the_o disease_n it_o be_v good_a for_o infallible_o and_o in_o all_o person_n that_o take_v it_o for_o i_o confess_v i_o never_o yet_o meet_v with_o any_o such_o remedy_n nor_o do_v i_o by_o specific_a understand_v a_o medicine_n that_o almost_o like_o a_o charm_n work_v only_o by_o some_o latent_fw-la and_o unaccountable_a property_n without_o the_o assistance_n of_o any_o know_a quality_n as_o purgative_n diuretic_n sudorific_a etc._n etc._n to_o be_v find_v in_o other_o medicine_n but_o by_o specific_a i_o mean_v in_o this_o discourse_n such_o a_o medicine_n as_o very_o often_o if_o not_o most_o common_o do_v very_o considerable_o and_o better_a than_o ordinary_a medicine_n relieve_v the_o patient_n whether_o by_o quite_o cure_v or_o much_o lessen_v his_o disease_n and_o which_o act_n principal_o upon_o the_o account_n of_o some_o property_n or_o peculiar_a virtue_n so_o that_o if_o it_o have_v any_o manifest_a quality_n that_o be_v friendly_a yet_o the_o good_a it_o do_v be_v great_a than_o can_v reasonable_o be_v ascribe_v to_o the_o degree_n it_o have_v of_o that_o manifest_a quality_n as_o hot_a cold_a bitter_a sudorific_a etc._n etc._n there_o be_v two_o grand_a question_n that_o may_v be_v propose_v about_o the_o specific_a virtue_n ascribe_v to_o medicine_n the_o first_o be_v whether_o there_o be_v real_o any_o such_o and_o the_o second_o whether_o if_o there_o be_v the_o mechanical_a hypothesis_n can_v be_v accommodate_v to_o they_o the_o former_a of_o these_o question_n may_v admit_v of_o a_o double_a sense_n for_o it_o may_v be_v propose_v with_o respect_n either_o to_o the_o present_a measure_n of_o our_o knowledge_n or_o to_o those_o further_a attainment_n that_o in_o future_a time_n man_n may_v arrive_v at_o in_o the_o latter_a of_o these_o sense_n to_o dispatch_v first_o the_o consideration_n of_o that_o i_o shall_v not_o presume_v to_o maintain_v without_o restriction_n either_o part_n of_o the_o question_n for_o i_o do_v not_o only_a hope_n but_o be_o apt_a to_o think_v that_o in_o time_n the_o industry_n and_o sagacity_n of_o man_n will_v be_v able_a to_o discover_v intelligible_a cause_n of_o most_o of_o those_o quality_n that_o now_o pass_v for_o occult_a and_o among_o they_o of_o many_o of_o the_o specific_a virtue_n ascribe_v to_o medicine_n and_o yet_o on_o the_o other_o side_n i_o much_o fear_v that_o man_n will_v not_o be_v successful_a in_o trace_v out_o the_o true_a and_o immediate_a cause_n of_o those_o good_a effect_n of_o some_o remedy_n that_o depend_v upon_o such_o fine_a and_o uncommon_a texture_n and_o such_o latent_fw-la and_o odd_o guide_v motion_n as_o fall_v not_o under_o our_o sense_n tho'_o perhaps_o assist_v by_o instrument_n which_o conjecture_n will_v appear_v the_o less_o improbable_a if_o we_o consider_v those_o admirable_a idiosyncrasiae_n or_o peculiarity_n of_o disposition_n whereof_o the_o book_n of_o eminent_a writer_n afford_v we_o many_o instance_n to_o who_o number_n i_o can_v upon_o my_o own_o observation_n add_v several_a if_o i_o think_v it_o needful_a and_o tho'_o i_o be_o not_o ignorant_a that_o some_o of_o these_o may_v be_v plausible_o account_v for_o as_o that_o of_o some_o man_n aversion_n to_o cheese_n or_o to_o cat_n yet_o i_o do_v not_o think_v that_o the_o like_a explication_n can_v be_v extend_v to_o some_o other_o