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former_a impediment_n be_v now_o at_o length_n free_a i_o come_v in_o the_o next_o place_n to_o establish_v the_o grand_a pillar_n upon_o which_o the_o whole_a weight_n of_o this_o my_o rude_a structure_n rely_v that_o be_v to_o make_v it_o appear_v to_o be_v not_o only_o possible_a but_o also_o probable_a that_o a_o few_o little_a drop_n of_o liquor_n instill_v into_o the_o fibre_n of_o the_o heart_n shall_v only_o by_o cause_v they_o to_o swell_v or_o by_o dilate_v their_o pore_n abbreviate_v they_o with_o a_o force_n great_a enough_o to_o make_v a_o constriction_n of_o the_o heart_n this_o if_o i_o shall_v be_v able_a to_o do_v i_o shall_v not_o despair_v of_o finish_v my_o building_n as_o i_o at_o first_o design_v for_o the_o remain_a part_n of_o my_o work_n will_v be_v little_a and_o easy_a as_o for_o the_o possibility_n of_o so_o great_a a_o effect_n from_o a_o cause_n that_o seem_v to_o be_v so_o weak_a and_o inconsiderable_a that_o may_v be_v without_o much_o difficulty_n prove_v from_o the_o just_a analogy_n or_o similitude_n of_o this_o effect_n to_o many_o other_o as_o great_a if_o not_o great_a effect_n common_o observe_v to_o arise_v from_o the_o like_a cause_n for_o mechanic_n example_n of_o this_o kind_n be_v every_o where_o so_o obvious_a to_o sense_n and_o so_o numerose_n that_o only_o to_o enumerate_v they_o will_v be_v a_o task_n hard_a and_o tediose_fw-la out_o of_o so_o vast_a a_o multitude_n therefore_o i_o will_v for_o brevitie_n sake_n select_a only_a two_o such_o as_o be_v not_o only_o pertinent_a and_o adequate_a to_o my_o subject_n but_o also_o in_o themselves_o eminent_o remarkable_a the_o first_o be_v of_o a_o new_a cable_n which_o upon_o wet_n will_v very_o much_o swell_v or_o become_v thick_a shrink_v and_o shorten_v itself_o beyond_o the_o belief_n of_o any_o but_o a_o mariner_n and_o galilaeus_fw-la have_v well_o observe_v this_o swell_a and_o
act_v continual_o but_o interrupt_o or_o per_fw-la vice_n short_a and_o almost_o isochronic_a or_o equal_a quiet_n interpose_v so_o that_o the_o blood_n express_v by_o the_o heart_n do_v not_o flow_v thence_o in_o a_o continue_a course_n as_o river_n and_o fountain_n do_v that_o be_v without_o intermission_n carry_v on_o by_o the_o weight_n of_o their_o water_n but_o gush_v forth_o and_o stop_v alternate_o though_o this_o vicissitude_n be_v exact_o regular_a and_o proceed_v in_o a_o constant_a order_n now_o these_o thing_n consider_v it_o may_v seem_v consentaneous_a to_o conclude_v that_o the_o motion_n of_o the_o blood_n can_v be_v continuus_fw-la since_o two_o pause_n or_o quiet_n be_v interpose_v betwixt_o every_o two_o pulsation_n or_o systole_n of_o the_o heart_n during_o each_o of_o which_o the_o motion_n cease_v but_o on_o the_o contrary_a aught_o to_o be_v esteem_v and_o call_v a_o interrupt_a and_o mix_v motion_n and_o yet_o notwithstanding_o the_o verisimilitude_n of_o this_o conclusion_n i_o doubt_v not_o to_o lay_v down_o and_o expose_v to_o your_o examination_n this_o first_o proposition_n that_o the_o blood_n be_v carry_v in_o a_o round_a through_o the_o body_n of_o a_o animal_n in_o a_o true_o continue_v and_o never_o interrupt_v motion_n this_o perhaps_o may_v sound_v like_o a_o paradox_n but_o that_o shall_v not_o a-whit_n discourage_v i_o from_o assert_v it_o while_o i_o remember_v that_o remarkable_a sentence_n of_o minutius_n felix_n in_o octavio_n inest_fw-la &_o in_fw-la incredibili_fw-la verum_fw-la &_o in_o verisimili_fw-la mendacium_fw-la though_o it_o be_v true_a and_o evident_a that_o the_o heart_n do_v not_o in_o the_o time_n of_o its_o pause_n express_v any_o blood_n into_o the_o artery_n yet_o it_o be_v not_o true_a that_o the_o blood_n contain_v in_o the_o artery_n in_o the_o viscera_n in_o the_o habit_n of_o the_o body_n and_o in_o the_o vein_n do_v at_o the_o same_o time_n stagnate_n and_o stop_v its_o course_n but_o on_o the_o contrary_n be_v always_o carry_v on_o in_o its_o journey_n though_o with_o unequal_a velocity_n first_o the_o verity_n of_o this_o appear_v in_o the_o artery_n for_o the_o afflux_n of_o blood_n from_o the_o heart_n be_v whole_o intercept_v either_o by_o a_o ligature_n apply_v to_o the_o aorta_fw-mi at_o its_o original_n or_o by_o cut_v out_o the_o heart_n itself_o as_o be_v common_o do_v in_o frog_n and_o viper_n we_o see_v that_o nevertheless_o the_o blood_n wherewith_o the_o artery_n be_v fill_v be_v by_o degree_n squeeze_v out_o so_o that_o they_o be_v soon_o after_o leave_v altogether_o empty_a and_o doubtless_o this_o exinanition_n of_o the_o artery_n happen_v because_o they_o by_o their_o own_o spontaneous_a motion_n constringe_v themselves_o and_o contract_v their_o circular_a fibre_n express_v the_o blood_n into_o the_o habit_n of_o the_o part_n and_o be_v at_o the_o same_o time_n compress_v also_o by_o the_o contraction_n and_o tension_n or_o the_o peristaltic_a motion_n of_o all_o the_o muscle_n of_o the_o body_n from_o the_o observation_n of_o this_o vulgar_a phaenomenon_n viz._n the_o emptiness_n of_o the_o artery_n in_o dead_a body_n the_o ancient_n perhaps_o take_v occasion_n to_o believe_v and_o teach_v that_o not_o blood_n but_o only_o vital_a spirit_n be_v contain_v in_o the_o artery_n second_o this_o appear_v also_o in_o the_o vein_n for_o that_o the_o blood_n do_v continual_o flow_v on_o in_o they_o likewise_o not_o only_a when_o it_o be_v urge_v forward_o by_o the_o arterial_a blood_n pursue_v it_o but_o even_o in_o the_o time_n of_o the_o heart_n pause_n be_v evince_v from_o this_o that_o then_o the_o blood_n run_v on_o through_o the_o trunk_n of_o the_o vena_fw-la cava_fw-la to_o replenish_v the_o right_a ventricle_n of_o the_o heart_n but_o why_o do_v i_o misspend_v time_n in_o allege_v reason_n to_o prove_v a_o truth_n that_o be_v manifest_a to_o sense_n in_o