gentian_a wine_n two_o dram_fw-la of_o the_o chalybeate_a wine_n describe_v in_o the_o london_n dispensatory_a increase_v about_o a_o scruple_n every_o day_n till_o you_o come_v to_o half_a a_o ounce_n which_o take_v for_o two_o month_n at_o least_o afterward_o decrease_v as_o you_o increase_v till_o you_o come_v to_o one_o drachm_n and_o so_o give_v over_o but_o if_o you_o find_v oâ—osion_n you_o may_v continue_v that_o course_n long_o or_o as_o long_o as_o your_o physician_n think_v fit_a after_o all_o you_o may_v use_v a_o glass_n of_o claret_n when_o faint_a but_o be_v sure_a to_o be_v moderate_a and_o not_o run_v from_o one_o excess_n to_o another_o as_o for_o the_o acrimony_n of_o blood_n that_o be_v more_o during_o the_o take_v of_o opium_n and_o will_v soon_o after_o gradual_o wear_v off_o especial_o by_o the_o course_n direct_v if_o not_o camphire_n be_v the_o adequate_a remedy_n of_o which_o with_o equal_a part_n of_o white_a rosin_n and_o q._n s._n of_o mucilage_n of_o gum._n tragac._n you_o may_v make_v pill_n of_o â—_o grain_n weight_n take_v 4_o of_o they_o every_o night_n at_o bedtime_n in_o a_o rear_n yolk_n of_o a_o egg_n as_o long_o as_o it_o be_v necessary_a for_o camphire_n by_o its_o fine_a sulphur_n correct_v the_o volatile_a acrimony_n of_o cantharides_n opium_n etc._n etc._n and_o so_o allay_v titillation_n to_o venery_n etc._n etc._n as_o be_v observe_v iv_o the_o ill_a effect_n of_o a_o sudden_a leave_v off_o of_o opium_n as_o anxiety_n distress_n depression_n of_o spirit_n which_o as_o be_v say_v be_v very_o dangerous_a be_v remedy_v no_o other_o way_n but_o either_o 1._o by_o return_v to_o the_o use_v of_o opium_n which_o be_v a_o most_o certain_a cure_n and_o afterward_o if_o you_o please_v give_v over_o the_o use_n of_o it_o after_o the_o manner_n that_o i_o direct_v which_o you_o will_v find_v to_o be_v safe_a nor_o can_v i_o advise_v you_o to_o trust_v any_o other_o method_n of_o leave_v it_o off_o unless_o it_o be_v 2._o by_o substitute_v wine_n instead_o of_o opium_n which_o be_v not_o quite_o so_o safe_a or_o certain_a your_o best_a method_n of_o use_v it_o be_v to_o drink_v a_o good_a glass_n of_o it_o so_o often_o as_o to_o keep_v the_o comfort_n thereof_o at_o stomach_n continual_o that_o so_o it_o may_v answer_v the_o more_o permanent_a effect_n of_o opium_n and_o keep_v you_o from_o a_o faint_a condition_n but_o see_v also_o that_o this_o course_n be_v not_o convenient_a to_o be_v continue_v long_o you_o must_v gradual_o lessen_v the_o do_v of_o this_o as_o you_o be_v direct_v to_o do_v that_o of_o opium_n till_o you_o come_v to_o take_v none_o or_o at_o least_o a_o moderate_a and_o wholesome_a quantity_n note_v that_o if_o such_o as_o use_v to_o take_v opium_n be_v even_o almost_o expire_a for_o want_n of_o it_o you_o must_v to_o prevent_v imminent_a death_n give_v a_o liquid_a preparation_n thereof_o to_o the_o value_n of_o what_o the_o person_n be_v use_v to_o take_v in_o a_o cordial_a vehicle_n as_o spirit_n of_o wine_n brandy_n or_o the_o like_a because_o such_o hot_a spirituous_a vehicles_n do_v as_o have_v be_v show_v immediate_o give_v some_o comfort_n by_o actuate_a and_o warm_v our_o spirit_n till_o the_o opium_n come_v to_o operate_v which_o will_v not_o be_v long_o because_o it_o be_v in_o a_o liquid_a form_n if_o you_o find_v the_o person_n sink_v notwithstanding_o he_o may_v be_v keep_v up_o by_o repeat_v the_o brandy_n or_o cordial_n without_o any_o opium_n in_o it_o till_o the_o opiate_n operate_v which_o will_v certain_o by_o god_n help_n set_v he_o right_n in_o case_n it_o do_v but_o begin_v to_o operate_v before_o he_o be_v dead_a see_v the_o philos._n transact_v for_o june_n july_n august_n 1696._o note_v that_o it_o be_v a_o very_a false_a imagination_n that_o author_n have_v of_o the_o turk_n capacity_n by_o nature_n climate_n or_o the_o like_a to_o take_v more_o opium_n or_o in_o great_a quantity_n than_o we_o may_v but_o that_o they_o make_v more_o use_n of_o it_o and_o by_o that_o mean_n come_v to_o take_v 2_o or_o 3_o dram_fw-la a_o day_n for_o they_o begin_v with_o such_o small_a quantity_n as_o we_o common_o give_v till_o by_o a_o long_a custom_n of_o take_v it_o they_o come_v to_o take_v the_o say_a quantity_n which_o be_v but_o small_a in_o comparison_n of_o what_o several_a english_a people_n that_o have_v be_v use_v to_o it_o do_v or_o have_v take_v as_o i_o can_v name_v several_a to_o you_o if_o i_o have_v not_o reason_n to_o the_o contrary_a however_o i_o be_o at_o liberty_n to_o tell_v you_o the_o quantity_n though_o i_o must_v forbear_v name_v the_o person_n some_o have_v daily_o take_v 2_o 3_o 4_o 5_o 6_o dram_fw-la nay_o i_o have_v hear_v of_o some_o that_o have_v take_v a_o ounce_n a_o day_n and_o of_o one_o that_o take_v two_o ounce_n whereas_o the_o learned_a and_o curious_a dr._n edward_n smith_n can_v find_v none_o about_o smyrna_n who_o take_v above_o 3_o dram_fw-la a_o day_n all_o this_o be_v most_o agreeable_a to_o reason_n and_o the_o whole_a current_n of_o my_o discourse_n viz._n that_o it_o can_v be_v better_o bear_v in_o cold_a than_o hot_a wether_n and_o consequent_o in_o cold_a than_o hot_a climate_n by_o firm_a flesh_v person_n than_o such_o as_o have_v soft_a and_o flaccid_a flesh_n as_o the_o southern_a people_n have_v in_o comparison_n of_o the_o northern_a and_o such_o as_o inhabit_v cold_a country_n therefore_o you_o may_v be_v sure_a that_o such_o as_o inquire_v into_o the_o cause_n why_o the_o turk_n and_o other_o eastern_a people_n can_v take_v great_a quantity_n than_o we_o can_v seek_v for_o the_o reason_n of_o thing_n before_o they_o know_v the_o fact_n nay_o when_o the_o fact_n be_v quite_o contrary_a to_o what_o they_o build_v upon_o we_o may_v as_o well_o expect_v edify_v discourse_n from_o they_o that_o inquire_v why_o fire_n be_v cold_a water_n dry_a and_o the_o like_a as_o from_o such_o as_o suppose_v thing_n contrary_a to_o true_a and_o sensible_a experience_n chap._n xxix_o some_o general_a rule_n caution_n &c_n &c_n concern_v the_o use_n of_o opium_n though_o there_o be_v hardly_o any_o rule_n caution_n or_o thing_n worthy_a of_o observation_n concern_v the_o use_n of_o opium_n but_o what_o be_v imply_v or_o easy_o inferable_a from_o what_o have_v be_v say_v nor_o now_o that_o the_o true_a nature_n of_o opium_n be_v discover_v can_v there_o be_v such_o fear_n and_o jealoufy_v which_o multiply_v caution_n concern_v the_o administration_n thereof_o for_o every_o one_o may_v now_o easy_o see_v wherein_o its_o danger_n and_o benefit_n lie_v yet_o because_o a_o chapter_n of_o rule_n and_o caution_n may_v be_v expect_v as_o be_v usual_a and_o to_o have_v a_o single_a view_n of_o such_o as_o lie_v more_o scatter_v and_o not_o so_o ready_o find_v in_o the_o body_n of_o the_o book_n i_o will_v to_o introduce_v the_o use_n of_o opium_n with_o more_o clearness_n and_o perfect_a security_n give_v you_o a_o collection_n of_o general_a rule_n and_o caution_n concern_v its_o use_n whereof_o some_o be_v mention_v and_o most_o inferable_a from_o the_o premise_n i._o as_o to_o its_o substance_n 1._o it_o shall_v be_v always_o give_v free_v from_o its_o resinous_n part_n if_o you_o can_v get_v such_o a_o preparation_n 2._o it_o be_v also_o neat_a and_o convenient_a that_o it_o shall_v be_v free_v from_o all_o its_o earth_n and_o dress_n 3._o never_o give_v opium_n but_o either_o so_o prepare_v or_o with_o its_o rosin_n so_o subdue_v segregated_a or_o alter_v as_o i_o have_v show_v in_o the_o safe_a preparation_n thereof_o iâ—_n follow_v that_o 4._o crude_a opium_n and_o extract_v make_v in_o sulphureous_a spirit_n be_v utter_o to_o be_v reject_v 5._o never_o give_v it_o mix_v or_o join_v with_o resinous_a thing_n as_o have_v be_v intimate_v 6._o never_o mix_v or_o join_v it_o with_o other_o opiate_n 1._o because_o none_o of_o they_o be_v so_o good_a 2._o because_o they_o be_v not_o so_o well_o know_v 3._o because_o it_o make_v the_o do_v more_o uncertain_a 4._o because_o those_o other_o opiate_n be_v use_v unprepared_a 7._o pil._n e_o styrace_n because_o make_v of_o resinous_a opium_n join_v with_o resinous_a thing_n as_o styrax_fw-la calam_fw-la and_o olibanum_n be_v a_o insufferable_a preparation_n though_o commend_v and_o therefore_o have_v frequent_a ill_a effect_n to_o my_o knowledge_n 8._o pil._n â—_o cynoglossâ_fw-la be_v such_o another_o have_v two_o opiate_n in_o it_o beside_o opium_n extract_v out_o of_o spirit_n of_o wine_n which_o be_v far_o worse_a than_o crude_a opium_n though_o by_o the_o way_n of_o eminence_n call_v opium_n prepare_v in_o our_o dispensatory_a styrax_n calam_fw-la and_o olibanum_n which_o be_v resinous_a 9_o laudan_n lond._n be_v also_o a_o ill_a preparation_n as_o have_v the_o
a_o very_o long_o and_o lavish_a use_n thereof_o the_o inconvenience_n of_o leave_v off_o the_o use_n of_o opium_n do_v bear_v a_o certain_a proportion_n to_o the_o time_n and_o quantity_n that_o it_o have_v be_v use_v in_o 1._o note_v that_o the_o turk_n do_v drink_v some_o water_n always_o after_o the_o take_n of_o opium_n as_o be_v the_o best_a menstruum_fw-la to_o dissolve_v it_o 2._o note_v that_o it_o be_v usual_a with_o they_o to_o take_v a_o drachm_n in_o the_o morning_n and_o so_o much_o in_o the_o afternoon_n and_o so_o may_v we_o as_o well_o as_o they_o if_o use_v to_o it_o and_o it_o be_v a_o very_a silly_a say_n that_o you_o will_v find_v in_o author_n that_o they_o be_v better_a able_a to_o bear_v it_o because_o of_o the_o climate_n etc._n etc._n whereas_o the_o more_o northern_a person_n be_v better_a able_a to_o take_v it_o than_o the_o southern_a as_o will_v hereafter_o appear_v most_o plain_o i_o be_o tell_v of_o one_o near_o banbury_n that_o take_v two_o ounce_n a_o day_n 3._o note_v that_o among_o the_o effect_n of_o opium_n may_v be_v observe_v many_o seem_a contradiction_n yet_o be_v there_o nothing_o more_o certain_a than_o the_o several_a different_a matter_n of_o fact_n which_o no_o doubt_n have_v be_v a_o great_a cause_n to_o puzzle_v the_o world_n about_o it_o and_o to_o run_v man_n into_o strange_a absurdity_n concern_v its_o operation_n and_o all_o to_o deviate_v so_o far_o from_o the_o truth_n that_o nothing_o in_o nature_n can_v be_v far_o unless_o you_o will_v say_v that_o heat_n cool_v or_o what_o please_v the_o sensitive_a soul_n be_v at_o the_o same_o time_n abhor_v by_o it_o now_o because_o these_o seem_a contradiction_n in_o the_o effect_n of_o opium_n be_v the_o great_a rub_n to_o be_v meet_v with_o and_o that_o the_o reader_n may_v take_v the_o better_a estimate_n of_o the_o undertake_n and_o my_o explication_n of_o its_o effect_n when_o i_o come_v to_o it_o i_o shall_v not_o fear_v to_o enumerate_v they_o distinct_o though_o they_o will_v make_v the_o strange_a catalogue_n of_o riddle_n that_o ever_o be_v see_v trust_v in_o he_o that_o create_v this_o wonderful_a medicament_n that_o he_o will_v enable_v i_o to_o explain_v all_o its_o effect_n the_o seem_a contradiction_n in_o the_o effect_n of_o opium_n 1._o it_o cause_v sleep_v and_o watch_v 2._o it_o cause_n and_o prevent_v sweat_n 3._o it_o relax_n and_o stop_v looseness_n 4._o it_o stop_v flux_n and_o cause_n that_o of_o sweat_n etc._n etc._n 5._o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v by_o that_o sense_n to_o venery_n 6._o it_o cause_v stupidity_n and_o promptitude_n in_o business_n cloudiness_n and_o serenity_n of_o mind_n 7._o it_o excite_v the_o spirit_n and_o quiet_v they_o 8._o it_o be_v very_o hot_a yet_o cool_v in_o fever_n 9_o it_o be_v hot_a and_o bitter_a yet_o lessen_v appetite_n even_o in_o cold_a stomach_n 10._o it_o stop_v and_o promote_v urine_n 11._o it_o relax_n and_o weaken_v yet_o enable_v we_o to_o undergo_v labour_n journey_n etc._n etc._n 12._o it_o cause_n and_o prevent_v abortion_n 13._o it_o stop_v vomit_v above_o all_o thing_n yet_o cause_n most_o violent_a tedious_a and_o dangerous_a vomit_n 14._o it_o stop_v purge_v in_o a_o most_o eminent_a manner_n yet_o sometime_o cause_v it_o 15._o it_o be_v very_o acrimonious_a yet_o as_o all_o say_v obtund_v acrimony_n however_o it_o allay_v pain_n proceed_v from_o acrimony_n 16._o it_o cause_v a_o furious_a madness_n yet_o compose_v the_o spirit_n above_o all_o thing_n 17._o it_o cause_v 〈◊〉_d yet_o sometime_o cure_v they_o as_o willis_n say_v 18._o it_o cause_v palsy_n yet_o have_v i_o know_v it_o to_o cure_v a_o palsy_n 19_o it_o cause_v dryness_n in_o the_o mouth_n yet_o take_v off_o thirst_n in_o fever_n 20._o it_o cure_v and_o cause_v a_o hiccough_n 21._o it_o stanche_n blood_n yet_o cause_v the_o blood_n to_o come_v outward_a as_o appear_v by_o the_o efflorescence_n or_o redness_n of_o the_o skin_n that_o it_o cause_n yet_o move_v the_o menses_fw-la and_o lochia_n 22._o we_o have_v many_o instance_n of_o it_o promote_a and_o hinder_v critical_a motion_n 23._o it_o raise_v very_o weak_a people_n when_o nothing_o beside_o will_v do_v it_o yet_o it_o kill_v other_o weak_a people_n 24._o it_o cause_n and_o cure_n convulsion_n 25._o it_o cause_v relaxation_n and_o contraction_n of_o the_o same_o part_n 26._o it_o relax_n yet_o cause_v rigidity_n tension_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n thus_o have_v i_o fair_o and_o faithful_o lay_v the_o whole_a onus_fw-la of_o the_o operation_n effect_n and_o contradictory_n phenomena_n of_o opium_n upon_o my_o shoulder_n however_o i_o come_v off_o and_o clear_v myself_o of_o the_o intricacy_n maze_n and_o cross_a effect_n thereof_o by_o explain_v they_o which_o none_o upon_o the_o view_n thereof_o will_v think_v possible_a and_o none_o before_o i_o dare_v as_o much_o as_o enumerate_v for_o that_o end_n chap._n vii_o the_o author_n contrive_v a_o compendious_a way_n of_o examine_v all_o opinion_n concern_v the_o operation_n of_o opium_n have_v without_o any_o sly_a or_o sordid_a evasion_n or_o considerable_a omission_n which_o have_v be_v the_o perfidious_a course_n of_o author_n in_o this_o case_n full_o and_o true_o enumerate_v the_o sensible_a and_o certain_a effect_n of_o opium_n in_o humane_a body_n and_o thereby_o empanneled_a a_o just_a jury_n for_o the_o trial_n of_o hypothesise_n which_o must_v be_v judge_v by_o the_o effect_n or_o phenomena_n of_o opium_n i_o will_v now_o proceed_v to_o their_o examination_n but_o because_o it_o will_v be_v endless_a to_o take_v every_o one_o particular_o into_o consideration_n i_o will_v use_v their_o stratagem_n who_o blow_v up_o foundation_n to_o save_v the_o tedious_a peck_v at_o all_o the_o part_n of_o the_o superstructure_n which_o in_o this_o case_n will_v require_v a_o age_n and_o take_v up_o all_o my_o time_n in_o demolish_n they_o which_o may_v be_v better_o employ_v in_o erect_v something_o that_o may_v be_v useful_a i_o have_v consider_v and_o find_v that_o the_o foundation_n in_o which_o all_o author_n both_o ancient_a and_o modern_a agree_v and_o whereupon_o they_o have_v hitherto_o endeavour_v to_o build_v look_v upon_o it_o as_o firm_a and_o warrantable_a in_o all_o age_n be_v this_o viz._n that_o opium_n operate_v by_o diminish_v or_o disable_n the_o spirit_n mean_v the_o animal_n spirit_n the_o ancient_n affirm_v that_o it_o do_v so_o by_o a_o extreme_a cold_a quality_n etc._n etc._n and_o the_o modern_n who_o observe_v it_o to_o act_n while_o it_o be_v at_o stomach_n by_o affect_v the_o brain_n nerve_n animal_n spirit_n etc._n etc._n and_o conclude_v no_o action_n be_v perform_v without_o contact_n infer_v and_o agree_v because_o no_o visible_a passage_n can_v be_v find_v from_o the_o stomach_n to_o the_o head_n that_o it_o must_v of_o absolute_a necessity_n act_v by_o fume_n vapour_n auras_fw-la or_o effluvium_n send_v up_o out_o of_o the_o stomach_n to_o the_o brain_n nerve_n etc._n etc._n so_o that_o all_o the_o remain_a question_n among_o the_o modern_n be_v which_o way_n those_o fume_n or_o vapour_n do_v the_o feat_n all_o allow_v the_o fume_n do_v it_o one_o say_v that_o they_o stuff_v the_o pore_n of_o the_o brain_n and_o so_o hinder_v the_o generation_n of_o animal_n spirit_n a_o second_o that_o they_o constringed_a and_o close_v the_o pore_n together_o thereby_o hinder_v the_o say_a generation_n a_o three_o that_o they_o fix_v and_o coagulate_v the_o animal_n spirit_n as_o wedelius_n and_o other_o a_o four_o that_o they_o cloud_v the_o animal_n spirit_n a_o five_o that_o they_o act_v as_o a_o poison_n as_o willis_n and_o many_o other_o a_o six_o that_o they_o clog_v the_o animal_n spirit_n by_o adhere_v to_o they_o etc._n etc._n not_o know_v nor_o i_o think_v care_v what_o they_o say_v so_o they_o humour_a their_o own_o imagination_n and_o hypothesise_n though_o utter_o incapable_a of_o solve_v the_o effect_n of_o opium_n especial_o be_v most_o constant_a proper_a and_o genuine_a effect_n for_o how_o can_v a_o cold_a quality_n which_o opium_n never_o have_v cause_v a_o gay_a and_o brisk_a humour_n bravery_n magnanimity_n euphory_n in_o labour_n promptitude_n to_o venus_n etc._n etc._n and_o how_o can_v cloud_n of_o vapour_n hinder_v the_o generation_n of_o animal_n spirit_n by_o stuff_v or_o constr_v the_o pore_n of_o the_o brain_n poison_v fix_v coagulate_v clog_a or_o cloud_v the_o animal_n spirit_n cause_v a_o fine_a ovation_n thereof_o a_o gay_a brave_a courageous_a and_o magnanimous_a disposition_n euphory_n promptitude_n to_o venery_n serenity_n expediteness_n in_o management_n etc._n etc._n which_o be_v as_o have_v be_v say_v the_o constant_a and_o proper_a effect_n of_o opium_n nor_o indeed_o be_v any_o of_o those_o author_n so_o foolhardy_a as_o to_o attempt_v it_o
