be_v well_o remove_v this_o prove_v how_o useful_a removal_n may_v be_v and_o how_o convenient_a in_o plague_n time_n it_o will_v be_v to_o remove_v to_o the_o wind-side_n of_o a_o town_n or_o city_n that_o be_v taint_v according_a as_o the_o wind_n change_v and_o how_o convenient_a wind_n be_v to_o convey_v away_o the_o effluviams_n and_o good_a stomachick_a cordial_n that_o be_v warm_a and_o pleasant_a to_o fortify_v the_o stomach_n and_o open_v the_o pore_n which_o all_o thing_n that_o cause_v a_o sense_n of_o pleasure_n do_v as_o wine_n spirit_n etc._n etc._n to_o which_o if_o some_o good_a preparation_n of_o opium_n be_v add_v it_o will_v be_v most_o convenient_a how_o many_o story_n have_v we_o of_o person_n well_o fill_v with_o wine_n who_o wonderful_o escape_v infection_n i_o pray_v god_n this_o hint_n may_v be_v improve_v to_o the_o preservation_n of_o mankind_n therefore_o i_o add_v that_o much_o may_v be_v in_o a_o good_a quantity_n of_o wine_n in_o this_o case_n 1._o because_o quod_fw-la intus_fw-la est_fw-la prohibet_fw-la alienum_fw-la that_o be_v what_o be_v within_o hinder_v ingress_n of_o another_o thing_n 2._o because_o the_o perspiration_n will_v be_v the_o great_a both_o upon_o the_o account_n of_o the_o great_a open_n of_o the_o pore_n by_o the_o pleasure_n of_o the_o wine_n and_o the_o great_a quantity_n of_o matter_n to_o be_v perspire_v carry_v off_o the_o venomous_a particle_n 3._o because_o the_o sensitive_a soul_n be_v thereby_o much_o comfort_v refresh_v and_o invigorate_v but_o i_o will_v have_v the_o wine_n so_o use_v as_o to_o keep_v a_o continual_a warmth_n pleasure_n and_o comfort_n at_o stomach_n which_o be_v the_o main_a cause_n of_o all_o the_o good_a i_o think_v a_o glass_n every_o hour_n after_o take_v 2_o or_o 3_o at_o first_o may_v hit_v the_o mark_n best_o the_o reason_n of_o which_o will_v appear_v hereafter_o three_o the_o stomach_n be_v exquisite_a disposition_n to_o sensation_n above_o all_o other_o organ_n and_o membrane_n appear_v by_o this_o viz._n that_o the_o offence_n of_o the_o other_o organ_n of_o sensation_n even_o by_o their_o proper_a object_n do_v often_o affect_v the_o stomach_n more_o than_o those_o very_a sense_n or_o organ_n themselves_o for_o instance_n if_o we_o smell_v a_o great_a stench_n the_o stomach_n be_v often_o more_o offend_v thereat_o than_o the_o nose_n as_o be_v manifest_a from_o the_o vomit_n faint_n and_o deliquium_n that_o be_v cause_v by_o the_o stomach_n upon_o that_o account_n so_o the_o bare_a see_v feel_v and_o taste_v of_o a_o nasty_a thing_n do_v cause_n nauseas_fw-la etc._n etc._n at_o stomach_n yea_o the_o very_a name_n of_o such_o thing_n have_v much_o offend_v it_o and_o cause_v such_o effect_n which_o may_v be_v think_v very_o strange_a consider_v that_o there_o pass_v no_o effluvias_fw-la from_o the_o sound_n of_o word_n but_o the_o reason_n will_v appear_v in_o the_o follow_a paragraph_n four_o all_o passion_n commotion_n and_o perturbation_n that_o happen_v in_o the_o body_n do_v often_o affect_v the_o stomach_n and_o sometime_o so_o grievous_o as_o to_o cause_n nauseas_fw-la vomit_n great_a anxiety_n at_o stomach_n faint_n etc._n etc._n thus_o fear_v terror_n surprise_v anger_n grief_n pain_n in_o other_o part_n etc._n etc._n cause_v some_o motion_n in_o the_o animal_n more_o than_o ordinary_a of_o which_o the_o stomach_n be_v sensible_a do_v cause_n the_o aforesaid_a disturbance_n therefore_o it_o be_v no_o wonder_n if_o the_o hear_v one_o mention_n a_o nasty_a thing_n which_o cause_v a_o abhorrence_n and_o the_o motion_n consequent_a thereunto_o shall_v as_o be_v say_v in_o the_o precedent_n paragraph_n cause_v the_o nice_a stomach_n to_o be_v offend_v it_o be_v most_o manifest_a from_o the_o premise_n that_o no_o organ_n or_o membrane_n can_v compare_v with_o the_o stomach_n as_o to_o its_o exquisite_a disposition_n for_o sensation_n it_o follow_v then_o that_o grievance_n or_o pleasure_n at_o stomach_n must_v have_v the_o great_a effect_n 1._o because_o the_o intenseness_n of_o either_o will_v be_v proportionable_a to_o the_o sensation_n 2._o because_o the_o power_n of_o the_o animal_n that_o be_v to_o defend_v it_o which_o be_v contraction_n be_v affect_v according_a to_o the_o sensation_n and_o that_o it_o be_v there_o most_o requisite_a sensible_o to_o affect_v they_o 3._o because_o what_o affect_v the_o stomach_n influence_n the_o whole_a animal_n more_o than_o the_o sensation_n of_o any_o other_o part._n 4._o because_o of_o the_o considerable_a stay_v that_o thing_n make_v at_o stomach_n to_o cause_n grievance_n or_o pleasure_n whereas_o that_o of_o pleasure_n be_v general_o very_o momentary_a in_o other_o case_n 5._o because_o be_v within_o the_o body_n we_o carry_v our_o pleasure_n or_o grievance_n with_o we_o as_o a_o vade_fw-la mecum_fw-la wherever_o we_o go_v and_o therefore_o 6._o it_o be_v a_o pleasure_n etc._n etc._n that_o can_v so_o well_o be_v take_v away_o from_o we_o as_o that_o of_o the_o tongue_n ear_n nose_n eye_n etc._n etc._n may_v by_o remove_v the_o object_n and_o therefore_o it_o remain_v with_o we_o in_o our_o very_a sleep_n as_o far_o as_o we_o be_v capable_a of_o sensation_n at_o that_o time_n cause_v pleasant_a dream_n etc._n etc._n and_o so_o agreeable_o entertain_v we_o sleep_v or_o wake_v when_o the_o pleasure_n of_o all_o the_o other_o sense_n fail_v we_o which_o will_v appear_v far_o hereafter_o the_o pleasure_n at_o stomach_n excel_v even_o that_o of_o venery_n if_o not_o in_o intenseness_n yet_o in_o several_a other_o respect_n viz._n 1._o because_o of_o its_o duration_n that_o of_o venus_n be_v momentary_a but_o that_o of_o wine_n at_o stomach_n last_v a_o good_a while_n and_o that_o of_o opium_n many_o hour_n it_o be_v therefore_o that_o the_o effect_n of_o these_o two_o be_v more_o remarkable_a and_o take_v notice_n of_o 2._o because_o that_o at_o stomach_n may_v be_v continue_v as_o long_o as_o we_o please_v by_o a_o new_a supply_n of_o wine_n opium_n cordial_n etc._n etc._n 3._o because_o it_o may_v be_v excite_v when_o and_o as_o often_o as_o we_o please_v if_o we_o have_v those_o cordial_n at_o hand_n 4._o because_o it_o be_v not_o attend_v with_o any_o expense_n of_o strength_n depression_n of_o spirit_n etc._n etc._n as_o that_o of_o venery_n but_o the_o quite_o contrary_a viz._n with_o more_o vigour_n elevation_n of_o the_o spirit_n etc._n etc._n one_o be_v by_o emission_n and_o the_o other_o upon_o admission_n of_o what_o be_v agreeable_a it_o be_v for_o the_o several_a reason_n contain_v in_o the_o premise_n that_o the_o effect_n of_o grievance_n as_o hunger_n etc._n etc._n or_o pleasure_n be_v more_o considerable_a and_o remarkable_a at_o stomach_n and_o that_o thing_n agreeable_a thereto_o have_v by_o way_n of_o eminence_n gain_v the_o name_n of_o cordial_n that_o wine_n spirit_n opium_n etc._n etc._n do_v cause_n a_o more_o permanent_a and_o notable_a gaity_n pleasantness_n good_a humour_n serenity_n promptitude_n ovation_n of_o the_o spirit_n or_o sensitive_a soul_n bravery_n courage_n magnanimity_n euphory_n or_o easy_a undergo_n of_o business_n relaxation_n with_o all_o its_o effect_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la perspiration_n etc._n etc._n which_o be_v hardly_o note_v in_o other_o short_a pleasure_n unless_o it_o be_v in_o that_o eminent_a though_o short_a one_o of_o venus_n which_o be_v a_o pleasure_n of_o the_o same_o sense_n of_o feel_v as_o that_o of_o opium_n and_o wine_n be_v therefore_o please_v the_o stomach_n be_v one_o of_o the_o great_a thing_n to_o be_v regard_v in_o the_o practice_n of_o physic_n to_o comfort_n satisfy_v or_o compose_v the_o spirit_n by_o which_o mean_n i_o have_v often_o perform_v such_o cure_n that_o neither_o i_o nor_o i_o suppose_v any_o other_o can_v otherwise_o perform_v namely_o dejection_n of_o appetite_n untowardness_n at_o stomach_n etc._n etc._n when_o all_o the_o ordinary_a and_o usual_a mean_n have_v fail_v by_o ask_v they_o what_o they_o most_o desire_a or_o long_v for_o and_o let_v they_o have_v it_o or_o if_o they_o can_v not_o tell_v of_o any_o thing_n that_o they_o long_v for_o i_o have_v mention_v to_o they_o all_o the_o relish_v thing_n that_o i_o can_v think_v of_o and_o such_o as_o be_v grateful_a to_o the_o stomach_n till_o they_o fasten_v upon_o somewhat_o that_o they_o like_v or_o fancy_v and_o then_o be_v give_v they_o it_o general_o have_v the_o desire_a success_n the_o stomach_n be_v grieve_v for_o it_o will_v concern_v we_o to_o know_v how_o because_o opium_n cause_v vomit_v etc._n etc._n general_o speak_v 1._o by_o thing_n hard_a of_o digestion_n as_o heavy_a bread_n mushroom_n rosin_n and_o such_o like_a 2._o by_o thing_n acrimonious_a or_o pungent_a as_o vomitory_n of_o asarabacca_n groundsil_n squill_n etc._n etc._n which_o abound_v with_o volatile_a salt_n 3._o by_o thing_n that_o stick_v to_o the_o stomach_n which_o
and_o alteration_n in_o a_o animal_n this_o helmont_n couch_v under_o the_o name_n of_o please_v the_o archaeus_n 3._o that_o it_o shall_v take_v away_o all_o grievance_n of_o the_o sensitive_a soul_n or_o archaeus_n because_o its_o grievance_n be_v the_o essential_a form_n of_o disease_n for_o even_o morbid_v matter_n unless_o it_o cause_v a_o grievance_n cause_v no_o more_o disease_n than_o it_o do_v in_o a_o dead_a carcase_n as_o helmont_n and_o common_a reason_n assure_v we_o therefore_o disease_n and_o grievance_n be_v only_o two_o word_n signify_v the_o same_o thing_n and_o nothing_o be_v capable_a of_o grievance_n in_o a_o animal_n as_o such_o but_o the_o sensitive_a soul_n 4._o it_o shall_v compose_v comfort_n enliven_v encourage_v and_o invigorate_v our_o sensitive_a soul_n and_o spirit_n as_o be_v the_o principle_n of_o motion_n in_o our_o animal_n nature_n in_o order_n to_o self_n preservation_n for_o nature_n or_o those_o active_a principle_n within_o we_o be_v the_o curer_n of_o disease_n and_o we_o physician_n only_a its_o minister_n to_o offer_v it_o good_a mean_n etc._n etc._n 5._o the_o principle_n of_o a_o panacea_fw-la shall_v be_v agreeable_a to_o the_o best_a noble_a most_o active_a and_o predominant_a principle_n of_o our_o body_n 6._o those_o principle_n in_o the_o panacea_fw-la shall_v be_v more_o vigorous_a than_o we_o to_o reduce_v they_o when_o deficient_a and_o exalt_v they_o when_o depress_v clog_v etc._n etc._n 7._o it_o shall_v be_v a_o general_a resolver_n of_o humour_n for_o which_o cause_n the_o liquor_n alcahe_o be_v so_o much_o extol_v for_o a_o panacea_fw-la hear_v what_o the_o great_a physician_n claudius_n de_fw-fr la_fw-fr courvee_n say_v uni_fw-la morbosae_fw-la &_o semper_fw-la preter_fw-la naturam_fw-la humorum_fw-la coagulationi_fw-la unique_fw-la eorundem_fw-la colliquationi_fw-la ovi_fw-fr perpetuo_fw-la intendit_fw-la natura_fw-la diligenter_n studeas_fw-la huius_fw-la adjuvandae_fw-la illius_fw-la corrigendae_fw-la modum_fw-la si_fw-la assecutus_fw-la fuâ—ris_fw-la habebis_fw-la in_o praxi_fw-la secretum_fw-la onmi_fw-la auro_fw-la potabili_fw-la omnique_fw-la antidoto_fw-la prestantius_fw-la denique_fw-la plus_fw-la poteris_fw-la in_o praxi_fw-la quam_fw-la si_fw-la cursus_fw-la astrorum_fw-la metallorum_fw-la vires_fw-la aut_fw-la totam_fw-la callueris_fw-la panaceam_fw-la 8._o it_o shall_v after_o such_o resolution_n of_o humour_n compose_v concentrate_v combine_v and_o unite_v the_o good_a principle_n 9_o it_o shall_v discuss_v the_o bad_a and_o useless_a part_n 10._o it_o shall_v open_v the_o pore_n to_o give_v they_o their_o exit_fw-la by_o that_o most_o universal_a natural_a plentiful_a kind_o and_o easy_a evacuation_n 11._o that_o after_o all_o it_o shall_v like_o the_o liquor_n alcahest_n remain_v very_o much_o unaltered_a in_o itself_o now_o whatsoever_o be_v endue_v with_o these_o eleven_o most_o noble_a qualification_n must_v be_v in_o the_o estimation_n of_o any_o rational_a physician_n or_o philosopher_n a_o glorious_a panacea_fw-la that_o be_v fit_v to_o take_v off_o the_o matter_n and_o form_n of_o all_o disease_n or_o grievance_n as_o far_o as_o it_o be_v in_o the_o power_n of_o a_o natural_a medicament_n or_o alterative_a so_o to_o do_v therefore_o let_v we_o see_v how_o the_o pure_a sal-volatile-oleosum_a of_o opium_n be_v furnish_v therewith_o 1._o it_o be_v so_o high_o agreeable_a and_o please_a to_o our_o most_o nice_a sensation_n at_o stomach_n which_o be_v give_v we_o for_o a_o touchstone_n watch_z and_o judge_n of_o what_o be_v agreeable_a and_o beneficial_a to_o our_o body_n that_o nothing_o in_o the_o whole_a world_n be_v so_o agreeable_a and_o please_a to_o it_o and_o therefore_o nothing_o be_v more_o agreeable_a and_o beneficial_a to_o our_o animal_n nature_n it_o will_v imply_v a_o contradiction_n that_o the_o stomach_n which_o be_v give_v we_o and_o according_o qualfy_v to_o make_v a_o true_a report_n of_o what_o be_v or_o be_v not_o agreeable_a and_o beneficial_a to_o we_o shall_v always_o though_o it_o may_v by_o accident_n possible_o give_v we_o a_o false_a report_n of_o the_o agreeableness_n of_o thing_n it_o will_v be_v more_o than_o profaneness_n to_o attribute_v such_o deceitful_a unkind_a and_o unwise_a contrivance_n to_o the_o infinite_o good_a and_o wise_a therefore_o the_o stomach_n do_v infallible_o testify_v and_o assure_v we_o that_o it_o be_v most_o agreeable_a to_o our_o nature_n see_v it_o be_v always_o so_o to_o it_o agreeableness_n and_o disagreeableness_n with_o which_o be_v appoint_v and_o ordain_v by_o god_n and_o nature_n to_o be_v the_o test_n and_o touchstone_n of_o what_o be_v agreeable_a or_o otherwise_o to_o our_o animal_n nature_n obj._n why_o then_o be_v so_o agreeable_a to_o the_o stomach_n shall_v it_o not_o create_v a_o appetite_n but_o rather_o lessen_v it_o ans._n though_o some_o may_v be_v so_o weak_a as_o to_o make_v such_o a_o objection_n because_o thing_n agreeable_a to_o the_o stomach_n be_v common_o repute_v to_o cause_v a_o appetite_n yet_o the_o matter_n due_o consider_v the_o case_n be_v quite_o contrary_a for_o appetite_n or_o hunger_n be_v a_o grievous_a sensation_n at_o stomach_n which_o can_v be_v expect_v from_o thing_n that_o gratify_v and_o please_v the_o stomach_n which_o be_v the_o adequate_a cure_n of_o a_o grievous_a sensation_n or_o hunger_n thus_o meat_n and_o drink_n as_o have_v be_v show_v cure_v a_o appetite_n grievous_a sensation_n or_o hunger_n thus_o wine_n and_o opium_n do_v by_o please_v the_o stomach_n cure_v a_o canine_a appetite_n etc._n etc._n therefore_o you_o may_v note_v by_o the_o by_o that_o all_o meat_n and_o drink_n that_o please_v the_o stomach_n and_o gratify_v its_o sense_n be_v real_o opiate_n in_o some_o degree_n cause_v good_a humour_n sleepiness_n etc._n etc._n appetite_n or_o hunger_n though_o it_o be_v a_o convenient_a call_n or_o intimation_n of_o want_n of_o supply_n and_o recruit_v be_v as_o such_o a_o consequent_a of_o defect_n and_o so_o unnatural_a though_o call_v natural_a because_o it_o be_v a_o thing_n that_o happen_v of_o course_n to_o direct_v we_o how_o to_o proportion_v thing_n to_o the_o exigence_n of_o nature_n of_o which_o there_o will_v be_v no_o need_n if_o we_o can_v otherwise_o proportion_v good_a and_o agreeable_a refection_n to_o our_o want_n thereof_o in_o short_a it_o be_v a_o disease_n which_o thing_n agreeable_a and_o please_a to_o the_o stomach_n as_o our_o panacea_fw-la must_v cure_v or_o else_o it_o will_v not_o be_v a_o panacea_fw-la and_o as_o be_v show_v nothing_o can_v be_v a_o more_o proper_a cure_n of_o grievance_n or_o displeasure_n than_o pleasure_n therefore_o what_o be_v agreeable_a to_o our_o stomach_n and_o consequent_o to_o our_o body_n must_v cure_v not_o cause_n appetite_n as_o meat_n and_o drink_n etc._n etc._n obj._n but_o it_o may_v be_v say_v that_o appetite_n argue_v a_o good_a digestion_n which_o be_v good_a for_o the_o body_n ans._n it_o do_v indeed_o argue_v a_o quick_a digestion_n and_o great_a expense_n of_o the_o recruit_n take_v in_o but_o still_o it_o be_v all_o bottom_v upon_o deficiency_n and_o digestion_n may_v be_v and_o be_v very_o often_o too_o quick_a as_o in_o the_o boulimia_fw-la or_o canine_a appetite_n nature_n delight_v in_o a_o gentle_a kind_a and_o gradual_a dissolution_n of_o the_o meat_n at_o stomach_n to_o which_o you_o will_v find_v by_o and_o by_o that_o opium_n very_o much_o conduce_v by_o its_o resolve_v quality_n 2._o nothing_o in_o nature_n be_v more_o please_v to_o the_o sensitive_a soul_n as_o appear_v by_o the_o whole_a series_n of_o our_o discourse_n and_o the_o explain_v all_o the_o phenomena_n or_o good_a effect_n of_o opium_n by_o that_o very_a pleasure_n of_o the_o sensitive_a soul_n therefore_o 3._o it_o as_o be_v manifest_o show_v do_v thereby_o take_v off_o all_o grievance_n which_o be_v the_o essential_a form_n of_o disease_n and_o the_o essential_a form_n of_o disease_n be_v take_v away_o which_o give_v they_o be_v and_o make_v they_o to_o be_v what_o they_o be_v according_a to_o the_o definition_n of_o a_o essential_a form_n the_o very_a be_v of_o disease_n must_v be_v take_v away_o therefore_o our_o sal-volatile-oleosum_a be_v a_o complete_a panacea_fw-la that_o take_v away_o the_o essence_n or_o be_v of_o disease_n in_o take_v away_o the_o grievance_n thereof_o here_o it_o may_v be_v say_v that_o the_o matter_n of_o the_o distemper_n remain_v and_o consequent_o a_o disposition_n to_o a_o relapse_n as_o soon_o as_o the_o sal-volatile-oleosum_a have_v end_v its_o operation_n but_o what_o need_v it_o end_n at_o all_o if_o you_o please_v it_o may_v be_v renew_v without_o danger_n for_o this_o be_v not_o as_o resinous_a opium_n till_o the_o matter_n be_v subdue_v thereby_o which_o it_o will_v also_o do_v as_o appear_v more_o manifest_o by_o the_o follow_a qualification_n for_o as_o have_v be_v show_v 4._o it_o compose_v comfort_n enlivens_fw-la encourage_v invigorate_n and_o cause_v a_o great_a euphory_n of_o the_o sensitive_a soul_n and_o spirit_n which_o be_v our_o natural_a active_a
that_o include_v the_o glandule_n must_v as_o in_o sleep_n which_o relax_n they_o stop_v or_o moderate_v all_o defluxion_n catarrh_n etc._n etc._n because_o they_o be_v not_o sensible_a oâ—_n the_o irritation_n of_o the_o humour_n by_o quantity_n or_o quality_n which_o irritation_n cause_v the_o defluxion_n or_o catarrh_n by_o exciting_a the_o membrane_n to_o contract_v and_o thereby_o to_o squeeze_v out_o the_o humour_n contain_v in_o the_o glandule_n four_o the_o composure_n of_o the_o spirit_n be_v procure_v main_o by_o sleep_n which_o all_o loss_n of_o spirit_n as_o be_v show_v incline_v we_o to_o so_o bleed_v which_o diminish_v the_o spirit_n compose_v their_o fury_n in_o fever_n delirium_n madness_n etc._n etc._n five_o perspiration_n be_v cause_v by_o nothing_o more_o than_o sleep_v for_o we_o perspire_v twice_o as_o much_o in_o sleep_n as_o when_o we_o watch_v as_o be_v most_o manifest_o demonstrable_a by_o the_o statick_a experiment_n of_o weigh_v people_n nor_o be_v perspiration_n ever_o so_o great_a as_o in_o deliquium_n syncopes_fw-la leipothymy_n and_o such_o like_a deadish_fw-mi case_n which_o be_v cause_v by_o diminish_v or_o disable_n of_o the_o spirit_n nay_o it_o be_v so_o in_o animal_n quite_o dead_a for_o a_o little_a time_n while_o they_o be_v hot_a as_o be_v evident_a by_o like_a statick_a demonstration_n the_o true_a cause_n of_o which_o be_v relaxation_n of_o the_o pore_n skin_n etc._n etc._n for_o want_n of_o spirit_n to_o contract_n and_o constringe_v they_o as_o shall_v be_v full_o prove_v hereafter_o by_o god_n help_n these_o thing_n be_v doubtless_o the_o occasion_n of_o that_o hypothesis_n of_o diminish_v or_o disable_n the_o spirit_n by_o opium_n but_o how_o likely_a be_v they_o to_o err_v by_o establish_v it_o without_o any_o consideration_n of_o its_o enliven_a encourage_v and_o brisk_a effect_n as_o ovation_n of_o the_o spirit_n gaity_n bravery_n magnanimity_n euphory_n promptitude_n to_o venery_n etc._n etc._n which_o can_v never_o be_v solve_v by_o diminution_n or_o disability_n of_o the_o spirit_n till_o depression_n and_o elevation_n thereof_o be_v reconcilable_a and_o consistent_a at_o the_o same_o time_n in_o the_o same_o subject_n which_o can_v never_o be_v till_o disable_n and_o not_o disable_n be_v the_o same_o thing_n have_v not_o we_o then_o good_a reason_n to_o suspect_v that_o general_a foundation_n of_o diminish_v or_o disable_n the_o spirit_n by_o opium_n which_o be_v lay_v by_o such_o as_o never_o consider_v any_o thing_n of_o its_o generous_a and_o sprightly_a effect_n which_o as_o have_v be_v show_v be_v its_o constant_a and_o therefore_o most_o proper_a and_o genuine_a effect_n who_o can_v doubt_v then_o but_o they_o must_v err_v in_o lay_v a_o foundation_n quite_o contrary_a to_o the_o very_a property_n of_o opium_n 5._o i_o observe_v that_o all_o our_o modern_a author_n and_o physician_n receive_v the_o knowledge_n of_o opium_n its_o effect_n and_o uses_n from_o those_o ancient_n do_v use_v it_o only_o for_o the_o same_o end_n and_o purpose_v as_o they_o do_v and_o that_o our_o modern_a author_n live_v in_o these_o western_a part_n of_o the_o world_n very_o remote_a from_o the_o eastern_a country_n where_o it_o be_v use_v common_o and_o in_o large_a dose_n by_o people_n in_o health_n in_o the_o daytime_n to_o enliven_v invigorate_a and_o encourage_v they_o and_o cause_v the_o brave_a generous_a and_o magnanimous_a effect_n aforemention_v viz._n courage_n euphory_n etc._n etc._n and_o find_v no_o physician_n that_o go_v before_o they_o to_o mention_v these_o noble_a cordial_a and_o glorious_a effect_n and_o if_o they_o do_v at_o any_o time_n slight_o touch_v they_o to_o do_v it_o with_o all_o imaginable_a disregard_n neglect_v and_o contempt_n as_o if_o there_o be_v no_o heed_n to_o be_v take_v of_o they_o but_o as_o idle_a tale_n and_o improbable_a story_n be_v contrary_a and_o utter_o as_o they_o think_v inconsistent_a and_o irreconcilable_a with_o the_o daily_a and_o most_o notorious_a effect_n of_o opium_n observe_v among_o we_o and_o to_o the_o universal_a opinion_n of_o all_o author_n who_o state_v opium_n to_o be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n which_o can_v not_o produce_v as_o they_o conclude_v such_o contradictory_n and_o therefore_o to_o they_o utter_o incredible_a effect_n and_o fabulons_a flam_n arise_v as_o they_o fancy_v from_o some_o silly_a error_n as_o want_v of_o due_a observation_n in_o traveller_n mistake_a discourse_n and_o the_o like_a so_o that_o as_o the_o say_n be_v they_o let_v they_o in_o at_o one_o ear_n and_o out_o at_o the_o other_o there_o be_v no_o such_o contrary_a effect_n of_o any_o one_o thing_n to_o be_v observe_v in_o the_o whole_a creation_n and_o they_o be_v well_o assure_v of_o the_o other_o effect_n by_o daily_a experience_n and_o have_v never_o observe_v those_o lively_a effect_n for_o the_o several_a plain_a reason_n that_o you_o will_v meet_v in_o the_o follow_a paragraph_n have_v no_o cause_n to_o alter_v their_o opinion_n when_o all_o thing_n seem_v to_o they_o to_o make_v for_o their_o hypothesis_n for_o want_v of_o a_o notion_n of_o those_o brisk_a effect_n 6._o i_o observe_v that_o those_o brisk_a effect_n of_o opium_n be_v not_o take_v notice_n of_o by_o our_o physician_n nor_o indeed_o all_o thing_n consider_v do_v i_o well_o see_v how_o they_o shall_v without_o get_v out_o of_o the_o common_a road_n of_o observe_v which_o be_v sometime_o as_o i_o have_v find_v very_o useful_a upon_o such_o occasion_n for_o first_o opium_n be_v seldom_o if_o ever_o give_v in_o these_o western_a nation_n but_o to_o sick_a people_n as_o the_o ancient_n do_v who_o be_v utter_o incapable_a of_o those_o brisk_a effect_n or_o at_o least_o to_o any_o remarkable_a degree_n that_o may_v call_v for_o a_o particular_a or_o special_a advertency_n or_o attention_n without_o which_o they_o pass_v off_o as_o they_o come_v without_o any_o reflection_n thereupon_o and_o so_o signify_v nothing_o as_o if_o they_o have_v never_o happen_v second_o we_o as_o the_o ancient_n do_v general_o give_v opium_n when_o people_n be_v go_v to_o bed_n by_o which_o mean_v all_o opportunity_n of_o observation_n be_v lose_v because_o darkness_n and_o be_v alone_o hide_v or_o hinder_v the_o show_v of_o any_o such_o effect_n and_o the_o physician_n who_o only_a business_n it_o be_v to_o be_v more_o curious_a in_o such_o matter_n be_v go_v to_o his_o own_o rest_n though_o if_o he_o be_v present_a not_o likely_a to_o take_v any_o observation_n of_o such_o matter_n whereof_o he_o have_v least_o thought_n or_o belief_n as_o be_v in_o his_o opinion_n contrary_a to_o all_o reason_n sense_n experience_n and_o the_o opinion_n of_o all_o author_n of_o the_o stupefactive_a quality_n of_o opium_n in_o which_o they_o all_o agree_v three_o opium_n be_v as_o be_v say_v give_v in_o these_o country_n to_o cause_n sleep_n or_o such_o effect_n to_o which_o sleep_n conduce_v as_o compose_v the_o spirit_n cause_v indolence_n stop_v flux_n and_o promote_a perspiration_n and_o therefore_o always_o give_v with_o all_o careful_a direction_n and_o injunction_n that_o may_v conduce_v to_o that_o end_n as_o go_v to_o bed_n lie_v still_o put_v out_o light_n keep_v silence_n etc._n etc._n which_o concur_v with_o the_o opium_n cause_n sleep_n which_o be_v utter_o inconsistent_a with_o show_v any_o of_o those_o lively_a effect_n that_o belong_v only_o to_o a_o wake_a person_n to_o do_v so_o that_o all_o opportunity_n of_o observation_n be_v utter_o preclude_v now_o all_o the_o premise_n consider_v it_o can_v be_v conceive_v that_o such_o as_o set_v their_o mind_n upon_o contrary_a effect_n and_o expect_v no_o other_o much_o less_o contrary_a one_o against_o which_o also_o they_o be_v high_o prejudice_v by_o their_o reason_n experience_n and_o read_v shall_v observe_v such_o brisk_a effect_n if_o they_o do_v happen_v and_o how_o can_v a_o brisk_a humour_n courage_n easy_a undergo_n of_o labour_n promptitude_n to_o venus_n etc._n etc._n be_v observe_v in_o sick_a and_o infirm_a people_n lie_v in_o bed_n alone_z and_o in_o the_o dark_a or_o which_o render_v it_o utter_o impossible_a while_o they_o be_v asleep_a and_o the_o thing_n itself_o disbelieved_a and_o esteem_v contrary_a to_o common_a sense_n and_o the_o universal_a sentiment_n of_o the_o learned_a and_o all_o other_o therefore_o 7._o if_o after_o all_o any_o such_o brisk_a effect_n do_v ever_o happen_v it_o must_v be_v either_o not_o regard_v or_o if_o observe_v which_o be_v no_o way_n likely_a as_o be_v show_v you_o may_v be_v sure_a for_o the_o many_o plain_a reason_n and_o cause_n aforesaid_a that_o it_o be_v not_o impute_v to_o stupify_a opium_n as_o all_o esteem_v it_o but_o to_o any_o other_o cause_n or_o accident_n rather_o than_o to_o a_o thing_n well_o know_v to_o have_v quite_o contrary_a effect_n for_o instance_n if_o the_o sick_a person_n happen_v to_o be_v
watch_n and_o sentinel_n to_o discover_v and_o give_v notice_n of_o what_o be_v or_o be_v not_o good_a and_o agreeable_a to_o our_o animal_n nature_n that_o upon_o notice_n of_o what_o be_v good_a and_o agreeable_a pleasure_n comfort_n satisfaction_n etc._n etc._n be_v conceive_v otherwise_o displeasure_n discomfort_n and_o dissatisfaction_n what_o diminish_v or_o disable_v our_o spirit_n do_v we_o the_o great_a evil_n that_o can_v be_v and_o consequent_o sensation_n will_v according_a to_o its_o office_n give_v we_o such_o notice_n thereof_o as_o will_v cause_v displeasure_n etc._n etc._n otherwise_o these_o sentinel_n that_o god_n and_o nature_n have_v appoint_v for_o faithful_a notice_n will_v instead_o of_o trusty_a service_n which_o be_v the_o end_n they_o be_v make_v for_o deceive_v we_o and_o consequent_o do_v we_o mischief_n rather_o than_o good_a which_o be_v very_o profane_a if_o not_o blasphemous_a to_o assert_v as_o be_v high_o abusive_a of_o god_n goodness_n and_o wisdom_n to_o make_v thing_n in_o nature_n that_o will_v not_o only_o not_o answer_n but_o act_n quite_o contrary_a to_o their_o end_n it_o follow_v then_o that_o what_o cause_v such_o a_o mighty_a agreeable_a and_o pleasant_a sensation_n at_o stomach_n which_o be_v the_o great_a and_o most_o accurate_a judge_n of_o what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n can_v be_v destructive_a or_o disable_n of_o its_o spirit_n which_o be_v the_o most_o excellent_a and_o useful_a thing_n that_o belong_v thereto_o therefore_o opium_n which_o so_o mighty_o recommend_v itself_o to_o please_v and_o comfort_v the_o great_a judge_n that_o god_n have_v give_v to_o a_o sensible_a creature_n to_o discern_v what_o be_v good_a and_o evil_a for_o it_o can_v diminish_v or_o disable_v our_o spirit_n one_o may_v say_v what_o i_o dare_v not_o that_o the_o sensation_n at_o stomach_n may_v deceive_v we_o we_o may_v deceive_v ourselves_o and_o say_v so_o when_o that_o which_o please_v the_o stomach_n do_v not_o please_v our_o pervert_v imagination_n which_o make_v no_o argument_n let_v we_o therefore_o consider_v thing_n where_o there_o be_v no_o such_o vain_a imagination_n to_o contradict_v the_o good_a end_n of_o nature_n if_o the_o stomach_n and_o sense_n in_o a_o brute_n or_o mere_a animal_n which_o have_v no_o other_o mean_n to_o judge_n of_o what_o be_v good_a or_o evil_n for_o it_o shall_v not_o judge_v aright_o all_o the_o animal_n in_o the_o whole_a world_n will_v soon_o perish_v it_o be_v the_o vain_a opinion_n of_o man_n that_o persuade_v they_o that_o thing_n be_v cold_a when_o hot_a etc._n etc._n as_o in_o the_o case_n of_o opium_n when_o the_o sense_n true_o inform_v that_o it_o be_v hot_a if_o you_o will_v stand_v to_o your_o imagination_n and_o supposition_n for_o such_o all_o must_v be_v without_o the_o information_n of_o sense_n against_o the_o dictate_v of_o sensation_n you_o must_v inevitable_o err_v but_o one_o may_v say_v be_v the_o sense_n at_o stomach_n such_o a_o infallible_a guide_n always_o i_o believe_v it_o will_v be_v very_o hard_a to_o give_v many_o instance_n to_o the_o contrary_a and_o prove_v it_o well_o however_o if_o we_o do_v or_o may_v allow_v something_o of_o this_o kind_a to_o a_o pervert_v stomach_n at_o certain_a time_n to_o avoid_v a_o squabble_n about_o it_o it_o be_v never_o to_o be_v allow_v that_o all_o the_o stomach_n in_o the_o whole_a world_n shall_v be_v please_v with_o one_o and_o the_o same_o thing_n at_o all_o time_n and_o yet_o that_o this_o thing_n shall_v be_v so_o high_o pernicious_a to_o the_o animal_n as_o to_o diminish_v or_o disable_v its_o spirit_n then_o indeed_o it_o will_v follow_v that_o the_o most_o exquisite_a sense_n at_o stomach_n to_o discern_v what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n be_v absolute_o in_o vain_a which_o no_o man_n of_o reason_n that_o have_v any_o apprehension_n of_o the_o wisdom_n of_o god_n and_o nature_n can_v assert_v 3._o what_o be_v more_o notorious_a than_o that_o pleasure_n or_o be_v please_v raise_v and_o displeasure_n or_o be_v grieve_v depress_n the_o spirit_n be_v not_o all_o people_n pleasant_a gay_a and_o good_a humour_a brisk_a prompt_a etc._n etc._n when_o please_v do_v not_o man_n travel_v or_o labour_n with_o more_o ease_n in_o pleasant_a company_n etc._n etc._n but_o of_o these_o matter_n and_o the_o reason_n thereof_o more_o in_o the_o follow_a chapter_n 4._o how_o can_v opium_n that_o revive_v people_n when_o they_o be_v so_o dispirited_a that_o they_o be_v even_o almost_o die_v as_o when_o opium_n be_v want_v by_o such_o as_o use_v to_o take_v it_o in_o deliquiâ—ms_n and_o agony_n from_o paiâ—_n etc._n etc._n diminish_v or_o disable_v the_o spirit_n it_o be_v plain_a contradiction_n to_o say_v that_o it_o shall_v next_o to_o opium_n nothing_o revive_v people_n in_o such_o case_n better_o than_o wine_n and_o those_o thing_n that_o produce_v the_o same_o or_o like_a effect_n have_v like_o nature_n and_o who_o can_v say_v that_o wine_n that_o be_v make_v to_o glad_a the_o heart_n of_o man_n diminish_v or_o disable_v the_o spirit_n or_o that_o opium_n which_o produce_v all_o the_o sprightly_a enliven_a and_o encourage_v effect_n of_o generous_a wine_n in_o a_o more_o eminent_a manner_n than_o wine_n and_o in_o the_o 10000th_o part_n of_o its_o quantity_n and_o for_o a_o long_a time_n than_o wine_n cause_v they_o shall_v diminish_v or_o disable_v the_o spirit_n for_o instance_n wine_n and_o opium_n in_o a_o due_a quantity_n but_o opium_n in_o a_o far_o less_o quantity_n as_o be_v say_v cause_v a_o pleasant_a gay_a and_o good_a humour_n courage_n bravery_n magnanimity_n promptitude_n in_o business_n expediteness_n in_o management_n serenity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n fatigue_n etc._n etc._n both_o take_v away_o sadness_n grief_n melancholy_n fear_v depression_n of_o spirit_n etc._n etc._n both_o cause_n promptitude_n to_o venery_n sine_fw-la cerere_fw-la &_o baccho_fw-la friget_fw-la venus_n so_o wine_n and_o opium_n prevent_v and_o cure_v cold_a open_v the_o pore_n promote_v perspiration_n and_o sweat_n especial_o the_o follow_a morning_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v of_o opium_n and_o be_v notorious_a as_o to_o wine_n both_o cause_n sleep_n and_o take_v away_o the_o sense_n of_o pain_n and_o require_v a_o great_a dose_n than_o ordinary_a in_o proportion_n to_o the_o pain_n both_o take_v off_o shivering_n from_o fear_n cold_a or_o ague_n fit_n and_o cause_n mirth_n contentation_n and_o acquiescence_n dryness_n of_o the_o mouth_n thirst_v a_o sense_n of_o heat_n within_o we_o a_o dream_v condition_n pleasant_a dream_n if_o the_o quantity_n of_o wine_n be_v not_o grievous_a by_o its_o heat_n load_n etc._n etc._n nocturnal_a pollution_n and_o in_o some_o constitution_n both_o cause_n vigilancy_n but_o wine_n and_o opium_n cause_v that_o more_o rare_o than_o sleep_n both_o stop_n and_o cause_n vomit_v if_o they_o stay_v too_o long_o at_o stomach_n both_o moderate_a hunger_n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d and_o be_v good_a in_o a_o canine_a appetite_n both_o cause_n swim_v in_o the_o head_n etc._n etc._n so_o both_o in_o a_o excessive_a do_v do_v cause_n at_o first_o mirth_n and_o afterward_o a_o kind_n of_o drunken_a soper_n in_o some_o in_o other_o fury_n or_o madness_n sardonick_a laughter_n and_o weight_n at_o stomach_n vomit_n hiccough_n great_a heat_n at_o stomach_n debility_n and_o laxity_n of_o all_o part_n falter_v of_o the_o tongue_n scotomy_n and_o darkness_n of_o the_o eye_n vertigo_n laxity_n of_o the_o cornea_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la deadness_n of_o the_o eye_n to_o the_o view_n loss_n of_o memory_n venereal_a fury_n a_o high_a colour_n profuse_a sweat_v purge_v sometime_o alienation_n of_o the_o mind_n loss_n of_o memory_n and_o last_o great_a or_o lesser_a effect_n according_a to_o the_o do_v constitution_n etc._n etc._n so_o a_o long_a and_o lavish_a use_n of_o both_o cause_n a_o dull_a and_o moapish_a disposition_n dropsy_n fall_v of_o humour_n upon_o weaken_v part_n a_o sleepy_a disposition_n want_v of_o appetite_n weakness_n of_o digestion_n aptitude_n to_o sterility_n and_o abortion_n early_a decrepiteness_n stoop_v in_o the_o back_n tremble_v of_o the_o hand_n weakness_n of_o memory_n shortness_n of_o life_n difficulty_n and_o danger_n in_o sudden_o leave_v they_o off_o revive_v such_o as_o sink_v for_o want_n of_o either_o and_o supply_v the_o want_n of_o each_o other_o how_o can_v any_o have_v the_o face_n to_o say_v that_o a_o thing_n which_o agree_v so_o with_o generous_a wine_n in_o effect_n can_v be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n the_o mischief_n of_o excessive_a dose_n and_o lavish_a use_n of_o either_o be_v no_o argument_n against_o their_o inspirit_a nature_n if_o it_o be_v than_o wine_n be_v no_o cordial_n though_o make_v to_o glad_a the_o heart_n
preparatory_a discourse_n about_o sensation_n pleasure_n etc._n etc._n in_o the_o follow_a chapter_n you_o may_v sometime_o wonder_v what_o i_o will_v be_v at_o because_o you_o may_v not_o perceive_v the_o drift_n yet_o do_v they_o require_v your_o attention_n as_o be_v the_o foundation_n of_o all_o that_o be_v to_o follow_v which_o you_o will_v plain_o perceive_v afterward_o when_o i_o hope_v you_o will_v have_v good_a satisfaction_n for_o your_o patient_a and_o attentive_a perusal_n of_o the_o two_o follow_a chapter_n chap_n xiii_o of_o the_o oeconomy_n of_o sensation_n as_o far_o at_o least_o as_o it_o concern_v our_o present_a purpose_n when_o i_o have_v write_v this_o tract_n thus_o far_o i_o judge_v it_o best_o first_o to_o publish_v that_o of_o animal_n mechanism_n because_o it_o contain_v those_o principle_n that_o will_v explain_v the_o matter_n of_o opium_n therefore_o lay_v this_o aside_o i_o apply_v myself_o to_o that_o but_o a_o new_a art_n right_o to_o spell_n write_v and_o sweeten_v all_o language_n that_o i_o since_o call_v phonography_n come_v into_o my_o mind_n and_o think_v it_o may_v be_v very_o useful_a and_o likely_a to_o lie_v for_o ever_o in_o darkness_n as_o it_o have_v always_o be_v unless_o i_o undertake_v the_o drudgery_n i_o set_v myself_o to_o it_o which_o take_v up_o more_o time_n than_o i_o imagine_v have_v to_o this_o day_n hinder_v the_o finish_n of_o that_o tract_n of_o animal_n mechanism_n which_o i_o now_o much_o want_n as_o be_v intimate_v therefore_o because_o i_o resolve_v to_o publish_v this_o that_o be_v so_o long_o since_o promise_v i_o be_o now_o force_v for_o want_v of_o that_o book_n to_o premise_v here_o some_o thing_n concern_v the_o oeconomy_n of_o sensation_n and_o the_o nature_n of_o sensitive_a pleasure_n in_o order_n to_o explicate_v the_o effect_n of_o opium_n which_o may_v have_v be_v spare_v if_o that_o of_o animal_n mechanism_n have_v be_v publish_v consider_v that_o opium_n must_v as_o be_v show_v operate_v by_o please_v the_o sense_n of_o feel_v it_o will_v be_v requisite_a to_o consider_v 1._o the_o oeconomy_n of_o sensation_n as_o far_o as_o it_o concern_v the_o present_a purpose_n for_o which_o this_o chapter_n be_v design_v 2._o the_o nature_n of_o sensitive_a pleasure_n and_o its_o effect_n upon_o the_o sensitive_a soul_n and_o body_n which_o be_v to_o be_v the_o subject_a of_o the_o follow_a chapter_n five_o thing_n main_o concern_v the_o oeconomy_n of_o sensation_n 1._o the_o object_n 2._o the_o external_a medium_fw-la 3._o the_o organ_n of_o sensation_n 4._o the_o animal_n spirit_n or_o internal_a medium_fw-la 5._o the_o sensitive_a soul_n 1._o the_o object_n be_v the_o thing_n perceive_v by_o any_o of_o the_o sense_n as_o light_n by_o the_o eye_n sound_v or_o tremulous_a motion_n of_o the_o air_n by_o the_o ear_n odour_n by_o the_o nose_n taste_n by_o the_o tongue_n opium_n by_o the_o feel_n or_o as_o helmont_n call_v it_o the_o gustus_n or_o taste_n at_o stomach_n 2._o the_o external_n medium_fw-la of_o sensation_n be_v that_o which_o receive_v impression_n from_o the_o object_n and_o convey_v they_o to_o the_o organ_n of_o sensation_n thus_o the_o air_n convey_v sound_a or_o tremulous_a motion_n to_o the_o ear_n light_n to_o the_o eye_n and_o odour_n to_o the_o nose_n 3._o the_o organ_n be_v the_o part_n of_o the_o body_n that_o god_n have_v frame_v to_o receive_v those_o impression_n and_o communicate_v they_o to_o the_o animal_n spirit_n or_o internal_a medium_fw-la thus_o the_o eye_n be_v the_o organ_n to_o receive_v the_o impression_n of_o light_n the_o ear_n that_o of_o sound_n etc._n etc._n and_o the_o membrane_n in_o all_o part_n of_o the_o body_n be_v the_o organ_n that_o receive_v impression_n from_o object_n in_o the_o case_n of_o feel_v which_o be_v our_o main_n concern_v 4._o the_o internal_a medium_fw-la be_v the_o animal_n spirit_n that_o receive_v the_o impression_n from_o the_o organ_n and_o convey_v they_o to_o the_o sensitive_a soul_n 5._o the_o sensitive_a soul_n which_o perceive_v those_o impression_n convey_v to_o he_o by_o the_o animal_n spirit_n which_o perception_n be_v sensation_n i._o the_o part_n office_n or_o business_n of_o the_o object_n in_o the_o matter_n of_o sensation_n be_v to_o make_v a_o sufficient_a impression_n either_o upon_o the_o external_n medium_fw-la or_o air_n as_o in_o the_o case_n of_o hear_v etc._n etc._n or_o immediate_o upon_o the_o organ_n or_o membrane_n as_o in_o feel_v etc._n etc._n therefore_o if_o there_o be_v no_o impression_n of_o light_n sound_z or_o tremulous_a motion_n odour_n relish_v particle_n etc._n etc._n there_o can_v be_v no_o perception_n or_o if_o the_o inpression_n thereof_o be_v weak_a and_o faint_a the_o perception_n or_o sensation_n must_v be_v according_o or_o if_o it_o be_v so_o inconsiderable_a that_o it_o can_v at_o all_o affect_v the_o sensitive_a soul_n then_o be_v there_o no_o perception_n thereof_o for_o 1._o sensitive_a perception_n be_v not_o infinite_a because_o there_o be_v degree_n of_o light_n sound_z etc._n etc._n that_o can_v be_v perceive_v though_o they_o must_v be_v very_o small_a and_o inconsiderable_a thus_o the_o light_n of_o a_o candle_n at_o so_o great_a a_o distance_n that_o it_o can_v hardly_o be_v perceive_v be_v some_o degree_n of_o light_n and_o make_v its_o reflection_n proportionable_o from_o a_o wall_n tree_n etc._n etc._n yet_o can_v that_o reflect_v light_n from_o the_o wall_n or_o tree_n be_v perceive_v so_o the_o small_a thing_n can_v be_v perceive_v yet_o god_n have_v in_o his_o wisdom_n and_o goodness_n so_o order_v it_o that_o 2._o sensitive_a perception_n be_v of_o excessive_o small_a thing_n thus_o the_o sound_n of_o a_o pin_n head_n fall_v into_o a_o brass_n cauldron_n be_v hear_v at_o some_o distance_n the_o hundred_o part_n of_o a_o grain_n of_o very_a hot_a and_o bite_a thing_n be_v sensible_o taste_v the_o thousand_o part_n of_o a_o grain_n of_o ambergrise_n musk_n etc._n etc._n very_o sensible_o smell_v the_o light_n of_o a_o exceed_a small_a spark_n strike_v out_o between_o steel_n and_o flint_n be_v perceive_v at_o a_o great_a distance_n and_o light_n in_o general_n consist_v of_o such_o tenuious_n particle_n if_o material_a that_o none_o ever_o can_v take_v any_o estimate_n of_o their_o bulk_n so_o the_o feel_n at_o stomach_n take_v very_o eminent_a and_o remarkable_a notice_n of_o as_o be_v say_v the_o vomitery_a particle_n of_o crocus_n metallorum_fw-la or_o regulus_n of_o antimony_n which_o be_v so_o small_a that_o a_o thousand_o vomit_n thereof_o do_v not_o sensible_o diminish_v the_o crocus_n or_o regulus_n either_o in_o weight_n or_o bulk_n therefore_o it_o be_v no_o wonder_n if_o a_o grain_n of_o opium_n shall_v affect_v the_o feel_v so_o sensible_o as_o it_o do_v especial_o at_o stomach_n though_o it_o can_v make_v any_o considerable_a alteration_n of_o the_o blood_n 3._o that_o whatever_o affect_v or_o make_v impression_n upon_o the_o organ_n of_o sensation_n be_v in_o the_o same_o moment_n perceive_v by_o the_o sensitive_a soul_n so_o that_o it_o be_v no_o wonder_n that_o a_o grain_n of_o opium_n operate_v in_o so_o short_a a_o time_n that_o be_v as_o soon_o as_o a_o tincture_n thereof_o insinuate_v itself_o through_o the_o crusta_fw-la carnosa_fw-la to_o the_o sensile_a coat_n of_o the_o stomach_n whereas_o it_o must_v take_v a_o very_a long_a time_n if_o it_o operate_v as_o a_o alterative_a of_o the_o blood_n now_o note_v 1._o that_o there_o be_v no_o way_n for_o any_o thing_n to_o operate_v upon_o the_o sensitive_a soul_n in_o so_o small_a a_o quanty_n as_o opium_n operate_v or_o in_o so_o short_a a_o time_n as_o by_o affect_v the_o most_o exquisite_o dispose_v membrane_n at_o stomach_n 2._o that_o the_o speedy_a way_n that_o god_n have_v contrive_v for_o our_o refreshment_n comfort_n raise_v of_o our_o depress_a spirit_n upon_o any_o sudden_a occasion_n as_o in_o delinquium_n faint_n syncopes_fw-la leipothymy_n etc._n etc._n be_v by_o the_o sense_n especial_o that_o most_o exquisite_a sensation_n at_o stomach_n because_o refreshment_n by_o nourishment_n and_o alteration_n can_v be_v perform_v but_o in_o a_o long_a time_n wherein_o we_o may_v in_o many_o case_n perish_v before_o we_o can_v be_v relieve_v thereby_o thus_o a_o please_a and_o therefore_o comfortable_a odour_n excite_v the_o spirit_n in_o a_o moment_n the_o sight_n of_o a_o belove_a mistress_n or_o dear_a friend_n raise_v we_o immediate_o when_o we_o be_v most_o cast_v down_o as_o do_v also_o sweet_a melody_n and_o a_o aggreeable_a or_o pleasant_a sensation_n at_o stomach_n as_o of_o wine_n cordial_n hot_a spirit_n etc._n etc._n i_o hope_v none_o will_v say_v that_o music_n the_o sight_n of_o a_o bag_n of_o money_n etc._n etc._n send_v effâ—uvia's_n for_o that_o end_n yet_o be_v great_a comforter_n ii_o the_o part_n office_n or_o business_n of_o the_o external_n medium_fw-la in_o the_o
