convey_v to_o he_o by_o the_o animal_n spirit_n which_o perception_n be_v sensation_n i._o the_o part_n office_n or_o business_n of_o the_o object_n in_o the_o matter_n of_o sensation_n be_v to_o make_v a_o sufficient_a impression_n either_o upon_o the_o external_n medium_fw-la or_o air_n as_o in_o the_o case_n of_o hear_v etc._n etc._n or_o immediate_o upon_o the_o organ_n or_o membrane_n as_o in_o feel_v etc._n etc._n therefore_o if_o there_o be_v no_o impression_n of_o light_n sound_z or_o tremulous_a motion_n odour_n relish_v particle_n etc._n etc._n there_o can_v be_v no_o perception_n or_o if_o the_o inpression_n thereof_o be_v weak_a and_o faint_a the_o perception_n or_o sensation_n must_v be_v according_o or_o if_o it_o be_v so_o inconsiderable_a that_o it_o can_v at_o all_o affect_v the_o sensitive_a soul_n then_o be_v there_o no_o perception_n thereof_o for_o 1._o sensitive_a perception_n be_v not_o infinite_a because_o there_o be_v degree_n of_o light_n sound_z etc._n etc._n that_o can_v be_v perceive_v though_o they_o must_v be_v very_o small_a and_o inconsiderable_a thus_o the_o light_n of_o a_o candle_n at_o so_o great_a a_o distance_n that_o it_o can_v hardly_o be_v perceive_v be_v some_o degree_n of_o light_n and_o make_v its_o reflection_n proportionable_o from_o a_o wall_n tree_n etc._n etc._n yet_o can_v that_o reflect_v light_n from_o the_o wall_n or_o tree_n be_v perceive_v so_o the_o small_a thing_n can_v be_v perceive_v yet_o god_n have_v in_o his_o wisdom_n and_o goodness_n so_o order_v it_o that_o 2._o sensitive_a perception_n be_v of_o excessive_o small_a thing_n thus_o the_o sound_n of_o a_o pin_n head_n fall_v into_o a_o brass_n cauldron_n be_v hear_v at_o some_o distance_n the_o hundred_o part_n of_o a_o grain_n of_o very_a hot_a and_o bite_a thing_n be_v sensible_o taste_v the_o thousand_o part_n of_o a_o grain_n of_o ambergrise_n musk_n etc._n etc._n very_o sensible_o smell_v the_o light_n of_o a_o exceed_a small_a spark_n strike_v out_o between_o steel_n and_o flint_n be_v perceive_v at_o a_o great_a distance_n and_o light_n in_o general_n consist_v of_o such_o tenuious_n particle_n if_o material_a that_o none_o ever_o can_v take_v any_o estimate_n of_o their_o bulk_n so_o the_o feel_n at_o stomach_n take_v very_o eminent_a and_o remarkable_a notice_n of_o as_o be_v say_v the_o vomitery_a particle_n of_o crocus_n metallorum_fw-la or_o regulus_n of_o antimony_n which_o be_v so_o small_a that_o a_o thousand_o vomit_n thereof_o do_v not_o sensible_o diminish_v the_o crocus_n or_o regulus_n either_o in_o weight_n or_o bulk_n therefore_o it_o be_v no_o wonder_n if_o a_o grain_n of_o opium_n shall_v affect_v the_o feel_v so_o sensible_o as_o it_o do_v especial_o at_o stomach_n though_o it_o can_v make_v any_o considerable_a alteration_n of_o the_o blood_n 3._o that_o whatever_o affect_v or_o make_v impression_n upon_o the_o organ_n of_o sensation_n be_v in_o the_o same_o moment_n perceive_v by_o the_o sensitive_a soul_n so_o that_o it_o be_v no_o wonder_n that_o a_o grain_n of_o opium_n operate_v in_o so_o short_a a_o time_n that_o be_v as_o soon_o as_o a_o tincture_n thereof_o insinuate_v itself_o through_o the_o crusta_fw-la carnosa_fw-la to_o the_o sensile_a coat_n of_o the_o stomach_n whereas_o it_o must_v take_v a_o very_a long_a time_n if_o it_o operate_v as_o a_o alterative_a of_o the_o blood_n now_o note_v 1._o that_o there_o be_v no_o way_n for_o any_o thing_n to_o operate_v upon_o the_o sensitive_a soul_n in_o so_o small_a a_o quanty_n as_o opium_n operate_v or_o in_o so_o short_a a_o time_n as_o by_o affect_v the_o most_o exquisite_o dispose_v membrane_n at_o stomach_n 2._o that_o the_o speedy_a way_n that_o god_n have_v contrive_v for_o our_o refreshment_n comfort_n raise_v of_o our_o depress_a spirit_n upon_o any_o sudden_a occasion_n as_o in_o delinquium_n faint_n syncopes_fw-la leipothymy_n etc._n etc._n be_v by_o the_o sense_n especial_o that_o most_o exquisite_a sensation_n at_o stomach_n because_o refreshment_n by_o nourishment_n and_o alteration_n can_v be_v perform_v but_o in_o a_o long_a time_n wherein_o we_o may_v in_o many_o case_n perish_v before_o we_o can_v be_v relieve_v thereby_o thus_o a_o please_a and_o therefore_o comfortable_a odour_n excite_v the_o spirit_n in_o a_o moment_n the_o sight_n of_o a_o belove_a mistress_n or_o dear_a friend_n raise_v we_o immediate_o when_o we_o be_v most_o cast_v down_o as_o do_v also_o sweet_a melody_n and_o a_o aggreeable_a or_o pleasant_a sensation_n at_o stomach_n as_o of_o wine_n cordial_n hot_a spirit_n etc._n etc._n i_o hope_v none_o will_v say_v that_o music_n the_o sight_n of_o a_o bag_n of_o money_n etc._n etc._n send_v effâ—uvia's_n for_o that_o end_n yet_o be_v great_a comforter_n ii_o the_o part_n office_n or_o business_n of_o the_o external_n medium_fw-la in_o the_o
as_o appear_v by_o several_a place_n or_o passage_n of_o the_o premise_n and_o in_o the_o wake_a more_o than_o in_o such_o as_o be_v asleep_a 6._o it_o be_v manifest_a that_o they_o be_v elastic_a by_o their_o spring_v into_o a_o limb_n hold_v up_o or_o down_o and_o that_o with_o such_o force_n as_o to_o cause_v a_o great_a pain_n after_o they_o have_v be_v exclude_v from_o it_o by_o some_o accident_n as_o lean_v or_o press_v too_o hard_o upon_o a_o nerve_n etc._n etc._n for_o neither_o levity_n nor_o gravity_n can_v do_v so_o especial_o both_o up_o and_o down_o as_o be_v say_v nor_o be_v there_o any_o propulsory_a engine_n for_o they_o as_o be_v for_o the_o blond_n therefore_o it_o must_v be_v from_o their_o springiness_n 7._o they_o can_v not_o cause_v brisk_a and_o smart_a tremulous_a motion_n in_o the_o body_n if_o they_o be_v not_o elastic_a for_o such_o can_v be_v conceive_v by_o any_o mean_n without_o it_o but_o there_o be_v several_a brisk_a and_o smart_a tremulous_a motion_n cause_v by_o the_o animal_n spirit_n as_o in_o the_o shivering_n of_o ague_n fit_n fright_v cold_a surprise_v sudden_a or_o exquisite_a pain_n tremor_n of_o the_o hand_n head_z etc._n etc._n in_o old_a age_n in_o some_o conuâ—_n etc._n etc._n therefore_o the_o animal_n spirit_n that_o cause_v they_o be_v elastic_a 8._o muscle_n have_v no_o springiness_n of_o themselves_o when_o the_o animal_n spirit_n be_v exclude_v from_o they_o as_o in_o palsy_n etc._n etc._n but_o all_o muscle_n in_o their_o exertion_n be_v very_o springy_a insomuch_o that_o if_o you_o hold_v any_o of_o they_o back_o or_o restrain_v they_o from_o their_o motion_n and_o again_o sudden_o leave_v they_o at_o liberty_n during_o the_o exertion_n they_o or_o any_o part_n move_v by_o they_o will_v spring_v out_o very_o violent_o as_o in_o flip_v a_o arm_n hold_v back_o etc._n etc._n but_o nothing_o prove_v this_o matter_n better_o than_o the_o tongue_n in_o form_v the_o sound_n of_o the_o letter_n r_n for_o in_o that_o case_n the_o tongue_n after_o it_o be_v put_v in_o tension_n and_o exertion_n be_v sudden_o hit_v against_o the_o inside_n or_o gum_n of_o the_o upper_a tooth_n do_v thereupon_o as_o springy_a body_n use_v to_o do_v fall_v into_o a_o tremulous_a motion_n or_o jar_a that_o cause_v the_o snarl_a sound_n of_o r_n which_o nothing_o but_o springy_a matter_n can_v do_v 9_o be_v they_o not_o springy_a they_o can_v never_o convey_v the_o tremulous_a motion_n of_o sound_n to_o the_o sensitive_a soul_n and_o indeed_o over_o all_o the_o systeme_n of_o the_o nerve_n by_o which_o be_v cause_v as_o may_v be_v prove_v that_o motion_n of_o consent_n call_v dance_v and_o the_o finger_n etc._n etc._n to_o move_v and_o keep_v time_n with_o the_o music_n even_o when_o it_o or_o the_o finger_n be_v not_o as_o much_o as_o think_v of_o because_o the_o animal_n spirit_n have_v the_o same_o capacity_n with_o the_o air_n to_o receive_v and_o convey_v it_o by_o reason_n of_o their_o springiness_n and_o great_a by_o reason_n of_o their_o more_o forcible_a compression_n by_o the_o vigilative_a contraction_n supper_n add_v to_o the_o compression_n of_o the_o air_n under_o which_o they_o be_v as_o well_o as_o the_o air_n itself_o as_o plain_a reason_n tell_v we_o for_o that_o which_o compress_n the_o whole_a body_n must_v needs_o compress_v the_o animal_n spirit_n the_o experiment_n of_o the_o air-pump_n do_v confirm_v the_o same_o 10._o there_o can_v be_v no_o doubt_n but_o the_o animal_n spirit_n be_v nourish_v or_o sustain_v by_o the_o air_n if_o they_o be_v not_o air_n therefore_o they_o be_v elastic_a what_o need_v any_o more_o argument_n when_o several_a of_o the_o former_a be_v demonstrative_a and_o that_o 11._o all_o physician_n and_o philosopher_n that_o i_o know_v of_o do_v allow_v that_o the_o animal_n spirit_n be_v elastic_a second_o it_o be_v requisite_a as_o be_v say_v of_o the_o external_n medium_fw-la that_o they_o shall_v be_v compress_v to_o render_v they_o fit_a to_o convey_v impression_n and_o that_o they_o be_v compress_v be_v evident_a as_o be_v before_o intimate_v 1._o by_o the_o atmosphere_n 2._o by_o the_o vigilative_a contraction_n which_o make_v they_o much_o more_o dispose_v to_o convey_v impression_n than_o the_o external_n medium_fw-la beside_o that_o very_o often_o two_o other_o contradiction_n that_o be_v show_v in_o the_o remain_a part_n of_o this_o chapter_n be_v add_v thereto_o and_o that_o the_o animal_n spirit_n be_v whole_o contain_v in_o pipe_n to_o prevent_v their_o expansion_n and_o that_o of_o the_o narrow_a size_n that_o can_v well_o be_v imagine_v but_o the_o air_n or_o external_n medium_fw-la be_v at_o large_a in_o the_o atmosphere_n so_o that_o all_o the_o impression_n make_v upon_o the_o animal_n spirit_n be_v very_o tight_o close_o and_o smart_o convey_v nor_o have_v they_o but_o a_o little_a way_n to_o pass_v that_o be_v the_o length_n of_o the_o animal_n at_o most_o which_o also_o may_v be_v some_o advantage_n to_o small_a creature_n but_o in_o sleep_n the_o vigilative_a contraction_n be_v lose_v and_o the_o animal_n spirit_n thereupon_o expanded_a all_o impulse_n must_v needs_o be_v carry_v very_o faint_o both_o because_o the_o organ_n or_o membrane_n be_v indispose_v by_o relaxation_n and_o the_o animal_n spirit_n by_o expansion_n upon_o that_o relaxation_n for_o want_v of_o due_a compression_n to_o fit_v they_o thus_o have_v you_o after_o many_o vain_a inquiry_n the_o true_a mechanical_a cause_n of_o the_o difference_n of_o sensation_n sleep_v and_o wake_v and_o the_o plain_a reason_n why_o our_o motion_n be_v so_o feeble_a in_o sleep_n viz._n because_o the_o animal_n spirit_n have_v lose_v much_o of_o their_o force_n springiness_n etc._n etc._n for_o want_n of_o due_a compression_n by_o reason_n of_o the_o relaxation_n of_o all_o the_o vessel_n that_o include_v the_o spirit_n three_o it_o be_v in_o some_o measure_n requisite_a that_o the_o animal_n spirit_n shall_v have_v a_o homogeneous_a continuity_n as_o be_v show_v by_o the_o analogy_n of_o the_o external_n medium_fw-la which_o do_v not_o convey_v impression_n as_o well_o in_o the_o heat_n of_o the_o day_n as_o in_o the_o night_n or_o after_o sunset_n because_o its_o part_n be_v more_o discontinue_v and_o disgregated_a by_o the_o particle_n of_o heat_n fume_n etc._n etc._n in_o the_o day_n time_n nay_o if_o thing_n be_v discontinue_v they_o never_o carry_v impression_n so_o well_o though_o place_v contiguous_o afterward_o thus_o a_o long_a tree_n that_o convey_v sound_n so_o exact_o from_o one_o end_n to_o the_o other_o while_o all_o be_v continue_v and_o in_o one_o piece_n will_v not_o convey_v the_o sound_n so_o well_o if_o it_o be_v cut_v into_o many_o piece_n though_o they_o be_v afterward_o put_v close_o one_o to_o the_o other_o as_o to_o this_o matter_n of_o continuity_n in_o the_o animal_n spirit_n see_v it_o do_v not_o much_o concern_v we_o and_o that_o people_n in_o a_o state_n of_o health_n be_v suppose_v to_o have_v it_o and_o that_o it_o be_v not_o our_o business_n here_o to_o enter_v upon_o the_o consideration_n of_o nervous_a distemper_n i_o need_v not_o use_v any_o more_o word_n about_o it_o but_o that_o if_o it_o any_o way_n happen_v to_o be_v discontinue_v as_o either_o by_o the_o penury_n thereof_o that_o they_o do_v not_o quite_o fill_v all_o part_n of_o their_o vessel_n or_o any_o matter_n intercept_n their_o part_n or_o that_o the_o vessel_n shall_v be_v so_o relax_v or_o widen_v that_o the_o animal_n spirit_n can_v so_o well_o fill_v they_o up_o etc._n etc._n such_o cause_n must_v destroy_v or_o lessen_v sensation_n though_o the_o bare_a mix_n of_o fume_n with_o they_o will_v not_o consider_v the_o shortness_n of_o the_o way_n that_o impression_n be_v carry_v in_o animal_n much_o alter_v the_o case_n as_o you_o find_v fume_n in_o the_o air_n do_v not_o much_o hinder_a sound_n at_o the_o distance_n of_o a_o yard_n or_o two_o wherein_o it_o be_v insensible_a to_o common_a observer_n at_o least_o so_o that_o if_o some_o fume_n from_o a_o grain_n or_o two_o of_o opium_n do_v mingle_v with_o the_o animal_n spirit_n it_o will_v not_o cause_v a_o sensible_a difference_n of_o feel_v in_o the_o short_a space_n of_o the_o length_n of_o a_o animal_n but_o i_o have_v prove_v that_o no_o such_o fume_v from_o the_o opium_n mix_v with_o they_o therefore_o need_v say_v no_o more_o of_o this_o matter_n v._o the_o office_n or_o business_n of_o the_o sensitive_a soul_n in_o the_o oeconomy_n of_o sensation_n be_v to_o perceive_v the_o impression_n convey_v to_o he_o by_o the_o animal_n spirit_n that_o he_o may_v if_o he_o find_v they_o disagreeable_a bestir_v himself_o in_o defence_n of_o the_o animal_n first_o it_o be_v requisite_a he_o shall_v attend_v to_o all_o impression_n offer_v he_o by_o the_o animal_n spirit_n otherwise_o
which_o have_v be_v in_o some_o measure_n enumerate_v in_o the_o case_n of_o natural_a sleep_n in_o this_o chapter_n viz._n satisfaction_n composure_n of_o fret_n and_o commotion_n as_o of_o diary_n fever_n hysterick_a fit_n etc._n etc._n perspiration_n quiet_v of_o vomit_n hiccough_n etc._n etc._n lessen_v of_o feel_v and_o consequent_o a_o stop_n and_o moderation_n of_o all_o flux_n that_o depend_v upon_o irritation_n of_o humour_n as_o diarrhea_n dysentery_n catarrh_n vomit_n dryness_n of_o the_o mouth_n as_o in_o sleep_n for_o want_v of_o the_o contraction_n to_o squeeze_v the_o spital_n out_o of_o the_o glandule_n into_o the_o mouth_n nocturnal_a pollution_n etc._n etc._n but_o of_o the_o nature_n and_o effect_n of_o pleasure_n you_o will_v find_v more_o in_o the_o next_o chapter_n beside_o the_o vigilative_a and_o defensive_a contraction_n which_o seem_v to_o be_v thing_n of_o course_n upon_o wake_v and_o grievance_n the_o sensitive_a soul_n have_v a_o contraction_n at_o will_n as_o that_o of_o the_o pupilla_fw-la when_o a_o animal_n be_v intent_n upon_o see_v of_o the_o tympan_n when_o intent_n upon_o hear_v of_o the_o musole_n of_o the_o leg_n when_o intent_n upon_o walk_v and_o so_o of_o all_o the_o muscle_n of_o the_o body_n which_o i_o call_v intentive_a contraction_n that_o he_o can_v perform_v either_o along_o with_o or_o without_o the_o other_o contraction_n or_o without_o any_o great_a degree_n thereof_o as_o when_o one_o be_v considerable_o relax_v with_o the_o pleasure_n of_o wine_n very_o good_a news_n etc._n etc._n nay_o sometime_o even_o in_o sleep_n as_o be_v manifest_a by_o the_o noctamâ—uli_n or_o such_o as_o walk_v in_o their_o sleep_n and_o such_o as_o speak_v strike_v etc._n etc._n while_o asleep_a and_o as_o the_o defensive_a contraction_n do_v all_o it_o can_v in_o our_o defence_n without_o the_o direction_n of_o the_o will_n as_o in_o vomit_v sneeze_n purge_v etc._n etc._n upon_o sensible_a irritation_n so_o this_o intentive_a contraction_n do_v all_o it_o can_v to_o the_o same_o purpose_n by_o the_o direction_n and_o dictate_v thereof_o note_v that_o insensile_a grow_a thing_n that_o do_v not_o move_v as_o tree_n etc._n etc._n have_v none_o of_o these_o contraction_n but_o what_o happen_v by_o cold_a and_o compression_n of_o the_o atmosphere_n which_o be_v sufficient_a it_o seem_v for_o nutrition_n but_o not_o for_o sense_n and_o motion_n it_o follow_v that_o in_o complete_a syncopes_fw-la when_o the_o sensitive_a soul_n give_v over_o all_o contraction_n that_o we_o be_v much_o in_o the_o state_n of_o a_o plant._n all_o those_o three_o contraction_n viz._n the_o vigilative_a defensive_a and_o intentive_a do_v because_o they_o promote_v motion_n and_o cause_v it_o more_o or_o less_o as_o you_o find_v the_o vigilative_a cause_n much_o more_o of_o it_o than_o sleep_v and_o the_o defensive_a more_o than_o that_o etc._n etc._n spend_v the_o spirit_n cause_n weariness_n etc._n etc._n the_o vigilative_a contraction_n do_v of_o itself_o without_o any_o considerable_a grievance_n or_o labour_n that_o be_v without_o the_o denfensive_a or_o intentive_a contraction_n tire_v the_o sensitive_a soul_n in_o about_o 16_o hour_n hence_o it_o be_v that_o the_o idle_v person_n that_o be_v most_o free_a from_o care_n trouble_v or_o pain_n can_v well_o hold_v out_o without_o the_o recruit_v of_o sleep_n any_o long_o the_o defensive_a contraction_n or_o that_o of_o grievance_n be_v add_v to_o the_o vigilative_a contraction_n the_o spirit_n be_v fast_o spend_v and_o the_o person_n tire_v proportionable_o soon_o according_a as_o the_o grievance_n be_v more_o or_o less_o and_o consequent_o the_o endeavour_n of_o the_o sensitive_a soul_n to_o be_v rid_v thereof_o to_o both_o which_o contraction_n viz._n the_o vigilative_a and_o defensive_a if_o you_o add_v the_o intentive_a or_o labour_n then_o be_v you_o soon_o and_o more_o tire_v than_o by_o only_a those_o two_o former_a contraction_n for_o this_o last_o case_n be_v labour_v in_o pain_n or_o under_o a_o grievance_n which_o notorious_o tire_v man_n or_o beast_n soon_o than_o ordinary_a the_o direct_a contrary_n to_o which_o be_v sleep_v sound_o and_o sweet_o without_o trouble_n pain_n or_o dream_n for_o a_o dream_a condition_n have_v too_o much_o of_o the_o vigilative_a contraction_n in_o it_o to_o be_v pure_a relaxation_n and_o recruit_v now_o according_a as_o these_o contraction_n be_v or_o be_v not_o add_v one_o to_o another_o we_o be_v soon_o or_o late_a before_o we_o be_v tire_v speak_v general_o and_o not_o consider_v custom_n and_o habit_n which_o concern_v we_o not_o you_o see_v that_o all_o the_o three_o contraction_n conour_v do_v soon_o and_o sad_o tire_v we_o that_o no_o two_o of_o they_o tire_v we_o as_o much_o as_o the_o three_o together_o that_o iâ—_n neither_o the_o vigilative_a and_o defensive_a without_o the_o intentive_a nor_o the_o vigilative_a and_o intentive_a without_o the_o defensive_a and_o the_o vigilative_a alone_o lest_o of_o all_o yet_o allowance_n must_v be_v make_v for_o the_o intenseness_n of_o the_o defensive_a and_o intentive_a for_o either_o of_o these_o two_o be_v very_a intense_a may_v tire_v as_o much_o as_o both_o in_o a_o moderate_a degree_n thus_o a_o man_n may_v be_v tire_v with_o violent_a labour_n in_o four_o hour_n though_o not_o in_o pain_n as_o much_o as_o one_o that_o moderate_o labour_v in_o some_o small_a pain_n for_o the_o same_o time_n observe_v that_o we_o recruit_v in_o eight_o hour_n general_o speak_v as_o much_o by_o relaxation_n in_o sleep_n as_o we_o spend_v by_o vigilative_a contraction_n in_o sixteen_o i_o take_v the_o reason_n of_o that_o to_o be_v that_o relaxation_n widen_v all_o the_o passage_n of_o the_o body_n the_o nutriment_n be_v admit_v into_o they_o more_o full_o and_o free_o as_o the_o blood_n be_v into_o the_o skin_n in_o sleep_n and_o all_o relaxation_n which_o cause_n a_o efflorescence_n thereof_o in_o those_o case_n hence_o it_o be_v that_o we_o be_v so_o much_o recruit_v and_o nourish_v in_o sleep_n that_o child_n grow_v more_o than_o other_o proportionable_o that_o relaxer_n cause_v the_o breast_n etc._n etc._n to_o grow_v note_v what_o a_o mighty_a restaurative_a relaxation_n be_v by_o its_o help_n for_o eight_o hour_n in_o twenty_o four_o we_o can_v watch_v all_o and_o labour_v most_o of_o the_o other_o sixteen_o all_o the_o day_n of_o our_o life_n it_o follow_v that_o if_o we_o can_v any_o way_n half_o relax_v the_o vigilative_a contraction_n while_o we_o labour_v take_v a_o journey_n or_o the_o like_a that_o we_o may_v perform_v prodigious_o without_o be_v â—ired_v hence_o it_o be_v that_o because_o pleasure_n as_o have_v be_v intimate_v relax_n as_o grievance_n contract_v of_o which_o you_o may_v expect_v far_a proof_n in_o the_o next_o chapter_n that_o such_o as_o work_v or_o travel_n pleasant_o divert_v all_o the_o time_n be_v tire_v very_o little_a or_o nothing_o in_o a_o long_a time_n and_o that_o some_o will_v dance_v whole_a nightâ—_n with_o sweet_a music_n and_o agreeable_a belove_a company_n without_o be_v so_o much_o tire_v as_o they_o will_v be_v if_o they_o use_v the_o same_o motion_n for_o a_o quarter_n of_o the_o time_n without_o either_o of_o the_o pleasant_a diversion_n the_o like_a be_v to_o be_v say_v of_o any_o other_o pleasure_n as_o drink_v a_o good_a glass_n of_o generous_a wine_n every_o half_a hour_n or_o so_o often_o as_o to_o continue_v the_o sense_n of_o its_o pleasure_n at_o stomach_n all_o the_o time_n they_o labour_v or_o travel_v for_o it_o be_v a_o vulgar_a error_n though_o the_o universal_a sentiment_n of_o mankind_n both_o learned_a and_o unlearned_a that_o wine_n cordial_n etc._n etc._n do_v comfort_n elevate_v and_o excite_v the_o spirit_n as_o it_o be_v call_v by_o add_v their_o spirit_n to_o or_o join_v they_o with_o we_o whereas_o it_o be_v only_o by_o cause_v a_o pleasant_a sensation_n particular_o at_o stomach_n for_o which_o paradox_n i_o be_o oblige_v though_o in_o great_a haste_n to_o come_v to_o the_o explication_n of_o opium_n to_o give_v my_o reason_n which_o be_v as_o follow_v viz._n 1._o it_o can_v be_v imagine_v how_o a_o sensitive_a creature_n as_o such_o can_v conceive_v any_o comfort_n or_o be_v sensible_a thereof_o but_o by_o sensation_n to_o say_v he_o be_v comfort_v and_o not_o sensible_a of_o the_o comfort_n be_v a_o contradiction_n for_o comfort_n as_o such_o belong_v to_o a_o perceive_v be_v and_o a_o animal_n as_o such_o perceive_v nothing_o but_o by_o the_o sense_n and_o therefore_o there_o can_v be_v no_o comfort_n but_o by_o pleasant_a sensation_n nay_o as_o such_o it_o be_v his_o comfort_n so_o music_n pleasant_a sight_n odour_n and_o agreeable_a object_n of_o all_o the_o sense_n be_v comfortable_a because_o pleasant_a i_o hope_v that_o none_o will_v say_v that_o music_n sight_n good_a news_n &c._n &c._n which_o high_o comfort_n have_v any_o spirit_n to_o add_v to_o we_o the_o
