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cause_n great_a know_v matter_n 2,542 5 5.1820 4 true
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ID Title Author Corrected Date of Publication (TCP Date of Publication) STC Words Pages
A33709 A physico medical essay concerning alkaly and acid so far as they have relation to the cause or cure of distempers : wherein is endeavoured to be proved that acids are not (as is generally and erroneously supposed) the cause of all or most distempers, but that alkalies are : together with an account of some distempers and the medicines with their preparations proper to be used in the cure of them : as also a short digression concerning specifick remedies / by John Colbatch. Colbatch, John, Sir, 1670-1729. 1696 (1696) Wing C5003; ESTC R26032 33,359 174

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they_o pretend_v the_o occasion_n of_o all_o the_o ill_a symptom_n that_o attend_v people_n in_o the_o smallpox_n now_o i_o can_v never_o hear_v of_o any_o one_o that_o by_o analyze_a the_o blood_n of_o person_n in_o the_o smallpox_n that_o can_v ever_o find_v the_o least_o footstep_n of_o acidity_n in_o it_o though_o on_o the_o contrary_a it_o do_v appear_v after_o many_o trial_n that_o the_o blood_n of_o such_o person_n do_v more_o abound_v with_o alkalious_a particle_n then_o that_o of_o sound_a people_n so_o by_o consequence_n the_o give_v of_o alkaly_n in_o this_o case_n must_v be_v at_o least_o superfluous_a if_o not_o high_o pernicious_a and_o as_o i_o have_v frequent_o observe_v and_o shall_v instance_n in_o some_o particular_n the_o cause_n of_o the_o smallpox_n common_a with_o most_o other_o fevor_n and_o acute_a distemper_n i_o
to_o what_o general_o do_v and_o where_o life_n lie_v at_o stake_n people_n can_v be_v too_o cautious_a but_o if_o the_o good_a old_a woman_n and_o nurse_n in_o spite_n of_o all_o that_o can_v be_v say_v will_v be_v still_o tamper_n i_o must_v needs_o say_v this_o that_o if_o my_o method_n be_v exact_o follow_v by_o every_o body_n from_o the_o beginning_n without_o any_o variation_n i_o very_o believe_v that_o there_o will_v not_o one_o in_o ten_o die_v that_o have_v former_o do_v by_o the_o use_n of_o alkaly_n and_o diaphoretick_n as_o i_o have_v before_o endeavour_v to_o explode_v the_o use_n of_o alkaly_n and_o to_o give_v my_o reason_n for_o so_o do_v so_o i_o shall_v now_o endeavour_v to_o give_v some_o reason_n for_o the_o method_n i_o take_v with_o the_o great_a use_n of_o acid_n in_o this_o case_n as_o i_o have_v before_o observe_v i_o judge_v the_o cause_n of_o the_o small_a pox_n to_o be_v from_o a_o intromission_n of_o heterogeneous_a or_o particle_n of_o a_o different_a nature_n and_o texture_n from_o the_o blood_n into_o it_o by_o the_o mean_n of_o which_o particle_n the_o blood_n be_v put_v into_o a_o very_a great_a hurry_n and_o disorder_n in_o order_n to_o throw_v off_o its_o enemy_n and_o that_o the_o place_n that_o nature_n design_n the_o discharge_n of_o these_o particle_n by_o to_o be_v the_o cutaneous_a gland_n now_o the_o inconvenience_n that_o i_o observe_v to_o attend_v the_o use_n of_o alkaly_n be_v the_o throw_v out_o of_o more_o pustles_a than_o nature_n design_v the_o destroy_n of_o the_o globule_n of_o the_o blood_n and_o a_o waste_n of_o too_o great_a a_o quantity_n of_o serum_fw-la i_o have_v before_o forget_v to_o mention_v one_o dismal_a effect_n of_o alkaly_n and_o diaphoretick_n and_o that_o be_v by_o destroy_v or_o break_v the_o globule_n of_o the_o blood_n instead_o of_o regular_a pustle_v be_v throw_v out_o to_o the_o surface_n of_o the_o skin_n the_o divide_a break_a globule_n be_v together_o with_o the_o morbific_a matter_n throw_v out_o as_o in_o the_o case_n of_o and_o so_o cause_v a_o erispelas_n or_o st._n anthony_n fire_n which_o seldom_o or_o never_o fail_v of_o prove_v fatal_a now_o i_o almost_o defy_v any_o one_o to_o say_v that_o he_o ever_o observe_v such_o symptom_n as_o these_o if_o acid_n be_v from_o the_o beginning_n use_v for_o acid_n be_v of_o that_o nature_n that_o they_o confirm_v the_o texture_n of_o the_o blood_n which_o be_v that_o red_a substance_n wherein_o be_v contain_v the_o byolyenium_n chyr_n byolyenium_n nou._n lum_o chyr_n or_o lamp_n of_o life_n by_o so_o do_v nature_n be_v capable_a of_o throw_v out_o the_o extraneous_a particle_n in_o a_o way_n suitable_a to_o it_o and_o