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embryon_n seem_v to_o
teach_v we_o that_o some_o influence_n whatever_o it_o be_v derive_v from_o the_o brain_n to_o the_o heart_n be_v absolute_o necessary_a to_o the_o incitement_n and_o perpetuation_n of_o the_o motion_n of_o the_o heart_n for_o the_o brain_n be_v in_o a_o great_a part_n perfect_v before_o the_o heart_n though_o those_o two_o member_n ob_fw-la communem_fw-la officii_fw-la necessitudinem_fw-la be_v almost_o congenite_fw-la and_o i_o have_v good_a cause_n to_o believe_v that_o the_o exordium_n of_o the_o brain_n be_v that_o colliquamentum_fw-la which_o be_v first_o see_v in_o a_o egg_n after_o the_o first_o day_n incubation_n of_o the_o hen_n and_o which_o by_o the_o same_o warmth_n continue_v do_v in_o a_o short_a time_n concrete_a and_o be_v condense_v into_o a_o thick_a substance_n that_o be_v soon_o invest_v as_o every_o viscid_a humour_n be_v wont_a to_o be_v with_o a_o thin_a film_n or_o membrane_n and_o shoot_v forth_o from_o itself_o little_a nerve_n as_o branch_n every_o way_n from_o the_o observation_n of_o which_o that_o incomparable_a man_n sir_n george_n ent_n doubt_v not_o public_o to_o declare_v himself_o to_o be_v of_o this_o opinion_n 7._o that_o not_o the_o heart_n but_o the_o brain_n be_v the_o fountain_n of_o life_n his_o word_n be_v these_o cor_fw-la enim_fw-la uti_fw-la arbitror_fw-la non_fw-la est_fw-la fons_fw-la aquavitae_fw-la qui_fw-la cerebro_fw-la peculiaris_fw-la est_fw-la sed_fw-la rivulus_fw-la duntaâ—at_fw-la accessorius_fw-la which_o yet_o be_v no_o new_a opinion_n but_o ascribe_v by_o galen_n to_o erasistratus_n 3._o who_o say_v omnium_n quae_fw-la in_o corpore_fw-la sunt_fw-la principium_fw-la esse_fw-la cerebrum_fw-la apparet_fw-la and_o assert_v by_o hippon_n who_o censorinus_n introduce_v right_o teach_v caput_fw-la primò_fw-la fieri_fw-la now_o what_o can_v we_o with_o equal_a probability_n conceive_v to_o be_v the_o reason_n why_o nature_n finish_v the_o brain_n before_o the_o heart_n as_o this_o i_o have_v here_o give_v viz._n because_o the_o heart_n even_o from_o the_o beginning_n have_v need_n of_o some_o influence_n to_o be_v transmit_v from_o the_o brain_n to_o it_o for_o the_o incitement_n and_o continuation_n of_o its_o motion_n as_o well_o as_o for_o the_o nutrition_n of_o its_o substance_n the_o latter_a of_o which_o benefit_n be_v common_a to_o the_o heart_n with_o all_o other_o part_n of_o the_o body_n second_o it_o be_v high_o probable_a that_o the_o brain_n be_v not_o only_o the_o laboratory_n but_o also_o the_o common_a promptuary_n of_o the_o true_a succus_fw-la nutritius_fw-la and_o that_o the_o nerve_n be_v the_o cane_n or_o filtre_n through_o who_o long_a and_o narrow_a pore_n the_o same_o roscid_a nutritive_a liquor_n be_v gentle_o distribute_v to_o all_o part_n for_o their_o nourishment_n both_o which_o proposition_n have_v be_v former_o with_o many_o considerable_a argument_n draw_v as_o well_o from_o experiment_n anatomical_a as_o from_o reason_n assert_v by_o sir_n george_n ent_n dr._n glisson_n