opoponacis_fw-la terebinthinae_fw-la seminis_fw-la dauci_fw-la Ê’_n vj._n ob_fw-la iij._n opobalsami_n ana_fw-la Ê’_n vj._n ob_fw-la iiij_o thlaspios_fw-la thuris_fw-la myrrhae_fw-la ana_fw-la Ê’_n vj._n succi_n hyppocistidis_fw-la polij_fw-la seâ—elios_n ana_fw-la Ê’_n v._o ob_fw-la ij_o cypheos_n casiae_fw-la stiracis_n Ê’_n v_o ob_n iiij_o petroselini_fw-la Ê’_n iiij_o ob_fw-la iij._n opij_fw-la Ê’_n iiij_o ob_fw-la ij_o nardi_n gallicae_fw-la anae_fw-la Ê’_n iâ—â—_n seminis_fw-la feniculi_fw-la nardi_n indicae_fw-la gentianae_fw-la mei_fw-la athamantici_fw-la rosarum_fw-la siccarum_fw-la cardamomi_fw-la folij_fw-la anisi_fw-la Ê’_n iij_o acori_fw-la hiperici_fw-la ana_fw-la Ê’_n ij_o gummi_fw-la acaciae_fw-la phu_o pontici_fw-la scinci_n Ê’_n ij_o ob_fw-la ij_o vini_n choi_fw-fr &_o mellis_fw-la attici_fw-la desoumati_fw-la ana_fw-la q._n s_o because_o many_o learned_a man_n of_o this_o age_n do_v best_a allow_v the_o description_n of_o mithridatium_n deliver_v by_o damocrates_n as_o more_o artificial_o do_v in_o which_o the_o rule_n of_o compound_v of_o medicine_n be_v more_o exact_o follow_v and_o be_v in_o truth_n easy_a to_o be_v make_v of_o the_o apothecary_n better_o digest_v in_o order_n not_o have_v so_o small_a division_n in_o the_o proportion_n as_o this_o attribute_v to_o andromachus_n and_o so_o may_v better_o be_v make_v of_o the_o apothecary_n in_o what_o quantity_n shall_v seem_v good_a to_o he_o therefore_o i_o do_v think_v it_o not_o amiss_o in_o this_o place_n to_o recite_v that_o description_n also_o of_o mithridatium_n of_o damocrates_n as_o the_o same_o be_v express_v in_o the_o second_o book_n of_o galen_n the_o antidote_n that_o such_o as_o shall_v think_v better_a to_o follow_v the_o same_o may_v by_o this_o pamphlet_n know_v the_o ingredience_n which_o be_v this_o rec._n mirrhae_fw-la croci_fw-la ana_fw-la Ê’_n x_o agarici_fw-la zinziberis_fw-la cinnamomi_fw-la thuris_fw-la spicae_fw-la nardi_n thlaspios_n seselis_fw-la stechados_fw-mi ana_fw-it Ê’_n viij_o opobalsami_n costi_fw-la junci_fw-la odorati_fw-la styracis_fw-la galbani_fw-la terebinthinae_fw-la piperis_fw-la longi_fw-la castorei_fw-la sucoi_fw-fr hypocistidis_fw-la opoponacis_fw-la folij_fw-la malabathri_fw-la recentis_fw-la cassiae_fw-la ligneae_fw-la ana_fw-la Ê’_n seven_o polij_fw-la scordij_fw-la seminis_fw-la dauci_fw-la bdellij_fw-la piperis_fw-la albi_fw-la cypheos_fw-la carpobalsami_fw-la nardi_n celticae_fw-la gummi_fw-la ana_fw-la Ê’_n iâ—_n boni_fw-la ponderis_fw-la petroselini_fw-la opij_fw-la cardamomi_fw-la gentianae_fw-la seminis_fw-la feniculi_fw-la dictamni_fw-la foliorum_fw-la rosarum_fw-la anisi_fw-la asari_fw-la acori_fw-la ana_fw-la Ê’_n iij_o phu_o sagapeni_fw-la succi_n glicirrizae_fw-la mei_fw-la athamantici_fw-la ana_fw-la Ê’_n ij_o â—_o acaciae_fw-la ventris_n scinci_fw-la sem._n hiperici_fw-la vini_n &_o mellis_fw-la q._n s_o pliny_n in_o his_o 22._o make_v mention_n of_o a_o kind_n of_o mithridatium_n make_v of_o two_o dry_a walnut_n two_o fig_n xx_o leaf_n of_o rhue_n one_o grain_n of_o salt_n aetius_n and_o other_o writer_n die_v recite_v the_o same_o and_o they_o great_o commend_v it_o against_o poison_n &_o other_o pestilential_a disease_n of_o the_o quality_n and_o temperament_n of_o mithridatium_n it_o be_v of_o all_o man_n of_o our_o age_n confess_v and_o take_v for_o a_o truth_n that_o