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A50433 The frequent, but unsuspected progress of pains, inflammations, tumors, apostems, ulcers, cancers, gangrenes, and mortifications internal therein shewing the secret causes and course of many lingering and acute mortal diseases, rarely discerned : with a tract of fontanels or issues and setons / by Everard Maynwaringe, M.D. Maynwaringe, Everard, 1628-1699? 1679 (1679) Wing M1492; ESTC R31211 108,750 246

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pressure here raiseth a fainting pain the Cartilage yielding and giving way to any force But sometimes a pain is planted here not always by any external manifest cause but from internal and preternatural state of the parts and this pain is rarely taken notice of by Physicians and mentioned but by a few practical Authors Now to examine into the cause of pain you must know that this Cartilage is flexible and yielding in its natural condition being of a middle nature between a Bone and a Ligament and therefore may be curvated and bent inward upon a threefold account By Laxation Exsiccation and external depression 1. By Laxation as when too much moisture resides here mollifying and loosning the part from any small occasion the Cartilage may be inflexed and turned inward changing its due position and rectitude and from the like cause Ligaments are sometimes relaxed which renders Junctures ready and apt for dislocation and disjuncture and upon this score the Vertebrae of the Spine have been displaced also the Hip and Ancles 2. By Exsiccation this Cartilage may be distorted and wrested from its posture as sometimes that which was straight green and pliable by drying and shrinking becomes crooked bent and drawn aside So this Cartilage that was a Grisle tender and pliable sometimes becomes dry hard and bony and fixed upon distortion or writhing as not returning to its rectitude or straightness and distance from the subjacent parts over which and for whose guard it is placed 3. By external Depression as from a blow or fall any thing too much or too long pressing upon that part may pervert and alter the situation and due posture and those whose business or imploy keeps them bending or pressing forward too much and constant renders them liable to this inconvenience and therefore Students and Clerks that write much pressing upon this part are injured thereby and find it upon age though youth bears it off for a time Now since this Cartilage is thus exposed to depression and bending inward and thereby the tender parts subjacent to be pressed upon and molested the cause of pain and manner how is made evident and which most commonly is felt after eating and upon a full stomach when the parts are dilated and swelling up to this Cartilage And farther as all parts of the Body in several persons do vary and differ much in figure position magnitude and distance so thereby some are more liable and apt for this pain than others although subject to the same external procuring or internal antecedent causes And so I dismiss this particular pain and pressure and must take cognizance briefly of that which is more general upon the whole Breast The Thorax or Breast suffers by compression or constriction whereby a general obtuse pain of angustness is perceived and that chiefly upon inspiration and drawing in of the breath and why now more than at another time is because the inspired air fills and distends the Breast which makes opposition to or resists the compressing causes Now the cause of angustness or coarctation is from the Genus nervosum that gives motion to the Muscles and other parts of the Breast which Nerves sometimes are impedited and contracted that their functions are not freely executed and therefore to this Symptom of compression is commonly adjoyned shortness or difficulty of breathing upon the same score and sometimes spasms or convulsive motions And this complaint of straitness or contraction of the Breast does frequently happen to scorbutic persons whose nervous juyce being degenerate and tainted their Organ or Vessels perform not their office duly as they ought in giving the full motion and extension or every part for this nervous liquor being fed and supplied from the mass of blood which is scorbutic feculent and depauperated in spirit that also which is extracted thence must be answerable and of a degenerate nature so then this nervous juyce which should be vegete noble and spirituous for putting the motive faculties into action with vigor and briskness is become dispirited flat and depraved and the Organs acted thereby move heavily and irregularly so that upon inspiration or filling the Breast with Air the parts do not readily give way by expansion to let in hence the Patient feels himself girt or strait-laced It remains now in the last place that we finish this second division in examining and searching into the nature and causes of those pains that more peculiarly and eminently afflict the Heart