which_o have_v be_v in_o some_o measure_n enumerate_v in_o the_o case_n of_o natural_a sleep_n in_o this_o chapter_n viz._n satisfaction_n composure_n of_o fret_n and_o commotion_n as_o of_o diary_n fever_n hysterick_a fit_n etc._n etc._n perspiration_n quiet_v of_o vomit_n hiccough_n etc._n etc._n lessen_v of_o feel_v and_o consequent_o a_o stop_n and_o moderation_n of_o all_o flux_n that_o depend_v upon_o irritation_n of_o humour_n as_o diarrhea_n dysentery_n catarrh_n vomit_n dryness_n of_o the_o mouth_n as_o in_o sleep_n for_o want_v of_o the_o contraction_n to_o squeeze_v the_o spital_n out_o of_o the_o glandule_n into_o the_o mouth_n nocturnal_a pollution_n etc._n etc._n but_o of_o the_o nature_n and_o effect_n of_o pleasure_n you_o will_v find_v more_o in_o the_o next_o chapter_n beside_o the_o vigilative_a and_o defensive_a contraction_n which_o seem_v to_o be_v thing_n of_o course_n upon_o wake_v and_o grievance_n the_o sensitive_a soul_n have_v a_o contraction_n at_o will_n as_o that_o of_o the_o pupilla_fw-la when_o a_o animal_n be_v intent_n upon_o see_v of_o the_o tympan_n when_o intent_n upon_o hear_v of_o the_o musole_n of_o the_o leg_n when_o intent_n upon_o walk_v and_o so_o of_o all_o the_o muscle_n of_o the_o body_n which_o i_o call_v intentive_a contraction_n that_o he_o can_v perform_v either_o along_o with_o or_o without_o the_o other_o contraction_n or_o without_o any_o great_a degree_n thereof_o as_o when_o one_o be_v considerable_o relax_v with_o the_o pleasure_n of_o wine_n very_o good_a news_n etc._n etc._n nay_o sometime_o even_o in_o sleep_n as_o be_v manifest_a by_o the_o noctamâ—uli_n or_o such_o as_o walk_v in_o their_o sleep_n and_o such_o as_o speak_v strike_v etc._n etc._n while_o asleep_a and_o as_o the_o defensive_a contraction_n do_v all_o it_o can_v in_o our_o defence_n without_o the_o direction_n of_o the_o will_n as_o in_o vomit_v sneeze_n purge_v etc._n etc._n upon_o sensible_a irritation_n so_o this_o intentive_a contraction_n do_v all_o it_o can_v to_o the_o same_o purpose_n by_o the_o direction_n and_o dictate_v thereof_o note_v that_o insensile_a grow_a thing_n that_o do_v not_o move_v as_o tree_n etc._n etc._n have_v none_o of_o these_o contraction_n but_o what_o happen_v by_o cold_a and_o compression_n of_o the_o atmosphere_n which_o be_v sufficient_a it_o seem_v for_o nutrition_n but_o not_o for_o sense_n and_o motion_n it_o follow_v that_o in_o complete_a syncopes_fw-la when_o the_o sensitive_a soul_n give_v over_o all_o contraction_n that_o we_o be_v much_o in_o the_o state_n of_o a_o plant._n all_o those_o three_o contraction_n viz._n the_o vigilative_a defensive_a and_o intentive_a do_v because_o they_o promote_v motion_n and_o cause_v it_o more_o or_o less_o as_o you_o find_v the_o vigilative_a cause_n much_o more_o of_o it_o than_o sleep_v and_o the_o defensive_a more_o than_o that_o etc._n etc._n spend_v the_o spirit_n cause_n weariness_n etc._n etc._n the_o vigilative_a contraction_n do_v of_o itself_o without_o any_o considerable_a grievance_n or_o labour_n that_o be_v without_o the_o denfensive_a or_o intentive_a contraction_n tire_v the_o sensitive_a soul_n in_o about_o 16_o hour_n hence_o it_o be_v that_o the_o idle_v person_n that_o be_v most_o free_a from_o care_n trouble_v or_o pain_n can_v well_o hold_v out_o without_o the_o recruit_v of_o sleep_n any_o long_o the_o defensive_a contraction_n or_o that_o of_o grievance_n be_v add_v to_o the_o vigilative_a contraction_n the_o spirit_n be_v fast_o spend_v and_o the_o person_n tire_v proportionable_o soon_o according_a as_o the_o grievance_n be_v more_o or_o less_o and_o consequent_o the_o endeavour_n of_o the_o sensitive_a soul_n to_o be_v rid_v thereof_o to_o both_o which_o contraction_n viz._n the_o vigilative_a and_o defensive_a if_o you_o add_v the_o intentive_a or_o labour_n then_o be_v you_o soon_o and_o more_o tire_v than_o by_o only_a those_o two_o former_a contraction_n for_o this_o last_o case_n be_v labour_v in_o pain_n or_o under_o a_o grievance_n which_o notorious_o tire_v man_n or_o beast_n soon_o than_o ordinary_a the_o direct_a contrary_n to_o which_o be_v sleep_v sound_o and_o sweet_o without_o trouble_n pain_n or_o dream_n for_o a_o dream_a condition_n have_v too_o much_o of_o the_o vigilative_a contraction_n in_o it_o to_o be_v pure_a relaxation_n and_o recruit_v now_o according_a as_o these_o contraction_n be_v or_o be_v not_o add_v one_o to_o another_o we_o be_v soon_o or_o late_a before_o we_o be_v tire_v speak_v general_o and_o not_o consider_v custom_n and_o habit_n which_o concern_v we_o not_o you_o see_v that_o all_o the_o three_o contraction_n conour_v do_v soon_o and_o sad_o tire_v we_o that_o no_o two_o of_o they_o tire_v we_o as_o much_o as_o the_o three_o together_o that_o iâ—_n neither_o the_o vigilative_a and_o defensive_a without_o the_o intentive_a nor_o the_o vigilative_a and_o intentive_a without_o the_o defensive_a and_o the_o vigilative_a alone_o lest_o of_o all_o yet_o allowance_n must_v be_v make_v for_o the_o intenseness_n of_o the_o defensive_a and_o intentive_a for_o either_o of_o these_o two_o be_v very_a intense_a may_v tire_v as_o much_o as_o both_o in_o a_o moderate_a degree_n thus_o a_o man_n may_v be_v tire_v with_o violent_a labour_n in_o four_o hour_n though_o not_o in_o pain_n as_o much_o as_o one_o that_o moderate_o labour_v in_o some_o small_a pain_n for_o the_o same_o time_n observe_v that_o we_o recruit_v in_o eight_o hour_n general_o speak_v as_o much_o by_o relaxation_n in_o sleep_n as_o we_o spend_v by_o vigilative_a contraction_n in_o sixteen_o i_o take_v the_o reason_n of_o that_o to_o be_v that_o relaxation_n widen_v all_o the_o passage_n of_o the_o body_n the_o nutriment_n be_v admit_v into_o they_o more_o full_o and_o free_o as_o the_o blood_n be_v into_o the_o skin_n in_o sleep_n and_o all_o relaxation_n which_o cause_n a_o efflorescence_n thereof_o in_o those_o case_n hence_o it_o be_v that_o we_o be_v so_o much_o recruit_v and_o nourish_v in_o sleep_n that_o child_n grow_v more_o than_o other_o proportionable_o that_o relaxer_n cause_v the_o breast_n etc._n etc._n to_o grow_v note_v what_o a_o mighty_a restaurative_a relaxation_n be_v by_o its_o help_n for_o eight_o hour_n in_o twenty_o four_o we_o can_v watch_v all_o and_o labour_v most_o of_o the_o other_o sixteen_o all_o the_o day_n of_o our_o life_n it_o follow_v that_o if_o we_o can_v any_o way_n half_o relax_v the_o vigilative_a contraction_n while_o we_o labour_v take_v a_o journey_n or_o the_o like_a that_o we_o may_v perform_v prodigious_o without_o be_v â—ired_v hence_o it_o be_v that_o because_o pleasure_n as_o have_v be_v intimate_v relax_n as_o grievance_n contract_v of_o which_o you_o may_v expect_v far_a proof_n in_o the_o next_o chapter_n that_o such_o as_o work_v or_o travel_n pleasant_o divert_v all_o the_o time_n be_v tire_v very_o little_a or_o nothing_o in_o a_o long_a time_n and_o that_o some_o will_v dance_v whole_a nightâ—_n with_o sweet_a music_n and_o agreeable_a belove_a company_n without_o be_v so_o much_o tire_v as_o they_o will_v be_v if_o they_o use_v the_o same_o motion_n for_o a_o quarter_n of_o the_o time_n without_o either_o of_o the_o pleasant_a diversion_n the_o like_a be_v to_o be_v say_v of_o any_o other_o pleasure_n as_o drink_v a_o good_a glass_n of_o generous_a wine_n every_o half_a hour_n or_o so_o often_o as_o to_o continue_v the_o sense_n of_o its_o pleasure_n at_o stomach_n all_o the_o time_n they_o labour_v or_o travel_v for_o it_o be_v a_o vulgar_a error_n though_o the_o universal_a sentiment_n of_o mankind_n both_o learned_a and_o unlearned_a that_o wine_n cordial_n etc._n etc._n do_v comfort_n elevate_v and_o excite_v the_o spirit_n as_o it_o be_v call_v by_o add_v their_o spirit_n to_o or_o join_v they_o with_o we_o whereas_o it_o be_v only_o by_o cause_v a_o pleasant_a sensation_n particular_o at_o stomach_n for_o which_o paradox_n i_o be_o oblige_v though_o in_o great_a haste_n to_o come_v to_o the_o explication_n of_o opium_n to_o give_v my_o reason_n which_o be_v as_o follow_v viz._n 1._o it_o can_v be_v imagine_v how_o a_o sensitive_a creature_n as_o such_o can_v conceive_v any_o comfort_n or_o be_v sensible_a thereof_o but_o by_o sensation_n to_o say_v he_o be_v comfort_v and_o not_o sensible_a of_o the_o comfort_n be_v a_o contradiction_n for_o comfort_n as_o such_o belong_v to_o a_o perceive_v be_v and_o a_o animal_n as_o such_o perceive_v nothing_o but_o by_o the_o sense_n and_o therefore_o there_o can_v be_v no_o comfort_n but_o by_o pleasant_a sensation_n nay_o as_o such_o it_o be_v his_o comfort_n so_o music_n pleasant_a sight_n odour_n and_o agreeable_a object_n of_o all_o the_o sense_n be_v comfortable_a because_o pleasant_a i_o hope_v that_o none_o will_v say_v that_o music_n sight_n good_a news_n &c._n &c._n which_o high_o comfort_n have_v any_o spirit_n to_o add_v to_o we_o the_o
truth_n be_v that_o god_n and_o nature_n have_v give_v we_o our_o sense_n for_o that_o end_n and_o present_a refection_n in_o case_n of_o faintness_n depression_n of_o spirit_n and_o what_o more_o proper_a to_o convey_v comfort_n to_o we_o than_o what_o be_v sensible_a of_o it_o 2._o it_o be_v another_o thing_n to_o add_v by_o way_n of_o nutrition_n to_o our_o spirit_n which_o be_v insensible_a thing_n and_o therefore_o never_o proper_o comfort_v any_o more_o than_o a_o plant_n that_o be_v nourish_v as_o well_o as_o they_o but_o the_o sensitive_a soul_n be_v please_v must_v needs_o conceive_v satisfaction_n comfort_n joy_n etc._n etc._n how_o he_o can_v be_v please_v when_o sensible_a of_o nothing_o i_o know_v not_o nor_o how_o he_o can_v be_v comfort_v without_o be_v first_o please_v nor_o how_o please_v but_o by_o sensation_n 3._o the_o essence_n of_o animal_n comfort_n do_v not_o consist_v in_o have_v many_o spirit_n for_o one_o in_o most_o grievous_a pain_n and_o misery_n by_o which_o he_o be_v much_o discomfort_a cast_v down_o depress_v in_o spirit_n etc._n etc._n may_v have_v great_a plenty_n of_o spirit_n and_o one_o that_o have_v not_o half_a as_o many_o high_o comfort_v by_o please_a object_n of_o sense_n good_a news_n etc._n etc._n 4._o if_o we_o stay_v for_o comfort_n by_o a_o meal_n of_o meat_n etc._n etc._n till_o it_o add_v to_o our_o spirit_n we_o may_v stay_v long_o enough_o nay_o if_o we_o stay_v for_o comfort_n till_o we_o find_v it_o by_o that_o addition_n we_o shall_v never_o find_v it_o for_o we_o can_v in_o that_o case_n find_v what_o we_o do_v not_o feel_v we_o possible_o after_o two_o or_o three_o day_n eat_v and_o drink_v may_v find_v ourselves_o strong_a but_o after_o all_o suppose_v we_o in_o very_o great_a misery_n at_o the_o same_o time_n where_o be_v the_o comfort_n of_o it_o when_o the_o spirit_n be_v otherwise_o depress_v by_o pain_n ill_a news_n etc._n etc._n 5._o hunger_n be_v a_o grievous_a sensation_n at_o stomach_n which_o be_v cure_v and_o we_o comfort_v by_o cause_v a_o pleasant_a sensation_n by_o meat_n wine_n etc._n etc._n instead_o thereof_o and_o not_o by_o add_v spirit_n which_o be_v a_o great_a mistake_n it_o be_v true_a indeed_o that_o we_o be_v comfort_v but_o it_o be_v most_o manifest_o by_o please_v the_o exquisite_a sensation_n at_o stomach_n which_o god_n have_v place_v there_o for_o that_o end_n hence_o it_o be_v that_o all_o cordial_n must_v be_v please_v to_o the_o stomach_n or_o else_o they_o be_v no_o cordial_n and_o that_o wine_n and_o all_o such_o thing_n as_o please_v the_o stomach_n be_v apt_a to_o take_v away_o much_o of_o the_o sharpness_n of_o hunger_n for_o a_o time_n at_o least_o 6._o how_o shall_v wine_n which_o have_v a_o great_a acidity_n in_o it_o and_o so_o very_o good_a for_o digestion_n cure_v a_o canine_a appetite_n which_o be_v a_o grievous_a sensation_n but_o by_o cause_v a_o pleasant_a one_o in_o its_o room_n by_o which_o mean_v the_o grievous_a sensation_n be_v take_v off_o for_o pleasure_n and_o grievance_n or_o displeasure_n which_o be_v contrary_n can_v be_v in_o the_o same_o subject_a at_o one_o time_n thus_o it_o be_v that_o opium_n take_v off_o hunger_n canine_a appetite_n etc._n etc._n but_o of_o this_o hereafter_o 7._o how_o shall_v a_o quart_n of_o wine_n drink_v in_o a_o minute_n or_o two_o have_v all_o the_o comfortable_a effect_n of_o wine_n in_o a_o quarter_n of_o a_o hour_n while_o it_o be_v at_o stomach_n if_o it_o be_v to_o stay_v for_o this_o comfort_n till_o it_o add_v spirit_n to_o we_o since_o the_o matter_n of_o effluvia_fw-la or_o fume_n pass_v into_o the_o rloud_o be_v disprove_v 8._o why_o shall_v our_o comfort_n be_v so_o great_a while_o it_o be_v at_o stomach_n and_o none_o by_o that_o time_n it_o be_v get_v into_o the_o blood_n but_o that_o the_o stomach_n be_v very_o sensile_a the_o spirit_n of_o the_o wine_n do_v high_o please_v by_o their_o agreeableness_n thereunto_o it_o matter_n not_o whether_o it_o have_v spirit_n or_o no_o so_o it_o cause_v a_o please_a sensation_n for_o a_o draught_n of_o water_n in_o a_o high_a fever_n and_o when_o we_o be_v very_o faint_a with_o thirst_n very_o much_o comfort_v we_o without_o any_o spirit_n as_o do_v a_o venison-pasty_n a_o hungry_a person_n by_o agreeable_a sensation_n take_v off_o the_o grievous_a sensation_n call_v hunger_n and_o all_o its_o consequent_a faintness_n etc._n etc._n before_o it_o can_v add_v any_o spirit_n by_o nutrition_n 9_o what_o need_v we_o seek_v any_o far_a do_v not_o we_o find_v a_o please_a sensation_n at_o stomach_n when_o we_o be_v comfort_v with_o any_o thing_n and_o the_o comfort_n to_o bear_v a_o proportion_n to_o the_o pleasure_n 10._o be_v not_o we_o prompt_v blithe_a gay_a and_o brave_a while_o the_o wine_n be_v at_o stomach_n and_o very_o often_o fit_a for_o nothing_o dull_a heavy_a mopish_a etc._n etc._n by_o that_o time_n it_o be_v get_v into_o the_o blood_n therefore_o we_o may_v safe_o conclude_v that_o the_o spirit_n of_o the_o wine_n do_v comfort_v we_o by_o cause_v a_o please_a sensation_n and_o not_o by_o add_v its_o spirit_n to_o we_o according_a to_o the_o settle_a sentiment_n of_o the_o world_n that_o be_v not_o yet_o arrive_v to_o the_o learning_n or_o knowledge_n why_o the_o most_o common_a cordial_n comfort_v they_o what_o spirit_n have_v a_o grain_n of_o opium_n while_o at_o stomach_n to_o add_v to_o we_o or_o can_v it_o add_v if_o it_o have_v they_o yet_o no_o wine_n comfort_v we_o as_o much_o as_o opium_n because_o it_o please_v we_o so_o much_o as_o be_v and_o will_v be_v yet_o much_o more_o full_o show_v note_v that_o beside_o what_o be_v say_v of_o the_o grievousness_n of_o the_o three_o contraction_n to_o tiâ—e_v the_o animal_n or_o sensitive_a soul_n he_o be_v much_o depress_v and_o cast_v down_o upon_o the_o perception_n of_o grievance_n as_o hunger_n pain_n etc._n etc._n because_o they_o 1._o affect_v he_o with_o grief_n and_o displeasure_n and_o consequent_o with_o discomfort_n anxiety_n etc._n etc._n because_o of_o the_o very_a dolour_n 2._o with_o care_n and_o solicitude_n how_o to_o be_v rid_v of_o it_o 3._o with_o the_o toil_n of_o defensive_a contraction_n to_o endeavour_v it_o all_o which_o cause_v melancholy_a depression_n of_o spirit_n pusillanimity_n perturbation_n fret_n discomposure_n dissatisfaction_n anxiety_n solicitude_n peevishness_n discomposure_n discomfort_n listlesness_n etc._n etc._n as_o you_o see_v in_o such_o as_o be_v hungry_a or_o in_o pain_n to_o which_o if_o you_o add_v the_o fatigue_n and_o effect_n of_o the_o defensive_a contraction_n and_o the_o intentive_a as_o far_o as_o it_o be_v exercise_v for_o self-preservation_n in_o this_o case_n you_o may_v observe_v what_o have_v be_v say_v easy_o solve_v all_o the_o phenomena_n of_o grievous_a sensation_n and_o as_o easy_o conclude_v what_o must_v be_v the_o phenomena_n and_o effect_n of_o pleasant_a sensation_n by_o the_o rule_n of_o contrary_n viz._n satisfaction_n good_a humour_n ease_n comfort_n ovation_n of_o spirit_n relaxation_n etc._n etc._n of_o which_o we_o be_v go_v to_o speak_v chap._n fourteen_o of_o the_o nature_n of_o sensitive_a pleasure_n and_o its_o effect_n upon_o the_o animal_n as_o far_o as_o it_o concern_v our_o present_a purpose_n sensitive_a pleasure_n be_v a_o complacency_n of_o the_o sensitive_a soul_n result_v from_o the_o agreeableness_n of_o the_o object_n to_o the_o organ_n of_o sensation_n thus_o be_v we_o please_v with_o what_o be_v agreeable_a to_o the_o eye_n ear_n tongue_n stomach_n etc._n etc._n and_o what_o be_v agreeable_a to_o those_o organ_n be_v agreeable_a to_o the_o animal_n in_o general_a 1._o because_o god_n have_v make_v and_o appoint_v they_o especial_o the_o sensile_a membrane_n at_o stomach_n to_o be_v as_o it_o be_v the_o touchstone_n of_o what_o be_v agreeable_a to_o the_o animal_n 2._o because_o the_o membrane_n or_o organ_n be_v of_o the_o same_o active_a principle_n with_o the_o animal_n body_n in_o general_a otherwise_o they_o will_v not_o be_v fit_a taster_n trier_n or_o touchstone_n of_o what_o be_v good_a or_o bad_a for_o the_o body_n in_o general_n now_o the_o active_a principle_n of_o the_o membrane_n or_o organ_n be_v volatile_a salt_n and_o oily_a part_n or_o a_o shall_v volatile_a oleosum_fw-la which_o be_v predominant_a in_o they_o and_o all_o the_o part_n of_o the_o body_n therefore_o such_o thing_n as_o have_v a_o volatile_a salt_n join_v with_o some_o oily_a part_n must_v be_v in_o a_o special_a manner_n agreeable_a and_o please_a to_o the_o membrane_n for_o simile_n fimili_fw-la gaudeat_fw-la hence_o it_o be_v that_o what_o abound_v in_o volatile_a salt_n as_o snail_n earthworm_n and_o thing_n of_o that_o kind_n be_v such_o fine_a anodynes_n and_o so_o please_v to_o the_o membrane_n etc._n etc._n that_o the_o seed_n of_o animal_n
often_o cause_v most_o dismal_a and_o tedious_a vomit_n and_o when_o they_o fall_v to_o relieve_v by_o reject_v the_o grieve_v matter_n hiccough_v anxiety_n distress_n syncopes_fw-la and_o sometime_o fatal_a succumbency_n nature_n and_o all_o endeavour_n fail_v to_o work_v any_o far_o for_o the_o animal_n relief_n these_o thing_n happen_v most_o common_o when_o indigeslible_a rosin_n stick_v to_o the_o stomach_n especial_o if_o they_o be_v join_v with_o any_o pungent_a volatile_a or_o acrimonious_a particle_n hence_o it_o be_v that_o resinous_n vomit_n be_v quite_o banish_v out_o of_o the_o practice_n of_o physic_n and_o it_o be_v well_o if_o resinous_n purger_n be_v so_o also_o especial_o such_o as_o have_v considerable_a acrimony_n unless_o give_v with_o the_o yolk_n of_o a_o egg_n lixivial_n or_o in_o tincture_n with_o spirituous_a thing_n to_o keep_v the_o resinous_n particle_n from_o coalescence_n and_o adhere_v to_o the_o stomach_n etc._n etc._n 1._o note_v for_o we_o shall_v have_v some_o occasion_n for_o it_o that_o resinous_n thing_n join_v with_o volatile_a irritate_v particle_n have_v all_o the_o ill_a quality_n aforemention_v viz._n hardness_n of_o digestion_n aptitude_n to_o stick_v to_o the_o stomach_n and_o volatile_a particle_n to_o irritate_fw-la and_o tear_v its_o coat_n all_o the_o time_n they_o so_o stick_v to_o it_o and_o therefore_o such_o thing_n have_v dismal_a effect_n especial_o in_o weak_a stomach_n that_o can_v digest_v they_o 2._o note_v that_o the_o distress_n at_o stomach_n cause_v by_o a_o grievous_a sensation_n be_v of_o two_o sort_n 1._o such_o as_o be_v the_o endeavour_n of_o nature_n or_o the_o sensitive_a soul_n in_o defence_n of_o the_o animal_n as_o all_o vomit_n purge_n convulsion_n hiccough_n throw_n struggle_n agitation_n contraction_n watch_n etc._n etc._n which_o be_v accompany_v with_o melancholy_a fretfulness_n ill_a humour_n etc._n etc._n because_o of_o the_o grievance_n 2._o such_o as_o follow_v the_o yield_v and_o succumbency_n of_o nature_n or_o the_o sensitive_a soul_n after_o be_v tire_v and_o overbear_v by_o the_o fatigue_n of_o defensive_a contraction_n as_o faint_n distress_n agony_n syncopes_fw-la and_o leipothymy_n 3._o note_v that_o syncopes_fw-la or_o leipothymy_n be_v cause_v by_o the_o sensitive_a soul_n be_v overbear_v as_o be_v say_v tire_v and_o spend_v and_o give_v over_o his_o fruitless_a contraction_n defensive_a and_o vigilative_a upon_o a_o sudden_a as_o be_v to_o no_o purpose_n as_o he_o do_v gentle_o and_o gradual_o give_v over_o vigilative_a contraction_n to_o cause_n sleep_n so_o that_o syncopes_fw-la be_v only_o great_a sudden_a and_o more_o absolute_a dereliction_n of_o the_o whole_a concern_v of_o contraction_n hence_o it_o be_v that_o perspiration_n be_v great_a in_o syncopes_fw-la or_o leipothymy_n than_o in_o sleep_n the_o laxity_n of_o the_o cornea_n and_o the_o whole_a body_n great_a the_o feel_v less_o or_o quite_o go_v that_o all_o motion_n become_v much_o slow_a or_o none_o by_o the_o want_n of_o compression_n of_o the_o animal_n spirit_n and_o dismal_a dereliction_n of_o all_o contraction_n by_o the_o sensitive_a soul_n hence_o it_o be_v that_o all_o the_o effect_n of_o sleep_n be_v yet_o great_a in_o syncopes_fw-la 4._o note_v that_o therefore_o it_o seem_v all_o the_o difference_n between_o sleep_n and_o a_o leipothymy_n be_v that_o in_o this_o the_o sensitive_a soul_n quite_o throw_v the_o reins_o of_o contraction_n away_o and_o in_o sleep_n keep_v hold_v thereof_o and_o only_o let_v they_o loose_a and_z as_o refection_n be_v make_v straighten_v they_o more_o and_o more_o till_o they_o come_v to_o the_o degree_n of_o vigilative_a contraction_n which_o perfect_o awake_v they_o therefore_o sleep_n grow_v slight_a towards_o morning_n because_o contraction_n gradual_o come_v on_o here_o you_o may_v see_v but_o i_o must_v stop_v lest_o i_o run_v too_o far_o why_o every_o thing_n that_o cause_v contraction_n of_o the_o sensile_a part_n as_o pain_n and_o all_o grievance_n be_v apt_a to_o awake_a people_n and_o keep_v they_o so_o as_o relaxer_n cause_v sleep_n and_o continue_v it_o 5._o note_v that_o though_o i_o have_v particular_o speak_v of_o the_o somach_n as_o be_v most_o concern_v and_o the_o best_a example_n of_o any_o membrane_n yet_o do_v not_o i_o exclude_v any_o membrane_n from_o be_v capable_a of_o pleasure_n by_o the_o like_a thing_n as_o for_o the_o effect_n of_o pleasure_n upon_o the_o sensitive_a soul_n i_o have_v upon_o several_a occasion_n say_v or_o intimate_v enough_o concern_v they_o and_o even_o the_o vulgar_a know_v that_o pleasure_n or_o be_v please_v make_v people_n good_a and_o gay_a humour_a that_o it_o elevate_v the_o spirit_n raise_v courage_n as_o wine_n do_v and_o enable_v every_o animal_n to_o labour_n or_o travel_v the_o better_a as_o horse_n by_o the_o sound_n of_o bell_n especial_o if_o tuneable_a and_o in_o company_n with_o another_o horse_n that_o they_o have_v a_o kindness_n for_o how_o soldier_n march_v more_o easy_o with_o merry_a comrade_n that_o be_v full_a of_o jest_n and_o pleasant_a story_n or_o with_o drum_n trumpets_z kettle_z drums_z 〈◊〉_d and_o other_o music_n that_o please_v the_o ear_n how_o much_o more_o briâ—k_n and_o blithe_a be_v we_o in_o a_o fair_a sunshine_n which_o please_v the_o eye_n than_o at_o other_o time_n some_o â—ink_n according_a to_o the_o vulgar_a error_n that_o iâ—_n be_v the_o goodness_n of_o the_o air_n do_v it_o but_o it_o be_v plain_o otherwise_o for_o you_o find_v the_o change_n most_o remarkable_a in_o yourself_o just_a upon_o go_v out_o of_o door_n into_o the_o sunshine_n whereas_o you_o have_v the_o same_o air_n in_o your_o chamber_n nor_o be_v that_o fine_a lightness_n of_o humour_n to_o be_v find_v if_o it_o be_v cloudy_a though_o the_o air_n be_v better_o as_o may_v be_v observe_v by_o the_o barometer_n and_o other_o weather-glass_n nor_o in_o the_o night_n time_n nor_o where_o the_o sun_n do_v not_o come_v nor_o be_v blind_a people_n so_o affect_v therefore_o it_o be_v the_o pleasure_n of_o the_o bright_a sunshine_n that_o cause_v it_o if_o mean_a 'slight_o transient_a and_o external_n pleasure_n cause_v such_o effect_n how_o much_o more_o than_o will_v a_o intense_a internal_a and_o continue_a pleasure_n upon_o the_o most_o exquisite_o dispose_v part_n for_o sensation_n of_o all_o the_o whole_a body_n which_o be_v main_o design_v for_o those_o purpose_n of_o please_a and_o comfort_v to_o invite_v we_o to_o nourish_v ourselves_o and_o to_o satisfy_v the_o grievous_a sensation_n of_o hunger_n and_o thirst_n by_o the_o pleasure_n of_o meat_n and_o drink_n such_o pleasant_a effect_n thus_o the_o fretfulness_n peevishness_n ill_a humour_n melancholy_n pusillanimity_n inaptitude_n and_o listnesness_n that_o attend_v the_o grievous_a sensation_n of_o hunger_n be_v take_v off_o and_o cure_v by_o the_o pleasant_a sensation_n that_o a_o good_a meal_n or_o some_o glass_n of_o wine_n do_v cause_n hence_o it_o be_v that_o we_o can_v sleep_v when_o hungry_a because_o grievous_a sensation_n contract_v the_o sensile_a part_n and_o be_v apt_a to_o it_o after_o meal_n the_o pleasure_n of_o which_o relax_n we_o if_o we_o sit_v or_o lie_v quiet_o and_o silent_o but_o if_o we_o do_v not_o we_o be_v more_o lively_a and_o fit_a for_o business_n instance_n of_o this_o kind_a be_v so_o numerous_a and_o notorious_a that_o i_o need_v say_v no_o more_o of_o the_o effect_n of_o pleasure_n in_o cause_v a_o good_a humour_n elevation_n of_o the_o spirit_n satisfaction_n content_a composure_n etc._n etc._n be_v it_o possible_a that_o one_o shall_v be_v high_o please_v and_o not_o take_v comfort_n therein_o take_v comfort_n and_o not_o be_v elevate_v in_o spirit_n well_o satisfy_v and_o content_v therefore_o it_o be_v strange_a and_o very_o strange_a that_o people_n shall_v leave_v wine_n cordial_n meat_n spirit_n etc._n etc._n actual_o and_o sensible_o please_v satisfy_a and_o comfort_v we_o at_o stomach_n where_o there_o be_v a_o membrane_n most_o exquisite_o dispose_v for_o sensation_n and_o run_v after_o fume_n and_o effluvias_fw-la that_o be_v never_o in_o our_o case_n in_o be_v to_o the_o brain_n or_o blood_n that_o have_v no_o sense_n to_o entertain_v they_o and_o consequent_o can_v receive_v no_o sensible_a comfort_n by_o they_o if_o this_o be_v not_o seek_v a_o needle_n in_o a_o bottle_n of_o hay_n where_o it_o never_o be_v when_o it_o stick_v most_o sensible_o in_o their_o finger_n nothing_o be_v we_o shall_v think_v it_o a_o strange_a ridiculous_a action_n in_o a_o child_n or_o natural_a fool_n but_o great_a be_v the_o privilege_n and_o authority_n of_o the_o learned_a so_o much_o may_v suffice_v as_o to_o the_o effect_n of_o pleasure_n upon_o the_o sensitive_a soul_n as_o for_o the_o effect_n of_o pleasure_n upon_o the_o body_n it_o be_v relaxation_n of_o all_o the_o sensile_a part_n thereof_o as_o appear_v 1._o because_o it_o be_v contrary_a viz._n displeasure_n or_o sensitive_a
by_o diminish_v or_o disable_n the_o spirit_n except_o it_o be_v that_o the_o pernicious_a rosin_n may_v do_v something_o of_o that_o kind_n by_o its_o aforesaid_a ill_a effect_n but_o by_o pleasant_o affect_v the_o membrane_n at_o stomach_n venereal_a part_n etc._n etc._n 2._o that_o sleep_n be_v cause_v by_o relaxation_n and_o quiet_v the_o spirit_n 3._o that_o pleasure_n especial_o if_o intense_a and_o last_a as_o that_o by_o opium_n comfort_n enlivens_fw-la encourage_v and_o cause_v a_o ovation_n of_o the_o sensitive_a soul_n and_o spirit_n and_o displeasure_n cause_v sadness_n dejection_n etc._n etc._n 4._o how_o pleasure_n must_v cause_v complacency_n satisfaction_n content_a acquiescence_n and_o composure_n of_o the_o sensitive_a soul_n and_o spirit_n as_o grievance_n cause_v the_o contrary_n 5._o how_o pleasure_n elevate_a and_o keep_v up_o the_o spirit_n and_o cause_v a_o entire_a relaxation_n of_o the_o defensive_a and_o a_o great_a relaxation_n of_o the_o vigilative_a contraction_n which_o tire_v the_o sensitive_a soul_n must_v cause_v euphory_n or_o easy_a undergo_n of_o labour_n journey_n etc._n etc._n without_o lassitude_n as_o experience_n show_v 6._o how_o pleasure_n cause_v relaxation_n of_o all_o the_o sensile_a part_n 7._o how_o the_o say_a relaxation_n as_o in_o sleep_n do_v by_o suffer_v the_o animal_n spirit_n to_o expand_v and_o thereby_o make_v they_o unfit_a to_o carry_v impression_n smart_o which_o be_v necessary_a to_o convey_v a_o sense_n of_o pain_n for_o a_o smart_a impression_n be_v the_o very_a cause_n of_o it_o take_v away_o pain_n to_o which_o you_o may_v add_v that_o the_o sensitive_a soul_n attend_v willing_o to_o the_o sense_n of_o pleasure_n be_v divert_v from_o pain_n and_o that_o a_o sense_n of_o pain_n can_v be_v in_o the_o same_o subject_a with_o pleasure_n which_o be_v therefore_o once_o excite_v pain_n must_v disappear_v but_o that_o of_o take_v away_o all_o smartness_n of_o impression_n by_o relaxation_n be_v a_o plain_a mechanical_a cause_n 8._o how_o therefore_o all_o flux_n that_o be_v cause_v by_o or_o require_v a_o grievous_a sensation_n or_o irritation_n by_o quantity_n or_o quality_n to_o maintain_v and_o continue_v they_o by_o cause_v a_o contraction_n of_o the_o part_n to_o squeeze_v out_o the_o humour_n must_v be_v moderate_v for_o want_v of_o sensation_n upon_o such_o relaxation_n to_o irritate_fw-la the_o part_n as_o it_o happen_v in_o sleep_n or_o in_o any_o case_n where_o relaxation_n and_o thereby_o expansion_n of_o the_o animal_n spirit_n incapacitates_fw-la they_o to_o carry_v impression_n smart_o which_o be_v of_o the_o essence_n of_o pain_n as_o have_v be_v show_v 9_o how_o perspiration_n must_v be_v promote_v by_o relaxation_n which_o open_v the_o pore_n 10._o how_o that_o by_o the_o same_o mean_n sweat_v also_o must_v be_v promote_v if_o the_o body_n be_v full_a of_o moisture_n 11._o how_o opium_n or_o semen_n animale_a be_v of_o the_o same_o principle_n and_o of_o like_a principle_n with_o cantharides_n pismire_n bee_n garlick_n etc._n etc._n must_v excite_v to_o venery_n cause_n itch_n of_o the_o skin_n etc._n etc._n 12._o how_o opium_n may_v by_o too_o high_a a_o ovation_n of_o the_o spirit_n cause_n watch_v while_o pleasure_n cause_v relaxation_n etc._n etc._n may_v take_v away_o pain_n for_o relaxation_n as_o in_o sleep_n syncopes_fw-la etc._n etc._n be_v enough_o to_o take_v away_o pain_n but_o to_o sleep_v quietness_n of_o the_o spirit_n be_v also_o require_v as_o well_o as_o their_o expansion_n by_o relaxation_n so_o that_o pain_n may_v very_o well_o be_v take_v off_o without_o sleep_n as_o it_o often_o be_v by_o opium_n that_o always_o relax_n 13._o how_o the_o pleasure_n that_o opium_n cause_n be_v as_o be_v say_v by_o the_o same_o principle_n and_o therefore_o of_o the_o same_o nature_n with_o that_o which_o animal_n seed_n cause_v upon_o the_o membrane_n but_o that_o animal_n seed_n cause_v it_o only_o upon_o one_o part_n and_o opium_n upon_o the_o membrane_n of_o the_o stomach_n venereal_a part_n and_o all_o other_o in_o general_n and_o that_o only_a for_o a_o moment_n but_o this_o of_o opium_n for_o many_o hour_n by_o which_o mean_v the_o effect_n of_o relaxtion_n by_o pleasure_n come_v to_o be_v more_o remarkable_a as_o after_o much_o wine_n who_o effect_n be_v somewhat_o last_v and_o internal_a as_o that_o of_o opium_n be_v 14._o how_o the_o rosin_n of_o opium_n cause_v its_o ill_a effect_n by_o its_o indigestibleness_n adhere_v quality_n and_o tedious_a sting_a of_o the_o exquisite_o nice_a coat_n of_o the_o stomach_n by_o continual_o teaze_v and_o urge_v it_o by_o its_o actimony_n and_o acute_a volatile_a point_n or_o spiculâ—_n therefore_o have_v 1._o a_o most_o perfect_a and_o complete_a sol-volatile-oleosum_a in_o opium_n of_o the_o same_o please_a principle_n as_o to_o all_o membrane_n as_o animal_n seed_n be_v to_o the_o membrane_n of_o venus_n whereby_o they_o must_v be_v please_v tickle_v and_o relax_v 2._o a_o pernicious_a rosin_n indigestible_a stick_v and_o arm_v with_o acrimonious_a and_o sting_a point_n which_o must_v high_o offend_v the_o most_o sensile_a coat_n at_o the_o stomach_n i_o be_o now_o ready_a by_o god_n assistance_n to_o explain_v every_o phenomenon_n or_o effect_v of_o opium_n however_o amaze_a and_o mysterious_a hope_v they_o will_v not_o remain_v long_o so_o chap._n xvi_o the_o explication_n of_o the_o effect_n of_o opium_n use_v external_o its_o effect_n external_o use_v be_v of_o two_o sort_n either_o i._o as_o a_o opiate_n or_o please_a tickler_n of_o the_o membrane_n or_o ii_o as_o a_o alterative_a of_o the_o part_n that_o it_o be_v apply_v to_o first_o as_o a_o opiate_n or_o pleaser_n of_o the_o membrane_n it_o have_v the_o same_o effect_n as_o opium_n use_v internal_o and_o for_o the_o same_o reason_n therefore_o the_o cause_n of_o its_o operation_n in_o this_o case_n will_v be_v better_o see_v by_o the_o explication_n of_o its_o internal_a effect_n which_o be_v far_o more_o perfect_a complete_a and_o certain_a second_o as_o a_o alterative_a of_o the_o part_n that_o it_o be_v apply_v to_o which_o be_v the_o follow_v viz._n 1._o it_o incides_fw-la resolve_n and_o discuss_n by_o its_o point_a penetrate_a and_o volatile_a salt_n insinuate_v itself_o into_o the_o part_n and_o humour_n of_o the_o animal_n because_o its_o particle_n be_v fine_a minute_n and_o agreeable_a thereto_o as_o menstruum_n to_o the_o thing_n to_o be_v dissolve_v then_o by_o its_o volatility_n it_o discuss_n what_o it_o have_v so_o incide_v and_o resolve_v 2._o it_o mollefy_v and_o relax_n by_o its_o sal-volatile-oleosum_a so_o resolve_v the_o part_n and_o humour_n and_o thereby_o kindly_a loosen_a they_o thus_o opiate_n as_o solanum_fw-la lethale_n or_o deadly_a night_n shade_n hemlock_n mandrake_n etc._n etc._n come_v to_o be_v of_o excellent_a use_n in_o hard_a tumor_n of_o the_o spleen_n tophousness_n etc._n etc._n 3._o it_o maturate_v and_o suppurate_v for_o the_o aforesaid_a reason_n for_o nothing_o can_v better_v dispose_n towards_o maturation_n and_o suppuration_n than_o relax_v mollefy_a and_o resolve_v 4._o it_o exulcerate_v or_o cause_n blister_n or_o at_o least_o rubify_v tender_a skin_n if_o it_o be_v very_o strong_a because_o of_o its_o volatile_a salt_n as_o cantharides_n spearwort_n and_o other_o thing_n do_v upon_o the_o same_o account_n but_o this_o effect_n belong_v main_o to_o the_o true_a mastack_n or_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o drop_n from_o the_o incision_n make_v in_o the_o head_n of_o the_o poppy_n more_o especial_o the_o theban_a which_o afford_v a_o most_o powerful_a juice_n for_o exulcerate_v or_o blister_v be_v but_o a_o strong_a full_a and_o therefore_o painful_a resolution_n as_o you_o see_v by_o the_o cuticle_n upon_o blister_n resolve_v into_o a_o kind_n of_o jelly_n 5._o it_o be_v psilothrick_n for_o the_o same_o reason_n for_o while_o it_o so_o resolve_v the_o part_n it_o loosen_v the_o root_n of_o the_o hair_n and_o so_o cause_v its_o shed_n 6._o it_o hurt_v the_o eye_n because_o of_o its_o acrimony_n by_o reason_n of_o the_o volatile_a salt_n 7._o it_o cause_v itch_a in_o the_o skin_n by_o the_o titillation_n of_o the_o same_o volatile_a salt_n as_o you_o find_v by_o the_o application_n of_o squill_n and_o the_o like_a 8._o it_o excite_v venery_n by_o the_o same_o titillation_n on_o the_o veneral_a membrane_n chap._n xvii_o the_o explication_n of_o the_o effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v note_v that_o because_o opium_n have_v be_v general_o hitherto_o use_v either_o crude_a or_o with_o its_o rosin_n in_o it_o the_o effect_n of_o opium_n be_v according_o consider_v as_o common_a experience_n thereupon_o have_v give_v opportunity_n of_o observe_v they_o but_o as_o i_o proceed_v i_o shall_v show_v you_o where_o the_o resinous_n part_n of_o opium_n be_v concern_v in_o the_o effect_n 1._o it_o be_v manifest_a why_o opium_n may_v well_o
best_a part_n of_o opium_n which_o be_v so_o much_o the_o better_a the_o more_o it_o abound_v with_o they_o 9_o if_o it_o yield_v any_o other_o tincture_n than_o red_a it_o be_v not_o right_a and_o the_o dull_a or_o pale_a the_o red_a be_v the_o worse_a or_o weak_a it_o be_v 10._o the_o best_a be_v heavy_a in_o proportion_n to_o its_o bulk_n which_o you_o may_v soon_o experiment_n thus_o weigh_v a_o ounce_n of_o each_o in_o the_o air_n then_o weigh_v they_o just_a as_o they_o be_v in_o the_o brass_n scales_n in_o water_n and_o the_o heavy_a will_n outweigh_v the_o other_o in_o water_n for_o the_o heavy_a any_o thing_n be_v the_o less_o water_n take_v from_o its_o weight_n in_o proportion_n to_o its_o bulk_n this_o be_v a_o infallible_a and_o most_o ready_a way_n to_o know_v the_o weight_n of_o any_o thing_n in_o proportion_n to_o its_o bulk_n note_v that_o my_o discourse_n be_v most_o particular_o concern_v the_o best_a sort_n of_o crude_a turkey_n opium_n that_o be_v the_o best_a that_o we_o have_v in_o common_a use_n and_o that_o its_o effect_n and_o not_o those_o of_o any_o preparation_n thereof_o be_v set_v down_o in_o the_o follow_a chapter_n chap_n iii_o the_o effect_n of_o opium_n use_v external_o opium_n use_v external_o have_v two_o sort_n of_o effect_n upon_o a_o humane_a body_n 1._o as_o a_o opiate_n to_o cause_n sleep_n take_v away_o pain_n etc._n etc._n 2._o as_o a_o alterative_a of_o the_o part_n it_o be_v apply_v to_o i._o as_o a_o opiate_n it_o be_v of_o very_o uncertain_a and_o uneven_a effect_n when_o apply_v external_o for_o sometime_o it_o cause_v sleep_n take_v away_o pain_n but_o it_o often_o fail_v therefore_o it_o be_v general_o much_o better_a safe_a more_o certain_a and_o effectual_a to_o use_v it_o internal_o i_o do_v scarce_o know_v the_o case_n wherein_o it_o be_v better_a to_o use_v it_o external_o than_o internal_o unless_o it_o be_v to_o smell_v to_o in_o some_o case_n but_o of_o these_o thing_n more_o particular_o when_o we_o come_v to_o the_o use_v of_o opium_n in_o cure_v prevent_v or_o paliate_a disease_n for_o here_o we_o only_o lie_v down_o effect_n in_o order_n to_o a_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n to_o which_o its_o internal_a effect_n will_v main_o contribute_v however_o it_o may_v be_v very_o useful_a to_o that_o end_n to_o lay_v down_o its_o alterative_a effect_n for_o thereby_o we_o shall_v in_o good_a measure_n know_v the_o prin_fw-mi ciple_n by_o which_o it_o operate_v ii_o it_o be_v external_a effect_n as_o a_o alterative_a be_v these_o viz._n 1._o it_o incides_fw-la resolve_n and_o discuss_n 2._o it_o relax_n and_o mollify_v 3._o it_o maturate_v and_o suppurate_v 4._o it_o exulcerate_v or_o cause_n blister_n if_o it_o be_v very_o strong_a and_o apply_v to_o person_n of_o a_o fine_a texture_n where_o the_o skin_n be_v tender_a but_o this_o effect_n belong_v more_o proper_o to_o the_o maslack_n or_o true_a 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o drop_n from_o the_o incision_n make_v in_o the_o head_n of_o the_o poppy_n especial_o the_o theban_a which_o afford_v a_o very_a powerful_a juice_n hence_o you_o may_v observe_v that_o the_o more_o it_o exulcerates_n or_o blister_n the_o better_a be_v the_o opium_n &_o vice_fw-la versâ_fw-la 5._o it_o be_v a_o psilotherick_n for_o it_o prevent_v hair_n to_o grow_v and_o cause_v the_o shed_v thereof_o 6._o it_o be_v hurtful_a to_o the_o eye_n and_o ear_n 7._o it_o excite_v itch_n apply_v in_o a_o moderate_a manner_n to_o the_o skin_n 8._o it_o excite_v venery_n apply_v to_o the_o perinaeum_n chap._n iu._n the_o effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o the_o moderate_a do_v in_o ordinary_a use_n to_o produce_v the_o follow_a effect_n be_v from_o one_o to_o three_o grain_n more_o or_o less_o according_a to_o the_o circumstance_n condition_n case_n constitution_n age_n &c_n &c_n of_o the_o person_n who_o take_v it_o 2._o it_o operate_v general_o in_o a_o short_a time_n after_o it_o be_v in_o the_o stomach_n that_o be_v in_o about_o half_a a_o hour_n more_o or_o less_o if_o take_v in_o a_o liquid_a form_n and_o in_o about_o a_o hour_n more_o or_o less_o if_o in_o a_o solid_a form_n drink_v a_o draught_n of_o water_n or_o some_o liquor_n after_o it_o otherwise_o it_o may_v be_v sometime_o near_o a_o hour_n and_o a_o half_a before_o it_o have_v its_o full_a effect_n but_o the_o time_n of_o its_o operation_n have_v a_o considerable_a latitude_n according_a to_o the_o disposition_n of_o the_o stomach_n and_o other_o circumstance_n as_o the_o vehicle_n it_o be_v take_v in_o etc._n etc._n the_o constant_a effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o diffuse_v itself_o in_o a_o kind_n of_o indefinite_a manner_n seizing_z one_o not_o unlike_o the_o gentle_a sweet_a deliquium_fw-la that_o we_o find_v upon_o our_o entrance_n into_o a_o most_o agreeable_a slumber_n which_o upon_o yield_v to_o it_o general_o end_v in_o sleep_n but_o if_o the_o person_n keep_v himself_o in_o action_n discourse_n or_o business_n it_o seem_v especial_o when_o give_v in_o a_o mornning_a after_o a_o moderate_a rest_n at_o night_n like_o a_o most_o delicious_a and_o extraordinary_a refreshment_n of_o the_o spirit_n upon_o very_o good_a news_n or_o any_o other_o great_a cause_n of_o joy_n as_o the_o sight_n of_o a_o dear_o belove_a person_n etc._n etc._n thought_n to_o have_v be_v lose_v at_o sea_n or_o the_o like_a cause_v such_o a_o pleasant_a ovation_n of_o the_o spirit_n serenity_n etc._n etc._n as_o we_o find_v after_o a_o competent_a measure_n of_o generous_a wine_n ad_fw-la hilaritatem_fw-la as_o man_n use_v to_o say_v it_o be_v indeed_o so_o unexpressible_o fine_a and_o sweet_a a_o pleasure_n that_o it_o be_v very_o difficult_a for_o i_o to_o describe_v or_o any_o to_o conceive_v it_o but_o such_o as_o actual_o feel_v it_o for_o it_o be_v as_o if_o a_o good_a genius_n possess_v or_o inform_v a_o man_n therefore_o people_n do_v common_o call_v it_o a_o heavenly_a condition_n as_o if_o no_o worldly_a pleasure_n be_v to_o be_v compare_v with_o it_o helmontianus_fw-la will_v doubtless_o express_v it_o by_o the_o archaeus_n in_o his_o very_a best_a humour_n it_o have_v be_v compare_v not_o without_o good_a cause_n to_o a_o permanent_a gentle_a degree_n of_o that_o pleasure_n which_o modesty_n forbid_v the_o name_n of_o and_o it_o be_v well_o worth_a a_o remark_n that_o both_o be_v pleasure_n of_o the_o same_o sense_n viz._n that_o of_o feel_v for_o it_o can_v be_v a_o pleasure_n of_o any_o other_o sense_n since_o it_o be_v internal_a 2._o it_o cause_v a_o brisk_a gay_a and_o good_a humour_n nor_o do_v i_o doubt_v but_o it_o have_v this_o effect_n upon_o sleep_a person_n as_o far_o as_o their_o condition_n be_v capable_a of_o observe_v it_o for_o you_o shall_v have_v they_o often_o tell_v of_o pleasant_a dream_n after_o it_o when_o they_o remember_v they_o and_o speak_v of_o any_o see_v bauchin_n and_o the_o author_n mention_v below_o under_o the_o four_o effect_n of_o opium_n 3._o it_o cause_v promptitude_n serenity_n alacrity_n and_o expediteness_n in_o dispatch_v and_o manage_n of_o business_n to_o which_o end_n and_o that_o of_o a_o good_a and_o gay_a humour_n which_o be_v near_o of_o kind_n it_o be_v common_o take_v in_o the_o morning_n in_o the_o eastern_a country_n with_o most_o certain_a effect_n the_o truth_n of_o which_o wedelius_n be_v force_v to_o confess_v though_o quite_o contrary_a to_o his_o hypothesis_n of_o opium_n fix_v and_o coagulate_v the_o spirit_n give_v a_o instance_n of_o a_o certain_a serene_a person_n who_o when_o she_o have_v any_o affair_n of_o great_a moment_n to_o dispatch_v do_v beforehand_o take_v opium_n with_o great_a advantage_n for_o she_o thereby_o find_v herself_o every_o way_n better_o dispose_v for_o business_n and_o more_o enable_v to_o bear_v the_o fatigue_n thereof_o which_o be_v the_o substance_n of_o what_o he_o write_v in_o latin_n many_o other_o author_n confirm_v the_o truth_n of_o these_o effect_n but_o above_o all_o the_o constant_a experience_n of_o the_o eastern_a nation_n put_v it_o out_o of_o all_o doubt_n 4._o it_o cause_v assurance_n ovation_n of_o the_o spirit_n courage_n contempt_n of_o danger_n and_o magnanimity_n much_o after_o the_o manner_n that_o generous_a wine_n do_v instead_o of_o which_o the_o turk_n etc._n etc._n use_v opium_n before_o engagement_n desperate_a attack_n etc._n etc._n as_o be_v most_o notorious_a to_o make_v they_o courageous_a which_o it_o certain_o do_v for_o your_o satisfaction_n as_o to_o this_o and_o other_o effect_n of_o opium_n not_o so_o common_o observe_v
with_o we_o for_o reason_n give_v in_o chap._n viii_o see_v bellonius_fw-la l._n 3._o c._n 15._o p._n 179._o erastus_n disp._n de_fw-fr sapor_n p._n 6â—_n georg._n andreae_n itenerar_n ind._n l._n 2._o c._n 9_o p._n 12._o camerar_fw-it oper._n subcis_n l._n 1._o c._n 93._o p._n 437._o erastus_n disp._n de_fw-fr narcot_n oberndorf_n historian_n also_o add_v that_o when_o the_o great_a turk_n make_v a_o considerable_a war_n the_o soldier_n buy_v up_o all_o or_o most_o of_o the_o opium_n which_o may_v be_v worth_a a_o merchant_n observation_n for_o it_o thereupon_o grow_v dear_a and_o be_v much_o cheap_a in_o time_n of_o peace_n 5._o it_o prevent_v and_o take_v away_o grief_n fear_v anxiety_n peevishness_n fretfulness_n etc._n etc._n these_o be_v necessary_a consequence_n of_o the_o former_a effect_n 6._o it_o cause_v euphory_n or_o easy_a undergo_n of_o all_o labour_n journey_n etc._n etc._n and_o that_o far_o beyond_o all_o wine_n and_o hot_a cordial_n or_o spirit_n therefore_o it_o be_v very_o much_o use_v in_o turkey_n and_o the_o eastern_a country_n in_o laborious_a undertake_n great_a journey_n etc._n etc._n which_o man_n perform_v by_o the_o help_n of_o opium_n after_o a_o prodigious_a and_o almost_o incredible_a manner_n but_o the_o matter_n of_o fact_n be_v so_o common_a and_o usual_a that_o there_o be_v no_o place_n of_o doubt_n beside_o that_o some_o who_o try_v it_o among_o we_o have_v find_v it_o so_o 7._o it_o lull_v soothe_v and_o as_o it_o be_v charm_v the_o mind_n with_o satisfaction_n acquiescence_n contentation_n equanimity_n etc._n etc._n how_o shall_v it_o fail_v to_o cause_v these_o effect_n since_o it_o cause_v all_o the_o former_a gay_a pleasant_a and_o brave_a humour_n dr._n willis_n and_o other_o have_v no_o true_a experience_n or_o knowledge_n of_o opium_n imagine_v that_o it_o cause_v courage_n bravery_n equanimity_n etc._n etc._n by_o stupify_a the_o sense_n brain_n etc._n etc._n make_v people_n inadvertent_n dull_a and_o inapprehensive_a which_o be_v a_o great_a mistake_n and_o a_o groundless_a conceit_n for_o it_o be_v a_o most_o certain_a truth_n which_o million_o can_v affirm_v that_o it_o produce_v those_o effect_n by_o a_o ovation_n and_o pleasure_n of_o the_o sensitive_a soul_n and_o spirit_n as_o generous_a wine_n do_v before_o man_n be_v suddle_v or_o overcome_v with_o it_o how_o else_o can_v they_o at_o the_o same_o time_n be_v more_o serene_a and_o apt_a for_o the_o management_n of_o any_o business_n and_o neat_a dispatch_n of_o affair_n as_o it_o be_v most_o certain_a they_o be_v these_o fundamental_a mistake_v about_o opium_n have_v be_v as_o you_o will_v find_v hereafter_o one_o great_a cause_n why_o its_o operation_n have_v puzzle_v and_o quite_o baffle_v all_o enquirer_n 8._o it_o quiet_v allay_v and_o compose_v all_o perturbation_n and_o commotion_n of_o the_o spirit_n or_o sensitive_a soul_n blood_n humour_n etc._n etc._n as_o in_o hysterical_a case_n diary_n fever_n that_o proceed_v from_o passion_n as_o anger_n grief_n terror_n etc._n etc._n from_o violent_a motion_n labour_n heat_v journey_n convulsion_n etc._n etc._n or_o from_o pain_n and_o stop_v bleedings_a that_o proceed_v from_o such_o commotion_n 9_o it_o cause_v a_o relaxation_n of_o all_o the_o sensible_a part_n of_o the_o body_n as_o the_o membranous_a and_o nervous_a this_o be_v notorious_a by_o its_o effect_n as_o cause_v perspiration_n sweat_v relaxation_n of_o sphincter_n vilatation_n of_o the_o pupil_n of_o the_o eye_n relaxation_n of_o the_o cornea_n and_o all_o other_o effect_n of_o relaxation_n as_o you_o will_v find_v more_o particular_o hereafter_o 10._o it_o cause_v indolence_n or_o exemption_n from_o pain_n as_o all_o know_v and_o allow_v and_o that_o when_o sleep_n do_v not_o intervene_v 11._o it_o stop_v moderate_v cure_n or_o paliate_v all_o flux_n except_v those_o by_o the_o pore_n or_o such_o as_o depend_v as_o that_o do_v upon_o relaxation_n as_o when_o sphincter_n be_v weak_a or_o paralytical_a but_o these_o last_o be_v unnatural_a accident_n 12._o it_o mighty_o promote_v insensible_a perspiration_n 13._o it_o prevent_v shivering_n in_o ague-fits_a and_o suchlike_a case_n if_o give_v in_o due_a time_n and_o quantity_n which_o shall_v be_v show_v in_o the_o curative_fw-it part._n 14._o it_o prevent_v and_o cure_v cold_n 15._o it_o cause_v a_o large_a and_o slow_a pulse_n suppose_v no_o accidental_a cause_n to_o the_o contrary_n 16._o it_o cause_v dryness_n in_o the_o mouth_n 17._o it_o have_v most_o effect_n in_o warm_a and_o moist_a wether_n 18._o it_o have_v more_o effect_n upon_o lax_n and_o fine_a textured_a person_n as_o woman_n child_n etc._n etc._n therefore_o woman_n seldom_o use_v it_o in_o turkey_n and_o the_o other_o eastern_a country_n where_o it_o be_v common_o use_v by_o the_o men._n 19_o it_o cause_v a_o efflorescence_n of_o the_o skin_n bar_v accident_n of_o cold_a etc._n etc._n 20._o it_o be_v observe_v by_o all_o that_o it_o main_o affect_v the_o genus_fw-la nervosum_fw-la and_o animal_n spirit_n and_o not_o the_o blood_n and_o humour_n 21._o it_o increase_v seed_n in_o some_o measure_n 22._o it_o cause_v a_o great_a promptitude_n to_o venery_n erection_n etc._n etc._n especial_o if_o the_o do_v be_v large_a than_o ordinary_a which_o i_o will_v have_v man_n believe_v without_o experiment_v it_o not_o that_o i_o fear_v to_o be_v confute_v but_o lest_o any_o shall_v injure_v themselves_o by_o too_o great_a a_o do_v this_o be_v one_o great_a cause_n if_o not_o the_o chief_a why_o the_o infidel_n of_o turkey_n and_o the_o eastern_a nation_n especial_o where_o polygamy_n be_v allow_v as_o among_o the_o turk_n etc._n etc._n use_v opium_n so_o much_o it_o never_o â—ailing_v to_o produce_v this_o effect_n in_o hale_v and_o healthy_a people_n if_o the_o do_v be_v sufficient_a as_o be_v too_o notorious_a in_o all_o or_o most_o country_n from_o greece_n to_o japan_n inclusive_o who_o use_v opium_n for_o that_o end_n but_o as_o to_o the_o truth_n of_o this_o effect_n of_o opium_n not_o only_o author_n and_o all_o the_o people_n of_o those_o eastern_a nation_n but_o several_a merchant_n factor_n and_o traveller_n now_o live_v in_o london_n can_v attest_v that_o it_o be_v use_v for_o that_o purpose_n in_o those_o country_n with_o effect_n yea_o some_o in_o our_o own_o nation_n that_o use_v opium_n in_o large_a dose_n can_v attest_v the_o same_o upon_o experience_n in_o their_o own_o body_n those_o who_o desire_v to_o be_v satisfy_v may_v also_o read_v joh._n jacob_n saar_n his_o itinerar_n ind._n p._n 11._o olearius_n â—tinerar_n persio_fw-la l._n 5._o c._n 15._o &_o 18._o b._n d._n d._n sack_n tom._n 11._o epher_n german_n obs._n 69._o p._n 126._o bauchin_n p._n 450._o cardanus_n scaliger_n nich._n monordei_n fogâ—lius_fw-la de_fw-la turcarum_fw-la nepenthe_n bellonius_fw-la and_o other_o who_o word_n i_o do_v not_o repeat_v partly_o for_o modesty_n partly_o for_o brevity_n sake_n it_o do_v i_o confess_v look_v like_o a_o riddle_n that_o a_o most_o relax_a and_o stupify_a medicament_n which_o take_v away_o much_o of_o the_o sense_n of_o feel_v and_o consequent_o irritation_n to_o venery_n as_o one_o will_v think_v shall_v notwithstanding_o irritate_fw-la thereunto_o cause_n erection_n etc._n etc._n however_o it_o be_v most_o certain_a though_o a_o seem_a contradiction_n of_o which_o sort_n you_o have_v many_o more_o among_o the_o effect_n of_o opium_n usual_a and_o frequent_a though_o not_o constant_a effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o sleep_v which_o be_v so_o far_o from_o be_v a_o constant_a effect_n of_o opium_n that_o it_o will_v in_o i_o and_o many_o other_o person_n prevent_v sleep_v even_o when_o otherwise_o incline_v to_o it_o 2._o pleasant_n dream_n 3._o stop_v of_o vomit_n 4._o still_v the_o hiccough_n 5._o take_v off_o convulsion_n and_o contraction_n 6._o cause_v meat_n to_o stay_v long_o at_o stomach_n 7._o moderation_n and_o prevention_n of_o hunger_n 8._o sweat_n 9_o the_o flow_v of_o the_o menses_fw-la though_o not_o observe_v by_o vulgar_a physician_n 10._o the_o flow_v of_o the_o lochia_n which_o be_v as_o little_o observe_v 11._o void_v of_o the_o stone_n 12._o delivery_n of_o woman_n 13._o deadness_n of_o the_o eye_n as_o you_o see_v in_o drunkenness_n 14._o dilatation_n of_o the_o pupil_n 15._o growth_n of_o the_o breast_n penis_n and_o increase_v of_o milk_n 16._o veneral_a dream_n 17._o nocturnal_a pollution_n 18._o itch_n in_o the_o skin_n 19_o much_o urine_n 20._o nausea_n 21._o swimmings_n in_o the_o head_n 22._o watch_v 23._o a_o kind_n of_o dubious_a state_n between_o sleep_v and_o wake_v 24._o it_o stop_v hemorrhage_n in_o many_o case_n many_o more_o instance_n of_o this_o kind_n may_v be_v give_v of_o its_o frequent_a and_o usual_a effect_n in_o disease_n but_o it_o will_v be_v endless_a and_o needless_a since_o we_o have_v mention_v the_o prime_n general_n and_o fundamental_a effect_n upon_o which_o
