while_o these_o muscle_n be_v contract_v for_o inspiration_n and_o another_o while_n for_o expiration_n in_o the_o mean_a while_o the_o opposite_a muscle_n have_v a_o pause_n and_o be_v move_v by_o turn_n that_o they_o mutual_o give_v place_n to_o themselves_o successive_o from_o all_o this_o in_o the_o first_o place_n it_o be_v clear_a which_o likewise_o in_o another_o place_n we_o have_v abundant_o declare_v that_o the_o animal_n spirit_n for_o the_o exercise_v the_o contractive_a motion_n of_o the_o muscle_n leap_v from_o the_o tendon_n into_o the_o fleshy_a fibres_fw-fr and_o afterward_o for_o their_o relaxation_n they_o recede_v out_o of_o these_o into_o those_o moreover_o whereas_o the_o mutual_a function_n be_v twofold_a viz._n spontaneous_a and_o mere_o natural_a function_n in_o the_o animal_n function_n we_o have_v before_o show_v in_o the_o former_a that_o the_o spirit_n be_v bring_v from_o the_o tendon_n into_o the_o fleshy_a fibres_fw-fr by_o approach_n according_a to_o the_o command_n of_o appetite_n and_o to_o remain_v within_o during_o the_o action_n till_o they_o be_v dismiss_v by_o its_o will_n and_o afterward_o return_v into_o the_o tendon_n till_o they_o be_v again_o command_v forth_o insomuch_o that_o the_o time_n of_o their_o motion_n and_o rest_n be_v unequal_a and_o uncertain_a and_o various_o determine_v at_o our_o pleasure_n but_o it_o be_v far_o otherwise_o in_o the_o natural_a function_n natural_a and_o natural_a because_o the_o animal_n spirit_n be_v carry_v out_o from_o the_o tendon_n into_o the_o flesh_n by_o perpetual_a turn_n or_o constant_a reciprocation_n and_o a_o short_a contraction_n be_v make_v present_o leap_v back_o from_o the_o flesh_n into_o the_o tendon_n and_o so_o alternate_o after_o which_o manner_n the_o heart_n itself_o the_o organ_n of_o the_o trachea_n and_o breathe_v also_o the_o fleshy_a fibres_fw-fr of_o the_o stomach_n and_o gut_n unless_o they_o be_v otherwise_o limit_v by_o reason_n of_o their_o object_n be_v drive_v on_o by_o their_o constant_a systole_n and_o diastole_n it_o will_v be_v needless_a to_o repeat_v here_o what_o we_o have_v already_o observe_v in_o another_o place_n touch_v these_o two_o kind_n of_o motion_n cerebellum_fw-la the_o motion_n of_o the_o former_a sort_n arise_v from_o the_o brain_n the_o other_o from_o the_o cerebellum_fw-la viz._n that_o the_o animal_n spirit_n of_o the_o spontaneous_a move_a function_n be_v altogether_o or_o chief_o dispense_v from_o the_o brain_n and_o the_o other_o causer_n of_o the_o mere_o natural_a function_n be_v dispense_v from_o the_o cerebellum_fw-la moreover_o also_o as_o the_o plenty_n of_o both_o sort_n of_o spirit_n so_o the_o very_a instinct_n of_o beginning_n those_o action_n have_v their_o conveyance_n through_o the_o nerve_n notwithstanding_o here_o arise_v a_o doubt_n to_o what_o kind_n of_o move_a function_n be_v it_o be_v a_o quaere_fw-la of_o what_o kind_n the_o action_n of_o breathe_v be_v viz._n whether_o spontaneous_a or_o mere_o natural_a the_o action_n of_o breathe_v aught_o to_o be_v refer_v also_o of_o what_o original_n viz._n whether_o of_o the_o brain_n or_o cerebellum_fw-la the_o animal_n spirit_n appoint_v to_o that_o employment_n be_v it_o be_v manifest_a enough_o that_o this_o function_n be_v in_o a_o sort_n partaker_n of_o a_o spontaneous_a motion_n because_o it_o