be_v well_o remove_v this_o prove_v how_o useful_a removal_n may_v be_v and_o how_o convenient_a in_o plague_n time_n it_o will_v be_v to_o remove_v to_o the_o wind-side_n of_o a_o town_n or_o city_n that_o be_v taint_v according_a as_o the_o wind_n change_v and_o how_o convenient_a wind_n be_v to_o convey_v away_o the_o effluviams_n and_o good_a stomachick_a cordial_n that_o be_v warm_a and_o pleasant_a to_o fortify_v the_o stomach_n and_o open_v the_o pore_n which_o all_o thing_n that_o cause_v a_o sense_n of_o pleasure_n do_v as_o wine_n spirit_n etc._n etc._n to_o which_o if_o some_o good_a preparation_n of_o opium_n be_v add_v it_o will_v be_v most_o convenient_a how_o many_o story_n have_v we_o of_o person_n well_o fill_v with_o wine_n who_o wonderful_o escape_v infection_n i_o pray_v god_n this_o hint_n may_v be_v improve_v to_o the_o preservation_n of_o mankind_n therefore_o i_o add_v that_o much_o may_v be_v in_o a_o good_a quantity_n of_o wine_n in_o this_o case_n 1._o because_o quod_fw-la intus_fw-la est_fw-la prohibet_fw-la alienum_fw-la that_o be_v what_o be_v within_o hinder_v ingress_n of_o another_o thing_n 2._o because_o the_o perspiration_n will_v be_v the_o great_a both_o upon_o the_o account_n of_o the_o great_a open_n of_o the_o pore_n by_o the_o pleasure_n of_o the_o wine_n and_o the_o great_a quantity_n of_o matter_n to_o be_v perspire_v carry_v off_o the_o venomous_a particle_n 3._o because_o the_o sensitive_a soul_n be_v thereby_o much_o comfort_v refresh_v and_o invigorate_v but_o i_o will_v have_v the_o wine_n so_o use_v as_o to_o keep_v a_o continual_a warmth_n pleasure_n and_o comfort_n at_o stomach_n which_o be_v the_o main_a cause_n of_o all_o the_o good_a i_o think_v a_o glass_n every_o hour_n after_o take_v 2_o or_o 3_o at_o first_o may_v hit_v the_o mark_n best_o the_o reason_n of_o which_o will_v appear_v hereafter_o three_o the_o stomach_n be_v exquisite_a disposition_n to_o sensation_n above_o all_o other_o organ_n and_o membrane_n appear_v by_o this_o viz._n that_o the_o offence_n of_o the_o other_o organ_n of_o sensation_n even_o by_o their_o proper_a object_n do_v often_o affect_v the_o stomach_n more_o than_o those_o very_a sense_n or_o organ_n themselves_o for_o instance_n if_o we_o smell_v a_o great_a stench_n the_o stomach_n be_v often_o more_o offend_v thereat_o than_o the_o nose_n as_o be_v manifest_a from_o the_o vomit_n faint_n and_o deliquium_n that_o be_v cause_v by_o the_o stomach_n upon_o that_o account_n so_o the_o bare_a see_v feel_v and_o taste_v of_o a_o nasty_a thing_n do_v cause_n nauseas_fw-la etc._n etc._n at_o stomach_n yea_o the_o very_a name_n of_o such_o thing_n have_v much_o offend_v it_o and_o cause_v such_o effect_n which_o may_v be_v think_v very_o strange_a consider_v that_o there_o pass_v no_o effluvias_fw-la from_o the_o sound_n of_o word_n but_o the_o reason_n will_v appear_v in_o the_o follow_a paragraph_n four_o all_o passion_n commotion_n and_o perturbation_n that_o happen_v in_o the_o body_n do_v often_o affect_v the_o stomach_n and_o sometime_o so_o grievous_o as_o to_o cause_n nauseas_fw-la vomit_n great_a anxiety_n at_o stomach_n faint_n etc._n etc._n thus_o fear_v terror_n surprise_v anger_n grief_n pain_n in_o other_o part_n etc._n etc._n cause_v some_o motion_n in_o the_o animal_n more_o than_o ordinary_a of_o which_o the_o stomach_n be_v sensible_a do_v cause_n the_o aforesaid_a disturbance_n therefore_o it_o be_v no_o wonder_n if_o the_o hear_v one_o mention_n a_o nasty_a thing_n which_o cause_v a_o abhorrence_n and_o the_o motion_n consequent_a thereunto_o shall_v as_o be_v say_v in_o the_o precedent_n paragraph_n cause_v the_o nice_a stomach_n to_o be_v offend_v it_o be_v most_o manifest_a from_o the_o premise_n that_o no_o organ_n or_o membrane_n can_v compare_v with_o the_o stomach_n as_o to_o its_o exquisite_a disposition_n for_o sensation_n it_o follow_v then_o that_o grievance_n or_o pleasure_n at_o stomach_n must_v have_v the_o great_a effect_n 1._o because_o the_o intenseness_n of_o either_o will_v be_v proportionable_a to_o the_o sensation_n 2._o because_o the_o power_n of_o the_o animal_n that_o be_v to_o defend_v it_o which_o be_v contraction_n be_v affect_v according_a to_o the_o sensation_n and_o that_o it_o be_v there_o most_o requisite_a sensible_o to_o affect_v they_o 3._o because_o what_o affect_v the_o stomach_n influence_n the_o whole_a animal_n more_o than_o the_o sensation_n of_o any_o other_o part._n 4._o because_o of_o the_o considerable_a stay_v that_o thing_n make_v at_o stomach_n to_o cause_n grievance_n or_o pleasure_n whereas_o that_o of_o pleasure_n be_v general_o very_o momentary_a in_o other_o case_n 5._o because_o be_v within_o the_o body_n we_o carry_v our_o pleasure_n or_o grievance_n with_o we_o as_o a_o vade_fw-la mecum_fw-la wherever_o we_o go_v and_o therefore_o 6._o it_o be_v a_o pleasure_n etc._n etc._n that_o can_v so_o well_o be_v take_v away_o from_o we_o as_o that_o of_o the_o tongue_n ear_n nose_n eye_n etc._n etc._n may_v by_o remove_v the_o object_n and_o therefore_o it_o remain_v with_o we_o in_o our_o very_a sleep_n as_o far_o as_o we_o be_v capable_a of_o sensation_n at_o that_o time_n cause_v pleasant_a dream_n etc._n etc._n and_o so_o agreeable_o entertain_v we_o sleep_v or_o wake_v when_o the_o pleasure_n of_o all_o the_o other_o sense_n fail_v we_o which_o will_v appear_v far_o hereafter_o the_o pleasure_n at_o stomach_n excel_v even_o that_o of_o venery_n if_o not_o in_o intenseness_n yet_o in_o several_a other_o respect_n viz._n 1._o because_o of_o its_o duration_n that_o of_o venus_n be_v momentary_a but_o that_o of_o wine_n at_o stomach_n last_v a_o good_a while_n and_o that_o of_o opium_n many_o hour_n it_o be_v therefore_o that_o the_o effect_n of_o these_o two_o be_v more_o remarkable_a and_o take_v notice_n of_o 2._o because_o that_o at_o stomach_n may_v be_v continue_v as_o long_o as_o we_o please_v by_o a_o new_a supply_n of_o wine_n opium_n cordial_n etc._n etc._n 3._o because_o it_o may_v be_v excite_v when_o and_o as_o often_o as_o we_o please_v if_o we_o have_v those_o cordial_n at_o hand_n 4._o because_o it_o be_v not_o attend_v with_o any_o expense_n of_o strength_n depression_n of_o spirit_n etc._n etc._n as_o that_o of_o venery_n but_o the_o quite_o contrary_a viz._n with_o more_o vigour_n elevation_n of_o the_o spirit_n etc._n etc._n one_o be_v by_o emission_n and_o the_o other_o upon_o admission_n of_o what_o be_v agreeable_a it_o be_v for_o the_o several_a reason_n contain_v in_o the_o premise_n that_o the_o effect_n of_o grievance_n as_o hunger_n etc._n etc._n or_o pleasure_n be_v more_o considerable_a and_o remarkable_a at_o stomach_n and_o that_o thing_n agreeable_a thereto_o have_v by_o way_n of_o eminence_n gain_v the_o name_n of_o cordial_n that_o wine_n spirit_n opium_n etc._n etc._n do_v cause_n a_o more_o permanent_a and_o notable_a gaity_n pleasantness_n good_a humour_n serenity_n promptitude_n ovation_n of_o the_o spirit_n or_o sensitive_a soul_n bravery_n courage_n magnanimity_n euphory_n or_o easy_a undergo_n of_o business_n relaxation_n with_o all_o its_o effect_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la perspiration_n etc._n etc._n which_o be_v hardly_o note_v in_o other_o short_a pleasure_n unless_o it_o be_v in_o that_o eminent_a though_o short_a one_o of_o venus_n which_o be_v a_o pleasure_n of_o the_o same_o sense_n of_o feel_v as_o that_o of_o opium_n and_o wine_n be_v therefore_o please_v the_o stomach_n be_v one_o of_o the_o great_a thing_n to_o be_v regard_v in_o the_o practice_n of_o physic_n to_o comfort_n satisfy_v or_o compose_v the_o spirit_n by_o which_o mean_n i_o have_v often_o perform_v such_o cure_n that_o neither_o i_o nor_o i_o suppose_v any_o other_o can_v otherwise_o perform_v namely_o dejection_n of_o appetite_n untowardness_n at_o stomach_n etc._n etc._n when_o all_o the_o ordinary_a and_o usual_a mean_n have_v fail_v by_o ask_v they_o what_o they_o most_o desire_a or_o long_v for_o and_o let_v they_o have_v it_o or_o if_o they_o can_v not_o tell_v of_o any_o thing_n that_o they_o long_v for_o i_o have_v mention_v to_o they_o all_o the_o relish_v thing_n that_o i_o can_v think_v of_o and_o such_o as_o be_v grateful_a to_o the_o stomach_n till_o they_o fasten_v upon_o somewhat_o that_o they_o like_v or_o fancy_v and_o then_o be_v give_v they_o it_o general_o have_v the_o desire_a success_n the_o stomach_n be_v grieve_v for_o it_o will_v concern_v we_o to_o know_v how_o because_o opium_n cause_v vomit_v etc._n etc._n general_o speak_v 1._o by_o thing_n hard_a of_o digestion_n as_o heavy_a bread_n mushroom_n rosin_n and_o such_o like_a 2._o by_o thing_n acrimonious_a or_o pungent_a as_o vomitory_n of_o asarabacca_n groundsil_n squill_n etc._n etc._n which_o abound_v with_o volatile_a salt_n 3._o by_o thing_n that_o stick_v to_o the_o stomach_n which_o
grievance_n cause_v contraction_n as_o have_v be_v manifest_o show_v 2._o because_o it_o cause_v a_o liberal_a perspiration_n which_o be_v a_o certain_a effect_n of_o relaxation_n as_o the_o want_n of_o it_o be_v of_o constriction_n and_o that_o it_o cause_v perspiration_n be_v most_o certain_a by_o statick_a experiment_n and_o demonstration_n sanctorius_n sect._n 7._o aph._n 19_o etc._n etc._n 3._o because_o the_o pleasure_n of_o wine_n and_o the_o venereal_a act_n manifest_o loosen_v all_o the_o limb_n as_o sleep_n do_v 4._o because_o that_o in_o those_o pleasure_n as_o also_o upon_o the_o sight_n of_o a_o belove_a mistress_n etc._n etc._n the_o eye_n look_v deadish_a by_o reason_n of_o the_o laxity_n of_o the_o cornea_n and_o that_o the_o pupilla_fw-la be_v dilate_v 5._o the_o skin_n as_o have_v be_v intimate_v look_v florid_n which_o make_v the_o ancient_n say_v that_o the_o blood_n and_o spirit_n come_v outward_a to_o meet_v the_o good_a and_o agreeable_a thing_n 6._o because_o all_o pleasure_n that_o be_v consistent_a with_o lie_v or_o sit_v still_o in_o a_o silent_a quiet_a manner_n incline_v we_o to_o sleep_v as_o music_n pleasant_a frication_n of_o the_o head_n back_o or_o any_o itch_a part_n sweet_a and_o acceptable_a o_o lour_v a_o thing_n of_o very_a acceptable_a taste_n hold_v in_o the_o mouth_n wine_n meat_n venus_n the_o pleasant_a sound_n of_o the_o fall_n of_o water_n whistle_v wind_n rock_v undulate_v in_o hammock_n etc._n etc._n 7._o because_o in_o coition_n it_o relax_n the_o neck_n of_o the_o womb_n to_o admit_v the_o animal_n elixir_n vitæ_fw-la of_o which_o we_o have_v most_o evident_a proof_n and_o some_o eminent_a instance_n that_o i_o forbear_v the_o relation_n of_o out_o of_o modesty_n 8._o pleasure_n cause_v a_o large_a and_o wide_a pulse_n as_o relaxation_n always_o do_v 9_o a_o loss_n or_o great_a diminution_n of_o sensation_n as_o in_o the_o venereal_a act._n which_o if_o it_o be_v of_o continuance_n will_v exact_o imitate_v opium_n in_o its_o effect_n upon_o drink_v wine_n etc._n etc._n the_o effect_n of_o which_o be_v of_o great_a duration_n and_o by_o take_v somewhat_o into_o the_o stomach_n as_o opium_n be_v be_v very_o like_o that_o of_o opium_n 10._o intense_a pleasure_n joy_n etc._n etc._n do_v frequent_o cause_v ecstasy_n syncopes_fw-la leipothymy_n which_o be_v only_o great_a relaxation_n as_o have_v be_v show_v 11._o you_o see_v that_o the_o pleasure_n of_o wine_n cause_v falter_v of_o the_o tongue_n which_o be_v the_o effect_n of_o relaxation_n as_o in_o sleep_n palsy_n etc._n etc._n and_o relax_n the_o whole_a body_n 12._o wine_n also_o prevent_v lassitude_n as_o all_o pleasant_a diversion_n do_v and_o cause_v all_o the_o effect_n of_o relaxation_n as_o take_v away_o pain_n cause_v a_o deadness_n of_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la floridity_n of_o the_o skin_n perspiration_n diminution_n of_o sensation_n mirth_n good_a humour_n sleep_v etc._n etc._n nâ—te_n that_o pleasure_n be_v general_o from_o external_n object_n and_o also_o short_a slight_a and_o transitory_a be_v the_o true_a reason_n of_o the_o great_a penury_n of_o thing_n that_o bear_v any_o complete_a analogy_n to_o opium_n in_o its_o great_a effect_n which_o make_v it_o seem_v more_o amaze_a and_o confound_v people_n whereas_o all_o the_o difference_n be_v nothing_o but_o its_o cause_v a_o internal_a intense_a and_o permanent_a pleasure_n all_o pleasure_n have_v the_o same_o effect_n but_o that_o they_o be_v short_a slight_a fade_a external_a inconsiderable_a intermit_a interrupt_v by_o some_o grievous_a object_n thought_n passion_n as_o fear_v care_n solicitude_n melancholy_a etc._n etc._n but_o the_o pleasure_n of_o opium_n we_o carry_v within_o we_o continual_o whether_o we_o will_v or_o no_o wake_v and_o sleep_v without_o any_o intermission_n or_o interruption_n and_o that_o in_o a_o high_a degree_n for_o many_o hour_n doubtless_o that_o of_o venus_n if_o iâ—_n be_v half_a as_o last_a will_v be_v as_o dangerous_a as_o that_o of_o a_o great_a do_v of_o opium_n or_o wine_n drink_v in_o a_o vast_a quantity_n which_o be_v in_o a_o manner_n as_o dangerous_a as_o opium_n and_o for_o the_o same_o reason_n viz._n by_o over-dosing_a a_o great_a relaxer_n by_o the_o pleasure_n it_o cause_n the_o cause_n why_o the_o pleasure_n of_o the_o venereal_a act_n as_o a_o large_a do_v of_o wine_n opium_n etc._n etc._n take_v away_o pain_n be_v 1._o because_o the_o sensitive_a soul_n can_v attend_v to_o two_o thing_n at_o once_o therefore_o when_o a_o sense_n of_o pleasure_n be_v introduce_v there_o can_v be_v at_o the_o same_o time_n a_o sense_n of_o pain_n which_o though_o not_o note_v in_o short_a transient_a and_o desultory_a pleasure_n as_o almost_o all_o be_v beside_o that_o of_o wine_n and_o opium_n yet_o the_o more_o permanent_a do_v exact_v our_o notice_n and_o attention_n because_o they_o exclude_v pain_n for_o so_o considerable_a a_o time_n that_o they_o amaze_v we_o 2._o because_o the_o sensitive_a soul_n attend_v more_o willing_o to_o pleasure_n than_o to_o pain_n so_o that_o pleasure_n engross_v his_o attention_n as_o be_v intimate_v 3._o because_o pleasure_n and_o pain_n or_o displeasure_n be_v contrary_n and_o can_v co-exist_a in_o the_o same_o subject_a or_o sensitive_a soul_n therefore_o when_o pleasure_n affect_v it_o pain_n can_v 4._o because_o relaxation_n which_o be_v the_o mechanical_a and_o main_a reason_n give_v such_o liberty_n to_o the_o animal_n spirit_n to_o expand_v that_o they_o become_v unfit_a for_o want_v of_o compressure_n to_o convey_v any_o impression_n smart_o which_o be_v requisite_a to_o cause_v a_o sense_n of_o pain_n that_o be_v cause_v by_o a_o smart_a impression_n to_o which_o you_o may_v add_v that_o 5._o pleasure_n and_o relaxation_n where_o they_o continue_v as_o in_o the_o case_n of_o wine_n and_o opium_n do_v high_o improve_v one_o another_o because_o they_o mutual_o cause_v one_o another_o for_o pleasure_n cause_v relaxation_n and_o relaxation_n as_o you_o sin_v in_o a_o sweet_a slumber_n etc._n etc._n pleasure_n so_o that_o permanent_a pleasure_n must_v high_o advance_v relaxation_n which_o take_v away_o pain_n by_o prevent_v all_o smartness_n of_o impression_n by_o the_o now_o yield_a nature_n of_o the_o expanded_a animal_n spirit_n which_o be_v as_o air_n in_o a_o gut_n half_n full_a or_o a_o rowl_n of_o card_a cotten_n or_o wool_n fit_a only_a to_o carry_v a_o gentle_a or_o no_o impression_n to_o the_o far_a end_n thereof_o so_o that_o upon_o the_o give_n of_o opium_n when_o the_o pâ—in_n do_v once_o begin_v to_o diminish_v it_o be_v not_o long_o afterward_o before_o it_o go_v quite_o off_o for_o if_o the_o pleasure_n do_v but_o take_v off_o one_o in_o ten_o of_o the_o pain_n it_o be_v a_o sign_n that_o it_o will_v be_v a_o easy_a matter_n for_o it_o that_o be_v upon_o the_o improvement_n for_o the_o reason_n aforesaid_a to_o overcome_v one_o in_o nine_o and_o yet_o much_o easy_a to_o overcome_v one_o in_o eight_o and_o so_o on_o therefore_o it_o be_v a_o certain_a sign_n that_o you_o have_v give_v enough_o to_o take_v away_o the_o pain_n if_o it_o once_o sensible_o decrease_v and_o consequent_o all_o physician_n shall_v then_o not_o give_v any_o more_o opium_n though_o the_o pain_n be_v not_o yet_o quite_o off_o for_o if_o the_o relaxation_n cause_v by_o pleasant_a sensation_n be_v of_o force_n enough_o to_o overcome_v the_o great_a contraction_n by_o the_o great_a pain_n which_o oppose_v it_o more_o strong_o it_o will_v suffice_v to_o overcome_v the_o less_o this_o intimate_v and_o it_o be_v experience_v that_o dose_n must_v be_v proportion_v to_o the_o pain_n for_o though_o a_o few_o glass_n of_o wine_n may_v take_v off_o the_o sense_n of_o a_o small_a pain_n more_o must_v be_v drink_v to_o take_v off_o a_o great_a and_o so_o of_o opium_n because_o the_o contraction_n by_o pain_n resist_v the_o relaxation_n by_o pleasure_n have_v show_v how_o sleep_n and_o pleasure_n take_v away_o pain_n by_o relaxation_n permit_v the_o animal_n spirit_n to_o expand_v and_o grow_v unfit_a to_o carry_v impression_n smart_o and_o that_o therefore_o sleep_v stop_n or_o moderate_v all_o flux_n that_o depend_v upon_o irritation_n of_o the_o sensile_a part_n to_o cause_v they_o to_o contract_n and_o squeeze_v out_o the_o humour_n that_o cause_v the_o flux_n while_o the_o same_o relaxation_n open_v the_o pore_n and_o so_o let_v out_o the_o fume_n of_o the_o body_n which_o only_o like_o smoke_n in_o a_o chimney_n require_v a_o open_a passage_n by_o reason_n of_o their_o levity_n which_o carry_v they_o off_o it_o plain_o appear_v how_o pleasure_n that_o take_v away_o the_o sense_n of_o pain_n or_o irritation_n by_o the_o like_a relaxation_n must_v stop_v the_o first_o sort_n of_o flux_n that_o require_v the_o irritation_n to_o contract_v the_o part_n and_o promote_v that_o of_o perspiration_n as_o in_o sleep_n which_o require_v
only_o the_o open_n of_o the_o pore_n so_o that_o i_o need_v add_v no_o more_o word_n about_o it_o for_o the_o fame_n cause_o must_v have_v the_o same_o effect_n therefore_o a_o intense_a and_o permanent_a pleasure_n must_v have_v all_o or_o much_o of_o the_o effect_n of_o sleep_n in_o general_n as_o have_v be_v show_v it_o can_v therefore_o be_v any_o wonder_n that_o opium_n cause_v sleep_n yet_o be_v there_o difference_n between_o sleep_n and_o pleasure_n upon_o other_o account_n though_o not_o upon_o the_o account_n of_o relaxation_n viz._n because_o 1._o that_o sleep_n require_v also_o a_o rest_n of_o spirit_n or_o the_o sensitive_a soul_n whereas_o relaxation_n by_o pleasure_n be_v consistent_a with_o motion_n of_o the_o spirit_n either_o by_o outward_a action_n or_o internal_a motion_n thereof_o by_o some_o inward_a cause_n hence_o it_o be_v first_o that_o we_o can_v labour_v travel_v dance_n etc._n etc._n and_o enjoy_v pleasure_n and_o its_o relaxation_n volantary_a motion_n which_o require_v only_o a_o particular_a contraction_n of_o some_o part_n by_o the_o dictate_v of_o the_o will_n or_o appetite_n be_v consistent_a with_o the_o general_a relaxation_n by_o reason_n of_o the_o prerogative_n of_o the_o will._n thus_o do_v we_o move_v though_o more_o relax_v or_o when_o most_o merry_a and_o please_v with_o wine_n nay_o some_o will_v walk_v in_o their_o sleep_n when_o extreme_o intâ—t_v upon_o a_o thing_n as_o when_o awake_a which_o show_v the_o roll_a power_n of_o intentive_a contraction_n that_o may_v be_v exercise_v with_o relaxation_n and_o other_o contraction_n as_o the_o will_n itself_o may_v or_o intentive_a appetite_n second_o that_o pain_n be_v often_o take_v away_o by_o opium_n by_o the_o diversion_n and_o relaxation_n cause_v by_o pleasure_n and_o its_o inconsistence_n with_o pain_n without_o sleep_n which_o require_v the_o aforesaid_a rest_n that_o bare_a relaxation_n as_o such_o do_v not_o include_v though_o relaxation_n suffice_v to_o take_v away_o pain_n three_o that_o opium_n do_v by_o its_o heat_n active_a particle_n etc._n etc._n hinder_v some_o person_n to_o sleep_n yet_o have_v you_o in_o both_o these_o last_o case_n all_o other_o effect_n of_o opium_n as_o pleasure_n indolence_n relaxation_n etc._n etc._n which_o show_v how_o far_o sleep_v be_v from_o be_v a_o constant_a and_o the_o most_o genuine_a effect_n of_o opium_n as_o be_v general_o imagine_v however_o we_o must_v allow_v it_o as_o have_v be_v show_v to_o be_v a_o mighty_a disposer_n of_o we_o towards_o sleep_n because_o of_o the_o relaxation_n that_o it_o cause_n which_o be_v the_o main_a requisite_a of_o sleep_n ii_o that_o pleasure_n do_v without_o nutritive_a refection_n by_o the_o complacency_n it_o cause_v in_o the_o sensitive_a soul_n produce_v comfort_n satisfaction_n composure_n elevation_n of_o the_o spirit_n euphory_n etc._n etc._n of_o which_o sleep_n be_v either_o not_o at_o all_o capable_a or_o but_o in_o a_o low_a degree_n proportionable_a to_o the_o sensation_n that_o it_o have_v which_o be_v but_o little_a however_o a_o pleasure_n that_o remain_v within_o we_o even_o in_o our_o sleep_n as_o that_o of_o opium_n may_v well_o cause_v pleasant_a dream_n etc._n etc._n the_o reader_n may_v observe_v that_o in_o all_o place_n where_o i_o mention_v that_o relaxation_n cause_v the_o open_n of_o the_o pore_n that_o i_o speak_v only_o of_o perspiration_n as_o the_o effect_n thereof_o without_o mention_v sweat_n 1._o because_o perspiration_n be_v the_o only_a constant_a and_o infallible_a effect_n thereof_o by_o reason_n that_o the_o levity_n of_o the_o fume_n cause_v they_o as_o certain_o to_o pass_v at_o the_o pore_n when_o open_a as_o smoke_n pass_v up_o at_o a_o open_a chimney_n 2._o because_o sweat_n be_v a_o uncertain_a effect_n thereof_o for_o it_o require_v that_o the_o body_n be_v well_o fill_v with_o moisture_n though_o there_o be_v a_o relaxation_n or_o open_v of_o the_o pore_n as_o hypocrates_n very_o right_o intimate_v in_o that_o aphorism_n of_o his_o that_o i_o cite_v in_o the_o last_o chapter_n 1._o because_o sweat_n have_v not_o that_o levity_n that_o the_o fume_n have_v to_o cause_v it_o ready_o to_o move_v as_o soon_o as_o the_o pore_n be_v open_a 2._o because_o relaxation_n be_v more_o apt_a to_o receive_v detain_v and_o suspend_v humour_n 3._o because_o the_o protrusive_a motion_n of_o the_o heart_n be_v weak_a in_o all_o relaxation_n and_o all_o see_v how_o much_o its_o vigorous_a protrusion_n contribute_v to_o sweat_v upon_o action_n 4._o because_o a_o heartful_a of_o blood_n do_v not_o make_v such_o a_o push_v forward_o when_o the_o artery_n be_v widen_v by_o relaxation_n 5._o sweat_n have_v more_o of_o continuity_n consistence_n and_o viscidity_n can_v flow_v out_o so_o ready_o at_o the_o pore_n as_o a_o mere_a vapour_n however_o if_o the_o body_n be_v full_a of_o moisture_n and_o the_o pore_n open_a there_o be_v a_o natural_a course_n that_o way_n and_o the_o heart_n continual_o protrude_a it_o far_o and_o far_o a_o sweat_n follow_v and_o that_o whether_o they_o sleep_v or_o not_o 3._o because_o sweat_v as_o be_v in_o some_o sort_n intimate_v be_v sometime_o cause_v by_o the_o strong_a protrusion_n of_o the_o heart_n as_o in_o motion_n etc._n etc._n and_o upon_o that_o account_n come_v more_o under_o the_o title_n of_o flux_n cause_v by_o contraction_n than_o relaxation_n of_o which_o perspiration_n be_v a_o constant_a effect_n 4._o because_o sweat_n be_v sometime_o cause_v by_o another_o sort_n of_o contraction_n viz._n the_o compression_n of_o the_o whole_a body_n by_o a_o violent_a defensive_a contraction_n as_o in_o great_a terror_n agony_n and_o the_o like_a cause_v thereby_o as_o be_v show_v by_o the_o comparison_n of_o a_o wet_a sheet_n wring_v who_o out_o side_n be_v cold_a a_o cold_a sweat_n which_o that_o of_o alum_n or_o vitriol_n cause_v a_o exudation_n of_o the_o spital_n into_o the_o mouth_n by_o constr_v the_o part_n do_v illustrate_v very_o plain_o therefore_o you_o see_v i_o have_v just_a cause_n not_o to_o mention_v sweat_n as_o a_o certain_a and_o proper_a effect_n of_o relaxation_n without_o good_a distinction_n first_o make_v though_o unwary_a author_n that_o talk_v any_o thing_n one_o after_o another_o not_o know_v what_o they_o say_v make_v it_o their_o common_a say_n that_o sleep_n and_o opium_n stop_v all_o flux_n but_o sweat_n whereas_o they_o shall_v have_v rather_o say_v but_o perspiration_n for_o opium_n and_o sleep_n also_o will_v sometime_o hinder_v sweat_n viz._n that_o from_o pain_n terror_n etc._n etc._n and_o that_o as_o happen_v just_a upon_o awake_v by_o the_o strong_a systole_n of_o the_o heart_n and_o contraction_n of_o the_o whole_a body_n and_o that_o also_o upon_o motion_n unless_o the_o body_n be_v as_o be_v say_v full_a of_o humour_n or_o moisture_n therefore_o it_o be_v a_o vulgar_a error_n to_o say_v sweat_n instead_o of_o perspiration_n in_o the_o case_n aforesaid_a you_o may_v remember_v that_o in_o the_o beginning_n of_o this_o chapter_n i_o conclude_v that_o a_o sal-volatile-oleosum_a such_o as_o semen_n humanum_fw-la wherein_o the_o oily_a and_o volatile_a part_n be_v strict_o combine_v and_o the_o volatile_a somewhat_o more_o active_a or_o acrimonious_a than_o that_o in_o our_o membrane_n in_o general_a must_v be_v most_o please_v to_o the_o membrane_n by_o a_o fine_a titillation_n etc._n etc._n therefore_o if_o opium_n shall_v prove_v to_o be_v such_o we_o need_v not_o wonder_v at_o its_o titillate_v to_o venery_n nor_o indeed_o its_o cause_v a_o high_a sense_n of_o pleasure_n upon_o any_o membrane_n they_o be_v all_o of_o the_o same_o nature_n but_o especial_o upon_o the_o most_o exquisite_o dispose_v membrane_n of_o the_o stomach_n and_o the_o venereal_a part_n nor_o consequent_o its_o cause_v all_o the_o aforementioned_a effect_n of_o intense_a pleasure_n as_o comfort_n satisfaction_n ovation_n etc._n etc._n of_o the_o sensitive_a soul_n or_o spirit_n and_o relaxation_n of_o all_o the_o sensile_a part_n which_o will_v easy_o solve_v all_o the_o phenomenas_n of_o opium_n however_o numerous_a mysterious_a and_o seem_o contradictory_n as_o you_o will_v find_v let_v we_o therefore_o now_o see_v whether_o opium_n be_v such_o a_o sal-volatile-oleosum_a wherein_o the_o volatile_a particle_n be_v somewhat_o more_o active_a or_o acrimonious_a than_o we_o and_o the_o oily_a and_o volatile_a part_n strict_o combine_v if_o so_o the_o business_n be_v do_v the_o nail_n be_v hit_v on_o the_o head_n and_o i_o may_v say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d chap._n xv._o show_v what_o be_v the_o principle_n of_o opium_n and_o which_o cause_n the_o good_a and_o bad_a effect_n thereof_o have_v try_v if_o not_o tire_v your_o patience_n and_o premise_v what_o i_o think_v necessary_a in_o the_o forego_n chapter_n i_o now_o reassume_v the_o thread_n of_o my_o discourse_n as_o for_o the_o passive_a principle_n of_o opium_n which_o do_v or_o signify_v little_a or_o nothing_o
