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then_o perhaps_o find_v they_o strong_a enough_o to_o pluck_v up_o the_o propose_a difficulty_n by_o the_o root_n but_o hold_v a_o minute_n or_o two_o have_v i_o not_o through_o haste_n or_o want_v of_o due_a circumspection_n run_v myself_o into_o the_o brier_n of_o a_o contradiction_n do_v i_o not_o in_o my_o last_o proposition_n affirm_v that_o the_o mediate_v cause_n of_o the_o natural_a motion_n of_o the_o heart_n differ_v in_o some_o respect_n from_o that_o by_o which_o all_o the_o rest_n of_o the_o muscle_n be_v incite_v and_o invigorate_v to_o voluntary_a motion_n and_o have_v i_o not_o in_o the_o paragraph_n immediate_o precede_v this_o say_v that_o the_o mediate_v cause_n both_o of_o the_o motion_n of_o the_o heart_n and_o of_o the_o motion_n of_o all_o other_o muscle_n be_v one_o and_o the_o same_o viz._n the_o succus_fw-la nervosus_fw-la derive_v from_o the_o brain_n where_o then_o be_v the_o difference_n presume_v i_o answer_v therefore_o that_o the_o difference_n lie_v 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former_a impediment_n be_v now_o at_o length_n free_a i_o come_v in_o the_o next_o place_n to_o establish_v the_o grand_a pillar_n upon_o which_o the_o whole_a weight_n of_o this_o my_o rude_a structure_n rely_v that_o be_v to_o make_v it_o appear_v to_o be_v not_o only_o possible_a but_o also_o probable_a that_o a_o few_o little_a drop_n of_o liquor_n instill_v into_o the_o fibre_n of_o the_o heart_n shall_v only_o by_o cause_v they_o to_o swell_v or_o by_o dilate_v their_o pore_n abbreviate_v they_o with_o a_o force_n great_a enough_o to_o make_v a_o constriction_n of_o the_o heart_n this_o if_o i_o shall_v be_v able_a to_o do_v i_o shall_v not_o despair_v of_o finish_v my_o building_n as_o i_o at_o first_o design_v for_o the_o remain_a part_n of_o my_o work_n will_v be_v little_a and_o easy_a as_o for_o the_o possibility_n of_o so_o great_a a_o effect_n from_o a_o cause_n that_o seem_v to_o be_v so_o weak_a and_o inconsiderable_a that_o may_v be_v without_o much_o difficulty_n prove_v from_o the_o just_a analogy_n or_o similitude_n of_o this_o effect_n to_o many_o other_o as_o great_a if_o not_o great_a effect_n common_o observe_v to_o arise_v from_o the_o like_a cause_n for_o mechanic_n example_n of_o this_o kind_n be_v every_o where_o so_o obvious_a to_o sense_n and_o so_o numerose_n that_o only_o to_o enumerate_v they_o will_v be_v a_o task_n hard_a and_o tediose_fw-la out_o of_o so_o vast_a a_o multitude_n therefore_o i_o will_v for_o brevitie_n sake_n select_a only_a two_o such_o as_o be_v not_o only_o pertinent_a and_o adequate_a to_o my_o subject_n but_o also_o in_o themselves_o eminent_o remarkable_a the_o first_o be_v of_o a_o new_a cable_n which_o upon_o wet_n will_v very_o much_o swell_v or_o become_v thick_a shrink_v and_o shorten_v itself_o beyond_o the_o belief_n of_o any_o but_o a_o mariner_n and_o galilaeus_fw-la have_v well_o observe_v this_o swell_a and_o
act_v continual_o but_o interrupt_o or_o per_fw-la vice_n short_a and_o almost_o isochronic_a or_o equal_a quiet_n interpose_v so_o that_o the_o blood_n express_v by_o the_o heart_n do_v not_o flow_v thence_o in_o a_o continue_a course_n as_o river_n and_o fountain_n do_v that_o be_v without_o intermission_n carry_v on_o by_o the_o weight_n of_o their_o water_n but_o gush_v forth_o and_o stop_v alternate_o though_o this_o vicissitude_n be_v exact_o regular_a and_o proceed_v in_o a_o constant_a order_n now_o these_o thing_n consider_v it_o may_v seem_v consentaneous_a to_o conclude_v that_o the_o motion_n of_o the_o blood_n can_v be_v continuus_fw-la since_o two_o pause_n or_o quiet_n be_v interpose_v betwixt_o every_o two_o pulsation_n or_o systole_n of_o the_o heart_n during_o each_o of_o which_o the_o motion_n cease_v but_o on_o the_o contrary_a aught_o to_o be_v esteem_v and_o call_v a_o interrupt_a and_o mix_v motion_n and_o yet_o notwithstanding_o the_o verisimilitude_n of_o this_o conclusion_n i_o doubt_v not_o to_o lay_v down_o and_o expose_v to_o your_o examination_n this_o first_o proposition_n that_o the_o blood_n be_v carry_v in_o a_o round_a through_o the_o body_n of_o a_o animal_n in_o a_o true_o continue_v and_o never_o interrupt_v motion_n this_o perhaps_o may_v sound_v like_o a_o paradox_n but_o that_o shall_v not_o a-whit_n discourage_v i_o from_o assert_v it_o while_o i_o remember_v that_o remarkable_a sentence_n of_o minutius_n felix_n in_o octavio_n inest_fw-la &_o in_fw-la incredibili_fw-la verum_fw-la &_o in_o verisimili_fw-la mendacium_fw-la though_o it_o be_v true_a and_o evident_a that_o the_o heart_n do_v not_o in_o the_o time_n of_o its_o pause_n express_v any_o blood_n into_o the_o artery_n yet_o it_o be_v not_o true_a that_o the_o blood_n contain_v in_o the_o