and_o if_o it_o be_v lawful_a for_o i_o to_o put_v myself_o into_o the_o same_o period_n with_o such_o excellent_a man_n myself_o this_o therefore_o be_v suppose_v it_o be_v not_o unreasonable_a to_o think_v that_o this_o roscid_n balsamic_a and_o spirituose_fw-la liquor_n by_o many_o call_v succus_fw-la nervosus_fw-la be_v for_o the_o most_o part_n in_o sufficient_a plenty_n in_o the_o brain_n do_v at_o all_o time_n touch_v and_o soak_v into_o the_o open_a pore_n of_o all_o the_o nerve_n thence_o elonge_v but_o more_o copious_o into_o the_o nerve_n that_o extend_v themselves_o into_o the_o fibrose_a substance_n of_o the_o heart_n because_o the_o heart_n be_v furnish_v with_o many_o more_o and_o large_a nerve_n than_o any_o other_o muscle_n of_o the_o whole_a body_n and_o because_o the_o extreme_o narrow_a cavity_n of_o the_o nerve_n be_v full_a of_o a_o spungy_a medullary_n substance_n and_o continual_o wet_a with_o the_o same_o roscid_a liquor_n creep_v through_o they_o therefore_o the_o liquor_n can_v flow_v out_o of_o the_o low_a end_n of_o they_o into_o the_o fibre_n of_o the_o heart_n otherwise_o than_o guttatim_fw-la drop_v after_o drop_n as_o all_o liquor_n chief_o such_o as_o have_v any_o thing_n of_o viscidity_n slow_o creep_v along_o the_o thread_n of_o filtre_n and_o when_o they_o at_o length_n arrive_v at_o the_o end_n fall_v down_o in_o equal_a drop_n with_o equal_a pause_n betwixt_o the_o precedent_n and_o the_o succeed_v drop_n far_o because_o the_o distillation_n of_o each_o drop_n be_v almost_o momentaneous_a not_o persevere_v thence_o it_o seem_v to_o come_v that_o the_o constriction_n of_o the_o heart_n be_v perform_v and_o finish_v in_o a_o moment_n and_o a_o pause_n succeed_v in_o the_o next_o moment_n till_o a_o second_o drop_n come_v to_o cause_v a_o second_o constriction_n and_o so_o forward_o and_o since_o in_o the_o brain_n or_o fountain_n of_o this_o roscid_a liquor_n there_o be_v always_o plenty_n to_o maintain_v a_o perpetual_a succession_n of_o drop_n and_o the_o liquor_n itself_o be_v in_o the_o state_n of_o health_n always_o of_o the_o same_o temper_n and_o consistence_n and_o the_o narrow_a canales_n in_o the_o nerve_n always_o equal_o retard_v its_o descent_n and_o efflux_n therefore_o it_o seem_v necessary_a that_o the_o time_n of_o quiet_a or_o the_o pause_v intervenient_a betwixt_o the_o drop_n shall_v be_v equal_a so_o long_o as_o the_o liquor_n retain_v the_o same_o degree_n of_o fluxility_n or_o be_v not_o hinder_v by_o great_a violence_n but_o if_o it_o happen_v that_o the_o liquor_n be_v become_v either_o more_o thin_a and_o fluxible_a than_o be_v fit_a as_o common_o it_o do_v upon_o debauch_n with_o wine_n or_o other_o strong_a drink_n or_o saline_n acrimonious_a acid_n or_o of_o any_o other_o vicious_a and_o irritate_v quality_n as_o often_o it_o be_v vitiate_a in_o many_o malady_n chief_o in_o scorbuto_n inveterato_fw-la or_o fall_v into_o a_o fermentation_n which_o i_o have_v reason_n to_o conjecture_v it_o always_o do_v in_o fever_n and_o more_o eminent_o in_o the_o small_a pox_n