and_o alteration_n in_o a_o animal_n this_o helmont_n couch_v under_o the_o name_n of_o please_v the_o archaeus_n 3._o that_o it_o shall_v take_v away_o all_o grievance_n of_o the_o sensitive_a soul_n or_o archaeus_n because_o its_o grievance_n be_v the_o essential_a form_n of_o disease_n for_o even_o morbid_v matter_n unless_o it_o cause_v a_o grievance_n cause_v no_o more_o disease_n than_o it_o do_v in_o a_o dead_a carcase_n as_o helmont_n and_o common_a reason_n assure_v we_o therefore_o disease_n and_o grievance_n be_v only_o two_o word_n signify_v the_o same_o thing_n and_o nothing_o be_v capable_a of_o grievance_n in_o a_o animal_n as_o such_o but_o the_o sensitive_a soul_n 4._o it_o shall_v compose_v comfort_n enliven_v encourage_v and_o invigorate_v our_o sensitive_a soul_n and_o spirit_n as_o be_v the_o principle_n of_o motion_n in_o our_o animal_n nature_n in_o order_n to_o self_n preservation_n for_o nature_n or_o those_o active_a principle_n within_o we_o be_v the_o curer_n of_o disease_n and_o we_o physician_n only_a its_o minister_n to_o offer_v it_o good_a mean_n etc._n etc._n 5._o the_o principle_n of_o a_o panacea_fw-la shall_v be_v agreeable_a to_o the_o best_a noble_a most_o active_a and_o predominant_a principle_n of_o our_o body_n 6._o those_o principle_n in_o the_o panacea_fw-la shall_v be_v more_o vigorous_a than_o we_o to_o reduce_v they_o when_o deficient_a and_o exalt_v they_o when_o depress_v clog_v etc._n etc._n 7._o it_o shall_v be_v a_o general_a resolver_n of_o humour_n for_o which_o cause_n the_o liquor_n alcahe_o be_v so_o much_o extol_v for_o a_o panacea_fw-la hear_v what_o the_o great_a physician_n claudius_n de_fw-fr la_fw-fr courvee_n say_v uni_fw-la morbosae_fw-la &_o semper_fw-la preter_fw-la naturam_fw-la humorum_fw-la coagulationi_fw-la unique_fw-la eorundem_fw-la colliquationi_fw-la ovi_fw-fr perpetuo_fw-la intendit_fw-la natura_fw-la diligenter_n studeas_fw-la huius_fw-la adjuvandae_fw-la illius_fw-la corrigendae_fw-la modum_fw-la si_fw-la assecutus_fw-la fuâ—ris_fw-la habebis_fw-la in_o praxi_fw-la secretum_fw-la onmi_fw-la auro_fw-la potabili_fw-la omnique_fw-la antidoto_fw-la prestantius_fw-la denique_fw-la plus_fw-la poteris_fw-la in_o praxi_fw-la quam_fw-la si_fw-la cursus_fw-la astrorum_fw-la metallorum_fw-la vires_fw-la aut_fw-la totam_fw-la callueris_fw-la panaceam_fw-la 8._o it_o shall_v after_o such_o resolution_n of_o humour_n compose_v concentrate_v combine_v and_o unite_v the_o good_a principle_n 9_o it_o shall_v discuss_v the_o bad_a and_o useless_a part_n 10._o it_o shall_v open_v the_o pore_n to_o give_v they_o their_o exit_fw-la by_o that_o most_o universal_a natural_a plentiful_a kind_o and_o easy_a evacuation_n 11._o that_o after_o all_o it_o shall_v like_o the_o liquor_n alcahest_n remain_v very_o much_o unaltered_a in_o itself_o now_o whatsoever_o be_v endue_v with_o these_o eleven_o most_o noble_a qualification_n must_v be_v in_o the_o estimation_n of_o any_o rational_a physician_n or_o philosopher_n a_o glorious_a panacea_fw-la that_o be_v fit_v to_o take_v off_o the_o matter_n and_o form_n of_o all_o disease_n or_o grievance_n as_o far_o as_o it_o be_v in_o the_o power_n of_o a_o natural_a medicament_n or_o alterative_a so_o to_o do_v therefore_o let_v we_o see_v how_o the_o pure_a sal-volatile-oleosum_a of_o opium_n be_v furnish_v therewith_o 1._o it_o be_v so_o high_o agreeable_a and_o please_a to_o our_o most_o nice_a sensation_n at_o stomach_n which_o be_v give_v we_o for_o a_o touchstone_n watch_z and_o judge_n of_o what_o be_v agreeable_a and_o beneficial_a to_o our_o body_n that_o nothing_o in_o the_o whole_a world_n be_v so_o agreeable_a and_o please_a to_o it_o and_o therefore_o nothing_o be_v more_o agreeable_a and_o beneficial_a to_o our_o animal_n nature_n it_o will_v imply_v a_o contradiction_n that_o the_o stomach_n which_o be_v give_v we_o and_o according_o qualfy_v to_o make_v a_o true_a report_n of_o what_o be_v or_o be_v not_o agreeable_a and_o beneficial_a to_o we_o shall_v always_o though_o it_o may_v by_o accident_n possible_o give_v we_o a_o false_a report_n of_o the_o agreeableness_n of_o thing_n it_o will_v be_v more_o than_o profaneness_n to_o attribute_v such_o deceitful_a unkind_a and_o unwise_a contrivance_n to_o the_o infinite_o good_a and_o wise_a therefore_o the_o stomach_n do_v infallible_o testify_v and_o assure_v we_o that_o it_o be_v most_o agreeable_a to_o our_o nature_n see_v it_o be_v always_o so_o to_o it_o agreeableness_n and_o disagreeableness_n with_o which_o be_v appoint_v and_o ordain_v by_o god_n and_o nature_n to_o be_v the_o test_n and_o touchstone_n of_o what_o be_v agreeable_a or_o otherwise_o to_o our_o animal_n nature_n obj._n why_o then_o be_v so_o agreeable_a to_o the_o stomach_n shall_v it_o not_o create_v a_o appetite_n but_o rather_o lessen_v it_o ans._n though_o some_o may_v be_v so_o weak_a as_o to_o make_v such_o a_o objection_n because_o thing_n agreeable_a to_o the_o stomach_n be_v common_o repute_v to_o cause_v a_o appetite_n yet_o the_o matter_n due_o consider_v the_o case_n be_v quite_o contrary_a for_o appetite_n or_o hunger_n be_v a_o grievous_a sensation_n at_o stomach_n which_o can_v be_v expect_v from_o thing_n that_o gratify_v and_o please_v the_o stomach_n which_o be_v the_o adequate_a cure_n of_o a_o grievous_a sensation_n or_o hunger_n thus_o meat_n and_o drink_n as_o have_v be_v show_v cure_v a_o appetite_n grievous_a sensation_n or_o hunger_n thus_o wine_n and_o opium_n do_v by_o please_v the_o stomach_n cure_v a_o canine_a appetite_n etc._n etc._n therefore_o you_o may_v note_v by_o the_o by_o that_o all_o meat_n and_o drink_n that_o please_v the_o stomach_n and_o gratify_v its_o sense_n be_v real_o opiate_n in_o some_o degree_n cause_v good_a humour_n sleepiness_n etc._n etc._n appetite_n or_o hunger_n though_o it_o be_v a_o convenient_a call_n or_o intimation_n of_o want_n of_o supply_n and_o recruit_v be_v as_o such_o a_o consequent_a of_o defect_n and_o so_o unnatural_a though_o call_v natural_a because_o it_o be_v a_o thing_n that_o happen_v of_o course_n to_o direct_v we_o how_o to_o proportion_v thing_n to_o the_o exigence_n of_o nature_n of_o which_o there_o will_v be_v no_o need_n if_o we_o can_v otherwise_o proportion_v good_a and_o agreeable_a refection_n to_o our_o want_n thereof_o in_o short_a it_o be_v a_o disease_n which_o thing_n agreeable_a and_o please_a to_o the_o stomach_n as_o our_o panacea_fw-la must_v cure_v or_o else_o it_o will_v not_o be_v a_o panacea_fw-la and_o as_o be_v show_v nothing_o can_v be_v a_o more_o proper_a cure_n of_o grievance_n or_o displeasure_n than_o pleasure_n therefore_o what_o be_v agreeable_a to_o our_o stomach_n and_o consequent_o to_o our_o body_n must_v cure_v not_o cause_n appetite_n as_o meat_n and_o drink_n etc._n etc._n obj._n but_o it_o may_v be_v say_v that_o appetite_n argue_v a_o good_a digestion_n which_o be_v good_a for_o the_o body_n ans._n it_o do_v indeed_o argue_v a_o quick_a digestion_n and_o great_a expense_n of_o the_o recruit_n take_v in_o but_o still_o it_o be_v all_o bottom_v upon_o deficiency_n and_o digestion_n may_v be_v and_o be_v very_o often_o too_o quick_a as_o in_o the_o boulimia_fw-la or_o canine_a appetite_n nature_n delight_v in_o a_o gentle_a kind_a and_o gradual_a dissolution_n of_o the_o meat_n at_o stomach_n to_o which_o you_o will_v find_v by_o and_o by_o that_o opium_n very_o much_o conduce_v by_o its_o resolve_v quality_n 2._o nothing_o in_o nature_n be_v more_o please_v to_o the_o sensitive_a soul_n as_o appear_v by_o the_o whole_a series_n of_o our_o discourse_n and_o the_o explain_v all_o the_o phenomena_n or_o good_a effect_n of_o opium_n by_o that_o very_a pleasure_n of_o the_o sensitive_a soul_n therefore_o 3._o it_o as_o be_v manifest_o show_v do_v thereby_o take_v off_o all_o grievance_n which_o be_v the_o essential_a form_n of_o disease_n and_o the_o essential_a form_n of_o disease_n be_v take_v away_o which_o give_v they_o be_v and_o make_v they_o to_o be_v what_o they_o be_v according_a to_o the_o definition_n of_o a_o essential_a form_n the_o very_a be_v of_o disease_n must_v be_v take_v away_o therefore_o our_o sal-volatile-oleosum_a be_v a_o complete_a panacea_fw-la that_o take_v away_o the_o essence_n or_o be_v of_o disease_n in_o take_v away_o the_o grievance_n thereof_o here_o it_o may_v be_v say_v that_o the_o matter_n of_o the_o distemper_n remain_v and_o consequent_o a_o disposition_n to_o a_o relapse_n as_o soon_o as_o the_o sal-volatile-oleosum_a have_v end_v its_o operation_n but_o what_o need_v it_o end_n at_o all_o if_o you_o please_v it_o may_v be_v renew_v without_o danger_n for_o this_o be_v not_o as_o resinous_a opium_n till_o the_o matter_n be_v subdue_v thereby_o which_o it_o will_v also_o do_v as_o appear_v more_o manifest_o by_o the_o follow_a qualification_n for_o as_o have_v be_v show_v 4._o it_o compose_v comfort_n enlivens_fw-la encourage_v invigorate_n and_o cause_v a_o great_a euphory_n of_o the_o sensitive_a soul_n and_o spirit_n which_o be_v our_o natural_a active_a
watch_n and_o sentinel_n to_o discover_v and_o give_v notice_n of_o what_o be_v or_o be_v not_o good_a and_o agreeable_a to_o our_o animal_n nature_n that_o upon_o notice_n of_o what_o be_v good_a and_o agreeable_a pleasure_n comfort_n satisfaction_n etc._n etc._n be_v conceive_v otherwise_o displeasure_n discomfort_n and_o dissatisfaction_n what_o diminish_v or_o disable_v our_o spirit_n do_v we_o the_o great_a evil_n that_o can_v be_v and_o consequent_o sensation_n will_v according_a to_o its_o office_n give_v we_o such_o notice_n thereof_o as_o will_v cause_v displeasure_n etc._n etc._n otherwise_o these_o sentinel_n that_o god_n and_o nature_n have_v appoint_v for_o faithful_a notice_n will_v instead_o of_o trusty_a service_n which_o be_v the_o end_n they_o be_v make_v for_o deceive_v we_o and_o consequent_o do_v we_o mischief_n rather_o than_o good_a which_o be_v very_o profane_a if_o not_o blasphemous_a to_o assert_v as_o be_v high_o abusive_a of_o god_n goodness_n and_o wisdom_n to_o make_v thing_n in_o nature_n that_o will_v not_o only_o not_o answer_n but_o act_n quite_o contrary_a to_o their_o end_n it_o follow_v then_o that_o what_o cause_v such_o a_o mighty_a agreeable_a and_o pleasant_a sensation_n at_o stomach_n which_o be_v the_o great_a and_o most_o accurate_a judge_n of_o what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n can_v be_v destructive_a or_o disable_n of_o its_o spirit_n which_o be_v the_o most_o excellent_a and_o useful_a thing_n that_o belong_v thereto_o therefore_o opium_n which_o so_o mighty_o recommend_v itself_o to_o please_v and_o comfort_v the_o great_a judge_n that_o god_n have_v give_v to_o a_o sensible_a creature_n to_o discern_v what_o be_v good_a and_o evil_a for_o it_o can_v diminish_v or_o disable_v our_o spirit_n one_o may_v say_v what_o i_o dare_v not_o that_o the_o sensation_n at_o stomach_n may_v deceive_v we_o we_o may_v deceive_v ourselves_o and_o say_v so_o when_o that_o which_o please_v the_o stomach_n do_v not_o please_v our_o pervert_v imagination_n which_o make_v no_o argument_n let_v we_o therefore_o consider_v thing_n where_o there_o be_v no_o such_o vain_a imagination_n to_o contradict_v the_o good_a end_n of_o nature_n if_o the_o stomach_n and_o sense_n in_o a_o brute_n or_o mere_a animal_n which_o have_v no_o other_o mean_n to_o judge_n of_o what_o be_v good_a or_o evil_n for_o it_o shall_v not_o judge_v aright_o all_o the_o animal_n in_o the_o whole_a world_n will_v soon_o perish_v it_o be_v the_o vain_a opinion_n of_o man_n that_o persuade_v they_o that_o thing_n be_v cold_a when_o hot_a etc._n etc._n as_o in_o the_o case_n of_o opium_n when_o the_o sense_n true_o inform_v that_o it_o be_v hot_a if_o you_o will_v stand_v to_o your_o imagination_n and_o supposition_n for_o such_o all_o must_v be_v without_o the_o information_n of_o sense_n against_o the_o dictate_v of_o sensation_n you_o must_v inevitable_o err_v but_o one_o may_v say_v be_v the_o sense_n at_o stomach_n such_o a_o infallible_a guide_n always_o i_o believe_v it_o will_v be_v very_o hard_a to_o give_v many_o instance_n to_o the_o contrary_a and_o prove_v it_o well_o however_o if_o we_o do_v or_o may_v allow_v something_o of_o this_o kind_a to_o a_o pervert_v stomach_n at_o certain_a time_n to_o avoid_v a_o squabble_n about_o it_o it_o be_v never_o to_o be_v allow_v that_o all_o the_o stomach_n in_o the_o whole_a world_n shall_v be_v please_v with_o one_o and_o the_o same_o thing_n at_o all_o time_n and_o yet_o that_o this_o thing_n shall_v be_v so_o high_o pernicious_a to_o the_o animal_n as_o to_o diminish_v or_o disable_v its_o spirit_n then_o indeed_o it_o will_v follow_v that_o the_o most_o exquisite_a sense_n at_o stomach_n to_o discern_v what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n be_v absolute_o in_o vain_a which_o no_o man_n of_o reason_n that_o have_v any_o apprehension_n of_o the_o wisdom_n of_o god_n and_o nature_n can_v assert_v 3._o what_o be_v more_o notorious_a than_o that_o pleasure_n or_o be_v please_v raise_v and_o displeasure_n or_o be_v grieve_v depress_n the_o spirit_n be_v not_o all_o people_n pleasant_a gay_a and_o good_a humour_a brisk_a prompt_a etc._n etc._n when_o please_v do_v not_o man_n