all_o such_o do_v depend_v and_o that_o the_o particular_a enumeration_n of_o its_o effect_n in_o disease_n belong_v to_o its_o curative_fw-it and_o paliative_fw-it virtue_n which_o will_v be_v handle_v hereafter_o the_o rare_a effect_n of_o opium_n take_v in_o a_o moderate_a do_v 1._o temporary_a palsy_n as_o of_o the_o bladder_n and_o sometime_o of_o other_o part_n though_o very_o rare_o 2._o falter_v of_o the_o tongue_n 3._o looseness_n of_o the_o low_a jaw_n as_o in_o the_o drowsy_a drunkard_n etc._n etc._n 4._o prevention_n of_o sweat_n in_o such_o as_o sweat_v too_o much_o for_o want_v of_o perspiration_n 5._o abortion_n 6._o prevention_n of_o abortion_n in_o some_o case_n 7._o intumescence_n of_o the_o li_n 8._o cure_v of_o the_o dropsy_n of_o which_o dr._n willis_n give_v a_o instance_n 9_o cure_v of_o stupor_n of_o some_o sort_n as_o those_o from_o cold_n etc._n etc._n 10._o anxiety_n and_o distress_n 11._o vomit_n and_o hiccough_n 12._o convulsion_n 13._o syncopes_fw-la leipothimy_n and_o faint_n 14._o death_n though_o very_o rare_o and_o that_o in_o very_o weak_a people_n 15._o purge_v 16._o raise_v and_o revive_v some_o person_n that_o be_v just_a expire_a 17._o a_o long_a stay_n thereof_o at_o stomach_n sometime_o 18._o stoppage_n of_o urine_n 19_o it_o sometime_o prove_v dangerous_a after_o hemorrhage_n and_o large_a evacuation_n 1._o note_v that_o the_o first_o class_n of_o effect_n be_v the_o most_o constant_a be_v the_o most_o proper_a genuine_a and_o principal_a effect_n upon_o which_o all_o other_o effect_n depend_v unless_o they_o be_v accidental_a it_o must_v therefore_o be_v that_o these_o shall_v best_a guide_v we_o in_o the_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n 2._o note_v that_o the_o second_o class_n though_o not_o so_o constant_a be_v natural_a effect_n of_o opium_n and_o will_v be_v also_o good_a guide_n for_o the_o same_o purpose_n 3._o note_v that_o there_o be_v but_o little_a notice_n to_o be_v take_v of_o the_o rare_a effect_n for_o that_o purpose_n because_o most_o accidental_a the_o effect_n of_o the_o go_v off_o or_o declination_n of_o the_o operation_n of_o opium_n take_v internal_o in_o a_o moderate_a do_v 1._o a_o general_a return_n of_o all_o the_o disease_n and_o disaster_n that_o opium_n paliate_v during_o its_o operation_n unless_o it_o happen_v that_o some_o be_v cure_v thereby_o which_o iâ—_n they_o be_v be_v general_o by_o the_o benefit_n of_o sweat_n or_o insensible_a perspiration_n as_o cold_n pain_n from_o wind_n or_o humour_n that_o shall_v have_v pass_v by_o the_o pore_n as_o in_o cough_n toothache_n etc._n etc._n from_o construction_n of_o the_o pore_n or_o by_o compose_v the_o fury_n of_o the_o spirit_n or_o blood_n which_o it_o very_o often_o yea_o general_o cure_v with_o one_o single_a do_v but_o of_o these_o thing_n more_o in_o the_o curative_fw-it part._n 2._o sweat_v though_o not_o constant_o 3._o frequent_v make_v of_o water_n sometime_o 4._o a_o looseness_n sometime_o even_o when_o there_o be_v none_o before_o the_o give_v of_o the_o opium_n 5._o disease_n seem_v worse_a than_o before_o the_o take_n of_o it_o 6._o a_o melancholy_a and_o sad_a depression_n of_o spirit_n 7._o a_o narrow_a pulse_n 8._o itch_a of_o the_o skin_n chap._n v._o the_o effect_n of_o opium_n take_v in_o a_o excessive_a quantity_n 1._o a_o heat_n at_o stomach_n 2._o a_o sense_n of_o weight_n at_o stomach_n sometime_o 3._o gaity_n of_o humour_n at_o first_o aâ—_n after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 4._o sardonick_a laughter_n afterward_o as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 5._o laxity_n and_o debility_n of_o all_o part_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 6._o alienation_n of_o the_o mind_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 7._o loss_n of_o memory_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 8._o darkness_n of_o the_o eye_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 9_o laxity_n of_o the_o cornea_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 10._o appearance_n of_o divers_a colour_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 11._o deadness_n of_o the_o eye_n to_o the_o view_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 12._o falter_v of_o the_o tongue_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 13._o a_o sopor_fw-la as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 14._o a_o slow_a and_o wide_a pulse_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 15._o a_o high_a colour_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 16._o looseness_n of_o the_o jaw_n and_o li_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 17._o intumescence_n of_o the_o li_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 18._o difficulty_n of_o breathe_v as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 19_o fury_n and_o madness_n as_o after_o drink_v a_o great_a quantity_n of_o wine_n in_o a_o short_a time_n 20._o venereal_a fury_n 21._o priapism_n 22._o violent_a itch_n 23._o nausea_n 24._o swimmings_n in_o the_o head_n 25._o vertigo_n 26._o vomit_n 27._o hiccough_n 28._o a_o turbulent_a pulse_n 29._o convulsion_n and_o cold_a sweat_v 30._o faint_n and_o leipothymy_n 31._o cold_a breath_n 32._o death_n such_o as_o escape_v it_o general_o have_v 33._o plentiful_a purge_v 34._o sweat_v that_o smell_n of_o the_o opium_n 35._o violent_a itch_n in_o the_o skin_n 1._o note_v that_o all_o these_o effect_n do_v not_o happen_v to_o all_o but_o some_o to_o one_o and_o some_o to_o other_o 2._o that_o these_o effect_n be_v great_a or_o less_o according_a to_o the_o do_v constitution_n of_o the_o person_n and_o other_o circumstance_n 3._o that_o they_o be_v most_o endanger_v thereby_o that_o have_v a_o lax_n and_o fine_a texture_n and_o a_o weak_a digestion_n 4._o that_o a_o looseness_n upon_o it_o be_v a_o good_a sign_n 5._o that_o it_o affect_v some_o by_o make_v they_o furious_a as_o wine_n do_v and_o other_o stupid_a general_o the_o furious_a be_v most_o safe_a from_o danger_n of_o death_n but_o of_o these_o thing_n more_o hereafter_o by_o god_n help_n chap._n vi_o the_o effect_n of_o a_o long_a and_o lavish_a use_n of_o crude_a opium_n 1._o relaxation_n and_o weakness_n of_o all_o part_n 2._o inhability_n or_o listlesness_n to_o do_v any_o thing_n except_o it_o be_v while_o the_o opium_n operate_v 3._o inhability_n or_o listlesness_n to_o get_v up_o in_o the_o morning_n 4._o a_o dull_a moapish_a and_o heavy_a disposition_n as_o in_o old_a drunkard_n except_o it_o be_v during_o the_o operation_n of_o opium_n 5._o diminution_n of_o appetite_n as_o be_v observable_a in_o old_a drunkard_n 6._o weakness_n of_o digestion_n as_o be_v observable_a in_o old_a drunkard_n 7._o dropsy_n as_o be_v observable_a in_o old_a drunkard_n 8._o decay_n of_o part_n as_o be_v observable_a in_o old_a drunkard_n 9_o weakness_n of_o memory_n as_o be_v observable_a in_o old_a drunkard_n 10._o stoop_v in_o the_o back_n as_o be_v observable_a in_o old_a drunkard_n 11._o early_o decrepiteness_n as_o be_v observable_a in_o old_a drunkard_n 12._o shortness_n of_o life_n as_o be_v observable_a in_o old_a drunkard_n 13._o acrimony_n of_o blood_n 14._o inclination_n to_o venery_n 15._o frequent_a inclination_n to_o make_v water_n 16._o priapism_n and_o frequent_a erection_n 17._o nocturnal_a pollution_n the_o effect_n of_o sudden_a leave_v off_o the_o use_n of_o opium_n after_o a_o long_a and_o lavish_a use_v thereof_o 1._o great_a and_o even_o intolerable_a distress_n anxiety_n and_o depression_n of_o spirit_n which_o in_o few_o day_n common_o end_v in_o a_o most_o miserable_a death_n attend_v with_o strange_a agony_n unless_o man_n return_v to_o the_o use_v of_o opium_n which_o soon_o raise_v they_o again_o and_o certain_o restore_v they_o if_o it_o have_v time_n to_o operate_v before_o they_o die_v which_o it_o soon_o do_v in_o a_o liquid_a form_n or_o if_o they_o have_v not_o opium_n or_o will_v not_o take_v it_o they_o must_v use_v wine_n very_o plentiful_o and_o often_o as_o a_o substitute_n to_o the_o opium_n though_o it_o do_v not_o perform_v half_a as_o well_o as_o opium_n 2._o a_o return_n of_o all_o disease_n pain_n and_o disaster_n that_o be_v palliate_v by_o the_o take_n of_o opium_n 3._o dangerous_a looseness_n 4._o death_n follow_v the_o leave_v it_o off_o after_o
as_o to_o the_o nose_n and_o eye_n for_o though_o some_o of_o my_o reader_n may_v not_o easy_o conceive_v it_o the_o representation_n of_o thing_n may_v have_v be_v convey_v by_o reflection_n and_o refraction_n of_o light_n without_o exclude_v the_o air_n but_o that_o it_o be_v more_o convenient_a and_o safe_a for_o the_o brain_n and_o optic_a nerve_n which_o be_v much_o the_o same_o matter_n with_o the_o brain_n and_o a_o production_n thereof_o that_o the_o air_n shall_v be_v exclude_v 6._o notwithstanding_o all_o this_o care_n to_o exclude_v extraneous_a particle_n how_o fine_a soever_o we_o do_v find_v that_o those_o very_a impulse_n convey_v by_o the_o animal_n spirit_n themselves_o in_o the_o most_o gentle_a manner_n imaginable_a do_v often_o offend_v the_o brain_n now_o fair_o consider_v the_o great_a excellency_n and_o use_v of_o the_o brain_n viz._n to_o separate_v the_o animal_n spirit_n to_o accommodate_v the_o soul_n with_o a_o fit_a seat_n for_o it_o its_o tenderness_n and_o softness_n to_o be_v next_o to_o liquidity_n how_o careful_o it_o be_v guard_v with_o about_o nine_o or_o ten_o circumvallation_n or_o considerable_a integument_n that_o those_o we_o common_o call_v organ_n of_o sensation_n be_v contrive_v for_o shutter_n out_o or_o excluder_n of_o the_o least_o extraneous_a particle_n effluvia_n or_o aura_n that_o the_o least_o fume_v that_o rise_v from_o any_o part_n and_o arrive_v at_o the_o brain_n cause_v such_o terrible_a and_o dismal_a effect_n and_o that_o most_o gentle_a touch_n of_o the_o animal_n spirit_n do_v offend_v it_o so_o as_o to_o cause_v tragical_a event_n as_o hysterick_a fit_n vertigo_n &c._n &c._n be_v it_o likely_a that_o notwithstanding_o the_o considerableness_n tenderness_n use_v and_o excellency_n of_o the_o brain_n the_o extraordinary_a providence_n use_v in_o guard_v it_o from_o effluvia_n or_o extraneous_a particle_n how_o fine_a soever_o and_o the_o apparent_a mischief_n that_o the_o least_o fume_v nay_o bare_a impulse_n present_v by_o the_o animal_n spirit_n do_v cause_n that_o the_o same_o providence_n that_o so_o guard_v it_o which_o do_v nothing_o in_o vain_a shall_v after_o all_o its_o care_n and_o nice_a circumspection_n to_o exclude_v the_o least_o fume_v etc._n etc._n permit_v and_o free_o let_v loose_v upon_o it_o and_o into_o it_o whole_a and_o even_o continual_a gust_n blast_n and_o vulcano_n of_o acid_n acrimonious_a putrid_a hot_a stink_a corrosive_a fume_n vapour_n and_o steam_n arise_v from_o glut_a debauch_a and_o surfeit_v stomach_n contain_v all_o imaginable_a trash_n hodgepodge_n vermine_n choler_n etc._n etc._n sure_a it_o be_v much_o fit_a quite_o to_o discharge_v and_o rid_v nature_n of_o they_o at_o mouth_n or_o rather_o send_v they_o downward_o with_o their_o fit_a companion_n the_o stink_a ordure_n and_o excrement_n than_o prefer_v they_o to_o the_o high_a and_o noble_a part_n of_o the_o animal_n and_o sacred_a mansion_n of_o the_o soul_n for_o if_o there_o be_v so_o ready_a free_a open_a and_o constant_a a_o passage_n sensible_a or_o insensible_a for_o the_o fume_n of_o opium_n which_o never_o fail_v of_o its_o effect_n then_o certain_o must_v the_o passage_n be_v alike_o free_a to_o all_o other_o fume_n from_o the_o stomach_n see_v they_o be_v so_o to_o those_o gross_a venomous_a and_o pernicious_a fume_n of_o opium_n as_o willis_n and_o most_o of_o the_o modern_a and_o ancient_a physician_n do_v state_n they_o to_o be_v then_o farewell_n soul_n brain_n life_n and_o all_o for_o it_o be_v not_o conceivable_a that_o the_o man_n can_v hold_v out_o one_o houâ—_n under_o such_o horrid_a and_o dismal_a circumstance_n and_o dreadful_a eructation_n of_o rude_a and_o crude_a fume_n who_o can_v not_o bear_v the_o arrival_n of_o the_o least_o vapour_n scarce_o sensible_a in_o quantity_n or_o quality_n arise_v from_o any_o other_o part_n or_o be_v it_o a_o peculiar_a privilege_n that_o the_o stomach_n have_v thus_o to_o send_v fart_n with_o their_o heel_n upward_o as_o belch_a be_v call_v without_o any_o offence_n to_o perfume_v the_o soul_n presence-chamber_n save_v your_o presence_n however_o foh_o for_o shame_n what_o sort_n of_o opinion_n be_v these_o what_o thick_a stink_a and_o dark_a cloud_n scotomy_n and_o stupor_n must_v the_o opiniator_n be_v under_o by_o their_o own_o consent_n 7._o if_o this_o be_v the_o case_n no_o part_n in_o the_o whole_a body_n will_v be_v in_o such_o a_o miserable_a state_n as_o the_o chief_a for_o the_o rectum_fw-la or_o colon_n be_v fit_v and_o fortify_v by_o nature_n to_o bear_v such_o thing_n so_o be_v not_o the_o tender_a brain_n 8._o what_o horse_n brain_n much_o less_o humane_a one_o can_v bear_v incessant_a raking_n penetration_n stuff_n of_o such_o unnatural_a indigested_a heterogeneous_a rugged_a acid_a acrimonious_a putrid_a and_o impetuous_a fume_n if_o gutta_n cavat_fw-la lapidem_fw-la non_fw-la vi_fw-la sed_fw-la saepe_fw-la cadendo_fw-la what_o will_v become_v of_o the_o tender_a brain_n thus_o â—udely_o rub_v and_o grate_v all_o the_o day_n of_o our_o life_n if_o it_o can_v hold_v out_o any_o for_o it_o be_v incredible_a it_o shall_v 9_o how_o will_v the_o pore_n of_o that_o soft_a substance_n which_o have_v no_o less_o office_n as_o it_o be_v universal_o receive_v than_o to_o separate_v animal_n spirit_n which_o be_v or_o shall_v be_v the_o fine_a and_o most_o subtle_a tenuious_a and_o principal_a thing_n in_o a_o animal_n next_o the_o soul_n itself_o be_v discompose_v tear_v dilate_a stuff_v what_o a_o bless_a sâ—retion_n of_o animal_n spirit_n if_o any_o will_v there_o be_v 10._o it_o be_v observe_v by_o all_o that_o the_o brain_n though_o very_o soft_a receive_v the_o least_o change_n of_o any_o part_n of_o the_o body_n which_o can_v never_o be_v consider_v its_o tenderness_n if_o it_o be_v so_o rake_v by_o all_o sort_n of_o fume_n for_o then_o doubtless_o such_o a_o body_n will_v be_v most_o change_v of_o any_o in_o colour_n substance_n texture_n bigness_n etc._n etc._n what_o will_v become_v of_o memory_n and_o indeed_o of_o all_o the_o faculty_n of_o the_o brain_n can_v a_o soft_a yield_a substance_n continual_o discompose_v preserve_v impression_n make_v thereon_o if_o fume_n flow_v continual_o through_o the_o brain_n they_o must_v wear_v out_o all_o impression_n yea_o and_o the_o brain_n itself_o in_o a_o short_a time_n 11._o it_o will_v be_v very_o dangerous_a to_o eat_v or_o drink_v if_o the_o brain_n must_v suffer_v so_o much_o by_o the_o fume_n of_o meat_n wine_n etc._n etc._n it_o will_v be_v hard_a to_o know_v whether_o it_o be_v best_a to_o eat_v or_o not_o for_o both_o must_v be_v fatal_a 12._o what_o a_o vast_a difference_n shall_v we_o observe_v as_o to_o serenity_n of_o mind_n etc._n etc._n when_o empty_a and_o full_a for_o in_o this_o last_o case_n the_o brain_n must_v be_v all_o in_o a_o cloud_n or_o a_o cloud_n in_o it_o or_o both_o yet_o be_v man_n much_o more_o serenâ—_n prompt_v and_o fit_a for_o any_o thing_n after_o some_o glass_n of_o wine_n than_o before_o and_o after_o moderate_a eat_v than_o when_o hungry_a which_o make_v they_o faint_a peevish_a ill-humoured_a and_o listless_a 13._o if_o the_o vapour_n or_o fume_n of_o opium_n fly_v up_o to_o the_o brain_n cause_v all_o its_o effect_n it_o be_v very_o strange_a that_o our_o fumi_fw-la venduli_fw-la have_v not_o long_o since_o find_v out_o the_o mountebank_n gambol_n of_o stand_v upon_o their_o head_n to_o prevent_v all_o mischief_n from_o opium_n take_v in_o a_o great_a do_v for_o fume_n in_o a_o warm_a live_a body_n will_v not_o descend_v into_o the_o head_n i_o wonder_v they_o do_v not_o find_v out_o such_o a_o easy_a and_o natural_a consequence_n of_o their_o hypothesis_n if_o true_a they_o may_v then_o have_v bold_o mount_v any_o stage_n free_o take_v opium_n in_o the_o sight_n of_o the_o admire_a rabble_n their_o summerset_n go_v upon_o their_o hand_n etc._n etc._n will_v have_v secure_v they_o and_o turn_v danger_n topsie-turvy_o by_o the_o help_n of_o a_o comical_a gesture_n this_o be_v indeed_o somewhat_o to_o purpose_n if_o it_o succeed_v if_o not_o i_o shall_v think_v it_o be_v enough_o to_o ridicule_n their_o hypothesis_n out_o of_o all_o credit_n without_o any_o far_a argument_n i_o dare_v join_v issue_n with_o they_o upon_o that_o point_n that_o it_o will_v not_o succeed_v though_o a_o necessary_a consequence_n of_o their_o opinion_n if_o true_a wherein_o they_o will_v have_v this_o advantage_n that_o they_o will_v confess_v with_o one_o that_o never_o do_v or_o will_v try_v it_o as_o be_v well_o assure_v of_o the_o falsity_n of_o both_o the_o hypothesis_n and_o the_o experiment_n without_o such_o a_o trial_n of_o skill_n now_o i_o think_v that_o i_o have_v say_v enough_o and_o will_v willing_o give_v over_o argue_v and_o spend_v any_o more_o time_n to_o confute_v a_o hypothesis_n so_o absurd_a that_o it_o must_v needs_o appear_v so_o to_o
impossible_a it_o shall_v be_v without_o such_o disturbance_n as_o i_o mention_v will_v follow_v if_o they_o pass_v in_o the_o road_n of_o the_o spirit_n it_o be_v not_o common_a sense_n that_o such_o câ—de_a blast_n shall_v meliorate_v or_o enliven_v the_o spirit_n to_o cause_v briskness_n bravery_n serenity_n courage_n magnanimity_n as_o opium_n do_v much_o less_o if_o those_o fume_n stop_v and_o crowd_v in_o the_o brain_n and_o any_o way_n hinder_v the_o generation_n of_o animal_n spirit_n as_o the_o common_a assertion_n be_v the_o like_a be_v to_o be_v say_v of_o their_o pass_v between_o the_o pia_fw-la mater_fw-la and_o the_o medullary_a part_n of_o the_o nerve_n which_o can_v be_v allow_v because_o of_o its_o close_a adherence_n thereto_o with_o this_o addition_n that_o they_o will_v constant_o cause_v a_o violent_a headache_n which_o opium_n and_o meal_n to_o which_o fume_n be_v particular_o attribute_v do_v often_o cure_v so_o if_o they_o get_v up_o to_o the_o head_n between_o the_o pia_n and_o dura_n mater_n it_o be_v headache_n and_o not_o the_o symptom_n of_o opium_n that_o they_o will_v produce_v which_o headache_n as_o be_v say_v opium_n and_o meal_n do_v cure_v 21._o last_o if_o they_o pass_v by_o any_o mean_n quite_o on_o the_o outside_n of_o the_o nerve_n and_o their_o membrane_n viz._n the_o pia_n and_o dura_n mater_n then_o must_v they_o take_v their_o lodgement_n if_o within_o the_o skull_n between_o the_o dura_n mater_n and_o the_o skull_n and_o produce_v no_o other_o symptom_n but_o a_o headache_n which_o as_o be_v say_v opium_n and_o meal_n rather_o cure_v than_o produce_v and_o if_o without_o the_o skull_n it_o be_v quite_o beside_o the_o cushion_n and_o the_o vaporarian_n own_o intention_n for_o in_o all_o these_o last_o case_n they_o can_v not_o affect_v the_o animal_n spirit_n for_o good_a or_o evil_n many_o and_o very_o many_o thing_n may_v be_v add_v to_o show_v the_o impossibility_n inconvenience_n incoherence_n absurdity_n etc._n etc._n that_o attend_v the_o passage_n of_o the_o fume_n and_o vapour_n into_o the_o brain_n head_n etc._n etc._n 22._o i_o have_v forgotâ—_n mention_v the_o absurdity_n of_o its_o pass_v up_o at_o gullet_n and_o so_o to_o the_o head_n because_o i_o can_v not_o imagine_v that_o any_o one_o will_v be_v so_o beastly_a a_o animal_n as_o to_o belch_v up_o a_o argument_n of_o that_o kind_n consider_v our_o very_a sense_n tell_v we_o that_o what_o come_v up_o that_o way_n pass_v out_o at_o mouth_n or_o nostril_n and_o because_o if_o it_o be_v so_o the_o operation_n of_o opium_n etc._n etc._n will_v be_v in_o proportion_n to_o our_o belch_a which_o be_v ridiculous_a 23._o the_o great_a comfort_n of_o a_o cordial_n be_v at_o first_o or_o soon_o after_o it_o be_v take_v but_o if_o '_o its_o comfort_n be_v by_o fume_n or_o essluvia_n pass_v to_o the_o blood_n or_o any_o where_o beside_o the_o comfort_n will_v as_o their_o cause_n of_o fume_n do_v increase_v for_o a_o long_a time_n and_o be_v more_o after_o a_o good_a while_n than_o at_o first_o so_o 24._o if_o opium_n operate_v by_o fume_n while_o at_o stomach_n which_o must_v gradual_o increase_v continual_o how_o come_v opium_n to_o be_v at_o the_o height_n of_o its_o operation_n in_o a_o short_a time_n viz._n in_o about_o half_a a_o hour_n after_o it_o begin_v sensible_o to_o operate_v or_o a_o hour_n at_o far_a and_o not_o increase_v continual_o in_o its_o operation_n as_o their_o pretend_a cause_n the_o fume_n must_v do_v by_o continual_a steam_a 25._o if_o opium_n operate_v by_o send_v fume_n by_o passage_n etc._n etc._n from_o the_o stomach_n to_o the_o brain_n i_o shall_v think_v that_o when_o it_o have_v get_v out_o of_o the_o stomach_n as_o into_o the_o intestine_n lacteal_v vein_n etc._n etc._n there_o shall_v be_v a_o kind_n of_o interval_n of_o its_o operation_n which_o be_v never_o observe_v till_o it_o get_v into_o the_o blood_n again_o therefore_o it_o do_v not_o operate_v by_o fume_n for_o the_o pylorus_n be_v always_o shut_v but_o when_o somewhat_o be_v send_v downward_o which_o will_v hinder_v the_o mount_a of_o the_o vapour_n into_o the_o stomach_n in_o order_n to_o pass_v to_o the_o brain_n 26._o if_o vapour_n be_v the_o cause_n of_o sleep_n after_o meal_n than_o shall_v we_o be_v more_o sleepy_a two_o or_o three_o hour_n after_o meal_n because_o of_o the_o abundance_n of_o the_o fume_n that_o will_v be_v crowd_v into_o the_o brain_n by_o that_o time_n but_o we_o be_v more_o sleepy_a present_o after_o meal_n and_o if_o we_o indulge_v it_o but_o for_o a_o quarter_n of_o a_o hour_n we_o be_v refresh_v and_o far_o from_o sleepiness_n afterward_o though_o the_o fume_n if_o that_o hypothesis_n be_v true_a will_v be_v much_o more_o at_o brain_n two_o or_o three_o hour_n after_o the_o meal_n so_o it_o be_v in_o the_o case_n of_o wine_n if_o one_o take_v a_o short_a nap_n after_o some_o glass_n he_o may_v drink_v a_o great_a many_o afterward_o without_o be_v sleepy_a which_o plain_o prove_v that_o it_o be_v not_o the_o fume_n of_o the_o wine_n be_v the_o cause_n of_o the_o sleep_n because_o he_o be_v not_o at_o all_o sleepy_a when_o there_o must_v be_v more_o fume_n 27._o all_o allow_v that_o hot_a fume_n assault_v the_o brain_n cause_n frenzy_n if_o that_o be_v true_a than_o the_o fume_n of_o wine_n and_o opium_n which_o be_v both_o very_a hot_a must_v always_o do_v so_o but_o opium_n and_o wine_n also_o do_v often_o cause_v composure_n good_a humour_n sleep_v etc._n etc._n which_o be_v contrary_a to_o frenzy_n therefore_o they_o do_v not_o operate_v by_o fume_n 28._o if_o sleep_n say_v helmont_n the_o only_a man_n that_o i_o have_v read_v who_o be_v against_o vapour_n be_v cause_v by_o vapour_n ascend_v from_o the_o stomach_n to_o the_o head_n obstruct_v and_o intercept_n all_o the_o passage_n of_o sensation_n motion_n speech_n judgement_n etc._n etc._n as_o the_o school_n say_v than_o a_o disease_n will_v have_v be_v before_o the_o fall_n of_o adam_n because_o sleep_n will_v have_v be_v a_o disease_n that_o be_v a_o flatulent_a and_o vaporous_a palsy_n 29._o all_o allow_v vomitives_n and_o purger_n to_o operate_v by_o irritation_n or_o a_o grievous_a sensation_n of_o the_o membrane_n of_o the_o stomach_n why_o not_o wine_n cordial_n opium_n etc._n etc._n by_o a_o pleasant_a sensation_n cujus_fw-la est_fw-la dolour_n aut_fw-la gravamen_fw-la ejusdem_fw-la est_fw-la voluptas_fw-la and_o as_o a_o grievous_a sensation_n or_o pain_n cause_v melancholy_a depression_n of_o spirit_n fretfulness_n lassitude_n etc._n etc._n so_o a_o pleasant_a sensation_n cause_v comfort_n elevation_n of_o the_o spirit_n euphory_n etc._n etc._n but_o we_o have_v not_o clear_v the_o way_n sufficient_o for_o these_o matter_n yet_o which_o will_v in_o due_a time_n be_v solemn_o consider_v obj._n it_o may_v be_v say_v that_o both_o vomitives_n and_o purgative_n take_v some_o time_n before_o they_o operate_v unless_o a_o nausea_n upon_o aversion_n cause_v they_o to_o work_v soon_o for_o thing_n must_v have_v time_n to_o insinuate_v themselves_o or_o soak_v through_o the_o crusta_fw-la carnosa_fw-la of_o the_o stomach_n and_o afterward_o to_o affect_v its_o sensile_a coat_n which_o argue_v that_o wine_n and_o cordial_n which_o operate_v immediate_o do_v not_o operate_v that_o way_n but_o by_o fume_n or_o effuvium_n pass_v into_o the_o brain_n or_o blood_n answ._n i_o doubt_v indeed_o that_o this_o difference_n may_v be_v a_o occasion_n of_o refer_v the_o effect_n of_o cordial_n and_o those_o of_o emittick_n and_o cathartic_o to_o different_a cause_n but_o it_o be_v very_o strange_a that_o they_o shall_v go_v so_o far_o as_o the_o blood_n or_o brain_n to_o seek_v for_o the_o cause_n of_o the_o operation_n of_o cordial_n which_o operate_v in_o a_o moment_n and_o go_v no_o far_o than_o the_o stomach_n for_o the_o cause_n of_o the_o operation_n of_o vomatives_n and_o purgative_n which_o take_v more_o time_n to_o operate_v especial_o see_v the_o blood_n and_o brain_n have_v no_o sensation_n and_o that_o all_o sensitive_a comfort_n happen_v by_o that_o mean_n i_o think_v it_o be_v much_o more_o proper_a first_o to_o consider_v the_o immediate_a part_n upon_o which_o they_o insist_v when_o at_o stomach_n especial_o see_v it_o be_v so_o very_o sensible_a before_o we_o run_v rove_a i_o know_v not_o whither_o to_o seek_v for_o the_o cause_n of_o a_o thing_n that_o work_v please_v and_o comfort_v the_o stomach_n as_o soon_o as_o it_o be_v down_o i_o take_v myself_o run_v off_o the_o proper_a subject_a matter_n of_o this_o chapter_n and_o anticipate_v that_o of_o another_o therefore_o i_o will_v be_v short_a and_o deliver_v my_o opinion_n in_o this_o case_n by_o way_n of_o position_n with_o a_o familiar_a instance_n to_o illustrate_v it_o which_o may_v in_o some_o measure_n prepare_v you_o for_o the_o proof_n
the_o spirit_n by_o any_o mean_n for_o there_o be_v nothing_o so_o good_a in_o nature_n but_o will_v do_v it_o if_o use_v undue_o or_o immoderate_o as_o wine_n bread_n milk_n honey_n sugar_n beer_n etc._n etc._n in_o excess_n for_o i_o intend_v that_o it_o do_v not_o do_v it_o when_o due_o and_o moderate_o use_v 1._o that_o which_o refresh_v the_o weary_a and_o high_o prevent_v weariness_n must_v add_v to_o or_o excite_v the_o spirit_n which_o be_v direct_o contrary_a to_o diminish_v or_o disable_n they_o but_o opium_n do_v in_o a_o most_o eminent_a manner_n refresh_v the_o weary_v and_o prevent_v weariness_n therefore_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n some_o have_v be_v so_o silly_a and_o inadvertent_n as_o to_o object_n that_o it_o refresh_v the_o weary_a only_o by_o sleep_n it_o be_v matter_n of_o fact_n that_o it_o refresh_v they_o whether_o they_o sleep_v or_o no_o and_o that_o without_o fail_v as_o often_o as_o it_o be_v use_v in_o that_o case_n other_o that_o be_v no_o wise_a have_v say_v that_o it_o only_o take_v off_o the_o sense_n of_o weariness_n by_o stupify_a which_o happen_v by_o the_o diminish_n or_o disable_n of_o the_o animal_n spirit_n bare_a insensibleness_n can_v enable_v the_o spirit_n to_o labour_n with_o eminent_a briskness_n and_o alacrity_n as_o man_n most_o certain_o do_v after_o opium_n be_v take_v be_v fine_o enliven_v and_o invigorate_v as_o with_o generous_a wine_n if_o they_o do_v not_o know_v this_o to_o be_v true_a let_v they_o for_o shame_n hold_v their_o tongue_n till_o they_o know_v matter_n of_o fact_n which_o if_o they_o will_v not_o they_o proclaim_v themselves_o to_o be_v idle_a and_o impertinent_a babbler_n but_o if_o they_o will_v patient_o and_o wise_o abstain_v argue_v till_o they_o be_v satisfy_v as_o to_o matter_n of_o fact_n then_o will_v they_o be_v past_a opinion_n and_o hypothesis_n in_o that_o case_n for_o they_o will_v have_v sensible_a and_o certain_a knowledge_n of_o the_o contrary_a and_o the_o truth_n of_o what_o i_o say_v which_o will_v end_v all_o controversy_n and_o precarious_a squabble_n upon_o false_a supposition_n as_o the_o manner_n be_v that_o can_v lead_v they_o to_o what_o be_v right_o but_o by_o mere_a chance_n and_o never_o to_o a_o true_a knowledge_n that_o they_o be_v in_o the_o right_n which_o make_v it_o none_o in_o effect_n for_o they_o can_v do_v nothing_o with_o assurance_n but_o only_o suppose_v and_o hope_v they_o be_v in_o the_o right_n when_o they_o be_v as_o much_o out_o to_o their_o patient_n sorrow_n as_o physician_n have_v be_v in_o the_o cold_a quality_n and_o fume_n of_o opium_n it_o be_v true_a that_o a_o grain_n or_o two_o of_o opium_n will_n if_o a_o man_n compose_v himself_o sit_v or_o lie_v still_o cause_n a_o sleepiness_n equal_a to_o that_o cause_v by_o spend_v the_o spirit_n by_o a_o day_n be_v labour_n but_o spend_v of_o the_o spirit_n be_v not_o the_o only_a no_o nor_o best_a proportion_v or_o more_o adequate_a cause_n thereof_o as_o i_o have_v show_v if_o loss_n of_o spirit_n be_v the_o adequate_a cause_n of_o sleep_n how_o shall_v good_a and_o generous_a wine_n cause_n sleepiness_n after_o that_o eminent_a rate_n as_o it_o do_v in_o most_o people_n how_o shall_v the_o most_o please_a music_n incline_v such_o as_o lie_v or_o sit_v still_o to_o sleep_v but_o if_o one_o dance_n thereto_o it_o make_v he_o more_o lively_a and_o brisk_a than_o ordinary_a the_o like_a exact_o do_v wine_n and_o opium_n if_o man_n lie_v or_o sit_v still_o but_o otherwise_o they_o make_v they_o much_o more_o brisk_a and_o lively_a and_o able_a to_o undergo_v labour_n action_n etc._n etc._n which_o note_n that_o you_o may_v not_o any_o more_o wonder_n that_o enlivener_n and_o exciter_n of_o the_o spirit_n do_v cause_n sleep_v as_o well_o as_o diminisher_n thereof_o and_o observe_v that_o they_o be_v all_o please_a thing_n as_o music_n wine_n and_o opium_n which_o cause_n pleasant_a dream_n pleasant_a watch_n pleasant_a humour_n etc._n etc._n expect_v more_o of_o this_o matter_n in_o the_o follow_a chapter_n and_o all_o by_o degree_n according_a as_o i_o judge_v the_o prejudice_v world_n will_v bear_v thing_n for_o a_o great_a paradox_n how_o true_a soever_o must_v not_o be_v abrupt_o obtrude_v but_o gentle_o and_o gradual_o usher_v in_o by_o insinuate_v reason_v otherwise_o it_o will_v be_v entertain_v like_o a_o rude_a stranger_n that_o contradict_v a_o multitude_n in_o fashion_n and_o custom_n that_o they_o have_v always_o use_v and_o judge_v to_o be_v the_o very_o best_o however_o unblamable_a consider_v that_o if_o opium_n diminish_v or_o disable_v the_o spirit_n proportionable_a to_o the_o sleepiness_n that_o it_o cause_n as_o a_o hard_a day_n be_v labour_n do_v then_o if_o opium_n be_v give_v a_o man_n after_o a_o hard_a day_n be_v labour_n it_o will_v be_v as_o it_o be_v add_v another_o hard_a day_n be_v labour_v to_o cure_v it_o the_o day_n be_v labour_n and_o opium_n impair_n the_o spirit_n alike_o think_v what_o a_o miserable_a condition_n the_o poor_a man_n will_v be_v in_o especial_o if_o sleep_n do_v not_o make_v he_o some_o amends_o it_o will_v be_v such_o as_o be_v utter_o intolerable_a but_o so_o far_o be_v opium_n from_o any_o such_o effect_n that_o it_o refresh_v he_o though_o he_o sleep_v not_o at_o all_o after_o the_o hard_a day_n be_v labour_n and_o not_o only_o so_o but_o will_v enable_v he_o to_o work_v all_o the_o follow_a night_n with_o great_a alacrity_n if_o need_n require_v it_o what_o a_o condition_n will_v those_o be_v in_o who_o take_v a_o drachm_n of_o it_o twice_o a_o day_n for_o 10_o 20_o or_o 30_o year_n nay_o how_o can_v any_o possible_o do_v it_o for_o half_a 10_o day_n if_o a_o grain_n or_o two_o destroy_v the_o spirit_n so_o much_o as_o to_o cause_v sleepiness_n thereby_o as_o hard_a labour_n do_v which_o they_o must_v allow_v that_o assert_v it_o cause_n sleep_v by_o diminish_v or_o disable_n the_o spirit_n but_o some_o may_v say_v though_o very_o inconsiderate_o that_o it_o only_o disable_v they_o for_o the_o time_n of_o its_o operation_n that_o be_v strange_a indeed_o consider_v that_o even_o during_o that_o time_n they_o be_v most_o enable_v to_o work_n or_o labour_n though_o tire_v before_o and_o that_o it_o 2._o cause_n comfort_n refreshment_n ovation_n of_o the_o spirit_n all_o the_o time_n of_o its_o operation_n as_o wine_n moderate_o take_v do_v especial_o if_o people_n keep_v themselves_o in_o action_n labour_n etc._n etc._n otherwise_o indeed_o they_o may_v fall_v asleep_a upon_o the_o comfortable_a satisfaction_n contentation_n of_o mind_n and_o acquiescence_n of_o spirit_n that_o it_o occasion_n as_o wine_n do_v 3._o the_o first_o effect_n that_o we_o find_v of_o opium_n which_o may_v therefore_o probable_o be_v a_o very_a lead_n fundamental_a and_o significant_a effect_n be_v that_o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o incline_v he_o to_o sleep_n if_o not_o it_o make_v he_o gay_a good_a humour_a brave_a etc._n etc._n it_o be_v a_o pleasure_n so_o sweet_a and_o delicious_a that_o though_o i_o endeavour_v to_o express_v it_o by_o the_o ovation_n of_o the_o spirit_n upon_o joy_n a_o good_a genius_n inform_v a_o man_n or_o the_o helmâ—sians_n archaeus_n in_o his_o best_a humour_n or_o a_o continual_a vâ—real_a pleasure_n wine_n drink_v ad_fw-la hilaritatem_fw-la etc._n etc._n yet_o i_o doubt_v all_o my_o way_n of_o express_v it_o do_v come_v short_a of_o the_o charm_a complacency_n that_o it_o cause_n therefore_o if_o wine_n music_n a_o good_a meal_n agreeable_a frication_n of_o the_o head_n or_o back_o the_o sound_n of_o water_n etc._n etc._n do_v incline_v we_o to_o sleep_v by_o the_o pleasure_n thereof_o which_o lull_v and_o soothe_v we_o to_o it_o as_o be_v most_o certain_a if_o we_o sit_v or_o lie_v still_o much_o more_o must_v the_o high_a charm_n of_o opium_n cause_n it_o that_o it_o be_v a_o pleasure_n that_o affect_v by_o one_o of_o our_o sense_n namely_o by_o feel_v be_v indisputable_a for_o it_o be_v not_o a_o pleasure_n of_o the_o eye_n nose_n tongue_n or_o ear_n and_o it_o must_v be_v sensitive_a because_o cause_v by_o matter_n and_o that_o opium_n have_v doubtless_o the_o like_a effect_n upon_o brute_n who_o have_v no_o other_o pleasure_n but_o what_o be_v sensitive_a that_o it_o be_v at_o stomach_n be_v also_o evident_a where_o we_o can_v be_v please_v only_o by_o the_o sense_n of_o feel_v that_o it_o be_v involuntary_a and_o please_v we_o whether_o we_o will_v or_o no_o and_o that_o the_o same_o particle_n excite_v venery_n itch_a etc._n etc._n now_o all_o the_o sense_n especial_o feel_v and_o particular_o that_o at_o stomach_n be_v give_v we_o for_o
of_o man_n because_o of_o its_o ill_a effect_n lavish_o use_v therefore_o none_o can_v argue_v from_o that_o that_o opium_n diminish_v or_o disable_v the_o spirit_n any_o more_o than_o wine_n or_o bread_n do_v a_o surfeit_n of_o which_o be_v most_o dangerous_a omnis_fw-la repletio_fw-la mala_fw-la panis_n vero_fw-la pessima_fw-la &_o corruptio_fw-la optimi_fw-la est_fw-la pessima_fw-la that_o be_v all_o repletion_n be_v bad_a but_o that_o of_o bread_n be_v the_o worst_a and_o the_o corruption_n of_o the_o best_a be_v the_o worst_a the_o short_a be_v this_o wine_n and_o opium_n agree_v in_o all_o their_o effect_n save_v such_o as_o be_v consequence_n of_o their_o different_a accident_n as_o the_o quantity_n of_o wine_n that_o must_v be_v use_v to_o cause_v the_o same_o effect_n with_o a_o little_a opium_n and_o wine_n have_v be_v ferment_v and_o opium_n as_o may_v be_v show_v have_v some_o crude_a and_o viscid_a rosin_n in_o it_o which_o sometime_o stick_v to_o the_o crusta_fw-la carnosa_fw-la etc._n etc._n of_o the_o stomach_n whence_o it_o happen_v that_o wine_n load_v one_o more_o heat_v more_o and_o be_v more_o troublesome_a upon_o those_o account_n and_o that_o opium_n offend_v the_o stomach_n often_o even_o in_o a_o moderate_a do_v cause_v vomit_n hiccough_n anxiety_n distress_n at_o stomach_n deliquium_n etc._n etc._n because_o of_o the_o indigestible_a rosin_n stick_v to_o the_o side_n of_o the_o most_o sensile_a stomach_n as_o i_o shall_v far_o prove_v hereafter_o by_o god_n help_n show_v very_o easy_a way_n and_o mean_n to_o separate_v that_o rosin_n and_o so_o make_v it_o as_o safe_a and_o less_o troublesome_a as_o it_o be_v more_o effectual_a than_o wine_n opium_n can_v diminish_v or_o disable_v the_o spirit_n because_o as_o have_v be_v prove_v it_o send_v no_o part_n fume_v or_o effluvium_fw-la to_o the_o brain_n or_o animal_n spirit_n to_o cause_v such_o bad_a effect_n while_o it_o be_v at_o stomach_n yet_o do_v it_o produce_v they_o while_o it_o be_v there_o for_o as_o the_o vaporarians_n themselves_o and_o indeed_o all_o man_n allow_v there_o can_v be_v no_o destruction_n without_o contact_n sanctorius_n do_v well_o and_o true_o observe_v by_o the_o help_n of_o his_o static_o that_o nothing_o cause_v liberal_a perspiration_n but_o it_o raise_v the_o spirit_n it_o be_v most_o certain_a that_o nothing_o in_o nature_n open_v the_o pore_n and_o cause_n perspiration_n more_o than_o opium_n therefore_o nothing_o shall_v according_a to_o his_o observation_n elevate_v the_o spirit_n more_o and_z indeed_o nothing_o do_v as_o appear_v by_o all_o that_o have_v be_v say_v and_o will_v yet_o more_o plain_o appear_v loss_n of_o memory_n by_o opium_n as_o some_o argue_v be_v not_o so_o much_o a_o loss_n of_o spirit_n as_o lanity_n of_o the_o brain_n for_o people_n in_o drink_n do_v not_o want_v spirit_n but_o there_o be_v a_o great_a relaxation_n of_o the_o brain_n and_o its_o membrane_n and_o of_o the_o whole_a jenus_fw-la 〈◊〉_d which_o relaxation_n cause_v a_o soft_a loose_a and_o labile_fw-la brain_n that_o like_o liquid_a thing_n retain_v no_o impression_n beside_o that_o i_o shall_v god_n will_v show_v you_o hereafter_o that_o impression_n can_v be_v so_o well_o make_v upon_o the_o sensitive_a soul_n by_o the_o animal_n spirit_n upon_o relaxation_n of_o the_o sensible_a part_n as_o in_o sleep_n etc._n etc._n for_o a_o very_a plain_a mechanical_a reason_n to_o be_v show_v in_o due_a time_n thus_o have_v i_o by_o the_o assistance_n of_o its_o maker_n who_o best_o know_v it_o clear_v opium_n from_o the_o false_a aspersion_n of_o a_o extreme_a cold_a quality_n and_o parcotick_a fume_n both_o which_o be_v common_o call_v venomous_a fatal_a and_o by_o all_o the_o ill_a name_n imaginable_a but_o as_o good_a luck_n be_v they_o abuse_v nothing_o because_o it_o be_v manifest_a that_o there_o be_v no_o such_o thing_n nor_o have_v it_o any_o quality_n by_o which_o it_o diminish_v or_o disable_v the_o spirit_n as_o be_v most_o evident_a from_o the_o premise_n so_o that_o all_o that_o have_v be_v say_v of_o opium_n by_o way_n of_o hypothesis_n to_o explain_v its_o effect_n depend_v upon_o its_o diminish_n or_o disable_n the_o spirit_n by_o a_o cold_a quality_n or_o fume_n be_v come_v to_o nothing_o i_o wish_v it_o have_v be_v as_o innocent_a chap._n xii_o show_v what_o must_v be_v the_o true_a cause_n of_o the_o operation_n of_o opium_n all_o the_o general_a foundation_n upon_o which_o author_n either_o ancient_a or_o modern_a erect_v their_o several_a hypothesise_n concern_v the_o operation_n of_o opium_n have_v as_o manifest_o appear_v no_o real_a existence_n what_o enchant_a castle_n in_o the_o air_n or_o vain_a phantasm_n must_v their_o structure_n be_v and_o how_o like_a delude_a wizzard_n must_v they_o appear_v while_o they_o seem_v to_o take_v high_a flight_n and_o glorious_a prospect_n of_o cause_n that_o have_v no_o reality_n thus_o be_o i_o leave_v utter_o destitute_a of_o either_o foundation_n or_o model_n unless_o i_o find_v out_o that_o and_o frame_v this_o which_o i_o hope_v may_v be_v easy_o do_v because_o the_o cloudy_a supposition_n of_o vapour_n have_v vanish_v away_o there_o now_o remain_v but_o two_o way_n by_o which_o a_o internal_a medicament_n can_v operate_v viz._n 1._o as_o a_o alterative_a of_o the_o blood_n etc._n etc._n or_o 2._o as_o affect_v the_o sense_n of_o feel_v either_o grievous_o as_o vomit_n purger_n etc._n etc._n or_o pleas_o as_o cordial_n generous_a wine_n titillate_v amphrodisiack_n comfortable_a warmth_n anodynes_n and_o such_o like_a that_o please_v the_o nerve_n and_o membrane_n which_o way_n of_o operate_n be_v too_o little_o observe_v by_o physician_n though_o they_o take_v great_a notice_n of_o the_o operation_n of_o thing_n by_o grievous_a sensation_n as_o irritative_n to_o vomit_n purge_v salivate_a etc._n etc._n by_o their_o acrimony_n whereas_o the_o pleaser_n of_o sensation_n which_o must_v as_o contrary_n have_v contrary_a operation_n be_v little_o regard_v or_o think_v of_o 1._o opium_n do_v not_o operate_v as_o a_o alterative_a of_o the_o blood_n etc._n etc._n first_o because_o it_o operate_v while_o it_o be_v at_o stomach_n or_o at_o least_o before_o it_o arrive_v at_o the_o blood_n which_o manifest_o appear_v several_a way_n as_o 1._o because_o it_o often_o operate_v in_o a_o liquid_a form_n in_o few_o minute_n and_o very_o common_o in_o a_o quarter_n of_o a_o hour_n in_o which_o time_n it_o must_v be_v at_o stomach_n or_o at_o least_o far_o from_o arrive_v at_o the_o blood_n 2._o because_o it_o have_v be_v very_o often_o vomit_v up_o after_o it_o have_v operate_v and_o produce_v its_o usual_a effect_n for_o 1_o 2_o 3_o 4_o 5_o 6_o 8_o 10_o and_o sometime_o more_o hour_n as_o evident_o appear_v by_o the_o smell_n colour_n taste_v etc._n etc._n of_o what_o be_v vomit_v and_o by_o its_o operation_n cease_v after_o such_o vomit_v of_o which_o common_a experience_n and_o author_n do_v inform_v we_o see_v helmont_n ius_n duumvir_fw-la 62._o where_o he_o tell_v of_o opium_n operate_a at_o night_n and_o vomit_v up_o next_o morning_n 3._o it_o be_v bare_a cause_v vomit_v after_o it_o have_v operate_v for_o a_o good_a while_n be_v of_o itself_o though_o its_o taste_n smell_v etc._n etc._n do_v not_o discover_v it_o a_o infallible_a argument_n of_o its_o operate_n while_o it_o be_v at_o stomach_n for_o it_o be_v against_o all_o reason_n to_o imagine_v that_o thing_n shall_v irritate_fw-la it_o to_o vomit_n after_o they_o be_v go_v into_o the_o blood_n and_o not_o do_v it_o while_o they_o be_v in_o the_o stomach_n itself_o as_o all_o vomitory_n do_v the_o reason_n why_o it_o stay_v so_o long_o at_o stomach_n be_v 1._o it_o be_v indigestibleness_n which_o plain_o appear_v by_o stool_n urine_n and_o sweat_v smell_v of_o it_o when_o take_v in_o any_o considerable_a quantity_n all_o the_o coction_n digestion_n circulation_n etc._n etc._n that_o it_o pass_v in_o the_o body_n signify_v very_o little_a to_o it_o which_o its_o cause_v itch_n in_o the_o skin_n and_o affect_v the_o venereal_a membrane_n after_o its_o pass_v the_o blood_n do_v also_o argue_v 2._o the_o clamminess_n of_o its_o resinous_a part_n stick_v to_o the_o stomach_n cause_n as_o i_o shall_v plain_o prove_v hereafter_o its_o long_a stay_n in_o it_o for_o if_o the_o rosin_n be_v separate_v from_o it_o it_o will_v not_o then_o make_v such_o a_o long_a stay_n at_o stomach_n as_o i_o have_v often_o experience_v 4._o we_o actual_o feel_v it_o cause_v a_o sense_n of_o pleasure_n at_o stomach_n during_o its_o operation_n therefore_o it_o be_v then_o in_o it_o 5._o it_o have_v be_v carry_v off_o by_o stool_n after_o it_o have_v produce_v its_o usual_a effect_n therefore_o it_o operate_v before_o it_o arrive_v at_o the_o blood_n 6._o all_o observer_n do_v allow_v that_o opium_n operate_v while_o it_o be_v at_o stomach_n
