a_o very_o long_o and_o lavish_a use_n thereof_o the_o inconvenience_n of_o leave_v off_o the_o use_n of_o opium_n do_v bear_v a_o certain_a proportion_n to_o the_o time_n and_o quantity_n that_o it_o have_v be_v use_v in_o 1._o note_v that_o the_o turk_n do_v drink_v some_o water_n always_o after_o the_o take_n of_o opium_n as_o be_v the_o best_a menstruum_fw-la to_o dissolve_v it_o 2._o note_v that_o it_o be_v usual_a with_o they_o to_o take_v a_o drachm_n in_o the_o morning_n and_o so_o much_o in_o the_o afternoon_n and_o so_o may_v we_o as_o well_o as_o they_o if_o use_v to_o it_o and_o it_o be_v a_o very_a silly_a say_n that_o you_o will_v find_v in_o author_n that_o they_o be_v better_a able_a to_o bear_v it_o because_o of_o the_o climate_n etc._n etc._n whereas_o the_o more_o northern_a person_n be_v better_a able_a to_o take_v it_o than_o the_o southern_a as_o will_v hereafter_o appear_v most_o plain_o i_o be_o tell_v of_o one_o near_o banbury_n that_o take_v two_o ounce_n a_o day_n 3._o note_v that_o among_o the_o effect_n of_o opium_n may_v be_v observe_v many_o seem_a contradiction_n yet_o be_v there_o nothing_o more_o certain_a than_o the_o several_a different_a matter_n of_o fact_n which_o no_o doubt_n have_v be_v a_o great_a cause_n to_o puzzle_v the_o world_n about_o it_o and_o to_o run_v man_n into_o strange_a absurdity_n concern_v its_o operation_n and_o all_o to_o deviate_v so_o far_o from_o the_o truth_n that_o nothing_o in_o nature_n can_v be_v far_o unless_o you_o will_v say_v that_o heat_n cool_v or_o what_o please_v the_o sensitive_a soul_n be_v at_o the_o same_o time_n abhor_v by_o it_o now_o because_o these_o seem_a contradiction_n in_o the_o effect_n of_o opium_n be_v the_o great_a rub_n to_o be_v meet_v with_o and_o that_o the_o reader_n may_v take_v the_o better_a estimate_n of_o the_o undertake_n and_o my_o explication_n of_o its_o effect_n when_o i_o come_v to_o it_o i_o shall_v not_o fear_v to_o enumerate_v they_o distinct_o though_o they_o will_v make_v the_o strange_a catalogue_n of_o riddle_n that_o ever_o be_v see_v trust_v in_o he_o that_o create_v this_o wonderful_a medicament_n that_o he_o will_v enable_v i_o to_o explain_v all_o its_o effect_n the_o seem_a contradiction_n in_o the_o effect_n of_o opium_n 1._o it_o cause_v sleep_v and_o watch_v 2._o it_o cause_n and_o prevent_v sweat_n 3._o it_o relax_n and_o stop_v looseness_n 4._o it_o stop_v flux_n and_o cause_n that_o of_o sweat_n etc._n etc._n 5._o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v by_o that_o sense_n to_o venery_n 6._o it_o cause_v stupidity_n and_o promptitude_n in_o business_n cloudiness_n and_o serenity_n of_o mind_n 7._o it_o excite_v the_o spirit_n and_o quiet_v they_o 8._o it_o be_v very_o hot_a yet_o cool_v in_o fever_n 9_o it_o be_v hot_a and_o bitter_a yet_o lessen_v appetite_n even_o in_o cold_a stomach_n 10._o it_o stop_v and_o promote_v urine_n 11._o it_o relax_n and_o weaken_v yet_o enable_v we_o to_o undergo_v labour_n journey_n etc._n etc._n 12._o it_o cause_n and_o prevent_v abortion_n 13._o it_o stop_v vomit_v above_o all_o thing_n yet_o cause_n most_o violent_a tedious_a and_o dangerous_a vomit_n 14._o it_o stop_v purge_v in_o a_o most_o eminent_a manner_n yet_o sometime_o cause_v it_o 15._o it_o be_v very_o acrimonious_a yet_o as_o all_o say_v obtund_v acrimony_n however_o it_o allay_v pain_n proceed_v from_o acrimony_n 16._o it_o cause_v a_o furious_a madness_n yet_o compose_v the_o spirit_n above_o all_o thing_n 17._o it_o cause_v 〈◊〉_d yet_o sometime_o cure_v they_o as_o willis_n say_v 18._o it_o cause_v palsy_n yet_o have_v i_o know_v it_o to_o cure_v a_o palsy_n 19_o it_o cause_v dryness_n in_o the_o mouth_n yet_o take_v off_o thirst_n in_o fever_n 20._o it_o cure_v and_o cause_v a_o hiccough_n 21._o it_o stanche_n blood_n yet_o cause_v the_o blood_n to_o come_v outward_a as_o appear_v by_o the_o efflorescence_n or_o redness_n of_o the_o skin_n that_o it_o cause_n yet_o move_v the_o menses_fw-la and_o lochia_n 22._o we_o have_v many_o instance_n of_o it_o promote_a and_o hinder_v critical_a motion_n 23._o it_o raise_v very_o weak_a people_n when_o nothing_o beside_o will_v do_v it_o yet_o it_o kill_v other_o weak_a people_n 24._o it_o cause_n and_o cure_n convulsion_n 25._o it_o cause_v relaxation_n and_o contraction_n of_o the_o same_o part_n 26._o it_o relax_n yet_o cause_v rigidity_n tension_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n thus_o have_v i_o fair_o and_o faithful_o lay_v the_o whole_a onus_fw-la of_o the_o operation_n effect_n and_o contradictory_n phenomena_n of_o opium_n upon_o my_o shoulder_n however_o i_o come_v off_o and_o clear_v myself_o of_o the_o intricacy_n maze_n and_o cross_a effect_n thereof_o by_o explain_v they_o which_o none_o upon_o the_o view_n thereof_o will_v think_v possible_a and_o none_o before_o i_o dare_v as_o much_o as_o enumerate_v for_o that_o end_n chap._n vii_o the_o author_n contrive_v a_o compendious_a way_n of_o examine_v all_o opinion_n concern_v the_o operation_n of_o opium_n have_v without_o any_o sly_a or_o sordid_a evasion_n or_o considerable_a omission_n which_o have_v be_v the_o perfidious_a course_n of_o author_n in_o this_o case_n full_o and_o true_o enumerate_v the_o sensible_a and_o certain_a effect_n of_o opium_n in_o humane_a body_n and_o thereby_o empanneled_a a_o just_a jury_n for_o the_o trial_n of_o hypothesise_n which_o must_v be_v judge_v by_o the_o effect_n or_o phenomena_n of_o opium_n i_o will_v now_o proceed_v to_o their_o examination_n but_o because_o it_o will_v be_v endless_a to_o take_v every_o one_o particular_o into_o consideration_n i_o will_v use_v their_o stratagem_n who_o blow_v up_o foundation_n to_o save_v the_o tedious_a peck_v at_o all_o the_o part_n of_o the_o superstructure_n which_o in_o this_o case_n will_v require_v a_o age_n and_o take_v up_o all_o my_o time_n in_o demolish_n they_o which_o may_v be_v better_o employ_v in_o erect_v something_o that_o may_v be_v useful_a i_o have_v consider_v and_o find_v that_o the_o foundation_n in_o which_o all_o author_n both_o ancient_a and_o modern_a agree_v and_o whereupon_o they_o have_v hitherto_o endeavour_v to_o build_v look_v upon_o it_o as_o firm_a and_o warrantable_a in_o all_o age_n be_v this_o viz._n that_o opium_n operate_v by_o diminish_v or_o disable_n the_o spirit_n mean_v the_o animal_n spirit_n the_o ancient_n affirm_v that_o it_o do_v so_o by_o a_o extreme_a cold_a quality_n etc._n etc._n and_o the_o modern_n who_o observe_v it_o to_o act_n while_o it_o be_v at_o stomach_n by_o affect_v the_o brain_n nerve_n animal_n spirit_n etc._n etc._n and_o conclude_v no_o action_n be_v perform_v without_o contact_n infer_v and_o agree_v because_o no_o visible_a passage_n can_v be_v find_v from_o the_o stomach_n to_o the_o head_n that_o it_o must_v of_o absolute_a necessity_n act_v by_o fume_n vapour_n auras_fw-la or_o effluvium_n send_v up_o out_o of_o the_o stomach_n to_o the_o brain_n nerve_n etc._n etc._n so_o that_o all_o the_o remain_a question_n among_o the_o modern_n be_v which_o way_n those_o fume_n or_o vapour_n do_v the_o feat_n all_o allow_v the_o fume_n do_v it_o one_o say_v that_o they_o stuff_v the_o pore_n of_o the_o brain_n and_o so_o hinder_v the_o generation_n of_o animal_n spirit_n a_o second_o that_o they_o constringed_a and_o close_v the_o pore_n together_o thereby_o hinder_v the_o say_a generation_n a_o three_o that_o they_o fix_v and_o coagulate_v the_o animal_n spirit_n as_o wedelius_n and_o other_o a_o four_o that_o they_o cloud_v the_o animal_n spirit_n a_o five_o that_o they_o act_v as_o a_o poison_n as_o willis_n and_o many_o other_o a_o six_o that_o they_o clog_v the_o animal_n spirit_n by_o adhere_v to_o they_o etc._n etc._n not_o know_v nor_o i_o think_v care_v what_o they_o say_v so_o they_o humour_a their_o own_o imagination_n and_o hypothesise_n though_o utter_o incapable_a of_o solve_v the_o effect_n of_o opium_n especial_o be_v most_o constant_a proper_a and_o genuine_a effect_n for_o how_o can_v a_o cold_a quality_n which_o opium_n never_o have_v cause_v a_o gay_a and_o brisk_a humour_n bravery_n magnanimity_n euphory_n in_o labour_n promptitude_n to_o venus_n etc._n etc._n and_o how_o can_v cloud_n of_o vapour_n hinder_v the_o generation_n of_o animal_n spirit_n by_o stuff_v or_o constr_v the_o pore_n of_o the_o brain_n poison_v fix_v coagulate_v clog_a or_o cloud_v the_o animal_n spirit_n cause_v a_o fine_a ovation_n thereof_o a_o gay_a brave_a courageous_a and_o magnanimous_a disposition_n euphory_n promptitude_n to_o venery_n serenity_n expediteness_n in_o management_n etc._n etc._n which_o be_v as_o have_v be_v say_v the_o constant_a and_o proper_a effect_n of_o opium_n nor_o indeed_o be_v any_o of_o those_o author_n so_o foolhardy_a as_o to_o attempt_v it_o