travel_v or_o labour_n with_o more_o ease_n in_o pleasant_a company_n etc._n etc._n but_o of_o these_o matter_n and_o the_o reason_n thereof_o more_o in_o the_o follow_a chapter_n 4._o how_o can_v opium_n that_o revive_v people_n when_o they_o be_v so_o dispirited_a that_o they_o be_v even_o almost_o die_v as_o when_o opium_n be_v want_v by_o such_o as_o use_v to_o take_v it_o in_o deliquiâ—ms_n and_o agony_n from_o paiâ—_n etc._n etc._n diminish_v or_o disable_v the_o spirit_n it_o be_v plain_a contradiction_n to_o say_v that_o it_o shall_v next_o to_o opium_n nothing_o revive_v people_n in_o such_o case_n better_o than_o wine_n and_o those_o thing_n that_o produce_v the_o same_o or_o like_a effect_n have_v like_o nature_n and_o who_o can_v say_v that_o wine_n that_o be_v make_v to_o glad_a the_o heart_n of_o man_n diminish_v or_o disable_v the_o spirit_n or_o that_o opium_n which_o produce_v all_o the_o sprightly_a enliven_a and_o encourage_v effect_n of_o generous_a wine_n in_o a_o more_o eminent_a manner_n than_o wine_n and_o in_o the_o 10000th_o part_n of_o its_o quantity_n and_o for_o a_o long_a time_n than_o wine_n cause_v they_o shall_v diminish_v or_o disable_v the_o spirit_n for_o instance_n wine_n and_o opium_n in_o a_o due_a quantity_n but_o opium_n in_o a_o far_o less_o quantity_n as_o be_v say_v cause_v a_o pleasant_a gay_a and_o good_a humour_n courage_n bravery_n magnanimity_n promptitude_n in_o business_n expediteness_n in_o management_n serenity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n fatigue_n etc._n etc._n both_o take_v away_o sadness_n grief_n melancholy_n fear_v depression_n of_o spirit_n etc._n etc._n both_o cause_n promptitude_n to_o venery_n sine_fw-la cerere_fw-la &_o baccho_fw-la friget_fw-la venus_n so_o wine_n and_o opium_n prevent_v and_o cure_v cold_a open_v the_o pore_n promote_v perspiration_n and_o sweat_n especial_o the_o follow_a morning_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v of_o opium_n and_o be_v notorious_a as_o to_o wine_n both_o cause_n sleep_n and_o take_v away_o the_o sense_n of_o pain_n and_o require_v a_o great_a dose_n than_o ordinary_a in_o proportion_n to_o the_o pain_n both_o take_v off_o shivering_n from_o fear_n cold_a or_o ague_n fit_n and_o cause_n mirth_n contentation_n and_o acquiescence_n dryness_n of_o the_o mouth_n thirst_v a_o sense_n of_o heat_n within_o we_o a_o dream_v condition_n pleasant_a dream_n if_o the_o quantity_n of_o wine_n be_v not_o grievous_a by_o its_o heat_n load_n etc._n etc._n nocturnal_a pollution_n and_o in_o some_o constitution_n both_o cause_n vigilancy_n but_o wine_n and_o opium_n cause_v that_o more_o rare_o than_o sleep_n both_o stop_n and_o cause_n vomit_v if_o they_o stay_v too_o long_o at_o stomach_n both_o moderate_a hunger_n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d and_o be_v good_a in_o a_o canine_a appetite_n both_o cause_n swim_v in_o the_o head_n etc._n etc._n so_o both_o in_o a_o excessive_a do_v do_v cause_n at_o first_o mirth_n and_o afterward_o a_o kind_n of_o drunken_a soper_n in_o some_o in_o other_o fury_n or_o madness_n sardonick_a laughter_n and_o weight_n at_o stomach_n vomit_n hiccough_n great_a heat_n at_o stomach_n debility_n and_o laxity_n of_o all_o part_n falter_v of_o the_o tongue_n scotomy_n and_o darkness_n of_o the_o eye_n vertigo_n laxity_n of_o the_o cornea_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la deadness_n of_o the_o eye_n to_o the_o view_n loss_n of_o memory_n venereal_a fury_n a_o high_a colour_n profuse_a sweat_v purge_v sometime_o alienation_n of_o the_o mind_n loss_n of_o memory_n and_o last_o great_a or_o lesser_a effect_n according_a to_o the_o do_v constitution_n etc._n etc._n so_o a_o long_a and_o lavish_a use_n of_o both_o cause_n a_o dull_a and_o moapish_a disposition_n dropsy_n fall_v of_o humour_n upon_o weaken_v part_n a_o sleepy_a disposition_n want_v of_o appetite_n weakness_n of_o digestion_n aptitude_n to_o sterility_n and_o abortion_n early_a decrepiteness_n stoop_v in_o the_o back_n tremble_v of_o the_o hand_n weakness_n of_o memory_n shortness_n of_o life_n difficulty_n and_o danger_n in_o sudden_o leave_v they_o off_o revive_v such_o as_o sink_v for_o want_n of_o either_o and_o supply_v the_o want_n of_o each_o other_o how_o can_v any_o have_v the_o face_n to_o say_v that_o a_o thing_n which_o agree_v so_o with_o generous_a wine_n in_o effect_n can_v be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n the_o mischief_n of_o excessive_a dose_n and_o lavish_a use_n of_o either_o be_v no_o argument_n against_o their_o inspirit_a nature_n if_o it_o be_v than_o wine_n be_v no_o cordial_n though_o make_v to_o glad_a the_o heart_n
principle_n of_o motion_n by_o which_o all_o ill_a matter_n be_v effective_o subdue_v when_o they_o act_v with_o alacrity_n and_o vigour_n they_o be_v the_o principal_a agent_n and_o we_o physician_n but_o as_o be_v say_v minister_n or_o as_o handmaid_n to_o offer_v or_o hand_n good_a matter_n medicament_n or_o instrument_n to_o those_o principal_a agent_n of_o nature_n and_o that_o this_o sal-volatile-oleosum_a of_o opium_n be_v the_o most_o proper_a matter_n or_o medicament_n we_o can_v put_v into_o nature_n hand_n so_o invigorate_v appear_v manifest_o in_o that_o 5._o its_o principle_n be_v the_o most_o agreeable_a to_o the_o best_a noble_a most_o active_a and_o predominant_a principle_n of_o our_o body_n as_o have_v be_v prove_v most_o evident_o plene_fw-la &_o plane_n nor_o be_v it_o only_o agreeable_a but_o 6._o more_o vigorous_a and_o powerful_a to_o actuate_v reduce_v alter_v or_o exalt_v our_o principle_n according_a to_o the_o direction_n of_o our_o invigorated_a nature_n or_o sensitive_a soul_n and_o spirit_n which_o have_v so_o convenient_a a_o instrument_n and_o high_o qualify_v a_o matter_n will_v soon_o alter_v the_o perverse_a renew_v the_o decay_a acuate_v the_o dull_a and_o elevate_v the_o depress_v effete_a and_o pall_a humour_n of_o our_o body_n especial_o see_v 7._o that_o the_o sal-volatile-oleosum_a of_o opium_n be_v so_o agreeable_a and_o powerful_a must_v be_v the_o great_a resolver_n of_o humour_n that_o can_v be_v imagine_v for_o all_o resolution_n be_v by_o a_o agreement_n of_o particle_n which_o make_v they_o easy_o miscible_a insinuate_v into_o and_o penetrate_v each_o other_o especial_o if_o one_o be_v somewhat_o more_o vigorous_a and_o penetrate_a than_o the_o other_o as_o the_o sal-volatile-oleosum_a have_v be_v plain_o prove_v to_o be_v thus_o it_o be_v that_o all_o menstruum_n do_v so_o resolve_v thing_n of_o their_o own_o nature_n and_o so_o purify_v and_o cleanse_v they_o by_o take_v to_o themselves_o what_o be_v mere_o and_o pure_o of_o the_o same_o nature_n and_o reject_v or_o let_v go_v their_o hold_n of_o what_o be_v otherwise_o where_o it_o be_v worth_a note_n how_o upon_o the_o account_n of_o the_o intimate_a combination_n and_o union_n of_o the_o volatile_a salt_n and_o oily_a part_n in_o our_o panacea_fw-la it_o be_v dissolvable_a in_o all_o menstruum_n and_o consequent_o a_o universal_a resolvent_fw-la of_o all_o the_o humour_n of_o our_o body_n which_o its_o external_a resolve_v of_o all_o humour_n and_o tumor_n do_v also_o prove_v now_o if_o it_o be_v such_o a_o resolver_n of_o which_o there_o be_v no_o place_n to_o doubt_v then_o as_o claudius_n de_fw-fr la_fw-fr courvee_n say_v it_o must_v excel_v all_o thing_n in_o alter_v and_o reduce_v all_o the_o humour_n of_o our_o body_n to_o a_o good_a and_o agreeable_a condition_n nor_o do_v it_o only_o thus_o resolve_v they_o and_o thereby_o separate_v as_o be_v say_v the_o good_a from_o the_o bad_a but_z 8._o when_o it_o have_v so_o do_v it_o by_o the_o amicable_a agreeableness_n of_o its_o sal-volatile-oleosum_a compose_v faculty_n strict_a combination_n of_o its_o principle_n join_v to_o concentrate_n congregate_n and_o as_o it_o be_v cement_v the_o best_a and_o most_o agreeable_a into_o a_o close_a union_n and_o firm_a texture_n by_o as_o be_v say_v the_o direction_n of_o invigorated_a nature_n which_o be_v of_o itself_o the_o good_a be_v once_o separate_v from_o the_o bad_a high_o sufficient_a without_o any_o other_o help_v to_o unite_v part_n so_o agreeable_a and_o of_o themselves_o incline_v to_o unite_v and_o combine_v though_o all_o tho_o part_n of_o opium_n like_o those_o of_o the_o great_a dissolvent_a be_v go_v and_o when_o that_o be_v do_v 9_o the_o high_a discussive_a quality_n of_o the_o sal-volatile-oleosum_a must_v be_v very_o effectual_a for_o the_o difflation_n and_o discussion_n of_o the_o sever_a effete_a particle_n which_o must_v be_v high_o assist_v and_o improve_v by_o the_o brisk_a and_o cheerful_a motion_n of_o nature_n viz._n the_o sensitive_a soul_n and_o spirit_n so_o as_o be_v aforesaid_a invigorate_v nor_o be_v this_o all_o but_o to_o complete_a and_o perfect_a the_o operation_n 10._o it_o lay_v open_a all_o the_o pore_n of_o the_o body_n as_o have_v be_v demonstrate_v 〈◊〉_d they_o out_o and_o give_v the_o ill_a particle_n their_o â—inal_n exit_fw-la by_o the_o most_o natural_a and_o plentiful_a way_n of_o evacuation_n leave_v the_o body_n free_a from_o all_o miasm_n and_o impurity_n 11._o i_o have_v sufficient_o show_v how_o unalterable_a it_o be_v in_o itself_o chap._n 15._o so_o that_o like_o the_o liquor_n alcahest_fw-mi it_o be_v not_o make_v to_o be_v subdue_v but_o to_o subdue_v and_o resolve_v humour_n now_o what_o can_v be_v require_v more_o in_o a_o medicament_n and_o how_o can_v the_o sensitive_a soul_n and_o spirit_n or_o nature_n so_o invigorate_v and_o endue_v with_o all_o euphory_n and_o cheerfulness_n by_o this_o glorious_a medicament_n who_o principle_n be_v not_o only_o agreeable_a to_o our_o noble_a one_o but_o more_o powerful_a and_o intimate_o combine_v so_o resolve_v of_o humour_n ready_a to_o unite_v the_o good_a and_o to_o discuss_v the_o bad_a and_o carry_v they_o off_o by_o the_o pore_n ever_o fail_v be_v due_o administer_v of_o good_a effect_n in_o alter_v all_o the_o humour_n of_o our_o body_n hypocrates_n in_o his_o book_n de_fw-fr nature_n hominis_fw-la state_n the_o cause_n of_o disease_n to_o be_v a_o disgregation_n of_o humour_n by_o which_o he_o seem_v to_o imply_v that_o the_o power_n of_o congregate_a and_o concentrate_v of_o humour_n be_v sufficient_a to_o accomplish_v a_o panacea_fw-la which_o be_v but_o one_o single_a qualification_n in_o eleven_o of_o our_o sal-volatile-oleosum_a though_o this_o alone_a as_o be_v experience_v even_o in_o common_a preparation_n of_o opium_n suffice_v very_o often_o to_o cure_v disease_n by_o compose_v commotion_n as_o in_o diary_n fever_n from_o perturbation_n etc._n etc._n thus_o the_o bitter_a and_o firm_a texture_v cortex_fw-la as_o i_o have_v show_v in_o my_o book_n de_fw-fr febribus_fw-la intermittentibus_fw-la take_v off_o ague_n fit_v by_o re-combining_a the_o segregated_a humour_n with_o the_o blood_n which_o it_o sudden_o do_v leave_v a_o disposition_n in_o the_o blood_n when_o ever_o it_o meet_v with_o a_o segregate_a cause_n as_o purge_v violent_a motion_n insolation_n intemperate_a drink_v etc._n etc._n to_o a_o relapse_n by_o a_o second_o separation_n of_o the_o morbid_v matter_n from_o it_o as_o you_o have_v it_o more_o at_o large_a in_o my_o say_a book_n p._n 166_o 167_o etc._n etc._n 242_o 243_o etc._n etc._n where_o you_o may_v see_v how_o opiate_n conduce_v very_o much_o to_o a_o speedy_a cure_n by_o the_o cortex_fw-la by_o compose_v etc._n etc._n martianus_n say_v coâ—m_fw-la de_fw-fr locis_fw-la in_o homine_fw-la p._n 76._o opium_n sist_z it_o &_o prohibet_fw-la humorum_fw-la disgregationem_fw-la that_o be_v opium_n hinder_v disgregation_n of_o humour_n now_o you_o may_v perceive_v the_o true_a qualification_n of_o a_o sal-volatile-oleosum_a so_o much_o seek_v for_o by_o the_o learned_a as_o a_o panacea_fw-la and_o how_o far_o the_o common_a one_o that_o be_v sell_v in_o the_o apothecary_n shop_n be_v from_o be_v such_o silvius_n indeed_o have_v a_o excellent_a one_o with_o which_o he_o do_v many_o and_o great_a cure_n which_o be_v consider_v have_v he_o not_o confess_v his_o ignorance_n of_o the_o cause_n of_o the_o effect_n of_o opium_n and_o the_o narrative_a he_o make_v of_o its_o virtue_n and_o performance_n in_o his_o preface_n to_o the_o first_o book_n of_o his_o praxis_fw-la and_o that_o he_o delight_v so_o much_o in_o the_o use_n of_o opium_n even_o when_o he_o be_v young_a that_o he_o be_v call_v by_o the_o name_n of_o doctor_n opiatus_fw-la and_o that_o he_o declare_v no_o oil_n be_v add_v in_o its_o preparation_n and_o that_o it_o be_v intimate_v that_o the_o oil_n and_o volatile_a part_n be_v strict_o combine_v will_v have_v make_v i_o suspect_n that_o it_o be_v the_o sal-volatile-oleosum_a of_o opium_n that_o he_o use_v which_o if_o it_o be_v not_o i_o dare_v be_v confident_a that_o notwithstanding_o all_o its_o excellency_n it_o be_v not_o as_o good_a i_o be_o very_a well_o satisfy_v that_o a_o true_a and_o consummate_v sal-volatile-oleosum_a be_v not_o to_o be_v make_v bare_o by_o art_n enquirer_n may_v have_v better_a success_n if_o they_o seek_v it_o among_o the_o natural_a tribe_n of_o bitter_a plant_n that_o be_v agreeable_a to_o the_o stomach_n which_o have_v all_o in_o they_o a_o sal-volatile-oleosum_a but_o how_o to_o pick_v and_o cull_v be_v i_o think_v best_o see_v by_o the_o requisite_a qualification_n of_o a_o panacea_fw-la that_o i_o have_v state_v there_o have_v be_v many_o in_o who_o hand_n bitter_a thing_n have_v be_v as_o a_o panacea_fw-la one_o in_o germany_n cure_v most_o disease_n with_o wild_a sage_n some_o have_v do_v great_a thing_n with_o agrimony_n other_o
