a_o very_o long_o and_o lavish_a use_n thereof_o the_o inconvenience_n of_o leave_v off_o the_o use_n of_o opium_n do_v bear_v a_o certain_a proportion_n to_o the_o time_n and_o quantity_n that_o it_o have_v be_v use_v in_o 1._o note_v that_o the_o turk_n do_v drink_v some_o water_n always_o after_o the_o take_n of_o opium_n as_o be_v the_o best_a menstruum_fw-la to_o dissolve_v it_o 2._o note_v that_o it_o be_v usual_a with_o they_o to_o take_v a_o drachm_n in_o the_o morning_n and_o so_o much_o in_o the_o afternoon_n and_o so_o may_v we_o as_o well_o as_o they_o if_o use_v to_o it_o and_o it_o be_v a_o very_a silly_a say_n that_o you_o will_v find_v in_o author_n that_o they_o be_v better_a able_a to_o bear_v it_o because_o of_o the_o climate_n etc._n etc._n whereas_o the_o more_o northern_a person_n be_v better_a able_a to_o take_v it_o than_o the_o southern_a as_o will_v hereafter_o appear_v most_o plain_o i_o be_o tell_v of_o one_o near_o banbury_n that_o take_v two_o ounce_n a_o day_n 3._o note_v that_o among_o the_o effect_n of_o opium_n may_v be_v observe_v many_o seem_a contradiction_n yet_o be_v there_o nothing_o more_o certain_a than_o the_o several_a different_a matter_n of_o fact_n which_o no_o doubt_n have_v be_v a_o great_a cause_n to_o puzzle_v the_o world_n about_o it_o and_o to_o run_v man_n into_o strange_a absurdity_n concern_v its_o operation_n and_o all_o to_o deviate_v so_o far_o from_o the_o truth_n that_o nothing_o in_o nature_n can_v be_v far_o unless_o you_o will_v say_v that_o heat_n cool_v or_o what_o please_v the_o sensitive_a soul_n be_v at_o the_o same_o time_n abhor_v by_o it_o now_o because_o these_o seem_a contradiction_n in_o the_o effect_n of_o opium_n be_v the_o great_a rub_n to_o be_v meet_v with_o and_o that_o the_o reader_n may_v take_v the_o better_a estimate_n of_o the_o undertake_n and_o my_o explication_n of_o its_o effect_n when_o i_o come_v to_o it_o i_o shall_v not_o fear_v to_o enumerate_v they_o distinct_o though_o they_o will_v make_v the_o strange_a catalogue_n of_o riddle_n that_o ever_o be_v see_v trust_v in_o he_o that_o create_v this_o wonderful_a medicament_n that_o he_o will_v enable_v i_o to_o explain_v all_o its_o effect_n the_o seem_a contradiction_n in_o the_o effect_n of_o opium_n 1._o it_o cause_v sleep_v and_o watch_v 2._o it_o cause_n and_o prevent_v sweat_n 3._o it_o relax_n and_o stop_v looseness_n 4._o it_o stop_v flux_n and_o cause_n that_o of_o sweat_n etc._n etc._n 5._o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v by_o that_o sense_n to_o venery_n 6._o it_o cause_v stupidity_n and_o promptitude_n in_o business_n cloudiness_n and_o serenity_n of_o mind_n 7._o it_o excite_v the_o spirit_n and_o quiet_v they_o 8._o it_o be_v very_o hot_a yet_o cool_v in_o fever_n 9_o it_o be_v hot_a and_o bitter_a yet_o lessen_v appetite_n even_o in_o cold_a stomach_n 10._o it_o stop_v and_o promote_v urine_n 11._o it_o relax_n and_o weaken_v yet_o enable_v we_o to_o undergo_v labour_n journey_n etc._n etc._n 12._o it_o cause_n and_o prevent_v abortion_n 13._o it_o stop_v vomit_v above_o all_o thing_n yet_o cause_n most_o violent_a tedious_a and_o dangerous_a vomit_n 14._o it_o stop_v purge_v in_o a_o most_o eminent_a manner_n yet_o sometime_o cause_v it_o 15._o it_o be_v very_o acrimonious_a yet_o as_o all_o say_v obtund_v acrimony_n however_o it_o allay_v pain_n proceed_v from_o acrimony_n 16._o it_o cause_v a_o furious_a madness_n yet_o compose_v the_o spirit_n above_o all_o thing_n 17._o it_o cause_v 〈◊〉_d yet_o sometime_o cure_v they_o as_o willis_n say_v 18._o it_o cause_v palsy_n yet_o have_v i_o know_v it_o to_o cure_v a_o palsy_n 19_o it_o cause_v dryness_n in_o the_o mouth_n yet_o take_v off_o thirst_n in_o fever_n 20._o it_o cure_v and_o cause_v a_o hiccough_n 21._o it_o stanche_n blood_n yet_o cause_v the_o blood_n to_o come_v outward_a as_o appear_v by_o the_o efflorescence_n or_o redness_n of_o the_o skin_n that_o it_o cause_n yet_o move_v the_o menses_fw-la and_o lochia_n 22._o we_o have_v many_o instance_n of_o it_o promote_a and_o hinder_v critical_a motion_n 23._o it_o raise_v very_o weak_a people_n when_o nothing_o beside_o will_v do_v it_o yet_o it_o kill_v other_o weak_a people_n 24._o it_o cause_n and_o cure_n convulsion_n 25._o it_o cause_v relaxation_n and_o contraction_n of_o the_o same_o part_n 26._o it_o relax_n yet_o cause_v rigidity_n tension_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n thus_o have_v i_o fair_o and_o faithful_o lay_v the_o whole_a onus_fw-la of_o the_o operation_n effect_n and_o contradictory_n phenomena_n of_o opium_n upon_o my_o shoulder_n however_o i_o come_v off_o and_o clear_v myself_o of_o the_o intricacy_n maze_n and_o cross_a effect_n thereof_o by_o explain_v they_o which_o none_o upon_o the_o view_n thereof_o will_v think_v possible_a and_o none_o before_o i_o dare_v as_o much_o as_o enumerate_v for_o that_o end_n chap._n vii_o the_o author_n contrive_v a_o compendious_a way_n of_o examine_v all_o opinion_n concern_v the_o operation_n of_o opium_n have_v without_o any_o sly_a or_o sordid_a evasion_n or_o considerable_a omission_n which_o have_v be_v the_o perfidious_a course_n of_o author_n in_o this_o case_n full_o and_o true_o enumerate_v the_o sensible_a and_o certain_a effect_n of_o opium_n in_o humane_a body_n and_o thereby_o empanneled_a a_o just_a jury_n for_o the_o trial_n of_o hypothesise_n which_o must_v be_v judge_v by_o the_o effect_n or_o phenomena_n of_o opium_n i_o will_v now_o proceed_v to_o their_o examination_n but_o because_o it_o will_v be_v endless_a to_o take_v every_o one_o particular_o into_o consideration_n i_o will_v use_v their_o stratagem_n who_o blow_v up_o foundation_n to_o save_v the_o tedious_a peck_v at_o all_o the_o part_n of_o the_o superstructure_n which_o in_o this_o case_n will_v require_v a_o age_n and_o take_v up_o all_o my_o time_n in_o demolish_n they_o which_o may_v be_v better_o employ_v in_o erect_v something_o that_o may_v be_v useful_a i_o have_v consider_v and_o find_v that_o the_o foundation_n in_o which_o all_o author_n both_o ancient_a and_o modern_a agree_v and_o whereupon_o they_o have_v hitherto_o endeavour_v to_o build_v look_v upon_o it_o as_o firm_a and_o warrantable_a in_o all_o age_n be_v this_o viz._n that_o opium_n operate_v by_o diminish_v or_o disable_n the_o spirit_n mean_v the_o animal_n spirit_n the_o ancient_n affirm_v that_o it_o do_v so_o by_o a_o extreme_a cold_a quality_n etc._n etc._n and_o the_o modern_n who_o observe_v it_o to_o act_n while_o it_o be_v at_o stomach_n by_o affect_v the_o brain_n nerve_n animal_n spirit_n etc._n etc._n and_o conclude_v no_o action_n be_v perform_v without_o contact_n infer_v and_o agree_v because_o no_o visible_a passage_n can_v be_v find_v from_o the_o stomach_n to_o the_o head_n that_o it_o must_v of_o absolute_a necessity_n act_v by_o fume_n vapour_n auras_fw-la or_o effluvium_n send_v up_o out_o of_o the_o stomach_n to_o the_o brain_n nerve_n etc._n etc._n so_o that_o all_o the_o remain_a question_n among_o the_o modern_n be_v which_o way_n those_o fume_n or_o vapour_n do_v the_o feat_n all_o allow_v the_o fume_n do_v it_o one_o say_v that_o they_o stuff_v the_o pore_n of_o the_o brain_n and_o so_o hinder_v the_o generation_n of_o animal_n spirit_n a_o second_o that_o they_o constringed_a and_o close_v the_o pore_n together_o thereby_o hinder_v the_o say_a generation_n a_o three_o that_o they_o fix_v and_o coagulate_v the_o animal_n spirit_n as_o wedelius_n and_o other_o a_o four_o that_o they_o cloud_v the_o animal_n spirit_n a_o five_o that_o they_o act_v as_o a_o poison_n as_o willis_n and_o many_o other_o a_o six_o that_o they_o clog_v the_o animal_n spirit_n by_o adhere_v to_o they_o etc._n etc._n not_o know_v nor_o i_o think_v care_v what_o they_o say_v so_o they_o humour_a their_o own_o imagination_n and_o hypothesise_n though_o utter_o incapable_a of_o solve_v the_o effect_n of_o opium_n especial_o be_v most_o constant_a proper_a and_o genuine_a effect_n for_o how_o can_v a_o cold_a quality_n which_o opium_n never_o have_v cause_v a_o gay_a and_o brisk_a humour_n bravery_n magnanimity_n euphory_n in_o labour_n promptitude_n to_o venus_n etc._n etc._n and_o how_o can_v cloud_n of_o vapour_n hinder_v the_o generation_n of_o animal_n spirit_n by_o stuff_v or_o constr_v the_o pore_n of_o the_o brain_n poison_v fix_v coagulate_v clog_a or_o cloud_v the_o animal_n spirit_n cause_v a_o fine_a ovation_n thereof_o a_o gay_a brave_a courageous_a and_o magnanimous_a disposition_n euphory_n promptitude_n to_o venery_n serenity_n expediteness_n in_o management_n etc._n etc._n which_o be_v as_o have_v be_v say_v the_o constant_a and_o proper_a effect_n of_o opium_n nor_o indeed_o be_v any_o of_o those_o author_n so_o foolhardy_a as_o to_o attempt_v it_o