which_o give_v the_o occasion_n as_o you_o may_v remember_v to_o the_o hypothesis_n of_o its_o operate_n by_o fume_n rise_v out_o of_o the_o stomach_n because_o they_o can_v not_o think_v of_o any_o other_o mean_v by_o which_o it_o may_v affect_v the_o head_n brain_n animal_n spirit_n nerve_n etc._n etc._n while_o it_o be_v at_o stomach_n but_o by_o the_o way_n of_o fume_n or_o vapour_n it_o be_v therefore_o past_a all_o doubt_n that_o opium_n produce_v its_o common_a effect_n while_o it_o be_v at_o stomach_n and_o before_o it_o arrive_v at_o the_o blood_n and_o therefore_o do_v not_o operate_v as_o a_o alterative_a thereof_o second_o because_o a_o grain_n of_o opium_n which_o operate_v very_o remarkable_o bear_v as_o etmuller_n well_o observe_v so_o small_a a_o proportion_n to_o the_o blood_n that_o it_o can_v produce_v such_o great_a and_o notable_a effect_n as_o a_o alterative_a thereof_o for_o a_o grain_n of_o opium_n to_o 20_o pound_n of_o blood_n which_o a_o ordinary_a man_n have_v in_o his_o body_n be_v but_o as_o 1_o to_o 115200_o or_o if_o 16_o oucne_n be_v allow_v to_o the_o pound_n as_o 1_o to_o 153600._o but_o it_o be_v no_o wonder_n if_o a_o grain_n shall_v affect_v the_o membrane_n at_o stomach_n since_o the_o 1000_o part_n of_o a_o grain_n of_o the_o vomitory_n particle_n of_o crocus_n metallorum_fw-la or_o regulus_n of_o antimony_n do_v affect_v it_o so_o eminent_o as_o many_o other_o thing_n will_v in_o a_o very_a small_a quantity_n whereas_o the_o alter_n of_o the_o blood_n to_o any_o observable_a degree_n require_v the_o use_n of_o alterative_n in_o great_a quantity_n for_o several_a week_n which_o confirm_v the_o former_a conclusion_n that_o opium_n do_v not_o operate_v as_o a_o alterative_a as_o to_o its_o common_a and_o usual_a effect_n ii_o opium_n do_v not_o operate_v by_o grievous_a sensation_n or_o irritation_n as_o vomit_n purger_n errhine_n salivator_n or_o apophlegmatizer_n etc._n etc._n do_v first_o because_o it_o manifest_o cause_v a_o very_a agreeable_a pleasant_a and_o even_o charm_a sensation_n second_o because_o it_o take_v away_o grievous_a sensation_n or_o pain_n thereby_o stop_v vomit_v purge_v and_o all_o other-effect_n of_o grievous_a sensation_n by_o acrimony_n etc._n etc._n as_o for_o the_o vomit_v that_o opium_n sometime_o cause_n it_o be_v only_o as_o shall_v be_v show_v by_o its_o resinous_n part_n stick_v to_o the_o coat_n of_o the_o stomach_n which_o be_v separate_v from_o it_o opium_n have_v no_o such_o effect_n though_o all_o its_o good_a effect_n remain_v so_o its_o purge_v which_o happen_v most_o rare_o and_o only_o when_o a_o great_a quantity_n be_v give_v to_o man_n of_o strong_a digestion_n it_o be_v only_o from_o its_o rosin_n digest_v and_o resolve_v in_o strong_a stomach_n hence_o it_o be_v that_o dog_n and_o such_o as_o have_v canine_a appetite_n do_v general_o purge_v after_o a_o great_a quantity_n of_o crude_a or_o rosinous_n opium_n whereas_o such_o as_o be_v not_o rosinous_n cause_v no_o such_o effect_n but_o of_o these_o matter_n more_o to_o your_o satisfaction_n hereafter_o three_o because_o it_o cause_v all_o effect_n that_o be_v quite_o contrary_a to_o those_o of_o grievous_a sensation_n it_o cause_v a_o ovation_n of_o the_o sensitive_a soul_n and_o spirit_n pain_n or_o grievous_a sensation_n a_o depression_n of_o spirit_n it_o cause_v euphory_n and_o pain_n weariness_n for_o what_o tire_v more_o than_o pain_n or_o labour_v in_o pain_n it_o cause_v good_a humour_n pain_n peevishness_n fretfulness_n and_o ill_a humour_n opium_n cause_v relaxation_n of_o all_o part_n pain_n contraction_n that_o cause_v free_a perspiration_n this_o check_v it_o that_o cause_v sleep_n this_o hinder_v it_o that_o cause_v contentation_n acquiescence_n this_o discontent_n and_o uneasiness_n that_o compose_v this_o discompose_v the_o spirit_n blood_n etc._n etc._n that_o cause_v flux_n by_o irritation_n etc._n etc._n this_o moderate_n or_o stop_v they_o that_o open_v the_o pore_n pain_n constr_v they_o opium_n prevent_v the_o shake_v fit_n in_o ague_n pain_n bring_v they_o on_o that_o cause_v a_o large_a and_o slow_a pulse_n this_o a_o quick_a hard_a and_o narrow_a pulse_n that_o cause_v a_o efflorescence_n of_o the_o skin_n this_o paleness_n that_o pleasant_a this_o unpleasant_a dream_n that_o still_v hiccough_n this_o cause_n they_o that_o take_v off_o contraction_n convulsion_n etc._n etc._n this_o cause_v they_o to_o be_v short_a opium_n cause_v all_o the_o effect_n of_o pleasant_a sensation_n and_o take_v off_o all_o the_o effect_n of_o grievous_a sensation_n what_o can_v be_v a_o more_o evident_a proof_n of_o its_o act_n by_o cause_v a_o pleasant_a sensation_n it_o be_v endless_a to_o mention_v all_o the_o proof_n that_o may_v be_v make_v to_o the_o same_o purpose_n from_o pleaser_n and_o displeaser_n of_o sensation_n therefore_o we_o fair_o conclude_v that_o opium_n do_v not_o operate_v by_o cause_v a_o grievovi_fw-la sensation_n and_o there_o be_v no_o other_o way_n leave_v by_o which_o it_o may_v operate_v it_o must_v operate_v by_o cause_v a_o pleasant_a sensation_n which_o be_v the_o true_a and_o plain_a reason_n why_o as_o have_v be_v show_v it_o take_v off_o pain_n and_o cause_v all_o effect_n quite_o contrary_a to_o that_o of_o grievous_a sensation_n irritation_n by_o acrimony_n etc._n etc._n which_o be_v most_o eminent_a upon_o the_o most_o sensible_a part_n as_o the_o stomach_n intestine_n venereal_a membrane_n skin_n etc._n etc._n as_o you_o may_v observe_v where_o the_o effect_n of_o opium_n be_v enumerate_v now_o gentle_a reader_n consider_v that_o contrary_n be_v the_o true_a cure_n of_o contrary_n what_o can_v then_o cure_v pain_n and_o all_o its_o effect_n better_a than_o pleasure_n it_o be_v very_o strange_a then_o that_o million_o for_o many_o age_n find_v opium_n cure_v or_o take_v off_o pain_n and_o all_o its_o effect_n above_o all_o thing_n shall_v not_o attribute_v its_o so_o do_v to_o its_o cause_v a_o pleasant_a sensation_n which_o be_v the_o direct_a contrary_n to_o pain_n especial_o since_o every_o man_n that_o take_v opium_n feel_v a_o actual_a pleasure_n upon_o take_v thereof_o pleasant_a dream_n a_o pleasant_a humour_n etc._n etc._n it_o may_v be_v say_v what_o if_o it_o be_v grant_v that_o opium_n operate_v by_o a_o please_a sensation_n which_o i_o will_v thank_v none_o for_o that_o have_v feel_v at_o stomach_n or_o reason_n at_o brain_n how_o be_v it_o possible_a that_o such_o pleasant_a sensation_n shall_v cause_v and_o explicate_v all_o the_o various_a strange_a wonderful_a mysterious_a and_o very_o often_o seem_o contradictory_n phenomena_n and_o effect_n of_o opium_n answer_n as_o easy_o as_o ever_o i_o explain_v any_o thing_n in_o nature_n especial_o if_o my_o tract_n of_o animal_n mechanism_n be_v publish_v but_o it_o be_v my_o misfortune_n that_o it_o be_v not_o however_o it_o shall_v not_o be_v the_o reader_n though_o it_o will_v put_v i_o to_o a_o great_a trouble_n to_o evade_v which_o be_v none_o of_o my_o intention_n by_o those_o word_n but_o rather_o to_o bespeak_v the_o reader_n be_v patience_n while_n i_o be_o premise_v some_o necessary_a praecognita_fw-la requisite_a to_o be_v know_v before_o i_o enter_v upon_o the_o explication_n of_o the_o wonderful_a and_o seem_o inexplicable_a effect_n of_o opium_n i_o therefore_o desire_v the_o reader_n be_v leave_v to_o premise_v some_o thing_n of_o the_o nature_n of_o sensation_n and_o sensitive_a pleasure_n in_o order_n to_o his_o more_o clear_a and_o ready_a understanding_n my_o explication_n of_o this_o mysterious_a and_o momentous_a matter_n look_v upon_o as_o so_o dark_a and_o abstruse_a a_o business_n to_o this_o day_n that_o some_o have_v not_o only_o yield_v it_o up_o as_o a_o thing_n hide_v from_o mankind_n but_o have_v earnest_o and_o serious_o argue_v that_o it_o act_v absolute_o by_o a_o occult_a quality_n reserve_v in_o a_o special_a manner_n as_o be_v the_o nature_n of_o spirit_n from_o our_o knowledge_n that_o it_o have_v be_v so_o hitherto_o i_o think_v none_o can_v deny_v as_o the_o circulation_n of_o the_o blood_n be_v for_o thousand_o of_o year_n though_o the_o very_a motion_n be_v see_v by_o million_o so_o as_o the_o cause_n of_o the_o operation_n of_o opium_n have_v be_v feel_v by_o a_o far_o great_a number_n it_o therefore_o will_v if_o i_o fail_v not_o in_o explain_v it_o appear_v so_o clear_a that_o it_o will_v be_v much_o wonder_v at_o like_o that_o of_o the_o circulation_n of_o the_o blood_n why_o so_o obvious_a a_o thing_n be_v not_o find_v by_o every_o one_o that_o use_v opium_n but_o whatever_o opium_n be_v god_n method_n be_v unsearchable_a and_o often_o his_o wise_a providence_n bestow_v good_a gift_n upon_o the_o unworthy_a that_o his_o free_a goodness_n may_v appear_v to_o who_o be_v all_o glory_n praise_n and_o thanksgiving_n for_o ever_o and_o ever_o amen_n note_v that_o while_o i_o be_o upon_o the_o
as_o appear_v by_o several_a place_n or_o passage_n of_o the_o premise_n and_o in_o the_o wake_a more_o than_o in_o such_o as_o be_v asleep_a 6._o it_o be_v manifest_a that_o they_o be_v elastic_a by_o their_o spring_v into_o a_o limb_n hold_v up_o or_o down_o and_o that_o with_o such_o force_n as_o to_o cause_v a_o great_a pain_n after_o they_o have_v be_v exclude_v from_o it_o by_o some_o accident_n as_o lean_v or_o press_v too_o hard_o upon_o a_o nerve_n etc._n etc._n for_o neither_o levity_n nor_o gravity_n can_v do_v so_o especial_o both_o up_o and_o down_o as_o be_v say_v nor_o be_v there_o any_o propulsory_a engine_n for_o they_o as_o be_v for_o the_o blond_n therefore_o it_o must_v be_v from_o their_o springiness_n 7._o they_o can_v not_o cause_v brisk_a and_o smart_a tremulous_a motion_n in_o the_o body_n if_o they_o be_v not_o elastic_a for_o such_o can_v be_v conceive_v by_o any_o mean_n without_o it_o but_o there_o be_v several_a brisk_a and_o smart_a tremulous_a motion_n cause_v by_o the_o animal_n spirit_n as_o in_o the_o shivering_n of_o ague_n fit_n fright_v cold_a surprise_v sudden_a or_o exquisite_a pain_n tremor_n of_o the_o hand_n head_z etc._n etc._n in_o old_a age_n in_o some_o conuâ—_n etc._n etc._n therefore_o the_o animal_n spirit_n that_o cause_v they_o be_v elastic_a 8._o muscle_n have_v no_o springiness_n of_o themselves_o when_o the_o animal_n spirit_n be_v exclude_v from_o they_o as_o in_o palsy_n etc._n etc._n but_o all_o muscle_n in_o their_o exertion_n be_v very_o springy_a insomuch_o that_o if_o you_o hold_v any_o of_o they_o back_o or_o restrain_v they_o from_o their_o motion_n and_o again_o sudden_o leave_v they_o at_o liberty_n during_o the_o exertion_n they_o or_o any_o part_n move_v by_o they_o will_v spring_v out_o very_o violent_o as_o in_o flip_v a_o arm_n hold_v back_o etc._n etc._n but_o nothing_o prove_v this_o matter_n better_o than_o the_o tongue_n in_o form_v the_o sound_n of_o the_o letter_n r_n for_o in_o that_o case_n the_o tongue_n after_o it_o be_v put_v in_o tension_n and_o exertion_n be_v sudden_o hit_v against_o the_o inside_n or_o gum_n of_o the_o upper_a tooth_n do_v thereupon_o as_o springy_a body_n use_v to_o do_v fall_v into_o a_o tremulous_a motion_n or_o jar_a that_o cause_v the_o snarl_a sound_n of_o r_n which_o nothing_o but_o springy_a matter_n can_v do_v 9_o be_v they_o not_o springy_a they_o can_v never_o convey_v the_o tremulous_a motion_n of_o sound_n to_o the_o sensitive_a soul_n and_o indeed_o over_o all_o the_o systeme_n of_o the_o nerve_n by_o which_o be_v cause_v as_o may_v be_v prove_v that_o motion_n of_o consent_n call_v dance_v and_o the_o finger_n etc._n etc._n to_o move_v and_o keep_v time_n with_o the_o music_n even_o when_o it_o or_o the_o finger_n be_v not_o as_o much_o as_o think_v of_o because_o the_o animal_n spirit_n have_v the_o same_o capacity_n with_o the_o air_n to_o receive_v and_o convey_v it_o by_o reason_n of_o their_o springiness_n and_o great_a by_o reason_n of_o their_o more_o forcible_a compression_n by_o the_o vigilative_a contraction_n supper_n add_v to_o the_o compression_n of_o the_o air_n under_o which_o they_o be_v as_o well_o as_o the_o air_n itself_o as_o plain_a reason_n tell_v we_o for_o that_o which_o compress_n the_o whole_a body_n must_v needs_o compress_v the_o animal_n spirit_n the_o experiment_n of_o the_o air-pump_n do_v confirm_v the_o same_o 10._o there_o can_v be_v no_o doubt_n but_o the_o animal_n spirit_n be_v nourish_v or_o sustain_v by_o the_o air_n if_o they_o be_v not_o air_n therefore_o they_o be_v elastic_a what_o need_v any_o more_o argument_n when_o several_a of_o the_o former_a be_v demonstrative_a and_o that_o 11._o all_o physician_n and_o philosopher_n that_o i_o know_v of_o do_v allow_v that_o the_o animal_n spirit_n be_v elastic_a second_o it_o be_v requisite_a as_o be_v say_v of_o the_o external_n medium_fw-la that_o they_o shall_v be_v compress_v to_o render_v they_o fit_a to_o convey_v impression_n and_o that_o they_o be_v compress_v be_v evident_a as_o be_v before_o intimate_v 1._o by_o the_o atmosphere_n 2._o by_o the_o vigilative_a contraction_n which_o make_v they_o much_o more_o dispose_v to_o convey_v impression_n than_o the_o external_n medium_fw-la beside_o that_o very_o often_o two_o other_o contradiction_n that_o be_v show_v in_o the_o remain_a part_n of_o this_o chapter_n be_v add_v thereto_o and_o that_o the_o animal_n spirit_n be_v whole_o contain_v in_o pipe_n to_o prevent_v their_o expansion_n and_o that_o of_o the_o narrow_a size_n that_o can_v well_o be_v imagine_v but_o the_o air_n or_o external_n medium_fw-la be_v at_o large_a in_o the_o atmosphere_n so_o that_o all_o the_o impression_n make_v upon_o the_o animal_n spirit_n be_v very_o tight_o close_o and_o smart_o convey_v nor_o have_v they_o but_o a_o little_a way_n to_o pass_v that_o be_v the_o length_n of_o the_o animal_n at_o most_o which_o also_o may_v be_v some_o advantage_n to_o small_a creature_n but_o in_o sleep_n the_o vigilative_a contraction_n be_v lose_v and_o the_o animal_n spirit_n thereupon_o expanded_a all_o impulse_n must_v needs_o be_v carry_v very_o faint_o both_o because_o the_o organ_n or_o membrane_n be_v indispose_v by_o relaxation_n and_o the_o animal_n spirit_n by_o expansion_n upon_o that_o relaxation_n for_o want_v of_o due_a compression_n to_o fit_v they_o thus_o have_v you_o after_o many_o vain_a inquiry_n the_o true_a mechanical_a cause_n of_o the_o difference_n of_o sensation_n sleep_v and_o wake_v and_o the_o plain_a reason_n why_o our_o motion_n be_v so_o feeble_a in_o sleep_n viz._n because_o the_o animal_n spirit_n have_v lose_v much_o of_o their_o force_n springiness_n etc._n etc._n for_o want_n of_o due_a compression_n by_o reason_n of_o the_o relaxation_n of_o all_o the_o vessel_n that_o include_v the_o spirit_n three_o it_o be_v in_o some_o measure_n requisite_a that_o the_o animal_n spirit_n shall_v have_v a_o homogeneous_a continuity_n as_o be_v show_v by_o the_o analogy_n of_o the_o external_n medium_fw-la which_o do_v not_o convey_v impression_n as_o well_o in_o the_o heat_n of_o the_o day_n as_o in_o the_o night_n or_o after_o sunset_n because_o its_o part_n be_v more_o discontinue_v and_o disgregated_a by_o the_o particle_n of_o heat_n fume_n etc._n etc._n in_o the_o day_n time_n nay_o if_o thing_n be_v discontinue_v they_o never_o carry_v impression_n so_o well_o though_o place_v contiguous_o afterward_o thus_o a_o long_a tree_n that_o convey_v sound_n so_o exact_o from_o one_o end_n to_o the_o other_o while_o all_o be_v continue_v and_o in_o one_o piece_n will_v not_o convey_v the_o sound_n so_o well_o if_o it_o be_v cut_v into_o many_o piece_n though_o they_o be_v afterward_o put_v close_o one_o to_o the_o other_o as_o to_o this_o matter_n of_o continuity_n in_o the_o animal_n spirit_n see_v it_o do_v not_o much_o concern_v we_o and_o that_o people_n in_o a_o state_n of_o health_n be_v suppose_v to_o have_v it_o and_o that_o it_o be_v not_o our_o business_n here_o to_o enter_v upon_o the_o consideration_n of_o nervous_a distemper_n i_o need_v not_o use_v any_o more_o word_n about_o it_o but_o that_o if_o it_o any_o way_n happen_v to_o be_v discontinue_v as_o either_o by_o the_o penury_n thereof_o that_o they_o do_v not_o quite_o fill_v all_o part_n of_o their_o vessel_n or_o any_o matter_n intercept_n their_o part_n or_o that_o the_o vessel_n shall_v be_v so_o relax_v or_o widen_v that_o the_o animal_n spirit_n can_v so_o well_o fill_v they_o up_o etc._n etc._n such_o cause_n must_v destroy_v or_o lessen_v sensation_n though_o the_o bare_a mix_n of_o fume_n with_o they_o will_v not_o consider_v the_o shortness_n of_o the_o way_n that_o impression_n be_v carry_v in_o animal_n much_o alter_v the_o case_n as_o you_o find_v fume_n in_o the_o air_n do_v not_o much_o hinder_a sound_n at_o the_o distance_n of_o a_o yard_n or_o two_o wherein_o it_o be_v insensible_a to_o common_a observer_n at_o least_o so_o that_o if_o some_o fume_n from_o a_o grain_n or_o two_o of_o opium_n do_v mingle_v with_o the_o animal_n spirit_n it_o will_v not_o cause_v a_o sensible_a difference_n of_o feel_v in_o the_o short_a space_n of_o the_o length_n of_o a_o animal_n but_o i_o have_v prove_v that_o no_o such_o fume_v from_o the_o opium_n mix_v with_o they_o therefore_o need_v say_v no_o more_o of_o this_o matter_n v._o the_o office_n or_o business_n of_o the_o sensitive_a soul_n in_o the_o oeconomy_n of_o sensation_n be_v to_o perceive_v the_o impression_n convey_v to_o he_o by_o the_o animal_n spirit_n that_o he_o may_v if_o he_o find_v they_o disagreeable_a bestir_v himself_o in_o defence_n of_o the_o animal_n first_o it_o be_v requisite_a he_o shall_v attend_v to_o all_o impression_n offer_v he_o by_o the_o animal_n spirit_n otherwise_o
impression_n of_o great_a concernment_n may_v escape_v his_o notice_n and_o consequent_o want_v his_o assistance_n by_o way_n of_o defence_n for_o it_o be_v manifest_a that_o when_o his_o attention_n be_v divert_v by_o any_o object_n more_o especial_o by_o such_o as_o mighty_o please_v he_o as_o in_o the_o act_n of_o venery_n and_o other_o pleasure_n especial_o if_o intense_a that_o he_o do_v not_o perceive_v other_o object_n at_o the_o time_n that_o he_o be_v so_o divert_v and_o if_o the_o pleasant_a diversion_n be_v intense_a and_o permanent_a as_o in_o the_o case_n of_o opium_n and_o wine_n drink_v in_o a_o considerable_a quantity_n he_o be_v so_o take_v up_o divert_v or_o charm_v therewith_o that_o he_o do_v not_o attend_v to_o the_o business_n of_o sensation_n this_o be_v one_o reason_n why_o such_o as_o be_v far_o go_v in_o drink_n have_v none_o of_o their_o sense_n aright_o but_o as_o to_o the_o illustration_n of_o this_o matter_n you_o may_v expect_v more_o hereafter_o note_v that_o the_o sensitive_a soul_n be_v the_o only_a thing_n iâ—_n a_o animal_n that_o have_v perception_n and_o therefore_o the_o only_a thing_n that_o be_v sensible_a of_o any_o grievance_n weariness_n hunger_n pleasure_n comfort_n etc._n etc._n second_o it_o be_v requisite_a that_o it_o shall_v use_v all_o mean_n that_o be_v in_o its_o power_n that_o the_o impression_n shall_v be_v bring_v to_o it_o very_o entire_o exact_o smart_o etc._n etc._n so_o as_o to_o have_v due_a notice_n of_o all_o object_n and_o the_o small_a impression_n that_o may_v be_v for_o which_o good_a end_n and_o purpose_v god_n have_v endue_v the_o sensitive_a soul_n as_o will_v be_v full_o prove_v with_o a_o power_n of_o contract_v all_o the_o sensile_n small_a and_o slender_a pipe_n vessel_n or_o passage_n of_o the_o animal_n spirit_n for_o the_o more_o express_a distinct_a and_o accurate_a conveyance_n of_o all_o impression_n by_o the_o help_n of_o compression_n therefore_o the_o sensitive_a soul_n take_v the_o advantage_n thereof_o for_o better_a information_n in_o order_n to_o self-preservation_n do_v by_o the_o appointment_n of_o the_o preserver_n of_o all_o thing_n execute_v his_o power_n by_o the_o aforementioned_a vigilative_a contraction_n of_o those_o part_n to_o cause_v their_o tension_n and_o great_a compression_n of_o the_o animal_n spirit_n to_o improve_v the_o impression_n that_o be_v to_o be_v convey_v to_o he_o and_o render_v they_o more_o observable_a this_o god_n who_o have_v make_v nothing_o to_o be_v idle_a and_o particular_o order_v the_o sensitive_a soul_n in_o adam_n for_o labour_n especeal_o in_o reference_n to_o their_o own_o safety_n and_o preservation_n have_v make_v to_o be_v the_o ordinary_a employ_v or_o day-work_a of_o the_o sensitive_a soul_n that_o by_o the_o say_v vigilative_a contraction_n the_o organ_n membrane_n vessel_n etc._n etc._n may_v be_v render_v more_o tense_n and_o firm_a and_o the_o animal_n spirit_n more_o compress_v springy_a prompt_a flippant_a and_o forcible_a for_o the_o benefit_n of_o sense_n and_o motion_n upon_o all_o occasion_n of_o defence_n flight_n struggle_v etc._n etc._n which_o be_v our_o state_n of_o vigilancy_n as_o have_v be_v intimate_v but_o the_o keep_n of_o the_o say_a part_n membrane_n etc._n etc._n in_o continual_a contraction_n even_o against_o the_o renitency_n of_o the_o elastic_a spirit_n which_o resist_v and_o thrust_v the_o hard_a against_o their_o vessel_n by_o how_o much_o the_o more_o they_o compress_v they_o by_o the_o vigilative_a contraction_n be_v a_o continual_a tedious_a labour_n and_o fatigue_n of_o which_o the_o sensitive_a soul_n be_v sensible_a as_o the_o only_a perceiver_n of_o lassitude_n or_o indeed_o of_o any_o thing_n beside_o in_o a_o animal_n and_o in_o his_o nature_n but_o material_a changeable_a fatigable_a frail_a subject_a to_o be_v wear_v out_o and_o capable_a of_o decay_n which_o make_v the_o certainty_n of_o death_n in_o all_o animal_n and_o in_o we_o since_o the_o fall_n into_o a_o animal_n nature_n do_v upon_o that_o account_n and_o lest_o the_o continual_a contraction_n and_o tensive_a stress_n of_o part_n by_o that_o mean_n shall_v spoil_v their_o tone_n and_o to_o recruit_v the_o waste_a spirit_n by_o rest_n after_o tuggingall_a day_n at_o the_o vigilative_a contraction_n grow_v willing_a to_o give_v over_o the_o drudgery_n however_o convenient_a for_o the_o use_v aforesaid_a therefore_o be_v allow_v convenient_a rest_n by_o his_o maker_n he_o for_o the_o great_a benefit_n of_o refection_n without_o which_o he_o can_v continue_v his_o be_v and_o for_o the_o sweetness_n of_o ease_n loosen_v the_o reins_o of_o vigilative_a contraction_n whereupon_o sensation_n and_o promptitude_n to_o motion_n which_o be_v maintain_v by_o that_o contraction_n cause_v the_o tension_n of_o organ_n and_o compression_n of_o the_o animal_n spirit_n as_o have_v be_v mechanical_o demonstrate_v fail_v by_o the_o relaxation_n of_o those_o organ_n membrane_n and_o vessel_n of_o the_o spirit_n and_o the_o consequent_a expansion_n of_o the_o animal_n spirit_n so_o that_o now_o only_a the_o compression_n of_o the_o atmosphere_n remain_v which_o as_o you_o see_v in_o a_o gut_n half_n full_a of_o air_n under_o that_o pressure_n be_v not_o sufficient_a to_o convey_v the_o impression_n with_o any_o smartness_n or_o cause_v the_o animal_n spirit_n to_o spring_v vigorous_o into_o motion_n which_o decay_n or_o failure_n of_o sense_n and_o motion_n by_o relaxation_n and_o the_o consequent_a expansion_n of_o the_o animal_n spirit_n be_v the_o state_n of_o natural_a sleep_n note_v that_o relaxation_n be_v a_o necessary_a consequence_n of_o the_o privation_n of_o contraction_n and_o require_v no_o labour_n but_o a_o bare_a remission_n of_o that_o contraction_n note_v that_o the_o watch_a part_n of_o our_o life_n be_v uphold_v by_o force_n and_o that_o nullum_fw-la violentum_fw-la est_fw-la diuturnum_fw-la and_o consequent_o a_o necessity_n of_o sleep_n and_o at_o last_o of_o death_n itself_o thus_o have_v you_o the_o true_a reason_n of_o sleep_v and_o watch_v which_o will_v natural_o plain_o and_o easy_o solve_v all_o the_o phenomena_n thereof_o for_o it_o be_v most_o evident_a from_o the_o premise_n 1._o why_o watch_v and_o sleep_v observe_v a_o proportion_n between_o they_o the_o be_v tire_v with_o one_o be_v the_o cause_n of_o the_o other_o 2._o why_o sense_n and_o motion_n do_v fail_v so_o much_o in_o sleep_n viz._n by_o the_o relaxation_n of_o all_o part_n and_o expansion_n of_o the_o animal_n spirit_n 3._o why_o they_o always_o fail_v together_o and_o in_o like_a proportion_n 4._o why_o they_o do_v not_o whole_o fail_v in_o sleep_n because_o the_o compressure_n of_o the_o atmosphere_n etc._n etc._n remain_v 5._o why_o in_o sleep_v the_o limb_n be_v like_o a_o gut_n half_n full_a of_o air_n lax_n limber_a flaccid_a and_o yield_v all_o manner_n of_o way_n because_o all_o the_o innumerable_a small_a vessel_n that_o contain_v the_o elastic_a animal_n spirit_n be_v as_o that_o half_a fill_v gut_n i_o mention_v not_o tight_o fill_v which_o if_o they_o be_v will_v be_v firm_a and_o tense_n as_o such_o a_o gut_n blow_v up_o very_o full_a and_o forcible_o be_v which_o vessel_n be_v all_o over_o the_o body_n confirm_v the_o whole_a tone_n when_o we_o be_v awake_a and_o the_o vigilative_a contraction_n compress_n the_o animal_n spirit_n into_o a_o steadiness_n and_o as_o it_o be_v a_o kind_a of_o solidity_n 6._o why_o as_o appear_v by_o statick_a demonstration_n and_o experiment_n we_o perspire_v more_o when_o asleep_a than_o awake_a because_o the_o pore_n be_v close_v by_o the_o vigilative_a contraction_n and_o open_v in_o sleep_n by_o the_o contrary_a relaxation_n which_o therefore_o always_o cause_v free_a perspiration_n where_o ever_o it_o happen_v as_o in_o faint_a fit_n syncopes_fw-la leipothymy_n and_o by_o warmth_n especial_o if_o moist_a and_o emollient_a as_o in_o bath_n fomentation_n foot_n wash_v head_n wash_v etc._n etc._n as_o also_o when_o pleasure_n relax_n as_o in_o the_o act_n of_o venery_n great_a joy_n after_o good_a meal_n or_o some_o glass_n of_o wine_n etc._n etc._n all_o which_o cause_n plentiful_a perspiration_n because_o they_o relax_v and_o thereby_o open_a the_o pore_n as_o more_o full_o appear_v in_o the_o follow_a discourse_n by_o reason_n of_o the_o pleasure_n that_o they_o cause_n which_o divert_v the_o sensitive_a soul_n from_o his_o employ_v of_o contraction_n 7._o why_o the_o pore_n be_v open_a by_o the_o relaxation_n we_o sweat_v in_o our_o sleep_n if_o we_o be_v fill_v with_o matter_n for_o it_o viz._n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o be_v much_o sweat_v in_o sleep_n argue_v that_o much_o food_n or_o nutriment_n be_v take_v of_o which_o drink_n be_v the_o great_a part_n in_o bulk_n even_o in_o sober_a person_n i_o mention_v this_o to_o show_v the_o difference_n in_o the_o case_n of_o perspiration_n and_o sweat_v for_o that_o always_o happen_v in_o sleep_n but_o not_o sweat_v unless_o
the_o body_n be_v well_o fill_v with_o moisture_n to_o show_v the_o cause_n of_o which_o difference_n will_v be_v the_o business_n of_o my_o tract_n of_o animal_n mechanism_n if_o i_o have_v not_o hereafter_o a_o occasion_n to_o do_v it_o in_o this_o tract_n as_o i_o suppose_v i_o may_v 8._o why_o sleep_n cure_v cold_n by_o open_v the_o pore_n 9_o why_o the_o skin_n be_v more_o florid_n in_o sleep_n because_o as_o have_v be_v say_v it_o be_v relax_v admit_v the_o blood_n into_o it_o which_o vigilative_a contraction_n do_v in_o good_a measure_n repel_v and_o thereby_o cause_v the_o skin_n to_o appear_v more_o white_a and_o pale_a as_o it_o be_v and_o any_o one_o may_v observe_v upon_o awake_v 10._o why_o the_o eye_n look_v deadish_a in_o sleep_n viz._n because_o as_o have_v be_v show_v the_o humour_n do_v not_o fill_v up_o the_o relax_v cornea_n to_o a_o due_a tension_n and_o rotundity_n which_o as_o be_v say_v make_v the_o cornea_n shine_v sparkle_v and_o particular_o to_o reflect_v a_o brisk_a speck_n of_o light_n as_o shine_v round_a thing_n must_v do_v which_o speck_n if_o painter_n omit_v the_o eye_n look_v deadish_a therefore_o they_o shall_v when_o they_o have_v a_o mind_n to_o express_v the_o deadness_n of_o the_o eye_n as_o in_o faint_v fit_n syncopes_fw-la sleep_n death_n wanton_a loose_a ogling_n of_o lover_n drunkenness_n etc._n etc._n omit_v that_o speck_n or_o rather_o draw_v it_o dull_a wide_a and_o discompose_v in_o figure_n with_o the_o pupil_n very_o large_a and_o the_o upper_a eyelid_n fall_v down_o loose_o which_o will_v exact_o express_v the_o deadness_n of_o the_o eye_n in_o all_o those_o case_n of_o relaxation_n in_o which_o alone_o it_o so_o appear_v note_v that_o the_o reason_n why_o some_o in_o such_o case_n see_v divers_a colour_n before_o their_o eye_n be_v because_o the_o uneven_a cornea_n various_o retract_v and_o reflect_v the_o light_n which_o i_o mention_v because_o none_o that_o i_o know_v of_o have_v observe_v the_o cause_n 11._o why_o people_n be_v more_o sleepy_a in_o warm_a moist_a wether_n viz._n because_o the_o part_n be_v more_o relax_v and_o the_o pressure_n of_o the_o atmosphere_n less_o to_o assist_v the_o vigilative_a contraction_n to_o keep_v we_o in_o a_o wake_a state_n by_o the_o compressure_n of_o the_o animal_n spirit_n how_o much_o better_a therefore_o be_v a_o cool_a and_o dry_a air_n that_o raise_v the_o mercury_n high_a in_o the_o barometer_n or_o wether_n glass_n both_o for_o heath_n and_o action_n because_o it_o render_v the_o animal_n spirit_n more_o powerful_a prompt_a and_o flippant_a by_o the_o compression_n this_o shall_v be_v observe_v by_o such_o as_o be_v to_o run_v race_n alone_o lift_v weight_n or_o perform_v any_o thing_n that_o require_v strength_n vigour_n or_o speed_v nor_o can_v i_o doubt_v but_o if_o we_o have_v a_o artificial_a mean_n to_o compress_v man_n body_n in_o a_o high_a manner_n as_o by_o put_v they_o into_o convenient_a cavity_n and_o force_v air_n upon_o they_o but_o they_o will_v be_v much_o strong_a for_o the_o time_n and_o thereby_o enable_v to_o do_v exploit_n beyond_o their_o ordinary_a strength_n which_o put_v i_o in_o mind_n of_o several_a thing_n that_o confirm_v it_o very_o much_o as_o man_n lift_v of_o great_a weight_n in_o low_a place_n than_o on_o the_o top_n of_o very_o high_a hill_n where_o the_o pressure_n of_o the_o air_n be_v less_o to_o compress_v the_o animal_n spirit_n the_o contraction_n of_o all_o part_n in_o lift_v of_o great_a weight_n the_o prodigious_a leap_v and_o swiftness_n of_o some_o person_n in_o great_a fright_v terror_n etc._n etc._n which_o mighty_o contract_v the_o sensile_a part_n and_o vessel_n of_o the_o animal_n spirit_n by_o which_o mean_v they_o be_v render_v more_o springy_a and_o powerful_a note_v that_o the_o true_a cause_n of_o strength_n be_v the_o compression_n of_o the_o animal_n spirit_n and_o that_o probable_o the_o force_n of_o muscle_n may_v some_o way_n or_o other_o depend_v upon_o it_o which_o be_v not_o my_o business_n to_o explain_v at_o present_a note_v that_o it_o be_v the_o membrane_n be_v primary_o contract_v and_o the_o medullary_a part_n of_o the_o nerve_n spirit_n etc._n etc._n compress_a thereby_o by_o consequence_n 12._o why_o the_o soft_a flesh_v and_o moist_a be_v more_o sleepy_a as_o child_n etc._n etc._n viz._n because_o the_o compression_n of_o their_o animal_n spirit_n be_v not_o so_o great_a by_o reason_n of_o the_o laxity_n of_o their_o part_n so_o be_v they_o weak_a for_o the_o same_o reason_n which_o tell_v you_o why_o little_a man_n who_o flesh_n be_v firm_a that_o be_v no_o big_a than_o boy_n be_v much_o strong_a than_o boy_n or_o woman_n of_o the_o same_o bigness_n 13._o why_o warm_a and_o emollient_a bath_n fomentation_n foot_n or_o head_n wash_v etc._n etc._n do_v as_o moist_a and_o warm_a wether_n cause_n sleepiness_n and_o indeed_o all_o thing_n that_o cause_n relaxation_n or_o incline_v the_o sensitive_a soul_n to_o leave_v off_o contract_n as_o weariness_n etc._n etc._n do_v cause_n sleep_v note_v that_o in_o dry_a body_n as_o old_a people_n etc._n etc._n such_o emollient_a bath_n fomentation_n etc._n etc._n with_o the_o use_n of_o emollient_a moistner_n inward_o will_v cause_v sleep_n very_o fine_o when_o opium_n itself_o will_v not_o and_o that_o opium_n in_o such_o case_n shall_v be_v use_v with_o such_o thing_n both_o internal_o and_o external_o but_o which_o be_v not_o observe_v the_o bath_n fomentation_n etc._n etc._n shall_v not_o be_v above_o the_o warmth_n of_o blood_n because_o the_o heat_n may_v otherwise_o cause_v too_o much_o motion_n of_o the_o blood_n and_o spirit_n which_o be_v a_o great_a enemy_n to_o sleep_n that_o consist_v in_o their_o rest_n and_o the_o aforesaid_a relaxation_n of_o part_n by_o both_o which_o cooperate_a you_o may_v and_o can_v fail_v to_o cause_v any_o man_n to_o sleep_n if_o you_o can_v make_v they_o concur_v 14._o the_o same_o relaxation_n cause_v the_o pulse_n to_o be_v large_a and_o slow_a in_o sleep_n nocturnal_a pollution_n want_v of_o due_a contraction_n and_o sensation_n at_o stomach_n by_o which_o mean_v the_o meat_n stay_v long_a there_o in_o our_o sleep_n than_o when_o we_o be_v awake_a so_o 15._o fret_n commotion_n and_o perturbation_n of_o the_o spirit_n etc._n etc._n be_v compose_v by_o sleep_n because_o the_o sensitive_a soul_n who_o be_v the_o original_a of_o all_o motion_n be_v at_o rest_n and_o that_o the_o animal_n spirit_n be_v expanded_a be_v near_o their_o absolute_a rest_n which_o consist_v in_o a_o full_a and_o perfect_a expansion_n so_o that_o there_o be_v no_o far_a endeavour_n towards_o motion_n 16._o sensation_n be_v much_o lessen_v by_o the_o expansion_n of_o the_o animal_n spirit_n upon_o the_o say_a relaxation_n the_o sense_n of_o the_o irritation_n of_o humour_n be_v thereby_o lessen_v or_o quite_o take_v away_o whereupon_o all_o flux_n occasion_v by_o the_o irritation_n of_o humour_n as_o diarrhea_n disentery_n catarrh_n etc._n etc._n be_v stop_v or_o moderate_v at_o least_o by_o sleep_n beside_o that_o relaxation_n be_v quite_o contrary_a to_o contraction_n by_o which_o those_o humour_n be_v squeeze_a out_o let_v we_o the_o humour_n stay_v quiet_o where_o they_o be_v relaxation_n be_v more_o for_o receive_v contain_v detain_v and_o suspending_a humour_n in_o the_o part_n than_o send_v they_o forward_o as_o you_o see_v in_o a_o sponge_n first_o contract_v and_o afterward_o suffer_v to_o dilate_v or_o expand_v itself_o in_o a_o dish_n that_o have_v some_o water_n in_o it_o which_o it_o take_v into_o itself_o and_o suspend_v till_o something_o squeese_v it_o out_o by_o contract_v it_o 17._o therefore_o it_o be_v that_o the_o spital_n do_v not_o come_v into_o the_o mouth_n in_o sleep_n or_o very_o little_a and_o that_o people_n be_v apt_a to_o awake_v thirsty_a though_o it_o be_v soon_o take_v off_o in_o some_o measure_n by_o the_o vigilative_a contraction_n squeeze_v out_o the_o spital_n into_o the_o mouth_n unless_o there_o be_v some_o special_a cause_n to_o the_o contrary_n 18._o for_o the_o same_o reason_n the_o menstruum_fw-la of_o the_o stomach_n come_v but_o very_o slow_o into_o the_o stomach_n in_o sleep_n which_o be_v one_o cause_v that_o digestion_n go_v on_o but_o slow_o in_o sleep_n note_v that_o digestion_n and_o send_v the_o chyle_n out_o of_o the_o stomach_n depend_v both_o upon_o contraction_n they_o be_v hasten_v and_o retard_v in_o exact_a proportion_n so_o that_o the_o extrusion_n keep_v equal_a pace_n with_o the_o digestion_n how_o equal_a and_o due_o proportion_v be_v the_o work_n of_o nature_n 19_o it_o be_v plain_a also_o from_o what_o have_v be_v state_v concern_v sleep_n why_o ague_n fit_v seldom_o if_o ever_o take_v people_n in_o the_o time_n of_o their_o first_o sound_n sleep_v because_o the_o shiver_a be_v cause_v by_o a_o grievous_a
sensation_n of_o the_o sensile_a part_n which_o can_v well_o happen_v in_o that_o sound_a sleep_n wherein_o there_o be_v so_o little_a feel_v by_o reason_n of_o the_o say_a relaxation_n and_o because_o relaxation_n oppose_v contraction_n by_o which_o that_o shiver_a be_v promote_v such_o a_o relaxation_n and_o failure_n of_o feel_v thereupon_o be_v the_o true_a cause_n why_o opium_n put_v off_o ague_n fit_n etc._n etc._n so_o 20._o the_o relaxation_n in_o sleep_n stop_v vomit_v by_o take_v away_o the_o sense_n of_o the_o irritate_v cause_n and_o quiet_v as_o i_o have_v intimate_v all_o motion_n in_o general_a so_o sleep_v stop_n hiccough_n hemorrhage_n diary_n fever_n etc._n etc._n 21._o why_o watch_v labour_n or_o what_o impair_v the_o spirit_n and_o tire_v the_o sensitive_a soul_n incline_v we_o to_o sleep_v that_o be_v dispose_v the_o sensitive_a soul_n the_o only_a feeler_n of_o lassitude_n to_o give_v over_o contract_n the_o sensile_a part_n which_o as_o will_v plain_o appear_v by_o and_o by_o spend_v the_o spirit_n as_o sleep_v by_o relax_v they_o cause_v a_o recruit_v thereof_o to_o be_v short_a though_o one_o can_v hardly_o be_v too_o long_o in_o solve_v phenomena_n which_o be_v the_o proof_n of_o the_o truth_n of_o a_o man_n assertion_n the_o mechanical_a demonstration_n that_o i_o have_v make_v of_o the_o state_n of_o sleep_v and_o wake_v do_v so_o evident_o explicate_v all_o the_o phenomena_n of_o both_o that_o i_o be_o even_o ashamed_a to_o run_v any_o far_o upon_o such_o plain_a matter_n so_o obvious_a be_v thing_n when_o the_o truth_n be_v know_v and_o therefore_o have_v mention_v those_o circumstance_n and_o effect_n of_o sleep_n that_o main_o concern_v we_o i_o must_v give_v over_o lest_o the_o world_n shall_v think_v that_o i_o take_v all_o my_o reader_n to_o be_v idiot_n by_o use_v too_o many_o word_n in_o so_o obvious_a a_o thing_n or_o that_o i_o be_o no_o better_o for_o use_v they_o without_o cause_n for_o the_o truth_n of_o this_o matter_n seem_v to_o i_o to_o outshine_v all_o the_o argument_n i_o can_v make_v for_o it_o such_o splendour_n do_v truth_n show_v upon_o the_o first_o glimpse_n thereof_o as_o i_o take_v the_o account_n i_o give_v of_o sleep_n and_o watch_v to_o be_v for_o the_o opinion_n i_o have_v meet_v concern_v they_o be_v quite_o contrary_a to_o or_o very_o remote_a from_o what_o i_o have_v state_v 1._o they_o go_v quite_o contrary_a to_o it_o that_o say_v that_o the_o animal_n spirit_n be_v expanded_a and_o the_o pore_n of_o the_o brain_n etc._n etc._n more_o open_a and_o consequent_o more_o lax_n in_o watch_v as_o willis_n and_o several_a other_o who_o therefore_o say_v that_o coffee_n volatile_a salt_n etc._n etc._n be_v antihypnotick_n or_o good_a against_o too_o much_o sleepiness_n because_o they_o cause_v a_o expansion_n of_o the_o spirit_n and_o open_v the_o pore_n of_o the_o brain_n suppose_v forsooth_o that_o they_o march_v up_o and_o down_o and_o so_o keep_v the_o great_a stir_n upon_o the_o false_a imagination_n of_o their_o road_n be_v more_o open_a which_o as_o be_v prove_v be_v real_o more_o close_a coffee_n keep_v we_o from_o sleep_n by_o dry_v bind_a and_o both_o way_n constr_v the_o vessel_n as_o also_o by_o a_o wide_a grate_a quality_n which_o therefore_o do_v irritate_fw-la they_o to_o contract_v beside_o that_o the_o saline_n particle_n cause_v a_o agitation_n may_v contribute_v thereto_o so_o that_o by_o constr_v and_o agitate_v it_o direct_o oppose_v sleep_n which_o proceed_v from_o relaxation_n and_o quietness_n 2._o they_o be_v very_o remote_a from_o the_o mark_n that_o say_v as_o wedeliâ—s_a assert_n all_o do_v that_o vapour_n be_v the_o cause_n of_o natural_a sleep_n which_o bear_v no_o manner_n of_o proportion_n thereto_o as_o be_v show_v as_o they_o be_v also_o who_o mâ—dly_o talk_v that_o the_o animal_n spirit_n which_o have_v neither_o life_n sense_n motion_n or_o election_n do_v of_o themselves_o retire_v very_o know_o to_o the_o brain_n in_o sâ—eep_n and_o leave_v the_o limb_n etc._n etc._n destitute_a of_o they_o whereas_o as_o have_v be_v mechanical_o prove_v they_o have_v more_o room_n than_o that_o at_o other_o time_n in_o 〈◊〉_d limb_n and_o all_o the_o sensile_a part_n but_o i_o will_v not_o argue_v against_o such_o senseless_a and_o precarious_a absurdity_n it_o be_v not_o worth_a the_o while_n especial_o since_o the_o truth_n be_v manifest_o discover_v it_o will_v not_o have_v be_v so_o silly_a to_o have_v affirm_v the_o quite_o contrary_a viz._n that_o the_o animal_n spirit_n be_v force_v into_o the_o soft_a and_o yield_a brain_n in_o watch_v by_o the_o vigilative_a contraction_n of_o all_o the_o senfile_v part_n repel_v they_o as_o when_o cold_a repel_v they_o by_o a_o strong_a contraction_n of_o the_o part_n and_o cause_v a_o stupor_n or_o sleep_n thereof_o as_o they_o call_v it_o but_o what_o have_v we_o to_o do_v with_o such_o insufferable_a trash_n therefore_o bid_v it_o adieu_n let_v we_o pursue_v our_o business_n that_o it_o be_v the_o sensitive_a soul_n and_o nothing_o but_o it_o have_v that_o contract_n power_n be_v evident_a 1._o because_o it_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n as_o such_o and_o that_o nothing_o beside_o it_o have_v any_o life_n perception_n motion_n or_o power_n and_o therefore_o must_v rest_v till_o they_o be_v move_v 2._o because_o that_o when_o the_o sensitive_a soul_n be_v divert_v by_o intense_a pleasure_n from_o attend_v his_o business_n immediate_o relaxation_n follow_v as_o in_o the_o pleasure_n of_o the_o act_n of_o venery_n by_o wine_n joy_n etc._n etc._n in_o which_o you_o have_v all_o the_o effect_n of_o relaxation_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la plentiful_a perspiration_n floridity_n of_o the_o skin_n a_o large_a pulse_n and_o sometime_o a_o considerable_a failure_n of_o sense_n and_o motion_n as_o in_o the_o most_o pleasant_a time_n of_o the_o venereal_a act_n deliquiums_n drunkenness_n syncopes_fw-la or_o ecstasy_n upon_o intense_a pleasure_n which_o be_v very_o proper_o call_v ecstasy_n leipothymy_n leipopsychy_n etc._n etc._n which_o signify_v the_o soul_n leave_v we_o without_o his_o help_n by_o contraction_n which_o he_o then_o do_v not_o exercise_n as_o be_v charm_v and_o whole_o take_v up_o with_o pleasure_n this_o be_v the_o true_a cause_n of_o all_o deliquium_n etc._n etc._n upon_o pleasure_n joy_n etc._n etc._n all_o which_o cause_n great_a relaxation_n and_o thereby_o loss_n of_o sense_n and_o motion_n as_o be_v its_o necessary_a consequence_n 3._o because_o grievous_a sensation_n which_o belong_v only_o to_o the_o sensitive_a soul_n put_v we_o immediate_o out_o of_o sleep_n into_o a_o vigilative_a contraction_n 4._o because_o the_o sensitive_a soul_n can_v when_o we_o be_v sleepy_a oppose_v it_o by_o continue_v the_o vigilative_a contraction_n which_o prove_v vigilative_a contraction_n to_o be_v in_o his_o power_n note_v that_o there_o be_v also_o other_o sort_n of_o leipothymy_n deliquium_n etc._n etc._n upon_o the_o sensitive_a soul_n be_v overtired_n whereof_o natural_a sleep_n be_v but_o a_o common_a and_o ordinary_a degree_n that_o happen_v of_o course_n for_o our_o relief_n or_o overbear_v with_o some_o fatigue_n etc._n etc._n as_o when_o somewhat_o grieve_v at_o stomach_n and_o that_o it_o have_v lay_v about_o it_o all_o manner_n of_o way_n by_o vomit_v convulsive_a motion_n etc._n etc._n to_o be_v rid_v of_o it_o till_o it_o can_v work_v no_o long_o whereupon_o it_o lay_v down_o the_o cudgel_n desi_v from_o all_o further_a endeavour_n by_o contraction_n yield_v itself_o to_o ease_n see_v all_o strive_v be_v to_o no_o effect_n so_o that_o though_o this_o deliquium_fw-la and_o the_o former_a differ_v in_o their_o first_o cause_n yet_o do_v they_o agree_v in_o the_o last_o and_o immediate_a viz._n the_o sensitive_a soul_n be_v not_o attend_v his_o business_n of_o contraction_n whereupon_o follow_v a_o mighty_a relaxation_n as_o appear_v by_o the_o deadness_n or_o relaxation_n of_o the_o cornea_n dilatation_n of_o the_o pupil_n a_o great_a laxity_n of_o all_o part_n a_o large_a pulse_n or_o none_o very_o plentiful_a perspiration_n stop_v of_o hemorrhage_n and_o all_o flux_n that_o require_v contraction_n etc._n etc._n which_o happen_v both_o upon_o the_o account_n of_o the_o great_a relaxation_n itself_o as_o have_v be_v show_v and_o the_o almost_o absolute_a rest_n of_o all_o thing_n by_o the_o sensitive_a soul_n withdraw_a himself_n from_o business_n more_o than_o in_o sleep_n itself_o i_o therefore_o observe_v the_o degree_n of_o sleep_n etc._n etc._n do_v note_n that_o god_n and_o nature_n use_v a_o due_a proportion_n in_o all_o thing_n the_o sensitive_a soul_n use_v several_a degree_n of_o relaxation_n according_a as_o he_o be_v tire_v and_o refection_n be_v want_v hence_o it_o be_v that_o such_o as_o be_v much_o tire_v sleep_n more_o profound_o that_o our_o first_o
by_o squeeze_v in_o some_o case_n and_o stop_v it_o by_o shut_v the_o pore_n in_o other_o case_n 10._o it_o be_v by_o it_o that_o contraction_n that_o fear_v cold_a etc._n etc._n close_v the_o pore_n and_o repel_v the_o blood_n staunch_a bleed_a so_o happen_v also_o a_o great_a contraction_n of_o the_o pupil_n of_o the_o eye_n by_o the_o same_o cause_n 11._o it_o be_v the_o violence_n of_o this_o contraction_n upon_o fear_n terror_n pain_n cold_a etc._n etc._n close_v the_o small_a vessel_n of_o the_o animal_n spirit_n and_o thereby_o repel_v they_o cause_v the_o shiver_a in_o those_o case_n by_o the_o renitency_n of_o the_o elastic_a animal_n spirit_n spring_v back_o again_o toties_fw-la quoties_fw-la have_v gain_v more_o elastic_a force_n by_o the_o very_a compression_n itself_o which_o that_o contraction_n cause_n so_o that_o by_o reason_n of_o the_o dubious_a velitation_n or_o skirmish_v between_o the_o repel_v contraction_n and_o the_o spring_a spirit_n happen_v a_o tremulous_a motion_n as_o of_o quaver_v spring_n which_o shiver_a in_o ague-fits_a do_v former_o lead_v i_o to_o the_o situation_n of_o the_o cause_n of_o ague_n when_o i_o write_v my_o book_n de_fw-fr febribus_fw-la intermittentibus_fw-la in_o the_o angustiae_fw-la at_o the_o end_n of_o the_o vessel_n which_o terminate_v in_o the_o membrane_n the_o grievous_a sensation_n of_o which_o cause_v all_o the_o shiver_a that_o happen_v in_o any_o case_n to_o animal_n 12._o by_o the_o same_o contraction_n when_o very_o violent_a and_o of_o the_o whole_a body_n cold_a sweat_v happen_v in_o pain_n fear_v terror_n etc._n etc._n while_o it_o violent_o squeeze_v out_o the_o outmost_a and_o therefore_o cold_a moisture_n of_o our_o body_n as_o laundress_n do_v water_n out_o of_o wet_a linen_n by_o contortion_n thus_o if_o you_o dip_v one_o half_a of_o a_o wet_a cold_a sheet_n in_o hot_a water_n wrap_v the_o hot_a side_n within_o the_o cold_a or_o let_v a_o warm_a sheet_n that_o be_v contort_a cool_a on_o the_o outside_n of_o it_o and_o then_o wring_v it_o as_o woman_n do_v linen_n the_o water_n that_o first_o exudate_n will_v be_v cold_a for_o in_o this_o case_n the_o close_n of_o the_o pore_n avail_v nothing_o to_o hinder_v it_o as_o long_o as_o the_o express_a force_n master_n it_o more_o especial_o in_o animal_n body_n wherein_o the_o part_n be_v so_o contrive_v that_o humour_n design_v for_o exoretion_n can_v well_o return_v and_o therefore_o must_v upon_o contraction_n run_v out_o hence_o it_o be_v that_o alum_n or_o vitriol_n which_o be_v very_o astringent_a and_o therefore_o close_a the_o pore_n will_v notwithstanding_o cause_v the_o mouth_n or_o nose_n to_o run_v very_o plentiful_o with_o moisture_n by_o contract_v all_o the_o membrane_n about_o the_o mouth_n or_o nose_n and_o thereby_o squeeze_v out_o the_o moisture_n design_v to_o be_v excern_v which_o can_v return_v because_o the_o part_n be_v contrive_v against_o the_o return_n or_o readmittance_n thereof_o whereas_o alum_n or_o vitriol_n will_v staunch_v or_o stop_v blood_n by_o the_o same_o contraction_n because_o it_o may_v return_v as_o not_o be_v design_v to_o be_v excern_v either_o into_o the_o artery_n and_o so_o pass_v by_o other_o branch_n thereof_o or_o which_o be_v more_o ready_a and_o natural_a keep_v its_o course_n into_o the_o vein_n so_o the_o two_o riddle_n that_o i_o have_v know_v some_o proud_a physician_n amaze_v at_o though_o but_o trifle_n of_o alum_n and_o vitriol_n cause_v the_o spital_n etc._n etc._n to_o come_v out_o instead_o of_o stop_v it_o by_o their_o astringency_n and_o their_o stop_a blood_n at_o nose_n at_o the_o same_o time_n they_o cause_v the_o snot_n or_o other_o humour_n to_o run_v out_o be_v unfold_v 13._o it_o be_v by_o this_o mighty_a contraction_n grow_v to_o a_o enormous_a degree_n that_o the_o animal_n spirit_n be_v violent_o compress_v grow_v exceed_o irrequiete_a as_o upon_o convulsion_n in_o great_a pain_n or_o very_o grievous_a sensation_n at_o stomach_n etc._n etc._n while_o the_o sensitive_a soul_n compress_v they_o with_o mighty_a force_n and_o somewhat_o disorderly_a and_o uneven_o because_o of_o the_o confusion_n and_o hurry_n he_o be_v in_o to_o relieve_v the_o animal_n they_o by_o their_o springiness_n fling_v up_o and_o down_o with_o great_a vigour_n this_o make_v convulsive_a motion_n have_v great_a strength_n 14._o the_o body_n under_o this_o contraction_n be_v manifest_o shrink_v by_o measure_n especial_o when_o the_o sensation_n be_v very_o grievous_a but_o most_o of_o all_o if_o they_o cause_v a_o general_a convulsion_n which_o i_o manifest_o observe_v in_o a_o little_a bitch_n that_o be_v convulsive_a all_o over_o for_o three_o hour_n and_o be_v just_a expire_n when_o i_o give_v she_o the_o sal_fw-la volat._n oleo_n of_o opium_n which_o perfect_o restore_v she_o by_o relax_v the_o vessel_n some_o may_v think_v it_o strange_a that_o nature_n shall_v contrive_v a_o more_o nice_a and_o smart_a sensation_n which_o the_o contraction_n of_o the_o vessel_n of_o the_o animal_n spirit_n must_v cause_v by_o compress_v they_o etc._n etc._n in_o pain_n and_o by_o it_o which_o become_v so_o much_o the_o more_o acute_a whereas_o one_o will_v judge_v that_o nature_n will_v rather_o contrive_v its_o ease_n than_o improve_v its_o smart_n you_o be_v to_o know_v that_o the_o pain_n be_v in_o order_n to_o relieve_v the_o animal_n by_o exciting_a all_o its_o power_n to_o defend_v expel_v or_o reject_v the_o cause_n and_o that_o without_o a_o grievous_a sensation_n the_o sensitive_a soul_n be_v neither_o mind_v nor_o excite_v to_o do_v it_o and_o the_o more_o the_o pain_n be_v the_o more_o it_o be_v stir_v up_o to_o self-preservation_n and_o as_o be_v show_v the_o more_o vigorous_a do_v its_o motion_n grow_v by_o the_o compression_n of_o the_o elastic_a spirit_n to_o perform_v that_o work_n so_o nature_n not_o regard_v the_o pain_n which_o be_v rather_o for_o good_a as_o much_o as_o take_v away_o the_o cause_n advance_v that_o for_o this_o purpose_n like_o a_o wise_a physician_n who_o find_v a_o grievance_n at_o stomach_n not_o sufficient_a to_o excite_v effectual_a vomit_v to_o throw_v away_o the_o grieve_v cause_n add_v to_o the_o grievance_n by_o give_v a_o vomit_n which_o because_o as_o be_v say_v nature_n be_v proportionable_o excite_v to_o and_o invigorate_v for_o self-preservation_n sufficient_o solicit_v and_o enable_v it_o by_o a_o strong_a contraction_n to_o reject_v the_o grieve_v matter_n as_o the_o great_a the_o relaxation_n be_v the_o more_o be_v the_o rest_n of_o all_o part_n and_o the_o weak_a the_o animal_n spirit_n because_o less_o compress_v the_o gentle_a be_v all_o motion_n as_o you_o see_v in_o sleep_n consequent_o the_o less_o be_v the_o expense_n of_o spirit_n so_o that_o in_o sleep_n we_o generate_v more_o than_o we_o spend_v and_o be_v thereby_o recruit_v so_o the_o more_o the_o contraction_n be_v the_o more_o violent_a be_v the_o motion_n of_o the_o heart_n intestine_n and_o of_o all_o part_n and_o consequent_o the_o expense_n of_o spirit_n be_v the_o great_a therefore_o it_o can_v be_v no_o wonder_n that_o contraction_n do_v cause_n great_a commotion_n of_o spirit_n diary_n fever_n etc._n etc._n when_o you_o consider_v 1._o that_o the_o sensitive_a soul_n be_v by_o the_o grievous_a sensation_n etc._n etc._n that_o cause_n they_o put_v upon_o a_o great_a fret_v concern_v and_o hurry_v to_o defend_v the_o animal_n and_o lay_v about_o he_o all_o manner_n of_o way_n for_o self-preservation_n 2._o that_o the_o animal_n spirit_n be_v by_o mean_n of_o great_a compression_n cause_v by_o the_o defensive_a contraction_n in_o a_o very_a forcible_a springiness_n which_o cause_v all_o the_o action_n that_o be_v continual_a involuntary_a and_o of_o course_n to_o be_v perform_v with_o great_a violence_n proportionable_a to_o its_o compress_a elasticity_n beside_o that_o 3._o the_o systole_n of_o the_o heart_n be_v oftener_o repeat_v all_o which_o conspire_v to_o cause_v great_a commotion_n upon_o grievous_a sensation_n whereby_o diary_n fever_n etc._n etc._n be_v cause_v which_o be_v easy_o and_o natural_o cure_v by_o sleep_n or_o relaxation_n at_o present_a compose_v and_o quiet_v those_o perturbation_n who_o know_v though_o it_o be_v not_o my_o business_n to_o discuss_v it_o at_o present_a but_o that_o the_o contraction_n in_o the_o cold_a fit_n of_o ague_n have_v a_o great_a hand_n in_o cause_v the_o hot_a one_o how_o otherwise_o shall_v opium_n by_o only_o take_v away_o the_o grievous_a sensation_n of_o the_o cold_a fit_n take_v off_o or_o prevent_v the_o hot_a fit_n also_o but_o of_o this_o in_o my_o often-mentioned_n tract_n though_o not_o so_o often_o as_o it_o grieve_v i_o that_o it_o be_v not_o publish_v how_o reasonable_o may_v we_o now_o expect_v that_o pleasant_a sensation_n may_v cause_v quite_o contrary_a effect_n to_o that_o of_o grievous_a sensation_n viz._n relaxation_n and_o all_o its_o effect_n