The Heart being a noble or the noblest and principal part is as the Sun of the Microcosm whose irradiating lustre and beams of vital heat enlivens and refresheth all the regions and parts thereof the Eclipses storms and clouds then that happen as the consequents of its distempers and sufferings must needs be eminent and remarkable This supreme Organ that bears the government of vitality is so generally concerned in all diseases and discomposures of the Body that few there are but the Heart is made sensible thereby and gives notice thereof by variation of the Pulse as a sigrial from thence And not only distempers of the Body or the defect and decay of some particular member or faculty does affect the Heart but also the disorders and passions of the Mind have influence thereon that from thence the Heart akes beats or suffers pain and restless disturbance hence it is that grief anger fear desire c. Changeth the regular motion of the Heart and the Pulse alters as a token and manifest character of its sufferings Now the Heart is made thus sensible of the Bodies infirmities and preternatural mutations from the vital government that is planted here having commerce and communication with every member from the circulating afflux and reflux of the crimson vital stream continually transmitted through this Organ which thereby is affected well or ill as the blood is better or worse in the current and quality thereof And the Heart is also affected from the mind for as much as the Soul exerciseth her power more eminently here and if a particular part may bee assigned this may be said to be the seat or Throne of Regality The Heart being of a solid fibrous flesh the pain thereof is obtuse not so accurately perceptible so acute and sharp as those of the nervous parts notwithstanding the effects and consequents thereof are impressed upon the whole Body and each member is impaired in its vivacity and vigor and although this Heart pain by the nature and substance of the Organ is not so great commonly and perceptible as that of some other parts yet when this pain does arise to some degree a Syncope seizeth the Patient a deprivation or cessation of life for a time that what it wants as to sense is doubled in the consequents as threatning and endangering the life so that extremity of pain is not perceived here because sense decays as the cause of pain increaseth The Heart is molested and suffers pain these several ways by extension
his right aims at the morbific cause Hence ariseth all the inventions of cooling and so frequently used in most cases repeated Phlebotomies Ptisans Juleps Emulsions cooling Apozems Embrocations Liniments c. which make the great clutter of Pots and Glasses about the sick and nothing more advantageous to the Apothecary than trifling away the time thus with a number of these hazardous but many times and too often pernicious Medicines This mode of Practice and these devices for cooling feaverish bodies I suppose are taken up in imitation of Galen a famous Master of this Art who appoints exhaustion of blood by Phlebotomy ad animi deliquium until the Patient faints and large draughts of cold water until the Patient turns pale shakes or quivers and the whole body cooled And an Author of our time in his Writings de Febribus appoints the casements to be set open to cool the sick upon what design I know not except to fan the house lest the heat of the Feaver should fire the chamber And a late Author of great Fame in his Works de Febribus supposing Feavers to arise à sulphure accenso exaltato from a sulphurous deflagration of the blood prosecutes upon the indication of refrigerating and quenching this fire by cooling Liquors and for incouragement herein gives an example I suppose his own Patient of a young man about twenty years old that by immoderate drinking of Wine fell into a Feaver with thirst and insignal burning about the Heart who after Phlebotomy and plentiful drinking of water aquae fontanae ingentem quantitatem ebibit the Authors words he recovered The success was good and I may say wonderful but whether from the means or Providence judge you but I shall not imitate the Practice lest ten dye for one that lives but this learned Doctor hath highly deserved in some other parts of his Writings and therefore I tread softly Now to consider all this in gross for brevity sake and apply it to our purpose in hand these ways truly are very probable not rational to cool a feaverish hot sick man and to make him in a short time stone-cold and the probability thereof upon good ground does appear thus First Upon the account of this latent Series and progress Inflammations Tumors c. ushered in by pain more frequently than discerned as already proved this refrigerating course the insisting upon or intermixing these cooling Medicines now and then to quench a preternatural heat is destructive at best a great delay and impediment in the Cure and this is the common way of Practice which needs no farther confirmation but