etc._n as_o wine_n hot_a liquor_n and_o opium_n do_v 12._o opium_n do_v very_o much_o open_v the_o pore_n and_o cause_n perspiration_n etc._n etc._n which_o only_a heat_n as_o that_o in_o bath_n bagnio_n hot_a house_n and_o hot_a thing_n do_v but_o cold_a shut_v the_o pore_n as_o all_o know_v therefore_o 13._o opium_n cure_v and_o prevent_v cold_n which_o be_v another_o argument_n of_o its_o heat_n 14._o it_o be_v a_o great_a aphrodisiack_a or_o exciter_n to_o venery_n which_o cold_a thing_n chill_a but_o hot_a thing_n as_o cantharides_n bee_n pismire_n onion_n garlic_n leek_n rocket_n squill_n horse_n radish_n sem._n human._n etc._n etc._n do_v promote_v 15._o nothing_o cause_v indolence_n give_v internal_o but_o wine_n hot_a liquor_n etc._n etc._n as_o i_o can_v think_v of_o and_o opium_n cause_v it_o much_o after_o the_o same_o manner_n as_o wine_n do_v first_o cause_v mirth_n and_o jollity_n and_o upon_o increase_n of_o quantity_n very_o considerable_a indolence_n it_o be_v true_a that_o cold_a will_v external_o cause_v a_o stupor_n if_o it_o be_v intense_a so_o as_o to_o constringe_v the_o part_n and_o exclude_v the_o spirit_n but_o otherwise_o it_o make_v the_o feel_v more_o nice_a as_o all_o know_v by_o experience_n because_o every_o little_a hurt_n affect_v we_o more_o when_o we_o be_v cold_a than_o hot_a but_o this_o be_v not_o the_o case_n of_o relax_a opium_n which_o be_v use_v internal_o to_o take_v away_o pain_n as_o wine_n etc._n etc._n 16._o nothing_o take_v away_o the_o effect_n of_o opium_n or_o drunkeness_n better_o than_o cold_a thing_n internal_o and_o external_o as_o acid_n dip_v in_o cold_a water_n etc._n etc._n 17._o opium_n relax_n all_o part_n which_o heat_n do_v and_o cold_a constringe_n as_o be_v intimate_v 18._o wedelius_n confess_v though_o it_o make_v against_o what_o he_o say_v that_o he_o never_o observe_v a_o soporose_n distemper_n where_o there_o be_v not_o a_o preternatural_a heat_n opiolog_fw-la lib._n 1._o sect._n 1_o cap._n 12._o p._n 46._o 19_o if_o it_o cause_v sleep_n by_o its_o cold_a quality_n than_o all_o thing_n that_o be_v cold_a will_v do_v it_o proportionable_o cucumber_n purslane_n etc._n etc._n will_v be_v so_o great_a hypnotick_n that_o we_o shall_v not_o be_v able_a to_o eat_v a_o drachm_n of_o they_o but_o that_o they_o will_v cause_v a_o great_a sopor_fw-la but_o there_o be_v no_o such_o thing_n and_o hot_a thing_n be_v much_o more_o apt_a to_o cause_v sleep_n or_o a_o sopor_fw-la as_o wine_n hot_a spirit_n onion_n garlic_n and_o such_o like_a 20._o opium_n cause_v a_o redness_n or_o efflorescence_n of_o the_o skin_n make_v it_o sensible_o warm_a as_o heat_n wine_n and_o strong_a liquor_n do_v 21._o it_o cause_v also_o a_o itch_a of_o the_o skin_n which_o only_o hot_a thing_n do_v 22._o half_n a_o drachm_n of_o opium_n in_o clyster_n have_v cause_v a_o violent_a heat_n in_o the_o gut_n 23._o it_o stop_v diarrheas_n or_o looseness_n which_o cold_a cause_n 24._o it_o stop_v defluxion_n cough_n etc._n etc._n which_o cold_a cause_n 25._o to_o pin_v up_o all_o its_o predominant_a principle_n appear_v by_o autopsie_n upon_o its_o chemical_a analysis_n to_o be_v volatile_a salt_n and_o sulphur_n beside_o this_o opinion_n of_o the_o coldness_n of_o opium_n be_v very_o much_o explode_v and_o indeed_o it_o be_v so_o apparent_o false_a and_o absurd_a that_o i_o shall_v not_o have_v think_v it_o worth_a while_n to_o argue_v against_o it_o but_o that_o it_o lay_v so_o in_o my_o way_n that_o regular_o i_o can_v not_o well_o avoid_v it_o without_o breach_n of_o order_n and_o method_n i_o may_v have_v add_v that_o it_o resolve_v attenuate_v etc._n etc._n but_o it_o be_v needless_a to_o say_v any_o more_o it_o be_v very_o false_a and_o erroneous_a that_o it_o stop_v flux_n by_o incrassate_v and_o bind_v which_o be_v account_v cold_a quality_n if_o so_o how_o shall_v it_o stop_v they_o when_o pound_n of_o incrassative_n and_o binder_n have_v fail_v though_o the_o opium_n be_v give_v only_o in_o the_o quantity_n of_o a_o grain_n or_o two_o how_o shall_v it_o stop_v or_o moderate_a flux_n even_o while_o it_o be_v yet_o at_o stomach_n as_o it_o most_o certain_o do_v it_o bear_v as_o etmuller_n well_o observe_v no_o proportion_n to_o the_o blood_n and_o humour_n to_o have_v any_o effect_n that_o may_v be_v remarkable_a upon_o they_o for_o a_o grain_n be_v but_o as_o 1_o to_o 115200_o to_o the_o blood_n of_o he_o that_o have_v 20_o pound_n of_o blood_n which_o a_o ordinary_a man_n have_v beside_o how_o can_v altenuative_n resolver_n and_o discusser_n incrassate_fw-it or_o bind_z but_o more_o especial_o how_o can_v so_o great_a a_o relaxer_n of_o part_n be_v a_o constringer_n thereof_o that_o be_v perfect_a contradiction_n and_o how_o can_v a_o mere_a sal_fw-la volatile_a oleosum_fw-la in_o which_o all_o its_o virtue_n lie_v as_o will_v plain_o appear_v thicken_v and_o bind_v the_o truth_n be_v that_o it_o stop_v flux_n as_o sleep_n do_v by_o take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o solicit_v the_o part_n to_o contract_n and_o so_o to_o extrude_v and_o squeeze_v they_o out_o it_o promote_v perspiration_n by_o relax_v the_o pore_n as_o sleep_n do_v it_o also_o seem_v to_o thicken_v rheum_n as_o sleep_n do_v because_o it_o cause_v sleep_n or_o at_o least_o take_v away_o a_o sense_n of_o the_o irritation_n of_o the_o rheum_n be_v thereby_o suffer_v to_o stay_v till_o it_o thicken_v by_o the_o heat_n of_o the_o body_n the_o irritation_n also_o at_o windpipe_n be_v less_o because_o the_o flux_n of_o the_o rheum_n be_v moderate_v for_o the_o reason_n aforesaid_a but_o of_o these_o thing_n more_o full_o when_o we_o come_v to_o explain_v the_o cause_n or_o cause_n of_o the_o effect_n of_o opium_n chap._n x._o it_o be_v prove_v that_o opium_n send_v no_o fume_n etc._n etc._n from_o the_o stomach_n to_o the_o head_n brain_n etc._n etc._n and_o therefore_o that_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n etc._n etc._n by_o that_o mean_n though_o the_o opinion_n of_o the_o cold_a of_o opium_n be_v much_o explode_v that_o of_o fume_n vapour_n or_o aura_n arise_v from_o the_o opium_n at_o stomach_n and_o mount_v up_o to_o the_o brain_n etc._n etc._n be_v as_o much_o receive_v and_o embrace_v i_o know_v none_o but_o such_o as_o think_v it_o absolute_o necessary_a consider_v that_o it_o be_v most_o certain_a and_o allow_v by_o all_o observe_a man_n that_o opium_n produce_v all_o or_o most_o of_o its_o effect_n while_o it_o be_v at_o stomach_n that_o the_o genus_fw-la neruâ—sum_fw-la be_v most_o concern_v in_o its_o operation_n and_o that_o as_o be_v say_v there_o be_v no_o operation_n or_o action_n but_o by_o contact_n so_o that_o the_o modern_n acquiesce_v in_o the_o necessity_n of_o its_o operate_n that_o way_n because_o they_o can_v conceive_v no_o other_o which_o be_v no_o proof_n but_o a_o defect_n of_o their_o conception_n look_v upon_o it_o as_o invincible_a and_o uncontrollable_a evidence_n oâ—_n its_o operate_n by_o detachment_n of_o fume_n or_o 〈◊〉_d send_v up_o to_o the_o brain_n from_o the_o stomach_n which_o appear_v so_o undeniable_o conclusive_a that_o neither_o the_o want_n of_o a_o sensible_a passage_n nor_o any_o other_o inconvenience_n signify_v any_o thing_n with_o they_o to_o the_o contrary_a