by_o titillation_n upon_o the_o account_n of_o the_o volatile_a salt_n which_o appear_v by_o its_o exciting_a to_o venery_n at_o the_o same_o time_n as_o all_o those_o volatiles_fw-la do_v 16._o it_o be_v cause_v vomit_n as_o it_o often_o do_v be_v a_o undoubted_a sign_n of_o its_o volatile_a salt_n for_o all_o vegetable_a vomit_n be_v such_o upon_o that_o account_n unless_o it_o be_v such_o as_o may_v move_v vomit_v mere_o by_o their_o be_v loathe_v or_o nauseated_a which_o only_o cause_v some_o particular_a person_n to_o vomit_v but_o such_o as_o be_v constant_a vomitory_n be_v so_o upon_o the_o account_n of_o their_o volatile_a salt_n as_o asaerabocea_n groundsil_n foxâ—loves_n squill_n etc._n etc._n give_v in_o a_o sufficient_a quantity_n 17._o it_o be_v lively_a effect_n as_o courage_n etc._n etc._n prove_v the_o same_o 18._o all_o author_n that_o have_v be_v curious_a do_v agree_v that_o opium_n abound_v with_o volatile_a salt_n as_o helmont_n lemery_n le_fw-fr febure_n wedelius_n and_o indeed_o every_o one_o that_o ever_o i_o read_v though_o most_o of_o they_o attribute_v its_o effect_n to_o a_o sulphur_n which_o make_v their_o testimony_n of_o its_o volatile_a salt_n the_o strong_a as_o be_v force_v to_o confess_v it_o against_o their_o hypothesise_n 19_o after_o its_o fermentation_n with_o leaven_n in_o a_o sand_n heat_v for_o 14_o day_n it_o afford_v a_o volatile_a salt_n in_o good_a quantity_n but_o mix_v with_o oil_n which_o be_v separate_v from_o it_o by_o dissolution_n in_o water_n filtring_n etc._n etc._n 20._o it_o be_v spirit_n ferment_n with_o acid_n therefore_o be_v volatile_a last_o to_o pin_n up_o all_o if_o you_o either_o chemical_o analyse_v it_o by_o fire_n or_o set_v it_o to_o crystalize_v after_o it_o be_v evaporate_v to_o a_o due_a condition_n so_o to_o do_v it_o afford_v a_o great_a quantity_n of_o volatile_a salt_n therefore_o it_o be_v pass_v all_o manner_n of_o doubt_n for_o which_o end_n i_o have_v the_o long_o and_o more_o particular_o insist_v upon_o this_o point_n that_o it_o be_v high_o impregnate_v with_o volatile_a salt_n but_o as_o i_o say_v in_o the_o last_o chapter_n it_o be_v not_o enough_o for_o it_o to_o have_v volatile_a salt_n but_o it_o must_v be_v such_o as_o exceed_v our_o own_o or_o other_o animal_n in_o activity_n briskness_n etc._n etc._n by_o reason_n of_o quantity_n or_o quality_n or_o both_o that_o it_o may_v tickle_v up_o excite_v and_o cause_v a_o fine_a and_o agreeable_a ovation_n or_o glow_v in_o our_o spirit_n which_o as_o be_v show_v be_v very_o pleasant_a as_o in_o the_o case_n of_o sem._n viril_n especial_o when_o agitate_a by_o warmth_n frication_n or_o such_o actuate_a cause_n second_o it_o manifest_o appear_v that_o the_o volatile_a salt_n of_o opium_n exceed_v we_o in_o activity_n briskness_n etc._n etc._n 1._o by_o its_o exulcerate_v or_o blister_v quality_n especial_o if_o it_o be_v very_o good_a opium_n 2._o by_o its_o psilothrick_n quality_n to_o cause_v the_o hair_n to_o shed_v 3._o by_o its_o irritate_v to_o venery_n in_o so_o eminent_a a_o degree_n as_o cantharides_n bee_n pismire_n etc._n etc._n do_v and_o even_o beyond_o the_o ordinary_a course_n of_o sem._n virile_a which_o be_v most_o saturate_v with_o volatile_a salt_n of_o any_o part_n of_o the_o animal_n as_o appear_v by_o its_o dissolution_n like_o opium_n in_o watery_a menstruum_n its_o rank_a smell_n its_o titillate_v to_o venery_n its_o weight_n etc._n etc._n which_o be_v much_o the_o same_o with_o that_o of_o opium_n both_o sink_v in_o water_n etc._n etc._n 4._o by_o its_o great_a irritation_n to_o make_v water_n like_o cantharides_n bee_n pismire_n millepedes_n etc._n etc._n when_o it_o be_v take_v in_o a_o good_a quantity_n or_o often_o 5._o by_o its_o cause_v vomit_n in_o a_o very_a severe_a manner_n which_o it_o will_v not_o do_v without_o a_o very_a poignant_a volatile_a salt_n 6._o by_o its_o cause_v such_o violent_a itch_n in_o the_o skin_n especial_o if_o take_v in_o any_o quantity_n after_o it_o have_v pass_v all_o digestion_n and_o concoction_n and_o 7._o by_o its_o cause_v acrimonious_a sweat_v after_o it_o have_v pass_v those_o digestion_n and_o concoction_n 8._o by_o its_o cause_v a_o very_a pleasant_a sensation_n at_o stomach_n far_o above_o any_o flesh_n jelly_n or_o any_o animal_n nutriment_n 9_o by_o its_o offend_v the_o eye_n so_o much_o by_o its_o acrimony_n as_o mustard_n onion_n horse_n radish_n etc._n etc._n do_v 10._o by_o its_o very_a pungent_a and_o acrimonious_a taste_n above_o all_o flesh_n or_o fish_n 11._o by_o its_o very_a rank_n and_o vehement_a scent_n equal_a to_o if_o not_o exceed_v that_o of_o semen_n virile_a 12._o by_o its_o chemical_a analysis_n whereby_o it_o afford_v a_o very_a acrimonious_a volatile_a salt_n in_o great_a plenty_n which_o helmont_n wedelius_n and_o other_o do_v confirm_v therefore_o it_o be_v also_o past_a doubt_n that_o the_o volatile_a salt_n of_o opium_n be_v more_o active_a acrimonious_a and_o titillate_v than_o those_o in_o our_o membrane_n or_o in_o sem._n virile_a itself_o but_o see_v it_o be_v not_o volatile_a salt_n alone_o as_o be_v show_v which_o agree_v only_o with_o one_o of_o the_o active_a principle_n of_o our_o membrane_n and_o may_v be_v and_o be_v of_o itself_o too_o acrimonious_a and_o rude_a for_o the_o membrane_n without_o its_o be_v sweeten_v up_o and_o smooth_v into_o a_o more_o gentle_a and_o please_a agreeableness_n by_o oily_a part_n we_o must_v see_v whether_o it_o be_v not_o also_o oily_a or_o sulphureous_a and_o consequent_o a_o sal-volatile-oleosum_a agree_v in_o both_o the_o active_a principle_n of_o our_o membrane_n that_o it_o may_v thereby_o be_v the_o more_o delectable_a gentle_a and_o agreeable_a three_o it_o be_v very_o obvious_a and_o evident_a that_o opium_n be_v sulphureous_a 1._o because_o the_o juice_n of_o the_o poppy_n whereof_o it_o be_v make_v be_v of_o itself_o when_o it_o drop_n out_o of_o the_o incision_n milkwhite_a which_o colour_n in_o liquid_n especial_o the_o juice_n of_o plant_n proceed_v from_o sulphureous_a particle_n mix_v with_o water_n or_o phlegm_n as_o milk_n emulsion_n chyle_n cinnamon_n water_n and_o the_o tincture_n of_o all_o sulphureous_a thing_n drop_v into_o water_n do_v evince_n 2._o because_o it_o be_v inflammable_a for_o nothing_o be_v so_o but_o what_o be_v sulphureous_a 3._o because_o opium_n will_v soften_v with_o a_o dry_a warmth_n which_o all_o and_o only_o sulphureous_a thing_n will_v do_v as_o all_o rosin_n tallow_n pitch_v turpentine_n oil_n and_o such_o sulphureous_a thing_n 4._o because_o it_o be_v very_o bitter_a and_o that_o oleose_a particle_n be_v always_o as_o dr._n grow_v and_o silvius_n true_o say_v one_o ingredient_n of_o a_o bitter_a taste_n 5._o it_o be_v tawny_a colour_n do_v also_o as_o be_v say_v according_a to_o dr._n grow_v argue_v much_o sulphur_n 6._o it_o be_v hot_a taste_n prove_v the_o same_o for_o a_o proper_a hot_a taste_n be_v from_o sulphur_n as_o the_o bite_n or_o pungent_a be_v from_o volatile_a salt_n 7._o because_o of_o its_o pungent_a and_o strong_a smell_n which_o denote_v sulphur_n 8._o it_o be_v be_v so_o dissolvable_a as_o it_o be_v in_o spirit_n of_o wine_n brandy_n and_o other_o sulphureous_a menstruum_n prove_v the_o same_o 9_o it_o be_v dissolve_v quality_n argue_v that_o it_o have_v the_o same_o principle_n with_o our_o skin_n and_o flesh_n which_o be_v oleose_v as_o well_o as_o salino-volatile_a and_o that_o nothing_o be_v a_o complete_a dissolver_n but_o such_o as_o have_v both_o because_o agreeableness_n in_o principle_n be_v the_o basis_n of_o dissolution_n as_o you_o see_v in_o menstruum_n and_o the_o thing_n therein_o dissolve_v there_o be_v no_o good_a kind_a or_o complete_a dissolvent_a of_o our_o flesh_n etc._n etc._n but_o what_o participate_v of_o both_o because_o otherwise_o there_o will_v be_v a_o disagreement_n in_o one_o respect_n 10._o it_o appear_v by_o autopsie_n upon_o the_o chemical_a analysis_n of_o opium_n etc._n etc._n that_o it_o have_v a_o very_a considerable_a quantity_n of_o sulphur_n 11._o so_o if_o you_o only_o dissolve_v it_o in_o water_n you_o will_v find_v much_o sulphureous_a substance_n undissolved_a at_o the_o bottom_n 12._o all_o or_o most_o of_o the_o modern_a author_n attribute_v its_o operation_n to_o sulphur_n agree_v that_o it_o be_v well_o impregnate_v therewith_o therefore_o opium_n consist_v very_o much_o as_o to_o its_o active_a principle_n of_o a_o sal-volatile-sulphureum_a but_o still_o this_o do_v not_o complete_a a_o most_o agreeable_a sal-volatile-oleosum_a 1._o because_o it_o may_v be_v a_o sal-volatile-resinosum_a and_o yet_o be_v a_o sal-volatile-sulphureum_a 2._o if_o it_o be_v a_o sal-volatile-oleosum_a the_o oil_n and_o the_o volatile_a salt_n may_v be_v so_o disjoin_v as_o not_o to_o conspire_v and_o cooperate_v to_o please_v the_o membrane_n but_o act_n separately_z as_o oil_n and_o volatile_a salt_n give_v out_o of_o divers_a
spoon_n and_o cause_n no_o more_o effect_n than_o oil_n of_o olive_n and_o spirit_n of_o sal_fw-la amenoniack_a take_v inward_o one_o act_v too_o soft_o lazy_o and_o greasy_o to_o cause_v any_o brisk_a and_o agreeable_a ovation_n of_o the_o spirit_n and_o the_o other_o too_o rude_o sting_v the_o membrane_n therefore_o we_o must_v proceed_v in_o our_o enquiry_n four_o opium_n have_v a_o sort_n of_o resinous_n sulphur_n that_o be_v loose_a and_o not_o unite_v with_o the_o volatile_a salt_n which_o plain_o appear_v 1._o because_o if_o you_o dissolve_v opium_n in_o water_n cold_a or_o hot_a or_o any_o watery_a menstruum_fw-la you_o will_v find_v a_o good_a quantity_n of_o rosin_n undissolved_a at_o bottom_n while_o the_o volatile_a salt_n be_v all_o or_o most_o dissolve_v in_o the_o water_n especial_o if_o the_o water_n be_v often_o repeat_v and_o quite_o separate_v from_o the_o resinous_n part_v which_o subside_v without_o any_o more_o trouble_n which_o show_v that_o the_o volatile_a salt_n and_o it_o be_v not_o combine_v but_o in_o a_o very_a loose_a and_o distinct_a manner_n 2._o because_o if_o you_o first_o dissolve_v opium_n in_o spirit_n of_o wine_n which_o imbibe_v the_o rosin_n it_o be_v easy_o again_o precipitate_v by_o plain_a water_n leave_v behind_o it_o all_o or_o most_o of_o the_o volatile_a salt_n in_o the_o form_n of_o a_o red_a tincture_n in_o the_o menstruum_fw-la as_o it_o do_v also_o in_o the_o former_a case_n note_v that_o the_o resinous_n part_n of_o opium_n have_v no_o effect_n as_o a_o opiate_n for_o if_o it_o be_v well_o wash_v with_o water_n as_o be_v say_v it_o have_v no_o operation_n of_o that_o kind_n or_o so_o little_a that_o it_o be_v not_o worth_a the_o mind_v but_o all_o the_o virtue_n specific_a taste_n smell_v etc._n etc._n be_v carry_v away_o in_o that_o red_a tincture_n which_o have_v all_o the_o good_a effect_n of_o opium_n as_o experience_n assure_v we_o 3._o because_o if_o opium_n be_v very_o much_o torrefy_v most_o of_o the_o volatile_a salt_n be_v evaporate_v and_o with_o it_o most_o if_o not_o all_o the_o virtue_n of_o opium_n but_o the_o rosin_n remain_v as_o a_o deadish_a stuff_n in_o respect_n of_o the_o good_a effect_n of_o opium_n though_o it_o be_v as_o shall_v be_v prove_v the_o producer_n of_o the_o ill_a effect_n thereof_o therefore_o this_o rosin_n must_v be_v whole_o reject_v five_o the_o red_a tincture_n aforesaid_a have_v all_o or_o most_o of_o the_o volatile_a salt_n in_o it_o 1._o because_o water_n be_v the_o proper_a menstruum_fw-la for_o saline_n thing_n and_o that_o the_o tincture_n reduce_v to_o a_o extract_n give_v very_o much_o in_o moist_a wether_n which_o quality_n it_o must_v have_v from_o the_o volatile_a salt_n because_o it_o have_v very_o little_o fix_v salt_n 2._o because_o the_o specific_a bitterness_n which_o proceed_v from_o volatile_a salt_n and_o oily_a part_n be_v whole_o in_o that_o red_a tincture_n 3._o because_o that_o tincture_n have_v also_o the_o specific_a rankness_n of_o smell_n that_o the_o volatile_a salt_n as_o be_v show_v give_v the_o opium_n by_o the_o help_n of_o some_o oily_a part_n 4._o because_o that_o tincture_n reduce_v to_o a_o extract_n have_v the_o bite_a taste_n of_o opium_n which_o as_o be_v show_v proceed_v from_o its_o volatile_a salt_n 5._o because_o that_o extract_n incides_fw-la discuss_n resolve_n be_v psilothrick_n titillate_n to_o venery_n cause_v itch_n in_o the_o skin_n acrimonious_a sweat_v etc._n etc._n all_o which_o be_v as_o be_v show_v the_o effect_n of_o volatile_a salt_n but_o what_o need_v i_o insist_v so_o much_o upon_o its_o effect_n to_o prove_v it_o when_o 6._o it_o appear_v by_o crystalization_n of_o the_o say_a tincture_n after_o it_o have_v be_v evaporate_v to_o a_o due_a degree_n that_o it_o contain_v the_o volatile_a salt_n in_o it_o which_o in_o a_o cool_a place_n shoot_v to_o elegant_a crystal_n and_o that_o 7._o it_o be_v find_v therein_o by_o chemical_a operation_n by_o fire_n six_o the_o say_a tincture_n be_v oleose_v 1._o because_o the_o redness_n of_o the_o tincture_n must_v be_v from_o oily_a part_n for_o pure_a sincere_a volatile_a salt_n give_v no_o such_o tincture_n 2._o because_o it_o be_v bitter_a one_o ingredient_n of_o which_o taste_n be_v ever_o oily_a part_n as_o be_v say_v 3._o because_o of_o its_o rank_a smell_n like_o sem._n viril_n which_o prove_v it_o to_o be_v sulphureous_a for_o the_o volatile_a salt_n alone_o have_v only_o a_o quick_a smell_n or_o urinous_a at_o far_a 4._o because_o it_o be_v of_o a_o hot_a taste_n when_o reduce_v to_o a_o extract_n which_o heat_v of_o taste_n consider_v distinct_o from_o its_o pungent_a or_o bite_a taste_n must_v be_v from_o sulphureous_a or_o oily_a part_n 5._o because_o spirit_n of_o wine_n and_o other_o spirituosulphureous_a menstruum_n do_v ready_o dissolve_v it_o when_o reduce_v to_o a_o extract_n 6._o because_o the_o extract_n soften_v with_o dry_a warmth_n as_o sulphureous_a or_o oily_a thing_n do_v 7._o because_o a_o true_a sal-volatile-oleosum_a wherein_o the_o volatile_a salt_n and_o oily_a part_n be_v intimate_o combine_v as_o you_o find_v in_o all_o blood_n tincture_n of_o several_a plant_n that_o have_v such_o a_o sal-volatile-oleosum_a be_v red_a 8._o because_o it_o can_v not_o otherwise_o so_o fine_o please_v the_o membrane_n cause_n sleep_n compose_v the_o spirit_n etc._n etc._n if_o it_o be_v all_o volatile_a salt_n which_o be_v whole_o pungent_a and_o acrimonious_a mighty_o oppose_v sleep_n and_o cause_v a_o great_a stir_n in_o the_o blood_n and_o spirit_n but_o as_o i_o say_v as_o to_o its_o volatile_a salt_n what_o need_v i_o insist_v upon_o its_o effect_n when_o 10._o it_o be_v inflammability_n after_o it_o be_v reduce_v to_o a_o extract_n and_o dry_v put_v it_o out_o of_o all_o question_n and_o that_o 11._o a_o oil_n may_v be_v separate_v from_o the_o volatile_a salt_n though_o not_o without_o trouble_n because_o that_o as_o be_v requisite_a to_o complete_a it_o in_o the_o high_a degree_n seven_o the_o oily_a part_n and_o volatile_a salt_n be_v very_o intimate_o and_o strict_o combine_v as_o fair_o appear_v 1._o by_o the_o difficulty_n to_o separate_v they_o 2._o by_o the_o redness_n of_o the_o tincture_n as_o in_o blood_n etc._n etc._n for_o when_o oily_a or_o sulphureous_a particle_n be_v loose_a therein_o they_o make_v either_o a_o white_a colour_n as_o the_o rosin_n do_v in_o the_o drop_n that_o fall_v out_o of_o the_o incision_n in_o the_o head_n of_o the_o poppy_n which_o be_v milk_n white_a or_o leave_v the_o volatile_a spirit_n perspicuous_a as_o in_o a_o sort_n of_o artificial_a sal._n volatile-oleosum_a that_o be_v sell_v at_o the_o apothecary_n shop_n in_o london_n 3._o because_o it_o impart_v its_o tincture_n which_o depend_v upon_o both_o to_o all_o menstruum_n 4._o because_o it_o impart_v its_o virtue_n which_o depend_v upon_o both_o to_o all_o menstruum_n 5._o because_o it_o impart_v its_o specific_a smell_n which_o depend_v upon_o both_o to_o all_o menstruumt_v 6._o because_o it_o impart_v its_o specific_a hot_a and_o bite_a taste_n which_o depend_v upon_o both_o the_o oily_a and_o volatile_a particle_n to_o all_o menstruum_n 7._o because_o it_o will_v hold_v its_o virtue_n many_o year_n which_o it_o can_v not_o if_o the_o volatile_a salt_n and_o oily_a part_n be_v not_o very_o strict_o combine_v 8._o because_o that_o notwithstanding_o the_o digestion_n at_o stomach_n it_o have_v hold_v its_o specific_a virtue_n smell_v and_o taste_n after_o it_o have_v be_v in_o it_o 4_o 5_o 6_o 7_o 8_o 9_o 10_o 11_o 12_o 18_o or_o more_o hour_n as_o appear_v by_o its_o operate_n so_o long_o and_o afteward_n its_o be_v vomit_v up_o with_o the_o same_o taste_n and_o smell_v that_o it_o have_v at_o first_o than_o which_o there_o can_v be_v a_o great_a argument_n 9_o because_o it_o have_v be_v carry_v off_o by_o stool_n which_o have_v its_o specific_a smell_n after_o many_o hour_n remain_v in_o the_o stomach_n 10._o because_o its_o operation_n in_o general_n last_v long_o charas_fw-la mention_n one_o that_o it_o operate_v with_o for_o about_o 30_o hour_n and_o wedelius_n another_o who_o opium_n cause_v to_o vomit_v constant_o about_o 18_o hour_n after_o it_o be_v take_v 11._o because_o it_o have_v its_o effect_n upon_o the_o venereal_a membrane_n after_o it_o have_v pass_v the_o digestion_n at_o stomach_n the_o effect_n of_o the_o choler_n and_o succus_fw-la pancreatus_fw-la in_o the_o duodenum_fw-la be_v strain_v through_o the_o coat_n of_o the_o intestine_n into_o the_o lacteal_v and_o through_o the_o glandule_n of_o the_o mesentery_n mix_v and_o circulate_v with_o the_o blood_n etc._n etc._n 12._o because_o after_o all_o that_o it_o have_v its_o effect_n upon_o the_o skin_n by_o cause_v a_o itch_a therein_o 13._o because_o it_o not_o only_a cause_n acrimonious_a sweat_v but_o such_o as_o evident_o smell_v thereof_o
be_v repute_v opiate_n borellus_n speak_v of_o a_o soporiferous_a aura_n that_o proceed_v from_o one_o thumb_n cure_v by_o a_o caustick_a i_o have_v read_v of_o a_o cataphora_fw-it from_o worm_n a_o soporiferous_a fume_v from_o the_o womb_n and_o very_o many_o such_o sort_n of_o instance_n which_o thing_n be_v now_o easy_o conceive_v for_o it_o be_v but_o suppose_v a_o fume_v of_o the_o nature_n of_o sem._n animale_a or_o its_o aura_n for_o i_o can_v no_o long_o doubt_v but_o it_o be_v a_o opiate_n and_o it_o will_v have_v much_o the_o same_o effect_n with_o opium_n if_o it_o be_v fit_a to_o use_v it_o after_o the_o same_o manner_n have_v show_v 1._o which_o be_v the_o predominant_a active_a principle_n in_o opium_n and_o how_o combine_v etc._n etc._n 2._o which_o of_o they_o produce_v the_o usual_a and_o laudable_a effect_n of_o opium_n and_o why_o in_o general_a i_o come_v now_o to_o the_o three_o particular_a viz._n to_o show_v iii_o which_o of_o they_o produce_v its_o ill_a effect_n and_o why_o it_o be_v ill_a effect_n be_v these_o viz._n nauseas_fw-la vomit_n which_o be_v general_o very_o dismal_a with_o great_a distress_n and_o sometime_o dangerous_a swim_v in_o the_o head_n hiccough_n distress_n anxiety_n convulsion_n faint_n leipothymy_n syncopes_fw-la etc._n etc._n 1._o note_v that_o its_o grievous_a effect_n be_v at_o or_o about_o the_o region_n of_o the_o stomach_n or_o particular_o the_o mouth_n or_o pit_n thereof_o or_o thence_o arise_v by_o consent_n 2._o note_v that_o see_v there_o be_v nothing_o so_o good_a but_o may_v cause_v evil_a effect_n in_o a_o excessive_a quantity_n this_o enquiry_n be_v more_o proper_o what_o principle_n or_o principle_n of_o opium_n do_v cause_n those_o ill_a effect_n in_o a_o ordinary_a do_v for_o what_o will_v in_o a_o moderate_a do_v will_v be_v sure_a cause_v they_o in_o a_o excessive_a do_v 3._o note_v that_o all_o the_o constant_a effect_n of_o opium_n as_o you_o may_v observe_v in_o the_o enumeration_n thereof_o in_o the_o four_o chapter_n be_v good_a and_o laudable_a effect_n it_o follow_v therefore_o that_o the_o bad_a be_v accidental_a 1._o it_o be_v not_o the_o earthy_a or_o phlegmatic_a part_n of_o opium_n that_o cause_v those_o ill_a effect_n because_o they_o be_v passive_a principle_n and_o consequent_o have_v not_o such_o a_o power_n beside_o that_o they_o be_v know_v to_o be_v innocent_a 2._o opium_n have_v all_o those_o ill_a effect_n when_o both_o the_o earthy_a and_o phlegmatic_a part_n be_v separate_v from_o it_o as_o when_o a_o extract_v of_o well_o torrefy_v opium_n be_v make_v in_o spirit_n of_o wine_n for_o by_o that_o mean_v the_o phlegmatic_a part_n be_v dry_v up_o and_o the_o earthy_a part_n subside_o and_o be_v separate_v yea_o such_o extract_v make_v by_o spirit_n of_o wine_n do_v cause_n those_o evil_a effect_n rather_o more_o than_o crude_a opium_n with_o its_o earth_n and_o phlegm_n in_o it_o as_o experience_n assure_v we_o and_o reason_n will_v plain_o confirm_v by_o and_o by_o however_o fond_a the_o world_n be_v of_o such_o preparation_n 3._o it_o be_v evident_a from_o the_o premise_n that_o the_o sal-volatile-oleosum_a of_o opium_n can_v cause_v those_o vomit_n hiccough_n etc._n etc._n for_o they_o be_v the_o effect_n of_o grievous_a sensation_n at_o stomach_n but_o the_o sal-volatile-oleosum_a cause_n a_o most_o agreeable_a and_o please_a sensation_n at_o stomach_n 4._o nothing_o quiet_v vomit_n convulsion_n â—coughs_n etc._n etc._n more_o than_o that_o sal-volatile-oleosum_a of_o opium_n 5._o experience_n inform_v we_o that_o the_o sal-volatile-oleosum_a of_o opium_n separate_v from_o all_o other_o part_n and_o principle_n thereof_o never_o cause_v such_o evil_a effect_n as_o i_o and_o another_o physician_n in_o london_n can_v testify_v as_o do_v also_o le_fw-fr mort_fw-fr in_o the_o most_o learned_a dr._n love_n collectanea_fw-la where_o he_o say_v of_o such_o a_o preparation_n thereof_o as_o contain_v only_o the_o sal-volatile-oleosum_a that_o nunquam_fw-la anxietates_fw-la circa_fw-la praecordia_fw-la aut_fw-la phantasias_fw-la conciliat_fw-la that_o be_v it_o never_o cause_v anxiety_n about_o the_o mouth_n of_o the_o stomach_n etc._n etc._n for_o that_o be_v most_o proper_o to_o be_v understand_v by_o praecordia_fw-la wedelius_n testify_v the_o like_a of_o such_o another_o preparation_n and_o so_o do_v several_a author_n though_o they_o do_v not_o in_o the_o least_o know_v why_o but_o only_o by_o experience_n 6._o it_o be_v fix_v salt_n be_v innocent_a in_o its_o nature_n and_o but_o the_o 32d_o part_n of_o opium_n which_o be_v too_o inconsiderable_a in_o a_o ordinary_a moderate_a do_v to_o cause_v any_o sensible_a effect_n it_o follow_v therefore_o that_o be_v must_v be_v the_o resinous_n part_n of_o opium_n which_o it_o have_v in_o a_o considerable_a quantity_n that_o must_v cause_v those_o ill_a effect_n this_o manifest_o appear_v 1._o because_o a_o tincture_n of_o opiam_fw-la in_o water_n which_o take_v up_o none_o of_o the_o rosin_n but_o let_v it_o fall_v into_o the_o bottom_n never_o cause_v any_o such_o ill_a effect_n which_o it_o do_v not_o also_o if_o reduce_v to_o a_o extract_v by_o evaporation_n yet_o have_v they_o all_o the_o usual_a good_a effect_n of_o opium_n 2._o wedelius_n in_o his_o opiolog_n assure_v the_o same_o of_o the_o like_a preparation_n in_o phlegm_n of_o distil_a vinegar_n l._n 2._o sect._n 1_o c._n 5._o p._n 92._o 3._o a_o extract_v of_o opium_n in_o spirit_n of_o wine_n do_v often_o cause_v those_o ill_a effect_n and_o no_o other_o preparation_n cause_v they_o as_o often_o wedelius_n ibid._n a_o laudano_n opiato_fw-it cum_fw-la spiritu_fw-la vini_n correcto_fw-la solum_fw-la ferâ—_n observavimus_fw-la ortos_fw-la vomitus_fw-la a_o nostro_fw-la vero_fw-la quod_fw-la cum_fw-la phlegmate_fw-it aceti_fw-la distillati_fw-la fieri_fw-la diximus_fw-la nunquam_fw-la vomitum_fw-la vel_fw-la nauseam_fw-la saltem_fw-la contigisse_fw-la meminimus_fw-la that_o be_v we_o have_v observe_v vomit_n almost_o only_o from_o laudanum_n prepare_v with_o spirit_n of_o wine_n but_o never_o any_o vomit_v or_o nausea_n from_o that_o prepare_v in_o phlegm_n of_o distil_a vinegar_n which_o he_o confirm_v l._n 1._o sect_n 2._o c._n 4._o p._n 62._o saying_n in_o latin_a that_o a_o curious_a observation_n be_v to_o be_v note_v by_o which_o it_o appear_v that_o a_o extract_v of_o opium_n with_o spirit_n of_o wine_n show_v more_o narcotick_a force_n by_o which_o he_o mean_v that_o it_o cause_v more_o ill_a effect_n than_o prepare_v in_o distil_a vinegar_n whereas_o that_o in_o spirit_n of_o wine_n have_v nothing_o more_o in_o it_o than_o that_o in_o vinegar_n beside_o the_o râ—sinous_n part_n therefore_o these_o do_v cause_n all_o the_o mischief_n note_v also_o that_o a_o extract_v in_o spirit_n of_o wine_n have_v in_o it_o quantity_n for_o quantity_n more_o of_o the_o râ—sinous_n part_v than_o crude_a oplum_fw-la both_o because_o the_o earthy_a part_n that_o help_v to_o make_v up_o the_o bulk_n be_v take_v away_o in_o that_o preparation_n and_o because_o the_o 〈◊〉_d of_o wine_n imbibe_v the_o rosin_n more_o greedy_o than_o other_o principle_n of_o the_o opium_n so_o that_o every_o do_v must_v in_o proportion_n have_v much_o more_o rosin_n in_o it_o than_o crude_a opium_n therefore_o it_o be_v no_o wonder_n that_o it_o cause_v those_o ill_a effect_n more_o frequent_o since_o the_o rosin_n be_v most_o certain_o the_o cause_n thereof_o as_o have_v be_v and_o shall_v be_v more_o full_o and_o beyond_o all_o contradiction_n prove_v yet_o be_v this_o the_o preparation_n boast_v of_o by_o the_o blind_a and_o inadvertent_n world_n it_o will_v amaze_v nay_o terrify_v a_o man_n to_o see_v what_o great_a care_n be_v take_v to_o be_v sure_a to_o render_v opium_n mischievous_a by_o solicitous_o use_v spirit_n of_o wine_n in_o extract_a laudanum_n and_o then_o and_o not_o till_o then_o they_o boast_v of_o the_o preparation_n as_o charas_fw-la and_o very_o many_o other_o do_v calling_z it_o not_o without_o great_a ostentation_n and_o desperate_a folly_n their_o laudanum_n may_v it_o be_v they_o and_o none_o other_o a_o turk_n will_v be_v a_o madman_n to_o use_v it_o for_o crude_a opium_n because_o it_o have_v much_o more_o of_o the_o pernicious_a principle_n in_o it_o it_o be_v the_o common_a and_o much_o esteem_v way_n first_o to_o extract_v it_o out_o of_o water_n and_o then_o it_o be_v very_o good_a laudable_a and_o innocent_a but_o think_v nothing_o worth_a till_o they_o extract_v the_o rosin_n that_o be_v all_o leave_v behind_o by_o the_o water_n in_o spirit_n of_o wine_n and_o add_v it_o to_o the_o other_o then_o do_v they_o with_o great_a authority_n praise_v it_o that_o be_v when_o they_o have_v wise_o add_v the_o poison_n to_o the_o panacea_fw-la it_o be_v as_o if_o they_o add_v ratsbane_n to_o a_o cordial_n and_o not_o think_v the_o cordial_a worthy_a commendation_n till_o they_o have_v do_v so_o 4._o it_o appear_v that_o the_o rosin_n be_v