which_o be_v a_o shall_v volatile_a oleosum_fw-la and_o thing_n of_o that_o nature_n as_o onion_n garlic_n rocket_n sives_z bear_v garlic_n oyster_n cockle_n shallot_n etc._n etc._n do_v so_o please_v and_o tickle_v the_o venereal_a membrane_n and_o thereby_o excite_v venery_n and_o that_o such_o thing_n be_v general_o so_o very_o agreeable_a to_o the_o stomach_n with_o which_o we_o be_v main_o concern_v as_o the_o chief_a judge_n of_o what_o be_v agreeable_a to_o the_o animal_n and_o so_o main_a ingredient_n of_o relish_v sauce_n etc._n etc._n to_o render_v they_o please_v to_o it_o here_o it_o be_v obvious_a to_o note_v what_o be_v also_o very_o common_o observe_v that_o the_o most_o please_a thing_n to_o the_o stomach_n venereal_a membrane_n etc._n etc._n have_v those_o principle_n more_o active_a warm_a and_o tickle_v than_o the_o membrane_n themselves_o because_o the_o sensitive_a soul_n be_v high_o please_v with_o what_o fine_o actuate_v tickle_v and_o cause_v a_o ovation_n of_o the_o spiritus_fw-la insiti_fw-la of_o the_o membrane_n hence_o bare_a warmth_n be_v so_o very_a please_a as_o be_v also_o gentle_a friction_n of_o the_o head_n back_o etc._n etc._n for_o the_o same_o reason_n 1._o the_o oily_a part_n as_o all_o know_v do_v please_v the_o feel_v with_o which_o we_o have_v to_o do_v by_o their_o smooth_a gentle_a and_o soft_a touch_n thus_o milk_n emulsion_n and_o other_o anodynes_n as_o the_o root_n and_o flower_n of_o water_n lily_n white_a lily_n etc._n etc._n become_v agreeable_a to_o the_o membrane_n and_o theresore_n relax_v and_o ease_v pain_n hence_o it_o be_v that_o all_o aliment_n have_v a_o agreeable_a sweetness_n the_o pleasure_n whereof_o take_v off_o the_o grievous_a sensation_n call_v hunger_n but_o the_o pleasure_n of_o oily_a part_n because_o they_o do_v not_o so_o actuate_v stir_v and_o titillate_v the_o spiritus_fw-la insiti_fw-la be_v but_o flat_a slow_a and_o dull_a without_o they_o be_v join_v with_o some_o other_o particle_n that_o be_v please_v to_o the_o membrane_n that_o actuate_v and_o fine_o titillate_v the_o membrane_n and_o spiritus_fw-la insiti_fw-la therefore_o to_o make_v they_o high_o and_o charm_o please_a they_o shall_v have_v join_v therewith_o 2._o volatile_a salt_n be_v a_o more_o active_a agreeable_a principle_n which_o may_v fine_o and_o pleas_o excite_v actuate_v titillate_v and_o cause_v a_o ovation_n in_o the_o spiritus_fw-la insiti_fw-la as_o onion_n etc._n etc._n at_o stomach_n sem._n animal_n upon_o the_o venereal_a membrane_n etc._n etc._n but_o as_o be_v say_v of_o the_o oily_a part_n that_o they_o can_v cause_v so_o exalt_v a_o pleasure_n without_o the_o volatile_a salt_n so_o the_o volatile_a salt_n alone_o or_o too_o little_a qualify_v and_o smooth_v over_o with_o oily_a part_n be_v too_o rude_a pungent_a or_o acrimonious_a as_o in_o cantharides_n bee_n pismire_n asarabacca_n spearwort_n crowsfoot_o and_o other_o vomitory_n volatiles_fw-la which_o become_v so_o by_o over-stinging_a the_o membrane_n and_o stir_v the_o spiritus_fw-la insiti_fw-la overmuch_o into_o a_o sort_n of_o fury_n instead_o of_o a_o agreeable_a ovation_n it_o follow_v therefore_o that_o it_o be_v neither_o oily_a part_n alone_o which_o if_o too_o much_o often_o nauseate_v the_o stomach_n nor_o volatile_a salt_n alone_o no_o nor_o every_o mixture_n thereof_o but_o a_o certain_a due_a proportion_n of_o both_o so_o as_o to_o have_v the_o volatile_a salt_n somewhat_o more_o predominant_a than_o in_o our_o membrane_n that_o it_o may_v comfortable_o actuate_v titillate_v and_o excite_v our_o spirit_n as_o warmth_n frication_n etc._n etc._n do_v must_v cause_v the_o most_o charm_a and_o exalt_a pleasure_n for_o thing_n exact_o of_o the_o same_o degree_n of_o oil_n and_o volatile_a salt_n with_o our_o membrane_n can_v cause_v but_o a_o slow_a sensation_n because_o they_o make_v little_a or_o no_o alteration_n therein_o which_o be_v one_o of_o the_o great_a requisite_n of_o sensation_n for_o that_o which_o make_v no_o alteration_n as_o the_o saliva_n in_o the_o mouth_n the_o same_o degree_n of_o light_n that_o be_v in_o the_o eye_n of_o sound_z as_o in_o the_o ear_n already_o &c._n &c._n can_v be_v perceive_v because_o where_o no_o difference_n be_v make_v nothing_o can_v be_v perceive_v for_o the_o organ_n be_v affect_v but_o as_o it_o be_v before_o the_o object_n be_v offer_v and_o consequent_o we_o can_v perceive_v that_o any_o new_a thing_n be_v object_v and_o therefore_o can_v be_v at_o all_o sensible_a thereof_o so_o if_o it_o make_v but_o a_o small_a difference_n the_o sensation_n can_v be_v but_o slow_a and_o slight_a proportionable_o as_o of_o a_o little_a degree_n of_o light_n more_o than_o be_v in_o the_o eye_n etc._n etc._n for_o it_o be_v only_o that_o little_a that_o be_v perceive_v for_o as_o be_v notorious_a to_o all_o who_o understand_v any_o thing_n of_o these_o matter_n of_o sensation_n it_o be_v only_o the_o excess_n of_o impression_n to_o what_o be_v upon_o the_o organ_n before_o that_o be_v perceive_v for_o that_o be_v all_o that_o be_v nâ—w_o above_o what_o be_v thereon_o before_o and_o therefore_o all_o that_o be_v to_o be_v or_o can_v be_v perceive_v more_o than_o be_v before_o as_o be_v say_v hence_o it_o be_v that_o flesh_n or_o other_o thing_n that_o have_v the_o salvolatile_a oleosum_fw-la or_o the_o same_o principle_n that_o the_o membrane_n of_o the_o stomach_n venereal_a part_n etc._n etc._n have_v in_o much_o the_o same_o degree_n affect_v they_o but_o with_o a_o gentle_a pleasure_n therefore_o we_o must_v have_v such_o a_o mixture_n wherein_o the_o volatile_a salt_n as_o in_o semine_fw-la animali_fw-la onion_n etc._n etc._n be_v sensible_o more_o active_a than_o in_o our_o membrane_n to_o actuate_v the_o spiritus_fw-la insui_fw-la of_o the_o membrane_n and_o cause_v a_o ovation_n therein_o which_o be_v as_o be_v say_v of_o comfortable_a warmth_n frication_n etc._n etc._n very_o agreeable_a and_o pleasant_a to_o the_o sensitive_a soul_n who_o look_v upon_o such_o as_o friendly_a and_o active_a auxiliary_n to_o our_o spirit_n whereas_o the_o other_o be_v as_o lazy_a friend_n wherein_o he_o take_v not_o the_o like_a complacency_n you_o may_v perceive_v much_o of_o the_o difference_n in_o this_o case_n in_o mustum_n or_o new_o unferment_v wine_n which_o indeed_o do_v lazy_o please_v by_o their_o acceptable_a sweetness_n but_o do_v not_o so_o actuate_v the_o spiritus_fw-la insiti_fw-la as_o the_o same_o oily_a part_n when_o render_v active_a spirituous_a and_o near_o the_o nature_n of_o actual_a heat_n after_o fermentation_n which_o then_o be_v very_o ready_o actuate_v by_o the_o heat_n of_o the_o stomach_n do_v brisk_o and_o cheerful_o return_v the_o kindness_n by_o actuate_a our_o spirit_n and_o put_v they_o into_o a_o please_a ovation_n of_o which_o i_o can_v give_v you_o a_o very_a pat_o and_o pregnant_a instance_n in_o a_o thing_n actuate_v into_o a_o very_a high_a degree_n of_o please_v by_o frication_n and_o agitation_n which_o be_v otherwise_o almost_o insensible_a but_o modesty_n forbid_v i_o note_v how_o the_o sluggish_a oily_a part_n in_o mustum_n do_v by_o be_v spiritualise_v by_o fermentation_n as_o it_o be_v supply_v the_o place_n of_o volatile_a salt_n in_o actuate_a and_o in_o some_o measure_n titillate_v though_o not_o to_o that_o high_a degree_n as_o the_o more_o poignant_a volatile_a salt_n in_o semine_fw-la virili_fw-la and_o the_o like_a because_o the_o sulphureous_a oily_a particle_n however_o separate_v disgregated_a and_o set_v at_o at_o liberty_n by_o fermentation_n retain_v much_o of_o their_o smoothness_n and_o never_o can_v arrive_v at_o the_o titillate_v power_n of_o volatile_a salt_n as_o be_v evident_a in_o amphrodistack_n upon_o the_o account_n of_o volatile_a salt_n as_o cantharides_n bee_n pismire_n etc._n etc._n which_o wine_n in_o 100_o time_n the_o quantity_n can_v equal_v in_o titillation_n nor_o be_v it_o enough_o to_o have_v the_o sal_fw-la volatile_a oleosum_fw-la due_o qualify_v as_o to_o the_o quantity_n and_o quality_n of_o both_o the_o oily_a and_o saline_n part_n and_o these_o predominant_a and_o of_o a_o fine_a brisk_a and_o gentle_o tickle_a activity_n but_o the_o oleous_a and_o salino_n volatile_a part_n shall_v to_o make_v a_o complete_a and_o permanent_a pleaser_n of_o the_o membrane_n be_v very_o intimate_o combine_v so_o as_o not_o easy_o to_o separate_v one_o from_o the_o other_o otherwise_o they_o will_v not_o due_o conspire_v and_o cooperate_v to_o cause_v the_o pleasure_n but_o the_o volatile_a salt_n will_v act_v separately_z as_o such_o that_o be_v irritate_v and_o not_o fine_o and_o pleasant_o tickle_v as_o semen_n humanum_fw-la etc._n etc._n wherein_o the_o oil_n and_o volatile_a salt_n be_v firm_o join_v together_o i_o therefore_o conclude_v that_o the_o most_o excellent_a thing_n to_o please_v the_o membrane_n must_v be_v such_o as_o semen_n humanum_fw-la that_o be_v not_o too_o oily_a for_o then_o it_o will_v not_o sufficient_o please_v by_o a_o fine_a
only_o the_o open_n of_o the_o pore_n so_o that_o i_o need_v add_v no_o more_o word_n about_o it_o for_o the_o fame_n cause_o must_v have_v the_o same_o effect_n therefore_o a_o intense_a and_o permanent_a pleasure_n must_v have_v all_o or_o much_o of_o the_o effect_n of_o sleep_n in_o general_n as_o have_v be_v show_v it_o can_v therefore_o be_v any_o wonder_n that_o opium_n cause_v sleep_n yet_o be_v there_o difference_n between_o sleep_n and_o pleasure_n upon_o other_o account_n though_o not_o upon_o the_o account_n of_o relaxation_n viz._n because_o 1._o that_o sleep_n require_v also_o a_o rest_n of_o spirit_n or_o the_o sensitive_a soul_n whereas_o relaxation_n by_o pleasure_n be_v consistent_a with_o motion_n of_o the_o spirit_n either_o by_o outward_a action_n or_o internal_a motion_n thereof_o by_o some_o inward_a cause_n hence_o it_o be_v first_o that_o we_o can_v labour_v travel_v dance_n etc._n etc._n and_o enjoy_v pleasure_n and_o its_o relaxation_n volantary_a motion_n which_o require_v only_o a_o particular_a contraction_n of_o some_o part_n by_o the_o dictate_v of_o the_o will_n or_o appetite_n be_v consistent_a with_o the_o general_a relaxation_n by_o reason_n of_o the_o prerogative_n of_o the_o will._n thus_o do_v we_o move_v though_o more_o relax_v or_o when_o most_o merry_a and_o please_v with_o wine_n nay_o some_o will_v walk_v in_o their_o sleep_n when_o extreme_o intâ—t_v upon_o a_o thing_n as_o when_o awake_a which_o show_v the_o roll_a power_n of_o intentive_a contraction_n that_o may_v be_v exercise_v with_o relaxation_n and_o other_o contraction_n as_o the_o will_n itself_o may_v or_o intentive_a appetite_n second_o that_o pain_n be_v often_o take_v away_o by_o opium_n by_o the_o diversion_n and_o relaxation_n cause_v by_o pleasure_n and_o its_o inconsistence_n with_o pain_n without_o sleep_n which_o require_v the_o aforesaid_a rest_n that_o bare_a relaxation_n as_o such_o do_v not_o include_v though_o relaxation_n suffice_v to_o take_v away_o pain_n three_o that_o opium_n do_v by_o its_o heat_n active_a particle_n etc._n etc._n hinder_v some_o person_n to_o sleep_n yet_o have_v you_o in_o both_o these_o last_o case_n all_o other_o effect_n of_o opium_n as_o pleasure_n indolence_n relaxation_n etc._n etc._n which_o show_v how_o far_o sleep_v be_v from_o be_v a_o constant_a and_o the_o most_o genuine_a effect_n of_o opium_n as_o be_v general_o imagine_v however_o we_o must_v allow_v it_o as_o have_v be_v show_v to_o be_v a_o mighty_a disposer_n of_o we_o towards_o sleep_n because_o of_o the_o relaxation_n that_o it_o cause_n which_o be_v the_o main_a requisite_a of_o sleep_n ii_o that_o pleasure_n do_v without_o nutritive_a refection_n by_o the_o complacency_n it_o cause_v in_o the_o sensitive_a soul_n produce_v comfort_n satisfaction_n composure_n elevation_n of_o the_o spirit_n euphory_n etc._n etc._n of_o which_o sleep_n be_v either_o not_o at_o all_o capable_a or_o but_o in_o a_o low_a degree_n proportionable_a to_o the_o sensation_n that_o it_o have_v which_o be_v but_o little_a however_o a_o pleasure_n that_o remain_v within_o we_o even_o in_o our_o sleep_n as_o that_o of_o opium_n may_v well_o cause_v pleasant_a dream_n etc._n etc._n the_o reader_n may_v observe_v that_o in_o all_o place_n where_o i_o mention_v that_o relaxation_n cause_v the_o open_n of_o the_o pore_n that_o i_o speak_v only_o of_o perspiration_n as_o the_o effect_n thereof_o without_o mention_v sweat_n 1._o because_o perspiration_n be_v the_o only_a constant_a and_o infallible_a effect_n thereof_o by_o reason_n that_o the_o levity_n of_o the_o fume_n cause_v they_o as_o certain_o to_o pass_v at_o the_o pore_n when_o open_a as_o smoke_n pass_v up_o at_o a_o open_a chimney_n 2._o because_o sweat_n be_v a_o uncertain_a effect_n thereof_o for_o it_o require_v that_o the_o body_n be_v well_o fill_v with_o moisture_n though_o there_o be_v a_o relaxation_n or_o open_v of_o the_o pore_n as_o hypocrates_n very_o right_o intimate_v in_o that_o aphorism_n of_o his_o that_o i_o cite_v in_o the_o last_o chapter_n 1._o because_o sweat_n have_v not_o that_o levity_n that_o the_o fume_n have_v to_o cause_v it_o ready_o to_o move_v as_o soon_o as_o the_o pore_n be_v open_a 2._o because_o relaxation_n be_v more_o apt_a to_o receive_v detain_v and_o suspend_v humour_n 3._o because_o the_o protrusive_a motion_n of_o the_o heart_n be_v weak_a in_o all_o relaxation_n and_o all_o see_v how_o much_o its_o vigorous_a protrusion_n contribute_v to_o sweat_v upon_o action_n 4._o because_o a_o heartful_a of_o blood_n do_v not_o make_v such_o a_o push_v forward_o when_o the_o artery_n be_v widen_v by_o relaxation_n 5._o sweat_n have_v more_o of_o continuity_n consistence_n and_o viscidity_n can_v flow_v out_o so_o ready_o at_o the_o pore_n as_o a_o mere_a vapour_n however_o if_o the_o body_n be_v full_a of_o moisture_n and_o the_o pore_n open_a there_o be_v a_o natural_a course_n that_o way_n and_o the_o heart_n continual_o protrude_a it_o far_o and_o far_o a_o sweat_n follow_v and_o that_o whether_o they_o sleep_v or_o not_o 3._o because_o sweat_v as_o be_v in_o some_o sort_n intimate_v be_v sometime_o cause_v by_o the_o strong_a protrusion_n of_o the_o heart_n as_o in_o motion_n etc._n etc._n and_o upon_o that_o account_n come_v more_o under_o the_o title_n of_o flux_n cause_v by_o contraction_n than_o relaxation_n of_o which_o perspiration_n be_v a_o constant_a effect_n 4._o because_o sweat_n be_v sometime_o cause_v by_o another_o sort_n of_o contraction_n viz._n the_o compression_n of_o the_o whole_a body_n by_o a_o violent_a defensive_a contraction_n as_o in_o great_a terror_n agony_n and_o the_o like_a cause_v thereby_o as_o be_v show_v by_o the_o comparison_n of_o a_o wet_a sheet_n wring_v who_o out_o side_n be_v cold_a a_o cold_a sweat_n which_o that_o of_o alum_n or_o vitriol_n cause_v a_o exudation_n of_o the_o spital_n into_o the_o mouth_n by_o constr_v the_o part_n do_v illustrate_v very_o plain_o therefore_o you_o see_v i_o have_v just_a cause_n not_o to_o mention_v sweat_n as_o a_o certain_a and_o proper_a effect_n of_o relaxation_n without_o good_a distinction_n first_o make_v though_o unwary_a author_n that_o talk_v any_o thing_n one_o after_o another_o not_o know_v what_o they_o say_v make_v it_o their_o common_a say_n that_o sleep_n and_o opium_n stop_v all_o flux_n but_o sweat_n whereas_o they_o shall_v have_v rather_o say_v but_o perspiration_n for_o opium_n and_o sleep_n also_o will_v sometime_o hinder_v sweat_n viz._n that_o from_o pain_n terror_n etc._n etc._n and_o that_o as_o happen_v just_a upon_o awake_v by_o the_o strong_a systole_n of_o the_o heart_n and_o contraction_n of_o the_o whole_a body_n and_o that_o also_o upon_o motion_n unless_o the_o body_n be_v as_o be_v say_v full_a of_o humour_n or_o moisture_n therefore_o it_o be_v a_o vulgar_a error_n to_o say_v sweat_n instead_o of_o perspiration_n in_o the_o case_n aforesaid_a you_o may_v remember_v that_o in_o the_o beginning_n of_o this_o chapter_n i_o conclude_v that_o a_o sal-volatile-oleosum_a such_o as_o semen_n humanum_fw-la wherein_o the_o oily_a and_o volatile_a part_n be_v strict_o combine_v and_o the_o volatile_a somewhat_o more_o active_a or_o acrimonious_a than_o that_o in_o our_o membrane_n in_o general_a must_v be_v most_o please_v to_o the_o membrane_n by_o a_o fine_a titillation_n etc._n etc._n therefore_o if_o opium_n shall_v prove_v to_o be_v such_o we_o need_v not_o wonder_v at_o its_o titillate_v to_o venery_n nor_o indeed_o its_o cause_v a_o high_a sense_n of_o pleasure_n upon_o any_o membrane_n they_o be_v all_o of_o the_o same_o nature_n but_o especial_o upon_o the_o most_o exquisite_o dispose_v membrane_n of_o the_o stomach_n and_o the_o venereal_a part_n nor_o consequent_o its_o cause_v all_o the_o aforementioned_a effect_n of_o intense_a pleasure_n as_o comfort_n satisfaction_n ovation_n etc._n etc._n of_o the_o sensitive_a soul_n or_o spirit_n and_o relaxation_n of_o all_o the_o sensile_a part_n which_o will_v easy_o solve_v all_o the_o phenomenas_n of_o opium_n however_o numerous_a mysterious_a and_o seem_o contradictory_n as_o you_o will_v find_v let_v we_o therefore_o now_o see_v whether_o opium_n be_v such_o a_o sal-volatile-oleosum_a wherein_o the_o volatile_a particle_n be_v somewhat_o more_o active_a or_o acrimonious_a than_o we_o and_o the_o oily_a and_o volatile_a part_n strict_o combine_v if_o so_o the_o business_n be_v do_v the_o nail_n be_v hit_v on_o the_o head_n and_o i_o may_v say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d chap._n xv._o show_v what_o be_v the_o principle_n of_o opium_n and_o which_o cause_n the_o good_a and_o bad_a effect_n thereof_o have_v try_v if_o not_o tire_v your_o patience_n and_o premise_v what_o i_o think_v necessary_a in_o the_o forego_n chapter_n i_o now_o reassume_v the_o thread_n of_o my_o discourse_n as_o for_o the_o passive_a principle_n of_o opium_n which_o do_v or_o signify_v little_a or_o nothing_o
by_o titillation_n upon_o the_o account_n of_o the_o volatile_a salt_n which_o appear_v by_o its_o exciting_a to_o venery_n at_o the_o same_o time_n as_o all_o those_o volatiles_fw-la do_v 16._o it_o be_v cause_v vomit_n as_o it_o often_o do_v be_v a_o undoubted_a sign_n of_o its_o volatile_a salt_n for_o all_o vegetable_a vomit_n be_v such_o upon_o that_o account_n unless_o it_o be_v such_o as_o may_v move_v vomit_v mere_o by_o their_o be_v loathe_v or_o nauseated_a which_o only_o cause_v some_o particular_a person_n to_o vomit_v but_o such_o as_o be_v constant_a vomitory_n be_v so_o upon_o the_o account_n of_o their_o volatile_a salt_n as_o asaerabocea_n groundsil_n foxâ—loves_n squill_n etc._n etc._n give_v in_o a_o sufficient_a quantity_n 17._o it_o be_v lively_a effect_n as_o courage_n etc._n etc._n prove_v the_o same_o 18._o all_o author_n that_o have_v be_v curious_a do_v agree_v that_o opium_n abound_v with_o volatile_a salt_n as_o helmont_n lemery_n le_fw-fr febure_n wedelius_n and_o indeed_o every_o one_o that_o ever_o i_o read_v though_o most_o of_o they_o attribute_v its_o effect_n to_o a_o sulphur_n which_o make_v their_o testimony_n of_o its_o volatile_a salt_n the_o strong_a as_o be_v force_v to_o confess_v it_o against_o their_o hypothesise_n 19_o after_o its_o fermentation_n with_o leaven_n in_o a_o sand_n heat_v for_o 14_o day_n it_o afford_v a_o volatile_a salt_n in_o good_a quantity_n but_o mix_v with_o oil_n which_o be_v separate_v from_o it_o by_o dissolution_n in_o water_n filtring_n etc._n etc._n 20._o it_o be_v spirit_n ferment_n with_o acid_n therefore_o be_v volatile_a last_o to_o pin_n up_o all_o if_o you_o either_o chemical_o analyse_v it_o by_o fire_n or_o set_v it_o to_o crystalize_v after_o it_o be_v evaporate_v to_o a_o due_a condition_n so_o to_o do_v it_o afford_v a_o great_a quantity_n of_o volatile_a salt_n therefore_o it_o be_v pass_v all_o manner_n of_o doubt_n for_o which_o end_n i_o have_v the_o long_o and_o more_o particular_o insist_v upon_o this_o point_n that_o it_o be_v high_o impregnate_v with_o volatile_a salt_n but_o as_o i_o say_v in_o the_o last_o chapter_n it_o be_v not_o enough_o for_o it_o to_o have_v volatile_a salt_n but_o it_o must_v be_v such_o as_o exceed_v our_o own_o or_o other_o animal_n in_o activity_n briskness_n etc._n etc._n by_o reason_n of_o quantity_n or_o quality_n or_o both_o that_o it_o may_v tickle_v up_o excite_v and_o cause_v a_o fine_a and_o agreeable_a ovation_n or_o glow_v in_o our_o spirit_n which_o as_o be_v show_v be_v very_o pleasant_a as_o in_o the_o case_n of_o sem._n viril_n especial_o when_o agitate_a by_o warmth_n frication_n or_o such_o actuate_a cause_n second_o it_o manifest_o appear_v that_o the_o volatile_a salt_n of_o opium_n exceed_v we_o in_o activity_n briskness_n etc._n etc._n 1._o by_o its_o exulcerate_v or_o blister_v quality_n especial_o if_o it_o be_v very_o good_a opium_n 2._o by_o its_o psilothrick_n quality_n to_o cause_v the_o hair_n to_o shed_v 3._o by_o its_o irritate_v to_o venery_n in_o so_o eminent_a a_o degree_n as_o cantharides_n bee_n pismire_n etc._n etc._n do_v and_o even_o beyond_o the_o ordinary_a course_n of_o sem._n virile_a which_o be_v most_o saturate_v with_o volatile_a salt_n of_o any_o part_n of_o the_o animal_n as_o appear_v by_o its_o dissolution_n like_o opium_n in_o watery_a menstruum_n its_o rank_a smell_n its_o titillate_v to_o venery_n its_o weight_n etc._n etc._n which_o be_v much_o the_o same_o with_o that_o of_o opium_n both_o sink_v in_o water_n etc._n etc._n 4._o by_o its_o great_a irritation_n to_o make_v water_n like_o cantharides_n bee_n pismire_n millepedes_n etc._n etc._n when_o it_o be_v take_v in_o a_o good_a quantity_n or_o often_o 5._o by_o its_o cause_v vomit_n in_o a_o very_a severe_a manner_n which_o it_o will_v not_o do_v without_o a_o very_a poignant_a volatile_a salt_n 6._o by_o its_o cause_v such_o violent_a itch_n in_o the_o skin_n especial_o if_o take_v in_o any_o quantity_n after_o it_o have_v pass_v all_o digestion_n and_o concoction_n and_o 7._o by_o its_o cause_v acrimonious_a sweat_v after_o it_o have_v pass_v those_o digestion_n and_o concoction_n 8._o by_o its_o cause_v a_o very_a pleasant_a sensation_n at_o stomach_n far_o above_o any_o flesh_n jelly_n or_o any_o animal_n nutriment_n 9_o by_o its_o offend_v the_o eye_n so_o much_o by_o its_o acrimony_n as_o mustard_n onion_n horse_n radish_n etc._n etc._n do_v 10._o by_o its_o very_a pungent_a and_o acrimonious_a taste_n above_o all_o flesh_n or_o fish_n 11._o by_o its_o very_a rank_n and_o vehement_a scent_n equal_a to_o if_o not_o exceed_v that_o of_o semen_n virile_a 12._o by_o its_o chemical_a analysis_n whereby_o it_o afford_v a_o very_a acrimonious_a volatile_a salt_n in_o great_a plenty_n which_o helmont_n wedelius_n and_o other_o do_v confirm_v therefore_o it_o be_v also_o past_a doubt_n that_o the_o volatile_a salt_n of_o opium_n be_v more_o active_a acrimonious_a and_o titillate_v than_o those_o in_o our_o membrane_n or_o in_o sem._n virile_a itself_o but_o see_v it_o be_v not_o volatile_a salt_n alone_o as_o be_v show_v which_o agree_v only_o with_o one_o of_o the_o active_a principle_n of_o our_o membrane_n and_o may_v be_v and_o be_v of_o itself_o too_o acrimonious_a and_o rude_a for_o the_o membrane_n without_o its_o be_v sweeten_v up_o and_o smooth_v into_o a_o more_o gentle_a and_o please_a agreeableness_n by_o oily_a part_n we_o must_v see_v whether_o it_o be_v not_o also_o oily_a or_o sulphureous_a and_o consequent_o a_o sal-volatile-oleosum_a agree_v in_o both_o the_o active_a principle_n of_o our_o membrane_n that_o it_o may_v thereby_o be_v the_o more_o delectable_a gentle_a and_o agreeable_a three_o it_o be_v very_o obvious_a and_o evident_a that_o opium_n be_v sulphureous_a 1._o because_o the_o juice_n of_o the_o poppy_n whereof_o it_o be_v make_v be_v of_o itself_o when_o it_o drop_n out_o of_o the_o incision_n milkwhite_a which_o colour_n in_o liquid_n especial_o the_o juice_n of_o plant_n proceed_v from_o sulphureous_a particle_n mix_v with_o water_n or_o phlegm_n as_o milk_n emulsion_n chyle_n cinnamon_n water_n and_o the_o tincture_n of_o all_o sulphureous_a thing_n drop_v into_o water_n do_v evince_n 2._o because_o it_o be_v inflammable_a for_o nothing_o be_v so_o but_o what_o be_v sulphureous_a 3._o because_o opium_n will_v soften_v with_o a_o dry_a warmth_n which_o all_o and_o only_o sulphureous_a thing_n will_v do_v as_o all_o rosin_n tallow_n pitch_v turpentine_n oil_n and_o such_o sulphureous_a thing_n 4._o because_o it_o be_v very_o bitter_a and_o that_o oleose_a particle_n be_v always_o as_o dr._n grow_v and_o silvius_n true_o say_v one_o ingredient_n of_o a_o bitter_a taste_n 5._o it_o be_v tawny_a colour_n do_v also_o as_o be_v say_v according_a to_o dr._n grow_v argue_v much_o sulphur_n 6._o it_o be_v hot_a taste_n prove_v the_o same_o for_o a_o proper_a hot_a taste_n be_v from_o sulphur_n as_o the_o bite_n or_o pungent_a be_v from_o volatile_a salt_n 7._o because_o of_o its_o pungent_a and_o strong_a smell_n which_o denote_v sulphur_n 8._o it_o be_v be_v so_o dissolvable_a as_o it_o be_v in_o spirit_n of_o wine_n brandy_n and_o other_o sulphureous_a menstruum_n prove_v the_o same_o 9_o it_o be_v dissolve_v quality_n argue_v that_o it_o have_v the_o same_o principle_n with_o our_o skin_n and_o flesh_n which_o be_v oleose_v as_o well_o as_o salino-volatile_a and_o that_o nothing_o be_v a_o complete_a dissolver_n but_o such_o as_o have_v both_o because_o agreeableness_n in_o principle_n be_v the_o basis_n of_o dissolution_n as_o you_o see_v in_o menstruum_n and_o the_o thing_n therein_o dissolve_v there_o be_v no_o good_a kind_a or_o complete_a dissolvent_a of_o our_o flesh_n etc._n etc._n but_o what_o participate_v of_o both_o because_o otherwise_o there_o will_v be_v a_o disagreement_n in_o one_o respect_n 10._o it_o appear_v by_o autopsie_n upon_o the_o chemical_a analysis_n of_o opium_n etc._n etc._n that_o it_o have_v a_o very_a considerable_a quantity_n of_o sulphur_n 11._o so_o if_o you_o only_o dissolve_v it_o in_o water_n you_o will_v find_v much_o sulphureous_a substance_n undissolved_a at_o the_o bottom_n 12._o all_o or_o most_o of_o the_o modern_a author_n attribute_v its_o operation_n to_o sulphur_n agree_v that_o it_o be_v well_o impregnate_v therewith_o therefore_o opium_n consist_v very_o much_o as_o to_o its_o active_a principle_n of_o a_o sal-volatile-sulphureum_a but_o still_o this_o do_v not_o complete_a a_o most_o agreeable_a sal-volatile-oleosum_a 1._o because_o it_o may_v be_v a_o sal-volatile-resinosum_a and_o yet_o be_v a_o sal-volatile-sulphureum_a 2._o if_o it_o be_v a_o sal-volatile-oleosum_a the_o oil_n and_o the_o volatile_a salt_n may_v be_v so_o disjoin_v as_o not_o to_o conspire_v and_o cooperate_v to_o please_v the_o membrane_n but_o act_n separately_z as_o oil_n and_o volatile_a salt_n give_v out_o of_o divers_a
spoon_n and_o cause_n no_o more_o effect_n than_o oil_n of_o olive_n and_o spirit_n of_o sal_fw-la amenoniack_a take_v inward_o one_o act_v too_o soft_o lazy_o and_o greasy_o to_o cause_v any_o brisk_a and_o agreeable_a ovation_n of_o the_o spirit_n and_o the_o other_o too_o rude_o sting_v the_o membrane_n therefore_o we_o must_v proceed_v in_o our_o enquiry_n four_o opium_n have_v a_o sort_n of_o resinous_n sulphur_n that_o be_v loose_a and_o not_o unite_v with_o the_o volatile_a salt_n which_o plain_o appear_v 1._o because_o if_o you_o dissolve_v opium_n in_o water_n cold_a or_o hot_a or_o any_o watery_a menstruum_fw-la you_o will_v find_v a_o good_a quantity_n of_o rosin_n undissolved_a at_o bottom_n while_o the_o volatile_a salt_n be_v all_o or_o most_o dissolve_v in_o the_o water_n especial_o if_o the_o water_n be_v often_o repeat_v and_o quite_o separate_v from_o the_o resinous_n part_v which_o subside_v without_o any_o more_o trouble_n which_o show_v that_o the_o volatile_a salt_n and_o it_o be_v not_o combine_v but_o in_o a_o very_a loose_a and_o distinct_a manner_n 2._o because_o if_o you_o first_o dissolve_v opium_n in_o spirit_n of_o wine_n which_o imbibe_v the_o rosin_n it_o be_v easy_o again_o precipitate_v by_o plain_a water_n leave_v behind_o it_o all_o or_o most_o of_o the_o volatile_a salt_n in_o the_o form_n of_o a_o red_a tincture_n in_o the_o menstruum_fw-la as_o it_o do_v also_o in_o the_o former_a case_n note_v that_o the_o resinous_n part_n of_o opium_n have_v no_o effect_n as_o a_o opiate_n for_o if_o it_o be_v well_o wash_v with_o water_n as_o be_v say_v it_o have_v no_o operation_n of_o that_o kind_n or_o so_o little_a that_o it_o be_v not_o worth_a the_o mind_v but_o all_o the_o virtue_n specific_a taste_n smell_v etc._n etc._n be_v carry_v away_o in_o that_o red_a tincture_n which_o have_v all_o the_o good_a effect_n of_o opium_n as_o experience_n assure_v we_o 3._o because_o if_o opium_n be_v very_o much_o torrefy_v most_o of_o the_o volatile_a salt_n be_v evaporate_v and_o with_o it_o most_o if_o not_o all_o the_o virtue_n of_o opium_n but_o the_o rosin_n remain_v as_o a_o deadish_a stuff_n in_o respect_n of_o the_o good_a effect_n of_o opium_n though_o it_o be_v as_o shall_v be_v prove_v the_o producer_n of_o the_o ill_a effect_n thereof_o therefore_o this_o rosin_n must_v be_v whole_o reject_v five_o the_o red_a tincture_n aforesaid_a have_v all_o or_o most_o of_o the_o volatile_a salt_n in_o it_o 1._o because_o water_n be_v the_o proper_a menstruum_fw-la for_o saline_n thing_n and_o that_o the_o tincture_n reduce_v to_o a_o extract_n give_v very_o much_o in_o moist_a wether_n which_o quality_n it_o must_v have_v from_o the_o volatile_a salt_n because_o it_o have_v very_o little_o fix_v salt_n 2._o because_o the_o specific_a bitterness_n which_o proceed_v from_o volatile_a salt_n and_o oily_a part_n be_v whole_o in_o that_o red_a tincture_n 3._o because_o that_o tincture_n have_v also_o the_o specific_a rankness_n of_o smell_n that_o the_o volatile_a salt_n as_o be_v show_v give_v the_o opium_n by_o the_o help_n of_o some_o oily_a part_n 4._o because_o that_o tincture_n reduce_v to_o a_o extract_n have_v the_o bite_a taste_n of_o opium_n which_o as_o be_v show_v proceed_v from_o its_o volatile_a salt_n 5._o because_o that_o extract_n incides_fw-la discuss_n resolve_n be_v psilothrick_n titillate_n to_o venery_n cause_v itch_n in_o the_o skin_n acrimonious_a sweat_v etc._n etc._n all_o which_o be_v as_o be_v show_v the_o effect_n of_o volatile_a salt_n but_o what_o need_v i_o insist_v so_o much_o upon_o its_o effect_n to_o prove_v it_o when_o 6._o it_o appear_v by_o crystalization_n of_o the_o say_a tincture_n after_o it_o have_v be_v evaporate_v to_o a_o due_a degree_n that_o it_o contain_v the_o volatile_a salt_n in_o it_o which_o in_o a_o cool_a place_n shoot_v to_o elegant_a crystal_n and_o that_o 7._o it_o be_v find_v therein_o by_o chemical_a operation_n by_o fire_n six_o the_o say_a tincture_n be_v oleose_v 1._o because_o the_o redness_n of_o the_o tincture_n must_v be_v from_o oily_a part_n for_o pure_a sincere_a volatile_a salt_n give_v no_o such_o tincture_n 2._o because_o it_o be_v bitter_a one_o ingredient_n of_o which_o taste_n be_v ever_o oily_a part_n as_o be_v say_v 3._o because_o of_o its_o rank_a smell_n like_o sem._n viril_n which_o prove_v it_o to_o be_v sulphureous_a for_o the_o volatile_a salt_n alone_o have_v only_o a_o quick_a smell_n or_o urinous_a at_o far_a 4._o because_o it_o be_v of_o a_o hot_a taste_n when_o reduce_v to_o a_o extract_n which_o heat_v of_o taste_n consider_v distinct_o from_o its_o pungent_a or_o bite_a taste_n must_v be_v from_o sulphureous_a or_o oily_a part_n 5._o because_o spirit_n of_o wine_n and_o other_o spirituosulphureous_a menstruum_n do_v ready_o dissolve_v it_o when_o reduce_v to_o a_o extract_n 6._o because_o the_o extract_n soften_v with_o dry_a warmth_n as_o sulphureous_a or_o oily_a thing_n do_v 7._o because_o a_o true_a sal-volatile-oleosum_a wherein_o the_o volatile_a salt_n and_o oily_a part_n be_v intimate_o combine_v as_o you_o find_v in_o all_o blood_n tincture_n of_o several_a plant_n that_o have_v such_o a_o sal-volatile-oleosum_a be_v red_a 8._o because_o it_o can_v not_o otherwise_o so_o fine_o please_v the_o membrane_n cause_n sleep_n compose_v the_o spirit_n etc._n etc._n if_o it_o be_v all_o volatile_a salt_n which_o be_v whole_o pungent_a and_o acrimonious_a mighty_o oppose_v sleep_n and_o cause_v a_o great_a stir_n in_o the_o blood_n and_o spirit_n but_o as_o i_o say_v as_o to_o its_o volatile_a salt_n what_o need_v i_o insist_v upon_o its_o effect_n when_o 10._o it_o be_v inflammability_n after_o it_o be_v reduce_v to_o a_o extract_n and_o dry_v put_v it_o out_o of_o all_o question_n and_o that_o 11._o a_o oil_n may_v be_v separate_v from_o the_o volatile_a salt_n though_o not_o without_o trouble_n because_o that_o as_o be_v requisite_a to_o complete_a it_o in_o the_o high_a degree_n seven_o the_o oily_a part_n and_o volatile_a salt_n be_v very_o intimate_o and_o strict_o combine_v as_o fair_o appear_v 1._o by_o the_o difficulty_n to_o separate_v they_o 2._o by_o the_o redness_n of_o the_o tincture_n as_o in_o blood_n etc._n etc._n for_o when_o oily_a or_o sulphureous_a particle_n be_v loose_a therein_o they_o make_v either_o a_o white_a colour_n as_o the_o rosin_n do_v in_o the_o drop_n that_o fall_v out_o of_o the_o incision_n in_o the_o head_n of_o the_o poppy_n which_o be_v milk_n white_a or_o leave_v the_o volatile_a spirit_n perspicuous_a as_o in_o a_o sort_n of_o artificial_a sal._n volatile-oleosum_a that_o be_v sell_v at_o the_o apothecary_n shop_n in_o london_n 3._o because_o it_o impart_v its_o tincture_n which_o depend_v upon_o both_o to_o all_o menstruum_n 4._o because_o it_o impart_v its_o virtue_n which_o depend_v upon_o both_o to_o all_o menstruum_n 5._o because_o it_o impart_v its_o specific_a smell_n which_o depend_v upon_o both_o to_o all_o menstruumt_v 6._o because_o it_o impart_v its_o specific_a hot_a and_o bite_a taste_n which_o depend_v upon_o both_o the_o oily_a and_o volatile_a particle_n to_o all_o menstruum_n 7._o because_o it_o will_v hold_v its_o virtue_n many_o year_n which_o it_o can_v not_o if_o the_o volatile_a salt_n and_o oily_a part_n be_v not_o very_o strict_o combine_v 8._o because_o that_o notwithstanding_o the_o digestion_n at_o stomach_n it_o have_v hold_v its_o specific_a virtue_n smell_v and_o taste_n after_o it_o have_v be_v in_o it_o 4_o 5_o 6_o 7_o 8_o 9_o 10_o 11_o 12_o 18_o or_o more_o hour_n as_o appear_v by_o its_o operate_n so_o long_o and_o afteward_n its_o be_v vomit_v up_o with_o the_o same_o taste_n and_o smell_v that_o it_o have_v at_o first_o than_o which_o there_o can_v be_v a_o great_a argument_n 9_o because_o it_o have_v be_v carry_v off_o by_o stool_n which_o have_v its_o specific_a smell_n after_o many_o hour_n remain_v in_o the_o stomach_n 10._o because_o its_o operation_n in_o general_n last_v long_o charas_fw-la mention_n one_o that_o it_o operate_v with_o for_o about_o 30_o hour_n and_o wedelius_n another_o who_o opium_n cause_v to_o vomit_v constant_o about_o 18_o hour_n after_o it_o be_v take_v 11._o because_o it_o have_v its_o effect_n upon_o the_o venereal_a membrane_n after_o it_o have_v pass_v the_o digestion_n at_o stomach_n the_o effect_n of_o the_o choler_n and_o succus_fw-la pancreatus_fw-la in_o the_o duodenum_fw-la be_v strain_v through_o the_o coat_n of_o the_o intestine_n into_o the_o lacteal_v and_o through_o the_o glandule_n of_o the_o mesentery_n mix_v and_o circulate_v with_o the_o blood_n etc._n etc._n 12._o because_o after_o all_o that_o it_o have_v its_o effect_n upon_o the_o skin_n by_o cause_v a_o itch_a therein_o 13._o because_o it_o not_o only_a cause_n acrimonious_a sweat_v but_o such_o as_o evident_o smell_v thereof_o
be_v repute_v opiate_n borellus_n speak_v of_o a_o soporiferous_a aura_n that_o proceed_v from_o one_o thumb_n cure_v by_o a_o caustick_a i_o have_v read_v of_o a_o cataphora_fw-it from_o worm_n a_o soporiferous_a fume_v from_o the_o womb_n and_o very_o many_o such_o sort_n of_o instance_n which_o thing_n be_v now_o easy_o conceive_v for_o it_o be_v but_o suppose_v a_o fume_v of_o the_o nature_n of_o sem._n animale_a or_o its_o aura_n for_o i_o can_v no_o long_o doubt_v but_o it_o be_v a_o opiate_n and_o it_o will_v have_v much_o the_o same_o effect_n with_o opium_n if_o it_o be_v fit_a to_o use_v it_o after_o the_o same_o manner_n have_v show_v 1._o which_o be_v the_o predominant_a active_a principle_n in_o opium_n and_o how_o combine_v etc._n etc._n 2._o which_o of_o they_o produce_v the_o usual_a and_o laudable_a effect_n of_o opium_n and_o why_o in_o general_a i_o come_v now_o to_o the_o three_o particular_a viz._n to_o show_v iii_o which_o of_o they_o produce_v its_o ill_a effect_n and_o why_o it_o be_v ill_a effect_n be_v these_o viz._n nauseas_fw-la vomit_n which_o be_v general_o very_o dismal_a with_o great_a distress_n and_o sometime_o dangerous_a swim_v in_o the_o head_n hiccough_n distress_n anxiety_n convulsion_n faint_n leipothymy_n syncopes_fw-la etc._n etc._n 1._o note_v that_o its_o grievous_a effect_n be_v at_o or_o about_o the_o region_n of_o the_o stomach_n or_o particular_o the_o mouth_n or_o pit_n thereof_o or_o thence_o arise_v by_o consent_n 2._o note_v that_o see_v there_o be_v nothing_o so_o good_a but_o may_v cause_v evil_a effect_n in_o a_o excessive_a quantity_n this_o enquiry_n be_v more_o proper_o what_o principle_n or_o principle_n of_o opium_n do_v cause_n those_o ill_a effect_n in_o a_o ordinary_a do_v for_o what_o will_v in_o a_o moderate_a do_v will_v be_v sure_a cause_v they_o in_o a_o excessive_a do_v 3._o note_v that_o all_o the_o constant_a effect_n of_o opium_n as_o you_o may_v observe_v in_o the_o enumeration_n thereof_o in_o the_o four_o chapter_n be_v good_a and_o laudable_a effect_n it_o follow_v therefore_o that_o the_o bad_a be_v accidental_a 1._o it_o be_v not_o the_o earthy_a or_o phlegmatic_a part_n of_o opium_n that_o cause_v those_o ill_a effect_n because_o they_o be_v passive_a principle_n and_o consequent_o have_v not_o such_o a_o power_n beside_o that_o they_o be_v know_v to_o be_v innocent_a 2._o opium_n have_v all_o those_o ill_a effect_n when_o both_o the_o earthy_a and_o phlegmatic_a part_n be_v separate_v from_o it_o as_o when_o a_o extract_v of_o well_o torrefy_v opium_n be_v make_v in_o spirit_n of_o wine_n for_o by_o that_o mean_v the_o phlegmatic_a part_n be_v dry_v up_o and_o the_o earthy_a part_n subside_o and_o be_v separate_v yea_o such_o extract_v make_v by_o spirit_n of_o wine_n do_v cause_n those_o evil_a effect_n rather_o more_o than_o crude_a opium_n with_o its_o earth_n and_o phlegm_n in_o it_o as_o experience_n assure_v we_o and_o reason_n will_v plain_o confirm_v by_o and_o by_o however_o fond_a the_o world_n be_v of_o such_o preparation_n 3._o it_o be_v evident_a from_o the_o premise_n that_o the_o sal-volatile-oleosum_a of_o opium_n can_v cause_v those_o vomit_n hiccough_n etc._n etc._n for_o they_o be_v the_o effect_n of_o grievous_a sensation_n at_o stomach_n but_o the_o sal-volatile-oleosum_a cause_n a_o most_o agreeable_a and_o please_a sensation_n at_o stomach_n 4._o nothing_o quiet_v vomit_n convulsion_n â—coughs_n etc._n etc._n more_o than_o that_o sal-volatile-oleosum_a of_o opium_n 5._o experience_n inform_v we_o that_o the_o sal-volatile-oleosum_a of_o opium_n separate_v from_o all_o other_o part_n and_o principle_n thereof_o never_o cause_v such_o evil_a effect_n as_o i_o and_o another_o physician_n in_o london_n can_v testify_v as_o do_v also_o le_fw-fr mort_fw-fr in_o the_o most_o learned_a dr._n love_n collectanea_fw-la where_o he_o say_v of_o such_o a_o preparation_n thereof_o as_o contain_v only_o the_o sal-volatile-oleosum_a that_o nunquam_fw-la anxietates_fw-la circa_fw-la praecordia_fw-la aut_fw-la phantasias_fw-la conciliat_fw-la that_o be_v it_o never_o cause_v anxiety_n about_o the_o mouth_n of_o the_o stomach_n etc._n etc._n for_o that_o be_v most_o proper_o to_o be_v understand_v by_o praecordia_fw-la wedelius_n testify_v the_o like_a of_o such_o another_o preparation_n and_o so_o do_v several_a author_n though_o they_o do_v not_o in_o the_o least_o know_v why_o but_o only_o by_o experience_n 6._o it_o be_v fix_v salt_n be_v innocent_a in_o its_o nature_n and_o but_o the_o 32d_o part_n of_o opium_n which_o be_v too_o inconsiderable_a in_o a_o ordinary_a moderate_a do_v to_o cause_v any_o sensible_a effect_n it_o follow_v therefore_o that_o be_v must_v be_v the_o resinous_n part_n of_o opium_n which_o it_o have_v in_o a_o considerable_a quantity_n that_o must_v cause_v those_o ill_a effect_n this_o manifest_o appear_v 1._o because_o a_o tincture_n of_o opiam_fw-la in_o water_n which_o take_v up_o none_o of_o the_o rosin_n but_o let_v it_o fall_v into_o the_o bottom_n never_o cause_v any_o such_o ill_a effect_n which_o it_o do_v not_o also_o if_o reduce_v to_o a_o extract_v by_o evaporation_n yet_o have_v they_o all_o the_o usual_a good_a effect_n of_o opium_n 2._o wedelius_n in_o his_o opiolog_n assure_v the_o same_o of_o the_o like_a preparation_n in_o phlegm_n of_o distil_a vinegar_n l._n 2._o sect._n 1_o c._n 5._o p._n 92._o 3._o a_o extract_v of_o opium_n in_o spirit_n of_o wine_n do_v often_o cause_v those_o ill_a effect_n and_o no_o other_o preparation_n cause_v they_o as_o often_o wedelius_n ibid._n a_o laudano_n opiato_fw-it cum_fw-la spiritu_fw-la vini_n correcto_fw-la solum_fw-la ferâ—_n observavimus_fw-la ortos_fw-la vomitus_fw-la a_o nostro_fw-la vero_fw-la quod_fw-la cum_fw-la phlegmate_fw-it aceti_fw-la distillati_fw-la fieri_fw-la diximus_fw-la nunquam_fw-la vomitum_fw-la vel_fw-la nauseam_fw-la saltem_fw-la contigisse_fw-la meminimus_fw-la that_o be_v we_o have_v observe_v vomit_n almost_o only_o from_o laudanum_n prepare_v with_o spirit_n of_o wine_n but_o never_o any_o vomit_v or_o nausea_n from_o that_o prepare_v in_o phlegm_n of_o distil_a vinegar_n which_o he_o confirm_v l._n 1._o sect_n 2._o c._n 4._o p._n 62._o saying_n in_o latin_a that_o a_o curious_a observation_n be_v to_o be_v note_v by_o which_o it_o appear_v that_o a_o extract_v of_o opium_n with_o spirit_n of_o wine_n show_v more_o narcotick_a force_n by_o which_o he_o mean_v that_o it_o cause_v more_o ill_a effect_n than_o prepare_v in_o distil_a vinegar_n whereas_o that_o in_o spirit_n of_o wine_n have_v nothing_o more_o in_o it_o than_o that_o in_o vinegar_n beside_o the_o râ—sinous_n part_n therefore_o these_o do_v cause_n all_o the_o mischief_n note_v also_o that_o a_o extract_v in_o spirit_n of_o wine_n have_v in_o it_o quantity_n for_o quantity_n more_o of_o the_o râ—sinous_n part_v than_o crude_a oplum_fw-la both_o because_o the_o earthy_a part_n that_o help_v to_o make_v up_o the_o bulk_n be_v take_v away_o in_o that_o preparation_n and_o because_o the_o 〈◊〉_d of_o wine_n imbibe_v the_o rosin_n more_o greedy_o than_o other_o principle_n of_o the_o opium_n so_o that_o every_o do_v must_v in_o proportion_n have_v much_o more_o rosin_n in_o it_o than_o crude_a opium_n therefore_o it_o be_v no_o wonder_n that_o it_o cause_v those_o ill_a effect_n more_o frequent_o since_o the_o rosin_n be_v most_o certain_o the_o cause_n thereof_o as_o have_v be_v and_o shall_v be_v more_o full_o and_o beyond_o all_o contradiction_n prove_v yet_o be_v this_o the_o preparation_n boast_v of_o by_o the_o blind_a and_o inadvertent_n world_n it_o will_v amaze_v nay_o terrify_v a_o man_n to_o see_v what_o great_a care_n be_v take_v to_o be_v sure_a to_o render_v opium_n mischievous_a by_o solicitous_o use_v spirit_n of_o wine_n in_o extract_a laudanum_n and_o then_o and_o not_o till_o then_o they_o boast_v of_o the_o preparation_n as_o charas_fw-la and_o very_o many_o other_o do_v calling_z it_o not_o without_o great_a ostentation_n and_o desperate_a folly_n their_o laudanum_n may_v it_o be_v they_o and_o none_o other_o a_o turk_n will_v be_v a_o madman_n to_o use_v it_o for_o crude_a opium_n because_o it_o have_v much_o more_o of_o the_o pernicious_a principle_n in_o it_o it_o be_v the_o common_a and_o much_o esteem_v way_n first_o to_o extract_v it_o out_o of_o water_n and_o then_o it_o be_v very_o good_a laudable_a and_o innocent_a but_o think_v nothing_o worth_a till_o they_o extract_v the_o rosin_n that_o be_v all_o leave_v behind_o by_o the_o water_n in_o spirit_n of_o wine_n and_o add_v it_o to_o the_o other_o then_o do_v they_o with_o great_a authority_n praise_v it_o that_o be_v when_o they_o have_v wise_o add_v the_o poison_n to_o the_o panacea_fw-la it_o be_v as_o if_o they_o add_v ratsbane_n to_o a_o cordial_n and_o not_o think_v the_o cordial_a worthy_a commendation_n till_o they_o have_v do_v so_o 4._o it_o appear_v that_o the_o rosin_n be_v