a review Secondly In all other cases and from what cause soever a Feaver doth arise this juleping and cooling mode of Practice is dangerous more or less as the case is in it self but in no wise advantageous making acute diseases to commute and terminate in chronic and chronic or lingering diseases to hold on their course and become more contumacious To prove the first we shall compare that series and commutation of diseases with the designment and nature of these cooling Medicines and by that you shall see what probability and season there is to expect from thence any good effect but rather the contrary promoting of mischief begun and setting forward those diseases Whatever causeth pain whether it be obstruction in the part or oppression by indigested or degenerate incongruous matter by wind and flatulency by any exotic generation as worms stones c. any Tumor or Apostem breeding Inflammation or Vlcer planted c. these cooling and cold inventions touch not the disease except to do mischief and exasperate and remove no morbific cause for the nature of these causes and diseases requires Aperitives Abstersives Catharticks Discussives Diaphoreticks Dissolvents Sarcoticks c. pro re nata each case requiring some or more Medicaments of these Operations But these Coolers è contrà stand in opposition and act repugnant to these properties and consequently to the Cures of those infirmities by obstructing of Ductures and Pores incrassating what should be attenuated coagulating what should be kept fluid condensing what ought to be rarified and discussed fixing and retaining what should be moved and sent off impeding transpiration but promoting putrefaction generally they check and damp the power of Nature endeavouring to extricate and quit her self from those incumbrances and growing evils that assault and beset her To make good the second part that in what other case soever a Feaver or vehement heat shall arise with ebullition of the blood and preternatural fermentation cooling Medicines are very prejudicial in many cases mortal for whether it be a pestilential or other maligne Miasm seminary or taint or other impurity and feculency of the blood that Nature intends by this febrile disturbance and irritation to throw off and separate which Nature sometimes without help does perform and makes a good Crisis but these Coolers act counter to and prevent Natures good work checking the fermentation and thereby hindering the separation of any degenerated or noxious admixture And the reason of these ill consequents from Coolers does mainly lye here for as the stomach doth preside over and hath great influence upon the other faculties and subsequent digestions whose briskness and vigorous performance depend much thereon so likewise whatever subverts the tone of the Stomach and flats the acuteness of this principal part and prime office of digestion injures allays and abates the energy of the rest impedes the fermentation of the blood for depuration in such cases as also for conservation and. supply in the constant daily work And although the Patient escapes this Feaver and comes off with life yet by this male Practice they fall into Dropsies Scurvies Jaundies and cachectic foul habits of body an obstructed or tumified Spleen Liver Mesentery c. Or it breaks out upon the Skin and some eruption or cutany defedation will appear in time or it settles in some Limb and disables the part And it is but reasonable to expect that Patients thus cured should soon be Patients again upon the old account the relicts of the former sickness for that morbific matter and cause of Feaver being retained by checking and cooling the febrile fermentation and not observing Hippoc. advice Quò natura vergit this morbous impurity and foulness must precipitate and settle somewhere and then you may well imagine it will make some appearance or alteration in time upon some part or other and then an after-game is to be played for not having its due fermentation secretion and pass-port formerly when it did turgere and was upon the flight only wanted the Physician 's direction and guidance hinted by Hippoc. 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉 Aphor. 21. Sect. 1. Now a hole in the skin perhaps is thought on an Issue for a tedious and troublesom vent to discharge the matter which a good laudable course in due time might have prevented And thus or by this means the Patient comes into the Physicians