etc._n as_o wine_n hot_a liquor_n and_o opium_n do_v 12._o opium_n do_v very_o much_o open_v the_o pore_n and_o cause_n perspiration_n etc._n etc._n which_o only_a heat_n as_o that_o in_o bath_n bagnio_n hot_a house_n and_o hot_a thing_n do_v but_o cold_a shut_v the_o pore_n as_o all_o know_v therefore_o 13._o opium_n cure_v and_o prevent_v cold_n which_o be_v another_o argument_n of_o its_o heat_n 14._o it_o be_v a_o great_a aphrodisiack_a or_o exciter_n to_o venery_n which_o cold_a thing_n chill_a but_o hot_a thing_n as_o cantharides_n bee_n pismire_n onion_n garlic_n leek_n rocket_n squill_n horse_n radish_n sem._n human._n etc._n etc._n do_v promote_v 15._o nothing_o cause_v indolence_n give_v internal_o but_o wine_n hot_a liquor_n etc._n etc._n as_o i_o can_v think_v of_o and_o opium_n cause_v it_o much_o after_o the_o same_o manner_n as_o wine_n do_v first_o cause_v mirth_n and_o jollity_n and_o upon_o increase_n of_o quantity_n very_o considerable_a indolence_n it_o be_v true_a that_o cold_a will_v external_o cause_v a_o stupor_n if_o it_o be_v intense_a so_o as_o to_o constringe_v the_o part_n and_o exclude_v the_o spirit_n but_o otherwise_o it_o make_v the_o feel_v more_o nice_a as_o all_o know_v by_o experience_n because_o every_o little_a hurt_n affect_v we_o more_o when_o we_o be_v cold_a than_o hot_a but_o this_o be_v not_o the_o case_n of_o relax_a opium_n which_o be_v use_v internal_o to_o take_v away_o pain_n as_o wine_n etc._n etc._n 16._o nothing_o take_v away_o the_o effect_n of_o opium_n or_o drunkeness_n better_o than_o cold_a thing_n internal_o and_o external_o as_o acid_n dip_v in_o cold_a water_n etc._n etc._n 17._o opium_n relax_n all_o part_n which_o heat_n do_v and_o cold_a constringe_n as_o be_v intimate_v 18._o wedelius_n confess_v though_o it_o make_v against_o what_o he_o say_v that_o he_o never_o observe_v a_o soporose_n distemper_n where_o there_o be_v not_o a_o preternatural_a heat_n opiolog_fw-la lib._n 1._o sect._n 1_o cap._n 12._o p._n 46._o 19_o if_o it_o cause_v sleep_n by_o its_o cold_a quality_n than_o all_o thing_n that_o be_v cold_a will_v do_v it_o proportionable_o cucumber_n purslane_n etc._n etc._n will_v be_v so_o great_a hypnotick_n that_o we_o shall_v not_o be_v able_a to_o eat_v a_o drachm_n of_o they_o but_o that_o they_o will_v cause_v a_o great_a sopor_fw-la but_o there_o be_v no_o such_o thing_n and_o hot_a thing_n be_v much_o more_o apt_a to_o cause_v sleep_n or_o a_o sopor_fw-la as_o wine_n hot_a spirit_n onion_n garlic_n and_o such_o like_a 20._o opium_n cause_v a_o redness_n or_o efflorescence_n of_o the_o skin_n make_v it_o sensible_o warm_a as_o heat_n wine_n and_o strong_a liquor_n do_v 21._o it_o cause_v also_o a_o itch_a of_o the_o skin_n which_o only_o hot_a thing_n do_v 22._o half_n a_o drachm_n of_o opium_n in_o clyster_n have_v cause_v a_o violent_a heat_n in_o the_o gut_n 23._o it_o stop_v diarrheas_n or_o looseness_n which_o cold_a cause_n 24._o it_o stop_v defluxion_n cough_n etc._n etc._n which_o cold_a cause_n 25._o to_o pin_v up_o all_o its_o predominant_a principle_n appear_v by_o autopsie_n upon_o its_o chemical_a analysis_n to_o be_v volatile_a salt_n and_o sulphur_n beside_o this_o opinion_n of_o the_o coldness_n of_o opium_n be_v very_o much_o explode_v and_o indeed_o it_o be_v so_o apparent_o false_a and_o absurd_a that_o i_o shall_v not_o have_v think_v it_o worth_a while_n to_o argue_v against_o it_o but_o that_o it_o lay_v so_o in_o my_o way_n that_o regular_o i_o can_v not_o well_o avoid_v it_o without_o breach_n of_o order_n and_o method_n i_o may_v have_v add_v that_o it_o resolve_v attenuate_v etc._n etc._n but_o it_o be_v needless_a to_o say_v any_o more_o it_o be_v very_o false_a and_o erroneous_a that_o it_o stop_v flux_n by_o incrassate_v and_o bind_v which_o be_v account_v cold_a quality_n if_o so_o how_o shall_v it_o stop_v they_o when_o pound_n of_o incrassative_n and_o binder_n have_v fail_v though_o the_o opium_n be_v give_v only_o in_o the_o quantity_n of_o a_o grain_n or_o two_o how_o shall_v it_o stop_v or_o moderate_a flux_n even_o while_o it_o be_v yet_o at_o stomach_n as_o it_o most_o certain_o do_v it_o bear_v as_o etmuller_n well_o observe_v no_o proportion_n to_o the_o blood_n and_o humour_n to_o have_v any_o effect_n that_o may_v be_v remarkable_a upon_o they_o for_o a_o grain_n be_v but_o as_o 1_o to_o 115200_o to_o the_o blood_n of_o he_o that_o have_v 20_o pound_n of_o blood_n which_o a_o ordinary_a man_n have_v beside_o how_o can_v altenuative_n resolver_n and_o discusser_n incrassate_fw-it or_o bind_z but_o more_o especial_o how_o can_v so_o great_a a_o relaxer_n of_o part_n be_v a_o constringer_n thereof_o that_o be_v perfect_a contradiction_n and_o how_o can_v a_o mere_a sal_fw-la volatile_a oleosum_fw-la in_o which_o all_o its_o virtue_n lie_v as_o will_v plain_o appear_v thicken_v and_o bind_v the_o truth_n be_v that_o it_o stop_v flux_n as_o sleep_n do_v by_o take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o solicit_v the_o part_n to_o contract_n and_o so_o to_o extrude_v and_o squeeze_v they_o out_o it_o promote_v perspiration_n by_o relax_v the_o pore_n as_o sleep_n do_v it_o also_o seem_v to_o thicken_v rheum_n as_o sleep_n do_v because_o it_o cause_v sleep_n or_o at_o least_o take_v away_o a_o sense_n of_o the_o irritation_n of_o the_o rheum_n be_v thereby_o suffer_v to_o stay_v till_o it_o thicken_v by_o the_o heat_n of_o the_o body_n the_o irritation_n also_o at_o windpipe_n be_v less_o because_o the_o flux_n of_o the_o rheum_n be_v moderate_v for_o the_o reason_n aforesaid_a but_o of_o these_o thing_n more_o full_o when_o we_o come_v to_o explain_v the_o cause_n or_o cause_n of_o the_o effect_n of_o opium_n chap._n x._o it_o be_v prove_v that_o opium_n send_v no_o fume_n etc._n etc._n from_o the_o stomach_n to_o the_o head_n brain_n etc._n etc._n and_o therefore_o that_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n etc._n etc._n by_o that_o mean_n though_o the_o opinion_n of_o the_o cold_a of_o opium_n be_v much_o explode_v that_o of_o fume_n vapour_n or_o aura_n arise_v from_o the_o opium_n at_o stomach_n and_o mount_v up_o to_o the_o brain_n etc._n etc._n be_v as_o much_o receive_v and_o embrace_v i_o know_v none_o but_o such_o as_o think_v it_o absolute_o necessary_a consider_v that_o it_o be_v most_o certain_a and_o allow_v by_o all_o observe_a man_n that_o opium_n produce_v all_o or_o most_o of_o its_o effect_n while_o it_o be_v at_o stomach_n that_o the_o genus_fw-la neruâ—sum_fw-la be_v most_o concern_v in_o its_o operation_n and_o that_o as_o be_v say_v there_o be_v no_o operation_n or_o action_n but_o by_o contact_n so_o that_o the_o modern_n acquiesce_v in_o the_o necessity_n of_o its_o operate_n that_o way_n because_o they_o can_v conceive_v no_o other_o which_o be_v no_o proof_n but_o a_o defect_n of_o their_o conception_n look_v upon_o it_o as_o invincible_a and_o uncontrollable_a evidence_n oâ—_n its_o operate_n by_o detachment_n of_o fume_n or_o 〈◊〉_d send_v up_o to_o the_o brain_n from_o the_o stomach_n which_o appear_v so_o undeniable_o conclusive_a that_o neither_o the_o want_n of_o a_o sensible_a passage_n nor_o any_o other_o inconvenience_n signify_v any_o thing_n with_o they_o to_o the_o contrary_a therefore_o it_o become_v a_o establish_a foundation_n by_o common_a consent_n only_o they_o differ_v as_o be_v show_v in_o the_o manner_n how_o those_o fume_n produce_v the_o effect_n of_o opium_n and_o well_o they_o may_v see_v there_o be_v no_o such_o thing_n nor_o possibility_n if_o they_o be_v of_o ever_o explicate_v the_o various_a effect_n of_o opium_n by_o that_o mean_n as_o will_v manifest_o appear_v i_o confess_v that_o if_o opium_n operate_v by_o such_o fume_n pass_v from_o the_o stomach_n to_o the_o brain_n etc._n etc._n it_o will_v be_v easy_a to_o conceive_v how_o it_o shall_v diminish_v or_o disable_v nay_o utter_o ruin_v the_o animal_n spirit_n and_o indeed_o impossible_a rational_o to_o conceive_v how_o they_o can_v do_v otherwise_o but_o then_o the_o enliven_a invigorate_n and_o encourage_v effect_n of_o opium_n which_o be_v its_o constant_a and_o most_o genuine_a off_o spring_n will_v lie_v upon_o our_o hand_n without_o any_o possibility_n of_o give_v a_o account_n thereof_o for_o certain_o dull_a heavy_a unnatural_a undigested_a and_o cloudy_a fume_n or_o vapour_n can_v not_o advantage_v the_o animal_n spirit_n cause_v a_o triumph_n or_o ovation_n thereof_o at_o their_o access_n courage_n serenity_n promptitude_n magnanimity_n euphory_n inclination_n to_o venery_n etc._n etc._n which_o we_o be_v most_o oblige_v to_o regard_n as_o be_v its_o most_o natural_a and_o proper_a effect_n this_o opinion_n of_o the_o modern_n do_v presume_v or_o suppose_v for_o they_o prove_v nothing_o first_o that_o fume_n
best_a part_n of_o opium_n which_o be_v so_o much_o the_o better_a the_o more_o it_o abound_v with_o they_o 9_o if_o it_o yield_v any_o other_o tincture_n than_o red_a it_o be_v not_o right_a and_o the_o dull_a or_o pale_a the_o red_a be_v the_o worse_a or_o weak_a it_o be_v 10._o the_o best_a be_v heavy_a in_o proportion_n to_o its_o bulk_n which_o you_o may_v soon_o experiment_n thus_o weigh_v a_o ounce_n of_o each_o in_o the_o air_n then_o weigh_v they_o just_a as_o they_o be_v in_o the_o brass_n scales_n in_o water_n and_o the_o heavy_a will_n outweigh_v the_o other_o in_o water_n for_o the_o heavy_a any_o thing_n be_v the_o less_o water_n take_v from_o its_o weight_n in_o proportion_n to_o its_o bulk_n this_o be_v a_o infallible_a and_o most_o ready_a way_n to_o know_v the_o weight_n of_o any_o thing_n in_o proportion_n to_o its_o bulk_n note_v that_o my_o discourse_n be_v most_o particular_o concern_v the_o best_a sort_n of_o crude_a turkey_n opium_n that_o be_v the_o best_a that_o we_o have_v in_o common_a use_n and_o that_o its_o effect_n and_o not_o those_o of_o any_o preparation_n thereof_o be_v set_v down_o in_o the_o follow_a chapter_n chap_n iii_o the_o effect_n of_o opium_n use_v external_o opium_n use_v external_o have_v two_o sort_n of_o effect_n upon_o a_o humane_a body_n 1._o as_o a_o opiate_n to_o cause_n sleep_n take_v away_o pain_n etc._n etc._n 2._o as_o a_o alterative_a of_o the_o part_n it_o be_v apply_v to_o i._o as_o a_o opiate_n it_o be_v of_o very_o uncertain_a and_o uneven_a effect_n when_o apply_v external_o for_o sometime_o it_o cause_v sleep_n take_v away_o pain_n but_o it_o often_o fail_v therefore_o it_o be_v general_o much_o better_a safe_a more_o certain_a and_o effectual_a to_o use_v it_o internal_o i_o do_v scarce_o know_v the_o case_n wherein_o it_o be_v better_a to_o use_v it_o external_o than_o internal_o unless_o it_o be_v to_o smell_v to_o in_o some_o case_n but_o of_o these_o thing_n more_o particular_o when_o we_o come_v to_o the_o use_v of_o opium_n in_o cure_v prevent_v or_o paliate_a disease_n for_o here_o we_o only_o lie_v down_o effect_n in_o order_n to_o a_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n to_o which_o its_o internal_a effect_n will_v main_o contribute_v however_o it_o may_v be_v very_o useful_a to_o that_o end_n to_o lay_v down_o its_o alterative_a effect_n for_o thereby_o we_o shall_v in_o good_a measure_n know_v the_o prin_fw-mi ciple_n by_o which_o it_o operate_v ii_o it_o be_v external_a effect_n as_o a_o alterative_a be_v these_o viz._n 1._o it_o incides_fw-la resolve_n and_o discuss_n 2._o it_o relax_n and_o mollify_v 3._o it_o maturate_v and_o suppurate_v 4._o it_o exulcerate_v or_o cause_n blister_n if_o it_o be_v very_o strong_a and_o apply_v to_o person_n of_o a_o fine_a texture_n where_o the_o skin_n be_v tender_a but_o this_o effect_n belong_v more_o proper_o to_o the_o maslack_n or_o true_a 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o drop_n from_o the_o incision_n make_v in_o the_o head_n of_o the_o poppy_n especial_o the_o theban_a which_o afford_v a_o very_a powerful_a juice_n hence_o you_o may_v observe_v that_o the_o more_o it_o exulcerates_n or_o blister_n the_o better_a be_v the_o opium_n &_o vice_fw-la versâ_fw-la 5._o it_o be_v a_o psilotherick_n for_o it_o prevent_v hair_n to_o grow_v and_o cause_v the_o shed_v thereof_o 6._o it_o be_v hurtful_a to_o the_o eye_n and_o ear_n 7._o it_o excite_v itch_n apply_v in_o a_o moderate_a manner_n to_o the_o skin_n 8._o it_o excite_v venery_n apply_v to_o the_o perinaeum_n chap._n iu._n the_o effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o the_o moderate_a do_v in_o ordinary_a use_n to_o produce_v the_o follow_a effect_n be_v from_o one_o to_o three_o grain_n more_o or_o less_o according_a to_o the_o circumstance_n condition_n case_n constitution_n age_n &c_n &c_n of_o the_o person_n who_o take_v it_o 2._o it_o operate_v general_o in_o a_o short_a time_n after_o it_o be_v in_o the_o stomach_n that_o be_v in_o about_o half_a a_o hour_n more_o or_o less_o if_o take_v in_o a_o liquid_a form_n and_o in_o about_o a_o hour_n more_o or_o less_o if_o in_o a_o solid_a form_n drink_v a_o draught_n of_o water_n or_o some_o liquor_n after_o it_o otherwise_o it_o may_v be_v sometime_o near_o a_o hour_n and_o a_o half_a before_o it_o have_v its_o full_a effect_n but_o the_o time_n of_o its_o operation_n have_v a_o considerable_a latitude_n according_a to_o the_o disposition_n of_o the_o stomach_n and_o other_o circumstance_n as_o the_o vehicle_n it_o be_v take_v in_o etc._n etc._n the_o constant_a effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o diffuse_v itself_o in_o a_o kind_n of_o indefinite_a manner_n seizing_z one_o not_o unlike_o the_o gentle_a sweet_a deliquium_fw-la that_o we_o find_v upon_o our_o entrance_n into_o a_o most_o agreeable_a slumber_n which_o upon_o yield_v to_o it_o general_o end_v in_o sleep_n but_o if_o the_o person_n keep_v himself_o in_o action_n discourse_n or_o business_n it_o seem_v especial_o when_o give_v in_o a_o mornning_a after_o a_o moderate_a rest_n at_o night_n like_o a_o most_o delicious_a and_o extraordinary_a refreshment_n of_o the_o spirit_n upon_o very_o good_a news_n or_o any_o other_o great_a cause_n of_o joy_n as_o the_o sight_n of_o a_o dear_o belove_a person_n etc._n etc._n thought_n to_o have_v be_v lose_v at_o sea_n or_o the_o like_a cause_v such_o a_o pleasant_a ovation_n of_o the_o spirit_n serenity_n etc._n etc._n as_o we_o find_v after_o a_o competent_a measure_n of_o generous_a wine_n ad_fw-la hilaritatem_fw-la as_o man_n use_v to_o say_v it_o be_v indeed_o so_o unexpressible_o fine_a and_o sweet_a a_o pleasure_n that_o it_o be_v very_o difficult_a for_o i_o to_o describe_v or_o any_o to_o conceive_v it_o but_o such_o as_o actual_o feel_v it_o for_o it_o be_v as_o if_o a_o good_a genius_n possess_v or_o inform_v a_o man_n therefore_o people_n do_v common_o call_v it_o a_o heavenly_a condition_n as_o if_o no_o worldly_a pleasure_n be_v to_o be_v compare_v with_o it_o helmontianus_fw-la will_v doubtless_o express_v it_o by_o the_o archaeus_n in_o his_o very_a best_a humour_n it_o have_v be_v compare_v not_o without_o good_a cause_n to_o a_o permanent_a gentle_a degree_n of_o that_o pleasure_n which_o modesty_n forbid_v the_o name_n of_o and_o it_o be_v well_o worth_a a_o remark_n that_o both_o be_v pleasure_n of_o the_o same_o sense_n viz._n that_o of_o feel_v for_o it_o can_v be_v a_o pleasure_n of_o any_o other_o sense_n since_o it_o be_v internal_a 2._o it_o cause_v a_o brisk_a gay_a and_o good_a humour_n nor_o do_v i_o doubt_v but_o it_o have_v this_o effect_n upon_o sleep_a person_n as_o far_o as_o their_o condition_n be_v capable_a of_o observe_v it_o for_o you_o shall_v have_v they_o often_o tell_v of_o pleasant_a dream_n after_o it_o when_o they_o remember_v they_o and_o speak_v of_o any_o see_v bauchin_n and_o the_o author_n mention_v below_o under_o the_o four_o effect_n of_o opium_n 3._o it_o cause_v promptitude_n serenity_n alacrity_n and_o expediteness_n in_o dispatch_v and_o manage_n of_o business_n to_o which_o end_n and_o that_o of_o a_o good_a and_o gay_a humour_n which_o be_v near_o of_o kind_n it_o be_v common_o take_v in_o the_o morning_n in_o the_o eastern_a country_n with_o most_o certain_a effect_n the_o truth_n of_o which_o wedelius_n be_v force_v to_o confess_v though_o quite_o contrary_a to_o his_o hypothesis_n of_o opium_n fix_v and_o coagulate_v the_o spirit_n give_v a_o instance_n of_o a_o certain_a serene_a person_n who_o when_o she_o have_v any_o affair_n of_o great_a moment_n to_o dispatch_v do_v beforehand_o take_v opium_n with_o great_a advantage_n for_o she_o thereby_o find_v herself_o every_o way_n better_o dispose_v for_o business_n and_o more_o enable_v to_o bear_v the_o fatigue_n thereof_o which_o be_v the_o substance_n of_o what_o he_o write_v in_o latin_n many_o other_o author_n confirm_v the_o truth_n of_o these_o effect_n but_o above_o all_o the_o constant_a experience_n of_o the_o eastern_a nation_n put_v it_o out_o of_o all_o doubt_n 4._o it_o cause_v assurance_n ovation_n of_o the_o spirit_n courage_n contempt_n of_o danger_n and_o magnanimity_n much_o after_o the_o manner_n that_o generous_a wine_n do_v instead_o of_o which_o the_o turk_n etc._n etc._n use_v opium_n before_o engagement_n desperate_a attack_n etc._n etc._n as_o be_v most_o notorious_a to_o make_v they_o courageous_a which_o it_o certain_o do_v for_o your_o satisfaction_n as_o to_o this_o and_o other_o effect_n of_o opium_n not_o so_o common_o observe_v
