of his Beames haue wasted and dissipated into Aire this pestiferous dew hanging and abiding vpon boughes and leaues of Trees Herbs Corne and Fruits But on the contrarie that Pestilence which proceeds from some maligne qualitie from aboue by reason of euill and certaine coniunction of the Starres is more hurtfull to Men and Birds as those who are neerer to Heauen CHAP. VI. By vsing what cautions in Aire and Dyet one may preuent the Plague HAuing declared the signes fore-shewing a Pestilence now we must shew by what meanes we may shun the imminent danger thereof and defend our selues from it No preuention seemed more certaine to the Ancients then most speedily to remoue into places farre distant from the infected place and to be most slow in their returne thither againe But those who by reason of their businesse or employments cannot change their habitation must principally haue care of two things The first is that they strengthen their Bodyes and the principall parts thereof against the daily imminent inuasions of the Poyson or the pestiferous and venenate Aire The other that they abate the force of it that it may not imprint its virulencie in the Body which may be done by correcting the excesse of the qualitie inclining towards it by the opposition of its contrarie For if it be hotter then is meet it must be tempered with cooling things if too cold with heating things yet this will not suffice For we ought besides to amend and purge the corruptions of the venenate malignitie diffused through it by smels and perfumes resisting the Poyson thereof The Body will be strengthened and more powerfully resist the infected Aire if it want excrementitious humors which may be procured by purging and bleeding and for the rest a conuenient dyet appointed as shunning much varietie of Meats and hot and moyst things and all such which are easily corrupted in the Stomacke and cause obstructions such as those things which be made by Comfit-makers we must shun satietie and drunkennesse for both of them weakens the Powers which are preserued by the moderate vse of Meats of good iuice Let moderate exercises in a cleere Aire and free from any venemous tainture preceed your Meales Let the Belly haue due euacuation either by Nature or Art Let the Heart the seat of Life and the rest of the Bowels be strengthened with Cordials and Antidotes applyed and taken as we shall here-after shew in the forme of Epithemes Ointments Emplasters Waters Pilles Powders Tablets Opiates Fumigations and such like Make choyce of a pure Aire and free from all pollution and farre remote from stinking places for such is most fit to preserue life to recreate and repaire the Spirits whereas on the contrarie a cloudy or mistie Aire and such as is infected with grosse and stinking vapours duls the Spirits deiects the Appetite makes the Body faint and ill coloured oppresses the Heart and is the breeder of many diseases The Northern Wind is healthfull because it is cold and dry But on the contrarie the Southern Wind because it is hot and moyst weakens the Body by sloth or dulnesse opens the Pores and makes them peruious to the pestiferous malignitie The Western Wind is also vnwholsome because it comes neere to the nature of the Southern wherefore the Windowes must be shut vp on that side of the House on which they blow but opened on the North and East side vnlesse it happen the Plague come from thence Kindle a cleere Fire in all the Lodging Chambers of the House and perfume the whole House with Aromaticke things as Frankensence Myrrhe Benzoine Ladanum Styrax Roses Mirtle-leaues Lauender Rosemary Sage Sauory Wild Time Marierome Broome Pine Apples peeces of Firre Iuniper Berries Cloues Perfumes and let your Cloathes be aired in the same There be some who thinke it a great preseruatiue against the pestilent Aire to keepe a Goat in their houses because the capacitie of the Houses filled with the strong sent which the Goat sends forth prohibits the entrance of the venemous Aire which same reason hath place also in sweet smels and besides it argues that such as are hungry are apter to take the Plague then those who haue eaten moderately for the Body is not onely strengthened with Meat but all the passages thereof are filled by the vapours diffused from thence by which otherwise the infected Aire would find a more easie entrance to the Heart Yet the common sort of People yeeld another reason for the Goat which is That one ill sent driues away another as one wedge driues forth another which calles to my mind that which is recorded by Alexander Benedictus that there was a Scythian Physition which caused a Plague arysing from the infection of the Aire to cease by causing all the Dogges Cats and such like Beasts which were in the Citie to be hilled and casting their Carcasses vp and downe the Streets