medicine_n compound_v have_v their_o virtue_n and_o do_v their_o effect_n according_a to_o the_o nature_n of_o the_o simples_n whereof_o they_o be_v compound_v so_o it_o must_v needs_o follow_v that_o mithridatium_n compound_v of_o many_o simples_n have_v diverse_a &_o sundry_a property_n &_o those_o agreeable_a to_o the_o ingredience_n and_o whereas_o in_o mithridatium_n be_v simples_n differ_v in_o quality_n some_o have_a power_n to_o heat_n some_o other_o to_o cool_v yet_o the_o great_a number_n be_v in_o quality_n hot_a and_o dry_a and_o albeit_o these_o be_v contrary_a and_o repugnant_a do_v make_v alteration_n the_o one_o with_o the_o other_o notwithstanding_o it_o must_v needs_o follow_v that_o those_o reaction_n not_o be_v infinite_a at_o the_o last_o one_o form_n and_o quality_n must_v result_v in_o the_o compound_n agreeable_a to_o the_o nature_n of_o those_o simples_n which_o do_v bear_v and_o carry_v dominion_n now_o whereas_o in_o mithriâ—atium_n y_fw-fr e_o must_v simples_n have_v quality_n to_o heat_n and_o dry_v it_o follow_v that_o mithridatium_n have_v a_o hot_a and_o dry_a power_n and_o as_o compound_n must_v have_v a_o time_n of_o fermentation_n and_o ripen_v for_o the_o reaction_n of_o the_o simples_n be_v not_o perfect_v in_o a_o moment_n so_o the_o quality_n or_o form_n which_o do_v arise_v by_o the_o work_n of_o one_o simple_a with_o a_o other_o have_v not_o his_o perfection_n present_o after_o y_o e_o mixture_n but_o a_o certain_a space_n of_o time_n must_v be_v give_fw-ge before_o we_o can_v just_o expect_v the_o true_a action_n of_o the_o medicine_n compound_v as_o proceed_v from_o the_o form_n of_o the_o medicine_n which_o do_v resulte_v by_o fermentation_n of_o the_o work_n of_o the_o simples_n in_o y_o e_o compound_n so_o that_o before_o y_z e_z due_a time_n we_o may_v not_o look_v for_o the_o virtue_n answerable_a to_o the_o composition_n but_o that_o some_o one_o simple_a above_o the_o rest_n may_v show_v his_o quality_n that_o the_o compound_n medicine_n may_v do_v a_o effect_n answerable_a to_o that_o simple_a and_o not_o as_o proceed_n from_o the_o whole_a composition_n in_o which_o respect_n galen_n write_v that_o theriacle_n new_o make_v do_v great_o provoke_v sleep_n by_o reason_n that_o opium_n that_o be_v the_o juice_n of_o poppy_n prepare_v mingle_a in_o it_o be_v of_o great_a force_n than_o other_o simples_n before_o fermentation_n do_v exercise_v his_o quality_n more_o than_o the_o rest_n and_o after_o that_o his_o quality_n be_v by_o fermentation_n with_o other_o simples_n break_v he_o can_v not_o so_o strong_o do_v his_o operation_n so_o theriacle_n after_o the_o just_a time_n of_o fermentation_n do_v not_o so_o mighty_o provoke_v sleep_n as_o new_a theriacle_n do_v the_o same_o be_v observe_v in_o mithridatium_n and_o all_o other_o compound_n that_o immediate_o after_o mixture_n the_o quality_n of_o the_o simples_n be_v strong_a and_o show_v their_o power_n best_o but_o certain_a it_o be_v that_o after_o due_a time_n of_o work_v when_o the_o compound_n be_v full_o ripe_a no_o one_o simple_a do_v work_v in_o it_o according_a to_o his_o own_o nature_n but_o by_o the_o reaction_n one_o common_a nature_n do_v result_v which_o can_v be_v attribute_v to_o any_o one_o or_o more_o simples_n but_o may_v be_v true_o say_v a_o common_a nature_n arise_v out_o of_o all_o the_o ingredience_n