nothing_o more_o sure_a than_o that_o it_o have_v such_o a_o effect_n if_o the_o do_v be_v large_a enough_o and_o that_o most_o of_o the_o eastern_a nation_n use_v it_o for_o that_o end_n with_o infallible_a effect_n iii_o the_o time_n shall_v be_v 5_o or_o 6_o hour_n before_o the_o effect_n be_v expect_v or_o at_o bedtime_n to_o cause_v its_o effect_n towards_o the_o morning_n particular_o in_o the_o case_n of_o exciting_a to_o venery_n iv_o the_o regimen_n as_o to_o diet_n it_o must_v be_v nourish_v warm_a comfort_a and_o titillate_v with_o realish_v and_o high_a sauce_n oyster_n anchovy_n caviar_n cockle_n ketchup_o mango_n garlic_n onion_n leek_n bear_v garlic_n rocket_n sives_z shelot_n ginger_n aromatics_n roâ—ts_n of_o satyrion_n feaverfew_n goatsbeard_n silver-weed_n skirret_n parsnip_n and_o artichoke_n the_o use_n of_o ambergrise_n musk_n and_o civet_n be_v commend_v but_o good_a stomach-wine_n and_o thâ—_n like_a be_v certain_o of_o use_n sine_fw-la baccho_fw-la friget_fw-la venus_n but_o it_o be_v certain_a that_o camphire_n and_o sulphureous_a thing_n unferment_v as_o oil_n rosin_n and_o fat_a thing_n oppose_v titillation_n as_o do_v also_o slimy_a mucilaginous_a and_o cool_a thing_n chap._n thirty-nine_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o cause_n watch_v i_o have_v show_v how_o opiate_n cause_v watch_v in_o some_o person_n by_o reason_n of_o the_o over-agitating_a and_o actuate_a the_o spirit_n and_o titillate_v by_o its_o volatile_a salt_n yet_o do_v they_o by_o cause_v pleasure_n and_o relaxation_n support_v the_o spirit_n while_o the_o extraordinary_a ovation_n of_o they_o hinder_v sleep_n therefore_o it_o be_v of_o use_n to_o such_o as_o it_o cause_v watch_v to_o when_o it_o be_v requisite_a for_o they_o to_o watch_v about_o any_o business_n labour_n journey_n etc._n etc._n i._o the_o form_n may_v be_v either_o solid_a or_o liquid_a ii_o the_o do_v moderate_a iii_o the_o vehicle_n shall_v be_v acid_n or_o other_o liquid_n with_o volatile_a salt_n iv_o the_o time_n may_v be_v at_o any_o hour_n when_o want_v v._o the_o regimen_n quite_o contrary_a to_o that_o of_o sleep_n and_o relaxation_n viz._n to_o use_v voluntary_a motion_n etc._n etc._n chap._n xl._n of_o the_o alterative_a use_n of_o the_o panacea_fw-la of_o opium_n you_o see_v the_o mighty_a extent_n and_o general_n use_v of_o the_o panacea_fw-la of_o opium_n as_o a_o pleaser_n of_o sensation_n which_o take_v up_o the_o nine_o last_o chapter_n to_o mention_v the_o head_n of_o its_o performance_n without_o descend_v into_o all_o particular_n because_o their_o number_n be_v indefinite_a how_o universal_a then_o must_v its_o use_n be_v when_o we_o add_v thereto_o its_o effect_n as_o a_o consummate_a alterative_a which_o 1._o invigorates_n nature_n by_o comfort_v the_o sublimest_n principles_n thereof_o viz._n the_o sensitive_a soul_n and_o spirit_n that_o be_v the_o original_a of_o all_o motion_n and_o action_n 2._o furnish_v they_o with_o a_o indefatigable_a euphory_n in_o the_o great_a business_n of_o our_o preservation_n 3._o put_v the_o best_a mean_n into_o the_o hand_n of_o invigorated_a nature_n for_o that_o end_n that_o be_v most_o agreeable_a principle_n even_o more_o powerful_a and_o of_o a_o great_a energy_n than_o our_o own_o which_o must_v as_o agreeable_a and_o exalt_a menstruum_n do_v resolve_v all_o humour_n congregate_a the_o good_a and_o homogeneous_a and_o separate_v the_o effete_a and_o heterogeneous_a part_n which_o it_o 4._o discuss_n and_o dissipate_v by_o its_o brisk_a and_o active_a volatile_a salt_n and_o at_o last_o 5._o convey_v out_o of_o the_o body_n by_o a_o liberal_a perspiration_n the_o most_o natural_a universal_a and_o copious_a way_n of_o evacuation_n all_o which_o be_v consider_v it_o be_v i_o think_v manifest_a that_o it_o must_v excel_v all_o other_o panaceas_fw-la 1._o because_o it_o take_v away_o the_o grievance_n or_o form_n of_o disease_n upon_o the_o very_a first_o administration_n thereof_o whereas_o other_o medicament_n do_v that_o but_o gradual_o as_o they_o alter_v or_o subdue_v the_o matter_n 2._o because_o it_o high_o comfort_v nature_n or_o the_o sensitive_a soul_n and_o spirit_n from_o the_o very_a commencement_n of_o the_o cure_n and_o through_o the_o whole_a process_n thereof_o if_o due_o repeat_v which_o other_o medicament_n do_v only_o by_o insensible_a degree_n as_o they_o gain_v upon_o the_o disease_n 3._o because_o it_o procure_v sleep_n the_o sweet_a and_o chief_a refreshment_n of_o and_o first_o cure_n in_o nature_n so_o that_o i_o can_v see_v what_o can_v be_v desire_v in_o a_o medicament_n that_o it_o be_v not_o accomplish_v with_o whereas_o other_o panaceas_fw-la be_v deficient_a or_o at_o least_o come_v very_o short_a of_o we_o in_o these_o extraordinary_a qualification_n which_o seem_v to_o make_v it_o absolute_o complete_a and_o consummate_a 4._o because_o it_o from_o the_o very_a first_o compose_v all_o perturbation_n and_o enormous_a motion_n of_o the_o sensitive_a soul_n or_o â—_z which_o helmont_n attribute_n to_o the_o archaeus_n place_v all_o disease_n therein_o and_o therefore_o say_v ort._n imag._n mâ—rb_n sect._n 12._o universal_a quoddam_fw-la arcanum_fw-la consopotivum_fw-la &_o sedativum_fw-la archaei_n est_fw-la adhibendum_fw-la that_o be_v a_o universal_a remedy_n that_o appease_v the_o archaeus_n shall_v be_v use_v and_o what_o appease_v or_o compose_v it_o more_o than_o or_o as_o much_o as_o opiate_n therefore_o i_o can_v wonder_v that_o paracelsus_n shall_v declare_v that_o it_o serve_v his_o purpose_n when_o all_o his_o arcanas_fw-la sail_v or_o that_o helmont_n shall_v be_v in_o a_o rapture_n upon_o the_o apprehension_n of_o the_o excellency_n of_o opium_n if_o the_o noxious_a quality_n be_v separate_v from_o it_o though_o he_o have_v a_o very_a wrong_a notion_n of_o its_o operation_n as_o appear_v potest_fw-la medicam_fw-la sect._n 4._o where_o he_o say_v that_o opium_n archaeum_n abigit_fw-la &_o fugat_fw-la that_o be_v opium_n chase_v and_o put_v the_o archaeus_n to_o flight_n which_o on_o the_o contrary_a it_o high_o please_v and_o comfort_n it_o be_v endless_a and_o a_o kind_a of_o impertinence_n to_o descend_v into_o particular_n in_o the_o use_n of_o a_o panacea_fw-la therefore_o have_v show_v how_o it_o operate_v by_o invigorate_n nature_n cause_v euphory_n ease_n sleep_v resolve_v all_o humour_n as_o a_o general_a menstruum_fw-la or_o alkahe_a congregate_a the_o good_a separate_a discuss_v and_o carry_v off_o the_o bad_a particle_n etc._n etc._n it_o remain_v only_o that_o i_o show_v you_o how_o to_o use_v it_o as_o to_o form_n do_v etc._n etc._n leave_v the_o administration_n thereof_o in_o particular_a case_n to_o physician_n therein_o concern_v i._o the_o form_n that_o i_o main_o approve_v of_o to_o alter_v be_v the_o liquid_a because_o the_o solid_a be_v in_o some_o measure_n though_o not_o much_o impair_v by_o the_o evaporation_n to_o the_o due_a consistence_n and_o do_v not_o consist_v of_o the_o fine_a part_n as_o the_o liquid_a do_v ii_o the_o dose_n may_v be_v at_o first_o about_o 20_o drop_n add_v a_o drop_n to_o every_o do_v till_o the_o distemper_n be_v in_o good_a measure_n abate_v then_o let_v the_o same_o number_n of_o drop_n be_v continue_v till_o the_o person_n be_v well_o and_o afterward_o abate_v by_o a_o drop_v every_o day_n till_o you_o come_v to_o ten_o or_o less_o or_o to_o such_o a_o inconsiderable_a do_v that_o you_o can_v find_v no_o effect_n at_o all_o note_v that_o though_o i_o be_o cautious_a in_o the_o dose_v till_o trusty_a experience_n give_v more_o assurance_n yet_o do_v i_o believe_v that_o no_o inconvenience_n will_v be_v find_v by_o far_o great_a dose_n if_o by_o any_o unless_o very_o excessive_a as_o 1_o or_o 2_o gallon_n of_o wine_n be_v in_o respéct_n of_o a_o pint_n which_o in_o such_o dose_n may_v be_v and_o be_v injurious_a such_o as_o have_v pain_n to_o be_v take_v off_o must_v use_v it_o as_o be_v direct_v in_o the_o chapter_n of_o its_o use_n to_o take_v away_o pain_n gradual_o increase_a so_o as_o to_o keep_v it_o off_o and_o when_o the_o cure_n be_v in_o great_a measure_n perform_v must_v continue_v and_o decrease_v as_o be_v aforesaid_a the_o like_a be_v to_o be_v say_v as_o to_o flux_n etc._n etc._n iii_o the_o vehicle_n may_v be_v in_o general_a plain_a water_n or_o rather_o alter_v and_o make_v bitter_a by_o a_o infusion_n of_o the_o ingredient_n of_o the_o bitter_a decoction_n or_o agrimony_n wood-sage_a bean_n trefoil_n or_o the_o like_a good_a bitter_a thing_n that_o be_v know_v by_o experience_n to_o cause_v a_o good_a digestion_n in_o particular_a case_n the_o vehicle_n may_v be_v appropriate_v to_o the_o disease_n yet_o always_o so_o order_v it_o that_o it_o may_v be_v stomachical_a iv_o the_o time_n shall_v general_o be_v in_o the_o morning_n unless_o sleep_v at_o night_n be_v to_o be_v procure_v thereby_o if_o so_o you_o must_v order_v thing_n as_o in_o the_o
a_o very_o long_o and_o lavish_a use_n thereof_o the_o inconvenience_n of_o leave_v off_o the_o use_n of_o opium_n do_v bear_v a_o certain_a proportion_n to_o the_o time_n and_o quantity_n that_o it_o have_v be_v use_v in_o 1._o note_v that_o the_o turk_n do_v drink_v some_o water_n always_o after_o the_o take_n of_o opium_n as_o be_v the_o best_a menstruum_fw-la to_o dissolve_v it_o 2._o note_v that_o it_o be_v usual_a with_o they_o to_o take_v a_o drachm_n in_o the_o morning_n and_o so_o much_o in_o the_o afternoon_n and_o so_o may_v we_o as_o well_o as_o they_o if_o use_v to_o it_o and_o it_o be_v a_o very_a silly_a say_n that_o you_o will_v find_v in_o author_n that_o they_o be_v better_a able_a to_o bear_v it_o because_o of_o the_o climate_n etc._n etc._n whereas_o the_o more_o northern_a person_n be_v better_a able_a to_o take_v it_o than_o the_o southern_a as_o will_v hereafter_o appear_v most_o plain_o i_o be_o tell_v of_o one_o near_o banbury_n that_o take_v two_o ounce_n a_o day_n 3._o note_v that_o among_o the_o effect_n of_o opium_n may_v be_v observe_v many_o seem_a contradiction_n yet_o be_v there_o nothing_o more_o certain_a than_o the_o several_a different_a matter_n of_o fact_n which_o no_o doubt_n have_v be_v a_o great_a cause_n to_o puzzle_v the_o world_n about_o it_o and_o to_o run_v man_n into_o strange_a absurdity_n concern_v its_o operation_n and_o all_o to_o deviate_v so_o far_o from_o the_o truth_n that_o nothing_o in_o nature_n can_v be_v far_o unless_o you_o will_v say_v that_o heat_n cool_v or_o what_o please_v the_o sensitive_a soul_n be_v at_o the_o same_o time_n abhor_v by_o it_o now_o because_o these_o seem_a contradiction_n in_o the_o effect_n of_o opium_n be_v the_o great_a rub_n to_o be_v meet_v with_o and_o that_o the_o reader_n may_v take_v the_o better_a estimate_n of_o the_o undertake_n and_o my_o explication_n of_o its_o effect_n when_o i_o come_v to_o it_o i_o shall_v not_o fear_v to_o enumerate_v they_o distinct_o though_o they_o will_v make_v the_o strange_a catalogue_n of_o riddle_n that_o ever_o be_v see_v trust_v in_o he_o that_o create_v this_o wonderful_a medicament_n that_o he_o will_v enable_v i_o to_o explain_v all_o its_o effect_n the_o seem_a contradiction_n in_o the_o effect_n of_o opium_n 1._o it_o cause_v sleep_v and_o watch_v 2._o it_o cause_n and_o prevent_v sweat_n 3._o it_o relax_n and_o stop_v looseness_n 4._o it_o stop_v flux_n and_o cause_n that_o of_o sweat_n etc._n etc._n 5._o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v by_o that_o sense_n to_o venery_n 6._o it_o cause_v stupidity_n and_o promptitude_n in_o business_n cloudiness_n and_o serenity_n of_o mind_n 7._o it_o excite_v the_o spirit_n and_o quiet_v they_o 8._o it_o be_v very_o hot_a yet_o cool_v in_o fever_n 9_o it_o be_v hot_a and_o bitter_a yet_o lessen_v appetite_n even_o in_o cold_a stomach_n 10._o it_o stop_v and_o promote_v urine_n 11._o it_o relax_n and_o weaken_v yet_o enable_v we_o to_o undergo_v labour_n journey_n etc._n etc._n 12._o it_o cause_n and_o prevent_v abortion_n 13._o it_o stop_v vomit_v above_o all_o thing_n yet_o cause_n most_o violent_a tedious_a and_o dangerous_a vomit_n 14._o it_o stop_v purge_v in_o a_o most_o eminent_a manner_n yet_o sometime_o cause_v it_o 15._o it_o be_v very_o acrimonious_a yet_o as_o all_o say_v obtund_v acrimony_n however_o it_o allay_v pain_n proceed_v from_o acrimony_n 16._o it_o cause_v a_o furious_a madness_n yet_o compose_v the_o spirit_n above_o all_o thing_n 17._o it_o cause_v 〈◊〉_d yet_o sometime_o cure_v they_o as_o willis_n say_v 18._o it_o cause_v palsy_n yet_o have_v i_o know_v it_o to_o cure_v a_o palsy_n 19_o it_o cause_v dryness_n in_o the_o mouth_n yet_o take_v off_o thirst_n in_o fever_n 20._o it_o cure_v and_o cause_v a_o hiccough_n 21._o it_o stanche_n blood_n yet_o cause_v the_o blood_n to_o come_v outward_a as_o appear_v by_o the_o efflorescence_n or_o redness_n of_o the_o skin_n that_o it_o cause_n yet_o move_v the_o menses_fw-la and_o lochia_n 22._o we_o