why_o then_o do_v they_o write_v and_o trouble_v the_o world_n to_o peruse_v their_o book_n when_o they_o be_v so_o far_o from_o explain_v the_o property_n of_o opium_n that_o they_o scarce_o ever_o dare_v mention_v they_o nor_o set_v their_o hypothesise_n and_o they_o as_o much_o as_o in_o view_n of_o one_o another_o be_v not_o this_o a_o tacit_n confession_n of_o the_o incompetency_n of_o their_o supposition_n i_o beg_v pardon_n for_o call_v they_o they_o though_o they_o themselves_o do_v for_o i_o can_v offer_v they_o a_o great_a abuse_n than_o lay_v their_o spurious_a and_o lame_a brat_n at_o their_o door_n though_o one_o scarce_o need_v say_v any_o more_o of_o they_o yet_o lest_o i_o be_v think_v presumptuous_a or_o saucy_a for_o so_o much_o as_o offer_v to_o suspect_v the_o general_a foundation_n of_o all_o the_o famous_a author_n that_o ever_o live_v as_o galen_n avicenna_n etc._n etc._n among_o the_o ancient_n etmuller_n willis_n etc._n etc._n among_o the_o modern_n 1._o i_o will_v show_v you_o very_o just_a cause_n to_o suspect_v the_o insufficiency_n of_o the_o general_a foundation_n viz._n that_o opium_n diminish_v or_o disable_v the_o spirit_n 2._o i_o will_v prove_v that_o it_o do_v not_o do_v it_o by_o a_o cold_a quality_n 3._o that_o it_o do_v not_o do_v it_o by_o vapour_n fume_n aura_n or_o any_o such_o way_n 4._o that_o it_o diminish_v or_o disable_v the_o spirit_n by_o no_o mean_n whatsoever_o which_o diminish_v or_o disable_n of_o the_o spirit_n cold_a quality_n and_o fume_n or_o aura_n comprehend_v the_o foundation_n of_o all_o opinion_n concern_v opium_n that_o ever_o i_o read_v or_o hear_v of_o and_o consequent_o if_o those_o two_o fundamental_a opinion_n be_v refute_v all_o the_o superstructure_n that_o have_v be_v in_o this_o case_n must_v fall_v to_o the_o ground_n chap._n viii_o the_o author_n show_v just_a cause_n of_o his_o suspicion_n that_o all_o author_n have_v go_v upon_o a_o wrong_a foundation_n in_o their_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n i_o have_v show_v you_o that_o the_o general_a foundation_n of_o both_o ancient_n and_o modern_a author_n be_v that_o opium_n do_v diminish_v or_o disable_v the_o spirit_n and_o now_o i_o will_v plain_o show_v just_a cause_n of_o my_o suspicion_n of_o its_o insufficiency_n which_o be_v these_o 1._o i_o observe_v that_o all_o learned_a man_n be_v to_o this_o day_n high_o dissatisfy_v as_o to_o the_o cause_n and_o manner_n of_o the_o operation_n of_o opium_n notwithstanding_o all_o that_o have_v be_v write_v concern_v it_o and_o that_o it_o be_v the_o common_a cry_n on_o all_o hand_n that_o none_o have_v illustrate_v the_o operation_n of_o opium_n to_o any_o purpose_n or_o give_v any_o satisfaction_n therein_o and_o therefore_o learned_a physician_n be_v still_o as_o much_o upon_o the_o enquiry_n as_o ever_o they_o be_v it_o be_v much_o more_o civil_a and_o reasonable_a to_o suspect_v the_o foundation_n that_o all_o former_a author_n have_v build_v upon_o than_o a_o general_a failure_n in_o all_o the_o most_o judicious_a master_n builder_n that_o ever_o endeavour_v to_o build_v thereon_o for_o if_o all_o the_o best_a architect_n of_o the_o whole_a world_n fail_v to_o erect_v a_o firm_a superstructure_n upon_o any_o one_o foundation_n what_o can_v we_o think_v but_o that_o the_o foundation_n be_v infirm_a especial_o when_o as_o in_o our_o case_n no_o way_n that_o care_n judgement_n perspicacity_n and_o wit_n can_v invent_v or_o think_v of_o have_v be_v leave_v untried_a to_o build_v thereon_o so_o that_o though_o i_o modest_o call_v it_o a_o cause_n of_o suspicion_n it_o amount_v almost_o if_o not_o altogether_o to_o a_o demonstration_n that_o the_o foundation_n that_o all_o author_n have_v go_v upon_o be_v naught_o will_v not_o any_o consider_a man_n when_o he_o see_v all_o the_o judicious_a architect_n of_o the_o world_n fail_v to_o erect_v a_o firm_a building_n upon_o a_o certain_a foandation_n seek_v for_o another_o therefore_o who_o can_v blame_v i_o if_o i_o do_v and_o not_o blame_v they_o that_o do_v not_o the_o mean_a bricklayer_n or_o carpenter_n that_o shall_v be_v guilty_a of_o such_o stupidity_n as_o to_o attempt_v to_o build_v upon_o such_o a_o foundation_n as_o always_o deceive_v the_o builder_n will_v be_v think_v too_o great_a a_o blockhead_n to_o be_v employ_v in_o building_n 2._o i_o observe_v that_o most_o man_n do_v notwithstanding_o that_o foundation_n be_v agree_v upon_o think_v it_o impossible_a to_o explain_v the_o intricate_a various_a contradictory_n phenomena_n and_o mysterious_a effect_n of_o opium_n sit_v content_v and_o persuade_v that_o it_o operate_v by_o a_o occult_a quality_n whole_o unexplicable_a and_o particular_o reserve_v from_o the_o knowledge_n of_o mankind_n but_o nature_n work_v mechanical_o in_o weight_n measure_n etc._n etc._n therefore_o it_o be_v more_o than_o probable_a that_o it_o be_v only_o their_o be_v upon_o a_o wrong_a bottom_n make_v it_o seem_v absolute_o occult_a for_o it_o be_v impossible_a to_o find_v a_o thing_n where_o it_o be_v not_o or_o to_o build_v firm_o upon_o a_o insufficient_a foundation_n whereas_o have_v it_o be_v right_o and_o true_a it_o be_v not_o to_o be_v imagine_v but_o some_o or_o other_o will_v have_v thereupon_o do_v something_o that_o will_v have_v stand_v against_o all_o wind_n and_o storm_n which_o none_o have_v do_v 3._o i_o observe_v that_o none_o dare_v venture_v to_o lay_v the_o whole_a no_o nor_o one_o half_a of_o the_o burden_n of_o the_o phinomena_n or_o effect_n of_o opium_n upon_o that_o foundation_n foresee_v doubtless_o that_o it_o can_v not_o bear_v they_o and_o that_o if_o they_o lay_v any_o more_o weight_n thereon_o the_o whole_a will_v totter_v and_o fall_v to_o the_o ground_n the_o project_n in_o every_o hypothesis_n be_v to_o persuade_v man_n of_o the_o truth_n thereof_o and_o the_o only_a way_n to_o do_v it_o be_v to_o solve_v all_o phenomena_n thereby_o for_o if_o it_o fail_v but_o in_o one_o it_o be_v a_o infallible_a sign_n of_o its_o insufficiency_n there_o be_v no_o reason_n to_o omit_v any_o of_o the_o phenomena_n if_o they_o can_v have_v discern_v that_o the_o hypothesis_n will_v have_v bear_v they_o therefore_o as_o have_v be_v intimate_v it_o imply_v a_o confession_n of_o its_o incompetency_n 4._o i_o observe_v that_o ancient_a author_n write_v of_o opium_n before_o it_o come_v to_o be_v of_o common_a and_o general_a use_n in_o the_o daytime_n with_o healthy_a person_n as_o it_o since_o be_v in_o many_o nation_n to_o cause_v a_o gay_a pleasant_a and_o good_a humour_n take_v off_o sadness_n melancholy_a and_o anxiety_n to_o cause_n assurance_n boldness_n courage_n bravery_n magnanimity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n promptitude_n in_o business_n expediteness_n and_o serenity_n to_o excite_v to_o venery_n etc._n etc._n which_o effect_n can_v be_v explain_v by_o that_o supposition_n of_o disable_n the_o spirit_n and_o that_o they_o use_v opium_n only_a medicinally_n for_o the_o sake_n of_o such_o other_o effect_n as_o may_v be_v tolerable_o well_o explicate_v by_o that_o hypothesis_n so_o that_o they_o have_v not_o any_o occasion_n nor_o inducement_n to_o look_v any_o far_o the_o effect_n they_o give_v it_o for_o be_v only_o 1._o to_o cause_v sleep_n 2._o to_o take_v off_o pain_n 3._o to_o stop_v flux_n 4._o to_o compose_v the_o spirit_n 5._o to_o cause_v perspiration_n and_o sweat_n all_o which_o be_v not_o inconsistent_a with_o the_o hypothesis_n of_o diminish_v or_o disable_n the_o spirit_n as_o the_o other_o be_v and_o therefore_o may_v well_o deceive_v they_o for_o first_o sleep_n be_v cause_v by_o diminish_v the_o spirit_n by_o labour_n watch_v etc._n etc._n as_o be_v most_o notorious_a over_o the_o whole_a world_n so_o other_o thing_n that_o diminish_v the_o spirit_n as_o bleed_v vomit_v purge_v and_o many_o other_o cause_n of_o diminish_v thereof_o do_v incline_v we_o to_o sleep_v second_o indolence_n or_o exemption_n from_o pain_n be_v cause_v by_o nothing_o more_o than_o want_v of_o spirit_n as_o in_o paralytical_a case_n stuporâ—_n obstruction_n or_o compression_n of_o the_o nerve_n syncopes_fw-la leipothymy_n deliquium_n faint_n after_o bleed_v and_o sleep_v which_o as_o be_v say_v be_v so_o much_o cause_v by_o loss_n of_o spirit_n etc._n etc._n three_o flux_n be_v stop_v or_o moderate_v by_o nothing_o better_a than_o sleep_n which_o general_o as_o be_v say_v proceed_v from_o loss_n of_o spirit_n what_o also_o stop_v or_o moderate_v flux_n more_o than_o want_v of_o the_o sense_n of_o the_o irritation_n of_o humour_n and_o what_o take_v away_o sense_n more_o than_o want_v of_o spirit_n thus_o want_v of_o sense_n by_o the_o absence_n of_o the_o spirit_n in_o paralytical_a intestine_n stop_v flux_n thus_o fail_v a_o paralytical_a bladder_n to_o express_v the_o urine_n so_o a_o palsy_n of_o the_o membrane_n
that_o include_v the_o glandule_n must_v as_o in_o sleep_n which_o relax_n they_o stop_v or_o moderate_v all_o defluxion_n catarrh_n etc._n etc._n because_o they_o be_v not_o sensible_a oâ—_n the_o irritation_n of_o the_o humour_n by_o quantity_n or_o quality_n which_o irritation_n cause_v the_o defluxion_n or_o catarrh_n by_o exciting_a the_o membrane_n to_o contract_v and_o thereby_o to_o squeeze_v out_o the_o humour_n contain_v in_o the_o glandule_n four_o the_o composure_n of_o the_o spirit_n be_v procure_v main_o by_o sleep_n which_o all_o loss_n of_o spirit_n as_o be_v show_v incline_v we_o to_o so_o bleed_v which_o diminish_v the_o spirit_n compose_v their_o fury_n in_o fever_n delirium_n madness_n etc._n etc._n five_o perspiration_n be_v cause_v by_o nothing_o more_o than_o sleep_v for_o we_o perspire_v twice_o as_o much_o in_o sleep_n as_o when_o we_o watch_v as_o be_v most_o manifest_o demonstrable_a by_o the_o statick_a experiment_n of_o weigh_v people_n nor_o be_v perspiration_n ever_o so_o great_a as_o in_o deliquium_n syncopes_fw-la leipothymy_n and_o such_o like_a deadish_fw-mi case_n which_o be_v cause_v by_o diminish_v or_o disable_n of_o the_o spirit_n nay_o it_o be_v so_o in_o animal_n quite_o dead_a for_o a_o little_a time_n while_o they_o be_v hot_a as_o be_v evident_a by_o like_a statick_a demonstration_n the_o true_a cause_n of_o which_o be_v relaxation_n of_o the_o pore_n skin_n etc._n etc._n for_o want_n of_o spirit_n to_o contract_n and_o constringe_v they_o as_o shall_v be_v full_o prove_v hereafter_o by_o god_n help_n these_o thing_n be_v doubtless_o the_o occasion_n of_o that_o hypothesis_n of_o diminish_v or_o disable_n the_o spirit_n by_o opium_n but_o how_o likely_a be_v they_o to_o err_v by_o establish_v it_o without_o any_o consideration_n of_o its_o enliven_a encourage_v and_o brisk_a effect_n as_o ovation_n of_o the_o spirit_n gaity_n bravery_n magnanimity_n euphory_n promptitude_n to_o venery_n etc._n etc._n which_o can_v never_o be_v solve_v by_o diminution_n or_o disability_n of_o the_o spirit_n till_o depression_n and_o elevation_n thereof_o be_v reconcilable_a and_o consistent_a at_o the_o same_o time_n in_o the_o same_o subject_n which_o can_v never_o be_v till_o disable_n and_o not_o disable_n be_v the_o same_o thing_n have_v not_o we_o then_o good_a reason_n to_o suspect_v that_o general_a foundation_n of_o diminish_v or_o disable_n the_o spirit_n by_o opium_n which_o be_v lay_v by_o such_o as_o never_o consider_v any_o thing_n of_o its_o generous_a and_o sprightly_a effect_n which_o as_o have_v be_v show_v be_v its_o constant_a and_o therefore_o most_o proper_a and_o genuine_a effect_n who_o can_v doubt_v then_o but_o they_o must_v err_v in_o lay_v a_o foundation_n quite_o contrary_a to_o the_o very_a property_n of_o opium_n 5._o i_o observe_v that_o all_o our_o modern_a author_n and_o physician_n receive_v the_o knowledge_n of_o opium_n its_o effect_n and_o uses_n from_o those_o ancient_n do_v use_v it_o only_o for_o the_o same_o end_n and_o purpose_v as_o they_o do_v and_o that_o our_o modern_a author_n live_v in_o these_o western_a part_n of_o the_o world_n very_o remote_a from_o the_o eastern_a country_n where_o it_o be_v use_v common_o and_o in_o large_a dose_n by_o people_n in_o health_n in_o the_o daytime_n to_o enliven_v invigorate_a and_o encourage_v they_o and_o cause_v the_o brave_a generous_a and_o magnanimous_a effect_n aforemention_v viz._n courage_n euphory_n etc._n etc._n and_o find_v no_o physician_n that_o go_v before_o they_o to_o mention_v these_o noble_a cordial_a and_o glorious_a effect_n and_o if_o they_o do_v at_o any_o time_n slight_o touch_v they_o to_o do_v it_o with_o all_o imaginable_a disregard_n neglect_v and_o contempt_n as_o if_o there_o be_v no_o heed_n to_o be_v take_v of_o they_o but_o as_o idle_a tale_n and_o improbable_a story_n be_v contrary_a and_o utter_o as_o they_o think_v inconsistent_a and_o irreconcilable_a with_o the_o daily_a and_o most_o notorious_a effect_n of_o opium_n observe_v among_o we_o and_o to_o the_o universal_a opinion_n of_o all_o author_n who_o state_v opium_n to_o be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n which_o can_v not_o produce_v as_o they_o conclude_v such_o contradictory_n and_o therefore_o to_o they_o utter_o incredible_a effect_n and_o fabulons_a flam_n arise_v as_o they_o fancy_v from_o some_o silly_a error_n as_o want_v of_o due_a observation_n in_o traveller_n mistake_a discourse_n and_o the_o like_a so_o that_o as_o the_o say_n be_v they_o let_v they_o in_o at_o one_o ear_n and_o out_o at_o the_o other_o there_o be_v no_o such_o contrary_a effect_n of_o any_o one_o thing_n to_o be_v observe_v in_o the_o whole_a creation_n and_o they_o be_v well_o assure_v of_o the_o other_o effect_n by_o daily_a experience_n and_o have_v never_o observe_v those_o lively_a effect_n for_o the_o several_a plain_a reason_n that_o you_o will_v meet_v in_o the_o follow_a paragraph_n have_v no_o cause_n to_o alter_v their_o opinion_n when_o all_o thing_n seem_v to_o they_o to_o make_v for_o their_o hypothesis_n for_o want_v of_o a_o notion_n of_o those_o brisk_a effect_n 6._o i_o observe_v that_o those_o brisk_a effect_n of_o opium_n be_v not_o take_v notice_n of_o by_o our_o physician_n nor_o indeed_o all_o thing_n consider_v do_v i_o well_o see_v how_o they_o shall_v without_o get_v out_o of_o the_o common_a road_n of_o observe_v which_o be_v sometime_o as_o i_o have_v find_v very_o useful_a upon_o such_o occasion_n for_o first_o opium_n be_v seldom_o if_o ever_o give_v in_o these_o western_a nation_n but_o to_o sick_a people_n as_o the_o ancient_n do_v who_o be_v utter_o incapable_a of_o those_o brisk_a effect_n or_o at_o least_o to_o any_o remarkable_a degree_n that_o may_v call_v for_o a_o particular_a or_o special_a advertency_n or_o attention_n without_o which_o they_o pass_v off_o