without_o the_o inconvenience_n that_o attend_v the_o other_o method_n for_o the_o texture_n of_o the_o blood_n be_v confirm_v and_o move_v regular_o and_o natural_o in_o its_o proper_a channel_n the_o morbific_a particle_n be_v only_o throw_v out_o and_o such_o a_o quantity_n of_o serum_fw-la leave_v as_o be_v sufficient_a to_o supply_v the_o pustles_a and_o bring_v they_o to_o maturity_n without_o any_o danger_n of_o their_o flatue_n and_o the_o acrid_a matter_n be_v again_o absorb_v into_o the_o blood_n and_o cause_v secondary_a fever_n beside_o the_o globule_n of_o the_o blood_n be_v keep_v together_o unbroken_a there_o be_v not_o any_o danger_n of_o their_o be_v extravasated_a and_o cause_v those_o fatal_a purple_a spot_n nor_o of_o be_v throw_v out_o together_o with_o morbific_a matter_n and_o so_o cause_v a_o erisipelas_n or_o st._n anthony_n fire_n neither_o be_v hemoragy_n at_o the_o the_o nose_n bloody_a water_n etc._n etc._n in_o the_o least_o to_o be_v fear_v nor_o by_o be_v admit_v into_o the_o small_a meander_n of_o the_o brain_n to_o cause_n deliriums_n and_o those_o other_o symptom_n that_o attend_v it_o i_o may_v expatiate_v upon_o continue_a fever_n and_o some_o other_o acute_a distemper_n but_o that_o will_v be_v to_o be_v guilty_a of_o tautology_n for_o i_o assign_v but_o one_o general_a cause_n of_o they_o though_o i_o own_o that_o the_o extraneous_a particle_n cause_v they_o may_v be_v somewhat_o different_a and_o according_a to_o the_o different_a size_n of_o the_o extraneous_a particle_n the_o part_n affect_v may_v be_v different_a as_o in_o the_o smallpox_n the_o size_n of_o the_o particle_n be_v such_o as_o to_o fit_v they_o to_o be_v throw_v out_o by_o the_o cutaneous_a gland_n to_o the_o surface_n of_o the_o skin_n in_o other_o fever_n they_o be_v throw_v out_o sometime_o one_o way_n sometime_o another_o according_a to_o their_o size_n for_o instance_n sometime_o they_o be_v throw_v out_o by_o critical_a sweat_v sometime_o by_o urine_n sometime_o by_o the_o gland_n of_o the_o mouth_n in_o spit_v and_o so_o on_o according_a to_o the_o different_a disposition_n of_o the_o particle_n cause_v the_o distemper_n be_v fit_v to_o be_v discharge_v through_o the_o pore_n of_o different_a part_n and_o which_o ever_o way_n we_o find_v nature_n incline_v to_o do_v her_o work_n we_o must_v assist_v she_o in_o it_o but_o not_o spur_v she_o on_o unless_o she_o be_v too_o sluggish_a but_o must_v not_o upon_o any_o account_n whatsoever_o hinder_v or_o thwart_v she_o in_o her_o operation_n in_o most_o continue_a fever_n i_o have_v find_v alkaly_n equal_o pernicious_a as_o in_o the_o smallpox_n and_o acid_v equal_o advantageous_a the_o which_o i_o shall_v instance_n in_o one_o or_o two_o particular_n after_o i_o come_v out_o of_o flanders_n last_o year_n be_v ninety_o four_o have_v discourse_v with_o a_o certain_a physician_n about_o a_o fever_n that_o have_v that_o summer_n rage_v in_o london_n and_o of_o which_o many_o die_v he_o tell_v i_o that_o when_o he_o find_v his_o patient_n under_o such_o and_o such_o circumstance_n that_o he_o as_o much_o give_v they_o up_o for_o dead_a as_o if_o a_o dagger_n be_v run_v through_o their_o heart_n i_o ask_v he_o what_o those_o symptom_n be_v that_o render_v his_o patient_n circumstance_n to_o be_v so_o very_o dangerous_a he_o reply_v that_o when_o he_o find_v they_o delirious_a and_o have_v spasme_n and_o convulsion_n of_o the_o nerve_n i_o inquire_v of_o he_o what_o medicine_n he_o give_v he_o tell_v i_o a_o composition_n of_o gascon_n powder_n virginian_a snake_n root_n etc._n etc._n which_o be_v what_o he_o sole_o rely_v on_o and_o which_o be_v the_o same_o or_o of_o the_o same_o nature_n with_o what_o be_v general_o give_v in_o those_o case_n i_o ask_v he_o whether_o he_o have_v never_o find_v his_o medicine_n serviceable_a to_o he_o he_o ingenious_o confess_v that_o when_o his_o patient_n be_v under_o the_o aforesaid_a circumstance_n it_o never_o do_v he_o any_o service_n at_o all_o i_o again_o ask_v he_o why_o he_o do_v not_o vary_v his_o method_n his_o reply_n be_v it_o be_v a_o most_o noble_a alkaly_n and_o alexipharmick_n and_o what_o be_v general_o use_v and_o therefore_o he_o do_v not_o think_v fit_a to_o vary_v from_o a_o establish_v method_n a_o few_o day_n after_o i_o be_v call_v into_o a_o gentlewoman_n exact_o under_o the_o same_o circumstance_n before_o relate_v she_o