have_v many_o instance_n of_o it_o promote_a and_o hinder_v critical_a motion_n 23._o it_o raise_v very_o weak_a people_n when_o nothing_o beside_o will_v do_v it_o yet_o it_o kill_v other_o weak_a people_n 24._o it_o cause_n and_o cure_n convulsion_n 25._o it_o cause_v relaxation_n and_o contraction_n of_o the_o same_o part_n 26._o it_o relax_n yet_o cause_v rigidity_n tension_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n thus_o have_v i_o fair_o and_o faithful_o lay_v the_o whole_a onus_fw-la of_o the_o operation_n effect_n and_o contradictory_n phenomena_n of_o opium_n upon_o my_o shoulder_n however_o i_o come_v off_o and_o clear_v myself_o of_o the_o intricacy_n maze_n and_o cross_a effect_n thereof_o by_o explain_v they_o which_o none_o upon_o the_o view_n thereof_o will_v think_v possible_a and_o none_o before_o i_o dare_v as_o much_o as_o enumerate_v for_o that_o end_n chap._n vii_o the_o author_n contrive_v a_o compendious_a way_n of_o examine_v all_o opinion_n concern_v the_o operation_n of_o opium_n have_v without_o any_o sly_a or_o sordid_a evasion_n or_o considerable_a omission_n which_o have_v be_v the_o perfidious_a course_n of_o author_n in_o this_o case_n full_o and_o true_o enumerate_v the_o sensible_a and_o certain_a effect_n of_o opium_n in_o humane_a body_n and_o thereby_o empanneled_a a_o just_a jury_n for_o the_o trial_n of_o hypothesise_n which_o must_v be_v judge_v by_o the_o effect_n or_o phenomena_n of_o opium_n i_o will_v now_o proceed_v to_o their_o examination_n but_o because_o it_o will_v be_v endless_a to_o take_v every_o one_o particular_o into_o consideration_n i_o will_v use_v their_o stratagem_n who_o blow_v up_o foundation_n to_o save_v the_o tedious_a peck_v at_o all_o the_o part_n of_o the_o superstructure_n which_o in_o this_o case_n will_v require_v a_o age_n and_o take_v up_o all_o my_o time_n in_o demolish_n they_o which_o may_v be_v better_o employ_v in_o erect_v something_o that_o may_v be_v useful_a i_o have_v consider_v and_o find_v that_o the_o foundation_n in_o which_o all_o author_n both_o ancient_a and_o modern_a agree_v and_o whereupon_o they_o have_v hitherto_o endeavour_v to_o build_v look_v upon_o it_o as_o firm_a and_o warrantable_a in_o all_o age_n be_v this_o viz._n that_o opium_n operate_v by_o diminish_v or_o disable_n the_o spirit_n mean_v the_o animal_n spirit_n the_o ancient_n affirm_v that_o it_o do_v so_o by_o a_o extreme_a cold_a quality_n etc._n etc._n and_o the_o modern_n who_o observe_v it_o to_o act_n while_o it_o be_v at_o stomach_n by_o affect_v the_o brain_n nerve_n animal_n spirit_n etc._n etc._n and_o conclude_v no_o action_n be_v perform_v without_o contact_n infer_v and_o agree_v because_o no_o visible_a passage_n can_v be_v find_v from_o the_o stomach_n to_o the_o head_n that_o it_o must_v of_o absolute_a necessity_n act_v by_o fume_n vapour_n auras_fw-la or_o effluvium_n send_v up_o out_o of_o the_o stomach_n to_o the_o brain_n nerve_n etc._n etc._n so_o that_o all_o the_o remain_a question_n among_o the_o modern_n be_v which_o way_n those_o fume_n or_o vapour_n do_v the_o feat_n all_o allow_v the_o fume_n do_v it_o one_o say_v that_o they_o stuff_v the_o pore_n of_o the_o brain_n and_o so_o hinder_v the_o generation_n of_o animal_n spirit_n a_o second_o that_o they_o constringed_a and_o close_v the_o pore_n together_o thereby_o hinder_v the_o say_a generation_n a_o three_o that_o they_o fix_v and_o coagulate_v the_o animal_n spirit_n as_o wedelius_n and_o other_o a_o four_o that_o they_o cloud_v the_o animal_n spirit_n a_o five_o that_o they_o act_v as_o a_o poison_n as_o willis_n and_o many_o other_o a_o six_o that_o they_o clog_v the_o animal_n spirit_n by_o adhere_v to_o they_o etc._n etc._n not_o know_v nor_o i_o think_v care_v what_o they_o say_v so_o they_o humour_a their_o own_o imagination_n and_o hypothesise_n though_o utter_o incapable_a of_o solve_v the_o effect_n of_o opium_n especial_o be_v most_o constant_a proper_a and_o genuine_a effect_n for_o how_o can_v a_o cold_a quality_n which_o opium_n never_o have_v cause_v a_o gay_a and_o brisk_a humour_n bravery_n magnanimity_n euphory_n in_o labour_n promptitude_n to_o venus_n etc._n etc._n and_o how_o can_v cloud_n of_o vapour_n hinder_v the_o generation_n of_o animal_n spirit_n by_o stuff_v or_o constr_v the_o pore_n of_o the_o brain_n poison_v fix_v coagulate_v clog_a or_o cloud_v the_o animal_n spirit_n cause_v a_o fine_a ovation_n thereof_o a_o gay_a brave_a courageous_a and_o magnanimous_a disposition_n euphory_n promptitude_n to_o venery_n serenity_n expediteness_n in_o management_n etc._n etc._n which_o be_v as_o have_v be_v say_v the_o constant_a and_o proper_a effect_n of_o opium_n nor_o indeed_o be_v any_o of_o those_o author_n so_o foolhardy_a as_o to_o attempt_v it_o
which_o give_v the_o occasion_n as_o you_o may_v remember_v to_o the_o hypothesis_n of_o its_o operate_n by_o fume_n rise_v out_o of_o the_o stomach_n because_o they_o can_v not_o think_v of_o any_o other_o mean_v by_o which_o it_o may_v affect_v the_o head_n brain_n animal_n spirit_n nerve_n etc._n etc._n while_o it_o be_v at_o stomach_n but_o by_o the_o way_n of_o fume_n or_o vapour_n it_o be_v therefore_o past_a all_o doubt_n that_o opium_n produce_v its_o common_a effect_n while_o it_o be_v at_o stomach_n and_o before_o it_o arrive_v at_o the_o blood_n and_o therefore_o do_v not_o operate_v as_o a_o alterative_a thereof_o second_o because_o a_o grain_n of_o opium_n which_o operate_v very_o remarkable_o bear_v as_o etmuller_n well_o observe_v so_o small_a a_o proportion_n to_o the_o blood_n that_o it_o can_v produce_v such_o great_a and_o notable_a effect_n as_o a_o alterative_a thereof_o for_o a_o grain_n of_o opium_n to_o 20_o pound_n of_o blood_n which_o a_o ordinary_a man_n have_v in_o his_o body_n be_v but_o as_o 1_o to_o 115200_o or_o if_o 16_o oucne_n be_v allow_v to_o the_o pound_n as_o 1_o to_o 153600._o but_o it_o be_v no_o wonder_n if_o a_o grain_n shall_v affect_v the_o membrane_n at_o stomach_n since_o the_o 1000_o part_n of_o a_o grain_n of_o the_o vomitory_n particle_n of_o crocus_n metallorum_fw-la or_o regulus_n of_o antimony_n do_v affect_v it_o so_o eminent_o as_o many_o other_o thing_n will_v in_o a_o very_a small_a quantity_n whereas_o the_o alter_n of_o the_o blood_n to_o any_o observable_a degree_n require_v the_o use_n of_o alterative_n in_o great_a quantity_n for_o several_a week_n which_o confirm_v the_o former_a conclusion_n that_o opium_n do_v not_o operate_v as_o a_o alterative_a as_o to_o its_o common_a and_o usual_a effect_n ii_o opium_n do_v not_o operate_v by_o grievous_a sensation_n or_o irritation_n as_o vomit_n purger_n errhine_n salivator_n or_o apophlegmatizer_n etc._n etc._n do_v first_o because_o it_o manifest_o cause_v a_o very_a agreeable_a pleasant_a and_o even_o charm_a sensation_n second_o because_o it_o take_v away_o grievous_a sensation_n or_o pain_n thereby_o stop_v vomit_v purge_v and_o all_o other-effect_n of_o grievous_a sensation_n by_o acrimony_n etc._n etc._n as_o for_o the_o vomit_v that_o opium_n sometime_o cause_n it_o be_v only_o as_o shall_v be_v show_v by_o its_o resinous_n part_n stick_v to_o the_o coat_n of_o the_o stomach_n which_o be_v separate_v from_o it_o opium_n have_v no_o such_o effect_n though_o all_o its_o good_a effect_n remain_v so_o its_o purge_v which_o happen_v most_o rare_o and_o only_o when_o a_o great_a quantity_n be_v give_v to_o man_n of_o strong_a digestion_n it_o be_v only_o from_o its_o rosin_n digest_v and_o resolve_v in_o strong_a stomach_n hence_o it_o be_v that_o dog_n and_o such_o as_o have_v canine_a appetite_n do_v general_o purge_v after_o a_o great_a quantity_n of_o crude_a or_o rosinous_n opium_n whereas_o such_o as_o be_v not_o rosinous_n cause_v no_o such_o effect_n but_o of_o these_o matter_n more_o to_o your_o satisfaction_n hereafter_o three_o because_o it_o cause_v all_o effect_n that_o be_v quite_o contrary_a to_o those_o of_o grievous_a sensation_n it_o cause_v a_o ovation_n of_o the_o sensitive_a soul_n and_o spirit_n pain_n or_o grievous_a sensation_n a_o depression_n of_o spirit_n it_o cause_v euphory_n and_o pain_n weariness_n for_o what_o tire_v more_o than_o pain_n or_o labour_v in_o pain_n it_o cause_v good_a humour_n pain_n peevishness_n fretfulness_n and_o ill_a humour_n opium_n cause_v relaxation_n of_o all_o part_n pain_n contraction_n that_o cause_v free_a perspiration_n this_o check_v it_o that_o cause_v sleep_n this_o hinder_v it_o that_o cause_v contentation_n acquiescence_n this_o discontent_n and_o uneasiness_n that_o compose_v this_o discompose_v the_o spirit_n blood_n etc._n etc._n that_o cause_v flux_n by_o irritation_n etc._n etc._n this_o moderate_n or_o stop_v they_o that_o open_v the_o pore_n pain_n constr_v they_o opium_n prevent_v the_o shake_v fit_n in_o ague_n pain_n bring_v they_o on_o that_o cause_v a_o large_a and_o slow_a pulse_n this_o a_o quick_a hard_a and_o narrow_a pulse_n that_o cause_v a_o efflorescence_n of_o the_o skin_n this_o paleness_n that_o pleasant_a this_o unpleasant_a dream_n that_o still_v hiccough_n this_o cause_n they_o that_o take_v off_o contraction_n convulsion_n etc._n etc._n this_o cause_v they_o to_o be_v short_a opium_n cause_v all_o the_o effect_n of_o pleasant_a sensation_n and_o take_v off_o all_o the_o effect_n of_o grievous_a sensation_n what_o can_v be_v a_o more_o evident_a proof_n of_o its_o act_n by_o cause_v a_o pleasant_a sensation_n it_o be_v endless_a to_o mention_v all_o the_o proof_n that_o may_v be_v make_v to_o the_o same_o purpose_n from_o pleaser_n and_o displeaser_n of_o sensation_n therefore_o we_o fair_o conclude_v that_o opium_n do_v not_o operate_v by_o cause_v a_o grievovi_fw-la sensation_n and_o there_o be_v no_o other_o way_n leave_v by_o which_o it_o may_v operate_v it_o must_v operate_v by_o cause_v a_o pleasant_a sensation_n which_o be_v the_o true_a and_o plain_a reason_n why_o as_o have_v be_v show_v it_o take_v off_o pain_n and_o cause_v all_o effect_n quite_o contrary_a to_o that_o of_o grievous_a sensation_n irritation_n by_o acrimony_n etc._n etc._n which_o be_v most_o eminent_a upon_o the_o most_o sensible_a part_n as_o the_o stomach_n intestine_n venereal_a membrane_n skin_n etc._n etc._n as_o you_o may_v observe_v where_o the_o effect_n of_o opium_n be_v enumerate_v now_o gentle_a reader_n consider_v that_o contrary_n be_v the_o true_a cure_n of_o contrary_n what_o can_v then_o cure_v pain_n and_o all_o its_o effect_n better_a than_o pleasure_n it_o be_v very_o strange_a then_o that_o million_o for_o many_o age_n find_v opium_n cure_v or_o take_v off_o pain_n and_o all_o its_o effect_n above_o all_o thing_n shall_v not_o attribute_v its_o so_o do_v to_o its_o cause_v a_o pleasant_a sensation_n which_o be_v the_o direct_a contrary_n to_o pain_n especial_o since_o every_o man_n that_o take_v opium_n feel_v a_o actual_a pleasure_n upon_o take_v thereof_o pleasant_a dream_n a_o pleasant_a humour_n etc._n etc._n it_o may_v be_v say_v what_o if_o it_o be_v grant_v that_o opium_n operate_v by_o a_o please_a sensation_n which_o i_o will_v thank_v none_o for_o that_o have_v feel_v at_o stomach_n or_o reason_n at_o brain_n how_o be_v it_o possible_a that_o such_o pleasant_a sensation_n shall_v cause_v and_o explicate_v all_o the_o various_a strange_a wonderful_a mysterious_a and_o very_o often_o seem_o contradictory_n phenomena_n and_o effect_n of_o opium_n answer_n as_o easy_o as_o ever_o i_o explain_v any_o thing_n in_o nature_n especial_o if_o my_o tract_n of_o animal_n mechanism_n be_v publish_v but_o it_o be_v my_o misfortune_n that_o it_o be_v not_o however_o it_o shall_v not_o be_v the_o reader_n though_o it_o will_v put_v i_o to_o a_o great_a trouble_n to_o evade_v which_o be_v none_o of_o my_o intention_n by_o those_o word_n but_o rather_o to_o bespeak_v the_o reader_n be_v patience_n while_n i_o be_o premise_v some_o necessary_a praecognita_fw-la requisite_a to_o be_v know_v before_o i_o enter_v upon_o the_o explication_n of_o the_o wonderful_a and_o seem_o inexplicable_a effect_n of_o opium_n i_o therefore_o desire_v the_o reader_n be_v leave_v to_o premise_v some_o thing_n of_o the_o nature_n of_o sensation_n and_o sensitive_a pleasure_n in_o order_n to_o his_o more_o clear_a and_o ready_a understanding_n my_o explication_n of_o this_o mysterious_a and_o momentous_a matter_n look_v upon_o as_o so_o dark_a and_o abstruse_a a_o business_n to_o this_o day_n that_o some_o have_v not_o only_o yield_v it_o up_o as_o a_o thing_n hide_v from_o mankind_n but_o have_v earnest_o and_o serious_o argue_v that_o it_o act_v absolute_o by_o a_o occult_a quality_n reserve_v in_o a_o special_a manner_n as_o be_v the_o nature_n of_o spirit_n from_o our_o knowledge_n that_o it_o have_v be_v so_o hitherto_o i_o think_v none_o can_v deny_v as_o the_o circulation_n of_o the_o blood_n be_v for_o thousand_o of_o year_n though_o the_o very_a motion_n be_v see_v by_o million_o so_o as_o the_o cause_n of_o the_o operation_n of_o opium_n have_v be_v feel_v by_o a_o far_o great_a number_n it_o therefore_o will_v if_o i_o fail_v not_o in_o explain_v it_o appear_v so_o clear_a that_o it_o will_v be_v much_o wonder_v at_o like_o that_o of_o the_o circulation_n of_o the_o blood_n why_o so_o obvious_a a_o thing_n be_v not_o find_v by_o every_o one_o that_o use_v opium_n but_o whatever_o opium_n be_v god_n method_n be_v unsearchable_a and_o often_o his_o wise_a providence_n bestow_v good_a gift_n upon_o the_o unworthy_a that_o his_o free_a goodness_n may_v appear_v to_o who_o be_v all_o glory_n praise_n and_o thanksgiving_n for_o ever_o and_o ever_o amen_n note_v that_o while_o i_o be_o upon_o the_o