as_o they_o come_v without_o any_o reflection_n thereupon_o and_o so_o signify_v nothing_o as_o if_o they_o have_v never_o happen_v second_o we_o as_o the_o ancient_n do_v general_o give_v opium_n when_o people_n be_v go_v to_o bed_n by_o which_o mean_v all_o opportunity_n of_o observation_n be_v lose_v because_o darkness_n and_o be_v alone_o hide_v or_o hinder_v the_o show_v of_o any_o such_o effect_n and_o the_o physician_n who_o only_a business_n it_o be_v to_o be_v more_o curious_a in_o such_o matter_n be_v go_v to_o his_o own_o rest_n though_o if_o he_o be_v present_a not_o likely_a to_o take_v any_o observation_n of_o such_o matter_n whereof_o he_o have_v least_o thought_n or_o belief_n as_o be_v in_o his_o opinion_n contrary_a to_o all_o reason_n sense_n experience_n and_o the_o opinion_n of_o all_o author_n of_o the_o stupefactive_a quality_n of_o opium_n in_o which_o they_o all_o agree_v three_o opium_n be_v as_o be_v say_v give_v in_o these_o country_n to_o cause_n sleep_n or_o such_o effect_n to_o which_o sleep_n conduce_v as_o compose_v the_o spirit_n cause_v indolence_n stop_v flux_n and_o promote_a perspiration_n and_o therefore_o always_o give_v with_o all_o careful_a direction_n and_o injunction_n that_o may_v conduce_v to_o that_o end_n as_o go_v to_o bed_n lie_v still_o put_v out_o light_n keep_v silence_n etc._n etc._n which_o concur_v with_o the_o opium_n cause_n sleep_n which_o be_v utter_o inconsistent_a with_o show_v any_o of_o those_o lively_a effect_n that_o belong_v only_o to_o a_o wake_a person_n to_o do_v so_o that_o all_o opportunity_n of_o observation_n be_v utter_o preclude_v now_o all_o the_o premise_n consider_v it_o can_v be_v conceive_v that_o such_o as_o set_v their_o mind_n upon_o contrary_a effect_n and_o expect_v no_o other_o much_o less_o contrary_a one_o against_o which_o also_o they_o be_v high_o prejudice_v by_o their_o reason_n experience_n and_o read_v shall_v observe_v such_o brisk_a effect_n if_o they_o do_v happen_v and_o how_o can_v a_o brisk_a humour_n courage_n easy_a undergo_n of_o labour_n promptitude_n to_o venus_n etc._n etc._n be_v observe_v in_o sick_a and_o infirm_a people_n lie_v in_o bed_n alone_z and_o in_o the_o dark_a or_o which_o render_v it_o utter_o impossible_a while_o they_o be_v asleep_a and_o the_o thing_n itself_o disbelieved_a and_o esteem_v contrary_a to_o common_a sense_n and_o the_o universal_a sentiment_n of_o the_o learned_a and_o all_o other_o therefore_o 7._o if_o after_o all_o any_o such_o brisk_a effect_n do_v ever_o happen_v it_o must_v be_v either_o not_o regard_v or_o if_o observe_v which_o be_v no_o way_n likely_a as_o be_v show_v you_o may_v be_v sure_a for_o the_o many_o plain_a reason_n and_o cause_n aforesaid_a that_o it_o be_v not_o impute_v to_o stupify_a opium_n as_o all_o esteem_v it_o but_o to_o any_o other_o cause_n or_o accident_n rather_o than_o to_o a_o thing_n well_o know_v to_o have_v quite_o contrary_a effect_n for_o instance_n if_o the_o sick_a person_n happen_v to_o be_v
increase_v more_o and_o more_o and_o make_v one_o more_o and_o more_o remote_a from_o wake_v 4._o why_o shall_v warm_a bath_n fomentation_n feetwash_n head-washes_a warm_a moist_a wether_n the_o act_n of_o venery_n the_o pleasure_n of_o sweet_a melody_n gentle_a rub_v of_o the_o head_n in_o a_o pleasant_a manner_n scratch_v the_o back_n where_o it_o itch_v and_o all_o gentle_a pleasure_n that_o be_v consistent_a with_o lie_v or_o sit_v still_o which_o do_v all_o cause_n a_o very_a free_a perspiration_n of_o fume_n at_o the_o pore_n that_o be_v then_o most_o certain_o open_v by_o all_o those_o cause_n as_o may_v be_v prove_v by_o statick_a demonstration_n magnify_v glass_n etc._n etc._n cause_n sleep_n see_v they_o all_o cause_n a_o spend_v of_o the_o fume_n obj._n some_o half-witted_a unthinking_a caviller_n may_v say_v that_o such_o thing_n stir_v up_o the_o vapour_n etc._n etc._n answ._n what_o such_o mean_a by_o vapour_n stir_v be_v not_o easy_o determinable_a but_o this_o i_o know_v that_o all_o stir_n of_o humour_n or_o any_o other_o thing_n hinder_v sleep_n and_o that_o the_o long_o such_o cause_n of_o open_v the_o pore_n and_o consequent_o of_o perspire_a fume_n do_v last_o the_o more_o we_o be_v incline_v by_o they_o to_o sleep_n so_o that_o the_o more_o our_o fume_n have_v be_v spend_v the_o more_o we_o be_v incline_v to_o sleep_v which_o be_v a_o strange_a contradiction_n if_o fume_n be_v the_o cause_n of_o sleep_n i_o can_v but_o smile_v to_o think_v how_o most_o physician_n come_v to_o call_v several_a thing_n vapour_n first_o they_o say_v that_o sleep_n be_v from_o vapour_n then_o call_v every_o thing_n vapour_n right_a or_o wrong_n that_o incline_v we_o to_o sleep_v by_o reason_n of_o that_o false_a supposition_n how_o then_o come_v camphire_n not_o to_o be_v a_o great_a causer_n of_o sleep_n that_o be_v so_o apt_a to_o evaporate_v 5._o fear_v sorrow_n grief_n melancholy_n depression_n of_o spirit_n cold_a etc._n etc._n do_v most_o certain_o close_v the_o pore_n as_o appear_v by_o statick_a experiment_n by_o which_o mean_v vapour_n be_v much_o crowd_v in_o the_o body_n yet_o all_o such_o grievance_n do_v hinder_v sleep_n as_o they_o also_o do_v the_o effect_n of_o opium_n and_o drunkenness_n therefore_o they_o do_v not_o proceed_v from_o fume_n as_o the_o world_n imagine_v for_o then_o these_o thing_n that_o crowd_v in_o the_o fume_n and_o vapour_n will_v promote_v not_o hinder_v sleep_n 6._o if_o fume_n be_v the_o cause_n of_o sleep_n then_o be_v the_o cause_n of_o sleep_n and_o vertigo_n as_o the_o vaporanians_n allow_v the_o same_o it_o follow_v then_o that_o we_o can_v never_o sleep_v without_o a_o vertigo_n 7._o many_o as_o dr._n willis_n say_v eat_v their_o meat_n take_v their_o drink_n etc._n etc._n as_o other_o people_n yet_o do_v not_o sleep_v at_o all_o for_o many_o week_n together_o which_o be_v impossible_a if_o the_o fume_n of_o meat_n and_o drink_v cause_v sleep_n for_o they_o by_o eat_v and_o drink_v must_v have_v those_o fume_n and_o consequent_o sleep_v as_o other_o people_n if_o that_o be_v true_a three_o they_o suppose_v and_o take_v it_o for_o grant_v which_o i_o do_v not_o for_o i_o know_v the_o contrary_a that_o opium_n while_o it_o be_v at_o stomach_n can_v affect_v the_o brain_n etc._n etc._n no_o other_o way_n but_o by_o fume_n which_o be_v a_o most_o groundless_a supposition_n for_o 1._o how_o shall_v a_o lump_n of_o curd_n at_o stomach_n or_o the_o have_v of_o a_o knife_n swallow_v and_o many_o such_o thing_n which_o can_v send_v no_o fume_n to_o the_o head_n cause_n convulsion_n headache_n vertigo_n syncopes_fw-la leipothymy_n of_o the_o whole_a man_n manias_fw-la furor_n etc._n etc._n if_o there_o be_v not_o another_o way_n for_o thing_n to_o affect_v the_o nervosum_fw-la genus_fw-la etc._n etc._n while_n at_o stomach_n beside_o send_v up_o vapour_n to_o do_v it_o but_o of_o this_o matter_n to_o show_v how_o a_o thing_n at_o stomach_n may_v affect_v the_o brain_n and_o the_o whole_a system_n of_o the_o nerve_n etc._n etc._n and_o how_o opium_n do_v it_o without_o fume_n the_o 17_o 18_o 19_o 20_o etc._n etc._n chapter_n will_v show_v you_o at_o large_a therefore_o i_o shall_v say_v no_o more_o of_o this_o at_o present_a for_o it_o be_v fit_a for_o we_o first_o to_o overthrow_v that_o supposition_n of_o fume_n and_o vapour_n before_o we_o establish_v our_o own_o for_o far_a satisfaction_n then_o as_o to_o that_o general_a supposition_n of_o fume_n let_v we_o due_o and_o full_o consider_v thing_n for_o it_o be_v not_o a_o slight_a matter_n to_o proceed_v against_o a_o general_n opinion_n that_o have_v continue_v through_o all_o age_n or_o to_o wipe_v off_o the_o prejudices_fw-la acquire_v thereby_o observe_v 1._o that_o the_o brain_n be_v a_o principal_a part._n 2._o that_o it_o be_v very_o soft_a tender_a and_o next_o to_o a_o fluid_a 3._o that_o very_o small_a fine_a and_o gentle_a thing_n do_v high_o offend_v it_o as_o the_o effluvia_n of_o sweet_a or_o ill-scented_n thing_n cause_v hysterick_a and_o epileptical_a fit_n syncopes_fw-la faint_n etc._n etc._n it_o be_v also_o notorious_a among_o we_o physician_n that_o a_o little_a fume_v scarce_o sensible_a as_o to_o quantity_n or_o quality_n rise_v from_o a_o toe_n finger_n &c_n &c_n and_o arrive_v at_o the_o brain_n cause_v dreadful_a epileptical_a fit_n vertigo_n &c._n &c._n 4._o that_o our_o wise_a and_o provident_a creator_n have_v therefore_o secure_v and_o fortify_v all_o the_o avenue_n of_o the_o brain_n in_o a_o more_o particular_a manner_n by_o several_a circumvallation_n viz._n first_o with_o the_o pia_fw-la mater_fw-la second_o with_o the_o dura_n mater_n call_v so_o from_o its_o hardness_n solidity_n and_o strength_n three_o with_o a_o strong_a skull_n of_o a_o round_a or_o arch_a figure_n four_o with_o the_o pericranium_n all_o which_o belong_v to_o it_o particular_o beside_o other_o integument_n common_a to_o it_o with_o other_o part_n as_o 1._o the_o skin_n 2._o the_o cuticle_n 3._o the_o membrana_fw-la carnosa_fw-la 4._o the_o periostium_fw-la all_o which_o do_v surround_v it_o and_o after_o all_o it_o be_v thatch_v as_o it_o be_v with_o hair_n 5._o that_o the_o same_o providence_n have_v take_v care_n which_o be_v very_o observable_a that_o none_o of_o the_o object_n of_o sensation_n nor_o probable_o any_o particle_n or_o effluvium_fw-la that_o fly_v from_o they_o shall_v ever_o reach_v the_o brain_n but_o only_o bare_a impulse_n and_o they_o not_o immediate_o convey_v but_o by_o the_o intervention_n of_o a_o fine_a tenuious_a soft_a gentle_a and_o most_o agreeable_a aura_n viz._n the_o animal_n spirit_n lest_o any_o offence_n shall_v be_v give_v in_o the_o least_o manner_n to_o this_o most_o tender_a delicate_a principal_a part_n and_o royal_a seat_n of_o the_o soul_n all_o which_o care_n have_v never_o be_v without_o necessity_n for_o god_n and_o nature_n do_v nothing_o in_o vain_a and_o if_o you_o will_v due_o consider_v the_o organ_n of_o sensation_n that_o be_v near_o the_o brain_n you_o will_v find_v that_o they_o be_v contrive_v as_o shutter_n to_o exclude_v all_o extraneous_a particle_n from_o the_o brain_n for_o impulse_n may_v have_v be_v contrive_v without_o their_o intervention_n because_o they_o do_v not_o alter_v or_o improve_v the_o impulse_n receive_v from_o object_n for_o if_o they_o do_v we_o shall_v not_o have_v true_a notice_n of_o thing_n and_o see_v they_o do_v not_o alter_v or_o improve_v the_o impulse_n of_o what_o use_n shall_v they_o be_v but_o to_o exclude_v extraneous_a particle_n eume_n effluvia_n &c._n &c._n for_o instance_n the_o tremulous_a motion_n of_o the_o air_n in_o the_o case_n of_o sound_n will_v have_v as_o true_o hit_v the_o auditory_a nerve_n or_o membrane_n without_o the_o tympan_n and_o very_o often_o much_o true_a without_o it_o because_o of_o the_o several_a fault_n and_o disorder_n that_o it_o be_v liable_a to_o yet_o so_o necessary_a be_v it_o think_v by_o the_o best_a of_o judge_n who_o can_v err_v that_o it_o be_v rather_o to_o be_v place_v there_o with_o all_o its_o inconvenience_n that_o may_v follow_v than_o any_o way_n expose_v the_o brain_n though_o to_o the_o most_o gentle_a of_o body_n viz._n the_o air_n by_o which_o in_o all_o probability_n the_o animal_n spirit_n themselves_o be_v nourish_v or_o sustain_v be_v it_o not_o that_o extraneous_a particle_n or_o air_n will_v offend_v the_o brain_n what_o need_n be_v there_o of_o the_o tympan_n when_o we_o know_v as_o well_o by_o experience_n as_o by_o the_o aforesaid_a reason_n that_o a_o dog_n etc._n etc._n can_v hear_v as_o well_o without_o it_o upon_o the_o first_o take_v it_o off_o but_o that_o the_o hear_v will_v afterward_o decay_v because_o the_o brain_n etc._n etc._n be_v expose_v will_v be_v injure_v what_o be_v evident_a in_o the_o case_n of_o the_o ear_n may_v be_v make_v so_o
the_o spirit_n by_o any_o mean_n for_o there_o be_v nothing_o so_o good_a in_o nature_n but_o will_v do_v it_o if_o use_v undue_o or_o immoderate_o as_o wine_n bread_n milk_n honey_n sugar_n beer_n etc._n etc._n in_o excess_n for_o i_o intend_v that_o it_o do_v not_o do_v it_o when_o due_o and_o moderate_o use_v 1._o that_o which_o refresh_v the_o weary_a and_o high_o prevent_v weariness_n must_v add_v to_o or_o excite_v the_o spirit_n which_o be_v direct_o contrary_a to_o diminish_v or_o disable_n they_o but_o opium_n do_v in_o a_o most_o eminent_a manner_n refresh_v the_o weary_v and_o prevent_v weariness_n therefore_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n some_o have_v be_v so_o silly_a and_o inadvertent_n as_o to_o object_n that_o it_o refresh_v the_o weary_a only_o by_o sleep_n it_o be_v matter_n of_o fact_n that_o it_o refresh_v they_o whether_o they_o sleep_v or_o no_o and_o that_o without_o fail_v as_o often_o as_o it_o be_v use_v in_o that_o case_n other_o that_o be_v no_o wise_a have_v say_v that_o it_o only_o take_v off_o the_o sense_n of_o weariness_n by_o stupify_a which_o happen_v by_o the_o diminish_n or_o disable_n of_o the_o animal_n spirit_n bare_a insensibleness_n can_v enable_v the_o spirit_n to_o labour_n with_o eminent_a briskness_n and_o alacrity_n as_o man_n most_o certain_o do_v after_o opium_n be_v take_v be_v fine_o enliven_v and_o invigorate_v as_o with_o generous_a wine_n if_o they_o do_v not_o know_v this_o to_o be_v true_a let_v they_o for_o shame_n hold_v their_o tongue_n till_o they_o know_v matter_n of_o fact_n which_o if_o they_o will_v not_o they_o proclaim_v themselves_o to_o be_v idle_a and_o impertinent_a babbler_n but_o if_o they_o will_v patient_o and_o wise_o abstain_v argue_v till_o they_o be_v satisfy_v as_o to_o matter_n of_o fact_n then_o will_v they_o be_v past_a opinion_n and_o hypothesis_n in_o that_o case_n for_o they_o will_v have_v sensible_a and_o certain_a knowledge_n of_o the_o contrary_a and_o the_o truth_n of_o what_o i_o say_v which_o will_v end_v all_o controversy_n and_o precarious_a squabble_n upon_o false_a supposition_n as_o the_o manner_n be_v that_o can_v lead_v they_o to_o what_o be_v right_o but_o by_o mere_a chance_n and_o never_o to_o a_o true_a knowledge_n that_o they_o be_v in_o the_o right_n which_o make_v it_o none_o in_o effect_n for_o they_o can_v do_v nothing_o with_o assurance_n but_o only_o suppose_v and_o hope_v they_o be_v in_o the_o right_n when_o they_o be_v as_o much_o out_o to_o their_o patient_n sorrow_n as_o physician_n have_v be_v in_o the_o cold_a quality_n and_o fume_n of_o opium_n it_o be_v true_a that_o a_o grain_n or_o two_o of_o opium_n will_n if_o a_o man_n compose_v himself_o sit_v or_o lie_v still_o cause_n a_o sleepiness_n equal_a to_o that_o cause_v by_o spend_v the_o spirit_n by_o a_o day_n be_v labour_n but_o spend_v of_o the_o spirit_n be_v not_o the_o only_a no_o nor_o best_a proportion_v or_o more_o adequate_a cause_n thereof_o as_o i_o have_v show_v if_o loss_n of_o spirit_n be_v the_o adequate_a cause_n of_o sleep_n how_o shall_v good_a and_o generous_a wine_n cause_n sleepiness_n after_o that_o eminent_a rate_n as_o it_o do_v in_o most_o people_n how_o shall_v the_o most_o please_a music_n incline_v such_o as_o lie_v or_o sit_v still_o to_o sleep_v but_o if_o one_o dance_n thereto_o it_o make_v he_o more_o lively_a and_o brisk_a than_o ordinary_a the_o like_a exact_o do_v wine_n and_o opium_n if_o man_n lie_v or_o sit_v still_o but_o otherwise_o they_o make_v they_o much_o more_o brisk_a and_o lively_a and_o able_a to_o undergo_v labour_n action_n etc._n etc._n which_o note_n that_o you_o may_v not_o any_o more_o wonder_n that_o enlivener_n and_o exciter_n of_o the_o spirit_n do_v cause_n sleep_v as_o well_o as_o diminisher_n thereof_o and_o observe_v that_o they_o be_v all_o please_a thing_n as_o music_n wine_n and_o opium_n which_o cause_n pleasant_a dream_n pleasant_a watch_n pleasant_a humour_n etc._n etc._n expect_v more_o of_o this_o matter_n in_o the_o follow_a chapter_n and_o all_o by_o degree_n according_a as_o i_o judge_v the_o prejudice_v world_n will_v bear_v thing_n for_o a_o great_a paradox_n how_o true_a soever_o must_v not_o be_v abrupt_o obtrude_v but_o gentle_o and_o gradual_o usher_v in_o by_o insinuate_v reason_v otherwise_o it_o will_v be_v entertain_v like_o a_o rude_a stranger_n that_o contradict_v a_o multitude_n in_o fashion_n and_o custom_n that_o they_o have_v always_o use_v and_o judge_v to_o be_v the_o very_o best_o however_o unblamable_a consider_v that_o if_o opium_n diminish_v or_o disable_v the_o spirit_n proportionable_a to_o the_o sleepiness_n that_o it_o cause_n as_o a_o hard_a day_n be_v labour_n