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fire_n little_a put_v water_n 5,400 5 6.6483 4 true
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ID Title Author Corrected Date of Publication (TCP Date of Publication) STC Words Pages
A71263 Pharmaceutice rationalis: or, The operations of medicines in humane bodies. The second part. With copper plates describing the several parts treated of in this volume. By Tho. Willis, M.D. and Sedley Professor in the University of Oxford.; Pharmaceutice rationalis. Part 2. Willis, Thomas, 1621-1675. 1679 (1679) Wing W2850; ESTC R38952 301,624 203

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purge_v hydragogue_n hydragogue_n 2._o diuretic_n hydragogue_n but_o cathartic_o do_v not_o always_o cure_v a_o ascite_n yea_o oftentime_o exasperate_v it_o and_o if_o they_o be_v long_o continue_v render_v it_o incurable_a hence_o it_o be_v necessary_a to_o have_v recourse_n to_o other_o remedye_n for_o the_o cure_n of_o this_o disease_n wherefore_o let_v we_o next_o inquire_v whether_o diuretic_n do_v here_o profit_v or_o not_o and_o true_o any_o one_o may_v easy_o think_v that_o remedy_n move_v urine_n conduce_v very_o much_o for_o drain_n water_n out_o of_o every_o place_n or_o cavity_n of_o the_o body_n in_o truth_n it_o be_v manifest_a by_o frequent_a experience_n these_o do_v often_o cure_v a_o anasarca_n before_o any_o other_o remedy_n let_v we_o see_v what_o they_o may_v effect_v for_o the_o empty_n the_o cavity_n of_o the_o abdomen_fw-la as_o to_o this_o it_o first_o appear_v ascite_v what_o profit_n they_o bring_v in_o a_o ascite_v that_o there_o be_v no_o passage_n immediate_o open_a from_o a_o ascitick_a pool_n to_o the_o reins_o although_o contiguous_a but_o that_o whatsoever_o water_n be_v transfer_v from_o hence_o thither_o must_v of_o necessity_n first_o be_v drink_v up_o into_o the_o mass_n of_o blood_n and_o from_o thence_o be_v pour_v out_o of_o its_o bosom_n into_o the_o sink_n of_o urine_n and_o true_o it_o be_v but_o a_o little_a which_o the_o gape_a little_a mouth_n of_o the_o vein_n about_o the_o superficies_n of_o the_o bowel_n can_v receive_v if_o perhaps_o they_o be_v open_a at_o all_o and_o diuretic_n can_v but_o effect_v this_o one_o thing_n that_o by_o pour_v forth_o the_o blood_n and_o force_v its_o serosity_n more_o plentiful_o to_o the_o kidney_n they_o cause_v the_o water_n fluctuate_a in_o the_o belly_n to_o be_v allure_v to_o it_o be_v so_o empty_v in_o the_o mean_a time_n there_o be_v no_o less_o danger_n lest_o diuretic_n be_v unreasonable_o administer_v while_o they_o dissolve_v the_o blood_n too_o much_o they_o constrain_v the_o serum_fw-la to_o depart_v into_o the_o seat_n of_o the_o ascite_v more_o than_o into_o the_o reins_o and_o so_o rather_o augment_v than_o remove_v the_o inundation_n of_o the_o belly_n for_o that_o it_o sometime_o so_o happen_v i_o have_v often_o find_v by_o experience_n wherefore_o when_o diuretic_n be_v prescurbed_a to_o cure_v a_o ascite_v we_o must_v chielfy_a provide_v against_o such_o a_o contrary_a effect_n for_o this_o reason_n indeed_o astringent_n and_o corroborative_n be_v always_o mix_v in_o remedy_n for_o the_o dropsy_n found_v on_o experience_n and_o the_o authority_n and_o practice_n of_o the_o ancient_n not_o that_o such_o as_o be_v common_o say_v do_v confirm_v the_o tone_n of_o the_o liver_n but_o conserve_v the_o temperature_n and_o mixture_n of_o the_o blood_n lest_o it_o be_v whole_o dissolve_v by_o too_o great_a a_o fusion_n wherefore_o in_o a_o ascite_v which_o chief_o or_o in_o part_n happen_v by_o reason_n of_o the_o frame_n of_o the_o bowel_n and_o vessel_n and_o chief_o the_o coat_n glandule_n and_o their_o little_a string_n and_o their_o interspace_n be_v stuff_v by_o a_o serous_a humour_n and_o therefore_o very_o much_o swell_v up_o as_o cathartic_o so_o also_o diuretics_n profit_n and_o be_v frequent_o take_v with_o success_n forasmuch_o as_o by_o the_o use_n of_o these_o the_o mass_n of_o blood_n be_v empty_v the_o serum_fw-la be_v more_o plentiful_o derive_v to_o the_o kidney_n do_v easy_o reveive_v unto_o itself_o those_o water_n every_o where_o stagnate_v about_o their_o little_a mouth_n and_o convey_v it_o towards_o the_o urinary_a sink_n but_o on_o the_o contrary_a in_o a_o mere_a ascite_n where_o the_o heap_n of_o water_n do_v overflow_v the_o cavity_n of_o the_o belly_n the_o texture_n of_o the_o bowel_n be_v free_a from_o the_o serous_a stuff_n diuretic_n be_v give_v in_o vain_a or_o incommodious_o inasmuch_o as_o they_o express_v nothing_o from_o this_o lake_n of_o the_o belly_n and_o most_o frequent_o by_o dissolve_v the_o blood_n more_o impetuous_o drive_v together_o the_o water_n apt_a to_o be_v instill_a there_o not_o all_o diuretic_n of_o every_o kind_n be_v equal_o convenient_a in_o a_o ascite_v administer_v with_o what_o choice_n and_o difference_n they_o ought_v to_o be_v administer_v neither_o ought_v they_o indifferent_o to_o be_v administer_v for_o we_o must_v observe_v the_o affect_a in_o this_o disease_n for_o the_o most_o part_n make_v a_o little_a red_a urine_n and_o as_o it_o be_v lixivial_a which_o true_o be_v a_o indication_n that_o the_o temperature_n of_o he_o blood_n be_v too_o much_o bind_v in_o they_o by_o reason_n of_o the_o fix_a and_o sulphureous_a salt_n exalt_v and_o combine_v together_o and_o therefore_o that_o the_o serum_n be_v not_o due_o separate_v within_o the_o reins_o which_o notwithstanding_o be_v shake_v off_o about_o the_o wind_n of_o the_o obstruct_a bowel_n and_o so_o be_v depisit_v in_o the_o cavity_n of_o the_o belly_n wherefore_o in_o this_o case_n it_o will_v be_v convenient_a to_o