phlebotomy_n no_o soon_o be_v a_o vein_n open_v than_o the_o blood_n flow_v forth_o with_o a_o swift_a stream_n and_o while_o the_o wound_n be_v open_a continues_z to_o flow_v without_o pause_n or_o interruption_n which_o be_v a_o demonstration_n of_o the_o thing_n propose_v viz._n of_o the_o continual_a motion_n of_o the_o blood_n in_o the_o vein_n be_v thus_o assure_v of_o the_o effect_n let_v we_o proceed_v to_o investigate_v the_o cause_n which_o be_v not_o equal_o evident_a nor_o can_v we_o hope_v certain_o to_o solve_v this_o problem_n without_o inquire_v the_o mechanical_a reason_n of_o the_o continual_a motion_n of_o the_o blood_n through_o the_o vein_n this_o therefore_o i_o will_v now_o attempt_v to_o do_v that_o nature_n have_v institute_v no_o immediate_a communication_n betwixt_o the_o capillary_a artery_n and_o the_o capillary_a vein_n per_fw-la anastomôsin_fw-la be_v manifest_a to_o sense_n and_o now_o acknowledge_v by_o all_o learned_a anatomist_n and_o therefore_o it_o can_v stand_v with_o reason_n to_o imagine_v that_o the_o blood_n in_o its_o circular_a course_n be_v emit_v immediate_o out_o of_o the_o artery_n into_o the_o vein_n these_o vessel_n be_v separate_a and_o though_o we_o opine_n that_o there_o be_v some_o secret_a communication_n betwixt_o the_o extreme_a orifice_n of_o the_o artery_n and_o those_o of_o the_o capillary_a vein_n by_o the_o intermediate_v spongy_a substance_n of_o the_o flesh_n viscera_n and_o glandule_n or_o by_o the_o cribrose_n substance_n of_o the_o bone_n as_o by_o the_o pore_n of_o a_o pumice_n stone_n yet_o we_o be_v still_o to_o seek_v by_o what_o motive_n force_v the_o blood_n may_v be_v carry_v on_o from_o those_o intermediate_v porosity_n and_o insinuate_v into_o the_o vein_n first_o because_o it_o be_v consentaneous_a that_o the_o impulsive_a force_n whereby_o the_o systole_n of_o the_o heart_n squirt_n the_o blood_n into_o the_o artery_n be_v by_o degree_n weaken_v and_o at_o length_n languid_a in_o those_o straits_n of_o the_o extreme_a vessel_n and_o of_o the_o intermediate_v porosity_n second_o because_o the_o orifice_n of_o the_o capillary_a vein_n can_v continue_v always_o open_a and_o dilate_v their_o consistence_n be_v not_o hard_a and_o bony_a but_o membranose_n soft_a and_o slippery_a so_o that_o they_o be_v apt_a to_o be_v close_v by_o connive_v and_o consequent_o to_o hinder_v the_o ingress_n of_o the_o blood_n new_o arrive_v three_o because_o here_o we_o can_v have_v no_o recourse_n to_o the_o compression_n of_o the_o viscera_n and_o the_o muscle_n whereby_o the_o blood_n shall_v be_v squeeze_v into_o the_o orifice_n of_o the_o capillary_a vein_n for_o we_o see_v that_o the_o blood_n be_v suck_v up_o by_o the_o capillary_a vein_n not_o only_a when_o the_o muscle_n be_v invigorate_v and_o upon_o the_o stretch_n but_o also_o when_o they_o be_v quiet_a and_o relax_v and_o do_v not_o exercise_v their_o compressive_a power_n as_o be_v most_o evident_a in_o sleep_n when_o the_o circulation_n proceed_v without_o intermission_n this_o be_v confirm_v from_o hence_o that_o in_o the_o brain_n in_o the_o medullary_a substance_n of_o the_o bone_n where_o no_o compression_n can_v be_v admit_v the_o capillary_a vein_n receive_v the_o blood_n as_o free_o as_o in_o the_o soft_a flesh_n itself_o see_v then_o that_o the_o effect_n can_v be_v deny_v viz._n that_o all_o the_o blood_n effuse_v out_o of_o the_o artery_n be_v after_o absorb_v and_o carry_v off_o by_o the_o vein_n to_o be_v bring_v back_o again_o into_o the_o heart_n and_o see_v also_o that_o this_o be_v not_o effect_v by_o way_n of_o attraction_n there_o be_v no_o such_o thing_n as_o attraction_n in_o nature_n as_o i_o have_v more_o than_o once_o elsewhere_o prove_v we_o be_v compel_v to_o assert_v that_o the_o blood_n be_v imbibe_v by_o the_o capillary_a vein_n for_o the_o same_o reason_n and_o by_o the_o same_o mechanic_n action_n by_o which_o syphon_n sponge_n filtre_n chord_n and_o all_o porose_a body_n be_v penetrate_v by_o water_n with_o which_o they_o be_v moisten_v which_o power_n be_v no_o other_o than_o the_o gravity_n of_o the_o fluid_n itself_o which_o be_v augment_v by_o the_o impetus_fw-la of_o its_o proper_a motion_n and_o by_o the_o impulse_n communicate_v to_o it_o from_o external_a force_n so_o the_o motive_n force_n of_o gravity_n which_o the_o blood_n can_v want_v no_o more_o than_o water_n can_v when_o it_o find_v the_o small_a channel_n of_o the_o capillary_a vein_n open_a for_o they_o can_v never_o be_v so_o close_o constringe_v by_o the_o flag_a and_o connivency_n of_o their_o thin_a membrane_n as_o to_o leave_v no_o entrance_n for_o a_o fluid_a as_o appear_v in_o the_o pore_n of_o rope_n how_o hard_o soever_o twist_v must_v of_o necessity_n overcome_v the_o weak_a resistance_n of_o the_o straits_n in_o all_o filtre_n and_o porose_a body_n and_o consequent_o the_o blood_n may_v be_v insinuate_v into_o the_o capillary_a vein_n by_o a_o mechanic_n action_n like_o that_o of_o filtration_n if_o this_o proposition_n