therefore_o it_o become_v a_o establish_a foundation_n by_o common_a consent_n only_o they_o differ_v as_o be_v show_v in_o the_o manner_n how_o those_o fume_n produce_v the_o effect_n of_o opium_n and_o well_o they_o may_v see_v there_o be_v no_o such_o thing_n nor_o possibility_n if_o they_o be_v of_o ever_o explicate_v the_o various_a effect_n of_o opium_n by_o that_o mean_n as_o will_v manifest_o appear_v i_o confess_v that_o if_o opium_n operate_v by_o such_o fume_n pass_v from_o the_o stomach_n to_o the_o brain_n etc._n etc._n it_o will_v be_v easy_a to_o conceive_v how_o it_o shall_v diminish_v or_o disable_v nay_o utter_o ruin_v the_o animal_n spirit_n and_o indeed_o impossible_a rational_o to_o conceive_v how_o they_o can_v do_v otherwise_o but_o then_o the_o enliven_a invigorate_n and_o encourage_v effect_n of_o opium_n which_o be_v its_o constant_a and_o most_o genuine_a off_o spring_n will_v lie_v upon_o our_o hand_n without_o any_o possibility_n of_o give_v a_o account_n thereof_o for_o certain_o dull_a heavy_a unnatural_a undigested_a and_o cloudy_a fume_n or_o vapour_n can_v not_o advantage_v the_o animal_n spirit_n cause_v a_o triumph_n or_o ovation_n thereof_o at_o their_o access_n courage_n serenity_n promptitude_n magnanimity_n euphory_n inclination_n to_o venery_n etc._n etc._n which_o we_o be_v most_o oblige_v to_o regard_n as_o be_v its_o most_o natural_a and_o proper_a effect_n this_o opinion_n of_o the_o modern_n do_v presume_v or_o suppose_v for_o they_o prove_v nothing_o first_o that_o fume_n
a_o very_o long_o and_o lavish_a use_n thereof_o the_o inconvenience_n of_o leave_v off_o the_o use_n of_o opium_n do_v bear_v a_o certain_a proportion_n to_o the_o time_n and_o quantity_n that_o it_o have_v be_v use_v in_o 1._o note_v that_o the_o turk_n do_v drink_v some_o water_n always_o after_o the_o take_n of_o opium_n as_o be_v the_o best_a menstruum_fw-la to_o dissolve_v it_o 2._o note_v that_o it_o be_v usual_a with_o they_o to_o take_v a_o drachm_n in_o the_o morning_n and_o so_o much_o in_o the_o afternoon_n and_o so_o may_v we_o as_o well_o as_o they_o if_o use_v to_o it_o and_o it_o be_v a_o very_a silly_a say_n that_o you_o will_v find_v in_o author_n that_o they_o be_v better_a able_a to_o bear_v it_o because_o of_o the_o climate_n etc._n etc._n whereas_o the_o more_o northern_a person_n be_v better_a able_a to_o take_v it_o than_o the_o southern_a as_o will_v hereafter_o appear_v most_o plain_o i_o be_o tell_v of_o one_o near_o banbury_n that_o take_v two_o ounce_n a_o day_n 3._o note_v that_o among_o the_o effect_n of_o opium_n may_v be_v observe_v many_o seem_a contradiction_n yet_o be_v there_o nothing_o more_o certain_a than_o the_o several_a different_a matter_n of_o fact_n which_o no_o doubt_n have_v be_v a_o great_a cause_n to_o puzzle_v the_o world_n about_o it_o and_o to_o run_v man_n into_o strange_a absurdity_n concern_v its_o operation_n and_o all_o to_o deviate_v so_o far_o from_o the_o truth_n that_o nothing_o in_o nature_n can_v be_v far_o unless_o you_o will_v say_v that_o heat_n cool_v or_o what_o please_v the_o sensitive_a soul_n be_v at_o the_o same_o time_n abhor_v by_o it_o now_o because_o these_o seem_a contradiction_n in_o the_o effect_n of_o opium_n be_v the_o great_a rub_n to_o be_v meet_v with_o and_o that_o the_o reader_n may_v take_v the_o better_a estimate_n of_o the_o undertake_n and_o my_o explication_n of_o its_o effect_n when_o i_o come_v to_o it_o i_o shall_v not_o fear_v to_o enumerate_v they_o distinct_o though_o they_o will_v make_v the_o strange_a catalogue_n of_o riddle_n that_o ever_o be_v see_v trust_v in_o he_o that_o create_v this_o wonderful_a medicament_n that_o he_o will_v enable_v i_o to_o explain_v all_o its_o effect_n the_o seem_a contradiction_n in_o the_o effect_n of_o opium_n 1._o it_o cause_v sleep_v and_o watch_v 2._o it_o cause_n and_o prevent_v sweat_n 3._o it_o relax_n and_o stop_v looseness_n 4._o it_o stop_v flux_n and_o cause_n that_o of_o sweat_n etc._n etc._n 5._o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v by_o that_o sense_n to_o venery_n 6._o it_o cause_v stupidity_n and_o promptitude_n in_o business_n cloudiness_n and_o serenity_n of_o mind_n 7._o it_o excite_v the_o spirit_n and_o quiet_v they_o 8._o it_o be_v very_o hot_a yet_o cool_v in_o fever_n 9_o it_o be_v hot_a and_o bitter_a yet_o lessen_v appetite_n even_o in_o cold_a stomach_n 10._o it_o stop_v and_o promote_v urine_n 11._o it_o relax_n and_o weaken_v yet_o enable_v we_o to_o undergo_v labour_n journey_n etc._n etc._n 12._o it_o cause_n and_o prevent_v abortion_n 13._o it_o stop_v vomit_v above_o all_o thing_n yet_o cause_n most_o violent_a tedious_a and_o dangerous_a vomit_n 14._o it_o stop_v purge_v in_o a_o most_o eminent_a manner_n yet_o sometime_o cause_v it_o 15._o it_o be_v very_o acrimonious_a yet_o as_o all_o say_v obtund_v acrimony_n however_o it_o allay_v pain_n proceed_v from_o acrimony_n 16._o it_o cause_v a_o furious_a madness_n yet_o compose_v the_o spirit_n above_o all_o thing_n 17._o it_o cause_v 〈◊〉_d yet_o sometime_o cure_v they_o as_o willis_n say_v 18._o it_o cause_v palsy_n yet_o have_v i_o know_v it_o to_o cure_v a_o palsy_n 19_o it_o cause_v dryness_n in_o the_o mouth_n yet_o take_v off_o thirst_n in_o fever_n 20._o it_o cure_v and_o cause_v a_o hiccough_n 21._o it_o stanche_n blood_n yet_o cause_v the_o blood_n to_o come_v outward_a as_o appear_v by_o the_o efflorescence_n or_o redness_n of_o the_o skin_n that_o it_o cause_n yet_o move_v the_o menses_fw-la and_o lochia_n 22._o we_o have_v many_o instance_n of_o it_o promote_a and_o hinder_v critical_a motion_n 23._o it_o raise_v very_o weak_a people_n when_o nothing_o beside_o will_v do_v it_o yet_o it_o kill_v other_o weak_a people_n 24._o it_o cause_n and_o cure_n convulsion_n 25._o it_o cause_v relaxation_n and_o contraction_n of_o the_o same_o part_n 26._o it_o relax_n yet_o cause_v rigidity_n tension_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n thus_o have_v i_o fair_o and_o faithful_o lay_v the_o whole_a onus_fw-la of_o the_o operation_n effect_n and_o contradictory_n phenomena_n of_o opium_n upon_o my_o shoulder_n however_o i_o come_v off_o and_o clear_v myself_o of_o the_o intricacy_n maze_n and_o cross_a effect_n thereof_o by_o explain_v they_o which_o none_o upon_o the_o view_n thereof_o will_v think_v possible_a and_o none_o before_o i_o dare_v as_o much_o as_o enumerate_v for_o that_o end_n chap._n vii_o the_o author_n contrive_v a_o compendious_a way_n of_o examine_v all_o opinion_n concern_v the_o operation_n of_o opium_n have_v without_o any_o sly_a or_o sordid_a evasion_n or_o considerable_a omission_n which_o have_v be_v the_o perfidious_a course_n of_o author_n in_o this_o case_n full_o and_o true_o enumerate_v the_o sensible_a and_o certain_a effect_n of_o opium_n in_o humane_a body_n and_o thereby_o empanneled_a a_o just_a jury_n for_o the_o trial_n of_o hypothesise_n which_o must_v be_v judge_v by_o the_o effect_n or_o phenomena_n of_o opium_n i_o will_v now_o proceed_v to_o their_o examination_n but_o because_o it_o will_v be_v endless_a to_o take_v every_o one_o particular_o into_o consideration_n i_o will_v use_v their_o stratagem_n who_o blow_v up_o foundation_n to_o save_v the_o tedious_a