be_v in_o our_o power_n one_o while_n to_o shorten_v its_o exercise_n at_o other_o time_n to_o prolong_v and_o otherwise_o diverse_o to_o alter_v they_o yea_o sometime_o a_o little_a to_o restrain_v they_o moreover_o the_o nerve_n belong_v to_o its_o chief_a move_a organ_n viz._n the_o diaphragma_n and_o muscle_n of_o the_o breast_n spring_v from_o the_o nerve_n of_o the_o arm_n and_o loin_n do_v owe_v their_o descent_n to_o the_o brain_n and_o do_v plain_o acknowledge_v the_o spirit_n they_o contain_v be_v chief_o ordain_v for_o voluntary_a motion_n but_o moreover_o on_o the_o contrary_a this_o function_n be_v so_o far_o natural_a that_o its_o organ_n do_v reciprocate_v the_o constant_a change_n of_o systole_n and_o diastole_n in_o sleep_n without_o our_o notice_n and_o while_o we_o wake_v we_o not_o perceive_v it_o moreover_o although_o we_o can_v for_o some_o little_a time_n stop_v its_o exercise_n or_o at_o our_o pleasure_n vary_v it_o yet_o we_o deny_v it_o to_o be_v altogether_o or_o long_o suspend_v beside_o although_o the_o nerve_n appoint_v to_o the_o muscle_n of_o the_o breast_n and_o diaphragma_n proceed_v from_o the_o spinal_a nerve_n yet_o these_o latter_a come_n from_o the_o branch_n belong_v to_o the_o arm_n communicate_v in_o their_o progress_n with_o the_o slip_n of_o the_o intercostal_a nerve_n moreover_o all_o the_o other_o nerve_n which_o belong_v to_o the_o cerebellum_fw-la arise_v from_o these_o which_o be_v spread_v about_o through_o the_o trachea_n and_o lung_n from_o these_o it_o plain_o follow_v act_n it_o be_v conclude_v to_o be_v a_o mix_a act_n that_o the_o power_n of_o breathe_v be_v as_o it_o be_v a_o mix_a action_n and_o do_v participate_v of_o either_o move_a function_n viz._n as_o well_o of_o the_o spontaneous_a as_o natural_a and_o that_o the_o spirit_n and_o nerve_n of_o either_o province_n be_v employ_v in_o this_o duty_n which_o proceed_v as_o well_o from_o the_o brain_n as_o from_o the_o cerebellum_fw-la and_o true_o so_o it_o ought_v to_o come_v to_o pass_v according_a to_o the_o animal_n government_n for_o although_o some_o action_n of_o breathe_v necessary_a for_o the_o preserve_a life_n aught_o to_o be_v constant_a and_o perpetual_a there_o be_v yet_o many_o other_o motion_n of_o the_o breast_n and_o lung_n only_o occasional_a and_o to_o be_v perform_v at_o our_o pleasure_n as_o may_v be_v discern_v in_o laugh_v crying_z singing_z hollow_v whistle_a and_o other_o singular_a office_n of_o the_o lung_n and_o windpipe_n in_o which_o work_v that_o they_o may_v be_v do_v strong_o the_o muscle_n conspire_v together_o and_o endeavour_v joint_o as_o in_o violent_a labour_n and_o exercise_n of_o the_o whole_a body_n by_o which_o the_o blood_n be_v stir_v up_o do_v want_v the_o great_a ventilution_n the_o arm_n be_v vehement_o move_v also_o do_v force_n the_o muscle_n of_o the_o breast_n and_o other_o pneumonic_a organ_n into_o more_o speedy_a motion_n for_o a_o more_o frequent_a breathe_n and_o true_o for_o joint_a labour_n of_o this_o sort_n of_o the_o arm_n and_o diaphragma_n the_o nerve_n serve_v this_o motion_n proceed_v from_o the_o nervous_a branch_n of_o they_o moreover_o it_o be_v provide_v for_o this_o purpose_n lest_o the_o exercise_n of_o the_o body_n may_v enfeeble_v at_o any_o time_n the_o strength_n of_o the_o lung_n or_o exceed_v the_o order_n of_o