nay_o that_o he_o understand_v no_o more_o the_o mechanic_n reason_n of_o their_o conformation_n than_o if_o he_o have_v never_o hear_v of_o or_o see_v they_o nor_o in_o truth_n do_v father_n paul_n who_o yet_o i_o never_o can_v mention_v without_o secret_a veneration_n if_o the_o afore-recited_n account_n and_o what_o follow_v immediate_o after_o give_v by_o his_o most_o intimate_a friend_n during_o his_o life_n and_o after_o his_o historian_n fulgentio_n be_v true_a and_o full_a for_o in_o fulgentio_n narration_n of_o the_o manner_n how_o the_o father_n come_v first_o to_o find_v out_o the_o valve_n there_o be_v this_o passage_n and_o upon_o his_o own_o natural_a judgement_n he_o set_v himself_o to_o cut_v with_o more_o exquisite_a observation_n whereupon_o he_o find_v out_o those_o valvulae_fw-la and_o the_o right_a use_n of_o they_o which_o do_v not_o only_o stop_v and_o hinder_v the_o blood_n from_o dilate_v itself_o by_o its_o weight_n into_o the_o vein_n as_o we_o observe_v in_o some_o crooked_a and_o swell_v knot_n but_o also_o that_o blood_n run_v up_o and_o down_o with_o so_o much_o liberty_n and_o in_o so_o great_a quantity_n it_o may_v easy_o suffocate_v the_o natural_a heat_n of_o those_o part_n which_o ought_v to_o receive_v their_o nourishment_n from_o it_o whence_o it_o be_v plain_o apparent_a that_o the_o father_n also_o attribute_v a_o double_a use_n to_o the_o valve_n one_o the_o very_a same_o with_o the_o former_a dream_v of_o by_o aquapendens_fw-la who_o probable_o borrow_v it_o of_o the_o father_n viz._n to_o prevent_v the_o dilatation_n of_o the_o blood_n into_o varices_fw-la by_o stop_v its_o impetuous_a motion_n up_o and_o down_o in_o the_o vein_n the_o other_o quite_o contrary_a to_o aquapendens_n second_o use_n viz._n to_o prevent_v a_o surfeit_n of_o the_o part_n upon_o too_o much_o blood_n and_o a_o extinction_n or_o suffocation_n of_o their_o natural_a heat_n by_o that_o excess_n whereas_o aquapendens_fw-la fear_v they_o will_v be_v famish_a if_o the_o valve_n do_v not_o detain_v their_o food_n as_o tantalus_n be_v feign_v to_o be_v now_o if_o these_o be_v true_o the_o father_n sentiment_n concern_v the_o valve_n certain_o he_o have_v no_o right_a conception_n of_o nature_n design_n in_o make_v they_o as_o may_v be_v collect_v from_o the_o precedent_a demonstration_n of_o their_o true_a use_n to_o come_v then_o to_o a_o conclusion_n and_o draw_v all_o the_o line_n of_o this_o scrutiny_n to_o a_o point_n since_o it_o be_v evident_a that_o neither_o father_n paul_n himself_o nor_o his_o disciple_n aquapendens_fw-la have_v a_o right_a notion_n of_o the_o proper_a use_n of_o the_o valve_n and_o that_o both_o believe_v the_o blood_n to_o flow_v out_o of_o the_o great_a vein_n into_o the_o less_o which_o the_o fabric_n and_o situation_n of_o the_o valve_n plain_o contradict_v it_o necessary_o follow_v that_o neither_o of_o they_o can_v be_v author_n of_o that_o much_o more_o noble_a and_o more_o difficult_a invention_n of_o the_o circulation_n or_o the_o blood_n which_o it_o be_v moral_o impossible_a for_o any_o man_n to_o deduce_v from_o their_o absurd_a opinion_n concern_v the_o use_n of_o the_o valve_n and_o the_o glory_n of_o which_o be_v whole_o due_a to_o that_o incomparable_a man_n dr._n harvy_n who_o by_o admirable_a sagacity_n of_o spirit_n by_o numerose_n experiment_n and_o observation_n anatomical_a and_o by_o assiduous_a meditation_n perhaps_o also_o by_o the_o secret_a manuduction_n of_o fate_n that_o have_v reserve_v the_o secret_a for_o his_o knowledge_n attain_v at_o length_n to_o the_o invidiose_fw-la felicity_n of_o find_v it_o out_o and_o reveal_v it_o to_o the_o world_n i_o wonder_v therefore_o that_o some_o man_n of_o not_o obscure_a name_n in_o the_o catalogue_n of_o anatomist_n have_v show_v themselves_o so_o ungrateful_a and_o envious_a towards_o this_o immortal_a man_n as_o to_o ascribe_v this_o divine_a invention_n to_o padre_n paolo_n i_o mean_v sanguinis_fw-la joh._n walaeus_n and_o tho._n bartholinus_n the_o former_a of_o who_o doubt_v not_o to_o write_v thus_o vir_fw-la incomparabilis_fw-la paulus_n servita_n venetus_n valvularum_fw-la in_o venis_fw-la fabricam_fw-la observavit_fw-la accuratiùs_fw-la quam_fw-la magnus_fw-la anatomicus_n fabricius_n ab_fw-la aquapendente_fw-la postea_fw-la edidit_fw-la &_o ex_fw-la ea_fw-la valvularum_fw-la constitutione_n aliisque_fw-la experimentis_fw-la hunc_fw-la sanguinis_fw-la motum_fw-la puta_fw-la circularem_fw-la deduxit_fw-la egregioque_fw-la scripto_fw-la asseruit_fw-la quod_fw-la etiamnum_fw-la intelligo_fw-la apud_fw-la venetos_n asservari_fw-la ab_fw-la hoc_fw-la servita_n edoctus_fw-la vir_fw-la doctissimus_fw-la gulielmus_fw-la harveius_fw-la sanguinis_fw-la hunc_fw-la motum_fw-la accuratiùs_fw-la indagavit_fw-la inventis_fw-la auxit_fw-la probavit_fw-la firmiùs_fw-la &_o svo_fw-la divulgavit_fw-la nomine_fw-la the_o other_o have_v the_o confidence_n to_o affirm_v 26._o that_o veslingius_n have_v communicate_v to_o he_o as_o a_o secret_a never_o to_o be_v reveal_v forsooth_o to_o any_o three_o person_n that_o the_o circulation_n of_o the_o blood_n be_v the_o invention_n of_o father_n paul_n the_o servite_fw-la who_o have_v write_v a_o book_n of_o it_o which_o be_v in_o the_o custody_n of_o fulgentio_n at_o venice_n to_o refute_v this_o palpable_a fiction_n to_o what_o i_o have_v already_o say_v of_o father_n paul_n ignorance_n of_o the_o right_a use_n of_o the_o valve_n i_o need_v add_v only_o this_o that_o if_o fulgentio_n have_v have_v in_o his_o hand_n any_o such_o manuscript_n of_o the_o father_n as_o these_o detractor_n have_v imagine_v it_o be_v wonderful_a strange_a he_o shall_v never_o so_o much_o as_o mention_v either_o that_o or_o the_o circulation_n in_o his_o whole_a history_n of_o the_o father_n life_n when_o of_o all_o the_o subtle_a speculation_n and_o discovery_n of_o natural_a secret_n by_o he_o attribute_v to_o the_o father_n nothing_o will_v have_v so_o much_o conduce_v to_o the_o propagation_n of_o his_o glory_n as_o that_o here_o therefore_o i_o put_v a_o end_n to_o this_o long_a digression_n to_o which_o the_o necessary_a contemplation_n of_o the_o valve_n give_v a_o invite_a occasion_n and_o which_o be_v intend_v only_o to_o do_v right_a to_o the_o venerable_a memory_n of_o dr._n harvy_n all_o lover_n of_o truth_n as_o well_o as_o all_o member_n of_o this_o noble_a society_n will_v i_o presume_v easy_o pardon_v ¶_o ⸫_o have_v inquire_v into_o the_o velocity_n of_o the_o motion_n of_o the_o blood_n in_o the_o vein_n and_o the_o mechanic_n cause_v thereof_o let_v we_o next_o consider_v the_o velocity_n of_o the_o motion_n of_o the_o same_o blood_n in_o the_o