do_v then_o if_o opium_n be_v give_v a_o man_n after_o a_o hard_a day_n be_v labour_n it_o will_v be_v as_o it_o be_v add_v another_o hard_a day_n be_v labour_v to_o cure_v it_o the_o day_n be_v labour_n and_o opium_n impair_n the_o spirit_n alike_o think_v what_o a_o miserable_a condition_n the_o poor_a man_n will_v be_v in_o especial_o if_o sleep_n do_v not_o make_v he_o some_o amends_o it_o will_v be_v such_o as_o be_v utter_o intolerable_a but_o so_o far_o be_v opium_n from_o any_o such_o effect_n that_o it_o refresh_v he_o though_o he_o sleep_v not_o at_o all_o after_o the_o hard_a day_n be_v labour_n and_o not_o only_o so_o but_o will_v enable_v he_o to_o work_v all_o the_o follow_a night_n with_o great_a alacrity_n if_o need_n require_v it_o what_o a_o condition_n will_v those_o be_v in_o who_o take_v a_o drachm_n of_o it_o twice_o a_o day_n for_o 10_o 20_o or_o 30_o year_n nay_o how_o can_v any_o possible_o do_v it_o for_o half_a 10_o day_n if_o a_o grain_n or_o two_o destroy_v the_o spirit_n so_o much_o as_o to_o cause_v sleepiness_n thereby_o as_o hard_a labour_n do_v which_o they_o must_v allow_v that_o assert_v it_o cause_n sleep_v by_o diminish_v or_o disable_n the_o spirit_n but_o some_o may_v say_v though_o very_o inconsiderate_o that_o it_o only_o disable_v they_o for_o the_o time_n of_o its_o operation_n that_o be_v strange_a indeed_o consider_v that_o even_o during_o that_o time_n they_o be_v most_o enable_v to_o work_n or_o labour_n though_o tire_v before_o and_o that_o it_o 2._o cause_n comfort_n refreshment_n ovation_n of_o the_o spirit_n all_o the_o time_n of_o its_o operation_n as_o wine_n moderate_o take_v do_v especial_o if_o people_n keep_v themselves_o in_o action_n labour_n etc._n etc._n otherwise_o indeed_o they_o may_v fall_v asleep_a upon_o the_o comfortable_a satisfaction_n contentation_n of_o mind_n and_o acquiescence_n of_o spirit_n that_o it_o occasion_n as_o wine_n do_v 3._o the_o first_o effect_n that_o we_o find_v of_o opium_n which_o may_v therefore_o probable_o be_v a_o very_a lead_n fundamental_a and_o significant_a effect_n be_v that_o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o incline_v he_o to_o sleep_n if_o not_o it_o make_v he_o gay_a good_a humour_a brave_a etc._n etc._n it_o be_v a_o pleasure_n so_o sweet_a and_o delicious_a that_o though_o i_o endeavour_v to_o express_v it_o by_o the_o ovation_n of_o the_o spirit_n upon_o joy_n a_o good_a genius_n inform_v a_o man_n or_o the_o helmâ—sians_n archaeus_n in_o his_o best_a humour_n or_o a_o continual_a vâ—real_a pleasure_n wine_n drink_v ad_fw-la hilaritatem_fw-la etc._n etc._n yet_o i_o doubt_v all_o my_o way_n of_o express_v it_o do_v come_v short_a of_o the_o charm_a complacency_n that_o it_o cause_n therefore_o if_o wine_n music_n a_o good_a meal_n agreeable_a frication_n of_o the_o head_n or_o back_o the_o sound_n of_o water_n etc._n etc._n do_v incline_v we_o to_o sleep_v by_o the_o pleasure_n thereof_o which_o lull_v and_o soothe_v we_o to_o it_o as_o be_v most_o certain_a if_o we_o sit_v or_o lie_v still_o much_o more_o must_v the_o high_a charm_n of_o opium_n cause_n it_o that_o it_o be_v a_o pleasure_n that_o affect_v by_o one_o of_o our_o sense_n namely_o by_o feel_v be_v indisputable_a for_o it_o be_v not_o a_o pleasure_n of_o the_o eye_n nose_n tongue_n or_o ear_n and_o it_o must_v be_v sensitive_a because_o cause_v by_o matter_n and_o that_o opium_n have_v doubtless_o the_o like_a effect_n upon_o brute_n who_o have_v no_o other_o pleasure_n but_o what_o be_v sensitive_a that_o it_o be_v at_o stomach_n be_v also_o evident_a where_o we_o can_v be_v please_v only_o by_o the_o sense_n of_o feel_v that_o it_o be_v involuntary_a and_o please_v we_o whether_o we_o will_v or_o no_o and_o that_o the_o same_o particle_n excite_v venery_n itch_a etc._n etc._n now_o all_o the_o sense_n especial_o feel_v and_o particular_o that_o at_o stomach_n be_v give_v we_o for_o
only_o the_o open_n of_o the_o pore_n so_o that_o i_o need_v add_v no_o more_o word_n about_o it_o for_o the_o fame_n cause_o must_v have_v the_o same_o effect_n therefore_o a_o intense_a and_o permanent_a pleasure_n must_v have_v all_o or_o much_o of_o the_o effect_n of_o sleep_n in_o general_n as_o have_v be_v show_v it_o can_v therefore_o be_v any_o wonder_n that_o opium_n cause_v sleep_n yet_o be_v there_o difference_n between_o sleep_n and_o pleasure_n upon_o other_o account_n though_o not_o upon_o the_o account_n of_o relaxation_n viz._n because_o 1._o that_o sleep_n require_v also_o a_o rest_n of_o spirit_n or_o the_o sensitive_a soul_n whereas_o relaxation_n by_o pleasure_n be_v consistent_a with_o motion_n of_o the_o spirit_n either_o by_o outward_a action_n or_o internal_a motion_n thereof_o by_o some_o inward_a cause_n hence_o it_o be_v first_o that_o we_o can_v labour_v travel_v dance_n etc._n etc._n and_o enjoy_v pleasure_n and_o its_o relaxation_n volantary_a motion_n which_o require_v only_o a_o particular_a contraction_n of_o some_o part_n by_o the_o dictate_v of_o the_o will_n or_o appetite_n be_v consistent_a with_o the_o general_a relaxation_n by_o reason_n of_o the_o prerogative_n of_o the_o will._n thus_o do_v we_o move_v though_o more_o relax_v or_o when_o most_o merry_a and_o please_v with_o wine_n nay_o some_o will_v walk_v in_o their_o sleep_n when_o extreme_o intâ—t_v upon_o a_o thing_n as_o when_o awake_a which_o show_v the_o roll_a power_n of_o intentive_a contraction_n that_o may_v be_v exercise_v with_o relaxation_n and_o other_o contraction_n as_o the_o will_n itself_o may_v or_o intentive_a appetite_n second_o that_o pain_n be_v often_o take_v away_o by_o opium_n by_o the_o diversion_n and_o relaxation_n cause_v by_o pleasure_n and_o its_o inconsistence_n with_o pain_n without_o sleep_n which_o require_v the_o aforesaid_a rest_n that_o bare_a relaxation_n as_o such_o do_v not_o include_v though_o relaxation_n suffice_v to_o take_v away_o pain_n three_o that_o opium_n do_v by_o its_o heat_n active_a particle_n etc._n etc._n hinder_v some_o person_n to_o sleep_n yet_o have_v you_o in_o both_o these_o last_o case_n all_o other_o effect_n of_o opium_n as_o pleasure_n indolence_n relaxation_n etc._n etc._n which_o show_v how_o far_o sleep_v be_v from_o be_v a_o constant_a and_o the_o most_o genuine_a effect_n of_o opium_n as_o be_v general_o imagine_v however_o we_o must_v allow_v it_o as_o have_v be_v show_v to_o be_v a_o mighty_a disposer_n of_o we_o towards_o sleep_n because_o of_o the_o relaxation_n that_o it_o cause_n which_o be_v the_o main_a requisite_a of_o sleep_n ii_o that_o pleasure_n do_v without_o nutritive_a refection_n by_o the_o complacency_n it_o cause_v in_o the_o sensitive_a soul_n produce_v comfort_n satisfaction_n composure_n elevation_n of_o the_o spirit_n euphory_n etc._n etc._n of_o which_o sleep_n be_v either_o not_o at_o all_o capable_a or_o but_o in_o a_o low_a degree_n proportionable_a to_o the_o sensation_n that_o it_o have_v which_o be_v but_o little_a however_o a_o pleasure_n that_o remain_v within_o we_o even_o in_o our_o sleep_n as_o that_o of_o opium_n may_v well_o cause_v pleasant_a dream_n etc._n etc._n the_o reader_n may_v observe_v that_o in_o all_o place_n where_o i_o mention_v that_o relaxation_n cause_v the_o open_n of_o the_o pore_n that_o i_o speak_v only_o of_o perspiration_n as_o the_o effect_n thereof_o without_o mention_v sweat_n 1._o because_o perspiration_n be_v the_o only_a constant_a and_o infallible_a effect_n thereof_o by_o reason_n that_o the_o levity_n of_o the_o fume_n cause_v they_o as_o certain_o to_o pass_v at_o the_o pore_n when_o open_a as_o smoke_n pass_v up_o at_o a_o open_a chimney_n 2._o because_o sweat_n be_v a_o uncertain_a effect_n thereof_o for_o it_o require_v that_o the_o body_n be_v well_o fill_v with_o moisture_n though_o there_o be_v a_o relaxation_n or_o open_v of_o the_o pore_n as_o hypocrates_n very_o right_o intimate_v in_o that_o aphorism_n of_o his_o that_o i_o cite_v in_o the_o last_o chapter_n 1._o because_o sweat_n have_v not_o that_o levity_n that_o the_o fume_n have_v to_o cause_v it_o ready_o to_o move_v as_o soon_o as_o the_o pore_n be_v open_a 2._o because_o relaxation_n be_v more_o apt_a to_o receive_v detain_v and_o suspend_v humour_n 3._o because_o the_o protrusive_a motion_n of_o the_o heart_n be_v weak_a in_o all_o relaxation_n and_o all_o see_v how_o much_o its_o vigorous_a protrusion_n contribute_v to_o sweat_v upon_o action_n 4._o because_o a_o heartful_a of_o blood_n do_v not_o make_v such_o a_o push_v forward_o when_o the_o artery_n be_v widen_v by_o relaxation_n 5._o sweat_n have_v more_o of_o continuity_n consistence_n and_o viscidity_n can_v flow_v out_o so_o ready_o at_o the_o pore_n as_o a_o mere_a vapour_n however_o if_o the_o body_n be_v full_a of_o moisture_n and_o the_o pore_n open_a there_o be_v a_o natural_a course_n that_o way_n and_o the_o heart_n continual_o protrude_a it_o far_o and_o far_o a_o sweat_n follow_v and_o that_o whether_o they_o sleep_v or_o not_o 3._o because_o sweat_v as_o be_v in_o some_o sort_n intimate_v be_v sometime_o cause_v by_o the_o strong_a protrusion_n of_o the_o heart_n as_o in_o motion_n etc._n etc._n and_o upon_o that_o account_n come_v more_o under_o the_o title_n of_o flux_n cause_v by_o contraction_n than_o relaxation_n of_o which_o perspiration_n be_v a_o constant_a effect_n 4._o because_o sweat_n be_v sometime_o cause_v by_o another_o sort_n of_o contraction_n viz._n the_o compression_n of_o the_o whole_a body_n by_o a_o violent_a defensive_a contraction_n as_o in_o great_a terror_n agony_n and_o the_o like_a cause_v thereby_o as_o be_v show_v by_o the_o comparison_n of_o a_o wet_a sheet_n wring_v who_o out_o side_n be_v cold_a a_o cold_a sweat_n which_o that_o of_o alum_n or_o vitriol_n cause_v a_o exudation_n of_o the_o spital_n into_o the_o mouth_n by_o constr_v the_o part_n do_v illustrate_v very_o plain_o therefore_o you_o see_v i_o have_v just_a cause_n not_o to_o mention_v sweat_n as_o a_o certain_a and_o proper_a effect_n of_o relaxation_n without_o good_a distinction_n first_o make_v though_o unwary_a author_n that_o talk_v any_o thing_n one_o after_o another_o not_o know_v what_o they_o say_v make_v it_o their_o common_a say_n that_o sleep_n and_o opium_n stop_v all_o flux_n but_o sweat_n whereas_o they_o shall_v have_v rather_o say_v but_o perspiration_n for_o opium_n and_o sleep_n also_o will_v sometime_o hinder_v sweat_n viz._n that_o from_o pain_n terror_n etc._n etc._n and_o that_o as_o happen_v just_a upon_o awake_v by_o the_o strong_a systole_n of_o the_o heart_n and_o contraction_n of_o the_o whole_a body_n and_o that_o also_o upon_o motion_n unless_o the_o body_n be_v as_o be_v say_v full_a of_o humour_n or_o moisture_n therefore_o it_o be_v a_o vulgar_a error_n to_o say_v sweat_n instead_o of_o perspiration_n in_o the_o case_n aforesaid_a you_o may_v remember_v that_o in_o the_o beginning_n of_o this_o chapter_n i_o conclude_v that_o a_o sal-volatile-oleosum_a such_o as_o semen_n humanum_fw-la wherein_o the_o oily_a and_o volatile_a part_n be_v strict_o combine_v and_o the_o volatile_a somewhat_o more_o active_a or_o acrimonious_a than_o that_o in_o our_o membrane_n in_o general_a must_v be_v most_o please_v to_o the_o membrane_n by_o a_o fine_a titillation_n etc._n etc._n therefore_o if_o opium_n shall_v prove_v to_o be_v such_o we_o need_v not_o wonder_v at_o its_o titillate_v to_o venery_n nor_o indeed_o its_o cause_v a_o high_a sense_n of_o pleasure_n upon_o any_o membrane_n they_o be_v all_o of_o the_o same_o nature_n but_o especial_o upon_o the_o most_o exquisite_o dispose_v membrane_n of_o the_o stomach_n and_o the_o venereal_a part_n nor_o consequent_o its_o cause_v all_o the_o aforementioned_a effect_n of_o intense_a pleasure_n as_o comfort_n satisfaction_n ovation_n etc._n etc._n of_o the_o sensitive_a soul_n or_o spirit_n and_o relaxation_n of_o all_o the_o sensile_a part_n which_o will_v easy_o solve_v all_o the_o phenomenas_n of_o opium_n however_o numerous_a mysterious_a and_o seem_o contradictory_n as_o you_o will_v find_v let_v we_o therefore_o now_o see_v whether_o opium_n be_v such_o a_o sal-volatile-oleosum_a wherein_o the_o volatile_a particle_n be_v somewhat_o more_o active_a or_o acrimonious_a than_o we_o and_o the_o oily_a and_o volatile_a part_n strict_o combine_v if_o so_o the_o business_n be_v do_v the_o nail_n be_v hit_v on_o the_o head_n and_o i_o may_v say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d chap._n xv._o show_v what_o be_v the_o principle_n of_o opium_n and_o which_o cause_n the_o good_a and_o bad_a effect_n thereof_o have_v try_v if_o not_o tire_v your_o patience_n and_o premise_v what_o i_o think_v necessary_a in_o the_o forego_n chapter_n i_o now_o reassume_v the_o thread_n of_o my_o discourse_n as_o for_o the_o passive_a principle_n of_o opium_n which_o do_v or_o signify_v little_a or_o nothing_o
part_n by_o its_o relax_v the_o pore_n of_o the_o kidney_n and_o render_v the_o humour_n more_o penetrate_v in_o some_o measure_n by_o the_o volatile_a salt_n 20._o it_o cause_v a_o nausea_n by_o its_o rosin_n stick_v to_o and_o teaze_v the_o sensile_a coat_n of_o the_o stomach_n the_o reason_n why_o it_o be_v general_o so_o long_o before_o it_o cause_v a_o nausea_n or_o vomit_v be_v that_o its_o pleasure_n do_v at_o first_o prevent_v it_o till_o at_o last_o the_o stick_a rosin_n urge_v it_o by_o its_o long_a stay_n and_o vexatious_a adherence_n 21._o it_o cause_v swimmings_n in_o the_o head_n by_o consent_n when_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o you_o find_v upon_o nauseas_fw-la before_o vomit_v or_o when_o any_o thing_n do_v much_o offend_v the_o stomach_n as_o much_o drink_n or_o wine_n which_o when_o they_o have_v vomit_v those_o swimming_n cease_v 22._o it_o cause_v watch_v in_o some_o person_n who_o be_v of_o very_o movable_a spirit_n by_o actuate_a and_o stir_v their_o spirit_n by_o its_o active_a volatile_a salt_n though_o it_o do_v at_o the_o same_o time_n please_v the_o membrane_n and_o consequent_o relax_v the_o sensile_a part_n and_o thereby_o cause_n indolence_n the_o effect_n of_o relaxation_n which_o it_o also_o do_v when_o people_n keep_v themselves_o from_o sleep_n by_o voluntary_a motion_n and_o therefore_o take_v away_o pain_n even_o when_o man_n travel_v etc._n etc._n beside_o there_o be_v some_o sort_n of_o person_n that_o upon_o joy_n good_a news_n pleasure_n or_o the_o like_a be_v too_o much_o elevate_v or_o have_v a_o restless_a ovation_n of_o the_o spirit_n which_o will_v not_o suffer_v they_o to_o sleep_n though_o they_o be_v in_o a_o pleasant_a condition_n all_o the_o time_n this_o may_v be_v the_o case_n of_o some_o that_o can_v sleep_v after_o opium_n though_o they_o be_v all_o the_o time_n as_o they_o call_v it_o in_o a_o heavenly_a condition_n for_o as_o i_o have_v say_v a_o quietness_n of_o the_o spirit_n be_v requisite_a to_o cause_v sleep_n as_o well_o as_o relaxation_n but_o relaxation_n alone_o and_o thereby_o expansion_n of_o the_o spirit_n so_o that_o they_o can_v carry_v impression_n smart_o be_v sufficient_a to_o cause_v indolence_n and_o the_o pleasure_n to_o cause_v a_o heavenly_a or_o very_o pleasant_a condition_n sanctor_n stat._n med._n sect._n 7._o aph._n 28._o say_v that_o laetitia_n perseverans_fw-la per_fw-la multos_fw-la dies_fw-la somnum_fw-la impedit_fw-la persevere_v pleasure_n may_v do_v the_o same_o by_o like_a reason_n that_o be_v too_o much_o 〈◊〉_d or_o ovation_n of_o the_o spirit_n sometime_o too_o large_a a_o do_v cause_n watch_v by_o over-actuating_a and_o exciting_a the_o spirit_n medicum_fw-la vini_fw-la generosi_fw-la &_o allium_fw-la say_v sanctorius_n conciliant_fw-la somnum_fw-la &_o perspirationem_fw-la si_fw-la vero_fw-la plus_fw-la justo_fw-la sumantur_fw-la utrumque_fw-la prohibent_fw-la perspirabile_fw-la tamen_fw-la in_o sudorem_fw-la convertunt_fw-la that_o be_v a_o little_a generous_a wine_n and_o garlic_n will_v cause_v sleep_n and_o perspiration_n but_o too_o much_o hinder_v both_o yet_o they_o convert_v the_o perspirable_a matter_n to_o a_o sweat_n which_o wine_n and_o garlick_n have_v the_o nature_n of_o opiate_n and_o the_o reason_n why_o they_o sweat_v be_v the_o quantity_n of_o the_o wine_n afford_v more_o moisture_n hypocrates_n say_v 23._o a_o dubious_a state_n between_o sleep_v and_o wake_v be_v cause_v when_o the_o relaxation_n upon_o the_o pleasure_n of_o opium_n incline_v to_o sleep_v but_o the_o irreâ—uiete_a ovation_n of_o the_o spirit_n by_o the_o pleasure_n and_o titillation_n will_v hardly_o