peck_v at_o all_o the_o part_n of_o the_o superstructure_n which_o in_o this_o case_n will_v require_v a_o age_n and_o take_v up_o all_o my_o time_n in_o demolish_n they_o which_o may_v be_v better_o employ_v in_o erect_v something_o that_o may_v be_v useful_a i_o have_v consider_v and_o find_v that_o the_o foundation_n in_o which_o all_o author_n both_o ancient_a and_o modern_a agree_v and_o whereupon_o they_o have_v hitherto_o endeavour_v to_o build_v look_v upon_o it_o as_o firm_a and_o warrantable_a in_o all_o age_n be_v this_o viz._n that_o opium_n operate_v by_o diminish_v or_o disable_n the_o spirit_n mean_v the_o animal_n spirit_n the_o ancient_n affirm_v that_o it_o do_v so_o by_o a_o extreme_a cold_a quality_n etc._n etc._n and_o the_o modern_n who_o observe_v it_o to_o act_n while_o it_o be_v at_o stomach_n by_o affect_v the_o brain_n nerve_n animal_n spirit_n etc._n etc._n and_o conclude_v no_o action_n be_v perform_v without_o contact_n infer_v and_o agree_v because_o no_o visible_a passage_n can_v be_v find_v from_o the_o stomach_n to_o the_o head_n that_o it_o must_v of_o absolute_a necessity_n act_v by_o fume_n vapour_n auras_fw-la or_o effluvium_n send_v up_o out_o of_o the_o stomach_n to_o the_o brain_n nerve_n etc._n etc._n so_o that_o all_o the_o remain_a question_n among_o the_o modern_n be_v which_o way_n those_o fume_n or_o vapour_n do_v the_o feat_n all_o allow_v the_o fume_n do_v it_o one_o say_v that_o they_o stuff_v the_o pore_n of_o the_o brain_n and_o so_o hinder_v the_o generation_n of_o animal_n spirit_n a_o second_o that_o they_o constringed_a and_o close_v the_o pore_n together_o thereby_o hinder_v the_o say_a generation_n a_o three_o that_o they_o fix_v and_o coagulate_v the_o animal_n spirit_n as_o wedelius_n and_o other_o a_o four_o that_o they_o cloud_v the_o animal_n spirit_n a_o five_o that_o they_o act_v as_o a_o poison_n as_o willis_n and_o many_o other_o a_o six_o that_o they_o clog_v the_o animal_n spirit_n by_o adhere_v to_o they_o etc._n etc._n not_o know_v nor_o i_o think_v care_v what_o they_o say_v so_o they_o humour_a their_o own_o imagination_n and_o hypothesise_n though_o utter_o incapable_a of_o solve_v the_o effect_n of_o opium_n especial_o be_v most_o constant_a proper_a and_o genuine_a effect_n for_o how_o can_v a_o cold_a quality_n which_o opium_n never_o have_v cause_v a_o gay_a and_o brisk_a humour_n bravery_n magnanimity_n euphory_n in_o labour_n promptitude_n to_o venus_n etc._n etc._n and_o how_o can_v cloud_n of_o vapour_n hinder_v the_o generation_n of_o animal_n spirit_n by_o stuff_v or_o constr_v the_o pore_n of_o the_o brain_n poison_v fix_v coagulate_v clog_a or_o cloud_v the_o animal_n spirit_n cause_v a_o fine_a ovation_n thereof_o a_o gay_a brave_a courageous_a and_o magnanimous_a disposition_n euphory_n promptitude_n to_o venery_n serenity_n expediteness_n in_o management_n etc._n etc._n which_o be_v as_o have_v be_v say_v the_o constant_a and_o proper_a effect_n of_o opium_n nor_o indeed_o be_v any_o of_o those_o author_n so_o foolhardy_a as_o to_o attempt_v it_o
good_a humour_a of_o which_o he_o be_v seldom_o capable_a and_o utter_o incapable_a of_o all_o or_o most_o of_o the_o other_o brisk_a effect_n as_o euphory_n promptitude_n to_o venus_n exertion_n of_o courage_n etc._n etc._n it_o be_v either_o pass_v by_o as_o a_o ordinary_a thing_n of_o course_n and_o so_o not_o heed_v or_o else_o impute_v to_o refreshment_n by_o sleep_n ease_n from_o pain_n or_o some_o amendment_n as_o to_o the_o disease_n or_o indeed_o to_o any_o thing_n rather_o than_o dispiriting_n and_o stupify_a opium_n that_o be_v so_o far_o in_o all_o opinion_n from_o exciting_a the_o spirit_n that_o all_o affirm_v conclude_v and_o agree_v that_o it_o diminish_v or_o disable_v they_o the_o like_a be_v to_o be_v say_v of_o any_o of_o the_o lively_a effect_n in_o case_n they_o happen_v and_o be_v observe_v though_o i_o do_v not_o see_v how_o they_o can_v so_o at_o least_o as_o any_o slander_n by_o will_v refer_v it_o to_o opium_n beside_o that_o as_o to_o some_o of_o the_o brisk_a effect_n especial_o that_o of_o venery_n great_a dose_n be_v requisite_a to_o render_v it_o any_o thing_n remarkable_a than_o be_v use_v in_o these_o western_a part_n and_o that_o modesty_n will_v much_o hinder_v the_o discovery_n of_o this_o effect_n be_v it_o not_o therefore_o very_o manifest_a that_o i_o have_v great_a cause_n to_o suspect_v that_o both_o ancient_n and_o modern_a physician_n consider_v thing_n by_o half_n since_o they_o do_v not_o take_v the_o most_o genuine_a property_n into_o their_o consideration_n and_o that_o they_o lay_v their_o foundation_n upon_o the_o most_o contrary_a effect_n to_o they_o it_o follow_v then_o that_o the_o general_a supposition_n of_o all_o the_o learned_a can_v no_o more_o solve_v the_o true_a property_n of_o opium_n in_o any_o probability_n than_o give_v the_o reason_n why_o fire_n harden_v clay_n can_v explain_v why_o it_o soften_v wax_n the_o reason_n do_v i_o say_v i_o shall_v have_v say_v than_o give_v the_o wrong_a reason_n why_o it_o harden_v clay_n show_v how_o it_o soften_v wax_n for_o it_o will_v appear_v in_o the_o follow_a chapter_n that_o they_o give_v no_o right_a reason_n for_o any_o effect_n of_o opium_n even_o those_o they_o ever_o allow_v to_o be_v its_o effect_n nor_o lay_v any_o true_a foundation_n to_o explain_v the_o least_o mean_a and_o plain_a effect_n thereof_o forasmuch_o as_o all_o their_o supposition_n be_v so_o false_a that_o there_o never_o be_v any_o such_o thing_n as_o they_o lie_v down_o to_o explain_v the_o effect_n of_o opium_n viz._n 1._o no_o such_o thing_n as_o a_o cold_a quality_n in_o opium_n 2._o no_o such_o thing_n as_o fume_n etc._n etc._n fly_v from_o opium_n to_o the_o brain_n while_o it_o be_v at_o stomach_n 3._o no_o such_o thing_n as_o diminish_v or_o disable_n the_o animal_n spirit_n by_o opium_n any_o way_n whatsoever_o of_o which_o in_o their_o order_n in_o the_o follow_a chapter_n chap._n ix_o it_o be_v prove_v that_o opium_n have_v no_o cold_a quality_n to_o diminish_v or_o disable_v the_o spirit_n thereby_o have_v show_v just_a cause_n of_o my_o suspicion_n of_o that_o universal_a foundation_n of_o opium_n diminish_v or_o disable_n the_o spirit_n i_o will_v now_o proceed_v to_o a_o more_o strict_a examination_n thereof_o beginning_n with_o the_o opinion_n of_o the_o ancient_n who_o affirm_v that_o opium_n diminish_v or_o disable_v the_o spirit_n by_o a_o extreme_a cold_a quality_n i_o confess_v that_o much_o may_v be_v do_v towards_o the_o diminish_n or_o disable_n the_o spirit_n by_o opium_n if_o it_o have_v such_o a_o cold_a quality_n as_o the_o ancient_n attribute_v to_o it_o for_o than_o it_o must_v be_v such_o a_o coldness_n as_o the_o cold_a thing_n either_o actual_a or_o potential_a bear_v no_o proportion_n to_o for_o ice_n snow_n etc._n etc._n bear_v no_o proportion_n to_o it_o in_o cause_v the_o same_o effect_n by_o a_o cold_a quality_n it_o be_v the_o manner_n of_o the_o ancient_n implicit_o to_o believe_v and_o subscribe_v to_o what_o their_o great_a author_n and_o master_n in_o physic_n or_o philosophy_n teach_v they_o who_o they_o adore_v as_o infallible_a god_n as_o soon_o as_o their_o mortality_n prove_v the_o contrary_a which_o