medium_n of_o sensation_n viz._n 3._o it_o be_v requisite_a or_o convenient_a at_o least_o that_o the_o air_n have_v a_o homogeneous_a continuity_n which_o much_o more_o advance_v it_o in_o convey_v impulse_n or_o impression_n than_o when_o it_o be_v discontinue_v divide_v or_o sever_v by_o other_o heterogeneous_a particle_n especial_o if_o these_o be_v in_o motion_n between_o the_o part_n of_o the_o air_n for_o than_o they_o very_o much_o disappoint_v and_o disgregate_v the_o impression_n make_v thereon_o therefore_o it_o be_v that_o we_o hear_v so_o much_o better_a after_o sunset_n or_o in_o the_o night_n especial_o the_o summertime_n than_o in_o the_o day_n when_o the_o particle_n of_o heat_n and_o other_o thereby_o raise_v do_v too_o much_o divide_v discontinue_v and_o disgregate_v the_o impression_n and_o the_o part_n of_o the_o air_n where_o you_o may_v observe_v how_o good_a and_o wise_a providence_n order_n hear_v to_o be_v more_o useful_a in_o the_o night_n when_o see_v fail_v it_o be_v a_o vulgar_a error_n though_o little_o think_v so_o to_o be_v that_o the_o cause_n of_o the_o difference_n of_o hear_v sound_v before_o and_o after_o sunset_n be_v the_o noise_n that_o be_v make_v in_o the_o daytime_n and_o the_o silence_n of_o the_o evening_n and_o night_n which_o one_o single_a instance_n though_o thousand_o may_v be_v give_v will_v full_o demonstrate_v viz._n in_o the_o famous_a and_o well-governed_n university_n and_o city_n of_o oxford_n there_o be_v scarce_o any_o noise_n make_v at_o the_o time_n of_o divine_a service_n on_o the_o lord_n day_n all_o people_n be_v either_o silent_a at_o church_n or_o shut_v up_o quiet_o and_o silent_o in_o their_o respective_a house_n or_o college_n the_o heat_n of_o the_o day_n in_o summertime_n but_o most_o the_o good_a order_n of_o the_o place_n cause_v it_o but_o after_o sunset_n most_o people_n be_v out_o walk_v and_o discourse_v or_o talk_v at_o their_o door_n arbour_n or_o garden_n and_o all_o child_n that_o noisy_a part_n of_o mankind_n be_v now_o permit_v to_o go_v out_o who_o act_n their_o part_n in_o play_v run_v call_v yawl_a and_o cry_v out_o one_o to_o another_o insomuch_o that_o all_o thing_n consider_v i_o can_v imagine_v but_o there_o must_v be_v in_o general_a a_o hundred_o time_n more_o noise_n make_v then_o than_o in_o the_o the_o time_n of_o divine_a service_n in_o the_o heat_n of_o the_o day_n yet_o may_v you_o notwithstanding_o all_o the_o noise_n heaâ—_n in_o the_o twilight_n any_o thing_n twice_o as_o far_o as_o in_o the_o time_n of_o divine_a service_n in_o the_o heat_n of_o the_o day_n i_o believe_v i_o may_v have_v say_v four_o or_o six_o time_n as_o far_o the_o same_o may_v be_v observe_v in_o any_o town_n or_o city_n that_o be_v keep_v in_o good_a order_n at_o the_o time_n of_o divine_a service_n or_o in_o camp_n etc._n etc._n upon_o several_a occasion_n it_o be_v not_o only_a consonant_n to_o reason_n that_o the_o air_n shall_v be_v so_o discontinue_v by_o the_o particle_n of_o heat_n etc._n etc._n but_o obvious_a to_o the_o sight_n that_o it_o be_v so_o for_o in_o a_o great_a heat_n the_o summertime_n and_o clear_a day_n you_o may_v see_v the_o very_a air_n in_o a_o waver_a tremulous_a motion_n which_o can_v not_o be_v see_v of_o itself_o without_o the_o mixture_n of_o other_o part_n for_o disgregation_n of_o part_n as_o you_o see_v even_o in_o pellucid_a homogeneous_a thing_n powder_v cause_v opacity_n iii_o the_o business_n or_o office_n of_o the_o organ_n of_o sensation_n in_o the_o oeconomy_n thereof_o be_v to_o receive_v and_o communicate_v the_o impression_n to_o the_o animal_n spirit_n with_o all_o the_o smartness_n they_o can_v it_o be_v manifest_a that_o in_o the_o membrane_n or_o organ_n tension_n be_v their_o main_a requisite_a hence_o it_o be_v that_o when_o the_o tympan_n of_o the_o ear_n be_v tense_n the_o cornea_n and_o other_o tunicle_n of_o the_o eye_n sufficient_o so_o we_o hear_v and_o see_v acute_o and_o accurate_o to_o that_o end_n god_n have_v give_v we_o a_o power_n to_o render_v the_o tympan_n more_o tense_n when_o we_o listen_v to_o contract_v the_o pupilla_fw-la of_o the_o eye_n when_o we_o look_v very_o intent_o etc._n etc._n and_o we_o see_v that_o when_o the_o cornea_n be_v relax_v as_o it_o be_v always_o when_o the_o eye_n look_v deadish_a as_o in_o sleep_n drunkenness_n faint_v fit_n etc._n etc._n yet_o than_o we_o either_o not_o see_v it_o at_o all_o or_o much_o worse_o so_o it_o be_v when_o the_o tympan_n be_v relax_v we_o also_o always_o put_v the_o tongue_n in_o a_o tense_n condition_n when_o we_o will_v taste_v a_o thing_n exact_o so_o when_o any_o part_n be_v relax_v by_o warmth_n etc._n etc._n we_o do_v not_o feel_v so_o well_o and_o nice_o as_o when_o the_o part_n be_v cold_a or_o more_o tense_n or_o rigid_a nor_o in_o sleep_n as_o when_o awake_a because_o all_o part_n be_v relax_v in_o sleep_n and_o contract_v when_o we_o be_v awake_a which_o manifest_o appear_v 1._o because_o we_o perspire_v less_o when_o we_o be_v awake_a than_o when_o asleep_o which_o happen_v because_o the_o pore_n be_v close_v by_o the_o contraction_n or_o constriction_n when_o we_o be_v awake_a and_o open_v or_o loosen_v by_o relaxation_n when_o asleep_a in_o all_o relaxation_n as_o that_o which_o happen_v by_o pleasure_n warmth_n leipothymy_n sleep_v etc._n etc._n we_o perspire_v more_o and_o less_o in_o contradiction_n by_o cold_a fear_v grief_n pain_n or_o any_o grievous_a sensation_n or_o passion_n 2._o because_o all_o part_n be_v firm_a when_o we_o be_v awake_a and_o more_o loose_a and_o flaccid_a when_o we_o be_v asleep_a none_o can_v doubt_v but_o firmness_n be_v from_o tension_n or_o contraction_n but_o in_o this_o matter_n you_o may_v expect_v far_a satisfaction_n by_o and_o by_o obj._n some_o may_v needless_o say_v how_o come_v tension_n and_o contraction_n to_o be_v concomitant_n or_o effect_n one_o of_o the_o other_o see_v we_o make_v thing_n more_o tense_n as_o a_o drum_n head_n etc._n etc._n by_o extension_n not_o contraction_n answ._n i_o purposely_o start_v this_o objection_n to_o clear_v the_o case_n therefore_o 1._o observe_v that_o violin-string_n will_v grow_v so_o tense_n as_o will_v any_o thing_n else_o of_o like_a nature_n by_o contraction_n in_o moist_a wether_n that_o tear_n they_o to_o piece_n sometime_o upon_o that_o account_n and_o always_o put_v they_o upon_o a_o great_a stress_n for_o when_o a_o thing_n be_v fix_v at_o both_o end_n it_o be_v the_o same_o thing_n to_o shorten_v or_o contract_n the_o string_n to_o render_v it_o tense_n as_o to_o take_v something_o from_o its_o length_n between_o those_o two_o fix_a point_n both_o the_o contraction_n and_o the_o wind_a do_v only_o take_v something_o of_o the_o length_n away_o that_o be_v between_o those_o two_o point_n where_o the_o end_n be_v fasten_v which_o cause_v a_o great_a stress_n of_o the_o shorten_a string_n to_o reach_v those_o two_o point_n that_o it_o be_v fasten_v to_o as_o suppose_v you_o have_v a_o string_n of_o 11_o inch_n long_o fasten_v at_o both_o end_n at_o the_o distance_n of_o 10_o inch_n it_o will_v be_v very_o loose_a then_o shorten_v it_o one_o inch_n by_o wind_v up_o so_o much_o or_o by_o some_o mean_n contract_v the_o string_n to_o 10_o inch_n or_o any_o way_n shorten_v it_o a_o inch_n than_o it_o will_v just_o reach_v the_o point_n and_o be_v tense_n if_o fasten_v at_o they_o so_o there_o be_v contraction_n necessary_o cause_v tension_n which_o be_v to_o be_v demonstrate_v it_o will_v be_v the_o same_o in_o effect_n if_o a_o string_n put_v round_o any_o thing_n be_v shorten_v by_o moisture_n or_o otherwise_o it_o must_v grow_v more_o tense_n and_o so_o must_v 500_o string_n if_o so_o shorten_v or_o a_o entire_a membrane_n that_o cover_v or_o include_v the_o whole_a thus_o membrane_n as_o a_o gut_n contract_v upon_o include_v air_n must_v when_o they_o contract_v grow_v more_o tense_n upon_o the_o include_v animal_n spirit_n in_o the_o nerve_n or_o otherwise_o for_o it_o be_v the_o same_o as_o force_v much_o air_n into_o a_o narrow_a or_o contract_a gut_n or_o bladder_n which_o must_v make_v they_o tense_n while_o the_o elastic_a body_n must_v thrust_v out_o the_o hard_a the_o more_o it_o be_v compress_v and_o that_o the_o membrane_n and_o all_o sensile_a part_n be_v more_o contract_v when_o we_o be_v awake_a do_v far_a most_o plain_o appear_v because_o 3._o the_o cornea_n of_o the_o eye_n which_o be_v a_o visible_a and_o certain_a sign_n of_o the_o relaxation_n of_o all_o the_o sensile_a part_n of_o the_o body_n be_v relax_v in_o sleep_n as_o any_o one_o may_v see_v for_o that_o be_v the_o cause_n of_o the_o deadness_n of_o the_o eye_n in_o sleep_n which_o upon_o awake_v be_v immediate_o go_v by_o the_o cornea_n
by_o squeeze_v in_o some_o case_n and_o stop_v it_o by_o shut_v the_o pore_n in_o other_o case_n 10._o it_o be_v by_o it_o that_o contraction_n that_o fear_v cold_a etc._n etc._n close_v the_o pore_n and_o repel_v the_o blood_n staunch_a bleed_a so_o happen_v also_o a_o great_a contraction_n of_o the_o pupil_n of_o the_o eye_n by_o the_o same_o cause_n 11._o it_o be_v the_o violence_n of_o this_o contraction_n upon_o fear_n terror_n pain_n cold_a etc._n etc._n close_v the_o small_a vessel_n of_o the_o animal_n spirit_n and_o thereby_o repel_v they_o cause_v the_o shiver_a in_o those_o case_n by_o the_o renitency_n of_o the_o elastic_a animal_n spirit_n spring_v back_o again_o toties_fw-la quoties_fw-la have_v gain_v more_o elastic_a force_n by_o the_o very_a compression_n itself_o which_o that_o contraction_n cause_n so_o that_o by_o reason_n of_o the_o dubious_a velitation_n or_o skirmish_v between_o the_o repel_v contraction_n and_o the_o spring_a spirit_n happen_v a_o tremulous_a motion_n as_o of_o quaver_v spring_n which_o shiver_a in_o ague-fits_a do_v former_o lead_v i_o to_o the_o situation_n of_o the_o cause_n of_o ague_n when_o i_o write_v my_o book_n de_fw-fr febribus_fw-la intermittentibus_fw-la in_o the_o angustiae_fw-la at_o the_o end_n of_o the_o vessel_n which_o terminate_v in_o the_o membrane_n the_o grievous_a sensation_n of_o which_o cause_v all_o the_o shiver_a that_o happen_v in_o any_o case_n to_o animal_n 12._o by_o the_o same_o contraction_n when_o very_o violent_a and_o of_o the_o whole_a body_n cold_a sweat_v happen_v in_o pain_n fear_v terror_n etc._n etc._n while_o it_o violent_o squeeze_v out_o the_o outmost_a and_o therefore_o cold_a moisture_n of_o our_o body_n as_o laundress_n do_v water_n out_o of_o wet_a linen_n by_o contortion_n thus_o if_o you_o dip_v one_o half_a of_o a_o wet_a cold_a sheet_n in_o hot_a water_n wrap_v the_o hot_a side_n within_o the_o cold_a or_o let_v a_o warm_a sheet_n that_o be_v contort_a cool_a on_o the_o outside_n of_o it_o and_o then_o wring_v it_o as_o woman_n do_v linen_n the_o water_n that_o first_o exudate_n will_v be_v cold_a for_o in_o this_o case_n the_o close_n of_o the_o pore_n avail_v nothing_o to_o hinder_v it_o as_o long_o as_o the_o express_a force_n master_n it_o more_o especial_o in_o animal_n body_n wherein_o the_o part_n be_v so_o contrive_v that_o humour_n design_v for_o exoretion_n can_v well_o return_v and_o therefore_o must_v upon_o contraction_n run_v out_o hence_o it_o be_v that_o alum_n or_o vitriol_n which_o be_v very_o astringent_a and_o therefore_o close_a the_o pore_n will_v notwithstanding_o cause_v the_o mouth_n or_o nose_n to_o run_v very_o plentiful_o with_o moisture_n by_o contract_v all_o the_o membrane_n about_o the_o mouth_n or_o nose_n and_o thereby_o squeeze_v out_o the_o moisture_n design_v to_o be_v excern_v which_o can_v return_v because_o the_o part_n be_v contrive_v against_o the_o return_n or_o readmittance_n thereof_o whereas_o alum_n or_o vitriol_n will_v staunch_v or_o stop_v blood_n by_o the_o same_o contraction_n because_o it_o may_v return_v as_o not_o be_v design_v to_o be_v excern_v either_o into_o the_o artery_n and_o so_o pass_v by_o other_o branch_n thereof_o or_o which_o be_v more_o ready_a and_o natural_a keep_v its_o course_n into_o the_o vein_n so_o the_o two_o riddle_n that_o i_o have_v know_v some_o proud_a physician_n amaze_v at_o though_o but_o trifle_n of_o alum_n and_o vitriol_n cause_v the_o spital_n etc._n etc._n to_o come_v out_o instead_o of_o stop_v it_o by_o their_o astringency_n and_o their_o stop_a blood_n at_o nose_n at_o the_o same_o time_n they_o cause_v the_o snot_n or_o other_o humour_n to_o run_v out_o be_v unfold_v 13._o it_o be_v by_o this_o mighty_a contraction_n grow_v to_o a_o enormous_a degree_n that_o the_o animal_n spirit_n be_v violent_o compress_v grow_v exceed_o irrequiete_a as_o upon_o convulsion_n in_o great_a pain_n or_o very_o grievous_a sensation_n at_o stomach_n etc._n etc._n while_o the_o sensitive_a soul_n compress_v they_o with_o mighty_a force_n and_o somewhat_o disorderly_a and_o uneven_o because_o of_o the_o confusion_n and_o hurry_n he_o