that so by the comming of this new putrid vapour as a stranger the former pestiferous infection as an old guest was put out of its Lodging and so the Plague ceased For Poysons haue not onely an antipathy with their Antidotes but also with some other Poysons Whilst the Plague is hot it is not good to stirre out of doore before the rysing of the Sunne wherefore we must haue patience vntill he haue cleansed the Aire with the comfortable light of his Beames and dispersed all the foggy and nocturnall pollutions which commonly hang in the Aire in dirtie and specially in low places and Valleys All publike and great meetings and assemblyes must be shunned If the Plague begin in Summer and seeme principally to rage helped forward by the Summers heat it is the best to performe a Iourney begun or vndertaken for performance of necessarie affaires rather vpon the night time then on the day because the Infection takes force strength and subtiletie of substance by which it may more easily permeate and enter in by the heat of the Sunne but by night Mens Bodies are more strong and all things are more grosse and dense But you must obserue a cleane contrarie course if the malignitie seeme to borrow strength and celeritie from coldnesse But you must alwayes eschew the Beames of the Moone but specially at the full For then our Bodyes are more languid and weake and fuller of excrementitious humors Euen as Trees which for that cause must be cut downe in their season of the Moone that is in the decrease thereof After a little gentle walking in your Chamber you must presently vse some meanes that the principall parts may be strengthened by suscitating the heat and Spirits and that the passages to them may be filled that so the way may be shut vp from the Infection comming from without Such as by the vse of Garlike haue not their Heads troubled nor their inward parts inflamed as Countrey people and such as are vsed to it to such there can be no more certaine preseruatiue and antidote against the pestiferous
respect vnto his custome age the region and the time for through emptinesse there is great danger lest that the venomous matter that is driuen out to the superficiall parts of the bodie should be called backe vnto the inward parts by an hungrie stomacke and the stomacke it selfe should bee filled with choloricke hot thinne and sharpe excrementall humors whereof commeth biting of the stomacke and gripings in the guttes CHAP. XIV What drinke the Patient infected ought to vse IF the Feauer be great and burning the patient must abstain from wine vnlesse that he be subiect to swounding and he may drink the Oxymell following in stead thereof Take of fair water three quarts wherin boile foure ounces of hony vntill the third part bee consumed scumming it continually then straine it and put it into a clean vessell and adde thereto foure ounces of vineger and as much cynamon as will suffice to giue it a taste Or else a sugered water as followeth Take two quarts of fair water of hard sugar sixe ounces of cynamon two ounces straine it through a woollen bagge or cloth without anie boiling and when the patient will vse it put thereto a little of the iuice of Citrons The syrupe of the iuce of Citrons excelleth amongst all others that are vsed against the Pestilence The vse of the Iulep following is also verie wholesome Take of the iuice of Sorrell well clarified halfe a pinte of the iuice of Lettuce so clarified foure ounces of the best hard Sugar one pound boile them together vnto a perfection let them be strained and clarified adding a little before the end a little vineger let it be vsed betweene meales with boyled water or with equall portions of the water of Sorrell Lettuce Scabious and Buglosse or take of this former described Iulep strained and clarified foure ounces let it be mixed with one pound of the forenamed cordiall waters and boile them together a little And when they are taken from the fire put thereto of yellow Sanders one dram of beaten Cinamon halfe a dram straine it through a cloth when it is cold let it bee giuen vnto the patient to drinke with the iuice of Citrons Those that haue accustomed to drinke Sider Perrie Beere or Ale ought to vse that drinke still so that it be clear transparent and thinne and made of those fruits that are somewhat tarte for troubled and dreggish drinke doth not onely engender grosse humors but also crudities windinesse and obstructions of the first region of the bodie whereof comes a feauer Oxycrate being giuen in manner following doth asswage the heate of the feauer and represse the putrefaction of the humors and the fiercenesse of the venome and also expelleth the water through the veines if so be that the patients are not troubled with spitting of bloud cough yexing and altogether weake of stomacke for such must auoid