drink_v only_o those_o thing_n to_o excite_v urine_n which_o so_o restore_v and_o amend_v the_o constitution_n of_o the_o blood_n that_o the_o enormity_n of_o the_o fix_a salt_n and_o sulphur_n be_v take_v away_o the_o serous_a part_n may_v be_v separate_v within_o the_o reins_o and_o more_o plentiful_o discharge_v for_o which_o purpose_n not_o acid_a or_o lixivial_a thing_n but_o those_o endow_v with_o a_o volatile_a salt_n be_v appoint_v for_o i_o have_v often_o observe_v in_o patient_n of_o that_o kind_n when_o the_o spirit_n of_o salt_n and_o other_o acid_a drop_n of_o mineral_n and_o when_o the_o dissolution_n and_o deliquium_n of_o salt_n of_o tartar_n broom_n and_o other_o thing_n have_v do_v more_o hurt_n than_o good_a that_o the_o juice_n of_o plantain_n brooklime_n and_o other_o herb_n abound_v with_o a_o volatile_a salt_n have_v much_o help_v as_o also_o the_o expression_n of_o millepedes_n for_o the_o same_o reason_n salt_n of_o nitre_n thorough_o purify_v or_o crystal_a mineral_n do_v often_o profit_n form_n of_o medicine_n more_o accommodate_v for_o this_o use_n be_v extant_a in_o our_o former_a treatise_n where_o viz._n example_n of_o diuretic_n be_v describe_v in_o which_o both_o volatile_a and_o nitrous_a salt_n be_v the_o basis_n moreover_o hither_o aught_o to_o be_v refer_v the_o notable_a experiment_n by_o which_o joannes_n anglus_fw-la affirm_v himself_o often_o to_o have_v cure_v the_o ascite_n from_o a_o hot_a cause_n remedy_n john_n english_a his_o empyrical_a remedy_n which_o medicine_n also_o that_o expert_a physician_n dr._n theodore_n mayern_n be_v wont_a to_o magnify_v and_o prescribe_v in_o the_o like_a case_n take_v of_o the_o juice_n of_o plantain_n and_o liverwort_n and_o fill_v a_o earthen_a pot_n to_o the_o top_n which_o be_v stop_v close_o put_v in_o a_o hot_a oven_n after_o the_o bread_n be_v draw_v and_o make_v a_o little_a fire_n on_o the_o side_n of_o the_o pot_n to_o continue_v the_o heat_n of_o the_o oven_n after_o it_o be_v so_o boil_a strain_n it_o and_o be_v sweeten_v with_o sugar_n drink_v of_o it_o morning_n and_o evening_n and_o it_o cure_v in_o imitation_n of_o this_o i_o have_v often_o with_o success_n prescribe_v as_o follow_v take_v of_o green_a plantane-leaves_a four_o handful_n liverwort_n brooklime_n of_o each_o two_o handful_n bruise_v they_o together_o and_o pour_v upon_o they_o half_a a_o pound_n of_o small_a compound_n radish-water_n or_o other_o appropriate_a aagistral_a express_v it_o strong_o the_o dose_n three_o ounce_n three_o time_n in_o a_o day_n although_o diaphoretick_n be_v most_o efficacious_a in_o a_o anasarca_fw-la ascite_v how_o beneficial_a diaphoretick_n be_v in_o a_o ascite_v yet_o in_o a_o ascite_v they_o be_v rare_o or_o not_o at_o all_o use_v for_o be_v unreasonable_o offer_v they_o impress_v ofttimes_o great_a hurt_n on_o the_o patient_n without_o any_o avail_n forasmuch_o indeed_o as_o by_o heat_n the_o blood_n they_o cause_v the_o fluctuate_a water_n to_o grow_v hot_a and_o as_o it_o be_v to_o boil_v in_o the_o hollowness_n of_o the_o belly_n so_o that_o the_o spirit_n and_o humour_n be_v disturb_v by_o vapour_n raise_v from_o thence_o and_o so_o a_o disorder_n of_o all_o the_o function_n follow_v and_o the_o very_a bowel_n be_v as_o it_o be_v boil_a be_v much_o prejucice_v moreover_o from_o sweat_v unadvised_o institute_v the_o blood_n be_v force_v into_o a_o fusion_n and_o precipitation_n of_o the_o serum_n throw_v it_o off_o the_o more_o into_o the_o nest_n of_o the_o ascite_v wherefore_o when_o some_o prescribe_v fomentation_n and_o liniment_n adn_o bathe_v to_o be_v apply_v to_o the_o swell_a paunch_n of_o the_o belly_n for_o the_o most_o part_n it_o turn_v to_o the_o worse_a in_o such_o patient_n for_o beside_o a_o little_a fever_n a_o vertigoe_n faint_v of_o the_o spirit_n and_o other_o ill_a symptom_n of_o the_o brain_n and_o heart_n be_v most_o
of_o such_o kind_n of_o particle_n which_o be_v mild_a and_o thin_a may_v be_v tame_v by_o the_o blood_n and_o assimilate_v without_o any_o effervescence_n or_o heat_n wherefore_o ass_n milk_n also_o sometime_o cow_n or_o goat_n milk_n also_o water-gruel_n cream_n of_o barley_n ptisan_n almond-milks_a and_o other_o simple_a nourishment_n will_v better_o agree_v and_o nourish_v more_o than_o flesh_n egg_n and_o gelly-broath_n strong_a ale_n wine_n or_o any_o other_o kind_n of_o rich_a fare_n second_o away_o 2._o that_o the_o acidity_n of_o the_o blood_n and_o other_o humour_n be_v take_v away_o that_o the_o blood_n retain_v its_o own_o temperament_n be_v not_o easy_o dissolve_v into_o serosity_n injurious_a to_o the_o lung_n it_o behoove_v that_o as_o well_o the_o acidity_n of_o itself_o as_o of_o other_o humour_n mix_v therewith_o and_o chief_o the_o nervous_a and_o limpid_a one_o be_v destroy_v which_o intention_n medicine_n prepare_v with_o brimstone_n will_v best_o accomplish_v which_o for_o that_o cause_n in_o this_o case_n provide_v a_o hectic_a fever_n be_v not_o present_a may_v be_v more_o frequent_o and_o in_o abundance_n take_v wherefore_o the_o tincture_n the_o balsam_n the_o syrup_n the_o flower_n and_o milk_n of_o sulphur_n in_o somewhat_o a_o large_a dose_n may_v be_v exhibit_v twice_o or_o thrice_o a_o day_n for_o the_o same_o reason_n traumatic_a or_o vulnerary_a decoction_n also_o decoction_n of_o the_o pectoral_a herb_n common_o so_o call_v also_o of_o the_o wood_n be_v to_o be_v take_v instead_o of_o ordinary_a drink_n moreover_o the_o powder_n of_o crab_n eye_n hoglouse_n and_o other_o thing_n endue_v with_o a_o alcali_n or_o volatile_a salt_n be_v often_o administer_v with_o great_a success_n lung_n 3._o that_o the_o