best_a part_n of_o opium_n which_o be_v so_o much_o the_o better_a the_o more_o it_o abound_v with_o they_o 9_o if_o it_o yield_v any_o other_o tincture_n than_o red_a it_o be_v not_o right_a and_o the_o dull_a or_o pale_a the_o red_a be_v the_o worse_a or_o weak_a it_o be_v 10._o the_o best_a be_v heavy_a in_o proportion_n to_o its_o bulk_n which_o you_o may_v soon_o experiment_n thus_o weigh_v a_o ounce_n of_o each_o in_o the_o air_n then_o weigh_v they_o just_a as_o they_o be_v in_o the_o brass_n scales_n in_o water_n and_o the_o heavy_a will_n outweigh_v the_o other_o in_o water_n for_o the_o heavy_a any_o thing_n be_v the_o less_o water_n take_v from_o its_o weight_n in_o proportion_n to_o its_o bulk_n this_o be_v a_o infallible_a and_o most_o ready_a way_n to_o know_v the_o weight_n of_o any_o thing_n in_o proportion_n to_o its_o bulk_n note_v that_o my_o discourse_n be_v most_o particular_o concern_v the_o best_a sort_n of_o crude_a turkey_n opium_n that_o be_v the_o best_a that_o we_o have_v in_o common_a use_n and_o that_o its_o effect_n and_o not_o those_o of_o any_o preparation_n thereof_o be_v set_v down_o in_o the_o follow_a chapter_n chap_n iii_o the_o effect_n of_o opium_n use_v external_o opium_n use_v external_o have_v two_o sort_n of_o effect_n upon_o a_o humane_a body_n 1._o as_o a_o opiate_n to_o cause_n sleep_n take_v away_o pain_n etc._n etc._n 2._o as_o a_o alterative_a of_o the_o part_n it_o be_v apply_v to_o i._o as_o a_o opiate_n it_o be_v of_o very_o uncertain_a and_o uneven_a effect_n when_o apply_v external_o for_o sometime_o it_o cause_v sleep_n take_v away_o pain_n but_o it_o often_o fail_v therefore_o it_o be_v general_o much_o better_a safe_a more_o certain_a and_o effectual_a to_o use_v it_o internal_o i_o do_v scarce_o know_v the_o case_n wherein_o it_o be_v better_a to_o use_v it_o external_o than_o internal_o unless_o it_o be_v to_o smell_v to_o in_o some_o case_n but_o of_o these_o thing_n more_o particular_o when_o we_o come_v to_o the_o use_v of_o opium_n in_o cure_v prevent_v or_o paliate_a disease_n for_o here_o we_o only_o lie_v down_o effect_n in_o order_n to_o a_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n to_o which_o its_o internal_a effect_n will_v main_o contribute_v however_o it_o may_v be_v very_o useful_a to_o that_o end_n to_o lay_v down_o its_o alterative_a effect_n for_o thereby_o we_o shall_v in_o good_a measure_n know_v the_o prin_fw-mi ciple_n by_o which_o it_o operate_v ii_o it_o be_v external_a effect_n as_o a_o alterative_a be_v these_o viz._n 1._o it_o incides_fw-la resolve_n and_o discuss_n 2._o it_o relax_n and_o mollify_v 3._o it_o maturate_v and_o suppurate_v 4._o it_o exulcerate_v or_o cause_n blister_n if_o it_o be_v very_o strong_a and_o apply_v to_o person_n of_o a_o fine_a texture_n where_o the_o skin_n be_v tender_a but_o this_o effect_n belong_v more_o proper_o to_o the_o maslack_n or_o true_a 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o drop_n from_o the_o incision_n make_v in_o the_o head_n of_o the_o poppy_n especial_o the_o theban_a which_o afford_v a_o very_a powerful_a juice_n hence_o you_o may_v observe_v that_o the_o more_o it_o exulcerates_n or_o blister_n the_o better_a be_v the_o opium_n &_o vice_fw-la versâ_fw-la 5._o it_o be_v a_o psilotherick_n for_o it_o prevent_v hair_n to_o grow_v and_o cause_v the_o shed_v thereof_o 6._o it_o be_v hurtful_a to_o the_o eye_n and_o ear_n 7._o it_o excite_v itch_n apply_v in_o a_o moderate_a manner_n to_o the_o skin_n 8._o it_o excite_v venery_n apply_v to_o the_o perinaeum_n chap._n iu._n the_o effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o the_o moderate_a do_v in_o ordinary_a use_n to_o produce_v the_o follow_a effect_n be_v from_o one_o to_o three_o grain_n more_o or_o less_o according_a to_o the_o circumstance_n condition_n case_n constitution_n age_n &c_n &c_n of_o the_o person_n who_o take_v it_o 2._o it_o operate_v general_o in_o a_o short_a time_n after_o it_o be_v in_o the_o stomach_n that_o be_v in_o about_o half_a a_o hour_n more_o or_o less_o if_o take_v in_o a_o liquid_a form_n and_o in_o about_o a_o hour_n more_o or_o less_o if_o in_o a_o solid_a form_n drink_v a_o draught_n of_o water_n or_o some_o liquor_n after_o it_o otherwise_o it_o may_v be_v sometime_o near_o a_o hour_n and_o a_o half_a before_o it_o have_v its_o full_a effect_n but_o the_o time_n of_o its_o operation_n have_v a_o considerable_a latitude_n according_a to_o the_o disposition_n of_o the_o stomach_n and_o other_o circumstance_n as_o the_o vehicle_n it_o be_v take_v in_o etc._n etc._n the_o constant_a effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o diffuse_v itself_o in_o a_o kind_n of_o indefinite_a manner_n seizing_z one_o not_o unlike_o the_o gentle_a sweet_a deliquium_fw-la that_o we_o find_v upon_o our_o entrance_n into_o a_o most_o agreeable_a slumber_n which_o upon_o yield_v to_o it_o general_o end_v in_o sleep_n but_o if_o the_o person_n keep_v himself_o in_o action_n discourse_n or_o business_n it_o seem_v especial_o when_o give_v in_o a_o mornning_a after_o a_o moderate_a rest_n at_o night_n like_o a_o most_o delicious_a and_o extraordinary_a refreshment_n of_o the_o spirit_n upon_o very_o good_a news_n or_o any_o other_o great_a cause_n of_o joy_n as_o the_o sight_n of_o a_o dear_o belove_a person_n etc._n etc._n thought_n to_o have_v be_v lose_v at_o sea_n or_o the_o like_a cause_v such_o a_o pleasant_a ovation_n of_o the_o spirit_n serenity_n etc._n etc._n as_o we_o find_v after_o a_o competent_a measure_n of_o generous_a wine_n ad_fw-la hilaritatem_fw-la as_o man_n use_v to_o say_v it_o be_v indeed_o so_o unexpressible_o fine_a and_o sweet_a a_o pleasure_n that_o it_o be_v very_o difficult_a for_o i_o to_o describe_v or_o any_o to_o conceive_v it_o but_o such_o as_o actual_o feel_v it_o for_o it_o be_v as_o if_o a_o good_a genius_n possess_v or_o inform_v a_o man_n therefore_o people_n do_v common_o call_v it_o a_o heavenly_a condition_n as_o if_o no_o worldly_a pleasure_n be_v to_o be_v compare_v with_o it_o helmontianus_fw-la will_v doubtless_o express_v it_o by_o the_o archaeus_n in_o his_o very_a best_a humour_n it_o have_v be_v compare_v not_o without_o good_a cause_n to_o a_o permanent_a gentle_a degree_n of_o that_o pleasure_n which_o modesty_n forbid_v the_o name_n of_o and_o it_o be_v well_o worth_a a_o remark_n that_o both_o be_v pleasure_n of_o the_o same_o sense_n viz._n that_o of_o feel_v for_o it_o can_v be_v a_o pleasure_n of_o any_o other_o sense_n since_o it_o be_v internal_a 2._o it_o cause_v a_o brisk_a gay_a and_o good_a humour_n nor_o do_v i_o doubt_v but_o it_o have_v this_o effect_n upon_o sleep_a person_n as_o far_o as_o their_o condition_n be_v capable_a of_o observe_v it_o for_o you_o shall_v have_v they_o often_o tell_v of_o pleasant_a dream_n after_o it_o when_o they_o remember_v they_o and_o speak_v of_o any_o see_v bauchin_n and_o the_o author_n mention_v below_o under_o the_o four_o effect_n of_o opium_n 3._o it_o cause_v promptitude_n serenity_n alacrity_n and_o expediteness_n in_o dispatch_v and_o manage_n of_o business_n to_o which_o end_n and_o that_o of_o a_o good_a and_o gay_a humour_n which_o be_v near_o of_o kind_n it_o be_v common_o take_v in_o the_o morning_n in_o the_o eastern_a country_n with_o most_o certain_a effect_n the_o truth_n of_o which_o wedelius_n be_v force_v to_o confess_v though_o quite_o contrary_a to_o his_o hypothesis_n of_o opium_n fix_v and_o coagulate_v the_o spirit_n give_v a_o instance_n of_o a_o certain_a serene_a person_n who_o when_o she_o have_v any_o affair_n of_o great_a moment_n to_o dispatch_v do_v beforehand_o take_v opium_n with_o great_a advantage_n for_o she_o thereby_o find_v herself_o every_o way_n better_o dispose_v for_o business_n and_o more_o enable_v to_o bear_v the_o fatigue_n thereof_o which_o be_v the_o substance_n of_o what_o he_o write_v in_o latin_n many_o other_o author_n confirm_v the_o truth_n of_o these_o effect_n but_o above_o all_o the_o constant_a experience_n of_o the_o eastern_a nation_n put_v it_o out_o of_o all_o doubt_n 4._o it_o cause_v assurance_n ovation_n of_o the_o spirit_n courage_n contempt_n of_o danger_n and_o magnanimity_n much_o after_o the_o manner_n that_o generous_a wine_n do_v instead_o of_o which_o the_o turk_n etc._n etc._n use_v opium_n before_o engagement_n desperate_a attack_n etc._n etc._n as_o be_v most_o notorious_a to_o make_v they_o courageous_a which_o it_o certain_o do_v for_o your_o satisfaction_n as_o to_o this_o and_o other_o effect_n of_o opium_n not_o so_o common_o observe_v
which_o give_v the_o occasion_n as_o you_o may_v remember_v to_o the_o hypothesis_n of_o its_o operate_n by_o fume_n rise_v out_o of_o the_o stomach_n because_o they_o can_v not_o think_v of_o any_o other_o mean_v by_o which_o it_o may_v affect_v the_o head_n brain_n animal_n spirit_n nerve_n etc._n etc._n while_o it_o be_v at_o stomach_n but_o by_o the_o way_n of_o fume_n or_o vapour_n it_o be_v therefore_o past_a all_o doubt_n that_o opium_n produce_v its_o common_a effect_n while_o it_o be_v at_o stomach_n and_o before_o it_o arrive_v at_o the_o blood_n and_o therefore_o do_v not_o operate_v as_o a_o alterative_a thereof_o second_o because_o a_o grain_n of_o opium_n which_o operate_v very_o remarkable_o bear_v as_o etmuller_n well_o observe_v so_o small_a a_o proportion_n to_o the_o blood_n that_o it_o can_v produce_v such_o great_a and_o notable_a effect_n as_o a_o alterative_a thereof_o for_o a_o grain_n of_o opium_n to_o 20_o pound_n of_o blood_n which_o a_o ordinary_a man_n have_v in_o his_o body_n be_v but_o as_o 1_o to_o 115200_o or_o if_o 16_o oucne_n be_v allow_v to_o the_o pound_n as_o 1_o to_o 153600._o but_o it_o be_v no_o wonder_n if_o a_o grain_n shall_v affect_v the_o membrane_n at_o stomach_n since_o the_o 1000_o part_n of_o a_o grain_n of_o the_o vomitory_n particle_n of_o crocus_n metallorum_fw-la or_o regulus_n of_o antimony_n do_v affect_v it_o so_o eminent_o as_o many_o other_o thing_n will_v in_o a_o very_a small_a quantity_n whereas_o the_o alter_n of_o the_o blood_n to_o any_o observable_a degree_n require_v the_o use_n of_o alterative_n in_o great_a quantity_n for_o several_a week_n which_o confirm_v the_o former_a conclusion_n that_o opium_n do_v not_o operate_v as_o a_o alterative_a as_o to_o its_o common_a and_o usual_a effect_n ii_o opium_n do_v not_o operate_v by_o grievous_a sensation_n or_o irritation_n as_o vomit_n purger_n errhine_n salivator_n or_o apophlegmatizer_n etc._n etc._n do_v first_o because_o it_o manifest_o cause_v a_o very_a agreeable_a pleasant_a and_o even_o charm_a sensation_n second_o because_o it_o take_v away_o grievous_a sensation_n or_o pain_n thereby_o stop_v vomit_v purge_v and_o all_o other-effect_n of_o grievous_a sensation_n by_o acrimony_n etc._n etc._n as_o for_o the_o vomit_v that_o opium_n sometime_o cause_n it_o be_v only_o as_o shall_v be_v show_v by_o its_o resinous_n part_n stick_v to_o the_o coat_n of_o the_o stomach_n which_o be_v separate_v from_o it_o opium_n have_v no_o such_o effect_n though_o all_o its_o good_a effect_n remain_v so_o its_o purge_v which_o happen_v most_o rare_o and_o only_o when_o a_o great_a quantity_n be_v give_v to_o man_n of_o strong_a digestion_n it_o be_v only_o from_o its_o rosin_n digest_v and_o resolve_v in_o strong_a stomach_n hence_o it_o be_v that_o dog_n and_o such_o as_o have_v canine_a appetite_n do_v general_o purge_v after_o a_o great_a quantity_n of_o crude_a or_o rosinous_n opium_n whereas_o such_o as_o be_v not_o rosinous_n cause_v no_o such_o effect_n but_o of_o these_o matter_n more_o to_o your_o satisfaction_n hereafter_o three_o because_o it_o cause_v all_o effect_n that_o be_v quite_o contrary_a to_o those_o of_o grievous_a sensation_n it_o cause_v a_o ovation_n of_o the_o sensitive_a soul_n and_o spirit_n pain_n or_o grievous_a sensation_n a_o depression_n of_o spirit_n it_o cause_v euphory_n and_o pain_n weariness_n for_o what_o tire_v more_o than_o pain_n or_o labour_v in_o pain_n it_o cause_v good_a humour_n pain_n peevishness_n fretfulness_n and_o ill_a humour_n opium_n cause_v relaxation_n of_o all_o part_n pain_n contraction_n that_o cause_v free_a perspiration_n this_o check_v it_o that_o cause_v sleep_n this_o hinder_v it_o that_o cause_v contentation_n acquiescence_n this_o discontent_n and_o uneasiness_n that_o compose_v this_o discompose_v the_o spirit_n blood_n etc._n etc._n that_o cause_v flux_n by_o irritation_n etc._n etc._n this_o moderate_n or_o stop_v they_o that_o open_v the_o pore_n pain_n constr_v they_o opium_n prevent_v the_o shake_v fit_n in_o ague_n pain_n bring_v they_o on_o that_o cause_v a_o large_a and_o slow_a pulse_n this_o a_o quick_a hard_a and_o narrow_a pulse_n that_o cause_v a_o efflorescence_n of_o the_o skin_n this_o paleness_n that_o pleasant_a this_o unpleasant_a dream_n that_o still_v hiccough_n this_o cause_n they_o that_o take_v off_o contraction_n convulsion_n etc._n etc._n this_o cause_v they_o to_o be_v short_a opium_n cause_v all_o the_o effect_n of_o pleasant_a sensation_n and_o take_v off_o all_o the_o effect_n of_o grievous_a sensation_n what_o can_v be_v a_o more_o evident_a proof_n of_o its_o act_n by_o cause_v a_o pleasant_a sensation_n it_o be_v endless_a to_o mention_v all_o the_o proof_n that_o may_v be_v make_v to_o the_o same_o purpose_n from_o pleaser_n and_o displeaser_n of_o sensation_n therefore_o we_o fair_o conclude_v that_o opium_n do_v not_o operate_v by_o cause_v a_o grievovi_fw-la sensation_n and_o there_o be_v no_o other_o way_n leave_v by_o which_o it_o may_v operate_v it_o must_v operate_v by_o cause_v a_o pleasant_a sensation_n which_o be_v the_o true_a and_o plain_a reason_n why_o as_o have_v be_v show_v it_o take_v off_o pain_n and_o cause_v all_o effect_n quite_o contrary_a to_o that_o of_o grievous_a sensation_n irritation_n by_o acrimony_n etc._n etc._n which_o be_v most_o eminent_a upon_o the_o most_o sensible_a part_n as_o the_o stomach_n intestine_n venereal_a membrane_n skin_n etc._n etc._n as_o you_o may_v observe_v where_o the_o effect_n of_o opium_n be_v enumerate_v now_o gentle_a reader_n consider_v that_o contrary_n be_v the_o true_a cure_n of_o contrary_n what_o can_v then_o cure_v pain_n and_o all_o its_o effect_n better_a than_o pleasure_n it_o be_v very_o strange_a then_o that_o million_o for_o many_o age_n find_v opium_n cure_v or_o take_v off_o pain_n and_o all_o its_o effect_n above_o all_o thing_n shall_v not_o attribute_v its_o so_o do_v to_o its_o cause_v a_o pleasant_a sensation_n which_o be_v the_o direct_a contrary_n to_o pain_n especial_o since_o every_o man_n that_o take_v opium_n feel_v a_o actual_a pleasure_n upon_o take_v thereof_o pleasant_a dream_n a_o pleasant_a humour_n etc._n etc._n it_o may_v be_v say_v what_o if_o it_o be_v grant_v that_o opium_n operate_v by_o a_o please_a sensation_n which_o i_o will_v thank_v none_o for_o that_o have_v feel_v at_o stomach_n or_o reason_n at_o brain_n how_o be_v it_o possible_a that_o such_o pleasant_a sensation_n shall_v cause_v and_o explicate_v all_o the_o various_a strange_a wonderful_a mysterious_a and_o very_o often_o seem_o contradictory_n phenomena_n and_o effect_n of_o opium_n answer_n as_o easy_o as_o ever_o i_o explain_v any_o thing_n in_o nature_n especial_o if_o my_o tract_n of_o animal_n mechanism_n be_v publish_v but_o it_o be_v my_o misfortune_n that_o it_o be_v not_o however_o it_o shall_v not_o be_v the_o reader_n though_o it_o will_v put_v i_o to_o a_o great_a trouble_n to_o evade_v which_o be_v none_o of_o my_o intention_n by_o those_o word_n but_o rather_o to_o bespeak_v the_o reader_n be_v patience_n while_n i_o be_o premise_v some_o necessary_a praecognita_fw-la requisite_a to_o be_v know_v before_o i_o enter_v upon_o the_o explication_n of_o the_o wonderful_a and_o seem_o inexplicable_a effect_n of_o opium_n i_o therefore_o desire_v the_o reader_n be_v leave_v to_o premise_v some_o thing_n of_o the_o nature_n of_o sensation_n and_o sensitive_a pleasure_n in_o order_n to_o his_o more_o clear_a and_o ready_a understanding_n my_o explication_n of_o this_o mysterious_a and_o momentous_a matter_n look_v upon_o as_o so_o dark_a and_o abstruse_a a_o business_n to_o this_o day_n that_o some_o have_v not_o only_o yield_v it_o up_o as_o a_o thing_n hide_v from_o mankind_n but_o have_v earnest_o and_o serious_o argue_v that_o it_o act_v absolute_o by_o a_o occult_a quality_n reserve_v in_o a_o special_a manner_n as_o be_v the_o nature_n of_o spirit_n from_o our_o knowledge_n that_o it_o have_v be_v so_o hitherto_o i_o think_v none_o can_v deny_v as_o the_o circulation_n of_o the_o blood_n be_v for_o thousand_o of_o year_n though_o the_o very_a motion_n be_v see_v by_o million_o so_o as_o the_o cause_n of_o the_o operation_n of_o opium_n have_v be_v feel_v by_o a_o far_o great_a number_n it_o therefore_o will_v if_o i_o fail_v not_o in_o explain_v it_o appear_v so_o clear_a that_o it_o will_v be_v much_o wonder_v at_o like_o that_o of_o the_o circulation_n of_o the_o blood_n why_o so_o obvious_a a_o thing_n be_v not_o find_v by_o every_o one_o that_o use_v opium_n but_o whatever_o opium_n be_v god_n method_n be_v unsearchable_a and_o often_o his_o wise_a providence_n bestow_v good_a gift_n upon_o the_o unworthy_a that_o his_o free_a goodness_n may_v appear_v to_o who_o be_v all_o glory_n praise_n and_o thanksgiving_n for_o ever_o and_o ever_o amen_n note_v that_o while_o i_o be_o upon_o the_o
which_o argue_v that_o the_o specific_a combination_n of_o the_o oily_a and_o volatile_a part_n baffle_v all_o coction_n digestion_n circulation_n and_o percolation_n that_o have_v happen_v in_o the_o body_n dioscorides_n and_o aeginela_fw-la speak_v of_o opium_n say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o be_v the_o smell_n of_o the_o medicament_n be_v expanded_a over_o the_o whole_a body_n which_o thing_n of_o its_o nature_n do_v as_o garlic_n onion_n semen_n animale_a which_o cause_v rankness_n all_o over_o male_a creature_n as_o ram_n boar_n bull_n etc._n etc._n 14._o le_fw-fr febure_n in_o his_o chemistry_n part_v 2._o p._n 33_o say_v that_o opium_n have_v a_o volatile_a salt_n inseparable_o mix_v with_o sulphur_n or_o oily_a part_n 15._o wedelius_n in_o his_o opiologia_fw-la lib._n 2._o sect._n 1_o cap._n 4._o p._n 91._o speak_v of_o opium_n say_v sal_fw-la ejus_fw-la cum_fw-la sulphur_n intime_fw-la combinatum_fw-la sudores_fw-la efficit_fw-la that_o be_v its_o salt_n be_v intimate_o combine_v with_o sulphur_n or_o oil_n cause_v sweat_n and_o lib._n 2._o p._n 143._o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d obtinuit_fw-la non_fw-la facile_fw-la dissipabilem_fw-la that_o be_v it_o have_v a_o contexture_n not_o easy_o dissipable_a 18._o all_o know_v how_o apt_a volatile_a salt_n and_o oily_a part_n be_v to_o combine_v therefore_o opium_n act_n and_o produce_v its_o usual_a good_a effect_n by_o a_o sal-volatile-oleosum_a somewhat_o more_o active_a than_o that_o in_o our_o membrane_n who_o principle_n be_v most_o intimate_o and_o strict_o combine_v and_o so_o that_o it_o be_v qualify_v in_o the_o high_a degree_n for_o our_o purpose_n because_o 1._o it_o agree_v in_o principle_n with_o our_o membrane_n 2._o that_o its_o sal-volatile-oleosum_a be_v more_o active_a and_o vigorous_a than_o that_o of_o the_o membrane_n to_o actuate_v and_o excite_v the_o spiritus_fw-la insiti_fw-la and_o fine_o to_o tickle_v and_o gratify_v the_o membrane_n 3._o that_o the_o volatile_a salt_n and_o oily_a part_n be_v so_o intimate_o combine_v do_v delicious_o qualify_v one_o the_o other_o for_o that_o purpose_n while_o the_o oily_a smooth_v and_o lenify_v the_o volatile_a salt_n and_o the_o volatile_a salt_n actuate_v and_o quicken_v the_o oily_a and_o that_o be_v so_o combine_v 4._o both_o conspire_v to_o a_o permanent_a and_o exalt_a pleasure_n of_o the_o membrane_n especial_o at_o stomach_n and_o the_o venereal_a part_n where_o they_o be_v so_o exquisite_o dispose_v for_o sensation_n therefore_o the_o sal-volatile-oleosum_a of_o opium_n separate_v from_o its_o rosin_n be_v most_o consummate_a and_o best_a qualify_v that_o possible_o can_v be_v imagine_v to_o please_v gratify_v and_o fine_o to_o titillate_v our_o membrane_n or_o organ_n of_o sensation_n which_o be_v the_o thing_n require_v i_o can_v better_o illustrate_v its_o nature_n than_o by_o the_o most_o exalt_a thing_n in_o a_o animal_n viz._n it_o be_v semen_n therefore_o for_o confirmation_n of_o its_o principle_n and_o excellency_n therein_o i_o will_v consider_v its_o likeness_n and_o agreement_n therewith_o 1._o in_o be_v both_o a_o shall_v volatile-oleosum_a 2._o in_o have_v a_o more_o active_a vigorous_a and_o exalt_v sal-volatile-oleosum_a than_o any_o part_n of_o the_o animal_n 3._o in_o have_v the_o volatile_a salt_n and_o oleous_a particle_n intimate_o combine_v for_o semen_n animale_a will_v as_o opium_n keep_v very_o long_o uncorrupted_a as_o appear_v by_o its_o long_a stay_n in_o the_o vesiculae_fw-la seminales_fw-la of_o some_o animal_n that_o do_v not_o excern_v it_o in_o many_o year_n 4._o in_o that_o both_o be_v apt_a to_o mix_v with_o all_o fort_n of_o menstruum_n and_o both_o mole_n minimum_n virtute_fw-la maxima_fw-la 5._o in_o have_v much_o the_o same_o smell_n viz._n a_o rank_n and_o vehement_a one_o 6._o in_o taint_v the_o body_n therewith_o as_o have_v be_v show_v 7._o in_o be_v much_o of_o the_o same_o weight_n as_o appear_v by_o both_o sink_n in_o water_n etc._n etc._n 8._o the_o taste_n must_v in_o all_o probability_n have_v a_o rankness_n in_o it_o like_o that_o of_o opium_n because_o it_o give_v a_o rank_a taste_n to_o the_o whole_a body_n of_o male_a creature_n 9_o both_o excite_v venery_n cause_n erection_n venereal_a fury_n and_o nocturnal_a pollution_n etc._n etc._n 10._o both_o cause_n boldness_n courage_n and_o magnanimity_n which_o be_v reckon_v among_o the_o effect_n of_o opium_n and_o be_v the_o common_a effect_n of_o plenitude_n of_o seed_n in_o animal_n that_o be_v otherwise_o pusillanimous_a in_o time_n of_o copulation_n so_o modest_a and_o sheepish_a boy_n grow_v much_o more_o assure_v â—old_a and_o as_o they_o common_o call_v it_o manlike_a upon_o puberty_n and_o girl_n grow_v more_o womanlike_a in_o their_o disposition_n and_o it_o be_v my_o observation_n that_o the_o man_n who_o breed_v most_o of_o the_o sem._n virile_a be_v general_o if_o not_o always_o the_o most_o valiant_a 11._o both_o do_v cause_n a_o great_a relaxation_n upon_o the_o pleasure_n thereof_o as_o appear_v after_o a_o good_a do_v of_o opium_n and_o upon_o emission_n of_o the_o other_o by_o the_o deadness_n of_o the_o eye_n or_o laxity_n of_o the_o cornea_n in_o both_o case_n dilatation_n of_o the_o pupil_n floridity_n of_o the_o skin_n large_a perspiration_n laxity_n of_o the_o limb_n sleepiness_n loss_n of_o memory_n and_o sense_n alienation_n of_o the_o mind_n a_o wide_a pulse_n indolence_n loss_n of_o feel_v in_o both_o case_n and_o other_o sign_n of_o relaxation_n 12._o both_o opium_n and_o puberty_n cause_v a_o growth_n of_o the_o penis_n breast_n and_o increase_v milk_n by_o reason_n of_o the_o relaxation_n that_o they_o cause_n which_o as_o in_o sleep_n cause_v the_o great_a nutrition_n but_o of_o the_o manner_n how_o it_o happen_v upon_o relaxation_n more_o hereafter_o if_o there_o be_v occasion_n hence_o it_o be_v 13._o that_o both_o opium_n and_o puberty_n be_v apt_a to_o bring_v down_o the_o menses_fw-la and_o open_v the_o viae_fw-la by_o the_o relaxation_n and_o that_o marriage_n or_o the_o pleasure_n of_o venereal_a act_n do_v by_o the_o like_a relaxation_n promote_v the_o menses_fw-la that_o both_o opium_n and_o such_o act_n be_v apt_a to_o cause_n miscarriage_n by_o relax_v the_o neck_n of_o the_o womb_n etc._n etc._n 14._o both_o cause_n sadness_n and_o dejection_n when_o the_o operation_n be_v over_o as_o indeed_o pleasure_n general_o do_v especial_o if_o intense_a 15._o both_o opium_n and_o sem._n animale_a prevent_v lassitude_n and_o cause_n euphory_n or_o easy_a undergo_n of_o labour_n hence_o it_o be_v that_o stone_n horse_n will_v not_o be_v so_o soon_o tire_v when_o full_a thereof_o and_o quick_o recover_v if_o tire_a which_o may_v doubtless_o be_v observe_v in_o other_o animal_n but_o that_o they_o be_v not_o use_v to_o labour_n and_o so_o not_o obvious_a to_o be_v observe_v 16._o author_n do_v say_v that_o sem._n virile_a take_v of_o venereal_a impotence_n procure_v love_n etc._n etc._n which_o doubtless_o must_v be_v by_o exciting_a to_o venery_n as_o opium_n do_v thus_o the_o genitals_o of_o buck_n boar_n buck_n of_o hare_n cock_n etc._n etc._n do_v as_o opium_n excite_v venery_n and_o the_o seed_n of_o animal_n as_o of_o a_o camel_n and_o the_o aforesaid_a creature_n come_v to_o be_v esteem_v hypnotick_n and_o doubtless_o all_o animal_n seed_n especial_o of_o the_o more_o salaceous_a creature_n be_v a_o opiate_n in_o some_o degree_n to_o be_v short_a the_o main_a if_o not_o all_o the_o difference_n in_o their_o effect_n arise_v only_o 1._o from_o the_o different_a part_n that_o they_o affect_v because_o opium_n affect_v the_o stomach_n the_o venereal_a and_o all_o the_o membrane_n in_o general_a and_o sem._n animale_a only_a the_o venereal_a part_n immediate_o though_o a_o intense_a pleasure_n of_o one_o part_n do_v affect_v the_o whole_a 2._o that_o opium_n do_v affect_v with_o a_o sense_n of_o pleasure_n more_o permanent_a viz._n for_o many_o hour_n as_o have_v be_v say_v and_o that_o the_o pleasure_n of_o the_o other_o be_v momentary_a therefore_o opium_n act_n by_o cause_v a_o intense_a permanent_a and_o charm_a pleasure_n of_o the_o membrane_n in_o general_a but_o more_o particular_o of_o the_o stomach_n and_o venereal_a part_n as_o be_v more_o exquisite_o dispose_v for_o sensation_n for_o the_o preservation_n of_o the_o individuum_fw-la and_o species_n it_o can_v be_v much_o wonder_v at_o consider_v our_o active_a principle_n be_v a_o sal-volatile-oleosum_a and_o that_o opium_n be_v such_o and_o that_o we_o natural_o carry_v a_o opiate_n within_o we_o that_o in_o some_o case_n our_o ordinary_a sal-volatile-oleosum_a or_o that_o of_o the_o choler_n semen_n etc._n etc._n be_v by_o some_o accident_n exalt_v towards_o the_o nature_n of_o opium_n may_v have_v the_o effect_v of_o a_o opiate_n upon_o we_o by_o cause_v sopor_n and_o lethargic_a distemper_n fuâ—or_fw-la uterinus_fw-la by_o titillation_n etc._n etc._n thus_o the_o spume_n of_o some_o male_a animal_n mummy_n etc._n etc._n
and_o motion_n fail_v together_o of_o the_o great_a perspiration_n and_o all_o other_o effect_n of_o relaxation_n in_o such_o syncopes_fw-la or_o leipothymy_n in_o a_o yet_o high_o degree_n than_o in_o sleep_n wherein_o the_o sensitive_a soul_n do_v not_o quite_o let_v go_v the_o reign_v of_o contraction_n as_o appear_v by_o the_o motion_n that_o remain_v as_o of_o the_o heart_n intestine_n etc._n etc._n though_o far_o more_o remiss_a in_o sleep_n than_o in_o a_o wake_v state_n note_v that_o such_o leipothymy_n be_v as_o be_v hint_v of_o the_o same_o nature_n as_o sleep_n be_v but_o that_o they_o be_v sudden_a more_o profound_a and_o not_o so_o usual_a natural_a and_o of_o course_n as_o sleep_n be_v which_o make_v they_o more_o amaze_a and_o surprise_v therefore_o it_o follow_v that_o they_o be_v as_o sleep_n be_v a_o mean_n of_o recruit_v when_o all_o work_n and_o tug_v by_o defensive_a contraction_n fail_v and_o so_o the_o last_o refuge_n of_o the_o sensitive_a soul_n when_o overtired_n in_o order_n to_o recover_v strength_n for_o a_o fresh_a engagement_n with_o the_o enemy_n as_o be_v tire_v at_o night_n the_o sensitive_a soul_n loosen_v the_o rign_n of_o contraction_n to_o enable_v he_o the_o better_a to_o fall_v to_o his_o work_n the_o next_o day_n this_o you_o will_v find_v by_o all_o reason_n and_o experience_n to_o be_v the_o true_a state_n of_o leipothymy_n upon_o grievance_n and_o fatigue_n though_o not_o hitherto_o mind_v that_o i_o know_v of_o many_o true_a and_o useful_a consequence_n do_v hence_o follow_v as_o that_o we_o be_v not_o always_o to_o disturb_v they_o or_o put_v they_o out_o of_o these_o recruit_v leipothymy_n by_o grievous_a mean_n as_o pricking_n pinch_n etc._n etc._n but_o only_o by_o cordial_n and_o refresh_a thing_n as_o you_o will_v treat_v a_o person_n much_o tire_v or_o by_o let_v they_o take_v their_o nap_n if_o i_o may_v so_o call_v it_o if_o there_o be_v not_o very_o eminent_a danger_n but_o it_o be_v endless_a and_o beside_o my_o purpose_n to_o make_v a_o particular_a discourse_n of_o this_o matter_n which_o will_v belong_v more_o proper_o to_o my_o tract_n of_o animal_n mechanism_n 14._o death_n happen_v sometime_o though_o very_o rare_o and_o that_o in_o very_o weak_a people_n that_o take_v little_a or_o no_o sustenance_n because_o either_o when_o fall_v into_o such_o syncopes_fw-la they_o never_o come_v out_o of_o they_o by_o reason_n that_o they_o have_v not_o within_o they_o wherewith_o to_o recruit_v their_o spirit_n or_o that_o opium_n take_v they_o much_o spend_v and_o tire_v with_o distemper_n cause_n as_o in_o weak_a and_o weary_a people_n a_o most_o profound_a sopor_fw-la which_o not_o recruit_v they_o who_o take_v or_o digest_v no_o sustenance_n they_o must_v rather_o grow_v weak_a and_o weak_a for_o somewhat_o be_v spend_v while_o we_o live_v and_o consequent_o the_o sleep_n or_o sopor_fw-la more_o and_o more_o profound_a till_o they_o sleep_v their_o last_o for_o want_v of_o some_o recruit_v which_o be_v the_o very_a thing_n that_o natural_o lessen_v sleep_n and_o awake_v we_o when_o there_o be_v no_o other_o apparent_a cause_n for_o as_o the_o be_v tire_v and_o want_v of_o recruit_v cause_n sleep_v so_o the_o have_v it_o cause_v wake_v or_o which_o be_v the_o same_o in_o effect_n no_o far_o need_v of_o relaxation_n for_o recruit_n sake_n so_o that_o the_o sensitive_a soul_n fall_v to_o his_o useful_a work_n of_o vigilative_a contraction_n for_o sense_n and_o motion_n sake_n 15._o it_o sometime_o cause_n purge_v which_o happen_v as_o far_o as_o i_o have_v observe_v or_o can_v learn_v only_o when_o it_o be_v give_v in_o a_o good_a quantity_n to_o person_n of_o a_o strong_a digestion_n or_o canine_a appetite_n the_o case_n be_v thus_o when_o person_n that_o be_v of_o a_o strong_a digestion_n take_v a_o resinous_n opiate_n in_o good_a quantity_n they_o do_v in_o great_a measure_n by_o their_o fix_a salt_n at_o stomach_n and_o strong_a digestion_n subdue_v the_o volatility_n of_o the_o opium_n and_o dissolve_v its_o rosin_n which_o then_o as_o acrimonious_a rosin_n or_o vomit_n subdue_v by_o fix_a salt_n use_v to_o do_v cause_v purge_v hence_o it_o be_v that_o it_o general_o if_o not_o always_o purge_v dog_n and_o people_n of_o a_o high_a canine_a appetite_n and_o that_o sometime_o meet_v such_o fix_a salt_n it_o purge_v the_o consumptive_a bartholine_n say_v that_o mandrake_n juice_n purge_v when_o it_o meet_v with_o acrimonious_a fix_a salt_n erastus_n and_o quercelan_n do_v agree_v that_o it_o have_v a_o purgative_n quality_n but_o that_o it_o do_v not_o always_o exert_v it_o 1._o because_o it_o take_v away_o the_o sense_n of_o irritation_n 2._o because_o it_o be_v give_v in_o too_o small_a a_o quantity_n the_o reason_n be_v just_a and_o right_a and_o not_o only_o consistent_a with_o but_o confirm_v what_o i_o say_v note_v that_o this_o be_v not_o intend_v of_o the_o purge_v that_o happen_v after_o the_o declination_n of_o its_o operation_n which_o be_v as_o you_o will_v find_v from_o another_o cause_n therefore_o this_o do_v not_o smell_v of_o the_o opium_n as_o the_o other_o do_v because_o it_o be_v past_a and_o go_v before_o that_o in_o the_o declination_n happen_v of_o which_o more_o in_o its_o proper_a place_n 16._o it_o raise_v and_o revive_v some_o person_n that_o be_v almost_o expire_a in_o two_o case_n one_o be_v when_o such_o as_o have_v be_v use_v to_o take_v it_o be_v even_o expire_a for_o want_n of_o it_o of_o which_o more_o hereafter_o the_o other_o case_n be_v when_o violent_a contraction_n as_o from_o pain_n cold_a vomit_n and_o grievous_a passion_n as_o terror_n etc._n etc._n be_v the_o cause_n that_o people_n be_v almost_o expire_a for_o it_o take_v off_o the_o contraction_n by_o relax_v etc._n etc._n 17._o it_o stay_v very_o long_o at_o stomach_n when_o the_o rosin_n thereof_o stick_v to_o the_o stomach_n and_o be_v there_o detain_v beside_o that_o the_o stomach_n be_v relax_v and_o have_v little_a sense_n or_o motion_n as_o in_o sleep_n do_v not_o soon_o digest_v it_o or_o discharge_v it_o it_o be_v fine_a in_o this_o case_n and_o all_o other_o to_o observe_v how_o sensation_n and_o motion_n go_v hand_n in_o hand_n keep_v equal_a pace_n and_o equal_a proportion_n as_o it_o plain_o must_v be_v by_o the_o principle_n of_o relaxation_n and_o contraction_n which_o i_o have_v state_v and_o prove_v 18._o it_o cause_v stoppage_n of_o urine_n sometime_o especial_o in_o old_a people_n by_o over_o relax_v and_o cause_v a_o kind_n of_o a_o temporary_a palsy_n of_o the_o bladder_n as_o be_v show_v and_o take_v away_o the_o sense_n of_o the_o irritation_n of_o the_o urine_n which_o shall_v contract_v the_o bladder_n to_o squeeze_v it_o out_o by_o which_o mean_v it_o happen_v sometime_o that_o the_o bladder_n come_v to_o be_v so_o over_o extend_v beyond_o its_o due_a tone_n that_o they_o can_v contract_v it_o to_o make_v water_n in_o all_o which_o case_n strong_a contracter_n as_o cold_a terror_n etc._n etc._n immediate_o cure_v they_o the_o very_a put_v the_o scrotum_fw-la to_o the_o edge_n of_o a_o cold_a chamberpot_n have_v effect_v it_o several_a time_n by_o my_o advice_n though_o if_o need_v be_v you_o must_v come_v to_o dash_v of_o cold_a water_n upon_o the_o region_n of_o the_o bladder_n or_o pump_v on_o it_o or_o dip_v in_o it_o etc._n etc._n so_o terror_n and_o cause_v a_o very_a smart_n pain_n especial_o near_o those_o part_n will_v do_v much_o but_o cold_a be_v the_o ready_a and_o best_a remedy_n 19_o it_o sometime_o prove_v dangerous_a after_o great_a hemorrbage_n or_o evacuation_n as_o tapping_n in_o dropsy_n etc._n etc._n because_o the_o relaxation_n hinder_v the_o part_n due_o to_o contract_v upon_o what_o remain_v which_o may_v cause_v great_a mischief_n as_o discontinuation_n of_o motion_n etc._n etc._n thus_o have_v you_o all_o the_o constant_a frequent_a and_o rare_a effect_n of_o opium_n take_v internal_o in_o a_o moderate_a do_v so_o natural_o easy_o plain_o and_o mechanical_o explicate_v that_o people_n may_v in_o my_o judgement_n more_o admire_v how_o all_o fail_v of_o discover_v the_o manner_n of_o their_o production_n than_o that_o i_o find_v it_o as_o man_n be_v apt_a to_o think_v of_o the_o circulation_n of_o the_o blood_n which_o now_o as_o i_o hope_v the_o effect_n of_o opium_n do_v seem_v very_o obvious_a both_o which_o case_n be_v to_o i_o very_o strong_a argument_n of_o a_o be_v that_o rule_n and_o dispose_n darken_v and_o illuminate_v etc._n etc._n as_o he_o please_v when_o i_o consider_v that_o both_o the_o circulation_n of_o the_o blood_n and_o the_o cause_n of_o the_o operation_n of_o opium_n viz._n pleasure_n at_o stomach_n etc._n etc._n fall_v under_o the_o sense_n of_o many_o million_o who_o in_o one_o case_n see_v the_o blood_n move_v and_o in_o the_o other_o feel_v