all tart things Take of faire water one quart of white or red Vineger three ounces of fine Suger foure ounces of Sirup of Roses two ounces boile them alittle and then giue the patient thereof to drinke Or Take of the iuice of Lemons and Citrons of each halfe an ounce of iuice of soure Pomegranats two ounces of the water of Sorrell and Roses of each one ounce of fair water boiled as much as shall suffice make therof a Iulep and vse it between meales Or take of Sirup of Lemons and of red Currance of each one ounce of the water of Lillies foure ounces of faire water boiled halfe a pinte make therof a Iulep Or Take of the syrups of water Lillies and Vineger of each halfe an ounce dissolve it in fiue ounces of the water of sorrell of faire water one pinte make thereof a Iulep But if the patient bee young and haue a strong and good stomacke and choloricke by natnre I thinke it not vnmeete for him to drinke a full and large draught of fountaine water cold for that is effectuall to restraine and quench the heate of the feauer and contrariwise they that drinke cold water often and a verie small quantitie at a time as the Smith doth sprinkle water on the fire at his forge doe increse the heate and burning and thereby make it endure the longer Therefore by the iudgement of Celsus when the disease is in the chiefe increase and the patient hath endured thirst for the space of three or foure dayes cold water must be giuen vnto him in great quantitie so that hee may drinke past his satietie that when his belly and stomacke are filled beyond measure and sufficiently cooled he may vomit Some doe not drinke so much thereof as may cause them to vomite but do drinke euen vnto satietie and so vse it for a cooling medicine but when either of these is done the patient must be couered with many clothes and so placed that he may sleepe and for the most part after long thirst and watching and after long fulnesse and long and great heate sound sleepe commeth by which great sweat is sent out and that is a present helpe But thirst must sometimes bee quenched with little peeces of Melons Gourds Cucumbers with the leaues of Lettuce Sorrell and purslane made moist or soked in cold water or with a little square peece of a Citron Lemon or Orange macerated in Rose water and sprinkled with sugar and so held in the mouth and then changed But if the patient be aged his strength weake phlegmaticke by nature and giuen to wine when the state of the feauer is somewhat past and the chiefe heate beginning to asswage he may drinke wine verie much delayed at his meate for to restore his strength and to supply the want of the wasted Spirits The patient ought not by anie meanes to suffer great thirst but must mitigate it by drinking or else allay it by washing his mouth with Oxicrate and such like and hee may therein also wash his hands and his face for that doth recreate the strength If the Fluxe or Laske troubel him he may verie well vse to drinke steeled water and also boiled milke wherein many stones comming red hot out of the fire haue beene manie times quenched For the drinesse and roughnesse of the mouth it is verie good to haue a cooling moistening and lenifying lotion of the mucilaginous water of the infusion of the seedes of Quinces Psilium id est Flea-wurt adding thereto a little Camphyre with the water of Plantaine and Roses then cleanse and wipe out the filth and then moisten the mouth by holding therein a little oyle of sweete Almonds mixed with a little sirup of Violets If the roughnesse doe breede or degenerate into Vlcers they must be touched with the water of the infusion of sublimate or Aqua fortis CHAP. XV. Of Antidotes to be vsed in the Plague NOw we must entreate of the proper cure of this disease which must bee vsed as soone as may bee possible because this kinde of poison in swiftnesse exceedes the celeritie of the medicine
applied therefore if the veines swell the face waxe fierie red if the arteries of the temples beate strongly if the patient can verie hardly breath by reason of a weight in his stomacke if his spittle be bloudie then ought hee to be let bloud without delay for the causes before mentioned It seemes best to open the liuer veine on the left arme whereby the heart and the spleene may be better discharged of their abundant matter yet bloud letting is not good at all times for it is not expedient when the bodie beginneth to waxe stiffe by reason of the comming of the Feuer for then by drawing backe the heate and spirits inwardly the outward parts beeing destitute of bloud waxe stiffe and cold therefore bloud cannot bee letten then without great losse of the strength and perturbation of the humors And it is to bee noted that when those plethoricke causes are present there is one Indication of bloud-letting in a simple pestilent Feauer and another