hitherto_o but_o meet_v groundless_a and_o fantastic_a imagination_n objection_n some_o may_v say_v for_o the_o folly_n of_o the_o world_n be_v great_a why_o shall_v not_o a_o extract_v out_o of_o spirit_n of_o wine_n be_v good_a for_o since_o wine_n correct_v it_o much_o more_o shall_v spirit_n of_o wine_n do_v it_o by_o its_o more_o active_a sulphureous_a spirit_n answer_n so_o it_o will_v if_o you_o pour_v it_o upon_o it_o in_o the_o stomach_n or_o a_o digest_v pot_n for_o than_o it_o will_v much_o contribute_v to_o its_o division_n digestion_n and_o take_v off_o its_o viscidity_n as_o spirit_n of_o wine_n do_v in_o any_o vessel_n wherein_o you_o pour_v it_o upon_o rosin_n but_o it_o be_v quite_o another_o matter_n when_o reduce_v and_o rounit_v into_o the_o form_n of_o a_o extract_v again_o and_o all_o the_o spirit_n of_o wine_n evaporate_v or_o otherwise_o separate_v from_o it_o for_o then_o the_o resinous_n part_n be_v in_o statu_fw-la quo_fw-la of_o coalescence_n and_o want_v to_o be_v separate_v by_o wine_n or_o spirit_n of_o wine_n lixivial_o yolk_n of_o a_o egg_n etc._n etc._n as_o much_o as_o ever_o obj._n it_o may_v be_v say_v that_o the_o rosin_n of_o opium_n be_v but_o as_o other_o rosin_n therefore_o why_o shall_v it_o offend_v so_o much_o in_o the_o case_n of_o opium_n ans._n for_o three_o very_a manifest_a reason_n 1._o that_o it_o be_v a_o rosin_n of_o a_o peculiar_a clamminess_n and_o viscidity_n 2._o that_o it_o have_v acrimony_n in_o it_o as_o appear_v by_o its_o purge_v quality_n if_o it_o be_v give_v in_o any_o quantity_n and_o that_o the_o stomach_n dissolve_v it_o as_o be_v show_v 3._o that_o it_o be_v join_v with_o the_o pungent_a particle_n of_o the_o volatile_a salt_n of_o the_o opium_n which_o when_o it_o stick_v to_o the_o stomach_n it_o hold_v to_o it_o tear_v it_o too_o long_a and_o continual_o with_o those_o point_n upon_o the_o same_o part_n which_o must_v cause_v distress_n and_o vomit_n in_o weak_a stomach_n that_o can_v digest_v it_o and_o that_o sometime_o to_o no_o purpose_n whereupon_o follow_v convulsion_n hiccough_n etc._n etc._n and_o all_o endeavour_n fall_v a_o yield_v or_o succumbency_n follow_v by_o faint_n syncopes_fw-la leipothymy_n etc._n etc._n and_o sometime_o death_n itself_o for_o it_o must_v be_v a_o most_o grievous_a thing_n to_o be_v so_o continual_o sting_v in_o the_o same_o part_n of_o the_o most_o sensile_a membrane_n of_o the_o stomach_n without_o remedy_n or_o redress_n if_o some_o have_v die_v of_o a_o little_a gum_n ammoniacum_n or_o sagapenum_n stick_v to_o the_o intestinum_fw-la rectum_fw-la or_o colon_n which_o be_v the_o sink_v of_o the_o body_n and_o fit_v for_o and_o use_v to_o bear_v all_o faeces_fw-la and_o trash_n much_o more_o must_v the_o nice_a and_o exquisite_o dispose_v membrane_n at_o stomach_n be_v grieve_v by_o such_o point_a rosin_n as_o that_o of_o opium_n stick_v to_o some_o part_n thereof_o beside_o that_o the_o stomach_n do_v peculiarly_a hate_n and_o loath_a that_o any_o thing_n how_o gentle_a soever_o shall_v stay_v too_o long_o in_o it_o which_o create_v frequent_a and_o sad_a disturbance_n in_o such_o who_o stomach_n be_v relax_v as_o it_o be_v also_o in_o the_o case_n of_o opium_n and_o not_o in_o due_a time_n discharge_v themselves_o of_o the_o grieve_v matter_n therefore_o such_o as_o be_v most_o trouble_v with_o those_o dismal_a symptom_n after_o resinous_n opium_n be_v people_n that_o have_v fine_a texture_n and_o ill_a digestion_n with_o who_o it_o must_v and_o do_v deal_v for_o a_o good_a while_n as_o a_o pleaser_n of_o the_o stomach_n till_o the_o indigestible_a rosin_n that_o be_v stick_v to_o it_o do_v therefore_o and_o because_o it_o hold_v the_o point_n of_o the_o volatile_a salt_n so_o tedious_o and_o importunate_o to_o one_o parâ—_n grievous_o teaz_v and_o urge_v the_o stomach_n to_o vomit_v etc._n etc._n which_o it_o do_v in_o some_o soon_o in_o other_o late_a according_a to_o their_o respective_a disposition_n of_o stomach_n hence_o it_o be_v that_o it_o operate_v pleas_o in_o some_o for_o several_a hour_n before_o it_o excite_v a_o nausea_n etc._n etc._n viz._n 3_o 4_o 5_o 6_o 7_o 8_o 9_o 10_o 11_o 12_o 13_o 14_o 15_o 16_o 17_o 18_o and_o more_o hour_n and_o in_o such_o as_o have_v a_o sturdy_a texture_n and_o strong_a digestion_n operate_v only_a pleas_o all_o the_o time_n because_o their_o sensation_n be_v not_o so_o nice_a and_o that_o they_o gradual_o digest_v the_o rosin_n which_o if_o the_o opium_n be_v give_v in_o a_o large_a do_v do_v as_o rosin_n dissolve_v be_v apt_a to_o do_v especial_o if_o they_o have_v any_o acrimony_n as_o this_o have_v turn_v into_o a_o purger_n which_o bring_v down_o ordure_n that_o smell_v of_o the_o opium_n and_o so_o the_o danger_n be_v over_o how_o common_a be_v it_o that_o vomitory_n be_v much_o subdue_v in_o some_o stomach_n turn_v to_o be_v purger_n thus_o it_o happen_v with_o dog_n that_o have_v a_o robu_v texture_n and_o strong_a digestion_n but_o such_o resinous_n opium_n deal_v severe_o with_o cat_n and_o common_o kill_v they_o you_o may_v see_v from_o the_o premise_n why_o it_o cause_v ill_a symptom_n often_o in_o woman_n and_o child_n than_o in_o man_n and_o in_o fine_a textured_a man_n than_o the_o robu_v and_o in_o such_o as_o have_v weak_a digestion_n rather_o than_o in_o they_o that_o have_v strong_a why_o it_o cause_v all_o the_o symptom_n of_o please_a sensation_n at_o first_o and_o the_o ill_a effect_n afterward_o why_o some_o have_v no_o ill_a effect_n after_o it_o even_o in_o a_o large_a quantity_n unless_o you_o will_v call_v purge_v a_o ill_a effect_n why_o such_o as_o purge_v after_o a_o great_a do_v escape_v the_o danger_n as_o dog_n etc._n etc._n why_o their_o vomit_n especial_o the_o first_o smell_v etc._n etc._n of_o the_o opium_n though_o the_o vomit_v happen_v after_o many_o hour_n why_o the_o vomit_n be_v so_o very_o tedious_a and_o severe_a viz._n because_o of_o the_o stubborn_a adherence_n of_o the_o rosin_n to_o the_o stomach_n why_o it_o operate_v so_o long_a a_o time_n in_o some_o in_o comparison_n of_o other_o viz._n by_o stay_v so_o long_o at_o stomach_n 1._o all_o which_o seem_v to_o i_o a_o good_a argument_n that_o such_o as_o die_v with_o opium_n die_v while_o it_o be_v at_o stomach_n and_o consequent_o because_o of_o the_o rosin_n which_o must_v needs_o be_v fatal_a in_o great_a dose_n see_v it_o be_v sometime_o so_o very_o grievous_a in_o dose_n of_o a_o grain_n or_o two_o that_o bring_v people_n even_o to_o death_n door_n with_o vomit_n distress_n syncopes_fw-la etc._n etc._n yea_o and_o have_v kill_v some_o even_o in_o that_o small_a quantity_n as_o i_o be_o inform_v 2._o some_o evident_o die_v while_o it_o be_v at_o stomach_n because_o they_o die_v soon_o after_o they_o vomit_v up_o somewhat_o that_o smell_v of_o it_o though_o possible_o the_o rosin_n still_o stick_v to_o it_o 3._o because_o other_o evident_o die_v of_o the_o vomit_v and_o its_o plain_a effect_n at_o stomach_n 4._o because_o they_o common_o die_v with_o a_o hiâ—eough_n 5._o man_n die_v of_o it_o within_o the_o usual_a time_n that_o it_o stay_v at_o stomach_n which_o be_v sometime_o 20_o hour_n for_o certain_a whatever_o more_o it_o may_v be_v when_o large_a dose_n be_v take_v and_o to_o i_o it_o seem_v a_o argument_n of_o its_o kill_n at_o stomach_n when_o they_o die_v after_o 20_o hour_n because_o if_o it_o do_v not_o stick_v at_o stomach_n all_o that_o time_n the_o operation_n must_v have_v be_v over_o or_o at_o least_o much_o decline_v and_o consequent_o the_o height_n of_o the_o danger_n past_a 6._o i_o can_v find_v that_o any_o have_v die_v of_o opium_n when_o the_o rosin_n be_v separate_v from_o it_o though_o i_o do_v not_o deny_v but_o that_o it_o may_v kill_v then_o as_o a_o immoderate_a quantity_n of_o wine_n have_v do_v but_o this_o i_o can_v tell_v that_o one_o do_v at_o mr._n bank_n the_o chemist_n in_o walbrook_n in_o the_o city_n of_o london_n drink_v as_o mr._n banks_n inform_v i_o a_o pint_n and_o a_o half_n of_o such_o a_o liquid_a preparation_n of_o opium_n that_o have_v the_o rosin_n separate_v from_o it_o that_o have_v the_o power_n of_o 3_o ounce_n of_o opium_n in_o it_o and_o it_o never_o harm_v nor_o discompose_v he_o but_o that_o he_o vomit_v about_o a_o hour_n after_o it_o be_v take_v whether_o he_o do_v so_o by_o reason_n of_o the_o opium_n or_o because_o the_o person_n be_v cropsick_a as_o they_o call_v it_o by_o reason_n he_o have_v drink_v much_o wine_n before_o or_o both_o i_o can_v determine_v now_o i_o hope_v that_o my_o inquisitive_a reader_n be_v full_o satisfy_v 1._o that_o opium_n do_v not_o act_n by_o a_o cold_a quality_n nor_o by_o the_o mean_n of_o fume_n nor_o any_o how_o
by_o diminish_v or_o disable_n the_o spirit_n except_o it_o be_v that_o the_o pernicious_a rosin_n may_v do_v something_o of_o that_o kind_n by_o its_o aforesaid_a ill_a effect_n but_o by_o pleasant_o affect_v the_o membrane_n at_o stomach_n venereal_a part_n etc._n etc._n 2._o that_o sleep_n be_v cause_v by_o relaxation_n and_o quiet_v the_o spirit_n 3._o that_o pleasure_n especial_o if_o intense_a and_o last_a as_o that_o by_o opium_n comfort_n enlivens_fw-la encourage_v and_o cause_v a_o ovation_n of_o the_o sensitive_a soul_n and_o spirit_n and_o displeasure_n cause_v sadness_n dejection_n etc._n etc._n 4._o how_o pleasure_n must_v cause_v complacency_n satisfaction_n content_a acquiescence_n and_o composure_n of_o the_o sensitive_a soul_n and_o spirit_n as_o grievance_n cause_v the_o contrary_n 5._o how_o pleasure_n elevate_a and_o keep_v up_o the_o spirit_n and_o cause_v a_o entire_a relaxation_n of_o the_o defensive_a and_o a_o great_a relaxation_n of_o the_o vigilative_a contraction_n which_o tire_v the_o sensitive_a soul_n must_v cause_v euphory_n or_o easy_a undergo_n of_o labour_n journey_n etc._n etc._n without_o lassitude_n as_o experience_n show_v 6._o how_o pleasure_n cause_v relaxation_n of_o all_o the_o sensile_a part_n 7._o how_o the_o say_a relaxation_n as_o in_o sleep_n do_v by_o suffer_v the_o animal_n spirit_n to_o expand_v and_o thereby_o make_v they_o unfit_a to_o carry_v impression_n smart_o which_o be_v necessary_a to_o convey_v a_o sense_n of_o pain_n for_o a_o smart_a impression_n be_v the_o very_a cause_n of_o it_o take_v away_o pain_n to_o which_o you_o may_v add_v that_o the_o sensitive_a soul_n attend_v willing_o to_o the_o sense_n of_o pleasure_n be_v divert_v from_o pain_n and_o that_o a_o sense_n of_o pain_n can_v be_v in_o the_o same_o subject_a with_o pleasure_n which_o be_v therefore_o once_o excite_v pain_n must_v disappear_v but_o that_o of_o take_v away_o all_o smartness_n of_o impression_n by_o relaxation_n be_v a_o plain_a mechanical_a cause_n 8._o how_o therefore_o all_o flux_n that_o be_v cause_v by_o or_o require_v a_o grievous_a sensation_n or_o irritation_n by_o quantity_n or_o quality_n to_o maintain_v and_o continue_v they_o by_o cause_v a_o contraction_n of_o the_o part_n to_o squeeze_v out_o the_o humour_n must_v be_v moderate_v for_o want_v of_o sensation_n upon_o such_o relaxation_n to_o irritate_fw-la the_o part_n as_o it_o happen_v in_o sleep_n or_o in_o any_o case_n where_o relaxation_n and_o thereby_o expansion_n of_o the_o animal_n spirit_n incapacitates_fw-la they_o to_o carry_v impression_n smart_o which_o be_v of_o the_o essence_n of_o pain_n as_o have_v be_v show_v 9_o how_o perspiration_n must_v be_v promote_v by_o relaxation_n which_o open_v the_o pore_n 10._o how_o that_o by_o the_o same_o mean_n sweat_v also_o must_v be_v promote_v if_o the_o body_n be_v full_a of_o moisture_n 11._o how_o opium_n or_o semen_n animale_a be_v of_o the_o same_o principle_n and_o of_o like_a principle_n with_o cantharides_n pismire_n bee_n garlick_n etc._n etc._n must_v excite_v to_o venery_n cause_n itch_n of_o the_o skin_n etc._n etc._n 12._o how_o opium_n may_v by_o too_o high_a a_o ovation_n of_o the_o spirit_n cause_n watch_v while_o pleasure_n cause_v relaxation_n etc._n etc._n may_v take_v away_o pain_n for_o relaxation_n as_o in_o sleep_n syncopes_fw-la etc._n etc._n be_v enough_o to_o take_v away_o pain_n but_o to_o sleep_v quietness_n of_o the_o spirit_n be_v also_o require_v as_o well_o as_o their_o expansion_n by_o relaxation_n so_o that_o pain_n may_v very_o well_o be_v take_v off_o without_o sleep_n as_o it_o often_o be_v by_o opium_n that_o always_o relax_n 13._o how_o the_o pleasure_n that_o opium_n cause_n be_v as_o be_v say_v by_o the_o same_o principle_n and_o therefore_o of_o the_o same_o nature_n with_o that_o which_o animal_n seed_n cause_v upon_o the_o membrane_n but_o that_o animal_n seed_n cause_v it_o only_o upon_o one_o part_n and_o opium_n upon_o the_o membrane_n of_o the_o stomach_n venereal_a part_n and_o all_o other_o in_o general_n and_o that_o only_a for_o a_o moment_n but_o this_o of_o opium_n for_o many_o hour_n by_o which_o mean_v the_o effect_n of_o relaxtion_n by_o pleasure_n come_v to_o be_v more_o remarkable_a as_o after_o much_o wine_n who_o effect_n be_v somewhat_o last_v and_o internal_a as_o that_o of_o opium_n be_v 14._o how_o the_o rosin_n of_o opium_n cause_v its_o ill_a effect_n by_o its_o indigestibleness_n adhere_v quality_n and_o tedious_a sting_a of_o the_o exquisite_o nice_a coat_n of_o the_o stomach_n by_o continual_o teaze_v and_o urge_v it_o by_o its_o actimony_n and_o acute_a volatile_a point_n or_o spiculâ—_n therefore_o have_v 1._o a_o most_o perfect_a and_o complete_a sol-volatile-oleosum_a in_o opium_n of_o the_o same_o please_a principle_n as_o to_o all_o membrane_n as_o animal_n seed_n be_v to_o the_o membrane_n of_o venus_n whereby_o they_o must_v be_v please_v tickle_v and_o relax_v 2._o a_o pernicious_a rosin_n indigestible_a stick_v and_o arm_v with_o acrimonious_a and_o sting_a point_n which_o must_v high_o offend_v the_o most_o sensile_a coat_n at_o the_o stomach_n i_o be_o now_o ready_a by_o god_n assistance_n to_o explain_v every_o phenomenon_n or_o effect_v of_o opium_n however_o amaze_a and_o mysterious_a hope_v they_o will_v not_o remain_v long_o so_o chap._n xvi_o the_o explication_n of_o the_o effect_n of_o opium_n use_v external_o its_o effect_n external_o use_v be_v of_o two_o sort_n either_o i._o as_o a_o opiate_n or_o please_a tickler_n of_o the_o membrane_n or_o ii_o as_o a_o alterative_a of_o the_o part_n that_o it_o be_v apply_v to_o first_o as_o a_o opiate_n or_o pleaser_n of_o the_o membrane_n it_o have_v the_o same_o effect_n as_o opium_n use_v internal_o and_o for_o the_o same_o reason_n therefore_o the_o cause_n of_o its_o operation_n in_o this_o case_n will_v be_v better_o see_v by_o the_o explication_n of_o its_o internal_a effect_n which_o be_v far_o more_o perfect_a complete_a and_o certain_a second_o as_o a_o alterative_a of_o the_o part_n that_o it_o be_v apply_v to_o which_o be_v the_o follow_v viz._n 1._o it_o incides_fw-la resolve_n and_o discuss_n by_o its_o point_a penetrate_a and_o volatile_a salt_n insinuate_v itself_o into_o the_o part_n and_o humour_n of_o the_o animal_n because_o its_o particle_n be_v fine_a minute_n and_o agreeable_a thereto_o as_o menstruum_n to_o the_o thing_n to_o be_v dissolve_v then_o by_o its_o volatility_n it_o discuss_n what_o it_o have_v so_o incide_v and_o resolve_v 2._o it_o mollefy_v and_o relax_n by_o its_o sal-volatile-oleosum_a so_o resolve_v the_o part_n and_o humour_n and_o thereby_o kindly_a loosen_a they_o thus_o opiate_n as_o solanum_fw-la lethale_n or_o deadly_a night_n shade_n hemlock_n mandrake_n etc._n etc._n come_v to_o be_v of_o excellent_a use_n in_o hard_a tumor_n of_o the_o spleen_n tophousness_n etc._n etc._n 3._o it_o maturate_v and_o suppurate_v for_o the_o aforesaid_a reason_n for_o nothing_o can_v better_v dispose_n towards_o maturation_n and_o suppuration_n than_o relax_v mollefy_a and_o resolve_v 4._o it_o exulcerate_v or_o cause_n blister_n or_o at_o least_o rubify_v tender_a skin_n if_o it_o be_v very_o strong_a because_o of_o its_o volatile_a salt_n as_o cantharides_n spearwort_n and_o other_o thing_n do_v upon_o the_o same_o account_n but_o this_o effect_n belong_v main_o to_o the_o true_a mastack_n or_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o drop_n from_o the_o incision_n make_v in_o the_o head_n of_o the_o poppy_n more_o especial_o the_o theban_a which_o afford_v a_o most_o powerful_a juice_n for_o exulcerate_v or_o blister_v be_v but_o a_o strong_a full_a and_o therefore_o painful_a resolution_n as_o you_o see_v by_o the_o cuticle_n upon_o blister_n resolve_v into_o a_o kind_n of_o jelly_n 5._o it_o be_v psilothrick_n for_o the_o same_o reason_n for_o while_o it_o so_o resolve_v the_o part_n it_o loosen_v the_o root_n of_o the_o hair_n and_o so_o cause_v its_o shed_n 6._o it_o hurt_v the_o eye_n because_o of_o its_o acrimony_n by_o reason_n of_o the_o volatile_a salt_n 7._o it_o cause_v itch_a in_o the_o skin_n by_o the_o titillation_n of_o the_o same_o volatile_a salt_n as_o you_o find_v by_o the_o application_n of_o squill_n and_o the_o like_a 8._o it_o excite_v venery_n by_o the_o same_o titillation_n on_o the_o veneral_a membrane_n chap._n xvii_o the_o explication_n of_o the_o effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v note_v that_o because_o opium_n have_v be_v general_o hitherto_o use_v either_o crude_a or_o with_o its_o rosin_n in_o it_o the_o effect_n of_o opium_n be_v according_o consider_v as_o common_a experience_n thereupon_o have_v give_v opportunity_n of_o observe_v they_o but_o as_o i_o proceed_v i_o shall_v show_v you_o where_o the_o resinous_n part_n of_o opium_n be_v concern_v in_o the_o effect_n 1._o it_o be_v manifest_a why_o opium_n may_v well_o
only_o in_o those_o membrane_n but_o also_o in_o the_o more_o exquisite_o dispose_v membrane_n for_o sensation_n at_o stomach_n and_o soon_o after_o all_o over_o the_o body_n 5._o it_o prevent_v and_o take_v away_o grief_n fear_v anxiety_n peevishness_n fretfulness_n etc._n etc._n for_o the_o aforesaid_a reason_n which_o cause_n a_o blithe_a gay_a and_o good_a humour_n promptitude_n courage_n etc._n etc._n for_o it_o be_v impossible_a to_o be_v gay_a and_o good_a humour_a serene_a cheerful_a courageous_a and_o magnanimous_a and_o at_o the_o same_o time_n sorrowful_a fearful_a peevish_a fretful_a etc._n etc._n if_o the_o bare_a sense_n of_o a_o ordinary_a meal_n of_o meat_n at_o stomach_n which_o cause_v but_o a_o slow_a pleasure_n in_o comparison_n with_o opium_n take_v off_o the_o peevishness_n fretfulness_n etc._n etc._n that_o the_o grievous_a sensation_n of_o hunger_n cause_n how_o much_o more_o must_v the_o intense_a and_o charm_a pleasure_n cause_v by_o opium_n that_o be_v so_o agreeable_a even_o far_o beyond_o wine_n itself_o as_o have_v be_v set_v forth_o take_v away_o all_o ill_a humour_n fretfulness_n peevishness_n etc._n etc._n obj._n but_o it_o may_v be_v say_v that_o sleepiness_n which_o depend_v also_o upon_o relaxation_n as_o the_o effect_n of_o pleasure_n do_v cause_v a_o peevish_a fretful_a humour_n as_o be_v common_o observe_v ans._n it_o be_v so_o far_o otherwise_o in_o the_o case_n of_o opium_n that_o it_o be_v quite_o contrary_a for_o 1._o the_o sleepy_a be_v not_o peevish_a unless_o you_o put_v they_o by_o some_o mean_v out_o of_o the_o pleasure_n of_o enjoy_v sleep_n or_o relaxation_n for_o if_o you_o let_v they_o alone_o they_o will_v not_o trouble_v you_o with_o peevishness_n nor_o any_o ill_a humour_n but_o it_o be_v the_o call_v they_o from_o their_o relaxed_a condition_n to_o the_o grievous_a task_n of_o contraction_n that_o vex_v they_o so_o that_o it_o be_v the_o want_n of_o continue_v under_o the_o relaxation_n that_o fret_v they_o and_o the_o more_o because_o the_o fatigue_n and_o tedium_n of_o contraction_n do_v put_v they_o upon_o the_o relief_n of_o sleep_n of_o which_o if_o disappoint_v they_o be_v much_o vex_v but_o in_o the_o case_n of_o opium_n you_o can_v so_o easy_o rob_v they_o of_o their_o pleasure_n which_o they_o carry_v continual_o within_o they_o in_o a_o uninterrupted_a manner_n unless_o some_o very_a grievous_a thing_n happen_v which_o cause_v more_o defensive_a contraction_n than_o the_o opium_n cause_v relaxation_n though_o even_o this_o also_o be_v general_o soon_o overcome_v by_o the_o pleasure_n continual_o invite_v the_o relaxation_n and_o promote_a it_o whereas_o the_o interruption_n thereof_o be_v transitory_a but_o at_o the_o worst_a it_o be_v but_o take_v more_o opium_n and_o the_o work_n be_v do_v for_o i_o observe_v that_o the_o do_v of_o opium_n must_v be_v sufficient_a to_o introduce_v such_o a_o sense_n of_o pleasure_n as_o cause_v a_o relaxation_n of_o the_o contraction_n cause_v by_o the_o grievance_n hence_o it_o be_v certain_a that_o a_o great_a pain_n require_v a_o large_a do_v of_o opium_n as_o have_v be_v intimate_v 6._o all_o know_v that_o pleasant_a diversion_n as_o music_n pleasant_a jest_n and_o story_n fine_a sight_n etc._n etc._n do_v cause_n euphory_n and_o a_o easy_a undergo_n of_o journey_n labour_n etc._n etc._n therefore_o if_o such_o interrupt_v transient_a and_o slight_a pleasure_n do_v it_o so_o much_o it_o will_v be_v easy_o grant_v i_o that_o a_o continual_a and_o more_o intense_a pleasure_n that_o be_v always_o present_a without_o any_o interruption_n or_o intermission_n as_o that_o of_o opium_n must_v cause_v a_o more_o eminent_a and_o permanent_a euphory_n proportion_v to_o the_o pleasure_n which_o cause_v relaxation_n prevent_v the_o fatigue_n or_o lassitude_n that_o be_v cause_v only_o by_o contraction_n either_o vigilative_a defensive_a or_o intentive_a as_o i_o have_v prove_v so_o that_o i_o do_v not_o conceive_v how_o the_o noctambuli_n or_o such_o as_o walk_v in_o their_o sleep_n can_v ever_o be_v tire_v if_o they_o travel_v ever_o so_o far_o if_o they_o can_v eat_v and_o drink_v because_o the_o relaxation_n of_o the_o sleep_v recruit_n they_o as_o much_o as_o they_o spend_v of_o spirit_n etc._n etc._n so_o person_n that_o cause_v such_o relaxation_n by_o opium_n and_o so_o repeat_v it_o as_o to_o maintain_v the_o relaxation_n can_v hardly_o be_v weary_a which_o be_v the_o true_a plain_a and_o mechanical_a reason_n why_o the_o turk_n and_o other_o eastern_a people_n do_v by_o the_o help_n of_o opium_n perform_v prodigious_a journey_n without_o be_v tire_v which_o may_v therefore_o in_o allusion_n to_o the_o noctambuli_n be_v call_v opiambuli_n or_o opambuli_n as_o be_v a_o kind_n of_o artificial_a noctambuli_n because_o they_o be_v much_o relax_v by_o the_o pleasure_n that_o opium_n cause_n as_o the_o other_o be_v by_o sleep_n qui_fw-la laetitiâ_fw-la aâ—iciuntur_fw-la say_v sanctorius_n nuâ—lam_n in_o itinere_fw-la defatigationem_fw-la sentiunt_fw-la that_o be_v the_o merry_a be_v not_o weary_a as_o the_o say_v be_v because_o mirth_n be_v pleasant_a cause_v relaxation_n as_o opium_n do_v in_o some_o measure_n note_v that_o as_o to_o all_o the_o forego_n serene_a and_o brisk_a effect_n a_o full_a and_o liberal_a perspiration_n which_o it_o also_o cause_n as_o will_v be_v show_v contribute_v much_o thereto_o a_o posteriori_fw-la for_o as_o fire_n burn_v slow_o and_o dull_o if_o the_o smoke_n do_v by_o any_o mean_n return_v upon_o it_o and_o very_o serene_a if_o not_o so_o it_o be_v with_o the_o flame_n of_o life_n if_o cloud_v with_o or_o clear_v from_o vapour_n by_o perspiration_n sanctor_n sect._n 7._o aph._n 17._o mâ—lancholia_fw-la superatur_fw-la liberâ_fw-la perspiratione_fw-la &_o aph._n 30._o 31._o edulia_n aperientia_fw-la gaudium_fw-la movent_fw-la that_o be_v such_o as_o open_v the_o pore_n and_o cause_n perspiration_n cause_n joy_n or_o mirth_n 7._o it_o lull_v soothe_v and_o as_o it_o be_v charm_v the_o mind_n with_o consent_n and_o acquiescence_n for_o the_o several_a reason_n couch_v in_o the_o premise_n and_o because_o the_o fine_a continual_a and_o charm_a pleasure_n of_o opium_n such_o as_o some_o glass_n of_o generous_a wine_n cause_v must_v needs_o have_v such_o a_o effect_n 8._o it_o quiet_v allay_v and_o compose_v all_o perturbation_n and_o commotion_n of_o the_o sensitive_a soul_n spirit_n etc._n etc._n 1._o because_o it_o so_o lull_v soothe_v and_o charm_n the_o sensitive_a soul_n as_o be_v aforesaid_a who_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n 2._o because_o all_o motion_n be_v by_o the_o relaxation_n proportionable_o abate_v as_o be_v demonstrate_v thus_o opium_n take_v off_o hysterick_n fit_v fever_n from_o commotion_n of_o the_o spirit_n convulsion_n stop_v hemerrhage_n or_o bleed_v &c._n &c._n 9_o it_o cause_v a_o relaxation_n of_o all_o the_o sensile_a part_n of_o the_o body_n by_o reason_n of_o the_o great_a and_o continual_a pleasure_n that_o it_o cause_n and_o how_o pleasure_n cause_v relaxation_n i_o have_v show_v in_o chap._n 14._o 10._o it_o cause_v indolence_n or_o exemption_n from_o pain_n by_o cause_v so_o high_a and_o last_a a_o pleasure_n 1._o because_o that_o pleasure_n take_v up_o the_o attention_n of_o the_o sensitive_a soul_n who_o delight_v in_o it_o 2._o because_o a_o sense_n of_o pleasure_n and_o pain_n can_v be_v at_o the_o same_o time_n in_o the_o same_o subject_a be_v they_o be_v contrary_n 3._o because_o the_o membrane_n be_v relax_v and_o the_o animal_n spirit_n expanded_a the_o impression_n of_o pain_n can_v be_v carry_v to_o the_o sensitive_a soul_n because_o they_o can_v convey_v impression_n smart_o be_v thus_o relax_v and_o expanded_a as_o have_v be_v demonstrate_v by_o the_o comparison_n of_o a_o gut_n half_n full_a of_o air_n etc._n etc._n and_o all_o impression_n of_o pain_n must_v be_v smart_n or_o else_o they_o be_v not_o impression_n of_o pain_n for_o gentle_a impression_n be_v such_o as_o belong_v to_o oil_n smooth_a and_o soft_a thing_n or_o when_o the_o animal_n spirit_n can_v hardly_o carry_v any_o impression_n but_o gentle_o as_o in_o sleep_n and_o other_o relaxation_n as_o that_o upon_o pleasure_n etc._n etc._n which_o be_v our_o case_n note_v that_o it_o will_v cause_v indolence_n without_o cause_v sleep_n because_o sleep_n require_v relaxation_n and_o quiet_a of_o the_o spirit_n but_o indolence_n require_v only_a relaxation_n as_o be_v show_v which_o always_o follow_v the_o charm_a pleasure_n of_o opium_n 11._o it_o stop_v moderate_v or_o palliate_n most_o flux_n and_o promote_v perspiration_n because_o the_o relaxation_n take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o cause_v a_o contraction_n to_o squeeze_v they_o out_o and_o that_o the_o same_o relaxation_n open_v the_o pore_n to_o let_v the_o foam_n out_o which_o pass_v by_o their_o own_o levity_n upon_o the_o open_n of_o the_o pore_n nihil_fw-la magis_fw-la say_v sanctorius_n