and_o from_o that_o form_n the_o action_n of_o the_o compound_n do_v proceed_v which_o form_n be_v to_o we_o not_o certain_o know_v y_z e_z effect_n be_v best_a learn_v by_o experience_n wherefore_o it_o be_v very_o wise_o write_v of_o joannes_n de_fw-fr sancto_fw-la amando_fw-la in_o his_o exposition_n upon_o the_o antitodary_n of_o nicolaus_n that_o it_o be_v better_a always_o to_o use_v a_o medicine_n compound_v exercise_v than_o one_o late_o invent_v whereof_o we_o have_v no_o experience_n for_o although_o we_o may_v by_o discourse_n of_o reason_n gather_v that_o y_z e_z compound_n as_o mithridatium_n be_v hot_a and_o dry_a because_o y_z e_o simples_n whereof_o it_o be_v make_v be_v the_o most_o part_n hot_a and_o dry_a and_o then_o experience_n do_v confirm_v this_o conjecture_n yet_o other_o quality_n of_o mithridatium_n and_o of_o other_o compound_n be_v not_o so_o easy_o know_v by_o any_o discourse_n or_o method_n but_o chief_o learn_v by_o experience_n for_o the_o common_a form_n from_o whence_o many_o secret_a virtue_n do_v proceed_v be_v not_o know_v by_o any_o learning_n or_o method_n so_o it_o must_v needs_o follow_v that_o the_o action_n of_o y_fw-fr e_o same_o form_n be_v not_o learn_v by_o method_n or_o doctrine_n but_o chief_o by_o experience_n in_o which_o respect_n also_o we_o have_v reason_n to_o retain_v the_o description_n deliver_v by_o mithridates_n before_o any_o other_o for_o y_z t_z that_o noble_a king_n give_v better_a proof_n in_o himself_o of_o the_o virtue_n of_o the_o medicine_n than_o any_o other_o have_v of_o it_o by_o any_o other_o composition_n that_o mithridatium_n be_v not_o so_o hot_a as_o theriacle_n compound_v after_o andromachus_n description_n which_o be_v in_o these_o day_n most_o follow_v and_o that_o it_o may_v more_o safe_o be_v use_v some_o learned_a man_n of_o our_o time_n by_o reason_n go_v about_o to_o discourse_n and_o prove_v y_z t_z theriacle_n be_v not_o in_o quantity_n so_o hot_a as_o mithridatium_n &_o in_o that_o respect_n do_v infer_v that_o it_o may_v more_o safe_o be_v use_v which_o they_o do_v gather_v for_o that_o in_o theriacle_n a_o great_a quantity_n of_o opium_n that_o be_v the_o juice_n of_o poppy_n prepare_v be_v then_o in_o mithridatium_n who_o cool_a power_n do_v much_o abate_v the_o heat_a quality_n of_o other_o medicine_n this_o argument_n in_o these_o two_o medicine_n new_o make_v before_o fermentation_n be_v perfect_a may_v take_v place_n
in_o the_o confection_n of_o theriacle_n than_o it_o follow_v that_o when_o like_a quantity_n of_o both_o be_v take_v as_o for_o example_n Ê’_n j_o sure_o a_o great_a portion_n of_o every_o one_o simple_a be_v take_v in_o mithridatium_n and_o lesser_a in_o theriacle_n the_o lesser_a quantity_n must_v needs_o have_v lesser_a strength_n in_o remedy_v other_o poison_n save_o that_o to_o the_o which_o the_o base_a or_o ground_n do_v call_v they_o so_o it_o remain_v firm_a that_o galen_n write_v as_o observe_v in_o his_o time_n that_o theriacle_n be_v in_o deed_n better_o than_o mithridatium_n in_o bite_v of_o viper_n and_o like_a beast_n and_o that_o mithridatium_n excead_v other_a in_o remedy_v all_o other_o poison_v take_v into_o the_o body_n and_o inward_a disease_n wherefore_o in_o this_o our_o country_n where_o no_o such_o peril_n and_o danger_n be_v of_o viper_n mithridatium_n by_o good_a reason_n ought_v