the_o matter_n of_o which_o seem_v to_o be_v not_o the_o blood_n but_o the_o succus_fw-la nutritius_fw-la in_o a_o peculiar_a manner_n corrupt_v and_o critical_o transmit_v from_o the_o brain_n through_o the_o nerve_n into_o the_o habit_n of_o the_o body_n or_o be_v agitate_a by_o any_o swift_a motion_n as_o in_o the_o more_o violent_a passion_n of_o the_o mind_n and_o chief_o in_o anger_n it_o be_v in_o all_o these_o case_n the_o motion_n and_o distil_v of_o it_o into_o the_o fibre_n of_o the_o heart_n must_v be_v accelerate_a proportionate_o and_o consequent_o the_o systole_n of_o the_o heart_n will_v be_v more_o frequent_o repete_v and_o the_o pause_v intercedent_a betwixt_o they_o will_v be_v as_o those_o intervenient_a betwixt_o the_o drop_n short_a and_o here_o a_o fair_a occasion_n offer_v itself_o to_o i_o of_o expatiate_v into_o the_o various_a and_o numerose_n difference_n of_o pulse_n of_o the_o heart_n and_o endeavour_v to_o solve_v they_o rational_o by_o this_o hypothesis_n which_o alone_o be_v capable_a to_o do_v it_o but_o the_o shortness_n of_o the_o time_n appoint_v for_o my_o sit_v in_o this_o place_n forbid_v i_o to_o make_v use_n of_o the_o occasion_n of_o this_o stillicidium_fw-la or_o guttulation_n of_o the_o succus_fw-la nervosus_fw-la out_o of_o the_o end_n of_o the_o cardiac_n nerve_n we_o have_v various_a familiar_a example_n we_o see_v that_o sponge_n filtre_n and_o even_o glass_n tube_v of_o very_o small_a bore_n though_o they_o be_v continual_o replete_a with_o water_n or_o any_o other_o liquor_n yet_o the_o liquor_n do_v not_o flow_v out_o of_o their_o low_a end_n or_o orifice_n in_o a_o continue_a course_n as_o water_n gush_v out_o of_o a_o fountain_n or_o out_o of_o the_o cock_n of_o a_o cistern_n but_o by_o drop_n with_o aequitemporaneous_a stop_n or_o pause_n betwixt_o the_o drop_n the_o true_a cause_n of_o which_o effect_n seem_v to_o be_v this_o the_o great_a narrowness_n of_o the_o canales_n which_o impede_v the_o free_a permeation_n of_o the_o liquor_n the_o little_a particle_n or_o moleculae_fw-la of_o the_o liquor_n be_v not_o exact_o smooth_a but_o villose_o and_o viscose_v and_o therefore_o they_o be_v force_v to_o creep_v along_o with_o a_o slow_a pace_n through_o the_o cavity_n of_o the_o tube_n who_o superfice_n within_o be_v equal_o full_a of_o little_a asperity_n too_o so_o that_o they_o must_v as_o they_o pass_v along_o be_v put_v into_o a_o vertiginose_a motion_n and_o interrupt_v their_o course_n and_o consequent_o fall_v out_o of_o the_o low_a end_n of_o the_o sponge_n filtre_n or_o tube_n guttatim_fw-la now_o since_o the_o nerve_n be_v like_o indian_a cane_n compose_v of_o filament_n run_v their_o whole_a length_n in_o direct_a line_n a_o medullary_n and_o spungy_a substance_n and_o many_o little_a interstice_n interjacent_a betwixt_o the_o filament_n with_o a_o thin_a coat_n invest_v they_o and_o since_o the_o superfice_n of_o their_o