in that which hath a Bubo id est a Botch or a Carbuncle ioined therewith For in one or both of these being ioined with a vehement and strong burning Feuer bloud must bee letten by opening the veine that is neerest vnto the tumor or swelling against nature keeping the straightnesse of the fibres that this being open the bloud might be drawne more directly from the part affected for all and euerie retraction of putrified bloud vnto the noble parts is to bee auoided because it is noisome and hurtfull to nature and to the patient Therefore for examples sake admit the patient bee plethoricke by repletion which is called Ad vasa id est vnto the vessells and Ad vires id est vnto the strength and therewithall he hath a tumor that is pestilent in the parts belonging vnto his head or necke the bloud must be let out of the cephalicke or median veine or out of one of their branches dispersed in the arme on the greened side But if through occasion of fatt or any other such like cause those veines doe not appeare in the arme there bee some that giue counsell in such a case to open the veine that is betweene the forefinger and the thombe the hand being put into warme water whereby that veine may swell and be filled with bloud gathered thither by meanes of the heate If the tumor bee vnder the arme-hole or about those places the liuer veine or the median must be opened which runneth alongst the hand if it bee in the groine the veine of the hamme or Saphena or any other veine aboue the foote that apreareth well but alwaies on the greeued fide And phlebotomie must bee performed before the third day for this disease is of the kinde or nature of sharpe diseases because that within foure and twentie houres it runneth past helpe In letting of bloud you must haue consideration of the strength You may perceiue that the patient is readie to swound when that his forehead waxeth moist with a small sweate sodainely arising by the aking or paine at the stomacke with an appetite to vomite and desire to go to stoole gaping blacknesse of the lippes and sodaine alteration of the face vnto palenesse and lastly most certainely by a small and slow pulse and then you must lay your finger on the veine and stop it vntill the patient come to himselfe againe either by nature or else restored by Arte that is to say by giuing vnto him bread dipped in wine or anie other such like thing then if you haue not taken bloud enough you must let it goe againe and bleede so much as the greatnesse of the disease or the strength of the patient will permit or require which being done some one of the Antidotes that are prescribed before will be verie profitable to be drunk which may repaire the strength and infrigne the force of the malignitie CHAP. XVII Of purging medicines in a pestilent disease IF you call to minde the proper indications purging shall seeme necessarie in this kinde of disease and that must be prescribed as the present case and necessitie requireth rightly considering that the disease is sodaine and doth require medicines that may with all speede driue out of the bodie the hurtfull humor wherein the noisome qualitie doth lurke and is hidden which medicines are diuerse by reason of the diuersity of the kinde of the humor and the condition or temperature of the patient For this purpose sixe graines of Scammonie beaten into pouder or else tenne graines are commonly ministred to the patient with one dramme of Treacle Also pils may bee made in this forme Take of Treacle and Mithridate of each one dramme of Sulphur vinum finely poudered halfe a dram of Diagridium foure graines make thereof Pils Or Take three drams of Alloes of Myrhe and Saffron of each one dramme of white Hellebore and Asarabacca of each foure scruples make thereof a masle with old Treacle and let the patient take foure scruples thereof for a dose three houres before meate Ruffus his Pils may be profitably giuen to those that are weake The ancient Physitions haue greatly commended Agarick for this disease because it doth draw the noisome humors out of all the members and the vertues thereof are like vnto those of Treacle for it is thought to strengthen the heart and to draw out the malignitie by purging To those that are strong the weight of two drammes may be giuen and to those that are more weake halfe a dramme It is better to giue the infusion in a decoction than in substance for beeing elected and prepared truely into Trochises it may bee called a most diuine kinde of medicine Antimonium is highly praised by the experience of many but because I know the vse thereof is condemned by the counsell and decree of the Schoole of Physitions at Paris I will here cease to speake of it Those medicines that cause sweates are thought to excell all others when the Pestilence commeth of the venemous ayre among whom the