be_v delirious_a to_o the_o high_a degree_n have_v violent_a spasme_n and_o convulsion_n of_o the_o nerve_n and_o all_o other_o symptom_n of_o a_o malignant_a fever_n of_o her_o life_n i_o do_v not_o despair_n and_o by_o the_o plentiful_a use_n of_o proper_a acid_n all_o symptom_n soon_o vanish_v and_o in_o a_o week_n time_n she_o be_v fit_a to_o go_v abroad_o beside_o this_o i_o can_v instance_n a_o hundred_o case_n of_o the_o same_o nature_n but_o i_o design_v brevity_n i_o must_v own_v that_o other_o distemper_n may_v be_v complicate_v with_o the_o smallpox_n and_o other_o continue_a fever_n and_o acute_a distemper_n or_o from_o a_o different_a constitution_n of_o the_o air_n etc._n etc._n unusual_a symptom_n may_v appear_v in_o which_o case_n a_o general_a method_n must_v not_o be_v rely_v on_o but_o recourse_n must_v be_v also_o have_v to_o proper_a specific_v chap._n ii_o of_o the_o scurvy_a i_o be_o now_o come_v to_o treat_v upon_o the_o disuse_n of_o alkaly_n in_o the_o scurvy_a that_o reign_v distemper_n which_o few_o people_n be_v altogether_o free_a from_o and_o be_v by_o most_o man_n account_v incurable_a or_o at_o least_o it_o for_o the_o most_o part_n prove_v so_o but_o here_o i_o expect_v the_o cry_n of_o all_o mankind_n against_o i_o what!_o say_v there_o be_v no_o acidity_n in_o the_o blood_n in_o the_o scurvy_a what!_o be_v it_o but_o a_o acidity_n in_o the_o blood_n that_o be_v the_o occasion_n of_o the_o break_n out_o of_o scab_n pimple_n blotche_n etc._n etc._n upon_o the_o skin_n what!_o but_o a_o sharpness_n and_o acidity_n in_o the_o blood_n occasion_n those_o wander_a pain_n and_o a_o thousand_o other_o symptom_n that_o people_n labour_v
which_o by_o many_o experiment_n i_o have_v find_v to_o be_v as_o much_o a_o alkaly_n as_o either_o crab_n eye_n coral_n pearl_n etc._n etc._n the_o which_o i_o suppose_v no_o man_n will_v deny_v now_o it_o be_v grant_v that_o the_o matter_n contain_v in_o the_o aforesaid_a nodes_fw-la to_o be_v a_o alkaly_n how_o be_v it_o possible_a for_o this_o distemper_n to_o proceed_v from_o acid_n when_o in_o those_o very_a part_n where_o the_o distemper_n most_o violent_o rage_v there_o shall_v be_v produce_v such_o large_a quantity_n of_o a_o alkalious_a substance_n for_o if_o the_o distemper_n proceed_v from_o acid_n as_o it_o be_v general_o agree_v upon_o the_o patient_n need_v not_o clog_v his_o stomach_n with_o alkaly_n as_o be_v general_o practise_v there_o be_v a_o remedy_n already_o place_v in_o the_o part_n affect_v and_o i_o very_o believe_v that_o the_o only_a reason_n why_o this_o distemper_n have_v be_v account_v among_o the_o opprobria_fw-la medicorum_fw-la have_v be_v from_o the_o mistake_a notion_n they_o have_v have_v concern_v it_o but_o if_o man_n will_v still_o persist_v to_o assert_v that_o this_o distemper_n proceed_v from_o acid_n and_o at_o the_o same_o time_n own_o the_o chalky_a substance_n beforementioned_a which_o be_v only_o the_o morbific_a matter_n indurate_v to_o be_v a_o alkaly_n they_o must_v tacit_o believe_v the_o doctrine_n of_o transmutation_n though_o open_o they_o be_v ashamed_a to_o own_v it_o and_o will_v laugh_v at_o and_o ridicule_n those_o that_o do_v but_o this_o be_v not_o all_o for_o suppose_v the_o acid_n matter_n cause_v this_o distemper_n to_o be_v transmute_v into_o a_o chalky_a alkalious_a substance_n the_o distemper_n must_v never_o more_o pretend_v to_o come_v in_o or_o near_o the_o part_n where_o this_o substance_n be_v lodge_v it_o be_v place_v as_o a_o sentry_n to_o guard_v it_o off_o nay_o the_o blood_n at_o time_n must_v all_o or_o at_o least_o great_a part_n of_o it_o pass_v through_o the_o part_n or_o part_n where_o this_o chalky_a substance_n be_v lodge_v by_o which_o mean_v a_o man_n will_v think_v it_o shall_v be_v sufficient_o guard_v from_o any_o more_o grow_a acid_n and_o so_o by_o consequence_n when_o the_o chalky_a nodes_fw-la be_v once_o settle_v people_n have_v not_o the_o least_o reason_n for_o the_o future_a to_o be_v in_o fear_n of_o the_o return_n of_o their_o distemper_n the_o contrary_a of_o which_o a_o great_a many_o honest_a gentleman_n to_o their_o sorrow_n experience_n so_o that_o a_o man_n will_v think_v that_o these_o very_a nodes_fw-la alone_o be_v sufficient_a if_o there_o be_v no_o other_o reason_n to_o be_v give_v for_o it_o to_o satisfy_v any_o man_n who_o be_v master_n of_o his_o reason_n