that_o include_v the_o glandule_n must_v as_o in_o sleep_n which_o relax_n they_o stop_v or_o moderate_v all_o defluxion_n catarrh_n etc._n etc._n because_o they_o be_v not_o sensible_a oâ—_n the_o irritation_n of_o the_o humour_n by_o quantity_n or_o quality_n which_o irritation_n cause_v the_o defluxion_n or_o catarrh_n by_o exciting_a the_o membrane_n to_o contract_v and_o thereby_o to_o squeeze_v out_o the_o humour_n contain_v in_o the_o glandule_n four_o the_o composure_n of_o the_o spirit_n be_v procure_v main_o by_o sleep_n which_o all_o loss_n of_o spirit_n as_o be_v show_v incline_v we_o to_o so_o bleed_v which_o diminish_v the_o spirit_n compose_v their_o fury_n in_o fever_n delirium_n madness_n etc._n etc._n five_o perspiration_n be_v cause_v by_o nothing_o more_o than_o sleep_v for_o we_o perspire_v twice_o as_o much_o in_o sleep_n as_o when_o we_o watch_v as_o be_v most_o manifest_o demonstrable_a by_o the_o statick_a experiment_n of_o weigh_v people_n nor_o be_v perspiration_n ever_o so_o great_a as_o in_o deliquium_n syncopes_fw-la leipothymy_n and_o such_o like_a deadish_fw-mi case_n which_o be_v cause_v by_o diminish_v or_o disable_n of_o the_o spirit_n nay_o it_o be_v so_o in_o animal_n quite_o dead_a for_o a_o little_a time_n while_o they_o be_v hot_a as_o be_v evident_a by_o like_a statick_a demonstration_n the_o true_a cause_n of_o which_o be_v relaxation_n of_o the_o pore_n skin_n etc._n etc._n for_o want_n of_o spirit_n to_o contract_n and_o constringe_v they_o as_o shall_v be_v full_o prove_v hereafter_o by_o god_n help_n these_o thing_n be_v doubtless_o the_o occasion_n of_o that_o hypothesis_n of_o diminish_v or_o disable_n the_o spirit_n by_o opium_n but_o how_o likely_a be_v they_o to_o err_v by_o establish_v it_o without_o any_o consideration_n of_o its_o enliven_a encourage_v and_o brisk_a effect_n as_o ovation_n of_o the_o spirit_n gaity_n bravery_n magnanimity_n euphory_n promptitude_n to_o venery_n etc._n etc._n which_o can_v never_o be_v solve_v by_o diminution_n or_o disability_n of_o the_o spirit_n till_o depression_n and_o elevation_n thereof_o be_v reconcilable_a and_o consistent_a at_o the_o same_o time_n in_o the_o same_o subject_n which_o can_v never_o be_v till_o disable_n and_o not_o disable_n be_v the_o same_o thing_n have_v not_o we_o then_o good_a reason_n to_o suspect_v that_o general_a foundation_n of_o diminish_v or_o disable_n the_o spirit_n by_o opium_n which_o be_v lay_v by_o such_o as_o never_o consider_v any_o thing_n of_o its_o generous_a and_o sprightly_a effect_n which_o as_o have_v be_v show_v be_v its_o constant_a and_o therefore_o most_o proper_a and_o genuine_a effect_n who_o can_v doubt_v then_o but_o they_o must_v err_v in_o lay_v a_o foundation_n quite_o contrary_a to_o the_o very_a property_n of_o opium_n 5._o i_o observe_v that_o all_o our_o modern_a author_n and_o physician_n receive_v the_o knowledge_n of_o opium_n its_o effect_n and_o uses_n from_o those_o ancient_n do_v use_v it_o only_o for_o the_o same_o end_n and_o purpose_v as_o they_o do_v and_o that_o our_o modern_a author_n live_v in_o these_o western_a part_n of_o the_o world_n very_o remote_a from_o the_o eastern_a country_n where_o it_o be_v use_v common_o and_o in_o large_a dose_n by_o people_n in_o health_n in_o the_o daytime_n to_o enliven_v invigorate_a and_o encourage_v they_o and_o cause_v the_o brave_a generous_a and_o magnanimous_a effect_n aforemention_v viz._n courage_n euphory_n etc._n etc._n and_o find_v no_o physician_n that_o go_v before_o they_o to_o mention_v these_o noble_a cordial_a and_o glorious_a effect_n and_o if_o they_o do_v at_o any_o time_n slight_o touch_v they_o to_o do_v it_o with_o all_o imaginable_a disregard_n neglect_v and_o contempt_n as_o if_o there_o be_v no_o heed_n to_o be_v take_v of_o they_o but_o as_o idle_a tale_n and_o improbable_a story_n be_v contrary_a and_o utter_o as_o they_o think_v inconsistent_a and_o irreconcilable_a with_o the_o daily_a and_o most_o notorious_a effect_n of_o opium_n observe_v among_o we_o and_o to_o the_o universal_a opinion_n of_o all_o author_n who_o state_v opium_n to_o be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n which_o can_v not_o produce_v as_o they_o conclude_v such_o contradictory_n and_o therefore_o to_o they_o utter_o incredible_a effect_n and_o fabulons_a flam_n arise_v as_o they_o fancy_v from_o some_o silly_a error_n as_o want_v of_o due_a observation_n in_o traveller_n mistake_a discourse_n and_o the_o like_a so_o that_o as_o the_o say_n be_v they_o let_v they_o in_o at_o one_o ear_n and_o out_o at_o the_o other_o there_o be_v no_o such_o contrary_a effect_n of_o any_o one_o thing_n to_o be_v observe_v in_o the_o whole_a creation_n and_o they_o be_v well_o assure_v of_o the_o other_o effect_n by_o daily_a experience_n and_o have_v never_o observe_v those_o lively_a effect_n for_o the_o several_a plain_a reason_n that_o you_o will_v meet_v in_o the_o follow_a paragraph_n have_v no_o cause_n to_o alter_v their_o opinion_n when_o all_o thing_n seem_v to_o they_o to_o make_v for_o their_o hypothesis_n for_o want_v of_o a_o notion_n of_o those_o brisk_a effect_n 6._o i_o observe_v that_o those_o brisk_a effect_n of_o opium_n be_v not_o take_v notice_n of_o by_o our_o physician_n nor_o indeed_o all_o thing_n consider_v do_v i_o well_o see_v how_o they_o shall_v without_o get_v out_o of_o the_o common_a road_n of_o observe_v which_o be_v sometime_o as_o i_o have_v find_v very_o useful_a upon_o such_o occasion_n for_o first_o opium_n be_v seldom_o if_o ever_o give_v in_o these_o western_a nation_n but_o to_o sick_a people_n as_o the_o ancient_n do_v who_o be_v utter_o incapable_a of_o those_o brisk_a effect_n or_o at_o least_o to_o any_o remarkable_a degree_n that_o may_v call_v for_o a_o particular_a or_o special_a advertency_n or_o attention_n without_o which_o they_o pass_v off_o as_o they_o come_v without_o any_o reflection_n thereupon_o and_o so_o signify_v nothing_o as_o if_o they_o have_v never_o happen_v second_o we_o as_o the_o ancient_n do_v general_o give_v opium_n when_o people_n be_v go_v to_o bed_n by_o which_o mean_v all_o opportunity_n of_o observation_n be_v lose_v because_o darkness_n and_o be_v alone_o hide_v or_o hinder_v the_o show_v of_o any_o such_o effect_n and_o the_o physician_n who_o only_a business_n it_o be_v to_o be_v more_o curious_a in_o such_o matter_n be_v go_v to_o his_o own_o rest_n though_o if_o he_o be_v present_a not_o likely_a to_o take_v any_o observation_n of_o such_o matter_n whereof_o he_o have_v least_o thought_n or_o belief_n as_o be_v in_o his_o opinion_n contrary_a to_o all_o reason_n sense_n experience_n and_o the_o opinion_n of_o all_o author_n of_o the_o stupefactive_a quality_n of_o opium_n in_o which_o they_o all_o agree_v three_o opium_n be_v as_o be_v say_v give_v in_o these_o country_n to_o cause_n sleep_n or_o such_o effect_n to_o which_o sleep_n conduce_v as_o compose_v the_o spirit_n cause_v indolence_n stop_v flux_n and_o promote_a perspiration_n and_o therefore_o always_o give_v with_o all_o careful_a direction_n and_o injunction_n that_o may_v conduce_v to_o that_o end_n as_o go_v to_o bed_n lie_v still_o put_v out_o light_n keep_v silence_n etc._n etc._n which_o concur_v with_o the_o opium_n cause_n sleep_n which_o be_v utter_o inconsistent_a with_o show_v any_o of_o those_o lively_a effect_n that_o belong_v only_o to_o a_o wake_a person_n to_o do_v so_o that_o all_o opportunity_n of_o observation_n be_v utter_o preclude_v now_o all_o the_o premise_n consider_v it_o can_v be_v conceive_v that_o such_o as_o set_v their_o mind_n upon_o contrary_a effect_n and_o expect_v no_o other_o much_o less_o contrary_a one_o against_o which_o also_o they_o be_v high_o prejudice_v by_o their_o reason_n experience_n and_o read_v shall_v observe_v such_o brisk_a effect_n if_o they_o do_v happen_v and_o how_o can_v a_o brisk_a humour_n courage_n easy_a undergo_n of_o labour_n promptitude_n to_o venus_n etc._n etc._n be_v observe_v in_o sick_a and_o infirm_a people_n lie_v in_o bed_n alone_z and_o in_o the_o dark_a or_o which_o render_v it_o utter_o impossible_a while_o they_o be_v asleep_a and_o the_o thing_n itself_o disbelieved_a and_o esteem_v contrary_a to_o common_a sense_n and_o the_o universal_a sentiment_n of_o the_o learned_a and_o all_o other_o therefore_o 7._o if_o after_o all_o any_o such_o brisk_a effect_n do_v ever_o happen_v it_o must_v be_v either_o not_o regard_v or_o if_o observe_v which_o be_v no_o way_n likely_a as_o be_v show_v you_o may_v be_v sure_a for_o the_o many_o plain_a reason_n and_o cause_n aforesaid_a that_o it_o be_v not_o impute_v to_o stupify_a opium_n as_o all_o esteem_v it_o but_o to_o any_o other_o cause_n or_o accident_n rather_o than_o to_o a_o thing_n well_o know_v to_o have_v quite_o contrary_a effect_n for_o instance_n if_o the_o sick_a person_n happen_v to_o be_v