good_a humour_a of_o which_o he_o be_v seldom_o capable_a and_o utter_o incapable_a of_o all_o or_o most_o of_o the_o other_o brisk_a effect_n as_o euphory_n promptitude_n to_o venus_n exertion_n of_o courage_n etc._n etc._n it_o be_v either_o pass_v by_o as_o a_o ordinary_a thing_n of_o course_n and_o so_o not_o heed_v or_o else_o impute_v to_o refreshment_n by_o sleep_n ease_n from_o pain_n or_o some_o amendment_n as_o to_o the_o disease_n or_o indeed_o to_o any_o thing_n rather_o than_o dispiriting_n and_o stupify_a opium_n that_o be_v so_o far_o in_o all_o opinion_n from_o exciting_a the_o spirit_n that_o all_o affirm_v conclude_v and_o agree_v that_o it_o diminish_v or_o disable_v they_o the_o like_a be_v to_o be_v say_v of_o any_o of_o the_o lively_a effect_n in_o case_n they_o happen_v and_o be_v observe_v though_o i_o do_v not_o see_v how_o they_o can_v so_o at_o least_o as_o any_o slander_n by_o will_v refer_v it_o to_o opium_n beside_o that_o as_o to_o some_o of_o the_o brisk_a effect_n especial_o that_o of_o venery_n great_a dose_n be_v requisite_a to_o render_v it_o any_o thing_n remarkable_a than_o be_v use_v in_o these_o western_a part_n and_o that_o modesty_n will_v much_o hinder_v the_o discovery_n of_o this_o effect_n be_v it_o not_o therefore_o very_o manifest_a that_o i_o have_v great_a cause_n to_o suspect_v that_o both_o ancient_n and_o modern_a physician_n consider_v thing_n by_o half_n since_o they_o do_v not_o take_v the_o most_o genuine_a property_n into_o their_o consideration_n and_o that_o they_o lay_v their_o foundation_n upon_o the_o most_o contrary_a effect_n to_o they_o it_o follow_v then_o that_o the_o general_a supposition_n of_o all_o the_o learned_a can_v no_o more_o solve_v the_o true_a property_n of_o opium_n in_o any_o probability_n than_o give_v the_o reason_n why_o fire_n harden_v clay_n can_v explain_v why_o it_o soften_v wax_n the_o reason_n do_v i_o say_v i_o shall_v have_v say_v than_o give_v the_o wrong_a reason_n why_o it_o harden_v clay_n show_v how_o it_o soften_v wax_n for_o it_o will_v appear_v in_o the_o follow_a chapter_n that_o they_o give_v no_o right_a reason_n for_o any_o effect_n of_o opium_n even_o those_o they_o ever_o allow_v to_o be_v its_o effect_n nor_o lay_v any_o true_a foundation_n to_o explain_v the_o least_o mean_a and_o plain_a effect_n thereof_o forasmuch_o as_o all_o their_o supposition_n be_v so_o false_a that_o there_o never_o be_v any_o such_o thing_n as_o they_o lie_v down_o to_o explain_v the_o effect_n of_o opium_n viz._n 1._o no_o such_o thing_n as_o a_o cold_a quality_n in_o opium_n 2._o no_o such_o thing_n as_o fume_n etc._n etc._n fly_v from_o opium_n to_o the_o brain_n while_o it_o be_v at_o stomach_n 3._o no_o such_o thing_n as_o diminish_v or_o disable_n the_o animal_n spirit_n by_o opium_n any_o way_n whatsoever_o of_o which_o in_o their_o order_n in_o the_o follow_a chapter_n chap._n ix_o it_o be_v prove_v that_o opium_n have_v no_o cold_a quality_n to_o diminish_v or_o disable_v the_o spirit_n thereby_o have_v show_v just_a cause_n of_o my_o suspicion_n of_o that_o universal_a foundation_n of_o opium_n diminish_v or_o disable_n the_o spirit_n i_o will_v now_o proceed_v to_o a_o more_o strict_a examination_n thereof_o beginning_n with_o the_o opinion_n of_o the_o ancient_n who_o affirm_v that_o opium_n diminish_v or_o disable_v the_o spirit_n by_o a_o extreme_a cold_a quality_n i_o confess_v that_o much_o may_v be_v do_v towards_o the_o diminish_n or_o disable_n the_o spirit_n by_o opium_n if_o it_o have_v such_o a_o cold_a quality_n as_o the_o ancient_n attribute_v to_o it_o for_o than_o it_o must_v be_v such_o a_o coldness_n as_o the_o cold_a thing_n either_o actual_a or_o potential_a bear_v no_o proportion_n to_o for_o ice_n snow_n etc._n etc._n bear_v no_o proportion_n to_o it_o in_o cause_v the_o same_o effect_n by_o a_o cold_a quality_n it_o be_v the_o manner_n of_o the_o ancient_n implicit_o to_o believe_v and_o subscribe_v to_o what_o their_o great_a author_n and_o master_n in_o physic_n or_o philosophy_n teach_v they_o who_o they_o adore_v as_o infallible_a god_n as_o soon_o as_o their_o mortality_n prove_v the_o contrary_a which_o be_v as_o absurd_a as_o assert_v tha_z opium_n which_o be_v one_o of_o the_o hot_a thing_n that_o vegetable_n afford_v be_v extreme_a cold_a bless_a be_v god_n for_o our_o light_n in_o religion_n and_o liberty_n in_o philosophy_n therefore_o some_o such_o admire_a author_n or_o great_a master_n in_o physic_n have_v assert_v that_o opium_n act_v by_o a_o extreme_a cold_a quality_n all_o do_v implicit_o subscribe_v to_o it_o the_o devil_n who_o they_o worship_v can_v not_o though_o a_o deceiver_n from_o the_o beginning_n impose_v more_o upon_o their_o faith_n than_o in_o cause_v they_o for_o i_o can_v think_v but_o it_o be_v some_o such_o evil_a power_n to_o believe_v that_o opium_n be_v cold_a against_o all_o the_o evidence_n of_o sense_n and_o experience_n he_o may_v have_v as_o well_o tell_v they_o that_o hell_n fire_n have_v all_o the_o property_n of_o common_a culinary_a fire_n and_o yet_o nothing_o more_o refresh_v by_o its_o cold_a quality_n for_o as_o many_o of_o our_o sense_n as_o can_v take_v notice_n of_o heat_n and_o cold_a do_v plain_o inform_v we_o that_o it_o be_v very_o hot_a in_o itself_o and_o effect_n for_o 1._o it_o be_v taste_n be_v very_o bitter_a rank_a vehement_o hot_a burn_a and_o bite_v all_o which_o quality_n be_v infallible_a sign_n of_o great_a heat_n and_o the_o better_a the_o opium_n be_v the_o more_o intense_a be_v those_o quality_n nay_o it_o be_v observe_v that_o its_o very_a virtue_n be_v strict_o combine_v to_o or_o consist_v in_o those_o quality_n especial_o bitterness_n which_o if_o lose_v the_o virtue_n be_v go_v as_o be_v common_o observe_v and_o easy_o observable_a it_o be_v a_o wise_a fetch_v of_o amatus_fw-la lusitanus_n in_o defence_n of_o its_o cold_a quality_n to_o attribute_v all_o its_o bitterness_n to_o glaucium_fw-la that_o be_v mix_v therewith_o whereas_o glaucium_fw-la always_o give_v a_o yellow_a tincture_n to_o water_n and_o opium_n a_o red_a but_o the_o opium_n that_o give_v no_o yellow_a tincture_n be_v bitter_a also_o yea_o that_o be_v most_o bitter_a that_o give_v the_o red_a tincture_n how_o come_v theban_a opium_n and_o indeed_o all_o other_o opium_n to_o be_v bitter_a before_o any_o thing_n be_v mix_v with_o it_o how_o inadvertent_o absurd_a people_n will_v be_v to_o defend_v absurdity_n it_o be_v pretty_a to_o see_v how_o they_o will_v expose_v themselves_o to_o defend_v a_o false_a opinion_n 2._o it_o be_v smell_n which_o be_v very_a rank_n strong_a hot_a and_o such_o as_o thing_n high_o impregnate_v with_o volatile_a salt_n and_o sulphur_n the_o two_o hot_a principle_n in_o nature_n do_v afford_v it_o be_v from_o volatile_a salt_n that_o cantharides_n pismire_n spear-wort_n crowsfoot_n etc._n etc._n be_v so_o very_o hot_a as_o to_o blister_v or_o exulcerate_v and_o be_v not_o all_o hot_a spirit_n such_o upon_o the_o account_n of_o their_o sulphur_n as_o spirit_n of_o wine_n brandy_n etc._n etc._n 3._o the_o best_a and_o strong_a opium_n will_v also_o exulcerate_v as_o all_o author_n agree_v which_o only_a fire_n or_o such_o thing_n as_o have_v the_o particle_n of_o fire_n lodge_v in_o they_o as_o lixiviate_n etc._n etc._n or_o the_o hot_a thing_n in_o nature_n will_v do_v as_o cantharides_n spear-wort_n etc._n etc._n it_o be_v 4._o for_o the_o like_a reason_n a_o psilothrick_n or_o causer_n of_o hair_n to_o fall_v which_o only_a lime_n orpâ—ment_n and_o the_o hot_a thing_n do_v cause_n 5._o it_o be_v inflammable_a which_o only_o sulphurecus_fw-la thing_n be_v 6._o it_o cause_v a_o sense_n of_o a_o vehement_a heat_n at_o stomach_n though_o take_v but_o in_o the_o quantity_n of_o a_o drachm_n 7._o it_o cause_v dryness_n of_o the_o mouth_n and_o thirst_v though_o take_v but_o in_o the_o quantity_n of_o 3_o grain_n which_o nothing_o do_v but_o hot_a thing_n 8._o it_o discuss_n and_o all_o discusser_n be_v hot_a for_o it_o be_v by_o heat_n that_o they_o do_v discuss_v as_o spirit_n of_o wine_n cummin-seed_n volatile_a salt_n and_o all_o hot_a spirit_n 9_o it_o soon_o operate_v and_o in_o a_o small_a quantity_n which_o be_v a_o infallible_a proof_n of_o the_o activity_n of_o its_o part_n which_o argue_v heat_n not_o cold._a 10._o it_o cause_v a_o gay_a pleasant_a and_o merry_a humour_n which_o only_a wine_n and_o hot_a liquor_n etc._n etc._n do_v and_o one_o grain_n of_o opium_n will_v cause_v they_o as_o much_o as_o several_a glass_n of_o wine_n which_o argue_v that_o its_o heat_n be_v much_o great_a 11._o i_o will_v fain_o know_v how_o or_o see_v any_o instance_n of_o any_o cold_a thing_n raise_v the_o spirit_n cause_v courage_n magnanimity_n enable_v people_n to_o labour_n journey_n etc._n