only_o in_o those_o membrane_n but_o also_o in_o the_o more_o exquisite_o dispose_v membrane_n for_o sensation_n at_o stomach_n and_o soon_o after_o all_o over_o the_o body_n 5._o it_o prevent_v and_o take_v away_o grief_n fear_v anxiety_n peevishness_n fretfulness_n etc._n etc._n for_o the_o aforesaid_a reason_n which_o cause_n a_o blithe_a gay_a and_o good_a humour_n promptitude_n courage_n etc._n etc._n for_o it_o be_v impossible_a to_o be_v gay_a and_o good_a humour_a serene_a cheerful_a courageous_a and_o magnanimous_a and_o at_o the_o same_o time_n sorrowful_a fearful_a peevish_a fretful_a etc._n etc._n if_o the_o bare_a sense_n of_o a_o ordinary_a meal_n of_o meat_n at_o stomach_n which_o cause_v but_o a_o slow_a pleasure_n in_o comparison_n with_o opium_n take_v off_o the_o peevishness_n fretfulness_n etc._n etc._n that_o the_o grievous_a sensation_n of_o hunger_n cause_n how_o much_o more_o must_v the_o intense_a and_o charm_a pleasure_n cause_v by_o opium_n that_o be_v so_o agreeable_a even_o far_o beyond_o wine_n itself_o as_o have_v be_v set_v forth_o take_v away_o all_o ill_a humour_n fretfulness_n peevishness_n etc._n etc._n obj._n but_o it_o may_v be_v say_v that_o sleepiness_n which_o depend_v also_o upon_o relaxation_n as_o the_o effect_n of_o pleasure_n do_v cause_v a_o peevish_a fretful_a humour_n as_o be_v common_o observe_v ans._n it_o be_v so_o far_o otherwise_o in_o the_o case_n of_o opium_n that_o it_o be_v quite_o contrary_a for_o 1._o the_o sleepy_a be_v not_o peevish_a unless_o you_o put_v they_o by_o some_o mean_v out_o of_o the_o pleasure_n of_o enjoy_v sleep_n or_o relaxation_n for_o if_o you_o let_v they_o alone_o they_o will_v not_o trouble_v you_o with_o peevishness_n nor_o any_o ill_a humour_n but_o it_o be_v the_o call_v they_o from_o their_o relaxed_a condition_n to_o the_o grievous_a task_n of_o contraction_n that_o vex_v they_o so_o that_o it_o be_v the_o want_n of_o continue_v under_o the_o relaxation_n that_o fret_v they_o and_o the_o more_o because_o the_o fatigue_n and_o tedium_n of_o contraction_n do_v put_v they_o upon_o the_o relief_n of_o sleep_n of_o which_o if_o disappoint_v they_o be_v much_o vex_v but_o in_o the_o case_n of_o opium_n you_o can_v so_o easy_o rob_v they_o of_o their_o pleasure_n which_o they_o carry_v continual_o within_o they_o in_o a_o uninterrupted_a manner_n unless_o some_o very_a grievous_a thing_n happen_v which_o cause_v more_o defensive_a contraction_n than_o the_o opium_n cause_v relaxation_n though_o even_o this_o also_o be_v general_o soon_o overcome_v by_o the_o pleasure_n continual_o invite_v the_o relaxation_n and_o promote_a it_o whereas_o the_o interruption_n thereof_o be_v transitory_a but_o at_o the_o worst_a it_o be_v but_o take_v more_o opium_n and_o the_o work_n be_v do_v for_o i_o observe_v that_o the_o do_v of_o opium_n must_v be_v sufficient_a to_o introduce_v such_o a_o sense_n of_o pleasure_n as_o cause_v a_o relaxation_n of_o the_o contraction_n cause_v by_o the_o grievance_n hence_o it_o be_v certain_a that_o a_o great_a pain_n require_v a_o large_a do_v of_o opium_n as_o have_v be_v intimate_v 6._o all_o know_v that_o pleasant_a diversion_n as_o music_n pleasant_a jest_n and_o story_n fine_a sight_n etc._n etc._n do_v cause_n euphory_n and_o a_o easy_a undergo_n of_o journey_n labour_n etc._n etc._n therefore_o if_o such_o interrupt_v transient_a and_o slight_a pleasure_n do_v it_o so_o much_o it_o will_v be_v easy_o grant_v i_o that_o a_o continual_a and_o more_o intense_a pleasure_n that_o be_v always_o present_a without_o any_o interruption_n or_o intermission_n as_o that_o of_o opium_n must_v cause_v a_o more_o eminent_a and_o permanent_a euphory_n proportion_v to_o the_o pleasure_n which_o cause_v relaxation_n prevent_v the_o fatigue_n or_o lassitude_n that_o be_v cause_v only_o by_o contraction_n either_o vigilative_a defensive_a or_o intentive_a as_o i_o have_v prove_v so_o that_o i_o do_v not_o conceive_v how_o the_o noctambuli_n or_o such_o as_o walk_v in_o their_o sleep_n can_v ever_o be_v tire_v if_o they_o travel_v ever_o so_o far_o if_o they_o can_v eat_v and_o drink_v because_o the_o relaxation_n of_o the_o sleep_v recruit_n they_o as_o much_o as_o they_o spend_v of_o spirit_n etc._n etc._n so_o person_n that_o cause_v such_o relaxation_n by_o opium_n and_o so_o repeat_v it_o as_o to_o maintain_v the_o relaxation_n can_v hardly_o be_v weary_a which_o be_v the_o true_a plain_a and_o mechanical_a reason_n why_o the_o turk_n and_o other_o eastern_a people_n do_v by_o the_o help_n of_o opium_n perform_v prodigious_a journey_n without_o be_v tire_v which_o may_v therefore_o in_o allusion_n to_o the_o noctambuli_n be_v call_v opiambuli_n or_o opambuli_n as_o be_v a_o kind_n of_o artificial_a noctambuli_n because_o they_o be_v much_o relax_v by_o the_o pleasure_n that_o opium_n cause_n as_o the_o other_o be_v by_o sleep_n qui_fw-la laetitiâ_fw-la aâ—iciuntur_fw-la say_v sanctorius_n nuâ—lam_n in_o itinere_fw-la defatigationem_fw-la sentiunt_fw-la that_o be_v the_o merry_a be_v not_o weary_a as_o the_o say_v be_v because_o mirth_n be_v pleasant_a cause_v relaxation_n as_o opium_n do_v in_o some_o measure_n note_v that_o as_o to_o all_o the_o forego_n serene_a and_o brisk_a effect_n a_o full_a and_o liberal_a perspiration_n which_o it_o also_o cause_n as_o will_v be_v show_v contribute_v much_o thereto_o a_o posteriori_fw-la for_o as_o fire_n burn_v slow_o and_o dull_o if_o the_o smoke_n do_v by_o any_o mean_n return_v upon_o it_o and_o very_o serene_a if_o not_o so_o it_o be_v with_o the_o flame_n of_o life_n if_o cloud_v with_o or_o clear_v from_o vapour_n by_o perspiration_n sanctor_n sect._n 7._o aph._n 17._o mâ—lancholia_fw-la superatur_fw-la liberâ_fw-la perspiratione_fw-la &_o aph._n 30._o 31._o edulia_n aperientia_fw-la gaudium_fw-la movent_fw-la that_o be_v such_o as_o open_v the_o pore_n and_o cause_n perspiration_n cause_n joy_n or_o mirth_n 7._o it_o lull_v soothe_v and_o as_o it_o be_v charm_v the_o mind_n with_o consent_n and_o acquiescence_n for_o the_o several_a reason_n couch_v in_o the_o premise_n and_o because_o the_o fine_a continual_a and_o charm_a pleasure_n of_o opium_n such_o as_o some_o glass_n of_o generous_a wine_n cause_v must_v needs_o have_v such_o a_o effect_n 8._o it_o quiet_v allay_v and_o compose_v all_o perturbation_n and_o commotion_n of_o the_o sensitive_a soul_n spirit_n etc._n etc._n 1._o because_o it_o so_o lull_v soothe_v and_o charm_n the_o sensitive_a soul_n as_o be_v aforesaid_a who_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n 2._o because_o all_o motion_n be_v by_o the_o relaxation_n proportionable_o abate_v as_o be_v demonstrate_v thus_o opium_n take_v off_o hysterick_n fit_v fever_n from_o commotion_n of_o the_o spirit_n convulsion_n stop_v hemerrhage_n or_o bleed_v &c._n &c._n 9_o it_o cause_v a_o relaxation_n of_o all_o the_o sensile_a part_n of_o the_o body_n by_o reason_n of_o the_o great_a and_o continual_a pleasure_n that_o it_o cause_n and_o how_o pleasure_n cause_v relaxation_n i_o have_v show_v in_o chap._n 14._o 10._o it_o cause_v indolence_n or_o exemption_n from_o pain_n by_o cause_v so_o high_a and_o last_a a_o pleasure_n 1._o because_o that_o pleasure_n take_v up_o the_o attention_n of_o the_o sensitive_a soul_n who_o delight_v in_o it_o 2._o because_o a_o sense_n of_o pleasure_n and_o pain_n can_v be_v at_o the_o same_o time_n in_o the_o same_o subject_a be_v they_o be_v contrary_n 3._o because_o the_o membrane_n be_v relax_v and_o the_o animal_n spirit_n expanded_a the_o impression_n of_o pain_n can_v be_v carry_v to_o the_o sensitive_a soul_n because_o they_o can_v convey_v impression_n smart_o be_v thus_o relax_v and_o expanded_a as_o have_v be_v demonstrate_v by_o the_o comparison_n of_o a_o gut_n half_n full_a of_o air_n etc._n etc._n and_o all_o impression_n of_o pain_n must_v be_v smart_n or_o else_o they_o be_v not_o impression_n of_o pain_n for_o gentle_a impression_n be_v such_o as_o belong_v to_o oil_n smooth_a and_o soft_a thing_n or_o when_o the_o animal_n spirit_n can_v hardly_o carry_v any_o impression_n but_o gentle_o as_o in_o sleep_n and_o other_o relaxation_n as_o that_o upon_o pleasure_n etc._n etc._n which_o be_v our_o case_n note_v that_o it_o will_v cause_v indolence_n without_o cause_v sleep_n because_o sleep_n require_v relaxation_n and_o quiet_a of_o the_o spirit_n but_o indolence_n require_v only_a relaxation_n as_o be_v show_v which_o always_o follow_v the_o charm_a pleasure_n of_o opium_n 11._o it_o stop_v moderate_v or_o palliate_n most_o flux_n and_o promote_v perspiration_n because_o the_o relaxation_n take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o cause_v a_o contraction_n to_o squeeze_v they_o out_o and_o that_o the_o same_o relaxation_n open_v the_o pore_n to_o let_v the_o foam_n out_o which_o pass_v by_o their_o own_o levity_n upon_o the_o open_n of_o the_o pore_n nihil_fw-la magis_fw-la say_v sanctorius_n
part_n by_o its_o relax_v the_o pore_n of_o the_o kidney_n and_o render_v the_o humour_n more_o penetrate_v in_o some_o measure_n by_o the_o volatile_a salt_n 20._o it_o cause_v a_o nausea_n by_o its_o rosin_n stick_v to_o and_o teaze_v the_o sensile_a coat_n of_o the_o stomach_n the_o reason_n why_o it_o be_v general_o so_o long_o before_o it_o cause_v a_o nausea_n or_o vomit_v be_v that_o its_o pleasure_n do_v at_o first_o prevent_v it_o till_o at_o last_o the_o stick_a rosin_n urge_v it_o by_o its_o long_a stay_n and_o vexatious_a adherence_n 21._o it_o cause_v swimmings_n in_o the_o head_n by_o consent_n when_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o you_o find_v upon_o nauseas_fw-la before_o vomit_v or_o when_o any_o thing_n do_v much_o offend_v the_o stomach_n as_o much_o drink_n or_o wine_n which_o when_o they_o have_v vomit_v those_o swimming_n cease_v 22._o it_o cause_v watch_v in_o some_o person_n who_o be_v of_o very_o movable_a spirit_n by_o actuate_a and_o stir_v their_o spirit_n by_o its_o active_a volatile_a salt_n though_o it_o do_v at_o the_o same_o time_n please_v the_o membrane_n and_o consequent_o relax_v the_o sensile_a part_n and_o thereby_o cause_n indolence_n the_o effect_n of_o relaxation_n which_o it_o also_o do_v when_o people_n keep_v themselves_o from_o sleep_n by_o voluntary_a motion_n and_o therefore_o take_v away_o pain_n even_o when_o man_n travel_v etc._n etc._n beside_o there_o be_v some_o sort_n of_o person_n that_o upon_o joy_n good_a news_n pleasure_n or_o the_o like_a be_v too_o much_o elevate_v or_o have_v a_o restless_a ovation_n of_o the_o spirit_n which_o will_v not_o suffer_v they_o to_o sleep_n though_o they_o be_v in_o a_o pleasant_a condition_n all_o the_o time_n this_o may_v be_v the_o case_n of_o some_o that_o can_v sleep_v after_o opium_n though_o they_o be_v all_o the_o time_n as_o they_o call_v it_o in_o a_o heavenly_a condition_n for_o as_o i_o have_v say_v a_o quietness_n of_o the_o spirit_n be_v requisite_a to_o cause_v sleep_n as_o well_o as_o relaxation_n but_o relaxation_n alone_o and_o thereby_o expansion_n of_o the_o spirit_n so_o that_o they_o can_v carry_v impression_n smart_o be_v sufficient_a to_o cause_v indolence_n and_o the_o pleasure_n to_o cause_v a_o heavenly_a or_o very_o pleasant_a condition_n sanctor_n stat._n med._n sect._n 7._o aph._n 28._o say_v that_o laetitia_n perseverans_fw-la per_fw-la multos_fw-la dies_fw-la somnum_fw-la impedit_fw-la persevere_v pleasure_n may_v do_v the_o same_o by_o like_a reason_n that_o be_v too_o much_o 〈◊〉_d or_o ovation_n of_o the_o spirit_n sometime_o too_o large_a a_o do_v cause_n watch_v by_o over-actuating_a and_o exciting_a the_o spirit_n medicum_fw-la vini_fw-la generosi_fw-la &_o allium_fw-la say_v sanctorius_n conciliant_fw-la somnum_fw-la &_o perspirationem_fw-la si_fw-la vero_fw-la plus_fw-la justo_fw-la sumantur_fw-la utrumque_fw-la prohibent_fw-la perspirabile_fw-la tamen_fw-la in_o sudorem_fw-la convertunt_fw-la that_o be_v a_o little_a generous_a wine_n and_o garlic_n will_v cause_v sleep_n and_o perspiration_n but_o too_o much_o hinder_v both_o yet_o they_o convert_v the_o perspirable_a matter_n to_o a_o sweat_n which_o wine_n and_o garlick_n have_v the_o nature_n of_o opiate_n and_o the_o reason_n why_o they_o sweat_v be_v the_o quantity_n of_o the_o wine_n afford_v more_o moisture_n hypocrates_n say_v 23._o a_o dubious_a state_n between_o sleep_v and_o wake_v be_v cause_v when_o the_o relaxation_n upon_o the_o pleasure_n of_o opium_n incline_v to_o sleep_v but_o the_o irreâ—uiete_a ovation_n of_o the_o spirit_n by_o the_o pleasure_n and_o titillation_n will_v hardly_o suffer_v it_o yet_o high_o please_v and_o put_v they_o in_o a_o sweet_a agreeable_a condition_n chap._n xix_o the_o explication_n of_o the_o rare_a effect_n of_o opium_n in_o a_o moderate_a do_v 1._o it_o cause_v temporary_a pulse_n of_o the_o 〈◊〉_d and_o sometime_o of_o other_o part_n by_o its_o over_o relax_v the_o part_n and_o cause_v thereby_o a_o expansion_n of_o the_o elastic_a spirit_n which_o as_o be_v demonstrate_v weaken_v their_o motion_n 2._o falter_v of_o the_o tongue_n do_v as_o in_o relaxation_n by_o drunkenness_n proceed_v from_o the_o same_o cause_n 3._o looseness_n of_o the_o low_a jaw_n as_o you_o see_v in_o the_o drowsy_a and_o drunken_a people_n be_v from_o the_o same_o relaxation_n 4._o it_o sometime_o prevent_v sweat_n by_o cause_v a_o very_a liberal_a perspiration_n as_o be_v show_v for_o as_o sanctorius_n say_v who_o shall_v know_v it_o much_o insensible_a perspiration_n and_o sweat_n can_v consist_v especial_o in_o a_o temperate_a person_n who_o eat_v and_o drink_v moderate_o therefore_o if_o you_o keep_v a_o person_n that_o sweat_v much_o at_o night_n in_o a_o free_a perspiration_n all_o day_n by_o the_o help_n of_o a_o opiate_n you_o will_v much_o lessen_v or_o total_o prevent_v the_o sweat_n at_o night_n as_o in_o consumptive_a person_n etc._n etc._n 5._o it_o cause_v abortion_n by_o relax_v the_o neck_n of_o the_o womb_n which_o also_o the_o pleasure_n of_o coition_n sometime_o do_v for_o the_o like_a reason_n and_o will_v be_v much_o more_o apt_a to_o cause_v it_o if_o it_o continue_v long_o as_o that_o of_o opium_n do_v note_v the_o inconvenience_n of_o coition_n after_o impregnation_n this_o be_v the_o great_a cause_n that_o whore_n be_v not_o apt_a to_o bear_v child_n because_o frequency_n of_o pleasure_n do_v over-relax_a the_o collum_n 〈◊〉_d 6._o it_o prevent_v abortion_n when_o fear_n terror_n or_o any_o contract_a cause_n as_o grief_n grievous_a passion_n or_o sensation_n do_v threaten_v it_o by_o its_o take_n off_o the_o contraction_n and_o grievance_n that_o cause_v it_o 7_o intumescence_n of_o the_o lip_n be_v from_o their_o relaxation_n admit_v the_o blood_n and_o humour_n into_o they_o in_o a_o plentiful_a manner_n beside_o that_o their_o laxity_n and_o the_o inadvertency_n occasion_v by_o the_o divert_v pleasure_n or_o drowsiness_n that_o follow_v let_v the_o low_a lip_n hang_v down_o careless_o as_o be_v usual_a in_o such_o case_n may_v by_o expose_v much_o more_o of_o that_o lip_n which_o be_v most_o concern_v in_o this_o effect_n make_v it_o seem_v large_a as_o a_o hang_a lip_n do_v 8._o it_o may_v cure_v a_o dropsy_n as_o dr._n wâ—llis_n do_v instance_n 1._o by_o cause_v a_o free_a perspiration_n which_o be_v much_o want_v in_o those_o case_n 2._o by_o relax_v the_o pore_n and_o make_v way_n for_o the_o humour_n to_o 〈◊〉_d 3._o by_o cause_v much_o urine_n as_o cantharides_n millepedes_n &c_n &c_n do_v upon_o the_o account_n of_o their_o volatile-salt_n with_o which_o opium_n abound_v 9_o it_o cure_v stupor_n that_o proceed_v from_o contraction_n as_o by_o cold_a etc._n etc._n by_o relax_v all_o part_n 10._o it_o cause_v anxiety_n and_o distress_n by_o the_o rosin_n stick_v and_o teaze_v the_o stomach_n 11._o vomit_n and_o hiccough_n proceed_v from_o the_o same_o cause_n 12._o convulsion_n be_v cause_v by_o the_o same_o rosin_n while_o it_o continual_o urge_v the_o stomach_n to_o grievous_a vomit_n which_o at_o last_o draw_v other_o part_n as_o the_o stomach_n usual_o do_v when_o under_o great_a grievance_n into_o violent_a contraction_n or_o convulsion_n by_o consent_n to_o endeavour_v its_o assistance_n because_o the_o defensive_a contraction_n grow_v very_o high_a by_o the_o almost_o intolerable_a and_o tedious_a grievance_n at_o stomach_n cause_v a_o mighty_a compression_n of_o the_o springy_a animal_n spirit_n by_o which_o mean_v they_o grow_v very_o forcible_a irrequiete_a and_o violent_o springy_a under_o the_o urgency_n of_o a_o enormous_a compressure_n which_o cause_v such_o convulsive_a motion_n note_v that_o such_o a_o violent_a compression_n of_o the_o animal_n spirit_n into_o a_o great_a springiness_n be_v the_o cause_n of_o the_o strength_n of_o convulsive_a motion_n so_o that_o sometime_o a_o strong_a man_n can_v hardly_o hold_v a_o child_n limb_n in_o such_o case_n 13._o syncopes_fw-la leipothymy_n and_o faint_n follow_v when_o the_o sensitive_a soul_n be_v quite_o tire_v and_o overbear_v by_o the_o fatigue_n of_o such_o distress_n vomit_n and_o defensive_a contraction_n to_o reject_v and_o excuss_v the_o say_v adhere_v and_o teaze_v rosin_n yield_v itself_o to_o rest_n and_o let_v we_o go_v the_o reign_v of_o contraction_n as_o be_v fruitless_a and_o no_o long_o endurable_a whereupon_o all_o the_o sensile_a part_n be_v relax_v in_o the_o high_a degree_n they_o thereby_o grow_v unfit_a for_o sensation_n and_o the_o animal_n spirit_n expand_v as_o far_o as_o the_o atmospherical_a compressure_n permit_v they_o so_o that_o they_o grow_v incapable_a to_o convey_v impression_n by_o which_o mean_v sense_n fail_v and_o motion_n also_o for_o the_o same_o reason_n because_o the_o animal_n spirit_n loose_v their_o springy_a endeavour_n for_o want_n of_o a_o sufficient_a compression_n to_o render_v they_o flippant_a for_o the_o purpose_n which_o be_v the_o cause_n as_o in_o sleep_n that_o sense_n
contract_v it_o be_v round_o even_o polite_a and_o true_o represent_v thing_n 11._o deadness_n of_o the_o eye_n to_o the_o view_n be_v as_o have_v be_v show_v from_o the_o laxity_n of_o the_o cornea_n which_o make_v it_o flag_n lie_v loose_a look_v dull_o and_o not_o due_o reflect_v a_o smart_n and_o brisk_a speck_n of_o light_n as_o it_o do_v when_o tense_n round_o and_o polite_a by_o its_o contraction_n on_o the_o contain_v humour_n which_o then_o due_o fill_v it_o 12._o falter_v of_o the_o tongue_n be_v from_o the_o same_o relaxation_n as_o in_o drunken_a person_n 13._o a_o sopor_fw-la be_v from_o the_o same_o relaxation_n over_o all_o the_o sensile_a part_n of_o the_o body_n by_o which_o mean_v sense_n and_o motion_n be_v diminish_v or_o lose_v by_o the_o expansion_n of_o the_o animal_n spirit_n which_o as_o have_v be_v say_v be_v not_o due_o compress_v become_v unfit_a for_o both_o at_o the_o same_o time_n 14._o a_o slow_a and_o wide_a pulse_n be_v from_o the_o same_o cause_n because_o the_o say_a relaxation_n permit_v the_o artery_n to_o widen_v and_o the_o animal_n spirit_n to_o expand_v and_o consequent_o render_v the_o motion_n of_o the_o heart_n slow_a which_o be_v the_o cause_n of_o the_o pulse_n 15._o a_o high_a colour_n or_o efflorescence_n of_o the_o skin_n have_v be_v explain_v 16._o looseness_n of_o the_o jaw_n and_o lip_n be_v from_o the_o same_o relaxation_n as_o be_v show_v and_o so_o be_v 17._o intumescence_n of_o the_o lip_n as_o have_v be_v show_v 18._o difficulty_n of_o breathe_v may_v be_v from_o two_o different_a cause_n either_o by_o the_o relaxation_n weaken_v the_o requisite_a motion_n for_o want_n of_o compressure_n of_o the_o animal_n spirit_n and_o by_o the_o flaccity_n of_o the_o part_n themselves_o or_o by_o a_o great_a grievance_n at_o stomach_n upon_o the_o account_n of_o the_o rosin_n stick_v to_o it_o and_o cause_v a_o convulsion_n of_o those_o part_n both_o which_o may_v happen_v 19_o fury_n and_o madness_n may_v also_o happen_v either_o by_o the_o exalt_a pleasure_n of_o its_o titillation_n as_o in_o drunkard_n who_o therefore_o scarce_o know_v what_o they_o do_v the_o mind_n be_v as_o be_v say_v alienate_v or_o it_o may_v happen_v as_o i_o have_v often_o know_v a_o kind_n of_o madness_n to_o be_v produce_v by_o a_o great_a grievance_n at_o stomach_n which_o may_v well_o be_v from_o the_o rosin_n grieve_v and_o teaze_v the_o nice_o sensile_a stomach_n they_o may_v be_v easy_o distinguish_v one_o viz._n that_o from_o the_o rosin_n at_o stomach_n be_v with_o great_a distress_n anxiety_n convulsion_n etc._n etc._n and_o the_o other_o without_o any_o 20._o venereal_a fury_n proceed_v from_o the_o high_a titillation_n of_o the_o venereal_a membrane_n by_o the_o volatile_a salt_n of_o so_o much_o opium_n as_o if_o cantharides_n bee_n &c_n &c_n be_v take_v internal_o but_o that_o these_o can_v so_o agreeable_o titillate_v those_o part_n as_o opium_n do_v who_o volatile_a particle_n be_v render_v more_o please_a by_o oily_a one_o and_o therefore_o much_o of_o the_o nature_n of_o semen_n virile_a 21._o priapism_n be_v cause_v by_o the_o same_o continual_a titillation_n 22._o violent_a itch_n of_o the_o skin_n be_v cause_v by_o the_o same_o tickle_a volatile_a particle_n in_o great_a abundance_n proportionable_a to_o the_o excessive_a do_v 23._o nauseas_fw-la be_v cause_v by_o the_o rosin_n stick_v at_o and_o solicit_v the_o stomach_n to_o vomit_v 24._o swimmings_n in_o the_o head_n be_v by_o conseâ—it_n because_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o be_v observe_v in_o many_o case_n from_o a_o grieve_a stomach_n upon_o a_o tendency_n to_o vomit_v as_o when_o it_o be_v overload_v with_o wine_n or_o indigestible_a victual_n or_o when_o person_n be_v sea_n or_o coach-sick_a etc._n etc._n for_o it_o be_v not_o in_o these_o last_o case_n because_o the_o brain_n be_v offend_v as_o people_n imagine_v that_o they_o be_v sick_a or_o vomit_n but_o the_o swim_v in_o the_o head_n and_o offence_n of_o the_o brain_n happen_v because_o the_o stomach_n be_v offend_v by_o the_o motion_n of_o the_o coach_n or_o ship_n by_o reason_n of_o its_o most_o exquisite_a sensation_n which_o the_o effluvias_fw-la of_o a_o cat_n pestiferous_a particle_n and_o commotion_n cause_v by_o mear_v passion_n can_v and_o do_v offend_v as_o be_v say_v so_o as_o to_o cause_v vomit_n anxiety_n etc._n etc._n much_o more_o than_o may_v the_o motion_n of_o a_o ship_n or_o coach_n do_v it_o i_o shall_v not_o here_o enter_v into_o controversy_n with_o those_o that_o assert_v that_o it_o be_v the_o head_n be_v first_o offend_v in_o a_o coach_n or_o ship_n it_o be_v sufficient_a for_o my_o purpose_n that_o grievance_n at_o stomach_n do_v common_o cause_n swimmings_n in_o the_o head_n for_o take_v off_o those_o grievance_n cure_v they_o as_o eat_v when_o it_o be_v from_o the_o grievance_n of_o hunger_n or_o wind_n at_o stomach_n and_o discharge_v the_o stomach_n of_o a_o great_a load_n of_o wine_n ale_z or_o indigestible_a matter_n when_o such_o thing_n cause_v it_o do_v cure_v such_o swimming_n in_o the_o head_n the_o way_n how_o grievance_n at_o stomach_n do_v cause_n those_o swimming_n be_v by_o cause_v a_o contraction_n as_o all_o grievance_n do_v but_o especial_o those_o at_o stomach_n of_o the_o membrane_n of_o the_o brain_n as_o it_o do_v of_o all_o other_o but_o main_o of_o these_o because_o very_o sensile_a by_o which_o mean_v the_o animal_n spirit_n be_v compress_v grow_v more_o irrequiete_a and_o skip_a up_o and_o down_o and_o the_o compression_n not_o be_v continual_o alike_o in_o general_n or_o the_o artery_n afford_v a_o uneven_a and_o forcible_a supply_n of_o they_o or_o fume_n from_o the_o blood_n by_o the_o compression_n nor_o affect_v all_o part_n of_o the_o brain_n with_o equal_a force_n because_o the_o pleasure_n endeavour_n to_o relax_v etc._n etc._n there_o must_v thence_o arise_v eddy_n vortices_fw-la or_o whirl_v thereof_o which_o cause_n swimmings_n vertigo_n &c._n &c._n according_a as_o they_o happen_v to_o be_v move_v that_o they_o happen_v from_o such_o contraction_n be_v manifest_a 1._o because_o the_o grievance_n at_o stomach_n can_v add_v nothing_o else_o to_o the_o brain_n or_o its_o membrane_n 2._o because_o they_o be_v take_v off_o by_o please_v the_o stomach_n and_o consequent_o by_o relaxation_n as_o by_o a_o glass_n of_o wine_n victual_n a_o opiate_n that_o be_v not_o resinous_a etc._n etc._n it_o be_v here_o well_o worth_a your_o notice_n that_o all_o consent_n of_o part_n a_o thing_n much_o admire_v be_v only_o by_o contraction_n or_o relaxation_n which_o sudden_o affect_v the_o whole_a systeme_n of_o the_o nerve_n and_o membrane_n 25._o vertigo_n be_v from_o the_o same_o cause_n 26._o vomit_n be_v cause_v as_o be_v say_v by_o the_o great_a grievance_n of_o the_o acrimonious_a rosin_n stick_v to_o the_o coat_n of_o the_o stomach_n 27._o hiccongh_n be_v from_o the_o same_o cause_n which_o happen_v upon_o the_o decay_n of_o power_n vigorous_o to_o vomit_v dwindle_v into_o those_o fruitless_a convulsive_a subsultory_n jerâ—_n or_o half_a endeavour_n 28._o distress_n and_o anxiety_n must_v necessary_o attend_v such_o a_o grievous_a sensation_n and_o desection_n of_o nature_n endeavour_v as_o be_v overbear_v and_o disable_v to_o work_v for_o itself_o 29._o a_o turbulent_a pulse_n must_v be_v a_o effect_n of_o the_o forego_n tumult_n 30._o convulsion_n happen_v as_o be_v show_v by_o the_o enormous_a compression_n of_o the_o animal_n spirit_n by_o reason_n of_o the_o violent_a contraction_n upon_o the_o great_a grievance_n by_o the_o rosin_n at_o stomach_n which_o cause_v they_o to_o skip_v and_o fling_v up_o and_o down_o very_o forcible_o under_o the_o squeeze_v of_o the_o compression_n and_o possible_o skirmish_v under_o the_o vicissitude_n of_o it_o and_o relaxation_n 31._o faint_n and_o leipothymy_n be_v cause_v as_o have_v be_v explain_v by_o the_o sensitive_a soul_n be_v overtired_n by_o the_o fatigue_n of_o defensive_a contraction_n and_o yield_v himself_o to_o rest_n from_o all_o contraction_n as_o the_o last_o relief_n etc._n etc._n whereupon_o sense_n and_o motion_n do_v fail_v for_o want_v of_o compression_n to_o render_v the_o spirit_n springy_a active_a and_o fit_a for_o the_o purpose_n 32._o cold_a breath_n be_v but_o a_o necessary_a consequence_n of_o the_o loss_n of_o motion_n and_o therefore_o of_o heat_n by_o such_o leipothymy_n and_o faint_n 33._o death_n be_v cause_v two_o manner_n of_o way_n that_o be_v either_o by_o a_o utter_a expense_n of_o spirit_n and_o thereupon_o a_o dereliction_n or_o extinction_n of_o the_o sensitive_a soul_n by_o reason_n of_o those_o distress_n and_o fatigue_n upon_o the_o account_n of_o the_o invincible_a rosin_n or_o by_o too_o much_o relaxation_n disable_n all_o the_o motion_n of_o the_o body_n as_o in_o such_o as_o die_v be_v dead_a drink_v
noxious_a rosin_n and_o all_o filth_n and_o dross_n of_o the_o opium_n 2._o it_o must_v be_v keep_v entire_a without_o weaken_v or_o any_o way_n alter_v it_o or_o add_v a_o new_a quality_n thereto_o therefore_o 1._o opium_n must_v not_o be_v torrefy_v according_a to_o the_o common_a practice_n 1._o because_o the_o fine_a and_o most_o volatile_a part_n which_o be_v the_o very_o best_a be_v thereby_o lose_v 2._o because_o the_o resinous_a and_o earthy_a part_n which_o be_v not_o spend_v that_o way_n grow_v more_o in_o proportion_n to_o the_o sal-volatile-oleosum_a so_o that_o torrefy_v can_v be_v allow_v unless_o preserve_v the_o bad_a and_o destroy_v the_o good_a be_v allowable_a the_o vain_a and_o ostentatious_a pretence_n of_o destroy_v i_o know_v not_o what_o narcotick_a sulphur_n which_o be_v a_o nickname_n give_v by_o ignorance_n to_o the_o best_a part_n of_o opium_n be_v most_o insufferable_a stuff_n 3._o because_o all_o empyreùm_fw-la which_o render_v it_o very_o nauseous_a can_v hardly_o be_v avoid_v in_o torresy_v it_o but_o suppose_v it_o be_v what_o need_n be_v there_o otherwise_o so_o to_o damnify_v it_o as_o be_v aforesaid_a obj._n it_o be_v find_v to_o be_v more_o innocent_a after_o such_o torrefaction_n ans._n i_o grant_v that_o it_o happen_v so_o sometime_o but_o it_o must_v be_v mere_o by_o accident_n either_o 1._o because_o it_o meet_v with_o a_o strong_a digestion_n at_o stomach_n or_o 2._o by_o the_o custom_n of_o powder_a it_o which_o be_v always_o direct_v and_o do_v after_o the_o torrefaction_n by_o which_o mean_v the_o resinous_a part_n be_v divide_v and_o sever_v become_v less_o liable_a to_o a_o coalescence_n at_o stomach_n and_o consequent_o less_o offensive_a and_o more_o subduable_a especial_o 3._o when_o it_o be_v mix_v as_o general_o it_o be_v with_o other_o thing_n that_o keep_v the_o part_n of_o the_o rosin_n from_o coalescence_n and_o leave_v they_o more_o conquerable_a by_o the_o digestion_n as_o the_o ancient_n find_v by_o experience_n who_o therefore_o do_v general_o if_o not_o always_o mix_v it_o in_o a_o small_a quantity_n with_o many_o other_o thing_n in_o great_a quantity_n in_o the_o form_n of_o electuary_n as_o in_o venice-treacle_n mithridate_n etc._n etc._n though_o nothing_o in_o they_o correct_v the_o opium_n otherwise_o than_o by_o divide_v and_o segregate_a its_o part_n this_o indeed_o be_v like_o that_o of_o divide_v &_o impera_fw-la or_o interline_v suspect_v soldier_n with_o trusty_a or_o friendly_a one_o to_o prevent_v a_o mischievous_a conspiracy_n but_o how_o much_o better_o be_v it_o to_o have_v no_o enemy_n to_o contest_v with_o by_o a_o due_a and_o complete_a separation_n of_o the_o rosin_n from_o the_o opium_n otherwise_o you_o must_v be_v oblige_v to_o good_a accident_n if_o ever_o torrefy_v opium_n become_v safe_a because_o all_o the_o noxious_a rosin_n be_v leave_v in_o it_o therefore_o if_o after_o torrefaction_n you_o will_v give_v it_o in_o a_o mass_n without_o powder_a it_o and_o mix_v it_o with_o other_o thing_n you_o will_v find_v its_o ill_a effect_n to_o be_v as_o bad_a if_o not_o worse_o than_o ever_o as_o you_o will_v also_o if_o you_o afterward_o extract_v it_o out_o of_o spirit_n of_o wine_n reduce_v it_o into_o the_o form_n of_o pill_n by_o which_o mean_v the_o sever_a part_n of_o the_o powdered_a rosin_n do_v again_o coalesce_v into_o a_o lumpish_a condition_n which_o render_v it_o worse_o than_o crude_a opium_n as_o wedelius_n myself_o and_o other_o do_v testify_v because_o the_o opium_n be_v somewhat_o weaken_v and_o all_o the_o rosin_n remain_v the_o do_v of_o the_o opium_n and_o consequent_o of_o its_o rosin_n must_v be_v increase_v as_o suppose_v 8_o grain_n of_o crude_a opium_n have_v 2_o of_o rosin_n 2_o of_o other_o dross_n 2_o of_o phlegm_n and_o 2_o of_o sal-volatile-oleosum_a and_o that_o 2_o grain_n of_o the_o crude_a opium_n contain_v half_o a_o grain_n of_o the_o sal-volotile-oleosum_a be_v the_o dose_n then_o if_o in_o torrefy_v it_o one_o grain_n of_o the_o sal-volatile-oleosum_a be_v lose_v and_o another_o of_o the_o phlegm_n there_o will_v remain_v only_o 6_o grain_n of_o the_o opium_n with_o the_o virtue_n of_o one_o grain_n of_o the_o sal-volatile-oleosum_a in_o it_o therefore_o 3_o grain_n of_o it_o must_v be_v now_o use_v to_o have_v half_o a_o grain_n of_o the_o sal-volatile-oleosum_a which_o 3_o grain_n will_v contain_v half_o the_o rosin_n of_o the_o whole_a mass_n that_o be_v one_o grain_n whereas_o there_o be_v but_o half_a a_o grain_n thereof_o in_o the_o 2_o grain_n of_o crude_a opium_n therefore_o torrefy_v opium_n be_v in_o itself_o much_o worse_a than_o crude_a opium_n and_o it_o be_v yet_o worse_o if_o after_o torrefication_n you_o make_v a_o extract_n of_o it_o in_o spirit_n of_o wine_n for_o then_o the_o dross_n and_o phlegm_n be_v separate_v from_o the_o 6_o grain_n nothing_o will_v remain_v in_o the_o extract_v but_o the_o resinous_a part_n with_o less_o of_o the_o virtue_n of_o the_o sal-volatile-oleosum_a which_o be_v not_o take_v up_o so_o greedy_o as_o the_o rosin_n be_v by_o the_o spirit_n of_o wine_n beside_o that_o some_o of_o this_o volatile_a part_n may_v be_v lose_v and_o that_o the_o rosin_n be_v now_o more_o compact_v as_o not_o have_v as_o much_o as_o the_o drossy_a earthy_a or_o watery_a part_n to_o sever_v and_o keep_v its_o noxious_a particle_n at_o a_o distance_n to_o render_v they_o as_o be_v show_v more_o subduable_a and_o digestible_a at_o stomach_n see_v what_o pain_n the_o inconsiderate_a world_n do_v take_v and_o exceed_o host_n of_o to_o render_v opium_n by_o torrefaction_n extraction_n in_o spirit_n of_o wine_n etc._n etc._n at_o least_o twice_o as_o nozious_a as_o crude_a opium_n without_o account_v how_o far_o the_o sal-volatile-oleosum_a that_o remain_v be_v impair_v by_o the_o fire_n and_o spirit_n of_o wine_n it_o be_v therefore_o no_o wonder_n that_o wedelius_n declare_v that_o he_o find_v more_o mischief_n by_o such_o extract_v out_o of_o spirit_n of_o wine_n than_o any_o other_o preparation_n of_o opium_n it_o be_v plain_a then_o ii_o that_o we_o must_v not_o extract_v it_o out_o of_o spirit_n of_o wine_n or_o any_o such_o sulphureous_a menstruum_fw-la 1._o because_o more_o apt_a to_o extract_v the_o rosin_n than_o the_o sal-volatile-oleosum_a 2._o because_o the_o rosin_n will_v be_v more_o compact_v 3._o because_o the_o spirit_n of_o wine_n may_v in_o some_o measure_n alter_v it_o iii_o we_o must_v not_o extract_v opium_n first_o out_o of_o water_n and_o afterward_o out_o of_o spirit_n of_o wine_n and_o then_o mix_v they_o together_o and_o evaporate_v they_o to_o a_o extract_n for_o this_o be_v as_o be_v say_v wise_o take_v care_n to_o add_v the_o poison_n to_o the_o panacea_fw-la or_o rosin_n extract_v by_o the_o spirit_n of_o wine_n to_o the_o sal-volatile-oleosum_a extract_v by_o the_o water_n beside_o the_o impair_v and_o loss_n make_v of_o the_o sal-volatile-oleosum_a by_o the_o spirit_n of_o wine_n and_o the_o evaporation_n how_o gentle_a soever_o it_o be_v here_o it_o will_v be_v seasonable_a to_o note_v that_o there_o be_v a_o general_a great_a fault_n commit_v by_o preparer_n of_o medicament_n especial_o such_o as_o pretend_v to_o most_o curiosity_n therein_o in_o endeavour_v right_a or_o wrong_n to_o have_v all_o the_o principle_n of_o the_o plant_n etc._n etc._n join_v together_o in_o their_o medicament_n however_o noxious_a or_o contrary_a to_o the_o purpose_n as_o you_o see_v in_o the_o instance_n just_o now_o mention_v whereas_o they_o have_v much_o better_o do_v as_o the_o great_a helmont_n say_v pharm_n &_o dispen_v modern_a 12._o saâ—guinem_fw-la a_o cruore_fw-la &_o parenâ—hymale_a plantarum_fw-la distinguere_fw-la &_o separare_fw-la discant_fw-la tyrones_n si_fw-la quicquam_fw-la laud_fw-la dignum_fw-la per_fw-la simplicia_fw-la egisse_fw-la meditentur_fw-la that_o be_v let_v beginner_n learn_v to_o distinguish_v and_o separate_v the_o true_a blood_n of_o plant_n from_o their_o cruor_fw-la or_o dead_a gore_n and_o parenchyma_n if_o they_o think_v to_o do_v any_o thing_n praiseworthy_a by_o simple_n you_o will_v find_v this_o to_o be_v very_o pat_o in_o the_o true_a preparation_n of_o the_o sal-volatile-oleosum_a who_o ruby-colour_n make_v it_o look_v like_a blood_n while_o the_o rosin_n earth_n and_o dross_n make_v the_o appearance_n of_o a_o dull_a and_o dead_a cruor_fw-la or_o gore_n if_o they_o take_v a_o tincture_n of_o opium_n in_o spirit_n of_o wine_n and_o use_v it_o so_o it_o will_v not_o be_v so_o bad_a for_o then_o the_o resinous_a particle_n be_v disseminated_a and_o not_o so_o liable_a to_o coalescence_n at_o stomach_n but_o so_o great_a be_v the_o stupidity_n that_o they_o take_v care_n by_o reduce_v it_o into_o the_o form_n of_o a_o extract_n to_o combine_v they_o and_o make_v they_o as_o noxious_a as_o be_v possible_a and_o then_o they_o think_v they_o worthy_a to_o be_v boast_v of_o as_o their_o nostrum_n
proclaim_v their_o ignorance_n and_o glory_v in_o their_o great_a shame_n and_o disgrace_n of_o mankind_n that_o humane_a species_n shall_v have_v any_o such_o unthinking_a brute_n in_o it_o iv_o we_o must_v not_o use_v acid_n in_o the_o preparation_n thereof_o 1._o because_o be_v in_o their_o nature_n opposite_a to_o volatile_a salt_n it_o can_v be_v do_v without_o injury_n to_o the_o sal-volatile-oleosum_a of_o opium_n 2._o because_o they_o can_v so_o well_o agree_v with_o the_o oily_a part_n of_o it_o yet_o be_v they_o not_o so_o much_o to_o be_v blame_v as_o extract_n make_v in_o spirit_n of_o wine_n or_o sulphureous_a menstruum_n because_o acid_a menstruum_n leave_v the_o rosin_n behind_o they_o untouched_a or_o not_o extract_v v._o a_o salino-volatile_a menstruum_fw-la as_o spirit_n of_o sal_fw-la ammoniac_a of_o urine_n etc._n etc._n be_v not_o so_o proper_a 1._o it_o may_v render_v the_o sal-volatile-oleosum_a of_o opium_n too_o acrimonious_a 2._o because_o by_o its_o volatility_n acrimony_n etc._n etc._n it_o may_v cause_v too_o great_a a_o stir_n in_o the_o blood_n etc._n etc._n and_o so_o oppose_v or_o hinder_v sleep_n which_o be_v one_o of_o the_o most_o happy_a and_o useful_a effect_n of_o opium_n or_o it_o be_v sal-volatile-oleosum_a 3._o because_o it_o may_v have_v undue_a effect_n by_o alter_v its_o general_a disposition_n nay_o vi_o we_o be_v not_o to_o use_v a_o lixivial_a menstruum_fw-la though_o so_o much_o cry_v up_o 1._o because_o it_o extract_v the_o resinous_a part_n which_o experto_fw-la crede_fw-la roberto_n i_o have_v find_v to_o be_v pernicious_a upon_o that_o account_n like_o extract_n in_o spirit_n of_o wine_n unless_o great_a care_n be_v take_v to_o separate_v those_o part_n which_o be_v not_o easy_o do_v by_o filtration_n etc._n etc._n 2._o because_o be_v very_o apt_a to_o join_v with_o the_o oily_a part_n and_o quite_o to_o destroy_v their_o nature_n by_o convert_v it_o into_o a_o kind_n of_o sapo_n it_o may_v deal_v so_o with_o some_o of_o the_o oily_a part_n of_o the_o sal-volatile-oleosum_a of_o opium_n 3._o because_o there_o be_v no_o need_n to_o run_v any_o of_o these_o hazard_n since_o the_o sal-volatile-oleosum_a may_v be_v as_o i_o shall_v show_v easy_o extract_v in_o its_o purity_n without_o those_o trouble_n and_o danger_n 4._o because_o any_o tincture_n make_v thus_o be_v apt_a to_o let_v go_v the_o rosin_n at_o stomach_n if_o it_o be_v dilute_v with_o aqueous_a moisture_n take_v before_o with_o it_o or_o after_o it_o which_o so_o be_v let_v go_v coalesces_fw-la and_o do_v mischief_n vii_o the_o use_n of_o fire_n any_o way_n beside_o that_o of_o its_o torrefaction_n be_v much_o to_o be_v suspect_v 1._o because_o the_o sal-volatile-oleosum_a may_v be_v in_o some_o measure_n thereby_o evaporate_v or_o 2._o an_fw-mi empyreum_fw-la contract_v and_o 3._o the_o rosin_n as_o be_v say_v of_o its_o torrefaction_n grow_v the_o more_o in_o proportion_n if_o any_o of_o the_o sal-volatile-oleosum_a or_o but_o the_o phlegm_n be_v by_o that_o mean_n evaporate_v and_o the_o remainder_n keep_v for_o use_v and_o particular_o viii_o the_o distillation_n thereof_o may_v cause_v mighty_a alteration_n in_o its_o property_n strength_n etc._n etc._n we_o must_v therefore_o avoid_v all_o these_o way_n of_o prepare_v it_o and_o yet_o must_v we_o 1._o separate_a the_o sal-volatile-oleosum_a of_o opium_n from_o all_o its_o rosin_n earth_n filth_n and_o dross_n 2._o no_o way_n weaken_v it_o alter_v it_o or_o add_v new_a quality_n thereto_o but_o preserve_v this_o most_o noble_a and_o inestimable_a medicament_n in_o its_o purity_n and_o sincerity_n to_o this_o end_n rain_n water_v distil_v use_v cold_a answer_v all_o intent_n for_o 1._o it_o ready_o imbibe_v the_o sal-volatile-oleosum_a of_o opium_n without_o fire_n heat_v lixivial_a salt_n as_o salt_n of_o tartar_n etc._n etc._n 2._o it_o imbibe_v none_o of_o the_o rosin_n of_o the_o opium_n but_o let_v it_o all_o subside_n together_o with_o the_o earthy_a and_o drossy_a part_n separate_v the_o light_a filth_n if_o there_o be_v any_o to_o the_o surface_n 3._o it_o no_o way_n weaken_v alter_v or_o add_v any_o new_a quality_n to_o the_o sal-volatile-oleosum_a 4._o whatever_o cold_a water_n dissolve_v which_o be_v the_o general_n drink_v or_o menstruum_fw-la appoint_v by_o the_o alwise_a creater_n for_o the_o dissolution_n of_o all_o thing_n take_v into_o the_o stomach_n of_o animal_n be_v easy_o dissolve_v at_o stomach_n by_o its_o more_o powerful_a and_o agreeable_a menstruum_fw-la and_o not_o only_o so_o but_z 5._o water_n itself_o be_v a_o mighty_a stomachick_n and_o causer_n of_o digestion_n as_o hypocrates_n positive_o declare_v l._n 6._o epidem_fw-la sect._n 4._o but_o there_o be_v no_o need_n of_o quote_v hypocrates_n in_o so_o notorious_a a_o thing_n daily_a experience_n tell_v we_o the_o same_o do_v not_o all_o animal_n by_o its_o help_n digest_v their_o food_n do_v not_o all_o mineral_n water_n scarce_o any_o except_v create_v a_o appetite_n and_o cause_n digestion_n even_o when_o no_o such_o effect_n can_v be_v attribute_v to_o the_o mineral_n they_o contain_v than_o which_o they_o do_v also_o as_o may_v be_v very_o easy_o prove_v more_o good_a general_o speak_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d for_o which_o and_o many_o more_o reason_n it_o be_v great_a neglect_n and_o folly_n that_o it_o be_v not_o more_o use_v for_o extract_n etc._n etc._n for_o then_o they_o ready_o dissolve_v at_o stomach_n and_o thereby_o 〈◊〉_d and_o speedy_o take_v effect_n give_v it_o the_o least_o 〈◊〉_d and_o disturbance_n that_o may_v be_v as_o be_v experimental_o find_v in_o that_o of_o aloe_n scammony_n briony_n 〈◊〉_d agariâ—_n 〈◊〉_d coloquintida_n sena_n and_o what_o not_o unless_o the_o virtue_n lie_v in_o the_o resinous_a parâ—s_n for_o then_o sulphureous_a or_o lixivial_a menstruum_n be_v convenient_a how_o inconvenient_a be_v they_o then_o when_o the_o evil_a or_o mischief_n lie_v therein_o as_o in_o our_o case_n 6._o it_o be_v not_o to_o be_v doubt_v but_o water_n general_o imbibe_v what_o be_v best_a and_o most_o agreeable_a to_o our_o body_n it_o be_v the_o general_n menstruum_fw-la appoint_v by_o wisdom_n itself_o for_o that_o use_v and_o to_o be_v the_o vehicle_n of_o what_o be_v best_a in_o all_o our_o food_n etc._n etc._n to_o the_o blood_n however_o there_o can_v be_v no_o doubt_n of_o what_o main_o concern_v we_o at_o present_a its_o most_o ready_a dissolve_v our_o panacea_fw-la in_o the_o stomach_n that_o do_v it_o out_o of_o it_o when_o cold_a without_o the_o convenient_a digestive_a heat_n and_o powerful_a menstruum_fw-la that_o it_o find_v there_o therefore_o take_v of_o distil_a rain-water_n 24_o ounce_n of_o choice_a opium_n slice_v thin_a 8_o ounce_n put_v they_o together_o in_o a_o strong_a glass_n vessel_n of_o bottle-metal_n that_o contain_v about_o 3_o piâ—ts_n let_v it_o be_v of_o a_o tall_a figure_n with_o a_o mouth_n that_o convenient_o receive_v a_o cork_n a_o large_a glass_n bottle_n may_v serve_v the_o turn_n cork_n it_o so_o as_o the_o cork_n may_v be_v easy_o take_v out_o shake_v it_o 3_o or_o 4_o time_n a_o day_n for_o 6_o day_n and_o keep_a it_o in_o a_o place_n free_a from_o frost_n or_o any_o very_a sensible_a degree_n of_o heat_n which_o be_v perform_v lie_v the_o vessel_n side-long_a for_o 24_o hour_n long_o and_o afterward_o decant_v and_o filter_n your_o tincture_n which_o will_v be_v of_o a_o ruby_n colour_n and_o put_v it_o into_o a_o glass_n bottle_n of_o such_o a_o bigness_n as_o that_o it_o may_v fill_v it_o within_o a_o small_a matter_n of_o the_o cork_n and_o so_o let_v it_o stand_v for_o 3_o or_o 4_o day_n then_o poâ—r_v off_o some_o of_o the_o surface_n of_o it_o and_o instead_o thereof_o put_v sweet_a oil_n thereon_o let_v the_o vessel_n have_v a_o convenient_a dust_n or_o pipe_n in_o the_o side_n thereof_o to_o empty_v it_o out_o upon_o occasion_n this_o i_o call_v the_o liquid_a panacea_fw-la of_o opium_n to_o the_o faeces_fw-la add_v a_o pint_n of_o cold_a distil_a water_n shake_v the_o vessel_n as_o before_o 3_o or_o 4_o time_n in_o the_o day_n let_v it_o stand_v on_o it_o 24_o hour_n and_o in_o the_o morning_n decant_v it_o into_o another_o vessel_n repeat_v the_o same_o quantity_n of_o distil_a rain-water_n till_o the_o opium_n no_o long_o tinge_v it_o or_o very_o inconsiderable_o in_o 24_o hour_n at_o last_o you_o may_v use_v water_n keep_v hot_a by_o a_o fire_n &c_n &c_n the_o better_a to_o extract_v the_o remain_v sal-volatile-oleosum_a evaporate_v all_o these_o last_o water_n in_o balneo_fw-la to_o the_o consistence_n of_o a_o extract_n this_o i_o call_v the_o solid_a panacea_fw-la of_o opium_n god_n and_o nature_n act_v by_o simple_a mean_n and_o nothing_o in_o imitation_n of_o they_o be_v more_o commendable_a in_o a_o medicament_n than_o simplicity_n therefore_o i_o shall_v add_v nothing_o to_o the_o panacea_n but_o whole_o