efficacie of that which followeth hath beene proued to the great good of manie in that Pestilence which was lately throughout all Germanie as Matthias Rodler Chauncellor to Duke George the Count Palatine signified vnto mee by letters They doe take a bundle of Mugwort and of the ashes thereof after it is burnt they make a lye thereof with foure pints of water then they doe set it ouer the fier and boile it in a vessell of earth well leaded vntill the liquor be consumed the earthy dregges falling vnto the bottome like vnto salt wherof they make Trochises of the weight of a crowne of gold then they dissolue one or two of those Trochises according to the strength of the patient in good Muskadine and giue it the patient to drinke and let him walke after that he hath drunk it for the space of halfe an houre then lay him in his bedde and there sweate him two or three houres and then hee will vomite and his belly will
tied with bands and sponges wet in Oxycrate must be put vnder the arme-holes cupping-glasses must be applied vnto the dugges the region of the liuer and spleene and you must put into the nostrels the doune of the Willow tree or anie other astringent medicine incorporated with the haires pluckt from the flanke belly or throat of a Hare bole Armenicke Terra sigillata the iuice of Plantain and Knotgrasse mixed together and furthermore the patient must be placed or laied in a coole place But if the pain be nothing mitigated notwithstanding all these fluxes of bloud wee must come to medicines that procure sleepe whose formes are these Take of greene Lettuce one handfull flowers of water Lillies and Violets of each two pugils one head of white Poppy bruised of the foure cold seedes of each two drams of Liquoris and Raisons of each one dramme make thereof a decoction and in the straining dissolue one ounce and an halfe of Diacodion make thereof a large potion to bee giuen when they goe to rest Also a Barly-creame may bee prepared in the water of water Lillies and Sorrell of each two ounces adding thereto sixe or eight graines of Opium of the foure cold seedes and of white Poppie seedes of each halfe an ounce and let the same bee boiled in broths with Lettuce and Purslane also the Pils de Cynoglosso idest Hounds tongue may be giuen Clisters that prouoke sleepe must be vsed which may be thus prepared Take of Barly-water halfe a pinte oile of Violets and water-Lillies of each two ounces of the water of Plantaine and Purselaine or rather of their iuices three ounces of Camphire seuen graines and the whites of three egges make thereof a Clister The head must be fomented with Rose-vineger the haire being first shauen away leauing a double cloth wet therein on the same and often renewed Sheepes lungs taken warme out of the bodies may bee applied to the head as long as they are warme Cupping-glasses with scarrification and without scarrification may be applied vnto the necke and shoulder-blades The armes and legges must bee strongly bound being first well rubbed to diuert the sharpe vapours and humors from the head Frontals may also bee made on this manner Take of the oyle of Roses and water-Lillies of each two ounces of the oile of Poppey halfe an ounce of Opium one dramme of Rose-vineger one ounce of Camphire halfe a dram mixe them together Also Nodules may bee made of the flowers of Poppies Henbane water-Lillies Mandrakes beaten in Rose-water with a little Vineger and a little Camphire and let them be often applied to the nostrels for this purpose Cataplasmes also may bee laid to the forehead As Take of the mucilage of the seedes of Psilium id est Fleawort and Quince seedes extracted in Rose-water three ounces of Barly meale foure ounces of the pouder of Rose leaues the flowers of water-Lillies and Violets of each halfe an ounce of the seedes of Poppies and Purflaine of each two ounces of the water and vineger of Roses of each three ounces make thereof a Cataplasine and apply it warme vnto the head Or Take of the iuice of Lettuce water-Lillies Henbaine Purselaine of each halfe a pinte of Rose leaues in pouder the seedes of Poppie of each halfe an ounce oyle of Roses three ounces of Vineger two ounces of Barly meale as much as shall suffice make thereof a Cataplasme in the forme of a liquid Pultis When the heate of the head is mitigated by these medicines the inflammation of the braine asswaged we must come vnto digesting and resoluing fomentations which may disperse the matter of the vapours But commonly in paine of the head they doe vse to binde the forehead and hinder part of the head verie strongly which in this case must bee auoided CHAP. XIX Of the Erruptiou and spotts which commonly are called by the name of Purples and Tokens IN Pestilent feauers the skinne is marked and variegated in diuerse places with spotts like vnto the bitings of