watch_n and_o sentinel_n to_o discover_v and_o give_v notice_n of_o what_o be_v or_o be_v not_o good_a and_o agreeable_a to_o our_o animal_n nature_n that_o upon_o notice_n of_o what_o be_v good_a and_o agreeable_a pleasure_n comfort_n satisfaction_n etc._n etc._n be_v conceive_v otherwise_o displeasure_n discomfort_n and_o dissatisfaction_n what_o diminish_v or_o disable_v our_o spirit_n do_v we_o the_o great_a evil_n that_o can_v be_v and_o consequent_o sensation_n will_v according_a to_o its_o office_n give_v we_o such_o notice_n thereof_o as_o will_v cause_v displeasure_n etc._n etc._n otherwise_o these_o sentinel_n that_o god_n and_o nature_n have_v appoint_v for_o faithful_a notice_n will_v instead_o of_o trusty_a service_n which_o be_v the_o end_n they_o be_v make_v for_o deceive_v we_o and_o consequent_o do_v we_o mischief_n rather_o than_o good_a which_o be_v very_o profane_a if_o not_o blasphemous_a to_o assert_v as_o be_v high_o abusive_a of_o god_n goodness_n and_o wisdom_n to_o make_v thing_n in_o nature_n that_o will_v not_o only_o not_o answer_n but_o act_n quite_o contrary_a to_o their_o end_n it_o follow_v then_o that_o what_o cause_v such_o a_o mighty_a agreeable_a and_o pleasant_a sensation_n at_o stomach_n which_o be_v the_o great_a and_o most_o accurate_a judge_n of_o what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n can_v be_v destructive_a or_o disable_n of_o its_o spirit_n which_o be_v the_o most_o excellent_a and_o useful_a thing_n that_o belong_v thereto_o therefore_o opium_n which_o so_o mighty_o recommend_v itself_o to_o please_v and_o comfort_v the_o great_a judge_n that_o god_n have_v give_v to_o a_o sensible_a creature_n to_o discern_v what_o be_v good_a and_o evil_a for_o it_o can_v diminish_v or_o disable_v our_o spirit_n one_o may_v say_v what_o i_o dare_v not_o that_o the_o sensation_n at_o stomach_n may_v deceive_v we_o we_o may_v deceive_v ourselves_o and_o say_v so_o when_o that_o which_o please_v the_o stomach_n do_v not_o please_v our_o pervert_v imagination_n which_o make_v no_o argument_n let_v we_o therefore_o consider_v thing_n where_o there_o be_v no_o such_o vain_a imagination_n to_o contradict_v the_o good_a end_n of_o nature_n if_o the_o stomach_n and_o sense_n in_o a_o brute_n or_o mere_a animal_n which_o have_v no_o other_o mean_n to_o judge_n of_o what_o be_v good_a or_o evil_n for_o it_o shall_v not_o judge_v aright_o all_o the_o animal_n in_o the_o whole_a world_n will_v soon_o perish_v it_o be_v the_o vain_a opinion_n of_o man_n that_o persuade_v they_o that_o thing_n be_v cold_a when_o hot_a etc._n etc._n as_o in_o the_o case_n of_o opium_n when_o the_o sense_n true_o inform_v that_o it_o be_v hot_a if_o you_o will_v stand_v to_o your_o imagination_n and_o supposition_n for_o such_o all_o must_v be_v without_o the_o information_n of_o sense_n against_o the_o dictate_v of_o sensation_n you_o must_v inevitable_o err_v but_o one_o may_v say_v be_v the_o sense_n at_o stomach_n such_o a_o infallible_a guide_n always_o i_o believe_v it_o will_v be_v very_o hard_a to_o give_v many_o instance_n to_o the_o contrary_a and_o prove_v it_o well_o however_o if_o we_o do_v or_o may_v allow_v something_o of_o this_o kind_a to_o a_o pervert_v stomach_n at_o certain_a time_n to_o avoid_v a_o squabble_n about_o it_o it_o be_v never_o to_o be_v allow_v that_o all_o the_o stomach_n in_o the_o whole_a world_n shall_v be_v please_v with_o one_o and_o the_o same_o thing_n at_o all_o time_n and_o yet_o that_o this_o thing_n shall_v be_v so_o high_o pernicious_a to_o the_o animal_n as_o to_o diminish_v or_o disable_v its_o spirit_n then_o indeed_o it_o will_v follow_v that_o the_o most_o exquisite_a sense_n at_o stomach_n to_o discern_v what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n be_v absolute_o in_o vain_a which_o no_o man_n of_o reason_n that_o have_v any_o apprehension_n of_o the_o wisdom_n of_o god_n and_o nature_n can_v assert_v 3._o what_o be_v more_o notorious_a than_o that_o pleasure_n or_o be_v please_v raise_v and_o displeasure_n or_o be_v grieve_v depress_n the_o spirit_n be_v not_o all_o people_n pleasant_a gay_a and_o good_a humour_a brisk_a prompt_a etc._n etc._n when_o please_v do_v not_o man_n travel_v or_o labour_n with_o more_o ease_n in_o pleasant_a company_n etc._n etc._n but_o of_o these_o matter_n and_o the_o reason_n thereof_o more_o in_o the_o follow_a chapter_n 4._o how_o can_v opium_n that_o revive_v people_n when_o they_o be_v so_o dispirited_a that_o they_o be_v even_o almost_o die_v as_o when_o opium_n be_v want_v by_o such_o as_o use_v to_o take_v it_o in_o deliquiâ—ms_n and_o agony_n from_o paiâ—_n etc._n etc._n diminish_v or_o disable_v the_o spirit_n it_o be_v plain_a contradiction_n to_o say_v that_o it_o shall_v next_o to_o opium_n nothing_o revive_v people_n in_o such_o case_n better_o than_o wine_n and_o those_o thing_n that_o produce_v the_o same_o or_o like_a effect_n have_v like_o nature_n and_o who_o can_v say_v that_o wine_n that_o be_v make_v to_o glad_a the_o heart_n of_o man_n diminish_v or_o disable_v the_o spirit_n or_o that_o opium_n which_o produce_v all_o the_o sprightly_a enliven_a and_o encourage_v effect_n of_o generous_a wine_n in_o a_o more_o eminent_a manner_n than_o wine_n and_o in_o the_o 10000th_o part_n of_o its_o quantity_n and_o for_o a_o long_a time_n than_o wine_n cause_v they_o shall_v diminish_v or_o disable_v the_o spirit_n for_o instance_n wine_n and_o opium_n in_o a_o due_a quantity_n but_o opium_n in_o a_o far_o less_o quantity_n as_o be_v say_v cause_v a_o pleasant_a gay_a and_o good_a humour_n courage_n bravery_n magnanimity_n promptitude_n in_o business_n expediteness_n in_o management_n serenity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n fatigue_n etc._n etc._n both_o take_v away_o sadness_n grief_n melancholy_n fear_v depression_n of_o spirit_n etc._n etc._n both_o cause_n promptitude_n to_o venery_n sine_fw-la cerere_fw-la &_o baccho_fw-la friget_fw-la venus_n so_o wine_n and_o opium_n prevent_v and_o cure_v cold_a open_v the_o pore_n promote_v perspiration_n and_o sweat_n especial_o the_o follow_a morning_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v of_o opium_n and_o be_v notorious_a as_o to_o wine_n both_o cause_n sleep_n and_o take_v away_o the_o sense_n of_o pain_n and_o require_v a_o great_a dose_n than_o ordinary_a in_o proportion_n to_o the_o pain_n both_o take_v off_o shivering_n from_o fear_n cold_a or_o ague_n fit_n and_o cause_n mirth_n contentation_n and_o acquiescence_n dryness_n of_o the_o mouth_n thirst_v a_o sense_n of_o heat_n within_o we_o a_o dream_v condition_n pleasant_a dream_n if_o the_o quantity_n of_o wine_n be_v not_o grievous_a by_o its_o heat_n load_n etc._n etc._n nocturnal_a pollution_n and_o in_o some_o constitution_n both_o cause_n vigilancy_n but_o wine_n and_o opium_n cause_v that_o more_o rare_o than_o sleep_n both_o stop_n and_o cause_n vomit_v if_o they_o stay_v too_o long_o at_o stomach_n both_o moderate_a hunger_n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d and_o be_v good_a in_o a_o canine_a appetite_n both_o cause_n swim_v in_o the_o head_n etc._n etc._n so_o both_o in_o a_o excessive_a do_v do_v cause_n at_o first_o mirth_n and_o afterward_o a_o kind_n of_o drunken_a soper_n in_o some_o in_o other_o fury_n or_o madness_n sardonick_a laughter_n and_o weight_n at_o stomach_n vomit_n hiccough_n great_a heat_n at_o stomach_n debility_n and_o laxity_n of_o all_o part_n falter_v of_o the_o tongue_n scotomy_n and_o darkness_n of_o the_o eye_n vertigo_n laxity_n of_o the_o cornea_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la deadness_n of_o the_o eye_n to_o the_o view_n loss_n of_o memory_n venereal_a fury_n a_o high_a colour_n profuse_a sweat_v purge_v sometime_o alienation_n of_o the_o mind_n loss_n of_o memory_n and_o last_o great_a or_o lesser_a effect_n according_a to_o the_o do_v constitution_n etc._n etc._n so_o a_o long_a and_o lavish_a use_n of_o both_o cause_n a_o dull_a and_o moapish_a disposition_n dropsy_n fall_v of_o humour_n upon_o weaken_v part_n a_o sleepy_a disposition_n want_v of_o appetite_n weakness_n of_o digestion_n aptitude_n to_o sterility_n and_o abortion_n early_a decrepiteness_n stoop_v in_o the_o back_n tremble_v of_o the_o hand_n weakness_n of_o memory_n shortness_n of_o life_n difficulty_n and_o danger_n in_o sudden_o leave_v they_o off_o revive_v such_o as_o sink_v for_o want_n of_o either_o and_o supply_v the_o want_n of_o each_o other_o how_o can_v any_o have_v the_o face_n to_o say_v that_o a_o thing_n which_o agree_v so_o with_o generous_a wine_n in_o effect_n can_v be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n the_o mischief_n of_o excessive_a dose_n and_o lavish_a use_n of_o either_o be_v no_o argument_n against_o their_o inspirit_a nature_n if_o it_o be_v than_o wine_n be_v no_o cordial_n though_o make_v to_o glad_a the_o heart_n