its_o stay_n or_o indigestibleness_n all_o regard_n must_v be_v have_v in_o the_o preparation_n thereof_o as_o be_v in_o the_o follow_a preparation_n which_o be_v therefore_o safe_a chap._n xxvii_o show_v the_o best_a preparation_n of_o opium_n where_o to_o find_v they_o and_o what_o be_v their_o respective_a dose_n etc._n etc._n you_o may_v infer_v out_o of_o the_o premise_n which_o be_v the_o best_a preparation_n of_o opium_n viz._n 1._o such_o as_o have_v the_o resinous_a part_n of_o opium_n separate_v from_o they_o as_o 1._o the_o liquid_a panacea_fw-la of_o opium_n describe_v in_o c._n 25._o of_o this_o book_n 2._o the_o solid_a panacea_fw-la of_o opium_n describe_v in_o c._n 25._o of_o this_o book_n 3._o diacodium_fw-la or_o sir_n e_o mecon_fw-mi in_o the_o london_n dispensatory_a 4._o laudanum_n liquidum_fw-la cydoniatum_n in_o experience_a mr._n wilson_n chemistry_n and_o in_o curious_a mr._n staphurst_n officina_fw-la chymica_fw-la londinensis_fw-la note_v that_o there_o be_v several_a needless_a proceed_n in_o this_o preparation_n as_o that_o of_o put_v yeast_n to_o it_o etc._n etc._n let_v your_o aim_n in_o make_v it_o be_v to_o separate_v the_o resinous_a part_n therefore_o instead_o of_o two_o expression_n direct_v use_v only_o a_o careful_a decantation_n because_o the_o rosin_n may_v pass_v by_o express_v it_o 5._o wedelius_n laudanum_n which_o be_v his_o opilogia_n l._n 1._o sect._n 2._o cap._n 2._o p._n 65._o note_v that_o the_o spumou_n part_v on_o the_o surface_n be_v to_o be_v take_v off_o and_o the_o clear_a tincture_n to_o be_v decant_v from_o the_o faeces_fw-la and_o afterward_o evaporate_v in_o balneo_fw-la to_o the_o consistence_n of_o a_o extract_n 6._o le_fw-fr mort's_n extract_n out_o of_o rain-water_n which_o you_o have_v in_o the_o most_o learned_a dr._n love_n collectanea_fw-la chymica_fw-la p._n 304._o ii_o such_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n be_v alter_v and_o as_o it_o be_v soapify_v by_o lixivial_a salt_n or_o soaps_o viz._n 1._o dr._n starkey_n or_o matthews_n piâ—l_o which_o you_o have_v in_o mr._n wilson_n chemistry_n p._n 271_o 272._o in_o ingenious_a mr._n shipton_n pharmacopâ—ia_n bateana_n among_o the_o pill_n and_o in_o mr._n staphurst_n officina_fw-la chymica_fw-la londinensis_fw-la among_o the_o laudanum_n p_o 51._o note_v that_o the_o main_a thing_n to_o be_v regard_v in_o 〈◊〉_d make_v up_o of_o this_o pill_n be_v 1._o to_o spare_v no_o labour_n in_o pound_v subdue_a and_o intimate_o mix_v the_o sapo_n tartareus_fw-la and_o the_o opium_n 2._o that_o the_o sapo_n shall_v be_v twice_o as_o much_o as_o the_o opium_n that_o it_o may_v the_o better_o subdue_v the_o resinous_a part_n of_o the_o opium_n note_v that_o as_o to_o the_o other_o thing_n contain_v in_o the_o â—aid_a pill_n they_o may_v or_o other_o thing_n be_v add_v or_o omit_v according_a to_o the_o intention_n of_o the_o physician_n only_o this_o i_o say_v that_o it_o be_v very_o convenient_a other_o thing_n shall_v be_v add_v to_o the_o sapo_n and_o opium_n the_o better_a to_o separate_v and_o disgregate_v the_o part_n of_o the_o opium_n as_o have_v be_v intimate_v note_v that_o if_o the_o mass_n be_v too_o dry_a you_o may_v as_o mr._n wilson_n direct_v use_v some_o of_o the_o oil_n that_o separate_v from_o the_o soap_n or_o rectify_v oil_n of_o turpentine_n q._n s._n to_o moisten_v it_o 2._o dr._n bates_n pacific_a pill_n which_o you_o have_v among_o the_o pill_n in_o mr._n shipton_n pharmacopâ—ia_n bateana_n note_v that_o the_o same_o thing_n be_v to_o be_v observe_v as_o to_o this_o and_o starkey_n pill_n in_o all_o particular_n note_v that_o the_o benjamin_n shall_v be_v omit_v as_o be_v resinous_a iii_o such_o preparation_n of_o opium_n wherein_o its_o resinous_a part_n remain_v unaltered_a in_o themselves_o yet_o so_o divide_v separate_a etc._n etc._n as_o to_o be_v render_v innocent_a such_o be_v all_o which_o you_o have_v in_o the_o london_n dispensatory_a 1._o venice_n treacle_n 2._o philoneum_fw-la persicum_fw-la 3._o philoneum_fw-la romanum_fw-la 4._o diascordiuâ—_n 5._o mithridate_n note_v that_o in_o all_o these_o preparation_n the_o opium_n shall_v be_v careful_o mix_v with_o the_o other_o ingredient_n and_o to_o that_o end_n either_o torrify_v and_o fine_o powder_v or_o dissolve_v in_o water_n which_o divide_v all_o its_o part_n and_o then_o thorough_o mix_v with_o the_o other_o ingredient_n while_o it_o be_v off_o or_o after_o it_o be_v reduce_v by_o evaporation_n to_o the_o consistence_n of_o a_o syrup_n or_o somewhat_o thin_a 6._o sydenbam_n laudanum_n which_o you_o will_v find_v in_o mr._n wilson_n chemistry_n note_v that_o the_o main_a care_n in_o this_o preparation_n be_v to_o let_v the_o liquor_n have_v a_o sufficient_a time_n to_o clear_v from_o the_o fâ—ces_n and_o to_o separate_v from_o it_o that_o you_o may_v by_o that_o mean_n have_v less_o of_o the_o rosin_n note_v that_o this_o be_v best_a give_v in_o a_o spirituous_a liquid_a lest_o its_o rosin_n though_o it_o can_v have_v much_o in_o it_o if_o well_o decant_v be_v precipitate_v at_o stomach_n note_v that_o the_o henbane-seed_n in_o the_o philonium_n shall_v be_v leave_v out_o 1._o because_o it_o make_v the_o do_v more_o uncertain_a 2._o because_o it_o be_v not_o to_o be_v esteem_v so_o much_o as_o opium_n at_o least_o you_o multiply_v thing_n without_o necessity_n in_o put_v it_o in_o note_v that_o pil._n e_fw-la cynoglosso_fw-la as_o be_v say_v in_o the_o last_o chapter_n of_o pil._n e_o styrace_n be_v a_o very_a ill_a composition_n both_o upon_o the_o account_n of_o the_o resinous_a thing_n that_o it_o contain_v as_o also_o the_o resinous_a preparation_n of_o opium_n that_o it_o be_v make_v of_o and_o therefore_o do_v as_o that_o e_z styrace_n often_o cause_v grievous_a effect_n nor_o do_v i_o think_v the_o london_n laudanum_n who_o name_n do_v probable_o recommend_v it_o more_o than_o any_o thing_n else_o worthy_a a_o place_n among_o the_o best_a and_o safe_a preparation_n because_o the_o opium_n be_v render_v worse_o or_o more_o resinous_a than_o the_o crude_a by_o be_v extract_v out_o of_o spirit_n of_o wine_n and_o because_o it_o have_v too_o few_o other_o ingredient_n to_o divide_v segregate_v and_o keep_v its_o resinous_a part_n from_o coalescence_n so_o that_o it_o may_v and_o sometime_o do_v cause_n ill_a symptom_n so_o philonium_fw-la magistrale_fw-la be_v to_o be_v reject_v for_o the_o like_a reason_n beside_o that_o it_o be_v otherwise_o a_o foolish_a preparation_n because_o opium_n benjamin_n myrrh_n and_o mummy_n be_v order_v to_o be_v make_v a_o opiate_n or_o electuary_n with_o spirit_n of_o wine_n which_o be_v ridiculous_a so_o troch_v the_o carabe_n and_o de_fw-fr terra_fw-la lemnia_n be_v not_o without_o their_o fault_n because_o one_o have_v frankincense_n and_o the_o other_o olibanum_fw-la in_o it_o which_o be_v resinous_a though_o but_o in_o a_o small_a quantity_n seif_n de_fw-mi thure_z have_v a_o great_a quantity_n of_o the_o frankincense_n be_v not_o commendable_a since_o the_o opium_n be_v also_o crude_a now_o have_v show_v you_o which_o be_v the_o best_a and_o worst_a preparation_n and_o why_o it_o remain_v that_o i_o show_v you_o the_o just_a dose_n of_o the_o best_a and_o soft_a who_o number_n be_v very_o sufficient_a to_o answer_v all_o intent_n without_o meddle_v with_o such_o as_o may_v not_o be_v so_o saâ—e_v or_o neat_a a_o explanation_n of_o the_o table_n of_o dose_n i_o have_v once_o add_v a_o explicatory_a table_n of_o the_o mark_v i_o use_v but_o afterward_o consider_v that_o all_o physician_n and_o good_a practitioner_n in_o physic_n do_v know_v they_o and_o that_o it_o be_v not_o fit_a to_o intrust_v other_o therewith_o therefore_o i_o shall_v only_o add_v something_o for_o the_o better_a and_o ready_a use_n of_o the_o premise_a table_n of_o dose_n 1._o note_v that_o the_o sort_n of_o person_n that_o you_o have_v to_o deal_v with_o be_v place_v in_o the_o uppermost_a space_n of_o the_o say_a table_n and_o the_o dose_n fit_a for_o such_o and_o such_o person_n put_v direct_o under_o they_o in_o the_o same_o column_n 2._o note_v that_o there_o be_v three_o sort_n of_o dose_n of_o every_o particular_a preparation_n that_o be_v the_o least_o middle_a and_o high_a do_v under_o every_o sort_n of_o man_n or_o woman_n which_o be_v also_o of_o three_o sort_n the_o strong_a middling_a and_o weak_a as_o you_o see_v in_o the_o upper_a space_n 3._o note_v therefore_o that_o when_o yond_o be_v about_o to_o give_v a_o opiate_n to_o any_o man_n or_o woman_n that_o you_o first_o look_n in_o that_o upper_a space_n for_o the_o sort_n of_o person_n you_o be_v to_o give_v it_o to_o as_o weak_a strong_a or_o middling_a man_n or_o woman_n then_o carry_v your_o eye_n down_o in_o that_o column_n till_o you_o come_v over_o against_o the_o preparation_n that_o you_o intend_v to_o give_v and_o there_o you_o will_v find_v in_o
the_o first_o symptom_n of_o a_o nausea_n vomit_v etc._n etc._n be_v most_o to_o be_v depend_v upon_o for_o it_o may_v happen_v sometime_o as_o after_o a_o great_a do_v that_o the_o rosin_n may_v stick_v etc._n etc._n and_o the_o relaxation_n be_v excessive_a also_o second_o when_o you_o be_v satisfy_v that_o it_o be_v the_o rosin_n at_o stomach_n that_o cause_v the_o mischief_n and_o not_o bare_a relaxation_n you_o be_v not_o to_o promote_v or_o stop_v the_o vomit_n lest_o in_o the_o first_o case_n you_o torment_n and_o endanger_v the_o person_n to_o no_o purpose_n for_o the_o rosin_n do_v general_o if_o not_o always_o stick_v too_o fast_o and_o too_o little_a in_o bulk_n to_o be_v shake_v off_o by_o vomit_v or_o the_o contraction_n of_o the_o stomach_n as_o appear_v by_o the_o tidious_a vomit_n that_o happen_v thereupon_o and_o the_o nature_n of_o the_o thing_n so_o that_o i_o believe_v it_o be_v seldom_o or_o never_o carry_v off_o that_o way_n and_o that_o when_o people_n be_v at_o last_o relieve_v it_o be_v by_o a_o gradual_a waste_n dissolution_n or_o digestion_n of_o the_o rosin_n as_o in_o great_a measure_n appear_v also_o by_o its_o purge_v some_o person_n after_o vomit_v and_o a_o long_a time_n after_o it_o be_v take_v in_o a_o considerable_a quantity_n nor_o be_v you_o to_o stop_v the_o vomit_v as_o not_o know_v what_o nature_n may_v advantage_n herself_o thereby_o but_o indeed_o it_o be_v more_o than_o you_o can_v do_v general_o speak_v if_o not_o always_o while_o the_o rosin_n teaze_v urge_v and_o sting_v the_o stomach_n it_o evident_o follow_v that_o the_o cure_n must_v consist_v in_o the_o dissolution_n of_o the_o rosin_n for_o this_o purpose_n you_o have_v four_o effectual_a dissolver_n of_o the_o rosin_n as_o you_o may_v observe_v from_o the_o chapter_n of_o the_o preparation_n of_o opium_n that_o may_v be_v use_v with_o safety_n in_o a_o moderate_a do_v 1._o lixivial_a salt_n whereof_o the_o best_a be_v salt_n of_o tartar_n 2._o sulphureous_a spirit_n whereof_o the_o best_a be_v high_a rectify_a spirit_n of_o wine_n 3._o the_o yolk_n of_o egg_n whereof_o the_o best_a be_v the_o yolk_n of_o a_o rear_n new_o lay_v egg._n 4._o white_a soap_n or_o rather_o the_o sapo_n tartareus_fw-la with_o these_o judicious_o use_v you_o may_v by_o god_n blessing_n relieve_v and_o cure_v the_o person_n grieve_v with_o the_o rosin_n or_o noxious_a part_n of_o opium_n 1._o give_v with_o all_o possible_a speed_n one_o scruple_n of_o salt_n of_o tartar_n in_o a_o spoonful_n or_o two_o of_o brandy_n or_o some_o other_o hot_a cordial_a spirit_n if_o spirit_n of_o wine_n be_v too_o hot_a place_v the_o person_n in_o the_o very_a same_o posture_n that_o he_o be_v in_o when_o he_o take_v the_o opiate_n that_o it_o may_v fall_v direct_o upon_o its_o rosin_n which_o most_o probable_o stick_v where_o the_o opiate_n first_o fall_v upon_o the_o coat_n of_o the_o stomach_n then_o stay_v for_o a_o minute_n or_o two_o and_o give_v a_o spoonful_n or_o two_o of_o the_o brandy_n or_o cordial_n with_o if_o need_v be_v the_o salt_n of_o tartar_n in_o it_o if_o you_o find_v cause_n either_o because_o the_o first_o dose_n be_v vomit_v or_o that_o the_o quantity_n of_o the_o rosin_n be_v great_a or_o that_o the_o person_n grow_v worse_a you_o may_v often_o repeat_v it_o for_o we_o must_v not_o be_v spare_v in_o safe_a thing_n in_o dangerous_a case_n i_o think_v it_o may_v well_o be_v repeat_v after_o every_o vomit_v toties_fw-la quoties_fw-la i_o have_v a_o great_a opinion_n of_o the_o yolk_n of_o a_o egg_n in_o these_o case_n not_o only_o because_o it_o do_v as_o the_o other_o thing_n mix_v with_o the_o rosin_n but_o because_o be_v of_o a_o good_a consistence_n it_o stick_v to_o it_o and_o fasten_v upon_o it_o the_o better_o and_o be_v not_o so_o clear_o shake_v from_o it_o by_o every_o vomit_n as_o liquid_n be_v therefore_o i_o think_v it_o very_o useful_a to_o be_v give_v now_o and_o then_o immediate_o after_o vomit_v however_o let_v no_o other_o food_n be_v give_v but_o it_o and_o be_v sure_a to_o use_v it_o when_o you_o have_v not_o the_o aforesaid_a thing_n i_o believe_v it_o will_v be_v find_v by_o experience_n which_o be_v yet_o much_o want_v because_o it_o have_v not_o be_v use_v to_o be_v the_o very_o best_a help_n in_o these_o case_n for_o the_o aforesaid_a reason_n and_o because_o its_o fine_a oiliness_n will_v correct_v the_o volatile_a salt_n of_o opium_n i_o can_v imagine_v but_o white_a soap_n or_o rather_o the_o sapo_n tartareus_fw-la if_o you_o have_v it_o by_o you_o may_v be_v of_o very_o good_a use_n to_o dissolve_v and_o carry_v off_o the_o rosin_n 2._o when_o the_o vomit_v begin_v to_o cease_v you_o must_v distinguish_v well_o whether_o it_o be_v because_o the_o person_n be_v better_a and_o the_o stomach_n discharge_v of_o the_o rosin_n or_o because_o tire_a nature_n yield_v itself_o to_o rest_n by_o a_o sort_n of_o succumbency_n to_o the_o fatigue_n or_o leipothymy_n you_o may_v easy_o distinguish_v these_o case_n for_o in_o the_o first_o case_n every_o thing_n seem_v better_a and_o in_o the_o last_o worse_o save_v that_o the_o vomit_v cease_v which_o be_v a_o endeavour_n of_o more_o vigorous_a nature_n and_o therefore_o its_o fail_n be_v now_o a_o ill_a sign_n in_o this_o case_n good_a old_a wine_n and_o spirituoâ—_n cordial_n which_o may_v rouse_v and_o invigorate_v nature_n and_o also_o engage_v with_o the_o rosin_n by_o their_o sulphureous_a spirit_n must_v be_v of_o excellent_a use._n note_v that_o if_o you_o want_v salt_n of_o tartar_n other_o lixivial_a salt_n may_v serve_v as_o those_o of_o wormwood_n broom_n etc._n etc._n only_o you_o must_v give_v at_o least_o one_o three_o more_o and_o in_o case_n of_o great_a haste_n and_o urgency_n you_o may_v give_v the_o very_a ash_n of_o wormwood_n broom_n or_o any_o vegetable_a in_o 2_o or_o 3_o time_n the_o quantity_n as_o the_o salt_n be_v to_o be_v give_v in_o 2_o or_o 3_o spoonful_n of_o brandy_n or_o a_o glass_n of_o old_a wine_n or_o both_o mix_v together_o for_o the_o very_a roughness_n of_o the_o ash_n will_v in_o some_o measure_n contribute_v to_o wear_v off_o the_o rosin_n and_o thereby_o assist_v the_o lixivial_a salt_n that_o be_v in_o they_o 3._o if_o the_o quantity_n of_o the_o resinous_n opium_n be_v great_a it_o will_v be_v convenient_a when_o you_o perceive_v the_o vomit_v begin_v to_o abate_v to_o give_v as_o much_o of_o daffee_n elixir_n or_o tinctura_fw-la sacra_fw-la make_v in_o some_o spirituous_a liquor_n as_o do_v usual_o give_v six_o stool_n it_o be_v best_o purge_v with_o a_o liquid_a because_o speedy_a in_o operation_n and_o that_o it_o shall_v be_v spirituous_a to_o help_v the_o dissolution_n of_o the_o rosin_n 1._o note_v that_o you_o also_o take_v care_v not_o to_o be_v too_o busy_a with_o spirituous_a liquor_n when_o they_o be_v much_o relax_v and_o have_v such_o symptom_n as_o drunken_a people_n have_v especial_o if_o they_o appear_v in_o a_o high_a degree_n for_o too_o much_o of_o they_o may_v promote_v the_o relaxation_n 2._o note_v that_o in_o faint_n or_o leipothymy_n after_o such_o vomit_n and_o struggle_v of_o nature_n you_o must_v not_o so_o much_o excite_v they_o by_o grievous_a sensation_n as_o pinch_v prick_a etc._n etc._n for_o those_o leipothymy_n be_v as_o be_v say_v a_o sort_n of_o recruit_v as_o sleep_n be_v and_o therefore_o the_o last_o refuge_n of_o nature_n for_o that_o end_n but_o with_o spirituous_a and_o comfortable_a thing_n as_o know_v that_o there_o be_v a_o awake_n by_o recruit_v which_o be_v natural_a as_o well_o as_o by_o grievous_a sensation_n which_o be_v force_v and_o unnatural_a as_o have_v be_v show_v ii_o to_o cure_v the_o effect_n of_o too_o much_o relaxation_n by_o a_o excessive_a do_v etc._n etc._n first_o you_o must_v be_v satisfy_v that_o the_o ill_a effect_n thereof_o be_v from_o too_o much_o relaxation_n 1._o by_o consider_v the_o preparation_n of_o opium_n that_o be_v take_v for_o if_o you_o find_v that_o it_o be_v such_o as_o have_v the_o rosin_n due_o separate_v from_o it_o you_o may_v be_v sure_a that_o the_o ill_a effect_n be_v only_o from_o relaxation_n because_o the_o do_v be_v too_o great_a or_o if_o it_o be_v a_o preparation_n that_o have_v the_o rosin_n so_o subdue_v or_o alter_v as_o you_o find_v direct_v to_o render_v it_o safe_a you_o may_v presume_v the_o ill_a effect_n be_v from_o over_o relaxation_n for_o such_o preparation_n be_v otherwise_o safe_a and_o innocent_a except_o when_o the_o largeness_n of_o the_o do_v as_o that_o of_o good_a wine_n cause_v too_o much_o relaxation_n 2._o by_o the_o symptom_n which_o be_v these_o viz._n alienation_n of_o the_o mind_n loss_n of_o memory_n stupidity_n sleepiness_n sopor_n failures_n of_o the_o sense_n as_o
darkness_n of_o the_o eye_n see_v thing_n double_a various_a colour_n before_o the_o eye_n loss_n of_o feel_v ease_n from_o pain_n etc._n etc._n deadness_n of_o the_o eye_n to_o the_o view_n dilatation_n of_o the_o pupilla_fw-la efflorescence_n of_o the_o skin_n laxity_n of_o the_o low_a jaw_n intumescence_n and_o laxity_n of_o the_o lip_n falter_v of_o the_o tongue_n sardonick_a laughter_n laxity_n and_o weakness_n of_o all_o part_n a_o general_a ineptitude_n to_o motion_n failure_n in_o make_v water_n go_v to_o stool_n and_o in_o all_o thing_n that_o require_v strength_n contraction_n motion_n etc._n etc._n difficulty_n of_o breathe_v a_o wide_a and_o slow_a pulse_n a_o condition_n in_o general_a very_a like_o that_o of_o drunkenness_n which_o also_o proceed_v from_o relaxation_n second_o when_o you_o be_v satisfy_v that_o relaxation_n be_v the_o cause_n use_v all_o mean_n to_o procure_v a_o due_a contraction_n of_o all_o part_n which_o be_v to_o be_v do_v 1._o by_o remove_v the_o cause_n of_o the_o relaxation_n 2._o by_o use_v all_o good_a mean_n for_o contraction_n first_o therefore_o give_v a_o brisk_a quick_a and_o strong_a vomit_n both_o to_o discharge_v the_o opiate_n and_o cause_n contraction_n of_o part_n by_o a_o grievous_a sensation_n proportion_n it_o to_o the_o deadness_n stupidity_n or_o sleepiness_n of_o the_o person_n so_o as_o to_o give_v it_o of_o twice_o the_o ordinary_a strength_n of_o vomit_n in_o case_n there_o be_v great_a danger_n from_o those_o symptom_n and_o that_o they_o be_v of_o a_o high_a nature_n after_o the_o person_n have_v vomit_v 3_o or_o 4_o time_n or_o so_o often_o as_o that_o you_o may_v judge_v the_o stomach_n well_o clear_v of_o the_o opiate_n give_v half_o a_o ounce_n of_o cream_n of_o tartar_n fine_o powder_v in_o thin_a broth_n whey_n water_n small_a beer_n or_o any_o convenient_a liquid_a which_o will_v correct_v the_o opiate_n if_o any_o remain_v at_o stomach_n turn_v the_o vomit_n to_o a_o purger_n to_o clear_v the_o intestine_n also_o and_o contribute_v much_o to_o the_o contraction_n of_o part_n which_o you_o must_v always_o have_v in_o your_o thought_n as_o the_o roll_a intention_n in_o this_o case_n therefore_o second_o you_o must_v use_v contracter_n all_o the_o time_n the_o chief_a of_o which_o be_v cold_a grievous_a sensation_n or_o pain_n terror_n fear_v voluntary_a motion_n and_o acid_n which_o last_n can_v be_v so_o well_o use_v during_o the_o vomit_v lest_o they_o stop_v it_o therefore_o especial_o if_o the_o person_n be_v very_o stupid_a keep_v he_o very_o cold_a for_o he_o will_v hardly_o feel_v it_o nor_o take_v cold_a because_o the_o relaxation_n and_o the_o insensibleness_n of_o grievance_n by_o cold_a etc._n etc._n keep_v the_o pore_n open_a let_v he_o be_v if_o possible_a in_o some_o motion_n as_o walk_v hew_v saw_v knock_v tug_v etc._n etc._n the_o more_o violent_a it_o be_v the_o better_a because_o it_o cause_v more_o contraction_n and_o agitation_n to_o prevent_v sopor_n to_o force_v he_o to_o motion_n if_o need_v be_v prick_a pinch_a or_o whip_v he_o about_o the_o leg_n etc._n etc._n will_v be_v of_o good_a use_n because_o grievous_a sensation_n add_v defensive_a contraction_n which_o be_v the_o great_a sort_n to_o that_o of_o the_o intentive_a contraction_n by_o voluntary_a motion_n these_o mean_n fail_v he_o shall_v be_v expose_v stark_o naked_a to_o the_o cold_a air_n and_o in_o desperate_a case_n throw_v sudden_o at_o unaware_o into_o cold_a water_n by_o which_o mean_v you_o cause_n terror_n surprise_v and_o cold_a which_o be_v the_o high_a and_o most_o forcible_a contracter_n to_o conspire_v to_o the_o contraction_n of_o part_n hence_o it_o be_v that_o drunken_a people_n who_o be_v so_o from_o relaxation_n become_v sober_a as_o in_o a_o moment_n by_o that_o mean_n all_o the_o time_n but_o during_o the_o vomit_v let_v he_o use_v cold_a acid_n in_o great_a plenty_n and_o very_o manifest_o acid_a for_o they_o will_v not_o only_o contribute_v to_o contraction_n but_o very_o much_o correct_v the_o opiate_n to_o this_o end_n juice_n of_o orange_n or_o lemon_n verjuice_n or_o water_n acidulate_v to_o a_o good_a degree_n by_o verjuice_n vinegar_n juice_n of_o lemon_n spirit_n of_o vitriol_n sulphur_n or_o the_o like_a will_v be_v very_o proper_a where_o you_o have_v not_o the_o convenience_n to_o plunge_v they_o into_o cold_a water_n as_o be_v direct_v dash_v or_o pump_v very_o cold_a water_n or_o water_n with_o a_o four_o part_n of_o vinegar_n upon_o their_o naked_a body_n will_v be_v of_o great_a use_n especial_o if_o surprise_o do_v to_o cause_v the_o more_o terror_n and_o concern_v these_o thing_n may_v be_v do_v more_o or_o lâ—ss_o as_o cause_n may_v require_v which_o must_v be_v leave_v to_o the_o discretion_n of_o the_o present_a physician_n or_o friend_n and_o standard_n by_o in_o case_n there_o be_v no_o physician_n i_o only_o caution_n that_o contracter_n shall_v not_o be_v use_v too_o spare_o and_o that_o you_o shall_v never_o cease_v to_o advance_v in_o the_o use_n of_o they_o till_o you_o perceive_v their_o good_a effect_n and_o then_o to_o continue_v they_o as_o occasion_n require_v note_v that_o the_o case_n may_v well_o happen_v that_o the_o rosin_n may_v stick_v at_o stomach_n and_o yet_o no_o sign_n or_o symptom_n appear_v but_o those_o of_o relaxation_n by_o reason_n that_o the_o feel_n at_o stomach_n may_v thereby_o be_v disable_v to_o take_v any_o notice_n of_o it_o to_o be_v sure_a of_o this_o you_o have_v no_o other_o mean_n because_o the_o symptom_n and_o effect_n of_o grievous_a sensation_n can_v appear_v where_o it_o be_v not_o for_o the_o aforesaid_a reason_n but_o to_o examine_v whether_o the_o opiate_n be_v a_o resinous_a one_o as_o crude_a opium_n extract_v out_o of_o spirit_n of_o wine_n or_o the_o like_a for_o than_o you_o may_v conclude_v especial_o if_o they_o be_v give_v in_o a_o massy_a solid_a form_n as_o that_o of_o pill_n etc._n etc._n without_o sever_n the_o particle_n of_o the_o rosin_n by_o other_o thing_n as_o the_o yolk_n of_o a_o egg_n etc._n etc._n that_o the_o rosin_n may_v in_o all_o probability_n stick_v at_o stomach_n though_o its_o symptom_n do_v not_o appear_v for_o the_o aforesaid_a reason_n in_o such_o a_o case_n the_o best_a advice_n that_o i_o can_v give_v be_v external_o to_o use_v all_o contract_n mean_v as_o be_v direct_v and_o internal_o the_o mean_v prescribe_v for_o dissolution_n of_o the_o rosin_n for_o you_o will_v thereby_o answer_v both_o intention_n failure_n of_o make_v water_n often_o happen_v in_o these_o case_n which_o you_o may_v general_o help_v by_o only_o clap_v the_o scrotum_fw-la to_o the_o cold_a chamber_n pot_n or_o into_o cold_a water_n and_o if_o that_o will_v not_o do_v put_v some_o vinegar_n into_o the_o water_n and_o that_o fail_v he_o must_v be_v strip_v and_o cold_a water_n pump_v or_o dash_v upon_o the_o region_n of_o the_o bladder_n iii_o to_o cure_v the_o ill_a effect_n of_o a_o long_a and_o lavish_a use_n of_o opium_n these_o effect_n as_o you_o may_v easy_o observe_v if_o you_o take_v a_o view_n of_o they_o where_o they_o be_v enumerate_v in_o chap._n 6._o be_v either_o 1._o from_o a_o overmuch_o and_o habitual_a relaxation_n of_o part_n as_o weakness_n a_o moapish_a disposition_n diminution_n of_o appetite_n weakness_n of_o digestion_n dropsy_n weakness_n of_o memory_n etc._n etc._n or_o 2._o from_o acrimony_n as_o frequent_a irritation_n to_o make_v water_n priapism_n erection_n of_o the_o penis_n fruitless_a inclination_n to_o venery_n etc._n etc._n in_o this_o case_n as_o in_o that_o of_o old_a drunkard_n which_o be_v much_o the_o same_o there_o be_v no_o good_a to_o be_v do_v till_o the_o habitual_a cause_n be_v remove_v viz._n the_o take_v of_o opium_n which_o sudden_o to_o leave_v off_o be_v as_o be_v show_v very_o dangerous_a therefore_o in_o order_n to_o leave_v it_o off_o safe_o 1._o you_o must_v stop_v your_o hand_n and_o not_o increase_v the_o do_v that_o be_v take_v by_o which_o mean_v it_o will_v come_v gradual_o to_o have_v little_a or_o no_o effect_n 2._o when_o you_o find_v that_o it_o be_v come_v to_o that_o pass_n your_o work_n be_v half_o do_v then_o only_o lessen_v it_o 100th_o part_n every_o day_n till_o you_o come_v to_o take_v none_o at_o all_o 3._o if_o during_o this_o retrograde_a course_n you_o find_v any_o faintness_n drink_v a_o glass_n of_o good_a stomach-wine_n toties_fw-la quoties_fw-la as_o gentian_n or_o centary_a wine_n or_o the_o like_a make_v by_o infusion_n in_o claret_n or_o if_o you_o want_v such_o a_o glass_n of_o the_o claret_n itself_o which_o thing_n will_v excite_v the_o spirit_n and_o help_v digestion_n 4._o when_o you_o have_v quite_o end_v the_o take_v of_o opium_n continue_v to_o use_v such_o wine_n when_o you_o be_v faint_a and_o every_o morning_n take_v in_o a_o glass_n of_o
gentian_a wine_n two_o dram_fw-la of_o the_o chalybeate_a wine_n describe_v in_o the_o london_n dispensatory_a increase_v about_o a_o scruple_n every_o day_n till_o you_o come_v to_o half_a a_o ounce_n which_o take_v for_o two_o month_n at_o least_o afterward_o decrease_v as_o you_o increase_v till_o you_o come_v to_o one_o drachm_n and_o so_o give_v over_o but_o if_o you_o find_v oâ—osion_n you_o may_v continue_v that_o course_n long_o or_o as_o long_o as_o your_o physician_n think_v fit_a after_o all_o you_o may_v use_v a_o glass_n of_o claret_n when_o faint_a but_o be_v sure_a to_o be_v moderate_a and_o not_o run_v from_o one_o excess_n to_o another_o as_o for_o the_o acrimony_n of_o blood_n that_o be_v more_o during_o the_o take_v of_o opium_n and_o will_v soon_o after_o gradual_o wear_v off_o especial_o by_o the_o course_n direct_v if_o not_o camphire_n be_v the_o adequate_a remedy_n of_o which_o with_o equal_a part_n of_o white_a rosin_n and_o q._n s._n of_o mucilage_n of_o gum._n tragac._n you_o may_v make_v pill_n of_o â—_o grain_n weight_n take_v 4_o of_o they_o every_o night_n at_o bedtime_n in_o a_o rear_n yolk_n of_o a_o egg_n as_o long_o as_o it_o be_v necessary_a for_o camphire_n by_o its_o fine_a sulphur_n correct_v the_o volatile_a acrimony_n of_o cantharides_n opium_n etc._n etc._n and_o so_o allay_v titillation_n to_o venery_n etc._n etc._n as_o be_v observe_v iv_o the_o ill_a effect_n of_o a_o sudden_a leave_v off_o of_o opium_n as_o anxiety_n distress_n depression_n of_o spirit_n which_o as_o be_v say_v be_v very_o dangerous_a be_v remedy_v no_o other_o way_n but_o either_o 1._o by_o return_v to_o the_o use_v of_o opium_n which_o be_v a_o most_o certain_a cure_n and_o afterward_o if_o you_o please_v give_v over_o the_o use_n of_o it_o after_o the_o manner_n that_o i_o direct_v which_o you_o will_v find_v to_o be_v safe_a nor_o can_v i_o advise_v you_o to_o trust_v any_o other_o method_n of_o leave_v it_o off_o unless_o it_o be_v 2._o by_o substitute_v wine_n instead_o of_o opium_n which_o be_v not_o quite_o so_o safe_a or_o certain_a your_o best_a method_n of_o use_v it_o be_v to_o drink_v a_o good_a glass_n of_o it_o so_o often_o as_o to_o keep_v the_o comfort_n thereof_o at_o stomach_n continual_o that_o so_o it_o may_v answer_v the_o more_o permanent_a effect_n of_o opium_n and_o keep_v you_o from_o a_o faint_a condition_n but_o see_v also_o that_o this_o course_n be_v not_o convenient_a to_o be_v continue_v long_o you_o must_v gradual_o lessen_v the_o do_v of_o this_o as_o you_o be_v direct_v to_o do_v that_o of_o opium_n till_o you_o come_v to_o take_v none_o or_o at_o least_o a_o moderate_a and_o wholesome_a quantity_n note_v that_o if_o such_o as_o use_v to_o take_v opium_n be_v even_o almost_o expire_a for_o want_n of_o it_o you_o must_v to_o prevent_v imminent_a death_n give_v a_o liquid_a preparation_n thereof_o to_o the_o value_n of_o what_o the_o person_n be_v use_v to_o take_v in_o a_o cordial_a vehicle_n as_o spirit_n of_o wine_n brandy_n or_o the_o like_a because_o such_o hot_a spirituous_a vehicles_n do_v as_o have_v be_v show_v immediate_o give_v some_o comfort_n by_o actuate_a and_o warm_v our_o spirit_n till_o the_o opium_n come_v to_o operate_v which_o will_v not_o be_v long_o because_o it_o be_v in_o a_o liquid_a form_n if_o you_o find_v the_o person_n sink_v notwithstanding_o he_o may_v be_v keep_v up_o by_o repeat_v the_o brandy_n or_o cordial_n without_o any_o opium_n in_o it_o till_o the_o opiate_n operate_v which_o will_v certain_o by_o god_n help_n set_v he_o right_n in_o case_n it_o do_v but_o begin_v to_o operate_v before_o he_o be_v dead_a see_v the_o philos._n transact_v for_o june_n july_n august_n 1696._o note_v that_o it_o be_v a_o very_a false_a imagination_n that_o author_n have_v of_o the_o turk_n capacity_n by_o nature_n climate_n or_o the_o like_a to_o take_v more_o opium_n or_o in_o great_a quantity_n than_o we_o may_v but_o that_o they_o make_v more_o use_n of_o it_o and_o by_o that_o mean_n come_v to_o take_v 2_o or_o 3_o dram_fw-la a_o day_n for_o they_o begin_v with_o such_o small_a quantity_n as_o we_o common_o give_v till_o by_o a_o long_a custom_n of_o take_v it_o they_o come_v to_o take_v the_o say_a quantity_n which_o be_v but_o small_a in_o comparison_n of_o what_o several_a english_a people_n that_o have_v be_v use_v to_o it_o do_v or_o have_v take_v as_o i_o can_v name_v several_a to_o you_o if_o i_o have_v not_o reason_n to_o the_o contrary_a however_o i_o be_o at_o liberty_n to_o tell_v you_o the_o quantity_n though_o i_o must_v forbear_v name_v the_o person_n some_o have_v daily_o take_v 2_o 3_o 4_o 5_o 6_o dram_fw-la nay_o i_o have_v hear_v of_o some_o that_o have_v take_v a_o ounce_n a_o day_n and_o of_o one_o that_o take_v two_o ounce_n whereas_o the_o learned_a and_o curious_a dr._n edward_n smith_n can_v find_v none_o about_o smyrna_n who_o take_v above_o 3_o dram_fw-la a_o day_n all_o this_o be_v most_o agreeable_a to_o reason_n and_o the_o whole_a current_n of_o my_o discourse_n viz._n that_o it_o can_v be_v better_o bear_v in_o cold_a than_o hot_a wether_n and_o consequent_o in_o cold_a than_o hot_a climate_n by_o firm_a flesh_v person_n than_o such_o as_o have_v soft_a and_o flaccid_a flesh_n as_o the_o southern_a people_n have_v in_o comparison_n of_o the_o northern_a and_o such_o as_o inhabit_v cold_a country_n therefore_o you_o may_v be_v sure_a that_o such_o as_o inquire_v into_o the_o cause_n why_o the_o turk_n and_o other_o eastern_a people_n can_v take_v great_a quantity_n than_o we_o can_v seek_v for_o the_o reason_n of_o thing_n before_o they_o know_v the_o fact_n nay_o when_o the_o fact_n be_v quite_o contrary_a to_o what_o they_o build_v upon_o we_o may_v as_o well_o expect_v edify_v discourse_n from_o they_o that_o inquire_v why_o fire_n be_v cold_a water_n dry_a and_o the_o like_a as_o from_o such_o as_o suppose_v thing_n contrary_a to_o true_a and_o sensible_a experience_n chap._n xxix_o some_o general_a rule_n caution_n &c_n &c_n concern_v the_o use_n of_o opium_n though_o there_o be_v hardly_o any_o rule_n caution_n or_o thing_n worthy_a of_o observation_n concern_v the_o use_n of_o opium_n but_o what_o be_v imply_v or_o easy_o inferable_a from_o what_o have_v be_v say_v nor_o now_o that_o the_o true_a nature_n of_o opium_n be_v discover_v can_v there_o be_v such_o fear_n and_o jealoufy_v which_o multiply_v caution_n concern_v the_o administration_n thereof_o for_o every_o one_o may_v now_o easy_o see_v wherein_o its_o danger_n and_o benefit_n lie_v yet_o because_o a_o chapter_n of_o rule_n and_o caution_n may_v be_v expect_v as_o be_v usual_a and_o to_o have_v a_o single_a view_n of_o such_o as_o lie_v more_o scatter_v and_o not_o so_o ready_o find_v in_o the_o body_n of_o the_o book_n i_o will_v to_o introduce_v the_o use_n of_o opium_n with_o more_o clearness_n and_o perfect_a security_n give_v you_o a_o collection_n of_o general_a rule_n and_o caution_n concern_v its_o use_n whereof_o some_o be_v mention_v and_o most_o inferable_a from_o the_o premise_n i._o as_o to_o its_o substance_n 1._o it_o shall_v be_v always_o give_v free_v from_o its_o resinous_n part_n if_o you_o can_v get_v such_o a_o preparation_n 2._o it_o be_v also_o neat_a and_o convenient_a that_o it_o shall_v be_v free_v from_o all_o its_o earth_n and_o dress_n 3._o never_o give_v opium_n but_o either_o so_o prepare_v or_o with_o its_o rosin_n so_o subdue_v segregated_a or_o alter_v as_o i_o have_v show_v in_o the_o safe_a preparation_n thereof_o iâ—_n follow_v that_o 4._o crude_a opium_n and_o extract_v make_v in_o sulphureous_a spirit_n be_v utter_o to_o be_v reject_v 5._o never_o give_v it_o mix_v or_o join_v with_o resinous_a thing_n as_o have_v be_v intimate_v 6._o never_o mix_v or_o join_v it_o with_o other_o opiate_n 1._o because_o none_o of_o they_o be_v so_o good_a 2._o because_o they_o be_v not_o so_o well_o know_v 3._o because_o it_o make_v the_o do_v more_o uncertain_a 4._o because_o those_o other_o opiate_n be_v use_v unprepared_a 7._o pil._n e_o styrace_n because_o make_v of_o resinous_a opium_n join_v with_o resinous_a thing_n as_o styrax_fw-la calam_fw-la and_o olibanum_n be_v a_o insufferable_a preparation_n though_o commend_v and_o therefore_o have_v frequent_a ill_a effect_n to_o my_o knowledge_n 8._o pil._n â—_o cynoglossâ_fw-la be_v such_o another_o have_v two_o opiate_n in_o it_o beside_o opium_n extract_v out_o of_o spirit_n of_o wine_n which_o be_v far_o worse_a than_o crude_a opium_n though_o by_o the_o way_n of_o eminence_n call_v opium_n prepare_v in_o our_o dispensatory_a styrax_n calam_fw-la and_o olibanum_n which_o be_v resinous_a 9_o laudan_n lond._n be_v also_o a_o ill_a preparation_n as_o have_v the_o
that_o when_o people_n be_v in_o a_o untoward_a condition_n or_o as_o they_o call_v it_o out_o of_o sod_n the_o next_o day_n after_o drink_v man_n often_o advise_v take_v the_o hair_n of_o the_o same_o dog_n that_o be_v drink_v some_o of_o the_o same_o wine_n or_o liquor_n it_o be_v best_o for_o they_o to_o use_v it_o as_o i_o just_a now_o direct_v for_o their_o case_n upon_o the_o good_a effect_n of_o the_o wine_n cease_v be_v much_o like_a that_o upon_o the_o go_n off_o of_o the_o operation_n of_o opium_n which_o may_v also_o in_o this_o case_n be_v use_v instead_o of_o wine_n to_o procure_v a_o better_a and_o blither_n condition_n for_o that_o day_n that_o use_v to_o be_v very_o troublesome_a to_o drinker_n 3._o note_v that_o good_a preparation_n of_o opium_n may_v be_v convenient_o use_v to_o horse_n to_o prevent_v their_o be_v tire_v or_o take_v off_o their_o weariness_n and_o cause_v they_o to_o go_v on_o but_o i_o will_v not_o advise_v any_o preparation_n in_o this_o case_n but_o the_o liquid_a panacea_fw-la in_o good_a ale_n or_o beer_n and_o that_o only_a in_o the_o same_o quantity_n as_o be_v use_v to_o man_n till_o far_a experience_n embolden_v the_o practice_n by_o such_o mean_n i_o can_v doubt_v it_o any_o jade_n may_v be_v make_v to_o appear_v lively_a go_v well_o etc._n etc._n chap._n xxxii_o of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o compose_v the_o sensitive_a soul_n spirit_n etc._n etc._n i_o have_v show_v how_o and_o why_o it_o compose_v and_o quiet_v the_o sensitive_a soul_n spirit_n blood_n stomach_n etc._n etc._n and_o by_o that_o mean_n allay_v all_o the_o fury_n commotion_n perturbation_n and_o turbulent_a exorbitance_n thereof_o and_o that_o often_o without_o sleep_n but_o much_o better_a with_o it_o it_o follow_v therefore_o 1._o that_o it_o prevent_v and_o take_v off_o all_o fret_n and_o turbulent_a passion_n of_o the_o sensitive_a soul_n as_o anger_n uneasy_a agitation_n and_o toss_v of_o the_o mind_n peevishness_n fretfulness_n discontent_n disquietude_n dissatisfaction_n murmur_n turmoiling_n and_o vexatious_a thought_n anxiety_n solicitude_n etc._n etc._n and_o all_o the_o evil_a effect_n thereof_o as_o watch_n waste_v of_o spirit_n or_o strength_n lossitude_n hypochondriacal_a melancholy_n cachexy_n scurvy_n etc._n etc._n but_o these_o last_o belong_v most_o proper_o to_o its_o alterative_a faculty_n or_o virtue_n 2._o all_o involuntary_a furious_a agitation_n of_o the_o sensitive_a soul_n and_o spirit_n as_o madness_n more_o especial_o melancholy_a madness_n or_o such_o as_o proceed_v from_o grievous_a thought_n or_o apprehension_n loss_n cross_n despair_n fear_n terror_n or_o the_o like_a but_o they_o be_v not_o so_o good_a in_o merry_a madness_n as_o those_o from_o joy_n venereal_a fury_n and_o suchlike_a which_o answer_v the_o great_a dispute_n about_o opiate_n in_o madness_n delirium_n epileptical_a fit_n convulsion_n general_a and_o particular_a as_o those_o of_o the_o head_n rise_v of_o the_o light_n vomit_n hiccough_n sabbing_n kecking_n convulsive_a asthma_n palpitation_n and_o tremble_n of_o the_o heart_n shake_v and_o shivering_n upon_o fear_n terror_n cold_a pain_n ague-fits_a convulsive_a colick_n hysterick_n fit_v iliack_a passion_n etc._n etc._n 3._o all_o fever_n and_o fret_n of_o humour_n that_o happen_v from_o any_o of_o the_o aforesaid_a cause_n or_o from_o any_o violent_a motion_n voluntary_a or_o involuntary_a as_o labour_n run_v hew_v fight_a or_o any_o vehement_a exercise_n ratling_n toss_n concussion_n in_o coach_n wagon_n boat_n in_o stormy_a wether_n violent_a ride_v etc._n etc._n or_o from_o heat_n of_o fire_n sun_n bath_n hothouse_n bagnio_n crowd_n lie_v too_o many_o in_o one_o bed_n or_o with_o too_o much_o clothes_n or_o from_o grievous_a sensation_n irritation_n or_o pain_n as_o fever_n upon_o inflammation_n abscess_n bubo_n stone_n colic_n cardialgia_n wound_n fracture_n dislocation_n confusion_n amputation_n lithotomy_n paracentesis_n or_o any_o painful_a operation_n of_o the_o noble_a art_n of_o chirurgery_n agony_n or_o pain_n of_o the_o smallpox_n as_o its_o second_o fever_n and_o the_o like_a or_o from_o flux_n as_o tedious_a and_o turbulent_a vomit_n diarrheas_n dysentery_n cholera_n iliack_a passion_n artificial_a purge_v and_o all_o symptomatick_a or_o immaterial_a fever_n whatsoever_o which_o either_o never_o have_v any_o matter_n but_o proceed_v from_o such_o agitate_a cause_n as_o i_o mention_v or_o remain_v as_o some_o do_v after_o the_o grieve_v matter_n be_v carry_v off_o by_o vomit_v purge_v etc._n etc._n i_o forbear_v mention_v pleurisy_n and_o peripneumonia_n among_o the_o fever_n that_o it_o prevent_v or_o take_v off_o because_o there_o be_v great_a dispute_n whether_o opiate_n be_v convenient_a in_o those_o case_n which_o i_o hope_v to_o determine_v unless_o it_o be_v when_o the_o say_v distemper_n be_v come_v to_o that_o pass_n that_o it_o be_v dangerous_a to_o cause_v sleep_n or_o take_v away_o any_o of_o the_o sense_n of_o the_o irritation_n of_o the_o matter_n to_o be_v expectorate_v lest_o it_o shall_v be_v too_o much_o amass_v in_o the_o bronchias_n or_o windpipe_n and_o so_o choke_v the_o person_n i_o see_v no_o cause_n to_o forbid_v they_o any_o more_o than_o sleep_v or_o opiate_n in_o other_o inflammation_n wherein_o they_o be_v high_o beneficial_a to_o give_v ease_n cause_n sleep_n compose_v the_o spirit_n and_o take_v off_o or_o at_o least_o moderate_a the_o fever_n but_o i_o see_v many_o good_a reason_n to_o use_v they_o 1._o because_o as_o a_o sal-volatile-oleosum_a they_o reserate_v and_o resolve_v clammy_a humour_n and_o be_v so_o agreeable_a in_o principle_n as_o menstraums_n shall_v be_v to_o the_o thing_n to_o be_v resolve_v i_o can_v doubt_v but_o red_a poppy_n be_v upon_o experience_n state_v a_o specific_a in_o those_o case_n for_o that_o reason_n 2._o because_o these_o distemper_n as_o hypocrates_n speak_v be_v from_o a_o segregation_n of_o humour_n by_o agitation_n etc._n etc._n and_o opiate_n excellent_a composer_n thereof_o 3._o because_o they_o be_v such_o great_a discusser_n and_o 4._o open_v the_o pore_n to_o let_v the_o discuss_v matter_n quite_o out_o of_o the_o body_n 5._o because_o it_o may_v be_v that_o by_o its_o relaxation_n upon_o such_o resolution_n the_o lodge_v matter_n may_v be_v cause_v to_o flow_v off_o and_o circulate_v again_o and_o so_o be_v gradue_v discuss_v and_o carry_v off_o by_o the_o open_a pore_n 6._o because_o it_o envigorate_v nature_n to_o perform_v those_o thing_n and_o 7._o give_v ease_n and_o recruit_v of_o the_o spirit_n by_o sleep_n so_o that_o all_o thing_n consider_v i_o think_v as_o experience_n assure_v we_o that_o red_a poppy_n or_o opiate_n in_o due_a quantity_n be_v the_o very_o best_a remedy_n that_o can_v be_v use_v hence_o it_o be_v that_o wedelius_n call_v opium_n a_o antipleuritick_n specific_a he_o have_v observe_v as_o i_o and_o other_o have_v do_v that_o the_o whole_a course_n of_o the_o disease_n and_o expectoration_n will_v succeed_v much_o better_a by_o their_o use._n he_o add_v also_o that_o he_o have_v very_o often_o cure_v they_o by_o its_o help_n without_o let_v of_o blood_n which_o be_v a_o infallible_a sign_n of_o their_o good_a effect_n since_o the_o pleurisy_n can_v hardly_o be_v cure_v without_o bleed_v i_o can_v see_v how_o a_o effect_n that_o bear_v such_o analogy_n to_o sleep_n can_v do_v any_o more_o harm_n than_o sleep_n etmuller_n also_o advise_v the_o give_v of_o opiate_n not_o only_o in_o the_o beginning_n but_o also_o during_o the_o increase_n of_o the_o pleurisy_n or_o peripneumoniae_fw-la so_o that_o i_o conclude_v that_o they_o be_v of_o excellent_a use_n in_o those_o disease_n unless_o it_o be_v when_o sleep_n or_o they_o may_v cause_v too_o much_o insensibleness_n of_o the_o bronchias_n and_o so_o retard_v expectoration_n when_o the_o case_n be_v such_o that_o the_o want_v thereof_o may_v endanger_v the_o person_n be_v be_v choke_v we_o have_v also_o many_o history_n of_o person_n cure_v in_o other_o fever_n by_o large_a dose_n of_o opiate_n i_o suppose_v that_o resinous_a opiate_n cause_v vomit_v and_o great_a disturbance_n by_o reason_n of_o ill_a digestion_n in_o those_o case_n may_v be_v one_o great_a cause_n of_o people_n fear_n and_o jeolousy_n in_o give_v opiate_n which_o be_v easy_o prevent_v by_o give_v liquid_a opiate_n void_a of_o any_o resinous_a particle_n as_o the_o liquid_a panacea_fw-la etc._n etc._n 4._o it_o do_v by_o compose_v quiet_v and_o appease_v the_o motion_n and_o perturbation_n of_o the_o blood_n conduce_v much_o to_o the_o stop_n of_o its_o efflux_n in_o hemorrhage_n or_o bleeding_n that_o be_v unnatural_a as_o at_o nose_n in_o spit_v and_o vomit_v of_o blood_n bleed_v at_o the_o hemorrhoid_v in_o dysentery_n piss_v of_o blood_n etc._n etc._n and_o sometime_o in_o profuse_a menses_fw-la when_o they_o happen_v from_o a_o fever_n or_o too_o much_o motion_n of_o the_o blood_n and_o
spirit_n and_o not_o a_o over-relaxation_n or_o dilatation_n of_o the_o pore_n which_o must_v be_v well_o distinguish_v i._o the_o form_n must_v be_v liquid_a in_o all_o fever_n and_o be_v also_o most_o convenient_a general_o speak_v ii_o the_o do_v may_v be_v the_o moderate_a or_o middling_a except_o it_o be_v where_o the_o pain_n be_v great_a or_o where_o much_o of_o the_o opiate_n be_v lose_v as_o in_o vomit_v looseness_n etc._n etc._n for_o which_o see_v the_o general_n rule_v iii_o the_o vehicle_n shall_v be_v general_o speak_v cool_v compose_v and_o incrassate_v liquid_n as_o emulsion_n milk_n and_o water_n or_o the_o like_a but_o in_o settle_v the_o stomach_n use_v agreeable_a warm_a and_o comfortable_a cordial_n or_o wine_n burn_v with_o aromatics_n or_o the_o like_a iv_o the_o time_n be_v when_o it_o be_v convenient_a according_a to_o the_o general_n rule_v and_o your_o intention_n of_o its_o operation_n therefore_o where_o there_o be_v periodical_a paroxysm_n or_o exacerbation_n as_o in_o the_o smallpox_n and_o many_o disease_n in_o the_o afternoon_n or_o towards_o the_o evening_n give_v it_o the_o due_a time_n before_o that_o it_o may_v have_v its_o full_a effect_n by_o the_o time_n the_o paroxysm_n or_o exacerbation_n be_v expect_v to_o begin_v and_o be_v not_o so_o mad_a as_o to_o be_v regulate_v by_o night_n or_o day_n or_o bedtime_n etc._n etc._n as_o be_v usual_a which_o be_v no_o symptom_n sign_n or_o effect_n of_o the_o distemper_n but_o of_o the_o motion_n or_o position_n of_o the_o sun_n star_n &c_n &c_n which_o be_v not_o the_o subject_n of_o your_o cure_n nor_o can_v be_v the_o want_n of_o which_o most_o obvious_a and_o rational_a practice_n have_v sad_o disappoint_v inconsiderate_a physician_n and_o often_o hazard_v if_o not_o destroy_v the_o patient_n v._o the_o regimen_n be_v the_o same_o as_o that_o to_o cause_v sleep_n which_o you_o have_v in_o chap._n 35._o and_o shall_v be_v by_o all_o mean_v use_v in_o this_o case_n 1._o note_v that_o opiate_n be_v not_o to_o be_v use_v as_o have_v be_v intimate_v where_o the_o commotion_n flux_n etc._n etc._n be_v for_o apparent_a and_o speedy_a benefit_n of_o nature_n as_o in_o vomit_v upon_o repletion_n or_o to_o discharge_v the_o stomach_n of_o somewhat_o that_o offend_v it_o or_o a_o looseness_n to_o clear_v the_o intestine_n or_o the_o like_a 2._o note_v that_o when_o any_o evacuation_n be_v to_o be_v make_v by_o vomit_n or_o stool_n the_o best_a way_n in_o these_o case_n be_v to_o use_v large_a dilution_n of_o some_o contemperate_a liquid_a instead_o of_o vomitory_n and_o purger_n therefore_o use_v only_o lukewarm_a water_n or_o which_o be_v best_a boil_v with_o a_o little_a carduus_fw-la in_o it_o or_o carduus-posset_n or_o the_o like_a to_o cause_v vomit_v and_o more_o agreeable_a dilution_n for_o the_o intestine_n to_o wash_v off_o ill_a humour_n as_o a_o gallon_n of_o water_n with_o half_a a_o ounce_n of_o cream_n of_o tartar_n or_o rather_o the_o purge_a salt_n of_o the_o water_n dissolve_v in_o it_o or_o some_o part_n thereof_o use_v all_o cold_a or_o but_o very_o little_o warm_v give_v the_o opiate_n or_o panacea_fw-la immediate_o after_o the_o person_n have_v do_v vomit_v or_o purge_v in_o a_o small_a glass_n of_o wine_n or_o agreeable_a cordial_n to_o warm_v and_o comfort_v the_o stomach_n and_o intestine_n which_o because_o of_o the_o smallness_n of_o the_o quantity_n the_o moisture_n and_o coolness_n of_o the_o dilute_a liquid_n and_o the_o opiate_n can_v cause_v no_o inconvenience_n by_o its_o inconsiderable_a heat_n chap._n xxxiii_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o relax_v have_v show_v that_o opiate_n relax_v all_o the_o sensile_a part_n of_o the_o body_n and_o bow_n and_o why_o it_o follow_v that_o they_o be_v of_o excellent_a use_n 1._o to_o prevent_v and_o take_v away_o all_o contraction_n that_o happen_v from_o grievous_a passion_n or_o sensation_n or_o pain_n as_o convulsion_n sâ—iverings_n shake_v cramp_n tension_n palpitation_n and_o tremor_n of_o the_o heart_n from_o fear_n terror_n grief_n melancholy_n anxiety_n solicitude_n anger_n fretfulness_n concern_v surprise_v etc._n etc._n or_o from_o cold_a pain_n acid_n etc._n etc._n as_o contraction_n of_o the_o sphincter_n of_o the_o bladder_n from_o those_o cause_n by_o which_o the_o urine_n be_v often_o stop_v as_o also_o by_o the_o pain_n from_o the_o haemorrhoid_v inflammation_n small_a pox_n colick_n acrimony_n excoriation_n etc._n etc._n which_o often_o hinder_v the_o make_n of_o water_n as_o they_o also_o do_v sometime_o go_v to_o stool_n swallow_v etc._n etc._n shiver_a in_o ague-fits_a stupor_n from_o cold_a or_o pain_v which_o as_o be_v show_v proceed_v from_o a_o violent_a contraction_n in_o all_o which_o it_o will_v scarce_o ever_o fail_v of_o due_a effect_n by_o this_o mean_v you_o may_v as_o i_o have_v often_o do_v cure_v those_o disaster_n safe_o speedy_o and_o pleasant_o even_o to_o a_o wonder_n and_o amazement_n as_o if_o charm_v by_o a_o spell_n when_o other_o know_v not_o what_o hand_n to_o put_v to_o they_o and_o be_v quite_o baffle_v thereby_o by_o the_o same_o mean_n though_o little_a or_o not_o at_o all_o mind_a you_o may_v prevent_v great_a tumor_n upon_o pain_n as_o when_o by_o a_o thorn_n or_o any_o grievous_a pain_n the_o arm_n leg_n thigh_n etc._n etc._n begin_v to_o swell_v for_o the_o swell_a which_o often_o grow_v prodigious_o and_o seize_v the_o whole_a limb_n if_o not_o a_o great_a part_n of_o the_o body_n threaten_v and_o often_o cause_v mortification_n and_o death_n itself_o be_v cause_v by_o the_o pain_n contract_v and_o so_o gird_v the_o part_n that_o the_o blood_n lympha_fw-la &c._n &c._n can_v pass_v by_o which_o mean_v the_o humour_n be_v stagnate_v and_o crowd_v in_o by_o the_o force_n of_o the_o artery_n and_o damn_v up_o by_o the_o contraction_n most_o dreadful_a tumor_n happen_v whereas_o the_o pain_n be_v take_v away_o by_o the_o opiate_n and_o all_o the_o part_n relax_v they_o be_v and_o must_v be_v prevent_v by_o plain_a mechanism_n if_o use_v timely_a for_o pain_n can_v cause_v tumor_n by_o no_o other_o mean_n beside_o contraction_n which_o opium_n must_v prevent_v by_o take_v away_o the_o very_a pain_n itself_o 2._o to_o help_v the_o cure_n of_o all_o other_o contraction_n as_o tension_n rigidity_n of_o nerve_n membrane_n tendon_n ligament_n muscle_n etc._n etc._n 3._o to_o relax_v or_o make_v way_n for_o thing_n to_o pass_v as_o sweat_v 〈◊〉_d small_a pox_n measles_n pestilential_a or_o venomous_a esslâ—vias_n mâ—nses_n lochia_n and_o the_o like_a to_o pass_v through_o the_o skin_n or_o pore_n a_o child_n dead_z or_o alive_a afterbirth_n mole_n clod_v blood_n etc._n etc._n to_o pass_v through_o the_o neck_n of_o the_o womb_n when_o too_o narrow_a by_o nature_n or_o contract_v by_o pain_n cold_a terror_n etc._n etc._n a_o stone_n to_o pass_v the_o ureter_n or_o neck_n of_o the_o bladder_n by_o take_v away_o the_o pain_n that_o contract_v they_o and_o hinder_v the_o passage_n of_o the_o stone_n so_o that_o in_o the_o hand_n of_o a_o ingenious_a physician_n there_o be_v not_o a_o better_a nor_o as_o good_a a_o remedy_n to_o cause_v a_o stone_n of_o any_o passable_a bigness_n to_o come_v away_o for_o it_o pass_v through_o the_o relaxed_a or_o widen_v passage_n without_o pain_n to_o help_v which_o other_o relaxer_n as_o warmth_n 〈◊〉_d bathâ—_n fomentation_n clyster_n together_o with_o slippery_a and_o emollient_a thing_n inward_o take_v and_o at_o last_o a_o great_a stream_n of_o urine_n well_o contrive_v and_o time_v when_o the_o part_n be_v most_o relax_v supple_v and_o lubricate_v do_v much_o conduce_v i_o will_v have_v all_o who_o be_v trouble_v with_o the_o stone_n note_v this_o note_v also_o that_o to_o hold_v and_o dam_v up_o the_o urine_n a_o long_a time_n be_v of_o excellent_a use_n well_o manage_v when_o the_o stone_n be_v in_o the_o ureter_n because_o when_o the_o urine_n have_v fill_v up_o the_o bladder_n very_o tight_o that_o it_o will_v receive_v no_o more_o it_o must_v distend_v the_o ureter_n which_o be_v the_o cause_n that_o very_o many_o be_v ease_v either_o by_o the_o removal_n or_o discharge_v of_o the_o stone_n after_o a_o set_a time_n which_o give_v occasion_n to_o call_v they_o fit_v of_o the_o stone_n because_o they_o last_o for_o much_o about_o the_o same_o length_n of_o time_n however_o the_o large_a and_o sudden_a evacuation_n of_o urine_n must_v by_o leave_v the_o part_n loose_a etc._n etc._n conduce_v very_o much_o to_o the_o passage_n of_o the_o stone_n clod_n of_o blood_n phlegm_n matter_n etc._n etc._n that_o step_v the_o urine_n 4._o to_o relax_v or_o make_v way_n for_o thing_n to_o be_v put_v into_o the_o body_n when_o there_o be_v occasion_n as_o in_o reduction_n of_o hernias_fw-la or_o rupture_n of_o a_o fall_v fundament_n womb_n or_o