be_v as_o absurd_a as_o assert_v tha_z opium_n which_o be_v one_o of_o the_o hot_a thing_n that_o vegetable_n afford_v be_v extreme_a cold_a bless_a be_v god_n for_o our_o light_n in_o religion_n and_o liberty_n in_o philosophy_n therefore_o some_o such_o admire_a author_n or_o great_a master_n in_o physic_n have_v assert_v that_o opium_n act_v by_o a_o extreme_a cold_a quality_n all_o do_v implicit_o subscribe_v to_o it_o the_o devil_n who_o they_o worship_v can_v not_o though_o a_o deceiver_n from_o the_o beginning_n impose_v more_o upon_o their_o faith_n than_o in_o cause_v they_o for_o i_o can_v think_v but_o it_o be_v some_o such_o evil_a power_n to_o believe_v that_o opium_n be_v cold_a against_o all_o the_o evidence_n of_o sense_n and_o experience_n he_o may_v have_v as_o well_o tell_v they_o that_o hell_n fire_n have_v all_o the_o property_n of_o common_a culinary_a fire_n and_o yet_o nothing_o more_o refresh_v by_o its_o cold_a quality_n for_o as_o many_o of_o our_o sense_n as_o can_v take_v notice_n of_o heat_n and_o cold_a do_v plain_o inform_v we_o that_o it_o be_v very_o hot_a in_o itself_o and_o effect_n for_o 1._o it_o be_v taste_n be_v very_o bitter_a rank_a vehement_o hot_a burn_a and_o bite_v all_o which_o quality_n be_v infallible_a sign_n of_o great_a heat_n and_o the_o better_a the_o opium_n be_v the_o more_o intense_a be_v those_o quality_n nay_o it_o be_v observe_v that_o its_o very_a virtue_n be_v strict_o combine_v to_o or_o consist_v in_o those_o quality_n especial_o bitterness_n which_o if_o lose_v the_o virtue_n be_v go_v as_o be_v common_o observe_v and_o easy_o observable_a it_o be_v a_o wise_a fetch_v of_o amatus_fw-la lusitanus_n in_o defence_n of_o its_o cold_a quality_n to_o attribute_v all_o its_o bitterness_n to_o glaucium_fw-la that_o be_v mix_v therewith_o whereas_o glaucium_fw-la always_o give_v a_o yellow_a tincture_n to_o water_n and_o opium_n a_o red_a but_o the_o opium_n that_o give_v no_o yellow_a tincture_n be_v bitter_a also_o yea_o that_o be_v most_o bitter_a that_o give_v the_o red_a tincture_n how_o come_v theban_a opium_n and_o indeed_o all_o other_o opium_n to_o be_v bitter_a before_o any_o thing_n be_v mix_v with_o it_o how_o inadvertent_o absurd_a people_n will_v be_v to_o defend_v absurdity_n it_o be_v pretty_a to_o see_v how_o they_o will_v expose_v themselves_o to_o defend_v a_o false_a opinion_n 2._o it_o be_v smell_n which_o be_v very_a rank_n strong_a hot_a and_o such_o as_o thing_n high_o impregnate_v with_o volatile_a salt_n and_o sulphur_n the_o two_o hot_a principle_n in_o nature_n do_v afford_v it_o be_v from_o volatile_a salt_n that_o cantharides_n pismire_n spear-wort_n crowsfoot_n etc._n etc._n be_v so_o very_o hot_a as_o to_o blister_v or_o exulcerate_v and_o be_v not_o all_o hot_a spirit_n such_o upon_o the_o account_n of_o their_o sulphur_n as_o spirit_n of_o wine_n brandy_n etc._n etc._n 3._o the_o best_a and_o strong_a opium_n will_v also_o exulcerate_v as_o all_o author_n agree_v which_o only_a fire_n or_o such_o thing_n as_o have_v the_o particle_n of_o fire_n lodge_v in_o they_o as_o lixiviate_n etc._n etc._n or_o the_o hot_a thing_n in_o nature_n will_v do_v as_o cantharides_n spear-wort_n etc._n etc._n it_o be_v 4._o for_o the_o like_a reason_n a_o psilothrick_n or_o causer_n of_o hair_n to_o fall_v which_o only_a lime_n orpâ—ment_n and_o the_o hot_a thing_n do_v cause_n 5._o it_o be_v inflammable_a which_o only_o sulphurecus_fw-la thing_n be_v 6._o it_o cause_v a_o sense_n of_o a_o vehement_a heat_n at_o stomach_n though_o take_v but_o in_o the_o quantity_n of_o a_o drachm_n 7._o it_o cause_v dryness_n of_o the_o mouth_n and_o thirst_v though_o take_v but_o in_o the_o quantity_n of_o 3_o grain_n which_o nothing_o do_v but_o hot_a thing_n 8._o it_o discuss_n and_o all_o discusser_n be_v hot_a for_o it_o be_v by_o heat_n that_o they_o do_v discuss_v as_o spirit_n of_o wine_n cummin-seed_n volatile_a salt_n and_o all_o hot_a spirit_n 9_o it_o soon_o operate_v and_o in_o a_o small_a quantity_n which_o be_v a_o infallible_a proof_n of_o the_o activity_n of_o its_o part_n which_o argue_v heat_n not_o cold._a 10._o it_o cause_v a_o gay_a pleasant_a and_o merry_a humour_n which_o only_a wine_n and_o hot_a liquor_n etc._n etc._n do_v and_o one_o grain_n of_o opium_n will_v cause_v they_o as_o much_o as_o several_a glass_n of_o wine_n which_o argue_v that_o its_o heat_n be_v much_o great_a 11._o i_o will_v fain_o know_v how_o or_o see_v any_o instance_n of_o any_o cold_a thing_n raise_v the_o spirit_n cause_v courage_n magnanimity_n enable_v people_n to_o labour_n journey_n etc._n
watch_n and_o sentinel_n to_o discover_v and_o give_v notice_n of_o what_o be_v or_o be_v not_o good_a and_o agreeable_a to_o our_o animal_n nature_n that_o upon_o notice_n of_o what_o be_v good_a and_o agreeable_a pleasure_n comfort_n satisfaction_n etc._n etc._n be_v conceive_v otherwise_o displeasure_n discomfort_n and_o dissatisfaction_n what_o diminish_v or_o disable_v our_o spirit_n do_v we_o the_o great_a evil_n that_o can_v be_v and_o consequent_o sensation_n will_v according_a to_o its_o office_n give_v we_o such_o notice_n thereof_o as_o will_v cause_v displeasure_n etc._n etc._n otherwise_o these_o sentinel_n that_o god_n and_o nature_n have_v appoint_v for_o faithful_a notice_n will_v instead_o of_o trusty_a service_n which_o be_v the_o end_n they_o be_v make_v for_o deceive_v we_o and_o consequent_o do_v we_o mischief_n rather_o than_o good_a which_o be_v very_o profane_a if_o not_o blasphemous_a to_o assert_v as_o be_v high_o abusive_a of_o god_n goodness_n and_o wisdom_n to_o make_v thing_n in_o nature_n that_o will_v not_o only_o not_o answer_n but_o act_n quite_o contrary_a to_o their_o end_n it_o follow_v then_o that_o what_o cause_v such_o a_o mighty_a agreeable_a and_o pleasant_a sensation_n at_o stomach_n which_o be_v the_o great_a and_o most_o accurate_a judge_n of_o what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n can_v be_v destructive_a or_o disable_n of_o its_o spirit_n which_o be_v the_o most_o excellent_a and_o useful_a thing_n that_o belong_v thereto_o therefore_o opium_n which_o so_o mighty_o recommend_v itself_o to_o please_v and_o comfort_v the_o great_a judge_n that_o god_n have_v give_v to_o a_o sensible_a creature_n to_o discern_v what_o be_v good_a and_o evil_a for_o it_o can_v diminish_v or_o disable_v our_o spirit_n one_o may_v say_v what_o i_o dare_v not_o that_o the_o sensation_n at_o stomach_n may_v deceive_v we_o we_o may_v deceive_v ourselves_o and_o say_v so_o when_o that_o which_o please_v the_o stomach_n do_v not_o please_v our_o pervert_v imagination_n which_o make_v no_o argument_n let_v we_o therefore_o consider_v thing_n where_o there_o be_v no_o such_o vain_a imagination_n to_o contradict_v the_o good_a end_n of_o nature_n if_o the_o stomach_n and_o sense_n in_o a_o brute_n or_o mere_a animal_n which_o have_v no_o other_o mean_n to_o judge_n of_o what_o be_v good_a or_o evil_n for_o it_o shall_v not_o judge_v aright_o all_o the_o animal_n in_o the_o whole_a world_n will_v soon_o perish_v it_o be_v the_o vain_a opinion_n of_o man_n that_o persuade_v they_o that_o thing_n be_v cold_a when_o hot_a etc._n etc._n as_o in_o the_o case_n of_o opium_n when_o the_o