nor_o themselves_o their_o own_o according_a to_o vulgar_a apprehension_n for_o what_o can_v silence_n prove_v more_o than_o a_o plain_a acknowledgement_n of_o such_o a_o error_n as_o will_v not_o endure_v the_o light_n of_o reason_n nor_o reduce_v any_o contrary_a disputant_n to_o a_o incommodum_fw-la but_o leave_v a_o censure_n upon_o the_o art_n itself_o and_o all_o other_o that_o profess_v it_o as_o if_o art_n be_v only_o a_o conjecture_n and_o heal_v or_o cure_v of_o disease_n be_v but_o a_o accident_n as_o if_o cause_n have_v no_o relation_n to_o their_o effect_n nor_o the_o sublation_n of_o they_o artificial_o to_o any_o substantial_a predicament_n which_o otherwise_o have_v have_v a_o equal_a reputation_n of_o excellency_n in_o all_o age_n and_o the_o professor_n thereof_o among_o all_o nation_n witness_v very_o many_o king_n which_o have_v esteem_v the_o contemplation_n and_o practice_n of_o medicine_n as_o the_o one_o chief_a jewel_n in_o their_o crown_n as_o have_v be_v more_o large_o express_v in_o my_o former_a write_n but_o to_o return_v from_o this_o digression_n i_o shall_v resume_v my_o discourse_n of_o phlebotomy_n and_o show_v how_o unresolved_a and_o unsettle_a a_o remedy_n it_o be_v in_o this_o disease_n all_o the_o chief_a professor_n of_o medicine_n establish_v it_o upon_o the_o indication_n either_o of_o plenitude_n of_o humour_n or_o magnitude_n of_o disease_n these_o being_n most_o proper_a and_o universal_a indication_n of_o phlebotomy_n and_o although_o it_o be_v a_o general_a precept_n according_a to_o the_o doctrine_n of_o galen_n yet_o it_o be_v not_o without_o exception_n and_o more_o especial_o except_v in_o this_o case_n of_o the_o small_a pox._n because_o in_o this_o operation_n a_o retraction_n of_o the_o peccant_a humour_n from_o the_o circumference_n to_o the_o centre_n can_v be_v avoid_v which_o remedy_n must_v be_v as_o dangerous_a as_o unreasonable_a because_o no_o person_n of_o reason_n will_v allow_v a_o revulsion_n from_o a_o ignoble_a part_n to_o the_o most_o vital_a and_o noble_a part_n and_o although_o plenitude_n of_o humour_n be_v a_o indication_n for_o evacuation_n yet_o it_o do_v not_o sole_o indicate_v phlebotomy_n except_o it_o be_v a_o fullness_n and_o redundance_n of_o blood_n in_o predominance_n for_o impure_a plenitude_n be_v a_o contra-indicant_a of_o phlebotomy_n the_o blood_n offend_v more_o in_o quantity_n then_o in_o quality_n be_v the_o most_o proper_a indication_n of_o blood-letting_n and_o though_o there_o be_v some_o predominancy_n of_o blood_n yet_o blood-letting_n in_o such_o a_o case_n have_v never_o prove_v a_o curative_fw-it remedy_n nor_o do_v i_o ever_o see_v a_o sanguineous_a apoplexy_n cure_v by_o blood-letting_n and_o yet_o the_o indication_n of_o phlebotomy_n be_v proper_a yet_o not_o curative_fw-it because_o it_o be_v not_o per_fw-la se_fw-la the_o cause_n of_o the_o disease_n for_o where_o the_o cause_n be_v external_a as_o a_o confusion_n in_o such_o case_n though_o there_o be_v a_o predominancy_n of_o blood_n yet_o blood-letting_n do_v prove_v a_o remedy_n of_o no_o moment_n there_o be_v also_o a_o exception_n against_o phlebotomy_n though_o there_o be_v a_o apparent_a magnitude_n of_o disease_n as_o for_o example_n there_o be_v magnitudo_fw-la morbi_fw-la in_o a_o lucuphlegmatia_fw-la or_o dropsy_n so_o also_o in_o a_o cacexia_n and_o yet_o in_o these_o and_o such_o