and_o alteration_n in_o a_o animal_n this_o helmont_n couch_v under_o the_o name_n of_o please_v the_o archaeus_n 3._o that_o it_o shall_v take_v away_o all_o grievance_n of_o the_o sensitive_a soul_n or_o archaeus_n because_o its_o grievance_n be_v the_o essential_a form_n of_o disease_n for_o even_o morbid_v matter_n unless_o it_o cause_v a_o grievance_n cause_v no_o more_o disease_n than_o it_o do_v in_o a_o dead_a carcase_n as_o helmont_n and_o common_a reason_n assure_v we_o therefore_o disease_n and_o grievance_n be_v only_o two_o word_n signify_v the_o same_o thing_n and_o nothing_o be_v capable_a of_o grievance_n in_o a_o animal_n as_o such_o but_o the_o sensitive_a soul_n 4._o it_o shall_v compose_v comfort_n enliven_v encourage_v and_o invigorate_v our_o sensitive_a soul_n and_o spirit_n as_o be_v the_o principle_n of_o motion_n in_o our_o animal_n nature_n in_o order_n to_o self_n preservation_n for_o nature_n or_o those_o active_a principle_n within_o we_o be_v the_o curer_n of_o disease_n and_o we_o physician_n only_a its_o minister_n to_o offer_v it_o good_a mean_n etc._n etc._n 5._o the_o principle_n of_o a_o panacea_fw-la shall_v be_v agreeable_a to_o the_o best_a noble_a most_o active_a and_o predominant_a principle_n of_o our_o body_n 6._o those_o principle_n in_o the_o panacea_fw-la shall_v be_v more_o vigorous_a than_o we_o to_o reduce_v they_o when_o deficient_a and_o exalt_v they_o when_o depress_v clog_v etc._n etc._n 7._o it_o shall_v be_v a_o general_a resolver_n of_o humour_n for_o which_o cause_n the_o liquor_n alcahe_o be_v so_o much_o extol_v for_o a_o panacea_fw-la hear_v what_o the_o great_a physician_n claudius_n de_fw-fr la_fw-fr courvee_n say_v uni_fw-la morbosae_fw-la &_o semper_fw-la preter_fw-la naturam_fw-la humorum_fw-la coagulationi_fw-la unique_fw-la eorundem_fw-la colliquationi_fw-la ovi_fw-fr perpetuo_fw-la intendit_fw-la natura_fw-la diligenter_n studeas_fw-la huius_fw-la adjuvandae_fw-la illius_fw-la corrigendae_fw-la modum_fw-la si_fw-la assecutus_fw-la fuâ—ris_fw-la habebis_fw-la in_o praxi_fw-la secretum_fw-la onmi_fw-la auro_fw-la potabili_fw-la omnique_fw-la antidoto_fw-la prestantius_fw-la denique_fw-la plus_fw-la poteris_fw-la in_o praxi_fw-la quam_fw-la si_fw-la cursus_fw-la astrorum_fw-la metallorum_fw-la vires_fw-la aut_fw-la totam_fw-la callueris_fw-la panaceam_fw-la 8._o it_o shall_v after_o such_o resolution_n of_o humour_n compose_v concentrate_v combine_v and_o unite_v the_o good_a principle_n 9_o it_o shall_v discuss_v the_o bad_a and_o useless_a part_n 10._o it_o shall_v open_v the_o pore_n to_o give_v they_o their_o exit_fw-la by_o that_o most_o universal_a natural_a plentiful_a kind_o and_o easy_a evacuation_n 11._o that_o after_o all_o it_o shall_v like_o the_o liquor_n alcahest_n remain_v very_o much_o unaltered_a in_o itself_o now_o whatsoever_o be_v endue_v with_o these_o eleven_o most_o noble_a qualification_n must_v be_v in_o the_o estimation_n of_o any_o rational_a physician_n or_o philosopher_n a_o glorious_a panacea_fw-la that_o be_v fit_v to_o take_v off_o the_o matter_n and_o form_n of_o all_o disease_n or_o grievance_n as_o far_o as_o it_o be_v in_o the_o power_n of_o a_o natural_a medicament_n or_o alterative_a so_o to_o do_v therefore_o let_v we_o see_v how_o the_o pure_a sal-volatile-oleosum_a of_o opium_n be_v furnish_v therewith_o 1._o it_o be_v so_o high_o agreeable_a and_o please_a to_o our_o most_o nice_a sensation_n at_o stomach_n which_o be_v give_v we_o for_o a_o touchstone_n watch_z and_o judge_n of_o what_o be_v agreeable_a and_o beneficial_a to_o our_o body_n that_o nothing_o in_o the_o whole_a world_n be_v so_o agreeable_a and_o please_a to_o it_o and_o therefore_o nothing_o be_v more_o agreeable_a and_o beneficial_a to_o our_o animal_n nature_n it_o will_v imply_v a_o contradiction_n that_o the_o stomach_n which_o be_v give_v we_o and_o according_o qualfy_v to_o make_v a_o true_a report_n of_o what_o be_v or_o be_v not_o agreeable_a and_o beneficial_a to_o we_o shall_v always_o though_o it_o may_v by_o accident_n possible_o give_v we_o a_o false_a report_n of_o the_o agreeableness_n of_o thing_n it_o will_v be_v more_o than_o profaneness_n to_o attribute_v such_o deceitful_a unkind_a and_o unwise_a contrivance_n to_o the_o infinite_o good_a and_o wise_a therefore_o the_o stomach_n do_v infallible_o testify_v and_o assure_v we_o that_o it_o be_v most_o agreeable_a to_o our_o nature_n see_v it_o be_v always_o so_o to_o it_o agreeableness_n and_o disagreeableness_n with_o which_o be_v appoint_v and_o ordain_v by_o god_n and_o nature_n to_o be_v the_o test_n and_o touchstone_n of_o what_o be_v agreeable_a or_o otherwise_o to_o our_o animal_n nature_n obj._n why_o then_o be_v so_o agreeable_a to_o the_o stomach_n shall_v it_o not_o create_v a_o appetite_n but_o rather_o lessen_v it_o ans._n though_o some_o may_v be_v so_o weak_a as_o to_o make_v such_o a_o objection_n because_o thing_n agreeable_a to_o the_o stomach_n be_v common_o repute_v to_o cause_v a_o appetite_n yet_o the_o matter_n due_o consider_v the_o case_n be_v quite_o contrary_a for_o appetite_n or_o hunger_n be_v a_o grievous_a sensation_n at_o stomach_n which_o can_v be_v expect_v from_o thing_n that_o gratify_v and_o please_v the_o stomach_n which_o be_v the_o adequate_a cure_n of_o a_o grievous_a sensation_n or_o hunger_n thus_o meat_n and_o drink_n as_o have_v be_v show_v cure_v a_o appetite_n grievous_a sensation_n or_o hunger_n thus_o wine_n and_o opium_n do_v by_o please_v the_o stomach_n cure_v a_o canine_a appetite_n etc._n etc._n therefore_o you_o may_v note_v by_o the_o by_o that_o all_o meat_n and_o drink_n that_o please_v the_o stomach_n and_o gratify_v its_o sense_n be_v real_o opiate_n in_o some_o degree_n cause_v good_a humour_n sleepiness_n etc._n etc._n appetite_n or_o hunger_n though_o it_o be_v a_o convenient_a call_n or_o intimation_n of_o want_n of_o supply_n and_o recruit_v be_v as_o such_o a_o consequent_a of_o defect_n and_o so_o unnatural_a though_o call_v natural_a because_o it_o be_v a_o thing_n that_o happen_v of_o course_n to_o direct_v we_o how_o to_o proportion_v thing_n to_o the_o exigence_n of_o nature_n of_o which_o there_o will_v be_v no_o need_n if_o we_o can_v otherwise_o proportion_v good_a and_o agreeable_a refection_n to_o our_o want_n thereof_o in_o short_a it_o be_v a_o disease_n which_o thing_n agreeable_a and_o please_a to_o the_o stomach_n as_o our_o panacea_fw-la must_v cure_v or_o else_o it_o will_v not_o be_v a_o panacea_fw-la and_o as_o be_v show_v nothing_o can_v be_v a_o more_o proper_a cure_n of_o grievance_n or_o displeasure_n than_o pleasure_n therefore_o what_o be_v agreeable_a to_o our_o stomach_n and_o consequent_o to_o our_o body_n must_v cure_v not_o cause_n appetite_n as_o meat_n and_o drink_n etc._n etc._n obj._n but_o it_o may_v be_v say_v that_o appetite_n argue_v a_o good_a digestion_n which_o be_v good_a for_o the_o body_n ans._n it_o do_v indeed_o argue_v a_o quick_a digestion_n and_o great_a expense_n of_o the_o recruit_n take_v in_o but_o still_o it_o be_v all_o bottom_v upon_o deficiency_n and_o digestion_n may_v be_v and_o be_v very_o often_o too_o quick_a as_o in_o the_o boulimia_fw-la or_o canine_a appetite_n nature_n delight_v in_o a_o gentle_a kind_a and_o gradual_a dissolution_n of_o the_o meat_n at_o stomach_n to_o which_o you_o will_v find_v by_o and_o by_o that_o opium_n very_o much_o conduce_v by_o its_o resolve_v quality_n 2._o nothing_o in_o nature_n be_v more_o please_v to_o the_o sensitive_a soul_n as_o appear_v by_o the_o whole_a series_n of_o our_o discourse_n and_o the_o explain_v all_o the_o phenomena_n or_o good_a effect_n of_o opium_n by_o that_o very_a pleasure_n of_o the_o sensitive_a soul_n therefore_o 3._o it_o as_o be_v manifest_o show_v do_v thereby_o take_v off_o all_o grievance_n which_o be_v the_o essential_a form_n of_o disease_n and_o the_o essential_a form_n of_o disease_n be_v take_v away_o which_o give_v they_o be_v and_o make_v they_o to_o be_v what_o they_o be_v according_a to_o the_o definition_n of_o a_o essential_a form_n the_o very_a be_v of_o disease_n must_v be_v take_v away_o therefore_o our_o sal-volatile-oleosum_a be_v a_o complete_a panacea_fw-la that_o take_v away_o the_o essence_n or_o be_v of_o disease_n in_o take_v away_o the_o grievance_n thereof_o here_o it_o may_v be_v say_v that_o the_o matter_n of_o the_o distemper_n remain_v and_o consequent_o a_o disposition_n to_o a_o relapse_n as_o soon_o as_o the_o sal-volatile-oleosum_a have_v end_v its_o operation_n but_o what_o need_v it_o end_n at_o all_o if_o you_o please_v it_o may_v be_v renew_v without_o danger_n for_o this_o be_v not_o as_o resinous_a opium_n till_o the_o matter_n be_v subdue_v thereby_o which_o it_o will_v also_o do_v as_o appear_v more_o manifest_o by_o the_o follow_a qualification_n for_o as_o have_v be_v show_v 4._o it_o compose_v comfort_n enlivens_fw-la encourage_v invigorate_n and_o cause_v a_o great_a euphory_n of_o the_o sensitive_a soul_n and_o spirit_n which_o be_v our_o natural_a active_a
proclaim_v their_o ignorance_n and_o glory_v in_o their_o great_a shame_n and_o disgrace_n of_o mankind_n that_o humane_a species_n shall_v have_v any_o such_o unthinking_a brute_n in_o it_o iv_o we_o must_v not_o use_v acid_n in_o the_o preparation_n thereof_o 1._o because_o be_v in_o their_o nature_n opposite_a to_o volatile_a salt_n it_o can_v be_v do_v without_o injury_n to_o the_o sal-volatile-oleosum_a of_o opium_n 2._o because_o they_o can_v so_o well_o agree_v with_o the_o oily_a part_n of_o it_o yet_o be_v they_o not_o so_o much_o to_o be_v blame_v as_o extract_n make_v in_o spirit_n of_o wine_n or_o sulphureous_a menstruum_n because_o acid_a menstruum_n leave_v the_o rosin_n behind_o they_o untouched_a or_o not_o extract_v v._o a_o salino-volatile_a menstruum_fw-la as_o spirit_n of_o sal_fw-la ammoniac_a of_o urine_n etc._n etc._n be_v not_o so_o proper_a 1._o it_o may_v render_v the_o sal-volatile-oleosum_a of_o opium_n too_o acrimonious_a 2._o because_o by_o its_o volatility_n acrimony_n etc._n etc._n it_o may_v cause_v too_o great_a a_o stir_n in_o the_o blood_n etc._n etc._n and_o so_o oppose_v or_o hinder_v sleep_n which_o be_v one_o of_o the_o most_o happy_a and_o useful_a effect_n of_o opium_n or_o it_o be_v sal-volatile-oleosum_a 3._o because_o it_o may_v have_v undue_a effect_n by_o alter_v its_o general_a disposition_n nay_o vi_o we_o be_v not_o to_o use_v a_o lixivial_a menstruum_fw-la though_o so_o much_o cry_v up_o 1._o because_o it_o extract_v the_o resinous_a part_n which_o experto_fw-la crede_fw-la roberto_n i_o have_v find_v to_o be_v pernicious_a upon_o that_o account_n like_o extract_n in_o spirit_n of_o wine_n unless_o great_a care_n be_v take_v to_o separate_v those_o part_n which_o be_v not_o easy_o do_v by_o filtration_n etc._n etc._n 2._o because_o be_v very_o apt_a to_o join_v with_o the_o oily_a part_n and_o quite_o to_o destroy_v their_o nature_n by_o convert_v it_o into_o a_o kind_n of_o sapo_n it_o may_v deal_v so_o with_o some_o of_o the_o oily_a part_n of_o the_o sal-volatile-oleosum_a of_o opium_n 3._o because_o there_o be_v no_o need_n to_o run_v any_o of_o these_o hazard_n since_o the_o sal-volatile-oleosum_a may_v be_v as_o i_o shall_v show_v easy_o extract_v in_o its_o purity_n without_o those_o trouble_n and_o danger_n 4._o because_o any_o tincture_n make_v thus_o be_v apt_a to_o let_v go_v the_o rosin_n at_o stomach_n if_o it_o be_v dilute_v with_o aqueous_a moisture_n take_v before_o with_o it_o or_o after_o it_o which_o so_o be_v let_v go_v coalesces_fw-la and_o do_v mischief_n vii_o the_o use_n of_o fire_n any_o way_n beside_o that_o of_o its_o torrefaction_n be_v much_o to_o be_v suspect_v 1._o because_o the_o sal-volatile-oleosum_a may_v be_v in_o some_o measure_n thereby_o evaporate_v or_o 2._o an_fw-mi empyreum_fw-la contract_v and_o 3._o the_o rosin_n as_o be_v say_v of_o its_o torrefaction_n grow_v the_o more_o in_o proportion_n if_o any_o of_o the_o sal-volatile-oleosum_a or_o but_o the_o phlegm_n be_v by_o that_o mean_n evaporate_v and_o the_o remainder_n keep_v for_o use_v and_o particular_o viii_o the_o distillation_n thereof_o may_v cause_v mighty_a alteration_n in_o its_o property_n strength_n etc._n etc._n we_o must_v therefore_o avoid_v all_o these_o way_n of_o prepare_v it_o and_o yet_o must_v we_o 1._o separate_a the_o sal-volatile-oleosum_a of_o opium_n from_o all_o its_o rosin_n earth_n filth_n and_o dross_n 2._o no_o way_n weaken_v it_o alter_v it_o or_o add_v new_a quality_n thereto_o but_o preserve_v this_o most_o noble_a and_o inestimable_a medicament_n in_o its_o purity_n and_o sincerity_n to_o this_o end_n rain_n water_v distil_v use_v cold_a answer_v all_o intent_n for_o 1._o it_o ready_o imbibe_v the_o sal-volatile-oleosum_a of_o opium_n without_o fire_n heat_v lixivial_a salt_n as_o salt_n of_o tartar_n etc._n etc._n 2._o it_o imbibe_v none_o of_o the_o rosin_n of_o the_o opium_n but_o let_v it_o all_o subside_n together_o with_o the_o earthy_a and_o drossy_a part_n separate_v the_o light_a filth_n if_o there_o be_v any_o to_o the_o surface_n 3._o it_o no_o way_n weaken_v alter_v or_o add_v any_o new_a quality_n to_o the_o sal-volatile-oleosum_a 4._o whatever_o cold_a water_n dissolve_v which_o be_v the_o general_n drink_v or_o menstruum_fw-la appoint_v by_o the_o alwise_a creater_n for_o the_o dissolution_n of_o all_o thing_n take_v into_o the_o stomach_n of_o animal_n be_v easy_o dissolve_v at_o stomach_n by_o its_o more_o powerful_a and_o agreeable_a menstruum_fw-la and_o not_o only_o so_o but_z 5._o water_n itself_o be_v a_o mighty_a stomachick_n and_o causer_n of_o digestion_n as_o hypocrates_n positive_o declare_v l._n 6._o epidem_fw-la sect._n 4._o but_o there_o be_v no_o need_n of_o quote_v hypocrates_n in_o so_o notorious_a a_o thing_n daily_a experience_n tell_v we_o the_o same_o do_v not_o all_o animal_n by_o its_o help_n digest_v their_o food_n do_v not_o all_o mineral_n water_n scarce_o any_o except_v create_v a_o appetite_n and_o cause_n digestion_n even_o when_o no_o such_o effect_n can_v be_v attribute_v to_o the_o mineral_n they_o contain_v than_o which_o they_o do_v also_o as_o may_v be_v very_o easy_o prove_v more_o good_a general_o speak_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d for_o which_o and_o many_o more_o reason_n it_o be_v great_a neglect_n and_o folly_n that_o it_o be_v not_o more_o use_v for_o extract_n etc._n etc._n for_o then_o they_o ready_o dissolve_v at_o stomach_n and_o thereby_o 〈◊〉_d and_o speedy_o take_v effect_n give_v it_o the_o least_o 〈◊〉_d and_o disturbance_n that_o may_v be_v as_o be_v experimental_o find_v in_o that_o of_o aloe_n scammony_n briony_n 〈◊〉_d agariâ—_n 〈◊〉_d coloquintida_n sena_n and_o what_o not_o unless_o the_o virtue_n lie_v in_o the_o resinous_a parâ—s_n for_o then_o sulphureous_a or_o lixivial_a menstruum_n be_v convenient_a how_o inconvenient_a be_v they_o then_o when_o the_o evil_a or_o mischief_n lie_v therein_o as_o in_o our_o case_n 6._o it_o be_v not_o to_o be_v doubt_v but_o water_n general_o imbibe_v what_o be_v best_a and_o most_o agreeable_a to_o our_o body_n it_o be_v the_o general_n menstruum_fw-la appoint_v by_o wisdom_n itself_o for_o that_o use_v and_o to_o be_v the_o vehicle_n of_o what_o be_v best_a in_o all_o our_o food_n etc._n etc._n to_o the_o blood_n however_o there_o can_v be_v no_o doubt_n of_o what_o main_o concern_v we_o at_o present_a its_o most_o ready_a dissolve_v our_o panacea_fw-la in_o the_o stomach_n that_o do_v it_o out_o of_o it_o when_o cold_a without_o the_o convenient_a digestive_a heat_n and_o powerful_a menstruum_fw-la that_o it_o find_v there_o therefore_o take_v of_o distil_a rain-water_n 24_o ounce_n of_o choice_a opium_n slice_v thin_a 8_o ounce_n put_v they_o together_o in_o a_o strong_a glass_n vessel_n of_o bottle-metal_n that_o contain_v about_o 3_o piâ—ts_n let_v it_o be_v of_o a_o tall_a figure_n with_o a_o mouth_n that_o convenient_o receive_v a_o cork_n a_o large_a glass_n bottle_n may_v serve_v the_o turn_n cork_n it_o so_o as_o the_o cork_n may_v be_v easy_o take_v out_o shake_v it_o 3_o or_o 4_o time_n a_o day_n for_o 6_o day_n and_o keep_a it_o in_o a_o place_n free_a from_o frost_n or_o any_o very_a sensible_a degree_n of_o heat_n which_o be_v perform_v lie_v the_o vessel_n side-long_a for_o 24_o hour_n long_o and_o afterward_o decant_v and_o filter_n your_o tincture_n which_o will_v be_v of_o a_o ruby_n colour_n and_o put_v it_o into_o a_o glass_n bottle_n of_o such_o a_o bigness_n as_o that_o it_o may_v fill_v it_o within_o a_o small_a matter_n of_o the_o cork_n and_o so_o let_v it_o stand_v for_o 3_o or_o 4_o day_n then_o poâ—r_v off_o some_o of_o the_o surface_n of_o it_o and_o instead_o thereof_o put_v sweet_a oil_n thereon_o let_v the_o vessel_n have_v a_o convenient_a dust_n or_o pipe_n in_o the_o side_n thereof_o to_o empty_v it_o out_o upon_o occasion_n this_o i_o call_v the_o liquid_a panacea_fw-la of_o opium_n to_o the_o faeces_fw-la add_v a_o pint_n of_o cold_a distil_a water_n shake_v the_o vessel_n as_o before_o 3_o or_o 4_o time_n in_o the_o day_n let_v it_o stand_v on_o it_o 24_o hour_n and_o in_o the_o morning_n decant_v it_o into_o another_o vessel_n repeat_v the_o same_o quantity_n of_o distil_a rain-water_n till_o the_o opium_n no_o long_o tinge_v it_o or_o very_o inconsiderable_o in_o 24_o hour_n at_o last_o you_o may_v use_v water_n keep_v hot_a by_o a_o fire_n &c_n &c_n the_o better_a to_o extract_v the_o remain_v sal-volatile-oleosum_a evaporate_v all_o these_o last_o water_n in_o balneo_fw-la to_o the_o consistence_n of_o a_o extract_n this_o i_o call_v the_o solid_a panacea_fw-la of_o opium_n god_n and_o nature_n act_v by_o simple_a mean_n and_o nothing_o in_o imitation_n of_o they_o be_v more_o commendable_a in_o a_o medicament_n than_o simplicity_n therefore_o i_o shall_v add_v nothing_o to_o the_o panacea_n but_o whole_o
etc._n as_o wine_n hot_a liquor_n and_o opium_n do_v 12._o opium_n do_v very_o much_o open_v the_o pore_n and_o cause_n perspiration_n etc._n etc._n which_o only_a heat_n as_o that_o in_o bath_n bagnio_n hot_a house_n and_o hot_a thing_n do_v but_o cold_a shut_v the_o pore_n as_o all_o know_v therefore_o 13._o opium_n cure_v and_o prevent_v cold_n which_o be_v another_o argument_n of_o its_o heat_n 14._o it_o be_v a_o great_a aphrodisiack_a or_o exciter_n to_o venery_n which_o cold_a thing_n chill_a but_o hot_a thing_n as_o cantharides_n bee_n pismire_n onion_n garlic_n leek_n rocket_n squill_n horse_n radish_n sem._n human._n etc._n etc._n do_v promote_v 15._o nothing_o cause_v indolence_n give_v internal_o but_o wine_n hot_a liquor_n etc._n etc._n as_o i_o can_v think_v of_o and_o opium_n cause_v it_o much_o after_o the_o same_o manner_n as_o wine_n do_v first_o cause_v mirth_n and_o jollity_n and_o upon_o increase_n of_o quantity_n very_o considerable_a indolence_n it_o be_v true_a that_o cold_a will_v external_o cause_v a_o stupor_n if_o it_o be_v intense_a so_o as_o to_o constringe_v the_o part_n and_o exclude_v the_o spirit_n but_o otherwise_o it_o make_v the_o feel_v more_o nice_a as_o all_o know_v by_o experience_n because_o every_o little_a hurt_n affect_v we_o more_o when_o we_o be_v cold_a than_o hot_a but_o this_o be_v not_o the_o case_n of_o relax_a opium_n which_o be_v use_v internal_o to_o take_v away_o pain_n as_o wine_n etc._n etc._n 16._o nothing_o take_v away_o the_o effect_n of_o opium_n or_o drunkeness_n better_o than_o cold_a thing_n internal_o and_o external_o as_o acid_n dip_v in_o cold_a water_n etc._n etc._n 17._o opium_n relax_n all_o part_n which_o heat_n do_v and_o cold_a constringe_n as_o be_v intimate_v 18._o wedelius_n confess_v though_o it_o make_v against_o what_o he_o say_v that_o he_o never_o observe_v a_o soporose_n distemper_n where_o there_o be_v not_o a_o preternatural_a heat_n opiolog_fw-la lib._n 1._o sect._n 1_o cap._n 12._o p._n 46._o 19_o if_o it_o cause_v sleep_n by_o its_o cold_a quality_n than_o all_o thing_n that_o be_v cold_a will_v do_v it_o proportionable_o cucumber_n purslane_n etc._n etc._n will_v be_v so_o great_a hypnotick_n that_o we_o shall_v not_o be_v able_a to_o eat_v a_o drachm_n of_o they_o but_o that_o they_o will_v cause_v a_o great_a sopor_fw-la but_o there_o be_v no_o such_o thing_n and_o hot_a thing_n be_v much_o more_o apt_a to_o cause_v sleep_n or_o a_o sopor_fw-la as_o wine_n hot_a spirit_n onion_n garlic_n and_o such_o like_a 20._o opium_n cause_v a_o redness_n or_o efflorescence_n of_o the_o skin_n make_v it_o sensible_o warm_a as_o heat_n wine_n and_o strong_a liquor_n do_v 21._o it_o cause_v also_o a_o itch_a of_o the_o skin_n which_o only_o hot_a thing_n do_v 22._o half_n a_o drachm_n of_o opium_n in_o clyster_n have_v cause_v a_o violent_a heat_n in_o the_o gut_n 23._o it_o stop_v diarrheas_n or_o looseness_n which_o cold_a cause_n 24._o it_o stop_v defluxion_n cough_n etc._n etc._n which_o cold_a cause_n 25._o to_o pin_v up_o all_o its_o predominant_a principle_n appear_v by_o autopsie_n upon_o its_o chemical_a analysis_n to_o be_v volatile_a salt_n and_o sulphur_n beside_o this_o opinion_n of_o the_o coldness_n of_o opium_n be_v very_o much_o explode_v and_o indeed_o it_o be_v so_o apparent_o false_a and_o absurd_a that_o i_o shall_v not_o have_v think_v it_o worth_a while_n to_o argue_v against_o it_o but_o that_o it_o lay_v so_o in_o my_o way_n that_o regular_o i_o can_v not_o well_o avoid_v it_o without_o breach_n of_o order_n and_o method_n i_o may_v have_v add_v that_o it_o resolve_v attenuate_v etc._n etc._n but_o it_o be_v needless_a to_o say_v any_o more_o it_o be_v very_o false_a and_o erroneous_a that_o it_o stop_v flux_n by_o incrassate_v and_o bind_v which_o be_v account_v cold_a quality_n if_o so_o how_o shall_v it_o stop_v they_o when_o pound_n of_o incrassative_n and_o binder_n have_v fail_v though_o the_o opium_n be_v give_v only_o in_o the_o quantity_n of_o a_o grain_n or_o two_o how_o shall_v it_o stop_v or_o moderate_a flux_n even_o while_o it_o be_v yet_o at_o stomach_n as_o it_o most_o certain_o do_v it_o bear_v as_o etmuller_n well_o observe_v no_o proportion_n to_o the_o blood_n and_o humour_n to_o have_v any_o effect_n that_o may_v be_v remarkable_a upon_o they_o for_o a_o grain_n be_v but_o as_o 1_o to_o 115200_o to_o the_o blood_n of_o he_o that_o have_v 20_o pound_n of_o blood_n which_o a_o ordinary_a man_n have_v beside_o how_o can_v altenuative_n resolver_n and_o discusser_n incrassate_fw-it or_o bind_z but_o more_o especial_o how_o can_v so_o great_a a_o relaxer_n of_o part_n be_v a_o constringer_n thereof_o that_o be_v perfect_a contradiction_n and_o how_o can_v a_o mere_a sal_fw-la volatile_a oleosum_fw-la in_o which_o all_o its_o virtue_n lie_v as_o will_v plain_o appear_v thicken_v and_o bind_v the_o truth_n be_v that_o it_o stop_v flux_n as_o sleep_n do_v by_o take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o solicit_v the_o part_n to_o contract_n and_o so_o to_o extrude_v and_o squeeze_v they_o out_o it_o promote_v perspiration_n by_o relax_v the_o pore_n as_o sleep_n do_v it_o also_o seem_v to_o thicken_v rheum_n as_o sleep_n do_v because_o it_o cause_v sleep_n or_o at_o least_o take_v away_o a_o sense_n of_o the_o irritation_n of_o the_o rheum_n be_v thereby_o suffer_v to_o stay_v till_o it_o thicken_v by_o the_o heat_n of_o the_o body_n the_o irritation_n also_o at_o windpipe_n be_v less_o because_o the_o flux_n of_o the_o rheum_n be_v moderate_v for_o the_o reason_n aforesaid_a but_o of_o these_o thing_n more_o full_o when_o we_o come_v to_o explain_v the_o cause_n or_o cause_n of_o the_o effect_n of_o opium_n chap._n x._o it_o be_v prove_v that_o opium_n send_v no_o fume_n etc._n etc._n from_o the_o stomach_n to_o the_o head_n brain_n etc._n etc._n and_o therefore_o that_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n etc._n etc._n by_o that_o mean_n though_o the_o opinion_n of_o the_o cold_a of_o opium_n be_v much_o explode_v that_o of_o fume_n vapour_n or_o aura_n arise_v from_o the_o opium_n at_o stomach_n and_o mount_v up_o to_o the_o brain_n etc._n etc._n be_v as_o much_o receive_v and_o embrace_v i_o know_v none_o but_o such_o as_o think_v it_o absolute_o necessary_a consider_v that_o it_o be_v most_o certain_a and_o allow_v by_o all_o observe_a man_n that_o opium_n produce_v all_o or_o most_o of_o its_o effect_n while_o it_o be_v at_o stomach_n that_o the_o genus_fw-la neruâ—sum_fw-la be_v most_o concern_v in_o its_o operation_n and_o that_o as_o be_v say_v there_o be_v no_o operation_n or_o action_n but_o by_o contact_n so_o that_o the_o modern_n acquiesce_v in_o the_o necessity_n of_o its_o operate_n that_o way_n because_o they_o can_v conceive_v no_o other_o which_o be_v no_o proof_n but_o a_o defect_n of_o their_o conception_n look_v upon_o it_o as_o invincible_a and_o uncontrollable_a evidence_n oâ—_n its_o operate_n by_o detachment_n of_o fume_n or_o 〈◊〉_d send_v up_o to_o the_o brain_n from_o the_o stomach_n which_o appear_v so_o undeniable_o conclusive_a that_o neither_o the_o want_n of_o a_o sensible_a passage_n nor_o any_o other_o inconvenience_n signify_v any_o thing_n with_o they_o to_o the_o contrary_a therefore_o it_o become_v a_o establish_a foundation_n by_o common_a consent_n only_o they_o differ_v as_o be_v show_v in_o the_o manner_n how_o those_o fume_n produce_v the_o effect_n of_o opium_n and_o well_o they_o may_v see_v there_o be_v no_o such_o thing_n nor_o possibility_n if_o they_o be_v of_o ever_o explicate_v the_o various_a effect_n of_o opium_n by_o that_o mean_n as_o will_v manifest_o appear_v i_o confess_v that_o if_o opium_n operate_v by_o such_o fume_n pass_v from_o the_o stomach_n to_o the_o brain_n etc._n etc._n it_o will_v be_v easy_a to_o conceive_v how_o it_o shall_v diminish_v or_o disable_v nay_o utter_o ruin_v the_o animal_n spirit_n and_o indeed_o impossible_a rational_o to_o conceive_v how_o they_o can_v do_v otherwise_o but_o then_o the_o enliven_a invigorate_n and_o encourage_v effect_n of_o opium_n which_o be_v its_o constant_a and_o most_o genuine_a off_o spring_n will_v lie_v upon_o our_o hand_n without_o any_o possibility_n of_o give_v a_o account_n thereof_o for_o certain_o dull_a heavy_a unnatural_a undigested_a and_o cloudy_a fume_n or_o vapour_n can_v not_o advantage_v the_o animal_n spirit_n cause_v a_o triumph_n or_o ovation_n thereof_o at_o their_o access_n courage_n serenity_n promptitude_n magnanimity_n euphory_n inclination_n to_o venery_n etc._n etc._n which_o we_o be_v most_o oblige_v to_o regard_n as_o be_v its_o most_o natural_a and_o proper_a effect_n this_o opinion_n of_o the_o modern_n do_v presume_v or_o suppose_v for_o they_o prove_v nothing_o first_o that_o fume_n
or_o vapour_n do_v ready_o and_o free_o pass_v from_o the_o stomach_n to_o the_o brain_n because_o the_o gross_a fume_n as_o they_o call_v they_o of_o a_o grain_n or_o two_o of_o opium_n always_o operate_v before_o it_o be_v out_o of_o the_o stomach_n but_o they_o never_o see_v such_o fume_n pass_v nor_o their_o passage_n only_o suppose_v both_o and_o that_o mere_o upon_o a_o imagination_n that_o it_o must_v be_v so_o because_o they_o forsooth_o can_v conceive_v any_o other_o way_n by_o which_o opium_n can_v affect_v the_o head_n nerve_n etc._n etc._n while_o it_o be_v at_o stomach_n whereas_o i_o can_v and_o shall_v god_n will_v show_v they_o another_o mean_n or_o way_n to_o do_v it_o that_o be_v sensible_a and_o not_o whole_o precarious_a as_o they_o be_v and_o that_o in_o the_o mean_a manner_n because_o all_o their_o ground_n to_o suppose_v it_o be_v their_o inability_n to_o conceive_v or_o apprehend_v what_o be_v as_o i_o shall_v show_v very_o sensible_a nay_o obvious_a also_o second_o they_o suppose_v that_o such_o fume_n will_v serve_v to_o solve_v all_o the_o phoenomena_n and_o operation_n of_o opium_n whereas_o it_o be_v utter_o impossible_a they_o shall_v solve_v the_o enliven_a and_o invigorate_n effect_n thereof_o as_o have_v be_v show_v and_o shall_v be_v further_o prove_v if_o god_n permit_v it_o be_v easy_a to_o evidence_n but_o that_o it_o will_v be_v tedious_a and_o needless_a for_o their_o incompetency_n to_o solve_v the_o most_o proper_a effect_n of_o opium_n be_v more_o than_o enough_o that_o such_o fume_n or_o vapour_n can_v true_o solve_v no_o effect_n of_o opium_n unless_o it_o be_v that_o of_o death_n or_o some_o deadly_a symptom_n nay_o they_o will_v not_o solve_v the_o most_o likely_a to_o be_v cause_v by_o vapour_n viz._n sleep_v which_o all_o man_n as_o wedelius_n say_v allow_v to_o be_v the_o effect_n of_o fume_n or_o vapour_n in_o his_o opiologia_fw-la c._n 11._o p._n 35._o somnum_fw-la naturalem_fw-la say_v he_o omnes_fw-la concedunt_fw-la producere_fw-la suaviores_fw-la &_o blandas_fw-la 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d seu_fw-la vapores_fw-la primum_fw-la 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d demulcentes_fw-la qui_fw-la cum_fw-la spiritibus_fw-la animalibus_fw-la mixti_fw-la torpidos_fw-la quasi_fw-la illos_fw-la reddunt_fw-la that_o be_v all_o grant_v that_o kind_n and_o gentle_a fume_n do_v cause_n natural_a sleep_n etc._n etc._n which_o be_v most_o certain_o false_a though_o i_o very_o much_o doubt_n that_o this_o groundless_a presumption_n which_o as_o he_o intimate_v all_o embrace_n have_v be_v a_o great_a cause_n of_o this_o airy_a imagination_n of_o fume_n in_o the_o case_n of_o opium_n because_o man_n look_v upon_o sleep_n agree_v upon_o to_o be_v cause_v by_o fume_n to_o be_v the_o prime_n lead_v and_o most_o proper_a effect_n of_o opium_n which_o be_v also_o false_a it_o be_v but_o a_o mere_a accident_n as_o have_v be_v show_v and_o when_o it_o happen_v general_o require_v lie_v or_o sit_v still_o to_o assist_v it_o whereas_o the_o watch_a that_o be_v the_o effect_n of_o opium_n require_v no_o help_n and_o can_v be_v put_v off_o as_o sleep_n can_v by_o motion_n action_n etc._n etc._n notwithstanding_o all_o endeavour_n to_o the_o contrary_n now_o i_o will_v know_v of_o any_o man_n which_o be_v the_o most_o proper_a and_o natural_a effect_n of_o any_o cause_n that_o which_o nothing_o can_v hinder_v or_o that_o which_o every_o action_n can_v but_o i_o run_v too_o far_o upon_o this_o matter_n which_o belong_v more_o apt_o to_o that_o part_n of_o this_o book_n that_o explain_v all_o the_o effect_n of_o opium_n and_o so_o must_v return_v to_o that_o of_o fume_n which_o do_v not_o cause_v natural_a sleep_n as_o manifest_o appear_v 1._o because_o that_o which_o cause_v natural_a sleep_n must_v in_o all_o reason_n as_o it_o be_v always_o in_o the_o wise_a work_n of_o nature_n bear_v a_o proportion_n thereto_o but_o fume_n suppose_v their_o be_v bear_v no_o proportion_n to_o our_o sleep_n certain_o a_o work_a labourer_n that_o toil_v all_o the_o day_n must_v spend_v the_o fume_n of_o his_o body_n in_o the_o high_a degree_n and_o feed_v upon_o dry_a bread_n and_o cheese_n must_v breed_v few_o fume_n yet_o none_o sleep_v better_a or_o sweet_a than_o he_o the_o like_a be_v to_o be_v say_v of_o a_o travel_a man_n a_o tire_a person_n etc._n etc._n who_o often_o fall_v asleep_a before_o they_o eat_v or_o drink_v to_o renew_v their_o fume_n which_o they_o have_v spend_v in_o a_o extraordinary_a manner_n why_o sleep_n that_o be_v design_v for_o refreshment_n and_o recruit_v shall_v depend_v upon_o fume_n no_o man_n can_v tell_v for_o than_o our_o refreshment_n will_v whole_o depend_v thereon_o and_o no_o man_n have_v any_o recruit_v by_o sleep_n but_o in_o proportion_n thereunto_o who_o dare_v accuse_v our_o wise_a and_o good_a maker_n of_o such_o contrivance_n who_o in_o nature_n always_o proportion_n thing_n to_o the_o exigency_n thereof_o and_o therefore_o sleep_v not_o to_o fume_n but_o to_o that_o which_o be_v impair_v in_o we_o for_o want_v thereof_o which_o be_v always_o contrive_v by_o wise_a nature_n if_o you_o will_v observe_v it_o to_o be_v the_o prompt_a cause_n to_o the_o recruit_v and_o then_o proportion_n be_v due_o observe_v because_o we_o be_v prompt_v exact_o according_a to_o the_o exigence_n or_o necessity_n of_o nature_n as_o become_v the_o wisdom_n of_o our_o creator_n and_o preserver_n this_o rule_n if_o due_o attend_v to_o will_v easy_o speedy_o and_o certain_o lead_v you_o to_o the_o knowledge_n of_o the_o true_a natural_a cause_n of_o hunger_n thirst_v inclination_n to_o sleep_n and_o all_o such_o call_v for_o restauration_n all_o which_o i_o can_v soon_o satisfy_v you_o in_o but_o that_o it_o be_v not_o my_o business_n at_o present_a and_o that_o it_o will_v too_o much_o anticipate_v my_o design_a tract_n of_o animal_n mechanism_n nor_o do_v labour_v itself_o bear_v any_o exact_a proportion_n thereunto_o because_o many_o healthy_a people_n that_o be_v idle_a all_o day_n sleep_v long_o sound_o and_o sweet_o every_o night_n as_o well_o as_o labourer_n so_o that_o in_o short_a it_o must_v be_v somewhat_o that_o belong_v to_o watch_v as_o such_o for_o sleep_v general_o bear_v the_o best_a proportion_n to_o watch_v if_o we_o watch_v much_o or_o little_a our_o sleep_n bear_v some_o proportion_n thereto_o though_o there_o may_v be_v in_o this_o as_o well_o as_o in_o hunger_n thirst_v etc._n etc._n accident_n that_o cause_n the_o promptitude_n to_o be_v more_o or_o less_o and_o so_o vary_v the_o true_a natural_a proportion_n all_o which_o have_v the_o nature_n of_o disease_n as_o canine_a appetite_n coma_n caros_n preternatural_a thrists_z etc._n etc._n what_o it_o be_v that_o watch_a cause_n to_o prompt_v we_o to_o sleep_n must_v be_v some_o impair_v make_v thereby_o as_o such_o and_o not_o the_o foolish_a conceit_n of_o fume_n and_o it_o be_v easy_a for_o i_o to_o illustrate_v what_o it_o be_v but_o that_o it_o will_v require_v some_o sheet_n of_o paper_n and_o as_o i_o say_v before_o anticipate_v my_o discourse_n of_o animal_n mechanism_n which_o i_o hope_v to_o have_v publish_v before_o this_o book_n and_o will_v have_v be_v most_o convenient_a because_o the_o principle_n therein_o state_v may_v serve_v to_o explain_v the_o effect_n of_o opium_n but_o that_o the_o want_n of_o a_o few_o experiment_n have_v to_o my_o grief_n hitherto_o delay_v it_o and_o therefore_o i_o must_v be_v put_v to_o much_o trouble_v in_o this_o work_n for_o want_v thereof_o because_o i_o be_o resolve_v not_o to_o spare_v myself_o in_o order_n to_o satisfy_v the_o reader_n in_o this_o great_a and_o unexplicate_v mystery_n 2._o if_o vapour_n be_v the_o cause_n of_o natural_a sleep_n it_o be_v impossible_a that_o the_o prick_n of_o a_o pin_n or_o a_o sharp_a sound_n etc._n etc._n shall_v awake_v one_o ten_o or_o twenty_o time_n in_o a_o hour_n for_o either_o the_o prick_n must_v in_o a_o instant_n discuss_v all_o the_o fume_n in_o be_v which_o be_v impossible_a to_o be_v imagine_v and_o they_o as_o often_o return_v to_o cause_n sleep_v again_o or_o intercept_v their_o motion_n from_o the_o stomach_n to_o the_o head_n which_o no_o man_n can_v have_v any_o conception_n of_o the_o efficacy_n of_o the_o pin_n or_o sound_v so_o to_o do_v or_o they_o must_v both_o discuss_v and_o intercept_v the_o fume_n which_o indeed_o if_o the_o case_n be_v such_o will_v be_v necessary_a to_o make_v a_o clear_a awake_v which_o be_v yet_o far_o more_o unconceivable_a what_o paltry_a trifle_n do_v the_o world_n embrace_v instead_o of_o truth_n and_o reason_n 3._o several_a person_n whereof_o i_o be_o one_o do_v awake_a in_o a_o minute_n or_o two_o after_o they_o first_o fall_v asleep_a in_o bed_n at_o night_n which_o will_v be_v absolute_o impossible_a if_o fume_n cause_v sleep_n for_o the_o fume_n will_v