be_v in_o to_o relieve_v the_o animal_n they_o by_o their_o springiness_n fling_v up_o and_o down_o with_o great_a vigour_n this_o make_v convulsive_a motion_n have_v great_a strength_n 14._o the_o body_n under_o this_o contraction_n be_v manifest_o shrink_v by_o measure_n especial_o when_o the_o sensation_n be_v very_o grievous_a but_o most_o of_o all_o if_o they_o cause_v a_o general_a convulsion_n which_o i_o manifest_o observe_v in_o a_o little_a bitch_n that_o be_v convulsive_a all_o over_o for_o three_o hour_n and_o be_v just_a expire_n when_o i_o give_v she_o the_o sal_fw-la volat._n oleo_n of_o opium_n which_o perfect_o restore_v she_o by_o relax_v the_o vessel_n some_o may_v think_v it_o strange_a that_o nature_n shall_v contrive_v a_o more_o nice_a and_o smart_a sensation_n which_o the_o contraction_n of_o the_o vessel_n of_o the_o animal_n spirit_n must_v cause_v by_o compress_v they_o etc._n etc._n in_o pain_n and_o by_o it_o which_o become_v so_o much_o the_o more_o acute_a whereas_o one_o will_v judge_v that_o nature_n will_v rather_o contrive_v its_o ease_n than_o improve_v its_o smart_n you_o be_v to_o know_v that_o the_o pain_n be_v in_o order_n to_o relieve_v the_o animal_n by_o exciting_a all_o its_o power_n to_o defend_v expel_v or_o reject_v the_o cause_n and_o that_o without_o a_o grievous_a sensation_n the_o sensitive_a soul_n be_v neither_o mind_v nor_o excite_v to_o do_v it_o and_o the_o more_o the_o pain_n be_v the_o more_o it_o be_v stir_v up_o to_o self-preservation_n and_o as_o be_v show_v the_o more_o vigorous_a do_v its_o motion_n grow_v by_o the_o compression_n of_o the_o elastic_a spirit_n to_o perform_v that_o work_n so_o nature_n not_o regard_v the_o pain_n which_o be_v rather_o for_o good_a as_o much_o as_o take_v away_o the_o cause_n advance_v that_o for_o this_o purpose_n like_o a_o wise_a physician_n who_o find_v a_o grievance_n at_o stomach_n not_o sufficient_a to_o excite_v effectual_a vomit_v to_o throw_v away_o the_o grieve_v cause_n add_v to_o the_o grievance_n by_o give_v a_o vomit_n which_o because_o as_o be_v say_v nature_n be_v proportionable_o excite_v to_o and_o invigorate_v for_o self-preservation_n sufficient_o solicit_v and_o enable_v it_o by_o a_o strong_a contraction_n to_o reject_v the_o grieve_v matter_n as_o the_o great_a the_o relaxation_n be_v the_o more_o be_v the_o rest_n of_o all_o part_n and_o the_o weak_a the_o animal_n spirit_n because_o less_o compress_v the_o gentle_a be_v all_o motion_n as_o you_o see_v in_o sleep_n consequent_o the_o less_o be_v the_o expense_n of_o spirit_n so_o that_o in_o sleep_n we_o generate_v more_o than_o we_o spend_v and_o be_v thereby_o recruit_v so_o the_o more_o the_o contraction_n be_v the_o more_o violent_a be_v the_o motion_n of_o the_o heart_n intestine_n and_o of_o all_o part_n and_o consequent_o the_o expense_n of_o spirit_n be_v the_o great_a therefore_o it_o can_v be_v no_o wonder_n that_o contraction_n do_v cause_n great_a commotion_n of_o spirit_n diary_n fever_n etc._n etc._n when_o you_o consider_v 1._o that_o the_o sensitive_a soul_n be_v by_o the_o grievous_a sensation_n etc._n etc._n that_o cause_n they_o put_v upon_o a_o great_a fret_v concern_v and_o hurry_v to_o defend_v the_o animal_n and_o lay_v about_o he_o all_o manner_n of_o way_n for_o self-preservation_n 2._o that_o the_o animal_n spirit_n be_v by_o mean_n of_o great_a compression_n cause_v by_o the_o defensive_a contraction_n in_o a_o very_a forcible_a springiness_n which_o cause_v all_o the_o action_n that_o be_v continual_a involuntary_a and_o of_o course_n to_o be_v perform_v with_o great_a violence_n proportionable_a to_o its_o compress_a elasticity_n beside_o that_o 3._o the_o systole_n of_o the_o heart_n be_v oftener_o repeat_v all_o which_o conspire_v to_o cause_v great_a commotion_n upon_o grievous_a sensation_n whereby_o diary_n fever_n etc._n etc._n be_v cause_v which_o be_v easy_o and_o natural_o cure_v by_o sleep_n or_o relaxation_n at_o present_a compose_v and_o quiet_v those_o perturbation_n who_o know_v though_o it_o be_v not_o my_o business_n to_o discuss_v it_o at_o present_a but_o that_o the_o contraction_n in_o the_o cold_a fit_n of_o ague_n have_v a_o great_a hand_n in_o cause_v the_o hot_a one_o how_o otherwise_o shall_v opium_n by_o only_o take_v away_o the_o grievous_a sensation_n of_o the_o cold_a fit_n take_v off_o or_o prevent_v the_o hot_a fit_n also_o but_o of_o this_o in_o my_o often-mentioned_n tract_n though_o not_o so_o often_o as_o it_o grieve_v i_o that_o it_o be_v not_o publish_v how_o reasonable_o may_v we_o now_o expect_v that_o pleasant_a sensation_n may_v cause_v quite_o contrary_a effect_n to_o that_o of_o grievous_a sensation_n viz._n relaxation_n and_o all_o its_o effect_n
contract_v it_o be_v round_o even_o polite_a and_o true_o represent_v thing_n 11._o deadness_n of_o the_o eye_n to_o the_o view_n be_v as_o have_v be_v show_v from_o the_o laxity_n of_o the_o cornea_n which_o make_v it_o flag_n lie_v loose_a look_v dull_o and_o not_o due_o reflect_v a_o smart_n and_o brisk_a speck_n of_o light_n as_o it_o do_v when_o tense_n round_o and_o polite_a by_o its_o contraction_n on_o the_o contain_v humour_n which_o then_o due_o fill_v it_o 12._o falter_v of_o the_o tongue_n be_v from_o the_o same_o relaxation_n as_o in_o drunken_a person_n 13._o a_o sopor_fw-la be_v from_o the_o same_o relaxation_n over_o all_o the_o sensile_a part_n of_o the_o body_n by_o which_o mean_v sense_n and_o motion_n be_v diminish_v or_o lose_v by_o the_o expansion_n of_o the_o animal_n spirit_n which_o as_o have_v be_v say_v be_v not_o due_o compress_v become_v unfit_a for_o both_o at_o the_o same_o time_n 14._o a_o slow_a and_o wide_a pulse_n be_v from_o the_o same_o cause_n because_o the_o say_a relaxation_n permit_v the_o artery_n to_o widen_v and_o the_o animal_n spirit_n to_o expand_v and_o consequent_o render_v the_o motion_n of_o the_o heart_n slow_a which_o be_v the_o cause_n of_o the_o pulse_n 15._o a_o high_a colour_n or_o efflorescence_n of_o the_o skin_n have_v be_v explain_v 16._o looseness_n of_o the_o jaw_n and_o lip_n be_v from_o the_o same_o relaxation_n as_o be_v show_v and_o so_o be_v 17._o intumescence_n of_o the_o lip_n as_o have_v be_v show_v 18._o difficulty_n of_o breathe_v may_v be_v from_o two_o different_a cause_n either_o by_o the_o relaxation_n weaken_v the_o requisite_a motion_n for_o want_n of_o compressure_n of_o the_o animal_n spirit_n and_o by_o the_o flaccity_n of_o the_o part_n themselves_o or_o by_o a_o great_a grievance_n at_o stomach_n upon_o the_o account_n of_o the_o rosin_n stick_v to_o it_o and_o cause_v a_o convulsion_n of_o those_o part_n both_o which_o may_v happen_v 19_o fury_n and_o madness_n may_v also_o happen_v either_o by_o the_o exalt_a pleasure_n of_o its_o titillation_n as_o in_o drunkard_n who_o therefore_o scarce_o know_v what_o they_o do_v the_o mind_n be_v as_o be_v say_v alienate_v or_o it_o may_v happen_v as_o i_o have_v often_o know_v a_o kind_n of_o madness_n to_o be_v produce_v by_o a_o great_a grievance_n at_o stomach_n which_o may_v well_o be_v from_o the_o rosin_n grieve_v and_o teaze_v the_o nice_o sensile_a stomach_n they_o may_v be_v easy_o distinguish_v one_o viz._n that_o from_o the_o rosin_n at_o stomach_n be_v with_o great_a distress_n anxiety_n convulsion_n etc._n etc._n and_o the_o other_o without_o any_o 20._o venereal_a fury_n proceed_v from_o the_o high_a titillation_n of_o the_o venereal_a membrane_n by_o the_o volatile_a salt_n of_o so_o much_o opium_n as_o if_o cantharides_n bee_n &c_n &c_n be_v take_v internal_o but_o that_o these_o can_v so_o agreeable_o titillate_v those_o part_n as_o opium_n do_v who_o volatile_a particle_n be_v render_v more_o please_a by_o oily_a one_o and_o therefore_o much_o of_o the_o nature_n of_o semen_n virile_a 21._o priapism_n be_v cause_v by_o the_o same_o continual_a titillation_n 22._o violent_a itch_n of_o the_o skin_n be_v cause_v by_o the_o same_o tickle_a volatile_a particle_n in_o great_a abundance_n proportionable_a to_o the_o excessive_a do_v 23._o nauseas_fw-la be_v cause_v by_o the_o rosin_n stick_v at_o and_o solicit_v the_o stomach_n to_o vomit_v 24._o swimmings_n in_o the_o head_n be_v by_o conseâ—it_n because_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o be_v observe_v in_o many_o case_n from_o a_o grieve_a stomach_n upon_o a_o tendency_n to_o vomit_v as_o when_o it_o be_v overload_v with_o wine_n or_o indigestible_a victual_n or_o when_o person_n be_v sea_n or_o coach-sick_a etc._n etc._n for_o it_o be_v not_o in_o these_o last_o case_n because_o the_o brain_n be_v offend_v as_o people_n imagine_v that_o they_o be_v sick_a or_o vomit_n but_o the_o swim_v in_o the_o head_n and_o offence_n of_o the_o brain_n happen_v because_o the_o stomach_n be_v offend_v by_o the_o motion_n of_o the_o coach_n or_o ship_n by_o reason_n of_o its_o most_o exquisite_a sensation_n which_o the_o effluvias_fw-la of_o a_o cat_n pestiferous_a particle_n and_o commotion_n cause_v by_o mear_v passion_n can_v and_o do_v offend_v as_o be_v say_v so_o as_o to_o cause_v vomit_n anxiety_n etc._n etc._n much_o more_o than_o may_v the_o motion_n of_o a_o ship_n or_o coach_n do_v it_o i_o shall_v not_o here_o enter_v into_o controversy_n with_o those_o that_o assert_v that_o it_o be_v the_o head_n be_v first_o offend_v in_o a_o coach_n or_o ship_n it_o be_v sufficient_a for_o my_o purpose_n that_o grievance_n at_o stomach_n do_v common_o cause_n swimmings_n in_o the_o head_n for_o take_v off_o those_o grievance_n cure_v they_o as_o eat_v when_o it_o be_v from_o the_o grievance_n of_o hunger_n or_o wind_n at_o stomach_n and_o discharge_v the_o stomach_n of_o a_o great_a load_n of_o wine_n ale_z or_o indigestible_a matter_n when_o such_o thing_n cause_v it_o do_v cure_v such_o swimming_n in_o the_o head_n the_o way_n how_o grievance_n at_o stomach_n do_v cause_n those_o swimming_n be_v by_o cause_v a_o contraction_n as_o all_o grievance_n do_v but_o especial_o those_o at_o stomach_n of_o the_o membrane_n of_o the_o brain_n as_o it_o do_v of_o all_o other_o but_o main_o of_o these_o because_o very_o sensile_a by_o which_o mean_v the_o animal_n spirit_n be_v compress_v grow_v more_o irrequiete_a and_o skip_a up_o and_o down_o and_o the_o compression_n not_o be_v continual_o alike_o in_o general_n or_o the_o artery_n afford_v a_o uneven_a and_o forcible_a supply_n of_o they_o or_o fume_n from_o the_o blood_n by_o the_o compression_n nor_o affect_v all_o part_n of_o the_o brain_n with_o equal_a force_n because_o the_o pleasure_n endeavour_n to_o relax_v etc._n etc._n there_o must_v thence_o arise_v eddy_n vortices_fw-la or_o whirl_v thereof_o which_o cause_n swimmings_n vertigo_n &c._n &c._n according_a as_o they_o happen_v to_o be_v move_v that_o they_o happen_v from_o such_o contraction_n be_v manifest_a 1._o because_o the_o grievance_n at_o stomach_n can_v add_v nothing_o else_o to_o the_o brain_n or_o its_o membrane_n 2._o because_o they_o be_v take_v off_o by_o please_v the_o stomach_n and_o consequent_o by_o relaxation_n as_o by_o a_o glass_n of_o wine_n victual_n a_o opiate_n that_o be_v not_o resinous_a etc._n etc._n it_o be_v here_o well_o worth_a your_o notice_n that_o all_o consent_n of_o part_n a_o thing_n much_o admire_v be_v only_o by_o contraction_n or_o relaxation_n which_o sudden_o affect_v the_o whole_a systeme_n of_o the_o nerve_n and_o membrane_n 25._o vertigo_n be_v from_o the_o same_o cause_n 26._o vomit_n be_v cause_v as_o be_v say_v by_o the_o great_a grievance_n of_o the_o acrimonious_a rosin_n stick_v to_o the_o coat_n of_o the_o stomach_n 27._o hiccongh_n be_v from_o the_o same_o cause_n which_o happen_v upon_o the_o decay_n of_o power_n vigorous_o to_o vomit_v dwindle_v into_o those_o fruitless_a convulsive_a subsultory_n jerâ—_n or_o half_a endeavour_n 28._o distress_n and_o anxiety_n must_v necessary_o attend_v such_o a_o grievous_a sensation_n and_o desection_n of_o nature_n endeavour_v as_o be_v overbear_v and_o disable_v to_o work_v for_o itself_o 29._o a_o turbulent_a pulse_n must_v be_v a_o effect_n of_o the_o forego_n tumult_n 30._o convulsion_n happen_v as_o be_v show_v by_o the_o enormous_a compression_n of_o the_o animal_n spirit_n by_o reason_n of_o the_o violent_a contraction_n upon_o the_o great_a grievance_n by_o the_o rosin_n at_o stomach_n which_o cause_v they_o to_o skip_v and_o fling_v up_o and_o down_o very_o forcible_o under_o the_o squeeze_v of_o the_o compression_n and_o possible_o skirmish_v under_o the_o vicissitude_n of_o it_o and_o relaxation_n 31._o faint_n and_o leipothymy_n be_v cause_v as_o have_v be_v explain_v by_o the_o sensitive_a soul_n be_v overtired_n by_o the_o fatigue_n of_o defensive_a contraction_n and_o yield_v himself_o to_o rest_n from_o all_o contraction_n as_o the_o last_o relief_n etc._n etc._n whereupon_o sense_n and_o motion_n do_v fail_v for_o want_v of_o compression_n to_o render_v the_o spirit_n springy_a active_a and_o fit_a for_o the_o purpose_n 32._o cold_a breath_n be_v but_o a_o necessary_a consequence_n of_o the_o loss_n of_o motion_n and_o therefore_o of_o heat_n by_o such_o leipothymy_n and_o faint_n 33._o death_n be_v cause_v two_o manner_n of_o way_n that_o be_v either_o by_o a_o utter_a expense_n of_o spirit_n and_o thereupon_o a_o dereliction_n or_o extinction_n of_o the_o sensitive_a soul_n by_o reason_n of_o those_o distress_n and_o fatigue_n upon_o the_o account_n of_o the_o invincible_a rosin_n or_o by_o too_o much_o relaxation_n disable_n all_o the_o motion_n of_o the_o body_n as_o in_o such_o as_o die_v be_v dead_a drink_v