that_o may_v be_v name_v if_o it_o be_v here_o pertinent_a to_o discuss_v that_o thorough_o as_o to_o the_o former_a sense_n of_o the_o question_n late_o propound_v i_o confess_v myself_o very_o amiable_a to_o the_o affirmative_a as_o far_o as_o i_o can_v judge_v by_o those_o write_n of_o physician_n i_o have_v have_v occasion_n to_o peruse_v which_o limitation_n i_o add_v because_o i_o will_v not_o derogate_v from_o the_o knowledge_n of_o particular_a person_n who_o in_o so_o learned_a and_o inquisitive_a a_o age_n may_v be_v arrive_v at_o far_o great_a attainment_n than_o those_o physician_n have_v do_v that_o have_v entertain_v the_o public_a about_o the_o occult_a and_o specific_a quality_n of_o medicine_n i_o know_v there_o have_v be_v and_o still_o be_v dogmatical_a physician_n that_o upon_o the_o principle_n as_o they_o pretend_v of_o the_o school-philosophy_n reject_v all_o medicinal_a virtue_n that_o they_o think_v not_o reducible_a to_o manifest_v quality_n but_o of_o such_o galen_n somewhere_o just_o complain_v that_o they_o either_o deny_v matter_n of_o fact_n or_o assign_v very_o incompetent_a cause_n of_o the_o effect_n they_o pretend_v to_o explain_v and_o for_o my_o part_n i_o be_o so_o far_o from_o believe_v these_o man_n capable_a of_o give_v sufficient_a reason_n of_o the_o more_o hide_a property_n of_o medicine_n that_o i_o be_o not_o apt_a to_o think_v they_o able_a by_o their_o principle_n to_o give_v clear_a and_o particular_a explication_n even_o of_o the_o more_o easy_a and_o familiar_a virtue_n of_o simple_n i_o be_o therefore_o dispose_v to_o think_v that_o in_o the_o sense_n former_o deliver_v of_o the_o term_n specific_a medicine_n there_o be_v some_o remedy_n that_o deserve_v that_o name_n to_o this_o opinion_n i_o have_v be_v lead_v by_o several_a reason_n and_o first_o to_o begin_v with_o the_o least_o weighty_a it_o have_v the_o suffrage_n of_o many_o learned_a physician_n both_o ancient_a and_o modern_a and_o particular_o that_o of_o galen_n himself_o in_o several_a place_n of_o his_o work_n and_o i_o remember_v that_o treat_v of_o a_o specific_a remedy_n against_o the_o bite_n of_o a_o mad_a dog_n which_o virtue_n he_o ascribe_v to_o a_o occult_a quality_n or_o as_o he_o speak_v to_o the_o propriety_n of_o the_o whole_a substance_n 11._o he_o take_v occasion_n to_o promise_v that_o he_o will_v write_v a_o book_n of_o thing_n that_o operate_v upon_o that_o account_n which_o book_n if_o it_o have_v escape_v with_o his_o other_o work_n for_o he_o elsewhere_o cite_v it_o as_o have_v write_v it_o will_v probable_o have_v furnish_v we_o with_o several_a thing_n to_o strengthen_v our_o opinion_n and_o tho'_o in_o matter_n philosophical_a i_o be_o little_o sway_v by_o mere_a authority_n yet_o the_o concurrent_a suffrage_n of_o many_o eminent_a physician_n may_v in_o this_o controversy_n be_v the_o more_o considerable_a because_o most_o of_o they_o be_v note_v practitioner_n have_v opportunity_n to_o observe_v whether_o or_o no_o any_o remedy_n deserve_v the_o name_n of_o specific_v and_o their_o testimony_n be_v in_o our_o case_n the_o more_o to_o be_v regard_v because_o physician_n especial_o famous_a one_o be_v not_o wont_a to_o be_v willing_a to_o acknowledge_v that_o there_o be_v effect_n which_o fall_v under_o the_o cognisance_n of_o their_o art_n