excrement_n of_o the_o blood_n be_v draw_v off_o from_o the_o lung_n the_o three_o intention_n of_o heal_v respect_v the_o first_o indication_n viz._n that_o the_o superfluous_a dregs_o of_o the_o deprave_a blood_n if_o they_o shall_v be_v very_o much_o predominant_a be_v command_v out_o from_o the_o lung_n may_v be_v discharge_v by_o other_o emunctory_n suggest_v very_o many_o way_n to_o be_v use_v for_o their_o dispatch_n for_o beside_o phlebotomy_n diuresie_n and_o sometime_o a_o gentle_a purgation_n which_o take_v place_n in_o all_o cough_n yea_o in_o the_o begin_n of_o a_o consumptive_a cough_n or_o phthisis_fw-la hither_o also_o ought_v to_o be_v refer_v bath_n take_v in_o a_o more_o warm_a air_n whereby_o they_o may_v more_o free_o transpire_v also_o friction_n of_o the_o extreme_a part_n dropace_n issue_n blistering_n or_o depilatory_n errhine_n gargles_n and_o other_o private_a or_o public_a sluice_n either_o of_o humour_n or_o vapour_n the_o second_o indication_n in_o the_o begin_n of_o a_o phthisis_fw-la viz._n that_o the_o consumptive_a matter_n lay_v aside_o within_o the_o lung_n may_v be_v easy_o and_o daily_o evacuate_v medicine_n second_o indication_n require_v expectorate_n medicine_n be_v perform_v by_o expectorate_n medicine_n these_o be_v say_v to_o operate_v after_o a_o twofold_a matter_n according_a to_o which_o their_o virtue_n be_v convey_v two_o way_n to_o the_o lung_n for_o of_o those_o be_v take_v by_o the_o mouth_n some_o immediate_o dismiss_v their_o active_a particle_n into_o the_o trachea_n which_o partly_o by_o make_v the_o way_n slippery_a and_o loosen_v the_o matter_n impact_v and_o partly_o by_o provoke_v the_o excretory_n fibres_fw-fr into_o convulsion_n do_v procure_v expectoration_n in_o which_o number_n be_v chief_o account_v linctus_n and_o fumigation_n the_o expectorate_n remedy_n of_o another_o kind_n which_o deserve_o be_v account_v more_o available_a do_v exercise_v their_o energy_n by_o the_o passage_n of_o the_o blood_n for_o whereas_o they_o consist_v of_o such_o kind_n of_o particle_n which_o can_v be_v digest_v and_o assimilate_v by_o the_o mass_n of_o blood_n be_v spread_v through_o the_o blood_n because_o they_o can_v be_v mix_v with_o it_o they_o be_v present_o again_o exterminate_v and_o so_o penetrate_v from_o the_o pneumonic_a artery_n into_o the_o tracheal_n passage_n where_o light_v on_o the_o matter_n they_o divide_v and_o attenuate_v and_o so_o disturb_v it_o that_o the_o little_a fibre_n be_v irritate_v from_o thence_o and_o successive_o contract_v while_o they_o cough_v the_o content_n of_o the_o trachea_n and_o of_o its_o little_a bladder_n be_v eject_v upward_o into_o the_o mouth_n medicine_n proper_a for_o this_o use_n beside_o sulphur_n and_o the_o preparation_n of_o it_o be_v artificial_a balsam_n distil_v with_o oil_n of_o turpentine_n tincture_n and_o syrup_n of_o gum_n ammoniac_a galbanum_fw-la asa_n foetida_fw-la garlick_n leek_n and_o such_o like_o yield_v a_o strong_a scent_n from_o which_o also_o lohoch_n and_o eclegma_n be_v prepare_v and_o these_o work_n both_o way_n partly_o by_o drip_v into_o the_o trachea_n and_o partly_o by_o enter_v the_o lung_n by_o the_o circulation_n of_o the_o blood_n and_o assault_v the_o morbific_a matter_n both_o before_o and_o behind_o and_o so_o exclude_v it_o with_o the_o great_a force_n 3._o what_o belong_v to_o the_o three_o indication_n viz._n that_o the_o frame_n of_o the_o lung_n be_v hurt_v or_o their_o constitution_n vitiate_v may_v be_v either_o restore_v or_o amend_v vulneraries_n three_o indication_n be_v perform_v by_o balsamick_n and_o vulneraries_n such_o thing_n be_v of_o use_n as_o resist_a putrefaction_n do_v cleanse_v heal_v dry_a and_o strengthen_v to_o which_o intent_n also_o remedy_n prepare_v of_o sulphur_n balsamics_n and_o vulneraries_n do_v agree_v hence_o some_o empiric_n do_v not_o only_o successful_o prescribe_v the_o smoke_n of_o sulphur_n vivum_fw-la but_o also_o of_o auripigmentum_n to_o be_v suck_v through_o a_o pipe_n or_o funnel_n into_o the_o lung_n moreover_o it_o be_v for_o this_o reason_n that_o change_n of_o air_n and_o soil_n viz._n from_o city_n to_o the_o country_n or_o sulphureous_a air_n or_o the_o passage_n from_o one_o region_n into_o another_o that_o be_v hot_a be_v of_o such_o a_o signal_n advantage_n hitherto_o of_o the_o method_n of_o healing_n which_o seem_v to_o be_v of_o use_n against_o the_o more_o painful_a cough_n or_o phthisis_fw-la beginning_n now_o it_o remain_v according_a to_o all_o those_o curatory_n indication_n to_o subjoin_v certain_a select_a form_n of_o medicine_n which_o also_o according_a to_o the_o way_n of_o heal_v describe_v above_o in_o a_o slight_a cough_n which_o be_v short_a of_o a_o phthisis_fw-la consumption_n form_n of_o remedy_n for_o a_o consumption_n we_o shall_v distinguish_v into_o certain_a rank_n viz._n which_o be_v mixture_n linctus_n lohoch_n tincture_n balsam_n troche_n lozenge_n powder_n pill_n decoction_n and_o distil_a water_n we_o shall_v set_v down_o some_o example_n of_o each_o of_o these_o whereto_o also_o may_v be_v refer_v some_o of_o the_o form_n of_o medicine_n before_o describe_v for_o a_o beginning_n cough_n and_o not_o as_o yet_o consumptive_a 1._o magisterial_a medicine_n and_o syrup_n take_v of_o our_o syrup_n of_o sulphur_n three_o ounce_n mixture_n mixture_n water_n of_o earthworm_n a_o ounce_n tincture_n of_o saffron_n two_o dram_n mingle_v they_o take_v one_o spoonful_n at_o night_n and_o first_o in_o the_o morning_n take_v of_o syrup_n of_o the_o juice_n of_o ground-ivy_n three_o ounce_n snail-water_n a_o ounce_n flour_v of_o brimstone_n a_o dram_n mix_v they_o