see_v that_o the_o liquor_n find_v in_o the_o pericardium_n be_v easy_o capable_a of_o coagulation_n either_o by_o heat_n or_o cold_a so_o as_o to_o become_v like_o jelly_n of_o hartshorn_n or_o the_o white_a of_o a_o egg_n harden_v by_o boil_v as_o the_o serum_fw-la of_o the_o blood_n will_v do_v and_o observe_v the_o various_a little_a gland_n seat_v about_o the_o basis_n of_o the_o heart_n for_o which_o i_o can_v find_v no_o other_o equal_o probable_a use_n as_o to_o instil_v the_o serum_fw-la into_o the_o pericardium_n to_o facilitate_v the_o motion_n of_o the_o heart_n which_o most_o certain_o that_o liquor_n do_v as_o the_o humour_n instill_v out_o of_o the_o glandulae_fw-la lacrymale_n upon_o the_o outside_n of_o the_o eye_n serve_v to_o moisten_v and_o make_v they_o more_o easy_o movable_a every_o way_n when_o i_o have_v i_o say_v observe_v and_o consider_v these_o thing_n i_o reject_v that_o thought_n and_o embrace_v this_o of_o the_o absorption_n of_o the_o relic_n of_o the_o succus_fw-la nervosus_fw-la by_o the_o vein_n of_o the_o heart_n the_o second_o be_v that_o the_o diastole_n of_o the_o heart_n be_v cause_v partly_o by_o the_o relaxation_n of_o the_o fibre_n of_o it_o spontaneous_o restore_v themselves_o to_o their_o natural_a posture_n and_o length_n as_o all_o other_o tensile_n body_n be_v wont_a to_o do_v after_o they_o have_v be_v distend_v partly_o by_o the_o force_n of_o the_o blood_n rush_v out_o of_o the_o ear_n into_o the_o ventricles_n of_o the_o heart_n and_o replenish_n they_o wherefore_o the_o wisdom_n of_o nature_n be_v admirable_a also_o in_o this_o that_o she_o ordain_v these_o two_o cause_n of_o the_o diastole_n viz._n the_o relaxation_n of_o the_o fibre_n and_o the_o influx_n of_o the_o blood_n into_o the_o ventricles_n to_o be_v exact_o coincident_a that_o with_o unite_a force_n they_o may_v cooperate_v more_o efficacious_o whence_o it_o appear_v that_o in_o the_o diastole_n the_o heart_n be_v not_o whole_o passive_a as_o all_o anatomist_n hitherto_o have_v believe_v it_o to_o be_v for_o unless_o the_o fibres_n do_v restore_v themselves_o to_o their_o former_a longitude_n which_o be_v a_o natural_a action_n at_o the_o same_o time_n the_o influx_n of_o the_o blood_n happen_v certain_o there_o can_v be_v no_o room_n to_o receive_v the_o blood_n because_o the_o inside_n of_o the_o ventricles_n will_v continue_v to_o touch_v each_o the_o other_o and_o so_o there_o can_v be_v no_o diastole_n the_o three_o and_o last_o be_v that_o it_o appear_v from_o the_o whole_a series_n of_o this_o discourse_n that_o the_o pulsation_n or_o constriction_n of_o the_o heart_n have_v its_o force_n from_o that_o mechanic_n power_n which_o be_v call_v the_o wedge_n and_o that_o the_o blood_n be_v express_v out_o of_o the_o heart_n by_o virtue_n of_o another_o mechanic_n power_n which_o be_v name_v the_o praelum_fw-la or_o press_n and_o consequent_o that_o the_o heart_n itself_o be_v as_o all_o automata_n be_v move_v not_o by_o spirit_n nor_o by_o a_o pulsifick_a faculty_n nor_o by_o rarefaction_n of_o the_o blood_n nor_o ebullition_n or_o fermentation_n of_o the_o blood_n nor_o by_o explosion_n of_o saline_n and_o acid_n spirituose_fw-la liquor_n but_o by_o