whereof_o they_o can_v give_v the_o cause_n my_o next_o inducement_n to_o admit_v specific_v be_v found_v upon_o parity_n of_o reason_n for_o it_o be_v manifest_a that_o there_o be_v divere_fw-la formidable_a malady_n that_o be_v produce_v by_o inconsiderable_a quantity_n of_o poison_n that_o have_v not_o be_v discover_v to_o produce_v such_o great_a and_o dismal_a effect_n by_o any_o manifest_a quality_n whether_o first_o second_o or_o three_o as_o medical_n author_n i_o doubt_v not_o over_o accurate_o distinguish_v they_o on_o this_o occasion_n i_o shall_v add_v a_o very_a odd_a accident_n about_o which_o i_o be_v advise_v with_o by_o a_o expert_a oculist_n very_o soon_o after_o it_o happen_v the_o case_n be_v this_o a_o man_n lie_v somewhat_o long_o in_o bed_n in_o the_o morning_n and_o chance_v as_o he_o lie_v upon_o his_o back_n to_o cast_v up_o his_o eye_n to_o the_o tester_n see_v a_o great_a spider_n that_o stand_v still_o just_a over_o his_o face_n wherefore_o have_v reproach_v his_o wife_n who_o happen_v to_o be_v in_o the_o room_n with_o gross_a negligence_n she_o take_v a_o broom_n and_o strike_v it_o upon_o the_o upper_a part_n of_o the_o tester_n to_o beat_v down_o the_o spider_n but_o the_o animal_n hold_v so_o fast_o with_o his_o foot_n that_o she_o miss_v her_o aim_n and_o he_o whether_o fright_v or_o irritate_v by_o this_o rude_a shake_n let_v fall_n upon_o the_o man_n that_o be_v stare_v at_o it_o to_o see_v what_o will_v happen_v a_o drop_n of_o liquor_n that_o light_v direct_o upon_o one_o of_o his_o open_a eye_n but_o find_v no_o heat_n nor_o sharpness_n ensue_v but_o rather_o a_o very_a sensible_a coldness_n he_o make_v nothing_o of_o it_o but_z rose_z and_o put_v on_o his_o clothes_n but_o present_o after_o happen_v to_o rub_v with_o his_o finger_n the_o other_o eye_n he_o be_v sad_o surprise_v to_o find_v himself_o sudden_o benight_a and_o call_v for_o assistance_n he_o find_v that_o the_o eye_n which_o the_o spider_n have_v let_v fall_v something_o on_o tho'_o no_o change_n be_v note_v in_o it_o by_o the_o bystander_n be_v total_o deprive_v of_o sight_n upon_o which_o score_n he_o repair_v to_o the_o above_o mention_a oculist_n but_o whether_o he_o afterward_o recover_v his_o sight_n
lusty_a animal_n the_o aptness_n then_o that_o the_o corpuscle_n of_o the_o specific_a may_v give_v the_o blood_n or_o other_o liquor_n that_o convey_v they_o to_o act_v as_o a_o appropriate_v menstruum_fw-la upon_o the_o peculiarly_a modify_v matter_n that_o obstruct_v or_o otherwise_o disaffect_v the_o liver_n for_o instance_n may_v enable_v the_o remedy_n to_o be_v very_o helpful_a to_o that_o part_n by_o prepare_v the_o molest_a matter_n for_o expulsion_n but_o it_o may_v also_o succour_v the_o same_o part_n in_o another_o way_n for_o in_o the_o second_o place_n it_o may_v so_o work_v upon_o the_o fibre_n and_o stable_a portion_n of_o the_o part_n affect_v as_o both_o to_o enable_v it_o and_o excite_v it_o to_o free_v its_o self_n from_o its_o enemy_n for_o it_o may_v give_v firmness_n and_o strength_n to_o the_o fibre_n of_o the_o part_n it_o may_v also_o contemperate_a or_o correct_v the_o immoderate_a heat_n coldness_n etc._n etc._n of_o it_o it_o may_v mortify_v the_o acid_n or_o other_o incongruous_a particle_n that_o be_v lodge_v in_o the_o minute_n interval_n of_o the_o