that_o acid_n be_v not_o and_o that_o alkaly_n be_v the_o cause_n of_o this_o distemper_n and_o if_o the_o blood_n abound_v with_o too_o great_a a_o quantity_n of_o alkalious_a particle_n the_o give_v of_o alkaly_n must_v be_v preposterous_a be_v be_v to_o add_v fuel_n to_o the_o flame_n which_o instead_o of_o quench_v or_o extinguish_n make_v it_o so_o much_o the_o great_a it_o may_v not_o be_v amiss_o to_o take_v notice_n that_o few_o people_n be_v trouble_v with_o the_o gout_n but_o those_o who_o drink_v large_a quantity_n of_o wine_n or_o some_o other_o generous_a liquor_n abound_v with_o vinous_a spirit_n so_o that_o the_o blood_n and_o other_o juice_n be_v impregnate_v with_o the_o say_v vinous_a spirit_n these_o spirit_n meet_v with_o the_o volatile_a alkalious_a salt_n of_o which_o even_o the_o blood_n of_o sound_a people_n be_v never_o destitute_a by_o the_o mean_n of_o which_o salt_n the_o vinous_a spirit_n be_v coagulate_v and_o turn_v into_o that_o substance_n or_o somewhat_o like_o it_o which_o helmont_n call_v his_o offa_n alba_n which_o coagulate_v substance_n not_o be_v capable_a of_o move_v with_o the_o blood_n and_o juice_n through_o the_o small_a vessel_n cause_n obstruction_n and_o violent_a pain_n and_o in_o time_n by_o the_o addition_n of_o other_o gross_a terrestrious_a particle_n into_o the_o beforementioned_a chalky_a substance_n by_o the_o foresay_a coagulation_n of_o vinous_a spirit_n with_o the_o volatile_a alkaly_n of_o the_o blood_n may_v a_o very_a good_a reason_n be_v give_v for_o the_o generation_n of_o the_o stone_n in_o the_o bladder_n and_o kidney_n and_o mr._n boyle_n tell_v we_o be_v what_o helmont_n have_v before_o do_v that_o have_v obtain_v some_o stone_n of_o a_o certain_a lythotomist_n he_o put_v they_o into_o a_o retort_n and_o expose_v they_o to_o a_o strong_a fire_n and_o find_v that_o the_o better_a half_o consist_v of_o volatile_a alkalious_a salt_n like_v unto_o that_o obtainable_a from_o humane_a blood_n and_o a_o considerable_a quantity_n of_o heavy_a oil_n so_o that_o it_o be_v plain_a that_o the_o generation_n of_o the_o stone_n be_v not_o from_o acid_n but_o alkaly_n from_o which_o may_v be_v infer_v that_o it_o be_v not_o from_o the_o acidity_n of_o rhenish_a wine_n that_o make_v the_o drink_n of_o it_o pernicious_a to_o gouty_a people_n but_o from_o its_o abound_v with_o spirituous_a particle_n more_o than_o most_o other_o wine_n chap._n iu._n of_o rheumatism_n this_o be_v another_o of_o the_o distemper_n general_o say_v to_o proceed_v from_o acid_n in_o the_o blood_n but_o very_o false_o as_o i_o hope_v full_o to_o make_v appear_v i_o have_v have_v to_o do_v with_o multitude_n under_o this_o distemper_n and_o that_o thanks_o to_o god_n with_o very_o good_a success_n i._o shall_v not_o trouble_v myself_o to_o investigate_v the_o original_a cause_n of_o this_o distemper_n which_o be_v various_a that_o be_v foreign_a to_o my_o design_n but_o shall_v immediate_o proceed_v to_o the_o business_n i_o have_v undertake_v first_o of_o all_o have_v by_o the_o fire_n analyze_v the_o blood_n of_o rheumatic_a person_n i_o have_v find_v it_o to_o abound_v more_o with_o alkanious_a particle_n than_o that_o of_o sound_a person_n but_o not_o the_o least_o grain_n of_o any_o acid_n substance_n in_o it_o from_o which_o alone_a it_o may_v ready_o enough_o be_v infer_v that_o it_o proceed_v not_o from_o acid_n but_o on_o the_o contrary_a from_o alkaly_n but_o it_o may_v be_v object_v from_o whence_o proceed_v that_o syziness_n and_o viscosity_n of_o the_o serum_fw-la which_o be_v general_o observe_v in_o the_o blood_n of_o rheumatic_a person_n if_o not_o from_o acid_n for_o we_o know_v that_o milk_n which_o be_v a_o sort_n of_o serum_fw-la of_o the_o blood_n let_v it_o be_v in_o never_o so_o fluid_a a_o state_n by_o the_o addition_n of_o any_o acid_n though_o never_o so_o gentle_a a_o great_a part_n of_o it_o will_v be_v immediate_o congulate_v and_o turn_v into_o curd_n to_o which_o i_o answer_v that_o the_o foresay_a objection_n be_v altogether_o invalid_a the_o viscousness_n that_o be_v observe_v in_o the_o serum_fw-la of_o the_o blood_n be_v quite_o different_a from_o that_o of_o the_o curd_n in_o milk_n though_o there_o be_v those_o substance_n contain_v in_o milk_n that_o be_v fit_a to_o make_v both_o blood_n and_o serum_fw-la but_o milk_n be_v a_o much_o more_o compound_a liquor_n than_o the_o