as_o to_o the_o nose_n and_o eye_n for_o though_o some_o of_o my_o reader_n may_v not_o easy_o conceive_v it_o the_o representation_n of_o thing_n may_v have_v be_v convey_v by_o reflection_n and_o refraction_n of_o light_n without_o exclude_v the_o air_n but_o that_o it_o be_v more_o convenient_a and_o safe_a for_o the_o brain_n and_o optic_a nerve_n which_o be_v much_o the_o same_o matter_n with_o the_o brain_n and_o a_o production_n thereof_o that_o the_o air_n shall_v be_v exclude_v 6._o notwithstanding_o all_o this_o care_n to_o exclude_v extraneous_a particle_n how_o fine_a soever_o we_o do_v find_v that_o those_o very_a impulse_n convey_v by_o the_o animal_n spirit_n themselves_o in_o the_o most_o gentle_a manner_n imaginable_a do_v often_o offend_v the_o brain_n now_o fair_o consider_v the_o great_a excellency_n and_o use_v of_o the_o brain_n viz._n to_o separate_v the_o animal_n spirit_n to_o accommodate_v the_o soul_n with_o a_o fit_a seat_n for_o it_o its_o tenderness_n and_o softness_n to_o be_v next_o to_o liquidity_n how_o careful_o it_o be_v guard_v with_o about_o nine_o or_o ten_o circumvallation_n or_o considerable_a integument_n that_o those_o we_o common_o call_v organ_n of_o sensation_n be_v contrive_v for_o shutter_n out_o or_o excluder_n of_o the_o least_o extraneous_a particle_n effluvia_n or_o aura_n that_o the_o least_o fume_v that_o rise_v from_o any_o part_n and_o arrive_v at_o the_o brain_n cause_v such_o terrible_a and_o dismal_a effect_n and_o that_o most_o gentle_a touch_n of_o the_o animal_n spirit_n do_v offend_v it_o so_o as_o to_o cause_v tragical_a event_n as_o hysterick_a fit_n vertigo_n &c._n &c._n be_v it_o likely_a that_o notwithstanding_o the_o considerableness_n tenderness_n use_v and_o excellency_n of_o the_o brain_n the_o extraordinary_a providence_n use_v in_o guard_v it_o from_o effluvia_n or_o extraneous_a particle_n how_o fine_a soever_o and_o the_o apparent_a mischief_n that_o the_o least_o fume_v nay_o bare_a impulse_n present_v by_o the_o animal_n spirit_n do_v cause_n that_o the_o same_o providence_n that_o so_o guard_v it_o which_o do_v nothing_o in_o vain_a shall_v after_o all_o its_o care_n and_o nice_a circumspection_n to_o exclude_v the_o least_o fume_v etc._n etc._n permit_v and_o free_o let_v loose_v upon_o it_o and_o into_o it_o whole_a and_o even_o continual_a gust_n blast_n and_o vulcano_n of_o acid_n acrimonious_a putrid_a hot_a stink_a corrosive_a fume_n vapour_n and_o steam_n arise_v from_o glut_a debauch_a and_o surfeit_v stomach_n contain_v all_o imaginable_a trash_n hodgepodge_n vermine_n choler_n etc._n etc._n sure_a it_o be_v much_o fit_a quite_o to_o discharge_v and_o rid_v nature_n of_o they_o at_o mouth_n or_o rather_o send_v they_o downward_o with_o their_o fit_a companion_n the_o stink_a ordure_n and_o excrement_n than_o prefer_v they_o to_o the_o high_a and_o noble_a part_n of_o the_o animal_n and_o sacred_a mansion_n of_o the_o soul_n for_o if_o there_o be_v so_o ready_a free_a open_a and_o constant_a a_o passage_n sensible_a or_o insensible_a for_o the_o fume_n of_o opium_n which_o never_o fail_v of_o its_o effect_n then_o certain_o must_v the_o passage_n be_v alike_o free_a to_o all_o other_o fume_n from_o the_o stomach_n see_v they_o be_v so_o to_o those_o gross_a venomous_a and_o pernicious_a fume_n of_o opium_n as_o willis_n and_o most_o of_o the_o modern_a and_o ancient_a physician_n do_v state_n they_o to_o be_v then_o farewell_n soul_n brain_n life_n and_o all_o for_o it_o be_v not_o conceivable_a that_o the_o man_n can_v hold_v out_o one_o houâ—_n under_o such_o horrid_a and_o dismal_a circumstance_n and_o dreadful_a eructation_n of_o rude_a and_o crude_a fume_n who_o can_v not_o bear_v the_o arrival_n of_o the_o least_o vapour_n scarce_o sensible_a in_o quantity_n or_o quality_n arise_v from_o any_o other_o part_n or_o be_v it_o a_o peculiar_a privilege_n that_o the_o stomach_n have_v thus_o to_o send_v fart_n with_o their_o heel_n upward_o as_o belch_a be_v call_v without_o any_o offence_n to_o perfume_v the_o soul_n presence-chamber_n save_v your_o presence_n however_o foh_o for_o shame_n what_o sort_n of_o opinion_n be_v these_o what_o thick_a stink_a and_o dark_a cloud_n scotomy_n and_o stupor_n must_v the_o opiniator_n be_v under_o by_o their_o own_o consent_n 7._o if_o this_o be_v the_o case_n no_o part_n in_o the_o whole_a body_n will_v be_v in_o such_o a_o miserable_a state_n as_o the_o chief_a for_o the_o rectum_fw-la or_o colon_n be_v fit_v and_o fortify_v by_o nature_n to_o bear_v such_o thing_n so_o be_v not_o the_o tender_a brain_n 8._o what_o horse_n brain_n much_o less_o humane_a one_o can_v bear_v incessant_a raking_n penetration_n stuff_n of_o such_o unnatural_a indigested_a heterogeneous_a rugged_a acid_a acrimonious_a putrid_a and_o impetuous_a fume_n if_o gutta_n cavat_fw-la lapidem_fw-la non_fw-la vi_fw-la sed_fw-la saepe_fw-la cadendo_fw-la what_o will_v become_v of_o the_o tender_a brain_n thus_o â—udely_o rub_v and_o grate_v all_o the_o day_n of_o our_o life_n if_o it_o can_v hold_v out_o any_o for_o it_o be_v incredible_a it_o shall_v 9_o how_o will_v the_o pore_n of_o that_o soft_a substance_n which_o have_v no_o less_o office_n as_o it_o be_v universal_o receive_v than_o to_o separate_v animal_n spirit_n which_o be_v or_o shall_v be_v the_o fine_a and_o most_o subtle_a tenuious_a and_o principal_a thing_n in_o a_o animal_n next_o the_o soul_n itself_o be_v discompose_v tear_v dilate_a stuff_v what_o a_o bless_a sâ—retion_n of_o animal_n spirit_n if_o any_o will_v there_o be_v 10._o it_o be_v observe_v by_o all_o that_o the_o brain_n though_o very_o soft_a receive_v the_o least_o change_n of_o any_o part_n of_o the_o body_n which_o can_v never_o be_v consider_v its_o tenderness_n if_o it_o be_v so_o rake_v by_o all_o sort_n of_o fume_n for_o then_o doubtless_o such_o a_o body_n will_v be_v most_o change_v of_o any_o in_o colour_n substance_n texture_n bigness_n etc._n etc._n what_o will_v become_v of_o memory_n and_o indeed_o of_o all_o the_o faculty_n of_o the_o brain_n can_v a_o soft_a yield_a substance_n continual_o discompose_v preserve_v impression_n make_v thereon_o if_o fume_n flow_v continual_o through_o the_o brain_n they_o must_v wear_v out_o all_o impression_n yea_o and_o the_o brain_n itself_o in_o a_o short_a time_n 11._o it_o will_v be_v very_o dangerous_a to_o eat_v or_o drink_v if_o the_o brain_n must_v suffer_v so_o much_o by_o the_o fume_n of_o meat_n wine_n etc._n etc._n it_o will_v be_v hard_a to_o know_v whether_o it_o be_v best_a to_o eat_v or_o not_o for_o both_o must_v be_v fatal_a 12._o what_o a_o vast_a difference_n shall_v we_o observe_v as_o to_o serenity_n of_o mind_n etc._n etc._n when_o empty_a and_o full_a for_o in_o this_o last_o case_n the_o brain_n must_v be_v all_o in_o a_o cloud_n or_o a_o cloud_n in_o it_o or_o both_o yet_o be_v man_n much_o more_o serenâ—_n prompt_v and_o fit_a for_o any_o thing_n after_o some_o glass_n of_o wine_n than_o before_o and_o after_o moderate_a eat_v than_o when_o hungry_a which_o make_v they_o faint_a peevish_a ill-humoured_a and_o listless_a 13._o if_o the_o vapour_n or_o fume_n of_o opium_n fly_v up_o to_o the_o brain_n cause_v all_o its_o effect_n it_o be_v very_o strange_a that_o our_o fumi_fw-la venduli_fw-la have_v not_o long_o since_o find_v out_o the_o mountebank_n gambol_n of_o stand_v upon_o their_o head_n to_o prevent_v all_o mischief_n from_o opium_n take_v in_o a_o great_a do_v for_o fume_n in_o a_o warm_a live_a body_n will_v not_o descend_v into_o the_o head_n i_o wonder_v they_o do_v not_o find_v out_o such_o a_o easy_a and_o natural_a consequence_n of_o their_o hypothesis_n if_o true_a they_o may_v then_o have_v bold_o mount_v any_o stage_n free_o take_v opium_n in_o the_o sight_n of_o the_o admire_a rabble_n their_o summerset_n go_v upon_o their_o hand_n etc._n etc._n will_v have_v secure_v they_o and_o turn_v danger_n topsie-turvy_o by_o the_o help_n of_o a_o comical_a gesture_n this_o be_v indeed_o somewhat_o to_o purpose_n if_o it_o succeed_v if_o not_o i_o shall_v think_v it_o be_v enough_o to_o ridicule_n their_o hypothesis_n out_o of_o all_o credit_n without_o any_o far_a argument_n i_o dare_v join_v issue_n with_o they_o upon_o that_o point_n that_o it_o will_v not_o succeed_v though_o a_o necessary_a consequence_n of_o their_o opinion_n if_o true_a wherein_o they_o will_v have_v this_o advantage_n that_o they_o will_v confess_v with_o one_o that_o never_o do_v or_o will_v try_v it_o as_o be_v well_o assure_v of_o the_o falsity_n of_o both_o the_o hypothesis_n and_o the_o experiment_n without_o such_o a_o trial_n of_o skill_n now_o i_o think_v that_o i_o have_v say_v enough_o and_o will_v willing_o give_v over_o argue_v and_o spend_v any_o more_o time_n to_o confute_v a_o hypothesis_n so_o absurd_a that_o it_o must_v needs_o appear_v so_o to_o
the_o spirit_n by_o any_o mean_n for_o there_o be_v nothing_o so_o good_a in_o nature_n but_o will_v do_v it_o if_o use_v undue_o or_o immoderate_o as_o wine_n bread_n milk_n honey_n sugar_n beer_n etc._n etc._n in_o excess_n for_o i_o intend_v that_o it_o do_v not_o do_v it_o when_o due_o and_o moderate_o use_v 1._o that_o which_o refresh_v the_o weary_a and_o high_o prevent_v weariness_n must_v add_v to_o or_o excite_v the_o spirit_n which_o be_v direct_o contrary_a to_o diminish_v or_o disable_n they_o but_o opium_n do_v in_o a_o most_o eminent_a manner_n refresh_v the_o weary_v and_o prevent_v weariness_n therefore_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n some_o have_v be_v so_o silly_a and_o inadvertent_n as_o to_o object_n that_o it_o refresh_v the_o weary_a only_o by_o sleep_n it_o be_v matter_n of_o fact_n that_o it_o refresh_v they_o whether_o they_o sleep_v or_o no_o and_o that_o without_o fail_v as_o often_o as_o it_o be_v use_v in_o that_o case_n other_o that_o be_v no_o wise_a have_v say_v that_o it_o only_o take_v off_o the_o sense_n of_o weariness_n by_o stupify_a which_o happen_v by_o the_o diminish_n or_o disable_n of_o the_o animal_n spirit_n bare_a insensibleness_n can_v enable_v the_o spirit_n to_o labour_n with_o eminent_a briskness_n and_o alacrity_n as_o man_n most_o certain_o do_v after_o opium_n be_v take_v be_v fine_o enliven_v and_o invigorate_v as_o with_o generous_a wine_n if_o they_o do_v not_o know_v this_o to_o be_v true_a let_v they_o for_o shame_n hold_v their_o tongue_n till_o they_o know_v matter_n of_o fact_n which_o if_o they_o will_v not_o they_o proclaim_v themselves_o to_o be_v idle_a and_o impertinent_a babbler_n but_o if_o they_o will_v patient_o and_o wise_o abstain_v argue_v till_o they_o be_v satisfy_v as_o to_o matter_n of_o fact_n then_o will_v they_o be_v past_a opinion_n and_o hypothesis_n in_o that_o case_n for_o they_o will_v have_v sensible_a and_o certain_a knowledge_n of_o the_o contrary_a and_o the_o truth_n of_o what_o i_o say_v which_o will_v end_v all_o controversy_n and_o precarious_a squabble_n upon_o false_a supposition_n as_o the_o manner_n be_v that_o can_v lead_v they_o to_o what_o be_v right_o but_o by_o mere_a chance_n and_o never_o to_o a_o true_a knowledge_n that_o they_o be_v in_o the_o right_n which_o make_v it_o none_o in_o effect_n for_o they_o can_v do_v nothing_o with_o assurance_n but_o only_o suppose_v and_o hope_v they_o be_v in_o the_o right_n when_o they_o be_v as_o much_o out_o to_o their_o patient_n sorrow_n as_o physician_n have_v be_v in_o the_o cold_a quality_n and_o fume_n of_o opium_n it_o be_v true_a that_o a_o grain_n or_o two_o of_o opium_n will_n if_o a_o man_n compose_v himself_o sit_v or_o lie_v still_o cause_n a_o sleepiness_n equal_a to_o that_o cause_v by_o spend_v the_o spirit_n by_o a_o day_n be_v labour_n but_o spend_v of_o the_o spirit_n be_v not_o the_o only_a no_o nor_o best_a proportion_v or_o more_o adequate_a cause_n thereof_o as_o i_o have_v show_v if_o loss_n of_o spirit_n be_v the_o adequate_a cause_n of_o sleep_n how_o shall_v good_a and_o generous_a wine_n cause_n sleepiness_n after_o that_o eminent_a rate_n as_o it_o do_v in_o most_o people_n how_o shall_v the_o most_o please_a music_n incline_v such_o as_o lie_v or_o sit_v still_o to_o sleep_v but_o if_o one_o dance_n thereto_o it_o make_v he_o more_o lively_a and_o brisk_a than_o ordinary_a the_o like_a exact_o do_v wine_n and_o opium_n if_o man_n lie_v or_o sit_v still_o but_o otherwise_o they_o make_v they_o much_o more_o brisk_a and_o lively_a and_o able_a to_o undergo_v labour_n action_n etc._n etc._n which_o note_n that_o you_o may_v not_o any_o more_o wonder_n that_o enlivener_n and_o exciter_n of_o the_o spirit_n do_v cause_n sleep_v as_o well_o as_o diminisher_n thereof_o and_o observe_v that_o they_o be_v all_o please_a thing_n as_o music_n wine_n and_o opium_n which_o cause_n pleasant_a dream_n pleasant_a watch_n pleasant_a humour_n etc._n etc._n expect_v more_o of_o this_o matter_n in_o the_o follow_a chapter_n and_o all_o by_o degree_n according_a as_o i_o judge_v the_o prejudice_v world_n will_v bear_v thing_n for_o a_o great_a paradox_n how_o true_a soever_o must_v not_o be_v abrupt_o obtrude_v but_o gentle_o and_o gradual_o usher_v in_o by_o insinuate_v reason_v otherwise_o it_o will_v be_v entertain_v like_o a_o rude_a stranger_n that_o contradict_v a_o multitude_n in_o fashion_n and_o custom_n that_o they_o have_v always_o use_v and_o judge_v to_o be_v the_o very_o best_o however_o unblamable_a consider_v that_o if_o opium_n diminish_v or_o disable_v the_o spirit_n proportionable_a to_o the_o sleepiness_n that_o it_o cause_n as_o a_o hard_a day_n be_v labour_n do_v then_o if_o opium_n be_v give_v a_o man_n after_o a_o hard_a day_n be_v labour_n it_o will_v be_v as_o it_o be_v add_v another_o hard_a day_n be_v labour_v to_o cure_v it_o the_o day_n be_v labour_n and_o opium_n impair_n the_o spirit_n alike_o think_v what_o a_o miserable_a condition_n the_o poor_a man_n will_v be_v in_o especial_o if_o sleep_n do_v not_o make_v he_o some_o amends_o it_o will_v be_v such_o as_o be_v utter_o intolerable_a but_o so_o far_o be_v opium_n from_o any_o such_o effect_n that_o it_o refresh_v he_o though_o he_o sleep_v not_o at_o all_o after_o the_o hard_a day_n be_v labour_n and_o not_o only_o so_o but_o will_v enable_v he_o to_o work_v all_o the_o follow_a night_n with_o great_a alacrity_n if_o need_n require_v it_o what_o a_o condition_n will_v those_o be_v in_o who_o take_v a_o drachm_n of_o it_o twice_o a_o day_n for_o 10_o 20_o or_o 30_o year_n nay_o how_o can_v any_o possible_o do_v it_o for_o half_a 10_o day_n if_o a_o grain_n or_o two_o destroy_v the_o spirit_n so_o much_o as_o to_o cause_v sleepiness_n thereby_o as_o hard_a labour_n do_v which_o they_o must_v allow_v that_o assert_v it_o cause_n sleep_v by_o diminish_v or_o disable_n the_o spirit_n but_o some_o may_v say_v though_o very_o inconsiderate_o that_o it_o only_o disable_v they_o for_o the_o time_n of_o its_o operation_n that_o be_v strange_a indeed_o consider_v that_o even_o during_o that_o time_n they_o be_v most_o enable_v to_o work_n or_o labour_n though_o tire_v before_o and_o that_o it_o 2._o cause_n comfort_n refreshment_n ovation_n of_o the_o spirit_n all_o the_o time_n of_o its_o operation_n as_o wine_n moderate_o take_v do_v especial_o if_o people_n keep_v themselves_o in_o action_n labour_n etc._n etc._n otherwise_o indeed_o they_o may_v fall_v asleep_a upon_o the_o comfortable_a satisfaction_n contentation_n of_o mind_n and_o acquiescence_n of_o spirit_n that_o it_o occasion_n as_o wine_n do_v 3._o the_o first_o effect_n that_o we_o find_v of_o opium_n which_o may_v therefore_o probable_o be_v a_o very_a lead_n fundamental_a and_o significant_a effect_n be_v that_o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o incline_v he_o to_o sleep_n if_o not_o it_o make_v he_o gay_a good_a humour_a brave_a etc._n etc._n it_o be_v a_o pleasure_n so_o sweet_a and_o delicious_a that_o though_o i_o endeavour_v to_o express_v it_o by_o the_o ovation_n of_o the_o spirit_n upon_o joy_n a_o good_a genius_n inform_v a_o man_n or_o the_o helmâ—sians_n archaeus_n in_o his_o best_a humour_n or_o a_o continual_a vâ—real_a pleasure_n wine_n drink_v ad_fw-la hilaritatem_fw-la etc._n etc._n yet_o i_o doubt_v all_o my_o way_n of_o express_v it_o do_v come_v short_a of_o the_o charm_a complacency_n that_o it_o cause_n therefore_o if_o wine_n music_n a_o good_a meal_n agreeable_a frication_n of_o the_o head_n or_o back_o the_o sound_n of_o water_n etc._n etc._n do_v incline_v we_o to_o sleep_v by_o the_o pleasure_n thereof_o which_o lull_v and_o soothe_v we_o to_o it_o as_o be_v most_o certain_a if_o we_o sit_v or_o lie_v still_o much_o more_o must_v the_o high_a charm_n of_o opium_n cause_n it_o that_o it_o be_v a_o pleasure_n that_o affect_v by_o one_o of_o our_o sense_n namely_o by_o feel_v be_v indisputable_a for_o it_o be_v not_o a_o pleasure_n of_o the_o eye_n nose_n tongue_n or_o ear_n and_o it_o must_v be_v sensitive_a because_o cause_v by_o matter_n and_o that_o opium_n have_v doubtless_o the_o like_a effect_n upon_o brute_n who_o have_v no_o other_o pleasure_n but_o what_o be_v sensitive_a that_o it_o be_v at_o stomach_n be_v also_o evident_a where_o we_o can_v be_v please_v only_o by_o the_o sense_n of_o feel_v that_o it_o be_v involuntary_a and_o please_v we_o whether_o we_o will_v or_o no_o and_o that_o the_o same_o particle_n excite_v venery_n itch_a etc._n etc._n now_o all_o the_o sense_n especial_o feel_v and_o particular_o that_o at_o stomach_n be_v give_v we_o for_o
watch_n and_o sentinel_n to_o discover_v and_o give_v notice_n of_o what_o be_v or_o be_v not_o good_a and_o agreeable_a to_o our_o animal_n nature_n that_o upon_o notice_n of_o what_o be_v good_a and_o agreeable_a pleasure_n comfort_n satisfaction_n etc._n etc._n be_v conceive_v otherwise_o displeasure_n discomfort_n and_o dissatisfaction_n what_o diminish_v or_o disable_v our_o spirit_n do_v we_o the_o great_a evil_n that_o can_v be_v and_o consequent_o sensation_n will_v according_a to_o its_o office_n give_v we_o such_o notice_n thereof_o as_o will_v cause_v displeasure_n etc._n etc._n otherwise_o these_o sentinel_n that_o god_n and_o nature_n have_v appoint_v for_o faithful_a notice_n will_v instead_o of_o trusty_a service_n which_o be_v the_o end_n they_o be_v make_v for_o deceive_v we_o and_o consequent_o do_v we_o mischief_n rather_o than_o good_a which_o be_v very_o profane_a if_o not_o blasphemous_a to_o assert_v as_o be_v high_o abusive_a of_o god_n goodness_n and_o wisdom_n to_o make_v thing_n in_o nature_n that_o will_v not_o only_o not_o answer_n but_o act_n quite_o contrary_a to_o their_o end_n it_o follow_v then_o that_o what_o cause_v such_o a_o mighty_a agreeable_a and_o pleasant_a sensation_n at_o stomach_n which_o be_v the_o great_a and_o most_o accurate_a judge_n of_o what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n can_v be_v destructive_a or_o disable_n of_o its_o spirit_n which_o be_v the_o most_o excellent_a and_o useful_a thing_n that_o belong_v thereto_o therefore_o opium_n which_o so_o mighty_o recommend_v itself_o to_o please_v and_o comfort_v the_o great_a judge_n that_o god_n have_v give_v to_o a_o sensible_a creature_n to_o discern_v what_o be_v good_a and_o evil_a for_o it_o can_v diminish_v or_o disable_v our_o spirit_n one_o may_v say_v what_o i_o dare_v not_o that_o the_o sensation_n at_o stomach_n may_v deceive_v we_o we_o may_v deceive_v ourselves_o and_o say_v so_o when_o that_o which_o please_v the_o stomach_n do_v not_o please_v our_o pervert_v imagination_n which_o make_v no_o argument_n let_v we_o therefore_o consider_v thing_n where_o there_o be_v no_o such_o vain_a imagination_n to_o contradict_v the_o good_a end_n of_o nature_n if_o the_o stomach_n and_o sense_n in_o a_o brute_n or_o mere_a animal_n which_o have_v no_o other_o mean_n to_o judge_n of_o what_o be_v good_a or_o evil_n for_o it_o shall_v not_o judge_v aright_o all_o the_o animal_n in_o the_o whole_a world_n will_v soon_o perish_v it_o be_v the_o vain_a opinion_n of_o man_n that_o persuade_v they_o that_o thing_n be_v cold_a when_o hot_a etc._n etc._n as_o in_o the_o case_n of_o opium_n when_o the_o sense_n true_o inform_v that_o it_o be_v hot_a if_o you_o will_v stand_v to_o your_o imagination_n and_o supposition_n for_o such_o all_o must_v be_v without_o the_o information_n of_o sense_n against_o the_o dictate_v of_o sensation_n you_o must_v inevitable_o err_v but_o one_o may_v say_v be_v the_o sense_n at_o stomach_n such_o a_o infallible_a guide_n always_o i_o believe_v it_o will_v be_v very_o hard_a to_o give_v many_o instance_n to_o the_o contrary_a and_o prove_v it_o well_o however_o if_o we_o do_v or_o may_v allow_v something_o of_o this_o kind_a to_o a_o pervert_v stomach_n at_o certain_a time_n to_o avoid_v a_o squabble_n about_o it_o it_o be_v never_o to_o be_v allow_v that_o all_o the_o stomach_n in_o the_o whole_a world_n shall_v be_v please_v with_o one_o and_o the_o same_o thing_n at_o all_o time_n and_o yet_o that_o this_o thing_n shall_v be_v so_o high_o pernicious_a to_o the_o animal_n as_o to_o diminish_v or_o disable_v its_o spirit_n then_o indeed_o it_o will_v follow_v that_o the_o most_o exquisite_a sense_n at_o stomach_n to_o discern_v what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n be_v absolute_o in_o vain_a which_o no_o man_n of_o reason_n that_o have_v any_o apprehension_n of_o the_o wisdom_n of_o god_n and_o nature_n can_v assert_v 3._o what_o be_v more_o notorious_a than_o that_o pleasure_n or_o be_v please_v raise_v and_o displeasure_n or_o be_v grieve_v depress_n the_o spirit_n be_v not_o all_o people_n pleasant_a gay_a and_o good_a humour_a brisk_a prompt_a etc._n etc._n when_o please_v do_v not_o man_n travel_v or_o labour_n with_o more_o ease_n in_o pleasant_a company_n etc._n etc._n but_o of_o these_o matter_n and_o the_o reason_n thereof_o more_o in_o the_o follow_a chapter_n 4._o how_o can_v opium_n that_o revive_v people_n when_o they_o be_v so_o dispirited_a that_o they_o be_v even_o almost_o die_v as_o when_o opium_n be_v want_v by_o such_o as_o use_v to_o take_v it_o in_o deliquiâ—ms_n and_o agony_n from_o paiâ—_n etc._n etc._n diminish_v or_o disable_v the_o spirit_n it_o be_v plain_a contradiction_n to_o say_v that_o it_o shall_v next_o to_o opium_n nothing_o revive_v people_n in_o such_o case_n better_o than_o wine_n and_o those_o thing_n that_o produce_v the_o same_o or_o like_a effect_n have_v like_o nature_n and_o who_o can_v say_v that_o wine_n that_o be_v make_v to_o glad_a the_o heart_n of_o man_n diminish_v or_o disable_v the_o spirit_n or_o that_o opium_n which_o produce_v all_o the_o sprightly_a enliven_a and_o encourage_v effect_n of_o generous_a wine_n in_o a_o more_o eminent_a manner_n than_o wine_n and_o in_o the_o 10000th_o part_n of_o its_o quantity_n and_o for_o a_o long_a time_n than_o wine_n cause_v they_o shall_v diminish_v or_o disable_v the_o spirit_n for_o instance_n wine_n and_o opium_n in_o a_o due_a quantity_n but_o opium_n in_o a_o far_o less_o quantity_n as_o be_v say_v cause_v a_o pleasant_a gay_a and_o good_a humour_n courage_n bravery_n magnanimity_n promptitude_n in_o business_n expediteness_n in_o management_n serenity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n fatigue_n etc._n etc._n both_o take_v away_o sadness_n grief_n melancholy_n fear_v depression_n of_o spirit_n etc._n etc._n both_o cause_n promptitude_n to_o venery_n sine_fw-la cerere_fw-la &_o baccho_fw-la friget_fw-la venus_n so_o wine_n and_o opium_n prevent_v and_o cure_v cold_a open_v the_o pore_n promote_v perspiration_n and_o sweat_n especial_o the_o follow_a morning_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v of_o opium_n and_o be_v notorious_a as_o to_o wine_n both_o cause_n sleep_n and_o take_v away_o the_o sense_n of_o pain_n and_o require_v a_o great_a dose_n than_o ordinary_a in_o proportion_n to_o the_o pain_n both_o take_v off_o shivering_n from_o fear_n cold_a or_o ague_n fit_n and_o cause_n mirth_n contentation_n and_o acquiescence_n dryness_n of_o the_o mouth_n thirst_v a_o sense_n of_o heat_n within_o we_o a_o dream_v condition_n pleasant_a dream_n if_o the_o quantity_n of_o wine_n be_v not_o grievous_a by_o its_o heat_n load_n etc._n etc._n nocturnal_a pollution_n and_o in_o some_o constitution_n both_o cause_n vigilancy_n but_o wine_n and_o opium_n cause_v that_o more_o rare_o than_o sleep_n both_o stop_n and_o cause_n vomit_v if_o they_o stay_v too_o long_o at_o stomach_n both_o moderate_a hunger_n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d and_o be_v good_a in_o a_o canine_a appetite_n both_o cause_n swim_v in_o the_o head_n etc._n etc._n so_o both_o in_o a_o excessive_a do_v do_v cause_n at_o first_o mirth_n and_o afterward_o a_o kind_n of_o drunken_a soper_n in_o some_o in_o other_o fury_n or_o madness_n sardonick_a laughter_n and_o weight_n at_o stomach_n vomit_n hiccough_n great_a heat_n at_o stomach_n debility_n and_o laxity_n of_o all_o part_n falter_v of_o the_o tongue_n scotomy_n and_o darkness_n of_o the_o eye_n vertigo_n laxity_n of_o the_o cornea_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la deadness_n of_o the_o eye_n to_o the_o view_n loss_n of_o memory_n venereal_a fury_n a_o high_a colour_n profuse_a sweat_v purge_v sometime_o alienation_n of_o the_o mind_n loss_n of_o memory_n and_o last_o great_a or_o lesser_a effect_n according_a to_o the_o do_v constitution_n etc._n etc._n so_o a_o long_a and_o lavish_a use_n of_o both_o cause_n a_o dull_a and_o moapish_a disposition_n dropsy_n fall_v of_o humour_n upon_o weaken_v part_n a_o sleepy_a disposition_n want_v of_o appetite_n weakness_n of_o digestion_n aptitude_n to_o sterility_n and_o abortion_n early_a decrepiteness_n stoop_v in_o the_o back_n tremble_v of_o the_o hand_n weakness_n of_o memory_n shortness_n of_o life_n difficulty_n and_o danger_n in_o sudden_o leave_v they_o off_o revive_v such_o as_o sink_v for_o want_n of_o either_o and_o supply_v the_o want_n of_o each_o other_o how_o can_v any_o have_v the_o face_n to_o say_v that_o a_o thing_n which_o agree_v so_o with_o generous_a wine_n in_o effect_n can_v be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n the_o mischief_n of_o excessive_a dose_n and_o lavish_a use_n of_o either_o be_v no_o argument_n against_o their_o inspirit_a nature_n if_o it_o be_v than_o wine_n be_v no_o cordial_n though_o make_v to_o glad_a the_o heart_n
sensation_n of_o the_o sensile_a part_n which_o can_v well_o happen_v in_o that_o sound_a sleep_n wherein_o there_o be_v so_o little_a feel_v by_o reason_n of_o the_o say_a relaxation_n and_o because_o relaxation_n oppose_v contraction_n by_o which_o that_o shiver_a be_v promote_v such_o a_o relaxation_n and_o failure_n of_o feel_v thereupon_o be_v the_o true_a cause_n why_o opium_n put_v off_o ague_n fit_n etc._n etc._n so_o 20._o the_o relaxation_n in_o sleep_n stop_v vomit_v by_o take_v away_o the_o sense_n of_o the_o irritate_v cause_n and_o quiet_v as_o i_o have_v intimate_v all_o motion_n in_o general_a so_o sleep_v stop_n hiccough_n hemorrhage_n diary_n fever_n etc._n etc._n 21._o why_o watch_v labour_n or_o what_o impair_v the_o spirit_n and_o tire_v the_o sensitive_a soul_n incline_v we_o to_o sleep_v that_o be_v dispose_v the_o sensitive_a soul_n the_o only_a feeler_n of_o lassitude_n to_o give_v over_o contract_n the_o sensile_a part_n which_o as_o will_v plain_o appear_v by_o and_o by_o spend_v the_o spirit_n as_o sleep_v by_o relax_v they_o cause_v a_o recruit_v thereof_o to_o be_v short_a though_o one_o can_v hardly_o be_v too_o long_o in_o solve_v phenomena_n which_o be_v the_o proof_n of_o the_o truth_n of_o a_o man_n assertion_n the_o mechanical_a demonstration_n that_o i_o have_v make_v of_o the_o state_n of_o sleep_v and_o wake_v do_v so_o evident_o explicate_v all_o the_o phenomena_n of_o both_o that_o i_o be_o even_o ashamed_a to_o run_v any_o far_o upon_o such_o plain_a matter_n so_o obvious_a be_v thing_n when_o the_o truth_n be_v know_v and_o therefore_o have_v mention_v those_o circumstance_n and_o effect_n of_o sleep_n that_o main_o concern_v we_o i_o must_v give_v over_o lest_o the_o world_n shall_v think_v that_o i_o take_v all_o my_o reader_n to_o be_v idiot_n by_o use_v too_o many_o word_n in_o so_o obvious_a a_o thing_n or_o that_o i_o be_o no_o better_o for_o use_v they_o without_o cause_n for_o the_o truth_n of_o this_o matter_n seem_v to_o i_o to_o outshine_v all_o the_o argument_n i_o can_v make_v for_o it_o such_o splendour_n do_v truth_n show_v upon_o the_o first_o glimpse_n thereof_o as_o i_o take_v the_o account_n i_o give_v of_o sleep_n and_o watch_v to_o be_v for_o the_o opinion_n i_o have_v meet_v concern_v they_o be_v quite_o contrary_a to_o or_o very_o remote_a from_o what_o i_o have_v state_v 1._o they_o go_v quite_o contrary_a to_o it_o that_o say_v that_o the_o animal_n spirit_n be_v expanded_a and_o the_o pore_n of_o the_o brain_n etc._n etc._n more_o open_a and_o consequent_o more_o lax_n in_o watch_v as_o willis_n and_o several_a other_o who_o therefore_o say_v that_o coffee_n volatile_a salt_n etc._n etc._n be_v antihypnotick_n or_o good_a against_o too_o much_o sleepiness_n because_o they_o cause_v a_o expansion_n of_o the_o spirit_n and_o open_v the_o pore_n of_o the_o brain_n suppose_v forsooth_o that_o they_o march_v up_o and_o down_o and_o so_o keep_v the_o great_a stir_n upon_o the_o false_a imagination_n of_o their_o road_n be_v more_o open_a which_o as_o be_v prove_v be_v real_o more_o close_a coffee_n keep_v we_o from_o sleep_n by_o dry_v bind_a and_o both_o way_n constr_v the_o vessel_n as_o also_o by_o a_o wide_a grate_a quality_n which_o therefore_o do_v irritate_fw-la they_o to_o contract_v beside_o that_o the_o saline_n particle_n cause_v a_o agitation_n may_v contribute_v thereto_o so_o that_o by_o constr_v and_o agitate_v it_o direct_o oppose_v sleep_n which_o proceed_v from_o relaxation_n and_o quietness_n 2._o they_o be_v very_o remote_a from_o the_o mark_n that_o say_v as_o wedeliâ—s_a assert_n all_o do_v that_o vapour_n be_v the_o cause_n of_o natural_a sleep_n which_o bear_v no_o manner_n of_o proportion_n thereto_o as_o be_v show_v as_o they_o be_v also_o who_o mâ—dly_o talk_v that_o the_o animal_n spirit_n which_o have_v neither_o life_n sense_n motion_n or_o election_n do_v of_o themselves_o retire_v very_o know_o to_o the_o brain_n in_o sâ—eep_n and_o leave_v the_o limb_n etc._n etc._n destitute_a of_o they_o whereas_o as_o have_v be_v mechanical_o prove_v they_o have_v more_o room_n than_o that_o at_o other_o time_n in_o 〈◊〉_d limb_n and_o all_o the_o sensile_a part_n but_o i_o will_v not_o argue_v against_o such_o senseless_a and_o precarious_a absurdity_n it_o be_v not_o worth_a the_o while_n especial_o since_o the_o truth_n be_v manifest_o discover_v it_o will_v not_o have_v be_v so_o silly_a to_o have_v affirm_v the_o quite_o contrary_a viz._n that_o the_o animal_n spirit_n be_v force_v into_o the_o soft_a and_o yield_a brain_n in_o watch_v by_o the_o vigilative_a contraction_n of_o all_o the_o senfile_v part_n repel_v they_o as_o when_o cold_a repel_v they_o by_o a_o strong_a contraction_n of_o the_o part_n and_o cause_v a_o stupor_n or_o sleep_n thereof_o as_o they_o call_v it_o but_o what_o have_v we_o to_o do_v with_o such_o insufferable_a trash_n therefore_o bid_v it_o adieu_n let_v we_o pursue_v our_o business_n that_o it_o be_v the_o sensitive_a soul_n and_o nothing_o but_o it_o have_v that_o contract_n power_n be_v evident_a 1._o because_o it_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n as_o such_o and_o that_o nothing_o beside_o it_o have_v any_o life_n perception_n motion_n or_o power_n and_o therefore_o must_v rest_v till_o they_o be_v move_v 2._o because_o that_o when_o the_o sensitive_a soul_n be_v divert_v by_o intense_a pleasure_n from_o attend_v his_o business_n immediate_o relaxation_n follow_v as_o in_o the_o pleasure_n of_o the_o act_n of_o venery_n by_o wine_n joy_n etc._n etc._n in_o which_o you_o have_v all_o the_o effect_n of_o relaxation_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la plentiful_a perspiration_n floridity_n of_o the_o skin_n a_o large_a pulse_n and_o sometime_o a_o considerable_a failure_n of_o sense_n and_o motion_n as_o in_o the_o most_o pleasant_a time_n of_o the_o venereal_a act_n deliquiums_n drunkenness_n syncopes_fw-la or_o ecstasy_n upon_o intense_a pleasure_n which_o be_v very_o proper_o call_v ecstasy_n leipothymy_n leipopsychy_n etc._n etc._n which_o signify_v the_o soul_n leave_v we_o without_o his_o help_n by_o contraction_n which_o he_o then_o do_v not_o exercise_n as_o be_v charm_v and_o whole_o take_v up_o with_o pleasure_n this_o be_v the_o true_a cause_n of_o all_o deliquium_n etc._n etc._n upon_o pleasure_n joy_n etc._n etc._n all_o which_o cause_n great_a relaxation_n and_o thereby_o loss_n of_o sense_n and_o motion_n as_o be_v its_o necessary_a consequence_n 3._o because_o grievous_a sensation_n which_o belong_v only_o to_o the_o sensitive_a soul_n put_v we_o immediate_o out_o of_o sleep_n into_o a_o vigilative_a contraction_n 4._o because_o the_o sensitive_a soul_n can_v when_o we_o be_v sleepy_a oppose_v it_o by_o continue_v the_o vigilative_a contraction_n which_o prove_v vigilative_a contraction_n to_o be_v in_o his_o power_n note_v that_o there_o be_v also_o other_o sort_n of_o leipothymy_n deliquium_n etc._n etc._n upon_o the_o sensitive_a soul_n be_v overtired_n whereof_o natural_a sleep_n be_v but_o a_o common_a and_o ordinary_a degree_n that_o happen_v of_o course_n for_o our_o relief_n or_o overbear_v with_o some_o fatigue_n etc._n etc._n as_o when_o somewhat_o grieve_v at_o stomach_n and_o that_o it_o have_v lay_v about_o it_o all_o manner_n of_o way_n by_o vomit_v convulsive_a motion_n etc._n etc._n to_o be_v rid_v of_o it_o till_o it_o can_v work_v no_o long_o whereupon_o it_o lay_v down_o the_o cudgel_n desi_v from_o all_o further_a endeavour_n by_o contraction_n yield_v itself_o to_o ease_n see_v all_o strive_v be_v to_o no_o effect_n so_o that_o though_o this_o deliquium_fw-la and_o the_o former_a differ_v in_o their_o first_o cause_n yet_o do_v they_o agree_v in_o the_o last_o and_o immediate_a viz._n the_o sensitive_a soul_n be_v not_o attend_v his_o business_n of_o contraction_n whereupon_o follow_v a_o mighty_a relaxation_n as_o appear_v by_o the_o deadness_n or_o relaxation_n of_o the_o cornea_n dilatation_n of_o the_o pupil_n a_o great_a laxity_n of_o all_o part_n a_o large_a pulse_n or_o none_o very_o plentiful_a perspiration_n stop_v of_o hemorrhage_n and_o all_o flux_n that_o require_v contraction_n etc._n etc._n which_o happen_v both_o upon_o the_o account_n of_o the_o great_a relaxation_n itself_o as_o have_v be_v show_v and_o the_o almost_o absolute_a rest_n of_o all_o thing_n by_o the_o sensitive_a soul_n withdraw_a himself_n from_o business_n more_o than_o in_o sleep_n itself_o i_o therefore_o observe_v the_o degree_n of_o sleep_n etc._n etc._n do_v note_n that_o god_n and_o nature_n use_v a_o due_a proportion_n in_o all_o thing_n the_o sensitive_a soul_n use_v several_a degree_n of_o relaxation_n according_a as_o he_o be_v tire_v and_o refection_n be_v want_v hence_o it_o be_v that_o such_o as_o be_v much_o tire_v sleep_n more_o profound_o that_o our_o first_o