artery_n for_o the_o clear_a understanding_n of_o which_o i_o lay_v down_o this_o three_o proposition_n proposition_n iii_o that_o the_o artery_n of_o a_o animal_n their_o constriction_n or_o pulsation_n be_v complete_a do_v not_o remain_v whole_o empty_a of_o blood_n evident_a it_o be_v even_o to_o sense_n that_o all_o the_o vein_n of_o a_o sanguineous_a animal_n take_v together_o be_v large_a or_o more_o capacious_a perhaps_o in_o a_o quadruple_a proportion_n than_o all_o the_o artery_n put_v together_o and_o the_o whole_a mass_n of_o blood_n run_v through_o all_o both_o vein_n and_o artery_n which_o mass_n in_o fullgrown_a man_n common_o exceed_v not_o 18_o or_o 20_o pint_n and_o though_o the_o vein_n by_o reason_n of_o their_o transparent_a coat_n always_o appear_v full_a of_o blood_n yet_o a_o man_n may_v doubt_v whether_o the_o artery_n also_o be_v always_o full_a that_o be_v whether_o they_o only_o give_v passage_n to_o the_o blood_n in_o the_o time_n of_o the_o pulsation_n and_o then_o in_o the_o time_n of_o their_o quiet_n remain_v whole_o empty_a or_o not_o to_o resolve_v this_o doubt_n therefore_o i_o say_v that_o the_o artery_n if_o they_o be_v whole_o empty_a in_o the_o interval_n of_o their_o pulsation_n then_o be_v lay_v naked_a to_o the_o sight_n they_o will_v appear_v constringe_v and_o lank_a like_a chord_n extend_v but_o our_o eye_n assure_v we_o that_o on_o the_o contrary_n they_o retain_v their_o round_a and_o plump_a figure_n and_o be_v press_v by_o the_o finger_n resist_v the_o pressure_n neither_o of_o which_o can_v possible_o consist_v with_o a_o total_a exinanition_n again_o the_o vein_n be_v lay_v naked_a if_o after_o the_o pulsation_n of_o the_o heart_n the_o artery_n remain_v empty_a then_o certain_o will_v the_o pipe_n of_o the_o vein_n by_o the_o quantity_n of_o 5_o pint_n of_o blood_n crowd_v into_o they_o more_o than_o what_o they_o be_v proportion_v to_o contain_v be_v distend_v at_o least_o a_o three_o part_n more_o than_o they_o ought_v but_o this_o be_v sensible_o false_a for_o their_o coat_n be_v not_o distend_v beyond_o their_o usual_a rate_n ergo_fw-la the_o artery_n be_v at_o no_o time_n whole_o empty_a moreover_o in_o animal_n who_o artery_n be_v transparent_a as_o in_o snake_n viper_n eel_n frog_n etc._n etc._n we_o may_v from_o their_o purple_a or_o bluish_a colour_n perceive_v the_o artery_n to_o be_v full_a of_o
perfection_n and_o that_o the_o sacrifice_n of_o praise_n offer_v up_o to_o heaven_n from_o the_o mouth_n of_o one_o who_o have_v well_o study_v what_o he_o commend_v be_v more_o suitable_a to_o the_o divine_a nature_n than_o the_o blind_a applause_n of_o the_o ignorant_a wherefore_o since_o we_o be_v now_o come_v to_o the_o efficient_a cause_n of_o the_o before_o describe_v motion_n of_o the_o blood_n which_o our_o sense_n plain_o show_v and_o all_o learned_a anatomist_n acknowledge_v to_o be_v the_o pulsation_n of_o the_o heart_n and_o since_o it_o be_v equal_o manifest_a that_o this_o pulsation_n be_v a_o action_n entire_o mechanic_n let_v we_o attentive_o contemplate_v and_o consider_v the_o mechanism_n of_o the_o heart_n from_o whence_o that_o action_n necessary_o proceed_v for_o the_o true_a reason_n and_o manner_n of_o the_o pulsation_n be_v know_v our_o disquisition_n of_o the_o motion_n of_o the_o blood_n will_v be_v complete_a and_o we_o shall_v so_o much_o the_o more_o admire_v and_o laud_v the_o skill_n of_o the_o divine_a engineer_n who_o contrive_v and_o make_v the_o machine_n of_o the_o heart_n of_o so_o small_a a_o bulk_n and_o yet_o of_o so_o stupendous_a power_n and_o force_n nor_o ought_v we_o to_o despair_v of_o find_v what_o we_o search_v for_o because_o though_o the_o heart_n of_o man_n be_v to_o we_o inscrutable_a as_o to_o its_o 〈◊〉_d thought_n and_o reserve_v it_o seem_v not_o to_o be_v inscrutable_a as_o to_o its_o fabric_n and_o conformation_n i_o will_v therefore_o endeavour_v to_o explain_v the_o structure_n of_o it_o that_o the_o heart_n be_v a_o muscle_n of_o the_o same_o nature_n with_o the_o muscle_n of_o the_o limb_n be_v apparent_a to_o the_o sight_n and_o will_v be_v more_o apparent_a if_o the_o carnose_n fibres_fw-fr of_o it_o be_v plump_v up_o by_o boil_v for_o than_o we_o may_v plain_o perceive_v that_o it_o be_v compose_v of_o robu_v fleshy_a fibre_n of_o the_o same_o prismatical_a figure_n of_o the_o same_o colour_n and_o consistence_n and_o tenacity_n as_o the_o fibre_n of_o other_o muscle_n have_v and_o therefore_o the_o fibre_n of_o it_o be_v in_o like_a manner_n inelongable_a and_o resist_v distraction_n they_o as_o those_o of_o other_o muscle_n spontaneous_o contract_v themselves_o after_o extension_n may_v be_v swell_v and_o acquire_v hardness_n when_o they_o act_v in_o the_o pulsation_n of_o the_o heart_n so_o far_o the_o resemblance_n hold_v but_o yet_o the_o fibrose_a constitution_n of_o the_o heart_n differ_v from_o that_o of_o all_o other_o muscle_n in_o this_o that_o the_o flesh_n of_o the_o heart_n be_v firm_a hard_a uniform_a of_o a_o deep_a ruddy_a colour_n nor_o be_v the_o prismatic_a column_n separate_v from_o the_o little_a membrane_n and_o innumerable_a tendinose_n fibres_n as_o the_o fibre_n of_o the_o other_o muscle_n be_v beside_o the_o disposition_n and_o configuration_n of_o the_o fibre_n of_o the_o heart_n be_v extreme_o divers_a from_o that_o observe_v in_o all_o other_o for_o here_o the_o fibre_n be_v neither_o direct_a nor_o parallel_v among_o themselves_o but_o curve_v and_o spiral_n and_o in_o wonderful_a manner_n various_o interweave_v and_o implicate_v not_o by_o a_o texture_n like_o that_o by_o which_o wicker_n basket_n be_v make_v as_o vesalius_n imagine_v they_o to_o be_v but_o dispose_v with_o a_o more_o admirable_a artifice_n for_o immediate_o under_o the_o outward_a membrane_n invest_v the_o heart_n from_o the_o basis_n of_o the_o