Fleas or Gnats which are not alwaies simple but many times arise in forme like vnto a graine of millet The more spots appeare the better it is for the patient they are of diuerse colours according to the virulency of the malignity and condition of the matter as red yellow browne violet or purpule blew blacke And because for the most part they are of a purple colour therefore wee callthem Purples Others call them Lenticulae because they haue the colour and forme of lentills They are also called Papiliones i Butterflies because they doe suddainly seaze or fall vpon diuerse regions of the body like vnto winged Butterflies sometimes the face sometimes the armes and leggs and sometimes all the whole body oftentimes they doe not onely affect the vpper part of the skinne but goe deeper into the flesh specially when they proceed of matter that is grosse and adust They doe sometimes appeare great and broad affecting the whole arme legge or face like vnto an Erysipelas to conclude they are diuerse according to the variety of the humour that offends in quality or quantity If they are of a purple or blacke colour with often sounding and sinke in sodainly without any manifest cause they foreshew death The cause of the breaking out of those spotts is the working or heate of the bloud by reason of the cruelty of the venom receiued or admitted They often arise at the beginning of a Pestilent feauer many times before the breaking out of the Sore or Botch or Carbuncle and many times after but then they shew so greata corruption of the humors in the body that neither the Sores nor Carbuncles will suffice to receaue them and therefore they appeare as fore-runners of death Sometimes they breake out alone without a Botch or Carbuncle which if they be redde and haue no euill Symptomes ioyned with them they are not wont to proue deadly they appeare for the most part on the third or fourth day of the dissease and sometimes later and sometimes they appeare not before the patient bee dead because the working or heate of the humors being the ofspring of putrefaction is not as yet restrayned and ceased Wherefore then principally the putrid heate which is greatest a little before the death of the patient driues the excrementall humors which are the matter of the spotts vnto the skin or else because nature in the last conflict hath contended with some greater endeuour then before which is common to all things that are ready to dye a little before the instant time of death the Pestilent humor being presently driuen vnto the skinne and nature thus weakened by this extreame conflict falleth downe prostrate and is quite ouerthrowne by the remnant of the matter CHAP. XX. Of the cure of Eruptions and Spotts YOu must first of all take heede lest you driue in the humor that is comming outwards with repercussiues Therefore beware of cold all purging things Phlebotomy and drowsie or sound
sleeping For all such things do draw the humors inwardly and worke contrary to nature But it is better to prouoke the motion of nature outwardly by applying of drawing medicines outwardly and ministring medicines to prouoke sweate inwardly for otherwise by repelling and stopping the matter of the eruptions there will be great danger lest the heart be oppressed with the aboundance of the venome flowing backe or else by turning into the belly it inferres a mortall bloody flixe which discommodities that they may be auoyded I haue thought good to set downe this remedy whose Efficacy I haue knowne and proued many times and on diuerse persons when by reason of the weaknes of the expulsiue faculty and the thicknes of the skinne the matter of the spotts cannot breake forth but is constrayned to surke vnder the skinne lifting it vp into bunches and knobbes I was brought vnto the inuention of this remedy by comparison of the like For when I vnderstood that the essence of the French Poxs and likewise of the Pestilence consisted in a certaine hidden virulency and venemous quality I soone descended vnto that opinion that euen as by the anoynting of the body with the vnguent compounded of Quicksiluer the grosse clammie humors which are fixed in the bones and vnmoueable are dissolued relaxed and drawen from the center into the superficiall parts of the body by strengthening and stirring vp the expulsiue faculty and euacuated by sweating and fluxing at the mouth That so it should come to passe in Pestilent feauers that nature being strengthened with the same kind of vnction might vnloade her selfe of some portion of the venemous and Pestilent humor by opening the pores and passages and letting it breake forth into spotts and pustles and into all kinde of eruptions Therefore I haue annoynted many in whom nature seemed to make passage for the venemous matter very slowly first loosing their belly with a