by_o squeeze_v in_o some_o case_n and_o stop_v it_o by_o shut_v the_o pore_n in_o other_o case_n 10._o it_o be_v by_o it_o that_o contraction_n that_o fear_v cold_a etc._n etc._n close_v the_o pore_n and_o repel_v the_o blood_n staunch_a bleed_a so_o happen_v also_o a_o great_a contraction_n of_o the_o pupil_n of_o the_o eye_n by_o the_o same_o cause_n 11._o it_o be_v the_o violence_n of_o this_o contraction_n upon_o fear_n terror_n pain_n cold_a etc._n etc._n close_v the_o small_a vessel_n of_o the_o animal_n spirit_n and_o thereby_o repel_v they_o cause_v the_o shiver_a in_o those_o case_n by_o the_o renitency_n of_o the_o elastic_a animal_n spirit_n spring_v back_o again_o toties_fw-la quoties_fw-la have_v gain_v more_o elastic_a force_n by_o the_o very_a compression_n itself_o which_o that_o contraction_n cause_n so_o that_o by_o reason_n of_o the_o dubious_a velitation_n or_o skirmish_v between_o the_o repel_v contraction_n and_o the_o spring_a spirit_n happen_v a_o tremulous_a motion_n as_o of_o quaver_v spring_n which_o shiver_a in_o ague-fits_a do_v former_o lead_v i_o to_o the_o situation_n of_o the_o cause_n of_o ague_n when_o i_o write_v my_o book_n de_fw-fr febribus_fw-la intermittentibus_fw-la in_o the_o angustiae_fw-la at_o the_o end_n of_o the_o vessel_n which_o terminate_v in_o the_o membrane_n the_o grievous_a sensation_n of_o which_o cause_v all_o the_o shiver_a that_o happen_v in_o any_o case_n to_o animal_n 12._o by_o the_o same_o contraction_n when_o very_o violent_a and_o of_o the_o whole_a body_n cold_a sweat_v happen_v in_o pain_n fear_v terror_n etc._n etc._n while_o it_o violent_o squeeze_v out_o the_o outmost_a and_o therefore_o cold_a moisture_n of_o our_o body_n as_o laundress_n do_v water_n out_o of_o wet_a linen_n by_o contortion_n thus_o if_o you_o dip_v one_o half_a of_o a_o wet_a cold_a sheet_n in_o hot_a water_n wrap_v the_o hot_a side_n within_o the_o cold_a or_o let_v a_o warm_a sheet_n that_o be_v contort_a cool_a on_o the_o outside_n of_o it_o and_o then_o wring_v it_o as_o woman_n do_v linen_n the_o water_n that_o first_o exudate_n will_v be_v cold_a for_o in_o this_o case_n the_o close_n of_o the_o pore_n avail_v nothing_o to_o hinder_v it_o as_o long_o as_o the_o express_a force_n master_n it_o more_o especial_o in_o animal_n body_n wherein_o the_o part_n be_v so_o contrive_v that_o humour_n design_v for_o exoretion_n can_v well_o return_v and_o therefore_o must_v upon_o contraction_n run_v out_o hence_o it_o be_v that_o alum_n or_o vitriol_n which_o be_v very_o astringent_a and_o therefore_o close_a the_o pore_n will_v notwithstanding_o cause_v the_o mouth_n or_o nose_n to_o run_v very_o plentiful_o with_o moisture_n by_o contract_v all_o the_o membrane_n about_o the_o mouth_n or_o nose_n and_o thereby_o squeeze_v out_o the_o moisture_n design_v to_o be_v excern_v which_o can_v return_v because_o the_o part_n be_v contrive_v against_o the_o return_n or_o readmittance_n thereof_o whereas_o alum_n or_o vitriol_n will_v staunch_v or_o stop_v blood_n by_o the_o same_o contraction_n because_o it_o may_v return_v as_o not_o be_v design_v to_o be_v excern_v either_o into_o the_o artery_n and_o so_o pass_v by_o other_o branch_n thereof_o or_o which_o be_v more_o ready_a and_o natural_a keep_v its_o course_n into_o the_o vein_n so_o the_o two_o riddle_n that_o i_o have_v know_v some_o proud_a physician_n amaze_v at_o though_o but_o trifle_n of_o alum_n and_o vitriol_n cause_v the_o spital_n etc._n etc._n to_o come_v out_o instead_o of_o stop_v it_o by_o their_o astringency_n and_o their_o stop_a blood_n at_o nose_n at_o the_o same_o time_n they_o cause_v the_o snot_n or_o other_o humour_n to_o run_v out_o be_v unfold_v 13._o it_o be_v by_o this_o mighty_a contraction_n grow_v to_o a_o enormous_a degree_n that_o the_o animal_n spirit_n be_v violent_o compress_v grow_v exceed_o irrequiete_a as_o upon_o convulsion_n in_o great_a pain_n or_o very_o grievous_a sensation_n at_o stomach_n etc._n etc._n while_o the_o sensitive_a soul_n compress_v they_o with_o mighty_a force_n and_o somewhat_o disorderly_a and_o uneven_o because_o of_o the_o confusion_n and_o hurry_n he_o be_v in_o to_o relieve_v the_o animal_n they_o by_o their_o springiness_n fling_v up_o and_o down_o with_o great_a vigour_n this_o make_v convulsive_a motion_n have_v great_a strength_n 14._o the_o body_n under_o this_o contraction_n be_v manifest_o shrink_v by_o measure_n especial_o when_o the_o sensation_n be_v very_o grievous_a but_o most_o of_o all_o if_o they_o cause_v a_o general_a convulsion_n which_o i_o manifest_o observe_v in_o a_o little_a bitch_n that_o be_v convulsive_a all_o over_o for_o three_o hour_n and_o be_v just_a expire_n when_o i_o give_v she_o the_o sal_fw-la volat._n oleo_n of_o opium_n which_o perfect_o restore_v she_o by_o relax_v the_o vessel_n some_o may_v think_v it_o strange_a that_o nature_n shall_v contrive_v a_o more_o nice_a and_o smart_a sensation_n which_o the_o contraction_n of_o the_o vessel_n of_o the_o animal_n spirit_n must_v cause_v by_o compress_v they_o etc._n etc._n in_o pain_n and_o by_o it_o which_o become_v so_o much_o the_o more_o acute_a whereas_o one_o will_v judge_v that_o nature_n will_v rather_o contrive_v its_o ease_n than_o improve_v its_o smart_n you_o be_v to_o know_v that_o the_o pain_n be_v in_o order_n to_o relieve_v the_o animal_n by_o exciting_a all_o its_o power_n to_o defend_v expel_v or_o reject_v the_o cause_n and_o that_o without_o a_o grievous_a sensation_n the_o sensitive_a soul_n be_v neither_o mind_v nor_o excite_v to_o do_v it_o and_o the_o more_o the_o pain_n be_v the_o more_o it_o be_v stir_v up_o to_o self-preservation_n and_o as_o be_v show_v the_o more_o vigorous_a do_v its_o motion_n grow_v by_o the_o compression_n of_o the_o elastic_a spirit_n to_o perform_v that_o work_n so_o nature_n not_o regard_v the_o pain_n which_o be_v rather_o for_o good_a as_o much_o as_o take_v away_o the_o cause_n advance_v that_o for_o this_o purpose_n like_o a_o wise_a physician_n who_o find_v a_o grievance_n at_o stomach_n not_o sufficient_a to_o excite_v effectual_a vomit_v to_o throw_v away_o the_o grieve_v cause_n add_v to_o the_o grievance_n by_o give_v a_o vomit_n which_o because_o as_o be_v say_v nature_n be_v proportionable_o excite_v to_o and_o invigorate_v for_o self-preservation_n sufficient_o solicit_v and_o enable_v it_o by_o a_o strong_a contraction_n to_o reject_v the_o grieve_v matter_n as_o the_o great_a the_o relaxation_n be_v the_o more_o be_v the_o rest_n of_o all_o part_n and_o the_o weak_a the_o animal_n spirit_n because_o less_o compress_v the_o gentle_a be_v all_o motion_n as_o you_o see_v in_o sleep_n consequent_o the_o less_o be_v the_o expense_n of_o spirit_n so_o that_o in_o sleep_n we_o generate_v more_o than_o we_o spend_v and_o be_v thereby_o recruit_v so_o the_o more_o the_o contraction_n be_v the_o more_o violent_a be_v the_o motion_n of_o the_o heart_n intestine_n and_o of_o all_o part_n and_o consequent_o the_o expense_n of_o spirit_n be_v the_o great_a therefore_o it_o can_v be_v no_o wonder_n that_o contraction_n do_v cause_n great_a commotion_n of_o spirit_n diary_n fever_n etc._n etc._n when_o you_o consider_v 1._o that_o the_o sensitive_a soul_n be_v by_o the_o grievous_a sensation_n etc._n etc._n that_o cause_n they_o put_v upon_o a_o great_a fret_v concern_v and_o hurry_v to_o defend_v the_o animal_n and_o lay_v about_o he_o all_o manner_n of_o way_n for_o self-preservation_n 2._o that_o the_o animal_n spirit_n be_v by_o mean_n of_o great_a compression_n cause_v by_o the_o defensive_a contraction_n in_o a_o very_a forcible_a springiness_n which_o cause_v all_o the_o action_n that_o be_v continual_a involuntary_a and_o of_o course_n to_o be_v perform_v with_o great_a violence_n proportionable_a to_o its_o compress_a elasticity_n beside_o that_o 3._o the_o systole_n of_o the_o heart_n be_v oftener_o repeat_v all_o which_o conspire_v to_o cause_v great_a commotion_n upon_o grievous_a sensation_n whereby_o diary_n fever_n etc._n etc._n be_v cause_v which_o be_v easy_o and_o natural_o cure_v by_o sleep_n or_o relaxation_n at_o present_a compose_v and_o quiet_v those_o perturbation_n who_o know_v though_o it_o be_v not_o my_o business_n to_o discuss_v it_o at_o present_a but_o that_o the_o contraction_n in_o the_o cold_a fit_n of_o ague_n have_v a_o great_a hand_n in_o cause_v the_o hot_a one_o how_o otherwise_o shall_v opium_n by_o only_o take_v away_o the_o grievous_a sensation_n of_o the_o cold_a fit_n take_v off_o or_o prevent_v the_o hot_a fit_n also_o but_o of_o this_o in_o my_o often-mentioned_n tract_n though_o not_o so_o often_o as_o it_o grieve_v i_o that_o it_o be_v not_o publish_v how_o reasonable_o may_v we_o now_o expect_v that_o pleasant_a sensation_n may_v cause_v quite_o contrary_a effect_n to_o that_o of_o grievous_a sensation_n viz._n relaxation_n and_o all_o its_o effect_n
be_v well_o remove_v this_o prove_v how_o useful_a removal_n may_v be_v and_o how_o convenient_a in_o plague_n time_n it_o will_v be_v to_o remove_v to_o the_o wind-side_n of_o a_o town_n or_o city_n that_o be_v taint_v according_a as_o the_o wind_n change_v and_o how_o convenient_a wind_n be_v to_o convey_v away_o the_o effluviams_n and_o good_a stomachick_a cordial_n that_o be_v warm_a and_o pleasant_a to_o fortify_v the_o stomach_n and_o open_v the_o pore_n which_o all_o thing_n that_o cause_v a_o sense_n of_o pleasure_n do_v as_o wine_n spirit_n etc._n etc._n to_o which_o if_o some_o good_a preparation_n of_o opium_n be_v add_v it_o will_v be_v most_o convenient_a how_o many_o story_n have_v we_o of_o person_n well_o fill_v with_o wine_n who_o wonderful_o escape_v infection_n i_o pray_v god_n this_o hint_n may_v be_v improve_v to_o the_o preservation_n of_o mankind_n therefore_o i_o add_v that_o much_o may_v be_v in_o a_o good_a quantity_n of_o wine_n in_o this_o case_n 1._o because_o quod_fw-la intus_fw-la est_fw-la prohibet_fw-la alienum_fw-la that_o be_v what_o be_v within_o hinder_v ingress_n of_o another_o thing_n 2._o because_o the_o perspiration_n will_v be_v the_o great_a both_o upon_o the_o account_n of_o the_o great_a open_n of_o the_o pore_n by_o the_o pleasure_n of_o the_o wine_n and_o the_o great_a quantity_n of_o matter_n to_o be_v perspire_v carry_v off_o the_o venomous_a particle_n 3._o because_o the_o sensitive_a soul_n be_v thereby_o much_o comfort_v refresh_v and_o invigorate_v but_o i_o will_v have_v the_o wine_n so_o use_v as_o to_o keep_v a_o continual_a warmth_n pleasure_n and_o comfort_n at_o stomach_n which_o be_v the_o main_a cause_n of_o all_o the_o good_a i_o think_v a_o glass_n every_o hour_n after_o take_v 2_o or_o 3_o at_o first_o may_v hit_v the_o mark_n best_o the_o reason_n of_o which_o will_v appear_v hereafter_o three_o the_o stomach_n be_v exquisite_a disposition_n to_o sensation_n above_o all_o other_o organ_n and_o membrane_n appear_v by_o this_o viz._n that_o the_o offence_n of_o the_o other_o organ_n of_o sensation_n even_o by_o their_o proper_a object_n do_v often_o affect_v the_o stomach_n more_o than_o those_o very_a sense_n or_o organ_n themselves_o for_o instance_n if_o we_o smell_v a_o great_a stench_n the_o stomach_n be_v often_o more_o offend_v thereat_o than_o the_o nose_n as_o be_v manifest_a from_o the_o vomit_n faint_n and_o deliquium_n that_o be_v cause_v by_o the_o stomach_n upon_o that_o account_n so_o the_o bare_a see_v feel_v and_o taste_v of_o a_o nasty_a thing_n do_v cause_n nauseas_fw-la etc._n etc._n at_o stomach_n yea_o the_o very_a name_n of_o such_o thing_n have_v much_o offend_v it_o and_o cause_v such_o effect_n which_o may_v be_v think_v very_o strange_a consider_v that_o there_o pass_v no_o effluvias_fw-la from_o the_o sound_n of_o word_n but_o the_o reason_n will_v appear_v in_o the_o follow_a paragraph_n four_o all_o passion_n commotion_n and_o perturbation_n that_o happen_v in_o the_o body_n do_v often_o affect_v the_o stomach_n and_o sometime_o so_o grievous_o as_o to_o cause_n nauseas_fw-la vomit_n great_a anxiety_n at_o stomach_n faint_n etc._n etc._n thus_o fear_v terror_n surprise_v anger_n grief_n pain_n in_o other_o part_n etc._n etc._n cause_v some_o motion_n in_o the_o animal_n more_o than_o ordinary_a of_o which_o the_o stomach_n be_v sensible_a do_v cause_n the_o aforesaid_a disturbance_n therefore_o it_o be_v no_o wonder_n if_o the_o hear_v one_o mention_n a_o nasty_a thing_n which_o cause_v a_o abhorrence_n and_o the_o motion_n consequent_a thereunto_o shall_v as_o be_v say_v in_o the_o precedent_n paragraph_n cause_v the_o nice_a stomach_n to_o be_v offend_v it_o be_v most_o manifest_a from_o the_o premise_n that_o no_o organ_n or_o membrane_n can_v compare_v with_o the_o stomach_n as_o to_o its_o exquisite_a disposition_n for_o sensation_n it_o follow_v then_o that_o grievance_n or_o pleasure_n at_o stomach_n must_v have_v the_o great_a effect_n 1._o because_o the_o intenseness_n of_o either_o will_v be_v proportionable_a to_o the_o sensation_n 2._o because_o the_o power_n of_o the_o animal_n that_o be_v to_o defend_v it_o which_o be_v contraction_n be_v affect_v according_a to_o the_o sensation_n and_o that_o it_o be_v there_o most_o requisite_a sensible_o to_o affect_v they_o 3._o because_o what_o affect_v the_o stomach_n influence_n the_o whole_a animal_n more_o than_o the_o sensation_n of_o any_o other_o part._n 4._o because_o of_o the_o considerable_a stay_v that_o thing_n make_v at_o stomach_n to_o cause_n grievance_n or_o pleasure_n whereas_o that_o of_o pleasure_n be_v general_o very_o momentary_a in_o other_o case_n 5._o because_o be_v within_o the_o body_n we_o carry_v our_o pleasure_n or_o grievance_n with_o we_o as_o a_o vade_fw-la mecum_fw-la wherever_o we_o go_v and_o therefore_o 6._o it_o be_v a_o pleasure_n etc._n etc._n that_o can_v so_o well_o be_v take_v away_o from_o we_o as_o that_o of_o the_o tongue_n ear_n nose_n eye_n etc._n etc._n may_v by_o remove_v the_o object_n and_o therefore_o it_o remain_v with_o we_o in_o our_o very_a sleep_n as_o far_o as_o we_o be_v capable_a of_o sensation_n at_o that_o time_n cause_v pleasant_a dream_n etc._n etc._n and_o so_o agreeable_o entertain_v we_o sleep_v or_o wake_v when_o the_o pleasure_n of_o all_o the_o other_o sense_n fail_v we_o which_o will_v appear_v far_o hereafter_o the_o pleasure_n at_o stomach_n excel_v even_o that_o of_o venery_n if_o not_o in_o intenseness_n yet_o in_o several_a other_o respect_n viz._n 1._o because_o of_o its_o duration_n that_o of_o venus_n be_v momentary_a but_o that_o of_o wine_n at_o stomach_n last_v a_o good_a while_n and_o that_o of_o opium_n many_o hour_n it_o be_v therefore_o that_o the_o effect_n of_o these_o two_o be_v more_o remarkable_a and_o take_v notice_n of_o 2._o because_o that_o at_o stomach_n may_v be_v continue_v as_o long_o as_o we_o please_v by_o a_o new_a supply_n of_o wine_n opium_n cordial_n etc._n etc._n 3._o because_o it_o may_v be_v excite_v when_o and_o as_o often_o as_o we_o please_v if_o we_o have_v those_o cordial_n at_o hand_n 4._o because_o it_o be_v not_o attend_v with_o any_o expense_n of_o strength_n depression_n of_o spirit_n etc._n etc._n as_o that_o of_o venery_n but_o the_o quite_o contrary_a viz._n with_o more_o vigour_n elevation_n of_o the_o spirit_n etc._n etc._n one_o be_v by_o emission_n and_o the_o other_o upon_o admission_n of_o what_o be_v agreeable_a it_o be_v for_o the_o several_a reason_n contain_v in_o the_o premise_n that_o the_o effect_n of_o grievance_n as_o hunger_n etc._n etc._n or_o pleasure_n be_v more_o considerable_a and_o remarkable_a at_o stomach_n and_o that_o thing_n agreeable_a thereto_o have_v by_o way_n of_o eminence_n gain_v the_o name_n of_o cordial_n that_o wine_n spirit_n opium_n etc._n etc._n do_v cause_n a_o more_o permanent_a and_o notable_a gaity_n pleasantness_n good_a humour_n serenity_n promptitude_n ovation_n of_o the_o spirit_n or_o sensitive_a soul_n bravery_n courage_n magnanimity_n euphory_n or_o easy_a undergo_n of_o business_n relaxation_n with_o all_o its_o effect_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la perspiration_n etc._n etc._n which_o be_v hardly_o note_v in_o other_o short_a pleasure_n unless_o it_o be_v in_o that_o eminent_a though_o short_a one_o of_o venus_n which_o be_v a_o pleasure_n of_o the_o same_o sense_n of_o feel_v as_o that_o of_o opium_n and_o wine_n be_v therefore_o please_v the_o stomach_n be_v one_o of_o the_o great_a thing_n to_o be_v regard_v in_o the_o practice_n of_o physic_n to_o comfort_n satisfy_v or_o compose_v the_o spirit_n by_o which_o mean_n i_o have_v often_o perform_v such_o cure_n that_o neither_o i_o nor_o i_o suppose_v any_o other_o can_v otherwise_o perform_v namely_o dejection_n of_o appetite_n untowardness_n at_o stomach_n etc._n etc._n when_o all_o the_o ordinary_a and_o usual_a mean_n have_v fail_v by_o ask_v they_o what_o they_o most_o desire_a or_o long_v for_o and_o let_v they_o have_v it_o or_o if_o they_o can_v not_o tell_v of_o any_o thing_n that_o they_o long_v for_o i_o have_v mention_v to_o they_o all_o the_o relish_v thing_n that_o i_o can_v think_v of_o and_o such_o as_o be_v grateful_a to_o the_o stomach_n till_o they_o fasten_v upon_o somewhat_o that_o they_o like_v or_o fancy_v and_o then_o be_v give_v they_o it_o general_o have_v the_o desire_a success_n the_o stomach_n be_v grieve_v for_o it_o will_v concern_v we_o to_o know_v how_o because_o opium_n cause_v vomit_v etc._n etc._n general_o speak_v 1._o by_o thing_n hard_a of_o digestion_n as_o heavy_a bread_n mushroom_n rosin_n and_o such_o like_a 2._o by_o thing_n acrimonious_a or_o pungent_a as_o vomitory_n of_o asarabacca_n groundsil_n squill_n etc._n etc._n which_o abound_v with_o volatile_a salt_n 3._o by_o thing_n that_o stick_v to_o the_o stomach_n which_o
often_o cause_v most_o dismal_a and_o tedious_a vomit_n and_o when_o they_o fall_v to_o relieve_v by_o reject_v the_o grieve_v matter_n hiccough_v anxiety_n distress_n syncopes_fw-la and_o sometime_o fatal_a succumbency_n nature_n and_o all_o endeavour_n fail_v to_o work_v any_o far_o for_o the_o animal_n relief_n these_o thing_n happen_v most_o common_o when_o indigeslible_a rosin_n stick_v to_o the_o stomach_n especial_o if_o they_o be_v join_v with_o any_o pungent_a volatile_a or_o acrimonious_a particle_n hence_o it_o be_v that_o resinous_n vomit_n be_v quite_o banish_v out_o of_o the_o practice_n of_o physic_n and_o it_o be_v well_o if_o resinous_n purger_n be_v so_o also_o especial_o such_o as_o have_v considerable_a acrimony_n unless_o give_v with_o the_o yolk_n of_o a_o egg_n lixivial_n or_o in_o tincture_n with_o spirituous_a thing_n to_o keep_v the_o resinous_n particle_n from_o coalescence_n and_o adhere_v to_o the_o stomach_n etc._n etc._n 1._o note_v for_o we_o shall_v have_v some_o occasion_n for_o it_o that_o resinous_n thing_n join_v with_o volatile_a irritate_v particle_n have_v all_o the_o ill_a quality_n aforemention_v viz._n hardness_n of_o digestion_n aptitude_n to_o stick_v to_o the_o stomach_n and_o volatile_a particle_n to_o irritate_fw-la and_o tear_v its_o coat_n all_o the_o time_n they_o so_o stick_v to_o it_o and_o therefore_o such_o thing_n have_v dismal_a effect_n especial_o in_o weak_a stomach_n that_o can_v digest_v they_o 2._o note_v that_o the_o distress_n at_o stomach_n cause_v by_o a_o grievous_a sensation_n be_v of_o two_o sort_n 1._o such_o as_o be_v the_o endeavour_n of_o nature_n or_o the_o sensitive_a soul_n in_o defence_n of_o the_o animal_n as_o all_o vomit_n purge_n convulsion_n hiccough_n throw_n struggle_n agitation_n contraction_n watch_n etc._n etc._n which_o be_v accompany_v with_o melancholy_a fretfulness_n ill_a humour_n etc._n etc._n because_o of_o the_o grievance_n 2._o such_o as_o follow_v the_o yield_v and_o succumbency_n of_o nature_n or_o the_o sensitive_a soul_n after_o be_v tire_v and_o overbear_v by_o the_o fatigue_n of_o defensive_a contraction_n as_o faint_n distress_n agony_n syncopes_fw-la and_o leipothymy_n 3._o note_v that_o syncopes_fw-la or_o leipothymy_n be_v cause_v by_o the_o sensitive_a soul_n be_v overbear_v as_o be_v say_v tire_v and_o spend_v and_o give_v over_o his_o fruitless_a contraction_n defensive_a and_o vigilative_a upon_o a_o sudden_a as_o be_v to_o no_o purpose_n as_o he_o do_v gentle_o and_o gradual_o give_v over_o vigilative_a contraction_n to_o cause_n sleep_n so_o that_o syncopes_fw-la be_v only_o great_a sudden_a and_o more_o absolute_a dereliction_n of_o the_o whole_a concern_v of_o contraction_n hence_o it_o be_v that_o perspiration_n be_v great_a in_o syncopes_fw-la or_o leipothymy_n than_o in_o sleep_n the_o laxity_n of_o the_o cornea_n and_o the_o whole_a body_n great_a the_o feel_v less_o or_o quite_o go_v that_o all_o motion_n become_v much_o slow_a or_o none_o by_o the_o want_n of_o compression_n of_o the_o animal_n spirit_n and_o dismal_a dereliction_n of_o all_o contraction_n by_o the_o sensitive_a soul_n hence_o it_o be_v that_o all_o the_o effect_n of_o sleep_n be_v yet_o great_a in_o syncopes_fw-la 4._o note_v that_o therefore_o it_o seem_v all_o the_o difference_n between_o sleep_n and_o a_o leipothymy_n be_v that_o in_o this_o the_o sensitive_a soul_n quite_o throw_v the_o reins_o of_o contraction_n away_o and_o in_o sleep_n keep_v hold_v thereof_o and_o only_o let_v they_o loose_a and_z as_o refection_n be_v make_v straighten_v they_o more_o and_o more_o till_o they_o come_v to_o the_o degree_n of_o vigilative_a contraction_n which_o perfect_o awake_v they_o therefore_o sleep_n grow_v slight_a towards_o morning_n because_o contraction_n gradual_o come_v on_o here_o you_o may_v see_v but_o i_o must_v stop_v lest_o i_o run_v too_o far_o why_o every_o thing_n that_o cause_v contraction_n of_o the_o sensile_a part_n as_o pain_n and_o all_o grievance_n be_v apt_a to_o awake_a people_n and_o keep_v they_o so_o as_o relaxer_n cause_v sleep_n and_o continue_v it_o 5._o note_v that_o though_o i_o have_v particular_o speak_v of_o the_o somach_n as_o be_v most_o concern_v and_o the_o best_a example_n of_o any_o membrane_n yet_o do_v not_o i_o exclude_v any_o membrane_n from_o be_v capable_a of_o pleasure_n by_o the_o like_a thing_n as_o for_o the_o effect_n of_o pleasure_n upon_o the_o sensitive_a soul_n i_o have_v upon_o several_a occasion_n say_v or_o intimate_v enough_o concern_v they_o and_o even_o the_o vulgar_a know_v that_o pleasure_n or_o be_v please_v make_v people_n good_a and_o gay_a humour_a that_o it_o elevate_v the_o spirit_n raise_v courage_n as_o wine_n do_v and_o enable_v every_o animal_n to_o labour_n or_o travel_v the_o better_a as_o horse_n by_o the_o sound_n of_o bell_n especial_o if_o tuneable_a and_o in_o company_n with_o another_o horse_n that_o they_o have_v a_o kindness_n for_o how_o soldier_n march_v more_o easy_o with_o merry_a comrade_n that_o be_v full_a of_o jest_n and_o pleasant_a story_n or_o with_o drum_n trumpets_z kettle_z drums_z 〈◊〉_d and_o other_o music_n that_o please_v the_o ear_n how_o much_o more_o briâ—k_n and_o blithe_a be_v we_o in_o a_o fair_a sunshine_n which_o please_v the_o eye_n than_o at_o other_o time_n some_o â—ink_n according_a to_o the_o vulgar_a error_n that_o iâ—_n be_v the_o goodness_n of_o the_o air_n do_v it_o but_o it_o be_v plain_o otherwise_o for_o you_o find_v the_o change_n most_o remarkable_a in_o yourself_o just_a upon_o go_v out_o of_o door_n into_o the_o sunshine_n whereas_o you_o have_v the_o same_o air_n in_o your_o chamber_n nor_o be_v that_o fine_a lightness_n of_o humour_n to_o be_v find_v if_o it_o be_v cloudy_a though_o the_o air_n be_v better_o as_o may_v be_v observe_v by_o the_o barometer_n and_o other_o weather-glass_n nor_o in_o the_o night_n time_n nor_o where_o the_o sun_n do_v not_o come_v nor_o be_v blind_a people_n so_o affect_v therefore_o it_o be_v the_o pleasure_n of_o the_o bright_a sunshine_n that_o cause_v it_o if_o mean_a 'slight_o transient_a and_o external_n pleasure_n cause_v such_o effect_n how_o much_o more_o than_o will_v a_o intense_a internal_a and_o continue_a pleasure_n upon_o the_o most_o exquisite_o dispose_v part_n for_o sensation_n of_o all_o the_o whole_a body_n which_o be_v main_o design_v for_o those_o purpose_n of_o please_a and_o comfort_v to_o invite_v we_o to_o nourish_v ourselves_o and_o to_o satisfy_v the_o grievous_a sensation_n of_o hunger_n and_o thirst_n by_o the_o pleasure_n of_o meat_n and_o drink_n such_o pleasant_a effect_n thus_o the_o fretfulness_n peevishness_n ill_a humour_n melancholy_n pusillanimity_n inaptitude_n and_o listnesness_n that_o attend_v the_o grievous_a sensation_n of_o hunger_n be_v take_v off_o and_o cure_v by_o the_o pleasant_a sensation_n that_o a_o good_a meal_n or_o some_o glass_n of_o wine_n do_v cause_n hence_o it_o be_v that_o we_o can_v sleep_v when_o hungry_a because_o grievous_a sensation_n contract_v the_o sensile_a part_n and_o be_v apt_a to_o it_o after_o meal_n the_o pleasure_n of_o which_o relax_n we_o if_o we_o sit_v or_o lie_v quiet_o and_o silent_o but_o if_o we_o do_v not_o we_o be_v more_o lively_a and_o fit_a for_o business_n instance_n of_o this_o kind_a be_v so_o numerous_a and_o notorious_a that_o i_o need_v say_v no_o more_o of_o the_o effect_n of_o pleasure_n in_o cause_v a_o good_a humour_n elevation_n of_o the_o spirit_n satisfaction_n content_a composure_n etc._n etc._n be_v it_o possible_a that_o one_o shall_v be_v high_o please_v and_o not_o take_v comfort_n therein_o take_v comfort_n and_o not_o be_v elevate_v in_o spirit_n well_o satisfy_v and_o content_v therefore_o it_o be_v strange_a and_o very_o strange_a that_o people_n shall_v leave_v wine_n cordial_n meat_n spirit_n etc._n etc._n actual_o and_o sensible_o please_v satisfy_a and_o comfort_v we_o at_o stomach_n where_o there_o be_v a_o membrane_n most_o exquisite_o dispose_v for_o sensation_n and_o run_v after_o fume_n and_o effluvias_fw-la that_o be_v never_o in_o our_o case_n in_o be_v to_o the_o brain_n or_o blood_n that_o have_v no_o sense_n to_o entertain_v they_o and_o consequent_o can_v receive_v no_o sensible_a comfort_n by_o they_o if_o this_o be_v not_o seek_v a_o needle_n in_o a_o bottle_n of_o hay_n where_o it_o never_o be_v when_o it_o stick_v most_o sensible_o in_o their_o finger_n nothing_o be_v we_o shall_v think_v it_o a_o strange_a ridiculous_a action_n in_o a_o child_n or_o natural_a fool_n but_o great_a be_v the_o privilege_n and_o authority_n of_o the_o learned_a so_o much_o may_v suffice_v as_o to_o the_o effect_n of_o pleasure_n upon_o the_o sensitive_a soul_n as_o for_o the_o effect_n of_o pleasure_n upon_o the_o body_n it_o be_v relaxation_n of_o all_o the_o sensile_a part_n thereof_o as_o appear_v 1._o because_o it_o be_v contrary_a viz._n displeasure_n or_o sensitive_a
spoon_n and_o cause_n no_o more_o effect_n than_o oil_n of_o olive_n and_o spirit_n of_o sal_fw-la amenoniack_a take_v inward_o one_o act_v too_o soft_o lazy_o and_o greasy_o to_o cause_v any_o brisk_a and_o agreeable_a ovation_n of_o the_o spirit_n and_o the_o other_o too_o rude_o sting_v the_o membrane_n therefore_o we_o must_v proceed_v in_o our_o enquiry_n four_o opium_n have_v a_o sort_n of_o resinous_n sulphur_n that_o be_v loose_a and_o not_o unite_v with_o the_o volatile_a salt_n which_o plain_o appear_v 1._o because_o if_o you_o dissolve_v opium_n in_o water_n cold_a or_o hot_a or_o any_o watery_a menstruum_fw-la you_o will_v find_v a_o good_a quantity_n of_o rosin_n undissolved_a at_o bottom_n while_o the_o volatile_a salt_n be_v all_o or_o most_o dissolve_v in_o the_o water_n especial_o if_o the_o water_n be_v often_o repeat_v and_o quite_o separate_v from_o the_o resinous_n part_v which_o subside_v without_o any_o more_o trouble_n which_o show_v that_o the_o volatile_a salt_n and_o it_o be_v not_o combine_v but_o in_o a_o very_a loose_a and_o distinct_a manner_n 2._o because_o if_o you_o first_o dissolve_v opium_n in_o spirit_n of_o wine_n which_o imbibe_v the_o rosin_n it_o be_v easy_o again_o precipitate_v by_o plain_a water_n leave_v behind_o it_o all_o or_o most_o of_o the_o volatile_a salt_n in_o the_o form_n of_o a_o red_a tincture_n in_o the_o menstruum_fw-la as_o it_o do_v also_o in_o the_o former_a case_n note_v that_o the_o resinous_n part_n of_o opium_n have_v no_o effect_n as_o a_o opiate_n for_o if_o it_o be_v well_o wash_v with_o water_n as_o be_v say_v it_o have_v no_o operation_n of_o that_o kind_n or_o so_o little_a that_o it_o be_v not_o worth_a the_o mind_v but_o all_o the_o virtue_n specific_a taste_n smell_v etc._n etc._n be_v carry_v away_o in_o that_o red_a tincture_n which_o have_v all_o the_o good_a effect_n of_o opium_n as_o experience_n assure_v we_o 3._o because_o if_o opium_n be_v very_o much_o torrefy_v most_o of_o the_o volatile_a salt_n be_v evaporate_v and_o with_o it_o most_o if_o not_o all_o the_o virtue_n of_o opium_n but_o the_o rosin_n remain_v as_o a_o deadish_a stuff_n in_o respect_n of_o the_o good_a effect_n of_o opium_n though_o it_o be_v as_o shall_v be_v prove_v the_o producer_n of_o the_o ill_a effect_n thereof_o therefore_o this_o rosin_n must_v be_v whole_o reject_v five_o the_o red_a tincture_n aforesaid_a have_v all_o or_o most_o of_o the_o volatile_a salt_n in_o it_o 1._o because_o water_n be_v the_o proper_a menstruum_fw-la for_o saline_n thing_n and_o that_o the_o tincture_n reduce_v to_o a_o extract_n give_v very_o much_o in_o moist_a wether_n which_o quality_n it_o must_v have_v from_o the_o volatile_a salt_n because_o it_o have_v very_o little_o fix_v salt_n 2._o because_o the_o specific_a bitterness_n which_o proceed_v from_o volatile_a salt_n and_o oily_a part_n be_v whole_o in_o that_o red_a tincture_n 3._o because_o that_o tincture_n have_v also_o the_o specific_a rankness_n of_o smell_n that_o the_o volatile_a salt_n as_o be_v show_v give_v the_o opium_n by_o the_o help_n of_o some_o oily_a part_n 4._o because_o that_o tincture_n reduce_v to_o a_o extract_n have_v the_o bite_a taste_n of_o opium_n which_o as_o be_v show_v proceed_v from_o its_o volatile_a salt_n 5._o because_o that_o extract_n incides_fw-la discuss_n resolve_n be_v psilothrick_n titillate_n to_o venery_n cause_v itch_n in_o the_o skin_n acrimonious_a sweat_v etc._n etc._n all_o which_o be_v as_o be_v show_v the_o effect_n of_o volatile_a salt_n but_o what_o need_v i_o insist_v so_o much_o upon_o its_o effect_n to_o prove_v it_o when_o 6._o it_o appear_v by_o crystalization_n of_o the_o say_a tincture_n after_o it_o have_v be_v evaporate_v to_o a_o due_a degree_n that_o it_o contain_v the_o volatile_a salt_n in_o it_o which_o in_o a_o cool_a place_n shoot_v to_o elegant_a crystal_n and_o that_o 7._o it_o be_v find_v therein_o by_o chemical_a operation_n by_o fire_n six_o the_o say_a tincture_n be_v oleose_v 1._o because_o the_o redness_n of_o the_o tincture_n must_v be_v from_o oily_a part_n for_o pure_a sincere_a volatile_a salt_n give_v no_o such_o tincture_n 2._o because_o it_o be_v bitter_a one_o ingredient_n of_o which_o taste_n be_v ever_o oily_a part_n as_o be_v say_v 3._o because_o of_o its_o rank_a smell_n like_o sem._n viril_n which_o prove_v it_o to_o be_v sulphureous_a for_o the_o volatile_a salt_n alone_o have_v only_o a_o quick_a smell_n or_o urinous_a at_o far_a 4._o because_o it_o be_v of_o a_o hot_a taste_n when_o reduce_v to_o a_o extract_n which_o heat_v of_o taste_n consider_v distinct_o from_o its_o pungent_a or_o bite_a taste_n must_v be_v from_o sulphureous_a or_o oily_a part_n 5._o because_o spirit_n of_o wine_n and_o other_o spirituosulphureous_a menstruum_n do_v ready_o dissolve_v it_o when_o reduce_v to_o a_o extract_n 6._o because_o the_o extract_n soften_v with_o dry_a warmth_n as_o sulphureous_a or_o oily_a thing_n do_v 7._o because_o a_o true_a sal-volatile-oleosum_a wherein_o the_o volatile_a salt_n and_o oily_a part_n be_v intimate_o combine_v as_o you_o find_v in_o all_o blood_n tincture_n of_o several_a plant_n that_o have_v such_o a_o sal-volatile-oleosum_a be_v red_a 8._o because_o it_o can_v not_o otherwise_o so_o fine_o please_v the_o membrane_n cause_n sleep_n compose_v the_o spirit_n etc._n etc._n if_o it_o be_v all_o volatile_a salt_n which_o be_v whole_o pungent_a and_o acrimonious_a mighty_o oppose_v sleep_n and_o cause_v a_o great_a stir_n in_o the_o blood_n and_o spirit_n but_o as_o i_o say_v as_o to_o its_o volatile_a salt_n what_o need_v i_o insist_v upon_o its_o effect_n when_o 10._o it_o be_v inflammability_n after_o it_o be_v reduce_v to_o a_o extract_n and_o dry_v put_v it_o out_o of_o all_o question_n and_o that_o 11._o a_o oil_n may_v be_v separate_v from_o the_o volatile_a salt_n though_o not_o without_o trouble_n because_o that_o as_o be_v requisite_a to_o complete_a it_o in_o the_o high_a degree_n seven_o the_o oily_a part_n and_o volatile_a salt_n be_v very_o intimate_o and_o strict_o combine_v as_o fair_o appear_v 1._o by_o the_o difficulty_n to_o separate_v they_o 2._o by_o the_o redness_n of_o the_o tincture_n as_o in_o blood_n etc._n etc._n for_o when_o oily_a or_o sulphureous_a particle_n be_v loose_a therein_o they_o make_v either_o a_o white_a colour_n as_o the_o rosin_n do_v in_o the_o drop_n that_o fall_v out_o of_o the_o incision_n in_o the_o head_n of_o the_o poppy_n which_o be_v milk_n white_a or_o leave_v the_o volatile_a spirit_n perspicuous_a as_o in_o a_o sort_n of_o artificial_a sal._n volatile-oleosum_a that_o be_v sell_v at_o the_o apothecary_n shop_n in_o london_n 3._o because_o it_o impart_v its_o tincture_n which_o depend_v upon_o both_o to_o all_o menstruum_n 4._o because_o it_o impart_v its_o virtue_n which_o depend_v upon_o both_o to_o all_o menstruum_n 5._o because_o it_o impart_v its_o specific_a smell_n which_o depend_v upon_o both_o to_o all_o menstruumt_v 6._o because_o it_o impart_v its_o specific_a hot_a and_o bite_a taste_n which_o depend_v upon_o both_o the_o oily_a and_o volatile_a particle_n to_o all_o menstruum_n 7._o because_o it_o will_v hold_v its_o virtue_n many_o year_n which_o it_o can_v not_o if_o the_o volatile_a salt_n and_o oily_a part_n be_v not_o very_o strict_o combine_v 8._o because_o that_o notwithstanding_o the_o digestion_n at_o stomach_n it_o have_v hold_v its_o specific_a virtue_n smell_v and_o taste_n after_o it_o have_v be_v in_o it_o 4_o 5_o 6_o 7_o 8_o 9_o 10_o 11_o 12_o 18_o or_o more_o hour_n as_o appear_v by_o its_o operate_n so_o long_o and_o afteward_n its_o be_v vomit_v up_o with_o the_o same_o taste_n and_o smell_v that_o it_o have_v at_o first_o than_o which_o there_o can_v be_v a_o great_a argument_n 9_o because_o it_o have_v be_v carry_v off_o by_o stool_n which_o have_v its_o specific_a smell_n after_o many_o hour_n remain_v in_o the_o stomach_n 10._o because_o its_o operation_n in_o general_n last_v long_o charas_fw-la mention_n one_o that_o it_o operate_v with_o for_o about_o 30_o hour_n and_o wedelius_n another_o who_o opium_n cause_v to_o vomit_v constant_o about_o 18_o hour_n after_o it_o be_v take_v 11._o because_o it_o have_v its_o effect_n upon_o the_o venereal_a membrane_n after_o it_o have_v pass_v the_o digestion_n at_o stomach_n the_o effect_n of_o the_o choler_n and_o succus_fw-la pancreatus_fw-la in_o the_o duodenum_fw-la be_v strain_v through_o the_o coat_n of_o the_o intestine_n into_o the_o lacteal_v and_o through_o the_o glandule_n of_o the_o mesentery_n mix_v and_o circulate_v with_o the_o blood_n etc._n etc._n 12._o because_o after_o all_o that_o it_o have_v its_o effect_n upon_o the_o skin_n by_o cause_v a_o itch_a therein_o 13._o because_o it_o not_o only_a cause_n acrimonious_a sweat_v but_o such_o as_o evident_o smell_v thereof_o