mechanic_n necessity_n which_o from_o the_o beginning_n i_o hope_v i_o shall_v be_v able_a fair_o to_o prove_v if_o the_o success_n of_o my_o endeavour_n have_v not_o be_v answerable_a to_o that_o hope_n i_o will_v not_o go_v about_o to_o extenuate_v the_o blame_n of_o my_o faileur_n by_o cite_v example_n of_o much_o great_a wit_n which_o have_v before_o i_o in_o vain_a attempt_v to_o reveal_v the_o same_o secret_a of_o nature_n but_o consolate_v myself_o with_o this_o that_o my_o judge_n be_v man_n no_o less_o belove_v for_o their_o exemplary_a candour_n and_o humanity_n than_o honour_v for_o their_o excellency_n in_o all_o kind_n of_o learning_n and_o who_o need_v not_o be_v put_v in_o mind_n that_o truth_n be_v a_o tree_n who_o root_n be_v in_o heaven_n and_o of_o which_o even_o the_o wise_a of_o we_o dim-sighted_a mortal_n here_o upon_o earth_n see_v nothing_o but_o the_o shadow_n of_o its_o branch_n i_o will_v therefore_o conclude_v this_o inelaborate_a disquisition_n with_o that_o memorable_a say_n of_o the_o prince_n of_o roman_a orator_n consolation_n de_n his_o statuat_fw-la unusquisque_fw-la ut_fw-la libet_fw-la quid_fw-la autem_fw-la verius_fw-la sit_fw-la deus_fw-la ipse_fw-la viderit_fw-la hominem_fw-la quidem_fw-la scire_fw-la arbitror_fw-la neminem_fw-la ¶_o ⸫_o my_o lecture_n such_o as_o they_o be_v much_o honour_a auditor_n you_o have_v with_o oblige_a patience_n hear_v be_v please_v i_o beseech_v you_o to_o hear_v also_o before_o you_o rise_v a_o word_n which_o i_o have_v to_o speak_v in_o my_o own_o defence_n be_v it_o not_o indecent_a to_o compare_v small_a thing_n with_o great_a i_o shall_v venture_v perhaps_o to_o advertise_v you_o that_o the_o reason_n which_o induce_v i_o to_o attempt_v a_o reformation_n of_o the_o borellian_a hypothesis_n of_o the_o motion_n of_o the_o heart_n which_o doctor_n harvey_n himself_o call_v the_o sun_n of_o the_o microcosm_n sanguine_a seem_v to_o have_v some_o kind_n of_o analogy_n to_o those_o which_o move_v the_o prince_n of_o astronomer_n tycho_n brahe_n to_o dislike_v the_o ptolemaic_a system_n of_o the_o macrocosm_n or_o great_a world_n and_o to_o excogitate_v a_o new_a one_o of_o more_o probability_n and_o neatness_n for_o as_o tycho_n animadvert_v that_o the_o celestial_a orb_n have_v be_v by_o ptolemy_n distribute_v unhansom_o that_o so_o many_o and_o so_o great_a epicycle_n be_v in_o vain_a imagine_v to_o explicate_v the_o retrogradation_n of_o the_o planet_n and_o their_o various_a respect_n to_o the_o sun_n and_o that_o the_o equality_n of_o the_o circular_a motion_n be_v measure_v not_o from_o the_o centre_n of_o its_o proper_a circle_n as_o it_o ought_v but_o from_o the_o centre_n of_o another_o eccentric_a circle_n against_o the_o first_o principle_n of_o nature_n and_o art_n invent_v a_o new_a system_fw-la exempt_a from_o all_o these_o incommodity_n which_o be_v in_o truth_n the_o copernican_n invert_v so_o i_o conceive_v that_o in_o the_o borellian_a hypothesis_n and_o explosion_n of_o i_o know_v not_o what_o saline_n and_o acid_n material_n in_o the_o heart_n