good_a humour_a of_o which_o he_o be_v seldom_o capable_a and_o utter_o incapable_a of_o all_o or_o most_o of_o the_o other_o brisk_a effect_n as_o euphory_n promptitude_n to_o venus_n exertion_n of_o courage_n etc._n etc._n it_o be_v either_o pass_v by_o as_o a_o ordinary_a thing_n of_o course_n and_o so_o not_o heed_v or_o else_o impute_v to_o refreshment_n by_o sleep_n ease_n from_o pain_n or_o some_o amendment_n as_o to_o the_o disease_n or_o indeed_o to_o any_o thing_n rather_o than_o dispiriting_n and_o stupify_a opium_n that_o be_v so_o far_o in_o all_o opinion_n from_o exciting_a the_o spirit_n that_o all_o affirm_v conclude_v and_o agree_v that_o it_o diminish_v or_o disable_v they_o the_o like_a be_v to_o be_v say_v of_o any_o of_o the_o lively_a effect_n in_o case_n they_o happen_v and_o be_v observe_v though_o i_o do_v not_o see_v how_o they_o can_v so_o at_o least_o as_o any_o slander_n by_o will_v refer_v it_o to_o opium_n beside_o that_o as_o to_o some_o of_o the_o brisk_a effect_n especial_o that_o of_o venery_n great_a dose_n be_v requisite_a to_o render_v it_o any_o thing_n remarkable_a than_o be_v use_v in_o these_o western_a part_n and_o that_o modesty_n will_v much_o hinder_v the_o discovery_n of_o this_o effect_n be_v it_o not_o therefore_o very_o manifest_a that_o i_o have_v great_a cause_n to_o suspect_v that_o both_o ancient_n and_o modern_a physician_n consider_v thing_n by_o half_n since_o they_o do_v not_o take_v the_o most_o genuine_a property_n into_o their_o consideration_n and_o that_o they_o lay_v their_o foundation_n upon_o the_o most_o contrary_a effect_n to_o they_o it_o follow_v then_o that_o the_o general_a supposition_n of_o all_o the_o learned_a can_v no_o more_o solve_v the_o true_a property_n of_o opium_n in_o any_o probability_n than_o give_v the_o reason_n why_o fire_n harden_v clay_n can_v explain_v why_o it_o soften_v wax_n the_o reason_n do_v i_o say_v i_o shall_v have_v say_v than_o give_v the_o wrong_a reason_n why_o it_o harden_v clay_n show_v how_o it_o soften_v wax_n for_o it_o will_v appear_v in_o the_o follow_a chapter_n that_o they_o give_v no_o right_a reason_n for_o any_o effect_n of_o opium_n even_o those_o they_o ever_o allow_v to_o be_v its_o effect_n nor_o lay_v any_o true_a foundation_n to_o explain_v the_o least_o mean_a and_o plain_a effect_n thereof_o forasmuch_o as_o all_o their_o supposition_n be_v so_o false_a that_o there_o never_o be_v any_o such_o thing_n as_o they_o lie_v down_o to_o explain_v the_o effect_n of_o opium_n viz._n 1._o no_o such_o thing_n as_o a_o cold_a quality_n in_o opium_n 2._o no_o such_o thing_n as_o fume_n etc._n etc._n fly_v from_o opium_n to_o the_o brain_n while_o it_o be_v at_o stomach_n 3._o no_o such_o thing_n as_o diminish_v or_o disable_n the_o animal_n spirit_n by_o opium_n any_o way_n whatsoever_o of_o which_o in_o their_o order_n in_o the_o follow_a chapter_n chap._n ix_o it_o be_v prove_v that_o opium_n have_v no_o cold_a quality_n to_o diminish_v or_o disable_v the_o spirit_n thereby_o have_v show_v just_a cause_n of_o my_o suspicion_n of_o that_o universal_a foundation_n of_o opium_n diminish_v or_o disable_n the_o spirit_n i_o will_v now_o proceed_v to_o a_o more_o strict_a examination_n thereof_o beginning_n with_o the_o opinion_n of_o the_o ancient_n who_o affirm_v that_o opium_n diminish_v or_o disable_v the_o spirit_n by_o a_o extreme_a cold_a quality_n i_o confess_v that_o much_o may_v be_v do_v towards_o the_o diminish_n or_o disable_n the_o spirit_n by_o opium_n if_o it_o have_v such_o a_o cold_a quality_n as_o the_o ancient_n attribute_v to_o it_o for_o than_o it_o must_v be_v such_o a_o coldness_n as_o the_o cold_a thing_n either_o actual_a or_o potential_a bear_v no_o proportion_n to_o for_o ice_n snow_n etc._n etc._n bear_v no_o proportion_n to_o it_o in_o cause_v the_o same_o effect_n by_o a_o cold_a quality_n it_o be_v the_o manner_n of_o the_o ancient_n implicit_o to_o believe_v and_o subscribe_v to_o what_o their_o great_a author_n and_o master_n in_o physic_n or_o philosophy_n teach_v they_o who_o they_o adore_v as_o infallible_a god_n as_o soon_o as_o their_o mortality_n prove_v the_o contrary_a which_o be_v as_o absurd_a as_o assert_v tha_z opium_n which_o be_v one_o of_o the_o hot_a thing_n that_o vegetable_n afford_v be_v extreme_a cold_a bless_a be_v god_n for_o our_o light_n in_o religion_n and_o liberty_n in_o philosophy_n therefore_o some_o such_o admire_a author_n or_o great_a master_n in_o physic_n have_v assert_v that_o opium_n act_v by_o a_o extreme_a cold_a quality_n all_o do_v implicit_o subscribe_v to_o it_o the_o devil_n who_o they_o worship_v can_v not_o though_o a_o deceiver_n from_o the_o beginning_n impose_v more_o upon_o their_o faith_n than_o in_o cause_v they_o for_o i_o can_v think_v but_o it_o be_v some_o such_o evil_a power_n to_o believe_v that_o opium_n be_v cold_a against_o all_o the_o evidence_n of_o sense_n and_o experience_n he_o may_v have_v as_o well_o tell_v they_o that_o hell_n fire_n have_v all_o the_o property_n of_o common_a culinary_a fire_n and_o yet_o nothing_o more_o refresh_v by_o its_o cold_a quality_n for_o as_o many_o of_o our_o sense_n as_o can_v take_v notice_n of_o heat_n and_o cold_a do_v plain_o inform_v we_o that_o it_o be_v very_o hot_a in_o itself_o and_o effect_n for_o 1._o it_o be_v taste_n be_v very_o bitter_a rank_a vehement_o hot_a burn_a and_o bite_v all_o which_o quality_n be_v infallible_a sign_n of_o great_a heat_n and_o the_o better_a the_o opium_n be_v the_o more_o intense_a be_v those_o quality_n nay_o it_o be_v observe_v that_o its_o very_a virtue_n be_v strict_o combine_v to_o or_o consist_v in_o those_o quality_n especial_o bitterness_n which_o if_o lose_v the_o virtue_n be_v go_v as_o be_v common_o observe_v and_o easy_o observable_a it_o be_v a_o wise_a fetch_v of_o amatus_fw-la lusitanus_n in_o defence_n of_o its_o cold_a quality_n to_o attribute_v all_o its_o bitterness_n to_o glaucium_fw-la that_o be_v mix_v therewith_o whereas_o glaucium_fw-la always_o give_v a_o yellow_a tincture_n to_o water_n and_o opium_n a_o red_a but_o the_o opium_n that_o give_v no_o yellow_a tincture_n be_v bitter_a also_o yea_o that_o be_v most_o bitter_a that_o give_v the_o red_a tincture_n how_o come_v theban_a opium_n and_o indeed_o all_o other_o opium_n to_o be_v bitter_a before_o any_o thing_n be_v mix_v with_o it_o how_o inadvertent_o absurd_a people_n will_v be_v to_o defend_v absurdity_n it_o be_v pretty_a to_o see_v how_o they_o will_v expose_v themselves_o to_o defend_v a_o false_a opinion_n 2._o it_o be_v smell_n which_o be_v very_a rank_n strong_a hot_a and_o such_o as_o thing_n high_o impregnate_v with_o volatile_a salt_n and_o sulphur_n the_o two_o hot_a principle_n in_o nature_n do_v afford_v it_o be_v from_o volatile_a salt_n that_o cantharides_n pismire_n spear-wort_n crowsfoot_n etc._n etc._n be_v so_o very_o hot_a as_o to_o blister_v or_o exulcerate_v and_o be_v not_o all_o hot_a spirit_n such_o upon_o the_o account_n of_o their_o sulphur_n as_o spirit_n of_o wine_n brandy_n etc._n etc._n 3._o the_o best_a and_o strong_a opium_n will_v also_o exulcerate_v as_o all_o author_n agree_v which_o only_a fire_n or_o such_o thing_n as_o have_v the_o particle_n of_o fire_n lodge_v in_o they_o as_o lixiviate_n etc._n etc._n or_o the_o hot_a thing_n in_o nature_n will_v do_v as_o cantharides_n spear-wort_n etc._n etc._n it_o be_v 4._o for_o the_o like_a reason_n a_o psilothrick_n or_o causer_n of_o hair_n to_o fall_v which_o only_a lime_n orpâ—ment_n and_o the_o hot_a thing_n do_v cause_n 5._o it_o be_v inflammable_a which_o only_o sulphurecus_fw-la thing_n be_v 6._o it_o cause_v a_o sense_n of_o a_o vehement_a heat_n at_o stomach_n though_o take_v but_o in_o the_o quantity_n of_o a_o drachm_n 7._o it_o cause_v dryness_n of_o the_o mouth_n and_o thirst_v though_o take_v but_o in_o the_o quantity_n of_o 3_o grain_n which_o nothing_o do_v but_o hot_a thing_n 8._o it_o discuss_n and_o all_o discusser_n be_v hot_a for_o it_o be_v by_o heat_n that_o they_o do_v discuss_v as_o spirit_n of_o wine_n cummin-seed_n volatile_a salt_n and_o all_o hot_a spirit_n 9_o it_o soon_o operate_v and_o in_o a_o small_a quantity_n which_o be_v a_o infallible_a proof_n of_o the_o activity_n of_o its_o part_n which_o argue_v heat_n not_o cold._a 10._o it_o cause_v a_o gay_a pleasant_a and_o merry_a humour_n which_o only_a wine_n and_o hot_a liquor_n etc._n etc._n do_v and_o one_o grain_n of_o opium_n will_v cause_v they_o as_o much_o as_o several_a glass_n of_o wine_n which_o argue_v that_o its_o heat_n be_v much_o great_a 11._o i_o will_v fain_o know_v how_o or_o see_v any_o instance_n of_o any_o cold_a thing_n raise_v the_o spirit_n cause_v courage_n magnanimity_n enable_v people_n to_o labour_n journey_n etc._n