by_o shake_v the_o do_v one_o spoonful_n at_o night_n and_o morning_n take_v of_o tincture_n of_o sulphur_n two_o dram_n laudanum_n tartarizate_v a_o dram_n syrup_n of_o the_o juice_n of_o ground-ivy_n two_o ounce_n cinamon-water_n two_o dram_n the_o dose_n one_o spoonful_n at_o bedtime_n and_o if_o sleep_v be_v want_v towards_o morning_n syrupus_fw-la diasulphuris_n take_v of_o sulphur_n prepare_v after_o our_o manner_n half_a a_o ounce_n syrup_n syrup_n best_a canary_n wine_n two_o pint_n let_v they_o be_v digest_v 28_o hour_n in_o a_o water_n or_o sand_n bath_n which_o be_v do_v take_v of_o the_o fine_a sugar_n two_o pound_n dissolve_v in_o elder-flower-water_n and_o boil_v to_o a_o height_n to_o make_v tablet_n afterward_o pour_v to_o it_o by_o little_a and_o little_a wine_n colour_v with_o sulphur_n and_o warm_a let_v it_o boil_v a_o little_a on_o the_o fire_n strain_v it_o through_o woollen_a you_o will_v have_v a_o most_o delicate_a syrup_n of_o a_o gold_n colour_n and_o for_o cough_n and_o other_o distemper_n of_o the_o lung_n where_o a_o hectic_a fever_n and_o heat_n of_o the_o praecordium_n be_v absent_a most_o profitable_a the_o do_v a_o spoonful_n morning_n and_o evening_n by_o itself_o or_o with_o other_o pectoral_o syrup_n of_o garlic_n take_v ten_o or_o twelve_o clove_n of_o garlic_n strip_v from_o the_o little_a skin_n and_o cut_v into_o slice_n aniseed_n bruise_v half_o a_o ounce_n elicampane_z slice_v three_o dram_n liquorish_a two_o dram_n let_v they_o digest_v for_o two_o or_o three_o day_n in_o a_o pint_n and_o half_a of_o spirit_n of_o wine_n close_a and_o
in_o the_o underlie_a water_n they_o sometime_o imbibe_n they_o be_v turn_v into_o vapour_n and_o so_o dispatch_v they_o to_o the_o blood_n or_o continual_o exhale_v they_o with_o air_n come_v out_o at_o the_o mouth_n that_o a_o effect_n of_o this_o sort_n may_v more_o easy_o happen_v to_o cure_v this_o disease_n medicinal_a aid_n be_v take_v for_o that_o intention_n therefore_o the_o passage_n of_o blood_n air_n and_o humour_n ought_v to_o be_v empty_v as_o much_o as_o may_v be_v and_o to_o be_v keep_v so_o empty_a for_o this_o purpose_n purge_n diuretic_n and_o more_o mild_a diaphoretick_n be_v methodical_o and_o alternate_o exhibit_v also_o remedy_n for_o the_o breast_n and_o expectorate_n challenge_v here_o their_o place_n let_v the_o diet_n be_v slender_a and_o warm_a and_o a_o government_n appoint_v as_o to_o all_o other_o thing_n of_o that_o nature_n that_o the_o blood_n may_v be_v make_v to_o exhale_v the_o more_o and_o all_o the_o superfluous_a humour_n to_o evaporate_v i_o think_v good_a to_o annex_v some_o form_n of_o medicine_n accommodate_v to_o these_o use_n take_v of_o chervil-root_n knee-holme_a polypodie_fw-mi of_o the_o oak_n of_o each_o a_o ounce_n agrimony_n hydromel_n a_o purge_v hydromel_n white_a maidenhair_n oak_n of_o jerusalem_n ground_n ivy_n of_o each_o one_o handful_n carthamus-seed_n one_o ounce_n florence_n orris_n half_a a_o ounce_n seed_n of_o danewort_n 5_o dram_n calamus_fw-la aromaticus_fw-la half_a a_o ounce_n boil_v they_o in_o four_o pound_n of_o spring-water_n to_o the_o consumption_n of_o a_o three_o part_n add_v to_o it_o be_v strain_v senna_n one_o ounce_n and_o a_o half_a agaric_a tow_n dram_n mechoacan_a and_o turbith_n of_o each_o half_n a_o ounce_n yellow_a sanders_n a_o dram_n and_o a_o half_a galangal_n the_o less_o one_o dram_n boil_v they_o two_o hour_n gentle_o and_o close_o cover_v afterward_o strain_v it_o and_o add_v of_o honey_n two_o ounce_n clarify_v it_o with_o the_o white_a of_o a_o egg_n make_v a_o purge_a hydromel_n the_o do_v be_v from_o six_o ounce_n to_o eight_o in_o the_o morning_n twice_o or_o thrice_o in_o a_o week_n or_o take_v mercurius_n dulcis_fw-la one_o scruple_n resine_n of_o jallap_v half_a a_o scruple_n balsam_n of_o peruwhat_o suffice_v to_o make_v four_o pill_n to_o be_v take_v in_o the_o morning_n and_o to_o be_v repeat_v within_o five_o or_o six_o day_n take_v tincture_n of_o sulphur_n three_o dram_n take_v from_o seven_o drop_n to_o ten_o tincture_n tincture_n at_o night_n and_o in_o the_o morning_n in_o a_o spoonful_n of_o the_o follow_a mixture_n drink_v after_o it_o three_o spoonful_n take_v of_o the_o water_n of_o snail_n earth_n worm_n and_o compound_v rhadish_a water_n julep_n julep_n of_o each_o four_o ounce_n water_n of_o elderberry_n ferment_v one_o pound_n syrup_n of_o juice_n of_o ground-ivy_n two_o ounce_n mix_v they_o for_o a_o julep_n or_o take_v of_o tincture_n of_o ammoniacum_n or_o galbanum_fw-la take_v twenty_o drop_n evening_n and_o morning_n in_o the_o same_o mixture_n or_o take_v of_o hoglouse_n prepare_v two_o dram_n flower_n of_o sulphur_n two_o scruple_n pill_n pill_n flower_n of_o benzoin_n one_o scruple_n powder_n of_o wild_a carrot_n and_o burdock-seed_n of_o each_o half_n a_o dram_n turpentine_n of_o venice_n enough_o to_o make_v a_o mass_n make_v small_a pill_n take_v four_o evening_n and_o morning_n drink_v after_o they_o a_o small_a draught_n of_o the_o julep_n at_o nine_o a_o clock_n in_o the_o morning_n and_o five_o in_o the_o afternoon_n limewater_n a_o limewater_n let_v he_o take_v four_z once_z of_o the_o compound_v limewater_n by_o itself_o or_o with_o any_o other_o proper_a remedy_n for_o ordinary_a drink_n take_v the_o follow_a bochete_n take_v sarsaperilla_n six_o ounce_n china_n two_o ounce_n white_a and_o yellow_a sander_n bochet_n a_o bochet_n of_o each_o six_o dram_n shave_n of_o ivory_n and_o hartshorn_n of_o each_o three_o dram_n calamus_fw-la aromaticus_fw-la half_a a_o ounce_n raisin_n half_a a_o pound_n liquorish_a three_o dram_n boil_v and_o infuse_v they_o in_o twelve_o