like_a case_n phlebotomy_n can_v be_v no_o remedy_n nor_o be_v it_o indicate_v from_o the_o magnitude_n of_o these_o disease_n in_o the_o small_a pox_n also_o there_o be_v magnitude_n of_o disease_n and_o though_o it_o be_v complicate_v with_o plethory_n of_o blood_n yet_o the_o 〈◊〉_d of_o a_o â—ein_n be_v not_o a_o proper_a or_o safe_a remedy_n especial_o from_o the_o begin_n to_o their_o eruption_n because_o the_o motion_n of_o nature_n be_v critical_a therefore_o those_o that_o practise_v phlebotomy_n upon_o the_o precept_n of_o galen_n without_o distinction_n of_o case_n must_v consequent_o incur_v the_o censure_n of_o inconsiderate_a and_o rash_a practiser_n or_o such_o as_o will_v abound_v in_o their_o own_o sense_n which_o be_v nonsense_n and_o such_o fanatic_n there_o be_v in_o medicine_n equal_a to_o those_o in_o theology_n as_o do_v appear_v by_o voluminous_a indigestion_n belch_v out_o in_o this_o age_n some_o of_o they_o mere_a ebullition_n of_o bitterness_n and_o other_o of_o heresy_n foment_v faction_n and_o mutiny_n in_o the_o school_n of_o learning_n as_o much_o as_o in_o the_o common-weal_n some_o such_o sectary_n there_o be_v in_o physic_n that_o deny_v phlebotomy_n to_o be_v a_o remedy_n in_o any_o case_n or_o disease_n such_o as_o be_v the_o offspring_n of_o vanhelmont_n other_o that_o make_v it_o the_o sole-remedy_n in_o all_o case_n and_o their_o instruction_n be_v from_o the_o mode_n of_o france_n which_o mode_n be_v of_o no_o antiquity_n in_o that_o nation_n nor_o ever_o so_o common_o use_v by_o any_o of_o their_o ancient_a professor_n which_o do_v ordain_v it_o as_o it_o be_v in_o itself_o a_o great_a remedy_n if_o proper_o adhibit_v viz._n where_o there_o be_v magnitude_n and_o violence_n of_o disease_n conjunct_a with_o plethory_n of_o blood_n and_o consist_v age_n yet_o not_o without_o distinction_n of_o cause_n and_o disease_n with_o other_o circumstance_n of_o time_n and_o clime_n and_o those_o that_o do_v read_v the_o most_o learned_a of_o that_o nation_n can_v find_v they_o no_o otherwise_o principled_a yet_o i_o have_v hear_v fernelius_n which_o i_o take_v to_o be_v a_o glory_n to_o that_o nation_n to_o have_v have_v a_o most_o sad_a censure_n by_o some_o of_o parisian_a practiser_n and_o that_o it_o have_v be_v better_a for_o their_o nation_n that_o he_o have_v be_v unborn_a i_o have_v hear_v this_o language_n in_o discourse_n but_o can_v never_o conceive_v from_o what_o part_n of_o his_o learning_n they_o extract_v their_o bitterness_n but_o to_o return_v to_o my_o theme_n of_o phlebotomy_n in_o the_o small_a pox_n in_o which_o case_n the_o agent_n stand_v only_o like_o archimedes_n in_o expectation_n of_o a_o place_n to_o fix_v his_o foot_n to_o dislodge_v the_o earthen_a globe_n for_o until_o such_o a_o assurance_n of_o certainty_n to_o depend_v upon_o do_v manifest_v itself_o there_o will_v be_v no_o wellgrounded_n assurance_n of_o cure_v this_o disease_n by_o phlebotomy_n not_o deny_v the_o practice_n upon_o just_a indication_n from_o the_o cause_n and_o disease_n right_o apprehend_v to_o be_v a_o most_o effectual_a remedy_n but_o in_o this_o case_n although_o conjunct_a with_o plenitude_n of_o blood_n which_o do_v most_o proper_o indicate_v evacuation_n yet_o this_o evacuation_n by_o blood-letting_n be_v insufficient_a because_o according_a to_o galen_n in_o his_o book_n de_fw-fr multitudine_fw-la de_fw-fr