any_o regular_a thinker_n without_o my_o help_n but_o all_o be_v not_o such_o and_o the_o prejudices_fw-la general_n and_o inveterate_a and_o of_o some_o thousand_o of_o year_n stand_v have_v continue_v through_o all_o age_n to_o this_o day_n and_o i_o will_v fain_o quite_o put_v out_o this_o false_a light_n that_o like_a will_n of_o the_o wisp_n have_v bring_v many_o a_o man_n into_o the_o pit_n of_o destruction_n or_o grave_a while_o physician_n be_v guide_v thereby_o therefore_o it_o be_v no_o slight_a work_n to_o undeceive_v many_o and_o a_o very_a good_a work_n if_o possible_a to_o undeceive_v all_o i_o will_v left_a what_o i_o have_v say_v be_v not_o sufficient_a to_o that_o end_n add_v somewhat_o more_o to_o the_o same_o purpose_n though_o i_o doubt_v some_o will_v not_o be_v convince_v till_o i_o show_v they_o how_o thing_n while_n at_o stomach_n may_v cause_v all_o the_o effect_n of_o opium_n by_o a_o sensible_a operation_n without_o the_o help_n of_o fume_n vapour_n effluvia_n aura_n or_o any_o any_o such_o thing_n which_o have_v be_v the_o asylum_n of_o the_o shortsighted_a that_o can_v see_v no_o other_o mean_n and_o therefore_o as_o be_v say_v conclude_v thing_n must_v be_v as_o they_o think_v presume_v that_o nothing_o can_v be_v that_o they_o do_v not_o see_v a_o special_a inference_n and_o a_o very_a improve_n one_o which_o must_v cause_v people_n never_o to_o seek_v for_o any_o thing_n for_o why_o shall_v they_o that_o think_v there_o be_v nothing_o but_o what_o they_o see_v look_v any_o far_o to_o proceed_v then_o 14._o it_o be_v agree_v on_o all_o hand_n as_o i_o take_v it_o that_o the_o animal_n spirit_n be_v not_o generate_v till_o there_o be_v a_o appulse_n of_o the_o blood_n at_o the_o brain_n can_v it_o therefore_o be_v imagine_v that_o indulgent_a and_o wise_a nature_n shall_v contrive_v a_o speedy_a way_n to_o destroy_v diminish_v or_o disable_v the_o spirit_n by_o fume_n and_o vapour_n out_o of_o the_o stomach_n than_o to_o generate_v they_o these_o be_v not_o the_o way_n of_o equal_a nature_n which_o destroy_v and_o generate_v by_o the_o same_o road_n so_o that_o if_o animal_n spirit_n be_v generate_v by_o the_o blood_n they_o be_v diminish_v by_o some_o defect_n therein_o as_o want_v of_o matter_n in_o the_o blood_n for_o that_o purpose_n the_o blood_n not_o arrive_v at_o the_o brain_n and_o the_o like_a note_v that_o i_o speak_v in_o the_o last_o paragraph_n of_o diminish_v or_o destroy_v not_o bare_a disable_n the_o spirit_n for_o the_o spirit_n or_o sensitive_a soul_n may_v be_v depress_v or_o disable_v for_o some_o time_n and_o excite_v or_o elevate_v by_o other_o mean_n than_o that_o of_o the_o blood_n as_o by_o pleasure_n or_o displeasure_n joy_n or_o grief_n etc._n etc._n thus_o good_a news_n or_o the_o pleasure_n of_o any_o of_o the_o sense_n enliven_v invigorate_a or_o elevate_v the_o spirit_n or_o sensitive_a soul_n in_o a_o moment_n this_o be_v the_o way_n that_o god_n have_v provide_v for_o we_o upon_o sudden_a exigency_n deliquium_n lepothymy_n etc._n etc._n and_o thus_o cordial_n work_v so_o speedy_o as_o you_o will_v find_v hereafter_o so_o may_v there_o be_v a_o sudden_a depression_n of_o the_o spirit_n as_o by_o ill_a news_n pain_n etc._n etc._n which_o if_o you_o will_v be_v please_v to_o remember_v will_v much_o illustrate_a thing_n hereafter_o 15._o the_o ordinary_a strainer_n of_o the_o body_n be_v so_o order_v that_o they_o will_v not_o admit_v particle_n of_o another_o figure_n especial_o if_o large_a than_o the_o proper_a particle_n much_o more_o shall_v it_o be_v so_o with_o the_o principal_a strainer_n of_o the_o whole_a body_n i_o mean_v the_o brain_n both_o for_o its_o safety_n and_o of_o the_o whole_a which_o depend_v upon_o the_o animal_n spirit_n that_o be_v strain_v or_o separate_v from_o the_o blood_n in_o the_o brain_n therefore_o the_o particle_n of_o opium_n which_o be_v esteem_v gross_a by_o all_o however_o be_v more_o so_o than_o the_o most_o tenuious_a animal_n spirit_n can_v enter_v into_o the_o pore_n of_o the_o brain_n to_o diminish_v or_o disable_v the_o animal_n spirit_n in_o case_n its_o fume_v arrive_v there_o 16._o it_o be_v never_o the_o method_n of_o nature_n to_o send_v thing_n crude_a unprepared_a and_o undigested_a into_o the_o inmost_a and_o principal_a recess_n and_o part_n of_o the_o body_n without_o pass_v gradual_o by_o the_o several_a digestion_n concoction_n change_n percolation_n circulation_n etc._n etc._n preparatory_a thereunto_o therefore_o it_o will_v not_o permit_v crude_a and_o indigested_a fume_n any_o access_n to_o the_o brain_n till_o they_o have_v as_o it_o be_v perform_v their_o quarentine_n elsewhere_o nor_o will_v nature_n which_o always_o act_v consentaneous_a to_o itself_o provide_v any_o passage_n for_o such_o rude_a and_o crude_a foreigner_n and_o stranger_n to_o ravage_v the_o principal_a part_n of_o a_o animal_n 17._o they_o can_v pass_v by_o the_o artery_n which_o carry_v nothing_o out_o of_o the_o stomach_n but_o all_o into_o it_o or_o towards_o it_o and_o that_o with_o a_o violent_a motion_n which_o oppose_v any_o thing_n that_o will_v pass_v that_o way_n 18._o nor_o by_o the_o vein_n which_o carry_v nothing_o into_o the_o brain_n but_o if_o they_o enter_v the_o vein_n at_o stomach_n they_o must_v thence_o pass_v into_o the_o right_a ventricle_n of_o the_o heart_n where_o be_v rarefy_v by_o heat_n they_o must_v take_v up_o much_o room_n and_o sad_o discompose_v the_o motion_n of_o the_o blood_n and_o also_o enter_v this_o principal_a part_n in_o a_o crude_a condition_n though_o much_o better_a able_a to_o bear_v they_o than_o the_o brain_n then_o must_v they_o pass_v into_o the_o lung_n where_o you_o may_v be_v sure_a they_o will_v be_v so_o saucy_a as_o to_o take_v up_o the_o uppermost_a room_n and_o how_o they_o will_v be_v bring_v down_o again_o into_o the_o left_a ventricle_n of_o the_o heart_n which_o they_o must_v vouchsase_v to_o do_v before_o they_o can_v get_v into_o the_o brain_n none_o can_v tell_v there_o then_o must_v they_o stick_v and_o cause_v a_o asthma_n unless_o the_o man_n have_v the_o good_a luck_n to_o be_v rid_v of_o these_o rover_n by_o othing_n and_o then_o joy_n be_v with_o they_o as_o there_o wiâ—_n be_v when_o they_o be_v go_v they_o be_v lose_v and_o never_o arrive_v at_o the_o brain_n and_o if_o it_o can_v be_v conceive_v that_o they_o condescend_v to_o come_v down_o from_o the_o lung_n contrary_a to_o their_o levity_n which_o be_v not_o to_o be_v think_v what_o prank_n must_v they_o play_v in_o 〈◊〉_d leave_v ventricle_n of_o the_o heart_n and_o what_o at_o 〈◊〉_d consider_v it_o can_v bear_v the_o 〈◊〉_d 〈◊〉_d 〈◊〉_d have_v be_v show_v whereas_o in_o this_o case_n there_o must_v be_v a_o continual_a stream_n thereof_o and_o consequent_o a_o discontinuance_n of_o the_o blood_n and_o its_o motion_n see_v then_o how_o little_a think_v they_o must_v have_v that_o assert_v it_o be_v convey_v with_o the_o blood_n either_o to_o the_o vein_n or_o artery_n 19_o nor_o by_o the_o lymphduct_n for_o than_o they_o must_v contrary_a to_o their_o natural_a levity_n descend_v into_o the_o receptaculum_fw-la chyli_n and_o out_o of_o the_o subclavial_o into_o the_o right_a ventricle_n of_o the_o heart_n and_o afterward_o run_v all_o that_o wild_a risque_n mention_v in_o the_o last_o paragraph_n which_o be_v show_v to_o be_v impossible_a 20._o nor_o by_o the_o nerve_n for_o than_o they_o must_v either_o run_v up_o in_o the_o road_n of_o the_o animal_n spirit_n or_o in_o some_o by-way_n if_o they_o pass_v by_o the_o road_n of_o the_o spirit_n then_o must_v the_o spirit_n be_v stop_v for_o that_o time_n which_o be_v no_o short_a one_o and_o we_o suffer_v a_o paralysis_n of_o the_o stomach_n all_o that_o time_n or_o be_v much_o disturb_v and_o interrupt_v then_o shall_v we_o have_v convulsion_n or_o at_o least_o some_o degree_n of_o a_o paralysis_n of_o the_o stomach_n and_o if_o they_o pass_v by_o some_o by-way_n or_o road_n beside_o that_o of_o the_o animal_n spirit_n then_o must_v it_o be_v a_o full_a or_o a_o empty_a one_o if_o full_a that_o humour_n as_o suppose_v a_o succus_fw-la nutricius_fw-la for_o once_o must_v be_v disturb_v and_o discontinue_v as_o the_o animal_n spirit_n be_v show_v to_o be_v and_o if_o empty_a it_o will_v follow_v that_o nature_n have_v void_a and_o useless_a duct_n which_o none_o ever_o have_v the_o folly_n or_o confidence_n to_o assert_v or_o that_o nature_n contrive_v they_o for_o that_o purpose_n which_o be_v as_o have_v be_v show_v direct_o against_o its_o method_n and_o advantage_n but_o after_o all_o whither_o will_v you_o have_v they_o march_v in_o this_o by-road_n for_o they_o can_v not_o mix_v or_o communicate_v as_o good_a luck_n be_v with_o the_o spirit_n and_o if_o they_o do_v it_o be_v