artery_n in_o the_o viscera_n in_o the_o habit_n of_o the_o body_n and_o in_o the_o vein_n do_v at_o the_o same_o time_n stagnate_n and_o stop_v its_o course_n but_o on_o the_o 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all_o the_o muscle_n of_o the_o body_n from_o the_o observation_n of_o this_o vulgar_a phaenomenon_n viz._n the_o emptiness_n of_o the_o artery_n in_o dead_a body_n the_o ancient_n perhaps_o take_v occasion_n to_o believe_v and_o teach_v that_o not_o blood_n but_o only_o vital_a spirit_n be_v contain_v in_o the_o artery_n second_o this_o appear_v also_o in_o the_o vein_n for_o that_o the_o blood_n do_v continual_o flow_v on_o in_o they_o likewise_o not_o only_a when_o it_o be_v urge_v forward_o by_o the_o arterial_a blood_n pursue_v it_o but_o even_o in_o the_o time_n of_o the_o heart_n pause_n be_v evince_v from_o this_o that_o then_o the_o blood_n run_v on_o through_o the_o trunk_n of_o the_o vena_fw-la cava_fw-la to_o replenish_v the_o right_a ventricle_n of_o the_o heart_n but_o why_o do_v i_o misspend_v time_n in_o allege_v reason_n to_o prove_v a_o truth_n that_o be_v manifest_a to_o sense_n in_o phlebotomy_n no_o soon_o be_v a_o vein_n open_v than_o the_o blood_n flow_v forth_o 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circular_a course_n be_v emit_v immediate_o out_o of_o the_o artery_n into_o the_o vein_n these_o vessel_n be_v separate_a and_o though_o we_o opine_n that_o there_o be_v some_o secret_a communication_n betwixt_o the_o extreme_a orifice_n of_o the_o artery_n and_o those_o of_o the_o capillary_a vein_n by_o the_o intermediate_v spongy_a substance_n of_o the_o flesh_n viscera_n and_o glandule_n or_o by_o the_o cribrose_n substance_n of_o the_o bone_n as_o by_o the_o pore_n of_o a_o pumice_n stone_n yet_o we_o be_v still_o to_o seek_v by_o what_o motive_n force_v the_o blood_n may_v be_v carry_v on_o from_o those_o intermediate_v porosity_n and_o insinuate_v into_o the_o vein_n first_o because_o it_o be_v consentaneous_a that_o the_o impulsive_a force_n whereby_o the_o systole_n of_o the_o heart_n squirt_n the_o blood_n into_o the_o artery_n be_v by_o degree_n weaken_v and_o at_o length_n languid_a in_o those_o straits_n of_o the_o extreme_a vessel_n and_o of_o the_o intermediate_v 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from_o hence_o that_o in_o the_o brain_n in_o the_o medullary_a substance_n of_o the_o bone_n where_o no_o compression_n can_v be_v admit_v the_o capillary_a vein_n receive_v the_o blood_n as_o free_o as_o in_o the_o soft_a flesh_n itself_o see_v then_o that_o the_o effect_n can_v be_v deny_v viz._n that_o all_o the_o blood_n effuse_v out_o of_o the_o artery_n be_v after_o absorb_v and_o carry_v off_o by_o the_o vein_n to_o be_v bring_v back_o again_o into_o the_o heart_n and_o see_v also_o that_o this_o be_v not_o effect_v by_o way_n of_o attraction_n there_o be_v no_o such_o thing_n as_o attraction_n in_o nature_n as_o i_o have_v more_o than_o once_o elsewhere_o prove_v we_o be_v compel_v to_o assert_v that_o the_o blood_n be_v imbibe_v by_o the_o capillary_a vein_n for_o the_o same_o reason_n and_o by_o the_o same_o mechanic_n action_n by_o which_o syphon_n sponge_n filtre_n chord_n and_o all_o porose_a body_n be_v penetrate_v by_o water_n with_o which_o they_o be_v moisten_v which_o power_n be_v no_o other_o than_o the_o gravity_n of_o the_o fluid_n itself_o which_o be_v augment_v by_o the_o impetus_fw-la of_o its_o proper_a motion_n and_o by_o the_o impulse_n communicate_v to_o it_o from_o external_a force_n so_o the_o motive_n force_n of_o gravity_n which_o the_o blood_n can_v want_v no_o more_o than_o water_n can_v when_o it_o find_v the_o small_a channel_n of_o the_o capillary_a vein_n open_a for_o they_o can_v never_o be_v so_o close_o constringe_v by_o the_o flag_a and_o connivency_n of_o their_o thin_a membrane_n as_o to_o leave_v no_o entrance_n for_o a_o fluid_a as_o appear_v in_o the_o pore_n of_o rope_n how_o hard_o soever_o twist_v must_v of_o necessity_n overcome_v the_o weak_a resistance_n of_o the_o straits_n in_o all_o filtre_n and_o porose_a body_n and_o consequent_o the_o blood_n may_v be_v insinuate_v into_o the_o capillary_a vein_n by_o a_o mechanic_n action_n like_o that_o of_o filtration_n if_o this_o proposition_n