the_o first_o symptom_n of_o a_o nausea_n vomit_v etc._n etc._n be_v most_o to_o be_v depend_v upon_o for_o it_o may_v happen_v sometime_o as_o after_o a_o great_a do_v that_o the_o rosin_n may_v stick_v etc._n etc._n and_o the_o relaxation_n be_v excessive_a also_o second_o when_o you_o be_v satisfy_v that_o it_o be_v the_o rosin_n at_o stomach_n that_o cause_v the_o mischief_n and_o not_o bare_a relaxation_n you_o be_v not_o to_o promote_v or_o stop_v the_o vomit_n lest_o in_o the_o first_o case_n you_o torment_n and_o endanger_v the_o person_n to_o no_o purpose_n for_o the_o rosin_n do_v general_o if_o not_o always_o stick_v too_o fast_o and_o too_o little_a in_o bulk_n to_o be_v shake_v off_o by_o vomit_v or_o the_o contraction_n of_o the_o stomach_n as_o appear_v by_o the_o tidious_a vomit_n that_o happen_v thereupon_o and_o the_o nature_n of_o the_o thing_n so_o that_o i_o believe_v it_o be_v seldom_o or_o never_o carry_v off_o that_o way_n and_o that_o when_o people_n be_v at_o last_o relieve_v it_o be_v by_o a_o gradual_a waste_n dissolution_n or_o digestion_n of_o the_o rosin_n as_o in_o great_a measure_n appear_v also_o by_o its_o purge_v some_o person_n after_o vomit_v and_o a_o long_a time_n after_o it_o be_v take_v in_o a_o considerable_a quantity_n nor_o be_v you_o to_o stop_v the_o vomit_v as_o not_o know_v what_o nature_n may_v advantage_n herself_o thereby_o but_o indeed_o it_o be_v more_o than_o you_o can_v do_v general_o speak_v if_o not_o always_o while_o the_o rosin_n teaze_v urge_v and_o sting_v the_o stomach_n it_o evident_o follow_v that_o the_o cure_n must_v consist_v in_o the_o dissolution_n of_o the_o rosin_n for_o this_o purpose_n you_o have_v four_o effectual_a dissolver_n of_o the_o rosin_n as_o you_o may_v observe_v from_o the_o chapter_n of_o the_o preparation_n of_o opium_n that_o may_v be_v use_v with_o safety_n in_o a_o moderate_a do_v 1._o lixivial_a salt_n whereof_o the_o best_a be_v salt_n of_o tartar_n 2._o sulphureous_a spirit_n whereof_o the_o best_a be_v high_a rectify_a spirit_n of_o wine_n 3._o the_o yolk_n of_o egg_n whereof_o the_o best_a be_v the_o yolk_n of_o a_o rear_n new_o lay_v egg._n 4._o white_a soap_n or_o rather_o the_o sapo_n tartareus_fw-la with_o these_o judicious_o use_v you_o may_v by_o god_n blessing_n relieve_v and_o cure_v the_o person_n grieve_v with_o the_o rosin_n or_o noxious_a part_n of_o opium_n 1._o give_v with_o all_o possible_a speed_n one_o scruple_n of_o salt_n of_o tartar_n in_o a_o spoonful_n or_o two_o of_o brandy_n or_o some_o other_o hot_a cordial_a spirit_n if_o spirit_n of_o wine_n be_v too_o hot_a place_v the_o person_n in_o the_o very_a same_o posture_n that_o he_o be_v in_o when_o he_o take_v the_o opiate_n that_o it_o may_v fall_v direct_o upon_o its_o rosin_n which_o most_o probable_o stick_v where_o the_o opiate_n first_o fall_v upon_o the_o coat_n of_o the_o stomach_n then_o stay_v for_o a_o minute_n or_o two_o and_o give_v a_o spoonful_n or_o two_o of_o the_o brandy_n or_o cordial_n with_o if_o need_v be_v the_o salt_n of_o tartar_n in_o it_o if_o you_o find_v cause_n either_o because_o the_o first_o dose_n be_v vomit_v or_o that_o the_o quantity_n of_o the_o rosin_n be_v great_a or_o that_o the_o person_n grow_v worse_a you_o may_v often_o repeat_v it_o for_o we_o must_v not_o be_v spare_v in_o safe_a thing_n in_o dangerous_a case_n i_o think_v it_o may_v well_o be_v repeat_v after_o every_o vomit_v toties_fw-la quoties_fw-la i_o have_v a_o great_a opinion_n of_o the_o yolk_n of_o a_o egg_n in_o these_o case_n not_o only_o because_o it_o do_v as_o the_o other_o thing_n mix_v with_o the_o rosin_n but_o because_o be_v of_o a_o good_a consistence_n it_o stick_v to_o it_o and_o fasten_v upon_o it_o the_o better_o and_o be_v not_o so_o clear_o shake_v from_o it_o by_o every_o vomit_n as_o liquid_n be_v therefore_o i_o think_v it_o very_o useful_a to_o be_v give_v now_o and_o then_o immediate_o after_o vomit_v however_o let_v no_o other_o food_n be_v give_v but_o it_o and_o be_v sure_a to_o use_v it_o when_o you_o have_v not_o the_o aforesaid_a thing_n i_o believe_v it_o will_v be_v find_v by_o experience_n which_o be_v yet_o much_o want_v because_o it_o have_v not_o be_v use_v to_o be_v the_o very_o best_a help_n in_o these_o case_n for_o the_o aforesaid_a reason_n and_o because_o its_o fine_a oiliness_n will_v correct_v the_o volatile_a salt_n of_o opium_n i_o can_v imagine_v but_o white_a soap_n or_o rather_o the_o sapo_n tartareus_fw-la if_o you_o have_v it_o by_o you_o may_v be_v of_o very_o good_a use_n to_o dissolve_v and_o carry_v off_o the_o rosin_n 2._o when_o the_o vomit_v begin_v to_o cease_v you_o must_v distinguish_v well_o whether_o it_o be_v because_o the_o person_n be_v better_a and_o the_o stomach_n discharge_v of_o the_o rosin_n or_o because_o tire_a nature_n yield_v itself_o to_o rest_n by_o a_o sort_n of_o succumbency_n to_o the_o fatigue_n or_o leipothymy_n you_o may_v easy_o distinguish_v these_o case_n for_o in_o the_o first_o case_n every_o thing_n seem_v better_a and_o in_o the_o last_o worse_o save_v that_o the_o vomit_v cease_v which_o be_v a_o endeavour_n of_o more_o vigorous_a nature_n and_o therefore_o its_o fail_n be_v now_o a_o ill_a sign_n in_o this_o case_n good_a old_a wine_n and_o spirituoâ—_n cordial_n which_o may_v rouse_v and_o invigorate_v nature_n and_o also_o engage_v with_o the_o rosin_n by_o their_o sulphureous_a spirit_n must_v be_v of_o excellent_a use._n note_v that_o if_o you_o want_v salt_n of_o tartar_n other_o lixivial_a salt_n may_v serve_v as_o those_o of_o wormwood_n broom_n etc._n etc._n only_o you_o must_v give_v at_o least_o one_o three_o more_o and_o in_o case_n of_o great_a haste_n and_o urgency_n you_o may_v give_v the_o very_a ash_n of_o wormwood_n broom_n or_o any_o vegetable_a in_o 2_o or_o 3_o time_n the_o quantity_n as_o the_o salt_n be_v to_o be_v give_v in_o 2_o or_o 3_o spoonful_n of_o brandy_n or_o a_o glass_n of_o old_a wine_n or_o both_o mix_v together_o for_o the_o very_a roughness_n of_o the_o ash_n will_v in_o some_o measure_n contribute_v to_o wear_v off_o the_o rosin_n and_o thereby_o assist_v the_o lixivial_a salt_n that_o be_v in_o they_o 3._o if_o the_o quantity_n of_o the_o resinous_n opium_n be_v great_a it_o will_v be_v convenient_a when_o you_o perceive_v the_o vomit_v begin_v to_o abate_v to_o give_v as_o much_o of_o daffee_n elixir_n or_o tinctura_fw-la sacra_fw-la make_v in_o some_o spirituous_a liquor_n as_o do_v usual_o give_v six_o stool_n it_o be_v best_o purge_v with_o a_o liquid_a because_o speedy_a in_o operation_n and_o that_o it_o shall_v be_v spirituous_a to_o help_v the_o dissolution_n of_o the_o rosin_n 1._o note_v that_o you_o also_o take_v care_v not_o to_o be_v too_o busy_a with_o spirituous_a liquor_n when_o they_o be_v much_o relax_v and_o have_v such_o symptom_n as_o drunken_a people_n have_v especial_o if_o they_o appear_v in_o a_o high_a degree_n for_o too_o much_o of_o they_o may_v promote_v the_o relaxation_n 2._o note_v that_o in_o faint_n or_o leipothymy_n after_o such_o vomit_n and_o struggle_v of_o nature_n you_o must_v not_o so_o much_o excite_v they_o by_o grievous_a sensation_n as_o pinch_v prick_a etc._n etc._n for_o those_o leipothymy_n be_v as_o be_v say_v a_o sort_n of_o recruit_v as_o sleep_n be_v and_o therefore_o the_o last_o refuge_n of_o nature_n for_o that_o end_n but_o with_o spirituous_a and_o comfortable_a thing_n as_o know_v that_o there_o be_v a_o awake_n by_o recruit_v which_o be_v natural_a as_o well_o as_o by_o grievous_a sensation_n which_o be_v force_v and_o unnatural_a as_o have_v be_v show_v ii_o to_o cure_v the_o effect_n of_o too_o much_o relaxation_n by_o a_o excessive_a do_v etc._n etc._n first_o you_o must_v be_v satisfy_v that_o the_o ill_a effect_n thereof_o be_v from_o too_o much_o relaxation_n 1._o by_o consider_v the_o preparation_n of_o opium_n that_o be_v take_v for_o if_o you_o find_v that_o it_o be_v such_o as_o have_v the_o rosin_n due_o separate_v from_o it_o you_o may_v be_v sure_a that_o the_o ill_a effect_n be_v only_o from_o relaxation_n because_o the_o do_v be_v too_o great_a or_o if_o it_o be_v a_o preparation_n that_o have_v the_o rosin_n so_o subdue_v or_o alter_v as_o you_o find_v direct_v to_o render_v it_o safe_a you_o may_v presume_v the_o ill_a effect_n be_v from_o over_o relaxation_n for_o such_o preparation_n be_v otherwise_o safe_a and_o innocent_a except_o when_o the_o largeness_n of_o the_o do_v as_o that_o of_o good_a wine_n cause_v too_o much_o relaxation_n 2._o by_o the_o symptom_n which_o be_v these_o viz._n alienation_n of_o the_o mind_n loss_n of_o memory_n stupidity_n sleepiness_n sopor_n failures_n of_o the_o sense_n as_o
gentian_a wine_n two_o dram_fw-la of_o the_o chalybeate_a wine_n describe_v in_o the_o london_n dispensatory_a increase_v about_o a_o scruple_n every_o day_n till_o you_o come_v to_o half_a a_o ounce_n which_o take_v for_o two_o month_n at_o least_o afterward_o decrease_v as_o you_o increase_v till_o you_o come_v to_o one_o drachm_n and_o so_o give_v over_o but_o if_o you_o find_v oâ—osion_n you_o may_v continue_v that_o course_n long_o or_o as_o long_o as_o your_o physician_n think_v fit_a after_o all_o you_o may_v use_v a_o glass_n of_o claret_n when_o faint_a but_o be_v sure_a to_o be_v moderate_a and_o not_o run_v from_o one_o excess_n to_o another_o as_o for_o the_o acrimony_n of_o blood_n that_o be_v more_o during_o the_o take_v of_o opium_n and_o will_v soon_o after_o gradual_o wear_v off_o especial_o by_o the_o course_n direct_v if_o not_o camphire_n be_v the_o adequate_a remedy_n of_o which_o with_o equal_a part_n of_o white_a rosin_n and_o q._n s._n of_o mucilage_n of_o gum._n tragac._n you_o may_v make_v pill_n of_o â—_o grain_n weight_n take_v 4_o of_o they_o every_o night_n at_o bedtime_n in_o a_o rear_n yolk_n of_o a_o egg_n as_o long_o as_o it_o be_v necessary_a for_o camphire_n by_o its_o fine_a sulphur_n correct_v the_o volatile_a acrimony_n of_o cantharides_n opium_n etc._n etc._n and_o so_o allay_v titillation_n to_o venery_n etc._n etc._n as_o be_v observe_v iv_o the_o ill_a effect_n of_o a_o sudden_a leave_v off_o of_o opium_n as_o anxiety_n distress_n depression_n of_o spirit_n which_o as_o be_v say_v be_v very_o dangerous_a be_v remedy_v no_o other_o way_n but_o either_o 1._o by_o return_v to_o the_o use_v of_o opium_n which_o be_v a_o most_o certain_a cure_n and_o afterward_o if_o you_o please_v give_v over_o the_o use_n of_o it_o after_o the_o manner_n that_o i_o direct_v which_o you_o will_v find_v to_o be_v safe_a nor_o can_v i_o advise_v you_o to_o trust_v any_o other_o method_n of_o leave_v it_o off_o unless_o it_o be_v 2._o by_o substitute_v wine_n instead_o of_o opium_n which_o be_v not_o quite_o so_o safe_a or_o certain_a your_o best_a method_n of_o use_v it_o be_v to_o drink_v a_o good_a glass_n of_o it_o so_o often_o as_o to_o keep_v the_o comfort_n thereof_o at_o stomach_n continual_o that_o so_o it_o may_v answer_v the_o more_o permanent_a effect_n of_o opium_n and_o keep_v you_o from_o a_o faint_a condition_n but_o see_v also_o that_o this_o course_n be_v not_o convenient_a to_o be_v continue_v long_o you_o must_v gradual_o lessen_v the_o do_v of_o this_o as_o you_o be_v direct_v to_o do_v that_o of_o opium_n till_o you_o come_v to_o take_v none_o or_o at_o least_o a_o moderate_a and_o wholesome_a quantity_n note_v that_o if_o such_o as_o use_v to_o take_v opium_n be_v even_o almost_o expire_a for_o want_n of_o it_o you_o must_v to_o prevent_v imminent_a death_n give_v a_o liquid_a preparation_n thereof_o to_o the_o value_n of_o what_o the_o person_n be_v use_v to_o take_v in_o a_o cordial_a vehicle_n as_o spirit_n of_o wine_n brandy_n or_o the_o like_a because_o such_o hot_a spirituous_a vehicles_n do_v as_o have_v be_v show_v immediate_o give_v some_o comfort_n by_o actuate_a and_o warm_v our_o spirit_n till_o the_o opium_n come_v to_o operate_v which_o will_v not_o be_v long_o because_o it_o be_v in_o a_o liquid_a form_n if_o you_o find_v the_o person_n sink_v notwithstanding_o he_o may_v be_v keep_v up_o by_o repeat_v the_o brandy_n or_o cordial_n without_o any_o opium_n in_o it_o till_o the_o opiate_n operate_v which_o will_v certain_o by_o god_n help_n set_v he_o right_n in_o case_n it_o do_v but_o begin_v to_o operate_v before_o he_o be_v dead_a see_v the_o philos._n transact_v for_o june_n july_n august_n 1696._o note_v that_o it_o be_v a_o very_a false_a imagination_n that_o author_n have_v of_o the_o turk_n capacity_n by_o nature_n climate_n or_o the_o like_a to_o take_v more_o opium_n or_o in_o great_a quantity_n than_o we_o may_v but_o that_o they_o make_v more_o use_n of_o it_o and_o by_o that_o mean_n come_v to_o take_v 2_o or_o 3_o dram_fw-la a_o day_n for_o they_o begin_v with_o such_o small_a quantity_n as_o we_o common_o give_v till_o by_o a_o long_a custom_n of_o take_v it_o they_o come_v to_o take_v the_o say_a quantity_n which_o be_v but_o small_a