be_v repute_v opiate_n borellus_n speak_v of_o a_o soporiferous_a aura_n that_o proceed_v from_o one_o thumb_n cure_v by_o a_o caustick_a i_o have_v read_v of_o a_o cataphora_fw-it from_o worm_n a_o soporiferous_a fume_v from_o the_o womb_n and_o very_o many_o such_o sort_n of_o instance_n which_o thing_n be_v now_o easy_o conceive_v for_o it_o be_v but_o suppose_v a_o fume_v of_o the_o nature_n of_o sem._n animale_a or_o its_o aura_n for_o i_o can_v no_o long_o doubt_v but_o it_o be_v a_o opiate_n and_o it_o will_v have_v much_o the_o same_o effect_n with_o opium_n if_o it_o be_v fit_a to_o use_v it_o after_o the_o same_o manner_n have_v show_v 1._o which_o be_v the_o predominant_a active_a principle_n in_o opium_n and_o how_o combine_v etc._n etc._n 2._o which_o of_o they_o produce_v the_o usual_a and_o laudable_a effect_n of_o opium_n and_o why_o in_o general_a i_o come_v now_o to_o the_o three_o particular_a viz._n to_o show_v iii_o which_o of_o they_o produce_v its_o ill_a effect_n and_o why_o it_o be_v ill_a effect_n be_v these_o viz._n nauseas_fw-la vomit_n which_o be_v general_o very_o dismal_a with_o great_a distress_n and_o sometime_o dangerous_a swim_v in_o the_o head_n hiccough_n distress_n anxiety_n convulsion_n faint_n leipothymy_n syncopes_fw-la etc._n etc._n 1._o note_v that_o its_o grievous_a effect_n be_v at_o or_o about_o the_o region_n of_o the_o stomach_n or_o particular_o the_o mouth_n or_o pit_n thereof_o or_o thence_o arise_v by_o consent_n 2._o note_v that_o see_v there_o be_v nothing_o so_o good_a but_o may_v cause_v evil_a effect_n in_o a_o excessive_a quantity_n this_o enquiry_n be_v more_o proper_o what_o principle_n or_o principle_n of_o opium_n do_v cause_n those_o ill_a effect_n in_o a_o ordinary_a do_v for_o what_o will_v in_o a_o moderate_a do_v will_v be_v sure_a cause_v they_o in_o a_o excessive_a do_v 3._o note_v that_o all_o the_o constant_a effect_n of_o opium_n as_o you_o may_v observe_v in_o the_o enumeration_n thereof_o in_o the_o four_o chapter_n be_v good_a and_o laudable_a effect_n it_o follow_v therefore_o that_o the_o bad_a be_v accidental_a 1._o it_o be_v not_o the_o earthy_a or_o phlegmatic_a part_n of_o opium_n that_o cause_v those_o ill_a effect_n because_o they_o be_v passive_a principle_n and_o consequent_o have_v not_o such_o a_o power_n beside_o that_o they_o be_v know_v to_o be_v innocent_a 2._o opium_n have_v all_o those_o ill_a effect_n when_o both_o the_o earthy_a and_o phlegmatic_a part_n be_v separate_v from_o it_o as_o when_o a_o extract_v of_o well_o torrefy_v opium_n be_v make_v in_o spirit_n of_o wine_n for_o by_o that_o mean_v the_o phlegmatic_a part_n be_v dry_v up_o and_o the_o earthy_a part_n subside_o and_o be_v separate_v yea_o such_o extract_v make_v by_o spirit_n of_o wine_n do_v cause_n those_o evil_a effect_n rather_o more_o than_o crude_a opium_n with_o its_o earth_n and_o phlegm_n in_o it_o as_o experience_n assure_v we_o and_o reason_n will_v plain_o confirm_v by_o and_o by_o however_o fond_a the_o world_n be_v of_o such_o preparation_n 3._o it_o be_v evident_a from_o the_o premise_n that_o the_o sal-volatile-oleosum_a of_o opium_n can_v cause_v those_o vomit_n hiccough_n etc._n etc._n for_o they_o be_v the_o effect_n of_o grievous_a sensation_n at_o stomach_n but_o the_o sal-volatile-oleosum_a cause_n a_o most_o agreeable_a and_o please_a sensation_n at_o stomach_n 4._o nothing_o quiet_v vomit_n convulsion_n â—coughs_n etc._n etc._n more_o than_o that_o sal-volatile-oleosum_a of_o opium_n 5._o experience_n inform_v we_o that_o the_o sal-volatile-oleosum_a of_o opium_n separate_v from_o all_o other_o part_n and_o principle_n thereof_o never_o cause_v such_o evil_a effect_n as_o i_o and_o another_o physician_n in_o london_n can_v testify_v as_o do_v also_o le_fw-fr mort_fw-fr in_o the_o most_o learned_a dr._n love_n collectanea_fw-la where_o he_o say_v of_o such_o a_o preparation_n thereof_o as_o contain_v only_o the_o sal-volatile-oleosum_a that_o nunquam_fw-la anxietates_fw-la circa_fw-la praecordia_fw-la aut_fw-la phantasias_fw-la conciliat_fw-la that_o be_v it_o never_o cause_v anxiety_n about_o the_o mouth_n of_o the_o stomach_n etc._n etc._n for_o that_o be_v most_o proper_o to_o be_v understand_v by_o praecordia_fw-la wedelius_n testify_v the_o like_a of_o such_o another_o preparation_n and_o so_o do_v several_a author_n though_o they_o do_v not_o in_o the_o least_o know_v why_o but_o only_o by_o experience_n 6._o it_o be_v fix_v salt_n be_v innocent_a in_o its_o nature_n and_o but_o the_o 32d_o part_n of_o opium_n which_o be_v too_o inconsiderable_a in_o a_o ordinary_a moderate_a do_v to_o cause_v any_o sensible_a effect_n it_o follow_v therefore_o that_o be_v must_v be_v the_o resinous_n part_n of_o opium_n which_o it_o have_v in_o a_o considerable_a quantity_n that_o must_v cause_v those_o ill_a effect_n this_o manifest_o appear_v 1._o because_o a_o tincture_n of_o opiam_fw-la in_o water_n which_o take_v up_o none_o of_o the_o rosin_n but_o let_v it_o fall_v into_o the_o bottom_n never_o cause_v any_o such_o ill_a effect_n which_o it_o do_v not_o also_o if_o reduce_v to_o a_o extract_v by_o evaporation_n yet_o have_v they_o all_o the_o usual_a good_a effect_n of_o opium_n 2._o wedelius_n in_o his_o opiolog_n assure_v the_o same_o of_o the_o like_a preparation_n in_o phlegm_n of_o distil_a vinegar_n l._n 2._o sect._n 1_o c._n 5._o p._n 92._o 3._o a_o extract_v of_o opium_n in_o spirit_n of_o wine_n do_v often_o cause_v those_o ill_a effect_n and_o no_o other_o preparation_n cause_v they_o as_o often_o wedelius_n ibid._n a_o laudano_n opiato_fw-it cum_fw-la spiritu_fw-la vini_n correcto_fw-la solum_fw-la ferâ—_n observavimus_fw-la ortos_fw-la vomitus_fw-la a_o nostro_fw-la vero_fw-la quod_fw-la cum_fw-la phlegmate_fw-it aceti_fw-la distillati_fw-la fieri_fw-la diximus_fw-la nunquam_fw-la vomitum_fw-la vel_fw-la nauseam_fw-la saltem_fw-la contigisse_fw-la meminimus_fw-la that_o be_v we_o have_v observe_v vomit_n almost_o only_o from_o laudanum_n prepare_v with_o spirit_n of_o wine_n but_o never_o any_o vomit_v or_o nausea_n from_o that_o prepare_v in_o phlegm_n of_o distil_a vinegar_n which_o he_o confirm_v l._n 1._o sect_n 2._o c._n 4._o p._n 62._o saying_n in_o latin_a that_o a_o curious_a observation_n be_v to_o be_v note_v by_o which_o it_o appear_v that_o a_o extract_v of_o opium_n with_o spirit_n of_o wine_n show_v more_o narcotick_a force_n by_o which_o he_o mean_v that_o it_o cause_v more_o ill_a effect_n than_o prepare_v in_o distil_a vinegar_n whereas_o that_o in_o spirit_n of_o wine_n have_v nothing_o more_o in_o it_o than_o that_o in_o vinegar_n beside_o the_o râ—sinous_n part_n therefore_o these_o do_v cause_n all_o the_o mischief_n note_v also_o that_o a_o extract_v in_o spirit_n of_o wine_n have_v in_o it_o quantity_n for_o quantity_n more_o of_o the_o râ—sinous_n part_v than_o crude_a oplum_fw-la both_o because_o the_o earthy_a part_n that_o help_v to_o make_v up_o the_o bulk_n be_v take_v away_o in_o that_o preparation_n and_o because_o the_o 〈◊〉_d of_o wine_n imbibe_v the_o rosin_n more_o greedy_o than_o other_o principle_n of_o the_o opium_n so_o that_o every_o do_v must_v in_o proportion_n have_v much_o more_o rosin_n in_o it_o than_o crude_a opium_n therefore_o it_o be_v no_o wonder_n that_o it_o cause_v those_o ill_a effect_n more_o frequent_o since_o the_o rosin_n be_v most_o certain_o the_o cause_n thereof_o as_o have_v be_v and_o shall_v be_v more_o full_o and_o beyond_o all_o contradiction_n prove_v yet_o be_v this_o the_o preparation_n boast_v of_o by_o the_o blind_a and_o inadvertent_n world_n it_o will_v amaze_v nay_o terrify_v a_o man_n to_o see_v what_o great_a care_n be_v take_v to_o be_v sure_a to_o render_v opium_n mischievous_a by_o solicitous_o use_v spirit_n of_o wine_n in_o extract_a laudanum_n and_o then_o and_o not_o till_o then_o they_o boast_v of_o the_o preparation_n as_o charas_fw-la and_o very_o many_o other_o do_v calling_z it_o not_o without_o great_a ostentation_n and_o desperate_a folly_n their_o laudanum_n may_v it_o be_v they_o and_o none_o other_o a_o turk_n will_v be_v a_o madman_n to_o use_v it_o for_o crude_a opium_n because_o it_o have_v much_o more_o of_o the_o pernicious_a principle_n in_o it_o it_o be_v the_o common_a and_o much_o esteem_v way_n first_o to_o extract_v it_o out_o of_o water_n and_o then_o it_o be_v very_o good_a laudable_a and_o innocent_a but_o think_v nothing_o worth_a till_o they_o extract_v the_o rosin_n that_o be_v all_o leave_v behind_o by_o the_o water_n in_o spirit_n of_o wine_n and_o add_v it_o to_o the_o other_o then_o do_v they_o with_o great_a authority_n praise_v it_o that_o be_v when_o they_o have_v wise_o add_v the_o poison_n to_o the_o panacea_fw-la it_o be_v as_o if_o they_o add_v ratsbane_n to_o a_o cordial_n and_o not_o think_v the_o cordial_a worthy_a commendation_n till_o they_o have_v do_v so_o 4._o it_o appear_v that_o the_o rosin_n be_v
operate_v in_o a_o very_a small_a quantity_n as_o it_o usual_o do_v because_o the_o least_o matter_n imaginable_a affect_v the_o sense_n as_o have_v be_v show_v for_o the_o thousand_o part_n of_o a_o grain_n of_o ambergrise_n musk_n etc._n etc._n affect_v the_o smell_a the_o hundred_o part_n of_o a_o grain_n of_o very_a acrimonious_a thing_n the_o taste_n which_o cause_v very_o sensible_a pleasure_n or_o displeasure_n according_a as_o it_o be_v agreeable_a or_o not_o much_o easy_a may_v the_o exquisite_o dispose_v membrane_n at_o stomach_n which_o be_v affect_v with_o thing_n so_o indefinite_o small_a that_o no_o other_o sense_n or_o membrane_n can_v take_v notice_n of_o as_o the_o particle_n of_o crocus_n metallorum_fw-la in_o vomit_n effluvias_fw-la from_o a_o cat_n body_n pestiferous_a effluvias_fw-la and_o the_o like_a of_o all_o which_o the_o stomach_n be_v so_o sensible_a that_o they_o thereby_o cause_v most_o violent_a symptom_n which_o be_v as_o be_v show_v proportion_v to_o the_o sensation_n therefore_o it_o can_v be_v no_o wonder_n that_o a_o grain_n or_o less_o of_o opium_n shall_v affect_v the_o sensile_a coat_n of_o the_o stomach_n and_o thereby_o cause_v a_o sense_n of_o pleasure_n for_o that_o which_o be_v nice_a to_o discern_v grieve_v particle_n be_v so_o to_o discern_v please_v once_o as_o have_v be_v say_v cujus_fw-la est_fw-la dolour_n ejusdem_fw-la est_fw-la voluptus_fw-la that_o be_v pleasure_n and_o displeasure_n belong_v to_o the_o same_o part_n and_o as_o be_v show_v in_o equal_a degree_n this_o prove_v that_o it_o must_v operate_v by_o pleas_o affect_v the_o stomach_n for_o it_o be_v otherwise_o impossible_a that_o so_o little_a a_o quantity_n shall_v cause_v such_o remarkable_a effect_n and_o that_o before_o the_o opium_n be_v out_o of_o the_o stomach_n but_o it_o be_v ordinary_a for_o the_o stomach_n to_o cause_v mighty_a effect_n by_o its_o sensation_n of_o very_a small_a thing_n otherwise_o insensible_a and_o inconsiderable_a as_o to_o the_o production_n of_o any_o observable_a effect_n and_o therefore_o it_o will_v be_v a_o miracle_n if_o it_o do_v any_o other_o way_n cause_n such_o great_a and_o numerous_a effect_n helmont_n observe_v that_o pro_fw-la remedio_fw-la restaurativo_fw-la archaei_n sive_fw-la animae_fw-la sensitivae_fw-la non_fw-la requiritur_fw-la unciarum_fw-la &_o drachmarum_fw-la quantitas_fw-la sed_fw-la pauca_fw-la grana_n that_o be_v very_o little_a serve_v to_o comfort_v the_o archaeus_n or_o sensitive_a soul_n because_o it_o be_v do_v by_o sensation_n as_o i_o have_v prove_v 2._o it_o be_v as_o evident_a how_o a_o hot_a brisk_a and_o salino-volatile_a thing_n as_o opium_n be_v must_v affect_v the_o sensile_a coat_n of_o the_o stomach_n in_o a_o short_a time_n as_o vomit_n purger_n etc._n etc._n do_v which_o it_o do_v much_o in_o the_o same_o time_n with_o those_o thing_n that_o be_v as_o soon_o as_o they_o insinuate_v themselves_o through_o the_o crusta_fw-la carnosa_fw-la of_o the_o stomach_n and_o reach_v its_o sensile_a coat_n which_o be_v the_o reason_n that_o opium_n vomit_n purger_n etc._n etc._n make_v some_o and_o like_o delay_n before_o they_o operate_v which_o be_v also_o a_o proof_n that_o all_o of_o they_o operate_v by_o affect_v the_o sensile_a coat_n of_o the_o stomach_n all_o the_o difference_n be_v that_o one_o affect_v pleasant_o as_o wine_n meat_n and_o cordial_n and_o the_o other_o by_o a_o grievous_a sensation_n the_o explication_n of_o the_o constant_a effect_n of_o opium_n use_v internal_o etc._n etc._n 1._o the_o first_o and_o lead_v effect_n of_o opium_n be_v cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n this_o be_v a_o property_n that_o belong_v to_o it_o omni_n &_o semper_fw-la and_o indeed_o soli_fw-la to_o opiate_n if_o the_o degree_n duration_n and_o fineness_n of_o the_o pleasure_n be_v consider_v how_o manifest_a be_v it_o from_o what_o have_v be_v say_v of_o the_o most_o complete_a and_o consummate_v sal-volatile-oleosum_a of_o opium_n which_o exact_o agree_v in_o principle_n etc._n etc._n with_o semen_n animale_a that_o so_o high_o please_v and_o titillate_n the_o membrane_n with_o which_o it_o not_o only_o agree_v in_o principle_n as_o be_v show_v but_o have_v they_o more_o active_a actuate_a and_o titillate_v than_o any_o membrane_n that_o it_o must_v of_o necessity_n high_o please_v all_o membrane_n more_o especial_o such_o as_o be_v most_o exquisite_o dispose_v for_o sensation_n as_o the_o most_o sensile_a membrane_n at_o stomach_n be_v not_o only_o by_o its_o agreeableness_n but_o by_o a_o most_o charm_a and_o captivate_a titillation_n that_o actuate_v and_o cause_v a_o fine_a ovation_n and_o serene_a glow_a of_o the_o spiritus_fw-la insiti_fw-la of_o the_o stomach_n which_o make_v it_o please_v in_o the_o high_a manner_n have_v all_o the_o requisite_n to_o cause_n a_o sense_n of_o pleasure_n and_o that_o be_v not_o all_o but_o it_o be_v take_v into_o the_o body_n it_o cause_v a_o long_a continue_a and_o permanent_a sense_n of_o pleasure_n which_o we_o must_v necessary_o carry_v along_o with_o we_o as_o a_o vade_fw-la mecum_fw-la even_o sleep_v or_o wake_v rest_a or_o move_a or_o whatever_o we_o do_v or_o wherever_o we_o be_v by_o which_o mean_n it_o far_o excel_v all_o other_o pleasure_n and_o consequent_o produce_v such_o mighty_a effect_n all_o other_o pleasure_n be_v momentary_a transitory_a desultory_n or_o interrupt_v except_o that_o of_o wine_n and_o cordial_n at_o stomach_n which_o therefore_o have_v the_o like_a effect_n to_o that_o of_o opium_n though_o they_o do_v not_o equal_v it_o in_o the_o intenseness_n or_o duration_n of_o the_o pleasure_n unless_o they_o be_v repeat_v as_o indeed_o they_o may_v be_v which_o make_v i_o to_o intimate_v that_o drink_v a_o good_a glass_n of_o wine_n every_o hour_n and_o by_o that_o mean_n keep_v the_o fresh_a pleasure_n thereof_o continual_o at_o the_o stomach_n like_o that_o of_o opium_n be_v the_o best_a way_n to_o cause_v a_o long_a euphory_n of_o labour_n journey_n etc._n etc._n which_o may_v come_v near_o the_o performance_n of_o our_o divine_a sal-volatile-oleosum_a of_o opium_n though_o never_o equal_v it_o for_o reason_n already_o sufficient_o hint_v viz._n because_o wine_n want_v its_o most_o agreeable_a composition_n and_o fine_a titillation_n of_o the_o volatile_a salt_n that_o opium_n and_o animal_n seed_n have_v note_v that_o the_o pleasure_n of_o opium_n may_v to_o some_o inadvertent_n person_n seem_v very_o indefinite_a though_o it_o be_v at_o stomach_n as_o it_o must_v be_v because_o the_o pleasure_n immediate_o relax_v all_o part_n and_o gratify_v the_o sensitive_a soul_n which_o inform_v the_o whole_a seem_v to_o be_v general_a though_o original_o only_a at_o stomach_n 2._o our_o consummate_v sal-volatile-oleosum_a must_v cause_v a_o blithe_a gay_a and_o good_a humour_n for_o be_v please_v with_o any_o thing_n as_o be_v the_o vulgar_a observation_n cause_v a_o good_a humour_n how_o much_o more_o must_v such_o a_o intense_a agreeable_a and_o continual_a pleasure_n that_o we_o always_o and_o every_o where_o carry_v along_o with_o we_o so_o do_v how_o common_a a_o say_v be_v it_o he_o be_v please_v with_o somewhat_o for_o i_o find_v he_o in_o a_o good_a humour_n 3._o the_o like_a be_v to_o be_v say_v of_o its_o cause_v promptitude_n serenity_n alacrity_n and_o expediteness_n in_o dispatch_v and_o manage_n of_o business_n for_o these_o be_v but_o natural_a and_o necessary_a consequence_n of_o a_o blithe_a gay_a and_o good_a humour_n and_o therefore_o always_o go_v together_o for_o the_o sensitive_a soul_n be_v put_v in_o a_o fine_a ovation_n by_o the_o continual_a pleasure_n be_v more_o active_a and_o have_v thereupon_o as_o be_v show_v whole_o excuse_v himself_o from_o the_o care_n and_o solicitude_n of_o the_o defensive_a contraction_n and_o in_o great_a measure_n of_o the_o vigilative_a contraction_n also_o be_v more_o at_o leisure_n to_o attend_v the_o managery_n of_o other_o affair_n without_o distraction_n beside_o that_o he_o be_v actuate_v and_o enliven_v by_o the_o aforesaid_a ovation_n of_o the_o spirit_n and_o please_a titillation_n into_o a_o alacrity_n and_o promptitude_n for_o any_o business_n with_o which_o also_o he_o be_v less_o tire_v because_o he_o have_v as_o be_v say_v rid_v himself_o of_o the_o fatigue_n of_o the_o contraction_n that_o as_o be_v manifest_o prove_v do_v cause_n lassitude_n which_o otherwise_o can_v hardly_o touch_v or_o affect_v he_o at_o all_o in_o the_o state_n of_o relaxation_n 4._o it_o must_v cause_v assurance_n ovation_n of_o the_o spirit_n courage_n magnanimity_n as_o wine_n do_v by_o elevate_n the_o sensitive_a soul_n by_o pleasure_n and_o a_o high_a titillation_n of_o the_o spiritus_fw-la insiti_fw-la by_o its_o volatile_a part_n actuate_a they_o as_o the_o animal_n semen_n do_v all_o creature_n in_o time_n of_o copulation_n though_o it_o immediate_o affect_v only_o the_o venereal_a membrane_n but_o we_o do_v actuate_v they_o not_o
contraction_n by_o which_o vomit_v be_v perform_v 4._o it_o still_v hiccough_n for_o the_o same_o reason_n 5._o it_o cause_v convulsion_n and_o contraction_n to_o cease_v 1._o because_o it_o induce_v a_o relaxation_n which_o take_v they_o off_o 2._o by_o take_v off_o the_o sense_n which_o the_o irritate_v cause_n 3._o by_o compose_v the_o spirit_n 6._o it_o cause_v the_o meat_n to_o stay_v long_o at_o stomach_n as_o sleep_n do_v 1._o by_o relax_v the_o stomach_n so_o that_o it_o be_v not_o subject_a to_o contract_v to_o send_v it_o out_o 2._o by_o still_v all_o motion_n whereby_o the_o stomach_n grow_v proportionable_o unactive_a 3._o because_o the_o relaxation_n oppose_v the_o contraction_n by_o which_o the_o menstruum_fw-la be_v send_v into_o the_o stomach_n or_o the_o saliva_n into_o the_o mouth_n both_o which_o be_v therefore_o much_o want_v in_o sleep_n for_o the_o like_a reason_n as_o have_v be_v show_v 7._o it_o moderate_v and_o prevent_v hunger_n 1._o because_o as_o be_v say_v the_o menstruum_fw-la be_v not_o so_o plentiful_o send_v or_o squeeze_a into_o the_o relaxed_a stomach_n 2._o because_o it_o take_v away_o the_o sense_n of_o hunger_n 3._o because_o it_o leave_v the_o meat_n to_o stay_v too_o long_o at_o stomach_n by_o reason_n that_o it_o be_v relax_v more_o insensible_a and_o proportionable_o languid_a in_o motion_n as_o in_o sleep_n 8._o it_o cause_v sweat_v when_o the_o body_n be_v full_a of_o moisture_n as_o sleep_n do_v by_o relax_v and_o thereby_o open_v the_o pore_n and_o not_o as_o people_n common_o talk_v by_o attenuate_v and_o the_o like_a for_o a_o grain_n of_o opium_n bear_v no_o proportion_n to_o the_o blood_n and_o humour_n that_o it_o cause_v it_o mere_o as_o sleep_n do_v be_v manifest_a not_o only_o because_o it_o bear_v not_o a_o due_a proportion_n to_o the_o work_n as_o a_o alterative_a but_o because_o man_n do_v not_o sweat_v in_o that_o case_n as_o in_o sleep_n without_o much_o moisture_n in_o the_o body_n whereas_o much_o will_v not_o be_v attenuate_v as_o soon_o as_o less_o therefore_o it_o be_v only_o a_o exudation_n of_o the_o humour_n upon_o a_o plenty_n thereof_o and_o open_v of_o the_o pore_n sanctorius_n sect._n 1_o aph._n 22._o invisibilis_fw-la perspiratio_fw-la fit_a visibilis_fw-la quando_fw-la nutrimentum_fw-la est_fw-la nimium_fw-la that_o be_v invisible_a perspiration_n become_v visible_a sweat_n when_o nourishment_n or_o moisture_n be_v too_o much_o which_o exact_o agree_v with_o that_o of_o hypocrates_n cite_v in_o chap._n 13._o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d etc._n etc._n 9_o it_o cause_v the_o menses_fw-la to_o flow_v when_o nothing_o be_v want_v but_o the_o open_n or_o relax_v of_o the_o viae_fw-la or_o pore_n they_o issue_v out_o at_o as_o when_o they_o be_v natural_o too_o narrow_a and_o close_a as_o upon_o the_o first_o tendency_n to_o they_o in_o young_a girl_n or_o when_o stop_v by_o reason_n of_o any_o undue_a contraction_n thereof_o as_o by_o pain_n cold_a sorrow_n or_o other_o grievous_a passion_n all_o which_o do_v close_o the_o pore_n beside_o it_o do_v irritate_fw-la those_o very_a sensile_a venereal_a part_n to_o erection_n and_o i_o have_v reason_n to_o think_v that_o it_o do_v by_o a_o general_a relaxation_n cause_n a_o increase_n of_o blood_n as_o it_o do_v of_o the_o breast_n milk_n etc._n etc._n cause_v as_o it_o be_v a_o artificial_a puberty_n or_o at_o least_o much_o promote_a the_o natural_a and_o therefore_o be_v of_o excellent_a use_n in_o this_o case_n in_o judicious_a hand_n though_o little_a thought_n of_o in_o practice_n obj._n here_o i_o may_v be_v sure_a of_o a_o objection_n that_o it_o stop_v all_o flux_n but_o sweat_v or_o perspiration_n ans._n it_o be_v as_o false_a as_o it_o be_v a_o common_a say_n if_o they_o do_v not_o mean_v only_o such_o flux_n as_o proceed_v from_o grievous_a sensation_n and_o contraction_n thereupon_o for_o how_o can_v that_o which_o relax_n all_o part_n stop_v any_o flux_n that_o depend_v upon_o relaxation_n as_o stillicidium_fw-la urinae_fw-la by_o relaxation_n of_o the_o sphincter_n of_o the_o â—ladder_n involuntary_a flux_n per_fw-la anum_fw-la by_o the_o 〈◊〉_d of_o its_o sphincter_n and_o such_o like_a so_o do_v i_o speak_v of_o a_o flux_n that_o may_v often_o depend_v upon_o relaxation_n as_o i_o have_v show_v obj._n but_o it_o may_v be_v object_v that_o it_o particular_o stanche_n blood_n how_o then_o shall_v it_o promote_v the_o menses_fw-la ans._n experience_n tell_v i_o it_o do_v and_o reason_n confirm_v it_o it_o stanche_n blood_n by_o compose_v the_o fury_n of_o its_o motion_n but_o that_o do_v not_o hinder_v but_o it_o may_v relax_v the_o pore_n for_o sweat_n menses_fw-la lochia_n etc._n etc._n to_o pass_v and_o why_o not_o for_o the_o menses_fw-la and_o lochia_n as_o well_o as_o sweat_v by_o open_v the_o pore_n i_o will_v fain_o know_v consider_v also_o the_o titillation_n that_o it_o cause_n upon_o those_o venereal_a part_n which_o may_v very_o much_o solicit_v their_o motion_n 10._o it_o cause_v the_o lochia_n to_o flow_v for_o the_o same_o reason_n that_o it_o do_v the_o menses_fw-la this_o i_o have_v great_a experience_n in_o note_v that_o the_o menses_fw-la lochia_n and_o perspiration_n be_v natural_a evacuation_n that_o have_v pore_n design_v for_o they_o by_o nature_n the_o open_n of_o which_o by_o relaxation_n must_v make_v way_n for_o they_o suppose_v when_o the_o blood_n flow_v so_o much_o into_o the_o skin_n as_o to_o cause_v a_o efflorescence_n by_o the_o relaxation_n thereof_o after_o opium_n be_v take_v that_o there_o be_v pore_n to_o carry_v out_o blood_n as_o there_o be_v for_o sweat_n why_o shall_v not_o one_o flow_v as_o well_o as_o the_o other_o but_o there_o be_v such_o pore_n for_o the_o menses_fw-la and_o lochia_n and_o large_a one_o too_o and_o therefore_o it_o must_v promote_v they_o and_o why_o shall_v not_o relaxation_n do_v it_o as_o well_o as_o contraction_n by_o cold_a terror_n grief_n etc._n etc._n stop_v they_o for_o the_o effect_n of_o contrary_n be_v contrary_a 11._o it_o cause_v the_o stone_n to_o pass_v 1._o because_o it_o reâ—_n and_o so_o widen_v the_o passage_n 2._o because_o it_o 〈◊〉_d move_v with_o little_a or_o no_o pain_n which_o contract_v the_o part_n and_o so_o hinder_v its_o passage_n therefore_o the_o use_n of_o opium_n with_o some_o other_o help_v be_v the_o great_a mean_n that_o can_v be_v or_o ever_o will_v be_v for_o the_o stone_n till_o the_o dissolution_n of_o it_o be_v find_v out_o not_o only_o to_o give_v ease_n in_o the_o case_n of_o the_o stone_n but_o to_o cause_v it_o to_o pass_v for_o both_o which_o purpose_v it_o excel_v all_o thing_n and_o do_v both_o at_o once_o 12._o it_o cause_v the_o delivery_n of_o woman_n by_o relax_v the_o neck_n of_o the_o womb_n as_o it_o do_v that_o of_o the_o bladder_n to_o deliver_v person_n of_o the_o stone_n but_o in_o the_o delivery_n of_o woman_n it_o be_v not_o to_o be_v use_v but_o in_o particular_a case_n and_o by_o a_o very_a skilful_a hand_n 1._o because_o it_o be_v apt_a to_o take_v off_o all_o the_o woman_n pain_n and_o throw_v and_o so_o quite_o disappoint_v the_o delivery_n for_o a_o day_n 2_o 3_o 4_o or_o more_o sometime_o 2._o because_o it_o cause_v a_o great_a relaxation_n the_o part_n after_o delivery_n will_v be_v very_o unapt_a to_o close_v and_o contract_v due_o as_o they_o shall_v in_o such_o case_n otherwise_o several_a inconvenience_n may_v ensue_v 3._o it_o may_v be_v pernicious_a upon_o the_o account_n of_o the_o evacuation_n of_o blood_n that_o then_o happen_v but_o these_o thing_n belong_v more_o proper_o to_o the_o use_v of_o opium_n in_o cure_n 13._o it_o cause_v deadness_n of_o the_o eye_n as_o in_o drunkeness_n etc._n etc._n because_o the_o cornea_n be_v relax_v so_o that_o the_o humour_n do_v not_o fill_v it_o up_o to_o a_o tense_n rotundity_n as_o when_o it_o be_v more_o contract_v 14._o it_o cause_v the_o pupilla_fw-la to_o dilate_v because_o of_o the_o same_o relaxation_n 15._o it_o cause_v a_o growth_n of_o the_o breast_n penis_n and_o increase_v of_o milk_n by_o reason_n of_o the_o same_o relaxation_n as_o the_o pleasure_n of_o the_o semen_n upon_o puberty_n do_v or_o as_o emollient_n and_o relaxer_n apply_v to_o the_o breast_n increase_v milk_n etc._n etc._n by_o make_v more_o room_n for_o it_o etc._n etc._n 16._o it_o cause_v venereal_a dream_n because_o of_o the_o titillation_n of_o the_o venereal_a membrane_n that_o it_o cause_n 17._o it_o cause_v nocturnal_a pollution_n for_o the_o same_o reason_n and_o because_o it_o relax_n the_o part_n 18._o it_o cause_v itch_n in_o the_o skin_n because_o of_o its_o titillation_n by_o its_o volatile_a salt_n 19_o it_o cause_v much_o urine_n as_o cantbaride_n bee_n pismire_n millepedes_n etc._n etc._n do_v by_o its_o volatile_a salt_n which_o titillate_n and_o irritate_v those_o
part_n by_o its_o relax_v the_o pore_n of_o the_o kidney_n and_o render_v the_o humour_n more_o penetrate_v in_o some_o measure_n by_o the_o volatile_a salt_n 20._o it_o cause_v a_o nausea_n by_o its_o rosin_n stick_v to_o and_o teaze_v the_o sensile_a coat_n of_o the_o stomach_n the_o reason_n why_o it_o be_v general_o so_o long_o before_o it_o cause_v a_o nausea_n or_o vomit_v be_v that_o its_o pleasure_n do_v at_o first_o prevent_v it_o till_o at_o last_o the_o stick_a rosin_n urge_v it_o by_o its_o long_a stay_n and_o vexatious_a adherence_n 21._o it_o cause_v swimmings_n in_o the_o head_n by_o consent_n when_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o you_o find_v upon_o nauseas_fw-la before_o vomit_v or_o when_o any_o thing_n do_v much_o offend_v the_o stomach_n as_o much_o drink_n or_o wine_n which_o when_o they_o have_v vomit_v those_o swimming_n cease_v 22._o it_o cause_v watch_v in_o some_o person_n who_o be_v of_o very_o movable_a spirit_n by_o actuate_a and_o stir_v their_o spirit_n by_o its_o active_a volatile_a salt_n though_o it_o do_v at_o the_o same_o time_n please_v the_o membrane_n and_o consequent_o relax_v the_o sensile_a part_n and_o thereby_o cause_n indolence_n the_o effect_n of_o relaxation_n which_o it_o also_o do_v when_o people_n keep_v themselves_o from_o sleep_n by_o voluntary_a motion_n and_o therefore_o take_v away_o pain_n even_o when_o man_n travel_v etc._n etc._n beside_o there_o be_v some_o sort_n of_o person_n that_o upon_o joy_n good_a news_n pleasure_n or_o the_o like_a be_v too_o much_o elevate_v or_o have_v a_o restless_a ovation_n of_o the_o spirit_n which_o will_v not_o suffer_v they_o to_o sleep_n though_o they_o be_v in_o a_o pleasant_a condition_n all_o the_o time_n this_o may_v be_v the_o case_n of_o some_o that_o can_v sleep_v after_o opium_n though_o they_o be_v all_o the_o time_n as_o they_o call_v it_o in_o a_o heavenly_a condition_n for_o as_o i_o have_v say_v a_o quietness_n of_o the_o spirit_n be_v requisite_a to_o cause_v sleep_n as_o well_o as_o relaxation_n but_o relaxation_n alone_o and_o thereby_o expansion_n of_o the_o spirit_n so_o that_o they_o can_v carry_v impression_n smart_o be_v sufficient_a to_o cause_v indolence_n and_o the_o pleasure_n to_o cause_v a_o heavenly_a or_o very_o pleasant_a condition_n sanctor_n stat._n med._n sect._n 7._o aph._n 28._o say_v that_o laetitia_n perseverans_fw-la per_fw-la multos_fw-la dies_fw-la somnum_fw-la impedit_fw-la persevere_v pleasure_n may_v do_v the_o same_o by_o like_a reason_n that_o be_v too_o much_o 〈◊〉_d or_o ovation_n of_o the_o spirit_n sometime_o too_o large_a a_o do_v cause_n watch_v by_o over-actuating_a and_o exciting_a the_o spirit_n medicum_fw-la vini_fw-la generosi_fw-la &_o allium_fw-la say_v sanctorius_n conciliant_fw-la somnum_fw-la &_o perspirationem_fw-la si_fw-la vero_fw-la plus_fw-la justo_fw-la sumantur_fw-la utrumque_fw-la prohibent_fw-la perspirabile_fw-la tamen_fw-la in_o sudorem_fw-la convertunt_fw-la that_o be_v a_o little_a generous_a wine_n and_o garlic_n will_v cause_v sleep_n and_o perspiration_n but_o too_o much_o hinder_v both_o yet_o they_o convert_v the_o perspirable_a matter_n to_o a_o sweat_n which_o wine_n and_o garlick_n have_v the_o nature_n of_o opiate_n and_o the_o reason_n why_o they_o sweat_v be_v the_o quantity_n of_o the_o wine_n afford_v more_o moisture_n hypocrates_n say_v 23._o a_o dubious_a state_n between_o sleep_v and_o wake_v be_v cause_v when_o the_o relaxation_n upon_o the_o pleasure_n of_o opium_n incline_v to_o sleep_v but_o the_o irreâ—uiete_a ovation_n of_o the_o spirit_n by_o the_o pleasure_n and_o titillation_n will_v hardly_o suffer_v it_o yet_o high_o please_v and_o put_v they_o in_o a_o sweet_a agreeable_a condition_n chap._n xix_o the_o explication_n of_o the_o rare_a effect_n of_o opium_n in_o a_o moderate_a do_v 1._o it_o cause_v temporary_a pulse_n of_o the_o 〈◊〉_d and_o sometime_o of_o other_o part_n by_o its_o over_o relax_v the_o part_n and_o cause_v thereby_o a_o expansion_n of_o the_o elastic_a spirit_n which_o as_o be_v demonstrate_v weaken_v their_o motion_n 2._o falter_v of_o the_o tongue_n do_v as_o in_o relaxation_n by_o drunkenness_n proceed_v from_o the_o same_o cause_n 3._o looseness_n of_o the_o low_a jaw_n as_o you_o see_v in_o the_o drowsy_a and_o drunken_a people_n be_v from_o the_o same_o relaxation_n 4._o it_o sometime_o prevent_v sweat_n by_o cause_v a_o very_a liberal_a perspiration_n as_o be_v show_v for_o as_o sanctorius_n say_v who_o shall_v know_v it_o much_o insensible_a perspiration_n and_o sweat_n can_v consist_v especial_o in_o a_o temperate_a person_n who_o eat_v and_o drink_v moderate_o therefore_o if_o you_o keep_v a_o person_n that_o sweat_v much_o at_o night_n in_o a_o free_a perspiration_n all_o day_n by_o the_o help_n of_o a_o opiate_n you_o will_v much_o lessen_v or_o total_o prevent_v the_o sweat_n at_o night_n as_o in_o consumptive_a person_n etc._n etc._n 5._o it_o cause_v abortion_n by_o relax_v the_o neck_n of_o the_o womb_n which_o also_o the_o pleasure_n of_o coition_n sometime_o do_v for_o the_o like_a reason_n and_o will_v be_v much_o more_o apt_a to_o cause_v it_o if_o it_o continue_v long_o as_o that_o of_o opium_n do_v note_v the_o inconvenience_n of_o coition_n after_o impregnation_n this_o be_v the_o great_a cause_n that_o whore_n be_v not_o apt_a to_o bear_v child_n because_o frequency_n of_o pleasure_n do_v over-relax_a the_o collum_n 〈◊〉_d 6._o it_o prevent_v abortion_n when_o fear_n terror_n or_o any_o contract_a cause_n as_o grief_n grievous_a passion_n or_o sensation_n do_v threaten_v it_o by_o its_o take_n off_o the_o contraction_n and_o grievance_n that_o cause_v it_o 7_o intumescence_n of_o the_o lip_n be_v from_o their_o relaxation_n admit_v the_o blood_n and_o humour_n into_o they_o in_o a_o plentiful_a manner_n beside_o that_o their_o laxity_n and_o the_o inadvertency_n occasion_v by_o the_o divert_v pleasure_n or_o drowsiness_n that_o follow_v let_v the_o low_a lip_n hang_v down_o careless_o as_o be_v usual_a in_o such_o case_n may_v by_o expose_v much_o more_o of_o that_o lip_n which_o be_v most_o concern_v in_o this_o effect_n make_v it_o seem_v large_a as_o a_o hang_a lip_n do_v 8._o it_o may_v cure_v a_o dropsy_n as_o dr._n wâ—llis_n do_v instance_n 1._o by_o cause_v a_o free_a perspiration_n which_o be_v much_o want_v in_o those_o case_n 2._o by_o relax_v the_o pore_n and_o make_v way_n for_o the_o humour_n to_o 〈◊〉_d 3._o by_o cause_v much_o urine_n as_o cantharides_n millepedes_n &c_n &c_n do_v upon_o the_o account_n of_o their_o volatile-salt_n with_o which_o opium_n abound_v 9_o it_o cure_v stupor_n that_o proceed_v from_o contraction_n as_o by_o cold_a etc._n etc._n by_o relax_v all_o part_n 10._o it_o cause_v anxiety_n and_o distress_n by_o the_o rosin_n stick_v and_o teaze_v the_o stomach_n 11._o vomit_n and_o hiccough_n proceed_v from_o the_o same_o cause_n 12._o convulsion_n be_v cause_v by_o the_o same_o rosin_n while_o it_o continual_o urge_v the_o stomach_n to_o grievous_a vomit_n which_o at_o last_o draw_v other_o part_n as_o the_o stomach_n usual_o do_v when_o under_o great_a grievance_n into_o violent_a contraction_n or_o convulsion_n by_o consent_n to_o endeavour_v its_o assistance_n because_o the_o defensive_a contraction_n grow_v very_o high_a by_o the_o almost_o intolerable_a and_o tedious_a grievance_n at_o stomach_n cause_v a_o mighty_a compression_n of_o the_o springy_a animal_n spirit_n by_o which_o mean_v they_o grow_v very_o forcible_a irrequiete_a and_o violent_o springy_a under_o the_o urgency_n of_o a_o enormous_a compressure_n which_o cause_v such_o convulsive_a motion_n note_v that_o such_o a_o violent_a compression_n of_o the_o animal_n spirit_n into_o a_o great_a springiness_n be_v the_o cause_n of_o the_o strength_n of_o convulsive_a motion_n so_o that_o sometime_o a_o strong_a man_n can_v hardly_o hold_v a_o child_n limb_n in_o such_o case_n 13._o syncopes_fw-la leipothymy_n and_o faint_n follow_v when_o the_o sensitive_a soul_n be_v quite_o tire_v and_o overbear_v by_o the_o fatigue_n of_o such_o distress_n vomit_n and_o defensive_a contraction_n to_o reject_v and_o excuss_v the_o say_v adhere_v and_o teaze_v rosin_n yield_v itself_o to_o rest_n and_o let_v we_o go_v the_o reign_v of_o contraction_n as_o be_v fruitless_a and_o no_o long_o endurable_a whereupon_o all_o the_o sensile_a part_n be_v relax_v in_o the_o high_a degree_n they_o thereby_o grow_v unfit_a for_o sensation_n and_o the_o animal_n spirit_n expand_v as_o far_o as_o the_o atmospherical_a compressure_n permit_v they_o so_o that_o they_o grow_v incapable_a to_o convey_v impression_n by_o which_o mean_v sense_n fail_v and_o motion_n also_o for_o the_o same_o reason_n because_o the_o animal_n spirit_n loose_v their_o springy_a endeavour_n for_o want_n of_o a_o sufficient_a compression_n to_o render_v they_o flippant_a for_o the_o purpose_n which_o be_v the_o cause_n as_o in_o sleep_n that_o sense_n
the_o pleasure_n yet_o be_v neither_o discover_v for_o many_o thousand_o of_o year_n especial_o consider_v also_o that_o in_o the_o case_n of_o opium_n thousand_o of_o ingenious_a man_n have_v diligent_o inquire_v after_o the_o cause_n of_o its_o operation_n who_o make_v no_o far_a step_n in_o it_o then_o to_o state_n thing_n that_o have_v not_o as_o much_o as_o existence_n viz._n a_o cold_a quality_n and_o 〈◊〉_d fly_v from_o the_o stomach_n to_o the_o head_n to_o be_v the_o cause_n thereof_o therefore_o it_o be_v plain_a that_o neither_o be_v he_o that_o plant_n any_o thing_n neither_o he_o that_o water_v but_o god_n that_o give_v the_o increase_n of_o knowledge_n and_o of_o other_o thing_n to_o who_o be_v all_o glory_n chap._n xx._n the_o explication_n of_o the_o effect_n of_o the_o declination_n of_o the_o operation_n of_o opium_n in_o a_o moderate_a do_v 1._o a_o general_n return_v of_o all_o disease_n and_o disaster_n when_o the_o operation_n of_o opium_n be_v over_o because_o it_o do_v not_o as_o be_v show_v operate_v as_o a_o alterative_a but_o a_o please_a diverter_n of_o the_o sensitive_a soul_n for_o some_o time_n during_o which_o it_o cause_v a_o general_a relaxation_n of_o all_o the_o sensile_a part_n whereby_o the_o animal_n spirit_n be_v expanded_a grow_v unfit_a to_o convey_v impression_n smart_o which_o be_v requisite_a to_o cause_v a_o sense_n of_o pain_n etc._n etc._n as_o have_v be_v often_o say_v but_o it_o cure_v several_a distemper_n viz._n such_o as_o please_v and_o comfort_v the_o sensitive_a soul_n compose_v the_o spirit_n relaxation_n perspiration_n sweat_v etc._n etc._n can_v quite_o take_v away_o of_o which_o more_o particular_o when_o we_o come_v to_o speak_v of_o the_o use_n of_o opium_n in_o cure_n 2._o sweat_n happen_v in_o the_o declination_n of_o its_o operation_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v because_o that_o now_o all_o the_o parâ—s_a contract_n which_o by_o their_o relaxation_n suspend_v all_o humour_n during_o its_o operation_n do_v mechanical_o squeeze_v out_o the_o congest_a humour_n there_o be_v less_o room_n in_o the_o body_n as_o be_v say_v of_o sweat_n upon_o awake_v by_o the_o return_n of_o the_o vigilative_a contraction_n after_o relaxation_n during_o the_o sleep_n which_o be_v to_o be_v compare_v to_o the_o relaxation_n during_o the_o operation_n of_o opium_n and_o the_o return_v of_o the_o contraction_n when_o it_o be_v end_v beside_o that_o both_o upon_o the_o go_v off_o of_o the_o operation_n and_o awake_v the_o motion_n of_o the_o heart_n grow_v more_o vigorous_a as_o it_o do_v upon_o motion_n by_o the_o intentive_a contraction_n do_v more_o powerful_o propell_v the_o humour_n out_o at_o the_o pore_n as_o happen_v in_o sweat_n upon_o motion_n 3._o frequent_v make_v of_o water_n happen_v partly_o by_o the_o titillation_n of_o the_o volatile_a salt_n as_o by_o cantharides_n etc._n etc._n that_o be_v now_o separate_v from_o the_o blood_n partly_o by_o the_o contraction_n of_o the_o whole_a body_n squeese_v it_o out_o at_o the_o kidney_n as_o when_o people_n be_v cold_a they_o make_v more_o water_n for_o that_o reason_n 4._o a_o looseness_n may_v and_o do_v happen_v sometime_o from_o the_o like_a contraction_n squeese_v out_o the_o humour_n that_o be_v suspend_v during_o the_o relaxation_n by_o the_o opium_n which_o be_v common_a for_o such_o contraction_n to_o cause_n as_o by_o cold_a terror_n etc._n etc._n and_o because_o sensation_n grow_v more_o nice_a and_o irritable_a by_o the_o humour_n by_o reason_n of_o the_o contraction_n which_o be_v the_o more_o for_o the_o grievance_n of_o fail_v of_o the_o pleasure_n of_o opium_n therefore_o 5._o disease_n pain_n etc._n etc._n seem_v worse_o upon_o the_o return_n of_o the_o grievance_n because_o of_o the_o great_a ease_n they_o have_v during_o the_o operation_n of_o the_o opium_n contraria_fw-la inter_fw-la se_fw-la magis_fw-la elucescunt_fw-la and_o it_o be_v particular_o observe_v of_o pleasure_n that_o it_o leave_v man_n worse_o than_o it_o find_v they_o thus_o a_o man_n be_v worse_a more_o sad_a etc._n etc._n post_fw-la coitum_fw-la more_o melancholy_a after_o all_o sort_n of_o pleasure_n insomuch_o that_o it_o be_v grow_v to_o a_o proverb_n viz._n after_o merry_a come_v sorry_a or_o after_o mirth_n come_v sorrow_n as_o also_o minus_n gaudebis_fw-la minus_fw-la dolebis_fw-la therefore_o 6._o melaneholy_n do_v often_o if_o not_o always_o happen_v in_o some_o degree_n after_o its_o operation_n be_v end_v 1._o because_o of_o the_o return_n of_o the_o contraction_n or_o toil_n of_o the_o sensitive_a soul_n 2._o because_o as_o be_v say_v the_o sense_n of_o pleasure_n new_o lose_v aggravate_v the_o sorrow_n as_o have_v be_v show_v after_o coition_n etc._n etc._n 7._o the_o pulse_n be_v narrow_a because_o the_o contraction_n return_v with_o melancholy_a and_o return_v of_o disaster_n improve_v when_o that_o so_o happen_v as_o it_o general_o do_v 8._o itch_a of_o the_o skin_n happen_v about_o this_o time_n because_o that_o now_o the_o volatile_a salt_n which_o cause_v tuillation_n be_v arrive_v as_o far_o as_o the_o skin_n upon_o its_o march_n out_o of_o the_o body_n chap._n xxi_o the_o explication_n of_o the_o effect_n of_o opium_n in_o a_o excessive_a do_v the_o cause_n of_o most_o of_o these_o effect_n will_v be_v evident_a from_o the_o explication_n of_o the_o former_a because_o the_o difference_n be_v only_o in_o the_o quantity_n of_o the_o opium_n therefore_o i_o be_o often_o necessitate_v to_o speak_v much_o the_o same_o as_o i_o have_v do_v before_o you_o can_v expect_v any_o good_a effect_n from_o its_o excess_n any_o more_o than_o you_o have_v from_o wine_n though_o the_o best_a of_o cordial_n next_o to_o the_o sal._n volatile_a oleosum_fw-la of_o opium_n but_o rather_o less_o because_o opium_n be_v join_v to_o a_o pernicious_a rosin_n which_o you_o may_v be_v sure_o will_v be_v very_o grievous_a to_o the_o stomach_n in_o great_a quantity_n if_o it_o be_v so_o in_o little_a the_o evil_a effect_n in_o this_o case_n do_v main_o proceed_v either_o from_o too_o much_o relaxation_n as_o in_o drunkenness_n or_o from_o the_o rosin_n at_o stomach_n 1._o a_o heat_n at_o stomach_n be_v cause_v by_o the_o intense_a heat_n of_o the_o opium_n in_o a_o great_a quantity_n it_o be_v sensible_o a_o very_a hot_a thing_n 2._o the_o sense_n of_o weight_n at_o stomach_n be_v cause_v by_o the_o great_a relaxation_n that_o it_o cause_n which_o render_v the_o stomach_n proportionable_o weak_a and_o unable_a to_o endeavour_v its_o own_o relief_n so_o that_o the_o rosin_n etc._n etc._n lie_v heavy_a upon_o it_o thus_o we_o find_v a_o great_a heaviness_n at_o stomach_n when_o any_o thing_n grieve_v it_o that_o it_o can_v reject_v or_o discharge_v 3._o gaity_n of_o humour_n be_v cause_v at_o first_o as_o by_o the_o pleasure_n of_o a_o great_a quantity_n of_o wine_n by_o its_o please_a agreeableness_n to_o the_o membrane_n at_o stomach_n till_o the_o relaxation_n grow_v enormous_a as_o by_o a_o great_a do_v of_o wine_n sudden_o drink_v to_o which_o it_o be_v very_o like_a in_o all_o its_o effect_n except_o such_o as_o proceed_v from_o the_o rosin_n stick_v at_o stomach_n which_o wine_n have_v not_o 4._o sardonick_a laughter_n be_v cause_v as_o you_o see_v in_o drunken_a people_n when_o they_o be_v disable_v by_o the_o great_a relaxation_n that_o they_o can_v well_o express_v themselves_o by_o the_o fail_a tongue_n they_o endeavour_v it_o by_o a_o silly_a kind_n of_o feign_a or_o make_v laughter_n as_o they_o call_v it_o while_o the_o please_a titillation_n at_o stomach_n much_o incline_v they_o to_o mirth_n if_o they_o know_v how_o to_o manage_v and_o carry_v it_o on_o 5._o laxity_n and_o consequent_o debility_n of_o all_o part_n be_v cause_v by_o the_o extraordinary_a relaxation_n of_o they_o by_o a_o continual_a and_o permanent_a sense_n of_o pleasure_n which_o happen_v considerable_o in_o the_o momentary_a pleasure_n of_o venus_n much_o more_o in_o this_o continual_a and_o last_a pleasure_n when_o a_o great_a do_v make_v it_o intense_a as_o in_o drunkenness_n 6._o alienation_n of_o the_o mind_n be_v cause_v as_o in_o drunkenness_n by_o a_o over_o relaxation_n of_o the_o brain_n and_o its_o membrane_n 7._o loss_n of_o memory_n happen_v by_o the_o same_o mean_n as_o in_o drunkenness_n so_o 8._o darkness_n of_o eye_n be_v cause_v by_o a_o relaxation_n of_o the_o coat_n and_o membrane_n of_o the_o eye_n but_o main_o by_o the_o expansion_n of_o the_o animal_n spirit_n by_o that_o relaxation_n which_o as_o in_o sleep_n render_v they_o unfit_a to_o convey_v the_o impression_n of_o light_n etc._n etc._n 9_o laxity_n of_o the_o cornea_n be_v from_o the_o same_o relaxation_n 10._o appearance_n of_o various_a colour_n happen_v by_o as_o be_v say_v the_o unevenness_n of_o the_o cornea_n etc._n etc._n when_o so_o relax_v whereas_o when_o it_o be_v due_o