to_o be_v repute_v of_o great_a estimation_n than_o theriacle_n of_o the_o composition_n of_o mithridatium_n it_o shall_v not_o be_v amiss_o in_o this_o place_n to_o declare_v the_o composition_n of_o this_o medicine_n and_o it_o be_v to_o be_v note_v that_o where_o all_o writer_n do_v great_o commend_v it_o yet_o certain_a it_o be_v that_o they_o do_v not_o in_o one_o sort_n describe_v the_o make_n of_o the_o same_o but_o almost_o every_o authore_fw-la have_v a_o several_a description_n differ_v in_o the_o number_n of_o the_o simples_n and_o also_o in_o y_z e_z proportion_n and_o quantity_n in_o time_n past_o y_fw-fr e_o apothecary_n in_o make_v of_o mithridatium_n follow_v most_v the_o description_n of_o nicolaus_n praepositus_fw-la of_o auicenna_n and_o of_o nicolaus_n mirepsicus_n some_o of_o aetius_n some_o of_o paulus_n the_o former_a description_n contain_v above_o one_o hundred_o simples_n be_v long_o and_o laborious_a and_o require_v many_o supply_n for_o simples_n unknowen_a wherefore_o in_o these_o our_o late_a day_n in_o which_o learned_a man_n have_v examine_v every_o thing_n perfect_o the_o most_o part_n have_v commend_v one_o of_o y_fw-fr e_o three_o composition_n express_v by_o galen_n in_o 2._o de_fw-la antid_v of_o the_o which_o two_o be_v take_v as_o galen_n write_v out_o of_o the_o book_n of_o andromachus_n the_o first_o find_v without_o name_n be_v attribute_v to_o andromachus_n as_o compound_v by_o he_o of_o other_o suppose_v the_o very_a same_o which_o be_v find_v in_o the_o closert_n of_o king_n mithridates_n &_o after_o transcribe_v in_o the_o work_n of_o andromachus_n the_o second_o description_n be_v also_o recite_v out_o of_o andromachus_n book_n under_o the_o name_n of_o antipater_n and_o cleophante_n the_o thyrd_o be_v refer_v to_o damocrates_n it_o do_v not_o appear_v by_o any_o thing_n write_v by_o galen_n which_o of_o these_o three_o composition_n be_v best_a to_o be_v follow_v and_o so_o of_o y_fw-fr e_o learned_a man_n of_o our_o time_n some_o have_v use_v the_o one_o and_o some_o the_o other_o many_o do_v best_o like_v of_o the_o first_o description_n attribute_v to_o andromachus_n both_o for_o that_o andromachus_n by_o the_o opinion_n of_o galen_n and_o of_o all_o other_o ancient_a writer_n be_v adjudge_v very_o skilful_a in_o compound_v of_o medicine_n &_o therein_o do_v far_o excel_v all_o physician_n of_o his_o time_n and_o also_o because_o it_o may_v be_v just_o gather_v that_o that_o description_n be_v the_o very_a same_o which_o mithridates_n use_v for_o in_o y_z e_o andromachus_n be_v physician_n to_o nero_n the_o emperor_n of_o rome_n it_o appear_v that_o he_o obtain_v to_o see_v and_o to_o consider_v of_o all_o the_o book_n which_o find_v in_o mithridates_n closet_n be_v translate_v into_o latin_a by_o lineus_fw-la the_o grammarian_n and_o bring_v to_o rome_n and_o it_o be_v not_o agreeable_a to_o reason_n that_o andromachus_n study_v to_o make_v a_o more_o perfect_a medicine_n then_o that_o which_o come_v under_o the_o name_n of_o mithridatium_n will_v also_o invent_v a_o other_o under_o the_o same_o name_n but_o it_o be_v very_o probable_a that_o andromachus_n with_o diligence_n peruse_v the_o recept_n of_o mithridatium_n use_v of_o mithridates_n will_v leave_v it_o in_o such_o form_n as_o mithridates_n compound_v it_o and_o devise_v a_o other_o by_o the_o same_o