part_n by_o its_o relax_v the_o pore_n of_o the_o kidney_n and_o render_v the_o humour_n more_o penetrate_v in_o some_o measure_n by_o the_o volatile_a salt_n 20._o it_o cause_v a_o nausea_n by_o its_o rosin_n stick_v to_o and_o teaze_v the_o sensile_a coat_n of_o the_o stomach_n the_o reason_n why_o it_o be_v general_o so_o long_o before_o it_o cause_v a_o nausea_n or_o vomit_v be_v that_o its_o pleasure_n do_v at_o first_o prevent_v it_o till_o at_o last_o the_o stick_a rosin_n urge_v it_o by_o its_o long_a stay_n and_o vexatious_a adherence_n 21._o it_o cause_v swimmings_n in_o the_o head_n by_o consent_n when_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o you_o find_v upon_o nauseas_fw-la before_o vomit_v or_o when_o any_o thing_n do_v much_o offend_v the_o stomach_n as_o much_o drink_n or_o wine_n which_o when_o they_o have_v vomit_v those_o swimming_n cease_v 22._o it_o cause_v watch_v in_o some_o person_n who_o be_v of_o very_o movable_a spirit_n by_o actuate_a and_o stir_v their_o spirit_n by_o its_o active_a volatile_a salt_n though_o it_o do_v at_o the_o same_o time_n please_v the_o membrane_n and_o consequent_o relax_v the_o sensile_a part_n and_o thereby_o cause_n indolence_n the_o effect_n of_o relaxation_n which_o it_o also_o do_v when_o people_n keep_v themselves_o from_o sleep_n by_o voluntary_a motion_n and_o therefore_o take_v away_o pain_n even_o when_o man_n travel_v etc._n etc._n beside_o there_o be_v some_o sort_n of_o person_n that_o upon_o joy_n good_a news_n pleasure_n or_o the_o like_a be_v too_o much_o elevate_v or_o have_v a_o restless_a ovation_n of_o the_o spirit_n which_o will_v not_o suffer_v they_o to_o sleep_n though_o they_o be_v in_o a_o pleasant_a condition_n all_o the_o time_n this_o may_v be_v the_o case_n of_o some_o that_o can_v sleep_v after_o opium_n though_o they_o be_v all_o the_o time_n as_o they_o call_v it_o in_o a_o heavenly_a condition_n for_o as_o i_o have_v say_v a_o quietness_n of_o the_o spirit_n be_v requisite_a to_o cause_v sleep_n as_o well_o as_o relaxation_n but_o relaxation_n alone_o and_o thereby_o expansion_n of_o the_o spirit_n so_o that_o they_o can_v carry_v impression_n smart_o be_v sufficient_a to_o cause_v indolence_n and_o the_o pleasure_n to_o cause_v a_o heavenly_a or_o very_o pleasant_a condition_n sanctor_n stat._n med._n sect._n 7._o aph._n 28._o say_v that_o laetitia_n perseverans_fw-la per_fw-la multos_fw-la dies_fw-la somnum_fw-la impedit_fw-la persevere_v pleasure_n may_v do_v the_o same_o by_o like_a reason_n that_o be_v too_o much_o 〈◊〉_d or_o ovation_n of_o the_o spirit_n sometime_o too_o large_a a_o do_v cause_n watch_v by_o over-actuating_a and_o exciting_a the_o spirit_n medicum_fw-la vini_fw-la generosi_fw-la &_o allium_fw-la say_v sanctorius_n conciliant_fw-la somnum_fw-la &_o perspirationem_fw-la si_fw-la vero_fw-la plus_fw-la justo_fw-la sumantur_fw-la utrumque_fw-la prohibent_fw-la perspirabile_fw-la tamen_fw-la in_o sudorem_fw-la convertunt_fw-la that_o be_v a_o little_a generous_a wine_n and_o garlic_n will_v cause_v sleep_n and_o perspiration_n but_o too_o much_o hinder_v both_o yet_o they_o convert_v the_o perspirable_a matter_n to_o a_o sweat_n which_o wine_n and_o garlick_n have_v the_o nature_n of_o opiate_n and_o the_o reason_n why_o they_o sweat_v be_v the_o quantity_n of_o the_o wine_n afford_v more_o moisture_n hypocrates_n say_v 23._o a_o dubious_a state_n between_o sleep_v and_o wake_v be_v cause_v when_o the_o relaxation_n upon_o the_o pleasure_n of_o opium_n incline_v to_o sleep_v but_o the_o irreâ—uiete_a ovation_n of_o the_o spirit_n by_o the_o pleasure_n and_o titillation_n will_v hardly_o suffer_v it_o yet_o high_o please_v and_o put_v they_o in_o a_o sweet_a agreeable_a condition_n chap._n xix_o the_o explication_n of_o the_o rare_a effect_n of_o opium_n in_o a_o moderate_a do_v 1._o it_o cause_v temporary_a pulse_n of_o the_o 〈◊〉_d and_o sometime_o of_o other_o part_n by_o its_o over_o relax_v the_o part_n and_o cause_v thereby_o a_o expansion_n of_o the_o elastic_a spirit_n which_o as_o be_v demonstrate_v weaken_v their_o motion_n 2._o falter_v of_o the_o tongue_n do_v as_o in_o relaxation_n by_o drunkenness_n proceed_v from_o the_o same_o cause_n 3._o looseness_n of_o the_o low_a jaw_n as_o you_o see_v in_o the_o drowsy_a and_o drunken_a people_n be_v from_o the_o same_o relaxation_n 4._o it_o sometime_o prevent_v sweat_n by_o cause_v a_o very_a liberal_a perspiration_n as_o be_v show_v for_o as_o sanctorius_n say_v who_o shall_v know_v it_o much_o insensible_a perspiration_n and_o sweat_n can_v consist_v especial_o in_o a_o temperate_a person_n who_o eat_v and_o drink_v moderate_o therefore_o if_o you_o keep_v a_o person_n that_o sweat_v much_o at_o night_n in_o a_o free_a perspiration_n all_o day_n by_o the_o help_n of_o a_o opiate_n you_o will_v much_o lessen_v or_o total_o prevent_v the_o sweat_n at_o night_n as_o in_o consumptive_a person_n etc._n etc._n 5._o it_o cause_v abortion_n by_o relax_v the_o neck_n of_o the_o womb_n which_o also_o the_o pleasure_n of_o coition_n sometime_o do_v for_o the_o like_a reason_n and_o will_v be_v much_o more_o apt_a to_o cause_v it_o if_o it_o continue_v long_o as_o that_o of_o opium_n do_v note_v the_o inconvenience_n of_o coition_n after_o impregnation_n this_o be_v the_o great_a cause_n that_o whore_n be_v not_o apt_a to_o bear_v child_n because_o frequency_n of_o pleasure_n do_v over-relax_a the_o collum_n 〈◊〉_d 6._o it_o prevent_v abortion_n when_o fear_n terror_n or_o any_o contract_a cause_n as_o grief_n grievous_a passion_n or_o sensation_n do_v threaten_v it_o by_o its_o take_n off_o the_o contraction_n and_o grievance_n that_o cause_v it_o 7_o intumescence_n of_o the_o lip_n be_v from_o their_o relaxation_n admit_v the_o blood_n and_o humour_n into_o they_o in_o a_o plentiful_a manner_n beside_o that_o their_o laxity_n and_o the_o inadvertency_n occasion_v by_o the_o divert_v pleasure_n or_o drowsiness_n that_o follow_v let_v the_o low_a lip_n hang_v down_o careless_o as_o be_v usual_a in_o such_o case_n may_v by_o expose_v much_o more_o of_o that_o lip_n which_o be_v most_o concern_v in_o this_o effect_n make_v it_o seem_v large_a as_o a_o hang_a lip_n do_v 8._o it_o may_v cure_v a_o dropsy_n as_o dr._n wâ—llis_n do_v instance_n 1._o by_o cause_v a_o free_a perspiration_n which_o be_v much_o want_v in_o those_o case_n 2._o by_o relax_v the_o pore_n and_o make_v way_n for_o the_o humour_n to_o 〈◊〉_d 3._o by_o cause_v much_o urine_n as_o cantharides_n millepedes_n &c_n &c_n do_v upon_o the_o account_n of_o their_o volatile-salt_n with_o which_o opium_n abound_v 9_o it_o cure_v stupor_n that_o proceed_v from_o contraction_n as_o by_o cold_a etc._n etc._n by_o relax_v all_o part_n 10._o it_o cause_v anxiety_n and_o distress_n by_o the_o rosin_n stick_v and_o teaze_v the_o stomach_n 11._o vomit_n and_o hiccough_n proceed_v from_o the_o same_o cause_n 12._o convulsion_n be_v cause_v by_o the_o same_o rosin_n while_o it_o continual_o urge_v the_o stomach_n to_o grievous_a vomit_n which_o at_o last_o draw_v other_o part_n as_o the_o stomach_n usual_o do_v when_o under_o great_a grievance_n into_o violent_a contraction_n or_o convulsion_n by_o consent_n to_o endeavour_v its_o assistance_n because_o the_o defensive_a contraction_n grow_v very_o high_a by_o the_o almost_o intolerable_a and_o tedious_a grievance_n at_o stomach_n cause_v a_o mighty_a compression_n of_o the_o springy_a animal_n spirit_n by_o which_o mean_v they_o grow_v very_o forcible_a irrequiete_a and_o violent_o springy_a under_o the_o urgency_n of_o a_o enormous_a compressure_n which_o cause_v such_o convulsive_a motion_n note_v that_o such_o a_o violent_a compression_n of_o the_o animal_n spirit_n into_o a_o great_a springiness_n be_v the_o cause_n of_o the_o strength_n of_o convulsive_a motion_n so_o that_o sometime_o a_o strong_a man_n can_v hardly_o hold_v a_o child_n limb_n in_o such_o case_n 13._o syncopes_fw-la leipothymy_n and_o faint_n follow_v when_o the_o sensitive_a soul_n be_v quite_o tire_v and_o overbear_v by_o the_o fatigue_n of_o such_o distress_n vomit_n and_o defensive_a contraction_n to_o reject_v and_o excuss_v the_o say_v adhere_v and_o teaze_v rosin_n yield_v itself_o to_o rest_n and_o let_v we_o go_v the_o reign_v of_o contraction_n as_o be_v fruitless_a and_o no_o long_o endurable_a whereupon_o all_o the_o sensile_a part_n be_v relax_v in_o the_o high_a degree_n they_o thereby_o grow_v unfit_a for_o sensation_n and_o the_o animal_n spirit_n expand_v as_o far_o as_o the_o atmospherical_a compressure_n permit_v they_o so_o that_o they_o grow_v incapable_a to_o convey_v impression_n by_o which_o mean_v sense_n fail_v and_o motion_n also_o for_o the_o same_o reason_n because_o the_o animal_n spirit_n loose_v their_o springy_a endeavour_n for_o want_n of_o a_o sufficient_a compression_n to_o render_v they_o flippant_a for_o the_o purpose_n which_o be_v the_o cause_n as_o in_o sleep_n that_o sense_n
and_o motion_n fail_v together_o of_o the_o great_a perspiration_n and_o all_o other_o effect_n of_o relaxation_n in_o such_o syncopes_fw-la or_o leipothymy_n in_o a_o yet_o high_o degree_n than_o in_o sleep_n wherein_o the_o sensitive_a soul_n do_v not_o quite_o let_v go_v the_o reign_v of_o contraction_n as_o appear_v by_o the_o motion_n that_o remain_v as_o of_o the_o heart_n intestine_n etc._n etc._n though_o far_o more_o remiss_a in_o sleep_n than_o in_o a_o wake_v state_n note_v that_o such_o leipothymy_n be_v as_o be_v hint_v of_o the_o same_o nature_n as_o sleep_n be_v but_o that_o they_o be_v sudden_a more_o profound_a and_o not_o so_o usual_a natural_a and_o of_o course_n as_o sleep_n be_v which_o make_v they_o more_o amaze_a and_o surprise_v therefore_o it_o follow_v that_o they_o be_v as_o sleep_n be_v a_o mean_n of_o recruit_v when_o all_o work_n and_o tug_v by_o defensive_a contraction_n fail_v and_o so_o the_o last_o refuge_n of_o the_o sensitive_a soul_n when_o overtired_n in_o order_n to_o recover_v strength_n for_o a_o fresh_a engagement_n with_o the_o enemy_n as_o be_v tire_v at_o night_n the_o sensitive_a soul_n loosen_v the_o rign_n of_o contraction_n to_o enable_v he_o the_o better_a to_o fall_v to_o his_o work_n the_o next_o day_n this_o you_o will_v find_v by_o all_o reason_n and_o experience_n to_o be_v the_o true_a state_n of_o leipothymy_n upon_o grievance_n and_o fatigue_n though_o not_o hitherto_o mind_v that_o i_o know_v of_o many_o true_a and_o useful_a consequence_n do_v hence_o follow_v as_o that_o we_o be_v not_o always_o to_o disturb_v they_o or_o put_v they_o out_o of_o these_o recruit_v leipothymy_n by_o grievous_a mean_n as_o pricking_n pinch_n etc._n etc._n but_o only_o by_o cordial_n and_o refresh_a thing_n as_o you_o will_v treat_v a_o person_n much_o tire_v or_o by_o let_v they_o take_v their_o nap_n if_o i_o may_v so_o call_v it_o if_o there_o be_v not_o very_o eminent_a danger_n but_o it_o be_v endless_a and_o beside_o my_o purpose_n to_o make_v a_o particular_a discourse_n of_o this_o matter_n which_o will_v belong_v more_o proper_o to_o my_o tract_n of_o animal_n mechanism_n 14._o death_n happen_v sometime_o though_o very_o rare_o and_o that_o in_o very_o weak_a people_n that_o take_v little_a or_o no_o sustenance_n because_o either_o when_o fall_v into_o such_o syncopes_fw-la they_o never_o come_v out_o of_o they_o by_o reason_n that_o they_o have_v not_o within_o they_o wherewith_o to_o recruit_v their_o spirit_n or_o that_o opium_n take_v they_o much_o spend_v and_o tire_v with_o distemper_n cause_n as_o in_o weak_a and_o weary_a people_n a_o most_o profound_a sopor_fw-la which_o not_o recruit_v they_o who_o take_v or_o digest_v no_o sustenance_n they_o must_v rather_o grow_v weak_a and_o weak_a for_o somewhat_o be_v spend_v while_o we_o live_v and_o consequent_o the_o sleep_n or_o sopor_fw-la more_o and_o more_o profound_a till_o they_o sleep_v their_o last_o for_o want_v of_o some_o recruit_v which_o be_v the_o very_a thing_n that_o natural_o lessen_v sleep_n and_o awake_v we_o when_o there_o be_v no_o other_o apparent_a cause_n for_o as_o the_o be_v tire_v and_o want_v of_o recruit_v cause_n sleep_v so_o the_o have_v it_o cause_v wake_v or_o which_o be_v the_o same_o in_o effect_n no_o far_o need_v of_o relaxation_n for_o recruit_n sake_n so_o that_o the_o sensitive_a soul_n fall_v to_o his_o useful_a work_n of_o vigilative_a contraction_n for_o sense_n and_o motion_n sake_n 15._o it_o sometime_o cause_n purge_v which_o happen_v as_o far_o as_o i_o have_v observe_v or_o can_v learn_v only_o when_o it_o be_v give_v in_o a_o good_a quantity_n to_o person_n of_o a_o strong_a digestion_n or_o canine_a appetite_n the_o case_n be_v thus_o when_o person_n that_o be_v of_o a_o strong_a digestion_n take_v a_o resinous_n opiate_n in_o good_a quantity_n they_o do_v in_o great_a measure_n by_o their_o fix_a salt_n at_o stomach_n and_o strong_a digestion_n subdue_v the_o volatility_n of_o the_o opium_n and_o dissolve_v its_o rosin_n which_o then_o as_o acrimonious_a rosin_n or_o vomit_n subdue_v by_o fix_a salt_n use_v to_o do_v cause_v purge_v hence_o it_o be_v that_o it_o general_o if_o not_o always_o purge_v dog_n and_o people_n of_o a_o high_a canine_a appetite_n and_o that_o sometime_o meet_v such_o fix_a salt_n it_o purge_v the_o consumptive_a bartholine_n say_v that_o mandrake_n juice_n purge_v when_o it_o meet_v with_o acrimonious_a fix_a salt_n erastus_n and_o quercelan_n do_v agree_v that_o it_o have_v a_o purgative_n quality_n but_o that_o it_o do_v not_o always_o exert_v it_o 1._o because_o it_o take_v away_o the_o sense_n of_o irritation_n 2._o because_o it_o be_v give_v in_o too_o small_a a_o quantity_n the_o reason_n be_v just_a and_o right_a and_o not_o only_o consistent_a with_o but_o confirm_v what_o i_o say_v note_v that_o this_o be_v not_o intend_v of_o the_o purge_v that_o happen_v after_o the_o declination_n of_o its_o operation_n which_o be_v as_o you_o will_v find_v from_o another_o cause_n therefore_o this_o do_v not_o smell_v of_o the_o opium_n as_o the_o other_o do_v because_o it_o be_v past_a and_o go_v before_o that_o in_o the_o declination_n happen_v of_o which_o more_o in_o its_o proper_a place_n 16._o it_o raise_v and_o revive_v some_o person_n that_o be_v almost_o expire_a in_o two_o case_n one_o be_v when_o such_o as_o have_v be_v use_v to_o take_v it_o be_v even_o expire_a for_o want_n of_o it_o of_o which_o more_o hereafter_o the_o other_o case_n be_v when_o violent_a contraction_n as_o from_o pain_n cold_a vomit_n and_o grievous_a passion_n as_o terror_n etc._n etc._n be_v the_o cause_n that_o people_n be_v almost_o expire_a for_o it_o take_v off_o the_o contraction_n by_o relax_v etc._n etc._n 17._o it_o stay_v very_o long_o at_o stomach_n when_o the_o rosin_n thereof_o stick_v to_o the_o stomach_n and_o be_v there_o detain_v beside_o that_o the_o stomach_n be_v relax_v and_o have_v little_a sense_n or_o motion_n as_o in_o sleep_n do_v not_o soon_o digest_v it_o or_o discharge_v it_o it_o be_v fine_a in_o this_o case_n and_o all_o other_o to_o observe_v how_o sensation_n and_o motion_n go_v hand_n in_o hand_n keep_v equal_a pace_n and_o equal_a proportion_n as_o it_o plain_o must_v be_v by_o the_o principle_n of_o relaxation_n and_o contraction_n which_o i_o have_v state_v and_o prove_v 18._o it_o cause_v stoppage_n of_o urine_n sometime_o especial_o in_o old_a people_n by_o over_o relax_v and_o cause_v a_o kind_n of_o a_o temporary_a palsy_n of_o the_o bladder_n as_o be_v show_v and_o take_v away_o the_o sense_n of_o the_o irritation_n of_o the_o urine_n which_o shall_v contract_v the_o bladder_n to_o squeeze_v it_o out_o by_o which_o mean_v it_o happen_v sometime_o that_o the_o bladder_n come_v to_o be_v so_o over_o extend_v beyond_o its_o due_a tone_n that_o they_o can_v contract_v it_o to_o make_v water_n in_o all_o which_o case_n strong_a contracter_n as_o cold_a terror_n etc._n etc._n immediate_o cure_v they_o the_o very_a put_v the_o scrotum_fw-la to_o the_o edge_n of_o a_o cold_a chamberpot_n have_v effect_v it_o several_a time_n by_o my_o advice_n though_o if_o need_v be_v you_o must_v come_v to_o dash_v of_o cold_a water_n upon_o the_o region_n of_o the_o bladder_n or_o pump_v on_o it_o or_o dip_v in_o it_o etc._n etc._n so_o terror_n and_o cause_v a_o very_a smart_n pain_n especial_o near_o those_o part_n will_v do_v much_o but_o cold_a be_v the_o ready_a and_o best_a remedy_n 19_o it_o sometime_o prove_v dangerous_a after_o great_a hemorrbage_n or_o evacuation_n as_o tapping_n in_o dropsy_n etc._n etc._n because_o the_o relaxation_n hinder_v the_o part_n due_o to_o contract_v upon_o what_o remain_v which_o may_v cause_v great_a mischief_n as_o discontinuation_n of_o motion_n etc._n etc._n thus_o have_v you_o all_o the_o constant_a frequent_a and_o rare_a effect_n of_o opium_n take_v internal_o in_o a_o moderate_a do_v so_o natural_o easy_o plain_o and_o mechanical_o explicate_v that_o people_n may_v in_o my_o judgement_n more_o admire_v how_o all_o fail_v of_o discover_v the_o manner_n of_o their_o production_n than_o that_o i_o find_v it_o as_o man_n be_v apt_a to_o think_v of_o the_o circulation_n of_o the_o blood_n which_o now_o as_o i_o hope_v the_o effect_n of_o opium_n do_v seem_v very_o obvious_a both_o which_o case_n be_v to_o i_o very_o strong_a argument_n of_o a_o be_v that_o rule_n and_o dispose_n darken_v and_o illuminate_v etc._n etc._n as_o he_o please_v when_o i_o consider_v that_o both_o the_o circulation_n of_o the_o blood_n and_o the_o cause_n of_o the_o operation_n of_o opium_n viz._n pleasure_n at_o stomach_n etc._n etc._n fall_v under_o the_o sense_n of_o many_o million_o who_o in_o one_o case_n see_v the_o blood_n move_v and_o in_o the_o other_o feel_v
the_o pleasure_n yet_o be_v neither_o discover_v for_o many_o thousand_o of_o year_n especial_o consider_v also_o that_o in_o the_o case_n of_o opium_n thousand_o of_o ingenious_a man_n have_v diligent_o inquire_v after_o the_o cause_n of_o its_o operation_n who_o make_v no_o far_a step_n in_o it_o then_o to_o state_n thing_n that_o have_v not_o as_o much_o as_o existence_n viz._n a_o cold_a quality_n and_o 〈◊〉_d fly_v from_o the_o stomach_n to_o the_o head_n to_o be_v the_o cause_n thereof_o therefore_o it_o be_v plain_a that_o neither_o be_v he_o that_o plant_n any_o thing_n neither_o he_o that_o water_v but_o god_n that_o give_v the_o increase_n of_o knowledge_n and_o of_o other_o thing_n to_o who_o be_v all_o glory_n chap._n xx._n the_o explication_n of_o the_o effect_n of_o the_o declination_n of_o the_o operation_n of_o opium_n in_o a_o moderate_a do_v 1._o a_o general_n return_v of_o all_o disease_n and_o disaster_n when_o the_o operation_n of_o opium_n be_v over_o because_o it_o do_v not_o as_o be_v show_v operate_v as_o a_o alterative_a but_o a_o please_a diverter_n of_o the_o sensitive_a soul_n for_o some_o time_n during_o which_o it_o cause_v a_o general_a relaxation_n of_o all_o the_o sensile_a part_n whereby_o the_o animal_n spirit_n be_v expanded_a grow_v unfit_a to_o convey_v impression_n smart_o which_o be_v requisite_a to_o cause_v a_o sense_n of_o pain_n etc._n etc._n as_o have_v be_v often_o say_v but_o it_o cure_v several_a distemper_n viz._n such_o as_o please_v and_o comfort_v the_o sensitive_a soul_n compose_v the_o spirit_n relaxation_n perspiration_n sweat_v etc._n etc._n can_v quite_o take_v away_o of_o which_o more_o particular_o when_o we_o come_v to_o speak_v of_o the_o use_n of_o opium_n in_o cure_n 2._o sweat_n happen_v in_o the_o declination_n of_o its_o operation_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v because_o that_o now_o all_o the_o parâ—s_a contract_n which_o by_o their_o relaxation_n suspend_v all_o humour_n during_o its_o operation_n do_v mechanical_o squeeze_v out_o the_o congest_a humour_n there_o be_v less_o room_n in_o the_o body_n as_o be_v say_v of_o sweat_n upon_o awake_v by_o the_o return_n of_o the_o vigilative_a contraction_n after_o relaxation_n during_o the_o sleep_n which_o be_v to_o be_v compare_v to_o the_o relaxation_n during_o the_o operation_n of_o opium_n and_o the_o return_v of_o the_o contraction_n when_o it_o be_v end_v beside_o that_o both_o upon_o the_o go_v off_o of_o the_o operation_n and_o awake_v the_o motion_n of_o the_o heart_n grow_v more_o vigorous_a as_o it_o do_v upon_o motion_n by_o the_o intentive_a contraction_n do_v more_o powerful_o propell_v the_o humour_n out_o at_o the_o pore_n as_o happen_v in_o sweat_n upon_o motion_n 3._o frequent_v make_v of_o water_n happen_v partly_o by_o the_o titillation_n of_o the_o volatile_a salt_n as_o by_o cantharides_n etc._n etc._n that_o be_v now_o separate_v from_o the_o blood_n partly_o by_o the_o contraction_n of_o the_o whole_a body_n squeese_v it_o out_o at_o the_o kidney_n as_o when_o people_n be_v cold_a they_o make_v more_o water_n for_o that_o reason_n 4._o a_o looseness_n may_v and_o do_v happen_v sometime_o from_o the_o like_a contraction_n squeese_v out_o the_o humour_n that_o be_v suspend_v during_o the_o relaxation_n by_o the_o opium_n which_o be_v common_a for_o such_o contraction_n to_o cause_n as_o by_o cold_a terror_n etc._n etc._n and_o because_o sensation_n grow_v more_o nice_a and_o irritable_a by_o the_o humour_n by_o reason_n of_o the_o contraction_n which_o be_v the_o more_o for_o the_o grievance_n of_o fail_v of_o the_o pleasure_n of_o opium_n therefore_o 5._o disease_n pain_n etc._n etc._n seem_v worse_o upon_o the_o return_n of_o the_o grievance_n because_o of_o the_o great_a ease_n they_o have_v during_o the_o operation_n of_o the_o opium_n contraria_fw-la inter_fw-la se_fw-la magis_fw-la elucescunt_fw-la and_o it_o be_v particular_o observe_v of_o pleasure_n that_o it_o leave_v man_n worse_o than_o it_o find_v they_o thus_o a_o man_n be_v worse_a more_o sad_a etc._n etc._n post_fw-la coitum_fw-la more_o melancholy_a after_o all_o sort_n of_o pleasure_n insomuch_o that_o it_o be_v grow_v to_o a_o proverb_n viz._n after_o merry_a come_v sorry_a or_o after_o mirth_n come_v sorrow_n as_o also_o minus_n gaudebis_fw-la minus_fw-la dolebis_fw-la therefore_o 6._o melaneholy_n do_v often_o if_o not_o always_o happen_v in_o some_o degree_n after_o its_o operation_n be_v end_v 1._o because_o of_o the_o return_n of_o the_o contraction_n or_o toil_n of_o the_o sensitive_a soul_n 2._o because_o as_o be_v say_v the_o sense_n of_o pleasure_n new_o lose_v aggravate_v the_o sorrow_n as_o have_v be_v show_v after_o coition_n etc._n etc._n 7._o the_o pulse_n be_v