contract_v it_o be_v round_o even_o polite_a and_o true_o represent_v thing_n 11._o deadness_n of_o the_o eye_n to_o the_o view_n be_v as_o have_v be_v show_v from_o the_o laxity_n of_o the_o cornea_n which_o make_v it_o flag_n lie_v loose_a look_v dull_o and_o not_o due_o reflect_v a_o smart_n and_o brisk_a speck_n of_o light_n as_o it_o do_v when_o tense_n round_o and_o polite_a by_o its_o contraction_n on_o the_o contain_v humour_n which_o then_o due_o fill_v it_o 12._o falter_v of_o the_o tongue_n be_v from_o the_o same_o relaxation_n as_o in_o drunken_a person_n 13._o a_o sopor_fw-la be_v from_o the_o same_o relaxation_n over_o all_o the_o sensile_a part_n of_o the_o body_n by_o which_o mean_v sense_n and_o motion_n be_v diminish_v or_o lose_v by_o the_o expansion_n of_o the_o animal_n spirit_n which_o as_o have_v be_v say_v be_v not_o due_o compress_v become_v unfit_a for_o both_o at_o the_o same_o time_n 14._o a_o slow_a and_o wide_a pulse_n be_v from_o the_o same_o cause_n because_o the_o say_a relaxation_n permit_v the_o artery_n to_o widen_v and_o the_o animal_n spirit_n to_o expand_v and_o consequent_o render_v the_o motion_n of_o the_o heart_n slow_a which_o be_v the_o cause_n of_o the_o pulse_n 15._o a_o high_a colour_n or_o efflorescence_n of_o the_o skin_n have_v be_v explain_v 16._o looseness_n of_o the_o jaw_n and_o lip_n be_v from_o the_o same_o relaxation_n as_o be_v show_v and_o so_o be_v 17._o intumescence_n of_o the_o lip_n as_o have_v be_v show_v 18._o difficulty_n of_o breathe_v may_v be_v from_o two_o different_a cause_n either_o by_o the_o relaxation_n weaken_v the_o requisite_a motion_n for_o want_n of_o compressure_n of_o the_o animal_n spirit_n and_o by_o the_o flaccity_n of_o the_o part_n themselves_o or_o by_o a_o great_a grievance_n at_o stomach_n upon_o the_o account_n of_o the_o rosin_n stick_v to_o it_o and_o cause_v a_o convulsion_n of_o those_o part_n both_o which_o may_v happen_v 19_o fury_n and_o madness_n may_v also_o happen_v either_o by_o the_o exalt_a pleasure_n of_o its_o titillation_n as_o in_o drunkard_n who_o therefore_o scarce_o know_v what_o they_o do_v the_o mind_n be_v as_o be_v say_v alienate_v or_o it_o may_v happen_v as_o i_o have_v often_o know_v a_o kind_n of_o madness_n to_o be_v produce_v by_o a_o great_a grievance_n at_o stomach_n which_o may_v well_o be_v from_o the_o rosin_n grieve_v and_o teaze_v the_o nice_o sensile_a stomach_n they_o may_v be_v easy_o distinguish_v one_o viz._n that_o from_o the_o rosin_n at_o stomach_n be_v with_o great_a distress_n anxiety_n convulsion_n etc._n etc._n and_o the_o other_o without_o any_o 20._o venereal_a fury_n proceed_v from_o the_o high_a titillation_n of_o the_o venereal_a membrane_n by_o the_o volatile_a salt_n of_o so_o much_o opium_n as_o if_o cantharides_n bee_n &c_n &c_n be_v take_v internal_o but_o that_o these_o can_v so_o agreeable_o titillate_v those_o part_n as_o opium_n do_v who_o volatile_a particle_n be_v render_v more_o please_a by_o oily_a one_o and_o therefore_o much_o of_o the_o nature_n of_o semen_n virile_a 21._o priapism_n be_v cause_v by_o the_o same_o continual_a titillation_n 22._o violent_a itch_n of_o the_o skin_n be_v cause_v by_o the_o same_o tickle_a volatile_a particle_n in_o great_a abundance_n proportionable_a to_o the_o excessive_a do_v 23._o nauseas_fw-la be_v cause_v by_o the_o rosin_n stick_v at_o and_o solicit_v the_o stomach_n to_o vomit_v 24._o swimmings_n in_o the_o head_n be_v by_o conseâ—it_n because_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o be_v observe_v in_o many_o case_n from_o a_o grieve_a stomach_n upon_o a_o tendency_n to_o vomit_v as_o when_o it_o be_v overload_v with_o wine_n or_o indigestible_a victual_n or_o when_o person_n be_v sea_n or_o coach-sick_a etc._n etc._n for_o it_o be_v not_o in_o these_o last_o case_n because_o the_o brain_n be_v offend_v as_o people_n imagine_v that_o they_o be_v sick_a or_o vomit_n but_o the_o swim_v in_o the_o head_n and_o offence_n of_o the_o brain_n happen_v because_o the_o stomach_n be_v offend_v by_o the_o motion_n of_o the_o coach_n or_o ship_n by_o reason_n of_o its_o most_o exquisite_a sensation_n which_o the_o effluvias_fw-la of_o a_o cat_n pestiferous_a particle_n and_o commotion_n cause_v by_o mear_v passion_n can_v and_o do_v offend_v as_o be_v say_v so_o as_o to_o cause_v vomit_n anxiety_n etc._n etc._n much_o more_o than_o may_v the_o motion_n of_o a_o ship_n or_o coach_n do_v it_o i_o shall_v not_o here_o enter_v into_o controversy_n with_o those_o that_o assert_v that_o it_o be_v the_o head_n be_v first_o offend_v in_o a_o coach_n or_o ship_n it_o be_v sufficient_a for_o my_o purpose_n that_o grievance_n at_o stomach_n do_v common_o cause_n swimmings_n in_o the_o head_n for_o take_v off_o those_o grievance_n cure_v they_o as_o eat_v when_o it_o be_v from_o the_o grievance_n of_o hunger_n or_o wind_n at_o stomach_n and_o discharge_v the_o stomach_n of_o a_o great_a load_n of_o wine_n ale_z or_o indigestible_a matter_n when_o such_o thing_n cause_v it_o do_v cure_v such_o swimming_n in_o the_o head_n the_o way_n how_o grievance_n at_o stomach_n do_v cause_n those_o swimming_n be_v by_o cause_v a_o contraction_n as_o all_o grievance_n do_v but_o especial_o those_o at_o stomach_n of_o the_o membrane_n of_o the_o brain_n as_o it_o do_v of_o all_o other_o but_o main_o of_o these_o because_o very_o sensile_a by_o which_o mean_v the_o animal_n spirit_n be_v compress_v grow_v more_o irrequiete_a and_o skip_a up_o and_o down_o and_o the_o compression_n not_o be_v continual_o alike_o in_o general_n or_o the_o artery_n afford_v a_o uneven_a and_o forcible_a supply_n of_o they_o or_o fume_n from_o the_o blood_n by_o the_o compression_n nor_o affect_v all_o part_n of_o the_o brain_n with_o equal_a force_n because_o the_o pleasure_n endeavour_n to_o relax_v etc._n etc._n there_o must_v thence_o arise_v eddy_n vortices_fw-la or_o whirl_v thereof_o which_o cause_n swimmings_n vertigo_n &c._n &c._n according_a as_o they_o happen_v to_o be_v move_v that_o they_o happen_v from_o such_o contraction_n be_v manifest_a 1._o because_o the_o grievance_n at_o stomach_n can_v add_v nothing_o else_o to_o the_o brain_n or_o its_o membrane_n 2._o because_o they_o be_v take_v off_o by_o please_v the_o stomach_n and_o consequent_o by_o relaxation_n as_o by_o a_o glass_n of_o wine_n victual_n a_o opiate_n that_o be_v not_o resinous_a etc._n etc._n it_o be_v here_o well_o worth_a your_o notice_n that_o all_o consent_n of_o part_n a_o thing_n much_o admire_v be_v only_o by_o contraction_n or_o relaxation_n which_o sudden_o affect_v the_o whole_a systeme_n of_o the_o nerve_n and_o membrane_n 25._o vertigo_n be_v from_o the_o same_o cause_n 26._o vomit_n be_v cause_v as_o be_v say_v by_o the_o great_a grievance_n of_o the_o acrimonious_a rosin_n stick_v to_o the_o coat_n of_o the_o stomach_n 27._o hiccongh_n be_v from_o the_o same_o cause_n which_o happen_v upon_o the_o decay_n of_o power_n vigorous_o to_o vomit_v dwindle_v into_o those_o fruitless_a convulsive_a subsultory_n jerâ—_n or_o half_a endeavour_n 28._o distress_n and_o anxiety_n must_v necessary_o attend_v such_o a_o grievous_a sensation_n and_o desection_n of_o nature_n endeavour_v as_o be_v overbear_v and_o disable_v to_o work_v for_o itself_o 29._o a_o turbulent_a pulse_n must_v be_v a_o effect_n of_o the_o forego_n tumult_n 30._o convulsion_n happen_v as_o be_v show_v by_o the_o enormous_a compression_n of_o the_o animal_n spirit_n by_o reason_n of_o the_o violent_a contraction_n upon_o the_o great_a grievance_n by_o the_o rosin_n at_o stomach_n which_o cause_v they_o to_o skip_v and_o fling_v up_o and_o down_o very_o forcible_o under_o the_o squeeze_v of_o the_o compression_n and_o possible_o skirmish_v under_o the_o vicissitude_n of_o it_o and_o relaxation_n 31._o faint_n and_o leipothymy_n be_v cause_v as_o have_v be_v explain_v by_o the_o sensitive_a soul_n be_v overtired_n by_o the_o fatigue_n of_o defensive_a contraction_n and_o yield_v himself_o to_o rest_n from_o all_o contraction_n as_o the_o last_o relief_n etc._n etc._n whereupon_o sense_n and_o motion_n do_v fail_v for_o want_v of_o compression_n to_o render_v the_o spirit_n springy_a active_a and_o fit_a for_o the_o purpose_n 32._o cold_a breath_n be_v but_o a_o necessary_a consequence_n of_o the_o loss_n of_o motion_n and_o therefore_o of_o heat_n by_o such_o leipothymy_n and_o faint_n 33._o death_n be_v cause_v two_o manner_n of_o way_n that_o be_v either_o by_o a_o utter_a expense_n of_o spirit_n and_o thereupon_o a_o dereliction_n or_o extinction_n of_o the_o sensitive_a soul_n by_o reason_n of_o those_o distress_n and_o fatigue_n upon_o the_o account_n of_o the_o invincible_a rosin_n or_o by_o too_o much_o relaxation_n disable_n all_o the_o motion_n of_o the_o body_n as_o in_o such_o as_o die_v be_v dead_a drink_v
which_o look_v not_o unlike_o a_o apoplexy_n make_v author_n say_v that_o opium_n cause_v apoplexy_n such_o as_o escape_v death_n do_v so_o general_o by_o 34._o plentiful_a purge_v which_o be_v occasion_v by_o a_o great_a quantity_n of_o the_o rosin_n of_o opium_n meet_v a_o strong_a digestion_n and_o fix_a salt_n as_o have_v beeâ—_n say_v 35._o sweat_v that_o smell_n of_o the_o opium_n be_v cause_v 1._o by_o the_o openness_n of_o the_o pore_n by_o relaxation_n 2._o by_o plenty_n or_o at_o least_o sufficiency_n of_o moisture_n for_o that_o end_n for_o otherwise_o as_o be_v show_v it_o will_v be_v only_o insensible_a perspiration_n 3._o by_o the_o great_a quantity_n of_o volatile_a salt_n attenuate_v the_o humour_n 4._o by_o the_o strict_a intimate_a and_o even_o indissoluble_a specific_a union_n or_o combination_n of_o the_o volatile_a salt_n and_o oily_a part_n which_o make_v it_o hold_v its_o specific_a smell_n to_o the_o last_o 36._o violent_a itch_n in_o the_o skin_n must_v of_o necessity_n follow_v a_o great_a quantity_n of_o opium_n since_o it_o cause_v such_o itch_n as_o be_v show_v in_o a_o small_a quantity_n by_o the_o titillation_n of_o its_o volatile_a salt_n note_v that_o these_o effect_n do_v not_o all_o happen_v to_o all_o man_n that_o take_v it_o in_o a_o excessive_a do_v but_o some_o to_o one_o and_o some_o to_o other_o as_o be_v intimate_v in_o chap._n 5._o according_a as_o they_o be_v more_o or_o less_o trouble_v with_o the_o rosin_n quantity_n relaxation_n etc._n etc._n chap._n xxii_o the_o explication_n of_o the_o effect_n of_o a_o long_a and_o lavish_a use_n of_o opium_n as_o a_o excessive_a do_v of_o opium_n be_v intemperance_n for_o one_o time_n so_o a_o long_a and_o lavish_a use_n of_o it_o be_v a_o habitual_a intemperance_n for_o a_o long_a time_n therefore_o if_o you_o can_v not_o rational_o expect_v good_a effâ—s_n in_o that_o case_n any_o more_o than_o from_o the_o best_a wine_n take_v sudden_o in_o a_o vast_a quantity_n it_o follow_v that_o you_o can_v expect_v good_a effect_n from_o a_o habitual_a intemperate_a take_v of_o it_o any_o more_o than_o from_o a_o long_a and_o lavish_a drink_v of_o wine_n though_o both_o be_v excellent_o good_a in_o their_o kind_a but_o that_o the_o opium_n have_v the_o pernicious_a resinous_a part_n join_v with_o it_o there_o be_v nothing_o so_o good_a whereof_o a_o intemperate_a use_n be_v not_o mischievous_a god_n have_v so_o order_v it_o to_o deter_v from_o and_o punish_v intemperance_n and_o the_o abuse_n of_o his_o creature_n therefore_o ill_a effect_n be_v not_o always_o to_o be_v impute_v to_o the_o viciousness_n of_o the_o thing_n use_v but_o frequent_o of_o the_o person_n that_o imprudent_o use_v they_o 1._o relaxation_n and_o debility_n of_o all_o part_n be_v contract_v by_o the_o habitual_a over-relaxing_a thereof_o by_o the_o lavish_a use_n of_o opium_n 2._o a_o inhability_n of_o do_v any_o thing_n without_o it_o be_v contract_v by_o the_o habitual_a pleasure_n comfort_n promptitude_n and_o euphory_n it_o cause_v when_o take_v without_o which_o the_o sensitive_a soul_n become_v lazy_a listless_a and_o averse_a to_o all_o action_n it_o be_v as_o iâ—_n a_o man_n use_v to_o dance_n to_o excellent_a music_n be_v require_v to_o do_v it_o without_o any_o music_n at_o all_o nor_o as_o much_o as_o thought_n of_o it_o or_o mumble_v it_o within_o himself_o or_o that_o one_o who_o drink_v nothing_o but_o wine_n and_o eat_v the_o best_a shall_v be_v sudden_o deny_v both_o and_o force_v to_o live_v upon_o bread_n and_o water_n or_o that_o such_o as_o always_o take_v tobacco_n at_o their_o study_n shall_v be_v sudden_o debar_v thereof_o and_o require_v to_o study_v without_o it_o how_o very_o listless_a will_v a_o man_n be_v in_o such_o case_n though_o hardly_o any_o of_o the_o comparison_n come_v up_o to_o that_o of_o opium_n because_o of_o the_o charm_a pleasure_n mighty_a euphory_n and_o promptitude_n that_o it_o cause_n it_o be_v as_o if_o one_o be_v support_v and_o whole_o depend_v upon_o cordial_n and_o sudden_o deny_v they_o etc._n etc._n 3._o a_o inhability_n of_o get_v up_o in_o the_o morning_n till_o it_o be_v take_v and_o begin_v to_o operate_v proceed_v from_o the_o same_o cause_n a_o mechanical_a reason_n may_v be_v expect_v here_o also_o as_o to_o these_o matter_n but_o it_o will_v hardly_o bear_v it_o any_o more_o than_o how_o the_o will_n or_o appetite_n cause_v the_o first_o impulse_n towards_o voluntary_a moti_fw-la n_o all_o that_o can_v be_v say_v be_v that_o without_o the_o opium_n the_o sensitive_a soul_n be_v when_o he_o do_v any_o thing_n to_o act_v under_o the_o toil_n and_o difficulty_n of_o a_o full_a vigilative_a contraction_n as_o be_v awake_a intentive_a contraction_n as_o act_v and_o defensive_a contraction_n as_o be_v grieve_v when_o the_o operation_n of_o opium_n be_v over_o as_o after_o veneral_a pleasure_n etc._n etc._n so_o that_o now_o he_o labour_v under_o the_o great_a disadvantage_n and_o drudgery_n of_o all_o the_o three_o contraction_n whereas_o by_o the_o pleasure_n fine_a titillation_n of_o opium_n and_o relaxation_n consequential_a thereunto_o he_o be_v ease_v of_o all_o the_o defensive_a contraction_n which_o be_v the_o most_o grievous_a and_o in_o great_a measure_n of_o the_o vigilative_a as_o have_v be_v show_v which_o make_v work_v journey_a etc._n etc._n very_o easy_a to_o he_o therefore_o it_o be_v as_o if_o one_o that_o delight_v in_o music_n dance_v to_o charm_a melody_n in_o belove_a company_n with_o please_a refection_n of_o wine_n etc._n etc._n and_o in_o the_o other_o case_n as_o if_o one_o labour_v in_o grief_n or_o pain_n now_o suppose_v that_o one_o use_v never_o to_o act_n or_o work_n without_o such_o mighty_a pleasant_a advantage_n and_o cause_n of_o euphory_n be_v require_v to_o act_v under_o the_o pressure_n of_o the_o three_o contraction_n or_o in_o grief_n or_o pain_n how_o listless_a will_v he_o be_v to_o act_n work_n get_v up_o etc._n etc._n 4._o a_o dull_a moapish_a and_o heavy_a disposition_n must_v be_v the_o effect_n unless_o it_o be_v while_o they_o please_v comfort_n and_o enliven_v themselves_o by_o the_o opium_n because_o their_o brain_n be_v habitual_o over_o relax_v which_o be_v the_o very_a case_n of_o old_a drunkard_n who_o have_v as_o it_o be_v say_v drink_v away_o their_o part_n by_o such_o a_o habitual_a relaxation_n of_o the_o brain_n which_o overmuch_o sleep_v cause_n also_o upon_o the_o account_n of_o the_o like_a relaxation_n therefore_o they_o must_v be_v moapish_a till_o the_o please_a titillation_n of_o opium_n enlivens_fw-la they_o 5._o diminution_n of_o appetite_n be_v cause_v by_o a_o habitual_a relaxation_n of_o the_o stomach_n take_v away_o its_o sensation_n and_o suspend_v the_o menstruum_fw-la from_o flow_v to_o it_o as_o free_o as_o it_o shall_v and_o will_v if_o there_o be_v a_o due_a contraction_n to_o squeeze_v it_o out_o 6._o weakness_n of_o digestion_n happen_v from_o the_o same_o cause_n 7._o dropsy_n be_v cause_v by_o the_o relaxation_n weaken_v the_o part_n and_o make_v they_o thereby_o susceptible_a of_o humour_n as_o also_o by_o diminution_n of_o appetite_n and_o digestion_n as_o in_o old_a drunkard_n 8._o decay_n of_o part_n or_o wit_n happen_v from_o habitual_a relaxation_n of_o the_o brain_n and_o its_o membrane_n as_o in_o old_a drunkard_n 9_o weakness_n of_o memory_n proceed_v from_o the_o same_o cause_n as_o in_o old_a drunkard_n 10._o stoop_v in_o the_o back_n be_v cause_v by_o the_o habitual_a relaxation_n of_o the_o part_n which_o weaken_v and_o cause_v they_o to_o comply_v with_o our_o tendency_n and_o use_v of_o bend_v forward_o and_o yield_v to_o the_o great_a weight_n that_o be_v general_o speak_v on_o the_o foreside_n of_o the_o backbone_n or_o perpendicular_a so_o that_o stoop_v must_v gradual_o follow_v those_o conspire_a cause_n as_o it_o do_v in_o habitual_a drunkard_n who_o part_n be_v relax_v 11._o early_o decrepiteness_n must_v proceed_v from_o the_o aforesaid_a relaxation_n spoil_v the_o tone_n of_o part_n and_o cause_v want_n of_o appetite_n digestion_n etc._n etc._n in_o the_o manner_n before_o show_v 12._o shortness_n of_o life_n must_v be_v the_o effect_n of_o the_o same_o cause_n 13._o acrimony_n of_o blood_n proceed_v from_o the_o abundance_n of_o acrimonious_a volatile_a salt_n take_v in_o the_o opium_n wherein_o it_o be_v much_o more_o acrimonious_a than_o our_o natural_a volatile_a salt_n and_o in_o great_a quantity_n proportionable_o therefore_o it_o can_v be_v no_o wonder_n that_o 14._o it_o excite_v inclination_n to_o venery_n by_o that_o acrimonious_a salt_n which_o be_v analogous_a to_o that_o of_o cantharides_n aunt_n bee_n etc._n etc._n 15._o frequent_a inclination_n to_o make_v water_n be_v also_o a_o know_a and_o common_a effect_n of_o such_o a_o salt_n by_o its_o irritate_v and_o solicit_v the_o bladder_n etc._n etc._n 16._o priapism_n
and_o frequent_a erection_n be_v and_o must_v be_v from_o the_o same_o cause_n 17._o nocturnal_a pollution_n be_v necessary_a consequence_n of_o the_o relaxation_n and_o the_o titillation_n cause_v by_o those_o volatile_a salt_n as_o be_v say_v chap._n xxiii_o the_o explication_n of_o the_o effect_n of_o leave_v off_o opium_n after_o a_o long_a and_o lavish_a use_v thereof_o i._o great_a and_o even_o intolerable_a distress_n anxiety_n and_o depression_n of_o spirit_n do_v happen_v 1._o because_o the_o sensitive_a soul_n who_o be_v so_o much_o comfort_v divert_v and_o support_v by_o the_o habitual_a and_o dear_o belove_a pleasure_n that_o opium_n cause_n be_v sudden_o deprive_v thereof_o by_o which_o it_o be_v main_o sustain_v be_v exceed_o disappoint_v and_o cast_v down_o 2._o because_o he_o now_o labour_v under_o the_o sore_a burden_n of_o the_o three_o contraction_n so_o that_o every_o thing_n seem_v and_o be_v real_o more_o grievous_a â—o_o he_o for_o now_o it_o act_v as_o one_o in_o pain_n or_o grief_n and_o every_o thing_n affect_v he_o more_o smart_o proportionable_a to_o the_o compression_n cause_v thereby_o of_o the_o animal_n spirit_n unless_o he_o return_v to_o the_o pleasure_n of_o opium_n which_o elevate_v it_o again_o or_o use_v generous_a wine_n as_o its_o substitute_n though_o it_o do_v not_o equal_v it_o either_o in_o the_o intenseness_n or_o duration_n of_o the_o pleasure_n unless_o repeat_v as_o i_o have_v some_o where_o direct_v once_o in_o half_a a_o hour_n or_o a_o hour_n in_o a_o moderate_a manner_n which_o cause_v a_o continuance_n of_o the_o pleasure_n though_o it_o can_v equal_v the_o intenseness_n of_o that_o of_o opium_n which_o therefore_o have_v the_o great_a effect_n ii_o a_o return_n of_o all_o disease_n pain_n and_o disaster_n must_v happen_v general_o because_o the_o opium_n take_v they_o off_o by_o a_o bare_a diversion_n of_o the_o sense_n thereof_o by_o pleasure_n iii_o dangerous_a looseness_n happen_v sometime_o because_o the_o sensation_n grow_v more_o grievous_a for_o as_o the_o pleasant_a sensation_n cause_v by_o opium_n take_v away_o the_o perception_n of_o the_o irritation_n of_o humour_n so_o the_o grievance_n of_o lose_v that_o pleasure_n cause_v contraction_n make_v all_o sensation_n smart_a and_o consequent_o more_o irritate_v so_o that_o the_o humour_n have_v thereby_o more_o of_o the_o effect_n of_o purger_n which_o operate_v as_o all_o agree_v by_o irritation_n beside_o that_o the_o humour_n before_o detain_v and_o suspend_v by_o relaxation_n as_o in_o sleep_n be_v now_o therefore_o pour_v down_o in_o great_a quantity_n by_o the_o advance_a contraction_n squeese_v they_o out_o as_o the_o return_n of_o the_o vigilative_a contraction_n after_o sleep_n cause_n man_n to_o be_v more_o apt_a to_o go_v to_o stool_n upon_o awake_v or_o get_v up_o in_o the_o morning_n which_o may_v be_v well_o compare_v in_o some_o measure_n to_o purge_v after_o leave_v off_o the_o use_n of_o opium_n since_o it_o relax_n as_o sleep_n do_v and_o that_o for_o a_o much_o long_a time_n by_o a_o continue_a use_n thereof_o iv_o death_n common_o follow_v for_o all_o the_o reason_n aforesaid_a especial_o the_o great_a and_o intolerable_a distress_n of_o soul_n that_o they_o be_v under_o unless_o opium_n be_v use_v which_o soon_o set_v they_o right_o or_o wine_n its_o substitute_n so_o frequent_o use_v as_o to_o continue_v its_o cordial_a pleasure_n at_o stomach_n nothing_o now_o remain_v but_o to_o take_v a_o short_a review_n to_o see_v whether_o i_o have_v explain_v all_o the_o amaze_a contradiction_n that_o seem_v to_o be_v in_o the_o effect_n of_o opium_n for_o though_o it_o be_v real_o do_v yet_o may_v it_o not_o so_o well_o appear_v as_o when_o set_v one_o against_o the_o other_o it_o will_v be_v tautology_n to_o repeat_v all_o the_o reason_n therefore_o i_o shall_v only_o mention_v they_o in_o the_o close_a order_n i_o at_o first_o enumerate_v they_o that_o you_o may_v see_v that_o they_o be_v all_o explicate_v in_o the_o former_a discourse_n you_o may_v well_o remember_v that_o i_o have_v show_v 1._o how_o it_o cause_v sleep_v and_o watch_v in_o divers_a person_n 2._o how_o it_o cause_v and_o prevent_v sweat_n 3._o how_o it_o relax_n and_o stop_n looseness_n even_o by_o relax_v 4._o how_o it_o stop_v flux_n and_o promote_v sweat_v and_o perspiration_n 5._o how_o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v it_o 6._o how_o it_o cause_v stupidity_n if_o you_o sit_v or_o lie_v still_o otherwise_o promptitude_n in_o business_n 7._o how_o it_o cause_v cloudiness_n and_o serenity_n that_o if_o one_o lie_v still_o and_o doze_n this_o if_o he_o keep_v in_o action_n that_o by_o a_o excessive_a and_o lavish_a use_v thereof_o which_o cause_v moapishness_n this_o by_o a_o temperate_a occasional_a take_v thereof_o especial_o in_o the_o morning_n upon_o journey_n etc._n etc._n 8._o how_o it_o excite_v the_o spirit_n yet_o quiet_v and_o compose_v they_o in_o hysterick_n fit_v diary_n fever_n from_o pain_n commotion_n etc._n etc._n 9_o how_o that_o it_o be_v very_o hot_a and_o take_v of_o fever_n 10._o how_o though_o it_o be_v hot_a and_o bitter_a yet_o it_o lessen_v appetite_n and_o hunger_n which_o be_v a_o grievous_a sensation_n by_o cause_v a_o pleasant_a one_o 11._o how_o it_o sometime_o stop_v urine_n by_o relax_v the_o bladder_n suspending_a humour_n etc._n etc._n and_o promote_v it_o by_o its_o tickle_a volatile_a salt_n as_o cantharides_n bee_n aunt_n etc._n etc._n do_v 12._o how_o it_o relax_n and_o thereby_o weaken_v as_o in_o sleep_n etc._n etc._n yet_o enable_v to_o perform_v labour_n journey_n etc._n etc._n with_o great_a euphory_n by_o divertive_a pleasure_n 13._o how_o it_o cause_v and_o prevent_v abortion_n that_o by_o over-relaxing_a this_o by_o allay_a pain_n terror_n etc._n etc._n that_o may_v cause_v it_o 14._o how_o it_o stop_v vomit_v by_o take_v off_o irritation_n etc._n etc._n and_o cause_v it_o by_o the_o adherence_n of_o its_o indigestible_a and_o viscid_a rosin_n 15._o how_o it_o stop_v purge_v and_o sometime_o cause_v it_o by_o the_o dissolution_n of_o its_o rosin_n by_o a_o strong_a digestion_n fix_a salt_n etc._n etc._n when_o its_o quantity_n be_v considerable_a which_o make_v it_o happen_v but_o rare_o 16._o how_o though_o acrimonious_a it_o take_v away_o the_o sense_n of_o acrimony_n 17._o how_o it_o cause_v madness_n and_o cure_v it_o by_o compose_v the_o spirit_n etc._n etc._n 18._o how_o it_o cause_v palsy_n by_o relax_v the_o part_n and_o make_v they_o susceptible_a of_o humour_n cause_v ill_a digestion_n etc._n etc._n and_o may_v cure_v they_o as_o dr._n willis_n give_v a_o instance_n by_o open_v the_o pore_n 19_o how_o it_o cause_v palsy_n and_o cure_n stupor_n etc._n etc._n that_o proceed_v from_o cold_a and_o contract_n cause_n 20._o how_o it_o cause_v dryness_n in_o the_o mouth_n yet_o by_o take_v off_o fever_n often_o cure_v it_o 21._o how_o it_o take_v off_o hiccough_n and_o cause_v they_o as_o it_o do_v vomit_v and_o for_o the_o same_o cause_n 22._o how_o it_o stanch_v blood_n by_o quiet_v its_o motion_n yet_o promote_v the_o menses_fw-la and_o lochia_n by_o relax_v open_v and_o widen_v the_o vessel_n and_o pore_n 23._o how_o it_o stop_v critical_a motion_n that_o depend_v upon_o irritation_n and_o contraction_n and_o promote_v such_o as_o depend_v upon_o open_v the_o pore_n 24._o how_o it_o revive_v people_n that_o be_v at_o the_o point_n of_o death_n for_o want_n of_o opium_n or_o by_o violent_a contraction_n and_o convulsion_n and_o be_v fatal_a to_o other_o weak_a person_n 25._o how_o it_o cause_v convulsion_n by_o its_o grieve_v rosin_n and_o cure_v they_o by_o quiet_v and_o compose_v the_o spirit_n by_o please_v they_o 26._o how_o it_o cause_v contraction_n by_o the_o grievous_a sensation_n that_o its_o rosin_n cause_n and_o relaxation_n by_o the_o pleasant_a sensation_n that_o its_o salvolatile_a oleosum_fw-la cause_n by_o that_o it_o cause_v many_o ill_a effect_n not_o here_o name_v and_o by_o this_o it_o cure_v they_o for_o how_o can_v such_o contrary_a cause_n according_a as_o one_o or_o the_o other_o prevail_v not_o cause_v contrary_a and_o seem_o contradictory_n effect_n at_o divers_a time_n and_o in_o divers_a person_n 27._o how_o it_o relax_n yet_o cause_v the_o tension_n rigidity_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n by_o its_o titillation_n thus_o have_v you_o all_o even_o the_o most_o mysterious_a and_o seem_o contradictory_n effect_n of_o opium_n explain_v and_o reconcile_v and_o that_o so_o easy_o that_o if_o there_o be_v no_o other_o proof_n of_o the_o truth_n of_o my_o foundation_n it_o be_v sufficient_a to_o convince_v any_o man_n of_o its_o validity_n consider_v the_o vastness_n of_o the_o number_n and_o perplexity_n of_o the_o nature_n of_o those_o effect_n that_o be_v all_o with_o such_o facility_n explain_v be_v able_a even_o
the_o first_o symptom_n of_o a_o nausea_n vomit_v etc._n etc._n be_v most_o to_o be_v depend_v upon_o for_o it_o may_v happen_v sometime_o as_o after_o a_o great_a do_v that_o the_o rosin_n may_v stick_v etc._n etc._n and_o the_o relaxation_n be_v excessive_a also_o second_o when_o you_o be_v satisfy_v that_o it_o be_v the_o rosin_n at_o stomach_n that_o cause_v the_o mischief_n and_o not_o bare_a relaxation_n you_o be_v not_o to_o promote_v or_o stop_v the_o vomit_n lest_o in_o the_o first_o case_n you_o torment_n and_o endanger_v the_o person_n to_o no_o purpose_n for_o the_o rosin_n do_v general_o if_o not_o always_o stick_v too_o fast_o and_o too_o little_a in_o bulk_n to_o be_v shake_v off_o by_o vomit_v or_o the_o contraction_n of_o the_o stomach_n as_o appear_v by_o the_o tidious_a vomit_n that_o happen_v thereupon_o and_o the_o nature_n of_o the_o thing_n so_o that_o i_o believe_v it_o be_v seldom_o or_o never_o carry_v off_o that_o way_n and_o that_o when_o people_n be_v at_o last_o relieve_v it_o be_v by_o a_o gradual_a waste_n dissolution_n or_o digestion_n of_o the_o rosin_n as_o in_o great_a measure_n appear_v also_o by_o its_o purge_v some_o person_n after_o vomit_v and_o a_o long_a time_n after_o it_o be_v take_v in_o a_o considerable_a quantity_n nor_o be_v you_o to_o stop_v the_o vomit_v as_o not_o know_v what_o nature_n may_v advantage_n herself_o thereby_o but_o indeed_o it_o be_v more_o than_o you_o can_v do_v general_o speak_v if_o not_o always_o while_o the_o rosin_n teaze_v urge_v and_o sting_v the_o stomach_n it_o evident_o follow_v that_o the_o cure_n must_v consist_v in_o the_o dissolution_n of_o the_o rosin_n for_o this_o purpose_n you_o have_v four_o effectual_a dissolver_n of_o the_o rosin_n as_o you_o may_v observe_v from_o the_o chapter_n of_o the_o preparation_n of_o opium_n that_o may_v be_v use_v with_o safety_n in_o a_o moderate_a do_v 1._o lixivial_a salt_n whereof_o the_o best_a be_v salt_n of_o tartar_n 2._o sulphureous_a spirit_n whereof_o the_o best_a be_v high_a rectify_a spirit_n of_o wine_n 3._o the_o yolk_n of_o egg_n whereof_o the_o best_a be_v the_o yolk_n of_o a_o rear_n new_o lay_v egg._n 4._o white_a soap_n or_o rather_o the_o sapo_n tartareus_fw-la with_o these_o judicious_o use_v you_o may_v by_o god_n blessing_n relieve_v and_o cure_v the_o person_n grieve_v with_o the_o rosin_n or_o noxious_a part_n of_o opium_n 1._o give_v with_o all_o possible_a speed_n one_o scruple_n of_o salt_n of_o tartar_n in_o a_o spoonful_n or_o two_o of_o brandy_n or_o some_o other_o hot_a cordial_a spirit_n if_o spirit_n of_o wine_n be_v too_o hot_a place_v the_o person_n in_o the_o very_a same_o posture_n that_o he_o be_v in_o when_o he_o take_v the_o opiate_n that_o it_o may_v fall_v direct_o upon_o its_o rosin_n which_o most_o probable_o stick_v where_o the_o opiate_n first_o fall_v upon_o the_o coat_n of_o the_o stomach_n then_o stay_v for_o a_o minute_n or_o two_o and_o give_v a_o spoonful_n or_o two_o of_o the_o brandy_n or_o cordial_n with_o if_o need_v be_v the_o salt_n of_o tartar_n in_o it_o if_o you_o find_v cause_n either_o because_o the_o first_o dose_n be_v vomit_v or_o that_o the_o quantity_n of_o the_o rosin_n be_v great_a or_o that_o the_o person_n grow_v worse_a you_o may_v often_o repeat_v it_o for_o we_o must_v not_o be_v spare_v in_o safe_a thing_n in_o dangerous_a case_n i_o think_v it_o may_v well_o be_v repeat_v after_o every_o vomit_v toties_fw-la quoties_fw-la i_o have_v a_o great_a opinion_n of_o the_o yolk_n of_o a_o egg_n in_o these_o case_n not_o only_o because_o it_o do_v as_o the_o other_o thing_n mix_v with_o the_o rosin_n but_o because_o be_v of_o a_o good_a consistence_n it_o stick_v to_o it_o and_o fasten_v upon_o it_o the_o better_o and_o be_v not_o so_o clear_o shake_v from_o it_o by_o every_o vomit_n as_o liquid_n be_v therefore_o i_o think_v it_o very_o useful_a to_o be_v give_v now_o and_o then_o immediate_o after_o vomit_v however_o let_v no_o other_o food_n be_v give_v but_o it_o and_o be_v sure_a to_o use_v it_o when_o you_o have_v not_o the_o aforesaid_a thing_n i_o believe_v it_o will_v be_v find_v by_o experience_n which_o be_v yet_o much_o want_v because_o it_o have_v not_o be_v use_v to_o be_v the_o very_o best_a help_n in_o these_o case_n for_o the_o aforesaid_a reason_n and_o because_o its_o fine_a oiliness_n will_v correct_v the_o volatile_a salt_n of_o opium_n i_o can_v imagine_v but_o white_a soap_n or_o rather_o the_o sapo_n tartareus_fw-la if_o you_o have_v it_o by_o you_o may_v be_v of_o very_o good_a use_n to_o dissolve_v and_o carry_v off_o the_o rosin_n 2._o when_o the_o vomit_v begin_v to_o cease_v you_o must_v distinguish_v well_o whether_o it_o be_v because_o the_o person_n be_v better_a and_o the_o stomach_n discharge_v of_o the_o rosin_n or_o because_o tire_a nature_n yield_v itself_o to_o rest_n by_o a_o sort_n of_o succumbency_n to_o the_o fatigue_n or_o leipothymy_n you_o may_v easy_o distinguish_v these_o case_n for_o in_o the_o first_o case_n every_o thing_n seem_v better_a and_o in_o the_o last_o worse_o save_v that_o the_o vomit_v cease_v which_o be_v a_o endeavour_n of_o more_o vigorous_a nature_n and_o therefore_o its_o fail_n be_v now_o a_o ill_a sign_n in_o this_o case_n good_a old_a wine_n and_o spirituoâ—_n cordial_n which_o may_v rouse_v and_o invigorate_v nature_n and_o also_o engage_v with_o the_o rosin_n by_o their_o sulphureous_a spirit_n must_v be_v of_o excellent_a use._n note_v that_o if_o you_o want_v salt_n of_o tartar_n other_o lixivial_a salt_n may_v serve_v as_o those_o of_o wormwood_n broom_n etc._n etc._n only_o you_o must_v give_v at_o least_o one_o three_o more_o and_o in_o case_n of_o great_a haste_n and_o urgency_n you_o may_v give_v the_o very_a ash_n of_o wormwood_n broom_n or_o any_o vegetable_a in_o 2_o or_o 3_o time_n the_o quantity_n as_o the_o salt_n be_v to_o be_v give_v in_o 2_o or_o 3_o spoonful_n of_o brandy_n or_o a_o glass_n of_o old_a wine_n or_o both_o mix_v together_o for_o the_o very_a roughness_n of_o the_o ash_n will_v in_o some_o measure_n contribute_v to_o wear_v off_o the_o rosin_n and_o thereby_o assist_v the_o lixivial_a salt_n that_o be_v in_o they_o 3._o if_o the_o quantity_n of_o the_o resinous_n opium_n be_v great_a it_o will_v be_v convenient_a when_o you_o perceive_v the_o vomit_v begin_v to_o abate_v to_o give_v as_o much_o of_o daffee_n elixir_n or_o tinctura_fw-la sacra_fw-la make_v in_o some_o spirituous_a liquor_n as_o do_v usual_o give_v six_o stool_n it_o be_v best_o purge_v with_o a_o liquid_a because_o speedy_a in_o operation_n and_o that_o it_o shall_v be_v spirituous_a to_o help_v the_o dissolution_n of_o the_o rosin_n 1._o note_v that_o you_o also_o take_v care_v not_o to_o be_v too_o busy_a with_o spirituous_a liquor_n when_o they_o be_v much_o relax_v and_o have_v such_o symptom_n as_o drunken_a people_n have_v especial_o if_o they_o appear_v in_o a_o high_a degree_n for_o too_o much_o of_o they_o may_v promote_v the_o relaxation_n 2._o note_v that_o in_o faint_n or_o leipothymy_n after_o such_o vomit_n and_o struggle_v of_o nature_n you_o must_v not_o so_o much_o excite_v they_o by_o grievous_a sensation_n as_o pinch_v prick_a etc._n etc._n for_o those_o leipothymy_n be_v as_o be_v say_v a_o sort_n of_o recruit_v as_o sleep_n be_v and_o therefore_o the_o last_o refuge_n of_o nature_n for_o that_o end_n but_o with_o spirituous_a and_o comfortable_a thing_n as_o know_v that_o there_o be_v a_o awake_n by_o recruit_v which_o be_v natural_a as_o well_o as_o by_o grievous_a sensation_n which_o be_v force_v and_o unnatural_a as_o have_v be_v show_v ii_o to_o cure_v the_o effect_n of_o too_o much_o relaxation_n by_o a_o excessive_a do_v etc._n etc._n first_o you_o must_v be_v satisfy_v that_o the_o ill_a effect_n thereof_o be_v from_o too_o much_o relaxation_n 1._o by_o consider_v the_o preparation_n of_o opium_n that_o be_v take_v for_o if_o you_o find_v that_o it_o be_v such_o as_o have_v the_o rosin_n due_o separate_v from_o it_o you_o may_v be_v sure_a that_o the_o ill_a effect_n be_v only_o from_o relaxation_n because_o the_o do_v be_v too_o great_a or_o if_o it_o be_v a_o preparation_n that_o have_v the_o rosin_n so_o subdue_v or_o alter_v as_o you_o find_v direct_v to_o render_v it_o safe_a you_o may_v presume_v the_o ill_a effect_n be_v from_o over_o relaxation_n for_o such_o preparation_n be_v otherwise_o safe_a and_o innocent_a except_o when_o the_o largeness_n of_o the_o do_v as_o that_o of_o good_a wine_n cause_v too_o much_o relaxation_n 2._o by_o the_o symptom_n which_o be_v these_o viz._n alienation_n of_o the_o mind_n loss_n of_o memory_n stupidity_n sleepiness_n sopor_n failures_n of_o the_o sense_n as_o