breathe_v for_o when_o its_o organ_n labour_v more_o difficult_o or_o begin_v to_o be_v weary_a the_o nerve_n of_o the_o diaphragma_n do_v warn_v the_o other_o nerve_n of_o the_o arm_n pluck_v they_o and_o as_o it_o be_v admonish_v of_o their_o duty_n to_o desist_v from_o a_o over_o intense_a motion_n for_o whereas_o the_o function_n of_o breathe_v be_v ordain_v for_o many_o use_n voluntary_a the_o nerve_n of_o the_o lung_n some_o ruler_n of_o the_o natural_a motion_n and_o other_o of_o the_o voluntary_a whereof_o some_o be_v mere_o natural_a and_o other_o spontaneous_a or_o violent_a therefore_o the_o spirit_n and_o the_o nerve_n which_o proceed_v and_o have_v their_o government_n as_o well_o from_o the_o brain_n as_o from_o the_o cerebellum_fw-la aught_o to_o be_v join_v together_o and_o to_o afford_v their_o social_a endeavour_n yet_o on_o that_o condition_n and_o as_o it_o be_v by_o mutual_a agreement_n that_o one_o give_v place_n to_o the_o other_o by_o turn_n for_o the_o discharge_n all_o work_n chief_o necessary_a or_o convenient_a and_o do_v mutual_o obey_v from_o the_o pneumonic_a nerve_n the_o instinct_n of_o ordinary_a breathe_n or_o mere_o vital_a begin_v and_o be_v present_o communicate_v to_o the_o nerve_n of_o the_o diaphragma_n and_o from_o thence_o to_o all_o of_o the_o thorax_n office_n both_o do_v alternate_o obey_v one_o the_o other_o and_o agree_v in_o their_o office_n so_o that_o present_o all_o the_o move_a part_n agree_v together_o in_o the_o action_n and_o cause_v the_o systole_n and_o diastole_n of_o the_o breast_n in_o such_o sort_n as_o be_v require_v to_o the_o present_a state_n of_o the_o blood_n notwithstanding_o on_o the_o contrary_a as_o to_o other_o action_n of_o breathe_v whether_o spontaneous_a or_o violent_a it_o seem_v to_o have_v they_o also_o viz._n the_o instinct_n or_o first_o force_n of_o these_o beginning_z one_o while_n from_o these_o muscle_n another_o while_n from_o they_o be_v present_o communicate_v to_o all_o the_o other_o organ_n so_o that_o it_o be_v call_v upon_o by_o a_o work_a consort_n of_o all_o together_o soon_o than_o the_o twinkle_n of_o the_o eye_n for_o the_o perform_v the_o design_a act_n of_o breathe_v what_o we_o have_v hitherto_o declare_v about_o the_o organ_n of_o breathe_v
administer_v both_o a_o dropace_n and_o vesicatory_a also_o by_o apply_v still_o the_o same_o plaster_n the_o scarf-skin_n be_v blister_a and_o take_v off_o and_o the_o place_n be_v red_a and_o ulcerate_v and_o only_o wipe_v it_o once_o or_o twice_o in_o a_o day_n and_o put_v it_o on_o again_o they_o cause_v the_o little_a ulcer_n raise_v by_o the_o vesicatory_a to_o flow_v at_o pleasure_n yea_o sometime_o above_o a_o month_n and_o to_o throw_v off_o a_o plentiful_a ichor_n other_o enclose_v cantharides_n bruise_v and_o sprinkle_v with_o vinegar_n in_o silk_n and_o apply_v to_o the_o place_n some_o empiric_n use_v in_o the_o room_n of_o cantharides_n a_o mass_n of_o the_o leaf_n of_o crowfoot_n or_o flamula_fw-la jovis_n bruise_v on_o the_o place_n by_o which_o the_o scarf-skin_n be_v blister_v or_o rather_o eat_v the_o skin_n itself_o as_o if_o touch_v with_o a_o actual_a fire_n be_v much_o inflame_v and_o deep_o ulcerate_v whence_o not_o only_o a_o profusion_n of_o ichor_n but_o a_o inflammation_n of_o the_o whole_a member_n and_o a_o feverish_a disposition_n