narrow_a because_o the_o contraction_n return_v with_o melancholy_a and_o return_v of_o disaster_n improve_v when_o that_o so_o happen_v as_o it_o general_o do_v 8._o itch_a of_o the_o skin_n happen_v about_o this_o time_n because_o that_o now_o the_o volatile_a salt_n which_o cause_v tuillation_n be_v arrive_v as_o far_o as_o the_o skin_n upon_o its_o march_n out_o of_o the_o body_n chap._n xxi_o the_o explication_n of_o the_o effect_n of_o opium_n in_o a_o excessive_a do_v the_o cause_n of_o most_o of_o these_o effect_n will_v be_v evident_a from_o the_o explication_n of_o the_o former_a because_o the_o difference_n be_v only_o in_o the_o quantity_n of_o the_o opium_n therefore_o i_o be_o often_o necessitate_v to_o speak_v much_o the_o same_o as_o i_o have_v do_v before_o you_o can_v expect_v any_o good_a effect_n from_o its_o excess_n any_o more_o than_o you_o have_v from_o wine_n though_o the_o best_a of_o cordial_n next_o to_o the_o sal._n volatile_a oleosum_fw-la of_o opium_n but_o rather_o less_o because_o opium_n be_v join_v to_o a_o pernicious_a rosin_n which_o you_o may_v be_v sure_o will_v be_v very_o grievous_a to_o the_o stomach_n in_o great_a quantity_n if_o it_o be_v so_o in_o little_a the_o evil_a effect_n in_o this_o case_n do_v main_o proceed_v either_o from_o too_o much_o relaxation_n as_o in_o drunkenness_n or_o from_o the_o rosin_n at_o stomach_n 1._o a_o heat_n at_o stomach_n be_v cause_v by_o the_o intense_a heat_n of_o the_o opium_n in_o a_o great_a quantity_n it_o be_v sensible_o a_o very_a hot_a thing_n 2._o the_o sense_n of_o weight_n at_o stomach_n be_v cause_v by_o the_o great_a relaxation_n that_o it_o cause_n which_o render_v the_o stomach_n proportionable_o weak_a and_o unable_a to_o endeavour_v its_o own_o relief_n so_o that_o the_o rosin_n etc._n etc._n lie_v heavy_a upon_o it_o thus_o we_o find_v a_o great_a heaviness_n at_o stomach_n when_o any_o thing_n grieve_v it_o that_o it_o can_v reject_v or_o discharge_v 3._o gaity_n of_o humour_n be_v cause_v at_o first_o as_o by_o the_o pleasure_n of_o a_o great_a quantity_n of_o wine_n by_o its_o please_a agreeableness_n to_o the_o membrane_n at_o stomach_n till_o the_o relaxation_n grow_v enormous_a as_o by_o a_o great_a do_v of_o wine_n sudden_o drink_v to_o which_o it_o be_v very_o like_a in_o all_o its_o effect_n except_o such_o as_o proceed_v from_o the_o rosin_n stick_v at_o stomach_n which_o wine_n have_v not_o 4._o sardonick_a laughter_n be_v cause_v as_o you_o see_v in_o drunken_a people_n when_o they_o be_v disable_v by_o the_o great_a relaxation_n that_o they_o can_v well_o express_v themselves_o by_o the_o fail_a tongue_n they_o endeavour_v it_o by_o a_o silly_a kind_n of_o feign_a or_o make_v laughter_n as_o they_o call_v it_o while_o the_o please_a titillation_n at_o stomach_n much_o incline_v they_o to_o mirth_n if_o they_o know_v how_o to_o manage_v and_o carry_v it_o on_o 5._o laxity_n and_o consequent_o debility_n of_o all_o part_n be_v cause_v by_o the_o extraordinary_a relaxation_n of_o they_o by_o a_o continual_a and_o permanent_a sense_n of_o pleasure_n which_o happen_v considerable_o in_o the_o momentary_a pleasure_n of_o venus_n much_o more_o in_o this_o continual_a and_o last_a pleasure_n when_o a_o great_a do_v make_v it_o intense_a as_o in_o drunkenness_n 6._o alienation_n of_o the_o mind_n be_v cause_v as_o in_o drunkenness_n by_o a_o over_o relaxation_n of_o the_o brain_n and_o its_o membrane_n 7._o loss_n of_o memory_n happen_v by_o the_o same_o mean_n as_o in_o drunkenness_n so_o 8._o darkness_n of_o eye_n be_v cause_v by_o a_o relaxation_n of_o the_o coat_n and_o membrane_n of_o the_o eye_n but_o main_o by_o the_o expansion_n of_o the_o animal_n spirit_n by_o that_o relaxation_n which_o as_o in_o sleep_n render_v they_o unfit_a to_o convey_v the_o impression_n of_o light_n etc._n etc._n 9_o laxity_n of_o the_o cornea_n be_v from_o the_o same_o relaxation_n 10._o appearance_n of_o various_a colour_n happen_v by_o as_o be_v say_v the_o unevenness_n of_o the_o cornea_n etc._n etc._n when_o so_o relax_v whereas_o when_o it_o be_v due_o
and_o frequent_a erection_n be_v and_o must_v be_v from_o the_o same_o cause_n 17._o nocturnal_a pollution_n be_v necessary_a consequence_n of_o the_o relaxation_n and_o the_o titillation_n cause_v by_o those_o volatile_a salt_n as_o be_v say_v chap._n xxiii_o the_o explication_n of_o the_o effect_n of_o leave_v off_o opium_n after_o a_o long_a and_o lavish_a use_v thereof_o i._o great_a and_o even_o intolerable_a distress_n anxiety_n and_o depression_n of_o spirit_n do_v happen_v 1._o because_o the_o sensitive_a soul_n who_o be_v so_o much_o comfort_v divert_v and_o support_v by_o the_o habitual_a and_o dear_o belove_a pleasure_n that_o opium_n cause_n be_v sudden_o deprive_v thereof_o by_o which_o it_o be_v main_o sustain_v be_v exceed_o disappoint_v and_o cast_v down_o 2._o because_o he_o now_o labour_v under_o the_o sore_a burden_n of_o the_o three_o contraction_n so_o that_o every_o thing_n seem_v and_o be_v real_o more_o grievous_a â—o_o he_o for_o now_o it_o act_v as_o one_o in_o pain_n or_o grief_n and_o every_o thing_n affect_v he_o more_o smart_o proportionable_a to_o the_o compression_n cause_v thereby_o of_o the_o animal_n spirit_n unless_o he_o return_v to_o the_o pleasure_n of_o opium_n which_o elevate_v it_o again_o or_o use_v generous_a wine_n as_o its_o substitute_n though_o it_o do_v not_o equal_v it_o either_o in_o the_o intenseness_n or_o duration_n of_o the_o pleasure_n unless_o repeat_v as_o i_o have_v some_o where_o direct_v once_o in_o half_a a_o hour_n or_o a_o hour_n in_o a_o moderate_a manner_n which_o cause_v a_o continuance_n of_o the_o pleasure_n though_o it_o can_v equal_v the_o intenseness_n of_o that_o of_o opium_n which_o therefore_o have_v the_o great_a effect_n ii_o a_o return_n of_o all_o disease_n pain_n and_o disaster_n must_v happen_v general_o because_o the_o opium_n take_v they_o off_o by_o a_o bare_a diversion_n of_o the_o sense_n thereof_o by_o pleasure_n iii_o dangerous_a looseness_n happen_v sometime_o because_o the_o sensation_n grow_v more_o grievous_a for_o as_o the_o pleasant_a sensation_n cause_v by_o opium_n take_v away_o the_o perception_n of_o the_o irritation_n of_o humour_n so_o the_o grievance_n of_o lose_v that_o pleasure_n cause_v contraction_n make_v all_o sensation_n smart_a and_o consequent_o more_o irritate_v so_o that_o the_o humour_n have_v thereby_o more_o of_o the_o effect_n of_o purger_n which_o operate_v as_o all_o agree_v by_o irritation_n beside_o that_o the_o humour_n before_o detain_v and_o suspend_v by_o relaxation_n as_o in_o sleep_n be_v now_o therefore_o pour_v down_o in_o great_a quantity_n by_o the_o advance_a contraction_n squeese_v they_o out_o as_o the_o return_n of_o the_o vigilative_a contraction_n after_o sleep_n cause_n man_n to_o be_v more_o apt_a to_o go_v to_o stool_n upon_o awake_v or_o get_v up_o in_o the_o morning_n which_o may_v be_v well_o compare_v in_o some_o measure_n to_o purge_v after_o leave_v off_o the_o use_n of_o opium_n since_o it_o relax_n as_o sleep_n do_v and_o that_o for_o a_o much_o long_a time_n by_o a_o continue_a use_n thereof_o iv_o death_n common_o follow_v for_o all_o the_o reason_n aforesaid_a especial_o the_o great_a and_o intolerable_a distress_n of_o soul_n that_o they_o be_v under_o unless_o opium_n be_v use_v which_o soon_o set_v they_o right_o or_o wine_n its_o substitute_n so_o frequent_o use_v as_o to_o continue_v its_o cordial_a pleasure_n at_o stomach_n nothing_o now_o remain_v but_o to_o take_v a_o short_a review_n to_o see_v whether_o i_o have_v explain_v all_o the_o amaze_a contradiction_n that_o seem_v to_o be_v in_o the_o effect_n of_o opium_n for_o though_o it_o be_v real_o do_v yet_o may_v it_o not_o so_o well_o appear_v as_o when_o set_v one_o against_o the_o other_o it_o will_v be_v tautology_n to_o repeat_v all_o the_o reason_n therefore_o i_o shall_v only_o mention_v they_o in_o the_o close_a order_n i_o at_o first_o enumerate_v they_o that_o you_o may_v see_v that_o they_o be_v all_o explicate_v in_o the_o former_a discourse_n you_o may_v well_o remember_v that_o i_o have_v show_v 1._o how_o it_o cause_v sleep_v and_o watch_v in_o divers_a person_n 2._o how_o it_o cause_v and_o prevent_v sweat_n 3._o how_o it_o relax_n and_o stop_n looseness_n even_o by_o relax_v 4._o how_o it_o stop_v flux_n and_o promote_v sweat_v and_o perspiration_n 5._o how_o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v it_o 6._o how_o it_o cause_v stupidity_n if_o you_o sit_v or_o lie_v still_o otherwise_o promptitude_n in_o business_n 7._o how_o it_o cause_v cloudiness_n and_o serenity_n that_o if_o one_o lie_v still_o and_o doze_n this_o if_o he_o keep_v in_o action_n that_o by_o a_o excessive_a and_o lavish_a use_v thereof_o which_o cause_v moapishness_n this_o by_o a_o temperate_a occasional_a take_v thereof_o especial_o in_o the_o morning_n upon_o journey_n etc._n etc._n 8._o how_o it_o excite_v the_o spirit_n yet_o quiet_v and_o compose_v they_o in_o hysterick_n fit_v diary_n fever_n from_o pain_n commotion_n etc._n etc._n 9_o how_o that_o it_o be_v very_o hot_a and_o take_v of_o fever_n 10._o how_o though_o it_o be_v hot_a and_o bitter_a yet_o it_o lessen_v appetite_n and_o hunger_n which_o be_v a_o grievous_a sensation_n by_o cause_v a_o pleasant_a one_o 11._o how_o it_o sometime_o stop_v urine_n by_o relax_v the_o bladder_n suspending_a humour_n etc._n etc._n and_o promote_v it_o by_o its_o tickle_a volatile_a salt_n as_o cantharides_n bee_n aunt_n etc._n etc._n do_v 12._o how_o it_o relax_n and_o thereby_o weaken_v as_o in_o sleep_n etc._n etc._n yet_o enable_v to_o perform_v labour_n journey_n etc._n etc._n with_o great_a euphory_n by_o divertive_a pleasure_n 13._o how_o it_o cause_v and_o prevent_v abortion_n that_o by_o over-relaxing_a this_o by_o allay_a pain_n terror_n etc._n etc._n that_o may_v cause_v it_o 14._o how_o it_o stop_v vomit_v by_o take_v off_o irritation_n etc._n etc._n and_o cause_v it_o by_o the_o adherence_n of_o its_o indigestible_a and_o viscid_a rosin_n 15._o how_o it_o stop_v purge_v and_o sometime_o cause_v it_o by_o the_o dissolution_n of_o its_o rosin_n by_o a_o strong_a digestion_n fix_a salt_n etc._n etc._n when_o its_o quantity_n be_v considerable_a which_o make_v it_o happen_v but_o rare_o 16._o how_o though_o acrimonious_a it_o take_v away_o the_o sense_n of_o acrimony_n 17._o how_o it_o cause_v madness_n and_o cure_v it_o by_o compose_v the_o spirit_n etc._n etc._n 18._o how_o it_o cause_v palsy_n by_o relax_v the_o part_n and_o make_v they_o susceptible_a of_o humour_n cause_v ill_a digestion_n etc._n etc._n and_o may_v cure_v they_o as_o dr._n willis_n give_v a_o instance_n by_o open_v the_o pore_n 19_o how_o it_o cause_v palsy_n and_o cure_n stupor_n etc._n etc._n that_o proceed_v from_o cold_a and_o contract_n cause_n 20._o how_o it_o cause_v dryness_n in_o the_o mouth_n yet_o by_o take_v off_o fever_n often_o cure_v it_o 21._o how_o it_o take_v off_o hiccough_n and_o cause_v they_o as_o it_o do_v vomit_v and_o for_o the_o same_o cause_n 22._o how_o it_o stanch_v blood_n by_o quiet_v its_o motion_n yet_o promote_v the_o menses_fw-la and_o lochia_n by_o relax_v open_v and_o widen_v the_o vessel_n and_o pore_n 23._o how_o it_o stop_v critical_a motion_n that_o depend_v upon_o irritation_n and_o contraction_n and_o promote_v such_o as_o depend_v upon_o open_v the_o pore_n 24._o how_o it_o revive_v people_n that_o be_v at_o the_o point_n of_o death_n for_o want_n of_o opium_n or_o by_o violent_a contraction_n and_o convulsion_n and_o be_v fatal_a to_o other_o weak_a person_n 25._o how_o it_o cause_v convulsion_n by_o its_o grieve_v rosin_n and_o cure_v they_o by_o quiet_v and_o compose_v the_o spirit_n by_o please_v they_o 26._o how_o it_o cause_v contraction_n by_o the_o grievous_a sensation_n that_o its_o rosin_n cause_n and_o relaxation_n by_o the_o pleasant_a sensation_n that_o its_o salvolatile_a oleosum_fw-la cause_n by_o that_o it_o cause_v many_o ill_a effect_n not_o here_o name_v and_o by_o this_o it_o cure_v they_o for_o how_o can_v such_o contrary_a cause_n according_a as_o one_o or_o the_o other_o prevail_v not_o cause_v contrary_a and_o seem_o contradictory_n effect_n at_o divers_a time_n and_o in_o divers_a person_n 27._o how_o it_o relax_n yet_o cause_v the_o tension_n rigidity_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n by_o its_o titillation_n thus_o have_v you_o all_o even_o the_o most_o mysterious_a and_o seem_o contradictory_n effect_n of_o opium_n explain_v and_o reconcile_v and_o that_o so_o easy_o that_o if_o there_o be_v no_o other_o proof_n of_o the_o truth_n of_o my_o foundation_n it_o be_v sufficient_a to_o convince_v any_o man_n of_o its_o validity_n consider_v the_o vastness_n of_o the_o number_n and_o perplexity_n of_o the_o nature_n of_o those_o effect_n that_o be_v all_o with_o such_o facility_n explain_v be_v able_a even_o
to_o disparage_v the_o performance_n as_o mean_v and_o obvious_a like_o that_o of_o the_o circulation_n of_o the_o blood_n or_o america_n when_o find_v out_o do_v not_o the_o newness_n of_o the_o thing_n the_o baffle_a endeavour_n of_o all_o mankind_n and_o the_o seem_a impossibility_n of_o ever_o find_v it_o out_o which_o be_v almost_o agree_v upon_o speak_v in_o its_o behalf_n consider_v that_o nothing_o can_v be_v plain_a and_o easy_a but_o what_o be_v true_a and_o consequent_o nothing_o valuable_a but_o what_o be_v so_o what_o be_v true_a knowledge_n but_o the_o knowledge_n of_o thing_n as_o they_o real_o be_v and_o when_o a_o thing_n be_v know_v as_o real_o as_o it_o be_v it_o must_v be_v plain_a and_o never_o so_o till_o then_o for_o to_o take_v a_o thing_n to_o be_v what_o it_o be_v not_o be_v all_o darkness_n error_n puzzle_n confusion_n and_o vanity_n as_o all_o discourse_n of_o opium_n have_v hitherto_o be_v it_o be_v no_o wonder_n then_o that_o the_o cause_n of_o the_o operation_n of_o opium_n grow_v more_o and_o more_o obscure_a while_o they_o state_v the_o cold_a quality_n of_o very_a hot_a opium_n the_o belch_a up_o of_o vulcano_n of_o fume_n from_o the_o stomach_n to_o the_o head_n which_o have_v no_o existence_n their_o act_n as_o a_o poison_n of_o the_o animal_n spirit_n their_o fix_v and_o coagulate_v they_o their_o clog_a they_o by_o adherence_n or_o cloud_v they_o their_o wedge_a themselves_o among_o the_o animal_n spirit_n none_o know_v how_o and_o thereby_o disable_n they_o their_o stuff_v the_o pore_n of_o the_o brain_n or_o compress_v it_o and_o thereby_o hinder_v the_o generation_n of_o animal_n spirit_n to_o be_v the_o cause_n of_o the_o noble_a and_o pleasant_a operation_n of_o opium_n without_o any_o foundation_n in_o nature_n or_o the_o least_o evidence_n of_o sense_n or_o reason_n but_o vain_a fantastical_a imagination_n form_v in_o the_o chimera-forges_a of_o their_o wanton_a brain_n while_o they_o endeavour_v right_o or_o wrong_n to_o appear_v considerable_a folk_n by_o do_v nothing_o to_o the_o purpose_n in_o a_o kind_n of_o pretty_a plausible_a and_o impose_v manner_n thereby_o stuff_v the_o unwary_a world_n with_o wrong_n and_o vain_a conception_n and_o impertinent_a prejudices_fw-la which_o be_v the_o great_a obstacle_n of_o knowledge_n i_o will_v fain_o know_v which_o of_o those_o hypothesise_n can_v tolerable_o solve_v 1_o in_o 10_o of_o the_o phenomena_n that_o i_o have_v enumerate_v or_o indeed_o any_o one_o phenomenon_n true_o mechanical_o and_o demonstrative_o yet_o be_v those_o whim_n the_o glorious_a production_n of_o thousand_o of_o year_n study_n and_o solicitous_a disquisition_n though_o every_o one_o that_o take_v opium_n actual_o feel_v the_o true_a cause_n of_o its_o operation_n viz._n the_o please_a delight_n that_o it_o occasion_v by_o affect_v the_o membrane_n and_o animal_n spirit_n after_o the_o manner_n that_o i_o have_v at_o large_a set_v forth_o good_a god_n what_o blund'r_a groper_n be_v mankind_n who_o daily_o feel_v the_o cause_n it_o never_o can_v find_v though_o thousand_o seek_v it_o with_o a_o eager_a mind_n chap._n xxiv_o of_o opium_n separate_v from_o its_o noxious_a part_n or_o rosin_n and_o whether_o it_o be_v a_o panacea_fw-la etc._n etc._n thus_o far_o have_v i_o speak_v of_o crude_a opium_n joint_o with_o its_o rosin_n or_o noxious_a part_n now_o i_o will_v consider_v it_o separate_v from_o it_o and_o show_v how_o to_o do_v it_o galen_n say_v that_o it_o be_v very_o difficult_a to_o find_v a_o excellent_a remedy_n without_o a_o noxious_a quality_n and_o it_o be_v as_o difficult_a to_o find_v any_o thing_n so_o noxious_a as_o not_o to_o afford_v a_o good_a medicament_n which_o you_o see_v in_o viper_n scorpion_n mercury_n etc._n etc._n all_o or_o most_o physician_n unanimous_o agree_v that_o opium_n have_v such_o a_o noxious_a quality_n that_o cause_v vomit_n hiccough_n distress_n anxiety_n convulsion_n chief_o at_o or_o about_o the_o region_n of_o the_o stomach_n and_o that_o if_o it_o be_v free_v from_o it_o it_o will_v be_v the_o noble_a of_o medicament_n who_o can_v otherwise_o imagine_v see_v it_o be_v so_o excellent_a and_o universal_a a_o remedy_n as_o it_o be_v now_o use_v in_o the_o world_n without_o such_o a_o excellent_a preparation_n thereof_o wherein_o the_o noxious_a principle_n be_v separate_v from_o it_o of_o which_o paracelsus_n say_v that_o whoever_o shall_v enjoy_v it_o will_v be_v a_o professor_n of_o no_o less_o knowledge_n than_o apollo_n machaon_n or_o podalyrius_n though_o he_o be_v the_o great_a master_n of_o arcanas_fw-la panaceas_fw-la etc._n etc._n yet_o do_v he_o confess_v that_o a_o preparation_n of_o opium_n stand_v he_o in_o stead_n and_o perform_v his_o business_n when_o all_o his_o great_a medicament_n fail_v he_o and_o that_o it_o will_v dissolve_v disease_n as_o fire_n doeâ—_n snow_n or_o use_v word_n to_o the_o same_o effect_n helmont_n be_v in_o a_o kind_n of_o rapture_n upon_o consideration_n of_o its_o excellency_n burst_v out_o into_o this_o exclamation_n happy_a be_v the_o sick_a man_n who_o physician_n know_v how_o to_o separate_v the_o deadly_a or_o noxious_a part_v from_o opium_n platerus_n affirm_v that_o he_o can_v with_o a_o preparation_n of_o opium_n preserve_v the_o break_a wheel_n of_o life_n etmuller_n say_v that_o opium_n may_v 〈◊〉_d be_v esteem_v a_o general_a remedy_n and_o the_o main_a end_n of_o his_o tract_n de_fw-fr paruis_fw-la morborum_fw-la initiis_fw-la be_v to_o show_v how_o volatiles_fw-la more_o especial_o salia-volatilia-oleosa_a as_o that_o of_o opium_n may_v in_o small_a quantity_n alter_v we_o and_o cure_v our_o disease_n it_o be_v endless_a to_o tell_v you_o the_o eulogy_n of_o the_o learned_a concern_v such_o a_o preparation_n of_o opium_n which_o they_o general_a conclude_v to_o be_v a_o most_o noble_a panacea_fw-la therefore_o many_o and_o very_o solicitous_a have_v be_v the_o disquisition_n of_o the_o ingenious_a and_o industrious_a to_o find_v out_o this_o heroic_a generous_a and_o most_o glorious_a medicament_n i_o be_o full_o satisfy_v that_o the_o pure_a sal-volatile-oleosum_a of_o opium_n due_o separate_v from_o its_o noxious_a rosin_n dross_n etc._n etc._n be_v the_o very_a thing_n some_o of_o the_o reason_n that_o convince_v i_o be_v as_o follow_v viz._n 1._o because_o opium_n have_v no_o other_o principle_n in_o it_o that_o signify_v any_o thing_n as_o to_o its_o laudable_a and_o noble_a effect_n but_o its_o sal_fw-la volatile_a oleosum_fw-la as_o have_v be_v show_v 2._o because_o the_o sal_fw-la volatile-oleosum_a of_o opium_n produce_v all_o its_o good_a effect_n 3._o because_o the_o sal-volatile-oleosum_a due_o separate_v from_o its_o rosin_n and_o other_o principle_n produce_v no_o ill_a effect_n in_o a_o moderate_a do_v this_o add_v to_o what_o have_v be_v discourse_v at_o large_a of_o the_o principle_n of_o opium_n be_v i_o think_v sufficient_a to_o satisfy_v any_o man_n that_o the_o sal-volatile-oleosum_a of_o opium_n so_o separate_v be_v the_o great_a panacea_fw-la that_o be_v seek_v for_o however_o because_o we_o be_v upon_o the_o great_a thing_n in_o physic_n as_o may_v be_v well_o infer_v from_o what_o have_v be_v already_o say_v and_o that_o the_o world_n have_v be_v under_o great_a fear_n jealousy_n and_o blindness_n concern_v this_o matter_n and_o the_o use_v of_o opium_n it_o will_v be_v well_o worth_a our_o while_n to_o give_v all_o imaginable_a satisfaction_n in_o this_o case_n therefore_o i_o will_v first_o lay_v down_o all_o the_o requisite_a qualification_n of_o a_o complete_a panacea_fw-la as_o far_o as_o i_o can_v collect_v out_o of_o the_o most_o eminent_a author_n and_o my_o own_o consideration_n thereof_o second_o i_o will_v particular_o inquire_v as_o to_o each_o of_o the_o qualification_n whether_o the_o sal_fw-la volatile-oleosum_a of_o opium_n due_o separate_v from_o every_o other_o principle_n of_o opium_n be_v furnish_v therewith_o three_o i_o will_v show_v you_o how_o due_o to_o separate_v its_o dross_n rosin_n etc._n etc._n so_o as_o to_o leave_v a_o pure_a sincere_a sal-volatile-oleosum_a of_o opium_n for_o use._n the_o requisite_a qualification_n of_o a_o panacea_fw-la be_v these_o viz._n 1._o that_o it_o shall_v high_o please_v our_o sensation_n at_o stomach_n because_o the_o stomach_n be_v contrive_v and_o appoint_v by_o god_n and_o nature_n as_o the_o touchstone_n to_o try_v a_o sentinel_n true_o to_o inform_v and_o a_o critical_a judge_n to_o determine_v what_o be_v or_o be_v not_o agreeable_a to_o our_o nature_n in_o general_a and_o therefore_o as_o have_v be_v show_v endue_v with_o a_o wonderful_a sagacity_n and_o nicety_n of_o sensation_n for_o that_o end_n it_o follow_v then_o that_o a_o panacea_fw-la shall_v be_v very_o please_v and_o agreeable_a to_o the_o stomach_n and_o therefore_o very_o cordial_a 2._o that_o it_o shall_v be_v high_o please_v to_o the_o sensitive_a soul_n which_o be_v the_o principle_n of_o all_o motion_n action_n