pound_n of_o spring-water_n to_o six_o pound_n strain_v it_o former_o about_o twenty_o five_o year_n since_o when_o i_o reside_v at_o oxford_n patient_n a_o history_n of_o a_o patient_n i_o be_v send_v for_o to_o a_o young_a scholar_n who_o suffer_v for_o three_o week_n space_n under_o a_o pain_n of_o the_o thorax_n and_o a_o most_o grievous_a dyspnoea_fw-la constant_o trouble_v he_o in_o the_o evening_n moreover_o from_o a_o more_o quick_a motion_n of_o body_n or_o go_v more_o hasty_o than_o usual_o up_o any_o steep_a place_n he_o labour_v extreme_o he_o can_v not_o lie_v down_o long_o on_o either_o side_n but_o be_v necessitate_v to_o lie_v in_o his_o bed_n supone_v and_o his_o head_n erect_v if_o perhaps_o he_o attempt_v to_o lie_v on_o either_o side_n immediate_o pain_n follow_v that_o position_n of_o body_n and_o if_o perhaps_o he_o roll_v himself_o from_o one_o side_n to_o another_o the_o pain_n be_v also_o present_o translate_v he_o feel_v as_o it_o be_v water_n to_o wave_v from_o place_n to_o place_n hence_o i_o have_v a_o just_a suspicion_n of_o a_o dropsy_n of_o the_o breast_n whereof_o that_o i_o may_v be_v more_o assure_v i_o order_v that_o lie_v upon_o his_o back_n on_o his_o bed_n he_o will_v suffer_v his_o head_n to_o bend_v backward_o from_o the_o bedside_n to_o the_o floor_n immediate_o he_o have_v a_o plain_a perception_n of_o water_n run_v towards_o the_o clavicle_n together_o with_o a_o change_n of_o the_o pain_n thither_o moreover_o if_o at_o any_o time_n he_o grow_v more_o hot_a than_o usual_a from_o motion_n or_o in_o his_o bed_n or_o by_o the_o fire_n he_o present_o feel_v sensible_o in_o his_o breast_n as_o it_o be_v water_n boil_v over_o the_o fire_n and_o also_o complain_v of_o a_o vertigo_n and_o a_o small_a decay_n of_o spirit_n wherefore_o when_o we_o may_v lawful_o collect_v out_o of_o these_o thing_n right_o consider_v that_o he_o be_v affect_v with_o a_o dropsy_n of_o the_o breast_n i_o prescribe_v the_o follow_a method_n and_o medicine_n with_o success_n take_v of_o mercurius_n dulcis_fw-la fifteen_o grain_n he_o the_o cure_n of_o he_o resine_n of_o jallap_v half_a a_o scruple_n syrup_n of_o rose_n solutive_a what_o suffice_v make_v three_o pill_n he_o take_v they_o early_o in_o the_o morning_n and_o have_v twelve_o stool_n with_o great_a ease_n afterward_o on_o the_o three_o day_n by_o the_o same_o medicine_n he_o have_v but_o four_o but_o with_o great_a benefit_n he_o take_v afterward_o for_o many_o day_n six_o ounce_n of_o the_o pectoral_a and_o diuretic_n apozem_v twice_o in_o a_o day_n and_o last_o repeat_v the_o purge_n he_o perfect_o recover_v sect_n ii_o of_o splanchnick_a remedy_n or_o those_o which_o respect_v the_o bowel_n of_o the_o low_a belly_n chap._n i._o of_o the_o jaundice_n and_o the_o remedy_n thereof_o and_o the_o manner_n and_o reason_n of_o their_o operation_n hitherto_o we_o have_v large_o enough_o unfold_v the_o pathologie_n and_o curatory_n method_n of_o the_o thorax_n now_o it_o follow_v next_o to_o finish_v our_o task_n in_o like_a manner_n about_o the_o low_a belly_n but_o we_o have_v in_o our_o former_a tract_n for_o the_o most_o part_n describe_v already_o the_o medicine_n belong_v to_o this_o region_n and_o the_o manner_n and_o reason_n of_o their_o work_n together_o with_o the_o anatomy_n of_o the_o stomach_n and_o intestine_n we_o have_v treat_v of_o remedy_n stomachical_a dysenterical_a and_o other_o belong_v to_o the_o intestine_n as_o also_o diuretic_n together_o with_o the_o reason_n of_o they_o moreover_o we_o have_v sussicent_o elsewhere_o handle_v the_o aetioligie_n of_o hypochondriack_n and_o hysterical_a remedy_n what_o therefore_o remain_v of_o hepatical_a distemper_n as_o well_o proper_a as_o of_o those_o vulgar_o ascribe_v thereunto_o and_o of_o their_o remedy_n we_o will_v discourse_v in_o this_o section_n notwithstanding_o in_o each_o of_o these_o we_o will_v bestow_v more_o labour_n about_o the_o curatory_n than_o pathological_a part_n the_o chief_a disease_n by_o which_o the_o liver_n and_o the_o appendix_n thereof_o liver_n disease_n of_o the_o liver_n be_v wont_a to_o be_v encumber_v be_v the_o jaundice_n and_o a_o tumour_n and_o under_o this_o latter_a many_o other_o affect_v viz._n obstruction_n inflammation_n induration_n and_o schirrus_n be_v number_v to_o all_o which_o be_v vulgar_o appoint_v remedy_n common_o call_v hepaticks_n and_o which_o make_v up_o a_o great_a part_n of_o the_o dispensatory_a the_o jaundice_n be_v either_o a_o disease_n by_o itself_o primary_o begin_v which_o be_v here_o proper_o treat_v of_o or_o it_o be_v a_o effect_n or_o product_v of_o another_o disease_n as_o when_o it_o arise_v upon_o a_o intermit_a fever_n which_o oftentimes_o it_o put_v a_o end_n to_o of_o which_o also_o we_o will_v present_o treat_v by_o the_o by_o a_o icterical_a distemper_n