heart_n and_o from_o the_o circular_a tendinose_n orifice_n of_o it_o in_o which_o the_o vena_fw-la cava_fw-la and_o the_o vena_fw-la arteriosa_fw-la be_v terminate_v as_o also_o from_o the_o beginning_n of_o the_o aorta_fw-mi and_o arteria_fw-la venosa_fw-la be_v propagate_v a_o stratum_fw-la or_o layer_n of_o carnose_n fibres_n which_o be_v almost_o aequidistant_a among_o themselves_o and_o tend_v direct_o from_o the_o basis_n towards_o the_o cone_n of_o the_o heart_n where_o various_o inflect_v and_o contex_v they_o be_v reflect_v towards_o the_o cavity_n or_o ventricles_n within_o the_o â—â—_o volution_n and_o mutual_a intersection_n seem_v to_o give_v to_o the_o heart_n its_o circular_a and_o conical_a figure_n in_o which_o it_o be_v not_o resemble_v by_o any_o other_o muscle_n whatsoever_o be_v disseminated_a in_o great_a multitude_n sprig_n of_o nerve_n derive_v from_o the_o interior_a branch_n of_o the_o eight_o pair_n proper_o name_v par_fw-fr vagum_fw-la all_o which_o pass_v betwixt_o the_o arteria_fw-la pulmonaris_fw-la and_o the_o aorta_fw-mi first_o bestow_v many_o small_a surcle_n upon_o the_o auriculae_fw-la on_o each_o side_n and_o then_o implant_v themselves_o into_o the_o fibrose_a substance_n of_o the_o heart_n in_o divers_a place_n the_o manner_n of_o which_o their_o implantation_n be_v plain_o visible_a in_o the_o heart_n of_o a_o calf_n lamb_n or_o other_o new_a bear_v animal_n while_o it_o be_v yet_o warm_a but_o because_o in_o thing_n anatomic_a the_o eye_n be_v a_o better_a instructor_n than_o the_o ear_n i_o have_v cause_v to_o be_v accurate_o represent_v in_o this_o figure_n the_o whole_a system_n of_o nerve_n pertain_v to_o the_o heart_n and_o its_o ear_n to_o help_v both_o the_o understanding_n and_o memory_n of_o young_a student_n for_o who_o sake_n chief_o lecture_n be_v at_o first_o institute_v in_o this_o college_n figure_n iii_o in_o this_o figure_n aa_n aa_o represent_v the_o nerve_n of_o the_o eight_o pair_n cut_v off_o which_o though_o derive_v from_o the_o same_o origine_fw-la be_v yet_o in_o a_o man_n after_o they_o have_v pass_v out_o of_o the_o skull_n divide_v into_o two_o trunk_n of_o which_o the_o exterior_a denote_v by_o bb_n be_v call_v the_o intercostal_a branch_n because_o in_o its_o descent_n towards_o the_o part_n of_o the_o low_a belly_n it_o receive_v many_o spriggs_n of_o other_o nerve_n shoot_v forth_o between_o the_o rib_n from_o the_o spinal_a marrow_n as_o auxiliaries_n and_o the_o interior_a name_v par_fw-fr vagum_fw-la from_o its_o various_a wind_n and_o turn_n first_o distribute_v divers_a surcle_n in_o its_o passage_n downward_o to_o the_o heart_n then_o subdivide_v itself_o into_o more_o thread_n be_v disseminated_a into_o the_o viscera_n contain_v in_o the_o abdomen_fw-la dd_o the_o plexus_fw-la of_o the_o former_a or_o intercostal_a branch_n call_v ramus_fw-la cervicalis_fw-la because_o in_o man_n it_o be_v site_v on_o each_o side_n in_o the_o middle_n of_o the_o neck_n i_fw-mi the_o plexus_fw-la of_o the_o nerve_n of_o the_o late_a branch_n or_o par_fw-fr vagum_fw-la f_o the_o cardiac_n plexus_fw-la in_o which_o be_v terminate_v small_a nervose_n tendrel_n ggg_n arise_v on_o each_o side_n from_o the_o plexus_fw-la cervicalis_fw-la of_o the_o intercostal_a nerve_n hh_o surcle_n of_o a_o conspicuous_a nerve_n shoot_v forth_o from_o the_o plexus_fw-la of_o the_o par_fw-fr vagum_fw-la and_o terminate_a itself_o in_o the_o plexus_fw-la cardiacus_fw-la two_o many_o nervose_a production_n from_o the_o plexus_fw-la of_o the_o par_fw-fr vagum_fw-la distribute_v to_o the_o pericardium_n to_o the_o vessel_n conjoin_v to_o the_o heart_n and_o to_o the_o ear_n of_o it_o k_o remarkable_a surcle_n of_o nerve_n from_o the_o plexus_fw-la cardiacus_fw-la which_o pass_v betwixt_o the_o arteria_fw-la pulmonaria_fw-la m_o and_o the_o aorta_fw-mi n_o be_v terminate_v in_o the_o substance_n of_o the_o heart_n ll_o two_o considerable_a nerve_n send_v from_o the_o par_fw-fr vagum_fw-la to_o the_o heart_n which_o be_v various_o combine_v as_o it_o be_v by_o mutual_a inosculation_n both_o among_o themselves_o and_o with_o nervose_a branch_n issue_v from_o the_o plexus_fw-la cardiacus_fw-la to_o the_o end_n doubtless_o that_o both_o may_v be_v strengthen_v by_o that_o union_n these_o seem_v to_o be_v the_o principal_a of_o all_o nerve_n pertain_v to_o the_o heart_n and_o most_o likely_a to_o convey_v influence_n from_o the_o brain_n to_o the_o heart_n whatever_o that_o influence_n be_v to_o invigorate_v it_o and_o maintain_v it_o in_o perpetual_a motion_n probable_o by_o supply_v the_o heart_n with_o succus_fw-la nutritius_fw-la in_o great_a plenty_n oooo_o the_o musculose_a substance_n of_o the_o heart_n into_o which_o the_o say_a nerve_n be_v insert_v in_o this_o manner_n have_v nature_n furnish_v the_o heart_n of_o man_n with_o store_n of_o nerve_n thereby_o provide_v for_o its_o strength_n and_o continual_a motion_n nor_o have_v she_o much_o diversify_v her_o work_n in_o the_o heart_n of_o brute_n for_o all_o the_o difference_n that_o hitherto_o have_v be_v observe_v in_o they_o as_o to_o the_o nerve_n be_v only_o this_o that_o beside_o the_o production_n that_o come_v from_o the_o nerve_n of_o the_o eight_o pair_n in_o a_o place_n somewhat_o high_o and_o be_v distribute_v to_o the_o heart_n in_o most_o brute_n animal_n there_o be_v moreover_o very_a many_o sprig_n shoot_v from_o the_o same_o nerve_n where_o they_o pass_v above_o the_o heart_n and_o receive_v as_o auxiliary_a supply_n nervose_a surcle_n pass_v betwixt_o the_o rib_n from_o the_o spinal_a