which_o he_o mean_v to_o make_v more_o perfect_a andromachus_n therefore_o not_o alter_v the_o description_n of_o mithridatium_n but_o leave_v it_o in_o the_o same_o form_n as_o it_o be_v find_v confect_v a_o other_o which_o he_o call_v theriaca_n and_o where_o we_o do_v read_v in_o y_z e_o 2._o de_fw-la antid_v of_o galen_n a_o other_o recept_n set_v down_o under_o the_o name_n of_o theriaca_n mithridatis_n with_o assertion_n that_o the_o king_n use_v the_o same_o yet_o it_o seem_v not_o to_o be_v y_z t_o mithridatium_n which_o be_v find_v in_o the_o closet_n of_o that_o king_n for_o all_o writer_n do_v confess_v that_o andromachus_n long_v after_o add_v to_o that_o recept_n of_o mithridates_n the_o flesh_n of_o viper_n so_o that_o mithridatium_n compound_v by_o mithridates_n have_v not_o in_o it_o the_o flesh_n of_o viper_n and_o that_o theriacle_n which_o galen_n in_o that_o place_n call_v theriaca_n mithridatis_n do_v receive_v the_o flesh_n of_o viper_n so_o it_o follow_v that_o it_o be_v not_o the_o mithridatium_n use_v of_o mithridates_n and_o he_o that_o will_v with_o diligence_n peruse_v that_o recept_n mention_v of_o galen_n by_o the_o name_n of_o theriaca_n mithridatis_n shalâ—_n find_v it_o in_o y_z e_z simples_n not_o much_o differ_v from_o theriaca_n andromachi_n and_o many_o thing_n repeat_v twice_o in_o diverse_a clause_n do_v argue_v a_o imperfection_n that_o galen_n may_v be_v think_v in_o y_z t_z place_n to_o speak_v after_o y_z e_z common_a opinion_n when_o he_o affirm_v it_o to_o be_v the_o same_o which_o mithridates_n use_v be_v in_o deed_n far_o different_a from_o that_o medicine_n wherefore_o we_o may_v reasonable_o conclude_v that_o the_o first_o recept_n transcribe_v by_o galen_n in_o 2._o de_fw-la antid_v out_o of_o andromachus_n work_v be_v in_o truth_n the_o self_n same_o that_o mithridates_n use_v and_o in_o my_o opinion_n in_o that_o respect_n the_o better_a to_o be_v like_v and_o the_o rather_o to_o be_v follow_v for_o what_o better_a assurance_n can_v we_o have_v of_o the_o true_a and_o perfect_a confection_n of_o this_o medicine_n then_o that_o which_o be_v deliver_v by_o mithridates_n and_o what_o description_n can_v more_o assure_v we_o of_o the_o effect_n of_o this_o medicine_n then_o y_z t_z composition_n which_o mithridates_n follow_v who_o first_o give_v so_o notable_a proof_n of_o the_o medicine_n and_o thereby_o the_o first_o credit_n to_o the_o same_o so_o that_o if_o by_o discourse_n of_o reason_n it_o may_v be_v prove_v that_o a_o other_o description_n be_v more_o artificial_a and_o more_o agreeable_a to_o the_o rule_n of_o confection_n of_o medicine_n yet_o in_o my_o opinion_n this_o description_n be_v the_o same_o that_o mithridates_n use_v set_v down_o happy_o by_o the_o king_n more_o according_a to_o experience_n then_o art_n be_v rather_o to_o be_v follow_v then_o any_o other_o think_v more_o cunning_o address_v nevertheless_o it_o be_v not_o to_o be_v deem_v that_o king_n mithridates_n be_v altogether_o unskylfull_a when_o many_o volume_n concern_v physic_n be_v find_v in_o his_o closet_n &_o translate_v into_o latin_a bring_v to_o rome_n and_o it_o appear_v that_o he_o take_v delight_n in_o medicinal_a matter_n have_v about_o he_o dyverse_a physician_n who_o may_v artificial_o dispense_v the_o simples_n in_o mithridatium_n and_o galen_n in_o the_o say_a book_n de_fw-fr