sometime_o follow_v wherefore_o these_o thing_n be_v not_o to_o be_v use_v rash_o 2._o operate_v 2._o how_o they_o operate_v if_o it_o be_v inquire_v of_o the_o manner_n and_o reason_n how_o these_o and_o other_o vesicatories_n operate_v in_o the_o first_o place_n we_o ought_v to_o show_v by_o what_o manner_n actual_a fire_n and_o thing_n endue_v with_o particle_n proceed_v from_o fire_n do_v raise_v a_o blister_n then_o by_o a_o easy_a analogy_n the_o force_n and_o manner_n of_o work_v of_o those_o sort_n of_o remedy_n will_v be_v know_v which_o be_v report_v to_o be_v endow_v with_o a_o potential_a fire_n wherefore_o we_o observe_v of_o the_o former_a that_o the_o fiery_a particle_n not_o be_v too_o vehement_o apply_v penetrate_v the_o scarf-skin_n without_o dissolution_n of_o unity_n enter_v under_o the_o skin_n itself_o fire_n show_v by_o the_o example_n of_o fire_n where_o the_o extremity_n of_o the_o vessel_n bring_v blood_n of_o the_o nerve_n and_o of_o the_o nervons_fw-fr fibres_fw-fr be_v terminate_v and_o there_o do_v various_o twist_v together_o these_o alter_v they_o from_o their_o position_n and_o pervert_v the_o structure_n of_o the_o whole_a texture_n of_o the_o skin_n insomuch_o that_o from_o all_o the_o vessel_n be_v make_v angry_a in_o a_o high_a degree_n the_o watery_a humour_n be_v imbue_v with_o igneous_a particle_n and_o therefore_o reject_v as_o well_o by_o the_o blood_n as_o by_o the_o nervous_a juice_n be_v spew_v out_o in_o great_a abundance_n this_o lympha_fw-la because_o it_o can_v pass_v through_o the_o scarf-skin_n separate_v it_o from_o the_o skin_n and_o raise_v it_o into_o a_o bladdery_a bulk_n from_o which_o at_o length_n be_v break_v of_o its_o own_o accord_n or_o occasional_o it_o flow_v out_o moreover_o as_o long_o as_o the_o igneous_a particle_n adhere_v to_o the_o skin_n and_o the_o mouth_n of_o the_o vessel_n be_v cover_v with_o a_o eschar_n be_v not_o close_v up_o these_o be_v continual_o twitch_v by_o they_o do_v continue_v to_o spew_v out_o the_o ichor_n this_o kind_n of_o ichorous_a flux_n will_v the_o soon_o cease_v if_o immediate_o upon_o the_o hurt_n inflict_v the_o fiery_a particle_n be_v draw_v out_o by_o the_o application_n of_o some_o proper_a antipyretick_n as_o fire_n itself_o nitre_n soap_n onion_n and_o the_o like_a moreover_o it_o run_v the_o long_o if_o omit_v a_o antipyretick_n medicine_n hinder_v the_o generation_n of_o a_o cicatrice_n or_o of_o the_o outer-skin_n and_o unlock_v the_o mouth_n of_o the_o vessel_n be_v wear_v upon_o the_o place_n affect_v by_o these_o it_o be_v easy_a to_o understand_v by_o what_o manner_n vesicatory_n perform_v their_o operation_n water_n how_o cantharides_n excite_v blister_n and_o draw_v forth_o water_n viz._n cantharides_n as_o likewise_o any_o other_o of_o the_o same_o virtue_n be_v outward_o apply_v and_o be_v heat_v by_o effluvia_n of_o the_o part_n subject_v and_o so_o be_v provoke_v to_o exert_v their_o power_n do_v plentiful_o dispatch_v sharp_a and_o as_o it_o be_v fiery_a particle_n from_o themselves_o which_o penetrate_v the_o scarf-skin_n without_o any_o tear_v it_o they_o be_v dash_v against_o the_o cutis_fw-la or_o other_o skin_n where_o first_o they_o act_n upon_o the_o spirit_n and_o then_o by_o the_o affect_v these_o upon_o the_o humour_n and_o solid_a part_n they_o very_o much_o provoke_v the_o