darkness_n of_o the_o eye_n see_v thing_n double_a various_a colour_n before_o the_o eye_n loss_n of_o feel_v ease_n from_o pain_n etc._n etc._n deadness_n of_o the_o eye_n to_o the_o view_n dilatation_n of_o the_o pupilla_fw-la efflorescence_n of_o the_o skin_n laxity_n of_o the_o low_a jaw_n intumescence_n and_o laxity_n of_o the_o lip_n falter_v of_o the_o tongue_n sardonick_a laughter_n laxity_n and_o weakness_n of_o all_o part_n a_o general_a ineptitude_n to_o motion_n failure_n in_o make_v water_n go_v to_o stool_n and_o in_o all_o thing_n that_o require_v strength_n contraction_n motion_n etc._n etc._n difficulty_n of_o breathe_v a_o wide_a and_o slow_a pulse_n a_o condition_n in_o general_a very_a like_o that_o of_o drunkenness_n which_o also_o proceed_v from_o relaxation_n second_o when_o you_o be_v satisfy_v that_o relaxation_n be_v the_o cause_n use_v all_o mean_n to_o procure_v a_o due_a contraction_n of_o all_o part_n which_o be_v to_o be_v do_v 1._o by_o remove_v the_o cause_n of_o the_o relaxation_n 2._o by_o use_v all_o good_a mean_n for_o contraction_n first_o therefore_o give_v a_o brisk_a quick_a and_o strong_a vomit_n both_o to_o discharge_v the_o opiate_n and_o cause_n contraction_n of_o part_n by_o a_o grievous_a sensation_n proportion_n it_o to_o the_o deadness_n stupidity_n or_o sleepiness_n of_o the_o person_n so_o as_o to_o give_v it_o of_o twice_o the_o ordinary_a strength_n of_o vomit_n in_o case_n there_o be_v great_a danger_n from_o those_o symptom_n and_o that_o they_o be_v of_o a_o high_a nature_n after_o the_o person_n have_v vomit_v 3_o or_o 4_o time_n or_o so_o often_o as_o that_o you_o may_v judge_v the_o stomach_n well_o clear_v of_o the_o opiate_n give_v half_o a_o ounce_n of_o cream_n of_o tartar_n fine_o powder_v in_o thin_a broth_n whey_n water_n small_a beer_n or_o any_o convenient_a liquid_a which_o will_v correct_v the_o opiate_n if_o any_o remain_v at_o stomach_n turn_v the_o vomit_n to_o a_o purger_n to_o clear_v the_o intestine_n also_o and_o contribute_v much_o to_o the_o contraction_n of_o part_n which_o you_o must_v always_o have_v in_o your_o thought_n as_o the_o roll_a intention_n in_o this_o case_n therefore_o second_o you_o must_v use_v contracter_n all_o the_o time_n the_o chief_a of_o which_o be_v cold_a grievous_a sensation_n or_o pain_n terror_n fear_v voluntary_a motion_n and_o acid_n which_o last_n can_v be_v so_o well_o use_v during_o the_o vomit_v lest_o they_o stop_v it_o therefore_o especial_o if_o the_o person_n be_v very_o stupid_a keep_v he_o very_o cold_a for_o he_o will_v hardly_o feel_v it_o nor_o take_v cold_a because_o the_o relaxation_n and_o the_o insensibleness_n of_o grievance_n by_o cold_a etc._n etc._n keep_v the_o pore_n open_a let_v he_o be_v if_o possible_a in_o some_o motion_n as_o walk_v hew_v saw_v knock_v tug_v etc._n etc._n the_o more_o violent_a it_o be_v the_o better_a because_o it_o cause_v more_o contraction_n and_o agitation_n to_o prevent_v sopor_n to_o force_v he_o to_o motion_n if_o need_v be_v prick_a pinch_a or_o whip_v he_o about_o the_o leg_n etc._n etc._n will_v be_v of_o good_a use_n because_o grievous_a sensation_n add_v defensive_a contraction_n which_o be_v the_o great_a sort_n to_o that_o of_o the_o intentive_a contraction_n by_o voluntary_a motion_n these_o mean_n fail_v he_o shall_v be_v expose_v stark_o naked_a to_o the_o cold_a air_n and_o in_o desperate_a case_n throw_v sudden_o at_o unaware_o into_o cold_a water_n by_o which_o mean_v you_o cause_n terror_n surprise_v and_o cold_a which_o be_v the_o high_a and_o most_o forcible_a contracter_n to_o conspire_v to_o the_o contraction_n of_o part_n hence_o it_o be_v that_o drunken_a people_n who_o be_v so_o from_o relaxation_n become_v sober_a as_o in_o a_o moment_n by_o that_o mean_n all_o the_o time_n but_o during_o the_o vomit_v let_v he_o use_v cold_a acid_n in_o great_a plenty_n and_o very_o manifest_o acid_a for_o they_o will_v not_o only_o contribute_v to_o contraction_n but_o very_o much_o correct_v the_o opiate_n to_o this_o end_n juice_n of_o orange_n or_o lemon_n verjuice_n or_o water_n acidulate_v to_o a_o good_a degree_n by_o verjuice_n vinegar_n juice_n of_o lemon_n spirit_n of_o vitriol_n sulphur_n or_o the_o like_a will_v be_v very_o proper_a where_o you_o have_v not_o the_o convenience_n to_o plunge_v they_o into_o cold_a water_n as_o be_v direct_v dash_v or_o pump_v very_o cold_a water_n or_o water_n with_o a_o four_o part_n of_o vinegar_n upon_o their_o naked_a body_n will_v be_v of_o great_a use_n especial_o if_o surprise_o do_v to_o cause_v the_o more_o terror_n and_o concern_v these_o thing_n may_v be_v do_v more_o or_o lâ—ss_o as_o cause_n may_v require_v which_o must_v be_v leave_v to_o the_o discretion_n of_o the_o present_a physician_n or_o friend_n and_o standard_n by_o in_o case_n there_o be_v no_o physician_n i_o only_o caution_n that_o contracter_n shall_v not_o be_v use_v too_o spare_o and_o that_o you_o shall_v never_o cease_v to_o advance_v in_o the_o use_n of_o they_o till_o you_o perceive_v their_o good_a effect_n and_o then_o to_o continue_v they_o as_o occasion_n require_v note_v that_o the_o case_n may_v well_o happen_v that_o the_o rosin_n may_v stick_v at_o stomach_n and_o yet_o no_o sign_n or_o symptom_n appear_v but_o those_o of_o relaxation_n by_o reason_n that_o the_o feel_n at_o stomach_n may_v thereby_o be_v disable_v to_o take_v any_o notice_n of_o it_o to_o be_v sure_a of_o this_o you_o have_v no_o other_o mean_n because_o the_o symptom_n and_o effect_n of_o grievous_a sensation_n can_v appear_v where_o it_o be_v not_o for_o the_o aforesaid_a reason_n but_o to_o examine_v whether_o the_o opiate_n be_v a_o resinous_a one_o as_o crude_a opium_n extract_v out_o of_o spirit_n of_o wine_n or_o the_o like_a for_o than_o you_o may_v conclude_v especial_o if_o they_o be_v give_v in_o a_o massy_a solid_a form_n as_o that_o of_o pill_n etc._n etc._n without_o sever_n the_o particle_n of_o the_o rosin_n by_o other_o thing_n as_o the_o yolk_n of_o a_o egg_n etc._n etc._n that_o the_o rosin_n may_v in_o all_o probability_n stick_v at_o stomach_n though_o its_o symptom_n do_v not_o appear_v for_o the_o aforesaid_a reason_n in_o such_o a_o case_n the_o best_a advice_n that_o i_o can_v give_v be_v external_o to_o use_v all_o contract_n mean_v as_o be_v direct_v and_o internal_o the_o mean_v prescribe_v for_o dissolution_n of_o the_o rosin_n for_o you_o will_v thereby_o answer_v both_o intention_n failure_n of_o make_v water_n often_o happen_v in_o these_o case_n which_o you_o may_v general_o help_v by_o only_o clap_v the_o scrotum_fw-la to_o the_o cold_a chamber_n pot_n or_o into_o cold_a water_n and_o if_o that_o will_v not_o do_v put_v some_o vinegar_n into_o the_o water_n and_o that_o fail_v he_o must_v be_v strip_v and_o cold_a water_n pump_v or_o dash_v upon_o the_o region_n of_o the_o bladder_n iii_o to_o cure_v the_o ill_a effect_n of_o a_o long_a and_o lavish_a use_n of_o opium_n these_o effect_n as_o you_o may_v easy_o observe_v if_o you_o take_v a_o view_n of_o they_o where_o they_o be_v enumerate_v in_o chap._n 6._o be_v either_o 1._o from_o a_o overmuch_o and_o habitual_a relaxation_n of_o part_n as_o weakness_n a_o moapish_a disposition_n diminution_n of_o appetite_n weakness_n of_o digestion_n dropsy_n weakness_n of_o memory_n etc._n etc._n or_o 2._o from_o acrimony_n as_o frequent_a irritation_n to_o make_v water_n priapism_n erection_n of_o the_o penis_n fruitless_a inclination_n to_o venery_n etc._n etc._n in_o this_o case_n as_o in_o that_o of_o old_a drunkard_n which_o be_v much_o the_o same_o there_o be_v no_o good_a to_o be_v do_v till_o the_o habitual_a cause_n be_v remove_v viz._n the_o take_v of_o opium_n which_o sudden_o to_o leave_v off_o be_v as_o be_v show_v very_o dangerous_a therefore_o in_o order_n to_o leave_v it_o off_o safe_o 1._o you_o must_v stop_v your_o hand_n and_o not_o increase_v the_o do_v that_o be_v take_v by_o which_o mean_v it_o will_v come_v gradual_o to_o have_v little_a or_o no_o effect_n 2._o when_o you_o find_v that_o it_o be_v come_v to_o that_o pass_n your_o work_n be_v half_o do_v then_o only_o lessen_v it_o 100th_o part_n every_o day_n till_o you_o come_v to_o take_v none_o at_o all_o 3._o if_o during_o this_o retrograde_a course_n you_o find_v any_o faintness_n drink_v a_o glass_n of_o good_a stomach-wine_n toties_fw-la quoties_fw-la as_o gentian_n or_o centary_a wine_n or_o the_o like_a make_v by_o infusion_n in_o claret_n or_o if_o you_o want_v such_o a_o glass_n of_o the_o claret_n itself_o which_o thing_n will_v excite_v the_o spirit_n and_o help_v digestion_n 4._o when_o you_o have_v quite_o end_v the_o take_v of_o opium_n continue_v to_o use_v such_o wine_n when_o you_o be_v faint_a and_o every_o morning_n take_v in_o a_o glass_n of_o
gentian_a wine_n two_o dram_fw-la of_o the_o chalybeate_a wine_n describe_v in_o the_o london_n dispensatory_a increase_v about_o a_o scruple_n every_o day_n till_o you_o come_v to_o half_a a_o ounce_n which_o take_v for_o two_o month_n at_o least_o afterward_o decrease_v as_o you_o increase_v till_o you_o come_v to_o one_o drachm_n and_o so_o give_v over_o but_o if_o you_o find_v oâ—osion_n you_o may_v continue_v that_o course_n long_o or_o as_o long_o as_o your_o physician_n think_v fit_a after_o all_o you_o may_v use_v a_o glass_n of_o claret_n when_o faint_a but_o be_v sure_a to_o be_v moderate_a and_o not_o run_v from_o one_o excess_n to_o another_o as_o for_o the_o acrimony_n of_o blood_n that_o be_v more_o during_o the_o take_v of_o opium_n and_o will_v soon_o after_o gradual_o wear_v off_o especial_o by_o the_o course_n direct_v if_o not_o camphire_n be_v the_o adequate_a remedy_n of_o which_o with_o equal_a part_n of_o white_a rosin_n and_o q._n s._n of_o mucilage_n of_o gum._n tragac._n you_o may_v make_v pill_n of_o â—_o grain_n weight_n take_v 4_o of_o they_o every_o night_n at_o bedtime_n in_o a_o rear_n yolk_n of_o a_o egg_n as_o long_o as_o it_o be_v necessary_a for_o camphire_n by_o its_o fine_a sulphur_n correct_v the_o volatile_a acrimony_n of_o cantharides_n opium_n etc._n etc._n and_o so_o allay_v titillation_n to_o venery_n etc._n etc._n as_o be_v observe_v iv_o the_o ill_a effect_n of_o a_o sudden_a leave_v off_o of_o opium_n as_o anxiety_n distress_n depression_n of_o spirit_n which_o as_o be_v say_v be_v very_o dangerous_a be_v remedy_v no_o other_o way_n but_o either_o 1._o by_o return_v to_o the_o use_v of_o opium_n which_o be_v a_o most_o certain_a cure_n and_o afterward_o if_o you_o please_v give_v over_o the_o use_n of_o it_o after_o the_o manner_n that_o i_o direct_v which_o you_o will_v find_v to_o be_v safe_a nor_o can_v i_o advise_v you_o to_o trust_v any_o other_o method_n of_o leave_v it_o off_o unless_o it_o be_v 2._o by_o substitute_v wine_n instead_o of_o opium_n which_o be_v not_o quite_o so_o safe_a or_o certain_a your_o best_a method_n of_o use_v it_o be_v to_o drink_v a_o good_a glass_n of_o it_o so_o often_o as_o to_o keep_v the_o comfort_n thereof_o at_o stomach_n continual_o that_o so_o it_o may_v answer_v the_o more_o permanent_a effect_n of_o opium_n and_o keep_v you_o from_o a_o faint_a condition_n but_o see_v also_o that_o this_o course_n be_v not_o convenient_a to_o be_v continue_v long_o you_o must_v gradual_o lessen_v the_o do_v of_o this_o as_o you_o be_v direct_v to_o do_v that_o of_o opium_n till_o you_o come_v to_o take_v none_o or_o at_o least_o a_o moderate_a and_o wholesome_a quantity_n note_v that_o if_o such_o as_o use_v to_o take_v opium_n be_v even_o almost_o expire_a for_o want_n of_o it_o you_o must_v to_o prevent_v imminent_a death_n give_v a_o liquid_a preparation_n thereof_o to_o the_o value_n of_o what_o the_o person_n be_v use_v to_o take_v in_o a_o cordial_a vehicle_n as_o spirit_n of_o wine_n brandy_n or_o the_o like_a because_o such_o hot_a spirituous_a vehicles_n do_v as_o have_v be_v show_v immediate_o give_v some_o comfort_n by_o actuate_a and_o warm_v our_o spirit_n till_o the_o opium_n come_v to_o operate_v which_o will_v not_o be_v long_o because_o it_o be_v in_o a_o liquid_a form_n if_o you_o find_v the_o person_n sink_v notwithstanding_o he_o may_v be_v keep_v up_o by_o repeat_v the_o brandy_n or_o cordial_n without_o any_o opium_n in_o it_o till_o the_o opiate_n operate_v which_o will_v certain_o by_o god_n help_n set_v he_o right_n in_o case_n it_o do_v but_o begin_v to_o operate_v before_o he_o be_v dead_a see_v the_o philos._n transact_v for_o june_n july_n august_n 1696._o note_v that_o it_o be_v a_o very_a false_a imagination_n that_o author_n have_v of_o the_o turk_n capacity_n by_o nature_n climate_n or_o the_o like_a to_o take_v more_o opium_n or_o in_o great_a quantity_n than_o we_o may_v but_o that_o they_o make_v more_o use_n of_o it_o and_o by_o that_o mean_n come_v to_o take_v 2_o or_o 3_o dram_fw-la a_o day_n for_o they_o begin_v with_o such_o small_a quantity_n as_o we_o common_o give_v till_o by_o a_o long_a custom_n of_o take_v it_o they_o come_v to_o take_v the_o say_a quantity_n which_o be_v but_o small_a in_o comparison_n of_o what_o several_a english_a people_n that_o have_v be_v use_v to_o it_o do_v or_o have_v take_v as_o i_o can_v name_v several_a to_o you_o if_o i_o have_v not_o reason_n to_o the_o contrary_a however_o i_o be_o at_o liberty_n to_o tell_v you_o the_o quantity_n though_o i_o must_v forbear_v name_v the_o person_n some_o have_v daily_o take_v 2_o 3_o 4_o 5_o 6_o dram_fw-la nay_o i_o have_v hear_v of_o some_o that_o have_v take_v a_o ounce_n a_o day_n and_o of_o one_o that_o take_v two_o ounce_n whereas_o the_o learned_a and_o curious_a dr._n edward_n smith_n can_v find_v none_o about_o smyrna_n who_o take_v above_o 3_o dram_fw-la a_o day_n all_o this_o be_v most_o agreeable_a to_o reason_n and_o the_o whole_a current_n of_o my_o discourse_n viz._n that_o it_o can_v be_v better_o bear_v in_o cold_a than_o hot_a wether_n and_o consequent_o in_o cold_a than_o hot_a climate_n by_o firm_a flesh_v person_n than_o such_o as_o have_v soft_a and_o flaccid_a flesh_n as_o the_o southern_a people_n have_v in_o comparison_n of_o the_o northern_a and_o such_o as_o inhabit_v cold_a country_n therefore_o you_o may_v be_v sure_a that_o such_o as_o inquire_v into_o the_o cause_n why_o the_o turk_n and_o other_o eastern_a people_n can_v take_v great_a quantity_n than_o we_o can_v seek_v for_o the_o reason_n of_o thing_n before_o they_o know_v the_o fact_n nay_o when_o the_o fact_n be_v quite_o contrary_a to_o what_o they_o build_v upon_o we_o may_v as_o well_o expect_v edify_v discourse_n from_o they_o that_o inquire_v why_o fire_n be_v cold_a water_n dry_a and_o the_o like_a as_o from_o such_o as_o suppose_v thing_n contrary_a to_o true_a and_o sensible_a experience_n chap._n xxix_o some_o general_a rule_n caution_n &c_n &c_n concern_v the_o use_n of_o opium_n though_o there_o be_v hardly_o any_o rule_n caution_n or_o thing_n worthy_a of_o observation_n concern_v the_o use_n of_o opium_n but_o what_o be_v imply_v or_o easy_o inferable_a from_o what_o have_v be_v say_v nor_o now_o that_o the_o true_a nature_n of_o opium_n be_v discover_v can_v there_o be_v such_o fear_n and_o jealoufy_v which_o multiply_v caution_n concern_v the_o administration_n thereof_o for_o every_o one_o may_v now_o easy_o see_v wherein_o its_o danger_n and_o benefit_n lie_v yet_o because_o a_o chapter_n of_o rule_n and_o caution_n may_v be_v expect_v as_o be_v usual_a and_o to_o have_v a_o single_a view_n of_o such_o as_o lie_v more_o scatter_v and_o not_o so_o ready_o find_v in_o the_o body_n of_o the_o book_n i_o will_v to_o introduce_v the_o use_n of_o opium_n with_o more_o clearness_n and_o perfect_a security_n give_v you_o a_o collection_n of_o general_a rule_n and_o caution_n concern_v its_o use_n whereof_o some_o be_v mention_v and_o most_o inferable_a from_o the_o premise_n i._o as_o to_o its_o substance_n 1._o it_o shall_v be_v always_o give_v free_v from_o its_o resinous_n part_n if_o you_o can_v get_v such_o a_o preparation_n 2._o it_o be_v also_o neat_a and_o convenient_a that_o it_o shall_v be_v free_v from_o all_o its_o earth_n and_o dress_n 3._o never_o give_v opium_n but_o either_o so_o prepare_v or_o with_o its_o rosin_n so_o subdue_v segregated_a or_o alter_v as_o i_o have_v show_v in_o the_o safe_a preparation_n thereof_o iâ—_n follow_v that_o 4._o crude_a opium_n and_o extract_v make_v in_o sulphureous_a spirit_n be_v utter_o to_o be_v reject_v 5._o never_o give_v it_o mix_v or_o join_v with_o resinous_a thing_n as_o have_v be_v intimate_v 6._o never_o mix_v or_o join_v it_o with_o other_o opiate_n 1._o because_o none_o of_o they_o be_v so_o good_a 2._o because_o they_o be_v not_o so_o well_o know_v 3._o because_o it_o make_v the_o do_v more_o uncertain_a 4._o because_o those_o other_o opiate_n be_v use_v unprepared_a 7._o pil._n e_o styrace_n because_o make_v of_o resinous_a opium_n join_v with_o resinous_a thing_n as_o styrax_fw-la calam_fw-la and_o olibanum_n be_v a_o insufferable_a preparation_n though_o commend_v and_o therefore_o have_v frequent_a ill_a effect_n to_o my_o knowledge_n 8._o pil._n â—_o cynoglossâ_fw-la be_v such_o another_o have_v two_o opiate_n in_o it_o beside_o opium_n extract_v out_o of_o spirit_n of_o wine_n which_o be_v far_o worse_a than_o crude_a opium_n though_o by_o the_o way_n of_o eminence_n call_v opium_n prepare_v in_o our_o dispensatory_a styrax_n calam_fw-la and_o olibanum_n which_o be_v resinous_a 9_o laudan_n lond._n be_v also_o a_o ill_a preparation_n as_o have_v the_o
part_n themselves_o do_v also_o due_o contract_n which_o opium_n hinder_v 6._o you_o have_v much_o the_o same_o reason_n not_o to_o give_v they_o soon_o after_o other_o large_a evacuation_n where_o a_o due_a contraction_n of_o the_o part_n be_v requisite_a as_o after_o tapping_n or_o paracentesis_n in_o dropsy_n childbirth_n etc._n etc._n 7._o opiate_n be_v best_a give_v in_o the_o morning_n to_o cause_n euphory_n or_o brisk_a effect_n because_o the_o refreshment_n gain_v by_o the_o night_n sleep_n do_v not_o only_o concur_v towards_o euphory_n and_o briskness_n but_o also_o much_o oppose_v sleepiness_n and_o drowsiness_n which_o be_v not_o consistent_a with_o brisk_a effect_n vi_o as_o to_o person_n 1._o it_o be_v not_o convenient_a to_o give_v opiate_n to_o person_n very_o young_a or_o very_a old_a 2._o they_o agree_v better_o with_o man_n than_o woman_n or_o child_n with_o man_n of_o a_o robu_v and_o hard_a rather_o than_o of_o a_o weak_a fine_a tender_a and_o soft_a texture_n with_o such_o as_o have_v a_o strong_a digestion_n than_o a_o weak_a and_o in_o general_a with_o the_o strong_a rather_o than_o the_o weak_a therefore_o 3._o never_o give_v they_o to_o person_n that_o be_v very_o weak_a especial_o if_o they_o take_v or_o digest_v no_o sustenance_n or_o extreme_o little_a for_o reason_n already_o give_v nor_o to_o such_o as_o be_v near_o their_o end_n or_o almost_o expire_a ☞_o except_o it_o be_v for_o want_v of_o opium_n or_o by_o extremity_n of_o contraction_n by_o terror_n pain_n cold_a convulsion_n etc._n etc._n for_o than_o it_o will_v do_v wonder_n in_o preserve_a people_n that_o be_v otherwise_o past_a all_o hope_n by_o relax_v take_v away_o pain_n contraction_n etc._n etc._n 4._o it_o be_v not_o so_o agreeable_a to_o the_o very_a fat_a or_o moist_a because_o they_o may_v be_v over-relaxed_n nor_o to_o the_o very_a lean_a and_o dry_a etc._n etc._n especial_o to_o cause_n sleep_n because_o it_o be_v apt_a to_o irritate_fw-la and_o actuate_v their_o spirit_n too_o much_o by_o which_o mean_v sleep_n be_v much_o hinder_v vii_o as_o to_o malady_n and_o disease_n etc._n etc._n i._o opiate_n be_v not_o convenient_a in_o relaxation_n as_o such_o as_o general_a palsy_n hemiphlegia_n palsy_n of_o the_o eye_n deadness_n of_o they_o dilatation_n of_o the_o pupil_n relaxation_n of_o the_o tympan_n of_o the_o ear_n of_o one_o side_n of_o the_o face_n which_o make_v the_o other_o side_n contract_n and_o and_o so_o draw_v the_o face_n awry_o for_o it_o be_v not_o a_o spasm_n or_o convulsion_n as_o man_n imagine_v of_o the_o contract_a side_n but_o a_o resolution_n of_o the_o other_o which_o permit_v the_o antagonist_n muscle_n of_o that_o side_n to_o contract_n without_o opposition_n and_o draw_v the_o face_n towards_o the_o strong_a or_o sound_a side_n relaxation_n of_o the_o uuula_fw-la or_o the_o annex_v value_n which_o last_o be_v know_v by_o snuffle_v without_o any_o other_o evident_a cause_n or_o by_o observe_v that_o it_o do_v not_o shut_v in_o sound_a u_o in_o but_o cut_z etc._n etc._n by_o itself_o relaxation_n of_o the_o larynx_n and_o windpipe_n which_o be_v know_v by_o a_o hoarse_a kind_n of_o whisper_n without_o a_o cold_a or_o any_o evident_a cause_n of_o the_o pharynx_n or_o gullet_n which_o be_v know_v by_o a_o depravation_n of_o swallow_v without_o pain_n or_o tumour_n or_o any_o evident_a cause_n a_o paralytical_a asthma_n or_o difficulty_n of_o breathe_v wherein_o man_n heave_v the_o shoulder_n without_o any_o apparent_a cause_n relaxation_n of_o the_o stomach_n as_o when_o meat_n stay_v too_o long_o at_o stomach_n etc._n etc._n a._n palsy_n of_o the_o intestine_n or_o gut_n as_o when_o one_o be_v bind_v and_o can_v refer_v it_o to_o any_o other_o cause_n of_o the_o bladder_n when_o one_o can_v make_v water_n without_o any_o other_o cause_n to_o refer_v it_o to_o relaxation_n of_o the_o sphincter_n of_o the_o bladder_n and_o anâ—_n that_o be_v when_o urine_n or_o ordure_n fall_v from_o one_o involuntary_o nor_o be_v they_o convenient_a in_o bath_n unless_o great_a relaxation_n as_o for_o passage_n of_o the_o stone_n etc._n etc._n be_v intend_v nor_o in_o rupture_n as_o bronchocele_v of_o the_o windpipe_n exomphalos_n of_o the_o navel_n bubonocele_n of_o the_o groin_n or_o the_o fall_n of_o humour_n gut_n fat_a etc._n etc._n into_o the_o scrotum_fw-la or_o of_o the_o fundament_n womb_n or_o the_o vagina_n etc._n etc._n except_o it_o be_v to_o reduce_v they_o nor_o in_o lunation_n sprain_n laxity_n and_o weakness_n of_o joint_n limb_n back_o etc._n etc._n extension_n of_o nerve_n tendon_n ligament_n etc._n etc._n nor_o where_o relaxation_n do_v or_o may_v improve_v the_o distemper_n or_o do_v harm_n as_o in_o apoplectical_a and_o soporose_a case_n as_o coma_n caros_n lethargy_n etc._n etc._n weakness_n of_o memory_n stupidity_n morosiâ—_n nightmare_n drunkenness_n etc._n etc._n syncopes_fw-la and_o faint_n from_o relaxation_n as_o the_o original_a cause_n as_o from_o excess_n of_o joy_n pleasure_n large_a evacuation_n when_o the_o part_n can_v well_o and_o due_o contract_v upon_o what_o remain_v as_o after_o childbirth_n profuse_a hemorrhage_n tapping_n or_o paracentesis_n or_o any_o large_a evacuation_n of_o humour_n in_o dropsy_n of_o the_o belly_n breast_n or_o head_n nor_o as_o have_v be_v hint_v in_o dropsy_n though_o without_o any_o such_o evacuation_n unless_o it_o be_v upon_o some_o special_a consideration_n of_o the_o learned_a nor_o in_o tremble_n or_o shake_v of_o the_o head_n or_o hand_n etc._n etc._n from_o weakness_n as_o in_o old_a age_n nor_o in_o flux_n from_o relaxation_n as_o too_o much_o sweat_n gonorrhaea_n simplex_n diabetes_n nocturnal_a pollution_n chylous_a flux_n lientery_n involuntary_a flux_n of_o urine_n or_o ordure_n and_o some_o sort_n of_o immoderate_a flux_n of_o the_o menses_fw-la or_o lochia_n which_o owe_v their_o cause_n to_o relaxation_n or_o aptitude_n to_o abortion_n from_o that_o cause_n and_o indeed_o general_o in_o woman_n with_o child_n lest_o it_o shall_v cause_v abortion_n by_o relax_v the_o neck_n of_o the_o womb._n or_o where_o contraction_n be_v beneficial_a as_o to_o empty_v a_o foul_a or_o replete_a stomach_n choler_n etc._n etc._n by_o vomit_v or_o stool_n or_o a_o ill_a humour_n any_o way_n therefore_o ii_o opiate_n be_v not_o convenient_a when_o grievous_a sensation_n be_v useful_a as_o to_o excite_v expectoration_n when_o matter_n threaten_v suffocation_n in_o vomicas_fw-la pleurisy_n peripneumonias_n consumption_n spit_v of_o blood_n etc._n etc._n when_o hunger_n call_v for_o food_n and_o restaurative_n that_o of_o stuff_v at_o stomach_n excite_v vomit_v that_o of_o urine_n solicit_v we_o to_o a_o due_a excretion_n thereof_o that_o of_o ill_a matter_n at_o gut_n cause_v a_o evacuation_n thereof_o so_o that_o when_o a_o crisis_n be_v to_o be_v by_o the_o help_n of_o grievous_a sensation_n or_o irritation_n opiate_n be_v not_o convenient_a for_o it_o take_v off_o the_o sense_n of_o irritation_n but_o when_o a_o crisis_n be_v to_o be_v by_o relaxation_n as_o by_o open_v the_o pore_n to_o cause_n sweat_n perspiration_n etc._n etc._n then_o be_v it_o of_o excellent_a use_n so_o that_o great_a question_n that_o have_v very_o much_o puzzle_v the_o learned_a whether_o opium_n be_v convenient_a before_o a_o crisis_n &_o c_o be_v plain_o and_o mechanical_o answer_v iii_o opiate_n be_v not_o convenient_a where_o titillation_n by_o the_o acrimony_n of_o volatile_a salt_n be_v the_o cause_n of_o the_o disease_n as_o in_o troublesome_a erection_n priapism_n nocturnal_a pollution_n venereal_a fury_n too_o much_o salacity_n and_o titillation_n itch_n of_o the_o uterus_fw-la scrotum_fw-la penis_n skin_n in_o general_n etc._n etc._n iv_o i_o scarce_o need_v tell_v any_o that_o opiate_n be_v inconvenient_a when_o the_o meconium_n of_o child_n shall_v be_v evacuate_v or_o when_o one_o be_v bind_v in_o body_n or_o apt_a to_o be_v so_o but_o there_o may_v be_v a_o time_n when_o the_o learned_a physician_n may_v think_v fit_a to_o give_v they_o even_o to_o the_o costive_a in_o urgent_a case_n for_o he_o can_v order_v somewhat_o along_o with_o they_o or_o soon_o after_o to_o open_v the_o body_n who_o may_v also_o see_v cause_n sometime_o to_o vary_v from_o these_o general_a rule_n when_o necessity_n and_o good_a reason_n direct_v he_o so_o to_o do_v though_o they_o be_v nevertheless_o general_a in_o their_o nature_n and_o not_o to_o be_v transgress_v without_o special_a cause_n and_o mature_a deliberation_n v._o opiate_n be_v not_o so_o convenient_a where_o there_o be_v much_o slimy_a moist_a and_o phlegmatic_a humour_n by_o reason_n that_o the_o part_n be_v subject_a in_o such_o case_n to_o be_v too_o much_o relax_v i_o have_v be_v the_o full_a especial_o upon_o the_o head_n of_o disease_n that_o i_o may_v hereafter_o have_v nothing_o to_o do_v but_o to_o show_v the_o beneficial_a use_n of_o opiate_n due_o prepare_v more_o particular_o of_o the_o panacea_n
that_o when_o people_n be_v in_o a_o untoward_a condition_n or_o as_o they_o call_v it_o out_o of_o sod_n the_o next_o day_n after_o drink_v man_n often_o advise_v take_v the_o hair_n of_o the_o same_o dog_n that_o be_v drink_v some_o of_o the_o same_o wine_n or_o liquor_n it_o be_v best_o for_o they_o to_o use_v it_o as_o i_o just_a now_o direct_v for_o their_o case_n upon_o the_o good_a effect_n of_o the_o wine_n cease_v be_v much_o like_a that_o upon_o the_o go_n off_o of_o the_o operation_n of_o opium_n which_o may_v also_o in_o this_o case_n be_v use_v instead_o of_o wine_n to_o procure_v a_o better_a and_o blither_n condition_n for_o that_o day_n that_o use_v to_o be_v very_o troublesome_a to_o drinker_n 3._o note_v that_o good_a preparation_n of_o opium_n may_v be_v convenient_o use_v to_o horse_n to_o prevent_v their_o be_v tire_v or_o take_v off_o their_o weariness_n and_o cause_v they_o to_o go_v on_o but_o i_o will_v not_o advise_v any_o preparation_n in_o this_o case_n but_o the_o liquid_a panacea_fw-la in_o good_a ale_n or_o beer_n and_o that_o only_a in_o the_o same_o quantity_n as_o be_v use_v to_o man_n till_o far_a experience_n embolden_v the_o practice_n by_o such_o mean_n i_o can_v doubt_v it_o any_o jade_n may_v be_v make_v to_o appear_v lively_a go_v well_o etc._n etc._n chap._n xxxii_o of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o compose_v the_o sensitive_a soul_n spirit_n etc._n etc._n i_o have_v show_v how_o and_o why_o it_o compose_v and_o quiet_v the_o sensitive_a soul_n spirit_n blood_n stomach_n etc._n etc._n and_o by_o that_o mean_n allay_v all_o the_o fury_n commotion_n perturbation_n and_o turbulent_a exorbitance_n thereof_o and_o that_o often_o without_o sleep_n but_o much_o better_a with_o it_o it_o follow_v therefore_o 1._o that_o it_o prevent_v and_o take_v off_o all_o fret_n and_o turbulent_a passion_n of_o the_o sensitive_a soul_n as_o anger_n uneasy_a agitation_n and_o toss_v of_o the_o mind_n peevishness_n fretfulness_n discontent_n disquietude_n dissatisfaction_n murmur_n turmoiling_n and_o vexatious_a thought_n anxiety_n solicitude_n etc._n etc._n and_o all_o the_o evil_a effect_n thereof_o as_o watch_n waste_v of_o spirit_n or_o strength_n lossitude_n hypochondriacal_a melancholy_n cachexy_n scurvy_n etc._n etc._n but_o these_o last_o belong_v most_o proper_o to_o its_o alterative_a faculty_n or_o virtue_n 2._o all_o involuntary_a furious_a agitation_n of_o the_o sensitive_a soul_n and_o spirit_n as_o madness_n more_o especial_o melancholy_a madness_n or_o such_o as_o proceed_v from_o grievous_a thought_n or_o apprehension_n loss_n cross_n despair_n fear_n terror_n or_o the_o like_a but_o they_o be_v not_o so_o good_a in_o merry_a madness_n as_o those_o from_o joy_n venereal_a fury_n and_o suchlike_a which_o answer_v the_o great_a dispute_n about_o opiate_n in_o madness_n delirium_n epileptical_a fit_n convulsion_n general_a and_o particular_a as_o those_o of_o the_o head_n rise_v of_o the_o light_n vomit_n hiccough_n sabbing_n kecking_n convulsive_a asthma_n palpitation_n and_o tremble_n of_o the_o heart_n shake_v and_o shivering_n upon_o fear_n terror_n cold_a pain_n ague-fits_a convulsive_a colick_n hysterick_n fit_v iliack_a passion_n etc._n etc._n 3._o all_o fever_n and_o fret_n of_o humour_n that_o happen_v from_o any_o of_o the_o aforesaid_a cause_n or_o from_o any_o violent_a motion_n voluntary_a or_o involuntary_a as_o labour_n run_v hew_v fight_a or_o any_o vehement_a exercise_n ratling_n toss_n concussion_n in_o coach_n wagon_n boat_n in_o stormy_a wether_n violent_a ride_v etc._n etc._n or_o from_o heat_n of_o fire_n sun_n bath_n hothouse_n bagnio_n crowd_n lie_v too_o many_o in_o one_o bed_n or_o with_o too_o much_o clothes_n or_o from_o grievous_a sensation_n irritation_n or_o pain_n as_o fever_n upon_o inflammation_n abscess_n bubo_n stone_n colic_n cardialgia_n wound_n fracture_n dislocation_n confusion_n amputation_n lithotomy_n paracentesis_n or_o any_o painful_a operation_n of_o the_o noble_a art_n of_o chirurgery_n agony_n or_o pain_n of_o the_o smallpox_n as_o its_o second_o fever_n and_o the_o like_a or_o from_o flux_n as_o tedious_a and_o turbulent_a vomit_n diarrheas_n dysentery_n cholera_n iliack_a passion_n artificial_a purge_v and_o all_o symptomatick_a or_o immaterial_a fever_n whatsoever_o which_o either_o never_o have_v any_o matter_n but_o proceed_v from_o such_o agitate_a cause_n as_o i_o mention_v or_o remain_v as_o some_o do_v after_o the_o grieve_v matter_n be_v carry_v off_o by_o vomit_v purge_v etc._n etc._n i_o forbear_v mention_v pleurisy_n and_o peripneumonia_n among_o the_o fever_n that_o it_o prevent_v or_o take_v off_o because_o there_o be_v great_a dispute_n whether_o opiate_n be_v convenient_a in_o those_o case_n which_o i_o hope_v to_o determine_v unless_o it_o be_v when_o the_o say_v distemper_n be_v come_v to_o that_o pass_n that_o it_o be_v dangerous_a to_o cause_v sleep_n or_o take_v away_o any_o of_o the_o sense_n of_o the_o irritation_n of_o the_o matter_n to_o be_v expectorate_v lest_o it_o shall_v be_v too_o much_o amass_v in_o the_o bronchias_n or_o windpipe_n and_o so_o choke_v the_o person_n i_o see_v no_o cause_n to_o forbid_v they_o any_o more_o than_o sleep_v or_o opiate_n in_o other_o inflammation_n wherein_o they_o be_v high_o beneficial_a to_o give_v ease_n cause_n sleep_n compose_v the_o spirit_n and_o take_v off_o or_o at_o least_o moderate_a the_o fever_n but_o i_o see_v many_o good_a reason_n to_o use_v they_o 1._o because_o as_o a_o sal-volatile-oleosum_a they_o reserate_v and_o resolve_v clammy_a humour_n and_o be_v so_o agreeable_a in_o principle_n as_o menstraums_n shall_v be_v to_o the_o thing_n to_o be_v resolve_v i_o can_v doubt_v but_o red_a poppy_n be_v upon_o experience_n state_v a_o specific_a in_o those_o case_n for_o that_o reason_n 2._o because_o these_o distemper_n as_o hypocrates_n speak_v be_v from_o a_o segregation_n of_o humour_n by_o agitation_n etc._n etc._n and_o opiate_n excellent_a composer_n thereof_o 3._o because_o they_o be_v such_o great_a discusser_n and_o 4._o open_v the_o pore_n to_o let_v the_o discuss_v matter_n quite_o out_o of_o the_o body_n 5._o because_o it_o may_v be_v that_o by_o its_o relaxation_n upon_o such_o resolution_n the_o lodge_v matter_n may_v be_v cause_v to_o flow_v off_o and_o circulate_v again_o and_o so_o be_v gradue_v discuss_v and_o carry_v off_o by_o the_o open_a pore_n 6._o because_o it_o envigorate_v nature_n to_o perform_v those_o thing_n and_o 7._o give_v ease_n and_o recruit_v of_o the_o spirit_n by_o sleep_n so_o that_o all_o thing_n consider_v i_o think_v as_o experience_n assure_v we_o that_o red_a poppy_n or_o opiate_n in_o due_a quantity_n be_v the_o very_o best_a remedy_n that_o can_v be_v use_v hence_o it_o be_v that_o wedelius_n call_v opium_n a_o antipleuritick_n specific_a he_o have_v observe_v as_o i_o and_o other_o have_v do_v that_o the_o whole_a course_n of_o the_o disease_n and_o expectoration_n will_v succeed_v much_o better_a by_o their_o use._n he_o add_v also_o that_o he_o have_v very_o often_o cure_v they_o by_o its_o help_n without_o let_v of_o blood_n which_o be_v a_o infallible_a sign_n of_o their_o good_a effect_n since_o the_o pleurisy_n can_v hardly_o be_v cure_v without_o bleed_v i_o can_v see_v how_o a_o effect_n that_o bear_v such_o analogy_n to_o sleep_n can_v do_v any_o more_o harm_n than_o sleep_n etmuller_n also_o advise_v the_o give_v of_o opiate_n not_o only_o in_o the_o beginning_n but_o also_o during_o the_o increase_n of_o the_o pleurisy_n or_o peripneumoniae_fw-la so_o that_o i_o conclude_v that_o they_o be_v of_o excellent_a use_n in_o those_o disease_n unless_o it_o be_v when_o sleep_n or_o they_o may_v cause_v too_o much_o insensibleness_n of_o the_o bronchias_n and_o so_o retard_v expectoration_n when_o the_o case_n be_v such_o that_o the_o want_v thereof_o may_v endanger_v the_o person_n be_v be_v choke_v we_o have_v also_o many_o history_n of_o person_n cure_v in_o other_o fever_n by_o large_a dose_n of_o opiate_n i_o suppose_v that_o resinous_a opiate_n cause_v vomit_v and_o great_a disturbance_n by_o reason_n of_o ill_a digestion_n in_o those_o case_n may_v be_v one_o great_a cause_n of_o people_n fear_n and_o jeolousy_n in_o give_v opiate_n which_o be_v easy_o prevent_v by_o give_v liquid_a opiate_n void_a of_o any_o resinous_a particle_n as_o the_o liquid_a panacea_fw-la etc._n etc._n 4._o it_o do_v by_o compose_v quiet_v and_o appease_v the_o motion_n and_o perturbation_n of_o the_o blood_n conduce_v much_o to_o the_o stop_n of_o its_o efflux_n in_o hemorrhage_n or_o bleeding_n that_o be_v unnatural_a as_o at_o nose_n in_o spit_v and_o vomit_v of_o blood_n bleed_v at_o the_o hemorrhoid_v in_o dysentery_n piss_v of_o blood_n etc._n etc._n and_o sometime_o in_o profuse_a menses_fw-la when_o they_o happen_v from_o a_o fever_n or_o too_o much_o motion_n of_o the_o blood_n and_o