principle_n of_o motion_n by_o which_o all_o ill_a matter_n be_v effective_o subdue_v when_o they_o act_v with_o alacrity_n and_o vigour_n they_o be_v the_o principal_a agent_n and_o we_o physician_n but_o as_o be_v say_v minister_n or_o as_o handmaid_n to_o offer_v or_o hand_n good_a matter_n medicament_n or_o instrument_n to_o those_o principal_a agent_n of_o nature_n and_o that_o this_o sal-volatile-oleosum_a of_o opium_n be_v the_o most_o proper_a matter_n or_o medicament_n we_o can_v put_v into_o nature_n hand_n so_o invigorate_v appear_v manifest_o in_o that_o 5._o its_o principle_n be_v the_o most_o agreeable_a to_o the_o best_a noble_a most_o active_a and_o predominant_a principle_n of_o our_o body_n as_o have_v be_v prove_v most_o evident_o plene_fw-la &_o plane_n nor_o be_v it_o only_o agreeable_a but_o 6._o more_o vigorous_a and_o powerful_a to_o actuate_v reduce_v alter_v or_o exalt_v our_o principle_n according_a to_o the_o direction_n of_o our_o invigorated_a nature_n or_o sensitive_a soul_n and_o spirit_n which_o have_v so_o convenient_a a_o instrument_n and_o high_o qualify_v a_o matter_n will_v soon_o alter_v the_o perverse_a renew_v the_o decay_a acuate_v the_o dull_a and_o elevate_v the_o depress_v effete_a and_o pall_a humour_n of_o our_o body_n especial_o see_v 7._o that_o the_o sal-volatile-oleosum_a of_o opium_n be_v so_o agreeable_a and_o powerful_a must_v be_v the_o great_a resolver_n of_o humour_n that_o can_v be_v imagine_v for_o all_o resolution_n be_v by_o a_o agreement_n of_o particle_n which_o make_v they_o easy_o miscible_a insinuate_v into_o and_o penetrate_v each_o other_o especial_o if_o one_o be_v somewhat_o more_o vigorous_a and_o penetrate_a than_o the_o other_o as_o the_o sal-volatile-oleosum_a have_v be_v plain_o prove_v to_o be_v thus_o it_o be_v that_o all_o menstruum_n do_v so_o resolve_v thing_n of_o their_o own_o nature_n and_o so_o purify_v and_o cleanse_v they_o by_o take_v to_o themselves_o what_o be_v mere_o and_o pure_o of_o the_o same_o nature_n and_o reject_v or_o let_v go_v their_o hold_n of_o what_o be_v otherwise_o where_o it_o be_v worth_a note_n how_o upon_o the_o account_n of_o the_o intimate_a combination_n and_o union_n of_o the_o volatile_a salt_n and_o oily_a part_n in_o our_o panacea_fw-la it_o be_v dissolvable_a in_o all_o menstruum_n and_o consequent_o a_o universal_a resolvent_fw-la of_o all_o the_o humour_n of_o our_o body_n which_o its_o external_a resolve_v of_o all_o humour_n and_o tumor_n do_v also_o prove_v now_o if_o it_o be_v such_o a_o resolver_n of_o which_o there_o be_v no_o place_n to_o doubt_v then_o as_o claudius_n de_fw-fr la_fw-fr courvee_n say_v it_o must_v excel_v all_o thing_n in_o alter_v and_o reduce_v all_o the_o humour_n of_o our_o body_n to_o a_o good_a and_o agreeable_a condition_n nor_o do_v it_o only_o thus_o resolve_v they_o and_o thereby_o separate_v as_o be_v say_v the_o good_a from_o the_o bad_a but_z 8._o when_o it_o have_v so_o do_v it_o by_o the_o amicable_a agreeableness_n of_o its_o sal-volatile-oleosum_a compose_v faculty_n strict_a combination_n of_o its_o principle_n join_v to_o concentrate_n congregate_n and_o as_o it_o be_v cement_v the_o best_a and_o most_o agreeable_a into_o a_o close_a union_n and_o firm_a texture_n by_o as_o be_v say_v the_o direction_n of_o invigorated_a nature_n which_o be_v of_o itself_o the_o good_a be_v once_o separate_v from_o the_o bad_a high_o sufficient_a without_o any_o other_o help_v to_o unite_v part_n so_o agreeable_a and_o of_o themselves_o incline_v to_o unite_v and_o combine_v though_o all_o tho_o part_n of_o opium_n like_o those_o of_o the_o great_a dissolvent_a be_v go_v and_o when_o that_o be_v do_v 9_o the_o high_a discussive_a quality_n of_o the_o sal-volatile-oleosum_a must_v be_v very_o effectual_a for_o the_o difflation_n and_o discussion_n of_o the_o sever_a effete_a particle_n which_o must_v be_v high_o assist_v and_o improve_v by_o the_o brisk_a and_o cheerful_a motion_n of_o nature_n viz._n the_o sensitive_a soul_n and_o spirit_n so_o as_o be_v aforesaid_a invigorate_v nor_o be_v this_o all_o but_o to_o complete_a and_o perfect_a the_o operation_n 10._o it_o lay_v open_a all_o the_o pore_n of_o the_o body_n as_o have_v be_v demonstrate_v 〈◊〉_d they_o out_o and_o give_v the_o ill_a particle_n their_o â—inal_n exit_fw-la by_o the_o most_o natural_a and_o plentiful_a way_n of_o evacuation_n leave_v the_o body_n free_a from_o all_o miasm_n and_o impurity_n 11._o i_o have_v sufficient_o show_v how_o unalterable_a it_o be_v in_o itself_o chap._n 15._o so_o that_o like_o the_o liquor_n alcahest_fw-mi it_o be_v not_o make_v to_o be_v subdue_v but_o to_o subdue_v and_o resolve_v humour_n now_o what_o can_v be_v require_v more_o in_o a_o medicament_n and_o how_o can_v the_o sensitive_a soul_n and_o spirit_n or_o nature_n so_o invigorate_v and_o endue_v with_o all_o euphory_n and_o cheerfulness_n by_o this_o glorious_a medicament_n who_o principle_n be_v not_o only_o agreeable_a to_o our_o noble_a one_o but_o more_o powerful_a and_o intimate_o combine_v so_o resolve_v of_o humour_n ready_a to_o unite_v the_o good_a and_o to_o discuss_v the_o bad_a and_o carry_v they_o off_o by_o the_o pore_n ever_o fail_v be_v due_o administer_v of_o good_a effect_n in_o alter_v all_o the_o humour_n of_o our_o body_n hypocrates_n in_o his_o book_n de_fw-fr nature_n hominis_fw-la state_n the_o cause_n of_o disease_n to_o be_v a_o disgregation_n of_o humour_n by_o which_o he_o seem_v to_o imply_v that_o the_o power_n of_o congregate_a and_o concentrate_v of_o humour_n be_v sufficient_a to_o accomplish_v a_o panacea_fw-la which_o be_v but_o one_o single_a qualification_n in_o eleven_o of_o our_o sal-volatile-oleosum_a though_o this_o alone_a as_o be_v experience_v even_o in_o common_a preparation_n of_o opium_n suffice_v very_o often_o to_o cure_v disease_n by_o compose_v commotion_n as_o in_o diary_n fever_n from_o perturbation_n etc._n etc._n thus_o the_o bitter_a and_o firm_a texture_v cortex_fw-la as_o i_o have_v show_v in_o my_o book_n de_fw-fr febribus_fw-la intermittentibus_fw-la take_v off_o ague_n fit_v by_o re-combining_a the_o segregated_a humour_n with_o the_o blood_n which_o it_o sudden_o do_v leave_v a_o disposition_n in_o the_o blood_n when_o ever_o it_o meet_v with_o a_o segregate_a cause_n as_o purge_v violent_a motion_n insolation_n intemperate_a drink_v etc._n etc._n to_o a_o relapse_n by_o a_o second_o separation_n of_o the_o morbid_v matter_n from_o it_o as_o you_o have_v it_o more_o at_o large_a in_o my_o say_a book_n p._n 166_o 167_o etc._n etc._n 242_o 243_o etc._n etc._n where_o you_o may_v see_v how_o opiate_n conduce_v very_o much_o to_o a_o speedy_a cure_n by_o the_o cortex_fw-la by_o compose_v etc._n etc._n martianus_n say_v coâ—m_fw-la de_fw-fr locis_fw-la in_o homine_fw-la p._n 76._o opium_n sist_z it_o &_o prohibet_fw-la humorum_fw-la disgregationem_fw-la that_o be_v opium_n hinder_v disgregation_n of_o humour_n now_o you_o may_v perceive_v the_o true_a qualification_n of_o a_o sal-volatile-oleosum_a so_o much_o seek_v for_o by_o the_o learned_a as_o a_o panacea_fw-la and_o how_o far_o the_o common_a one_o that_o be_v sell_v in_o the_o apothecary_n shop_n be_v from_o be_v such_o silvius_n indeed_o have_v a_o excellent_a one_o with_o which_o he_o do_v many_o and_o great_a cure_n which_o be_v consider_v have_v he_o not_o confess_v his_o ignorance_n of_o the_o cause_n of_o the_o effect_n of_o opium_n and_o the_o narrative_a he_o make_v of_o its_o virtue_n and_o performance_n in_o his_o preface_n to_o the_o first_o book_n of_o his_o praxis_fw-la and_o that_o he_o delight_v so_o much_o in_o the_o use_n of_o opium_n even_o when_o he_o be_v young_a that_o he_o be_v call_v by_o the_o name_n of_o doctor_n opiatus_fw-la and_o that_o he_o declare_v no_o oil_n be_v add_v in_o its_o preparation_n and_o that_o it_o be_v intimate_v that_o the_o oil_n and_o volatile_a part_n be_v strict_o combine_v will_v have_v make_v i_o suspect_n that_o it_o be_v the_o sal-volatile-oleosum_a of_o opium_n that_o he_o use_v which_o if_o it_o be_v not_o i_o dare_v be_v confident_a that_o notwithstanding_o all_o its_o excellency_n it_o be_v not_o as_o good_a i_o be_o very_a well_o satisfy_v that_o a_o true_a and_o consummate_v sal-volatile-oleosum_a be_v not_o to_o be_v make_v bare_o by_o art_n enquirer_n may_v have_v better_a success_n if_o they_o seek_v it_o among_o the_o natural_a tribe_n of_o bitter_a plant_n that_o be_v agreeable_a to_o the_o stomach_n which_o have_v all_o in_o they_o a_o sal-volatile-oleosum_a but_o how_o to_o pick_v and_o cull_v be_v i_o think_v best_o see_v by_o the_o requisite_a qualification_n of_o a_o panacea_fw-la that_o i_o have_v state_v there_o have_v be_v many_o in_o who_o hand_n bitter_a thing_n have_v be_v as_o a_o panacea_fw-la one_o in_o germany_n cure_v most_o disease_n with_o wild_a sage_n some_o have_v do_v great_a thing_n with_o agrimony_n other_o
proclaim_v their_o ignorance_n and_o glory_v in_o their_o great_a shame_n and_o disgrace_n of_o mankind_n that_o humane_a species_n shall_v have_v any_o such_o unthinking_a brute_n in_o it_o iv_o we_o must_v not_o use_v acid_n in_o the_o preparation_n thereof_o 1._o because_o be_v in_o their_o nature_n opposite_a to_o volatile_a salt_n it_o can_v be_v do_v without_o injury_n to_o the_o sal-volatile-oleosum_a of_o opium_n 2._o because_o they_o can_v so_o well_o agree_v with_o the_o oily_a part_n of_o it_o yet_o be_v they_o not_o so_o much_o to_o be_v blame_v as_o extract_n make_v in_o spirit_n of_o wine_n or_o sulphureous_a menstruum_n because_o acid_a menstruum_n leave_v the_o rosin_n behind_o they_o untouched_a or_o not_o extract_v v._o a_o salino-volatile_a menstruum_fw-la as_o spirit_n of_o sal_fw-la ammoniac_a of_o urine_n etc._n etc._n be_v not_o so_o proper_a 1._o it_o may_v render_v the_o sal-volatile-oleosum_a of_o opium_n too_o acrimonious_a 2._o because_o by_o its_o volatility_n acrimony_n etc._n etc._n it_o may_v cause_v too_o great_a a_o stir_n in_o the_o blood_n etc._n etc._n and_o so_o oppose_v or_o hinder_v sleep_n which_o be_v one_o of_o the_o most_o happy_a and_o useful_a effect_n of_o opium_n or_o it_o be_v sal-volatile-oleosum_a 3._o because_o it_o may_v have_v undue_a effect_n by_o alter_v its_o general_a disposition_n nay_o vi_o we_o be_v not_o to_o use_v a_o lixivial_a menstruum_fw-la though_o so_o much_o cry_v up_o 1._o because_o it_o extract_v the_o resinous_a part_n which_o experto_fw-la crede_fw-la roberto_n i_o have_v find_v to_o be_v pernicious_a upon_o that_o account_n like_o extract_n in_o spirit_n of_o wine_n unless_o great_a care_n be_v take_v to_o separate_v those_o part_n which_o be_v not_o easy_o do_v by_o filtration_n etc._n etc._n 2._o because_o be_v very_o apt_a to_o join_v with_o the_o oily_a part_n and_o quite_o to_o destroy_v their_o nature_n by_o convert_v it_o into_o a_o kind_n of_o sapo_n it_o may_v deal_v so_o with_o some_o of_o the_o oily_a part_n of_o the_o sal-volatile-oleosum_a of_o opium_n 3._o because_o there_o be_v no_o need_n to_o run_v any_o of_o these_o hazard_n since_o the_o sal-volatile-oleosum_a may_v be_v as_o i_o shall_v show_v easy_o extract_v in_o its_o purity_n without_o those_o trouble_n and_o danger_n 4._o because_o any_o tincture_n make_v thus_o be_v apt_a to_o let_v go_v the_o rosin_n at_o stomach_n if_o it_o be_v dilute_v with_o aqueous_a moisture_n take_v before_o with_o it_o or_o after_o it_o which_o so_o be_v let_v go_v coalesces_fw-la and_o do_v mischief_n vii_o the_o use_n of_o fire_n any_o way_n beside_o that_o of_o its_o torrefaction_n be_v much_o to_o be_v suspect_v 1._o because_o the_o sal-volatile-oleosum_a may_v be_v in_o some_o measure_n thereby_o evaporate_v or_o 2._o an_fw-mi empyreum_fw-la contract_v and_o 3._o the_o rosin_n as_o be_v say_v of_o its_o torrefaction_n grow_v the_o more_o in_o proportion_n if_o any_o of_o the_o sal-volatile-oleosum_a or_o but_o the_o phlegm_n be_v by_o that_o mean_n evaporate_v and_o the_o remainder_n keep_v for_o use_v and_o particular_o viii_o the_o distillation_n thereof_o may_v cause_v mighty_a alteration_n in_o its_o property_n strength_n etc._n etc._n we_o must_v therefore_o avoid_v all_o these_o way_n of_o prepare_v it_o and_o yet_o must_v we_o 1._o separate_a the_o sal-volatile-oleosum_a of_o opium_n from_o all_o its_o rosin_n earth_n filth_n and_o dross_n 2._o no_o way_n weaken_v it_o alter_v it_o or_o add_v new_a quality_n thereto_o but_o preserve_v this_o most_o noble_a and_o inestimable_a medicament_n in_o its_o purity_n and_o sincerity_n to_o this_o end_n rain_n water_v distil_v use_v cold_a answer_v all_o intent_n for_o 1._o it_o ready_o imbibe_v the_o sal-volatile-oleosum_a of_o opium_n without_o fire_n heat_v lixivial_a salt_n as_o salt_n of_o tartar_n etc._n etc._n 2._o it_o imbibe_v none_o of_o the_o rosin_n of_o the_o opium_n but_o let_v it_o all_o subside_n together_o with_o the_o earthy_a and_o drossy_a part_n separate_v the_o light_a filth_n if_o there_o be_v any_o to_o the_o surface_n 3._o it_o no_o way_n weaken_v alter_v or_o add_v any_o new_a quality_n to_o the_o sal-volatile-oleosum_a 4._o whatever_o cold_a water_n dissolve_v which_o be_v the_o general_n drink_v or_o menstruum_fw-la appoint_v by_o the_o alwise_a creater_n for_o the_o dissolution_n of_o all_o thing_n take_v into_o the_o stomach_n of_o animal_n be_v easy_o dissolve_v at_o stomach_n by_o its_o more_o powerful_a and_o agreeable_a menstruum_fw-la and_o not_o only_o so_o but_z 5._o water_n itself_o be_v a_o mighty_a stomachick_n and_o causer_n of_o digestion_n as_o hypocrates_n positive_o declare_v l._n 6._o epidem_fw-la sect._n 4._o but_o there_o be_v no_o need_n of_o quote_v hypocrates_n in_o so_o notorious_a a_o thing_n daily_a experience_n tell_v we_o the_o same_o do_v not_o all_o animal_n by_o its_o help_n digest_v their_o food_n do_v not_o all_o mineral_n water_n scarce_o any_o except_v create_v a_o appetite_n and_o cause_n digestion_n even_o when_o no_o such_o effect_n can_v be_v attribute_v to_o the_o mineral_n they_o contain_v than_o which_o they_o do_v also_o as_o may_v be_v very_o easy_o prove_v more_o good_a general_o speak_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d for_o which_o and_o many_o more_o reason_n it_o be_v great_a neglect_n and_o folly_n that_o it_o be_v not_o more_o use_v for_o extract_n etc._n etc._n for_o then_o they_o ready_o dissolve_v at_o stomach_n and_o thereby_o 〈◊〉_d and_o speedy_o take_v effect_n give_v it_o the_o least_o 〈◊〉_d and_o disturbance_n that_o may_v be_v as_o be_v experimental_o find_v in_o that_o of_o aloe_n scammony_n briony_n 〈◊〉_d agariâ—_n 〈◊〉_d coloquintida_n sena_n and_o what_o not_o unless_o the_o virtue_n lie_v in_o the_o resinous_a parâ—s_n for_o then_o sulphureous_a or_o lixivial_a menstruum_n be_v convenient_a how_o inconvenient_a be_v they_o then_o when_o the_o evil_a or_o mischief_n lie_v therein_o as_o in_o our_o case_n 6._o it_o be_v not_o to_o be_v doubt_v but_o water_n general_o imbibe_v what_o be_v best_a and_o most_o agreeable_a to_o our_o body_n it_o be_v the_o general_n menstruum_fw-la appoint_v by_o wisdom_n itself_o for_o that_o use_v and_o to_o be_v the_o vehicle_n of_o what_o be_v best_a in_o all_o our_o food_n etc._n etc._n to_o the_o blood_n however_o there_o can_v be_v no_o doubt_n of_o what_o main_o concern_v we_o at_o present_a its_o most_o ready_a dissolve_v our_o panacea_fw-la in_o the_o stomach_n that_o do_v it_o out_o of_o it_o when_o cold_a without_o the_o convenient_a digestive_a heat_n and_o powerful_a menstruum_fw-la that_o it_o find_v there_o therefore_o take_v of_o distil_a rain-water_n 24_o ounce_n of_o choice_a opium_n slice_v thin_a 8_o ounce_n put_v they_o together_o in_o a_o strong_a glass_n vessel_n of_o bottle-metal_n that_o contain_v about_o 3_o piâ—ts_n let_v it_o be_v of_o a_o tall_a figure_n with_o a_o mouth_n that_o convenient_o receive_v a_o cork_n a_o large_a glass_n bottle_n may_v serve_v the_o turn_n cork_n it_o so_o as_o the_o cork_n may_v be_v easy_o take_v out_o shake_v it_o 3_o or_o 4_o time_n a_o day_n for_o 6_o day_n and_o keep_a it_o in_o a_o place_n free_a from_o frost_n or_o any_o very_a sensible_a degree_n of_o heat_n which_o be_v perform_v lie_v the_o vessel_n side-long_a for_o 24_o hour_n long_o and_o afterward_o decant_v and_o filter_n your_o tincture_n which_o will_v be_v of_o a_o ruby_n colour_n and_o put_v it_o into_o a_o glass_n bottle_n of_o such_o a_o bigness_n as_o that_o it_o may_v fill_v it_o within_o a_o small_a matter_n of_o the_o cork_n and_o so_o let_v it_o stand_v for_o 3_o or_o 4_o day_n then_o poâ—r_v off_o some_o of_o the_o surface_n of_o it_o and_o instead_o thereof_o put_v sweet_a oil_n thereon_o let_v the_o vessel_n have_v a_o convenient_a dust_n or_o pipe_n in_o the_o side_n thereof_o to_o empty_v it_o out_o upon_o occasion_n this_o i_o call_v the_o liquid_a panacea_fw-la of_o opium_n to_o the_o faeces_fw-la add_v a_o pint_n of_o cold_a distil_a water_n shake_v the_o vessel_n as_o before_o 3_o or_o 4_o time_n in_o the_o day_n let_v it_o stand_v on_o it_o 24_o hour_n and_o in_o the_o morning_n decant_v it_o into_o another_o vessel_n repeat_v the_o same_o quantity_n of_o distil_a rain-water_n till_o the_o opium_n no_o long_o tinge_v it_o or_o very_o inconsiderable_o in_o 24_o hour_n at_o last_o you_o may_v use_v water_n keep_v hot_a by_o a_o fire_n &c_n &c_n the_o better_a to_o extract_v the_o remain_v sal-volatile-oleosum_a evaporate_v all_o these_o last_o water_n in_o balneo_fw-la to_o the_o consistence_n of_o a_o extract_n this_o i_o call_v the_o solid_a panacea_fw-la of_o opium_n god_n and_o nature_n act_v by_o simple_a mean_n and_o nothing_o in_o imitation_n of_o they_o be_v more_o commendable_a in_o a_o medicament_n than_o simplicity_n therefore_o i_o shall_v add_v nothing_o to_o the_o panacea_n but_o whole_o
its_o stay_n or_o indigestibleness_n all_o regard_n must_v be_v have_v in_o the_o preparation_n thereof_o as_o be_v in_o the_o follow_a preparation_n which_o be_v therefore_o safe_a chap._n xxvii_o show_v the_o best_a preparation_n of_o opium_n where_o to_o find_v they_o and_o what_o be_v their_o respective_a dose_n etc._n etc._n you_o may_v infer_v out_o of_o the_o premise_n which_o be_v the_o best_a preparation_n of_o opium_n viz._n 1._o such_o as_o have_v the_o resinous_a part_n of_o opium_n separate_v from_o they_o as_o 1._o the_o liquid_a panacea_fw-la of_o opium_n describe_v in_o c._n 25._o of_o this_o book_n 2._o the_o solid_a panacea_fw-la of_o opium_n describe_v in_o c._n 25._o of_o this_o book_n 3._o diacodium_fw-la or_o sir_n e_o mecon_fw-mi in_o the_o london_n dispensatory_a 4._o laudanum_n liquidum_fw-la cydoniatum_n in_o experience_a mr._n wilson_n chemistry_n and_o in_o curious_a mr._n staphurst_n officina_fw-la chymica_fw-la londinensis_fw-la note_v that_o there_o be_v several_a needless_a proceed_n in_o this_o preparation_n as_o that_o of_o put_v yeast_n to_o it_o etc._n etc._n let_v your_o aim_n in_o make_v it_o be_v to_o separate_v the_o resinous_a part_n therefore_o instead_o of_o two_o expression_n direct_v use_v only_o a_o careful_a decantation_n because_o the_o rosin_n may_v pass_v by_o express_v it_o 5._o wedelius_n laudanum_n which_o be_v his_o opilogia_n l._n 1._o sect._n 2._o cap._n 2._o p._n 65._o note_v that_o the_o spumou_n part_v on_o the_o surface_n be_v to_o be_v take_v off_o and_o the_o clear_a tincture_n to_o be_v decant_v from_o the_o faeces_fw-la and_o afterward_o evaporate_v in_o balneo_fw-la to_o the_o consistence_n of_o a_o extract_n 6._o le_fw-fr mort's_n extract_n out_o of_o rain-water_n which_o you_o have_v in_o the_o most_o learned_a dr._n love_n collectanea_fw-la chymica_fw-la p._n 304._o ii_o such_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n be_v alter_v and_o as_o it_o be_v soapify_v by_o lixivial_a salt_n or_o soaps_o viz._n 1._o dr._n starkey_n or_o matthews_n piâ—l_o which_o you_o have_v in_o mr._n wilson_n chemistry_n p._n 271_o 272._o in_o ingenious_a mr._n shipton_n pharmacopâ—ia_n bateana_n among_o the_o pill_n and_o in_o mr._n staphurst_n officina_fw-la chymica_fw-la londinensis_fw-la among_o the_o laudanum_n p_o 51._o note_v that_o the_o main_a thing_n to_o be_v regard_v in_o 〈◊〉_d make_v up_o of_o this_o pill_n be_v 1._o to_o spare_v no_o labour_n in_o pound_v subdue_a and_o intimate_o mix_v the_o sapo_n tartareus_fw-la and_o the_o opium_n 2._o that_o the_o sapo_n shall_v be_v twice_o as_o much_o as_o the_o opium_n that_o it_o may_v the_o better_o subdue_v the_o resinous_a part_n of_o the_o opium_n note_v that_o as_o to_o the_o other_o thing_n contain_v in_o the_o â—aid_a pill_n they_o may_v or_o other_o thing_n be_v add_v or_o omit_v according_a to_o the_o intention_n of_o the_o physician_n only_o this_o i_o say_v that_o it_o be_v very_o convenient_a other_o thing_n shall_v be_v add_v to_o the_o sapo_n and_o opium_n the_o better_a to_o separate_v and_o disgregate_v the_o part_n of_o the_o opium_n as_o have_v be_v intimate_v note_v that_o if_o the_o mass_n be_v too_o dry_a you_o may_v as_o mr._n wilson_n direct_v use_v some_o of_o the_o oil_n that_o separate_v from_o the_o soap_n or_o rectify_v oil_n of_o turpentine_n q._n s._n to_o moisten_v it_o 2._o dr._n bates_n pacific_a pill_n which_o you_o have_v among_o the_o pill_n in_o mr._n shipton_n pharmacopâ—ia_n bateana_n note_v that_o the_o same_o thing_n be_v to_o be_v observe_v as_o to_o this_o and_o starkey_n pill_n in_o all_o particular_n note_v that_o the_o benjamin_n shall_v be_v omit_v as_o be_v resinous_a iii_o such_o preparation_n of_o opium_n wherein_o its_o resinous_a part_n remain_v unaltered_a in_o themselves_o yet_o so_o divide_v separate_a etc._n etc._n as_o to_o be_v render_v innocent_a such_o be_v all_o which_o you_o have_v in_o the_o london_n dispensatory_a 1._o venice_n treacle_n 2._o philoneum_fw-la persicum_fw-la 3._o philoneum_fw-la romanum_fw-la 4._o diascordiuâ—_n 5._o mithridate_n note_v that_o in_o all_o these_o preparation_n the_o opium_n shall_v be_v careful_o mix_v with_o the_o other_o ingredient_n and_o to_o that_o end_n either_o torrify_v and_o fine_o powder_v or_o dissolve_v in_o water_n which_o divide_v all_o its_o part_n and_o then_o thorough_o mix_v with_o the_o other_o ingredient_n while_o it_o be_v off_o or_o after_o it_o be_v reduce_v by_o evaporation_n to_o the_o consistence_n of_o a_o syrup_n or_o somewhat_o thin_a 6._o sydenbam_n laudanum_n which_o you_o will_v find_v in_o mr._n wilson_n chemistry_n note_v that_o the_o main_a care_n in_o this_o preparation_n be_v to_o let_v the_o liquor_n have_v a_o sufficient_a time_n to_o clear_v from_o the_o fâ—ces_n and_o to_o separate_v from_o it_o that_o you_o may_v by_o that_o mean_n have_v less_o of_o the_o rosin_n note_v that_o this_o be_v best_a give_v in_o a_o spirituous_a liquid_a lest_o its_o rosin_n though_o it_o can_v have_v much_o in_o it_o if_o well_o decant_v be_v precipitate_v at_o stomach_n note_v that_o the_o henbane-seed_n in_o the_o philonium_n shall_v be_v leave_v out_o 1._o because_o it_o make_v the_o do_v more_o uncertain_a 2._o because_o it_o be_v not_o to_o be_v esteem_v so_o much_o as_o opium_n at_o least_o you_o multiply_v thing_n without_o necessity_n in_o put_v it_o in_o note_v that_o pil._n e_fw-la cynoglosso_fw-la as_o be_v say_v in_o the_o last_o chapter_n of_o pil._n e_o styrace_n be_v a_o very_a ill_a composition_n both_o upon_o the_o account_n of_o the_o resinous_a thing_n that_o it_o contain_v as_o also_o the_o resinous_a preparation_n of_o opium_n that_o it_o be_v make_v of_o and_o therefore_o do_v as_o that_o e_z styrace_n often_o cause_v grievous_a effect_n nor_o do_v i_o think_v the_o london_n laudanum_n who_o name_n do_v probable_o recommend_v it_o more_o than_o any_o thing_n else_o worthy_a a_o place_n among_o the_o best_a and_o safe_a preparation_n because_o the_o opium_n be_v render_v worse_o or_o more_o resinous_a than_o the_o crude_a by_o be_v extract_v out_o of_o spirit_n of_o wine_n and_o because_o it_o have_v too_o few_o other_o ingredient_n to_o divide_v segregate_v and_o keep_v its_o resinous_a part_n from_o coalescence_n so_o that_o it_o may_v and_o sometime_o do_v cause_n ill_a symptom_n so_o philonium_fw-la magistrale_fw-la be_v to_o be_v reject_v for_o the_o like_a reason_n beside_o that_o it_o be_v otherwise_o a_o foolish_a preparation_n because_o opium_n benjamin_n myrrh_n and_o mummy_n be_v order_v to_o be_v make_v a_o opiate_n or_o electuary_n with_o spirit_n of_o wine_n which_o be_v ridiculous_a so_o troch_v the_o carabe_n and_o de_fw-fr terra_fw-la lemnia_n be_v not_o without_o their_o fault_n because_o one_o have_v frankincense_n and_o the_o other_o olibanum_fw-la in_o it_o which_o be_v resinous_a though_o but_o in_o a_o small_a quantity_n seif_n de_fw-mi thure_z have_v a_o great_a quantity_n of_o the_o frankincense_n be_v not_o commendable_a since_o the_o opium_n be_v also_o crude_a now_o have_v show_v you_o which_o be_v the_o best_a and_o worst_a preparation_n and_o why_o it_o remain_v that_o i_o show_v you_o the_o just_a dose_n of_o the_o best_a and_o soft_a who_o number_n be_v very_o sufficient_a to_o answer_v all_o intent_n without_o meddle_v with_o such_o as_o may_v not_o be_v so_o saâ—e_v or_o neat_a a_o explanation_n of_o the_o table_n of_o dose_n i_o have_v once_o add_v a_o explicatory_a table_n of_o the_o mark_v i_o use_v but_o afterward_o consider_v that_o all_o physician_n and_o good_a practitioner_n in_o physic_n do_v know_v they_o and_o that_o it_o be_v not_o fit_a to_o intrust_v other_o therewith_o therefore_o i_o shall_v only_o add_v something_o for_o the_o better_a and_o ready_a use_n of_o the_o premise_a table_n of_o dose_n 1._o note_v that_o the_o sort_n of_o person_n that_o you_o have_v to_o deal_v with_o be_v place_v in_o the_o uppermost_a space_n of_o the_o say_a table_n and_o the_o dose_n fit_a for_o such_o and_o such_o person_n put_v direct_o under_o they_o in_o the_o same_o column_n 2._o note_v that_o there_o be_v three_o sort_n of_o dose_n of_o every_o particular_a preparation_n that_o be_v the_o least_o middle_a and_o high_a do_v under_o every_o sort_n of_o man_n or_o woman_n which_o be_v also_o of_o three_o sort_n the_o strong_a middling_a and_o weak_a as_o you_o see_v in_o the_o upper_a space_n 3._o note_v therefore_o that_o when_o yond_o be_v about_o to_o give_v a_o opiate_n to_o any_o man_n or_o woman_n that_o you_o first_o look_n in_o that_o upper_a space_n for_o the_o sort_n of_o person_n you_o be_v to_o give_v it_o to_o as_o weak_a strong_a or_o middling_a man_n or_o woman_n then_o carry_v your_o eye_n down_o in_o that_o column_n till_o you_o come_v over_o against_o the_o preparation_n that_o you_o intend_v to_o give_v and_o there_o you_o will_v find_v in_o