antid_v commend_v the_o description_n of_o mithridatium_n attribute_v to_o andromachus_n whereby_o it_o appear_v that_o this_o description_n of_o mithridatium_n be_v not_o address_v altogether_o without_o art_n for_o which_o cause_n y_fw-es e_fw-it learn_v of_o our_o time_n have_v great_a reason_n to_o prefer_v that_o description_n of_o mithridatium_n before_o other_o albeit_o some_o do_v more_o esteem_v the_o composition_n of_o damocrates_n as_o with_o more_o art_n and_o more_o cunning_a dispense_v notwithstanding_o because_o it_o be_v very_o likely_a y_fw-mi t_o the_o precept_n attribute_v to_o andromachus_n as_o find_v in_o his_o book_n be_v the_o self_n same_o that_o mithridates_n use_v and_o have_v of_o many_o in_o this_o our_o country_n of_o late_a year_n be_v follow_v i_o think_v best_a in_o this_o place_n to_o express_v y_z e_o same_o as_o i_o do_v find_v it_o in_o galen_n in_o 2._o de_fw-la antid_v and_o be_v in_o many_o antidotary_n book_n allow_v which_o be_v as_o follow_v rec._n glicirrizae_fw-la Ê’_n seven_o ob_fw-la iiij_o spicae_fw-la nardi_fw-la Ê’_n seven_o ob_fw-la iij._n croci_fw-la cinnamomi_fw-la zinziberis_fw-la ana_fw-la Ê’_n seven_o ob_fw-la ij_o galbani_fw-la Ê’_n seven_o castorei_fw-la costi_fw-la ana_fw-la Ê’_n vj._n ob_fw-la ij_o scordij_fw-la iunci_fw-la odorati_fw-la
for_o then_o in_o deed_n every_o simple_a retain_v his_o own_o virtue_n opium_n may_v remit_v the_o hot_a quality_n of_o the_o rest_n at_o what_o time_n neither_o of_o these_o medicine_n be_v general_o to_o be_v use_v but_o for_o some_o special_a point_n as_o galen_n to_o provoke_v sleep_n do_v counsel_n new_a theriacle_n but_o after_o fermentation_n be_v perfect_v all_o the_o simples_n one_o alter_v the_o other_o every_o one_o have_v quality_n so_o break_v that_o not_o one_o retain_v his_o own_o nature_n then_o sure_o the_o common_a form_n result_v do_v follow_v the_o simples_n which_o do_v bear_v dominion_n and_o they_o in_o both_o these_o medicine_n be_v hot_a and_o dry_a and_o y_z e_z hot_a and_o dry_a simples_n in_o theriacle_n be_v more_o in_o number_n and_o of_o great_a force_n then_o in_o mithridalium_n as_o may_v appear_v to_o he_o that_o will_v compare_v both_o confection_n whereby_o it_o follow_v that_o the_o common_a quality_n arise_v in_o theriacle_n do_v heat_n more_o than_o that_o in_o mithridatium_n neither_o the_o increase_n of_o opium_n do_v in_o proportion_n answer_v the_o strength_n of_o heat_n in_o it_o neither_o have_v it_o any_o such_o force_n so_o great_o to_o contemper_v the_o simples_n as_o these_o man_n do_v imagine_v for_o although_o opium_n have_v special_a property_n above_o other_o medicine_n to_o induce_v sleep_n yet_o his_o cool_a quality_n of_o many_o writer_n be_v not_o account_v so_o great_a for_o it_o have_v so_o strong_a bitterness_n that_o many_o do_v suppose_v that_o it_o have_v a_o mixed_a nature_n consist_v of_o many_o hot_a part_n if_o it_o be_v true_a that_o galen_n write_v in_o his_o 5._o book_n of_o simples_n that_o all_o bitter_a thing_n be_v hot_a and_o be_v certain_a y_fw-mi t_o opium_n do_v stupefy_v &_o strong_o cause_v sleep_n it_o be_v of_o some_o infer_v y_o it_o that_o power_n do_v rather_o proceed_v of_o a_o property_n of_o substance_n than_o altogether_o depend_v of_o his_o cool_a quality_n wherefore_o it_o be_v not_o without_o reason_n affirm_v by_o learned_a