element_n de_fw-fr morbis_fw-la vulgaribus_fw-la say_v that_o blood_n be_v most_o temperate_a because_o it_o be_v a_o equal_a mixture_n of_o all_o humour_n ad_fw-la justitiam_fw-la and_o therefore_o phlebotomy_n to_o be_v a_o equal_a evacuation_n of_o all_o humour_n conjunct_a with_o natural_a spirit_n and_o by_o this_o operation_n the_o blood_n be_v leave_v in_o its_o predominancy_n according_a to_o proportion_n only_o the_o universal_a plenitude_n be_v equal_o lessen_v and_o the_o morbificall_a cause_n still_o mix_v with_o the_o remainder_n answerable_a both_o in_o quantity_n and_o quality_n to_o its_o first_o impression_n upon_o the_o whole_a mass_n so_o that_o the_o disease_n be_v not_o extinguish_v by_o this_o remedy_n but_o lessen_v in_o the_o cause_n and_o although_o according_a to_o this_o doctrine_n of_o galen_n there_o be_v a_o equal_a evacuation_n of_o humour_n yet_o the_o spirit_n do_v at_o this_o orifice_n unequal_o transpire_v for_o in_o all_o blood-letting_n there_o be_v a_o pass_n of_o fix_a and_o innate_a spirit_n with_o the_o fluent_a and_o these_o can_v come_v within_o the_o compass_n of_o equality_n because_o the_o fluent_a spirit_n be_v daily_o repair_v but_o the_o fix_v never_o otherwise_o if_o it_o come_v within_o the_o compass_n of_o repair_n man_n shall_v be_v eternal_a upon_o this_o earth_n but_o every_o evacuation_n of_o this_o nature_n do_v abreviate_v humane_a life_n and_o hasten_v old_a age_n as_o may_v be_v observe_v in_o the_o french_a child_n which_o by_o this_o frequent_a phlebotomise_v be_v wither_v in_o juvenile_n age._n therefore_o phlebotomy_n be_v not_o a_o common_a remedy_n but_o in_o such_o extremity_n as_o the_o person_n must_v lose_v some_o part_n of_o his_o subsistence_n to_o save_v the_o whole_a moreover_o in_o this_o universal_a evacuation_n there_o may_v be_v a_o expense_n of_o some_o humour_n which_o be_v necessary_a to_o be_v preserve_v in_o the_o mass_n because_o they_o be_v not_o so_o sudden_o repair_v again_o and_o from_o this_o cause_n nature_n may_v want_v a_o vehicle_n of_o motion_n and_o suffer_v tyranny_n from_o the_o disease_n as_o when_o the_o phlegmatic_a part_n of_o humour_n be_v draw_v from_o the_o choleric_a the_o bilious_a humour_n be_v leave_v as_o fire_n to_o
what_o name_n the_o small_a pox_n or_o variola_n pass_v among_o the_o ancient_n and_o sebastianus_n de_fw-fr morbis_fw-la puerorum_fw-la with_o many_o other_o writer_n be_v of_o the_o same_o opinion_n from_o who_o marcus_n antonius_n the_o florentine_a physician_n do_v differ_v quaest_n 22._o ground_v upon_o the_o authority_n of_o galen_n 4_o de_fw-fr sanitat_fw-la tuend_a say_n where_o there_o be_v a_o complication_n of_o lassitude_n with_o those_o pustules_fw-la which_o the_o grecian_a nominate_v exanthemata_fw-la from_o those_o we_o may_v soon_o discover_v the_o particular_a excrement_n which_o can_v signify_v the_o small_a pox_n because_o other_o pustules_fw-la do_v render_v the_o special_a excrement_n with_o the_o same_o distinction_n of_o pure_a choler_n burn_a choler_n or_o phlegm_n with_o their_o quality_n of_o saltness_n and_o sharpness_n therefore_o my_o endeavour_n must_v be_v to_o discourse_v of_o that_o kind_n of_o pox_n which_o assault_v humane_a body_n but_o once_o in_o the_o whole_a course_n of_o life_n except_o rare_o valeriola_n who_o memory_n be_v honourable_a do_v endeavour_n to_o prove_v the_o small_a pox_n