to_o disparage_v the_o performance_n as_o mean_v and_o obvious_a like_o that_o of_o the_o circulation_n of_o the_o blood_n or_o america_n when_o find_v out_o do_v not_o the_o newness_n of_o the_o thing_n the_o baffle_a endeavour_n of_o all_o mankind_n and_o the_o seem_a impossibility_n of_o ever_o find_v it_o out_o which_o be_v almost_o agree_v upon_o speak_v in_o its_o behalf_n consider_v that_o nothing_o can_v be_v plain_a and_o easy_a but_o what_o be_v true_a and_o consequent_o nothing_o valuable_a but_o what_o be_v so_o what_o be_v true_a knowledge_n but_o the_o knowledge_n of_o thing_n as_o they_o real_o be_v and_o when_o a_o thing_n be_v know_v as_o real_o as_o it_o be_v it_o must_v be_v plain_a and_o never_o so_o till_o then_o for_o to_o take_v a_o thing_n to_o be_v what_o it_o be_v not_o be_v all_o darkness_n error_n puzzle_n confusion_n and_o vanity_n as_o all_o discourse_n of_o opium_n have_v hitherto_o be_v it_o be_v no_o wonder_n then_o that_o the_o cause_n of_o the_o operation_n of_o opium_n grow_v more_o and_o more_o obscure_a while_o they_o state_v the_o cold_a quality_n of_o very_a hot_a opium_n the_o belch_a up_o of_o vulcano_n of_o fume_n from_o the_o stomach_n to_o the_o head_n which_o have_v no_o existence_n their_o act_n as_o a_o poison_n of_o the_o animal_n spirit_n their_o fix_v and_o coagulate_v they_o their_o clog_a they_o by_o adherence_n or_o cloud_v they_o their_o wedge_a themselves_o among_o the_o animal_n spirit_n none_o know_v how_o and_o thereby_o disable_n they_o their_o stuff_v the_o pore_n of_o the_o brain_n or_o compress_v it_o and_o thereby_o hinder_v the_o generation_n of_o animal_n spirit_n to_o be_v the_o cause_n of_o the_o noble_a and_o pleasant_a operation_n of_o opium_n without_o any_o foundation_n in_o nature_n or_o the_o least_o evidence_n of_o sense_n or_o reason_n but_o vain_a fantastical_a imagination_n form_v in_o the_o chimera-forges_a of_o their_o wanton_a brain_n while_o they_o endeavour_v right_o or_o wrong_n to_o appear_v considerable_a folk_n by_o do_v nothing_o to_o the_o purpose_n in_o a_o kind_n of_o pretty_a plausible_a and_o impose_v manner_n thereby_o stuff_v the_o unwary_a world_n with_o wrong_n and_o vain_a conception_n and_o impertinent_a prejudices_fw-la which_o be_v the_o great_a obstacle_n of_o knowledge_n i_o will_v fain_o know_v which_o of_o those_o hypothesise_n can_v tolerable_o solve_v 1_o in_o 10_o of_o the_o phenomena_n that_o i_o have_v enumerate_v or_o indeed_o any_o one_o phenomenon_n true_o mechanical_o and_o demonstrative_o yet_o be_v those_o whim_n the_o glorious_a production_n of_o thousand_o of_o year_n study_n and_o solicitous_a disquisition_n though_o every_o one_o that_o take_v opium_n actual_o feel_v the_o true_a cause_n of_o its_o operation_n viz._n the_o please_a delight_n that_o it_o occasion_v by_o affect_v the_o membrane_n and_o animal_n spirit_n after_o the_o manner_n that_o i_o have_v at_o large_a set_v forth_o good_a god_n what_o blund'r_a groper_n be_v mankind_n who_o daily_o feel_v the_o cause_n it_o never_o can_v find_v though_o thousand_o seek_v it_o with_o a_o eager_a mind_n chap._n xxiv_o of_o opium_n separate_v from_o its_o noxious_a part_n or_o rosin_n and_o whether_o it_o be_v a_o panacea_fw-la etc._n etc._n thus_o far_o have_v i_o speak_v of_o crude_a opium_n joint_o with_o its_o rosin_n or_o noxious_a part_n now_o i_o will_v consider_v it_o separate_v from_o it_o and_o show_v how_o to_o do_v it_o galen_n say_v that_o it_o be_v very_o difficult_a to_o find_v a_o excellent_a remedy_n without_o a_o noxious_a quality_n and_o it_o be_v as_o difficult_a to_o find_v any_o thing_n so_o noxious_a as_o not_o to_o afford_v a_o good_a medicament_n which_o you_o see_v in_o viper_n scorpion_n mercury_n etc._n etc._n all_o or_o most_o physician_n unanimous_o agree_v that_o opium_n have_v such_o a_o noxious_a quality_n that_o cause_v vomit_n hiccough_n distress_n anxiety_n convulsion_n chief_o at_o or_o about_o the_o region_n of_o the_o stomach_n and_o that_o if_o it_o be_v free_v from_o it_o it_o will_v be_v the_o noble_a of_o medicament_n who_o can_v otherwise_o imagine_v see_v it_o be_v so_o excellent_a and_o universal_a a_o remedy_n as_o it_o be_v now_o use_v in_o the_o world_n without_o such_o a_o excellent_a preparation_n thereof_o wherein_o the_o noxious_a principle_n be_v separate_v from_o it_o of_o which_o paracelsus_n say_v that_o whoever_o shall_v enjoy_v it_o will_v be_v a_o professor_n of_o no_o less_o knowledge_n than_o apollo_n machaon_n or_o podalyrius_n though_o he_o be_v the_o great_a master_n of_o arcanas_fw-la panaceas_fw-la etc._n etc._n yet_o do_v he_o confess_v that_o a_o preparation_n of_o opium_n stand_v he_o in_o stead_n and_o perform_v his_o business_n when_o all_o his_o great_a medicament_n fail_v he_o and_o that_o it_o will_v dissolve_v disease_n as_o fire_n doeâ—_n snow_n or_o use_v word_n to_o the_o same_o effect_n helmont_n be_v in_o a_o kind_n of_o rapture_n upon_o consideration_n of_o its_o excellency_n burst_v out_o into_o this_o exclamation_n happy_a be_v the_o sick_a man_n who_o physician_n know_v how_o to_o separate_v the_o deadly_a or_o noxious_a part_v from_o opium_n platerus_n affirm_v that_o he_o can_v with_o a_o preparation_n of_o opium_n preserve_v the_o break_a wheel_n of_o life_n etmuller_n say_v that_o opium_n may_v 〈◊〉_d be_v esteem_v a_o general_a remedy_n and_o the_o main_a end_n of_o his_o tract_n de_fw-fr paruis_fw-la morborum_fw-la initiis_fw-la be_v to_o show_v how_o volatiles_fw-la more_o especial_o salia-volatilia-oleosa_a as_o that_o of_o opium_n may_v in_o small_a quantity_n alter_v we_o and_o cure_v our_o disease_n it_o be_v endless_a to_o tell_v you_o the_o eulogy_n of_o the_o learned_a concern_v such_o a_o preparation_n of_o opium_n which_o they_o general_a conclude_v to_o be_v a_o most_o noble_a panacea_fw-la therefore_o many_o and_o very_o solicitous_a have_v be_v the_o disquisition_n of_o the_o ingenious_a and_o industrious_a to_o find_v out_o this_o heroic_a generous_a and_o most_o glorious_a medicament_n i_o be_o full_o satisfy_v that_o the_o pure_a sal-volatile-oleosum_a of_o opium_n due_o separate_v from_o its_o noxious_a rosin_n dross_n etc._n etc._n be_v the_o very_a thing_n some_o of_o the_o reason_n that_o convince_v i_o be_v as_o follow_v viz._n 1._o because_o opium_n have_v no_o other_o principle_n in_o it_o that_o signify_v any_o thing_n as_o to_o its_o laudable_a and_o noble_a effect_n but_o its_o sal_fw-la volatile_a oleosum_fw-la as_o have_v be_v show_v 2._o because_o the_o sal_fw-la volatile-oleosum_a of_o opium_n produce_v all_o its_o good_a effect_n 3._o because_o the_o sal-volatile-oleosum_a due_o separate_v from_o its_o rosin_n and_o other_o principle_n produce_v no_o ill_a effect_n in_o a_o moderate_a do_v this_o add_v to_o what_o have_v be_v discourse_v at_o large_a of_o the_o principle_n of_o opium_n be_v i_o think_v sufficient_a to_o satisfy_v any_o man_n that_o the_o sal-volatile-oleosum_a of_o opium_n so_o separate_v be_v the_o great_a panacea_fw-la that_o be_v seek_v for_o however_o because_o we_o be_v upon_o the_o great_a thing_n in_o physic_n as_o may_v be_v well_o infer_v from_o what_o have_v be_v already_o say_v and_o that_o the_o world_n have_v be_v under_o great_a fear_n jealousy_n and_o blindness_n concern_v this_o matter_n and_o the_o use_v of_o opium_n it_o will_v be_v well_o worth_a our_o while_n to_o give_v all_o imaginable_a satisfaction_n in_o this_o case_n therefore_o i_o will_v first_o lay_v down_o all_o the_o requisite_a qualification_n of_o a_o complete_a panacea_fw-la as_o far_o as_o i_o can_v collect_v out_o of_o the_o most_o eminent_a author_n and_o my_o own_o consideration_n thereof_o second_o i_o will_v particular_o inquire_v as_o to_o each_o of_o the_o qualification_n whether_o the_o sal_fw-la volatile-oleosum_a of_o opium_n due_o separate_v from_o every_o other_o principle_n of_o opium_n be_v furnish_v therewith_o three_o i_o will_v show_v you_o how_o due_o to_o separate_v its_o dross_n rosin_n etc._n etc._n so_o as_o to_o leave_v a_o pure_a sincere_a sal-volatile-oleosum_a of_o opium_n for_o use._n the_o requisite_a qualification_n of_o a_o panacea_fw-la be_v these_o viz._n 1._o that_o it_o shall_v high_o please_v our_o sensation_n at_o stomach_n because_o the_o stomach_n be_v contrive_v and_o appoint_v by_o god_n and_o nature_n as_o the_o touchstone_n to_o try_v a_o sentinel_n true_o to_o inform_v and_o a_o critical_a judge_n to_o determine_v what_o be_v or_o be_v not_o agreeable_a to_o our_o nature_n in_o general_a and_o therefore_o as_o have_v be_v show_v endue_v with_o a_o wonderful_a sagacity_n and_o nicety_n of_o sensation_n for_o that_o end_n it_o follow_v then_o that_o a_o panacea_fw-la shall_v be_v very_o please_v and_o agreeable_a to_o the_o stomach_n and_o therefore_o very_o cordial_a 2._o that_o it_o shall_v be_v high_o please_v to_o the_o sensitive_a soul_n which_o be_v the_o principle_n of_o all_o motion_n action_n