of_o the_o muscle_n of_o the_o gut_n stomach_n tendon_n membrane_n and_o the_o like_a fibrose_n part_n natural_o resist_v distraction_n and_o have_v a_o power_n of_o contract_v themselves_o after_o extension_n yea_o more_o we_o see_v that_o all_o fibres_fw-fr even_o in_o their_o natural_a posture_n be_v somewhat_o upon_o the_o stretch_n for_o when_o they_o be_v cut_v they_o instant_o shorten_v themselves_o towards_o both_o end_n which_o will_v not_o happen_v if_o they_o have_v be_v constitute_v in_o a_o middle_a state_n betwixt_o laxity_n and_o extension_n as_o a_o bow_n unbend_v be_v quiet_a suffer_v neither_o contraction_n nor_o distraction_n of_o its_o part_n now_o if_o all_o fibre_n even_o in_o their_o natural_a state_n suffer_v some_o degree_n of_o stretch_v certain_o when_o the_o artery_n be_v replenish_v with_o blood_n their_o cavity_n must_v be_v dilate_v and_o in_o the_o dilatation_n of_o their_o cavity_n their_o transverse_n or_o circular_a fibre_n must_v suffer_v much_o 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of_o the_o distend_v artery_n be_v the_o cause_n of_o the_o expulsion_n of_o the_o blood_n out_o of_o they_o into_o the_o substance_n of_o the_o part_n contrary_a to_o their_o opinion_n who_o ascribe_v this_o expulsion_n only_o to_o the_o systole_n of_o the_o heart_n ¶_o ⸪_o the_o natural_a method_n of_o acquire_a science_n you_o know_v be_v to_o begin_v from_o thing_n more_o know_v and_o then_o to_o advance_v to_o thing_n less_o know_v to_o proceed_v from_o effect_n to_o their_o cause_n see_v therefore_o that_o we_o be_v now_o certain_a that_o the_o blood_n in_o animal_n be_v carry_v by_o a_o perpetual_a circular_a motion_n through_o all_o part_n of_o the_o body_n our_o next_o business_n be_v to_o inquire_v what_o be_v the_o cause_n of_o this_o admirable_a motion_n as_o well_o the_o final_a as_o the_o efficient_a i_o begin_v from_o the_o final_a it_o be_v a_o question_n worthy_a our_o consideration_n why_o or_o to_o what_o end_n nature_n all_o who_o counsel_n and_o action_n be_v ordain_v by_o a_o infinite_a wisdom_n have_v institute_v this_o rapid_a circulation_n of_o the_o blood_n constant_a it_o be_v even_o from_o common_a experience_n that_o whenever_o the_o blood_n be_v quiet_a or_o cease_v from_o motion_n whether_o within_o or_o without_o the_o body_n of_o a_o animal_n the_o red_a and_o grumose_n part_v of_o it_o soon_o curdle_n and_o be_v separate_v from_o the_o serose_n or_o albumen_n and_o so_o the_o constitution_n or_o contexture_n of_o it_o be_v dissolve_v and_o corrupt_v whereas_o on_o the_o contrary_a while_o the_o blood_n continue_v in_o perpetual_a motion_n within_o its_o vessel_n in_o the_o body_n of_o a_o live_a animal_n so_o long_o the_o ordinate_a mixture_n of_o its_o element_n due_a temper_n and_o vital_a constitution_n of_o it_o be_v conserve_v for_o mechanical_a reason_n in_o our_o ensue_a discourse_n to_o be_v explain_v it_o seem_v then_o that_o such_o a_o mixture_n of_o the_o constituent_a part_n of_o the_o blood_n upon_o which_o the_o vitality_n of_o it_o do_v necessary_o depend_v can_v be_v otherwise_o conserve_v than_o by_o a_o continual_a agitation_n and_o concussion_n make_v in_o the_o vessel_n first_o by_o the_o heart_n with_o strong_a force_n impel_v the_o blood_n through_o the_o artery_n then_o that_o impulsive_a force_n languish_v by_o filtration_n in_o the_o space_n intermediate_v betwixt_o the_o artery_n and_o vein_n next_o in_o the_o vein_n by_o the_o constriction_n of_o their_o circular_a fibre_n by_o the_o compression_n of_o the_o muscle_n and_o the_o viscera_n and_o the_o inspire_a air_n all_o which_o compression_n will_v not_o suffice_v be_v not_o valve_n place_v commodious_o within_o the_o vein_n by_o which_o the_o motion_n of_o the_o blood_n be_v accelerate_a and_o a_o far_a conquassation_n of_o it_o make_v and_o here_o we_o meet_v with_o a_o fair_a occasion_n to_o reflect_v upon_o the_o mutual_a anastomôse_n of_o the_o capillary_a vein_n and_o the_o infrequent_a distribution_n of_o valve_n in_o one_o and_o the_o same_o vein_n for_o both_o these_o contribute_v also_o their_o proportion_n towards_o the_o end_n now_o under_o our_o disquisition_n for_o the_o texture_n of_o the_o vein_n be_v indeed_o lax_n and_o soft_a yet_o such_o as_o may_v by_o virtue_n of_o their_o circular_a fibre_n be_v constringe_v and_o contract_v hence_o it_o be_v that_o by_o the_o blood_n regurgitate_v in_o those_o tract_n of_o the_o vein_n that_o have_v no_o valve_n by_o the_o great_a quantity_n and_o force_n of_o its_o regurgitation_n or_o recoil_n the_o low_a part_n of_o the_o vein_n be_v much_o dilate_v and_o on_o the_o contrary_a the_o high_a part_n be_v contract_v so_o that_o the_o blood_n be_v by_o this_o reflux_n though_o inobservable_a agitate_a and_o conquassated_a may_v revive_v its_o due_a commistion_n and_o conserve_v its_o vital_a constitution_n it_o appear_v then_o the_o defect_n of_o valve_n also_o have_v its_o use_n within_o the_o cavity_n of_o the_o artery_n as_o i_o say_v before_o no_o valve_n be_v place_v because_o the_o grand_a force_n by_o which_o the_o blood_n be_v impel_v through_o they_o be_v more_o than_o sufficient_a to_o conquassate_fw-it and_o commix_v it_o by_o wedge_v in_o as_o it_o be_v the_o more_o fluid_a albugineous_a particle_n among_o the_o red_a grumose_n particle_n that_o from_o both_o