be_v not_o only_o in_o itself_o extreme_o improbable_a and_o incongruous_a to_o the_o wisdom_n of_o nature_n which_o always_o constitute_v certain_a and_o regular_a cause_n to_o produce_v certain_a and_o regular_a effect_n but_o also_o unnecessary_o suppose_v to_o solve_v the_o phaenomenon_n of_o the_o heart_n pulsation_n set_v my_o dull_a brain_n on_o work_n to_o reform_v it_o and_o soon_o invent_v another_o that_o seem_v both_o free_a from_o those_o inconvenience_n and_o more_o agreeable_a to_o the_o organical_a structure_n of_o the_o heart_n to_o which_o above_o all_o thing_n it_o be_v requisite_a i_o shall_v endeavour_v to_o adjust_a it_o this_o i_o think_v myself_o oblige_v to_o signify_v lest_o any_o here_o shall_v believe_v either_o that_o i_o have_v usurp_v to_o myself_o this_o whole_a system_n of_o the_o motion_n of_o the_o heart_n from_o that_o most_o excellent_a mathematician_n alphonsus_n borellus_n who_o memory_n i_o high_o honour_n or_o that_o i_o lay_v claim_n to_o more_o than_o a_o candid_a attempt_n to_o reform_v it_o ¶_o ⸫_o epilogus_fw-la praelectionum_fw-la quidem_fw-la vela_fw-la jam_fw-la tandem_fw-la contraxi_fw-la nondum_fw-la tamen_fw-la dissolutam_fw-la video_fw-la concionem_fw-la resistamus_fw-la igitur_fw-la hîc_fw-la parumper_fw-la auditores_fw-la ornatissimâ—_n si_fw-la vobis_fw-la ita_fw-la videatur_fw-la &_o ad_fw-la stupendam_fw-la illam_fw-la cujus_fw-la rationem_fw-la mechanicam_fw-la hactenus_fw-la tam_fw-la anxiè_fw-la inquisivimus_fw-la cordis_n fabricam_fw-la seriò_fw-la respiciamus_fw-la ind_n enim_fw-la etiamsi_fw-la alia_fw-la omne_fw-la in_o universitate_fw-la rerum_fw-la deessent_fw-la divinae_fw-la architecturae_fw-la documenta_fw-la cuivis_fw-la hominum_fw-la pronum_fw-la est_fw-la infer_v &_o quam_fw-la sit_fw-la immensa_fw-la illius_fw-la caeterorumque_fw-la omnium_fw-la in_o hoc_fw-la mundo_fw-la adspect_n abilium_fw-la conditoris_fw-la solertia_fw-la quámque_fw-la parum_fw-la ab_fw-la immedicabili_fw-la cum_fw-la animi_fw-la tum_fw-la mentis_fw-la stupiditate_fw-la olim_fw-la abfuerit_fw-la epicurus_n qui_fw-la animalia_fw-la casu_fw-la quodam_fw-la in_fw-la prima_fw-la rerum_fw-la procreatione_fw-la genita_fw-la fuisse_fw-la vecorditer_fw-la censuit_fw-la &_o opinatus_fw-la est_fw-la consequenter_fw-la totam_fw-la in_o iis_fw-la membrorum_fw-la varietatem_fw-la dearticulationemque_fw-la non_fw-la aliunde_fw-la quam_fw-la ex_fw-la atomorum_fw-la fortè_fw-la fortuna_fw-la post_fw-la infinitos_fw-la inter_fw-la se_fw-la in_o spatio_fw-la infinito_fw-la vortices_fw-la ita_fw-la concurrentium_fw-la atque_fw-la commistarum_fw-la dispositione_n extitisse_fw-la quamobrem_fw-la neque_fw-la ullam_fw-la fuisse_fw-la intelligentis_fw-la naturae_fw-la prudentiam_fw-la quae_fw-la ossa_fw-la cerebrum_fw-la cor_fw-la nervos_fw-la venas_fw-la quae_fw-la oculos_fw-la manus_fw-la pedes_fw-la viscera_fw-la quae_fw-la cetera_fw-la omne_fw-la conformans_fw-la ad_fw-la fine_n certos_fw-la seu_fw-la functiones_fw-la partibus_fw-la congruas_fw-la respexerit_fw-la sed_fw-la singulas_fw-la part_n ita_fw