by_o titillation_n upon_o the_o account_n of_o the_o volatile_a salt_n which_o appear_v by_o its_o exciting_a to_o venery_n at_o the_o same_o time_n as_o all_o those_o volatiles_fw-la do_v 16._o it_o be_v cause_v vomit_n as_o it_o often_o do_v be_v a_o undoubted_a sign_n of_o its_o volatile_a salt_n for_o all_o vegetable_a vomit_n be_v such_o upon_o that_o account_n unless_o it_o be_v such_o as_o may_v move_v vomit_v mere_o by_o their_o be_v loathe_v or_o nauseated_a which_o only_o cause_v some_o particular_a person_n to_o vomit_v but_o such_o as_o be_v constant_a vomitory_n be_v so_o upon_o the_o account_n of_o their_o volatile_a salt_n as_o asaerabocea_n groundsil_n foxâ—loves_n squill_n etc._n etc._n give_v in_o a_o sufficient_a quantity_n 17._o it_o be_v lively_a effect_n as_o courage_n etc._n etc._n prove_v the_o same_o 18._o all_o author_n that_o have_v be_v curious_a do_v agree_v that_o opium_n abound_v with_o volatile_a salt_n as_o helmont_n lemery_n le_fw-fr febure_n wedelius_n and_o indeed_o every_o one_o that_o ever_o i_o read_v though_o most_o of_o they_o attribute_v its_o effect_n to_o a_o sulphur_n which_o make_v their_o testimony_n of_o its_o volatile_a salt_n the_o strong_a as_o be_v force_v to_o confess_v it_o against_o their_o hypothesise_n 19_o after_o its_o fermentation_n with_o leaven_n in_o a_o sand_n heat_v for_o 14_o day_n it_o afford_v a_o volatile_a salt_n in_o good_a quantity_n but_o mix_v with_o oil_n which_o be_v separate_v from_o it_o by_o dissolution_n in_o water_n filtring_n etc._n etc._n 20._o it_o be_v spirit_n ferment_n with_o acid_n therefore_o be_v volatile_a last_o to_o pin_n up_o all_o if_o you_o either_o chemical_o analyse_v it_o by_o fire_n or_o set_v it_o to_o crystalize_v after_o it_o be_v evaporate_v to_o a_o due_a condition_n so_o to_o do_v it_o afford_v a_o great_a quantity_n of_o volatile_a salt_n therefore_o it_o be_v pass_v all_o manner_n of_o doubt_n for_o which_o end_n i_o have_v the_o long_o and_o more_o particular_o insist_v upon_o this_o point_n that_o it_o be_v high_o impregnate_v with_o volatile_a salt_n but_o as_o i_o say_v in_o the_o last_o chapter_n it_o be_v not_o enough_o for_o it_o to_o have_v volatile_a salt_n but_o it_o must_v be_v such_o as_o exceed_v our_o own_o or_o other_o animal_n in_o activity_n briskness_n etc._n etc._n by_o reason_n of_o quantity_n or_o quality_n or_o both_o that_o it_o may_v tickle_v up_o excite_v and_o cause_v a_o fine_a and_o agreeable_a ovation_n or_o glow_v in_o our_o spirit_n which_o as_o be_v show_v be_v very_o pleasant_a as_o in_o the_o case_n of_o sem._n viril_n especial_o when_o agitate_a by_o warmth_n frication_n or_o such_o actuate_a cause_n second_o it_o manifest_o appear_v that_o the_o volatile_a salt_n of_o opium_n exceed_v we_o in_o activity_n briskness_n etc._n etc._n 1._o by_o its_o exulcerate_v or_o blister_v quality_n especial_o if_o it_o be_v very_o good_a opium_n 2._o by_o its_o psilothrick_n quality_n to_o cause_v the_o hair_n to_o shed_v 3._o by_o its_o irritate_v to_o venery_n in_o so_o eminent_a a_o degree_n as_o cantharides_n bee_n pismire_n etc._n etc._n do_v and_o even_o beyond_o the_o ordinary_a course_n of_o sem._n virile_a which_o be_v most_o saturate_v with_o volatile_a salt_n of_o any_o part_n of_o the_o animal_n as_o appear_v by_o its_o dissolution_n like_o opium_n in_o watery_a menstruum_n its_o rank_a smell_n its_o titillate_v to_o venery_n its_o weight_n etc._n etc._n which_o be_v much_o the_o same_o with_o that_o of_o opium_n both_o sink_v in_o water_n etc._n etc._n 4._o by_o its_o great_a irritation_n to_o make_v water_n like_o cantharides_n bee_n pismire_n millepedes_n etc._n etc._n when_o it_o be_v take_v in_o a_o good_a quantity_n or_o often_o 5._o by_o its_o cause_v vomit_n in_o a_o very_a severe_a manner_n which_o it_o will_v not_o do_v without_o a_o very_a poignant_a volatile_a salt_n 6._o by_o its_o cause_v such_o violent_a itch_n in_o the_o skin_n especial_o if_o take_v in_o any_o quantity_n after_o it_o have_v pass_v all_o digestion_n and_o concoction_n and_o 7._o by_o its_o cause_v acrimonious_a sweat_v after_o it_o have_v pass_v those_o digestion_n and_o concoction_n 8._o by_o its_o cause_v a_o very_a pleasant_a sensation_n at_o stomach_n far_o above_o any_o flesh_n jelly_n or_o any_o animal_n nutriment_n 9_o by_o its_o offend_v the_o eye_n so_o much_o by_o its_o acrimony_n as_o mustard_n onion_n horse_n radish_n etc._n etc._n do_v 10._o by_o its_o very_a pungent_a and_o acrimonious_a taste_n above_o all_o flesh_n or_o fish_n 11._o by_o its_o very_a rank_n and_o vehement_a scent_n equal_a to_o if_o not_o exceed_v that_o of_o semen_n virile_a 12._o by_o its_o chemical_a analysis_n whereby_o it_o afford_v a_o very_a acrimonious_a volatile_a salt_n in_o great_a plenty_n which_o helmont_n wedelius_n and_o other_o do_v confirm_v therefore_o it_o be_v also_o past_a doubt_n that_o the_o volatile_a salt_n of_o opium_n be_v more_o active_a acrimonious_a and_o titillate_v than_o those_o in_o our_o membrane_n or_o in_o sem._n virile_a itself_o but_o see_v it_o be_v not_o volatile_a salt_n alone_o as_o be_v show_v which_o agree_v only_o with_o one_o of_o the_o active_a principle_n of_o our_o membrane_n and_o may_v be_v and_o be_v of_o itself_o too_o acrimonious_a and_o rude_a for_o the_o membrane_n without_o its_o be_v sweeten_v up_o and_o smooth_v into_o a_o more_o gentle_a and_o please_a agreeableness_n by_o oily_a part_n we_o must_v see_v whether_o it_o be_v not_o also_o oily_a or_o sulphureous_a and_o consequent_o a_o sal-volatile-oleosum_a agree_v in_o both_o the_o active_a principle_n of_o our_o membrane_n that_o it_o may_v thereby_o be_v the_o more_o delectable_a gentle_a and_o agreeable_a three_o it_o be_v very_o obvious_a and_o evident_a that_o opium_n be_v sulphureous_a 1._o because_o the_o juice_n of_o the_o poppy_n whereof_o it_o be_v make_v be_v of_o itself_o when_o it_o drop_n out_o of_o the_o incision_n milkwhite_a which_o colour_n in_o liquid_n especial_o the_o juice_n of_o plant_n proceed_v from_o sulphureous_a particle_n mix_v with_o water_n or_o phlegm_n as_o milk_n emulsion_n chyle_n cinnamon_n water_n and_o the_o tincture_n of_o all_o sulphureous_a thing_n drop_v into_o water_n do_v evince_n 2._o because_o it_o be_v inflammable_a for_o nothing_o be_v so_o but_o what_o be_v sulphureous_a 3._o because_o opium_n will_v soften_v with_o a_o dry_a warmth_n which_o all_o and_o only_o sulphureous_a thing_n will_v do_v as_o all_o rosin_n tallow_n pitch_v turpentine_n oil_n and_o such_o sulphureous_a thing_n 4._o because_o it_o be_v very_o bitter_a and_o that_o oleose_a particle_n be_v always_o as_o dr._n grow_v and_o silvius_n true_o say_v one_o ingredient_n of_o a_o bitter_a taste_n 5._o it_o be_v tawny_a colour_n do_v also_o as_o be_v say_v according_a to_o dr._n grow_v argue_v much_o sulphur_n 6._o it_o be_v hot_a taste_n prove_v the_o same_o for_o a_o proper_a hot_a taste_n be_v from_o sulphur_n as_o the_o bite_n or_o pungent_a be_v from_o volatile_a salt_n 7._o because_o of_o its_o pungent_a and_o strong_a smell_n which_o denote_v sulphur_n 8._o it_o be_v be_v so_o dissolvable_a as_o it_o be_v in_o spirit_n of_o wine_n brandy_n and_o other_o sulphureous_a menstruum_n prove_v the_o same_o 9_o it_o be_v dissolve_v quality_n argue_v that_o it_o have_v the_o same_o principle_n with_o our_o skin_n and_o flesh_n which_o be_v oleose_v as_o well_o as_o salino-volatile_a and_o that_o nothing_o be_v a_o complete_a dissolver_n but_o such_o as_o have_v both_o because_o agreeableness_n in_o principle_n be_v the_o basis_n of_o dissolution_n as_o you_o see_v in_o menstruum_n and_o the_o thing_n therein_o dissolve_v there_o be_v no_o good_a kind_a or_o complete_a dissolvent_a of_o our_o flesh_n etc._n etc._n but_o what_o participate_v of_o both_o because_o otherwise_o there_o will_v be_v a_o disagreement_n in_o one_o respect_n 10._o it_o appear_v by_o autopsie_n upon_o the_o chemical_a analysis_n of_o opium_n etc._n etc._n that_o it_o have_v a_o very_a considerable_a quantity_n of_o sulphur_n 11._o so_o if_o you_o only_o dissolve_v it_o in_o water_n you_o will_v find_v much_o sulphureous_a substance_n undissolved_a at_o the_o bottom_n 12._o all_o or_o most_o of_o the_o modern_a author_n attribute_v its_o operation_n to_o sulphur_n agree_v that_o it_o be_v well_o impregnate_v therewith_o therefore_o opium_n consist_v very_o much_o as_o to_o its_o active_a principle_n of_o a_o sal-volatile-sulphureum_a but_o still_o this_o do_v not_o complete_a a_o most_o agreeable_a sal-volatile-oleosum_a 1._o because_o it_o may_v be_v a_o sal-volatile-resinosum_a and_o yet_o be_v a_o sal-volatile-sulphureum_a 2._o if_o it_o be_v a_o sal-volatile-oleosum_a the_o oil_n and_o the_o volatile_a salt_n may_v be_v so_o disjoin_v as_o not_o to_o conspire_v and_o cooperate_v to_o please_v the_o membrane_n but_o act_n separately_z as_o oil_n and_o volatile_a salt_n give_v out_o of_o divers_a