serum_fw-la of_o the_o blood_n so_o the_o comparison_n be_v make_v between_o subject_n so_o vast_o different_a it_o be_v of_o no_o validity_n at_o all_o but_o suppose_v the_o comparison_n between_o the_o two_o liquor_n good_a what_o agreement_n be_v there_o between_o curd_n and_o a_o substance_n like_a unto_o jelly_n none_o at_o all_o that_o i_o know_v of_o but_o if_o instead_o of_o curdle_a milk_n they_o have_v make_v the_o comparison_n between_o the_o inviscate_v serum_fw-la and_o hartshorn_n jelly_n they_o have_v be_v in_o the_o right_n on_o it_o for_o indeed_o i_o know_v not_o any_o two_o subject_n more_o fit_a to_o be_v compare_v together_o but_o then_o this_o comparison_n will_v not_o in_o the_o least_o prove_v the_o inviscation_n of_o the_o serum_fw-la to_o proceed_v from_o acid_n but_o on_o the_o contrary_a from_o alkalious_a particle_n for_o every_o body_n that_o know_v what_o hartshorn_n be_v know_v that_o the_o reason_n of_o its_o make_v a_o jelly_n be_v from_o its_o abound_v with_o volatile_a alkalious_a salt_n and_o for_o the_o same_o reason_n it_o be_v that_o calf_n foot_n izing-glass_n ivory_n etc._n etc._n make_v jelly_n by_o what_o i_o have_v say_v i_o hope_v i_o have_v free_v acid_n from_o occasion_v the_o viscousness_n of_o the_o serum_fw-la of_o the_o blood_n in_o rheumatism_n which_o viscosity_n if_o it_o can_v be_v once_o take_v off_o every_o one_o know_v that_o the_o distemper_n immediate_o vanish_v but_o this_o be_v not_o to_o be_v do_v by_o alkaly_n that_o ever_o i_o can_v see_v although_o i_o have_v give_v they_o in_o large_a quantity_n but_o it_o be_v expeditious_o to_o be_v do_v by_o proper_a acid_n such_o as_o the_o beforementioned_a tincture_n of_o antimony_n etc._n etc._n and_o calibiat_n but_o
here_o i_o expect_v that_o people_n will_v think_v that_o i_o have_v catch_v myself_o in_o a_o trap_n when_o i_o bring_v in_o calibiat_n among_o the_o number_n of_o acid_n when_o they_o be_v general_o own_v by_o all_o mankind_n to_o be_v alkaly_n to_o confirm_v the_o truth_n of_o which_o they_o tell_v you_o it_o be_v plain_o manifest_a that_o file_n of_o iron_n will_v make_v as_o great_a a_o effervescency_n with_o all_o sort_n of_o acid_n as_o any_o of_o the_o alkaly_n i_o have_v mention_v therefore_o it_o be_v plain_a i_o must_v be_v much_o in_o the_o wrong_n in_o reckon_a calibiat_n among_o the_o number_n of_o acid_n from_o this_o difficulty_n i_o shall_v endeavour_v to_o extricate_v myself_o and_o likewise_o to_o prove_v that_o iron_n or_o steel_n until_o it_o be_v convert_v into_o a_o vitriol_n and_o every_o body_n will_v allow_v vitriol_n to_o be_v a_o acid_n can_v act_v upon_o the_o blood_n or_o serum_fw-la to_o cause_n any_o alteration_n in_o it_o nor_o so_o much_o as_o any_o way_n enter_v into_o the_o vein_n or_o artery_n it_o be_v the_o custom_n of_o skilful_a practitioner_n before_o they_o give_v steel_n medicine_n to_o inquire_v of_o their_o patient_n whether_o they_o be_v sensible_a of_o any_o acidity_n in_o their_o stomach_n in_o which_o part_n i_o do_v allow_v acid_n oftentimes_o to_o abound_v and_o that_o exorbitant_o if_o they_o be_v sensible_a of_o any_o acidity_n there_o it_o be_v then_o find_v necessary_a to_o give_v iron_n or_o steel_n without_o any_o preparation_n at_o all_o by_o reason_n that_o by_o the_o mean_n of_o the_o acid_n in_o the_o stomach_n it_o be_v turn_v into_o a_o vitriol_n and_o so_o make_v capable_a of_o be_v carry_v into_o the_o blood_n whereas_o in_o such_o case_n if_o it_o have_v be_v before_o satiate_v by_o a_o precedent_a preparation_n it_o have_v little_a or_o no_o effect_n at_o all_o on_o the_o other_o hand_n if_o there_o be_v no_o sensible_a acidity_n in_o the_o stomach_n iron_n or_o steel_n be_v give_v unprepared_a be_v carry_v off_o by_o stool_n without_o the_o least_o alteration_n or_o any_o part_n of_o it_o be_v admit_v into_o the_o blood_n all_o or_o most_o of_o the_o preparation_n of_o steel_n that_o i_o know_v of_o that_o be_v good_a for_o any_o thing_n be_v perform_v by_o the_o mean_n of_o acid_n which_o tend_v to_o the_o divide_v of_o their_o part_n and_o turn_v they_o into_o a_o vitriol_n now_o according_a to_o the_o difference_n of_o the_o acid_v use_v the_o result_n be_v a_o different_a sort_n of_o vitriol_n which_o have_v different_a operation_n but_o on_o the_o contrary_a alkaly_n do_v so_o lock_v up_o the_o body_n of_o iron_n as_o to_o make_v it_o