little_a canales_n within_o must_v therefore_o be_v full_a of_o small_a asperity_n it_o be_v necessary_a that_o the_o succus_fw-la nervosus_fw-la who_o consistence_n be_v not_o much_o thin_a than_o the_o white_a of_o a_o egg_n well_o beat_v shall_v pass_v through_o they_o with_o a_o slow_a and_o interrupt_a course_n and_o at_o length_n fall_v out_o of_o their_o low_a end_n in_o drop_n with_o equal_a pause_n between_o the_o drop_n where_o we_o find_v a_o parility_n of_o cause_n we_o may_v right_o expect_v a_o similitude_n of_o effect_n here_o i_o see_v two_o formidable_a difficulty_n stand_v like_o romantic_a giant_n in_o my_o way_n to_o deter_v i_o from_o proceed_v and_o i_o can_v without_o shame_n and_o infamy_n decline_v to_o encounter_v they_o one_o be_v that_o after_o the_o cardiac_n nerve_n be_v cut_v off_o and_o the_o heart_n itself_o take_v out_o of_o the_o body_n the_o pulsation_n of_o it_o continue_v for_o some_o time_n to_o remove_v this_o therefore_o i_o say_v that_o the_o cavity_n of_o the_o nerve_n annex_v to_o the_o heart_n may_v remain_v still_o full_a of_o and_o turgid_a with_o the_o roscid_n succus_fw-la nervosus_fw-la which_o be_v hinder_v from_o regress_n by_o their_o spontaneous_a contraction_n towards_o the_o heart_n and_o keep_v in_o a_o state_n of_o fluxility_n by_o the_o yet_o last_a warmth_n of_o the_o heart_n may_v for_o some_o time_n be_v instill_v into_o the_o fibre_n of_o it_o and_o by_o swell_v of_o they_o cause_n they_o to_o constringe_v the_o ventricles_n as_o before_o then_o the_o heart_n be_v irritate_v by_o the_o prick_n of_o a_o needle_n or_o some_o sharp_a and_o pungent_a liquor_n may_v be_v able_a by_o its_o peristaltic_a constriction_n to_o squeeze_v out_o the_o few_o remain_a drop_n of_o the_o roscid_a liquor_n which_o be_v do_v the_o pulsation_n cease_v for_o ever_o to_o the_o blood_n this_o effect_n ought_v not_o to_o be_v ascribe_v for_o after_o all_o relic_n of_o it_o have_v be_v with_o warm_a water_n and_o a_o syringe_n wash_v out_o of_o the_o ventricles_n and_o squeeze_v out_o of_o the_o vessel_n the_o pulsation_n notwithstanding_o will_v continue_v for_o sometime_o nor_o can_v it_o be_v with_o more_o reason_n ascribe_v to_o convulsion_n of_o the_o heart_n because_o all_o convulsion_n be_v disorderly_a and_o unequal_a both_o in_o the_o time_n of_o their_o gird_n and_o in_o those_o of_o their_o intermission_n whereas_o in_o this_o case_n the_o pulsation_n be_v regular_a and_o isochronical_a with_o equal_a pause_n nor_o to_o the_o heat_v communicate_v by_o the_o blood_n to_o the_o heart_n before_o it_o be_v exsect_v and_o not_o yet_o quite_o extinct_a because_o that_o borrow_a heat_n soon_o vanish_v and_o no_o external_a heat_n will_v revive_v the_o languish_a pulsation_n after_o all_o the_o roscid_a juice_n have_v be_v express_v out_o of_o the_o end_n of_o the_o nerve_n leave_v in_o the_o heart_n nothing_o then_o remain_v to_o solve_v this_o phaenomenon_n but_o the_o instillation_n of_o a_o few_o drop_n of_o our_o roscid_a liquor_n into_o the_o fibre_n of_o the_o heart_n to_o swell_v they_o and_o so_o urge_v they_o to_o constriction_n of_o the_o ventricles_n the_o other_o difficulty_n be_v this_o why_o be_v there_o not_o a_o pulsation_n after_o the_o same_o manner_n also_o in_o all_o the_o muscle_n of_o the_o limb_n since_o their_o fibre_n be_v of_o the_o same_o nature_n in_o all_o thing_n their_o disposition_n and_o direction_n only_o except_v since_o the_o orifice_n of_o the_o nerve_n pertain_v to_o they_o be_v in_o the_o brain_n as_o open_a to_o admit_v and_o imbibe_n the_o succus_fw-la nervosus_fw-la there_o elaborate_a and_o provide_v for_o they_o and_o since_o the_o same_o nerve_n be_v equal_o spungy_a and_o permeable_a in_o their_o constitution_n and_o so_o apt_a to_o transfer_v that_o liquor_n as_o the_o orifice_n of_o the_o cardiac_n nerve_n be_v to_o receive_v or_o their_o canales_n to_o transfer_v it_o if_o the_o whole_a apparatus_n be_v the_o same_o on_o both_o part_n whence_o come_v it_o that_o the_o same_o effect_n be_v not_o produce_v in_o both_o at_o this_o goliath_n i_o have_v in_o my_o scrip_n three_o pebble_n to_o throw_v and_o though_o my_o arm_n be_v weak_a i_o will_v not_o despair_v of_o hit_v he_o in_o the_o forehead_n first_o therefore_o i_o say_v that_o it_o be_v not_o yet_o certain_o know_v to_o any_o mortal_a man_n by_o what_o mediate_a cause_n the_o muscle_n of_o the_o limb_n be_v move_v at_o the_o command_n of_o the_o will_n whether_o by_o simple_a contraction_n of_o the_o original_n of_o the_o nerve_n insert_v into_o they_o or_o by_o the_o immission_n of_o the_o succus_fw-la nervosus_fw-la more_o copiose_o and_o swift_o at_o the_o time_n of_o their_o be_v put_v into_o action_n though_o the_o mechanism_n of_o their_o fibre_n make_v it_o more_o probable_a that_o they_o be_v move_v by_o immission_n of_o some_o liquor_n from_o the_o brain_n by_o which_o the_o rhomboid_a mesh_n or_o pore_n of_o their_o fibre_n be_v all_o at_o the_o same_o time_n swell_v and_o dilate_v a_o contraction_n of_o the_o whole_a muscle_n must_v in_o the_o same_o moment_n be_v effect_v and_o therefore_o i_o prefer_v this_o opinion_n to_o the_o former_a and_o have_v follow_v it_o in_o many_o place_n of_o this_o rude_a discourse_n but_o yet_o this_o opinion_n have_v not_o lead_v i_o to_o a_o discovery_n of_o the_o cause_n of_o the_o difference_n this_o present_a difficulty_n compel_v i_o to_o hunt_v after_o shall_v i_o imagine_v valve_n affix_v by_o nature_n to_o the_o orifice_n of_o the_o nerve_n of_o the_o muscle_n as_o mons_fw-la des_n cartes_n do_v in_o the_o body_n of_o they_o though_o such_o a_o artifice_n be_v not_o impossible_a yet_o beside_o that_o no_o such_o valve_n have_v hitherto_o be_v find_v in_o the_o brain_n i_o shall_v still_o be_v to_o seek_v for_o a_o cause_n to_o open_v and_o shut_v they_o ad_fw-la arbitrium_fw-la voluntatis_fw-la and_o so_o shall_v be_v put_v to_o a_o stand_n in_o my_o disquisition_n which_o to_o avoid_v some_o other_o organical_a contrivement_n such_o as_o may_v be_v not_o only_o possible_a but_o probable_a also_o and_o facile_a and_o fit_a to_o untie_v this_o