constriction obstruction inflammation or intemperate heat Imposthumation by erosion by exotic generation 1. The Heart is pained by extension from a sudden ebullition and turgid fermentation of the blood raised by passion or otherwise whereby the Vessels are suddenly forced upon distension to receive and transmit the inundation and swelling current of the blood and from hence pain and trouble ariseth at the Heart 2. By constriction the Heart is pained and that from external and internal cause externally from the Pericardium compressing whereby the Heart is denied the full liberty of its Diastole or expansion and this may arise upon a double account either from the Pericardium being too replete and full or too much exhausted and empty You must understand therefore that this Pericardium or Capsula cordis is a Membrane designed by Nature to involve and inclose the Heart for its defence as also being a moist Bath to irrigate and keep it souple containing a Serum or water and this Membrane should extend and be enlarged according to the motions of the Heart being greater or less now when this water does abound filling the cavity of this inclosure the Heart thereby is prohibited its full expansion and è contrà when this water is too much wasted and dryed up the Pericardium cleaves to the Heart and impedes its pulsific motion thus either plenitude or vacuity begets anxiety and trouble at the Heart Internal cause of constriction is when the Heart it self is seized with a Tabes or vehement exsiccation and the fibres so contracted that it hath no capacity or less for dilatation and permission of the transient blood 3. Obstruction causeth pain and trouble at Heart when the free current of the blood is impeded from within due Vessels and this is procured sometimes from a perturbation of the movent spirits and sometimes from an indisposition of the impulsed blood First from a sudden and violent recurrence of Spirits from other parts and tumultuous confluence at the Heart whereby the circulation is checkt and the blood stopt in the Ventricles causing a suffocation for a time and this happens upon vehement passions and consternations of the mind Secondly From an inhability and incapacity of the blood being gross concreted or grumous that it hardly or with difficulty passeth through this Organ causing thereby an obtuse pain oppression or heaviness at the region of the Heart and sometimes a Lipothymy or Syncope fainting or swooning 4. By Inflammation or intemperate heat the Heart is pained as in most Feavers where intensness of heat is accompanied and this heat continuing does exsiccate and contract the heart and brings a Tabes or Consumption upon the whole Body 5. By Imposthumation the Heart is pained sometimes as also by other Tumors there bred Which by dissection hath appeared after death 6. By Erosion or Vlceration sometimes the Heart is pained and suffers by continual palpitation 7. By exotic Generations and strange productions the Heart sometimes is pained as when worms stones or bony substance is bred in the Parenchyma of ' the Heart which hath been found there upon dissection after death and to these diseases and such as most of the forementioned the Symptom of Palpitation does necessarily belong shewing the continual molestation and trouble the Heart lyes under who endeavors to acquit and extricate it self by laborious lofty and strong pulsations Pains in the Abdomen or lower Region of the Body NOW we have done with those pains incident to the middle Cavity namely the Thorax or Breast I come in the next place and by the order proposed to the lower Region called the Abdomen or Belly containing the Stomach Liver Spleen Kidneys c. And here first as the principal member we shall inquire into pains belonging to the Stomach or Ventricle being the great Office and Laboratory to prepare Aliment to supply and maintain the whole Body therefore if this part be pained and out of order all the rest must needs fare the worse for it every part having a concern from hence Pains of the Stomach are various both in respect of their causes and also from the different parts of the Ventricle where they do infest and those are three the upper Orifice called Os Ventriculi the lower Orifice called Pylorus and the whole cavity of the Stomach The upper Orifice or mouth of the Stomach is subject to great pain as being very tender and sensible in regard it is very nervous and this pain is the more eminent and remarkable for that commonly two principal parts are hereby affected and drawn into consent the Brain and the Heart the former by the Nerves of the sixth conjugation derived from the Brain whose ramifications are wreathing or twining about this Orifice and therefore from hence Head-aches Vertigoes and Epilepsies do often arise The Heart also is affected both in respect of vicinity as near adjoyning to this Orifice and also for that the same pair of Nerves doth serve both the Heart and Stomach whereby of necessity there must be a communication of pain and therefore it is that this pain in extremity causeth Fainting and Swooning and hence it is that this pain by a peculiar distinguishing title is called Cardialgia and also for that the ancient Greeks called the mouth of the stomach 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉 As for the causes of this Cardialgia or stomach-pain sometimes they are sharp acrid and hot biting humors fluctuating and rising up to the Orifice of the stomach where they cause an eroding or gnawing pain and sometimes a scalding or heat there and