stable_a part_n end_v perhaps_o even_o in_o the_o pore_n of_o the_o fibre_n it_o may_v appease_v its_o convulsion_n cramp_n or_o other_o inordinate_a motion_n that_o hinder_v it_o from_o daily_o execute_v its_o proper_a function_n it_o may_v relax_v or_o widen_v the_o pore_n according_a to_o the_o exigency_n of_o the_o work_n to_o be_v perform_v and_o have_v thus_o by_o mean_n of_o its_o friendly_a corpuscle_n prepare_v the_o matter_n to_o be_v expel_v and_o dispose_v the_o part_n to_o expel_v it_o it_o may_v then_o also_o excite_v the_o part_n to_o do_v its_o office_n by_o irritate_v the_o fibre_n or_o motive_n organ_n or_o stimulate_v they_o to_o disburden_v the_o part_n of_o the_o matter_n that_o offend_v it_o as_o a_o very_a small_a do_v of_o cantharides_n be_v know_v by_o this_o way_n of_o irritation_n to_o be_v capable_a of_o make_v the_o bladder_n forcible_o though_o not_o safe_o discharge_v itself_o of_o urine_n and_o with_o that_o oftentimes_o expel_v the_o sand_n and_o gravel_n or_o lesser_a stone_n and_o the_o excrementitious_a slime_n that_o molest_v it_o before_o and_o this_o instance_n may_v be_v of_o use_n to_o we_o in_o answer_v that_o which_o we_o former_o note_v to_o be_v so_o confident_o urge_v by_o the_o rejecter_n of_o specific_a medicine_n for_o here_o we_o have_v a_o medicine_n though_o a_o dangerous_a one_o who_o corpuscle_n have_v such_o a_o peculiar_a reference_n to_o the_o bladder_n and_o urinary_a organ_n that_o though_o be_v get_v into_o the_o mass_n of_o blood_n they_o be_v carry_v by_o it_o indiscriminate_o to_o other_o part_n of_o the_o body_n as_o well_o as_o to_o these_o yet_o oftentimes_o without_o manifest_o disaffect_v the_o rest_n they_o exceed_o irritate_fw-la the_o bladder_n and_o determine_v it_o to_o the_o excretion_n of_o what_o it_o contain_v and_o whereas_o it_o may_v be_v object_v that_o the_o first_o of_o the_o three_o way_n by_o which_o we_o note_v that_o a_o particular_a part_n may_v be_v succour_v by_o a_o specific_a seem_v contrary_a to_o the_o second_o the_o former_a tend_v to_o corroborate_v the_o part_n and_o the_o late_a to_o relax_v and_o irritate_fw-la it_o i_o answer_v two_o thing_n one_o that_o since_o the_o part_n may_v be_v sometime_o in_o a_o natural_a and_o sometime_o in_o a_o preternatural_a state_n in_o the_o former_a a_o medicine_n may_v deserve_v the_o name_n of_o friendly_a or_o appropriate_v because_o it_o keep_v it_o sound_a which_o be_v most_o proper_o do_v by_o strengthen_v it_o and_o in_o the_o late_a it_o may_v merit_v the_o title_n of_o a_o specific_a because_o it_o help_v to_o restore_v it_o to_o a_o state_n of_o soundness_n and_o the_o other_o that_o though_o to_o effect_v this_o recovery_n it_o be_v often_o very_o expedient_a if_o not_o necessary_a that_o the_o medicine_n procure_v a_o evacuation_n of_o some_o matter_n that_o offend_v it_o yet_o that_o evacuation_n itself_o be_v often_o much_o promote_v and_o facilitated_a by_o stengthen_v the_o part_n so_o as_o to_o enable_v it_o to_o disburden_v itself_o and_o the_o same_o medicine_n may_v contain_v and_o communicate_v to_o the_o blood_n corpuscle_n of_o such_o differ_a shape_n size_n motion_n &c._n &c._n as_o may_v at_o least_o successive_o relieve_v the_o part_n by_o both_o these_o way_n as_o physician_n observe_v that_o rhubarb_n do_v not_o only_o by_o