gordian_a knot_n must_v be_v excogitated_a let_v it_o then_o be_v suppose_v that_o in_o the_o brain_n the_o orifice_n of_o the_o nerve_n thence_o elonge_v to_o the_o muscle_n of_o the_o limb_n and_o their_o canales_n be_v in_o such_o a_o peculiar_a manner_n form_v as_o at_o no_o time_n to_o take_v in_o and_o convey_v into_o the_o muscle_n more_o of_o the_o roscid_a liquor_n than_o what_o be_v sufficient_a to_o nourish_v they_o and_o recruit_v their_o vigour_n unless_o when_o at_o the_o command_n of_o the_o will_n under_o who_o jurisdiction_n they_o proper_o be_v the_o nerve_n be_v twitch_v up_o or_o convel_v at_o their_o original_n both_o their_o orifice_n be_v dilate_v to_o receive_v and_o their_o canales_n render_v more_o pervious_a to_o transmit_v in_o a_o moment_n into_o the_o fibre_n of_o the_o muscle_n to_o be_v use_v a_o great_a portion_n of_o the_o same_o invigorate_n liquor_n viz._n so_o much_o as_o be_v requisite_a to_o swell_v they_o up_o by_o replenish_n their_o pore_n and_o force_v they_o to_o contraction_n which_o be_v the_o common_a action_n of_o all_o muscle_n on_o the_o other_o part_n let_v it_o be_v suppose_v that_o in_o the_o brain_n nature_n have_v frame_v the_o original_n of_o the_o cardiac_n nerve_n by_o a_o different_a artifice_n namely_o such_o as_o that_o not_o only_o their_o orifice_n may_v always_o be_v open_a to_o imbibe_n but_o also_o their_o canales_n so_o easy_o pervious_a to_o transmit_v the_o roscid_a liquor_n as_o that_o without_o any_o vellication_n without_o any_o convulsive_a motion_n the_o same_o liquor_n may_v mere_o by_o the_o plenitude_n of_o the_o canales_n themselves_o be_v effuse_v guttulatim_fw-la into_o the_o fibre_n of_o the_o heart_n to_o cause_v the_o alternate_a constriction_n or_o pulsation_n of_o it_o and_o it_o be_v the_o more_o lawful_a for_o i_o to_o suppose_v this_o difference_n of_o structure_n in_o nerve_n ordain_v for_o different_a use_n because_o it_o be_v above_o all_o doubt_n that_o the_o optic_a nerve_n have_v a_o peculiar_a fabric_n and_o contexture_n wherein_o they_o differ_v from_o the_o auditory_a and_o all_o other_o nerve_n inservient_fw-la to_o the_o rest_n of_o the_o external_a sense_n and_o that_o the_o organ_n of_o every_o sense_n have_v its_o nerve_n of_o a_o peculiar_a constitution_n accommodate_v to_o the_o nature_n of_o its_o proper_a object_n though_o those_o difference_n consist_v in_o such_o minute_n and_o subtle_a artifices_fw-la as_o have_v hitherto_o elude_v our_o most_o curiose_fw-la research_v though_o assist_v by_o the_o best_a sort_n of_o microscope_n why_o then_o may_v it_o not_o be_v think_v that_o nature_n have_v give_v to_o the_o cardiac_n nerve_n also_o a_o constitution_n divers_a from_o that_o of_o all_o
the_o muscle_n of_o the_o heart_n be_v compose_v of_o the_o same_o constituent_a part_n with_o all_o other_o muscle_n viz._n of_o bundle_n of_o carnose_n fibres_n of_o the_o same_o tendinose_n and_o contrahible_a substance_n of_o the_o same_o prismatic_a figure_n in_o the_o same_o manner_n dispose_v layer_n upon_o layer_n bind_v down_o by_o mutual_a contexture_n in_o the_o same_o manner_n intersperse_v with_o branch_n of_o nerve_n fasten_v to_o tendon_n and_o enliven_v by_o blood_n irrigate_a they_o out_o of_o the_o artery_n in_o a_o word_n there_o be_v no_o sensible_a difference_n or_o disparity_n the_o figure_n of_o the_o whole_a heart_n except_v which_o yet_o do_v not_o diversify_v the_o organic_n nature_n of_o it_o no_o more_o than_o the_o diversity_n of_o figure_n among_o other_o muscle_n do_v make_v they_o of_o a_o different_a nature_n then_o if_o we_o consider_v the_o action_n of_o both_o the_o heart_n and_o all_o other_o muscle_n we_o shall_v find_v that_o as_o well_o the_o fibre_n of_o the_o heart_n as_o those_o of_o all_o other_o muscle_n act_v by_o contraction_n of_o themselves_o if_o we_o descend_v to_o the_o immediate_a motive_n cause_n and_o the_o mechanic_n mode_n of_o their_o operate_n from_o what_o we_o have_v already_o say_v it_o be_v manifest_a that_o it_o be_v as_o impossible_a for_o the_o heart_n to_o be_v inflate_v and_o move_v by_o a_o incorporeal_a faculty_n or_o by_o spirit_n or_o by_o the_o blood_n alone_o however_o violent_o rush_v into_o it_o or_o by_o the_o same_o blood_n to_o what_o degree_n soever_o rarify_v in_o its_o ventricles_n or_o by_o a_o fermentation_n conflict_n and_o displosion_n of_o acid_n and_o saline_n juice_n meet_v together_o in_o the_o heart_n as_o it_o be_v for_o the_o muscle_n of_o the_o limb_n to_o be_v regular_o move_v by_o the_o same_o cause_n it_o remain_v therefore_o that_o as_o all_o other_o muscle_n be_v move_v by_o contraction_n of_o their_o fibre_n the_o pore_n of_o they_o be_v fill_v and_o distend_v so_o also_o it_o be_v most_o probable_a that_o the_o proxime_fw-la or_o immediate_a cause_n of_o the_o motion_n i_o mean_v only_o the_o constriction_n of_o the_o heart_n be_v the_o dilatation_n or_o distension_n of_o the_o pore_n of_o its_o fibre_n which_o cause_v their_o abbreviation_n or_o contraction_n i._n e._n the_o systole_n of_o the_o heart_n but_o what_o the_o mediate_v cause_o be_v by_o which_o the_o pore_n of_o the_o fibre_n be_v dilate_v to_o the_o abbreviation_n of_o the_o fibre_n themselves_o we_o shall_v after_o a_o few_o minute_n inquire_v in_o the_o mean_a time_n i_o will_v lay_v down_o this_o other_o proposition_n that_o the_o mediate_v cause_n of_o the_o heart_n motion_n seem_v to_o differ_v from_o that_o by_o which_o the_o muscle_n of_o the_o limb_n be_v incite_v to_o voluntary_a motion_n since_o it_o be_v a_o truth_n know_v to_o all_o man_n that_o we_o can_v move_v what_o muscle_n we_o please_v of_o any_o limb_n and_o continue_v their_o motion_n as_o long_o as_o we_o please_v and_o stop_v it_o when_o we_o please_v but_o the_o motion_n of_o the_o heart_n be_v not_o subject_a to_o the_o empire_n of_o