spirit_n and_o drive_v they_o into_o painful_a convulsion_n of_o the_o fibre_n dissolve_v the_o humour_n and_o constrain_v they_o to_o separate_v into_o part_n so_o that_o the_o watery_a part_n be_v very_o much_o embue_v with_o those_o sharp_a and_o as_o it_o be_v venomous_a particle_n be_v reject_v every_o where_n by_o the_o other_o juice_n and_o when_o in_o the_o mean_a time_n the_o end_n of_o the_o vessel_n and_o fibre_n be_v either_o eat_v by_o the_o burn_a or_o open_v by_o twitch_a and_o as_o it_o be_v drain_v that_o ichor_n convey_v the_o hurtful_a particle_n be_v plentiful_o spew_v out_o of_o their_o little_a mouth_n which_o then_o separated_n the_o impervious_a cuticula_fw-la or_o the_o scarf-skin_n from_o the_o other_o skin_n or_o cutis_fw-la be_v self_n and_o raise_v it_o into_o a_o little_a bladder_n and_o after_o this_o be_v beoken_v and_o take_v away_o it_o be_v for_o some_o time_n pour_v out_o by_o the_o ulcerate_v shin_n as_o we_o show_v it_o to_o come_v to_o pass_v by_o reason_n of_o the_o particle_n of_o fire_n but_o this_o be_v not_o only_o do_v because_o the_o serous_a juice_n imbibe_v the_o sharp_a part_n of_o the_o medicine_n and_o convey_v they_o out_o do_v not_o always_o bear_v they_o all_o back_o the_o same_o way_n by_o which_o they_o enter_v but_o sometime_o this_o be_v endue_v with_o these_o sting_n regurgitate_v into_o the_o mass_n of_o bloodl_n and_o afterward_o be_v circulate_v with_o it_o and_o eject_v with_o its_o infestous_a burden_n through_o other_o emunctory_n dysurie_n why_o they_o bring_v a_o fervent_a dysurie_n offend_v some_o weak_a or_o tender_a channel_n in_o its_o passage_n or_o go_v forth_o from_o whence_o very_o many_o contract_n a_o strangury_n from_o great_a or_o many_o vesicatories_n by_o reason_n of_o the_o urinary_a passage_n be_v affect_v for_o that_o cause_n with_o acrimony_n or_o erosion_n which_o in_o some_o become_v most_o sharp_a and_o intolerable_a also_o that_o application_n sometime_o bring_v bloody_a urine_n to_o other_o afflict_v with_o the_o stone_n hence_o a_o suspicion_n also_o arise_v that_o those_o who_o have_v tender_a lung_n or_o who_o be_v subject_a to_o a_o consumption_n be_v much_o endager_v by_o this_o medicine_n outward_o apply_v which_o notwithstanding_o i_o have_v not_o know_v happen_v to_o any_o but_o can_v reather_n attest_v by_o frequent_a experience_n on_o the_o other_o side_n that_o it_o redound_v to_o advantage_n rather_o than_o hurt_v for_o the_o more_o sharp_a particle_n of_o cantharides_n if_o they_o be_v long_o apply_v be_v sometime_o imbibe_v more_o plentiful_o by_o the_o blood_n infect_v its_o whole_a serum_n which_o juice_n so_o sharpen_v as_o long_o as_o it_o be_v confound_v with_o the_o balsamic_a blood_n hurt_v no_o part_n but_o be_v separate_v from_o it_o by_o the_o kidney_n it_o sometime_o bring_v hurt_v to_o they_o and_o frequent_o not_o only_a twitch_n the_o neck_n of_o the_o bladder_n by_o its_o acrimony_n but_o sometime_o corrode_a it_o cause_n filth_n and_o little_a skin_n nay_o and_o blood_n to_o come_v away_o but_o in_o the_o mass_n of_o blood_n the_o same_o more_o sharp_a saline-volatile_a particle_n do_v often_o most_o notable_o help_v inasmuch_o as_o they_o destroy_v the_o fix_a or_o acid_a salt_n in_o it_o and_o unlock_v the_o consistence_n of_o the_o blood_n too_o much_o bind_v up_o and_o so_o