man_n write_v hereof_o that_o mithridatium_n do_v not_o so_o strong_o heat_n as_o theriacle_n and_o experience_n do_v also_o confirm_v the_o same_o for_o who_o so_o use_v these_o medicine_n doubtless_o he_o shall_v find_v that_o theriacle_n right_o compound_v after_o andromachus_n description_n which_o be_v in_o all_o this_o treatise_n to_o be_v understand_v and_o be_v in_o these_o day_n of_o the_o apothecary_n most_o common_o make_v and_o so_o of_o the_o wise_a sort_n in_o most_o vulgar_a use_n do_v heat_n more_o than_o mithridatium_n which_o be_v confess_v of_o the_o writer_n comment_v upon_o the_o antidotary_n of_o nicolaus_n and_o in_o this_o our_o age_n of_o many_o learned_a man_n affirm_v for_o which_o cause_n many_o in_o these_o day_n without_o danger_n do_v use_n mithridatium_n when_o need_n require_v in_o summer_n time_n &_o hot_a season_n very_o few_o and_o seldom_o theriacle_n and_o galen_n do_v express_o forbid_v to_o gieve_v theriacle_n to_o child_n more_o safe_a therefore_o be_v the_o use_n of_o mithridatium_n then_o of_o theriacle_n not_o only_o in_o respect_n of_o the_o heat_a quality_n which_o seem_v less_o &_o more_o gentle_a in_o mithridatium_n but_o also_o in_o respect_n that_o a_o great_a quantity_n of_o opium_n be_v in_o theriacle_n for_o admit_v that_o opium_n by_o fermentation_n sustain_v great_a alteration_n notwithstanding_o y_o e_o common_a form_n of_o theriacle_n take_v some_o infection_n of_o opium_n y_fw-fr t_o some_o effect_n decline_v to_o his_o nature_n do_v also_o proceed_v and_o the_o more_o if_o that_o stupify_a and_o dormitory_n power_n in_o opium_n do_v depend_v rather_o of_o property_n of_o substance_n they_o of_o manifest_a cool_a quality_n as_o some_o do_v argue_v for_o the_o property_n of_o substance_n in_o medicine_n have_v not_o like_a alteration_n by_o fermentation_n as_o the_o manifest_a quality_n have_v by_o reaction_n we_o may_v therefore_o fear_v the_o common_a and_o often_o use_v of_o theriacle_n for_o y_o e_o quantity_n of_o opium_n in_o it_o for_o like_o reason_n often_o use_v of_o theriacle_n may_v be_v suspect_v because_o of_o the_o flesh_n of_o viper_n add_v to_o it_o as_o the_o base_a &_o ground_n of_o the_o medicine_n for_o notwithstanding_o y_fw-mi e_o great_a care_n of_o the_o place_n of_o the_o time_n of_o the_o kind_n observe_v in_o take_v and_o choose_v of_o the_o viper_n the_o diligence_n in_o prepare_v the_o care_n of_o mixture_n with_o other_o thing_n for_o the_o better_a correction_n of_o the_o malignity_n of_o y_fw-fr e_o beast_n which_o haply_o may_v remain_v in_o the_o flesh_n yet_o a_o man_n may_v doubt_v of_o some_o error_n commit_v in_o so_o dangerous_a a_o case_n and_o though_o all_o thing_n therein_o be_v ryghte_o do_v yet_o some_o little_a quality_n of_o the_o nature_n of_o y_fw-fr e_o beast_n will_v remain_v that_o a_o man_n may_v suspect_v often_o to_o use_v the_o medicine_n and_o where_o king_n mithridates_n be_v expert_a in_o physical_a matter_n it_o be_v not_o to_o be_v adjudge_v but_o that_o he_o do_v aswell_o know_v the_o nature_n of_o the_o flesh_n of_o viper_n as_o he_o know_v the_o venom_n of_o the_o beast_n so_o it_o be_v very_o likely_a that_o he_o purpose_v to_o compound_v a_o medicine_n to_o be_v often_o take_v for_o his_o safety_n against_o poison_n do_v of_o purpose_n make_v it_o without_o the_o flesh_n of_o viper_n know_v that_o