this vulgarly is called the Heart burning Sometimes flatulency and wind causeth this pain by way of distension and a swelling fulness and the Orifice is constringed and shut up so as denying vent in this case the Patient labours and strains to belch but cannot unlock or loosen the Orifice of the stomach but so soon as the Orifice does slacken and give way the wind breaks forth and ease followeth Sometimes Worms do cause this pain having gotten up to the mouth of the Ventricle where they gnaw and bite Sometimes churlish and deleterious or ill prepared Physick or discordant food having such properties as may irritate and provoke this tender part or food received in too great a quantity above what the stomach is able to master and digest then it riseth up to the mouth of the stomach causing oppression and pain there until it be discharged upwards or downwards by the strength of Nature or the assistance of Art Besides this Cardialgia there is also another sort of pain that afflicts the mouth of the stomach and that is Singultus a Hicket or Hickop and although the whole Ventricle be molested therewith yet the chief pain or trouble is at the Orifice or mouth of the stomach This Hickop is a convulsive motion of the stomach thereby causing pain The general causes assigned by Hippocrates are two repletion and inanition under repletion is comprehended whatever humor or vapor is in the
extuberance is out of the Veins that is when the extravasated blood is lodged between the mouths or terminations of the Veins and the covering coats In the former case and when the external Haemorrhoid Veins be so affected Phlebotomy may alleviate make a revulsion and draw away the plenitude but in the latter it gives no relief for the extravasated blood will not return into its canal or pipe again and besides it soon coagulates and putrifies out of the Vessels the proper place and then suppuration is to be promoted the Apostem to be broken after that abstersion and healing to be designed and endeavoured And here you may discern the difference between these two Haemorrhoid painful swellings that the first kind does abate and retire of its own accord sometimes Nature retracting and turning the current of blood to some other part at least it sooner yields to means and is more easily remedied but the latter will not revert nor is easily cured but proceeds to Apostemation and after breaking sends forth corrupt and bloody matter From hence you may perceive that as there are many sorts of Haemorrhoids so many questions might here be started and much more to be said concerning them to compleat the Discourse thereof as why the Hemorrhoids should swell and not bleed sometimes Why they are painful and sometimes not Why they appear and pass away without injury sometimes What difference between an Inflation and Inflammation of the Haemorrhoids c. But to inlarge hereon and give full satisfaction would swell this Work beyond intention and our limits set at this time Pains of the Spleen THE Spleen being a principal part and of great use in the Body is also subject to disturbance and great pain This member is seated in the left Hypochonder over against the Liver below the Diaphragma and under the short Ribs hanging downwards in figure like an Ox-tongue inclining rather to the back-parts and near the left Kidney To pass over the different Opinions amongst the ancient and modern Authors concerning the office of this Organ we shall concur with those that assign the use of this member for a depuration of the blood transmitted from the Heart to receive a farther elaboration there that the whole mass of blood may be purified and kept in a due state From whence it comes to pass that when the Spleen is injured out of order or decayed and performs not this office aright the blood becomes foul and many diseases arise from thence which causeth much alteration in the body for with the Spleen do many parts consent and well or ill as that is in a good or bad condition The Brain though remotely seated is much affected from hence causing sometimes Epileptic fits Vertigoes Head-aches mad Melancholy and many other Symptoms which Hippocrates hath observed 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉 The Heart also from a tumified or obstructed Spleen is drawn into consent causing palpitations and oppressions Hence also difficulty of breathing from a swelled big Spleen hindering the free motion of the Diaphragma The Liver also seldom stands firm if the Spleen be diseased And the Pancreas for the most part incurs prejudice being obstructed or scirrhous from an ill affected Spleen Hence it is that the Spleen challengeth a great share in the production of divers Cachexies or ill habits of body Dropsies Scorbute black Jaundice Haemorrhoids Cancers c. of which I might give you many examples but I shall recite one only and that very eminent plainly shewing that the rise thereof and dependence is sometimes from the Spleen In the year 1658. a Cheshire Woman named