spoon_n and_o cause_n no_o more_o effect_n than_o oil_n of_o olive_n and_o spirit_n of_o sal_fw-la amenoniack_a take_v inward_o one_o act_v too_o soft_o lazy_o and_o greasy_o to_o cause_v any_o brisk_a and_o agreeable_a ovation_n of_o the_o spirit_n and_o the_o other_o too_o rude_o sting_v the_o membrane_n therefore_o we_o must_v proceed_v in_o our_o enquiry_n four_o opium_n have_v a_o sort_n of_o resinous_n sulphur_n that_o be_v loose_a and_o not_o unite_v with_o the_o volatile_a salt_n which_o plain_o appear_v 1._o because_o if_o you_o dissolve_v opium_n in_o water_n cold_a or_o hot_a or_o any_o watery_a menstruum_fw-la you_o will_v find_v a_o good_a quantity_n of_o rosin_n undissolved_a at_o bottom_n while_o the_o volatile_a salt_n be_v all_o or_o most_o dissolve_v in_o the_o water_n especial_o if_o the_o water_n be_v often_o repeat_v and_o quite_o separate_v from_o the_o resinous_n part_v which_o subside_v without_o any_o more_o trouble_n which_o show_v that_o the_o volatile_a salt_n and_o it_o be_v not_o combine_v but_o in_o a_o very_a loose_a and_o distinct_a manner_n 2._o because_o if_o you_o first_o dissolve_v opium_n in_o spirit_n of_o wine_n which_o imbibe_v the_o rosin_n it_o be_v easy_o again_o precipitate_v by_o plain_a water_n leave_v behind_o it_o all_o or_o most_o of_o the_o volatile_a salt_n in_o the_o form_n of_o a_o red_a tincture_n in_o the_o menstruum_fw-la as_o it_o do_v also_o in_o the_o former_a case_n note_v that_o the_o resinous_n part_n of_o opium_n have_v no_o effect_n as_o a_o opiate_n for_o if_o it_o be_v well_o wash_v with_o water_n as_o be_v say_v it_o have_v no_o operation_n of_o that_o kind_n or_o so_o little_a that_o it_o be_v not_o worth_a the_o mind_v but_o all_o the_o virtue_n specific_a taste_n smell_v etc._n etc._n be_v carry_v away_o in_o that_o red_a tincture_n which_o have_v all_o the_o good_a effect_n of_o opium_n as_o experience_n assure_v we_o 3._o because_o if_o opium_n be_v very_o much_o torrefy_v most_o of_o the_o volatile_a salt_n be_v evaporate_v and_o with_o it_o most_o if_o not_o all_o the_o virtue_n of_o opium_n but_o the_o rosin_n remain_v as_o a_o deadish_a stuff_n in_o respect_n of_o the_o good_a effect_n of_o opium_n though_o it_o be_v as_o shall_v be_v prove_v the_o producer_n of_o the_o ill_a effect_n thereof_o therefore_o this_o rosin_n must_v be_v whole_o reject_v five_o the_o red_a tincture_n aforesaid_a have_v all_o or_o most_o of_o the_o volatile_a salt_n in_o it_o 1._o because_o water_n be_v the_o proper_a menstruum_fw-la for_o saline_n thing_n and_o that_o the_o tincture_n reduce_v to_o a_o extract_n give_v very_o much_o in_o moist_a wether_n which_o quality_n it_o must_v have_v from_o the_o volatile_a salt_n because_o it_o have_v very_o little_o fix_v salt_n 2._o because_o the_o specific_a bitterness_n which_o proceed_v from_o volatile_a salt_n and_o oily_a part_n be_v whole_o in_o that_o red_a tincture_n 3._o because_o that_o tincture_n have_v also_o the_o specific_a rankness_n of_o smell_n that_o the_o volatile_a salt_n as_o be_v show_v give_v the_o opium_n by_o the_o help_n of_o some_o oily_a part_n 4._o because_o that_o tincture_n reduce_v to_o a_o extract_n have_v the_o bite_a taste_n of_o opium_n which_o as_o be_v show_v proceed_v from_o its_o volatile_a salt_n 5._o because_o that_o extract_n incides_fw-la discuss_n resolve_n be_v psilothrick_n titillate_n to_o venery_n cause_v itch_n in_o the_o skin_n acrimonious_a sweat_v etc._n etc._n all_o which_o be_v as_o be_v show_v the_o effect_n of_o volatile_a salt_n but_o what_o need_v i_o insist_v so_o much_o upon_o its_o effect_n to_o prove_v it_o when_o 6._o it_o appear_v by_o crystalization_n of_o the_o say_a tincture_n after_o it_o have_v be_v evaporate_v to_o a_o due_a degree_n that_o it_o contain_v the_o volatile_a salt_n in_o it_o which_o in_o a_o cool_a place_n shoot_v to_o elegant_a crystal_n and_o that_o 7._o it_o be_v find_v therein_o by_o chemical_a operation_n by_o fire_n six_o the_o say_a tincture_n be_v oleose_v 1._o because_o the_o redness_n of_o the_o tincture_n must_v be_v from_o oily_a part_n for_o pure_a sincere_a volatile_a salt_n give_v no_o such_o tincture_n 2._o because_o it_o be_v bitter_a one_o ingredient_n of_o which_o taste_n be_v ever_o oily_a part_n as_o be_v say_v 3._o because_o of_o its_o rank_a smell_n like_o sem._n viril_n which_o prove_v it_o to_o be_v sulphureous_a for_o the_o volatile_a salt_n alone_o have_v only_o a_o quick_a smell_n or_o urinous_a at_o far_a 4._o because_o it_o be_v of_o a_o hot_a taste_n when_o reduce_v to_o a_o extract_n which_o heat_v of_o taste_n consider_v distinct_o from_o its_o pungent_a or_o bite_a taste_n must_v be_v from_o sulphureous_a or_o oily_a part_n 5._o because_o spirit_n of_o wine_n and_o other_o spirituosulphureous_a menstruum_n do_v ready_o dissolve_v it_o when_o reduce_v to_o a_o extract_n 6._o because_o the_o extract_n soften_v with_o dry_a warmth_n as_o sulphureous_a or_o oily_a thing_n do_v 7._o because_o a_o true_a sal-volatile-oleosum_a wherein_o the_o volatile_a salt_n and_o oily_a part_n be_v intimate_o combine_v as_o you_o find_v in_o all_o blood_n tincture_n of_o several_a plant_n that_o have_v such_o a_o sal-volatile-oleosum_a be_v red_a 8._o because_o it_o can_v not_o otherwise_o so_o fine_o please_v the_o membrane_n cause_n sleep_n compose_v the_o spirit_n etc._n etc._n if_o it_o be_v all_o volatile_a salt_n which_o be_v whole_o pungent_a and_o acrimonious_a mighty_o oppose_v sleep_n and_o cause_v a_o great_a stir_n in_o the_o blood_n and_o spirit_n but_o as_o i_o say_v as_o to_o its_o volatile_a salt_n what_o need_v i_o insist_v upon_o its_o effect_n when_o 10._o it_o be_v inflammability_n after_o it_o be_v reduce_v to_o a_o extract_n and_o dry_v put_v it_o out_o of_o all_o question_n and_o that_o 11._o a_o oil_n may_v be_v separate_v from_o the_o volatile_a salt_n though_o not_o without_o trouble_n because_o that_o as_o be_v requisite_a to_o complete_a it_o in_o the_o high_a degree_n seven_o the_o oily_a part_n and_o volatile_a salt_n be_v very_o intimate_o and_o strict_o combine_v as_o fair_o appear_v 1._o by_o the_o difficulty_n to_o separate_v they_o 2._o by_o the_o redness_n of_o the_o tincture_n as_o in_o blood_n etc._n etc._n for_o when_o oily_a or_o sulphureous_a particle_n be_v loose_a therein_o they_o make_v either_o a_o white_a colour_n as_o the_o rosin_n do_v in_o the_o drop_n that_o fall_v out_o of_o the_o incision_n in_o the_o head_n of_o the_o poppy_n which_o be_v milk_n white_a or_o leave_v the_o volatile_a spirit_n perspicuous_a as_o in_o a_o sort_n of_o artificial_a sal._n volatile-oleosum_a that_o be_v sell_v at_o the_o apothecary_n shop_n in_o london_n 3._o because_o it_o impart_v its_o tincture_n which_o depend_v upon_o both_o to_o all_o menstruum_n 4._o because_o it_o impart_v its_o virtue_n which_o depend_v upon_o both_o to_o all_o menstruum_n 5._o because_o it_o impart_v its_o specific_a smell_n which_o depend_v upon_o both_o to_o all_o menstruumt_v 6._o because_o it_o impart_v its_o specific_a hot_a and_o bite_a taste_n which_o depend_v upon_o both_o the_o oily_a and_o volatile_a particle_n to_o all_o menstruum_n 7._o because_o it_o will_v hold_v its_o virtue_n many_o year_n which_o it_o can_v not_o if_o the_o volatile_a salt_n and_o oily_a part_n be_v not_o very_o strict_o combine_v 8._o because_o that_o notwithstanding_o the_o digestion_n at_o stomach_n it_o have_v hold_v its_o specific_a virtue_n smell_v and_o taste_n after_o it_o have_v be_v in_o it_o 4_o 5_o 6_o 7_o 8_o 9_o 10_o 11_o 12_o 18_o or_o more_o hour_n as_o appear_v by_o its_o operate_n so_o long_o and_o afteward_n its_o be_v vomit_v up_o with_o the_o same_o taste_n and_o smell_v that_o it_o have_v at_o first_o than_o which_o there_o can_v be_v a_o great_a argument_n 9_o because_o it_o have_v be_v carry_v off_o by_o stool_n which_o have_v its_o specific_a smell_n after_o many_o hour_n remain_v in_o the_o stomach_n 10._o because_o its_o operation_n in_o general_n last_v long_o charas_fw-la mention_n one_o that_o it_o operate_v with_o for_o about_o 30_o hour_n and_o wedelius_n another_o who_o opium_n cause_v to_o vomit_v constant_o about_o 18_o hour_n after_o it_o be_v take_v 11._o because_o it_o have_v its_o effect_n upon_o the_o venereal_a membrane_n after_o it_o have_v pass_v the_o digestion_n at_o stomach_n the_o effect_n of_o the_o choler_n and_o succus_fw-la pancreatus_fw-la in_o the_o duodenum_fw-la be_v strain_v through_o the_o coat_n of_o the_o intestine_n into_o the_o lacteal_v and_o through_o the_o glandule_n of_o the_o mesentery_n mix_v and_o circulate_v with_o the_o blood_n etc._n etc._n 12._o because_o after_o all_o that_o it_o have_v its_o effect_n upon_o the_o skin_n by_o cause_v a_o itch_a therein_o 13._o because_o it_o not_o only_a cause_n acrimonious_a sweat_v but_o such_o as_o evident_o smell_v thereof_o