suffer_v it_o yet_o high_o please_v and_o put_v they_o in_o a_o sweet_a agreeable_a condition_n chap._n xix_o the_o explication_n of_o the_o rare_a effect_n of_o opium_n in_o a_o moderate_a do_v 1._o it_o cause_v temporary_a pulse_n of_o the_o 〈◊〉_d and_o sometime_o of_o other_o part_n by_o its_o over_o relax_v the_o part_n and_o cause_v thereby_o a_o expansion_n of_o the_o elastic_a spirit_n which_o as_o be_v demonstrate_v weaken_v their_o motion_n 2._o falter_v of_o the_o tongue_n do_v as_o in_o relaxation_n by_o drunkenness_n proceed_v from_o the_o same_o cause_n 3._o looseness_n of_o the_o low_a jaw_n as_o you_o see_v in_o the_o drowsy_a and_o drunken_a people_n be_v from_o the_o same_o relaxation_n 4._o it_o sometime_o prevent_v sweat_n by_o cause_v a_o very_a liberal_a perspiration_n as_o be_v show_v for_o as_o sanctorius_n say_v who_o shall_v know_v it_o much_o insensible_a perspiration_n and_o sweat_n can_v consist_v especial_o in_o a_o temperate_a person_n who_o eat_v and_o drink_v moderate_o therefore_o if_o you_o keep_v a_o person_n that_o sweat_v much_o at_o night_n in_o a_o free_a perspiration_n all_o day_n by_o the_o help_n of_o a_o opiate_n you_o will_v much_o lessen_v or_o total_o prevent_v the_o sweat_n at_o night_n as_o in_o consumptive_a person_n etc._n etc._n 5._o it_o cause_v abortion_n by_o relax_v the_o neck_n of_o the_o womb_n which_o also_o the_o pleasure_n of_o coition_n sometime_o do_v for_o the_o like_a reason_n and_o will_v be_v much_o more_o apt_a to_o cause_v it_o if_o it_o continue_v long_o as_o that_o of_o opium_n do_v note_v the_o inconvenience_n of_o coition_n after_o impregnation_n this_o be_v the_o great_a cause_n that_o whore_n be_v not_o apt_a to_o bear_v child_n because_o frequency_n of_o pleasure_n do_v over-relax_a the_o collum_n 〈◊〉_d 6._o it_o prevent_v abortion_n when_o fear_n terror_n or_o any_o contract_a cause_n as_o grief_n grievous_a passion_n or_o sensation_n do_v threaten_v it_o by_o its_o take_n off_o the_o contraction_n and_o grievance_n that_o cause_v it_o 7_o intumescence_n of_o the_o lip_n be_v from_o their_o relaxation_n admit_v the_o blood_n and_o humour_n into_o they_o in_o a_o plentiful_a manner_n beside_o that_o their_o laxity_n and_o the_o inadvertency_n occasion_v by_o the_o divert_v pleasure_n or_o drowsiness_n that_o follow_v let_v the_o low_a lip_n hang_v down_o careless_o as_o be_v usual_a in_o such_o case_n may_v by_o expose_v much_o more_o of_o that_o lip_n which_o be_v most_o concern_v in_o this_o effect_n make_v it_o seem_v large_a as_o a_o hang_a lip_n do_v 8._o it_o may_v cure_v a_o dropsy_n as_o dr._n wâ—llis_n do_v instance_n 1._o by_o cause_v a_o free_a perspiration_n which_o be_v much_o want_v in_o those_o case_n 2._o by_o relax_v the_o pore_n and_o make_v way_n for_o the_o humour_n to_o 〈◊〉_d 3._o by_o cause_v much_o urine_n as_o cantharides_n millepedes_n &c_n &c_n do_v upon_o the_o account_n of_o their_o volatile-salt_n with_o which_o opium_n abound_v 9_o it_o cure_v stupor_n that_o proceed_v from_o contraction_n as_o by_o cold_a etc._n etc._n by_o relax_v all_o part_n 10._o it_o cause_v anxiety_n and_o distress_n by_o the_o rosin_n stick_v and_o teaze_v the_o stomach_n 11._o vomit_n and_o hiccough_n proceed_v from_o the_o same_o cause_n 12._o convulsion_n be_v cause_v by_o the_o same_o rosin_n while_o it_o continual_o urge_v the_o stomach_n to_o grievous_a vomit_n which_o at_o last_o draw_v other_o part_n as_o the_o stomach_n usual_o do_v when_o under_o great_a grievance_n into_o violent_a contraction_n or_o convulsion_n by_o consent_n to_o endeavour_v its_o assistance_n because_o the_o defensive_a contraction_n grow_v very_o high_a by_o the_o almost_o intolerable_a and_o tedious_a grievance_n at_o stomach_n cause_v a_o mighty_a compression_n of_o the_o springy_a animal_n spirit_n by_o which_o mean_v they_o grow_v very_o forcible_a irrequiete_a and_o violent_o springy_a under_o the_o urgency_n of_o a_o enormous_a compressure_n which_o cause_v such_o convulsive_a motion_n note_v that_o such_o a_o violent_a compression_n of_o the_o animal_n spirit_n into_o a_o great_a springiness_n be_v the_o cause_n of_o the_o strength_n of_o convulsive_a motion_n so_o that_o sometime_o a_o strong_a man_n can_v hardly_o hold_v a_o child_n limb_n in_o such_o case_n 13._o syncopes_fw-la leipothymy_n and_o faint_n follow_v when_o the_o sensitive_a soul_n be_v quite_o tire_v and_o overbear_v by_o the_o fatigue_n of_o such_o distress_n vomit_n and_o defensive_a contraction_n to_o reject_v and_o excuss_v the_o say_v adhere_v and_o teaze_v rosin_n yield_v itself_o to_o rest_n and_o let_v we_o go_v the_o reign_v of_o contraction_n as_o be_v fruitless_a and_o no_o long_o endurable_a whereupon_o all_o the_o sensile_a part_n be_v relax_v in_o the_o high_a degree_n they_o thereby_o grow_v unfit_a for_o sensation_n and_o the_o animal_n spirit_n expand_v as_o far_o as_o the_o atmospherical_a compressure_n permit_v they_o so_o that_o they_o grow_v incapable_a to_o convey_v impression_n by_o which_o mean_v sense_n fail_v and_o motion_n also_o for_o the_o same_o reason_n because_o the_o animal_n spirit_n loose_v their_o springy_a endeavour_n for_o want_n of_o a_o sufficient_a compression_n to_o render_v they_o flippant_a for_o the_o purpose_n which_o be_v the_o cause_n as_o in_o sleep_n that_o sense_n
with_o bean_n trefoil_n some_o with_o centaury_n other_o with_o gentian_n etc._n etc._n and_o the_o famous_a dr._n lower_n practice_n run_v almost_o altogether_o upon_o bitter_a thing_n which_o do_v he_o great_a service_n in_o his_o tincture_n of_o steel_n as_o he_o call_v it_o that_o he_o often_o make_v in_o distil_v water_n that_o can_v take_v little_a or_o nothing_o to_o purpose_n of_o the_o tincture_n of_o steel_n whether_o out_o of_o ignorance_n or_o design_n i_o will_v not_o though_o i_o may_v determine_v which_o show_v that_o it_o be_v the_o bitter_a thing_n that_o do_v the_o good_a and_o make_v it_o as_o a_o panacea_fw-la and_o not_o the_o steel_n however_o certain_a it_o be_v that_o promote_a the_o dissolution_n of_o meat_n at_o stomach_n which_o the_o bitter_a salia-volatalia-oleosa_a do_v be_v a_o great_a foundation_n for_o cure_n and_o no_o doubt_n our_o sal-volatile-oleosum_a do_v by_o its_o incide_v divide_v and_o resolve_v quality_n contribute_v very_o much_o to_o a_o due_a solution_n thereof_o at_o stomach_n by_o connaturalness_n as_o all_o menstruum_n do_v especial_o if_o it_o be_v flesh_n which_o we_o use_v most_o and_o require_v most_o help_n to_o be_v resolve_v which_o may_v very_o well_o be_v though_o it_o lessen_v appetite_n by_o please_a sensation_n for_o as_o be_v show_v it_o be_v quite_o another_o thing_n to_o cause_n appetite_n or_o a_o grievous_a sensation_n and_o resolution_n or_o digestion_n of_o the_o meat_n at_o stomach_n for_o wine_n help_v digestion_n yet_o by_o the_o please_a sensation_n that_o it_o cause_n at_o stomach_n it_o cure_v a_o canine_a appetite_n and_o at_o any_o time_n if_o you_o will_v observe_v it_o take_v off_o the_o eagerness_n of_o appetise_n for_o the_o present_a you_o can_v better_o stay_v without_o meat_n after_o a_o whet_v before_o dinner_n than_o you_o can_v without_o it_o so_o that_o the_o wine_n answer_v that_o of_o a_o whet_v as_o to_o digestion_n though_o not_o to_o appetite_n or_o hunger_n which_o be_v a_o grievous_a sensation_n that_o wine_n must_v rather_o cure_v than_o cause_n it_o be_v true_a that_o wine_n or_o opium_n may_v by_o cause_v a_o sense_n of_o pleasure_n at_o stomach_n cause_n some_o stay_n of_o the_o meat_n at_o stomach_n but_o it_o do_v not_o thence_o follow_v but_o the_o digestion_n may_v be_v the_o true_a because_o more_o gentle_a and_o gradual_a as_o it_o may_v and_o do_v happen_v in_o sleep_n when_o thing_n that_o be_v not_o very_o hard_a of_o digestion_n be_v eat_v which_o be_v not_o good_a at_o any_o time_n you_o may_v remember_v how_o blister_n to_o which_o opium_n be_v near_o of_o kind_a as_o have_v be_v show_v do_v quick_o by_o their_o resolve_v nature_n turn_v the_o cuticle_n as_o if_o digest_v into_o a_o sort_n of_o jelly_n what_o a_o mighty_a help_n will_v such_o a_o degree_n of_o resolution_n be_v to_o the_o digestion_n at_o stomach_n when_o it_o be_v by_o that_o mean_n like_o the_o skin_n of_o a_o well_o boil_a cow-heel_n half_o turn_v to_o a_o jelly_n and_o from_o a_o thing_n that_o be_v very_o hard_a of_o digestion_n to_o be_v very_o easy_a as_o be_v also_o a_o boar_n skin_n in_o brawn_n by_o reason_n of_o the_o prior_n resolution_n in_o the_o boil_n if_o as_o sanctorius_n say_v insensible_a perspiration_n hinder_v be_v the_o cause_n of_o most_o disease_n what_o be_v more_o proper_a to_o prevent_v or_o cure_v they_o than_o this_o sal-volatile-oleosum_a which_o cause_v perspiration_n above_o all_o thing_n i_o have_v be_v late_o inform_v that_o in_o some_o part_n of_o the_o most_o eastern_a country_n they_o use_v opium_n as_o a_o general_a medicament_n or_o panacea_fw-la dr._n willis_n and_o silvius_n say_v it_o hinder_v the_o coagulation_n of_o the_o blood_n how_o many_o chronical_a disease_n may_v it_o then_o prevent_v or_o cure_v that_o be_v the_o great_a effect_n of_o the_o alcahest_n and_o that_o be_v it_o that_o main_o qualify_v a_o medicament_n for_o a_o panacea_fw-la as_o courvee_a assert_n and_o all_o ingenious_a man_n allow_v wedelius_n say_v that_o it_o happy_o restore_v the_o tone_n of_o the_o blood_n what_o be_v then_o want_v to_o the_o preservation_n of_o health_n paracelsus_n say_v that_o tam_fw-la homini_fw-la quam_fw-la morbo_fw-la somnum_fw-la conciliat_fw-la that_o be_v that_o it_o put_v the_o disease_n asleep_o as_o well_o as_o the_o man._n ☞_o platerius_n cure_v the_o gout_n with_o it_o safe_o quick_o and_o pleasant_o and_o i_o know_v one_o that_o can_v do_v it_o especial_o if_o it_o be_v at_o the_o first_o come_v of_o the_o fit_n willis_n give_v a_o instance_n of_o one_o perfect_o cure_v of_o a_o dropsy_n and_o pocky_a pain_n by_o the_o use_n of_o laudanum_n ☞_o horstius_fw-la perfect_o cure_v a_o hypochondriacal_a person_n that_o be_v trouble_v with_o stupidity_n watch_n loss_n of_o appetite_n tremble_v and_o direful_a epileptical_a convulsion_n and_o past_o all_o hope_n by_o the_o use_n of_o opiate_n i_o myself_o have_v often_o see_v defluxion_n and_o catarrh_n cure_v by_o the_o use_n of_o opiate_n and_o one_o of_o a_o inveterate_a ill_a habit_n of_o body_n of_o many_o year_n stand_v wedelius_n say_v that_o it_o resolve_v the_o grumescence_n of_o the_o blood_n alter_v and_o dissipate_v the_o tenuious_a part_n of_o it_o temper_n the_o acrimonious_a etc._n etc._n the_o ancient_n use_v it_o against_o ague_n with_o great_a success_n you_o may_v to_o confirm_v this_o matter_n far_a observe_v that_o among_o the_o constant_a and_o frequent_a effect_n of_o opium_n there_o be_v no_o bad_a one_o unless_o there_o be_v 2_o or_o 3_o pure_o upon_o the_o account_n of_o its_o rosin_n as_o have_v be_v show_v therefore_o when_o it_o be_v separate_v from_o it_o there_o be_v no_o cause_n to_o fear_v the_o use_n of_o the_o sal-volatile-oleosum_a unless_o it_o be_v as_o in_o the_o case_n of_o wine_n when_o it_o be_v take_v in_o a_o excessive_a do_v or_o use_v too_o long_o in_o a_o lavish_a intemperate_a manner_n so_o that_o when_o i_o have_v show_v how_o due_o to_o prepare_v it_o and_o the_o moderate_a and_o safe_a dose_n thereof_o it_o may_v be_v use_v altogether_o as_o safe_o as_o wine_n in_o a_o proportionable_a do_v for_o what_o harm_n can_v there_o be_v in_o moderate_o please_v the_o membrane_n particular_o at_o stomach_n which_o all_o the_o best_a thing_n we_o use_v as_o wine_n cordial_n meat_n and_o drink_v do_v which_o be_v therefore_o all_o opiate_n in_o some_o degree_n thereby_o assure_v we_o of_o their_o goodness_n and_o agreeableness_n to_o our_o body_n though_o they_o do_v it_o not_o in_o so_o high_a a_o dgree_n as_o our_o sal-volatile-oleosum_a do_v which_o be_v the_o more_o authentic_a certificate_n of_o its_o excellency_n though_o it_o be_v to_o be_v still_o confess_v that_o excess_n of_o the_o best_a thing_n as_o joy_n comfort_n pleasure_n wine_n cordial_n etc._n etc._n have_v and_o may_v do_v mischief_n but_o what_o need_v excess_n therein_o any_o more_o than_o in_o wine_n meat_n cordial_n etc._n etc._n which_o then_o like_v it_o be_v all_o inconvenient_a and_o injurious_a to_o the_o body_n all_o this_o i_o have_v say_v to_o administer_v cause_n to_o improve_v the_o practice_n of_o physic_n by_o the_o use_n of_o this_o panacea_fw-la now_o that_o it_o be_v know_v by_o introduce_v its_o noble_a use_n as_o a_o alterative_a to_o cure_n as_o well_o as_o former_o to_o palliate_v disease_n it_o be_v a_o far_o more_o beneficial_a thing_n to_o cure_v than_o palliate_v remember_v how_o the_o cortex_fw-la mercury_n antimony_n and_o other_o the_o most_o effectual_a and_o glorious_a medicament_n have_v be_v traduce_v and_o scandalize_v by_o the_o ignorant_a imagination_n of_o the_o unlearned_a who_o have_v no_o true_a knowledge_n of_o the_o virtue_n of_o thing_n whole_o depend_v upon_o fear_n and_o jealousy_n to_o guard_v they_o from_o their_o imagine_a ill_a effect_n which_o general_o speak_v only_o the_o same_o ignorance_n fear_n and_o jealousy_n give_v a_o fantastical_a be_v to_o it_o remain_v that_o i_o in_o the_o next_o place_n show_v you_o 1._o the_o true_a preparation_n of_o this_o panacea_fw-la or_o sal-volatile-oleosum_a 2._o other_o preparation_n of_o opium_n that_o be_v next_o it_o in_o safety_n and_o good_a effect_n and_o why_o they_o be_v so_o 3._o the_o moderate_a and_o true_o safe_a dose_v of_o they_o all_o there_o be_v no_o danger_n in_o well_o prepare_v opium_n but_o from_o excess_n in_o the_o use_v thereof_o chap._n xxv_o of_o the_o preparation_n of_o the_o panacea_fw-la or_o true_a sal-volatile-oleosum_a of_o opium_n see_v that_o the_o sal-volatile-oleosum_a of_o opium_n must_v be_v such_o a_o effectual_a generous_a and_o general_a medicament_n that_o be_v both_o cordial_a and_o alterative_a in_o so_o transcendent_a a_o manner_n it_o well_o deserve_v a_o careful_a and_o curious_a preparation_n therefore_o i_o will_v be_v very_o particular_a therein_o to_o that_o end_n 1._o it_o must_v be_v separate_v from_o all_o the_o