Elizabeth Swaine a Farmers Wife aged 39 years came to me at Chester where I then practised she living about a dozen miles off her complaint was of pain hardness and Tumor of the Spleen before which happened she had a tertian Ague for some time but after that had left her the left side began to swell and pain upon the region of the Spleen this increasing and when she came to me the Tumor was raised very high and the compass of a penny-loaf being very hard and scirrhous not yielding when it was pressed with a finger Her desire was to be under my care and I was willing to undertake the Cure but she not having brought conveniencies with her to stay would go home and return speedily with such necessaries as she should want but came not again until three months after and then not only the left Hypochonder but the Abdomen her whole belly was tumified and extended as big as if she were ready to be delivered of a child so that the Tumor of the Spleen was then hid the whole belly being equally raised up to it by a Dropsie Ascites This neglect of hers and thereby rendering the Cure much more difficult and uncertain made me to refuse medling with her since by her folly she had lost the opportunity for I was doubtful and feared that the Spleen by that time was become scirrhous and the Tumor not to be discussed or otherwise decayed and putrified as not be restored but she having a Sister living in that City who had been my Patient before upon both their importunate intreaties though I would give little incouragement I unwillingly did put her into a course of Physick but after I began I endeavoured the best I could for her which was as followeth First I appointed a Preparative to be given which was this R. Radie. utriusque bugloss gram cichor apii ana ℥ j. polypod quercin ʒ vi cort cappar median fraxin liquirit ana ℥ ss herb scolopend ling. cervin chamaed ana M.j. Tamarisc Mss sem foenic. dulc ʒ iii. passular maj exacinat M.j. Coq in aq vin alb ad lib. ii colat ℥ iv adde syr de pomis magistral ℥ j. rosar solut ℥ ss tart vitriolat ℈ ss Misce pro dos After that I ordered Leeches to be applied to the Haemorrhoids and much watry blood came away and she found her self something better Then I appointed a purging Apozem for four doses and it was this R. Rad. filicis mar cort cappar polypod ireos nostr liquirit ana ℥ j. herb scolopend M.j. cuscut tamarisc ana M. ss sem alkekeng foenic. dulc anaʒ iii. stor bugloss p. j. Coq in aq vin alb ad lib. jss colat infund sennae opt mund ℥ jss epithymi ℥ j. agar troch ℥ ss rhabarb opt ʒ iii. macis caryophyll ana ℈ ii calam aromat schoenanth ana ℈ j. Fiat colat pro 4 dos addendo unicuique dosi syr rosar solut ℥ j. aq cinnam ʒ ss tart vitriolat ℈ ss Which being taken the distension of her belly began to abate After the Apozem I gave her a Chalybeate Wine for four days mornings and at four a clock after noon with exercise and at nights three aperitive Pills not purging The Chalybeat Wine was this R. Cort. rad cappar polypod ireos nostr liquirit ana ℥ ii herb scolopend cuscut tamarisc ana M.j. chalyb.
Liver BEfore I inquire into the nature and causes of these pains it will be necessary to let you know the office and use of this member its situation figure and vessels for hereby the disease upon which pains depend will be more manifest and apparent as also such parts as suffer by vicinity connexion and consent from hence To enumerate the various Opinions that have been held by Learned men in all Ages concerning the office of this member would be too tedious therefore I shall only mention what latter discoveries have proved most rational from the motion of the Chyle and Blood which is this That the Liver primarily is appointed to receive the blood coming from the Heart to give it a farther digestion and depuration by separating the bilious matter and secondarily by embracing the Ventricle to cherish and promote the stomachs digestion or chylification for which purposes this member is fitly seated formed and furnished with vessels to import and export The Liver is placed in the right Hypochonder under the Diaphragma covered in part by the short Ribs and covering the upper and forepart of the Ventricle and for firmness of situation it is fastned by three Ligaments to the Abdomen to the Cartilage ensiformis and to the Diaphragma The figure of this member upon the superior part is convex or round the better to give way to the motion of the Diaphragma but the under side is concave or hollow fitly to apply to the extension of the Ventricle As for magnitude it is various in divers persons greater and less and also different in the same persons in health and sickness this member sometimes being wasted and shrunk and sometimes swelled or increased wonderfully big This Organ hath vessels appertaining to it as Veins Arteries and Nerves the two eminent great Veins of mans Body Vena cava and Vena portae having their roots variously dispersed here through the Parenchyma or body of the Liver the trunk