its_o fine_a and_o laxative_a part_n purge_v the_o liver_n of_o choler_n but_o by_o its_o more_o earthy_a astringent_a corpuscle_n strengthen_v the_o tone_n of_o that_o part_n what_o far_o belong_v to_o the_o illustration_n of_o this_o matter_n will_v be_v meet_v with_o in_o due_a place_n on_o this_o occasion_n it_o will_v not_o be_v impertinent_a to_o add_v that_o in_o some_o case_n this_o very_a corroboration_n of_o a_o distemper_a part_n may_v restore_v it_o to_o soundness_n there_o be_v some_o disease_n of_o such_o a_o nature_n that_o they_o be_v if_o i_o may_v so_o speak_v almost_o always_o in_o fieri_fw-la that_o be_v they_o can_v not_o continue_v to_o subsist_v in_o the_o affect_a part_n unless_o through_o its_o debility_n and_o the_o consequence_n of_o it_o it_o be_v subject_a to_o admit_v from_o time_n to_o time_n fresh_a recruit_n of_o peccant_a matter_n to_o foment_n the_o malady_n and_o in_o such_o distemper_n if_o the_o structure_n and_o tone_n of_o the_o part_n be_v reestablish_v by_o the_o operation_n of_o the_o specific_a medicine_n it_o be_v acquire_v vigour_n will_v enable_v it_o to_o resist_v the_o ingress_n of_o new_a supply_n of_o peccant_a matter_n and_o to_o turn_v they_o off_o into_o the_o mass_n of_o blood_n to_o be_v thence_o discharge_v by_o the_o common_a shore_n of_o the_o body_n whilst_o in_o the_o mean_a time_n nature_n will_v be_v able_a by_o degree_n to_o subdue_v dissipate_v or_o otherwise_o dispose_v of_o that_o comparative_o little_a portion_n of_o peccant_a matter_n that_o be_v lodge_v in_o the_o disease_a part._n we_o have_v not_o in_o this_o paper_n give_v any_o example_n of_o the_o peculiar_a respect_n of_o a_o specific_a medicine_n to_o a_o determinate_a disaffect_v part_n that_o one_o will_v think_v so_o incredible_a as_o that_o a_o heavy_a stony_a substance_n be_v in_o no_o great_a quantity_n take_v in_o at_o die_v mouth_n shall_v manifest_o contribute_v to_o the_o cure_n of_o a_o break_a bone_n in_o one_o of_o the_o limb_n as_o the_o leg_n or_o the_o hand_n and_o yet_o not_o to_o urge_v the_o testimony_n of_o chemical_a writer_n i_o remember_v a_o german_a physician_n that_o be_v famous_a for_o notable_a cure_n relate_v wonder_n to_o i_o of_o the_o efficacy_n of_o that_o stone_n grow_v in_o his_o country_n which_o from_o its_o effect_n they_o call_v osteocolla_n especial_o if_o it_o be_v improve_v by_o a_o skilful_a preparation_n which_o he_o communicate_v to_o i_o but_o i_o have_v not_o opportunity_n to_o make_v trial_n of_o it_o but_o without_o preparation_n the_o judicious_a and_o long_o experience_a chirurgeon_n fabricius_n hildanus_n much_o commend_v upon_o his_o own_o observation_n a_o single_a dram_n of_o it_o fine_o powder_a for_o the_o breed_n of_o a_o callus_fw-la to_o solder_v together_o the_o part_n of_o a_o break_a bone_n insomuch_o that_o he_o give_v a_o caution_n to_o use_v it_o but_o spare_o in_o young_a and_o vigorous_a patient_n lest_o it_o breed_v too_o great_a a_o callus_fw-la of_o which_o he_o give_v a_o notable_a instance_n and_o the_o like_a caution_n be_v inculcate_v to_o i_o from_o experience_n by_o the_o late_o mention_v german_n doctor_n because_o otherwise_o he_o say_v his_o preparation_n will_v in_o such_o person_n make_v the_o medicine_n generate_v a_o callus_fw-la too_o soon_o and_o too_o great_a proposition_n