vagina_n in_o which_o case_n it_o be_v of_o neat_a use_n both_o by_o relax_v and_o take_v away_o pain_n during_o the_o operation_n it_o may_v be_v also_o of_o use_n when_o the_o strictness_n of_o the_o collum_n uteri_fw-la hinder_v the_o admission_n of_o sem._n viril_n both_o as_o a_o general_a relaxer_n and_o as_o cause_v great_a pleasure_n of_o those_o part_n and_o a_o proportionable_a relaxation_n thereof_o for_o it_o be_v by_o the_o pleasure_n in_o coition_n that_o the_o collum_n uteri_fw-la be_v open_v or_o relax_v as_o be_v observe_v which_o immediate_o close_v again_o when_o the_o sense_n of_o pleasure_n be_v end_v yea_o and_o so_o much_o the_o strict_a because_o the_o loss_n of_o pleasure_n be_v as_o be_v show_v a_o kind_a of_o grievance_n hence_o it_o be_v that_o omne_fw-la animal_n post_fw-la coitum_fw-la est_fw-la triste_fw-fr and_o not_o because_o of_o loss_n of_o spirit_n as_o be_v vulgar_o imagine_v for_o we_o can_v lose_v little_a or_o no_o spirit_n by_o that_o which_o be_v so_o separate_v for_o excretion_n before_o hand_n as_o the_o semen_n be_v 5._o to_o enlarge_v any_o part_n for_o the_o due_a reception_n of_o what_o be_v convenient_a or_o necessary_a as_o the_o breast_n to_o receive_v milk_n by_o which_o mean_v it_o come_v to_o be_v such_o great_a increaser_n of_o milk_n the_o seminal_a vessel_n as_o sem._n virile_a do_v upon_o puberty_n to_o receive_v the_o semen_n thus_o it_o cause_v the_o penis_n to_o grow_v as_o the_o semen_n upon_o puberty_n cause_v it_o and_o cock_n comb_n turkeycock_n red_a bag_n at_o the_o neck_n proboscis_n etc._n etc._n to_o grow_v as_o the_o time_n they_o be_v fit_a for_o or_o begin_v to_o tread_v for_o the_o relaxation_n cause_v by_o the_o pleasure_n of_o the_o semen_n make_v the_o party_n more_o capable_a of_o the_o nutriment_n thus_o it_o be_v that_o sleep_v cause_n the_o growth_n fatten_v and_o thrive_a of_o animal_n and_o red_a nose_n to_o grow_v so_o large_a by_o frequent_a relaxation_n upon_o the_o pleasure_n of_o wine_n ale_z etc._n etc._n as_o be_v say_v to_o which_o quantity_n distend_v the_o part_n may_v in_o the_o last_o mention_v case_n contribute_v i._o the_o form_n of_o opiate_n in_o this_o case_n may_v be_v either_o solid_a or_o liquid_a as_o you_o think_v â—it_a ii_o the_o dose_n must_v be_v proportion_v to_o the_o relaxation_n that_o you_o desire_v for_o more_o relax_n more_o and_o less_o less_o so_o must_v it_o be_v also_o proportion_v to_o the_o contraction_n that_o it_o be_v to_o take_v away_o therefore_o very_o grievous_a passion_n or_o sensation_n which_o cause_n proportionable_a contraction_n require_v great_a dose_n because_o their_o grievance_n and_o contraction_n do_v strong_o oppose_v the_o pleasure_n and_o relaxation_n that_o opiate_n cause_n therefore_o great_a pain_n as_o you_o will_v find_v in_o its_o due_a place_n require_v a_o extraordinary_a do_v iii_o the_o vehicle_n in_o contraction_n from_o grievous_a passion_n shall_v be_v wine_n or_o some_o comfortable_a cordial_n except_o they_o be_v the_o more_o turbulent_a passion_n as_o anger_n fury_n etc._n etc._n where_o composer_n as_o emulsion_n milk_n and_o water_n etc._n etc._n be_v best_a in_o all_o other_o case_n emollient_a and_o supply_a vehicles_n be_v most_o proper_a as_o soft_a smooth_a and_o slippery_a 〈◊〉_d broth_n etc._n etc._n iv_o the_o time_n to_o give_v they_o be_v at_o the_o due_a distance_n before_o bed_n time_n when_o the_o intention_n be_v consistent_a with_o sleep_n which_o itself_o be_v a_o great_a relaxer_n otherwise_o any_o time_n will_v serve_v as_o occasion_n or_o the_o intention_n of_o the_o physician_n require_v it_o v._o the_o regimen_n 1._o as_o to_o meat_n and_o drink_n be_v use_v moist_a emollient_a and_o lubricate_a thing_n as_o smooth_a broth_n somewhat_o â—at_a butter_v root_n herb_n sauce_n 〈◊〉_d milk-meat_n young_a flesh_n as_o of_o roast_a pig_n 〈◊〉_d lamb_n etc._n etc._n smooth_a drink_n as_o alc_n 〈◊〉_d etc._n etc._n 2._o as_o to_o sleep_v and_o wake_v that_o relax_n and_o this_o contract_n therefore_o that_o conduce_v this_o hinder_v 3._o as_o to_o rest_n and_o motion_n that_o relax_n and_o this_o contract_n 4._o as_o to_o the_o passion_n of_o the_o mind_n the_o pleasant_a as_o 〈◊〉_d joy_n pleasure_n comfort_n and_o all_o such_o do_v relax_v and_o the_o grievous_a as_o terror_n fear_v grief_n melancholy_n etc._n etc._n contract_n as_o pain_n do_v 5._o as_o to_o air_n the_o warm_a and_o moist_a or_o that_o when_o the_o quicksilver_n be_v low_a in_o the_o barometer_n or_o weatherglass_n do_v relax_v as_o do_v warm_a bath_n fomentation_n etc._n etc._n especial_o if_o emollient_a dry_v and_o cold_a air_n and_o that_o when_o the_o quicksilver_n be_v high_a do_v cause_n contraction_n 6._o as_o to_o excretion_n and_o retention_n general_o excretion_n do_v make_v room_n and_o way_n for_o thing_n to_o pass_v through_o or_o into_o the_o relaxed_a part_n as_o clyster_v for_o passage_n of_o the_o stone_n child_n reduction_n of_o hernias_fw-la etc._n etc._n but_o be_v sure_a not_o to_o make_v the_o excretion_n grievous_a because_o all_o grievous_a sensation_n cause_v contraction_n chap._n xxxiv_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o take_v away_o pain_n or_o grievous_a sensation_n this_o it_o do_v as_o be_v show_v by_o divert_v the_o sensitive_a soul_n and_o introduce_v a_o sense_n of_o pleasure_n which_o be_v contrary_a to_o grievous_a sensation_n or_o pain_n can_v be_v in_o the_o same_o subject_a with_o pain_n but_o chief_o and_o mechanical_o by_o relax_v all_o part_n and_o permit_v the_o springy_a animal_n spirit_n to_o expand_v and_o so_o become_v unfit_a to_o carry_v impression_n smart_o which_o be_v requisite_a to_o cause_v a_o sense_n of_o pain_n as_o have_v be_v prove_v therefore_o it_o be_v of_o most_o happy_a and_o glorious_a use_n in_o all_o pain_n but_o especial_o to_o be_v use_v 1._o in_o such_o as_o be_v not_o for_o any_o benefit_n to_o the_o person_n pain_v in_o order_n to_o alter_v or_o evacuate_v the_o grieve_v cause_n as_o in_o pocky_a scorbutical_a or_o hypochondriacal_a pain_n or_o such_o as_o proceed_v from_o any_o ill_a habit_n of_o body_n etc._n etc._n 2._o where_o pain_n hinder_v the_o take_v away_o of_o its_o cause_n or_o some_o benefit_n as_o when_o the_o pain_n of_o the_o stone_n do_v by_o contract_v the_o part_n hinder_v its_o own_o passage_n that_o of_o a_o tenesmus_n hinder_v go_v to_o stool_n that_o of_o the_o sphincter_n of_o the_o bladder_n hinder_v its_o open_n to_o let_v out_o urine_n clod_v blood_n phlegm_n matter_n or_o any_o such_o thing_n when_o that_o of_o the_o neck_n of_o the_o wâ—mb_n hinder_v delivery_n of_o a_o child_n afterbirth_n mole_n clod_v blood_n etc._n etc._n that_o of_o the_o mouth_n of_o the_o stomach_n hinder_v vomit_v when_o requisite_a or_o that_o of_o the_o pylorus_n hinder_v the_o detrusion_n of_o chyle_n or_o that_o of_o the_o intestine_n as_o by_o a_o inflammation_n etc._n etc._n stop_v the_o passage_n of_o the_o ordure_n and_o cause_v a_o iliack_a passion_n or_o that_o of_o the_o guilet_n hinder_v swollow_v of_o the_o larynx_n breathe_v or_o that_o of_o any_o part_n hinder_v perspiration_n or_o desire_a sweat_n or_o that_o of_o the_o venereal_a part_n stop_v the_o menses_fw-la or_o lochia_n etc._n etc._n in_o all_o which_o case_n it_o be_v and_o must_v in_o all_o reason_n be_v of_o excellent_a and_o if_o due_o manage_v of_o almost_o if_o not_o altogether_o infallible_a effect_n by_o take_v away_o the_o pain_n which_o cause_v the_o part_n to_o contract_v and_o make_v the_o stop_n etc._n etc._n 3._o where_o the_o cause_n of_o the_o pain_n can_v be_v remove_v but_o by_o perspiration_n sweat_v menses_fw-la lochia_n or_o urine_n â—s_n in_o pain_n in_o the_o habit_n of_o the_o body_n limb_n etc._n etc._n from_o cold_a wind_n or_o vapour_n gout_n rheumatism_n stitch_n pleurisy_n inflammation_n and_o many_o of_o the_o case_n aforemention_v it_o be_v excellent_a as_o it_o be_v 4._o where_o the_o pain_n irritation_n or_o grievous_a sensation_n cause_v nature_n to_o work_v irregular_o as_o in_o iliack_n â—_z hysterick_a fit_n fruitless_a convulsion_n canine_a apâ—_n etc._n etc._n in_o which_o case_n it_o excel_v all_o other_o mean_n for_o many_o reason_n 5._o where_o the_o pain_n be_v not_o likely_a to_o have_v a_o timely_a effect_n for_o good_a till_o people_n may_v be_v too_o much_o wear_v out_o 6._o in_o all_o pain_n that_o have_v not_o any_o material_a cause_n from_o the_o â—_z &c._n &c._n of_o the_o body_n as_o such_o as_o happen_v from_o passion_n wound_n prick_v of_o nerve_n tendon_n fracture_n dislocation_n amputation_n severe_a chirurgical_a operation_n etc._n etc._n 7._o in_o all_o pain_n from_o inflammation_n suppuration_n abseess_n tumour_n where_o repulsion_n be_v not_o convenient_a or_o possible_a 8._o in_o all_o pain_n that_o be_v more_o likely_a to_o cause_v fever_n than_o any_o
the_o pore_n therefore_o 1._o it_o be_v of_o excellent_a use_n to_o carry_v away_o noxious_a vapour_n or_o effluvia_n by_o the_o pore_n of_o the_o skin_n to_o prevent_v putrefaction_n and_o cure_v they_o to_o carry_v off_o venomous_a particle_n in_o the_o plague_n infectious_a distemper_n bite_n of_o serpent_n mad_a dog_n etc._n etc._n ill_a fume_n wind_n in_o the_o blood_n or_o habit_n of_o the_o body_n that_o cause_v stitch_n tumour_n etc._n etc._n 2._o to_o carry_v off_o noxious_a humour_n the_o same_o way_n especial_o such_o as_o stagnate_n or_o offend_v in_o the_o habit_n of_o the_o body_n as_o in_o cold_n intercutaneous_a water_n leâ—cophlegmatia_n and_o sometime_o in_o dropsy_n as_o dr._n willis_n observe_v in_o declination_n of_o disease_n to_o carry_v off_o the_o concoct_v morbid_v matter_n in_o rheumatism_n and_o gout_n particular_o that_o which_o be_v call_v the_o wind_n gout_n 3._o when_o perspiration_n be_v any_o way_n hinder_v as_o by_o grievous_a passion_n sensation_n or_o pain_n acid_a austere_a or_o cold_a humour_n by_o which_o many_o disease_n be_v cause_v thus_o it_o be_v very_o useful_a in_o grief_n sorrow_n anxiety_n solicitude_n melancholy_a panic_n fear_n gachexy_n scurvy_n hypochondriacal_a case_n wherein_o it_o perform_v wonderful_o when_o all_o thing_n fail_v as_o you_o find_v in_o chap._n 24._o 4._o to_o promote_v the_o menses_fw-la or_o lochia_n when_o stop_v by_o reason_n of_o the_o constriction_n of_o the_o pore_n by_o such_o grievous_a passion_n or_o sensation_n or_o by_o acid_n austere_a or_o cold_a humour_n external_a cold_a etc._n etc._n by_o its_o relax_a and_o open_v the_o pore_n and_o way_n and_o solicit_v the_o part_n by_o a_o gentle_a agreeable_a titillation_n hence_o some_o just_o call_v it_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o be_v a_o opener_n of_o the_o mouth_n of_o the_o vein_n or_o bloud-vessel_n by_o which_o mean_v as_o have_v be_v show_v puberty_n coition_n etc._n etc._n do_v kind_o and_o natural_o cause_v the_o menses_fw-la to_o flow_v while_o the_o same_o relaxation_n cause_v a_o increase_n of_o blood_n as_o it_o do_v of_o milk_n by_o widen_v the_o vessel_n this_o be_v all_o mechanical_a truth_n that_o will_v answer_v upon_o experience_n as_o the_o most_o ingenious_a dr._n edw._n brown_n can_v witness_v who_o be_v the_o only_a man_n as_o far_o as_o i_o know_v that_o seem_v to_o have_v this_o practice_n 5._o it_o promote_v urine_n by_o the_o like_a open_n or_o relax_v of_o the_o pore_n of_o the_o kidney_n by_o its_o titillate_v volatile_a salt_n as_o cantharides_n bee_n pismire_n millepedes_n etc._n etc._n do_v 6._o it_o may_v probable_o be_v of_o great_a use_n in_o cutaneous_a distemper_n either_o by_o take_v large_a quantity_n of_o proper_a liquid_n and_o sweat_v they_o out_o again_o by_o its_o help_n to_o wash_v of_o ill_a particle_n or_o to_o open_v the_o pore_n for_o the_o admission_n of_o external_a medicament_n note_v that_o they_o be_v natural_a flux_n it_o promote_v and_o unnatural_a one_o that_o it_o stop_v which_o prove_v its_o operate_n as_o a_o entire_a friend_n to_o nature_n both_o way_n i._o the_o form_n may_v be_v which_o you_o please_v or_o be_v most_o agreeable_a to_o the_o patient_n ii_o the_o do_v moderate_a except_o it_o be_v when_o extraordinary_a relaxation_n or_o open_n of_o the_o pore_n be_v desire_v iii_o the_o vehicle_n shall_v be_v such_o as_o be_v proper_a to_o prepare_v the_o humour_n to_o pass_v by_o sweat_n or_o insensible_a perspiration_n or_o the_o blood_n by_o the_o menses_fw-la and_o lochia_n therefore_o shall_v general_o speak_v consist_v of_o attenuate_a thing_n as_o volatile_a spirit_n and_o in_o the_o plague_n venomous_a and_o contagious_a case_n of_o alexipharmack_n of_o diuretic_n to_o promote_v urine_n and_o so_o in_o all_o case_n of_o what_o be_v proper_a in_o the_o respective_a humour_n for_o their_o exit_fw-la or_o passage_n iv_o the_o time_n because_o sleep_n conduce_v to_o open_v the_o pore_n may_v be_v at_o the_o due_a distance_n before_o bedtime_n but_o that_o hinder_v not_o but_o it_o may_v be_v give_v when_o there_o be_v occasion_n at_o any_o other_o time_n in_o the_o plague_n it_o shall_v be_v so_o often_o give_v as_o to_o keep_v the_o pore_n always_o open_a mayern_n glve_v a_o instance_n of_o a_o physician_n that_o have_v all_o sign_n of_o death_n petechiae_fw-la a_o carbuncle_n etc._n etc._n who_o recover_v by_o take_v laudanum_n 6_o time_n a_o day_n i_o suppose_v 24_o hour_n or_o the_o natural_a day_n be_v mean_v thereby_o v._o the_o regimen_n must_v be_v such_o as_o be_v proper_a convenient_a and_o usual_a in_o the_o respective_a case_n for_o it_o be_v endless_a to_o mention_v all_o it_o require_v a_o volume_n to_o cause_n sweat_n much_o temperate_a liquid_n must_v be_v always_o give_v especial_o in_o fever_n or_o dry_a body_n as_o the_o hypochondriacal_a etc._n etc._n most_o part_n of_o the_o liquid_n shall_v be_v give_v before_o the_o opiate_n that_o they_o may_v have_v time_n to_o get_v into_o the_o blood_n by_o that_o time_n the_o opiate_n operate_v which_o do_v so_o as_o be_v show_v while_o it_o be_v at_o stomach_n to_o move_v the_o menses_fw-la proper_a mean_n shall_v be_v use_v for_o a_o due_a time_n before_o the_o use_v thereof_o because_o the_o effect_v expect_v in_o this_o case_n from_o opiate_n be_v only_o to_o open_v the_o way_n or_o pore_n so_o humour_n in_o leucophlegmatia_n &c._n &c._n shall_v be_v due_o prepare_v for_o the_o like_a reason_n to_o cause_n perspiration_n it_o be_v convenient_a in_o cold_a constitution_n and_o old_a people_n gentle_o to_o warm_v the_o blood_n with_o 2_o or_o 3_o glass_n of_o generous_a wine_n a_o little_a garlic_n onion_n selery_n or_o the_o like_a to_o attenuate_v and_o cause_v evaporation_n which_o heat_v promote_v but_o if_o you_o overheat_v the_o blood_n it_o hinder_v perspiration_n by_o its_o grow_a grievous_a for_o what_o be_v so_o cause_v contraction_n and_o close_n of_o the_o pore_n note_v that_o nothing_o can_v be_v so_o good_a to_o cause_v perspiration_n or_o sweat_n because_o it_o not_o only_o open_v the_o pore_n but_o take_v away_o any_o grievous_a passion_n or_o sensation_n that_o may_v close_v they_o and_o atenuate_v resolve_n etc._n etc._n by_o its_o volatile_a salt_n chap._n xxxviii_o of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n as_o a_o titillative_a this_o it_o do_v as_o be_v show_v by_o its_o volatile_a salt_n as_o cantharides_n bee_n pismire_n sem._n viril_n etc._n etc._n therefore_o 1._o it_o be_v of_o great_a use_n to_o excite_v to_o venery_n cause_n erection_n to_o actuate_v a_o dull_a semen_n for_o the_o sake_n of_o lawful_a propagation_n 2._o to_o increase_v the_o semen_n 1._o by_o the_o titillation_n of_o the_o venereal_a part_n which_o invite_v it_o thither_o by_o the_o agitation_n thereof_o as_o frication_n of_o the_o breast_n and_o those_o part_n cause_n increase_n of_o milk_n and_o the_o semen_n 2._o by_o the_o pleasure_n thereof_o relax_v the_o part_n which_o cause_v a_o great_a flux_n of_o it_o as_o of_o milk_n to_o the_o breast_n and_o nourishment_n to_o any_o part._n it_o be_v observable_a how_o desirous_a rachel_n be_v barren_a be_v of_o the_o opiate_n call_v mandrake_n so_o that_o she_o part_v with_o her_o belove_a husband_n to_o her_o sister_n leah_n for_o a_o night_n to_o purchase_v it_o whether_o it_o be_v any_o mean_n to_o cause_v she_o to_o conceive_v which_o she_o do_v afterward_o be_v not_o to_o be_v determine_v though_o it_o seem_v not_o altogether_o unlikely_a 3._o it_o be_v use_n to_o increase_v milk_n be_v speak_v of_o in_o the_o chapter_n of_o its_o use_n to_o relax_v only_o it_o do_v it_o here_o as_o titillate_v and_o there_o as_o relax_v 4._o it_o conduce_v to_o move_v the_o menses_fw-la by_o its_o titillation_n 5._o the_o titillation_n of_o its_o volatile_a salt_n as_o cantharides_n etc._n etc._n do_v move_v we_o to_o urine_n i._o the_o form_n be_v whole_o indifferent_a ii_o the_o dose_n must_v be_v large_a and_o general_o great_a than_o any_o i_o have_v mention_v and_o possible_o require_v a_o repetition_n thereof_o to_o excite_v to_o venery_n though_o i_o shall_v not_o prescribe_v any_o more_o than_o i_o have_v in_o the_o table_n of_o dose_n but_o leave_v it_o to_o judicious_a physician_n to_o do_v as_o they_o think_v â—it_a where_o there_o be_v a_o just_a cause_n for_o its_o use_n which_o i_o will_v not_o expose_v to_o every_o lustful_a goat_n it_o be_v not_o unlikely_a but_o one_o great_a cause_n of_o the_o ignorance_n of_o its_o use_n to_o excite_v venery_n in_o these_o western_a part_n of_o the_o world_n may_v be_v the_o smallness_n of_o the_o dose_n that_o we_o use_v beside_o the_o reason_n mention_v in_o chap._n 8._o and_o that_o such_o circumstance_n may_v occasion_v the_o dispute_n and_o contradiction_n that_o have_v be_v about_o the_o effect_n of_o opium_n whereas_o there_o be_v
chapter_n of_o its_o use_n to_o cause_v sleep_n v._o the_o regimen_n must_v be_v exact_a temperance_n and_o moderation_n in_o all_o thing_n and_o 1._o as_o to_o diet_n let_v it_o be_v appropriate_v to_o the_o disease_n and_o always_o of_o such_o thing_n as_o the_o stomach_n digest_v without_o any_o difficulty_n or_o disturbance_n 2_o as_o to_o sleep_v it_o shall_v be_v moderate_a yet_o so_o much_o as_o full_o recruit_n and_o refresh_v 3._o as_o to_o rest_n and_o motion_n the_o like_a moderation_n must_v be_v use_v for_o motion_n must_v not_o be_v violent_a or_o over-wasting_a of_o the_o spirit_n in_o any_o respect_n yet_o must_v gentle_a motion_n and_o exercise_n be_v use_v ride_v on_o horseback_n to_o such_o as_o can_v do_v it_o be_v a_o very_a wholesome_a exercise_n 4._o as_o to_o excretion_n and_o retension_n you_o shall_v never_o purge_v or_o vomit_n during_o its_o use_n unless_o there_o be_v a_o very_a special_a cause_n and_o then_o i_o will_v have_v the_o vomit_n to_o be_v only_o carduate_v water_n and_o for_o stool_n only_o so_o much_o of_o the_o scot_n pill_n or_o stomach_n pill_n as_o will_v serve_v to_o open_v the_o body_n to_o be_v take_v at_o bedtime_n or_o at_o such_o time_n of_o the_o night_n as_o to_o cause_v no_o disturbance_n before_o you_o be_v up_o in_o the_o morning_n but_o general_o speak_v cause_v not_o evacuation_n be_v best_a but_o what_o be_v the_o consequence_n of_o the_o panacea_fw-la itself_o which_o cause_v the_o best_a most_o natural_a universal_a and_o considerable_a evacuation_n by_o the_o pore_n 5._o as_o to_o the_o air_n the_o dry_a and_o temperate_a as_o to_o heat_n and_o cold_a but_o rather_o incline_v to_o coldness_n be_v the_o best_a for_o you_o can_v so_o well_o err_v on_o this_o hand_n because_o the_o pore_n will_v be_v keep_v open_a and_o cold_n prevent_v in_o a_o high_a manner_n by_o the_o use_n of_o the_o panacea_fw-la beside_o that_o coolness_n be_v most_o agreeable_a to_o digestion_n 6._o as_o to_o passion_n of_o the_o mind_n all_o the_o grievous_a one_o shall_v be_v avoid_v and_o a_o fine_a even_a cheerfulness_n maintain_v as_o mâ—ch_v as_o may_v be_v it_o will_v be_v very_o easy_o continue_v by_o the_o help_n of_o the_o panacea_fw-la which_o cause_v it_o above_o all_o thing_n 1._o note_v that_o these_o direction_n do_v general_o concern_v its_o use_n in_o chronical_a case_n for_o as_o to_o acute_a disease_n and_o particular_a gas_n it_o must_v be_v leave_v to_o the_o management_n of_o the_o present_a physician_n 2._o note_v that_o its_o use_n as_o a_o evacuative_a have_v be_v sufficient_o treat_v of_o in_o the_o chapter_n of_o its_o use_n to_o cause_v flux_n and_o evacuation_n 3._o note_n that_o notwithstanding_o all_o i_o have_v say_v of_o the_o most_o excellent_a qualification_n of_o the_o panacea_fw-la of_o opium_n i_o submit_v all_o to_o far_a experience_n at_o the_o introduction_n of_o which_o i_o main_o aim_v by_o endeavour_v to_o take_v off_o people_n fear_n and_o jealousy_n which_o have_v ever_o be_v the_o great_a hinderer_n of_o improvement_n in_o cure_n more_o especial_o in_o reference_n to_o the_o use_v of_o opiate_n which_o without_o doubt_n will_v cure_v many_o disease_n more_o than_o ever_o they_o be_v use_v for_o at_o least_o as_o alteratives_n which_o if_o my_o discourse_n do_v occasion_n i_o shall_v thank_v and_o praise_v the_o author_n of_o all_o good_a for_o make_v i_o instrumental_a thereto_o chap._n xli_o of_o the_o external_n use_v of_o opium_n it_o be_v external_n use_v be_v as_o the_o internal_a either_o i._o as_o a_o pleaser_n of_o sensation_n or_o a_o opiate_n spe_fw-mi cial_o so_o call_v or_o ii_o as_o a_o alterative_a first_o as_o a_o pleaser_n of_o sensation_n or_o a_o opiate_n proper_o and_o special_o so_o call_v it_o be_v scarce_o worth_a while_n to_o treat_v of_o it_o because_o of_o the_o uncertainty_n ineffectualness_n and_o sometime_o danger_n thereof_o unless_o it_o be_v to_o caution_n man_n concern_v it_o for_o my_o part_n i_o seldom_o or_o never_o use_v it_o external_o unless_o it_o be_v in_o venice-treacle_n diascordium_n or_o mithridate_n which_o have_v but_o little_a quantity_n thereof_o nor_o can_v i_o see_v why_o it_o shall_v be_v at_o all_o use_v external_o as_o a_o opiate_n except_o it_o be_v when_o opiate_n can_v be_v use_v internal_o where_o they_o have_v more_o even_o certain_a and_o better_a effect_n or_o in_o very_o â—ew_a case_n which_o will_v be_v mention_v the_o main_a therefore_o that_o i_o can_v do_v in_o this_o case_n be_v to_o acquaint_v you_o what_o other_o have_v sound_a by_o experience_n concern_v its_o external_a use._n 1._o it_o have_v be_v find_v dangerous_a to_o apply_v opiate_n to_o the_o suture_n of_o the_o head_n it_o have_v kill_v some_o and_o galen_n be_v against_o it_o l._n 2._o de_fw-fr comp._n med._n i_o have_v somewhere_o read_v of_o a_o man_n who_o after_o a_o certain_a contest_v for_o victory_n be_v very_o hot_a take_v off_o his_o helmet_n to_o refresh_v himself_o after_o the_o victory_n he_o have_v obtain_v which_o helmet_n his_o emulator_n smear_v on_o the_o inside_n with_o opium_n he_o afterward_o put_v it_o on_o and_o soon_o die_v 2._o it_o be_v apply_v more_o safe_o to_o the_o forehead_n or_o temple_n but_o the_o quantity_n of_o half_a a_o scruple_n shall_v not_o be_v exceed_v in_o this_o case_n fernelius_n commend_v the_o application_n of_o it_o to_o the_o forehead_n in_o headache_n frenzy_n &c_n &c_n mix_v with_o ointment_n wedelius_n do_v also_o use_n venice_n treacle_n and_o extract_v of_o opium_n to_o the_o temple_n with_o good_a success_n in_o pain_n of_o the_o head_n he_o also_o find_v the_o like_a success_n in_o apply_v it_o behind_o the_o ear_n note_v that_o the_o continuance_n and_o constancy_n of_o its_o operation_n where_o it_o take_v effect_v apply_v external_o may_v be_v very_o beneficial_a in_o some_o case_n but_o even_o that_o may_v be_v answer_v by_o internal_a use_n if_o it_o be_v repeat_v 3._o all_o or_o most_o do_v agree_v that_o it_o be_v too_o acrimonious_a to_o be_v apply_v to_o the_o eye_n 4._o geigâ—rus_n fernelius_n heurnius_n etc._n etc._n do_v commend_v its_o use_n to_o smell_v to_o be_v make_v into_o a_o ball_n etc._n etc._n with_o odoriferous_a thing_n and_o i_o have_v a_o opinion_n that_o this_o way_n of_o use_v it_o may_v be_v excellent_a condition_v that_o not_o above_o half_a a_o scruple_n of_o opium_n be_v use_v 1._o because_o but_o a_o small_a quantity_n and_o that_o of_o its_o fine_a part_n be_v thus_o receive_v into_o the_o body_n 2._o because_o it_o may_v be_v remove_v at_o pleasure_n and_o then_o as_o some_o say_v the_o effect_v immediate_o cease_v this_o be_v very_o well_o worth_a the_o experiment_n for_o it_o will_v be_v very_o neat_a to_o be_v able_a to_o cause_v sleep_n and_o its_o other_o effect_n with_o safety_n as_o long_o or_o as_o short_a a_o time_n as_o we_o please_v and_o no_o long_o for_o this_o can_v be_v do_v when_o it_o be_v internal_o give_v but_o its_o operation_n will_v have_v its_o course_n without_o extraordinary_a mean_n and_o trouble_n but_o when_o external_o use_v the_o very_a cause_n of_o the_o danger_n if_o any_o shall_v hâ—ppen_v can_v be_v immediate_o remove_v by_o take_v of_o the_o opiate_n from_o the_o nose_n 5._o that_o of_o geigerus_fw-la and_o langius_n use_v only_o one_o 〈◊〉_d of_o opium_n to_o the_o puncture_n or_o little_a wound_n make_v by_o a_o leecâ—_n behind_o the_o ear_n to_o cause_v sleep_n and_o that_o with_o effect_n seem_v to_o i_o to_o he_o attribute_v more_o to_o the_o bleed_a which_o always_o incline_v man_n to_o sleep_v than_o to_o the_o opium_n 6._o crude_a opium_n have_v kill_v people_n by_o put_v it_o in_o hollow_a tooth_n as_o some_o observer_n aver_v 7._o apply_v to_o the_o ear_n it_o relax_n and_o as_o it_o be_v resolve_v the_o tympan_n and_o other_o delicate_a membrane_n concern_v and_o thereby_o offend_v the_o hear_v 9_o galen_n seem_v to_o be_v against_o the_o application_n of_o it_o to_o the_o nape_n of_o the_o neck_n because_o so_o near_o the_o original_a of_o the_o nerve_n note_v that_o it_o be_v not_o convenient_a to_o use_v it_o where_o resolution_n and_o relaxation_n may_v do_v any_o harm_n as_o be_v say_v of_o the_o tympan_n of_o the_o ear_n etc._n etc._n 10._o venice_n treacle_n mithridate_n and_o diascordium_n be_v safe_o apply_v external_o to_o the_o region_n of_o the_o stomach_n to_o appease_v vomit_v and_o hiccough_n moderate_a looseness_n etc._n etc._n 11._o savanarola_n and_o octavius_n horatianus_n use_v it_o to_o the_o navel_n to_o cause_v sleep_n and_o with_o rue_n myrrh_n frankincense_n and_o wax_v to_o move_v to_o stool_n which_o it_o perform_v as_o the_o last_o mention_v author_n say_v 12._o silvius_n use_v it_o in_o his_o carminative_a plaster_n to_o discuss_v wind_n which_o be_v rational_a
the_o say_a column_n three_o sort_n of_o dose_n the_o low_a on_o the_o left_a hand_n the_o high_a on_o the_o right_a hand_n and_o the_o moderate_a do_v between_o they_o as_o suppose_v you_o be_v about_o to_o give_v a_o middle_n do_v of_o the_o liquid_a panacea_fw-la to_o a_o strong_a man_n see_v for_o strong_a man_n in_o the_o upper_a space_n and_o for_o liquid_a panacea_fw-la in_o the_o first_o column_n on_o the_o left_a hand_n under_o the_o word_n opiate_n and_o where_o the_o column_n that_o belong_v to_o strong_a man_n and_o the_o space_n that_o belong_v to_o liquid_a panacea_fw-la do_v meet_v there_o you_o will_v find_v qt_n 20_o 30_o 40_o for_o the_o least_o middle_a and_o high_a do_v give_v which_o you_o think_v fit_a according_a to_o your_o intention_n so_o if_o you_o be_v about_o to_o give_v the_o high_a do_v of_o the_o solid_a panacea_fw-la to_o a_o strong_a woman_n you_o will_v find_v under_o the_o word_n strong_a woman_n over_o against_o solid_a panacea_fw-la gr_fw-la i_o gr_n i¼_n gr_n i_o ss_z which_o show_v you_o that_o gr_n i_o ss_z be_v the_o high_a do_v for_o a_o strong_a woman_n and_o so_o of_o all_o the_o rest_n 4._o note_v that_o i_o have_v be_v so_o cautious_a in_o dose_v all_o the_o opiate_n that_o you_o may_v very_o safe_o give_v the_o high_a dose_n to_o all_o but_o very_o weak_a person_n to_o who_o it_o be_v hardly_o fit_a to_o give_v any_o thing_n by_o reason_n of_o extreme_a weakness_n 5._o note_v that_o if_o you_o give_v any_o to_o young_a person_n under_o the_o age_n of_o 20._o you_o shall_v proportion_v the_o dose_n not_o so_o much_o as_o idle_a custom_n direct_v according_a to_o their_o year_n as_o bulk_n and_o strength_n for_o instance_n allow_v strong_a man_n to_o be_v 200_o pound_n weight_n you_o must_v give_v a_o strong_a youth_n of_o 100_o pound_v weight_n half_o the_o do_v of_o the_o strong_a man_n and_o so_o of_o all_o other_o only_o allow_v somewhat_o less_o the_o young_a they_o be_v because_o of_o the_o softness_n fineness_n or_o laxity_n of_o their_o texture_n especial_o if_o they_o be_v very_o young_a to_o who_o opiate_n must_v be_v cautious_o give_v or_o only_o diacodium_fw-la which_o be_v best_a in_o that_o case_n and_o that_o in_o a_o small_a proportion_n also_o for_o young_a child_n can_v bear_v opiate_n as_o well_o as_o grow_v person_n no_o not_o in_o proportion_n to_o their_o bulk_n or_o weight_n place_v this_o between_o p._n 294_o and_o p._n 295._o a_o table_n of_o the_o dose_n of_o the_o best_a and_o safe_a opiate_n opiate_n do_v do_v do_v do_v liquid_a to_o strong_a man_n to_o middling_a man_n &_o strong_a woman_n to_o weak_a man_n &_o middling_a woman_n to_o weak_a woman_n the_o liquid_a panacea_fw-la gt_fw-mi 20_o 30_o 40_o 16_o 23_o 30_o 12_o 18_o 24_o 10_o 15_o 20_o laudanum_n liquidum_fw-la cydoniatum_n gt_fw-fr 20_o 30_o 40_o 16_o 23_o 30_o 12_o 18_o 24_o 10_o 15_o 20_o sydenham_n laudanum_n gt_v 20_o 30_o 40_o 16_o 23_o 30_o 12_o 18_o 24_o 10_o 15_o 20_o diacodium_fw-la or_o syr._n e_fw-it mecon_fw-mi ☞_o i_o Ê’x_o ☞_o ss_z ☞_o ss_z Ê’vi_fw-la ☞_o i_o ☞_o ss_z Ê’v_o Ê’vi_fw-la Ê’iii_fw-la ☞_o ss_z Ê’v_v solid_n  _fw-fr  _fw-fr  _fw-fr  _fw-fr the_o solid_a panacea_fw-la gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ay_o i¼_n gr_n ss_z ¾_n i_o wedelius_n laudanum_n gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ay_o i¼_n gr_n ss_z ¾_n i_z le_fw-fr mort_n extract_n gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ay_o i¼_n gr_n ss_z ¾_n i_o dr._n bate_n pacific_a pill_n gr_n two_o iiss_n three_o gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ¾_n ay_o starkey_n or_o matthew_n pill_n gr_n vi_fw-la ix_o twelve_o gr_n v_o seven_o ix_o gr_n four_o vi_fw-la viij_o gr_n three_o four_o v_a philonium_fw-la romanum_fw-la Ê’ss_n ℈_o two_o Ê’i_fw-la ℈_o i_o Ê’ss_n ℈_o two_o gr_n xviii-xxiv_a Ê’ss_v gr_n xuj_o xx_o xxiv_o philonium_fw-la persicum_fw-la Ê’ss_n ℈_o two_o Ê’i_fw-la ℈_o i_o Ê’ss_o ℈_o two_o gr_n xviii-xxiv_a Ê’ss_v gr_n xuj_o xx_o xxiv_o venice_n treacle_n Ê’i_fw-it Ê’ii_fw-la Ê’iii_fw-la Ê’i_fw-la Ê’iss_v Ê’ii_fw-la ℈_o two_o Ê’i_fw-la ℈_o iiii_o Ê’ss_n ℈_o two_o Ê’i_fw-la mithridate_n ☞_o ss_z Ê’vi_fw-la ☞_o i_o Ê’iii_fw-la Ê’v_o Ê’vii_fw-la Ê’ii_fw-la ☞_o ss_z Ê’vi_fw-la Ê’ii_fw-la Ê’iii_fw-la ☞_o ss_z diascordium_fw-la ☞_o ss_z Ê’vi_fw-la ☞_o i_o Ê’iii_fw-la Ê’v_o Ê’vii_fw-la Ê’ii_fw-la ☞_o ss_z Ê’vi_fw-la Ê’ii_fw-la Ê’ii_fw-la ☞_o ss_z the_o dose_n of_o london_n laudanum_n which_o i_o mention_v rather_o for_o its_o general_a use_n than_o laudableness_n may_v be_v the_o same_o with_o that_o of_o the_o pacifick_n pill_n a_o table_n of_o mark_n very_o necessary_a for_o the_o better_a understanding_n of_o the_o table_n of_o dose_n gt_fw-fr signify_v a_o drop_n 〈◊〉_d signify_v a_o grain_n 〈◊〉_d signify_v a_o scruple_n which_o be_v 20_o grainâ—_n 〈◊〉_d or_o ☜_o signify_v a_o dram_n which_o be_v 3_o scruple_n 〈◊〉_d signify_v a_o ounce_n which_o be_v 8_o dramâ—_n or_o drachm_n â—_o â—_o signifieâ—_n a_o quarter_n of_o any_o to_n â—_o â—_o â—_o â—_o ss_z or_o ss_z signifieâ—_n half_a of_o any_o to_n â—_o â—_o signifieâ—_n 3_o quarter_n of_o any_o to_a chap._n xxviii_o the_o cure_n of_o the_o ill_a effect_n of_o opium_n have_v show_v how_o to_o prepare_v opium_n so_o as_o to_o render_v it_o safe_a and_o innocent_a in_o a_o moderate_a do_v and_o how_o much_o that_o moderate_a do_v be_v one_o may_v be_v apt_a to_o think_v that_o this_o chapter_n be_v needless_a but_o when_o you_o consider_v how_o many_o there_o be_v that_o may_v be_v negligent_a wilful_a want_v time_n skill_n etc._n etc._n to_o prepare_v it_o or_o take_v too_o much_o or_o too_o long_o of_o it_o and_o that_o the_o physician_n must_v be_v able_a to_o answer_n and_o remedy_n all_o ill_a accident_n that_o may_v happen_v you_o will_v find_v it_o very_o requisite_a that_o i_o shall_v show_v how_o to_o cure_v the_o ill_a effect_n of_o opium_n which_o proceed_v either_o 1._o from_o its_o rosin_n at_o stomach_n or_o 2._o from_o too_o much_o relaxation_n by_o a_o excessive_a do_v or_o 3._o from_o a_o long_a and_o lavish_a use_n of_o it_o or_o 4._o from_o a_o sudden_a leave_v it_o off_o after_o a_o long_a and_o lavish_a use_v thereof_o i._o to_o cure_v the_o ill_a effect_n of_o the_o rosin_n at_o stomach_n you_o be_v first_o to_o know_v whether_o that_o be_v the_o cause_n which_o you_o may_v learn_v 1._o by_o consider_v whether_o crude_a opium_n or_o some_o resinous_a preparation_n thereof_o be_v take_v especial_o by_o itself_o in_o the_o form_n of_o a_o pill_n or_o pill_n as_o a_o extract_v thereof_o out_o of_o spirit_n of_o wine_n or_o pilâ—e_a styrace_n or_o london_n laudanum_n or_o the_o like_a not_o due_o prepare_v as_o have_v be_v direct_v 2._o by_o the_o symptom_n which_o be_v these_o viz._n a_o nausea_n puke_v vomit_v hiccough_n convulsion_n distress_n and_o anxiety_n about_o the_o stomach_n particular_o the_o part_n call_v the_o pit_n of_o the_o stomach_n swimmings_n in_o the_o head_n vertigo_n palpitation_n and_o tremble_n of_o the_o heart_n agitation_n uneasiness_n a_o turbulent_a pulse_n and_o after_o a_o struggle_v of_o nature_n under_o those_o symptom_n faint_n leipothymy_n syncopes_fw-la etc._n etc._n which_o last_o you_o must_v not_o take_v for_o certain_a sign_n and_o symptom_n unless_o the_o former_a have_v precede_v they_o because_o it_o be_v not_o impossible_a but_o they_o may_v happen_v from_o the_o quantity_n of_o the_o opium_n condition_n or_o constitution_n of_o the_o person_n etc._n etc._n but_o this_o when_o all_o thing_n be_v compare_v together_o will_v be_v easy_o judge_v of_o especial_o if_o you_o observe_v 1._o whether_o those_o faint_n or_o leipothymy_n be_v not_o more_o like_o the_o failure_n and_o stupor_n of_o drunkard_n than_o bare_a faint_n if_o they_o be_v of_o the_o first_o sort_n then_o do_v they_o proceed_v from_o a_o over_o relaxation_n occasion_v by_o the_o opium_n and_o not_o from_o its_o rosin_n the_o cure_n of_o which_o belong_v to_o the_o second_o particular_a 2._o whether_o they_o be_v more_o attend_v with_o the_o sign_n of_o relaxation_n as_o deadness_n of_o the_o eye_n falter_v of_o the_o tongue_n darkness_n before_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la efflorescence_n of_o the_o skin_n laxity_n of_o the_o limb_n want_v of_o feel_v stupidity_n sleepiness_n failure_n of_o the_o sense_n or_o of_o make_v water_n loss_n of_o memory_n or_o understanding_n a_o dry_a mouth_n a_o slow_a and_o wide_a pulse_n and_o other_o thing_n much_o like_o the_o state_n of_o a_o deadish_a drunkenness_n for_o then_o those_o failure_n be_v the_o effect_n of_o relaxation_n by_o the_o pleasant_a sensation_n that_o the_o opium_n cause_n but_o after_o all_o it_o be_v the_o sort_n of_o opium_n that_o be_v take_v and_o