sort_n commix_v per_fw-la minimas_fw-la moleculas_fw-la as_o they_o say_v and_o yet_o mutual_o reluctant_a the_o vital_a mication_n or_o oscillatory_n intestine_a motion_n of_o the_o blood_n may_v be_v continue_v so_o then_o here_o be_v neither_o need_n of_o nor_o place_n for_o a_o fermentation_n now_o from_o the_o consideration_n of_o these_o thing_n premise_v i_o conclude_v that_o the_o circulation_n of_o the_o blood_n be_v institute_v for_o the_o conservation_n of_o its_o requisite_a temper_n and_o vital_a constitution_n which_o be_v to_o be_v inquire_v and_o which_o lead_v we_o to_o the_o admirable_a effect_n and_o benefit_n arise_v to_o the_o animal_n oeconomy_n from_o the_o same_o velocity_n of_o the_o circulation_n of_o the_o blood_n which_o be_v certain_o so_o great_a that_o the_o whole_a mass_n of_o blood_n run_v its_o circular_a race_n in_o the_o twenty_o part_n of_o a_o hour_n or_o thereabouts_o even_o in_o a_o sedentary_a and_o sedate_v man_n as_o have_v by_o many_o be_v demonstrate_v from_o the_o quantity_n of_o blood_n common_o contain_v in_o the_o body_n from_o the_o number_n of_o pulse_n make_v in_o a_o hour_n and_o from_o the_o quantity_n of_o blood_n express_v by_o every_o pulse_n of_o the_o heart_n and_o we_o have_v already_o see_v what_o advantage_n redound_v to_o the_o blood_n itself_o from_o this_o velocity_n our_o curiosity_n spur_v we_o on_o to_o inquire_v also_o what_o other_o scope_n or_o end_n nature_n may_v probable_o be_v conceive_v to_o have_v propose_v to_o herself_o when_o she_o institute_v this_o so_o rapid_a motion_n or_o what_o emolument_n and_o benefit_n from_o thence_o redound_v to_o the_o oeconomy_n of_o the_o whole_a body_n of_o these_o the_o first_o seem_v to_o be_v this_o that_o in_o every_o pulsation_n of_o the_o heart_n a_o great_a quantity_n of_o blood_n be_v effuse_v and_o protrude_v out_o of_o the_o capillary_a artery_n into_o the_o habit_n of_o the_o part_n for_o their_o refocillation_n by_o influent_a life_n of_o which_o i_o have_v former_o discourse_v copiose_o in_o this_o place_n for_o by_o how_o much_o swift_a the_o motion_n of_o any_o liquor_n or_o other_o fluid_a through_o a_o pipe_n or_o canal_n be_v so_o much_o a_o great_a quantity_n of_o it_o be_v in_o equal_a time_n effuse_v at_o the_o orifice_n thereof_o as_o have_v be_v ingenious_o demonstrate_v by_o b._n castellus_n fluxu_fw-la and_o therefore_o the_o blood_n be_v like_o a_o full_a and_o rapid_a torrent_n impel_v into_o the_o pore_n of_o the_o flesh_n and_o viscera_n the_o second_o be_v the_o energy_n of_o the_o stroke_n with_o which_o the_o blood_n project_v by_o the_o heart_n dash_v against_o the_o same_o extreme_a part_n which_o energy_n be_v
carry_v on_o the_o resemblance_n a_o little_a far_o i_o soon_o discover_v the_o disparity_n to_o be_v so_o many_o and_o so_o great_a that_o it_o be_v impossible_a to_o reconcile_v they_o into_o a_o just_a analogy_n whereupon_o condemn_v the_o extravagance_n of_o my_o fancy_n i_o sober_o conclude_v that_o the_o heart_n of_o a_o animal_n be_v a_o engine_n never_o to_o be_v imitate_v by_o human_a art_n and_o i_o find_v myself_o more_o incline_v to_o applaud_v the_o judgement_n of_o that_o prodigy_n of_o mathematical_a knowledge_n archimedes_n of_o syracuse_n for_o never_o attempt_v to_o counterfeit_v the_o motion_n of_o the_o heart_n than_o to_o admire_v his_o wit_n show_v in_o make_v a_o sphere_n of_o glass_n athan._n 1._o kircher_n deny_v that_o any_o part_n of_o it_o be_v glass_n but_o only_o the_o outside_n that_o man_n may_v discern_v the_o wheel_n and_o motion_n within_o which_o represent_v the_o perfect_a order_n and_o motion_n of_o the_o celestial_a body_n and_o which_o claudian_n 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the_o first_o therefore_o viz._n the_o admirable_a motive_n force_v of_o the_o heart_n since_o the_o round_a and_o conical_a figure_n of_o the_o heart_n do_v not_o permit_v we_o to_o attempt_v the_o measure_n of_o its_o motive_n power_n by_o the_o same_o way_n by_o which_o the_o most_o learned_a alphonsus_n borellus_n have_v with_o singular_a sagacity_n measure_v the_o force_n of_o very_a many_o other_o muscle_n of_o man_n body_n namely_o by_o weight_n suspend_v by_o they_o and_o since_o therefore_o in_o this_o disquisition_n we_o can_v from_o the_o effect_n proceed_v to_o the_o knowledge_n of_o the_o cause_n we_o be_v compel_v from_o some_o other_o sign_n to_o raise_v a_o probable_a conjecture_n whence_o we_o may_v investigate_v the_o greatness_n of_o the_o effect_n and_o this_o sign_n shall_v be_v the_o similitude_n and_o analogy_n which_o the_o muscule_n of_o the_o heart_n seem_v to_o hold_v to_o other_o muscle_n of_o the_o same_o animal_n let_v we_o then_o with_o the_o same_o 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those_o two_o muscle_n we_o