do_v cause_n the_o serous_a and_o other_o morbific_a recrement_n before_o wrap_v up_o with_o it_o to_o be_v separate_v from_o it_o and_o to_o be_v more_o easy_o dispatch_v by_o urine_n and_o sweat_n urine_n vesicatories_n move_v sweat_n and_o urine_n hence_o vesicatory_n be_v apply_v long_o in_o fever_n do_v call_v forth_o plentiful_a urine_n and_o a_o more_o easy_a sweat_n also_o they_o open_v the_o obstruct_a way_n and_o move_v together_o the_o portion_n of_o blood_n or_o serum_n stagnate_v or_o be_v extravasated_a in_o any_o place_n and_o restore_v they_o to_o their_o circulation_n wherefore_o they_o be_v not_o use_v only_o to_o help_v in_o serous_a malady_n but_o also_o in_o those_o of_o the_o blood_n yea_o in_o a_o pleurisy_n peripneumonia_n and_o in_o any_o other_o fever_n have_v hitherto_o show_v after_o what_o manner_n vesicatory_n operate_v first_o on_o the_o spirit_n and_o then_o on_o the_o humour_n and_o solid_a part_n it_o be_v now_o our_o business_n in_o the_o next_o place_n to_o show_v both_o the_o good_a and_o evil_a effectg_n of_o they_o as_o also_o the_o manner_n of_o
use_v they_o but_o that_o they_o in_o the_o first_o place_n operate_v on_o the_o spirit_n be_v manifest_a from_o hence_o that_o they_o exert_v no_o power_n on_o the_o decease_a and_o it_o be_v a_o ill_a omen_n in_o those_o that_o be_v languish_v when_o vesicatory_n have_v no_o operation_n because_o it_o be_v a_o indication_n that_o the_o animal_n spirit_n be_v much_o deject_v or_o abundant_o diminish_v thereofre_o vesicatories_n the_o effect_n of_o vesicatories_n it_o behoove_v to_o consider_v about_o the_o due_a unfolding_n the_o energy_n force_n or_o virtue_n of_o this_o remedy_n what_o humour_n it_o either_o immediate_o or_o mediate_o evacuate_v or_o alter_v and_o afterward_o in_o what_o disease_n and_o body_n how_o dispose_v it_o either_o profit_n or_o hurt_n first_o skin_n 1._o as_o to_o humour_n of_o the_o skin_n as_o to_o the_o former_a the_o humour_n that_o be_v immediate_o send_v out_o by_o a_o vesicatory_a drop_v forth_o partly_o from_o the_o pore_n and_o glandule_n of_o the_o skin_n and_o partly_o out_o of_o the_o mouth_n of_o the_o little_a artery_n and_o partly_o out_o of_o the_o extremity_n of_o the_o nervous_a fibres_fw-fr perhaps_o some_o little_a of_o the_o juice_n new_o receive_v out_o of_o the_o mouth_n of_o the_o vein_n though_o not_o much_o seem_v to_o be_v carry_v back_o the_o humour_n mediate_o draw_v out_o by_o a_o vesicatory_a be_v those_o which_o the_o aforesaid_a part_n be_v empty_v receive_v elsewhere_o and_o derive_v they_o forth_o 1._o the_o skin_n be_v a_o thick_a memgbrane_n consist_v of_o a_o double_a coat_n very_o porous_a also_o thick_o set_v about_o with_o most_o numerous_a galndule_n with_o fat_a as_o also_o the_o end_n of_o the_o vessel_n and_o fibre_n be_v terminate_v therein_o and_o thick_o weave_v one_o within_o another_o wherefore_o while_o a_o portion_n of_o it_o be_v make_v bare_a the_o scarsskin_n be_v take_v off_o with_o a_o vesicatory_a and_o the_o nervous_a sibre_n be_v twitch_v do_v bound_v together_o and_o wreathe_v the_o glandule_n and_o pore_n the_o serous_a humour_n contain_v in_o both_o be_v most_o plentiful_o squeeze_v out_o and_o whereas_o some_o pore_n be_v pervious_a into_o other_o the_o serum_n do_v not_o only_o flow_v out_o of_o the_o place_n blister_a but_o