sense_n true_o inform_v that_o it_o be_v hot_a if_o you_o will_v stand_v to_o your_o imagination_n and_o supposition_n for_o such_o all_o must_v be_v without_o the_o information_n of_o sense_n against_o the_o dictate_v of_o sensation_n you_o must_v inevitable_o err_v but_o one_o may_v say_v be_v the_o sense_n at_o stomach_n such_o a_o infallible_a guide_n always_o i_o believe_v it_o will_v be_v very_o hard_a to_o give_v many_o instance_n to_o the_o contrary_a and_o prove_v it_o well_o however_o if_o we_o do_v or_o may_v allow_v something_o of_o this_o kind_a to_o a_o pervert_v stomach_n at_o certain_a time_n to_o avoid_v a_o squabble_n about_o it_o it_o be_v never_o to_o be_v allow_v that_o all_o the_o stomach_n in_o the_o whole_a world_n shall_v be_v please_v with_o one_o and_o the_o same_o thing_n at_o all_o time_n and_o yet_o that_o this_o thing_n shall_v be_v so_o high_o pernicious_a to_o the_o animal_n as_o to_o diminish_v or_o disable_v its_o spirit_n then_o indeed_o it_o will_v follow_v that_o the_o most_o exquisite_a sense_n at_o stomach_n to_o discern_v what_o be_v or_o be_v not_o agreeable_a to_o the_o animal_n be_v absolute_o in_o vain_a which_o no_o man_n of_o reason_n that_o have_v any_o apprehension_n of_o the_o wisdom_n of_o god_n and_o nature_n can_v assert_v 3._o what_o be_v more_o notorious_a than_o that_o pleasure_n or_o be_v please_v raise_v and_o displeasure_n or_o be_v grieve_v depress_n the_o spirit_n be_v not_o all_o people_n pleasant_a gay_a and_o good_a humour_a brisk_a prompt_a etc._n etc._n when_o please_v do_v not_o man_n travel_v or_o labour_n with_o more_o ease_n in_o pleasant_a company_n etc._n etc._n but_o of_o these_o matter_n and_o the_o reason_n thereof_o more_o in_o the_o follow_a chapter_n 4._o how_o can_v opium_n that_o revive_v people_n when_o they_o be_v so_o dispirited_a that_o they_o be_v even_o almost_o die_v as_o when_o opium_n be_v want_v by_o such_o as_o use_v to_o take_v it_o in_o deliquiâ—ms_n and_o agony_n from_o paiâ—_n etc._n etc._n diminish_v or_o disable_v the_o spirit_n it_o be_v plain_a contradiction_n to_o say_v that_o it_o shall_v next_o to_o opium_n nothing_o revive_v people_n in_o such_o case_n better_o than_o wine_n and_o those_o thing_n that_o produce_v the_o same_o or_o like_a effect_n have_v like_o nature_n and_o who_o can_v say_v that_o wine_n that_o be_v make_v to_o glad_a the_o heart_n of_o man_n diminish_v or_o disable_v the_o spirit_n or_o that_o opium_n which_o produce_v all_o the_o sprightly_a enliven_a and_o encourage_v effect_n of_o generous_a wine_n in_o a_o more_o eminent_a manner_n than_o wine_n and_o in_o the_o 10000th_o part_n of_o its_o quantity_n and_o for_o a_o long_a time_n than_o wine_n cause_v they_o shall_v diminish_v or_o disable_v the_o spirit_n for_o instance_n wine_n and_o opium_n in_o a_o due_a quantity_n but_o opium_n in_o a_o far_o less_o quantity_n as_o be_v say_v cause_v a_o pleasant_a gay_a and_o good_a humour_n courage_n bravery_n magnanimity_n promptitude_n in_o business_n expediteness_n in_o management_n serenity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n fatigue_n etc._n etc._n both_o take_v away_o sadness_n grief_n melancholy_n fear_v depression_n of_o spirit_n etc._n etc._n both_o cause_n promptitude_n to_o venery_n sine_fw-la cerere_fw-la &_o baccho_fw-la friget_fw-la venus_n so_o wine_n and_o opium_n prevent_v and_o cure_v cold_a open_v the_o pore_n promote_v perspiration_n and_o sweat_n especial_o the_o follow_a morning_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v of_o opium_n and_o be_v notorious_a as_o to_o wine_n both_o cause_n sleep_n and_o take_v away_o the_o sense_n of_o pain_n and_o require_v a_o great_a dose_n than_o ordinary_a in_o proportion_n to_o the_o pain_n both_o take_v off_o shivering_n from_o fear_n cold_a or_o ague_n fit_n and_o cause_n mirth_n contentation_n and_o acquiescence_n dryness_n of_o the_o mouth_n thirst_v a_o sense_n of_o heat_n within_o we_o a_o dream_v condition_n pleasant_a dream_n if_o the_o quantity_n of_o wine_n be_v not_o grievous_a by_o its_o heat_n load_n etc._n etc._n nocturnal_a pollution_n and_o in_o some_o constitution_n both_o cause_n vigilancy_n but_o wine_n and_o opium_n cause_v that_o more_o rare_o than_o sleep_n both_o stop_n and_o cause_n vomit_v if_o they_o stay_v too_o long_o at_o stomach_n both_o moderate_a hunger_n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d and_o be_v good_a in_o a_o canine_a appetite_n both_o cause_n swim_v in_o the_o head_n etc._n etc._n so_o both_o in_o a_o excessive_a do_v do_v cause_n at_o first_o mirth_n and_o afterward_o a_o kind_n of_o drunken_a soper_n in_o some_o in_o other_o fury_n or_o madness_n sardonick_a laughter_n and_o weight_n at_o stomach_n vomit_n hiccough_n great_a heat_n at_o stomach_n debility_n and_o laxity_n of_o all_o part_n falter_v of_o the_o tongue_n scotomy_n and_o darkness_n of_o the_o eye_n vertigo_n laxity_n of_o the_o cornea_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la deadness_n of_o the_o eye_n to_o the_o view_n loss_n of_o memory_n venereal_a fury_n a_o high_a colour_n profuse_a sweat_v purge_v sometime_o alienation_n of_o the_o mind_n loss_n of_o memory_n and_o last_o great_a or_o lesser_a effect_n according_a to_o the_o do_v constitution_n etc._n etc._n so_o a_o long_a and_o lavish_a use_n of_o both_o cause_n a_o dull_a and_o moapish_a disposition_n dropsy_n fall_v of_o humour_n upon_o weaken_v part_n a_o sleepy_a disposition_n want_v of_o appetite_n weakness_n of_o digestion_n aptitude_n to_o sterility_n and_o abortion_n early_a decrepiteness_n stoop_v in_o the_o back_n tremble_v of_o the_o hand_n weakness_n of_o memory_n shortness_n of_o life_n difficulty_n and_o danger_n in_o sudden_o leave_v they_o off_o revive_v such_o as_o sink_v for_o want_n of_o either_o and_o supply_v the_o want_n of_o each_o other_o how_o can_v any_o have_v the_o face_n to_o say_v that_o a_o thing_n which_o agree_v so_o with_o generous_a wine_n in_o effect_n can_v be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n the_o mischief_n of_o excessive_a dose_n and_o lavish_a use_n of_o either_o be_v no_o argument_n against_o their_o inspirit_a nature_n if_o it_o be_v than_o wine_n be_v no_o cordial_n though_o make_v to_o glad_a the_o heart_n