of the former rising out of the superior gibbous part the latter from the concave and under-side The Liver being designed for the use aforesaid seated and accommodated after this manner we shall inquire into the impediments and preternatural conditions from whence pain and trouble ariseth for many complain of pain and heaviness in their right side about the short Ribs sometimes more forward sometimes backward sometimes inward and sometimes more outward To what parts these pains belong and the causes from whence they arise is worth our labour to be resolved for sometimes pains of the Liver have erroneously been taken for Pleurisies because the pain hath extended upwards and affected the Thorax by reason of vicinity and sometimes the muscular pains of the Abdomen in the right Hypochonder have been adjudged to be hepatic not rightly discerning the diagnostic signs Diseases which the Liver is most subject to and procuring pain are these Obstruction Adhesion Inflammation Inflation scirrhous Tumors Apostems Vlcers From hence we may understand that as these pains are various in their causes so are they dissimilar and unlike in the sense of feeling and differently seated Obstructions that impede and injure the office of the Liver and producing pain are frequent and these are either in the outmost gibbous part and do belong to the trunk of the Vena cava or else in the hollow inferior part and the Vena portae is concerned herein or else the obstructions are fixed in the body of the Liver and then the small ramifications of either or both Veins are affected Hence it is that this member is most frequently infested with obstructions because it is stored with so many vessels as none more But besides these obstructions of the Vessels there are also obstructions in the Parenchyma or substance of this Organ that is when the small Meatus or Pores are shut up that ventilation and transpiration is denied hence it is that this member sometimes is preternaturally extended and increased in magnitude through all its dimensions for having a continual supply of additional matter and not duly expended the part of necessity must be augmented and inlarged And it is observed by some that those have the greatest Livers that are of a colder temperature and such as are great eaters of this Cornelius Gemma gives an example of an Old woman that could not forbear eating and drinking scarce a moment but with great trouble and anguish and being opened after her death her Liver was found to be wonderfully big Signals declaring the Liver to be obstructed are a heaviness fulness or an obtuse pain in the right Hypochonder and chiefly after meat or exercise and upon more than ordinary motion the face is apt to be high-coloured the hands to look red and the breath to be short and they are apt to be feaverish upon small occasions but upon rest and ease commonly they are inclined to be pale Causes from whence these obstructions arise and do depend are first such as remotely dispose as a plentiful and bad Diet or a gross feeding upon such meats as are difficult to be digested and distributed what those are you will find in the Preservation of Health c. also a thick unwholesom Air to be without exercise and to indulge sleep too much which over-clogs the body makes a Plethory and fulness whereby the circulation is retarded laying the foundation and an aptness for obstructions in general Secondly and more immediately from a viscidity and grossness of the blood rendring it influid slow of motion and apt to stop in the vessels and this is generated in the Liver from its distemper debility and decay of the faculty or is transmitted from other parts and brought in from the antecedent causes aforesaid to which we may add angustness of the vessels in some persons disposing to this inconvenience Obstructions of the Liver are carefully to be lookt after and removed because they introduce many other diseases as Jaundice Dropsies Feavers Inflammations scirrhous Tumors c. Adhesion or Coalescence sometimes is the cause of pain in the right Hypochonder as when the Liver sticketh to or groweth together with the Peritonaeum And this may happen from too much and constant lying on the right side or by the magnitude of the Liver extending to the Peritonaeum whether tumified preternaturally or increased by a natural nutrition and growth Now pain ariseth hence the Membrane that invests and covers the Liver being very sensible as all Membranes are that cleaving to the Peritonaeum is disturbed and strained by motion or shaking of the body or by lying on the contrary side the weight of the Liver endeavouring a separation Inflammation sometimes seizeth the Liver and causeth great pain and this commonly proceeds from or is the consequent of obstructions for the blood being stopt in its current and overflowing especially being more hot and fiery is then apt to inflame the part and this is manifest to sense by heat and tension of the right Hypochonder Inflammation is known from