may_v probable_o infer_v that_o the_o motive_n force_n of_o the_o heart_n be_v equal_a to_o that_o which_o those_o two_o muscle_n shut_v the_o mandible_a exercise_n now_o because_o no_o entire_a fiber_n of_o these_o two_o muscle_n be_v less_o than_o two_o inch_n long_a take_v all_o the_o fibres_fw-fr one_o with_o another_o that_o the_o excess_n of_o the_o long_a may_v compensate_a the_o defect_n of_o the_o short_a and_o because_o in_o a_o inch_n space_n of_o every_o single_a fiber_n we_o may_v imagine_v more_o than_o twenty_o little_a machine_n or_o rhomboid_a pore_n contain_v like_o the_o link_n of_o a_o chain_n in_o a_o watch_n or_o the_o mesh_n of_o a_o net_n in_o a_o row_n one_o above_o another_o let_v we_o notwithstanding_o suppose_v no_o more_o than_o ten_o small_a fibre_n to_o be_v contain_v in_o that_o space_n therefore_o in_o the_o length_n of_o every_o one_o of_o the_o fibre_n that_o compose_v the_o say_v two_o muscle_n there_o will_v be_v 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quod_fw-la erat_fw-la demonstrandum_fw-la and_o thus_o have_v i_o give_v you_o a_o summary_n of_o what_o borellus_n have_v from_o a_o long_a chain_n of_o most_o ingeniose_fw-la proposition_n and_o theorem_n in_o fine_a infer_v i_o come_v therefore_o to_o the._n second_o and_o last_o considerable_a propose_v to_o be_v inquire_v viz._n the_o efficient_a cause_n of_o this_o so_o wonderful_a motive_n force_v of_o the_o heart_n these_o seem_v to_o be_v no_o more_o than_o two_o of_o which_o one_o be_v immediate_a the_o other_o mediate_v as_o to_o the_o the_o former_a viz._n the_o immediate_a cause_n of_o the_o heart_n motive_n power_n we_o be_v not_o to_o expect_v to_o learn_v either_o what_o it_o be_v or_o whence_o it_o proceed_v from_o the_o doctrine_n of_o the_o ancient_n for_o they_o have_v observe_v that_o the_o heart_n be_v not_o as_o all_o the_o other_o muscle_n of_o the_o body_n be_v move_v ad_fw-la arbitrium_fw-la voluntatis_fw-la at_o the_o command_n of_o the_o will_n not_o only_o name_v the_o motion_n of_o those_o voluntary_a and_o the_o motion_n of_o this_o natural_a as_o they_o have_v good_a reason_n to_o do_v but_o also_o conceive_v and_o teach_v the_o cause_n of_o the_o motion_n of_o the_o heart_n to_o be_v divers_a from_o the_o cause_n of_o the_o motion_n of_o the_o rest_n of_o the_o muscle_n and_o according_o constitute_v and_o assign_v to_o the_o heart_n a_o certain_a blind_a and_o unintelligible_a pulsifick_a faculty_n whereto_o alone_o they_o ascribe_v as_o well_o the_o diastole_n as_o the_o systole_n thereof_o which_o they_o have_v no_o just_a reason_n to_o do_v to_o evince_v this_o their_o palpable_a error_n i_o will_v assert_v this_o proposition_n that_o the_o immediate_a motive_n cause_n of_o the_o heart_n be_v the_o very_a same_o with_o that_o by_o which_o the_o muscle_n of_o the_o limb_n be_v move_v voluntary_o first_o it_o be_v most_o evident_a to_o sense_n that_o
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cavity_n of_o the_o nerve_n annex_v to_o the_o heart_n may_v remain_v still_o full_a of_o and_o turgid_a with_o the_o roscid_n succus_fw-la nervosus_fw-la which_o be_v hinder_v from_o regress_n by_o their_o spontaneous_a contraction_n towards_o the_o heart_n and_o keep_v in_o a_o state_n of_o fluxility_n by_o the_o yet_o last_a warmth_n of_o the_o heart_n may_v for_o some_o time_n be_v instill_v into_o the_o fibre_n of_o it_o and_o by_o swell_v of_o they_o cause_n they_o to_o constringe_v the_o ventricles_n as_o before_o then_o the_o heart_n be_v irritate_v by_o the_o prick_n of_o a_o needle_n or_o some_o sharp_a and_o pungent_a liquor_n may_v be_v able_a by_o its_o peristaltic_a constriction_n to_o squeeze_v out_o the_o few_o remain_a drop_n of_o the_o roscid_a liquor_n which_o be_v do_v the_o pulsation_n cease_v for_o ever_o to_o the_o blood_n this_o effect_n ought_v not_o to_o be_v ascribe_v for_o after_o all_o relic_n of_o it_o have_v be_v with_o warm_a water_n and_o a_o syringe_n wash_v out_o of_o the_o ventricles_n and_o squeeze_v out_o of_o the_o vessel_n the_o pulsation_n notwithstanding_o will_v continue_v for_o sometime_o nor_o can_v it_o be_v with_o more_o reason_n ascribe_v to_o convulsion_n of_o the_o heart_n because_o all_o convulsion_n be_v disorderly_a and_o unequal_a both_o in_o the_o time_n of_o their_o gird_n and_o in_o those_o of_o their_o intermission_n whereas_o in_o this_o case_n the_o pulsation_n be_v regular_a and_o isochronical_a with_o equal_a pause_n nor_o to_o the_o heat_v communicate_v by_o the_o blood_n to_o the_o heart_n before_o it_o be_v exsect_v and_o not_o yet_o quite_o extinct_a because_o that_o borrow_a heat_n soon_o vanish_v and_o no_o external_a heat_n will_v revive_v the_o languish_a pulsation_n after_o all_o the_o roscid_a juice_n have_v be_v express_v out_o of_o the_o end_n