leave_v that_o to_o other_o physician_n to_o please_v themselves_o or_o patient_n by_o add_v ambergrise_n musk_n saffron_n oil_n of_o cinnamon_n or_o other_o chemical_a oil_n sugar_n or_o the_o like_a according_a to_o their_o intent_n i_o have_v observe_v that_o as_o reason_n tell_v we_o its_o smell_n be_v best_a palliate_v by_o other_o rank_n smell_v as_o that_o of_o onion_n garlic_n asa-foetida_a etc._n etc._n and_o its_o bitter_a taste_n with_o bitter_a thing_n as_o gentian_n centaury_n etc._n etc._n therefore_o when_o person_n that_o know_v its_o smell_n and_o taste_n be_v aver_v to_o take_v it_o if_o the_o other_o more_o acceptable_a thing_n will_v not_o suffice_v for_o that_o purpose_n use_v some_o of_o these_o you_o may_v when_o you_o be_v in_o haste_n infuse_v half_o a_o dozen_o slice_n of_o gentian-root_n and_o one_o slice_v of_o a_o onion_n or_o a_o bruise_a clove_n of_o garlic_n or_o both_o in_o a_o glass_n of_o wine_n for_o one_o hour_n for_o a_o vehicle_n in_o that_o case_n it_o be_v better_o to_o infuse_v they_o long_o if_o you_o have_v time_n but_o you_o will_v find_v that_o the_o liquid_a panacea_fw-la have_v not_o such_o a_o mighty_a rank_a taste_n or_o smell_v but_o that_o it_o be_v easy_o palliate_v by_o such_o mean_n if_o the_o opium_n have_v no_o empyreum_fw-la the_o solid_a panacea_fw-la may_v be_v also_o palliate_v by_o the_o same_o thing_n convenient_o mix_v therewith_o i_o know_v there_o be_v other_o way_n and_o mean_n to_o separate_v the_o rosin_n etc._n etc._n as_o extract_v a_o tincture_n of_o opium_n in_o spirit_n of_o wine_n and_o afterward_o precipitate_v the_o rosin_n with_o distil_a rain-water_n but_o this_o be_v attend_v with_o more_o trouble_n and_o many_o inconvenience_n that_o be_v avoid_v by_o the_o cold_a distil_a rain-water_n for_o 1._o you_o know_v not_o how_o the_o spirit_n of_o wine_n may_v as_o be_v say_v alter_v it_o 2._o this_o be_v go_v round_o the_o bush_n and_o compound_v two_o menstruum_n together_o whereas_o the_o simple_a water_n use_v alone_o be_v much_o better_a 3._o you_o can_v thus_o separate_v the_o resinous_a particle_n so_o perfect_o by_o reason_n that_o the_o spirit_n of_o wine_n must_v retain_v some_o of_o they_o and_o if_o you_o add_v more_o and_o more_o water_n in_o the_o precipitation_n the_o tincture_n become_v too_o much_o dilute_v and_o very_o weak_a how_o much_o better_a be_v it_o to_o use_v a_o menstruum_fw-la that_o never_o take_v up_o any_o rosin_n and_o consequent_o need_v no_o such_o separation_n and_o labour_n of_o precipitation_n it_o be_v better_a not_o to_o admit_v a_o enemy_n to_o one_o country_n than_o afterward_o to_o endeavour_v his_o expulsion_n for_o he_o will_v at_o best_a leave_n some_o mark_n of_o his_o hostility_n behind_o he_o as_o the_o rosin_n will_v in_o the_o spirit_n of_o wine_n the_o like_a inconvenience_n there_o will_v be_v in_o separate_v it_o by_o the_o way_n of_o distillation_n as_o 1._o the_o alter_n of_o it_o by_o the_o tyranny_n of_o fire_n 2._o the_o loss_n of_o it_o by_o evaporation_n 3._o the_o addition_n of_o the_o particle_n of_o fire_n thereto_o 4._o the_o never_o separate_a it_o so_o well_o that_o way_n 5._o the_o disunit_a of_o the_o oil_n and_o volatile_a salt_n in_o some_o measure_n but_o what_o experience_n may_v hereafter_o teach_v man_n i_o will_v not_o determine_v neither_o can_v 1_n but_o this_o i_o can_v that_o as_o it_o be_v even_o miraculous_a that_o people_n shall_v never_o mind_v the_o cause_n they_o daily_o feel_v and_o solicitous_o seek_v for_o so_o it_o be_v as_o strange_a that_o they_o can_v not_o hit_v upon_o the_o plain_a use_n of_o water_n so_o very_o common_a in_o all_o hand_n for_o a_o menstruum_fw-la either_o by_o chance_n or_o consideration_n in_o all_o the_o eastern_a part_n of_o the_o world_n where_o it_o be_v so_o universal_o take_v or_o in_o the_o inquisitive_a western_a part_n of_o the_o world_n where_o it_o have_v be_v study_v and_o consider_v by_o great_a number_n with_o the_o utmost_a diligence_n but_o they_o pass_v over_o water_n as_o despicable_a because_o common_a for_o familiarity_n breed_v contempt_n though_o its_o be_v make_v the_o drink_n of_o all_o live_a creature_n by_o the_o omniscient_n shall_v commend_v it_o above_o all_o thing_n do_v like_o those_o that_o regardless_o pass_v over_o a_o jewel_n or_o treasure_n and_o have_v once_o leave_v it_o behind_o they_o proceed_v far_o and_o far_o from_o it_o the_o great_a progress_n they_o make_v conclude_v that_o it_o be_v not_o to_o be_v find_v the_o way_n they_o pass_v not_o because_o it_o be_v not_o there_o but_o because_o they_o can_v not_o see_v it_o as_o for_o the_o keep_n of_o the_o liquid_a panacea_fw-la uncorrupted_a i_o do_v not_o find_v it_o apt_a to_o change_v however_o because_o make_v so_o easy_o by_o bare_a throw_v it_o into_o water_n it_o need_v not_o be_v keep_v long_o but_o may_v be_v make_v upon_o all_o occasion_n or_o at_o least_o one_o under_o the_o other_o as_o the_o apothecary_n spend_v it_o who_o it_o be_v not_o improbable_a may_v by_o their_o great_a ingenuity_n and_o experience_n in_o those_o matter_n find_v other_o convenient_a mean_n to_o preserve_v it_o for_o their_o purpose_n chap._n xxvi_o of_o other_o preparation_n of_o opium_n that_o be_v absolute_o or_o tolerable_o safe_a in_o a_o moderate_a do_v i._o all_z preparation_n be_v very_o safe_a in_o a_o moderate_a do_v wherein_o the_o resinous_a part_n of_o the_o opium_n be_v whole_o separate_v from_o it_o such_o be_v all_o extract_v make_v in_o aqueous_a menstruum_n or_o any_o other_o that_o imbibe_v none_o of_o the_o resinous_a part_n of_o opium_n as_o the_o preparation_n that_o wedâ—lius_n have_v in_o his_o opiologia_fw-la l._n 1._o sect._n 2._o cap._n 5._o p._n 65._o which_o be_v extract_v out_o of_o phlegm_n of_o vinegar_n that_o remain_v after_o the_o preparation_n of_o arcanum_n tartari_fw-la so_o laudanum_n liquidum_fw-la cydoniatum_n and_o langelott_n laudanum_n if_o the_o resinous_a part_n be_v due_o separate_v be_v very_o safe_a and_o commendable_a for_o the_o like_a reason_n as_o be_v also_o le_fw-fr mort's_n extract_n out_o of_o rain-water_n diacodium_fw-la etc._n etc._n ii_o all_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n though_o not_o separate_v from_o it_o be_v so_o alter_v order_v divide_v etc._n etc._n as_o not_o to_o stick_v to_o the_o stomach_n and_o render_v digestible_a and_o passable_a out_o of_o it_o without_o offence_n may_v be_v safe_o use_v of_o this_o kind_n there_o be_v or_o may_v be_v two_o sort_n first_o such_o wherein_o the_o nature_n of_o the_o rosin_n be_v alter_v in_o some_o degree_n at_o least_o second_o such_o wherein_o though_o the_o nature_n of_o the_o rosin_n be_v not_o destroy_v yet_o be_v it_o so_o order_v divide_a etc._n etc._n as_o not_o to_o stick_v to_o the_o stomach_n but_o render_v digestible_a and_o passable_a without_o offence_n of_o the_o first_o sort_n be_v 1._o such_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n be_v quite_o alter_v in_o its_o form_n and_o nature_n by_o chemistry_n or_o artificial_a torture_n of_o fire_n which_o because_o hardly_o to_o be_v do_v without_o much_o impair_n the_o sal-volatile-oleosum_a will_v be_v neither_o commendable_a nor_o worth_a while_n consider_v how_o easy_o without_o that_o trouble_v pain_n and_o labour_n even_o the_o rosin_n itself_o may_v be_v separate_v whole_o from_o the_o opium_n by_o aqueous_a menstruum_n 2._o such_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n be_v alter_v and_o as_o it_o be_v soapify_v by_o lixivial_a salt_n or_o soap_n which_o ready_o engage_v and_o intimate_o join_v with_o the_o small_a resinous_a particle_n of_o the_o opium_n by_o long_a and_o strong_a pound_v they_o together_o in_o a_o mortar_n or_o otherwise_o as_o in_o matthew_n or_o starkey_n pill_n bates's_fw-fr pacifick_n pill_n etc._n etc._n by_o which_o mean_v those_o resinous_a particle_n become_v in_o a_o great_a degree_n at_o least_o if_o not_o whole_o miscible_a with_o and_o so_o dissolvable_a and_o digestible_a in_o the_o liquor_n we_o drink_v and_o easy_o subduable_a by_o the_o menstruum_fw-la at_o stomach_n out_o of_o which_o it_o also_o easy_o pass_v by_o reason_n of_o the_o great_a slipperiness_n it_o acquire_v which_o also_o prevent_v its_o stick_n by_o that_o intimate_a mixture_n with_o the_o soap_n or_o lixivial_n therefore_o i_o take_v those_o pill_n of_o matthews_n and_o dr._n bates_n to_o be_v safe_a preparation_n though_o not_o to_o be_v compare_v to_o the_o panacea_fw-la wherein_o all_o danger_n and_o its_o cause_n be_v quite_o take_v away_o by_o whole_o separate_v the_o resinous_a part_n earth_n and_o filth_n of_o the_o opium_n from_o its_o sal-volatile-oleosum_a and_o doubtless_o have_v maththews_n starkey_n and_o bates_n know_v that_o the_o rosin_n of_o opium_n have_v be_v the_o cause_n of_o its_o ill_a effect_n they_o will_v never_o
have_v spend_v month_n in_o prepare_v the_o sapo_n tartareus_fw-la to_o correct_v opium_n when_o they_o may_v with_o the_o hundred_o part_n of_o the_o trouble_v and_o forty_o part_n of_o the_o time_n whole_o have_v take_v away_o the_o pernicious_a part_n by_o aqueous_a menstruum_n which_o they_o only_o pretend_v to_o correct_v by_o the_o sapo_n tartareus_fw-la though_o i_o allow_v it_o for_o the_o reason_n aforesaid_a to_o be_v a_o good_a corrector_n yet_o can_v it_o equal_v the_o total_a separation_n of_o the_o pernicious_a part_n i_o be_o of_o opinion_n upon_o my_o best_a thought_n and_o some_o experience_n that_o intimate_o mix_v and_o subdue_a opium_n with_o good_a white_a soap_n may_v for_o the_o reason_n aforesaid_a prove_v a_o good_a and_o ready_a corrector_n or_o preventer_n of_o the_o adhesion_n of_o the_o resinous_a part_n of_o opium_n to_o the_o stomach_n much_o conduce_v to_o its_o dissolution_n or_o digestion_n therein_o and_o nimble_a slip_n out_o of_o it_o and_o thereby_o prevent_v all_o the_o ill_a effect_n of_o opium_n which_o it_o cause_v by_o the_o adhesion_n and_o indigestibleness_n of_o its_o rosin_n of_o the_o second_o sort_n of_o preparation_n of_o opium_n wherein_o its_o rosin_n remain_v whole_o unaltered_a in_o its_o nature_n yet_o become_v safe_a by_o divide_v it_o etc._n etc._n this_o be_v main_o if_o not_o altogether_o do_v by_o a_o fine_a and_o through_o division_n of_o the_o resinous_a part_n of_o opium_n and_o keep_v they_o afterward_o from_o a_o coalescence_n in_o and_o adhesion_n to_o the_o stomach_n by_o which_o mean_n they_o become_v digestible_a or_o at_o least_o passable_a without_o offence_n this_o may_v be_v do_v 1._o by_o torrefaction_n till_o the_o opium_n be_v very_o friable_a and_o then_o fine_o powder_a it_o and_o mix_v it_o with_o such_o thing_n as_o be_v of_o good_a consistence_n etc._n etc._n to_o keep_v the_o part_n of_o opium_n from_o a_o coalescence_n as_o in_o venice_n treacle_n mithridate_n diascordium_n the_o philonium_n etc._n etc._n this_o be_v the_o way_n and_o method_n that_o the_o ancient_n use_v which_o cause_v galen_n to_o say_v that_o opium_n alone_o that_o be_v undivided_a and_o unmixed_a with_o other_o thing_n to_o prevent_v its_o coalescence_n etc._n etc._n be_v dangerous_a but_o mix_v with_o other_o thing_n be_v salutiferous_a which_o they_o find_v by_o experience_n not_o know_v the_o cause_n but_o attribute_v the_o safety_n thereof_o to_o something_o among_o the_o many_o ingredient_n as_o a_o corrector_n of_o the_o opium_n hence_o it_o be_v that_o they_o put_v small_a quantity_n thereof_o into_o electuary_n make_v of_o many_o and_o much_o other_o thing_n that_o keep_v the_o particle_n asunder_o which_o they_o do_v so_o common_o that_o at_o last_o all_o electuary_n be_v call_v opiate_n thus_o we_o have_v those_o composition_n above_o name_v which_o be_v safe_o use_v for_o the_o reason_n aforesaid_a not_o that_o any_o thing_n therein_o correct_v i_o know_v not_o what_o poisonous_a or_o narcotick_a quality_n in_o opium_n but_o that_o the_o other_o ingredient_n divide_v its_o rosin_n and_o afterward_o keep_v its_o particle_n from_o coalescence_n and_o adhesion_n 2._o dissolution_n of_o opium_n in_o spirit_n of_o wine_n or_o such_o sulphureous_a spirit_n which_o fine_o divide_v the_o rosin_n and_o use_v the_o bare_a tincture_n before_o the_o resinous_a particle_n be_v again_o compact_v as_o in_o extract_n etc._n etc._n may_v be_v of_o use_n if_o due_o administer_v but_o here_o a_o caution_n be_v to_o be_v use_v that_o you_o take_v it_o not_o in_o or_o drink_v any_o aqueous_a or_o phlegmatic_a liquid_a with_o it_o or_o before_o or_o after_o it_o in_o two_o or_o three_o hour_n which_o if_o you_o do_v the_o resinous_a particle_n will_v be_v precipitate_v thereby_o and_o so_o stick_v to_o the_o bottom_n tom_fw-mi of_o the_o stomach_n cause_v thereby_o the_o usual_a ill_a effect_n of_o vomit_v anxiety_n etc._n etc._n therefore_o it_o shall_v be_v give_v only_o in_o a_o spirituous_a liquid_a note_v also_o that_o if_o you_o give_v a_o solution_n thereof_o in_o any_o lixivium_n you_o take_v care_v not_o to_o dilate_v it_o by_o any_o mean_n by_o aqueous_a liquid_n in_o two_o hour_n before_o or_o after_o you_o take_v it_o for_o then_o there_o be_v but_o little_a lixivial_a salt_n in_o proportion_n to_o the_o liquid_a the_o resinous_a part_n be_v let_v go_v and_o precipitate_v to_o the_o bottom_n of_o the_o stomach_n as_o in_o the_o case_n of_o the_o spirit_n of_o wine_n so_o dilate_v of_o which_o i_o have_v see_v a_o very_a convince_a instance_n for_o one_o that_o have_v a_o esteem_n of_o lixivial_o in_o this_o case_n not_o only_o according_a to_o helmont_n and_o the_o common_a cry_n to_o correct_v opium_n but_o also_o to_o extract_v its_o virtue_n the_o more_o effectual_o make_v a_o tincture_n of_o opium_n in_o water_n lixiviate_v with_o salt_n of_o wormwood_n whereof_o he_o take_v the_o quantity_n that_o he_o have_v see_v i_o give_v of_o my_o liquid_a panacea_fw-la in_o a_o coffee-dish_n full_a of_o water_n which_o precipitate_v the_o rosin_n in_o the_o stomach_n cause_v he_o to_o vomit_v in_o about_o a_o hour_n after_o and_o continue_v so_o to_o do_v for_o about_o 15_o hour_n by_o which_o you_o plain_o see_v that_o the_o great_a secret_a of_o lixivial_o to_o correct_v opium_n lie_v mere_o in_o its_o division_n of_o the_o rosin_n thereof_o as_o in_o the_o case_n of_o spirit_n of_o wine_n and_o powder_a it_o and_o afterward_o keep_v its_o particle_n asunder_o during_o its_o stay_n at_o stomach_n which_o the_o sapo_n tartareus_fw-la do_v and_o probable_o other_o soap_n may_v do_v very_o well_o for_o the_o several_a reason_n aforesaid_a 3._o dissolution_n of_o opium_n in_o the_o yolk_n of_o a_o rear_n new_o lay_v egg_n by_o pound_v the_o dose_n that_o you_o intend_v to_o take_v with_o a_o little_a quantity_n of_o the_o yolk_n till_o both_o be_v thorough_o mix_v and_o then_o take_v it_o in_o the_o remain_a part_n of_o the_o yolk_n by_o which_o mean_v you_o not_o only_o fine_o divide_v the_o resinous_a part_n of_o the_o opium_n while_o the_o yolk_n of_o the_o egg_n intimate_o mix_v with_o they_o as_o it_o do_v with_o other_o rosin_n and_o turpentine_n but_o send_v along_o with_o it_o into_o the_o stomach_n what_o be_v digestible_a in_o itself_o and_o more_o and_o more_o divide_v and_o separate_v the_o resinous_a part_n and_o high_o contribute_v to_o their_o final_a dissolution_n and_o digestion_n so_o that_o i_o doubt_v not_o but_z you_o will_v find_v this_o new_a ready_a and_o agreeable_a mean_n as_o good_a if_o not_o better_o all_o thing_n consider_v than_o the_o former_a and_o even_o equal_a to_o the_o sapo_n tartareus_fw-la by_o what_o be_v say_v though_o short_a you_o may_v because_o it_o be_v the_o clear_a truth_n of_o thing_n judge_v of_o the_o goodness_n of_o all_o preparation_n of_o opium_n and_o 1._o that_o resinous_a thing_n shall_v not_o be_v add_v to_o opium_n because_o such_o like_o its_o own_o rosin_n render_v it_o more_o indigestible_a and_o apt_a to_o stick_v at_o stomach_n hence_o it_o be_v that_o the_o styrax_fw-mi pill_n have_v resinous_a thing_n in_o it_o and_o crude_a opium_n do_v so_o often_o cause_v dismal_a effect_n though_o forsooth_o much_o esteem_v for_o the_o lung_n cough_n defluxion_n etc._n etc._n for_o have_v such_o balsamic_a resinous_a thing_n as_o styrax_n and_o olibanum_n in_o it_o whereas_o the_o benefit_n be_v from_o the_o opium_n have_v dr._n bates_n know_v the_o cause_n of_o the_o mischief_n of_o opium_n he_o will_v never_o have_v put_v benjamin_n in_o his_o pacifick_n pill_n 2._o that_o all_o preparation_n make_v of_o extract_n in_o spirit_n of_o wine_n be_v to_o be_v reject_v such_o extract_v be_v much_o worse_a than_o crude_a opium_n and_o experimental_o find_v to_o be_v so_o therefore_o our_o common_a london_n laudanum_n be_v make_v of_o opium_n prepare_v in_o spirit_n of_o wine_n be_v no_o commendable_a preparation_n though_o so_o much_o use_v and_o cry_v up_o which_o also_o experience_n prove_v in_o that_o it_o sometime_o cause_v the_o ill_a effect_n of_o opium_n when_o give_v alone_o in_o a_o good_a do_v you_o will_v find_v more_o of_o these_o matter_n when_o you_o come_v to_o chap._n 29._o which_o consist_v of_o general_a rule_n and_o caution_n concern_v the_o use_n of_o opium_n therefore_o though_o i_o may_v add_v some_o useful_a observation_n i_o put_v a_o end_n to_o this_o matter_n at_o present_a for_o that_o reason_n and_o because_o what_o be_v to_o be_v true_o do_v in_o the_o preparation_n of_o opium_n be_v very_o evident_a from_o what_o be_v say_v since_o the_o cause_n of_o the_o ill_a effect_n of_o opium_n be_v now_o certain_o know_v to_o be_v its_o rosin_n to_o the_o separation_n or_o due_a alteration_n of_o which_o so_o as_o to_o cause_v it_o to_o pass_v the_o stomach_n without_o adhesion_n or_o offence_n by_o