be_v the_o cause_n why_o p_o be_v a_o kind_n of_o shut_v f_o and_o f_o a_o kind_n of_o a_o open_a p_o for_o suppose_v p_o open_v at_o the_o round_a part_n to_o signify_v that_o the_o lip_n be_v not_o close_v in_o sound_a f_o and_o that_o the_o low_a stroke_n or_o part_n be_v leave_v short_a to_o signify_v that_o the_o low_a lip_n be_v draw_v inward_a in_o sound_v f_o the_o p_o become_v a_o perfect_a f._n the_o reason_n why_o the_o opium_n that_o come_v from_o thebes_n now_o call_v thief_n be_v and_o be_v the_o best_a be_v 1._o that_o thebes_n or_o thief_n be_v in_o egypt_n lie_v in_o a_o hot_a country_n that_o be_v near_o the_o line_n or_o equator_fw-la than_o any_o of_o the_o country_n on_o the_o north-side_n of_o the_o mediterranean_a for_o it_o be_v observe_v that_o the_o heat_n of_o climate_n contribute_v very_o much_o to_o the_o strength_n of_o opium_n which_o be_v weak_a if_o you_o make_v it_o in_o england_n or_o germany_n than_o in_o france_n in_o the_o northern_a part_n of_o france_n than_o in_o languedoc_n which_o border_n upon_o the_o mediterranean_a and_o weak_a there_o than_o in_o smirna_n anatolia_n aleppo_n and_o apulia_n which_o be_v more_o southern_a and_o weak_a in_o those_o place_n than_o in_o thebais_n in_o egypt_n for_o which_o cause_n we_o may_v judge_v that_o the_o opium_n which_o come_v to_o england_n from_o the_o east-indies_n that_o be_v yet_o hot_a than_o egypt_n be_v much_o worse_a than_o that_o of_o thebes_n or_o thief_n must_v in_o all_o probability_n be_v adulterate_v or_o make_v of_o the_o leave_n and_o stem_n of_o the_o poppy_n as_o some_o say_v otherwise_o it_o will_v be_v rather_o better_v as_o come_v from_o the_o hot_a country_n 2._o that_o of_o thebes_n may_v be_v better_o because_o the_o heat_n of_o egypt_n be_v more_o constant_a and_o uniform_a than_o in_o anatolia_n aleppo_n smirna_n etc._n etc._n the_o quantity_n of_o opium_n which_o be_v gather_v by_o the_o milky_a juice_n of_o the_o poppy_n head_n drop_v into_o shell_n out_o of_o the_o incision_n aforesaid_a be_v but_o small_a and_o the_o use_v of_o this_o most_o noble_a please_a and_o generous_a of_o cordial_n and_o medicament_n daily_o increase_v by_o the_o constant_a and_o insallible_a benefit_n they_o find_v thereby_o man_n partly_o to_o avoid_v the_o tediousness_n of_o gather_v it_o by_o drop_n and_o partly_o out_o of_o necessity_n but_o main_o it_o be_v to_o be_v doubt_v out_o of_o covetousness_n begin_v to_o bruise_v and_o pound_n the_o poppy_n head_n and_o to_o squeeze_v out_o the_o juice_n for_o expedition_n and_o quantitic_n sake_n which_o bruise_v and_o squeese_v cause_v it_o to_o look_v blackish_a this_o the_o greek_n for_o distinction_n sake_n call_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d from_o the_o word_n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d which_o signify_v poppy_n still_o call_v the_o better_a sort_n which_o be_v gather_v in_o shell_n out_o of_o the_o incision_n of_o the_o poppy_n head_n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d thus_o have_v you_o the_o true_a original_a of_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d and_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d which_o the_o latin_n and_o we_o from_o they_o call_v opium_n and_o meconium_n though_o as_o it_o happen_v in_o most_o thing_n in_o merchandise_n to_o recommend_v the_o good_n we_o now_o call_v the_o meconium_n opium_n by_o the_o better_a name_n as_o they_o do_v in_o another_o case_n out_o of_o abundance_n of_o absurd_a civility_n call_v every_o quack_n a_o doctor_n afterward_o its_o use_n grow_v more_o and_o more_o they_o add_v the_o leave_n to_o the_o poppy_n head_n in_o the_o pound_v bruise_a and_o express_v the_o juice_n boil_v it_o for_o speed_n sake_n to_o the_o consistence_n of_o a_o confection_n which_o cool_v come_v to_o the_o consistence_n that_o we_o have_v it_o in_o i_o mean_v the_o fresh_a and_o soft_a sort_n that_o we_o have_v which_o by_o the_o forcible_a pound_v squeeze_v and_o boil_a contract_v a_o blackish_a colour_n like_o that_o of_o horse-aloe_n on_o the_o outside_n to_o which_o colour_n the_o air_n do_v very_o much_o contribute_v and_o press_v the_o superficies_n close_o together_o for_o if_o you_o rude_o tear_v a_o piece_n of_o that_o we_o have_v which_o be_v all_o of_o this_o last_o kind_n it_o look_v at_o first_o as_o be_v say_v of_o a_o red_a yellow_a but_o the_o air_n especial_o if_o moist_a or_o any_o moisture_n and_o handle_v of_o it_o and_o close_v the_o superficies_n together_o soon_o make_v it_o look_v blackish_a again_o this_o as_o be_v intimate_v be_v that_o we_o now_o call_v opium_n and_o have_v in_o common_a use._n which_o be_v also_o in_o common_a use_n among_o the_o grecian_n when_o the_o turk_n conquer_a they_o be_v by_o the_o grecian_n themselves_o call_v pous_a or_o pos_n with_o the_o o_o mouth_v wide_o which_o come_v doubtless_o from_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d the_o meconium_n at_o last_o gain_v the_o better_a name_n of_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d or_o pous_a or_o pos_n after_o the_o manner_n aforesaid_a to_o recommend_v it_o as_o all_o opium_n be_v now_o call_v theban_n and_o the_o o_o in_o the_o begin_n of_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d pass_v over_o in_o the_o run_v of_o discourse_n which_o be_v not_o uncommon_a with_o vowel_n because_o of_o their_o flat_a sound_n which_o be_v so_o by_o reason_n of_o the_o wide_a passage_n that_o the_o breath_n have_v between_o the_o tongue_n and_o the_o palate_n in_o the_o formation_n thereof_o for_o wideness_n of_o passage_n be_v the_o cause_n of_o flatness_n as_o narrowness_n in_o bird_n child_n etc._n etc._n be_v the_o cause_n of_o sharpness_n of_o sound_n therefore_o the_o sound_n of_o vowel_n be_v flat_a fade_a and_o consequent_o not_o as_o much_o miss_v as_o sharp_a sound_n we_o often_o omit_v vowel_n particular_o in_o the_o begin_n of_o word_n for_o ease_n and_o shortness_n sake_n thus_o it_o come_v to_o pass_v that_o man_n say_v apothecary_n for_o apothecary_n that_o man_n say_v apprentice_n for_o apprentice_n that_o man_n say_v buttal_n for_o abuttal_n that_o man_n say_v alarm_n for_o alarm_n that_o man_n say_v light_a for_o alight_v that_o man_n say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d or_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d for_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d and_o as_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d come_v to_o be_v sound_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d so_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d as_o natural_o to_o be_v sound_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d or_o pous_a because_o it_o be_v easy_a to_o sound_v u._fw-mi after_o o_o in_o this_o and_o some_o other_o case_n than_o to_o omit_v it_o as_o it_o be_v easy_a to_o sound_v p_o between_o m_o and_o t_o etc._n etc._n than_o not_o as_o in_o tempt_v crump_a limpt_v etc._n etc._n which_o be_v more_o easy_o so_o sound_v than_o if_o the_o sound_n of_o p_o be_v leave_v out_o which_o i_o call_v easmess_n of_o consequence_n hence_o it_o be_v that_o bold_a be_v sound_v bould_n that_o sold_n be_v sound_v sould._n that_o hold_v be_v sound_v hould_n that_o bolt_n be_v sound_v bolt_o that_o jowl_n be_v sound_v joul_n that_o toll_n etc._n etc._n be_v sound_v toul_n etc._n etc._n change_a the_o o_o into_o ou_fw-fr as_o the_o grecian_n do_v pos_n to_o pous_a for_o this_o and_o such_o reason_n it_o be_v that_o the_o national_a greek_n can_v hardly_o be_v understand_v by_o scholar_n when_o speak_v by_o the_o native_n it_o be_v for_o the_o same_o reason_n that_o the_o greek_n write_v greek_a as_o we_o do_v english_a and_o the_o french_a do_v their_o language_n different_a from_o what_o they_o speak_v so_o that_o if_o any_o man_n shall_v learn_v french_a or_o english_a and_o always_o sound_v it_o as_o it_o be_v write_v or_o print_v he_o will_v very_o hardly_o understand_v they_o as_o they_o be_v vulgar_o speak_v which_o be_v the_o very_a case_n of_o such_o as_o learn_v greek_a by_o book_n who_o always_o sound_v every_o letter_n whereas_o the_o native_a greek_n do_v what_o all_o nation_n do_v more_o or_o less_o shorten_v and_o alter_v the_o sound_n of_o word_n in_o the_o common_a run_n of_o discourse_n by_o a_o natural_a propensity_n unto_o and_o pursuit_n of_o ease_n pleasure_n and_o speed_v which_o by_o degree_n very_o much_o alter_v the_o sound_n of_o word_n the_o turk_n have_v be_v use_v to_o call_v the_o better_a sort_n that_o drop_v out_o of_o the_o incision_n make_v in_o the_o poppy_n head_n maslack_n continue_v that_o name_n to_o that_o sort_n after_o they_o conquer_a greece_n and_o call_v the_o other_o sorf_n which_o they_o find_v in_o use_n among_o the_o grecian_n by_o the_o name_n that_o the_o grecian_n give_v it_o viz._n pous_a and_o such_o as_o common_o use_v it_o they_o call_v pousti_n by_o way_n of_o contempt_n as_o if_o we_o shall_v say_v small_a beer-drinker_n in_o comparison_n