unfit_a to_o be_v take_v as_o medicine_n by_o reason_n of_o its_o extraordinary_a hardness_n and_o firmness_n of_o texture_n the_o preparation_n of_o steel_n i_o general_o use_v be_v that_o which_o go_v by_o the_o name_n of_o dr._n willis_n preparation_n of_o steel_n and_o be_v now_o almost_o every_o where_o to_o be_v have_v which_o although_o it_o be_v grow_v common_a be_v for_o all_o that_o no_o despicable_a medicine_n and_o that_o which_o follow_v take_v of_o file_n of_o steel_n or_o rather_o iron_n very_o clean_a and_o free_a from_o dust_n one_o pound_n and_o half_a shall_v ammoniac_a two_o pound_n make_v the_o sal_fw-la ammoniac_a into_o very_o fine_a powder_n then_o mix_v they_o well_o together_o in_o a_o iron_n or_o stone_n mortar_n than_o put_v the_o mixture_n into_o a_o moist_a cellar_n and_o let_v it_o stand_v a_o week_n then_o put_v it_o into_o a_o very_a large_a crucible_n which_o cover_v with_o 〈◊〉_d piece_n of_o tile_n afterward_o put_v the_o crucible_n into_o a_o charcoal_n fire_n which_o increase_n by_o degree_n till_o the_o crucible_n be_v almost_o red_a hot_a after_o it_o have_v continue_v in_o this_o state_n about_o a_o hour_n take_v away_o the_o fire_n and_o let_v your_o calcine_v matter_n cool_v by_o degree_n when_o cold_a take_v it_o out_o of_o the_o crucible_n and_o make_v into_o fine_a powder_n in_o a_o glass_n or_o stone_n mortar_n than_o put_v it_o into_o a_o bottle_n with_o a_o wide_a mouth_n which_o stop_v with_o a_o glass_n stopple_n and_o keep_v in_o a_o warm_a place_n these_o two_o preparation_n proper_o give_v and_o with_o convenient_a vehicles_n i_o have_v know_v of_o very_o great_a use_n in_o rheumatism_n and_o the_o last_o when_o all_o other_o medicine_n have_v prove_v ineffectual_a have_v never_o once_o fail_v i_o in_o the_o most_o inveterate_a obstruction_n of_o the_o menses_fw-la in_o woman_n beside_o the_o forementioned_a preparation_n of_o steel_n i_o have_v frequent_o find_v cinnaber_n of_o antimony_n or_o even_o common_a cinnaber_n mix_v with_o a_o due_a proportion_n of_o gum_n guaiaci_n and_o give_v in_o large_a quantity_n to_o be_v of_o great_a use_n not_o only_o in_o confirm_a rheumatism_n but_o even_o in_o sciatica_n of_o long_a stand_n by_o the_o mean_n of_o which_o alone_o i_o have_v know_v many_o cure_v i_o do_v former_o believe_v cinnaber_n of_o antimony_n and_o common_a cinnaber_n to_o be_v alkaly_n but_o since_o i_o have_v more_o nice_o inquire_v into_o it_o i_o find_v that_o by_o a_o peculiar_a management_n a_o large_a quantity_n of_o a_o acid_a sulphurous_a spirit_n may_v be_v obtain_v from_o it_o before_o i_o conclude_v upon_o this_o head_n it_o will_v not_o i_o suppose_v be_v amiss_o to_o observe_v one_o thing_n more_o about_o the_o preparation_n of_o steel_n beforementioned_a and_o that_o be_v that_o whilst_o it_o be_v keep_v dry_a and_o in_o a_o powder_n it_o be_v one_o of_o the_o great_a deoppilative_n or_o opener_n of_o obstruction_n imaginable_a but_o let_v it_o be_v put_v into_o a_o cellar_n and_o run_v per_fw-la deliquium_fw-la which_o it_o will_v do_v in_o a_o few_o day_n fifty_o or_o sixty_o drop_n of_o the_o say_a oil_n per_fw-la deliquium_fw-la give_v twice_o a_o day_n in_o a_o strong_a decoction_n of_o oak_n bark_n i_o have_v of_o late_o find_v never_o to_o fail_v i_o in_o stop_v a_o seminal_a flux_n which_o all_o people_n will_v allow_v have_v hitherto_o be_v find_v as_o difficult_a a_o thing_n to_o do_v as_o any_o whatsoever_o some_o people_n have_v tell_v i_o that_o they_o suppose_v the_o stipticity_n to_o proceed_v from_o the_o decoction_n of_o oak_n bark_n only_o i_o have_v purposely_o try_v it_o alone_o and_o although_o i_o own_o oak_n bark_n to_o be_v a_o noble_a stiptic_n and_o to_o do_v wonder_n the_o decoction_n be_v take_v in_o at_o the_o mouth_n and_o by_o way_n of_o clyster_n in_o common_a simple_a diarrhea_n and_o even_o sometime_o in_o bloody_a flux_n yet_o in_o the_o case_n beforementioned_a it_o will_v do_v nothing_o at_o all_o but_o add_v some_o drop_n of_o the_o oil_n of_o mars_n to_o the_o decoction_n it_o have_v soon_o the_o desire_a effect_n chap._n v._n of_o consumption_n i_o have_v little_a to_o say_v upon_o this_o subject_a but_o that_o i_o have_v see_v great_a number_n of_o people_n under_o this_o circumstance_n to_o who_o have_v be_v give_v large_a quantity_n of_o alkaly_n and_o all_o sort_n of_o balsamic_n and_o those_o thing_n call_v