part_n themselves_o do_v also_o due_o contract_n which_o opium_n hinder_v 6._o you_o have_v much_o the_o same_o reason_n not_o to_o give_v they_o soon_o after_o other_o large_a evacuation_n where_o a_o due_a contraction_n of_o the_o part_n be_v requisite_a as_o after_o tapping_n or_o paracentesis_n in_o dropsy_n childbirth_n etc._n etc._n 7._o opiate_n be_v best_a give_v in_o the_o morning_n to_o cause_n euphory_n or_o brisk_a effect_n because_o the_o refreshment_n gain_v by_o the_o night_n sleep_n do_v not_o only_o concur_v towards_o euphory_n and_o briskness_n but_o also_o much_o oppose_v sleepiness_n and_o drowsiness_n which_o be_v not_o consistent_a with_o brisk_a effect_n vi_o as_o to_o person_n 1._o it_o be_v not_o convenient_a to_o give_v opiate_n to_o person_n very_o young_a or_o very_a old_a 2._o they_o agree_v better_o with_o man_n than_o woman_n or_o child_n with_o man_n of_o a_o robu_v and_o hard_a rather_o than_o of_o a_o weak_a fine_a tender_a and_o soft_a texture_n with_o such_o as_o have_v a_o strong_a digestion_n than_o a_o weak_a and_o in_o general_a with_o the_o strong_a rather_o than_o the_o weak_a therefore_o 3._o never_o give_v they_o to_o person_n that_o be_v very_o weak_a especial_o if_o they_o take_v or_o digest_v no_o sustenance_n or_o extreme_o little_a for_o reason_n already_o give_v nor_o to_o such_o as_o be_v near_o their_o end_n or_o almost_o expire_a ☞_o except_o it_o be_v for_o want_v of_o opium_n or_o by_o extremity_n of_o contraction_n by_o terror_n pain_n cold_a convulsion_n etc._n etc._n for_o than_o it_o will_v do_v wonder_n in_o preserve_a people_n that_o be_v otherwise_o past_a all_o hope_n by_o relax_v take_v away_o pain_n contraction_n etc._n etc._n 4._o it_o be_v not_o so_o agreeable_a to_o the_o very_a fat_a or_o moist_a because_o they_o may_v be_v over-relaxed_n nor_o to_o the_o very_a lean_a and_o dry_a etc._n etc._n especial_o to_o cause_n sleep_n because_o it_o be_v apt_a to_o irritate_fw-la and_o actuate_v their_o spirit_n too_o much_o by_o which_o mean_v sleep_n be_v much_o hinder_v vii_o as_o to_o malady_n and_o disease_n etc._n etc._n i._o opiate_n be_v not_o convenient_a in_o relaxation_n as_o such_o as_o general_a palsy_n hemiphlegia_n palsy_n of_o the_o eye_n deadness_n of_o they_o dilatation_n of_o the_o pupil_n relaxation_n of_o the_o tympan_n of_o the_o ear_n of_o one_o side_n of_o the_o face_n which_o make_v the_o other_o side_n contract_n and_o and_o so_o draw_v the_o face_n awry_o for_o it_o be_v not_o a_o spasm_n or_o convulsion_n as_o man_n imagine_v of_o the_o contract_a side_n but_o a_o resolution_n of_o the_o other_o which_o permit_v the_o antagonist_n muscle_n of_o that_o side_n to_o contract_n without_o opposition_n and_o draw_v the_o face_n towards_o the_o strong_a or_o sound_a side_n relaxation_n of_o the_o uuula_fw-la or_o the_o annex_v value_n which_o last_o be_v know_v by_o snuffle_v without_o any_o other_o evident_a cause_n or_o by_o observe_v that_o it_o do_v not_o shut_v in_o sound_a u_o in_o but_o cut_z etc._n etc._n by_o itself_o relaxation_n of_o the_o larynx_n and_o windpipe_n which_o be_v know_v by_o a_o hoarse_a kind_n of_o whisper_n without_o a_o cold_a or_o any_o evident_a cause_n of_o the_o pharynx_n or_o gullet_n which_o be_v know_v by_o a_o depravation_n of_o swallow_v without_o pain_n or_o tumour_n or_o any_o evident_a cause_n a_o paralytical_a asthma_n or_o difficulty_n of_o breathe_v wherein_o man_n heave_v the_o shoulder_n without_o any_o apparent_a cause_n relaxation_n of_o the_o stomach_n as_o when_o meat_n stay_v too_o long_o at_o stomach_n etc._n etc._n a._n palsy_n of_o the_o intestine_n or_o gut_n as_o when_o one_o be_v bind_v and_o can_v refer_v it_o to_o any_o other_o cause_n of_o the_o bladder_n when_o one_o can_v make_v water_n without_o any_o other_o cause_n to_o refer_v it_o to_o relaxation_n of_o the_o sphincter_n of_o the_o bladder_n and_o anâ—_n that_o be_v when_o urine_n or_o ordure_n fall_v from_o one_o involuntary_o nor_o be_v they_o convenient_a in_o bath_n unless_o great_a relaxation_n as_o for_o passage_n of_o the_o stone_n etc._n etc._n be_v intend_v nor_o in_o rupture_n as_o bronchocele_v of_o the_o windpipe_n exomphalos_n of_o the_o navel_n bubonocele_n of_o the_o groin_n or_o the_o fall_n of_o humour_n gut_n fat_a etc._n etc._n into_o the_o scrotum_fw-la or_o of_o the_o fundament_n womb_n or_o the_o vagina_n etc._n etc._n except_o it_o be_v to_o reduce_v they_o nor_o in_o lunation_n sprain_n laxity_n and_o weakness_n of_o joint_n limb_n back_o etc._n etc._n extension_n of_o nerve_n tendon_n ligament_n etc._n etc._n nor_o where_o relaxation_n do_v or_o may_v improve_v the_o distemper_n or_o do_v harm_n as_o in_o apoplectical_a and_o soporose_a case_n as_o coma_n caros_n lethargy_n etc._n etc._n weakness_n of_o memory_n stupidity_n morosiâ—_n nightmare_n drunkenness_n etc._n etc._n syncopes_fw-la and_o faint_n from_o relaxation_n as_o the_o original_a cause_n as_o from_o excess_n of_o joy_n pleasure_n large_a evacuation_n when_o the_o part_n can_v well_o and_o due_o contract_v upon_o what_o remain_v as_o after_o childbirth_n profuse_a hemorrhage_n tapping_n or_o paracentesis_n or_o any_o large_a evacuation_n of_o humour_n in_o dropsy_n of_o the_o belly_n breast_n or_o head_n nor_o as_o have_v be_v hint_v in_o dropsy_n though_o without_o any_o such_o evacuation_n unless_o it_o be_v upon_o some_o special_a consideration_n of_o the_o learned_a nor_o in_o tremble_n or_o shake_v of_o the_o head_n or_o hand_n etc._n etc._n from_o weakness_n as_o in_o old_a age_n nor_o in_o flux_n from_o relaxation_n as_o too_o much_o sweat_n gonorrhaea_n simplex_n diabetes_n nocturnal_a pollution_n chylous_a flux_n lientery_n involuntary_a flux_n of_o urine_n or_o ordure_n and_o some_o sort_n of_o immoderate_a flux_n of_o the_o menses_fw-la or_o lochia_n which_o owe_v their_o cause_n to_o relaxation_n or_o aptitude_n to_o abortion_n from_o that_o cause_n and_o indeed_o general_o in_o woman_n with_o child_n lest_o it_o shall_v cause_v abortion_n by_o relax_v the_o neck_n of_o the_o womb._n or_o where_o contraction_n be_v beneficial_a as_o to_o empty_v a_o foul_a or_o replete_a stomach_n choler_n etc._n etc._n by_o vomit_v or_o stool_n or_o a_o ill_a humour_n any_o way_n therefore_o ii_o opiate_n be_v not_o convenient_a when_o grievous_a sensation_n be_v useful_a as_o to_o excite_v expectoration_n when_o matter_n threaten_v suffocation_n in_o vomicas_fw-la pleurisy_n peripneumonias_n consumption_n spit_v of_o blood_n etc._n etc._n when_o hunger_n call_v for_o food_n and_o restaurative_n that_o of_o stuff_v at_o stomach_n excite_v vomit_v that_o of_o urine_n solicit_v we_o to_o a_o due_a excretion_n thereof_o that_o of_o ill_a matter_n at_o gut_n cause_v a_o evacuation_n thereof_o so_o that_o when_o a_o crisis_n be_v to_o be_v by_o the_o help_n of_o grievous_a sensation_n or_o irritation_n opiate_n be_v not_o convenient_a for_o it_o take_v off_o the_o sense_n of_o irritation_n but_o when_o a_o crisis_n be_v to_o be_v by_o relaxation_n as_o by_o open_v the_o pore_n to_o cause_n sweat_n perspiration_n etc._n etc._n then_o be_v it_o of_o excellent_a use_n so_o that_o great_a question_n that_o have_v very_o much_o puzzle_v the_o learned_a whether_o opium_n be_v convenient_a before_o a_o crisis_n &_o c_o be_v plain_o and_o mechanical_o answer_v iii_o opiate_n be_v not_o convenient_a where_o titillation_n by_o the_o acrimony_n of_o volatile_a salt_n be_v the_o cause_n of_o the_o disease_n as_o in_o troublesome_a erection_n priapism_n nocturnal_a pollution_n venereal_a fury_n too_o much_o salacity_n and_o titillation_n itch_n of_o the_o uterus_fw-la scrotum_fw-la penis_n skin_n in_o general_n etc._n etc._n iv_o i_o scarce_o need_v tell_v any_o that_o opiate_n be_v inconvenient_a when_o the_o meconium_n of_o child_n shall_v be_v evacuate_v or_o when_o one_o be_v bind_v in_o body_n or_o apt_a to_o be_v so_o but_o there_o may_v be_v a_o time_n when_o the_o learned_a physician_n may_v think_v fit_a to_o give_v they_o even_o to_o the_o costive_a in_o urgent_a case_n for_o he_o can_v order_v somewhat_o along_o with_o they_o or_o soon_o after_o to_o open_v the_o body_n who_o may_v also_o see_v cause_n sometime_o to_o vary_v from_o these_o general_a rule_n when_o necessity_n and_o good_a reason_n direct_v he_o so_o to_o do_v though_o they_o be_v nevertheless_o general_a in_o their_o nature_n and_o not_o to_o be_v transgress_v without_o special_a cause_n and_o mature_a deliberation_n v._o opiate_n be_v not_o so_o convenient_a where_o there_o be_v much_o slimy_a moist_a and_o phlegmatic_a humour_n by_o reason_n that_o the_o part_n be_v subject_a in_o such_o case_n to_o be_v too_o much_o relax_v i_o have_v be_v the_o full_a especial_o upon_o the_o head_n of_o disease_n that_o i_o may_v hereafter_o have_v nothing_o to_o do_v but_o to_o show_v the_o beneficial_a use_n of_o opiate_n due_o prepare_v more_o particular_o of_o the_o panacea_n
the_o pore_n therefore_o 1._o it_o be_v of_o excellent_a use_n to_o carry_v away_o noxious_a vapour_n or_o effluvia_n by_o the_o pore_n of_o the_o skin_n to_o prevent_v putrefaction_n and_o cure_v they_o to_o carry_v off_o venomous_a particle_n in_o the_o plague_n infectious_a distemper_n bite_n of_o serpent_n mad_a dog_n etc._n etc._n ill_a fume_n wind_n in_o the_o blood_n or_o habit_n of_o the_o body_n that_o cause_v stitch_n tumour_n etc._n etc._n 2._o to_o carry_v off_o noxious_a humour_n the_o same_o way_n especial_o such_o as_o stagnate_n or_o offend_v in_o the_o habit_n of_o the_o body_n as_o in_o cold_n intercutaneous_a water_n leâ—cophlegmatia_n and_o sometime_o in_o dropsy_n as_o dr._n willis_n observe_v in_o declination_n of_o disease_n to_o carry_v off_o the_o concoct_v morbid_v matter_n in_o rheumatism_n and_o gout_n particular_o that_o which_o be_v call_v the_o wind_n gout_n 3._o when_o perspiration_n be_v any_o way_n hinder_v as_o by_o grievous_a passion_n sensation_n or_o pain_n acid_a austere_a or_o cold_a humour_n by_o which_o many_o disease_n be_v cause_v thus_o it_o be_v very_o useful_a in_o grief_n sorrow_n anxiety_n solicitude_n melancholy_a panic_n fear_n gachexy_n scurvy_n hypochondriacal_a case_n wherein_o it_o perform_v wonderful_o when_o all_o thing_n fail_v as_o you_o find_v in_o chap._n 24._o 4._o to_o promote_v the_o menses_fw-la or_o lochia_n when_o stop_v by_o reason_n of_o the_o constriction_n of_o the_o pore_n by_o such_o grievous_a passion_n or_o sensation_n or_o by_o acid_n austere_a or_o cold_a humour_n external_a cold_a etc._n etc._n by_o its_o relax_a and_o open_v the_o pore_n and_o way_n and_o solicit_v the_o part_n by_o a_o gentle_a agreeable_a titillation_n hence_o some_o just_o call_v it_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o be_v a_o opener_n of_o the_o mouth_n of_o the_o vein_n or_o bloud-vessel_n by_o which_o mean_v as_o have_v be_v show_v puberty_n coition_n etc._n etc._n do_v kind_o and_o natural_o cause_v the_o menses_fw-la to_o flow_v while_o the_o same_o relaxation_n cause_v a_o increase_n of_o blood_n as_o it_o do_v of_o milk_n by_o widen_v the_o vessel_n this_o be_v all_o mechanical_a truth_n that_o will_v answer_v upon_o experience_n as_o the_o most_o ingenious_a dr._n edw._n brown_n can_v witness_v who_o be_v the_o only_a man_n as_o far_o as_o i_o know_v that_o seem_v to_o have_v this_o practice_n 5._o it_o promote_v urine_n by_o the_o like_a open_n or_o relax_v of_o the_o pore_n of_o the_o kidney_n by_o its_o titillate_v volatile_a salt_n as_o cantharides_n bee_n pismire_n millepedes_n etc._n etc._n do_v 6._o it_o may_v probable_o be_v of_o great_a use_n in_o cutaneous_a distemper_n either_o by_o take_v large_a quantity_n of_o proper_a liquid_n and_o sweat_v they_o out_o again_o by_o its_o help_n to_o wash_v of_o ill_a particle_n or_o to_o open_v the_o pore_n for_o the_o admission_n of_o external_a medicament_n note_v that_o they_o be_v natural_a flux_n it_o promote_v and_o unnatural_a one_o that_o it_o stop_v which_o prove_v its_o operate_n as_o a_o entire_a friend_n to_o nature_n both_o way_n i._o the_o form_n may_v be_v which_o you_o please_v or_o be_v most_o agreeable_a to_o the_o patient_n ii_o the_o do_v moderate_a except_o it_o be_v when_o extraordinary_a relaxation_n or_o open_n of_o the_o pore_n be_v desire_v iii_o the_o vehicle_n shall_v be_v such_o as_o be_v proper_a to_o prepare_v the_o humour_n to_o pass_v by_o sweat_n or_o insensible_a perspiration_n or_o the_o blood_n by_o the_o menses_fw-la and_o lochia_n therefore_o shall_v general_o speak_v consist_v of_o attenuate_a thing_n as_o volatile_a spirit_n and_o in_o the_o plague_n venomous_a and_o contagious_a case_n of_o alexipharmack_n of_o diuretic_n to_o promote_v urine_n and_o so_o in_o all_o case_n of_o what_o be_v proper_a in_o the_o respective_a humour_n for_o their_o exit_fw-la or_o passage_n iv_o the_o time_n because_o sleep_n conduce_v to_o open_v the_o pore_n may_v be_v at_o the_o due_a distance_n before_o bedtime_n but_o that_o hinder_v not_o but_o it_o may_v be_v give_v when_o there_o be_v occasion_n at_o any_o other_o time_n in_o the_o plague_n it_o shall_v be_v so_o often_o give_v as_o to_o keep_v the_o pore_n always_o open_a mayern_n glve_v a_o instance_n of_o a_o physician_n that_o have_v all_o sign_n of_o death_n petechiae_fw-la a_o carbuncle_n etc._n etc._n who_o recover_v by_o take_v laudanum_n 6_o time_n a_o day_n i_o suppose_v 24_o hour_n or_o the_o natural_a day_n be_v mean_v thereby_o v._o the_o regimen_n must_v be_v such_o as_o be_v proper_a convenient_a and_o usual_a in_o the_o respective_a case_n for_o it_o be_v endless_a to_o mention_v all_o it_o require_v a_o volume_n to_o cause_n sweat_n much_o temperate_a liquid_n must_v be_v always_o give_v especial_o in_o fever_n or_o dry_a body_n as_o the_o hypochondriacal_a etc._n etc._n most_o part_n of_o the_o liquid_n shall_v be_v give_v before_o the_o opiate_n that_o they_o may_v have_v time_n to_o get_v into_o the_o blood_n by_o that_o time_n the_o opiate_n operate_v which_o do_v so_o as_o be_v show_v while_o it_o be_v at_o stomach_n to_o move_v the_o menses_fw-la proper_a mean_n shall_v be_v use_v for_o a_o due_a time_n before_o the_o use_v thereof_o because_o the_o effect_v expect_v in_o this_o case_n from_o opiate_n be_v only_o to_o open_v the_o way_n or_o pore_n so_o humour_n in_o leucophlegmatia_n &c._n &c._n shall_v be_v due_o prepare_v for_o the_o like_a reason_n to_o cause_n perspiration_n it_o be_v convenient_a in_o cold_a constitution_n and_o old_a people_n gentle_o to_o warm_v the_o blood_n with_o 2_o or_o 3_o glass_n of_o generous_a wine_n a_o little_a garlic_n onion_n selery_n or_o the_o like_a to_o attenuate_v and_o cause_v evaporation_n which_o heat_v promote_v but_o if_o you_o overheat_v the_o blood_n it_o hinder_v perspiration_n by_o its_o grow_a grievous_a for_o what_o be_v so_o cause_v contraction_n and_o close_n of_o the_o pore_n note_v that_o nothing_o can_v be_v so_o good_a to_o cause_v perspiration_n or_o sweat_n because_o it_o not_o only_o open_v the_o pore_n but_o take_v away_o any_o grievous_a passion_n or_o sensation_n that_o may_v close_v they_o and_o atenuate_v resolve_n etc._n etc._n by_o its_o volatile_a salt_n chap._n xxxviii_o of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n as_o a_o titillative_a this_o it_o do_v as_o be_v show_v by_o its_o volatile_a salt_n as_o cantharides_n bee_n pismire_n sem._n viril_n etc._n etc._n therefore_o 1._o it_o be_v of_o great_a use_n to_o excite_v to_o venery_n cause_n erection_n to_o actuate_v a_o dull_a semen_n for_o the_o sake_n of_o lawful_a propagation_n 2._o to_o increase_v the_o semen_n 1._o by_o the_o titillation_n of_o the_o venereal_a part_n which_o invite_v it_o thither_o by_o the_o agitation_n thereof_o as_o frication_n of_o the_o breast_n and_o those_o part_n cause_n increase_n of_o milk_n and_o the_o semen_n 2._o by_o the_o pleasure_n thereof_o relax_v the_o part_n which_o cause_v a_o great_a flux_n of_o it_o as_o of_o milk_n to_o the_o breast_n and_o nourishment_n to_o any_o part._n it_o be_v observable_a how_o desirous_a rachel_n be_v barren_a be_v of_o the_o opiate_n call_v mandrake_n so_o that_o she_o part_v with_o her_o belove_a husband_n to_o her_o sister_n leah_n for_o a_o night_n to_o purchase_v it_o whether_o it_o be_v any_o mean_n to_o cause_v she_o to_o conceive_v which_o she_o do_v afterward_o be_v not_o to_o be_v determine_v though_o it_o seem_v not_o altogether_o unlikely_a 3._o it_o be_v use_n to_o increase_v milk_n be_v speak_v of_o in_o the_o chapter_n of_o its_o use_n to_o relax_v only_o it_o do_v it_o here_o as_o titillate_v and_o there_o as_o relax_v 4._o it_o conduce_v to_o move_v the_o menses_fw-la by_o its_o titillation_n 5._o the_o titillation_n of_o its_o volatile_a salt_n as_o cantharides_n etc._n etc._n do_v move_v we_o to_o urine_n i._o the_o form_n be_v whole_o indifferent_a ii_o the_o dose_n must_v be_v large_a and_o general_o great_a than_o any_o i_o have_v mention_v and_o possible_o require_v a_o repetition_n thereof_o to_o excite_v to_o venery_n though_o i_o shall_v not_o prescribe_v any_o more_o than_o i_o have_v in_o the_o table_n of_o dose_n but_o leave_v it_o to_o judicious_a physician_n to_o do_v as_o they_o think_v â—it_a where_o there_o be_v a_o just_a cause_n for_o its_o use_n which_o i_o will_v not_o expose_v to_o every_o lustful_a goat_n it_o be_v not_o unlikely_a but_o one_o great_a cause_n of_o the_o ignorance_n of_o its_o use_n to_o excite_v venery_n in_o these_o western_a part_n of_o the_o world_n may_v be_v the_o smallness_n of_o the_o dose_n that_o we_o use_v beside_o the_o reason_n mention_v in_o chap._n 8._o and_o that_o such_o circumstance_n may_v occasion_v the_o dispute_n and_o contradiction_n that_o have_v be_v about_o the_o effect_n of_o opium_n whereas_o there_o be_v