v._n sometime_o a_o specific_a medicine_n may_v do_v its_o work_n by_o produce_v in_o the_o mass_n of_o blood_n such_o a_o disposition_n as_o may_v enable_v nature_n by_o correct_v expel_v or_o other_o fit_a way_n to_o surmount_v the_o morbific_a matter_n or_o other_o cause_n of_o the_o disease_n he_o that_o shall_v heedful_o observe_v the_o practice_n of_o divers_a learned_a and_o successful_a modern_a physician_n may_v discern_v that_o many_o if_o not_o most_o of_o their_o prescription_n be_v found_v upon_o a_o supposition_n that_o a_o great_a part_n of_o the_o disease_n incident_a to_o man_n body_n and_o the_o recovery_n from_o they_o depend_v main_o upon_o the_o vitiate_a constitution_n of_o the_o blood_n and_o the_o restore_n it_o to_o a_o sound_a condition_n this_o advantageous_a change_n of_o the_o blood_n may_v be_v effect_v by_o a_o specific_a several_a way_n sometime_o separately_z and_o sometime_o joint_o and_o particular_o by_o those_o that_o follow_v 1._o that_o which_o i_o shall_v first_o name_n be_v by_o furnish_v the_o blood_n with_o some_o sort_n of_o active_a corpuscle_n that_o it_o need_v to_o
and_o consequent_o the_o heart_n one_o may_v be_v allow_v to_o suppose_v that_o the_o corpuscle_n of_o a_o specific_a may_v either_o dissolve_v some_o particle_n they_o meet_v with_o in_o the_o heart_n by_o which_o that_o noble_a viscus_fw-la be_v by_o irritation_n or_o otherwise_o disturb_v in_o the_o regularity_n of_o its_o dilatation_n and_o contraction_n or_o so_o corroborate_v the_o fibre_n or_o motive_n organ_n of_o it_o as_o to_o dispose_v it_o to_o moderate_v the_o circulation_n of_o the_o blood_n that_o pass_v through_o it_o in_o the_o most_o advantageous_a way_n and_o that_o the_o disposition_n of_o the_o heart_n even_o when_o man_n have_v no_o sense_n of_o it_o in_o the_o part_n itself_o may_v be_v of_o moment_n as_o to_o health_n and_o sickness_n will_v appear_v credible_a if_o we_o reflect_v on_o two_o thing_n one_o that_o a_o live_a human_a body_n be_v not_o a_o mere_a aggregate_v of_o flesh_n bones_o etc._n etc._n but_o a_o exquisite_o contrive_v and_o very_o sensible_a engine_n who_o part_n be_v easy_o set_v a_o work_n by_o proper_a though_o very_a minute_n agent_n and_o may_v by_o their_o action_n upon_o one_o another_o perform_v far_o great_a thing_n than_o can_v be_v expect_v from_o the_o bare_a energy_n of_o the_o agent_n that_o first_o put_v they_o into_o motion_n the_o second_o which_o suppose_v the_o first_o that_o the_o disposition_n of_o the_o heart_n be_v though_o perhaps_o insensible_o change_v it_o may_v produce_v a_o notable_a alteration_n in_o the_o motion_n of_o the_o blood_n and_o its_o passage_n through_o the_o heart_n in_o point_n of_o quantity_n celerity_n or_o both_o how_o much_o this_o change_n in_o the_o circulation_n may_v in_o many_o case_n conduce_v to_o sickness_n or_o recovery_n may_v partly_o appear_v by_o the_o effect_n of_o vehement_a or_o durable_a passion_n of_o the_o mind_n as_o it_o be_v observe_v that_o in_o a_o deep_a sorrow_n which_o do_v in_o a_o manner_n straiten_v the_o passage_n of_o the_o heart_n the_o blood_n be_v too_o spare_o dispense_v the_o enliven_a spirit_n be_v not_o generate_v plentiful_o enough_o and_o beside_o other_o bad_a effect_n of_o this_o state_n of_o the_o heart_n the_o blood_n be_v so_o dispirited_a