sometime_o into_o the_o little_a hole_n first_o so_o empty_v a_o portion_n of_o the_o serum_n come_v from_o the_o neighbour_a pore_n succeed_v and_o thence_o by_o and_o by_o sweat_v out_o wherefore_o in_o patient_n affect_v with_o a_o anasarca_n the_o little_a ulcer_n raise_v by_o a_o vesicatory_a exhaust_v the_o water_n every_o where_n in_o great_a plenty_n and_o draw_v they_o out_o of_o the_o neighbourhood_n yea_o and_o sometime_o at_o a_o great_a distance_n 2._o blood_n 2._o in_o respect_n of_o the_o blood_n the_o little_a mouth_n of_o the_o artery_n be_v uncover_v and_o twitch_v about_o the_o blister_a place_n do_v not_o only_o vomit_v out_o a_o portion_n of_o the_o serum_n bring_v to_o they_o by_o ordinary_a custom_n but_o the_o serous_a liquor_n be_v imbue_v with_o the_o stimula_n of_o the_o medicine_n in_o the_o whole_a mass_n of_o blood_n immediate_o be_v separate_v more_o plentiful_o from_o the_o blood_n and_o at_o every_o turn_n of_o circulation_n a_o great_a plenty_n thereof_o be_v throw_v out_o by_o the_o same_o mouth_n of_o the_o artery_n continual_o irritate_v alter_v which_o they_o purge_v and_o alter_v moreover_o together_o with_o the_o serum_n as_o it_o be_v so_o stagnate_v and_o therefore_o remove_v from_o the_o whole_a blood_n into_o the_o little_a ulcer_n of_o the_o skin_n other_o recrement_n and_o sometime_o the_o morbific_a matter_n itself_o depart_v in_o plenty_n and_o be_v dispatch_v forth_o by_o the_o same_o emissary_n and_o for_o this_o reason_n in_o malignant_a fever_n yea_o in_o some_o putrid_a that_o be_v difficult_a to_o be_v judge_v of_o when_o the_o recrement_n and_o corruption_n of_o the_o blood_n unapt_a to_o be_v throw_v off_o do_v threaten_v the_o praecordia_fw-la or_o brain_n vesicatory_n continual_o and_o leisurely_o drain_n it_o do_v frequent_o yield_v notable_a relief_n whereunto_o we_o may_v add_v that_o they_o do_v also_o alter_v and_o restore_v as_o we_o before_o mentine_v the_o blood_n degenerate_a or_o deprave_v as_o to_o its_o salt_n and_o also_o by_o open_v or_o subtili_v its_o consistence_n dispose_v it_o towards_o a_o eucrasie_n wherefore_o not_o only_o in_o a_o seaverish_a state_n of_o blood_n but_o also_o in_o a_o state_n otherwise_o peccant_a or_o of_o ill_a juice_n this_o kind_n of_o remedy_n be_v often_o extreme_o convenient_a 3._o part_n 3._o in_o respect_n of_o the_o nerve_n and_o of_o the_o humour_n abound_v in_o they_o and_o in_o the_o nervous_a part_n both_o reason_n and_o experience_n have_v enough_o prove_v that_o vesicatories_n evacuate_v a_o certain_a humour_n from_o the_o nerve_n and_o nervous_a fibres_n and_o for_o that_o cause_n profit_n very_o much_o in_o convulsive_a distemper_n for_o sure_o we_o have_v in_o another_o place_n clear_o enouth_n demonstrate_v that_o the_o watery_a liquor_n of_o the_o brain_n and_o nervous_a sytem_n do_v sometime_o abound_v with_o heterogeneous_a particle_n also_o it_o be_v manifest_a by_o frequent_a and_o familiar_a observation_n that_o the_o impurity_n and_o recrement_n of_o that_o liquor_n together_o with_o the_o watery_a juice_n do_v spontaneous_o sweat_v out_o from_o the_o nerve_n and_o nervous_a fibres_n when_o the_o fluor_fw-la be_v raise_v and_o either_o restagnate_n within_o the_o mass_n of_o blood_n be_v carry_v off_o by_o urine_n or_o by_o sweat_v or_o be_v deposit_v within_o the_o cavity_n of_o