why_o then_o do_v they_o write_v and_o trouble_v the_o world_n to_o peruse_v their_o book_n when_o they_o be_v so_o far_o from_o explain_v the_o property_n of_o opium_n that_o they_o scarce_o ever_o dare_v mention_v they_o nor_o set_v their_o hypothesise_n and_o they_o as_o much_o as_o in_o view_n of_o one_o another_o be_v not_o this_o a_o tacit_n confession_n of_o the_o incompetency_n of_o their_o supposition_n i_o beg_v pardon_n for_o call_v they_o they_o though_o they_o themselves_o do_v for_o i_o can_v offer_v they_o a_o great_a abuse_n than_o lay_v their_o spurious_a and_o lame_a brat_n at_o their_o door_n though_o one_o scarce_o need_v say_v any_o more_o of_o they_o yet_o lest_o i_o be_v think_v presumptuous_a or_o saucy_a for_o so_o much_o as_o offer_v to_o suspect_v the_o general_a foundation_n of_o all_o the_o famous_a author_n that_o ever_o live_v as_o galen_n avicenna_n etc._n etc._n among_o the_o ancient_n etmuller_n willis_n etc._n etc._n among_o the_o modern_n 1._o i_o will_v show_v you_o very_o just_a cause_n to_o suspect_v the_o insufficiency_n of_o the_o general_a foundation_n viz._n that_o opium_n diminish_v or_o disable_v the_o spirit_n 2._o i_o will_v prove_v that_o it_o do_v not_o do_v it_o by_o a_o cold_a quality_n 3._o that_o it_o do_v not_o do_v it_o by_o vapour_n fume_n aura_n or_o any_o such_o way_n 4._o that_o it_o diminish_v or_o disable_v the_o spirit_n by_o no_o mean_n whatsoever_o which_o diminish_v or_o disable_n of_o the_o spirit_n cold_a quality_n and_o fume_n or_o aura_n comprehend_v the_o foundation_n of_o all_o opinion_n concern_v opium_n that_o ever_o i_o read_v or_o hear_v of_o and_o consequent_o if_o those_o two_o fundamental_a opinion_n be_v refute_v all_o the_o superstructure_n that_o have_v be_v in_o this_o case_n must_v fall_v to_o the_o ground_n chap._n viii_o the_o author_n show_v just_a cause_n of_o his_o suspicion_n that_o all_o author_n have_v go_v upon_o a_o wrong_a foundation_n in_o their_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n i_o have_v show_v you_o that_o the_o general_a foundation_n of_o both_o ancient_n and_o modern_a author_n be_v that_o opium_n do_v diminish_v or_o disable_v the_o spirit_n and_o now_o i_o will_v plain_o show_v just_a cause_n of_o my_o suspicion_n of_o its_o insufficiency_n which_o be_v these_o 1._o i_o observe_v that_o all_o learned_a man_n be_v to_o this_o day_n high_o dissatisfy_v as_o to_o the_o cause_n and_o manner_n of_o the_o operation_n of_o opium_n notwithstanding_o all_o that_o have_v be_v write_v concern_v it_o and_o that_o it_o be_v the_o common_a cry_n on_o all_o hand_n that_o none_o have_v illustrate_v the_o operation_n of_o opium_n to_o any_o purpose_n or_o give_v any_o satisfaction_n therein_o and_o therefore_o learned_a physician_n be_v still_o as_o much_o upon_o the_o enquiry_n as_o ever_o they_o be_v it_o be_v much_o more_o civil_a and_o reasonable_a to_o suspect_v the_o foundation_n that_o all_o former_a author_n have_v build_v upon_o than_o a_o general_a failure_n in_o all_o the_o most_o judicious_a master_n builder_n that_o ever_o endeavour_v to_o build_v thereon_o for_o if_o all_o the_o best_a architect_n of_o the_o whole_a world_n fail_v to_o erect_v a_o firm_a superstructure_n upon_o any_o one_o foundation_n what_o can_v we_o think_v but_o that_o the_o foundation_n be_v infirm_a especial_o when_o as_o in_o our_o case_n no_o way_n that_o care_n judgement_n perspicacity_n and_o wit_n can_v invent_v or_o think_v of_o have_v be_v leave_v untried_a to_o build_v thereon_o so_o that_o though_o i_o modest_o call_v it_o a_o cause_n of_o suspicion_n it_o amount_v almost_o if_o not_o altogether_o to_o a_o demonstration_n that_o the_o foundation_n that_o all_o author_n have_v go_v upon_o be_v naught_o will_v not_o any_o consider_a man_n when_o he_o see_v all_o the_o judicious_a architect_n of_o the_o world_n fail_v to_o erect_v a_o firm_a building_n upon_o a_o certain_a foandation_n seek_v for_o another_o therefore_o who_o can_v blame_v i_o if_o i_o do_v and_o not_o blame_v they_o that_o do_v not_o the_o mean_a bricklayer_n or_o carpenter_n that_o shall_v be_v guilty_a of_o such_o stupidity_n as_o to_o attempt_v to_o build_v upon_o such_o a_o foundation_n as_o always_o deceive_v the_o builder_n will_v be_v think_v too_o great_a a_o blockhead_n to_o be_v employ_v in_o building_n 2._o i_o observe_v that_o most_o man_n do_v notwithstanding_o that_o foundation_n be_v agree_v upon_o think_v it_o impossible_a to_o explain_v the_o intricate_a various_a contradictory_n phenomena_n and_o mysterious_a effect_n of_o opium_n sit_v content_v and_o persuade_v that_o it_o operate_v by_o a_o occult_a quality_n whole_o unexplicable_a and_o particular_o reserve_v from_o the_o knowledge_n of_o mankind_n but_o nature_n work_v mechanical_o in_o weight_n measure_n etc._n etc._n therefore_o it_o be_v more_o than_o probable_a that_o it_o be_v only_o their_o be_v upon_o a_o wrong_a bottom_n make_v it_o seem_v absolute_o occult_a for_o it_o be_v impossible_a to_o find_v a_o thing_n where_o it_o be_v not_o or_o to_o build_v firm_o upon_o a_o insufficient_a foundation_n whereas_o have_v it_o be_v right_o and_o true_a it_o be_v not_o to_o be_v imagine_v but_o some_o or_o other_o will_v have_v thereupon_o do_v something_o that_o will_v have_v stand_v against_o all_o wind_n and_o storm_n which_o none_o have_v do_v 3._o i_o observe_v that_o none_o dare_v venture_v to_o lay_v the_o whole_a no_o nor_o one_o half_a of_o the_o burden_n of_o the_o phinomena_n or_o effect_n of_o opium_n upon_o that_o foundation_n foresee_v doubtless_o that_o it_o can_v not_o bear_v they_o and_o that_o if_o they_o lay_v any_o more_o weight_n thereon_o the_o whole_a will_v totter_v and_o fall_v to_o the_o ground_n the_o project_n in_o every_o hypothesis_n be_v to_o persuade_v man_n of_o the_o truth_n thereof_o and_o the_o only_a way_n to_o do_v it_o be_v to_o solve_v all_o phenomena_n thereby_o for_o if_o it_o fail_v but_o in_o one_o it_o be_v a_o infallible_a sign_n of_o its_o insufficiency_n there_o be_v no_o reason_n to_o omit_v any_o of_o the_o phenomena_n if_o they_o can_v have_v discern_v that_o the_o hypothesis_n will_v have_v bear_v they_o therefore_o as_o have_v be_v intimate_v it_o imply_v a_o confession_n of_o its_o incompetency_n 4._o i_o observe_v that_o ancient_a author_n write_v of_o opium_n before_o it_o come_v to_o be_v of_o common_a and_o general_a use_n in_o the_o daytime_n with_o healthy_a person_n as_o it_o since_o be_v in_o many_o nation_n to_o cause_v a_o gay_a pleasant_a