of_o the_o nerve_n leave_v in_o the_o heart_n nothing_o then_o remain_v to_o solve_v this_o phaenomenon_n but_o the_o instillation_n of_o a_o few_o drop_n of_o our_o roscid_a liquor_n into_o the_o fibre_n of_o the_o heart_n to_o swell_v they_o and_o so_o urge_v they_o to_o constriction_n of_o the_o ventricles_n the_o other_o difficulty_n be_v this_o why_o be_v there_o not_o a_o pulsation_n after_o the_o same_o manner_n also_o in_o all_o the_o muscle_n of_o the_o limb_n since_o their_o fibre_n be_v of_o the_o same_o nature_n in_o all_o thing_n their_o disposition_n and_o direction_n only_o except_v since_o the_o orifice_n of_o the_o nerve_n pertain_v to_o they_o be_v in_o the_o brain_n as_o open_a to_o admit_v and_o imbibe_n the_o succus_fw-la nervosus_fw-la there_o elaborate_a and_o provide_v for_o they_o and_o since_o the_o same_o nerve_n be_v equal_o spungy_a and_o permeable_a in_o their_o constitution_n and_o so_o apt_a to_o transfer_v that_o liquor_n as_o the_o orifice_n of_o the_o cardiac_n nerve_n be_v to_o receive_v or_o their_o canales_n to_o transfer_v it_o if_o the_o whole_a apparatus_n be_v the_o same_o on_o both_o part_n whence_o come_v it_o that_o the_o same_o effect_n be_v not_o produce_v in_o both_o at_o this_o goliath_n i_o have_v in_o my_o scrip_n three_o pebble_n to_o throw_v and_o though_o my_o arm_n be_v weak_a i_o will_v not_o despair_v of_o hit_v he_o in_o the_o forehead_n first_o therefore_o i_o say_v that_o it_o be_v not_o yet_o certain_o know_v to_o any_o mortal_a man_n by_o what_o mediate_a cause_n the_o muscle_n of_o the_o limb_n be_v move_v at_o the_o command_n of_o the_o will_n whether_o by_o simple_a contraction_n of_o the_o original_n of_o the_o nerve_n insert_v into_o they_o or_o by_o the_o immission_n of_o the_o succus_fw-la nervosus_fw-la more_o copiose_o and_o swift_o at_o the_o time_n of_o their_o be_v put_v into_o action_n though_o the_o mechanism_n of_o their_o fibre_n make_v it_o more_o probable_a that_o they_o be_v move_v by_o immission_n of_o some_o liquor_n from_o the_o brain_n by_o which_o the_o rhomboid_a mesh_n or_o pore_n of_o their_o fibre_n be_v all_o at_o the_o same_o time_n swell_v and_o dilate_v a_o contraction_n of_o the_o whole_a muscle_n must_v in_o the_o same_o moment_n be_v effect_v and_o therefore_o i_o prefer_v this_o opinion_n to_o the_o former_a and_o have_v follow_v it_o in_o many_o place_n of_o this_o rude_a discourse_n but_o yet_o this_o opinion_n have_v not_o lead_v i_o to_o a_o discovery_n of_o the_o cause_n of_o the_o difference_n this_o present_a difficulty_n compel_v i_o to_o hunt_v after_o shall_v i_o imagine_v valve_n affix_v by_o nature_n to_o the_o orifice_n of_o the_o nerve_n of_o the_o muscle_n as_o mons_fw-la des_n cartes_n do_v in_o the_o body_n of_o they_o though_o such_o a_o artifice_n be_v not_o impossible_a yet_o beside_o that_o no_o such_o valve_n have_v hitherto_o be_v find_v in_o the_o brain_n i_o shall_v still_o be_v to_o seek_v for_o a_o cause_n to_o open_v and_o shut_v they_o ad_fw-la arbitrium_fw-la voluntatis_fw-la and_o so_o shall_v be_v put_v to_o a_o stand_n in_o my_o disquisition_n which_o to_o 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use_v a_o great_a portion_n of_o the_o same_o invigorate_n liquor_n viz._n so_o much_o as_o be_v requisite_a to_o swell_v they_o up_o by_o replenish_n their_o pore_n and_o force_v they_o to_o contraction_n which_o be_v the_o common_a action_n of_o all_o muscle_n on_o the_o other_o part_n let_v it_o be_v suppose_v that_o in_o the_o brain_n nature_n have_v frame_v the_o original_n of_o the_o cardiac_n nerve_n by_o a_o different_a artifice_n namely_o such_o as_o that_o not_o only_o their_o orifice_n may_v always_o be_v open_a to_o imbibe_n but_o also_o their_o canales_n so_o easy_o pervious_a to_o transmit_v the_o roscid_a liquor_n as_o that_o without_o any_o vellication_n without_o any_o convulsive_a motion_n the_o same_o liquor_n may_v mere_o by_o the_o plenitude_n of_o the_o canales_n themselves_o be_v effuse_v guttulatim_fw-la into_o the_o fibre_n of_o the_o heart_n to_o cause_v the_o alternate_a constriction_n or_o pulsation_n of_o it_o and_o it_o be_v the_o more_o lawful_a for_o i_o to_o suppose_v this_o difference_n of_o structure_n in_o nerve_n ordain_v for_o different_a use_n because_o it_o be_v above_o all_o doubt_n that_o the_o optic_a nerve_n have_v a_o peculiar_a fabric_n and_o contexture_n wherein_o they_o differ_v from_o the_o auditory_a and_o all_o other_o nerve_n inservient_fw-la to_o the_o rest_n of_o the_o external_a sense_n and_o that_o the_o organ_n of_o every_o sense_n have_v its_o nerve_n of_o a_o peculiar_a constitution_n accommodate_v to_o the_o nature_n of_o its_o proper_a object_n though_o those_o difference_n consist_v in_o such_o minute_n and_o subtle_a artifices_fw-la as_o have_v hitherto_o elude_v our_o most_o curiose_fw-la research_v though_o assist_v by_o the_o best_a sort_n of_o microscope_n why_o then_o may_v it_o not_o be_v think_v that_o nature_n have_v give_v to_o the_o cardiac_n nerve_n also_o a_o constitution_n divers_a from_o that_o of_o all_o