administer_v both_o a_o dropace_n and_o vesicatory_a also_o by_o apply_v still_o the_o same_o plaster_n the_o scarf-skin_n be_v blister_a and_o take_v off_o and_o the_o place_n be_v red_a and_o ulcerate_v and_o only_o wipe_v it_o once_o or_o twice_o in_o a_o day_n and_o put_v it_o on_o again_o they_o cause_v the_o little_a ulcer_n raise_v by_o the_o vesicatory_a to_o flow_v at_o pleasure_n yea_o sometime_o above_o a_o month_n and_o to_o throw_v off_o a_o plentiful_a ichor_n other_o enclose_v cantharides_n bruise_v and_o sprinkle_v with_o vinegar_n in_o silk_n and_o apply_v to_o the_o place_n some_o empiric_n use_v in_o the_o room_n of_o cantharides_n a_o mass_n of_o the_o leaf_n of_o crowfoot_n or_o flamula_fw-la jovis_n bruise_v on_o the_o place_n by_o which_o the_o scarf-skin_n be_v blister_v or_o rather_o eat_v the_o skin_n itself_o as_o if_o touch_v with_o a_o actual_a fire_n be_v much_o inflame_v and_o deep_o ulcerate_v whence_o not_o only_o a_o profusion_n of_o ichor_n but_o a_o inflammation_n of_o the_o whole_a member_n and_o a_o feverish_a disposition_n sometime_o follow_v wherefore_o these_o thing_n be_v not_o to_o be_v use_v rash_o 2._o operate_v 2._o how_o they_o operate_v if_o it_o be_v inquire_v of_o the_o manner_n and_o reason_n how_o these_o and_o other_o vesicatories_n operate_v in_o the_o first_o place_n we_o ought_v to_o show_v by_o what_o manner_n actual_a fire_n and_o thing_n endue_v with_o particle_n proceed_v from_o fire_n do_v raise_v a_o blister_n then_o by_o a_o easy_a analogy_n the_o force_n and_o manner_n of_o work_v of_o those_o sort_n of_o remedy_n will_v be_v know_v which_o be_v report_v to_o be_v endow_v with_o a_o potential_a fire_n wherefore_o we_o observe_v of_o the_o former_a that_o the_o fiery_a particle_n not_o be_v too_o vehement_o apply_v penetrate_v the_o scarf-skin_n without_o dissolution_n of_o unity_n enter_v under_o the_o skin_n itself_o fire_n show_v by_o the_o example_n of_o fire_n where_o the_o extremity_n of_o the_o vessel_n bring_v blood_n of_o the_o nerve_n and_o of_o the_o nervons_fw-fr fibres_fw-fr be_v terminate_v and_o there_o do_v various_o twist_v together_o these_o alter_v they_o from_o their_o position_n and_o pervert_v the_o structure_n of_o the_o whole_a texture_n of_o the_o skin_n insomuch_o that_o from_o all_o the_o vessel_n be_v make_v angry_a in_o a_o high_a degree_n the_o watery_a humour_n be_v imbue_v with_o igneous_a particle_n and_o therefore_o reject_v as_o well_o by_o the_o blood_n as_o by_o the_o nervous_a juice_n be_v spew_v out_o in_o great_a abundance_n this_o lympha_fw-la because_o it_o can_v pass_v through_o the_o scarf-skin_n separate_v it_o from_o the_o skin_n and_o raise_v it_o into_o a_o bladdery_a bulk_n from_o which_o at_o length_n be_v break_v of_o its_o own_o accord_n or_o occasional_o it_o flow_v out_o moreover_o as_o long_o as_o the_o igneous_a particle_n adhere_v to_o the_o skin_n and_o the_o mouth_n of_o the_o vessel_n be_v cover_v with_o a_o eschar_n be_v not_o close_v up_o these_o be_v continual_o twitch_v by_o they_o do_v continue_v to_o spew_v out_o the_o ichor_n this_o kind_n of_o ichorous_a flux_n will_v the_o soon_o cease_v if_o immediate_o upon_o the_o hurt_n inflict_v the_o fiery_a particle_n be_v draw_v out_o by_o the_o application_n of_o some_o proper_a antipyretick_n as_o fire_n itself_o nitre_n soap_n onion_n and_o the_o like_a moreover_o it_o run_v the_o long_o if_o omit_v a_o antipyretick_n medicine_n hinder_v the_o generation_n of_o a_o cicatrice_n or_o of_o the_o outer-skin_n and_o unlock_v the_o mouth_n of_o the_o vessel_n be_v wear_v upon_o the_o place_n affect_v by_o these_o it_o be_v easy_a to_o understand_v by_o what_o manner_n vesicatory_n perform_v their_o operation_n water_n how_o cantharides_n excite_v blister_n and_o draw_v forth_o water_n viz._n cantharides_n as_o likewise_o any_o other_o of_o the_o same_o virtue_n be_v outward_o apply_v and_o be_v heat_v by_o effluvia_n of_o the_o part_n subject_v and_o so_o be_v provoke_v to_o exert_v their_o power_n do_v plentiful_o dispatch_v sharp_a and_o as_o it_o be_v fiery_a particle_n from_o themselves_o which_o penetrate_v the_o scarf-skin_n without_o any_o tear_v it_o they_o be_v dash_v against_o the_o cutis_fw-la or_o other_o skin_n where_o first_o they_o act_n upon_o the_o spirit_n and_o then_o by_o the_o affect_v these_o upon_o the_o humour_n and_o solid_a part_n they_o very_o much_o provoke_v the_o spirit_n and_o drive_v they_o into_o painful_a convulsion_n of_o the_o fibre_n dissolve_v the_o humour_n and_o constrain_v they_o to_o separate_v into_o part_n so_o that_o the_o watery_a part_n be_v very_o much_o embue_v with_o those_o sharp_a and_o as_o it_o be_v venomous_a particle_n be_v reject_v every_o where_n by_o the_o other_o juice_n and_o when_o in_o the_o mean_a time_n the_o end_n of_o the_o vessel_n and_o fibre_n be_v either_o eat_v by_o the_o burn_a or_o open_v by_o twitch_a and_o as_o it_o be_v drain_v that_o ichor_n convey_v the_o hurtful_a particle_n be_v plentiful_o spew_v out_o of_o their_o little_a mouth_n which_o then_o separated_n the_o impervious_a cuticula_fw-la or_o the_o scarf-skin_n from_o the_o other_o skin_n or_o cutis_fw-la be_v self_n and_o raise_v it_o into_o a_o little_a bladder_n and_o after_o this_o be_v beoken_v and_o take_v away_o it_o be_v for_o some_o time_n pour_v out_o by_o the_o ulcerate_v shin_n as_o we_o show_v it_o to_o come_v to_o pass_v by_o reason_n of_o the_o particle_n of_o fire_n but_o this_o be_v not_o only_o do_v because_o the_o serous_a juice_n imbibe_v the_o sharp_a part_n of_o the_o medicine_n and_o convey_v they_o out_o do_v not_o always_o bear_v they_o all_o back_o the_o same_o way_n by_o which_o they_o enter_v but_o sometime_o this_o be_v endue_v with_o these_o sting_n regurgitate_v into_o the_o mass_n of_o bloodl_n and_o afterward_o be_v circulate_v with_o it_o and_o eject_v with_o its_o infestous_a burden_n through_o other_o emunctory_n dysurie_n why_o they_o bring_v a_o fervent_a dysurie_n offend_v some_o weak_a or_o tender_a channel_n in_o its_o passage_n or_o go_v forth_o from_o whence_o very_o many_o contract_n a_o strangury_n from_o great_a or_o many_o vesicatories_n by_o reason_n of_o the_o urinary_a passage_n be_v affect_v for_o that_o cause_n with_o acrimony_n or_o erosion_n which_o in_o some_o become_v most_o sharp_a and_o intolerable_a also_o that_o application_n sometime_o bring_v bloody_a urine_n to_o other_o afflict_v with_o the_o stone_n hence_o a_o