of_o it_o and_o what_o be_v to_o be_v say_v thereof_o more_o at_o large_a hereafter_o i_o say_v then_o that_o hot_a spirituous_a cordial_n for_o such_o indeed_o all_o proper_a cordial_n be_v as_o brandy_n dr._n stephens_n water_n and_o suchlike_a have_v sulphureous_a particle_n so_o prepare_v and_o dispose_v towards_o heat_n or_o fire_n that_o they_o be_v as_o it_o be_v in_o potentia_fw-la proxima_fw-la or_o next_o disposition_n thereto_o be_v mighty_a apt_a to_o contract_v a_o heat_n as_o you_o find_v by_o spirit_n of_o wine_n or_o brandy_n keep_v the_o least_o time_n in_o a_o warm_a place_n or_o to_o come_v close_o to_o the_o matter_n in_o your_o mouth_n wherein_o be_v actuate_v by_o its_o heat_n they_o will_v as_o in_o a_o instant_n grow_v so_o hot_a and_o active_a that_o you_o can_v hardly_o bear_v they_o because_o particle_n of_o heat_n which_o penetrate_v any_o metal_n glass_n etc._n etc._n immediate_o as_o soon_o as_o apply_v thereto_o will_v much_o more_o easy_o and_o soon_o penetrate_v our_o soft_a part_n at_o mouth_n or_o the_o crusta_fw-la carnosa_fw-la at_o stomach_n and_o so_o reach_v the_o most_o sensile_a coat_n thereof_o please_v comfort_a and_o exciting_a the_o spiritus_fw-la insitos_fw-la as_o in_o a_o moment_n by_o their_o spirituous_a heat_n which_o we_o actual_o feel_v and_o sensible_o find_v to_o please_v and_o comfort_v the_o stomach_n but_o if_o some_o purge_v tincture_n have_v be_v put_v into_o the_o cordial_n or_o brandy_n this_o will_v not_o have_v soak_v through_o the_o crusta_fw-la carnosa_fw-la under_o some_o time_n and_o consequent_o not_o operate_v till_o it_o have_v this_o may_v be_v most_o manifest_o illustrate_v by_o some_o hot_a brandy_n or_o indeed_o any_o hot_a liquid_a put_v into_o a_o porous_a dish_n set_v upon_o one_o hand_n which_o present_o warm_v it_o but_o if_o the_o liquid_a be_v tinge_v with_o any_o thing_n that_o tincture_n will_v not_o reach_v the_o hand_n till_o the_o liquor_n which_o be_v its_o vehicle_n soak_v through_o which_o may_v be_v in_o a_o hour_n more_o or_o less_o according_a to_o the_o porosity_n of_o the_o wood_n which_o tincture_n be_v to_o be_v compare_v to_o the_o purgative_n at_o stomach_n hence_o it_o follow_v that_o all_o cordial_n shall_v be_v a_o spirituous_a liquid_a if_o intend_v for_o sudden_a refreshment_n which_o experience_n have_v teach_v and_o be_v give_v actual_o warm_v if_o a_o very_a nimble_a comfort_n be_v require_v though_o the_o great_a heat_n of_o the_o stomach_n above_o that_o of_o the_o mouth_n will_v general_o be_v sufficient_a thus_o may_v the_o stomach_n be_v please_v and_o comfort_v grieve_v and_o purge_v with_o the_o same_o draught_n but_o gracious_a providence_n have_v give_v the_o start_n to_o the_o cordial_n which_o immediate_o comfort_v we_o as_o a_o heater_n 30._o if_o opium_n operate_v by_o such_o fume_n it_o will_v at_o least_o in_o a_o liquid_a form_n begin_v its_o operation_n as_o soon_o as_o it_o be_v at_o stomach_n for_o it_o will_v begin_v to_o send_v up_o fume_n as_o soon_o as_o it_o begin_v to_o be_v warm_a which_o be_v present_o and_o be_v at_o a_o very_a considerable_a height_n of_o fume_v and_o consequent_o of_o operation_n in_o one_o minute_n which_o be_v about_o the_o space_n of_o seventy_o ordinary_a pulse_n but_o we_o do_v not_o find_v it_o begin_v to_o operate_v in_o that_o form_n under_o twenty_o thirty_o or_o forty_o minute_n which_o be_v much_o about_o the_o time_n that_o a_o more_o agreeable_a and_o not_o nauseated_a vomitive_a or_o purger_n begin_v to_o affect_v the_o sensile_a coat_n of_o the_o stomach_n and_o give_v intimation_n of_o their_o so_o do_v all_o which_o and_o the_o sense_n of_o pleasure_n that_o we_o actual_o then_o seel_v at_o stomach_n make_v it_o probable_a that_o it_o operate_v by_o affect_v the_o stomach_n pleasant_o and_o comfortable_o after_o the_o manner_n of_o generous_a wine_n as_o purger_n and_o vomatives_n do_v by_o affect_v it_o grievous_o all_o of_o they_o except_o the_o wine_n that_o please_v and_o comfort_v soon_o because_o of_o its_o particle_n of_o heat_n gain_v by_o fermentation_n operate_a much_o in_o the_o same_o time_n because_o they_o take_v like_o leisure_n to_o soak_v through_o the_o crusta_fw-la carnosa_fw-la to_o the_o sensile_a coat_n of_o the_o stomach_n 31._o all_o sensitive_a pleasure_n comfort_n etc._n etc._n be_v receive_v by_o the_o sense_n and_o though_o any_o part_n be_v some_o way_n benefit_v that_o have_v no_o sense_n no_o comfort_n will_v be_v perceive_v without_o perception_n none_o can_v say_v that_o he_o be_v comfort_v what_o fit_a part_n be_v there_o to_o be_v please_v and_o comfort_v by_o sensation_n than_o the_o stomach_n which_o have_v such_o exquisite_a sense_n that_o it_o can_v discern_v the_o vomitory_n particle_n in_o infusion_n of_o the_o grocus_n or_o regulus_n of_o antimony_n which_o no_o sensation_n but_o that_o at_o stomach_n can_v discern_v and_o so_o small_a that_o a_o thousand_o vomitory_n make_v thereof_o by_o infusion_n do_v not_o sensible_o diminish_v the_o grocus_n or_o regulus_n as_o to_o weight_n or_o bulk_n nor_o can_v i_o conceive_v where_o any_o sensible_a comfort_n can_v be_v perceive_v by_o a_o spoonful_n of_o cordial_n but_o at_o stomach_n where_o it_o actual_o be_v and_o upon_o who_o coat_n it_o immediate_o insist_o be_v it_o not_o there_o that_o we_o feel_v the_o comfort_n and_o where_o shall_v we_o find_v it_o but_o there_o what_o will_v the_o effluvium_n of_o a_o spoonful_n signify_v if_o mix_v with_o 100000_o time_n as_o much_o insensile_a blood_n and_o what_o part_n beside_o the_o stomach_n that_o the_o blood_n touch_v can_v be_v sensible_a of_o it_o so_o that_o if_o effluvium_n be_v grant_v it_o be_v thither_o they_o must_v return_v to_o cause_v any_o considerable_a pleasure_n or_o comfort_n but_o what_o need_v any_o reâ—urn_n of_o the_o inconsiderable_a effluvia_fw-la when_o the_o main_a body_n of_o the_o cordial_n yea_o all_z lie_v upon_o the_o stomach_n already_o i_o must_v forbear_v run_v into_o the_o business_n of_o other_o chapter_n have_v be_v tedious_a enough_o upon_o the_o subject_a of_o this_o and_o the_o rather_o because_o it_o be_v so_o general_a and_o so_o root_v a_o opinion_n in_o the_o mind_n of_o man_n in_o all_o age_n and_o in_o all_o sect_n of_o physician_n and_o natural_a philosopher_n that_o i_o can_v not_o say_v too_o much_o to_o endeavour_v to_o free_v the_o world_n from_o the_o slavery_n of_o such_o a_o imposition_n and_o the_o innumerable_a ill_a consequence_n of_o such_o a_o fundamental_a and_o overgrow_a error_n which_o certain_o must_v have_v be_v long_o since_o explode_v if_o ingenious_a man_n have_v first_o think_v and_o then_o speak_v free_o but_o the_o truth_n be_v there_o be_v many_o and_o great_a cause_n to_o the_o contrary_a as_o those_o intimate_v in_o the_o last_o paragraph_n and_o the_o mighty_a usefulness_n and_o ready_a officiousness_n of_o that_o opinion_n of_o fume_n to_o answer_v for_o all_o the_o more_o obscure_a and_o latent_fw-la cause_n of_o the_o malady_n and_o disaster_n of_o the_o brain_n and_o genus_fw-la nervosum_fw-la if_o any_o inquire_v or_o call_v for_o the_o cause_n of_o a_o vertigo_n the_o physician_n answer_v fume_n of_o epilepsy_n it_o be_v answer_v fume_n of_o scotomy_n it_o be_v fume_n of_o headache_n migraine_n coma_n caros_n lethargy_n etc._n etc._n it_o be_v fume_n of_o hysterick_n fit_n convulsion_n spasm_n cramp_n etc._n etc._n it_o be_v fume_n nay_o they_o answer_v as_o cause_n to_o all_o distillation_n catarrh_n epiphora_n or_o weep_v eye_n and_o all_o even_o ordinary_a tear_n all_o which_o they_o say_v be_v only_o these_o fume_n turn_v into_o water_n by_o the_o coldness_n of_o the_o brain_n as_o they_o be_v in_o a_o still_o or_o alembick_a so_o hot_a fume_n account_v for_o frenzy_n delirium_n rave_n etc._n etc._n so_o that_o however_o other_o head_n be_v the_o physician_n be_v be_v stuff_v therewith_o and_o all_o meteor_n of_o the_o microcosm_n upper_a region_n whether_o hot_a or_o cold_a be_v as_o those_o in_o the_o macrocosm_n form_v out_o of_o fume_n as_o he_o imagine_v thus_o you_o see_v all_o the_o opinion_n and_o hypothesise_n that_o have_v be_v concern_v the_o operation_n of_o opium_n to_o be_v most_o absurd_a and_o direct_o contrary_a to_o all_o sense_n reason_n and_o experience_n chap._n xi_o opium_n do_v not_o diminish_v or_o disable_v the_o spirit_n by_o any_o mean_n whatsoever_o have_v sufficient_o demonstrate_v that_o opium_n can_v diminish_v or_o disable_v the_o spirit_n by_o the_o cold_a quality_n of_o the_o ancient_n or_o fume_n of_o the_o modern_n and_o that_o neither_o of_o they_o have_v as_o much_o as_o any_o be_v i_o shall_v now_o add_v that_o opium_n do_v not_o diminish_v or_o disable_v the_o spirit_n by_o any_o other_o mean_n whatsoever_o i_o will_v not_o be_v mistake_v when_o i_o say_v that_o opium_n do_v not_o diminish_v or_o disable_v