or_o measles_n which_o appear_v critical_o in_o inpestilential_a fever_n not_o to_o be_v by_o galen_n nominate_v exanthemata_fw-la with_o who_o opinion_n i_o do_v consent_n because_o the_o appellation_n be_v of_o general_a extent_n to_o all_o kind_n of_o pustules_fw-la and_o of_o choler_n be_v as_o be_v verify_v in_o his_o book_n de_fw-fr atra_fw-la boil_n where_o he_o affirm_v in_o decease_a person_n where_o excretion_n by_o the_o low_a belly_n be_v not_o sufficient_a in_o such_o person_n the_o whole_a body_n be_v affect_v with_o pustules_fw-la quae_fw-la nigris_fw-la exanthematis_fw-la simile_n essent_fw-la circum_fw-la undique_fw-la scatuit_n and_o in_o other_o place_n he_o speak_v of_o white_a pustules_fw-la which_o pliny_n name_v papulas_fw-la and_o of_o these_o cornelius_n celsus_n make_v more_o kind_n of_o rough_a and_o sharp_a eruption_n upon_o the_o skin_n magis_fw-la &_o minus_fw-la be_v the_o only_a distinction_n of_o they_o and_o many_o modern_n conceive_v these_o pox_n to_o proceed_v from_o maternal_a menstruosity_n other_o conceive_v they_o to_o be_v intercutaneal_a ill_a juice_n or_o peccant_a humour_n ferment_v by_o a_o intense_a heat_n in_o the_o superficies_n of_o the_o skin_n which_o corrupt_a humour_n according_a to_o fracastorius_fw-la be_v generate_v by_o corrupt_a diet_n and_o therefore_o in_o his_o book_n de_fw-fr morbis_fw-la he_o place_v this_o disease_n of_o the_o small_a pox_n among_o disease_n epidemical_a and_o as_o it_o be_v a_o affect_v cutaneal_a and_o epidemical_a so_o it_o do_v infect_v all_o child_n and_o young_a person_n because_o their_o temper_n be_v proper_o more_o moist_a and_o hot_a than_o old_a age_n it_o be_v cold_a and_o dry_a in_o itself_o but_o excrementitious_o moist_a only_o by_o the_o decay_n of_o natural_a heat_n and_o altogether_o indispose_v to_o receive_v the_o impression_n of_o it_o old_a age_n be_v proper_o &_o per_fw-la se_fw-la cold_a and_o dry_a in_o temper_n if_o otherwise_o it_o be_v mirandum_fw-la in_o morbo_fw-la and_o for_o such_o wonder_n in_o disease_n i_o shall_v refer_v the_o reader_n to_o skenkius_n and_o peâ—rus_n forestus_n etc._n etc._n there_o be_v not_o want_v â—ome_v physician_n that_o be_v 〈◊〉_d of_o that_o opinion_n of_o the_o small_a pox_n that_o it_o be_v hereditary_a to_o those_o that_o be_v affect_v with_o it_o and_o not_o to_o be_v avoid_v by_o their_o natural_a issue_n let_v they_o be_v of_o any_o age_n or_o temper_n and_o therefore_o no_o more_o to_o be_v admire_v than_o the_o gout_n stone_n consumption_n with_o paralytic_a and_o hydropical_a disease_n especial_o and_o more_o general_o the_o small_a pox_n against_o who_o opinion_n fernelius_n be_v evident_o opposite_a especial_o to_o all_o physician_n that_o affirm_v the_o small_a pox_n to_o proceed_v from_o maternal_a menstruosity_n but_o especial_o cause_v by_o the_o malignity_n of_o the_o air_n conjunct_a with_o vicious_a humour_n who_o opinion_n be_v most_o reasonable_a because_o the_o vehicle_n of_o universal_a infection_n be_v the_o ambient_fw-la air_n which_o apprehend_v sudden_o all_o matter_n subject_a and_o dispose_v to_o receive_v contagion_n moreover_o when_o the_o small_a pox_n be_v universal_o spread_v they_o frequent_o usher_v in_o the_o grand_a pest_n upon_o a_o strong_a infection_n of_o the_o air_n and_o that_o it_o be_v a_o malignity_n especial_o of_o the_o air_n have_v be_v frequent_o prove_v