the_o bowel_n be_v dispatch_v by_o vomit_n or_o stool_n wherefore_o when_o a_o vesicatory_a be_v apply_v the_o extremity_n of_o the_o nerve_n and_o nervous_a fibres_n be_v make_v bare_a and_o very_o much_o anger_v immediate_o a_o humour_n abound_v near_o their_o end_n be_v void_v and_o also_o the_o whole_a juice_n plant_v within_o their_o passage_n by_o a_o long_a succession_n be_v chafe_v and_o deliver_v from_o stagnation_n and_o the_o heterogeneous_a particle_n mix_v with_o that_o nervous_a juice_n be_v every_o where_o agitate_a and_o derive_v from_o the_o brain_n slide_v towards_o their_o new_o open_a emissary_n by_o degree_n and_o at_o length_n be_v remove_v whole_o forth_o from_o these_o thing_n we_o may_v collect_v convenient_a for_o the_o cure_n of_o what_o disease_n vesicatory_n be_v convenient_a for_o the_o cure_n of_o what_o disease_n this_o kind_n of_o remedy_n do_v chief_o conduce_v for_o by_o reason_n of_o its_o evacuation_n out_o of_o the_o pore_n and_o glandule_n of_o the_o skin_n as_o often_o as_o any_o serous_a salt_n sharp_a or_o otherwise_o hurtful_a humour_n be_v collect_v in_o those_o part_n or_o their_o neighbourhood_n and_o be_v exclude_v from_o the_o circulation_n of_o blood_n shall_v obstinate_o stick_v in_o that_o place_n sure_o there_o be_v no_o more_o ready_a or_o easy_a way_n afford_v for_o drawintg_v it_o forth_o than_o by_o apply_v a_o vesicatory_a distemper_n 1._o in_o all_o cutaneous_a distemper_n upon_o or_o below_o the_o place_n affect_v wherefore_o it_o be_v not_o only_o indicate_v by_o a_o anasarca_n or_o by_o any_o foulness_n or_o eruption_n of_o the_o skin_n but_o moreover_o a_o vesicatory_a be_v require_v for_o pain_n either_o arthritical_a or_o scorbutical_a fix_v any_o where_o in_o the_o extern_a habit_n of_o the_o body_n or_o in_o any_o certain_a member_n second_o in_o respect_n of_o the_o blood_n vesictatories_n be_v always_o use_v in_o malignant_a fever_n blood_n 2._o they_o take_v away_o the_o impurity_n and_o ill_a temperament_n of_o the_o blood_n as_o well_o to_o purge_v out_o leisurely_o any_o heterogeneous_a or_o morbific_a matter_n as_o to_o change_v it_o from_o a_o disposition_n either_o too_o acid_a or_o salt_n or_o otherwise_o peccant_a into_o a_o right_a temperament_n yea_o they_o be_v of_o most_o excellent_a use_n in_o all_o putrid_a fever_n of_o ill_a habit_n and_o hard_a to_o be_v judge_v of_o also_o for_o that_o cause_n in_o the_o scurvy_a leucophlegmatia_fw-la part_n this_o remedy_n be_v profitable_a in_o those_o disease_n which_o the_o blood_n produce_v in_o other_o part_n pica_n virginum_fw-la or_o green_a sickness_n also_o in_o any_o other_o ill_a habit_n of_o body_n this_o kind_n of_o remedy_n afford_v frequent_o notable_a help_n moreover_o not_o only_o for_o the_o sake_n of_o correct_v the_o blood_n itself_o but_o beside_o as_o often_o as_o it_o be_v deprave_v spread_v its_o corruption_n on_o other_o part_n and_o so_o do_v first_o beget_v disease_n in_o the_o head_n the_o chest_n the_o nether_a belly_n or_o member_n and_o then_o excite_v their_o fit_n vesicatory_n be_v usual_o exhibit_v with_o success_n wherefore_o it_o be_v a_o common_a remedy_n in_o headache_n a_o vertigo_n and_o soporiferous_a affection_n no_o less_o than_o in_o a_o catarrh_n or_o any_o defluxion_n either_o into_o the_o eye_n nose_n palate_n or_o lung_n in_o which_o