if_o he_o shall_v have_v add_v that_o he_o may_v not_o with_o like_a safety_n have_v daily_o use_v y_o e_o same_o and_o what_o learned_a man_n do_v so_o often_o in_o these_o day_n counsel_n theriacle_n as_o do_v mithridatium_n and_o we_o do_v in_o this_o our_o time_n with_o less_o danger_n and_o more_o security_n for_o the_o measles_n the_o small_a pock_n the_o worm_n and_o for_o internal_a disease_n in_o child_n geve_v mithridatium_n then_o theriacle_n we_o may_v therefore_o in_o my_o opinion_n just_o conclude_v that_o mithridatium_n be_v a_o medicine_n more_o general_o to_o be_v use_v &_o may_v often_o an_o with_o more_o safety_n be_v geaven_v then_o theriacle_n of_o the_o age_n and_o keep_n of_o mithridatium_n where_o we_o have_v sufficient_o declare_v that_o compound_a medicine_n must_v have_v a_o time_n of_o fermentation_n before_o they_o be_v bring_v to_o use_v this_o place_n require_v that_o we_o do_v declare_v the_o time_n when_o mithridatium_n be_v sufficient_o ferment_v and_o come_v to_o his_o perfection_n galen_n in_o his_o book_n de_fw-fr theriaca_fw-la do_v write_v exact_o of_o the_o time_n of_o fermentation_n of_o theriacle_n affirm_v that_o it_o be_v thorough_o concoct_v in_o twelve_o year_n not_o deny_v but_o y_o t_o it_o have_v concoction_n in_o short_a time_n as_o in_o 5._o and_o in_o 7._o year_n so_o that_o we_o be_v to_o judge_v that_o theriacle_n be_v not_o sufficient_o ripe_a to_o be_v use_v before_o five_o year_n and_o in_o 7_o year_n be_v better_o digest_v &_o in_o xij_o year_n have_v his_o full_a fermentation_n and_o perfect_a concoction_n yet_o aetius_n and_o paulus_n aegineta_n do_v measure_n the_o concoction_n of_o theriacle_n in_o short_a time_n for_o aetius_n say_v that_o theriacle_n be_v ferment_v in_o xij_o month_n and_o that_o it_o may_v be_v use_v after_o one_o month_n in_o some_o case_n and_o so_o affirm_v that_o it_o endure_v to_o thirty_o year_n where_o paulus_n appoint_v y_o e_o age_n of_o theriacle_n to_o be_v twenty_o year_n therein_o he_o do_v not_o great_o differ_v from_o aetius_n for_o he_o make_v the_o term_n of_o theriacle_n to_o be_v 30_o year_n do_v also_o say_v that_o then_o it_o be_v good_a in_o light_a disease_n so_o that_o by_o aetius_n theriacle_n may_v be_v use_v after_o xij_o month_n and_o continue_v in_o good_a perfection_n to_o 20._o year_n and_o after_o decline_v that_o at_o 30._o year_n it_o be_v age_v yet_o may_v it_o be_v use_v in_o disease_n which_o be_v not_o very_o great_a our_o late_a writer_n do_v general_o better_o allow_v of_o aetius_n &_o paulus_n opinion_n for_o the_o age_n of_o theriacle_n then_o of_o galens_n and_o some_o suppose_v a_o error_n or_o fault_n in_o y_z t_z place_n in_o galen_n and_o so_o they_o do_v affirm_v y_z t_o theriacle_n be_v full_o concoct_v in_o the_o space_n of_o xij_o month_n and_o then_o may_v be_v sell_v of_o the_o apothecary_n and_o that_o the_o same_o be_v well_o keep_v will_v continue_v in_o good_a strength_n 20._o year_n and_o after_o do_v decline_v and_o wax_v weak_a and_o yet_o may_v be_v use_v when_o it_o be_v 30._o year_n old_a but_o it_o be_v then_o as_o a_o old_a man_n decay_v and_o weak_a of_o strength_n of_o mithridatium_n the_o former_a writer_n have_v set_v down_o no_o time_n of_o concoction_n leave_v to_o a_o wise_a man_n to_o determine_v of_o y_fw-fr t_o which_o be_v write_v according_o of_o theriacle_n