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A33733 A physico-medical essay concerning the late frequency of apoplexies together with a general method of their prevention and cure : in a letter to a physician / by William Cole. Cole, William, 1635-1716.; Kimberley, Samuel. 1689 (1689) Wing C5043; ESTC R23720 53,543 201

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introduced and also such a debility may be impressed on the tone of the Brain that they may much more readily invade if the ordinary though at other times innoxious for the most part at least occasions happen to bring these dispositions to effect Now 't is known that the Winter of the year 1683 from which I date my Aera of this frequency of Apoplexies was so intensly cold and that cold of so long continuance that no mans memory living could supply him with a parallel year and there was no need to repair to the Northern Region to make experiments of freezing spirituous liquors in order to find out the extent of this effect of it since which time it may be observed that this distemper has been so rife But since 't is requisite the Assertion should be established as much as posible by due observations it came into my thoughts to examine the London Bills of Mortality which may be presumed to be a standard for all the Kingdom as well as all other places where the same constitution of the Air has happened And though it may be urged that the accounts of diseases in them are taken by persons who are not Judges of those things yet many diseases carrying by their obvious symptoms such evidences of their nature that 't is almost impossible to mistake them and above all Apoplexies as before was suggested if the matter of fact whereof the Searchers are Judges as to the number of those that dye sodainly and 't is great odds those for much the greatest part dye of Apoplexies be cleare as I suppose 't is acknowledged by all I see nothing but it may be brought to establish the Hypothesis Having therefore looked into the general Bills for near Twenty years past I find the account of those that dyed of Apoplexies and sodain death which are there and I conceive may passably enough be reckoned under the same class to stand thus An. Dom. Apop sud 1670 79. 1671 63. 1672 65. 1673 84. 1674 101. 1675 86. 1676 84. 1677 66. 1678 83. 1679 103. 1680 95. 1681 94. 1682 100. 1683 108. 1684 152. 1685 112. 1686 129. 1687 110. From whence I think the probability at least of my Aera may be inferred whatever may be thought of the notions that are brought to give a reason of it For the great increase of number in the year 1684 must evidence that and it seems obviously deducible that as some great and general cause from the constitution of the season must influence such accidents so that assigned from the Coldness may have that energy here since both 't was so remarkable and nothing else appeared either upon my own or any others observation or notion so farr as I have yet learnt fit to stand in competition with it And from comparing the accounts of the subsequent years with those which went before there seems reason enough to suppose that since the indisposition lasted but in somwhat a lower degree though the external occasion have ceased the weakness impressed on the nervosum genus according to what has been before deduced is not yet obliterated And indeed if we take notice of a disease of another denomination in the same papers which by the dreadfulness of its symptoms is almost as evident as the Apoplexy viz. the class of Convulsions we may observe the effect of that impression on the Brain to be so farr from vanishing that it rather seems to be in the increase tho' the symptoms that declare it are altered that class standing thus An. Dom. Convuls 1670 1695. 1671 1650. 1672 1965. 1673 1761. 1674 2256. 1675 1961. 1676 2363. 1677 2357. 1678 2525. 1679 2837. 1680 3055. 1681 3270. 1682 3404. 1683 3235. 1684 3772. 1685 3420. 1686 3731. 1687 3967. So that though the flaceidity impressed on the Brain from that occasion may be in good measure by this time abated and unless the like or some as forcible causes happen again may 't is to be hoped quite cease and I suppose it may be observed that the forementioned frequency of Apoplexies is a late somwhat abated yet it may however have been so disordered in its tone as to make secretions of substances out of the alluent Bloud which carries matter for those of very many sorts which may become so disagreeable to the nervous liquor as necessarily to produce those terrible symptoms which tho' they kill not so immediately yet many times prove as certainly fatal at long running And the great numbers of vertiginous and other nerval indispositions which I presume other Physitians as well as my self usually meet with may very well argue some considerable indisposition impressed on the Brain more of late than formerly which must give a rise to them And indeed if we observe it we may find at least I have that most Feavers of late years and even at this time have been attended with nerval Symptoms as either Tremors or Convulsive motions in the Tendons or else Comatous affects Deliria for the most part slow or some others of this original And the Symptoms mentioned by that most curious observer of the changes of diseases my Learned and Worthy Friend Dr. Sydenham in his Schedula monitoria de novae Febris ingressu to discriminate the Feaver of this new Constitution from those foregoing are obviously those of the Brain or Nerves affected as may be easily collected by those that cast their eye on the History of it he layes down So that the notion is not to be restrained to Apoplexies but ought to be carryed farther to many if not most other nerval indispositions which I conceive may be occasioned by the same general cause For if it be determined to act on the Brain to its weakning as I have endeavoured to demonstrate intense Cold is the constitution of it and its appendices being very much differing in several persons it must follow that diseases of various kinds and denominations may happen according as the organization of either the Brain or the Systema Nervosum which may be possibly concluded to be the whole Body except the liquors and Parenchymata happens to be different in some from what it is in others And indeed the Brain in all persons who have even the most firm constitution of it being yet of too tender a one to resist all impressions made by so powerful a cause as the forementioned disposition of the Air was being so hard to be restored when once injured if that be not fully done easy to be afresh affected even by much less powerful causes of many other kinds which frequently happen upon the various mutations of the Air 't is no wonder that the Bills should be so filled with Convulsions aswell as that other nerval indispositions should now adays so much invade But in relation to the numerousness of Convulsions mentioned as I said in the weekly Bills it being objected that their fatality happens probably most to Children which having been born since that frosty