watch_n and_o sentinel_n to_o discover_v and_o give_v notice_n of_o what_o be_v or_o be_v not_o good_a and_o agreeable_a to_o our_o animal_n nature_n that_o upon_o notice_n of_o what_o be_v good_a and_o agreeable_a pleasure_n comfort_n satisfaction_n etc._n etc._n be_v conceive_v otherwise_o displeasure_n discomfort_n and_o dissatisfaction_n what_o diminish_v or_o disable_v our_o spirit_n do_v we_o the_o great_a evil_n that_o can_v be_v and_o consequent_o sensation_n will_v according_a to_o its_o office_n give_v we_o such_o notice_n thereof_o as_o will_v cause_v displeasure_n etc._n etc._n otherwise_o these_o sentinel_n that_o god_n and_o nature_n have_v appoint_v for_o faithful_a notice_n will_v instead_o of_o trusty_a service_n which_o be_v the_o end_n they_o be_v make_v for_o deceive_v we_o and_o consequent_o do_v we_o mischief_n rather_o than_o good_a which_o be_v very_o profane_a if_o not_o blasphemous_a to_o assert_v as_o be_v high_o abusive_a of_o god_n goodness_n and_o wisdom_n to_o make_v thing_n in_o nature_n that_o will_v not_o only_o not_o answer_n but_o act_n quite_o contrary_a to_o their_o end_n it_o follow_v then_o that_o what_o cause_v such_o a_o mighty_a agreeable_a and_o pleasant_a sensation_n at_o stomach_n which_o be_v the_o great_a and_o most_o accurate_a judge_n of_o what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n can_v be_v destructive_a or_o disable_n of_o its_o spirit_n which_o be_v the_o most_o excellent_a and_o useful_a thing_n that_o belong_v thereto_o therefore_o opium_n which_o so_o mighty_o recommend_v itself_o to_o please_v and_o comfort_v the_o great_a judge_n that_o god_n have_v give_v to_o a_o sensible_a creature_n to_o discern_v what_o be_v good_a and_o evil_a for_o it_o can_v diminish_v or_o disable_v our_o spirit_n one_o may_v say_v what_o i_o dare_v not_o that_o the_o sensation_n at_o stomach_n may_v deceive_v we_o we_o may_v deceive_v ourselves_o and_o say_v so_o when_o that_o which_o please_v the_o stomach_n do_v not_o please_v our_o pervert_v imagination_n which_o make_v no_o argument_n let_v we_o therefore_o consider_v thing_n where_o there_o be_v no_o such_o vain_a imagination_n to_o contradict_v the_o good_a end_n of_o nature_n if_o the_o stomach_n and_o sense_n in_o a_o brute_n or_o mere_a animal_n which_o have_v no_o other_o mean_n to_o judge_n of_o what_o be_v good_a or_o evil_n for_o it_o shall_v not_o judge_v aright_o all_o the_o animal_n in_o the_o whole_a world_n will_v soon_o perish_v it_o be_v the_o vain_a opinion_n of_o man_n that_o persuade_v they_o that_o thing_n be_v cold_a when_o hot_a etc._n etc._n as_o in_o the_o case_n of_o opium_n when_o the_o sense_n true_o inform_v that_o it_o be_v hot_a if_o you_o will_v stand_v to_o your_o imagination_n and_o supposition_n for_o such_o all_o must_v be_v without_o the_o information_n of_o sense_n against_o the_o dictate_v of_o sensation_n you_o must_v inevitable_o err_v but_o one_o may_v say_v be_v the_o sense_n at_o stomach_n such_o a_o infallible_a guide_n always_o i_o believe_v it_o will_v be_v very_o hard_a to_o give_v many_o instance_n to_o the_o contrary_a and_o prove_v it_o well_o however_o if_o we_o do_v or_o may_v allow_v something_o of_o this_o kind_a to_o a_o pervert_v stomach_n at_o certain_a time_n to_o avoid_v a_o squabble_n about_o it_o it_o be_v never_o to_o be_v allow_v that_o all_o the_o stomach_n in_o the_o whole_a world_n shall_v be_v please_v with_o one_o and_o the_o same_o thing_n at_o all_o time_n and_o yet_o that_o this_o thing_n shall_v be_v so_o high_o pernicious_a to_o the_o animal_n as_o to_o diminish_v or_o disable_v its_o spirit_n then_o indeed_o it_o will_v follow_v that_o the_o most_o exquisite_a sense_n at_o stomach_n to_o discern_v what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n be_v absolute_o in_o vain_a which_o no_o man_n of_o reason_n that_o have_v any_o apprehension_n of_o the_o wisdom_n of_o god_n and_o nature_n can_v assert_v 3._o what_o be_v more_o notorious_a than_o that_o pleasure_n or_o be_v please_v raise_v and_o displeasure_n or_o be_v grieve_v depress_n the_o spirit_n be_v not_o all_o people_n pleasant_a gay_a and_o good_a humour_a brisk_a prompt_a etc._n etc._n when_o please_v do_v not_o man_n travel_v or_o labour_n with_o more_o ease_n in_o pleasant_a company_n etc._n etc._n but_o of_o these_o matter_n and_o the_o reason_n thereof_o more_o in_o the_o follow_a chapter_n 4._o how_o can_v opium_n that_o revive_v people_n when_o they_o be_v so_o dispirited_a that_o they_o be_v even_o almost_o die_v as_o when_o opium_n be_v want_v by_o such_o as_o use_v to_o take_v it_o in_o deliquiâ—ms_n and_o agony_n from_o paiâ—_n etc._n etc._n diminish_v or_o disable_v the_o spirit_n it_o be_v plain_a contradiction_n to_o say_v that_o it_o shall_v next_o to_o opium_n nothing_o revive_v people_n in_o such_o case_n better_o than_o wine_n and_o those_o thing_n that_o produce_v the_o same_o or_o like_a effect_n have_v like_o nature_n and_o who_o can_v say_v that_o wine_n that_o be_v make_v to_o glad_a the_o heart_n of_o man_n diminish_v or_o disable_v the_o spirit_n or_o that_o opium_n which_o produce_v all_o the_o sprightly_a enliven_a and_o encourage_v effect_n of_o generous_a wine_n in_o a_o more_o eminent_a manner_n than_o wine_n and_o in_o the_o 10000th_o part_n of_o its_o quantity_n and_o for_o a_o long_a time_n than_o wine_n cause_v they_o shall_v diminish_v or_o disable_v the_o spirit_n for_o instance_n wine_n and_o opium_n in_o a_o due_a quantity_n but_o opium_n in_o a_o far_o less_o quantity_n as_o be_v say_v cause_v a_o pleasant_a gay_a and_o good_a humour_n courage_n bravery_n magnanimity_n promptitude_n in_o business_n expediteness_n in_o management_n serenity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n fatigue_n etc._n etc._n both_o take_v away_o sadness_n grief_n melancholy_n fear_v depression_n of_o spirit_n etc._n etc._n both_o cause_n promptitude_n to_o venery_n sine_fw-la cerere_fw-la &_o baccho_fw-la friget_fw-la venus_n so_o wine_n and_o opium_n prevent_v and_o cure_v cold_a open_v the_o pore_n promote_v perspiration_n and_o sweat_n especial_o the_o follow_a morning_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v of_o opium_n and_o be_v notorious_a as_o to_o wine_n both_o cause_n sleep_n and_o take_v away_o the_o sense_n of_o pain_n and_o require_v a_o great_a dose_n than_o ordinary_a in_o proportion_n to_o the_o pain_n both_o take_v off_o shivering_n from_o fear_n cold_a or_o ague_n fit_n and_o cause_n mirth_n contentation_n and_o acquiescence_n dryness_n of_o the_o mouth_n thirst_v a_o sense_n of_o heat_n within_o we_o a_o dream_v condition_n pleasant_a dream_n if_o the_o quantity_n of_o wine_n be_v not_o grievous_a by_o its_o heat_n load_n etc._n etc._n nocturnal_a pollution_n and_o in_o some_o constitution_n both_o cause_n vigilancy_n but_o wine_n and_o opium_n cause_v that_o more_o rare_o than_o sleep_n both_o stop_n and_o cause_n vomit_v if_o they_o stay_v too_o long_o at_o stomach_n both_o moderate_a hunger_n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d and_o be_v good_a in_o a_o canine_a appetite_n both_o cause_n swim_v in_o the_o head_n etc._n etc._n so_o both_o in_o a_o excessive_a do_v do_v cause_n at_o first_o mirth_n and_o afterward_o a_o kind_n of_o drunken_a soper_n in_o some_o in_o other_o fury_n or_o madness_n sardonick_a laughter_n and_o weight_n at_o stomach_n vomit_n hiccough_n great_a heat_n at_o stomach_n debility_n and_o laxity_n of_o all_o part_n falter_v of_o the_o tongue_n scotomy_n and_o darkness_n of_o the_o eye_n vertigo_n laxity_n of_o the_o cornea_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la deadness_n of_o the_o eye_n to_o the_o view_n loss_n of_o memory_n venereal_a fury_n a_o high_a colour_n profuse_a sweat_v purge_v sometime_o alienation_n of_o the_o mind_n loss_n of_o memory_n and_o last_o great_a or_o lesser_a effect_n according_a to_o the_o do_v constitution_n etc._n etc._n so_o a_o long_a and_o lavish_a use_n of_o both_o cause_n a_o dull_a and_o moapish_a disposition_n dropsy_n fall_v of_o humour_n upon_o weaken_v part_n a_o sleepy_a disposition_n want_v of_o appetite_n weakness_n of_o digestion_n aptitude_n to_o sterility_n and_o abortion_n early_a decrepiteness_n stoop_v in_o the_o back_n tremble_v of_o the_o hand_n weakness_n of_o memory_n shortness_n of_o life_n difficulty_n and_o danger_n in_o sudden_o leave_v they_o off_o revive_v such_o as_o sink_v for_o want_n of_o either_o and_o supply_v the_o want_n of_o each_o other_o how_o can_v any_o have_v the_o face_n to_o say_v that_o a_o thing_n which_o agree_v so_o with_o generous_a wine_n in_o effect_n can_v be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n the_o mischief_n of_o excessive_a dose_n and_o lavish_a use_n of_o either_o be_v no_o argument_n against_o their_o inspirit_a nature_n if_o it_o be_v than_o wine_n be_v no_o cordial_n though_o make_v to_o glad_a the_o heart_n