by_o the_o creature_n of_o the_o air_n which_o have_v fall_v dead_a to_o the_o earth_n and_o kill_v by_o the_o poison_n of_o the_o air_n again_o if_o this_o disease_n be_v convey_v in_o the_o principle_n of_o nature_n from_o maternal_a blood_n which_o be_v administer_v to_o the_o production_n of_o all_o animal_n than_o there_o be_v a_o universal_a reception_n of_o this_o disease_n not_o only_o in_o humane_a nature_n but_o also_o in_o all_o animal_n who_o production_n be_v ex_fw-la semine_fw-la &_o sanguine_fw-la but_o this_o disease_n be_v apprehend_v by_o no_o subject_a matter_n indispose_v to_o receive_v the_o impression_n of_o such_o venemosity_n as_o be_v of_o this_o nature_n nor_o be_v all_o mankind_n capable_a of_o such_o reception_n although_o riverius_n will_v not_o have_v one_o of_o one_o thousand_o of_o humane_a principle_n to_o escape_v it_o yet_o in_o my_o conjecture_n there_o be_v not_o one_o of_o one_o thousand_o in_o the_o universe_n that_o have_v any_o knowledge_n or_o sense_n of_o it_o from_o their_o first_o ingress_n into_o the_o world_n to_o their_o last_o egress_n out_o of_o this_o world_n which_o can_v not_o be_v if_o it_o be_v so_o inherent_a a_o concomitant_a with_o maternal_a blood_n and_o seed_n but_o the_o small_a pox_n be_v dedicate_v to_o infant_n more_o particular_o which_o be_v most_o moist_a and_o some_o more_o than_o other_o abound_v with_o vicious_a humour_n draw_v from_o maternal_a extravagancy_n and_o corrupt_a diet_n in_o the_o time_n of_o their_o gestation_n and_o by_o this_o aptitude_n be_v well_o dispose_v to_o receive_v infection_n of_o the_o air_n upon_o the_o least_o infection_n according_a to_o epiphanius_n ferdinandus_n his_o cum_fw-la quicquid_fw-la recipiâ—ur_fw-la recipitur_fw-la in_o subjectum_fw-la benè_fw-la disposit_v they_o moreover_o the_o want_n of_o motion_n be_v a_o stagmatize_v cause_n in_o infant_n by_o which_o their_o best_a humour_n may_v be_v alter_v into_o put_v refaction_n and_o prepare_v that_o particular_a matter_n to_o a_o form_n fit_a for_o such_o matter_n for_o infant_n have_v no_o other_o exercise_n to_o digest_v their_o nutriment_n but_o cry_v according_a to_o aristotle_n and_o common_a observation_n will_v manifest_v that_o the_o most_o quiet_a infant_n be_v of_o least_o duration_n and_o most_o morbifical_a the_o cause_n of_o the_o small_a pox_n therefore_o be_v upon_o the_o corrupt_a disposition_n of_o the_o humorable_a mass_n internal_a and_o these_o two_o cause_n do_v produce_v that_o one_o effect_n which_o galen_n nominate_v obstruction_n of_o all_o distribution_n internal_a and_o transpiration_n external_a the_o permanency_n and_o continuation_n whereof_o do_v effect_v a_o ill_a habit_n and_o consequent_o all_o disease_n both_o similary_n dissimilary_a and_o common_a and_o thus_o i_o proceed_v to_o the_o sign_n of_o this_o particular_a disease_n although_o the_o sign_n by_o which_o this_o disease_n be_v signify_v and_o distinguish_v from_o other_o affect_n be_v many_o which_o be_v render_v from_o the_o greek_n arabian_n and_o latin_n yet_o from_o none_o of_o they_o more_o exact_o than_o à _fw-fr joanne_n pascalio_fw-la medico_fw-la valentino_n in_o their_o order_n the_o first_o sign_n of_o they_o be_v a_o pain_n of_o the_o back_n the_o second_o itch_a of_o the_o nose_n the_o three_o fearful_a and_o trouble_a sleep_n the_o four_o a_o compunction_n of_o the_o sensible_a and_o