in_o comparison_n of_o what_o several_a english_a people_n that_o have_v be_v use_v to_o it_o do_v or_o have_v take_v as_o i_o can_v name_v several_a to_o you_o if_o i_o have_v not_o reason_n to_o the_o contrary_a however_o i_o be_o at_o liberty_n to_o tell_v you_o the_o quantity_n though_o i_o must_v forbear_v name_v the_o person_n some_o have_v daily_o take_v 2_o 3_o 4_o 5_o 6_o dram_fw-la nay_o i_o have_v hear_v of_o some_o that_o have_v take_v a_o ounce_n a_o day_n and_o of_o one_o that_o take_v two_o ounce_n whereas_o the_o learned_a and_o curious_a dr._n edward_n smith_n can_v find_v none_o about_o smyrna_n who_o take_v above_o 3_o dram_fw-la a_o day_n all_o this_o be_v most_o agreeable_a to_o reason_n and_o the_o whole_a current_n of_o my_o discourse_n viz._n that_o it_o can_v be_v better_o bear_v in_o cold_a than_o hot_a wether_n and_o consequent_o in_o cold_a than_o hot_a climate_n by_o firm_a flesh_v person_n than_o such_o as_o have_v soft_a and_o flaccid_a flesh_n as_o the_o southern_a people_n have_v in_o comparison_n of_o the_o northern_a and_o such_o as_o inhabit_v cold_a country_n therefore_o you_o may_v be_v sure_a that_o such_o as_o inquire_v into_o the_o cause_n why_o the_o turk_n and_o other_o eastern_a people_n can_v take_v great_a quantity_n than_o we_o can_v seek_v for_o the_o reason_n of_o thing_n before_o they_o know_v the_o fact_n nay_o when_o the_o fact_n be_v quite_o contrary_a to_o what_o they_o build_v upon_o we_o may_v as_o well_o expect_v edify_v discourse_n from_o they_o that_o inquire_v why_o fire_n be_v cold_a water_n dry_a and_o the_o like_a as_o from_o such_o as_o suppose_v thing_n contrary_a to_o true_a and_o sensible_a experience_n chap._n xxix_o some_o general_a rule_n caution_n &c_n &c_n concern_v the_o use_n of_o opium_n though_o there_o be_v hardly_o any_o rule_n caution_n or_o thing_n worthy_a of_o observation_n concern_v the_o use_n of_o opium_n but_o what_o be_v imply_v or_o easy_o inferable_a from_o what_o have_v be_v say_v nor_o now_o that_o the_o true_a nature_n of_o opium_n be_v discover_v can_v there_o be_v such_o fear_n and_o jealoufy_v which_o multiply_v caution_n concern_v the_o administration_n thereof_o for_o every_o one_o may_v now_o easy_o see_v wherein_o its_o danger_n and_o benefit_n lie_v yet_o because_o a_o chapter_n of_o rule_n and_o caution_n may_v be_v expect_v as_o be_v usual_a and_o to_o have_v a_o single_a view_n of_o such_o as_o lie_v more_o scatter_v and_o not_o so_o ready_o find_v in_o the_o body_n of_o the_o book_n i_o will_v to_o introduce_v the_o use_n of_o opium_n with_o more_o clearness_n and_o perfect_a security_n give_v you_o a_o collection_n of_o general_a rule_n and_o caution_n concern_v its_o use_n whereof_o some_o be_v mention_v and_o most_o inferable_a from_o the_o premise_n i._o as_o to_o its_o substance_n 1._o it_o shall_v be_v always_o give_v free_v from_o its_o resinous_n part_n if_o you_o can_v get_v such_o a_o preparation_n 2._o it_o be_v also_o neat_a and_o convenient_a that_o it_o shall_v be_v free_v from_o all_o its_o earth_n and_o dress_n 3._o never_o give_v opium_n but_o either_o so_o prepare_v or_o with_o its_o rosin_n so_o subdue_v segregated_a or_o alter_v as_o i_o have_v show_v in_o the_o safe_a preparation_n thereof_o iâ—_n follow_v that_o 4._o crude_a opium_n and_o extract_v make_v in_o sulphureous_a spirit_n be_v utter_o to_o be_v reject_v 5._o never_o give_v it_o mix_v or_o join_v with_o resinous_a thing_n as_o have_v be_v intimate_v 6._o never_o mix_v or_o join_v it_o with_o other_o opiate_n 1._o because_o none_o of_o they_o be_v so_o good_a 2._o because_o they_o be_v not_o so_o well_o know_v 3._o because_o it_o make_v the_o do_v more_o uncertain_a 4._o because_o those_o other_o opiate_n be_v use_v unprepared_a 7._o pil._n e_o styrace_n because_o make_v of_o resinous_a opium_n join_v with_o resinous_a thing_n as_o styrax_fw-la calam_fw-la and_o olibanum_n be_v a_o insufferable_a preparation_n though_o commend_v and_o therefore_o have_v frequent_a ill_a effect_n to_o my_o knowledge_n 8._o pil._n â—_o cynoglossâ_fw-la be_v such_o another_o have_v two_o opiate_n in_o it_o beside_o opium_n extract_v out_o of_o spirit_n of_o wine_n which_o be_v far_o worse_a than_o crude_a opium_n though_o by_o the_o way_n of_o eminence_n call_v opium_n prepare_v in_o our_o dispensatory_a styrax_n calam_fw-la and_o olibanum_n which_o be_v resinous_a 9_o laudan_n lond._n be_v also_o a_o ill_a preparation_n as_o have_v the_o
benefit_n as_o in_o many_o of_o the_o former_a to_o be_v short_a it_o be_v good_a and_o useful_a in_o all_o pain_n and_o grievous_a sensation_n 1._o eecept_n all_o such_o as_o tend_v to_o the_o speedy_a and_o timely_a benefit_n of_o person_n as_o those_o in_a woman_n labour_n grievance_n at_o stomach_n that_o cause_n vomit_v upon_o over-repletion_n or_o by_o reason_n of_o somewhat_o that_o grieve_v and_o be_v not_o convenient_a to_o stay_v at_o stomach_n or_o irritation_n to_o expectorate_v when_o much_o want_v as_o happen_v sometime_o in_o vomicas_fw-la pleurisy_n peripneumonias_n etc._n etc._n or_o such_o as_o irritate_fw-la and_o solicit_v to_o make_v water_n go_v to_o stool_n etc._n etc._n when_o evacuation_n of_o urine_n ordure_n ill_a humour_n etc._n etc._n be_v requisite_a 2._o except_o when_o grievous_a sensation_n be_v necessary_a call_n or_o intimation_n for_o supply_v refreshment_n etc._n etc._n as_o hunger_n thirst_v etc._n etc._n which_o shall_v be_v take_v off_o only_o by_o the_o pleasure_n of_o good_a meat_n and_o drink_v lest_o nature_n be_v defraud_v where_o you_o may_v observe_v a_o inconvenience_n that_o may_v happen_v by_o the_o frequent_a use_n of_o opium_n take_v away_o appetite_n without_o nutriment_n though_o this_o be_v much_o compensated_a by_o the_o relaxation_n and_o recruit_v that_o opiate_n give_v and_o their_o moderate_v the_o expense_n of_o spirit_n by_o take_v of_o contraction_n and_o may_v more_o if_o not_o whole_o by_o a_o regular_a and_o constant_a way_n of_o eat_v and_o drink_v temperate_o at_o usual_a time_n though_o the_o hunger_n may_v not_o by_o reason_n of_o the_o opiate_n be_v so_o great_a as_o at_o other_o time_n i._o the_o form_n be_v indifferent_a and_o to_o be_v order_v only_o according_a to_o the_o general_a rule_n remember_v that_o the_o liquid_a be_v best_a for_o speed_n ii_o the_o dose_n must_v be_v proportion_v to_o the_o pain_n or_o grievous_a sensation_n and_o always_o rather_o more_o than_o when_o there_o be_v no_o pain_n because_o its_o contraction_n oppose_v the_o relaxation_n to_o be_v induce_v by_o the_o opiate_n observe_v this_o method_n first_o give_v a_o good_a do_v then_o stay_v about_o 2_o or_o 3_o hour_n and_o if_o the_o pain_n be_v not_o at_o all_o lessen_v you_o may_v safe_o then_o give_v half_a the_o quantity_n again_o and_o afterward_o about_o a_o three_o part_n of_o the_o do_v every_o 2_o or_o 3_o hour_n till_o it_o begin_v to_o abate_v but_o upon_o the_o least_o sensible_a abatement_n you_o must_v forbear_v to_o give_v any_o more_o because_o that_o which_o do_v in_o some_o measure_n abate_v the_o pain_n do_v in_o the_o same_o proportion_n abate_v the_o contraction_n and_o consequent_o it_o have_v less_o to_o contest_v with_o therefore_o will_v be_v sure_a to_o conquer_v it_o for_o the_o same_o power_n that_o can_v subdue_v ten_o in_o some_o measure_n will_v subdue_v nine_o in_o a_o great_a measure_n and_o eight_o more_o easy_o than_o nine_o etc._n etc._n till_o the_o pain_n quite_o cease_v whereas_o if_o you_o add_v more_o power_n to_o the_o opiate_n it_o may_v be_v too_o much_o especial_o when_o the_o pain_n be_v thereby_o conquer_v and_o that_o it_o have_v no_o contraction_n to_o contest_v with_o for_o than_o it_o will_v be_v as_o if_o a_o great_a do_v be_v give_v to_o one_o that_o have_v no_o pain_n but_o if_o the_o pain_n increase_v again_o you_o may_v safe_o repeat_v the_o half_n do_v etc._n etc._n every_o 2_o or_o 3_o hour_n till_o it_o again_o begin_v to_o abate_v and_o no_o long_o which_o you_o have_v better_o observe_v to_o do_v as_o soon_o as_o ever_o the_o pain_n begin_v to_o return_v because_o it_o take_v some_o time_n to_o operate_v it_o sollow_v then_o that_o the_o liquid_a form_n be_v most_o convenient_a in_o this_o case_n for_o expedition_n my_o particular_a and_o effectual_a manner_n of_o use_v it_o in_o the_o gout_n will_v be_v somewhat_o too_o redious_a to_o be_v set_v down_o therefore_o since_o it_o may_v be_v obvious_a enough_o to_o the_o sagacious_a that_o consider_v what_o have_v be_v say_v and_o the_o nature_n of_o the_o distemper_n i_o will_v pass_v that_o by_o at_o this_o time_n iii_o the_o vehicle_n in_o cold_a stomach_n and_o constitution_n may_v be_v a_o glass_n of_o wine_n or_o some_o temperate_a cordial_n but_o in_o hot_a case_n or_o where_o a_o fever_n be_v fear_v emulsion_n milk_n and_o water_n or_o water_n alone_o or_o other_o acceptable_a cool_a thing_n or_o such_o as_o be_v direct_v in_o the_o case_n of_o procure_v relaxation_n in_o the_o last_o chapter_n because_o it_o be_v relaxation_n that_o take_v away_o pain_n as_o have_v be_v mechanical_o demonstrate_v but_o heâ—e_v there_o be_v no_o need_n of_o be_v scrupulous_a as_o to_o the_o vehicle_n unless_o it_o be_v in_o respect_n of_o heat_n and_o cold_a as_o the_o case_n happen_v iv_o the_o time_n may_v be_v any_o hour_n as_o the_o case_n require_v only_o remember_v that_o sleep_n conduce_v much_o to_o relaxation_n and_o therefore_o to_o the_o take_v away_o of_o pain_n v._o the_o regimen_n to_o be_v use_v in_o the_o case_n of_o relax_v in_o the_o last_o chapter_n will_v suffice_v but_o it_o be_v convenient_a as_o be_v say_v to_o regard_v the_o stomach_n and_o hot_a and_o cold_a constitution_n especial_o where_o there_o be_v any_o fear_n of_o fever_n by_o give_v cool_a liquid_n as_o emulsion_n etc._n etc._n and_o avoid_v hot_a or_o solid_a thing_n especial_o such_o as_o be_v hard_a of_o digestion_n as_o flâ—sh_v fish_n egg_n etc._n etc._n 1._o note_v that_o it_o be_v very_o advisable_v not_o to_o defer_v the_o use_n of_o opiate_n too_o long_o till_o people_n be_v very_o weak_a though_o it_o may_v seem_v that_o they_o will_v hinder_v some_o due_a evacuation_n for_o i_o can_v see_v what_o harm_n a_o refreshment_n by_o they_o may_v do_v any_o more_o than_o by_o sleep_n both_o depend_v upon_o the_o same_o cause_n viz._n relaxation_n it_o be_v true_a that_o by_o reason_n of_o sleep_n or_o a_o opiate_n the_o evacuation_n may_v be_v a_o little_a defer_v what_o then_o will_v any_o man_n deny_v sleep_n for_o that_o reason_n why_o then_o shall_v a_o physician_n deny_v a_o opiate_n to_o cause_v it_o respite_n nature_n and_o enable_v it_o to_o bear_v its_o burden_n or_o engage_v with_o difficulty_n the_o better_a 2._o remember_v always_o that_o sleep_n be_v a_o great_a help_n to_o take_v away_o pain_n and_o so_o be_v all_o thing_n that_o conduce_v to_o relaxation_n or_o pleasant_a diversion_n 3._o use_v means_n in_o pain_n of_o the_o hemorrhoid_v furdament_n or_o intestinum_fw-la rectum_fw-la and_o indeed_o in_o any_o pain_n within_o the_o gut_n unless_o it_o proceed_v from_o a_o looseness_n that_o opiate_n may_v not_o bind_v man_n too_o much_o as_o leâ—itives_n internal_o or_o emollient_a 〈◊〉_d or_o which_o of_o they_o may_v be_v most_o easy_o and_o convenient_o do_v and_o most_o to_o the_o purpose_n chap._n xxxv_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o cause_n sleep_n it_o primary_o cause_n sleep_v by_o relax_v and_o compose_v quiet_v soothe_v please_a and_o lull_v the_o sensitive_a soul_n and_o spirit_n it_o always_o relax_n but_o do_v not_o always_o sufficient_o compose_v or_o quiet_v the_o spirit_n to_o cause_n sleep_n to_o which_o both_o be_v requisite_a secundary_o by_o take_v away_o grievous_a passion_n or_o sensation_n when_o they_o happen_v to_o hinder_v it_o 1._o as_o soporiserous_a it_o be_v of_o incomparable_a use_n in_o all_o troublesome_a watch_n whether_o they_o be_v from_o grievous_a passion_n or_o sensation_n or_o irrequiete_a motion_n of_o the_o spirit_n though_o not_o so_o certain_a in_o this_o last_o case_n as_o in_o the_o former_a and_o therefore_o prove_v sometime_o unsuccessful_a in_o some_o person_n and_o in_o some_o sort_n of_o madness_n as_o the_o merry_a or_o furicus_n though_o it_o be_v effectual_a in_o melancholy_n and_o slow_a manias_fw-la as_o have_v be_v intimate_v for_o bare_a relaxation_n suffice_v in_o the_o two_o first_o case_n where_o sleep_n be_v hinder_v by_o contraction_n which_o it_o never_o fail_v to_o take_v off_o if_o give_v in_o a_o due_a quantity_n as_o have_v be_v direct_v 2._o to_o recruit_v the_o spirit_n as_o when_o people_n be_v tire_v with_o labour_n journey_n disease_n conflict_n of_o nature_n as_o by_o convulsion_n vomit_n purge_n hysteric_a fit_n and_o the_o like_a 3._o to_o relax_v compose_v take_v away_o pain_n moderate_a flux_n that_o depend_v upon_o grievous_a sensation_n or_o irritation_n and_o its_o consequent_a contraction_n or_o from_o motion_n or_o segregation_n of_o humour_n 4._o to_o promote_v flux_n that_o depend_v upon_o relaxation_n as_o perspiration_n sweat_v as_o also_o the_o menses_fw-la and_o lochia_n in_o some_o case_n of_o all_o which_o you_o have_v particular_a chapter_n which_o see_v i._o the_o form_n may_v be_v indifferent_o either_o solid_a or_o liquid_a as_o