pectoral_n without_o the_o least_o advantage_n in_o the_o world_n though_o i_o have_v see_v other_o who_o have_v have_v the_o manifest_a sign_n of_o a_o confirm_a phtisis_n or_o consumption_n who_o by_o the_o plentiful_a use_n of_o proper_a acid_n have_v be_v reduce_v from_o a_o state_n of_o die_v to_o that_o of_o perfect_a health_n my_o reason_n in_o short_a according_a to_o my_o best_a observation_n for_o the_o use_n of_o acid_n and_o the_o disuse_n of_o alkaly_n be_v as_o follow_v the_o globule_n of_o the_o blood_n by_o reason_n of_o so_o great_a a_o quantity_n of_o acrid_a alkalious_a lixivious_a particle_n be_v mix_v with_o it_o be_v break_v and_o confuse_o mix_v with_o the_o serum_fw-la be_v together_o with_o the_o serum_fw-la admit_v into_o the_o small_a glandule_n of_o the_o lung_n and_o not_o be_v capable_a of_o be_v discharge_v cause_n inflammation_n there_o and_o by_o consequence_n hectic_a fever_n which_o always_o precede_v and_o accompany_v a_o pthisis_n or_o consumption_n now_o by_o the_o use_n of_o alkaly_n and_o balsamick_n these_o extravasated_a globule_n be_v so_o far_o from_o be_v throw_v out_o and_o the_o deprave_a state_n of_o the_o blood_n from_o be_v alter_v that_o instead_o of_o it_o the_o state_n of_o the_o blood_n be_v make_v much_o worse_o by_o alkaly_n and_o by_o balsamick_n the_o pustle_v occasion_v from_o the_o extravasated_a globule_n be_v admit_v into_o the_o small_a glandule_n be_v bring_v to_o suppuration_n the_o necessary_a consequence_n of_o which_o be_v a_o ulceration_n and_o when_o so_o tender_a a_o part_n as_o the_o lung_n be_v be_v once_o ulcerate_v he_o must_v show_v himself_o a_o artist_n indeed_o that_o can_v heal_v such_o ulcer_n now_o proper_a acid_n be_v give_v
own_o that_o it_o may_v be_v rational_o enough_o object_v that_o my_o doctrine_n of_o acid_n do_v mighty_o thwart_v with_o that_o of_o specific_v since_o there_o be_v many_o specific_v that_o be_v neither_o alkaly_n nor_o acid_n yet_o seldom_o fail_v of_o cure_v distemper_n as_o rational_o to_o be_v suppose_v to_o proceed_v from_o alkalious_a particle_n abound_v as_o any_o whatsoever_o to_o which_o i_o answer_v that_o i_o have_v only_o bring_v my_o doctrine_n of_o acid_n upon_o the_o stage_n as_o a_o general_a one_o in_o opposition_n to_o the_o general_a and_o pernicious_a doctrine_n of_o alkaly_n for_o shall_v i_o deny_v the_o doctrine_n of_o specific_v i_o must_v deny_v matter_n of_o fact_n which_o be_v what_o i_o shall_v never_o do_v till_o i_o be_o total_o deprive_v of_o my_o reason_n there_o be_v a_o little_a herb_n call_v paronichia_n cum_fw-la foliis_fw-la rutaceis_n or_o whitlow_n grass_n with_o leaf_n like_o rew_n the_o which_o the_o honourable_a mr._n boyle_n recommend_v as_o a_o specific_a in_o the_o king_n be_v evil_a which_o herb_n i_o have_v immerge_v both_o in_o moderate_o acid_n and_o alkalious_a liquor_n yet_o can_v not_o perceive_v any_o luctus_n or_o effervescency_n yet_o i_o have_v know_v it_o do_v wonder_n in_o the_o forementioned_a distemper_n and_o that_o without_o have_v the_o least_o sensible_a operation_n i_o shall_v instance_n in_o one_o particular_a a_o poor_a woman_n in_o worcester_n have_v one_o only_a child_n of_o about_o ten_o year_n of_o age_n who_o by_o weave_v of_o bonelace_n maintain_v both_o her_o mother_n and_o herself_o the_o mother_n of_o the_o child_n come_v one_o day_n to_o i_o make_v a_o great_a complaint_n that_o she_o be_v undo_v i_o ask_v she_o the_o cause_n of_o her_o complaint_n she_o tell_v i_o her_o child_n who_o keep_v she_o in_o her_o old_a age_n from_o beg_v have_v for_o two_o year_n have_v scrofulous_a tumour_n in_o and_o about_o her_o privity_n and_o that_o about_o three_o month_n before_o one_o of_o the_o say_a tumour_n begin_v to_o ulcerate_v and_o that_o now_o the_o ulcer_n be_v creep_v into_o her_o body_n which_o make_v her_o uneapable_a of_o sit_v i_o go_v immediate_o with_o the_o poor_a woman_n to_o see_v her_o daughter_n and_o find_v what_o she_o say_v be_v true_a the_o poor_a girl_n be_v the_o most_o miserable_a spectacle_n i_o ever_o see_v i_o remember_v what_o mr._n boyle_n have_v say_v concern_v paronychia_fw-la and_o be_v sufficient_o satisfy_v that_o there_o be_v not_o the_o least_o reason_n of_o doubt_v the_o truth_n of_o any_o thing_n he_o have_v say_v when_o he_o relate_v it_o as_o matter_n of_o fact_n upon_o his_o own_o knowledge_n i_o be_v resolve_v to_o try_v