hitherto_o but_o meet_v groundless_a and_o fantastic_a imagination_n objection_n some_o may_v say_v for_o the_o folly_n of_o the_o world_n be_v great_a why_o shall_v not_o a_o extract_v out_o of_o spirit_n of_o wine_n be_v good_a for_o since_o wine_n correct_v it_o much_o more_o shall_v spirit_n of_o wine_n do_v it_o by_o its_o more_o active_a sulphureous_a spirit_n answer_n so_o it_o will_v if_o you_o pour_v it_o upon_o it_o in_o the_o stomach_n or_o a_o digest_v pot_n for_o than_o it_o will_v much_o contribute_v to_o its_o division_n digestion_n and_o take_v off_o its_o viscidity_n as_o spirit_n of_o wine_n do_v in_o any_o vessel_n wherein_o you_o pour_v it_o upon_o rosin_n but_o it_o be_v quite_o another_o matter_n when_o reduce_v and_o rounit_v into_o the_o form_n of_o a_o extract_v again_o and_o all_o the_o spirit_n of_o wine_n evaporate_v or_o otherwise_o separate_v from_o it_o for_o then_o the_o resinous_n part_n be_v in_o statu_fw-la quo_fw-la of_o coalescence_n and_o want_v to_o be_v separate_v by_o wine_n or_o spirit_n of_o wine_n lixivial_o yolk_n of_o a_o egg_n etc._n etc._n as_o much_o as_o ever_o obj._n it_o may_v be_v say_v that_o the_o rosin_n of_o opium_n be_v but_o as_o other_o rosin_n therefore_o why_o shall_v it_o offend_v so_o much_o in_o the_o case_n of_o opium_n ans._n for_o three_o very_a manifest_a reason_n 1._o that_o it_o be_v a_o rosin_n of_o a_o peculiar_a clamminess_n and_o viscidity_n 2._o that_o it_o have_v acrimony_n in_o it_o as_o appear_v by_o its_o purge_v quality_n if_o it_o be_v give_v in_o any_o quantity_n and_o that_o the_o stomach_n dissolve_v it_o as_o be_v show_v 3._o that_o it_o be_v join_v with_o the_o pungent_a particle_n of_o the_o volatile_a salt_n of_o the_o opium_n which_o when_o it_o stick_v to_o the_o stomach_n it_o hold_v to_o it_o tear_v it_o too_o long_a and_o continual_o with_o those_o point_n upon_o the_o same_o part_n which_o must_v cause_v distress_n and_o vomit_n in_o weak_a stomach_n that_o can_v digest_v it_o and_o that_o sometime_o to_o no_o purpose_n whereupon_o follow_v convulsion_n hiccough_n etc._n etc._n and_o all_o endeavour_n fall_v a_o yield_v or_o succumbency_n follow_v by_o faint_n syncopes_fw-la leipothymy_n etc._n etc._n and_o sometime_o death_n itself_o for_o it_o must_v be_v a_o most_o grievous_a thing_n to_o be_v so_o continual_o sting_v in_o the_o same_o part_n of_o the_o most_o sensile_a membrane_n of_o the_o stomach_n without_o remedy_n or_o redress_n if_o some_o have_v die_v of_o a_o little_a gum_n ammoniacum_n or_o sagapenum_n stick_v to_o the_o intestinum_fw-la rectum_fw-la or_o colon_n which_o be_v the_o sink_v of_o the_o body_n and_o fit_v for_o and_o use_v to_o bear_v all_o faeces_fw-la and_o trash_n much_o more_o must_v the_o nice_a and_o exquisite_o dispose_v membrane_n at_o stomach_n be_v grieve_v by_o such_o point_a rosin_n as_o that_o of_o opium_n stick_v to_o some_o part_n thereof_o beside_o that_o the_o stomach_n do_v peculiarly_a hate_n and_o loath_a that_o any_o thing_n how_o gentle_a soever_o shall_v stay_v too_o long_o in_o it_o which_o create_v frequent_a and_o sad_a disturbance_n in_o such_o who_o stomach_n be_v relax_v as_o it_o be_v also_o in_o the_o case_n of_o opium_n and_o not_o in_o due_a time_n discharge_v themselves_o of_o the_o grieve_v matter_n therefore_o such_o as_o be_v most_o trouble_v with_o those_o dismal_a symptom_n after_o resinous_n opium_n be_v people_n that_o have_v fine_a texture_n and_o ill_a digestion_n with_o who_o it_o must_v and_o do_v deal_v for_o a_o good_a while_n as_o a_o pleaser_n of_o the_o stomach_n till_o the_o indigestible_a rosin_n that_o be_v stick_v to_o it_o do_v therefore_o and_o because_o it_o hold_v the_o point_n of_o the_o volatile_a salt_n so_o tedious_o and_o importunate_o to_o one_o parâ—_n grievous_o teaz_v and_o urge_v the_o stomach_n to_o vomit_v etc._n etc._n which_o it_o do_v in_o some_o soon_o in_o other_o late_a according_a to_o their_o respective_a disposition_n of_o stomach_n hence_o it_o be_v that_o it_o operate_v pleas_o in_o some_o for_o several_a hour_n before_o it_o excite_v a_o nausea_n etc._n etc._n viz._n 3_o 4_o 5_o 6_o 7_o 8_o 9_o 10_o 11_o 12_o 13_o 14_o 15_o 16_o 17_o 18_o and_o more_o hour_n and_o in_o such_o as_o have_v a_o sturdy_a texture_n and_o strong_a digestion_n operate_v only_a pleas_o all_o the_o time_n because_o their_o sensation_n be_v not_o so_o nice_a and_o that_o they_o gradual_o digest_v the_o rosin_n which_o if_o the_o opium_n be_v give_v in_o a_o large_a do_v do_v as_o rosin_n dissolve_v be_v apt_a to_o do_v especial_o if_o they_o have_v any_o acrimony_n as_o this_o have_v turn_v into_o a_o purger_n which_o bring_v down_o ordure_n that_o smell_v of_o the_o opium_n and_o so_o the_o danger_n be_v over_o how_o common_a be_v it_o that_o vomitory_n be_v much_o subdue_v in_o some_o stomach_n turn_v to_o be_v purger_n thus_o it_o happen_v with_o dog_n that_o have_v a_o robu_v texture_n and_o strong_a digestion_n but_o such_o resinous_n opium_n deal_v severe_o with_o cat_n and_o common_o kill_v they_o you_o may_v see_v from_o the_o premise_n why_o it_o cause_v ill_a symptom_n often_o in_o woman_n and_o child_n than_o in_o man_n and_o in_o fine_a textured_a man_n than_o the_o robu_v and_o in_o such_o as_o have_v weak_a digestion_n rather_o than_o in_o they_o that_o have_v strong_a why_o it_o cause_v all_o the_o symptom_n of_o please_a sensation_n at_o first_o and_o the_o ill_a effect_n afterward_o why_o some_o have_v no_o ill_a effect_n after_o it_o even_o in_o a_o large_a quantity_n unless_o you_o will_v call_v purge_v a_o ill_a effect_n why_o such_o as_o purge_v after_o a_o great_a do_v escape_v the_o danger_n as_o dog_n etc._n etc._n why_o their_o vomit_n especial_o the_o first_o smell_v etc._n etc._n of_o the_o opium_n though_o the_o vomit_v happen_v after_o many_o hour_n why_o the_o vomit_n be_v so_o very_o tedious_a and_o severe_a viz._n because_o of_o the_o stubborn_a adherence_n of_o the_o rosin_n to_o the_o stomach_n why_o it_o operate_v so_o long_a a_o time_n in_o some_o in_o comparison_n of_o other_o viz._n by_o stay_v so_o long_o at_o stomach_n 1._o all_o which_o seem_v to_o i_o a_o good_a argument_n that_o such_o as_o die_v with_o opium_n die_v while_o it_o be_v at_o stomach_n and_o consequent_o because_o of_o the_o rosin_n which_o must_v needs_o be_v fatal_a in_o great_a dose_n see_v it_o be_v sometime_o so_o very_o grievous_a in_o dose_n of_o a_o grain_n or_o two_o that_o bring_v people_n even_o to_o death_n door_n with_o vomit_n distress_n syncopes_fw-la etc._n etc._n yea_o and_o have_v kill_v some_o even_o in_o that_o small_a quantity_n as_o i_o be_o inform_v 2._o some_o evident_o die_v while_o it_o be_v at_o stomach_n because_o they_o die_v soon_o after_o they_o vomit_v up_o somewhat_o that_o smell_v of_o it_o though_o possible_o the_o rosin_n still_o stick_v to_o it_o 3._o because_o other_o evident_o die_v of_o the_o vomit_v and_o its_o plain_a effect_n at_o stomach_n 4._o because_o they_o common_o die_v with_o a_o hiâ—eough_n 5._o man_n die_v of_o it_o within_o the_o usual_a time_n that_o it_o stay_v at_o stomach_n which_o be_v sometime_o 20_o hour_n for_o certain_a whatever_o more_o it_o may_v be_v when_o large_a dose_n be_v take_v and_o to_o i_o it_o seem_v a_o argument_n of_o its_o kill_n at_o stomach_n when_o they_o die_v after_o 20_o hour_n because_o if_o it_o do_v not_o stick_v at_o stomach_n all_o that_o time_n the_o operation_n must_v have_v be_v over_o or_o at_o least_o much_o decline_v and_o consequent_o the_o height_n of_o the_o danger_n past_a 6._o i_o can_v find_v that_o any_o have_v die_v of_o opium_n when_o the_o rosin_n be_v separate_v from_o it_o though_o i_o do_v not_o deny_v but_o that_o it_o may_v kill_v then_o as_o a_o immoderate_a quantity_n of_o wine_n have_v do_v but_o this_o i_o can_v tell_v that_o one_o do_v at_o mr._n bank_n the_o chemist_n in_o walbrook_n in_o the_o city_n of_o london_n drink_v as_o mr._n banks_n inform_v i_o a_o pint_n and_o a_o half_n of_o such_o a_o liquid_a preparation_n of_o opium_n that_o have_v the_o rosin_n separate_v from_o it_o that_o have_v the_o power_n of_o 3_o ounce_n of_o opium_n in_o it_o and_o it_o never_o harm_v nor_o discompose_v he_o but_o that_o he_o vomit_v about_o a_o hour_n after_o it_o be_v take_v whether_o he_o do_v so_o by_o reason_n of_o the_o opium_n or_o because_o the_o person_n be_v cropsick_a as_o they_o call_v it_o by_o reason_n he_o have_v drink_v much_o wine_n before_o or_o both_o i_o can_v determine_v now_o i_o hope_v that_o my_o inquisitive_a reader_n be_v full_o satisfy_v 1._o that_o opium_n do_v not_o act_n by_o a_o cold_a quality_n nor_o by_o the_o mean_n of_o fume_n nor_o any_o how_o