see_v that_o the_o liquor_n find_v in_o the_o pericardium_n be_v easy_o capable_a of_o coagulation_n either_o by_o heat_n or_o cold_a so_o as_o to_o become_v like_o jelly_n of_o hartshorn_n or_o the_o white_a of_o a_o egg_n harden_v by_o boil_v as_o the_o serum_fw-la of_o the_o blood_n will_v do_v and_o observe_v the_o various_a little_a gland_n seat_v about_o the_o basis_n of_o the_o heart_n for_o which_o i_o can_v find_v no_o other_o equal_o probable_a use_n as_o to_o instil_v the_o serum_fw-la into_o the_o pericardium_n to_o facilitate_v the_o motion_n of_o the_o heart_n which_o most_o certain_o that_o liquor_n do_v as_o the_o humour_n instill_v out_o of_o the_o glandulae_fw-la lacrymale_n upon_o the_o outside_n of_o the_o eye_n serve_v to_o moisten_v and_o make_v they_o more_o easy_o movable_a every_o way_n when_o i_o have_v i_o say_v observe_v and_o consider_v these_o thing_n i_o reject_v that_o thought_n and_o embrace_v this_o of_o the_o absorption_n of_o the_o relic_n of_o the_o succus_fw-la nervosus_fw-la by_o the_o vein_n of_o the_o heart_n the_o second_o be_v that_o the_o diastole_n of_o the_o heart_n be_v cause_v partly_o by_o the_o relaxation_n of_o the_o fibre_n of_o it_o spontaneous_o restore_v themselves_o to_o their_o natural_a posture_n and_o length_n as_o all_o other_o tensile_n body_n be_v wont_a to_o do_v after_o they_o have_v be_v distend_v partly_o by_o the_o force_n of_o the_o blood_n rush_v out_o of_o the_o ear_n into_o the_o ventricles_n of_o the_o heart_n and_o replenish_n they_o wherefore_o the_o wisdom_n of_o nature_n be_v admirable_a also_o in_o this_o that_o she_o ordain_v these_o two_o cause_n of_o the_o diastole_n viz._n the_o relaxation_n of_o the_o fibre_n and_o the_o influx_n of_o the_o blood_n into_o the_o ventricles_n to_o be_v exact_o coincident_a that_o with_o unite_a force_n they_o may_v cooperate_v more_o efficacious_o whence_o it_o appear_v that_o in_o the_o diastole_n the_o heart_n be_v not_o whole_o passive_a as_o all_o anatomist_n hitherto_o have_v believe_v it_o to_o be_v for_o unless_o the_o fibres_n do_v restore_v themselves_o to_o their_o former_a longitude_n which_o be_v a_o natural_a action_n at_o the_o same_o time_n the_o influx_n of_o the_o blood_n happen_v certain_o there_o can_v be_v no_o room_n to_o receive_v the_o blood_n because_o the_o inside_n of_o the_o ventricles_n will_v continue_v to_o touch_v each_o the_o other_o and_o so_o there_o can_v be_v no_o diastole_n the_o three_o and_o last_o be_v that_o it_o appear_v from_o the_o whole_a series_n of_o this_o discourse_n that_o the_o pulsation_n or_o constriction_n of_o the_o heart_n have_v its_o force_n from_o that_o mechanic_n power_n which_o be_v call_v the_o wedge_n and_o that_o the_o blood_n be_v express_v out_o of_o the_o heart_n by_o virtue_n of_o another_o mechanic_n power_n which_o be_v name_v the_o praelum_fw-la or_o press_n and_o consequent_o that_o the_o heart_n itself_o be_v as_o all_o automata_n be_v move_v not_o by_o spirit_n nor_o by_o a_o pulsifick_a faculty_n nor_o by_o rarefaction_n of_o the_o blood_n nor_o ebullition_n or_o fermentation_n of_o the_o blood_n nor_o by_o explosion_n of_o saline_n and_o acid_n spirituose_fw-la liquor_n but_o by_o mechanic_n necessity_n which_o from_o the_o beginning_n i_o hope_v i_o shall_v be_v able_a fair_o to_o prove_v if_o the_o success_n of_o my_o endeavour_n have_v not_o be_v answerable_a to_o that_o hope_n i_o will_v not_o go_v about_o to_o extenuate_v the_o blame_n of_o my_o faileur_n by_o cite_v example_n of_o much_o great_a wit_n which_o have_v before_o i_o in_o vain_a attempt_v to_o reveal_v the_o same_o secret_a of_o nature_n but_o consolate_v myself_o with_o this_o that_o my_o judge_n be_v man_n no_o less_o belove_v for_o their_o exemplary_a candour_n and_o humanity_n than_o honour_v for_o their_o excellency_n in_o all_o kind_n of_o learning_n and_o who_o need_v not_o be_v put_v in_o mind_n that_o truth_n be_v a_o tree_n who_o root_n be_v in_o heaven_n and_o of_o which_o even_o the_o wise_a of_o we_o dim-sighted_a mortal_n here_o upon_o earth_n see_v nothing_o but_o the_o shadow_n of_o its_o branch_n i_o will_v therefore_o conclude_v this_o inelaborate_a disquisition_n with_o that_o memorable_a say_n of_o the_o prince_n of_o roman_a orator_n consolation_n de_n his_o statuat_fw-la unusquisque_fw-la ut_fw-la libet_fw-la quid_fw-la autem_fw-la verius_fw-la sit_fw-la deus_fw-la ipse_fw-la viderit_fw-la hominem_fw-la quidem_fw-la scire_fw-la arbitror_fw-la neminem_fw-la ¶_o ⸫_o my_o lecture_n such_o as_o they_o