vagina_n in_o which_o case_n it_o be_v of_o neat_a use_n both_o by_o relax_v and_o take_v away_o pain_n during_o the_o operation_n it_o may_v be_v also_o of_o use_n when_o the_o strictness_n of_o the_o collum_n uteri_fw-la hinder_v the_o admission_n of_o sem._n viril_n both_o as_o a_o general_a relaxer_n and_o as_o cause_v great_a pleasure_n of_o those_o part_n and_o a_o proportionable_a relaxation_n thereof_o for_o it_o be_v by_o the_o pleasure_n in_o coition_n that_o the_o collum_n uteri_fw-la be_v open_v or_o relax_v as_o be_v observe_v which_o immediate_o close_v again_o when_o the_o sense_n of_o pleasure_n be_v end_v yea_o and_o so_o much_o the_o strict_a because_o the_o loss_n of_o pleasure_n be_v as_o be_v show_v a_o kind_a of_o grievance_n hence_o it_o be_v that_o omne_fw-la animal_n post_fw-la coitum_fw-la est_fw-la triste_fw-fr and_o not_o because_o of_o loss_n of_o spirit_n as_o be_v vulgar_o imagine_v for_o we_o can_v lose_v little_a or_o no_o spirit_n by_o that_o which_o be_v so_o separate_v for_o excretion_n before_o hand_n as_o the_o semen_n be_v 5._o to_o enlarge_v any_o part_n for_o the_o due_a reception_n of_o what_o be_v convenient_a or_o necessary_a as_o the_o breast_n to_o receive_v milk_n by_o which_o mean_v it_o come_v to_o be_v such_o great_a increaser_n of_o milk_n the_o seminal_a vessel_n as_o sem._n virile_a do_v upon_o puberty_n to_o receive_v the_o semen_n thus_o it_o cause_v the_o penis_n to_o grow_v as_o the_o semen_n upon_o puberty_n cause_v it_o and_o cock_n comb_n turkeycock_n red_a bag_n at_o the_o neck_n proboscis_n etc._n etc._n to_o grow_v as_o the_o time_n they_o be_v fit_a for_o or_o begin_v to_o tread_v for_o the_o relaxation_n cause_v by_o the_o pleasure_n of_o the_o semen_n make_v the_o party_n more_o capable_a of_o the_o nutriment_n thus_o it_o be_v that_o sleep_v cause_n the_o growth_n fatten_v and_o thrive_a of_o animal_n and_o red_a nose_n to_o grow_v so_o large_a by_o frequent_a relaxation_n upon_o the_o pleasure_n of_o wine_n ale_z etc._n etc._n as_o be_v say_v to_o which_o quantity_n distend_v the_o part_n may_v in_o the_o last_o mention_v case_n contribute_v i._o the_o form_n of_o opiate_n in_o this_o case_n may_v be_v either_o solid_a or_o liquid_a as_o you_o think_v â—it_a ii_o the_o dose_n must_v be_v proportion_v to_o the_o relaxation_n that_o you_o desire_v for_o more_o relax_n more_o and_o less_o less_o so_o must_v it_o be_v also_o proportion_v to_o the_o contraction_n that_o it_o be_v to_o take_v away_o therefore_o very_o grievous_a passion_n or_o sensation_n which_o cause_n proportionable_a contraction_n require_v great_a dose_n because_o their_o grievance_n and_o contraction_n do_v strong_o oppose_v the_o pleasure_n and_o relaxation_n that_o opiate_n cause_n therefore_o great_a pain_n as_o you_o will_v find_v in_o its_o due_a place_n require_v a_o extraordinary_a do_v iii_o the_o vehicle_n in_o contraction_n from_o grievous_a passion_n shall_v be_v wine_n or_o some_o comfortable_a cordial_n except_o they_o be_v the_o more_o turbulent_a passion_n as_o anger_n fury_n etc._n etc._n where_o composer_n as_o emulsion_n milk_n and_o water_n etc._n etc._n be_v best_a in_o all_o other_o case_n emollient_a and_o supply_a vehicles_n be_v most_o proper_a as_o soft_a smooth_a and_o slippery_a 〈◊〉_d broth_n etc._n etc._n iv_o the_o time_n to_o give_v they_o be_v at_o the_o due_a distance_n before_o bed_n time_n when_o the_o intention_n be_v consistent_a with_o sleep_n which_o itself_o be_v a_o great_a relaxer_n otherwise_o any_o time_n will_v serve_v as_o occasion_n or_o the_o intention_n of_o the_o physician_n require_v it_o v._o the_o regimen_n 1._o as_o to_o meat_n and_o drink_n be_v use_v moist_a emollient_a and_o lubricate_a thing_n as_o smooth_a broth_n somewhat_o â—at_a butter_v root_n herb_n sauce_n 〈◊〉_d milk-meat_n young_a flesh_n as_o of_o roast_a pig_n 〈◊〉_d lamb_n etc._n etc._n smooth_a drink_n as_o alc_n 〈◊〉_d etc._n etc._n 2._o as_o to_o sleep_v and_o wake_v that_o relax_n and_o this_o contract_n therefore_o that_o conduce_v this_o hinder_v 3._o as_o to_o rest_n and_o motion_n that_o relax_n and_o this_o contract_n 4._o as_o to_o the_o passion_n of_o the_o mind_n the_o pleasant_a as_o 〈◊〉_d joy_n pleasure_n comfort_n and_o all_o such_o do_v relax_v and_o the_o grievous_a as_o terror_n fear_v grief_n melancholy_n etc._n etc._n contract_n as_o pain_n do_v 5._o as_o to_o air_n the_o warm_a and_o moist_a or_o that_o when_o the_o quicksilver_n be_v low_a in_o the_o barometer_n or_o weatherglass_n do_v relax_v as_o do_v warm_a bath_n fomentation_n etc._n etc._n especial_o if_o emollient_a dry_v and_o cold_a air_n and_o that_o when_o the_o quicksilver_n be_v high_a do_v cause_n contraction_n 6._o as_o to_o excretion_n and_o retention_n general_o excretion_n do_v make_v room_n and_o way_n for_o thing_n to_o pass_v through_o or_o into_o the_o relaxed_a part_n as_o clyster_v for_o passage_n of_o the_o stone_n child_n reduction_n of_o hernias_fw-la etc._n etc._n but_o be_v sure_a not_o to_o make_v the_o excretion_n grievous_a because_o all_o grievous_a sensation_n cause_v contraction_n chap._n xxxiv_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o take_v away_o pain_n or_o grievous_a sensation_n this_o it_o do_v as_o be_v show_v by_o divert_v the_o sensitive_a soul_n and_o introduce_v a_o sense_n of_o pleasure_n which_o be_v contrary_a to_o grievous_a sensation_n or_o pain_n can_v be_v in_o the_o same_o subject_a with_o pain_n but_o chief_o and_o mechanical_o by_o relax_v all_o part_n and_o permit_v the_o springy_a animal_n spirit_n to_o expand_v and_o so_o become_v unfit_a to_o carry_v impression_n smart_o which_o be_v requisite_a to_o cause_v a_o sense_n of_o pain_n as_o have_v be_v prove_v therefore_o it_o be_v of_o most_o happy_a and_o glorious_a use_n in_o all_o pain_n but_o especial_o to_o be_v use_v 1._o in_o such_o as_o be_v not_o for_o any_o benefit_n to_o the_o person_n pain_v in_o order_n to_o alter_v or_o evacuate_v the_o grieve_v cause_n as_o in_o pocky_a scorbutical_a or_o hypochondriacal_a pain_n or_o such_o as_o proceed_v from_o any_o ill_a habit_n of_o body_n etc._n etc._n 2._o where_o pain_n hinder_v the_o take_v away_o of_o its_o cause_n or_o some_o benefit_n as_o when_o the_o pain_n of_o the_o stone_n do_v by_o contract_v the_o part_n hinder_v its_o own_o passage_n that_o of_o a_o tenesmus_n hinder_v go_v to_o stool_n that_o of_o the_o sphincter_n of_o the_o bladder_n hinder_v its_o open_n to_o let_v out_o urine_n clod_v blood_n phlegm_n matter_n or_o any_o such_o thing_n when_o that_o of_o the_o neck_n of_o the_o wâ—mb_n hinder_v delivery_n of_o a_o child_n afterbirth_n mole_n clod_v blood_n etc._n etc._n that_o of_o the_o mouth_n of_o the_o stomach_n hinder_v vomit_v when_o requisite_a or_o that_o of_o the_o pylorus_n hinder_v the_o detrusion_n of_o chyle_n or_o that_o of_o the_o intestine_n as_o by_o a_o inflammation_n etc._n etc._n stop_v the_o passage_n of_o the_o ordure_n and_o cause_v a_o iliack_a passion_n or_o that_o of_o the_o guilet_n hinder_v swollow_v of_o the_o larynx_n breathe_v or_o that_o of_o any_o part_n hinder_v perspiration_n or_o desire_a sweat_n or_o that_o of_o the_o venereal_a part_n stop_v the_o menses_fw-la or_o lochia_n etc._n etc._n in_o all_o which_o case_n it_o be_v and_o must_v in_o all_o reason_n be_v of_o excellent_a and_o if_o due_o manage_v of_o almost_o if_o not_o altogether_o infallible_a effect_n by_o take_v away_o the_o pain_n which_o cause_v the_o part_n to_o contract_v and_o make_v the_o stop_n etc._n etc._n 3._o where_o the_o cause_n of_o the_o pain_n can_v be_v remove_v but_o by_o perspiration_n sweat_v menses_fw-la lochia_n or_o urine_n â—s_n in_o pain_n in_o the_o habit_n of_o the_o body_n limb_n etc._n etc._n from_o cold_a wind_n or_o vapour_n gout_n rheumatism_n stitch_n pleurisy_n inflammation_n and_o many_o of_o the_o case_n aforemention_v it_o be_v excellent_a as_o it_o be_v 4._o where_o the_o pain_n irritation_n or_o grievous_a sensation_n cause_v nature_n to_o work_v irregular_o as_o in_o iliack_n â—_z hysterick_a fit_n fruitless_a convulsion_n canine_a apâ—_n etc._n etc._n in_o which_o case_n it_o excel_v all_o other_o mean_n for_o many_o reason_n 5._o where_o the_o pain_n be_v not_o likely_a to_o have_v a_o timely_a effect_n for_o good_a till_o people_n may_v be_v too_o much_o wear_v out_o 6._o in_o all_o pain_n that_o have_v not_o any_o material_a cause_n from_o the_o â—_z &c._n &c._n of_o the_o body_n as_o such_o as_o happen_v from_o passion_n wound_n prick_v of_o nerve_n tendon_n fracture_n dislocation_n amputation_n severe_a chirurgical_a operation_n etc._n etc._n 7._o in_o all_o pain_n from_o inflammation_n suppuration_n abseess_n tumour_n where_o repulsion_n be_v not_o convenient_a or_o possible_a 8._o in_o all_o pain_n that_o be_v more_o likely_a to_o cause_v fever_n than_o any_o
benefit_n as_o in_o many_o of_o the_o former_a to_o be_v short_a it_o be_v good_a and_o useful_a in_o all_o pain_n and_o grievous_a sensation_n 1._o eecept_n all_o such_o as_o tend_v to_o the_o speedy_a and_o timely_a benefit_n of_o person_n as_o those_o in_a woman_n labour_n grievance_n at_o stomach_n that_o cause_n vomit_v upon_o over-repletion_n or_o by_o reason_n of_o somewhat_o that_o grieve_v and_o be_v not_o convenient_a to_o stay_v at_o stomach_n or_o irritation_n to_o expectorate_v when_o much_o want_v as_o happen_v sometime_o in_o vomicas_fw-la pleurisy_n peripneumonias_n etc._n etc._n or_o such_o as_o irritate_fw-la and_o solicit_v to_o make_v water_n go_v to_o stool_n etc._n etc._n when_o evacuation_n of_o urine_n ordure_n ill_a humour_n etc._n etc._n be_v requisite_a 2._o except_o when_o grievous_a sensation_n be_v necessary_a call_n or_o intimation_n for_o supply_v refreshment_n etc._n etc._n as_o hunger_n thirst_v etc._n etc._n which_o shall_v be_v take_v off_o only_o by_o the_o pleasure_n of_o good_a meat_n and_o drink_v lest_o nature_n be_v defraud_v where_o you_o may_v observe_v a_o inconvenience_n that_o may_v happen_v by_o the_o frequent_a use_n of_o opium_n take_v away_o appetite_n without_o nutriment_n though_o this_o be_v much_o compensated_a by_o the_o relaxation_n and_o recruit_v that_o opiate_n give_v and_o their_o moderate_v the_o expense_n of_o spirit_n by_o take_v of_o contraction_n and_o may_v more_o if_o not_o whole_o by_o a_o regular_a and_o constant_a way_n of_o eat_v and_o drink_v temperate_o at_o usual_a time_n though_o the_o hunger_n may_v not_o by_o reason_n of_o the_o opiate_n be_v so_o great_a as_o at_o other_o time_n i._o the_o form_n be_v indifferent_a and_o to_o be_v order_v only_o according_a to_o the_o general_a rule_n remember_v that_o the_o liquid_a be_v best_a for_o speed_n ii_o the_o dose_n must_v be_v proportion_v to_o the_o pain_n or_o grievous_a sensation_n and_o always_o rather_o more_o than_o when_o there_o be_v no_o pain_n because_o its_o contraction_n oppose_v the_o relaxation_n to_o be_v induce_v by_o the_o opiate_n observe_v this_o method_n first_o give_v a_o good_a do_v then_o stay_v about_o 2_o or_o 3_o hour_n and_o if_o the_o pain_n be_v not_o at_o all_o lessen_v you_o may_v safe_o then_o give_v half_a the_o quantity_n again_o and_o afterward_o about_o a_o three_o part_n of_o the_o do_v every_o 2_o or_o 3_o hour_n till_o it_o begin_v to_o abate_v but_o upon_o the_o least_o sensible_a abatement_n you_o must_v forbear_v to_o give_v any_o more_o because_o that_o which_o do_v in_o some_o measure_n abate_v the_o pain_n do_v in_o the_o same_o proportion_n abate_v the_o contraction_n and_o consequent_o it_o have_v less_o to_o contest_v with_o therefore_o will_v be_v sure_a to_o conquer_v it_o for_o the_o same_o power_n that_o can_v subdue_v ten_o in_o some_o measure_n will_v subdue_v nine_o in_o a_o great_a measure_n and_o eight_o more_o easy_o than_o nine_o etc._n etc._n till_o the_o pain_n quite_o cease_v whereas_o if_o you_o add_v more_o power_n to_o the_o opiate_n it_o may_v be_v too_o much_o especial_o when_o the_o pain_n be_v thereby_o conquer_v and_o that_o it_o have_v no_o contraction_n to_o contest_v with_o for_o than_o it_o will_v be_v as_o if_o a_o great_a do_v be_v give_v to_o one_o that_o have_v no_o pain_n but_o if_o the_o pain_n increase_v again_o you_o may_v safe_o repeat_v the_o half_n do_v etc._n etc._n every_o 2_o or_o 3_o hour_n till_o it_o again_o begin_v to_o abate_v and_o no_o long_o which_o you_o have_v better_o observe_v to_o do_v as_o soon_o as_o ever_o the_o pain_n begin_v to_o return_v because_o it_o take_v some_o time_n to_o operate_v it_o sollow_v then_o that_o the_o liquid_a form_n be_v most_o convenient_a in_o this_o case_n for_o expedition_n my_o particular_a and_o effectual_a manner_n of_o use_v it_o in_o the_o gout_n will_v be_v somewhat_o too_o redious_a to_o be_v set_v down_o therefore_o since_o it_o may_v be_v obvious_a enough_o to_o the_o sagacious_a that_o consider_v what_o have_v be_v say_v and_o the_o nature_n of_o the_o distemper_n i_o will_v pass_v that_o by_o at_o this_o time_n iii_o the_o vehicle_n in_o cold_a stomach_n and_o constitution_n may_v be_v a_o glass_n of_o wine_n or_o some_o temperate_a cordial_n but_o in_o hot_a case_n or_o where_o a_o fever_n be_v fear_v emulsion_n milk_n and_o water_n or_o water_n alone_o or_o other_o acceptable_a cool_a thing_n or_o such_o as_o be_v direct_v in_o the_o case_n of_o procure_v relaxation_n in_o the_o last_o chapter_n because_o it_o be_v relaxation_n that_o take_v away_o pain_n as_o have_v be_v mechanical_o demonstrate_v but_o heâ—e_v there_o be_v no_o need_n of_o be_v scrupulous_a as_o to_o the_o vehicle_n unless_o it_o be_v in_o respect_n of_o heat_n and_o cold_a as_o the_o case_n happen_v iv_o the_o time_n may_v be_v any_o hour_n as_o the_o case_n require_v only_o remember_v that_o sleep_n conduce_v much_o to_o relaxation_n and_o therefore_o to_o the_o take_v away_o of_o pain_n v._o the_o regimen_n to_o be_v use_v in_o the_o case_n of_o relax_v in_o the_o last_o chapter_n will_v suffice_v but_o it_o be_v convenient_a as_o be_v say_v to_o regard_v the_o stomach_n and_o hot_a and_o cold_a constitution_n especial_o where_o there_o be_v any_o fear_n of_o fever_n by_o give_v cool_a liquid_n as_o emulsion_n etc._n etc._n and_o avoid_v hot_a or_o solid_a thing_n especial_o such_o as_o be_v hard_a of_o digestion_n as_o flâ—sh_v fish_n egg_n etc._n etc._n 1._o note_v that_o it_o be_v very_o advisable_v not_o to_o defer_v the_o use_n of_o opiate_n too_o long_o till_o people_n be_v very_o weak_a though_o it_o may_v seem_v that_o they_o will_v hinder_v some_o due_a evacuation_n for_o i_o can_v see_v what_o harm_n a_o refreshment_n by_o they_o may_v do_v any_o more_o than_o by_o sleep_n both_o depend_v upon_o the_o same_o cause_n viz._n relaxation_n it_o be_v true_a that_o by_o reason_n of_o sleep_n or_o a_o opiate_n the_o evacuation_n may_v be_v a_o little_a defer_v what_o then_o will_v any_o man_n deny_v sleep_n for_o that_o reason_n why_o then_o shall_v a_o physician_n deny_v a_o opiate_n to_o cause_v it_o respite_n nature_n and_o enable_v it_o to_o bear_v its_o burden_n or_o engage_v with_o difficulty_n the_o better_a 2._o remember_v always_o that_o sleep_n be_v a_o great_a help_n to_o take_v away_o pain_n and_o so_o be_v all_o thing_n that_o conduce_v to_o relaxation_n or_o pleasant_a diversion_n 3._o use_v means_n in_o pain_n of_o the_o hemorrhoid_v furdament_n or_o intestinum_fw-la rectum_fw-la and_o indeed_o in_o any_o pain_n within_o the_o gut_n unless_o it_o proceed_v from_o a_o looseness_n that_o opiate_n may_v not_o bind_v man_n too_o much_o as_o leâ—itives_n internal_o or_o emollient_a 〈◊〉_d or_o which_o of_o they_o may_v be_v most_o easy_o and_o convenient_o do_v and_o most_o to_o the_o purpose_n chap._n xxxv_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o cause_n sleep_n it_o primary_o cause_n sleep_v by_o relax_v and_o compose_v quiet_v soothe_v please_a and_o lull_v the_o sensitive_a soul_n and_o spirit_n it_o always_o relax_n but_o do_v not_o always_o sufficient_o compose_v or_o quiet_v the_o spirit_n to_o cause_n sleep_n to_o which_o both_o be_v requisite_a secundary_o by_o take_v away_o grievous_a passion_n or_o sensation_n when_o they_o happen_v to_o hinder_v it_o 1._o as_o soporiserous_a it_o be_v of_o incomparable_a use_n in_o all_o troublesome_a watch_n whether_o they_o be_v from_o grievous_a passion_n or_o sensation_n or_o irrequiete_a motion_n of_o the_o spirit_n though_o not_o so_o certain_a in_o this_o last_o case_n as_o in_o the_o former_a and_o therefore_o prove_v sometime_o unsuccessful_a in_o some_o person_n and_o in_o some_o sort_n of_o madness_n as_o the_o merry_a or_o furicus_n though_o it_o be_v effectual_a in_o melancholy_n and_o slow_a manias_fw-la as_o have_v be_v intimate_v for_o bare_a relaxation_n suffice_v in_o the_o two_o first_o case_n where_o sleep_n be_v hinder_v by_o contraction_n which_o it_o never_o fail_v to_o take_v off_o if_o give_v in_o a_o due_a quantity_n as_o have_v be_v direct_v 2._o to_o recruit_v the_o spirit_n as_o when_o people_n be_v tire_v with_o labour_n journey_n disease_n conflict_n of_o nature_n as_o by_o convulsion_n vomit_n purge_n hysteric_a fit_n and_o the_o like_a 3._o to_o relax_v compose_v take_v away_o pain_n moderate_a flux_n that_o depend_v upon_o grievous_a sensation_n or_o irritation_n and_o its_o consequent_a contraction_n or_o from_o motion_n or_o segregation_n of_o humour_n 4._o to_o promote_v flux_n that_o depend_v upon_o relaxation_n as_o perspiration_n sweat_v as_o also_o the_o menses_fw-la and_o lochia_n in_o some_o case_n of_o all_o which_o you_o have_v particular_a chapter_n which_o see_v i._o the_o form_n may_v be_v indifferent_o either_o solid_a or_o liquid_a as_o
it_o be_v best_o like_v and_o most_o suitable_a to_o people_n mind_n palate_n etc._n etc._n ii_o the_o do_v moderate_a except_o it_o be_v 1._o where_o some_o by_o accident_n require_v otherwise_o as_o pain_n looseness_n vomit_n and_o to_o titillate_v the_o venereal_a membrane_n because_o remote_a which_o see_v in_o the_o respective_a chapter_n of_o the_o use_n of_o opiate_n in_o those_o case_n 2._o where_o the_o general_a rule_n direct_v otherwise_o as_o in_o the_o soft_a flesh_a people_n child_n woman_n etc._n etc._n where_o the_o do_v must_v be_v less_o iii_o the_o vehicle_n must_v be_v the_o same_o as_o be_v direct_v to_o compose_v but_o in_o old_a people_n it_o be_v observe_v that_o smooth_a spirituous_a thing_n as_o good_a ale_n etc._n etc._n conduce_v very_o much_o to_o cause_v sleep_n because_o sulphur_n do_v qualifie-the_a volatile_a salt_n of_o the_o opium_n as_o be_v show_v iv_o the_o time_n in_o general_n be_v at_o the_o due_a distance_n before_o bedtime_n that_o be_v direct_v in_o the_o general_a rule_n but_o opiate_n may_v be_v give_v at_o any_o time_n when_o the_o case_n require_v as_o in_o the_o smallpox_n about_o 12_o 1_o or_o 2_o in_o the_o afternoon_n according_a as_o the_o â—tions_n which_o happen_v in_o the_o afternoon_n or_o towards_o the_o evening_n do_v seize_v they_o and_o in_o ague_n at_o the_o due_a distance_n before_o the_o paroxysm_n invade_v they_o 〈◊〉_d that_o the_o operation_n thereof_o may_v be_v fall_n and_o complete_a before_o the_o time_n that_o the_o fit_n be_v to_o begin_v and_o so_o in_o all_o other_o câ—ses_n of_o the_o like_a â—ind_n v._o the_o regimen_n in_o this_o 〈◊〉_d 〈◊〉_d 〈◊〉_d twosold_a aspect_n 1._o to_o promote_v 〈◊〉_d 2._o to_o compose_v and_o quiet_a motion_n 〈◊〉_d â—tions_n of_o the_o spirit_n 〈◊〉_d etc._n etc._n 〈◊〉_d 〈◊〉_d quiet_v be_v the_o two_o 〈◊〉_d 〈◊〉_d as_o to_o the_o first_o the_o regimen_n must_v be_v the_o same_o as_o be_v direct_v in_o the_o chapter_n of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o relax_v but_o as_o to_o compose_v and_o quiet_v the_o spirit_n i_o shall_v add_v somewhat_o though_o relaxer_n be_v general_o good_a for_o this_o purpose_n unless_o join_v with_o some_o agitate_v accident_n as_o heat_n or_o the_o like_a 1._o as_o to_o diet_n it_o shall_v consist_v of_o cool_a incrassate_a inviscate_a thing_n that_o be_v not_o aromatic_a acid_a or_o saline_a such_o be_v milk-meat_n emulsion_n almond_n milks_n chicken_n broth_n with_o cool_a herb_n water-gruel_n fresh_a and_o young_a soft_a flesh_n lettuce_n purstane_n spinage_n herb_n mercury_n mallow_n and_o such_o like_a mucilage_n as_o of_o quince_n fleabane_n etc._n etc._n the_o drink_n may_v be_v milk_n and_o water_n whey_n or_o such_o unfermented_a liquor_n or_o smooth_a small_a beer_n not_o too_o old_a for_o all_o stale_a drink_n be_v naught_o water_n where_o it_o agree_v etc._n etc._n 2._o rest_v of_o body_n and_o spirit_n must_v be_v contrive_v by_o all_o mean_n as_o by_o lean_v lie_a or_o sit_v still_o without_o any_o motion_n after_o it_o be_v take_v till_o bedtime_n and_o therefore_o let_v the_o person_n if_o the_o season_n permit_v be_v as_o much_o undress_v as_o may_v be_v in_o a_o loose_a garment_n or_o morning-gown_n all_o that_o time_n and_o be_v help_v off_o with_o his_o clothes_n that_o he_o may_v not_o agitate_v his_o body_n when_o sleepy_a and_o not_o before_o let_v he_o go_v into_o a_o cold_a bed_n in_o summer_n and_o but_o a_o little_a warm_v in_o winter_n and_o only_o have_v what_o bedclothe_n suffice_v and_o please_v he_o best_o and_o then_o lie_v absolute_o still_o without_o noise_n light_z or_o fire_n in_o the_o room_n 3._o rest_v and_o tranquillity_n of_o mind_n be_v very_o necessary_a which_o shall_v be_v not_o only_o free_a from_o grievous_a passion_n but_o from_o all_o excess_n of_o joyous_a one_o which_o too_o much_o agitate_v the_o spirit_n 4._o the_o air_n shall_v be_v moist_a and_o moderate_a and_o if_o not_o such_o by_o the_o wether_n render_v so_o by_o art_n especial_o in_o fever_n 5._o all_o evacuation_n shall_v be_v make_v that_o may_v any_o way_n disturb_v his_o sleep_n before_o he_o betake_v himself_o to_o it_o nor_o shall_v the_o stomach_n be_v over-full_a or_o empty_a lest_o any_o grievance_n may_v be_v thereby_o create_v 6._o emollient_a tepid_a bath_n fomentation_n feetwash_n etc._n etc._n do_v fine_o dispose_v people_n to_o sleep_n but_o take_v care_n they_o be_v not_o too_o hot_a for_o heat_n cause_v a_o stir_n of_o blood_n and_o spirit_n which_o be_v a_o enemy_n to_o sleep_n 1._o note_v that_o long_o sleep_v after_o great_a fatigue_n or_o long_o watch_v ought_v not_o to_o be_v very_o frightful_a if_o the_o do_v be_v moderate_a and_o that_o the_o person_n take_v sustenance_n 2._o note_v that_o old_a or_o dry_a person_n or_o such_o as_o be_v very_o unapt_a to_o sleep_v after_o opiate_n be_v often_o cause_v to_o sleep_v by_o smooth_a wine_n ale_z cowslip_n wine_n or_o the_o like_a because_o the_o gentle_a oiliness_n of_o such_o liquor_n do_v correct_v the_o acrimony_n of_o their_o volatile_a salt_n and_o at_o the_o same_o time_n cause_n a_o sense_n of_o pleasure_n which_o relax_n and_o cause_n sleep_v it_o have_v be_v observe_v that_o even_o ambergrise_v and_o musk_n which_o exagitate_v the_o blood_n and_o spirit_n cause_v old_a man_n to_o sleep_n which_o happen_v by_o their_o fine_a sulphur_n ready_o fasten_v upon_o the_o acrimonious_a volatile_a salt_n as_o spirit_n of_o wine_n do_v upon_o sal_fw-la ammoniac_a which_o be_v mix_v do_v soon_o coagulate_v therefore_o i_o be_o apt_a to_o think_v that_o camphire_n will_v be_v of_o excellent_a use_n to_o correct_v the_o opium_n and_o the_o volatile_a salt_n of_o the_o body_n in_o such_o case_n because_o it_o be_v experimental_o certain_a that_o it_o correct_v the_o acrimony_n of_o urine_n of_o semen_n virile_a cantharides_n etc._n etc._n 3._o note_v that_o the_o dry_a the_o body_n be_v the_o more_o unapt_a be_v opiate_n to_o cause_n sleep_n therefore_o dry_a body_n as_o of_o old_a man_n hectical_a person_n etc._n etc._n shall_v be_v well_o moisten_v by_o incrassative_a moistener_n as_o emulsion_n and_o such_o thing_n as_o be_v above_o mention_v and_o order_v in_o the_o chapter_n of_o the_o relax_a use_n of_o opiate_n from_o what_o be_v say_v i_o do_v conclude_v that_o opiate_n do_v cause_n sleep_v very_o ready_o where_o the_o oily_a part_n abound_v and_o that_o thing_n that_o have_v a_o fine_a oleous_a sulphur_n be_v very_o good_a corrector_n of_o it_o where_o acrimonious_a volatile_a salt_n abound_v in_o order_n to_o cause_n sleep_n and_o that_o hence_o it_o be_v that_o some_o ancient_a people_n will_v often_o sleep_v better_o by_o the_o use_n of_o the_o aforementioned_a smooth_a ferment_v sulphureous_a liquor_n than_o by_o the_o use_n of_o opium_n from_o all_o which_o it_o appear_v that_o sleep_n be_v not_o such_o a_o property_n of_o opium_n as_o people_n make_v it_o to_o be_v because_o that_o beside_o relax_v sleep_v also_o require_v a_o great_a rest_n of_o the_o spirit_n and_o the_o sensitive_a soul_n it_o seem_v very_o probable_a from_o the_o premise_n that_o anodyne_n sulphur_n of_o vitriol_n will_v be_v excellent_a to_o cause_v old_a man_n to_o sleep_n for_o it_o doubtless_o cause_n sleep_v only_o by_o obtund_v and_o qualify_a our_o volatile_a salt_n as_o white_a 〈◊〉_d and_o other_o balsamicks_n will_v often_o do_v chap._n xxxvi_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o stop_v flux_n it_o palliate_v moderate_v and_o stop_v flux_n 1._o by_o take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o cause_n contraction_n to_o squeeze_v they_o out_o and_o promote_v their_o motion_n 2._o because_o it_o compose_v and_o still_v the_o motion_n of_o humour_n by_o the_o relaxation_n and_o the_o sleep_n that_o it_o cause_n which_o quiet_v motion_n 3._o because_o thereby_o and_o by_o its_o combine_a agreeableness_n and_o texture_n it_o congregate_n the_o disgregated_a humour_n 4._o because_o the_o relaxation_n suspend_v the_o humour_n 5._o because_o it_o discuss_n ill_a humour_n 6._o because_o the_o pore_n be_v open_v by_o the_o relaxation_n the_o humour_n that_o cause_v the_o flux_n be_v gradual_o perspire_v by_o that_o most_o natural_a and_o universal_a sort_n of_o evacuation_n for_o it_o be_v plain_a reason_n and_o common_a observation_n that_o a_o plentiful_a evacuation_n at_o pore_n stop_v flux_n per_fw-la anum_fw-la etc._n etc._n and_o if_o it_o continue_v perfect_o cure_v they_o ☞_o hence_o it_o be_v that_o the_o use_v of_o opiate_n continue_v do_v happy_o not_o only_o palliate_v but_o perfect_o cure_v diarrheas_n dysentery_n defluxion_n catarrh_n etc._n etc._n it_o therefore_o follow_v that_o it_o be_v of_o great_a use_n 1._o to_o palliate_v moderate_a or_o cure_v all_o flux_n that_o proceed_v from_o irritation_n of_o humour_n as_o vomit_n
nothing_o more_o sure_a than_o that_o it_o have_v such_o a_o effect_n if_o the_o do_v be_v large_a enough_o and_o that_o most_o of_o the_o eastern_a nation_n use_v it_o for_o that_o end_n with_o infallible_a effect_n iii_o the_o time_n shall_v be_v 5_o or_o 6_o hour_n before_o the_o effect_n be_v expect_v or_o at_o bedtime_n to_o cause_v its_o effect_n towards_o the_o morning_n particular_o in_o the_o case_n of_o exciting_a to_o venery_n iv_o the_o regimen_n as_o to_o diet_n it_o must_v be_v nourish_v warm_a comfort_a and_o titillate_v with_o realish_v and_o high_a sauce_n oyster_n anchovy_n caviar_n cockle_n ketchup_o mango_n garlic_n onion_n leek_n bear_v garlic_n rocket_n sives_z shelot_n ginger_n aromatics_n roâ—ts_n of_o satyrion_n feaverfew_n goatsbeard_n silver-weed_n skirret_n parsnip_n and_o artichoke_n the_o use_n of_o ambergrise_n musk_n and_o civet_n be_v commend_v but_o good_a stomach-wine_n and_o thâ—_n like_a be_v certain_o of_o use_n sine_fw-la baccho_fw-la friget_fw-la venus_n but_o it_o be_v certain_a that_o camphire_n and_o sulphureous_a thing_n unferment_v as_o oil_n rosin_n and_o fat_a thing_n oppose_v titillation_n as_o do_v also_o slimy_a mucilaginous_a and_o cool_a thing_n chap._n thirty-nine_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o cause_n watch_v i_o have_v show_v how_o opiate_n cause_v watch_v in_o some_o person_n by_o reason_n of_o the_o over-agitating_a and_o actuate_a the_o spirit_n and_o titillate_v by_o its_o volatile_a salt_n yet_o do_v they_o by_o cause_v pleasure_n and_o relaxation_n support_v the_o spirit_n while_o the_o extraordinary_a ovation_n of_o they_o hinder_v sleep_n therefore_o it_o be_v of_o use_n to_o such_o as_o it_o cause_v watch_v to_o when_o it_o be_v requisite_a for_o they_o to_o watch_v about_o any_o business_n labour_n journey_n etc._n etc._n i._o the_o form_n may_v be_v either_o solid_a or_o liquid_a ii_o the_o do_v moderate_a iii_o the_o vehicle_n shall_v be_v acid_n or_o other_o liquid_n with_o volatile_a salt_n iv_o the_o time_n may_v be_v at_o any_o hour_n when_o want_v v._o the_o regimen_n quite_o contrary_a to_o that_o of_o sleep_n and_o relaxation_n viz._n to_o use_v voluntary_a motion_n etc._n etc._n chap._n xl._n of_o the_o alterative_a use_n of_o the_o panacea_fw-la of_o opium_n you_o see_v the_o mighty_a extent_n and_o general_n use_v of_o the_o panacea_fw-la of_o opium_n as_o a_o pleaser_n of_o sensation_n which_o take_v up_o the_o nine_o last_o chapter_n to_o mention_v the_o head_n of_o its_o performance_n without_o descend_v into_o all_o particular_n because_o their_o number_n be_v indefinite_a how_o universal_a then_o must_v its_o use_n be_v when_o we_o add_v thereto_o its_o effect_n as_o a_o consummate_a alterative_a which_o 1._o invigorates_n nature_n by_o comfort_v the_o sublimest_n principles_n thereof_o viz._n the_o sensitive_a soul_n and_o spirit_n that_o be_v the_o original_a of_o all_o motion_n and_o action_n 2._o furnish_v they_o with_o a_o indefatigable_a euphory_n in_o the_o great_a business_n of_o our_o preservation_n 3._o put_v the_o best_a mean_n into_o the_o hand_n of_o invigorated_a nature_n for_o that_o end_n that_o be_v most_o agreeable_a principle_n even_o more_o powerful_a and_o of_o a_o great_a energy_n than_o our_o own_o which_o must_v as_o agreeable_a and_o exalt_a menstruum_n do_v resolve_v all_o humour_n congregate_a the_o good_a and_o homogeneous_a and_o separate_v the_o effete_a and_o heterogeneous_a part_n which_o it_o 4._o discuss_n and_o dissipate_v by_o its_o brisk_a and_o active_a volatile_a salt_n and_o at_o last_o 5._o convey_v out_o of_o the_o body_n by_o a_o liberal_a perspiration_n the_o most_o natural_a universal_a and_o copious_a way_n of_o evacuation_n all_o which_o be_v consider_v it_o be_v i_o think_v manifest_a that_o it_o must_v excel_v all_o other_o panaceas_fw-la 1._o because_o it_o take_v away_o the_o grievance_n or_o form_n of_o disease_n upon_o the_o very_a first_o administration_n thereof_o whereas_o other_o medicament_n do_v that_o but_o gradual_o as_o they_o alter_v or_o subdue_v the_o matter_n 2._o because_o it_o high_o comfort_v nature_n or_o the_o sensitive_a soul_n and_o spirit_n from_o the_o very_a commencement_n of_o the_o cure_n and_o through_o the_o whole_a process_n thereof_o if_o due_o repeat_v which_o other_o medicament_n do_v only_o by_o insensible_a degree_n as_o they_o gain_v upon_o the_o disease_n 3._o because_o it_o procure_v sleep_n the_o sweet_a and_o chief_a refreshment_n of_o and_o first_o cure_n in_o nature_n so_o that_o i_o can_v see_v what_o can_v be_v desire_v in_o a_o medicament_n that_o it_o be_v not_o accomplish_v with_o whereas_o other_o panaceas_fw-la be_v deficient_a or_o at_o least_o come_v very_o short_a of_o we_o in_o these_o extraordinary_a qualification_n which_o seem_v to_o make_v it_o absolute_o complete_a and_o consummate_a 4._o because_o it_o from_o the_o very_a first_o compose_v all_o perturbation_n and_o enormous_a motion_n of_o the_o sensitive_a soul_n or_o â—_z which_o helmont_n attribute_n to_o the_o archaeus_n place_v all_o disease_n therein_o and_o therefore_o say_v ort._n imag._n mâ—rb_n sect._n 12._o universal_a quoddam_fw-la arcanum_fw-la consopotivum_fw-la &_o sedativum_fw-la archaei_n est_fw-la adhibendum_fw-la that_o be_v a_o universal_a remedy_n that_o appease_v the_o archaeus_n shall_v be_v use_v and_o what_o appease_v or_o compose_v it_o more_o than_o or_o as_o much_o as_o opiate_n therefore_o i_o can_v wonder_v that_o paracelsus_n shall_v declare_v that_o it_o serve_v his_o purpose_n when_o all_o his_o arcanas_fw-la sail_v or_o that_o helmont_n shall_v be_v in_o a_o rapture_n upon_o the_o apprehension_n of_o the_o excellency_n of_o opium_n if_o the_o noxious_a quality_n be_v separate_v from_o it_o though_o he_o have_v a_o very_a wrong_a notion_n of_o its_o operation_n as_o appear_v potest_fw-la medicam_fw-la sect._n 4._o where_o he_o say_v that_o opium_n archaeum_n abigit_fw-la &_o fugat_fw-la that_o be_v opium_n chase_v and_o put_v the_o archaeus_n to_o flight_n which_o on_o the_o contrary_a it_o high_o please_v and_o comfort_n it_o be_v endless_a and_o a_o kind_a of_o impertinence_n to_o descend_v into_o particular_n in_o the_o use_n of_o a_o panacea_fw-la therefore_o have_v show_v how_o it_o operate_v by_o invigorate_n nature_n cause_v euphory_n ease_n sleep_v resolve_v all_o humour_n as_o a_o general_a menstruum_fw-la or_o alkahe_a congregate_a the_o good_a separate_a discuss_v and_o carry_v off_o the_o bad_a particle_n etc._n etc._n it_o remain_v only_o that_o i_o show_v you_o how_o to_o use_v it_o as_o to_o form_n do_v etc._n etc._n leave_v the_o administration_n thereof_o in_o particular_a case_n to_o physician_n therein_o concern_v i._o the_o form_n that_o i_o main_o approve_v of_o to_o alter_v be_v the_o liquid_a because_o the_o solid_a be_v in_o some_o measure_n though_o not_o much_o impair_v by_o the_o evaporation_n to_o the_o due_a consistence_n and_o do_v not_o consist_v of_o the_o fine_a part_n as_o the_o liquid_a do_v ii_o the_o dose_n may_v be_v at_o first_o about_o 20_o drop_n add_v a_o drop_n to_o every_o do_v till_o the_o distemper_n be_v in_o good_a measure_n abate_v then_o let_v the_o same_o number_n of_o drop_n be_v continue_v till_o the_o person_n be_v well_o and_o afterward_o abate_v by_o a_o drop_v every_o day_n till_o you_o come_v to_o ten_o or_o less_o or_o to_o such_o a_o inconsiderable_a do_v that_o you_o can_v find_v no_o effect_n at_o all_o note_v that_o though_o i_o be_o cautious_a in_o the_o dose_v till_o trusty_a experience_n give_v more_o assurance_n yet_o do_v i_o believe_v that_o no_o inconvenience_n will_v be_v find_v by_o far_o great_a dose_n if_o by_o any_o unless_o very_o excessive_a as_o 1_o or_o 2_o gallon_n of_o wine_n be_v in_o respéct_n of_o a_o pint_n which_o in_o such_o dose_n may_v be_v and_o be_v injurious_a such_o as_o have_v pain_n to_o be_v take_v off_o must_v use_v it_o as_o be_v direct_v in_o the_o chapter_n of_o its_o use_n to_o take_v away_o pain_n gradual_o increase_a so_o as_o to_o keep_v it_o off_o and_o when_o the_o cure_n be_v in_o great_a measure_n perform_v must_v continue_v and_o decrease_v as_o be_v aforesaid_a the_o like_a be_v to_o be_v say_v as_o to_o flux_n etc._n etc._n iii_o the_o vehicle_n may_v be_v in_o general_a plain_a water_n or_o rather_o alter_v and_o make_v bitter_a by_o a_o infusion_n of_o the_o ingredient_n of_o the_o bitter_a decoction_n or_o agrimony_n wood-sage_a bean_n trefoil_n or_o the_o like_a good_a bitter_a thing_n that_o be_v know_v by_o experience_n to_o cause_v a_o good_a digestion_n in_o particular_a case_n the_o vehicle_n may_v be_v appropriate_v to_o the_o disease_n yet_o always_o so_o order_v it_o that_o it_o may_v be_v stomachical_a iv_o the_o time_n shall_v general_o be_v in_o the_o morning_n unless_o sleep_v at_o night_n be_v to_o be_v procure_v thereby_o if_o so_o you_o must_v order_v thing_n as_o in_o the_o
and_o motion_n fail_v together_o of_o the_o great_a perspiration_n and_o all_o other_o effect_n of_o relaxation_n in_o such_o syncopes_fw-la or_o leipothymy_n in_o a_o yet_o high_o degree_n than_o in_o sleep_n wherein_o the_o sensitive_a soul_n do_v not_o quite_o let_v go_v the_o reign_v of_o contraction_n as_o appear_v by_o the_o motion_n that_o remain_v as_o of_o the_o heart_n intestine_n etc._n etc._n though_o far_o more_o remiss_a in_o sleep_n than_o in_o a_o wake_v state_n note_v that_o such_o leipothymy_n be_v as_o be_v hint_v of_o the_o same_o nature_n as_o sleep_n be_v but_o that_o they_o be_v sudden_a more_o profound_a and_o not_o so_o usual_a natural_a and_o of_o course_n as_o sleep_n be_v which_o make_v they_o more_o amaze_a and_o surprise_v therefore_o it_o follow_v that_o they_o be_v as_o sleep_n be_v a_o mean_n of_o recruit_v when_o all_o work_n and_o tug_v by_o defensive_a contraction_n fail_v and_o so_o the_o last_o refuge_n of_o the_o sensitive_a soul_n when_o overtired_n in_o order_n to_o recover_v strength_n for_o a_o fresh_a engagement_n with_o the_o enemy_n as_o be_v tire_v at_o night_n the_o sensitive_a soul_n loosen_v the_o rign_n of_o contraction_n to_o enable_v he_o the_o better_a to_o fall_v to_o his_o work_n the_o next_o day_n this_o you_o will_v find_v by_o all_o reason_n and_o experience_n to_o be_v the_o true_a state_n of_o leipothymy_n upon_o grievance_n and_o fatigue_n though_o not_o hitherto_o mind_v that_o i_o know_v of_o many_o true_a and_o useful_a consequence_n do_v hence_o follow_v as_o that_o we_o be_v not_o always_o to_o disturb_v they_o or_o put_v they_o out_o of_o these_o recruit_v leipothymy_n by_o grievous_a mean_n as_o pricking_n pinch_n etc._n etc._n but_o only_o by_o cordial_n and_o refresh_a thing_n as_o you_o will_v treat_v a_o person_n much_o tire_v or_o by_o let_v they_o take_v their_o nap_n if_o i_o may_v so_o call_v it_o if_o there_o be_v not_o very_o eminent_a danger_n but_o it_o be_v endless_a and_o beside_o my_o purpose_n to_o make_v a_o particular_a discourse_n of_o this_o matter_n which_o will_v belong_v more_o proper_o to_o my_o tract_n of_o animal_n mechanism_n 14._o death_n happen_v sometime_o though_o very_o rare_o and_o that_o in_o very_o weak_a people_n that_o take_v little_a or_o no_o sustenance_n because_o either_o when_o fall_v into_o such_o syncopes_fw-la they_o never_o come_v out_o of_o they_o by_o reason_n that_o they_o have_v not_o within_o they_o wherewith_o to_o recruit_v their_o spirit_n or_o that_o opium_n take_v they_o much_o spend_v and_o tire_v with_o distemper_n cause_n as_o in_o weak_a and_o weary_a people_n a_o most_o profound_a sopor_fw-la which_o not_o recruit_v they_o who_o take_v or_o digest_v no_o sustenance_n they_o must_v rather_o grow_v weak_a and_o weak_a for_o somewhat_o be_v spend_v while_o we_o live_v and_o consequent_o the_o sleep_n or_o sopor_fw-la more_o and_o more_o profound_a till_o they_o sleep_v their_o last_o for_o want_v of_o some_o recruit_v which_o be_v the_o very_a thing_n that_o natural_o lessen_v sleep_n and_o awake_v we_o when_o there_o be_v no_o other_o apparent_a cause_n for_o as_o the_o be_v tire_v and_o want_v of_o recruit_v cause_n sleep_v so_o the_o have_v it_o cause_v wake_v or_o which_o be_v the_o same_o in_o effect_n no_o far_o need_v of_o relaxation_n for_o recruit_n sake_n so_o that_o the_o sensitive_a soul_n fall_v to_o his_o useful_a work_n of_o vigilative_a contraction_n for_o sense_n and_o motion_n sake_n 15._o it_o sometime_o cause_n purge_v which_o happen_v as_o far_o as_o i_o have_v observe_v or_o can_v learn_v only_o when_o it_o be_v give_v in_o a_o good_a quantity_n to_o person_n of_o a_o strong_a digestion_n or_o canine_a appetite_n the_o case_n be_v thus_o when_o person_n that_o be_v of_o a_o strong_a digestion_n take_v a_o resinous_n opiate_n in_o good_a quantity_n they_o do_v in_o great_a measure_n by_o their_o fix_a salt_n at_o stomach_n and_o strong_a digestion_n subdue_v the_o volatility_n of_o the_o opium_n and_o dissolve_v its_o rosin_n which_o then_o as_o acrimonious_a rosin_n or_o vomit_n subdue_v by_o fix_a salt_n use_v to_o do_v cause_v purge_v hence_o it_o be_v that_o it_o general_o if_o not_o always_o purge_v dog_n and_o people_n of_o a_o high_a canine_a appetite_n and_o that_o sometime_o meet_v such_o fix_a salt_n it_o purge_v the_o consumptive_a bartholine_n say_v that_o mandrake_n juice_n purge_v when_o it_o meet_v with_o acrimonious_a fix_a salt_n erastus_n and_o quercelan_n do_v agree_v that_o it_o have_v a_o purgative_n quality_n but_o that_o it_o do_v not_o always_o exert_v it_o 1._o because_o it_o take_v away_o the_o sense_n of_o irritation_n 2._o because_o it_o be_v give_v in_o too_o small_a a_o quantity_n the_o reason_n be_v just_a and_o right_a and_o not_o only_o consistent_a with_o but_o confirm_v what_o i_o say_v note_v that_o this_o be_v not_o intend_v of_o the_o purge_v that_o happen_v after_o the_o declination_n of_o its_o operation_n which_o be_v as_o you_o will_v find_v from_o another_o cause_n therefore_o this_o do_v not_o smell_v of_o the_o opium_n as_o the_o other_o do_v because_o it_o be_v past_a and_o go_v before_o that_o in_o the_o declination_n happen_v of_o which_o more_o in_o its_o proper_a place_n 16._o it_o raise_v and_o revive_v some_o person_n that_o be_v almost_o expire_a in_o two_o case_n one_o be_v when_o such_o as_o have_v be_v use_v to_o take_v it_o be_v even_o expire_a for_o want_n of_o it_o of_o which_o more_o hereafter_o the_o other_o case_n be_v when_o violent_a contraction_n as_o from_o pain_n cold_a vomit_n and_o grievous_a passion_n as_o terror_n etc._n etc._n be_v the_o cause_n that_o people_n be_v almost_o expire_a for_o it_o take_v off_o the_o contraction_n by_o relax_v etc._n etc._n 17._o it_o stay_v very_o long_o at_o stomach_n when_o the_o rosin_n thereof_o stick_v to_o the_o stomach_n and_o be_v there_o detain_v beside_o that_o the_o stomach_n be_v relax_v and_o have_v little_a sense_n or_o motion_n as_o in_o sleep_n do_v not_o soon_o digest_v it_o or_o discharge_v it_o it_o be_v fine_a in_o this_o case_n and_o all_o other_o to_o observe_v how_o sensation_n and_o motion_n go_v hand_n in_o hand_n keep_v equal_a pace_n and_o equal_a proportion_n as_o it_o plain_o must_v be_v by_o the_o principle_n of_o relaxation_n and_o contraction_n which_o i_o have_v state_v and_o prove_v 18._o it_o cause_v stoppage_n of_o urine_n sometime_o especial_o in_o old_a people_n by_o over_o relax_v and_o cause_v a_o kind_n of_o a_o temporary_a palsy_n of_o the_o bladder_n as_o be_v show_v and_o take_v away_o the_o sense_n of_o the_o irritation_n of_o the_o urine_n which_o shall_v contract_v the_o bladder_n to_o squeeze_v it_o out_o by_o which_o mean_v it_o happen_v sometime_o that_o the_o bladder_n come_v to_o be_v so_o over_o extend_v beyond_o its_o due_a tone_n that_o they_o can_v contract_v it_o to_o make_v water_n in_o all_o which_o case_n strong_a contracter_n as_o cold_a terror_n etc._n etc._n immediate_o cure_v they_o the_o very_a put_v the_o scrotum_fw-la to_o the_o edge_n of_o a_o cold_a chamberpot_n have_v effect_v it_o several_a time_n by_o my_o advice_n though_o if_o need_v be_v you_o must_v come_v to_o dash_v of_o cold_a water_n upon_o the_o region_n of_o the_o bladder_n or_o pump_v on_o it_o or_o dip_v in_o it_o etc._n etc._n so_o terror_n and_o cause_v a_o very_a smart_n pain_n especial_o near_o those_o part_n will_v do_v much_o but_o cold_a be_v the_o ready_a and_o best_a remedy_n 19_o it_o sometime_o prove_v dangerous_a after_o great_a hemorrbage_n or_o evacuation_n as_o tapping_n in_o dropsy_n etc._n etc._n because_o the_o relaxation_n hinder_v the_o part_n due_o to_o contract_v upon_o what_o remain_v which_o may_v cause_v great_a mischief_n as_o discontinuation_n of_o motion_n etc._n etc._n thus_o have_v you_o all_o the_o constant_a frequent_a and_o rare_a effect_n of_o opium_n take_v internal_o in_o a_o moderate_a do_v so_o natural_o easy_o plain_o and_o mechanical_o explicate_v that_o people_n may_v in_o my_o judgement_n more_o admire_v how_o all_o fail_v of_o discover_v the_o manner_n of_o their_o production_n than_o that_o i_o find_v it_o as_o man_n be_v apt_a to_o think_v of_o the_o circulation_n of_o the_o blood_n which_o now_o as_o i_o hope_v the_o effect_n of_o opium_n do_v seem_v very_o obvious_a both_o which_o case_n be_v to_o i_o very_o strong_a argument_n of_o a_o be_v that_o rule_n and_o dispose_n darken_v and_o illuminate_v etc._n etc._n as_o he_o please_v when_o i_o consider_v that_o both_o the_o circulation_n of_o the_o blood_n and_o the_o cause_n of_o the_o operation_n of_o opium_n viz._n pleasure_n at_o stomach_n etc._n etc._n fall_v under_o the_o sense_n of_o many_o million_o who_o in_o one_o case_n see_v the_o blood_n move_v and_o in_o the_o other_o feel_v