the_o say_a column_n three_o sort_n of_o dose_n the_o low_a on_o the_o left_a hand_n the_o high_a on_o the_o right_a hand_n and_o the_o moderate_a do_v between_o they_o as_o suppose_v you_o be_v about_o to_o give_v a_o middle_n do_v of_o the_o liquid_a panacea_fw-la to_o a_o strong_a man_n see_v for_o strong_a man_n in_o the_o upper_a space_n and_o for_o liquid_a panacea_fw-la in_o the_o first_o column_n on_o the_o left_a hand_n under_o the_o word_n opiate_n and_o where_o the_o column_n that_o belong_v to_o strong_a man_n and_o the_o space_n that_o belong_v to_o liquid_a panacea_fw-la do_v meet_v there_o you_o will_v find_v qt_n 20_o 30_o 40_o for_o the_o least_o middle_a and_o high_a do_v give_v which_o you_o think_v fit_a according_a to_o your_o intention_n so_o if_o you_o be_v about_o to_o give_v the_o high_a do_v of_o the_o solid_a panacea_fw-la to_o a_o strong_a woman_n you_o will_v find_v under_o the_o word_n strong_a woman_n over_o against_o solid_a panacea_fw-la gr_fw-la i_o gr_n i¼_n gr_n i_o ss_z which_o show_v you_o that_o gr_n i_o ss_z be_v the_o high_a do_v for_o a_o strong_a woman_n and_o so_o of_o all_o the_o rest_n 4._o note_v that_o i_o have_v be_v so_o cautious_a in_o dose_v all_o the_o opiate_n that_o you_o may_v very_o safe_o give_v the_o high_a dose_n to_o all_o but_o very_o weak_a person_n to_o who_o it_o be_v hardly_o fit_a to_o give_v any_o thing_n by_o reason_n of_o extreme_a weakness_n 5._o note_v that_o if_o you_o give_v any_o to_o young_a person_n under_o the_o age_n of_o 20._o you_o shall_v proportion_v the_o dose_n not_o so_o much_o as_o idle_a custom_n direct_v according_a to_o their_o year_n as_o bulk_n and_o strength_n for_o instance_n allow_v strong_a man_n to_o be_v 200_o pound_n weight_n you_o must_v give_v a_o strong_a youth_n of_o 100_o pound_v weight_n half_o the_o do_v of_o the_o strong_a man_n and_o so_o of_o all_o other_o only_o allow_v somewhat_o less_o the_o young_a they_o be_v because_o of_o the_o softness_n fineness_n or_o laxity_n of_o their_o texture_n especial_o if_o they_o be_v very_o young_a to_o who_o opiate_n must_v be_v cautious_o give_v or_o only_o diacodium_fw-la which_o be_v best_a in_o that_o case_n and_o that_o in_o a_o small_a proportion_n also_o for_o young_a child_n can_v bear_v opiate_n as_o well_o as_o grow_v person_n no_o not_o in_o proportion_n to_o their_o bulk_n or_o weight_n place_v this_o between_o p._n 294_o and_o p._n 295._o a_o table_n of_o the_o dose_n of_o the_o best_a and_o safe_a opiate_n opiate_n do_v do_v do_v do_v liquid_a to_o strong_a man_n to_o middling_a man_n &_o strong_a woman_n to_o weak_a man_n &_o middling_a woman_n to_o weak_a woman_n the_o liquid_a panacea_fw-la gt_fw-mi 20_o 30_o 40_o 16_o 23_o 30_o 12_o 18_o 24_o 10_o 15_o 20_o laudanum_n liquidum_fw-la cydoniatum_n gt_fw-fr 20_o 30_o 40_o 16_o 23_o 30_o 12_o 18_o 24_o 10_o 15_o 20_o sydenham_n laudanum_n gt_v 20_o 30_o 40_o 16_o 23_o 30_o 12_o 18_o 24_o 10_o 15_o 20_o diacodium_fw-la or_o syr._n e_fw-it mecon_fw-mi ☞_o i_o Ê’x_o ☞_o ss_z ☞_o ss_z Ê’vi_fw-la ☞_o i_o ☞_o ss_z Ê’v_o Ê’vi_fw-la Ê’iii_fw-la ☞_o ss_z Ê’v_v solid_n  _fw-fr  _fw-fr  _fw-fr  _fw-fr the_o solid_a panacea_fw-la gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ay_o i¼_n gr_n ss_z ¾_n i_o wedelius_n laudanum_n gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ay_o i¼_n gr_n ss_z ¾_n i_z le_fw-fr mort_n extract_n gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ay_o i¼_n gr_n ss_z ¾_n i_o dr._n bate_n pacific_a pill_n gr_n two_o iiss_n three_o gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ¾_n ay_o starkey_n or_o matthew_n pill_n gr_n vi_fw-la ix_o twelve_o gr_n v_o seven_o ix_o gr_n four_o vi_fw-la viij_o gr_n three_o four_o v_a philonium_fw-la romanum_fw-la Ê’ss_n ℈_o two_o Ê’i_fw-la ℈_o i_o Ê’ss_n ℈_o two_o gr_n xviii-xxiv_a Ê’ss_v gr_n xuj_o xx_o xxiv_o philonium_fw-la persicum_fw-la Ê’ss_n ℈_o two_o Ê’i_fw-la ℈_o i_o Ê’ss_o ℈_o two_o gr_n xviii-xxiv_a Ê’ss_v gr_n xuj_o xx_o xxiv_o venice_n treacle_n Ê’i_fw-it Ê’ii_fw-la Ê’iii_fw-la Ê’i_fw-la Ê’iss_v Ê’ii_fw-la ℈_o two_o Ê’i_fw-la ℈_o iiii_o Ê’ss_n ℈_o two_o Ê’i_fw-la mithridate_n ☞_o ss_z Ê’vi_fw-la ☞_o i_o Ê’iii_fw-la Ê’v_o Ê’vii_fw-la Ê’ii_fw-la ☞_o ss_z Ê’vi_fw-la Ê’ii_fw-la Ê’iii_fw-la ☞_o ss_z diascordium_fw-la ☞_o ss_z Ê’vi_fw-la ☞_o i_o Ê’iii_fw-la Ê’v_o Ê’vii_fw-la Ê’ii_fw-la ☞_o ss_z Ê’vi_fw-la Ê’ii_fw-la Ê’ii_fw-la ☞_o ss_z the_o dose_n of_o london_n laudanum_n which_o i_o mention_v rather_o for_o its_o general_a use_n than_o laudableness_n may_v be_v the_o same_o with_o that_o of_o the_o pacifick_n pill_n a_o table_n of_o mark_n very_o necessary_a for_o the_o better_a understanding_n of_o the_o table_n of_o dose_n gt_fw-fr signify_v a_o drop_n 〈◊〉_d signify_v a_o grain_n 〈◊〉_d signify_v a_o scruple_n which_o be_v 20_o grainâ—_n 〈◊〉_d or_o ☜_o signify_v a_o dram_n which_o be_v 3_o scruple_n 〈◊〉_d signify_v a_o ounce_n which_o be_v 8_o dramâ—_n or_o drachm_n â—_o â—_o signifieâ—_n a_o quarter_n of_o any_o to_n â—_o â—_o â—_o â—_o ss_z or_o ss_z signifieâ—_n half_a of_o any_o to_n â—_o â—_o signifieâ—_n 3_o quarter_n of_o any_o to_a chap._n xxviii_o the_o cure_n of_o the_o ill_a effect_n of_o opium_n have_v show_v how_o to_o prepare_v opium_n so_o as_o to_o render_v it_o safe_a and_o innocent_a in_o a_o moderate_a do_v and_o how_o much_o that_o moderate_a do_v be_v one_o may_v be_v apt_a to_o think_v that_o this_o chapter_n be_v needless_a but_o when_o you_o consider_v how_o many_o there_o be_v that_o may_v be_v negligent_a wilful_a want_v time_n skill_n etc._n etc._n to_o prepare_v it_o or_o take_v too_o much_o or_o too_o long_o of_o it_o and_o that_o the_o physician_n must_v be_v able_a to_o answer_n and_o remedy_n all_o ill_a accident_n that_o may_v happen_v you_o will_v find_v it_o very_o requisite_a that_o i_o shall_v show_v how_o to_o cure_v the_o ill_a effect_n of_o opium_n which_o proceed_v either_o 1._o from_o its_o rosin_n at_o stomach_n or_o 2._o from_o too_o much_o relaxation_n by_o a_o excessive_a do_v or_o 3._o from_o a_o long_a and_o lavish_a use_n of_o it_o or_o 4._o from_o a_o sudden_a leave_v it_o off_o after_o a_o long_a and_o lavish_a use_v thereof_o i._o to_o cure_v the_o ill_a effect_n of_o the_o rosin_n at_o stomach_n you_o be_v first_o to_o know_v whether_o that_o be_v the_o cause_n which_o you_o may_v learn_v 1._o by_o consider_v whether_o crude_a opium_n or_o some_o resinous_a preparation_n thereof_o be_v take_v especial_o by_o itself_o in_o the_o form_n of_o a_o pill_n or_o pill_n as_o a_o extract_v thereof_o out_o of_o spirit_n of_o wine_n or_o pilâ—e_a styrace_n or_o london_n laudanum_n or_o the_o like_a not_o due_o prepare_v as_o have_v be_v direct_v 2._o by_o the_o symptom_n which_o be_v these_o viz._n a_o nausea_n puke_v vomit_v hiccough_n convulsion_n distress_n and_o anxiety_n about_o the_o stomach_n particular_o the_o part_n call_v the_o pit_n of_o the_o stomach_n swimmings_n in_o the_o head_n vertigo_n palpitation_n and_o tremble_n of_o the_o heart_n agitation_n uneasiness_n a_o turbulent_a pulse_n and_o after_o a_o struggle_v of_o nature_n under_o those_o symptom_n faint_n leipothymy_n syncopes_fw-la etc._n etc._n which_o last_o you_o must_v not_o take_v for_o certain_a sign_n and_o symptom_n unless_o the_o former_a have_v precede_v they_o because_o it_o be_v not_o impossible_a but_o they_o may_v happen_v from_o the_o quantity_n of_o the_o opium_n condition_n or_o constitution_n of_o the_o person_n etc._n etc._n but_o this_o when_o all_o thing_n be_v compare_v together_o will_v be_v easy_o judge_v of_o especial_o if_o you_o observe_v 1._o whether_o those_o faint_n or_o leipothymy_n be_v not_o more_o like_o the_o failure_n and_o stupor_n of_o drunkard_n than_o bare_a faint_n if_o they_o be_v of_o the_o first_o sort_n then_o do_v they_o proceed_v from_o a_o over_o relaxation_n occasion_v by_o the_o opium_n and_o not_o from_o its_o rosin_n the_o cure_n of_o which_o belong_v to_o the_o second_o particular_a 2._o whether_o they_o be_v more_o attend_v with_o the_o sign_n of_o relaxation_n as_o deadness_n of_o the_o eye_n falter_v of_o the_o tongue_n darkness_n before_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la efflorescence_n of_o the_o skin_n laxity_n of_o the_o limb_n want_v of_o feel_v stupidity_n sleepiness_n failure_n of_o the_o sense_n or_o of_o make_v water_n loss_n of_o memory_n or_o understanding_n a_o dry_a mouth_n a_o slow_a and_o wide_a pulse_n and_o other_o thing_n much_o like_o the_o state_n of_o a_o deadish_a drunkenness_n for_o then_o those_o failure_n be_v the_o effect_n of_o relaxation_n by_o the_o pleasant_a sensation_n that_o the_o opium_n cause_n but_o after_o all_o it_o be_v the_o sort_n of_o opium_n that_o be_v take_v and_o
that_o when_o people_n be_v in_o a_o untoward_a condition_n or_o as_o they_o call_v it_o out_o of_o sod_n the_o next_o day_n after_o drink_v man_n often_o advise_v take_v the_o hair_n of_o the_o same_o dog_n that_o be_v drink_v some_o of_o the_o same_o wine_n or_o liquor_n it_o be_v best_o for_o they_o to_o use_v it_o as_o i_o just_a now_o direct_v for_o their_o case_n upon_o the_o good_a effect_n of_o the_o wine_n cease_v be_v much_o like_a that_o upon_o the_o go_n off_o of_o the_o operation_n of_o opium_n which_o may_v also_o in_o this_o case_n be_v use_v instead_o of_o wine_n to_o procure_v a_o better_a and_o blither_n condition_n for_o that_o day_n that_o use_v to_o be_v very_o troublesome_a to_o drinker_n 3._o note_v that_o good_a preparation_n of_o opium_n may_v be_v convenient_o use_v to_o horse_n to_o prevent_v their_o be_v tire_v or_o take_v off_o their_o weariness_n and_o cause_v they_o to_o go_v on_o but_o i_o will_v not_o advise_v any_o preparation_n in_o this_o case_n but_o the_o liquid_a panacea_fw-la in_o good_a ale_n or_o beer_n and_o that_o only_a in_o the_o same_o quantity_n as_o be_v use_v to_o man_n till_o far_a experience_n embolden_v the_o practice_n by_o such_o mean_n i_o can_v doubt_v it_o any_o jade_n may_v be_v make_v to_o appear_v lively_a go_v well_o etc._n etc._n chap._n xxxii_o of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o compose_v the_o sensitive_a soul_n spirit_n etc._n etc._n i_o have_v show_v how_o and_o why_o it_o compose_v and_o quiet_v the_o sensitive_a soul_n spirit_n blood_n stomach_n etc._n etc._n and_o by_o that_o mean_n allay_v all_o the_o fury_n commotion_n perturbation_n and_o turbulent_a exorbitance_n thereof_o and_o that_o often_o without_o sleep_n but_o much_o better_a with_o it_o it_o follow_v therefore_o 1._o that_o it_o prevent_v and_o take_v off_o all_o fret_n and_o turbulent_a passion_n of_o the_o sensitive_a soul_n as_o anger_n uneasy_a agitation_n and_o toss_v of_o the_o mind_n peevishness_n fretfulness_n discontent_n disquietude_n dissatisfaction_n murmur_n turmoiling_n and_o vexatious_a thought_n anxiety_n solicitude_n etc._n etc._n and_o all_o the_o evil_a effect_n thereof_o as_o watch_n waste_v of_o spirit_n or_o strength_n lossitude_n hypochondriacal_a melancholy_n cachexy_n scurvy_n etc._n etc._n but_o these_o last_o belong_v most_o proper_o to_o its_o alterative_a faculty_n or_o virtue_n 2._o all_o involuntary_a furious_a agitation_n of_o the_o sensitive_a soul_n and_o spirit_n as_o madness_n more_o especial_o melancholy_a madness_n or_o such_o as_o proceed_v from_o grievous_a thought_n or_o apprehension_n loss_n cross_n despair_n fear_n terror_n or_o the_o like_a but_o they_o be_v not_o so_o good_a in_o merry_a madness_n as_o those_o from_o joy_n venereal_a fury_n and_o suchlike_a which_o answer_v the_o great_a dispute_n about_o opiate_n in_o madness_n delirium_n epileptical_a fit_n convulsion_n general_a and_o particular_a as_o those_o of_o the_o head_n rise_v of_o the_o light_n vomit_n hiccough_n sabbing_n kecking_n convulsive_a asthma_n palpitation_n and_o tremble_n of_o the_o heart_n shake_v and_o shivering_n upon_o fear_n terror_n cold_a pain_n ague-fits_a convulsive_a colick_n hysterick_n fit_v iliack_a passion_n etc._n etc._n 3._o all_o fever_n and_o fret_n of_o humour_n that_o happen_v from_o any_o of_o the_o aforesaid_a cause_n or_o from_o any_o violent_a motion_n voluntary_a or_o involuntary_a as_o labour_n run_v hew_v fight_a or_o any_o vehement_a exercise_n ratling_n toss_n concussion_n in_o coach_n wagon_n boat_n in_o stormy_a wether_n violent_a ride_v etc._n etc._n or_o from_o heat_n of_o fire_n sun_n bath_n hothouse_n bagnio_n crowd_n lie_v too_o many_o in_o one_o bed_n or_o with_o too_o much_o clothes_n or_o from_o grievous_a sensation_n irritation_n or_o pain_n as_o fever_n upon_o inflammation_n abscess_n bubo_n stone_n colic_n cardialgia_n wound_n fracture_n dislocation_n confusion_n amputation_n lithotomy_n paracentesis_n or_o any_o painful_a operation_n of_o the_o noble_a art_n of_o chirurgery_n agony_n or_o pain_n of_o the_o smallpox_n as_o its_o second_o fever_n and_o the_o like_a or_o from_o flux_n as_o tedious_a and_o turbulent_a vomit_n diarrheas_n dysentery_n cholera_n iliack_a passion_n artificial_a purge_v and_o all_o symptomatick_a or_o immaterial_a fever_n whatsoever_o which_o either_o never_o have_v any_o matter_n but_o proceed_v from_o such_o agitate_a cause_n as_o i_o mention_v or_o remain_v as_o some_o do_v after_o the_o grieve_v matter_n be_v carry_v off_o by_o vomit_v purge_v etc._n etc._n i_o forbear_v mention_v pleurisy_n and_o peripneumonia_n among_o the_o fever_n that_o it_o prevent_v or_o take_v off_o because_o there_o be_v great_a dispute_n whether_o opiate_n be_v convenient_a in_o those_o case_n which_o i_o hope_v to_o determine_v unless_o it_o be_v when_o the_o say_v distemper_n be_v come_v to_o that_o pass_n that_o it_o be_v dangerous_a to_o cause_v sleep_n or_o take_v away_o any_o of_o the_o sense_n of_o the_o irritation_n of_o the_o matter_n to_o be_v expectorate_v lest_o it_o shall_v be_v too_o much_o amass_v in_o the_o bronchias_n or_o windpipe_n and_o so_o choke_v the_o person_n i_o see_v no_o cause_n to_o forbid_v they_o any_o more_o than_o sleep_v or_o opiate_n in_o other_o inflammation_n wherein_o they_o be_v high_o beneficial_a to_o give_v ease_n cause_n sleep_n compose_v the_o spirit_n and_o take_v off_o or_o at_o least_o moderate_a the_o fever_n but_o i_o see_v many_o good_a reason_n to_o use_v they_o 1._o because_o as_o a_o sal-volatile-oleosum_a they_o reserate_v and_o resolve_v clammy_a humour_n and_o be_v so_o agreeable_a in_o principle_n as_o menstraums_n shall_v be_v to_o the_o thing_n to_o be_v resolve_v i_o can_v doubt_v but_o red_a poppy_n be_v upon_o experience_n state_v a_o specific_a in_o those_o case_n for_o that_o reason_n 2._o because_o these_o distemper_n as_o hypocrates_n speak_v be_v from_o a_o segregation_n of_o humour_n by_o agitation_n etc._n etc._n and_o opiate_n excellent_a composer_n thereof_o 3._o because_o they_o be_v such_o great_a discusser_n and_o 4._o open_v the_o pore_n to_o let_v the_o discuss_v matter_n quite_o out_o of_o the_o body_n 5._o because_o it_o may_v be_v that_o by_o its_o relaxation_n upon_o such_o resolution_n the_o lodge_v matter_n may_v be_v cause_v to_o flow_v off_o and_o circulate_v again_o and_o so_o be_v gradue_v discuss_v and_o carry_v off_o by_o the_o open_a pore_n 6._o because_o it_o envigorate_v nature_n to_o perform_v those_o thing_n and_o 7._o give_v ease_n and_o recruit_v of_o the_o spirit_n by_o sleep_n so_o that_o all_o thing_n consider_v i_o think_v as_o experience_n assure_v we_o that_o red_a poppy_n or_o opiate_n in_o due_a quantity_n be_v the_o very_o best_a remedy_n that_o can_v be_v use_v hence_o it_o be_v that_o wedelius_n call_v opium_n a_o antipleuritick_n specific_a he_o have_v observe_v as_o i_o and_o other_o have_v do_v that_o the_o whole_a course_n of_o the_o disease_n and_o expectoration_n will_v succeed_v much_o better_a by_o their_o use._n he_o add_v also_o that_o he_o have_v very_o often_o cure_v they_o by_o its_o help_n without_o let_v of_o blood_n which_o be_v a_o infallible_a sign_n of_o their_o good_a effect_n since_o the_o pleurisy_n can_v hardly_o be_v cure_v without_o bleed_v i_o can_v see_v how_o a_o effect_n that_o bear_v such_o analogy_n to_o sleep_n can_v do_v any_o more_o harm_n than_o sleep_n etmuller_n also_o advise_v the_o give_v of_o opiate_n not_o only_o in_o the_o beginning_n but_o also_o during_o the_o increase_n of_o the_o pleurisy_n or_o peripneumoniae_fw-la so_o that_o i_o conclude_v that_o they_o be_v of_o excellent_a use_n in_o those_o disease_n unless_o it_o be_v when_o sleep_n or_o they_o may_v cause_v too_o much_o insensibleness_n of_o the_o bronchias_n and_o so_o retard_v expectoration_n when_o the_o case_n be_v such_o that_o the_o want_v thereof_o may_v endanger_v the_o person_n be_v be_v choke_v we_o have_v also_o many_o history_n of_o person_n cure_v in_o other_o fever_n by_o large_a dose_n of_o opiate_n i_o suppose_v that_o resinous_a opiate_n cause_v vomit_v and_o great_a disturbance_n by_o reason_n of_o ill_a digestion_n in_o those_o case_n may_v be_v one_o great_a cause_n of_o people_n fear_n and_o jeolousy_n in_o give_v opiate_n which_o be_v easy_o prevent_v by_o give_v liquid_a opiate_n void_a of_o any_o resinous_a particle_n as_o the_o liquid_a panacea_fw-la etc._n etc._n 4._o it_o do_v by_o compose_v quiet_v and_o appease_v the_o motion_n and_o perturbation_n of_o the_o blood_n conduce_v much_o to_o the_o stop_n of_o its_o efflux_n in_o hemorrhage_n or_o bleeding_n that_o be_v unnatural_a as_o at_o nose_n in_o spit_v and_o vomit_v of_o blood_n bleed_v at_o the_o hemorrhoid_v in_o dysentery_n piss_v of_o blood_n etc._n etc._n and_o sometime_o in_o profuse_a menses_fw-la when_o they_o happen_v from_o a_o fever_n or_o too_o much_o motion_n of_o the_o blood_n and_o
it_o be_v best_o like_v and_o most_o suitable_a to_o people_n mind_n palate_n etc._n etc._n ii_o the_o do_v moderate_a except_o it_o be_v 1._o where_o some_o by_o accident_n require_v otherwise_o as_o pain_n looseness_n vomit_n and_o to_o titillate_v the_o venereal_a membrane_n because_o remote_a which_o see_v in_o the_o respective_a chapter_n of_o the_o use_n of_o opiate_n in_o those_o case_n 2._o where_o the_o general_a rule_n direct_v otherwise_o as_o in_o the_o soft_a flesh_a people_n child_n woman_n etc._n etc._n where_o the_o do_v must_v be_v less_o iii_o the_o vehicle_n must_v be_v the_o same_o as_o be_v direct_v to_o compose_v but_o in_o old_a people_n it_o be_v observe_v that_o smooth_a spirituous_a thing_n as_o good_a ale_n etc._n etc._n conduce_v very_o much_o to_o cause_v sleep_n because_o sulphur_n do_v qualifie-the_a volatile_a salt_n of_o the_o opium_n as_o be_v show_v iv_o the_o time_n in_o general_n be_v at_o the_o due_a distance_n before_o bedtime_n that_o be_v direct_v in_o the_o general_a rule_n but_o opiate_n may_v be_v give_v at_o any_o time_n when_o the_o case_n require_v as_o in_o the_o smallpox_n about_o 12_o 1_o or_o 2_o in_o the_o afternoon_n according_a as_o the_o â—tions_n which_o happen_v in_o the_o afternoon_n or_o towards_o the_o evening_n do_v seize_v they_o and_o in_o ague_n at_o the_o due_a distance_n before_o the_o paroxysm_n invade_v they_o 〈◊〉_d that_o the_o operation_n thereof_o may_v be_v fall_n and_o complete_a before_o the_o time_n that_o the_o fit_n be_v to_o begin_v and_o so_o in_o all_o other_o câ—ses_n of_o the_o like_a â—ind_n v._o the_o regimen_n in_o this_o 〈◊〉_d 〈◊〉_d 〈◊〉_d twosold_a aspect_n 1._o to_o promote_v 〈◊〉_d 2._o to_o compose_v and_o quiet_a motion_n 〈◊〉_d â—tions_n of_o the_o spirit_n 〈◊〉_d etc._n etc._n 〈◊〉_d 〈◊〉_d quiet_v be_v the_o two_o 〈◊〉_d 〈◊〉_d as_o to_o the_o first_o the_o regimen_n must_v be_v the_o same_o as_o be_v direct_v in_o the_o chapter_n of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o relax_v but_o as_o to_o compose_v and_o quiet_v the_o spirit_n i_o shall_v add_v somewhat_o though_o relaxer_n be_v general_o good_a for_o this_o purpose_n unless_o join_v with_o some_o agitate_v accident_n as_o heat_n or_o the_o like_a 1._o as_o to_o diet_n it_o shall_v consist_v of_o cool_a incrassate_a inviscate_a thing_n that_o be_v not_o aromatic_a acid_a or_o saline_a such_o be_v milk-meat_n emulsion_n almond_n milks_n chicken_n broth_n with_o cool_a herb_n water-gruel_n fresh_a and_o young_a soft_a flesh_n lettuce_n purstane_n spinage_n herb_n mercury_n mallow_n and_o such_o like_a mucilage_n as_o of_o quince_n fleabane_n etc._n etc._n the_o drink_n may_v be_v milk_n and_o water_n whey_n or_o such_o unfermented_a liquor_n or_o smooth_a small_a beer_n not_o too_o old_a for_o all_o stale_a drink_n be_v naught_o water_n where_o it_o agree_v etc._n etc._n 2._o rest_v of_o body_n and_o spirit_n must_v be_v contrive_v by_o all_o mean_n as_o by_o lean_v lie_a or_o sit_v still_o without_o any_o motion_n after_o it_o be_v take_v till_o bedtime_n and_o therefore_o let_v the_o person_n if_o the_o season_n permit_v be_v as_o much_o undress_v as_o may_v be_v in_o a_o loose_a garment_n or_o morning-gown_n all_o that_o time_n and_o be_v help_v off_o with_o his_o clothes_n that_o he_o may_v not_o agitate_v his_o body_n when_o sleepy_a and_o not_o before_o let_v he_o go_v into_o a_o cold_a bed_n in_o summer_n and_o but_o a_o little_a warm_v in_o winter_n and_o only_o have_v what_o bedclothe_n suffice_v and_o please_v he_o best_o and_o then_o lie_v absolute_o still_o without_o noise_n light_z or_o fire_n in_o the_o room_n 3._o rest_v and_o tranquillity_n of_o mind_n be_v very_o necessary_a which_o shall_v be_v not_o only_o free_a from_o grievous_a passion_n but_o from_o all_o excess_n of_o joyous_a one_o which_o too_o much_o agitate_v the_o spirit_n 4._o the_o air_n shall_v be_v moist_a and_o moderate_a and_o if_o not_o such_o by_o the_o wether_n render_v so_o by_o art_n especial_o in_o fever_n 5._o all_o evacuation_n shall_v be_v make_v that_o may_v any_o way_n disturb_v his_o sleep_n before_o he_o betake_v himself_o to_o it_o nor_o shall_v the_o stomach_n be_v over-full_a or_o empty_a lest_o any_o grievance_n may_v be_v thereby_o create_v 6._o emollient_a tepid_a bath_n fomentation_n feetwash_n etc._n etc._n do_v fine_o dispose_v people_n to_o sleep_n but_o take_v care_n they_o be_v not_o too_o hot_a for_o heat_n cause_v a_o stir_n of_o blood_n and_o spirit_n which_o be_v a_o enemy_n to_o sleep_n 1._o note_v that_o long_o sleep_v after_o great_a fatigue_n or_o long_o watch_v ought_v not_o to_o be_v very_o frightful_a if_o the_o do_v be_v moderate_a and_o that_o the_o person_n take_v sustenance_n 2._o note_v that_o old_a or_o dry_a person_n or_o such_o as_o be_v very_o unapt_a to_o sleep_v after_o opiate_n be_v often_o cause_v to_o sleep_v by_o smooth_a wine_n ale_z cowslip_n wine_n or_o the_o like_a because_o the_o gentle_a oiliness_n of_o such_o liquor_n do_v correct_v the_o acrimony_n of_o their_o volatile_a salt_n and_o at_o the_o same_o time_n cause_n a_o sense_n of_o pleasure_n which_o relax_n and_o cause_n sleep_v it_o have_v be_v observe_v that_o even_o ambergrise_v and_o musk_n which_o exagitate_v the_o blood_n and_o spirit_n cause_v old_a man_n to_o sleep_n which_o happen_v by_o their_o fine_a sulphur_n ready_o fasten_v upon_o the_o acrimonious_a volatile_a salt_n as_o spirit_n of_o wine_n do_v upon_o sal_fw-la ammoniac_a which_o be_v mix_v do_v soon_o coagulate_v therefore_o i_o be_o apt_a to_o think_v that_o camphire_n will_v be_v of_o excellent_a use_n to_o correct_v the_o opium_n and_o the_o volatile_a salt_n of_o the_o body_n in_o such_o case_n because_o it_o be_v experimental_o certain_a that_o it_o correct_v the_o acrimony_n of_o urine_n of_o semen_n virile_a cantharides_n etc._n etc._n 3._o note_v that_o the_o dry_a the_o body_n be_v the_o more_o unapt_a be_v opiate_n to_o cause_n sleep_n therefore_o dry_a body_n as_o of_o old_a man_n hectical_a person_n etc._n etc._n shall_v be_v well_o moisten_v by_o incrassative_a moistener_n as_o emulsion_n and_o such_o thing_n as_o be_v above_o mention_v and_o order_v in_o the_o chapter_n of_o the_o relax_a use_n of_o opiate_n from_o what_o be_v say_v i_o do_v conclude_v that_o opiate_n do_v cause_n sleep_v very_o ready_o where_o the_o oily_a part_n abound_v and_o that_o thing_n that_o have_v a_o fine_a oleous_a sulphur_n be_v very_o good_a corrector_n of_o it_o where_o acrimonious_a volatile_a salt_n abound_v in_o order_n to_o cause_n sleep_n and_o that_o hence_o it_o be_v that_o some_o ancient_a people_n will_v often_o sleep_v better_o by_o the_o use_n of_o the_o aforementioned_a smooth_a ferment_v sulphureous_a liquor_n than_o by_o the_o use_n of_o opium_n from_o all_o which_o it_o appear_v that_o sleep_n be_v not_o such_o a_o property_n of_o opium_n as_o people_n make_v it_o to_o be_v because_o that_o beside_o relax_v sleep_v also_o require_v a_o great_a rest_n of_o the_o spirit_n and_o the_o sensitive_a soul_n it_o seem_v very_o probable_a from_o the_o premise_n that_o anodyne_n sulphur_n of_o vitriol_n will_v be_v excellent_a to_o cause_v old_a man_n to_o sleep_n for_o it_o doubtless_o cause_n sleep_v only_o by_o obtund_v and_o qualify_a our_o volatile_a salt_n as_o white_a 〈◊〉_d and_o other_o balsamicks_n will_v often_o do_v chap._n xxxvi_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o stop_v flux_n it_o palliate_v moderate_v and_o stop_v flux_n 1._o by_o take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o cause_n contraction_n to_o squeeze_v they_o out_o and_o promote_v their_o motion_n 2._o because_o it_o compose_v and_o still_v the_o motion_n of_o humour_n by_o the_o relaxation_n and_o the_o sleep_n that_o it_o cause_n which_o quiet_v motion_n 3._o because_o thereby_o and_o by_o its_o combine_a agreeableness_n and_o texture_n it_o congregate_n the_o disgregated_a humour_n 4._o because_o the_o relaxation_n suspend_v the_o humour_n 5._o because_o it_o discuss_n ill_a humour_n 6._o because_o the_o pore_n be_v open_v by_o the_o relaxation_n the_o humour_n that_o cause_v the_o flux_n be_v gradual_o perspire_v by_o that_o most_o natural_a and_o universal_a sort_n of_o evacuation_n for_o it_o be_v plain_a reason_n and_o common_a observation_n that_o a_o plentiful_a evacuation_n at_o pore_n stop_v flux_n per_fw-la anum_fw-la etc._n etc._n and_o if_o it_o continue_v perfect_o cure_v they_o ☞_o hence_o it_o be_v that_o the_o use_v of_o opiate_n continue_v do_v happy_o not_o only_o palliate_v but_o perfect_o cure_v diarrheas_n dysentery_n defluxion_n catarrh_n etc._n etc._n it_o therefore_o follow_v that_o it_o be_v of_o great_a use_n 1._o to_o palliate_v moderate_a or_o cure_v all_o flux_n that_o proceed_v from_o irritation_n of_o humour_n as_o vomit_n