as_o in_o these_o part_n of_o europe_n to_o dispose_v the_o body_n to_o the_o scurvy_a which_o do_v either_o produce_v or_o irritate_fw-la divers_a other_o malady_n we_o see_v also_o that_o the_o passion_n of_o shame_n do_v oftentimes_o sudden_o alter_v the_o motion_n of_o the_o blood_n and_o make_v it_o swell_v the_o little_a vessel_n that_o lie_v under_o the_o cuticula_fw-la of_o the_o face_n and_o sometime_o other_o part_n as_o be_v very_o manifest_a in_o young_a maid_n and_o other_o person_n of_o a_o delicate_a complexion_n the_o white_a part_n of_o who_o face_n in_o blush_a turn_n red._n the_o like_a effect_n i_o have_v see_v produce_v by_o a_o great_a and_o sudden_a joy_n and_o though_o grief_n which_o be_v the_o opposite_a passion_n to_o it_o have_v be_v usual_o take_v notice_n of_o as_o a_o thing_n that_o dead_v the_o appetite_n to_o meat_n yet_o so_o much_o do_v depend_v upon_o a_o well_o moderate_v transmission_n of_o the_o blood_n that_o it_o have_v be_v observe_v in_o divers_a person_n and_o i_o have_v know_v a_o eminent_a instance_n of_o it_o that_o great_a joy_n have_v very_o much_o lessen_v hunger_n of_o which_o effect_n mr._n des_n cartes_n ingenious_o attempt_v to_o derive_v the_o cause_n from_o the_o varied_a dilatation_n and_o motion_n of_o the_o heart_n and_o it_o seem_v not_o absurd_a to_o conceive_v that_o such_o like_a motion_n may_v be_v cause_v by_o the_o corpuscle_n of_o a_o specific_a medicine_n which_o by_o affect_v the_o fibre_n of_o the_o heart_n after_o the_o like_a manner_n that_o joy_n be_v wont_a to_o do_v may_v produce_v in_o it_o such_o friendly_a dilatation_n and_o contraction_n as_o be_v wont_a to_o flow_v from_o the_o agreeable_a passion_n in_o favour_n of_o which_o conjecture_n i_o shall_v take_v notice_n that_o a_o lady_n of_o my_o acquaintance_n have_v complain_v to_o i_o that_o the_o smell_n of_o perfume_a glove_n be_v wont_a to_o make_v the_o blood_n fly_v to_o her_o face_n and_o continue_v there_o for_o a_o great_a while_n give_v it_o such_o a_o colour_n as_o if_o shame_n or_o joy_n have_v cover_v it_o with_o blush_n and_o the_o like_a she_o say_v she_o have_v observe_v in_o other_o of_o her_o sex_n but_o have_v in_o another_o tract_n speak_v of_o the_o power_n of_o the_o passion_n of_o the_o mind_n to_o alter_v the_o state_n of_o the_o body_n by_o produce_v change_n in_o the_o blood_n that_o be_v transmit_v through_o the_o heart_n what_o have_v be_v say_v may_v now_o suffice_v to_o make_v it_o credible_a that_o a_o specific_a remedy_n by_o peculiarly_a befriend_v the_o heart_n may_v contribute_v much_o to_o introduce_v or_o re-establish_a a_o healthy_a crasis_n in_o the_o blood_n and_o this_o be_v thus_o rectify_v and_o invigorate_v itself_o may_v both_o befriend_v the_o body_n in_o general_n and_o conduce_v to_o the_o removal_n of_o some_o particular_a disease_n by_o strengthen_v and_o perhaps_o too_o exciting_a the_o particular_a part_n in_o which_o the_o peccant_a matter_n reside_v to_o subdue_v or_o expel_v that_o which_o it_o already_o harbour_v and_o resist_v any_o accession_n of_o more_o and_o the_o blood_n be_v itself_o well_o constitute_v as_o well_o as_o the_o stable_n part_v corroborate_v the_o specific_a medicine_n that_o produce_v these_o good_a effect_n may_v be_v say_v to_o cure_v though_o perhaps_o but_o slow_o divers_a