nervy_a part_n of_o the_o body_n the_o five_o a_o heaviness_n or_o ponderosity_n of_o the_o whole_a body_n the_o six_o a_o flourish_a colour_n in_o the_o face_n the_o seven_o be_v the_o lacrymation_n of_o the_o eye_n the_o eight_o a_o burn_a heat_n and_o fervency_n of_o the_o whole_a body_n the_o nine_o a_o gape_v yawn_v and_o stretch_v of_o the_o whole_a body_n the_o ten_o be_v a_o palpitation_n intercutaneal_a the_o eleven_o be_v a_o compression_n and_o shortness_n of_o breath_n the_o twelve_v a_o raucedo_n or_o hoarseness_n the_o thirteen_o be_v a_o thick_a spit_v from_o much_o heat_n the_o fourteen_o be_v the_o heaviness_n of_o the_o head_n the_o fifteen_o be_v the_o tremble_a of_o the_o heart_n the_o sixteen_o be_v a_o great_a siccity_n or_o drought_n and_o dryness_n of_o the_o mouth_n and_o tongue_n the_o seventeen_o be_v the_o perturbation_n of_o the_o mind_n with_o convulsive_a motion_n the_o eighteen_o be_v the_o soreness_n of_o the_o throat_n the_o nineteen_o the_o tremble_a of_o the_o hand_n and_o foot_n the_o twenty_o be_v a_o perturb_a and_o pale_a urine_n these_o be_v the_o pathognomical_a and_o proper_a sign_n of_o this_o
tyrannize_v over_o the_o remain_a humour_n and_o the_o spirit_n which_o be_v more_o apt_a to_o be_v inflame_v and_o for_o this_o reason_n a_o universal_a evacuation_n by_o phlebotomy_n in_o the_o small_a pox_n be_v and_o must_v be_v a_o doubtful_a remedy_n because_o no_o man_n can_v just_o prove_v that_o in_o a_o phlebotick_a operation_n he_o shall_v let_v out_o the_o predominant_a cause_n more_o or_o less_o or_o equal_a to_o any_o of_o the_o mixture_n in_o the_o mass_n of_o blood_n therefore_o if_o the_o principal_a scope_n of_o the_o agent_n be_v to_o relieve_v nature_n offend_v and_o oppress_v by_o the_o predominance_n and_o turgency_n of_o a_o single_a peccant_a cause_n the_o remedy_n indicate_v must_v be_v a_o particular_a correction_n separation_n and_o extinction_n of_o that_o particular_a predominance_n which_o be_v not_o to_o be_v effect_v by_o cut_v a_o vein_n because_o the_o evacuation_n be_v universal_a and_o equal_o of_o the_o whole_a mass_n of_o humour_n leave_v the_o predominant_a humour_n according_a to_o proportion_n as_o turbulent_a as_o before_o and_o consequent_o it_o can_v be_v no_o specifical_a remedy_n in_o such_o a_o case_n where_o the_o scope_n of_o cure_n be_v indicate_v from_o the_o quantity_n of_o the_o humour_n in_o predomination_n and_o thus_o i_o pass_v to_o the_o circumstance_n of_o clime_n which_o do_v prohibit_v phlebotomy_n universal_o to_o be_v use_v in_o all_o region_n i_o be_o not_o ignorant_a of_o the_o doctrine_n of_o galen_n nor_o of_o his_o precept_n in_o this_o point_n of_o phlebotomy_n nor_o of_o augenius_n his_o 17._o book_n upon_o the_o same_o subject_a and_o although_o galen_n in_o very_a many_o place_n affirm_v phlebotomy_n to_o be_v a_o universal_a and_o equal_a evacuation_n of_o the_o mix_a mass_n of_o blood_n yet_o not_o grant_v without_o his_o own_o exception_n to_o be_v a_o universal_a remedy_n in_o all_o disease_n nor_o in_o all_o region_n therefore_o i_o shall_v now_o pass_v or_o urge_v his_o own_o exception_n against_o himself_o which_o consist_v in_o the_o distinction_n of_o region_n and_o diversity_n of_o clime_n which_o as_o they_o be_v distinct_a in_o the_o degree_n of_o air_n so_o also_o distinct_a in_o their_o diet_n which_o do_v maintain_v nature_n in_o