it_o upon_o this_o girl_n i_o first_o of_o all_o purge_a she_o three_o or_o four_o time_n with_o calamelanos_fw-la rezin_n of_o jallap_v and_o cremor_n tartar_n i_o afterward_o give_v she_o two_o large_a handful_n of_o the_o say_a herb_n dry_v order_v she_o to_o put_v it_o into_o two_o gallon_n of_o small_a beer_n after_o it_o have_v do_v work_v and_o let_v it_o stand_v six_o day_n and_o then_o to_o drink_v it_o for_o her_o constant_a drink_n she_o continue_v to_o take_v it_o for_o about_o two_o month_n in_o which_o time_n without_o apply_v any_o thing_n to_o the_o ulcer_n save_v clean_a clothes_n both_o ulcer_n and_o tumour_n vanish_v and_o she_o continue_v well_o till_o i_o leave_v worcester_n which_o be_v two_o year_n after_o the_o cure_n be_v perform_v and_o be_v so_o still_o for_o aught_o i_o can_v hear_v i_o have_v several_a time_n inquire_v after_o she_o another_o instance_n of_o the_o operation_n of_o specific_v without_o their_o be_v either_o alkaly_n or_o acid_n be_v that_o frequent_o experiment_a decoction_n of_o mercury_n after_o have_v be_v boil_v for_o a_o considerable_a time_n in_o water_n have_v be_v find_v not_o to_o have_v lose_v the_o least_o grain_n of_o its_o former_a weight_n or_o impart_v either_o taste_n or_o colour_n to_o the_o water_n yet_o this_o water_n in_o which_o the_o mercury_n have_v be_v decoct_v have_v not_o fail_v of_o kill_v and_o bring_v away_o worm_n when_o other_o celebrate_a medicine_n have_v fail_v likewise_o crocus_n mettalorum_fw-la and_o some_o other_o preparation_n of_o antimony_n be_v bare_o infuse_v in_o wine_n without_o lose_v the_o least_o grain_n of_o their_o weight_n or_o impart_v either_o smell_n taste_v or_o colour_n to_o the_o wine_n in_o which_o they_o be_v infuse_v yet_o never_o fail_v of_o give_v the_o wine_n a_o violent_o emettick_n quality_n i_o myself_o have_v at_o several_a time_n pour_v above_o twenty_o quart_n of_o canary_n upon_o one_o and_o the_o same_o ounce_n of_o crocus_n mettalorum_fw-la powder_a and_o find_v that_o the_o last_o quart_n be_v as_o violent_o emettick_n as_o the_o first_o although_o after_o nice_a trial_n i_o can_v not_o find_v that_o the_o powder_n be_v diminish_v one_o grain_n in_o its_o weight_n or_o have_v as_o be_v before-observed_n cause_v the_o least_o sensible_a alteration_n in_o the_o wine_n the_o cortex_fw-la that_o noble_a specific_a in_o all_o intermit_a fever_n i_o do_v apprehend_v to_o perform_v its_o office_n as_o it_o be_v either_o a_o alkaly_a or_o acid_n though_o be_v mix_v with_o acid_n it_o perform_v its_o work_n much_o better_a than_o without_o they_o it_o be_v a_o general_a complaint_n against_o that_o noble_a medicine_n and_o be_v the_o only_a occasion_n of_o deter_v some_o people_n from_o the_o use_n of_o it_o that_o be_v give_v in_o never_o so_o large_a quantity_n especial_o in_o quartan_o it_o only_o put_v off_o the_o fit_a for_o a_o time_n but_o do_v not_o total_o eradicate_v the_o distemper_n it_o return_v after_o a_o certain_a period_n to_o obviate_v which_o inconvenience_n i_o have_v be_v advise_v to_o give_v it_o after_o the_o follow_a manner_n which_o seldom_o or_o never_o fail_v of_o prevent_v the_o return_n of_o the_o distemper_n two_o hour_n before_o the_o fit_a i_o give_v a_o gentle_a emettick_n after_o that_o have_v do_v work_v a_o 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quart_n boyl_n to_o the_o consumption_n of_o one_o half_n when_o cold_a strain_n out_o and_o keep_v for_o use_v by_o this_o method_n i_o have_v know_v three_o or_o four_o ounce_n of_o the_o cortex_fw-la perfect_o cure_v quartan_n without_o any_o relapse_n after_o people_n have_v take_v a_o pound_n or_o more_o after_o the_o common_a method_n which_o have_v only_o put_v by_o the_o fit_v for_o a_o time_n the_o reason_n as_o i_o apprehend_v why_o this_o method_n of_o give_v the_o cortex_fw-la shall_v be_v more_o prevalent_a than_o that_o common_o take_v be_v the_o particle_n of_o the_o cortex_fw-la be_v very_o firm_a the_o medicine_n be_v take_v and_o the_o patient_n fast_v three_o or_o four_o hour_n after_o it_o it_o slide_v out_o of_o the_o stomach_n into_o the_o small_a gut_n and_o so_o on_o the_o small_a gut_n be_v empty_a there_o be_v not_o pressure_n enough_o to_o squeeze_v but_o a_o very_a small_a quantity_n of_o it_o into_o the_o lacteal_v vessel_n so_o that_o the_o great_a 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