particular_a disease_n such_o as_o those_o elsewhere_o mention_v in_o this_o paper_n which_o to_o continue_v must_v be_v frequent_o supply_v with_o vicious_a matter_n by_o the_o circulate_v blood_n experiment_n vi._n sometime_o a_o specific_a remedy_n may_v unite_v its_o particle_n with_o those_o of_o the_o peccant_a matter_n and_o with_o they_o constitute_v a_o neutrum_fw-la quid_fw-la that_o may_v be_v easy_o proscribe_v or_o not_o necessary_a to_o be_v expel_v this_o i_o take_v to_o be_v one_o of_o the_o most_o proper_a and_o genuine_a way_n of_o do_v good_a that_o belong_v to_o a_o specific_a medicine_n as_o such_o because_o in_o this_o operation_n a_o effect_n be_v produce_v either_o without_o the_o assistance_n or_o beyond_o the_o mere_a power_n of_o the_o manifest_a quality_n as_o physician_n call_v they_o of_o the_o remedy_n and_o the_o cure_n or_o relief_n the_o patient_n find_v be_v usual_o attain_v without_o violence_n and_o without_o torment_v or_o much_o disorder_v he_o this_o way_n of_o work_v of_o a_o specific_a medicine_n be_v of_o near_a affinity_n with_o one_o or_o two_o of_o those_o former_o discourse_v of_o but_o yet_o these_o way_n differ_v in_o some_o thing_n as_o may_v be_v gather_v by_o the_o sequel_n of_o §_o this_o discourse_n §_o sometime_o when_o a_o certain_a kind_n of_o acid_n have_v impregnate_v the_o blood_n or_o lodge_v itself_o in_o some_o stable_a part_n as_o the_o liver_n spleen_n kidney_n etc._n etc._n the_o corpuscle_n of_o a_o specific_a may_v without_o any_o sensible_a luctation_n or_o conflict_n which_o usual_o happen_v when_o acid_n be_v mortify_a by_o sapid_a alkaly_n be_v so_o qualify_v as_o both_o to_o make_v coalition_n with_o the_o small_a part_n of_o the_o peccant_a acid_n and_o with_o they_o to_o constitute_v little_a concretion_n which_o differ_v from_o the_o minute_n part_v of_o the_o acid_n either_o in_o bulk_n figure_n solidity_n stifness_n motion_n or_o in_o two_o or_o more_o of_o these_o may_v be_v quite_o of_o another_o nature_n and_o of_o a_o much_o innocenter_n than_o the_o acid_n be_v before_o it_o be_v so_o correct_v of_o this_o we_o may_v be_v furnish_v with_o a_o notable_a illustration_n by_o what_o i_o have_v elsewhere_o take_v notice_n of_o about_o aqua_fw-la fortis_fw-la itself_o for_o as_o corrosive_a a_o menstruum_fw-la as_o that_o be_v yet_o by_o digest_v it_o and_o perhaps_o distil_v it_o too_o with_o a_o equal_a or_o rather_o double_a weight_n of_o ardent_a spirit_n i_o find_v the_o high_o acid_n liquor_n will_v be_v so_o change_v as_o not_o to_o retain_v any_o sensible_a corrosiveness_n and_o exchange_v its_o pierce_a stink_n and_o great_a acidity_n for_o a_o not_o only_o inoffensive_a but_o pleasant_a scent_n and_o a_o grateful_a and_o positive_o sweetish_a taste_n which_o bring_v into_o my_o mind_n the_o practice_n of_o a_o precedent_n of_o the_o famous_a london_n college_n who_o as_o himself_o tell_v i_o be_v wont_a to_o relieve_v a_o patient_n of_o very_o great_a quality_n in_o nephritick_n torment_n by_o give_v she_o a_o good_a do_v of_o a_o inflammable_a spirit_n but_o this_o upon_o the_o by_o i_o have_v elsewhere_o give_v a_o account_n of_o the_o effect_n of_o spirit_n of_o wine_n upon_o several_a other_o acid_n menstruum_n wherewith_o i_o mingle_v and_o digest_v it_o by_o which_o it_o may_v appear_v that_o it_o