its_o perpâ—tuo_fw-la fluere_fw-la and_o as_o every_o region_n have_v a_o customary_a diet_n so_o be_v their_o customary_a or_o common_a air_n most_o agreeable_a to_o the_o inhabitant_n as_o mud_n be_v to_o eel_n and_o these_o be_v principal_o their_o subsistence_n and_o much_o disorder_v upon_o any_o alteration_n of_o their_o air_n and_o diet_n and_o if_o this_o accident_n have_v not_o happen_v to_o william_n parr_n of_o our_o own_o nation_n his_o principle_n of_o nature_n may_v have_v last_v to_o this_o day_n unquenched_a and_o it_o be_v a_o large_a vulgar_a error_n to_o defend_v the_o death_n of_o any_o person_n to_o be_v just_a according_a to_o the_o power_n of_o his_o principle_n nor_o can_v any_o person_n persuade_v sir_n thomas_n more_o upon_o the_o scaffold_n but_o if_o it_o have_v be_v the_o king_n pleasure_n he_o may_v have_v live_v many_o more_o year_n upon_o the_o principle_n of_o nature_n but_o these_o change_n be_v accidental_a but_o as_o every_o distinct_a region_n have_v their_o particular_a air_n and_o diet_n so_o be_v the_o remedy_n or_o medicinal_a ingression_n of_o their_o own_o clime_n most_o proper_a for_o their_o common_a and_o vulgar_a distemper_n and_o those_o remedy_n will_v be_v more_o specifical_o sanative_a in_o that_o region_n than_o any_o other_o aliuâ—de_fw-la or_o contract_v from_o another_o clime_n and_o out_o of_o a_o general_a observation_n galen_n have_v except_v against_o his_o general_a precept_n of_o phlebotomy_n in_o his_o 9th_o book_n de_fw-fr methodo_fw-la medendi_fw-la where_o he_o say_v in_o the_o extraction_n of_o blood_n there_o be_v many_o scope_n observable_a and_o to_o be_v consider_v by_o the_o physician_n viz._n custom_n strength_n of_o spirit_n consist_v age_n with_o the_o temper_n of_o the_o region_n and_o place_n of_o habitation_n as_o also_o the_o time_n of_o the_o year_n with_o the_o state_n of_o the_o heaven_n and_o by_o reason_n of_o these_o circumstance_n though_o blood-letting_n be_v necessary_a yet_o without_o a_o necessity_n of_o coaction_n not_o to_o be_v adhibit_v and_o if_o there_o be_v such_o a_o necessity_n it_o be_v to_o be_v draw_v spare_o and_o with_o great_a consideration_n as_o by_o these_o expression_n of_o galen_n the_o whole_a universe_n may_v take_v cognizance_n that_o as_o he_o esteem_v phlebotomy_n to_o be_v a_o grand_a remedy_n so_o he_o advise_v the_o use_n of_o it_o with_o as_o great_a circumspection_n and_o judgement_n and_o the_o nonestablishment_n of_o this_o remedy_n neither_o by_o the_o ancient_a nor_o modern_a professor_n of_o heal_a be_v the_o cause_n of_o so_o much_o difference_n in_o consultation_n every_o man_n embrace_v his_o own_o commentary_n upon_o it_o which_o make_v the_o remedy_n more_o doubtful_a otherwise_o it_o be_v according_a to_o gantius_fw-la the_o portugal_n physician_n the_o most_o pleasant_a and_o sudden_a remedy_n in_o all_o disease_n for_o it_o be_v quick_o do_v and_o with_o as_o little_a trouble_n and_o pain_n and_o now_o i_o pass_v to_o the_o circumstance_n of_o time_n to_o be_v observe_v in_o this_o operation_n riverius_n i_o conceive_v among_o all_o the_o modern_n to_o be_v the_o great_a assertor_n of_o phlebotomy_n in_o variolis_n &_o morbillis_fw-la which_o be_v the_o small_a pox_n and_o measles_n and_o yet_o without_o the_o circumstance_n of_o time_n age_n and_o plethory_n of_o blood_n he_o will_v not_o adhibit_v phlebotomy_n nor_o