be_v much_o honour_a auditor_n you_o have_v with_o oblige_a patience_n hear_v be_v please_v i_o beseech_v you_o to_o hear_v also_o before_o you_o rise_v a_o word_n which_o i_o have_v to_o speak_v in_o my_o own_o defence_n be_v it_o not_o indecent_a to_o compare_v small_a thing_n with_o great_a i_o shall_v venture_v perhaps_o to_o advertise_v you_o that_o the_o reason_n which_o induce_v i_o to_o attempt_v a_o reformation_n of_o the_o borellian_a hypothesis_n of_o the_o motion_n of_o the_o heart_n which_o doctor_n harvey_n himself_o call_v the_o sun_n of_o the_o microcosm_n sanguine_a seem_v to_o have_v some_o kind_n of_o analogy_n to_o those_o which_o move_v the_o prince_n of_o astronomer_n tycho_n brahe_n to_o dislike_v the_o ptolemaic_a system_n of_o the_o macrocosm_n or_o great_a world_n and_o to_o excogitate_v a_o new_a one_o of_o more_o probability_n and_o neatness_n for_o as_o tycho_n animadvert_v that_o the_o celestial_a orb_n have_v be_v by_o ptolemy_n distribute_v unhansom_o that_o so_o many_o and_o so_o great_a epicycle_n be_v in_o vain_a imagine_v to_o explicate_v the_o retrogradation_n of_o the_o planet_n and_o their_o various_a respect_n to_o the_o sun_n and_o that_o the_o equality_n of_o the_o circular_a motion_n be_v measure_v not_o from_o the_o centre_n of_o its_o proper_a circle_n as_o it_o ought_v but_o from_o the_o centre_n of_o another_o eccentric_a circle_n against_o the_o first_o principle_n of_o nature_n and_o art_n invent_v a_o new_a system_fw-la exempt_a from_o all_o these_o incommodity_n which_o be_v in_o truth_n the_o copernican_n invert_v so_o i_o conceive_v that_o in_o the_o borellian_a hypothesis_n and_o explosion_n of_o i_o know_v not_o what_o saline_n and_o acid_n material_n in_o the_o heart_n be_v not_o only_o in_o itself_o extreme_o improbable_a and_o incongruous_a to_o the_o wisdom_n of_o nature_n which_o always_o constitute_v certain_a and_o regular_a cause_n to_o produce_v certain_a and_o regular_a effect_n but_o also_o unnecessary_o suppose_v to_o solve_v the_o phaenomenon_n of_o the_o heart_n pulsation_n set_v my_o dull_a brain_n on_o work_n to_o reform_v it_o and_o soon_o invent_v another_o that_o seem_v both_o free_a from_o those_o inconvenience_n and_o more_o agreeable_a to_o the_o organical_a structure_n of_o the_o heart_n to_o which_o above_o all_o thing_n it_o be_v requisite_a i_o shall_v endeavour_v to_o adjust_a it_o this_o i_o think_v myself_o oblige_v to_o signify_v lest_o any_o here_o shall_v believe_v either_o that_o i_o have_v usurp_v to_o myself_o this_o whole_a system_n of_o the_o motion_n of_o the_o heart_n from_o that_o most_o excellent_a mathematician_n alphonsus_n borellus_n who_o memory_n i_o high_o honour_n or_o that_o i_o lay_v claim_n to_o more_o than_o a_o candid_a attempt_n to_o reform_v it_o ¶_o ⸫_o epilogus_fw-la praelectionum_fw-la quidem_fw-la vela_fw-la jam_fw-la tandem_fw-la contraxi_fw-la nondum_fw-la tamen_fw-la dissolutam_fw-la video_fw-la concionem_fw-la resistamus_fw-la igitur_fw-la hîc_fw-la parumper_fw-la auditores_fw-la ornatissimâ—_n si_fw-la vobis_fw-la ita_fw-la videatur_fw-la &_o ad_fw-la stupendam_fw-la illam_fw-la cujus_fw-la rationem_fw-la mechanicam_fw-la hactenus_fw-la tam_fw-la anxiè_fw-la inquisivimus_fw-la cordis_n fabricam_fw-la seriò_fw-la respiciamus_fw-la ind_n enim_fw-la etiamsi_fw-la alia_fw-la omne_fw-la in_o universitate_fw-la rerum_fw-la deessent_fw-la divinae_fw-la architecturae_fw-la documenta_fw-la cuivis_fw-la hominum_fw-la pronum_fw-la est_fw-la infer_v &_o quam_fw-la sit_fw-la immensa_fw-la illius_fw-la caeterorumque_fw-la omnium_fw-la in_o hoc_fw-la mundo_fw-la adspect_n abilium_fw-la conditoris_fw-la solertia_fw-la quámque_fw-la parum_fw-la ab_fw-la immedicabili_fw-la cum_fw-la animi_fw-la tum_fw-la mentis_fw-la stupiditate_fw-la olim_fw-la abfuerit_fw-la epicurus_n qui_fw-la animalia_fw-la casu_fw-la quodam_fw-la in_fw-la prima_fw-la rerum_fw-la procreatione_fw-la genita_fw-la fuisse_fw-la vecorditer_fw-la censuit_fw-la &_o opinatus_fw-la est_fw-la consequenter_fw-la totam_fw-la in_o iis_fw-la membrorum_fw-la varietatem_fw-la dearticulationemque_fw-la non_fw-la aliunde_fw-la quam_fw-la ex_fw-la atomorum_fw-la fortè_fw-la fortuna_fw-la post_fw-la infinitos_fw-la inter_fw-la se_fw-la in_o spatio_fw-la infinito_fw-la vortices_fw-la ita_fw-la concurrentium_fw-la atque_fw-la commistarum_fw-la dispositione_n extitisse_fw-la quamobrem_fw-la neque_fw-la ullam_fw-la fuisse_fw-la intelligentis_fw-la naturae_fw-la prudentiam_fw-la quae_fw-la ossa_fw-la cerebrum_fw-la cor_fw-la nervos_fw-la venas_fw-la quae_fw-la oculos_fw-la manus_fw-la pedes_fw-la viscera_fw-la quae_fw-la cetera_fw-la omne_fw-la conformans_fw-la ad_fw-la fine_n certos_fw-la seu_fw-la functiones_fw-la partibus_fw-la congruas_fw-la respexerit_fw-la sed_fw-la singulas_fw-la part_n ita_fw