proclaim_v their_o ignorance_n and_o glory_v in_o their_o great_a shame_n and_o disgrace_n of_o mankind_n that_o humane_a species_n shall_v have_v any_o such_o unthinking_a brute_n in_o it_o iv_o we_o must_v not_o use_v acid_n in_o the_o preparation_n thereof_o 1._o because_o be_v in_o their_o nature_n opposite_a to_o volatile_a salt_n it_o can_v be_v do_v without_o injury_n to_o the_o sal-volatile-oleosum_a of_o opium_n 2._o because_o they_o can_v so_o well_o agree_v with_o the_o oily_a part_n of_o it_o yet_o be_v they_o not_o so_o much_o to_o be_v blame_v as_o extract_n make_v in_o spirit_n of_o wine_n or_o sulphureous_a menstruum_n because_o acid_a menstruum_n leave_v the_o rosin_n behind_o they_o untouched_a or_o not_o extract_v v._o a_o salino-volatile_a menstruum_fw-la as_o spirit_n of_o sal_fw-la ammoniac_a of_o urine_n etc._n etc._n be_v not_o so_o proper_a 1._o it_o may_v render_v the_o sal-volatile-oleosum_a of_o opium_n too_o acrimonious_a 2._o because_o by_o its_o volatility_n acrimony_n etc._n etc._n it_o may_v cause_v too_o great_a a_o stir_n in_o the_o blood_n etc._n etc._n and_o so_o oppose_v or_o hinder_v sleep_n which_o be_v one_o of_o the_o most_o happy_a and_o useful_a effect_n of_o opium_n or_o it_o be_v sal-volatile-oleosum_a 3._o because_o it_o may_v have_v undue_a effect_n by_o alter_v its_o general_a disposition_n nay_o vi_o we_o be_v not_o to_o use_v a_o lixivial_a menstruum_fw-la though_o so_o much_o cry_v up_o 1._o because_o it_o extract_v the_o resinous_a part_n which_o experto_fw-la crede_fw-la roberto_n i_o have_v find_v to_o be_v pernicious_a upon_o that_o account_n like_o extract_n in_o spirit_n of_o wine_n unless_o great_a care_n be_v take_v to_o separate_v those_o part_n which_o be_v not_o easy_o do_v by_o filtration_n etc._n etc._n 2._o because_o be_v very_o apt_a to_o join_v with_o the_o oily_a part_n and_o quite_o to_o destroy_v their_o nature_n by_o convert_v it_o into_o a_o kind_n of_o sapo_n it_o may_v deal_v so_o with_o some_o of_o the_o oily_a part_n of_o the_o sal-volatile-oleosum_a of_o opium_n 3._o because_o there_o be_v no_o need_n to_o run_v any_o of_o these_o hazard_n since_o the_o sal-volatile-oleosum_a may_v be_v as_o i_o shall_v show_v easy_o extract_v in_o its_o purity_n without_o those_o trouble_n and_o danger_n 4._o because_o any_o tincture_n make_v thus_o be_v apt_a to_o let_v go_v the_o rosin_n at_o stomach_n if_o it_o be_v dilute_v with_o aqueous_a moisture_n take_v before_o with_o it_o or_o after_o it_o which_o so_o be_v let_v go_v coalesces_fw-la and_o do_v mischief_n vii_o the_o use_n of_o fire_n any_o way_n beside_o that_o of_o its_o torrefaction_n be_v much_o to_o be_v suspect_v 1._o because_o the_o sal-volatile-oleosum_a may_v be_v in_o some_o measure_n thereby_o evaporate_v or_o 2._o an_fw-mi empyreum_fw-la contract_v and_o 3._o the_o rosin_n as_o be_v say_v of_o its_o torrefaction_n grow_v the_o more_o in_o proportion_n if_o any_o of_o the_o sal-volatile-oleosum_a or_o but_o the_o phlegm_n be_v by_o that_o mean_n evaporate_v and_o the_o remainder_n keep_v for_o use_v and_o particular_o viii_o the_o distillation_n thereof_o may_v cause_v mighty_a alteration_n in_o its_o property_n strength_n etc._n etc._n we_o must_v therefore_o avoid_v all_o these_o way_n of_o prepare_v it_o and_o yet_o must_v we_o 1._o separate_a the_o sal-volatile-oleosum_a of_o opium_n from_o all_o its_o rosin_n earth_n filth_n and_o dross_n 2._o no_o way_n weaken_v it_o alter_v it_o or_o add_v new_a quality_n thereto_o but_o preserve_v this_o most_o noble_a and_o inestimable_a medicament_n in_o its_o purity_n and_o sincerity_n to_o this_o end_n rain_n water_v distil_v use_v cold_a answer_v all_o intent_n for_o 1._o it_o ready_o imbibe_v the_o sal-volatile-oleosum_a of_o opium_n without_o fire_n heat_v lixivial_a salt_n as_o salt_n of_o tartar_n etc._n etc._n 2._o it_o imbibe_v none_o of_o the_o rosin_n of_o the_o opium_n but_o let_v it_o all_o subside_n together_o with_o the_o earthy_a and_o drossy_a part_n separate_v the_o light_a filth_n if_o there_o be_v any_o to_o the_o surface_n 3._o it_o no_o way_n weaken_v alter_v or_o add_v any_o new_a quality_n to_o the_o sal-volatile-oleosum_a 4._o whatever_o cold_a water_n dissolve_v which_o be_v the_o general_n drink_v or_o menstruum_fw-la appoint_v by_o the_o alwise_a creater_n for_o the_o dissolution_n of_o all_o thing_n take_v into_o the_o stomach_n of_o animal_n be_v easy_o dissolve_v at_o stomach_n by_o its_o more_o powerful_a and_o agreeable_a menstruum_fw-la and_o not_o only_o so_o but_z 5._o water_n itself_o be_v a_o mighty_a stomachick_n and_o causer_n of_o digestion_n as_o hypocrates_n positive_o declare_v l._n 6._o epidem_fw-la sect._n 4._o but_o there_o be_v no_o need_n of_o quote_v hypocrates_n in_o so_o notorious_a a_o thing_n daily_a experience_n tell_v we_o the_o same_o do_v not_o all_o animal_n by_o its_o help_n digest_v their_o food_n do_v not_o all_o mineral_n water_n scarce_o any_o except_v create_v a_o appetite_n and_o cause_n digestion_n even_o when_o no_o such_o effect_n can_v be_v attribute_v to_o the_o mineral_n they_o contain_v than_o which_o they_o do_v also_o as_o may_v be_v very_o easy_o prove_v more_o good_a general_o speak_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d for_o which_o and_o many_o more_o reason_n it_o be_v great_a neglect_n and_o folly_n that_o it_o be_v not_o more_o use_v for_o extract_n etc._n etc._n for_o then_o they_o ready_o dissolve_v at_o stomach_n and_o thereby_o 〈◊〉_d and_o speedy_o take_v effect_n give_v it_o the_o least_o 〈◊〉_d and_o disturbance_n that_o may_v be_v as_o be_v experimental_o find_v in_o that_o of_o aloe_n scammony_n briony_n 〈◊〉_d agariâ—_n 〈◊〉_d coloquintida_n sena_n and_o what_o not_o unless_o the_o virtue_n lie_v in_o the_o resinous_a parâ—s_n for_o then_o sulphureous_a or_o lixivial_a menstruum_n be_v convenient_a how_o inconvenient_a be_v they_o then_o when_o the_o evil_a or_o mischief_n lie_v therein_o as_o in_o our_o case_n 6._o it_o be_v not_o to_o be_v doubt_v but_o water_n general_o imbibe_v what_o be_v best_a and_o most_o agreeable_a to_o our_o body_n it_o be_v the_o general_n menstruum_fw-la appoint_v by_o wisdom_n itself_o for_o that_o use_v and_o to_o be_v the_o vehicle_n of_o what_o be_v best_a in_o all_o our_o food_n etc._n etc._n to_o the_o blood_n however_o there_o can_v be_v no_o doubt_n of_o what_o main_o concern_v we_o at_o present_a its_o most_o ready_a dissolve_v our_o panacea_fw-la in_o the_o stomach_n that_o do_v it_o out_o of_o it_o when_o cold_a without_o the_o convenient_a digestive_a heat_n and_o powerful_a menstruum_fw-la that_o it_o find_v there_o therefore_o take_v of_o distil_a rain-water_n 24_o ounce_n of_o choice_a opium_n slice_v thin_a 8_o ounce_n put_v they_o together_o in_o a_o strong_a glass_n vessel_n of_o bottle-metal_n that_o contain_v about_o 3_o piâ—ts_n let_v it_o be_v of_o a_o tall_a figure_n with_o a_o mouth_n that_o convenient_o receive_v a_o cork_n a_o large_a glass_n bottle_n may_v serve_v the_o turn_n cork_n it_o so_o as_o the_o cork_n may_v be_v easy_o take_v out_o shake_v it_o 3_o or_o 4_o time_n a_o day_n for_o 6_o day_n and_o keep_a it_o in_o a_o place_n free_a from_o frost_n or_o any_o very_a sensible_a degree_n of_o heat_n which_o be_v perform_v lie_v the_o vessel_n side-long_a for_o 24_o hour_n long_o and_o afterward_o decant_v and_o filter_n your_o tincture_n which_o will_v be_v of_o a_o ruby_n colour_n and_o put_v it_o into_o a_o glass_n bottle_n of_o such_o a_o bigness_n as_o that_o it_o may_v fill_v it_o within_o a_o small_a matter_n of_o the_o cork_n and_o so_o let_v it_o stand_v for_o 3_o or_o 4_o day_n then_o poâ—r_v off_o some_o of_o the_o surface_n of_o it_o and_o instead_o thereof_o put_v sweet_a oil_n thereon_o let_v the_o vessel_n have_v a_o convenient_a dust_n or_o pipe_n in_o the_o side_n thereof_o to_o empty_v it_o out_o upon_o occasion_n this_o i_o call_v the_o liquid_a panacea_fw-la of_o opium_n to_o the_o faeces_fw-la add_v a_o pint_n of_o cold_a distil_a water_n shake_v the_o vessel_n as_o before_o 3_o or_o 4_o time_n in_o the_o day_n let_v it_o stand_v on_o it_o 24_o hour_n and_o in_o the_o morning_n decant_v it_o into_o another_o vessel_n repeat_v the_o same_o quantity_n of_o distil_a rain-water_n till_o the_o opium_n no_o long_o tinge_v it_o or_o very_o inconsiderable_o in_o 24_o hour_n at_o last_o you_o may_v use_v water_n keep_v hot_a by_o a_o fire_n &c_n &c_n the_o better_a to_o extract_v the_o remain_v sal-volatile-oleosum_a evaporate_v all_o these_o last_o water_n in_o balneo_fw-la to_o the_o consistence_n of_o a_o extract_n this_o i_o call_v the_o solid_a panacea_fw-la of_o opium_n god_n and_o nature_n act_v by_o simple_a mean_n and_o nothing_o in_o imitation_n of_o they_o be_v more_o commendable_a in_o a_o medicament_n than_o simplicity_n therefore_o i_o shall_v add_v nothing_o to_o the_o panacea_n but_o whole_o