Clister and then giuing them Treacle water to drinke which might defend the vitall faculty of the heart but yet not distende the stomacke as though they had had the French Poxe and I obtained my expected purpose in stead of the Treacle water you may vse the decoction of Guaiacum which doth heate dry prouoke sweat and repell putrefaction adding thereto also vineger that by the subtletie thereof it may pearce the better and withstand the putrefaction This is the description of the vnguent Take of Hoggs grease one pound boyle it a little with the leaues of Sage Time Rosmary of each halfe an handfull straine it and in the straining extinguish fiue ounces of Quicksiluer which hath bin first boyled in Vineger with the forenamed herbs of Sal Nitrum 3 drams the yelkes of three eggs boyled vntill they be hard of Treacle and Mithridate of each halfe an ounce of Venice Turpentine oile of Scorpions and Bayes of each three ounces incorporate them altogether in a morter and make thereof an vnguent wherewith annoynt the patients arme-hooles and groine auoyding the parts that belong to the head breast and backe bone then let him be layed in his bed and couered warme and let him sweat there for the space of two houres and then let his body be wiped and clensed and if it may bee let him be layed in another bed and there let him be refreshed with the broth of the decoction of a Capon reare Eggs and with such like meates of good iuyce that are easie to be concocted and digested let him be anointed the second and the third day vnlesse the spotts appeare before If the patient fluxe at the mouth it must not be stopped when the spotts and pustles doe all appeare and the patient hath made an end of sweating it shall be conuenient to vse diureticke medicines for by these the remainant of the matter of the spotts which happely could not all breath forth may easily be purged and auoyded by the vrine If any noble or gentlemen refuse to be annoynted with this vnguent let them be inclosed in the body of a Mule or Horse that is newly killed and when that is cold let them be layed in another vntill the pustles and eruptions doe breake forth being drawne by that naturall heate For so Matthiolus writeth that Valentinus the sonne of Pope Alexander the sixt was deliuered from the danger of most deadly poyson which he had drunke CHAP. XXI Of a Pestilent Bubo or Plague-sore A Pestilent Bubo is a tumor at the beginning long and moueable and in the state and full perfection copped and with a sharpe head vnmoueable and fixed deepely in the glandules or kernels by which the braine exonerates it selfe of the venemous and pestiferous matter into the kernells that are behinde the eares and in the necke the heart into those that are in the arme-hooles and the liuer into those that are in the groine that is when all the matter is grosse and clammy so that it cannot bee drawen out by spotts and pustles breaking out on the skin and so the matter of a Carbuncle is sharpe and so feruent that it maketh an Eschar on the place where it is fixed In the beginning while the Bubo is breeding it maketh the patient to feele as it were a coard or rope stretched in the place or a hardened nerue with pricking payne and shortly after the matter is raised vp as it were into a knob and by little and little it groweth bigger and is enflamed these accidents before mentioned accompanying it If the tumor be red and encrease by little and little it is a good and salutary signe but if it be liuide or blacke and come very slowly vnto its iust bigness it is a deadly signe It is also a deadly signe if it encrease sodainly and come vnto his iust bigness as it were with a swift violence as in a moment haue all the Symptomes in the highest excesse as pain swelling and burning Buboes or Sores appeare sometimes of a naturall colour like vnto the skinne and in all other things like vnto an oedematous tumor which notwithstanding will sodainly bring the patient to destruction like those that are liuide and blacke wherefore it is not good to trust too much to those kindes of tumors CHAP. XXII Of the cure of Buboes or Plague-sores SO soone as the Bubo appeares apply a Cupping-glasse with a great flame vnto it vnlesse it bee that kinde of Bubo which will sodainly haue all the accidents of burning and swelling in the highest nature but first the skinne must be annointed with oyle of Lillies that so it beeing made more loose the Cupping-glasse may draw the stronger and more powerfully it ought to sticke to the part for the space of a quarter of an houre and to bee renewed and applied againe euerie three quarters of an houre for so at the length the venome shall bee the better drawne forth from anie noble part that is weake and the worke of suppuration or resolution whichsoeuer nature hath assaied will the better and sooner be