upon_o redundance_n of_o blood_n if_o there_o appear_v any_o sign_n of_o their_o eruption_n neither_o do_v he_o admit_v of_o any_o inordinate_a sleep_n si_fw-mi pustulae_fw-la erumpunt_fw-la and_o for_o this_o reason_n quia_fw-la motus_fw-la motui_fw-la contrarius_fw-la for_o sleep_n do_v colligate_v the_o sense_n and_o retract_v the_o spirit_n and_o humour_n to_o the_o centre_n and_o for_o the_o same_o reason_n phlebotomy_n be_v prohibit_v and_o the_o same_o author_n say_v those_o that_o will_v begin_v the_o cure_n with_o blood-letting_n must_v be_v sure_a that_o the_o foresay_a indication_n of_o age_n and_o redundance_n of_o blood_n be_v complete_v moreover_o it_o be_v very_o rare_a to_o meet_v with_o such_o a_o conjunction_n of_o indicant_o plethory_n itself_o according_a to_o the_o proper_a signification_n be_v a_o fullness_n and_o redundance_n of_o the_o pure_a blood_n and_o such_o a_o redundance_n as_o be_v ad_fw-la distentionem_fw-la vasorum_fw-la and_o very_o rare_o discover_v in_o disease_n &_o therefore_o the_o remedy_n doubtful_a and_o be_v uncertain_a it_o must_v be_v rashness_n or_o debility_n of_o intellect_n to_o apply_v such_o remedy_n the_o same_o author_n say_v also_o that_o if_o the_o physician_n shall_v not_o be_v invite_v at_o the_o first_o ebullition_n when_o this_o disease_n be_v in_o its_o first_o firmentation_n and_o before_o there_o be_v any_o signification_n of_o eruption_n or_o very_o few_o in_o number_n and_o quantity_n that_o at_o such_o time_n phlebotomy_n may_v be_v profitable_a and_o in_o the_o next_o line_n contradict_v himself_o diametrical_o where_o he_o say_v upon_o the_o eruption_n of_o the_o pustules_fw-la the_o fervency_n and_o symptom_n be_v abate_v and_o the_o whole_a operation_n be_v leave_v to_o the_o motion_n of_o nature_n which_o be_v then_o propel_v the_o cause_n to_o the_o skin_n from_o the_o centrall_a part_n to_o the_o circumferential_a and_o then_o phlebotomy_n be_v unnecessary_a and_o of_o no_o use_n again_o the_o same_o author_n affirm_v that_o if_o this_o pustulous_a eruption_n be_v intense_a and_o conjunct_a with_o a_o difficulty_n of_o breathe_v it_o be_v a_o sign_n that_o nature_n be_v onerate_v or_o overburden_a and_o therefore_o blood-letting_n be_v to_o be_v ordain_v for_o disoneration_n of_o nature_n and_o enable_v it_o to_o encounter_v the_o remainder_n which_o be_v reasonable_a if_o such_o a_o part_n of_o the_o onerate_a humour_n may_v sole_o &_o per_fw-la se_fw-la be_v extract_v without_o the_o loss_n of_o spirit_n for_o the_o support_n ofspirit_n be_v the_o principal_a scoâ—e_n of_o cure_n in_o this_o disease_n which_o be_v no_o way_n effect_v by_o blood-letting_n therefore_o this_o practice_n be_v insignificant_a otherwise_o the_o argument_n will_v be_v acceptable_a to_o all_o logical_a person_n and_o as_o inacceptable_a to_o the_o whole_a sect_n of_o galenist_n which_o affirm_v phlebotomy_n to_o be_v a_o equal_a evacuation_n of_o all_o humour_n with_o fix_v and_o fluent_a spirit_n which_o be_v the_o principal_a prohibition_n of_o this_o practice_n in_o this_o case_n otherwise_o upon_o a_o universal_a oneration_n it_o be_v reasonable_a disburthen_v of_o nature_n and_o proper_o indicate_v if_o seasonable_o administer_v and_o upon_o a_o critical_a motion_n but_o to_o conclude_v with_o the_o determination_n of_o this_o author_n he_o in_o one_o worâ—_n say_v blood-letting_n in_o the_o