suspicion_n also_o arise_v that_o those_o who_o have_v tender_a lung_n or_o who_o be_v subject_a to_o a_o consumption_n be_v much_o endager_v by_o this_o medicine_n outward_o apply_v which_o notwithstanding_o i_o have_v not_o know_v happen_v to_o any_o but_o can_v reather_n attest_v by_o frequent_a experience_n on_o the_o other_o side_n that_o it_o redound_v to_o advantage_n rather_o than_o hurt_v for_o the_o more_o sharp_a particle_n of_o cantharides_n if_o they_o be_v long_o apply_v be_v sometime_o imbibe_v more_o plentiful_o by_o the_o blood_n infect_v its_o whole_a serum_n which_o juice_n so_o sharpen_v as_o long_o as_o it_o be_v confound_v with_o the_o balsamic_a blood_n hurt_v no_o part_n but_o be_v separate_v from_o it_o by_o the_o kidney_n it_o sometime_o bring_v hurt_v to_o they_o and_o frequent_o not_o only_a twitch_n the_o neck_n of_o the_o bladder_n by_o its_o acrimony_n but_o sometime_o corrode_a it_o cause_n filth_n and_o little_a skin_n nay_o and_o blood_n to_o come_v away_o but_o in_o the_o mass_n of_o blood_n the_o same_o more_o sharp_a saline-volatile_a particle_n do_v often_o most_o notable_o help_v inasmuch_o as_o they_o destroy_v the_o fix_a or_o acid_a salt_n in_o it_o and_o unlock_v the_o consistence_n of_o the_o blood_n too_o much_o bind_v up_o and_o so_o do_v cause_n the_o serous_a and_o other_o morbific_a recrement_n before_o wrap_v up_o with_o it_o to_o be_v separate_v from_o it_o and_o to_o be_v more_o easy_o dispatch_v by_o urine_n and_o sweat_n urine_n vesicatories_n move_v sweat_n and_o urine_n hence_o vesicatory_n be_v apply_v long_o in_o fever_n do_v call_v forth_o plentiful_a urine_n and_o a_o more_o easy_a sweat_n also_o they_o open_v the_o obstruct_a way_n and_o move_v together_o the_o portion_n of_o blood_n or_o serum_n stagnate_v or_o be_v extravasated_a in_o any_o place_n and_o restore_v they_o to_o their_o circulation_n wherefore_o they_o be_v not_o use_v only_o to_o help_v in_o serous_a malady_n but_o also_o in_o those_o of_o the_o blood_n yea_o in_o a_o pleurisy_n peripneumonia_n and_o in_o any_o other_o fever_n have_v hitherto_o show_v after_o what_o manner_n vesicatory_n operate_v first_o on_o the_o spirit_n and_o then_o on_o the_o humour_n and_o solid_a part_n it_o be_v now_o our_o business_n in_o the_o next_o place_n to_o show_v both_o the_o good_a and_o evil_a effectg_n of_o they_o as_o also_o the_o manner_n of_o
this_o excrescency_n be_v easy_o enough_o cure_v by_o sprinkle_v thereon_o escharotick_a powder_n of_o burn_a alum_n colcothar_n or_o mercury_n precipitate_v for_o remedy_n of_o this_o kind_n do_v eat_v away_o the_o flesh_n so_o luxuriate_v by_o their_o acrimony_n as_o well_o as_o stiptickness_n repel_v the_o nutritious_a humour_n deliver_v the_o reason_n thereof_o deliver_v and_o lock_v up_o the_o mouth_n of_o the_o vessel_n as_o often_o as_o that_o superfluous_a flesh_n increase_v about_o the_o side_n of_o the_o issue_n it_o be_v a_o sign_n that_o the_o nutritious_a humour_n flow_v thither_o more_o plentiful_o than_o the_o excrementitious_a and_o for_o that_o cause_n in_o patient_n so_o affect_v that_o vent_n prove_v not_o always_o so_o benign_a wherefore_o under_o pretext_n of_o this_o reason_n many_o be_v averse_a to_o that_o remedy_n though_o sure_o it_o be_v harmless_a to_o most_o although_o not_o alike_o useful_a and_o advantageous_a to_o all_o we_o have_v before_o consider_v the_o chief_a disadvantage_n thereof_o as_o likewise_o the_o scandal_n object_v thereunto_o yet_o there_o remain_v another_o thing_n according_a to_o the_o opinion_n or_o rather_o error_n of_o the_o vulgar_a a_o notable_a objection_n against_o issue_n which_o we_o will_v here_o discuss_v for_o a_o conclusion_n with_o many_o in_o england_n a_o contumacious_a opinion_n be_v grow_v up_o i_o know_v not_o whether_o it_o be_v so_o in_o other_o country_n that_o one_o or_o more_o fontinell_n dispose_n to_o barrenness_n barrenness_n the_o common_a error_n be_v that_o issue_n dispose_v to_o barrenness_n wherefore_o this_o kind_n of_o remedy_n however_o otherwise_o conducible_a to_o health_n be_v scrupulous_o forbid_v to_o all_o marry_a woman_n that_o desire_v child_n of_o which_o prohibition_n there_o be_v no_o reason_n as_o yet_o make_v out_o but_o only_a story_n relate_v of_o certain_a woman_n that_o have_v be_v barren_a have_v issue_n when_o it_o be_v as_o easy_a to_o enumerate_v more_o barren_a woman_n without_o issue_n and_o many_o other_o that_o have_v be_v fruitful_a with_o they_o and_o true_o i_o use_v to_o retort_v whenas_o there_o be_v no_o need_n of_o any_o other_o refute_v this_o as_o a_o chief_a argument_n against_o that_o opinion_n sect_n iii_o chap._n v._o of_o the_o disease_n of_o the_o skin_n and_o of_o their_o remedy_n after_o attractive_a remedy_n of_o the_o cuticula_fw-la and_o skin_n namely_o issue_n and_o blister_a medicine_n deliver_v before_o by_o a_o certain_a law_n of_o method_n we_o be_v induce_v to_o handle_v disease_n of_o those_o part_n and_o other_o kind_n of_o remedy_n of_o divers_a sort_n the_o true_a aetiology_n of_o which_o will_v afford_v matter_n of_o most_o pleasant_a as_o well_o as_o profitable_a speculation_n as_o for_o the_o fabric_n and_o use_n of_o those_o part_n cuticula_fw-la a_o description_n of_o the_o cuticula_fw-la it_o need_v not_o that_o i_o shall_v here_o repeat_v all_o thing_n already_o accurate_o describe_v and_o well_o know_v in_o book_n of_o anatomy_n it_o may_v suffice_v we_o to_o note_v concern_v the_o cuticula_fw-la that_o this_o outward_a skin_n be_v thin_a and_o dense_a without_o blood_n and_o without_o sense_n as_o destitute_a of_o vessel_n and_o fibre_n which_o cleave_v to_o the_o