it_o be_v best_o like_v and_o most_o suitable_a to_o people_n mind_n palate_n etc._n etc._n ii_o the_o do_v moderate_a except_o it_o be_v 1._o where_o some_o by_o accident_n require_v otherwise_o as_o pain_n looseness_n vomit_n and_o to_o titillate_v the_o venereal_a membrane_n because_o remote_a which_o see_v in_o the_o respective_a chapter_n of_o the_o use_n of_o opiate_n in_o those_o case_n 2._o where_o the_o general_a rule_n direct_v otherwise_o as_o in_o the_o soft_a flesh_a people_n child_n woman_n etc._n etc._n where_o the_o do_v must_v be_v less_o iii_o the_o vehicle_n must_v be_v the_o same_o as_o be_v direct_v to_o compose_v but_o in_o old_a people_n it_o be_v observe_v that_o smooth_a spirituous_a thing_n as_o good_a ale_n etc._n etc._n conduce_v very_o much_o to_o cause_v sleep_n because_o sulphur_n do_v qualifie-the_a volatile_a salt_n of_o the_o opium_n as_o be_v show_v iv_o the_o time_n in_o general_n be_v at_o the_o due_a distance_n before_o bedtime_n that_o be_v direct_v in_o the_o general_a rule_n but_o opiate_n may_v be_v give_v at_o any_o time_n when_o the_o case_n require_v as_o in_o the_o smallpox_n about_o 12_o 1_o or_o 2_o in_o the_o afternoon_n according_a as_o the_o â—tions_n which_o happen_v in_o the_o afternoon_n or_o towards_o the_o evening_n do_v seize_v they_o and_o in_o ague_n at_o the_o due_a distance_n before_o the_o paroxysm_n invade_v they_o 〈◊〉_d that_o the_o operation_n thereof_o may_v be_v fall_n and_o complete_a before_o the_o time_n that_o the_o fit_n be_v to_o begin_v and_o so_o in_o all_o other_o câ—ses_n of_o the_o like_a â—ind_n v._o the_o regimen_n in_o this_o 〈◊〉_d 〈◊〉_d 〈◊〉_d twosold_a aspect_n 1._o to_o promote_v 〈◊〉_d 2._o to_o compose_v and_o quiet_a motion_n 〈◊〉_d â—tions_n of_o the_o spirit_n 〈◊〉_d etc._n etc._n 〈◊〉_d 〈◊〉_d quiet_v be_v the_o two_o 〈◊〉_d 〈◊〉_d as_o to_o the_o first_o the_o regimen_n must_v be_v the_o same_o as_o be_v direct_v in_o the_o chapter_n of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o relax_v but_o as_o to_o compose_v and_o quiet_v the_o spirit_n i_o shall_v add_v somewhat_o though_o relaxer_n be_v general_o good_a for_o this_o purpose_n unless_o join_v with_o some_o agitate_v accident_n as_o heat_n or_o the_o like_a 1._o as_o to_o diet_n it_o shall_v consist_v of_o cool_a incrassate_a inviscate_a thing_n that_o be_v not_o aromatic_a acid_a or_o saline_a such_o be_v milk-meat_n emulsion_n almond_n milks_n chicken_n broth_n with_o cool_a herb_n water-gruel_n fresh_a and_o young_a soft_a flesh_n lettuce_n purstane_n spinage_n herb_n mercury_n mallow_n and_o such_o like_a mucilage_n as_o of_o quince_n fleabane_n etc._n etc._n the_o drink_n may_v be_v milk_n and_o water_n whey_n or_o such_o unfermented_a liquor_n or_o smooth_a small_a beer_n not_o too_o old_a for_o all_o stale_a drink_n be_v naught_o water_n where_o it_o agree_v etc._n etc._n 2._o rest_v of_o body_n and_o spirit_n must_v be_v contrive_v by_o all_o mean_n as_o by_o lean_v lie_a or_o sit_v still_o without_o any_o motion_n after_o it_o be_v take_v till_o bedtime_n and_o therefore_o let_v the_o person_n if_o the_o season_n permit_v be_v as_o much_o undress_v as_o may_v be_v in_o a_o loose_a garment_n or_o morning-gown_n all_o that_o time_n and_o be_v help_v off_o with_o his_o clothes_n that_o he_o may_v not_o agitate_v his_o body_n when_o sleepy_a and_o not_o before_o let_v he_o go_v into_o a_o cold_a bed_n in_o summer_n and_o but_o a_o little_a warm_v in_o winter_n and_o only_o have_v what_o bedclothe_n suffice_v and_o please_v he_o best_o and_o then_o lie_v absolute_o still_o without_o noise_n light_z or_o fire_n in_o the_o room_n 3._o rest_v and_o tranquillity_n of_o mind_n be_v very_o necessary_a which_o shall_v be_v not_o only_o free_a from_o grievous_a passion_n but_o from_o all_o excess_n of_o joyous_a one_o which_o too_o much_o agitate_v the_o spirit_n 4._o the_o air_n shall_v be_v moist_a and_o moderate_a and_o if_o not_o such_o by_o the_o wether_n render_v so_o by_o art_n especial_o in_o fever_n 5._o all_o evacuation_n shall_v be_v make_v that_o may_v any_o way_n disturb_v his_o sleep_n before_o he_o betake_v himself_o to_o it_o nor_o shall_v the_o stomach_n be_v over-full_a or_o empty_a lest_o any_o grievance_n may_v be_v thereby_o create_v 6._o emollient_a tepid_a bath_n fomentation_n feetwash_n etc._n etc._n do_v fine_o dispose_v people_n to_o sleep_n but_o take_v care_n they_o be_v not_o too_o hot_a for_o heat_n cause_v a_o stir_n of_o blood_n and_o spirit_n which_o be_v a_o enemy_n to_o sleep_n 1._o note_v that_o long_o sleep_v after_o great_a fatigue_n or_o long_o watch_v ought_v not_o to_o be_v very_o frightful_a if_o the_o do_v be_v moderate_a and_o that_o the_o person_n take_v sustenance_n 2._o note_v that_o old_a or_o dry_a person_n or_o such_o as_o be_v very_o unapt_a to_o sleep_v after_o opiate_n be_v often_o cause_v to_o sleep_v by_o smooth_a wine_n ale_z cowslip_n wine_n or_o the_o like_a because_o the_o gentle_a oiliness_n of_o such_o liquor_n do_v correct_v the_o acrimony_n of_o their_o volatile_a salt_n and_o at_o the_o same_o time_n cause_n a_o sense_n of_o pleasure_n which_o relax_n and_o cause_n sleep_v it_o have_v be_v observe_v that_o even_o ambergrise_v and_o musk_n which_o exagitate_v the_o blood_n and_o spirit_n cause_v old_a man_n to_o sleep_n which_o happen_v by_o their_o fine_a sulphur_n ready_o fasten_v upon_o the_o acrimonious_a volatile_a salt_n as_o spirit_n of_o wine_n do_v upon_o sal_fw-la ammoniac_a which_o be_v mix_v do_v soon_o coagulate_v therefore_o i_o be_o apt_a to_o think_v that_o camphire_n will_v be_v of_o excellent_a use_n to_o correct_v the_o opium_n and_o the_o volatile_a salt_n of_o the_o body_n in_o such_o case_n because_o it_o be_v experimental_o certain_a that_o it_o correct_v the_o acrimony_n of_o urine_n of_o semen_n virile_a cantharides_n etc._n etc._n 3._o note_v that_o the_o dry_a the_o body_n be_v the_o more_o unapt_a be_v opiate_n to_o cause_n sleep_n therefore_o dry_a body_n as_o of_o old_a man_n hectical_a person_n etc._n etc._n shall_v be_v well_o moisten_v by_o incrassative_a moistener_n as_o emulsion_n and_o such_o thing_n as_o be_v above_o mention_v and_o order_v in_o the_o chapter_n of_o the_o relax_a use_n of_o opiate_n from_o what_o be_v say_v i_o do_v conclude_v that_o opiate_n do_v cause_n sleep_v very_o ready_o where_o the_o oily_a part_n abound_v and_o that_o thing_n that_o have_v a_o fine_a oleous_a sulphur_n be_v very_o good_a corrector_n of_o it_o where_o acrimonious_a volatile_a salt_n abound_v in_o order_n to_o cause_n sleep_n and_o that_o hence_o it_o be_v that_o some_o ancient_a people_n will_v often_o sleep_v better_o by_o the_o use_n of_o the_o aforementioned_a smooth_a ferment_v sulphureous_a liquor_n than_o by_o the_o use_n of_o opium_n from_o all_o which_o it_o appear_v that_o sleep_n be_v not_o such_o a_o property_n of_o opium_n as_o people_n make_v it_o to_o be_v because_o that_o beside_o relax_v sleep_v also_o require_v a_o great_a rest_n of_o the_o spirit_n and_o the_o sensitive_a soul_n it_o seem_v very_o probable_a from_o the_o premise_n that_o anodyne_n sulphur_n of_o vitriol_n will_v be_v excellent_a to_o cause_v old_a man_n to_o sleep_n for_o it_o doubtless_o cause_n sleep_v only_o by_o obtund_v and_o qualify_a our_o volatile_a salt_n as_o white_a 〈◊〉_d and_o other_o balsamicks_n will_v often_o do_v chap._n xxxvi_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o stop_v flux_n it_o palliate_v moderate_v and_o stop_v flux_n 1._o by_o take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o cause_n contraction_n to_o squeeze_v they_o out_o and_o promote_v their_o motion_n 2._o because_o it_o compose_v and_o still_v the_o motion_n of_o humour_n by_o the_o relaxation_n and_o the_o sleep_n that_o it_o cause_n which_o quiet_v motion_n 3._o because_o thereby_o and_o by_o its_o combine_a agreeableness_n and_o texture_n it_o congregate_n the_o disgregated_a humour_n 4._o because_o the_o relaxation_n suspend_v the_o humour_n 5._o because_o it_o discuss_n ill_a humour_n 6._o because_o the_o pore_n be_v open_v by_o the_o relaxation_n the_o humour_n that_o cause_v the_o flux_n be_v gradual_o perspire_v by_o that_o most_o natural_a and_o universal_a sort_n of_o evacuation_n for_o it_o be_v plain_a reason_n and_o common_a observation_n that_o a_o plentiful_a evacuation_n at_o pore_n stop_v flux_n per_fw-la anum_fw-la etc._n etc._n and_o if_o it_o continue_v perfect_o cure_v they_o ☞_o hence_o it_o be_v that_o the_o use_v of_o opiate_n continue_v do_v happy_o not_o only_o palliate_v but_o perfect_o cure_v diarrheas_n dysentery_n defluxion_n catarrh_n etc._n etc._n it_o therefore_o follow_v that_o it_o be_v of_o great_a use_n 1._o to_o palliate_v moderate_a or_o cure_v all_o flux_n that_o proceed_v from_o irritation_n of_o humour_n as_o vomit_n