by_o diminish_v or_o disable_n the_o spirit_n except_o it_o be_v that_o the_o pernicious_a rosin_n may_v do_v something_o of_o that_o kind_n by_o its_o aforesaid_a ill_a effect_n but_o by_o pleasant_o affect_v the_o membrane_n at_o stomach_n venereal_a part_n etc._n etc._n 2._o that_o sleep_n be_v cause_v by_o relaxation_n and_o quiet_v the_o spirit_n 3._o that_o pleasure_n especial_o if_o intense_a and_o last_a as_o that_o by_o opium_n comfort_n enlivens_fw-la encourage_v and_o cause_v a_o ovation_n of_o the_o sensitive_a soul_n and_o spirit_n and_o displeasure_n cause_v sadness_n dejection_n etc._n etc._n 4._o how_o pleasure_n must_v cause_v complacency_n satisfaction_n content_a acquiescence_n and_o composure_n of_o the_o sensitive_a soul_n and_o spirit_n as_o grievance_n cause_v the_o contrary_n 5._o how_o pleasure_n elevate_a and_o keep_v up_o the_o spirit_n and_o cause_v a_o entire_a relaxation_n of_o the_o defensive_a and_o a_o great_a relaxation_n of_o the_o vigilative_a contraction_n which_o tire_v the_o sensitive_a soul_n must_v cause_v euphory_n or_o easy_a undergo_n of_o labour_n journey_n etc._n etc._n without_o lassitude_n as_o experience_n show_v 6._o how_o pleasure_n cause_v relaxation_n of_o all_o the_o sensile_a part_n 7._o how_o the_o say_a relaxation_n as_o in_o sleep_n do_v by_o suffer_v the_o animal_n spirit_n to_o expand_v and_o thereby_o make_v they_o unfit_a to_o carry_v impression_n smart_o which_o be_v necessary_a to_o convey_v a_o sense_n of_o pain_n for_o a_o smart_a impression_n be_v the_o very_a cause_n of_o it_o take_v away_o pain_n to_o which_o you_o may_v add_v that_o the_o sensitive_a soul_n attend_v willing_o to_o the_o sense_n of_o pleasure_n be_v divert_v from_o pain_n and_o that_o a_o sense_n of_o pain_n can_v be_v in_o the_o same_o subject_a with_o pleasure_n which_o be_v therefore_o once_o excite_v pain_n must_v disappear_v but_o that_o of_o take_v away_o all_o smartness_n of_o impression_n by_o relaxation_n be_v a_o plain_a mechanical_a cause_n 8._o how_o therefore_o all_o flux_n that_o be_v cause_v by_o or_o require_v a_o grievous_a sensation_n or_o irritation_n by_o quantity_n or_o quality_n to_o maintain_v and_o continue_v they_o by_o cause_v a_o contraction_n of_o the_o part_n to_o squeeze_v out_o the_o humour_n must_v be_v moderate_v for_o want_v of_o sensation_n upon_o such_o relaxation_n to_o irritate_fw-la the_o part_n as_o it_o happen_v in_o sleep_n or_o in_o any_o case_n where_o relaxation_n and_o thereby_o expansion_n of_o the_o animal_n spirit_n incapacitates_fw-la they_o to_o carry_v impression_n smart_o which_o be_v of_o the_o essence_n of_o pain_n as_o have_v be_v show_v 9_o how_o perspiration_n must_v be_v promote_v by_o relaxation_n which_o open_v the_o pore_n 10._o how_o that_o by_o the_o same_o mean_n sweat_v also_o must_v be_v promote_v if_o the_o body_n be_v full_a of_o moisture_n 11._o how_o opium_n or_o semen_n animale_a be_v of_o the_o same_o principle_n and_o of_o like_a principle_n with_o cantharides_n pismire_n bee_n garlick_n etc._n etc._n must_v excite_v to_o venery_n cause_n itch_n of_o the_o skin_n etc._n etc._n 12._o how_o opium_n may_v by_o too_o high_a a_o ovation_n of_o the_o spirit_n cause_n watch_v while_o pleasure_n cause_v relaxation_n etc._n etc._n may_v take_v away_o pain_n for_o relaxation_n as_o in_o sleep_n syncopes_fw-la etc._n etc._n be_v enough_o to_o take_v away_o pain_n but_o to_o sleep_v quietness_n of_o the_o spirit_n be_v also_o require_v as_o well_o as_o their_o expansion_n by_o relaxation_n so_o that_o pain_n may_v very_o well_o be_v take_v off_o without_o sleep_n as_o it_o often_o be_v by_o opium_n that_o always_o relax_n 13._o how_o the_o pleasure_n that_o opium_n cause_n be_v as_o be_v say_v by_o the_o same_o principle_n and_o therefore_o of_o the_o same_o nature_n with_o that_o which_o animal_n seed_n cause_v upon_o the_o membrane_n but_o that_o animal_n seed_n cause_v it_o only_o upon_o one_o part_n and_o opium_n upon_o the_o membrane_n of_o the_o stomach_n venereal_a part_n and_o all_o other_o in_o general_n and_o that_o only_a for_o a_o moment_n but_o this_o of_o opium_n for_o many_o hour_n by_o which_o mean_v the_o effect_n of_o relaxtion_n by_o pleasure_n come_v to_o be_v more_o remarkable_a as_o after_o much_o wine_n who_o effect_n be_v somewhat_o last_v and_o internal_a as_o that_o of_o opium_n be_v 14._o how_o the_o rosin_n of_o opium_n cause_v its_o ill_a effect_n by_o its_o indigestibleness_n adhere_v quality_n and_o tedious_a sting_a of_o the_o exquisite_o nice_a coat_n of_o the_o stomach_n by_o continual_o teaze_v and_o urge_v it_o by_o its_o actimony_n and_o acute_a volatile_a point_n or_o spiculâ—_n therefore_o have_v 1._o a_o most_o perfect_a and_o complete_a sol-volatile-oleosum_a in_o opium_n of_o the_o same_o please_a principle_n as_o to_o all_o membrane_n as_o animal_n seed_n be_v to_o the_o membrane_n of_o venus_n whereby_o they_o must_v be_v please_v tickle_v and_o relax_v 2._o a_o pernicious_a rosin_n indigestible_a stick_v and_o arm_v with_o acrimonious_a and_o sting_a point_n which_o must_v high_o offend_v the_o most_o sensile_a coat_n at_o the_o stomach_n i_o be_o now_o ready_a by_o god_n assistance_n to_o explain_v every_o phenomenon_n or_o effect_v of_o opium_n however_o amaze_a and_o mysterious_a hope_v they_o will_v not_o remain_v long_o so_o chap._n xvi_o the_o explication_n of_o the_o effect_n of_o opium_n use_v external_o its_o effect_n external_o use_v be_v of_o two_o sort_n either_o i._o as_o a_o opiate_n or_o please_a tickler_n of_o the_o membrane_n or_o ii_o as_o a_o alterative_a of_o the_o part_n that_o it_o be_v apply_v to_o first_o as_o a_o opiate_n or_o pleaser_n of_o the_o membrane_n it_o have_v the_o same_o effect_n as_o opium_n use_v internal_o and_o for_o the_o same_o reason_n therefore_o the_o cause_n of_o its_o operation_n in_o this_o case_n will_v be_v better_o see_v by_o the_o explication_n of_o its_o internal_a effect_n which_o be_v far_o more_o perfect_a complete_a and_o certain_a second_o as_o a_o alterative_a of_o the_o part_n that_o it_o be_v apply_v to_o which_o be_v the_o follow_v viz._n 1._o it_o incides_fw-la resolve_n and_o discuss_n by_o its_o point_a penetrate_a and_o volatile_a salt_n insinuate_v itself_o into_o the_o part_n and_o humour_n of_o the_o animal_n because_o its_o particle_n be_v fine_a minute_n and_o agreeable_a thereto_o as_o menstruum_n to_o the_o thing_n to_o be_v dissolve_v then_o by_o its_o volatility_n it_o discuss_n what_o it_o have_v so_o incide_v and_o resolve_v 2._o it_o mollefy_v and_o relax_n by_o its_o sal-volatile-oleosum_a so_o resolve_v the_o part_n and_o humour_n and_o thereby_o kindly_a loosen_a they_o thus_o opiate_n as_o solanum_fw-la lethale_n or_o deadly_a night_n shade_n hemlock_n mandrake_n etc._n etc._n come_v to_o be_v of_o excellent_a use_n in_o hard_a tumor_n of_o the_o spleen_n tophousness_n etc._n etc._n 3._o it_o maturate_v and_o suppurate_v for_o the_o aforesaid_a reason_n for_o nothing_o can_v better_v dispose_n towards_o maturation_n and_o suppuration_n than_o relax_v mollefy_a and_o resolve_v 4._o it_o exulcerate_v or_o cause_n blister_n or_o at_o least_o rubify_v tender_a skin_n if_o it_o be_v very_o strong_a because_o of_o its_o volatile_a salt_n as_o cantharides_n spearwort_n and_o other_o thing_n do_v upon_o the_o same_o account_n but_o this_o effect_n belong_v main_o to_o the_o true_a mastack_n or_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o drop_n from_o the_o incision_n make_v in_o the_o head_n of_o the_o poppy_n more_o especial_o the_o theban_a which_o afford_v a_o most_o powerful_a juice_n for_o exulcerate_v or_o blister_v be_v but_o a_o strong_a full_a and_o therefore_o painful_a resolution_n as_o you_o see_v by_o the_o cuticle_n upon_o blister_n resolve_v into_o a_o kind_n of_o jelly_n 5._o it_o be_v psilothrick_n for_o the_o same_o reason_n for_o while_o it_o so_o resolve_v the_o part_n it_o loosen_v the_o root_n of_o the_o hair_n and_o so_o cause_v its_o shed_n 6._o it_o hurt_v the_o eye_n because_o of_o its_o acrimony_n by_o reason_n of_o the_o volatile_a salt_n 7._o it_o cause_v itch_a in_o the_o skin_n by_o the_o titillation_n of_o the_o same_o volatile_a salt_n as_o you_o find_v by_o the_o application_n of_o squill_n and_o the_o like_a 8._o it_o excite_v venery_n by_o the_o same_o titillation_n on_o the_o veneral_a membrane_n chap._n xvii_o the_o explication_n of_o the_o effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v note_v that_o because_o opium_n have_v be_v general_o hitherto_o use_v either_o crude_a or_o with_o its_o rosin_n in_o it_o the_o effect_n of_o opium_n be_v according_o consider_v as_o common_a experience_n thereupon_o have_v give_v opportunity_n of_o observe_v they_o but_o as_o i_o proceed_v i_o shall_v show_v you_o where_o the_o resinous_n part_n of_o opium_n be_v concern_v in_o the_o effect_n 1._o it_o be_v manifest_a why_o opium_n may_v well_o