inward_a skin_n coner_n and_o defend_v it_o from_o outward_a injury_n this_o be_v every_o where_o full_a of_o pore_n into_o who_o orifice_n the_o vessel_n discharge_v sweat_n do_v open_a which_o malpighius_n view_v more_o accurate_o with_o a_o microscope_n a_o little_a before_o their_o gape_a or_o open_v affirm_v to_o be_v endue_v with_o little_a valve_n for_o the_o retain_v or_o free_a breat_v forth_o of_o sweat_n but_o i_o confess_v they_o lie_v hide_v to_o i_o the_o cuticula_fw-la be_v take_v away_o by_o fire_n or_o phaenigmon_n the_o skin_n appear_v naked_a skin_n of_o the_o skin_n and_o look_v red_a by_o reason_n of_o the_o sanguiferous_a vessel_n but_o this_o be_v a_o thick_a membrane_n as_o to_o its_o great_a part_n form_v of_o filament_n of_o vessel_n bring_v blood_n of_o nerve_n and_o of_o nervous_fw-fr fibres_fw-fr various_o interweave_v and_o complicate_v among_o themselves_o among_o which_o numerous_a glandule_n and_o lymphduct_n or_o vessel_n discharge_v sweat_n and_o vapour_n be_v thick_o interpose_v the_o substance_n hereof_o be_v relate_v to_o be_v double_a by_o most_o anatomist_n the_o outer_a be_v nervous_a the_o inner_a fleshy_a or_o rather_o glandulous_a for_o a_o example_n of_o which_o the_o rind_n of_o a_o orange_n be_v bring_v if_o the_o skin_n be_v view_v naked_a by_o a_o microscope_n by_o the_o renown_a malpighius_n observation_n feeling_n the_o piramidall_a papillae_fw-la the_o organ_n of_o feeling_n first_o there_o present_v itself_o a_o body_n in_o form_n of_o a_o net_n in_o who_o thick_a hole_n be_v contain_v not_o only_a passage_n of_o sweat_n but_o also_o very_a many_o teat_n in_o form_n of_o a_o pyramid_n rise_v out_o of_o the_o skin_n in_o parallel_a rank_n and_o pass_v into_o the_o cuticula_fw-la where_o be_v stretch_v out_o in_o length_n they_o be_v divide_v as_o it_o be_v into_o many_o little_a fibres_n which_o the_o same_o author_n have_v determine_v to_o be_v the_o sense_n of_o touch_v beside_o these_o the_o substance_n of_o the_o skin_n contain_v very_o many_o glandule_n by_o which_o mean_v the_o lympha_fw-la or_o watery_a matter_n be_v carry_v by_o the_o lymphduct_n or_o excretory_a vessel_n out_o of_o the_o artery_n to_o the_o pore_n skin_n the_o pore_n and_o glandule_n of_o the_o skin_n for_o indeed_o the_o most_o accurate_a stenon_n have_v observe_v that_o its_o glandule_n lie_v under_o every_o poor_a which_o become_v either_o great_a or_o lesser_a according_a to_o the_o use_n of_o sweat_v the_o sweat_n or_o vapour_n continual_o stream_v out_o of_o these_o by_o the_o excretory_a vessel_n avoid_v the_o excrement_n do_v moisten_v the_o nervous_a teat_n in_o their_o passage_n lest_o perchance_o they_o shall_v grow_v dry_a as_o to_o the_o pore_n or_o passage_n of_o sweat_n lesser_a the_o pore_n twofold_a great_a and_o lesser_a they_o be_v discover_v by_o a_o microscope_n to_o be_v of_o two_o kind_n viz._n the_o great_a in_o most_o of_o which_o the_o root_n of_o the_o hair_n be_v implant_v and_o by_o interspace_n on_o both_o side_n of_o each_o wrinkle_n of_o the_o skin_n be_v dispose_v in_o a_o parallel_n rank_n or_o second_o they_o be_v the_o lesser_a pore_n which_o be_v numberless_a do_v fill_v up_o all_o the_o space_n between_o the_o former_a in_o most_o thick_a punctum_n or_o prick_n for_o indeed_o the_o whole_a skin_n with_o its_o wrinkle_n appear_v like_o a_o field_n furrow_v by_o a_o blow_n and_o after_o ward_n harrow_v with_o the_o rank_n turn_v or_o rather_o oblique_a so_o that_o its_o ground_n be_v eminent_a above_o the_o surrow_n of_o either_o kind_n there_o remain_v in_o its_o plain_a figure_n very_o much_o of_o a_o rhomboidal_a or_o a_o diamond-fashion_n skin_n the_o wrinkle_n and_o furrow_n of_o the_o skin_n and_o according_o as_o those_o furrow_n with_o their_o bank_n or_o flatte_n be_v either_o short_a and_o less_o or_o deep_a and_o great_a the_o texture_n of_o the_o skin_n appear_v either_o delicate_a and_o thin_a or_o thick_a and_o course_n this_o kind_n of_o constitution_n although_o it_o be_v most_o owe_v to_o one_o birth_n and_o to_o the_o primogenial_a grow_v together_o of_o the_o humour_n be_v however_o manifold_o alter_v by_o reason_n of_o the_o various_a accident_n of_o the_o ensue_a life_n a_o more_o gross_a diet_n difficult_a labour_n injury_n of_o air_n skin_n from_o whence_o the_o roughness_n or_o fineness_n of_o the_o skin_n and_o chief_o excess_n either_o of_o heat_n or_o cold_a render_v a_o skin_n more_o rough_a also_o contrariwise_o a_o nice_a and_o delicate_a education_n render_v its_o tone_n more_o fine_a and_o soft_a that_o the_o skin_n may_v become_v more_o neat_a smooth_a and_o equal_a it_o avail_v much_o that_o all_o its_o pore_n be_v fill_v with_o a_o benign_a mild_a and_o unctuous_a humour_n for_o so_o while_o all_o its_o pore_n become_v full_a pore_n depend_v much_o on_o the_o humour_n fill_v the_o pore_n and_o extend_v the_o level_n of_o the_o whole_a skin_n appear_v more_o smooth_a notwithstanding_o if_o a_o vicious_a humour_n furnish_v those_o pore_n or_o the_o benign_a humour_n that_o be_v in_o they_o be_v too_o much_o exhaust_v for_o that_o cause_n the_o skin_n will_v become_v rough_a and_o full_a of_o wrinkle_n wherefore_o if_o any_o endow_v with_o a_o most_o soft_a and_o even_a skin_n shall_v wet_v their_o hand_n in_o a_o soap_n lather_n lie_v or_o limewater_n or_o also_o for_o some_o time_n in_o warm_a blood_n present_o the_o furrow_n and_o wrinkle_n will_v grow_v great_a and_o deep_a the_o saline_a humour_n be_v draw_v out_o by_o the_o other_o salt_n out_o of_o the_o pore_n wherefore_o more_o delicate_a woman_n scrupulous_o decline_v wash_v with_o soap_n or_o any_o other_o thing_n that_o