our_o will_n but_z like_o that_o of_o a_o mill_n perpetual_a whether_o we_o sleep_v or_o wake_v and_o since_o even_o without_o our_o knowledge_n or_o perception_n the_o heart_n as_o agitate_a by_o a_o certain_a natural_a necessity_n make_v most_o vehement_a and_o almost_o momentany_a stroke_n or_o jerk_n alternate_o short_a and_o isochronical_a or_o equal_o temporaneous_a pause_n interpose_v betwixt_o they_o nor_o ever_o either_o much_o vary_v that_o constant_a rhythm_n of_o its_o pulse_n while_o we_o be_v in_o the_o state_n of_o health_n or_o intermit_v the_o same_o during_o life_n therefore_o certain_o there_o must_v be_v somewhat_o of_o difference_n between_o the_o mediate_a cause_n of_o the_o heart_n natural_a motion_n on_o one_o part_n and_o the_o mediate_a cause_n of_o the_o voluntary_a motion_n of_o all_o other_o muscle_n on_o the_o other_o beside_o in_o a_o egg_n from_o the_o first_o day_n incubation_n of_o the_o hen_n the_o punctum_fw-la saliens_fw-la and_o then_o the_o vesicula_fw-la pulsans_fw-la exhibit_v to_o our_o sight_n this_o dance_n of_o life_n already_o begin_v when_o we_o can_v conceive_v it_o to_o be_v possible_a that_o there_o shall_v be_v in_o that_o first_o rudiment_n of_o the_o foetus_fw-la any_o sensation_n of_o good_a or_o evil_n any_o will_n to_o pursue_v the_o good_a or_o avoid_v the_o evil_a and_o when_o nothing_o of_o the_o brain_n be_v yet_o form_v nay_o more_o in_o the_o heart_n of_o a_o viper_n take_v out_o of_o the_o body_n and_o put_v into_o warm_a water_n the_o pulsation_n be_v observe_v to_o continue_v many_o hour_n when_o by_o reason_n of_o the_o abscission_n of_o the_o nerve_n all_o commerce_n betwixt_o the_o brain_n and_o the_o heart_n be_v extinct_a no_o sensation_n or_o election_n can_v be_v imagine_v to_o ordain_v and_o command_v that_o motion_n wherefore_o we_o be_v oblige_v to_o confess_v that_o the_o first_o and_o mediate_a cause_n of_o the_o heart_n pulsation_n be_v in_o some_o respect_n or_o other_o divers_a from_o that_o whereby_o the_o other_o muscle_n be_v incite_v to_o motion_n at_o the_o command_n of_o the_o will._n but_o to_o explore_v wherein_o this_o nice_a difference_n may_v most_o probable_o consist_v be_v a_o work_n of_o so_o great_a difficulty_n that_o i_o wish_v it_o be_v possible_a for_o i_o to_o revoke_v the_o temerarious_a promise_n i_o make_v to_o attempt_v it_o nor_o shall_v i_o have_v courage_n enough_o to_o carry_v i_o so_o much_o as_o one_o step_n far_o if_o i_o do_v not_o derive_v it_o whole_o from_o the_o well_o know_a candour_n and_o benignity_n of_o my_o most_o learned_a auditor_n for_o the_o remain_a part_n of_o my_o way_n though_o short_a be_v yet_o dark_a and_o rocky_a with_o precipice_n on_o both_o side_n and_o all_o the_o light_n i_o can_v expect_v must_v be_v from_o a_o few_o spark_n strike_v out_o of_o my_o flinty_a subject_n by_o the_o force_n of_o conjecture_n if_o therefore_o i_o chance_v to_o stumble_v or_o err_v humanity_n will_v oblige_v you_o rather_o to_o put_v forth_o your_o hand_n to_o support_v or_o guide_v i_o than_o to_o deride_v my_o blindness_n in_o hope_n of_o this_o favour_n i_o will_v venture_v to_o proceed_v certain_a it_o be_v that_o the_o first_o and_o mediate_a cause_n of_o the_o motion_n of_o the_o heart_n as_o well_o as_o that_o of_o the_o motion_n of_o the_o other_o muscle_n whatsoever_o it_o shall_v at_o length_n be_v find_v to_o be_v be_v derive_v to_o it_o by_o the_o nerve_n from_o the_o brain_n for_o as_o if_o the_o nerve_n insert_v into_o any_o muscle_n be_v strict_o compress_v by_o a_o ligature_n or_o cut_v off_o the_o power_n of_o motion_n in_o that_o muscle_n be_v present_o intercept_v or_o total_o destroy_v as_o common_a experience_n witness_v so_o if_o the_o nerve_n of_o the_o eight_o conjugation_n be_v either_o strict_o compress_v by_o a_o ligature_n round_o about_o or_o cut_v off_o in_o the_o neck_n of_o any_o animal_n there_o sudden_o will_v ensue_v a_o visible_a change_n in_o the_o motion_n of_o his_o heart_n witness_v the_o memorable_a experiment_n make_v by_o dr._n lower_n and_o record_v in_o his_o excellent_a book_n the_o cord_n 2._o where_o he_o affirm_v that_o the_o heart_n which_o before_o reciprocate_v its_o motion_n moderate_o and_o rhythmical_o present_o after_o the_o ligature_n have_v be_v make_v upon_o the_o say_a nerve_n begin_v to_o palpitate_v and_o tremble_v and_o by_o degree_n grow_v more_o and_o more_o languid_a till_o the_o poor_a creature_n die_v which_o be_v within_o two_o day_n other_o experiment_n confirm_v the_o same_o thing_n i_o may_v allege_v if_o it_o be_v not_o universal_o acknowledge_v by_o anatomist_n that_o the_o motive_n force_n of_o the_o heart_n depend_v upon_o some_o influence_n from_o the_o brain_n and_o among_o these_o one_o of_o the_o most_o accurate_a affirm_v that_o nature_n make_v the_o cerebellum_fw-la as_o a_o storehouse_n of_o animal_n spirit_n chief_o for_o the_o use_n of_o the_o heart_n that_o the_o motion_n of_o it_o may_v be_v perpetual_o maintain_v say_v pro_fw-la motu_fw-la cordis_n praestando_fw-la tam_fw-la sedula_fw-la &_o sollicita_fw-la fuit_fw-la naetura_fw-la ut_fw-la 2._o praeter_fw-la nervorum_fw-la propagines_fw-la ubique_fw-la in_o illud_fw-la densè_fw-la distributas_fw-la pro_fw-la continuo_fw-la spirituum_fw-la animalium_fw-la influxu_fw-la cerebellum_fw-la insuper_fw-la quasi_fw-la perenne_fw-fr corum_fw-la promptuarium_fw-la ei_fw-la accommodaverit_fw-la a_o cujus_fw-la benigna_fw-la &_o constante_n influentia_fw-la adeò_fw-la dependet_fw-la ut_fw-la fi_fw-la spirituum_fw-la influxus_fw-la vel_fw-la minimus_fw-la temporis_fw-la momento_n impediatur_fw-la motus_fw-la ejus_fw-la illicò_fw-la deficiat_fw-la but_o why_o have_v i_o recourse_n to_o the_o authority_n of_o man_n when_o nature_n herself_o in_o her_o constant_a process_n of_o form_v the_o part_n of_o a_o embryon_n seem_v to_o