and_o good_a humour_n take_v off_o sadness_n melancholy_a and_o anxiety_n to_o cause_n assurance_n boldness_n courage_n bravery_n magnanimity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n promptitude_n in_o business_n expediteness_n and_o serenity_n to_o excite_v to_o venery_n etc._n etc._n which_o effect_n can_v be_v explain_v by_o that_o supposition_n of_o disable_n the_o spirit_n and_o that_o they_o use_v opium_n only_a medicinally_n for_o the_o sake_n of_o such_o other_o effect_n as_o may_v be_v tolerable_o well_o explicate_v by_o that_o hypothesis_n so_o that_o they_o have_v not_o any_o occasion_n nor_o inducement_n to_o look_v any_o far_o the_o effect_n they_o give_v it_o for_o be_v only_o 1._o to_o cause_v sleep_n 2._o to_o take_v off_o pain_n 3._o to_o stop_v flux_n 4._o to_o compose_v the_o spirit_n 5._o to_o cause_v perspiration_n and_o sweat_n all_o which_o be_v not_o inconsistent_a with_o the_o hypothesis_n of_o diminish_v or_o disable_n the_o spirit_n as_o the_o other_o be_v and_o therefore_o may_v well_o deceive_v they_o for_o first_o sleep_n be_v cause_v by_o diminish_v the_o spirit_n by_o labour_n watch_v etc._n etc._n as_o be_v most_o notorious_a over_o the_o whole_a world_n so_o other_o thing_n that_o diminish_v the_o spirit_n as_o bleed_v vomit_v purge_v and_o many_o other_o cause_n of_o diminish_v thereof_o do_v incline_v we_o to_o sleep_v second_o indolence_n or_o exemption_n from_o pain_n be_v cause_v by_o nothing_o more_o than_o want_v of_o spirit_n as_o in_o paralytical_a case_n stuporâ—_n obstruction_n or_o compression_n of_o the_o nerve_n syncopes_fw-la leipothymy_n deliquium_n faint_n after_o bleed_v and_o sleep_v which_o as_o be_v say_v be_v so_o much_o cause_v by_o loss_n of_o spirit_n etc._n etc._n three_o flux_n be_v stop_v or_o moderate_v by_o nothing_o better_a than_o sleep_n which_o general_o as_o be_v say_v proceed_v from_o loss_n of_o spirit_n what_o also_o stop_v or_o moderate_v flux_n more_o than_o want_v of_o the_o sense_n of_o the_o irritation_n of_o humour_n and_o what_o take_v away_o sense_n more_o than_o want_v of_o spirit_n thus_o want_v of_o sense_n by_o the_o absence_n of_o the_o spirit_n in_o paralytical_a intestine_n stop_v flux_n thus_o fail_v a_o paralytical_a bladder_n to_o express_v the_o urine_n so_o a_o palsy_n of_o the_o membrane_n
impossible_a it_o shall_v be_v without_o such_o disturbance_n as_o i_o mention_v will_v follow_v if_o they_o pass_v in_o the_o road_n of_o the_o spirit_n it_o be_v not_o common_a sense_n that_o such_o câ—de_a blast_n shall_v meliorate_v or_o enliven_v the_o spirit_n to_o cause_v briskness_n bravery_n serenity_n courage_n magnanimity_n as_o opium_n do_v much_o less_o if_o those_o fume_n stop_v and_o crowd_v in_o the_o brain_n and_o any_o way_n hinder_v the_o generation_n of_o animal_n spirit_n as_o the_o common_a assertion_n be_v the_o like_a be_v to_o be_v say_v of_o their_o pass_v between_o the_o pia_fw-la mater_fw-la and_o the_o medullary_a part_n of_o the_o nerve_n which_o can_v be_v allow_v because_o of_o its_o close_a adherence_n thereto_o with_o this_o addition_n that_o they_o will_v constant_o cause_v a_o violent_a headache_n which_o opium_n and_o meal_n to_o which_o fume_n be_v particular_o attribute_v do_v often_o cure_v so_o if_o they_o get_v up_o to_o the_o head_n between_o the_o pia_n and_o dura_n mater_n it_o be_v headache_n and_o not_o the_o symptom_n of_o opium_n that_o they_o will_v produce_v which_o headache_n as_o be_v say_v opium_n and_o meal_n do_v cure_v 21._o last_o if_o they_o pass_v by_o any_o mean_n quite_o on_o the_o outside_n of_o the_o nerve_n and_o their_o membrane_n viz._n the_o pia_n and_o dura_n mater_n then_o must_v they_o take_v their_o lodgement_n if_o within_o the_o skull_n between_o the_o dura_n mater_n and_o the_o skull_n and_o produce_v no_o other_o symptom_n but_o a_o headache_n which_o as_o be_v say_v opium_n and_o meal_n rather_o cure_v than_o produce_v and_o if_o without_o the_o skull_n it_o be_v quite_o beside_o the_o cushion_n and_o the_o vaporarian_n own_o intention_n for_o in_o all_o these_o last_o case_n they_o can_v not_o affect_v the_o animal_n spirit_n for_o good_a or_o evil_n many_o and_o very_o many_o thing_n may_v be_v add_v to_o show_v the_o impossibility_n inconvenience_n incoherence_n absurdity_n etc._n etc._n that_o attend_v the_o passage_n of_o the_o fume_n and_o vapour_n into_o the_o brain_n head_n etc._n etc._n 22._o i_o have_v forgotâ—_n mention_v the_o absurdity_n of_o its_o pass_v up_o at_o gullet_n and_o so_o to_o the_o head_n because_o i_o can_v not_o imagine_v that_o any_o one_o will_v be_v so_o beastly_a a_o animal_n as_o to_o belch_v up_o a_o argument_n of_o that_o kind_n consider_v our_o very_a sense_n tell_v we_o that_o what_o come_v up_o that_o way_n pass_v out_o at_o mouth_n or_o nostril_n and_o because_o if_o it_o be_v so_o the_o operation_n of_o opium_n etc._n etc._n will_v be_v in_o proportion_n to_o our_o belch_a which_o be_v ridiculous_a 23._o the_o great_a comfort_n of_o a_o cordial_n be_v at_o first_o or_o soon_o after_o it_o be_v take_v but_o if_o '_o its_o comfort_n be_v by_o fume_n or_o essluvia_n pass_v to_o the_o blood_n or_o any_o where_o beside_o the_o comfort_n will_v as_o their_o cause_n of_o fume_n do_v increase_v for_o a_o long_a time_n and_o be_v more_o after_o a_o good_a while_n than_o at_o first_o so_o 24._o if_o opium_n operate_v by_o fume_n while_o at_o stomach_n which_o must_v gradual_o increase_v continual_o how_o come_v opium_n to_o be_v at_o the_o height_n of_o its_o operation_n in_o a_o short_a time_n viz._n in_o about_o half_a a_o hour_n after_o it_o begin_v sensible_o to_o operate_v or_o a_o hour_n at_o far_a and_o not_o increase_v continual_o in_o its_o operation_n as_o their_o pretend_a cause_n the_o fume_n must_v do_v by_o continual_a steam_a 25._o if_o opium_n operate_v by_o send_v fume_n by_o passage_n etc._n etc._n from_o the_o stomach_n to_o the_o brain_n i_o shall_v think_v that_o when_o it_o have_v get_v out_o of_o the_o stomach_n as_o into_o the_o intestine_n lacteal_v vein_n etc._n etc._n there_o shall_v be_v a_o kind_n of_o interval_n of_o its_o operation_n which_o be_v never_o observe_v till_o it_o get_v into_o the_o blood_n again_o therefore_o it_o do_v not_o operate_v by_o fume_n for_o the_o pylorus_n be_v always_o shut_v but_o when_o somewhat_o be_v send_v downward_o which_o will_v hinder_v the_o mount_a of_o the_o vapour_n into_o the_o stomach_n in_o order_n to_o pass_v to_o the_o brain_n 26._o if_o vapour_n be_v the_o cause_n of_o sleep_n after_o meal_n than_o shall_v we_o be_v more_o sleepy_a two_o or_o three_o hour_n after_o meal_n because_o of_o the_o abundance_n of_o the_o fume_n that_o will_v be_v crowd_v into_o the_o brain_n by_o that_o time_n but_o we_o be_v more_o sleepy_a present_o after_o meal_n and_o if_o we_o indulge_v it_o but_o for_o a_o quarter_n of_o a_o hour_n we_o be_v refresh_v and_o far_o from_o sleepiness_n afterward_o though_o the_o fume_n if_o that_o hypothesis_n be_v true_a will_v be_v much_o more_o at_o brain_n two_o or_o three_o hour_n after_o the_o meal_n so_o it_o be_v in_o the_o case_n of_o wine_n if_o one_o take_v a_o short_a nap_n after_o some_o glass_n he_o may_v drink_v a_o great_a many_o afterward_o without_o be_v sleepy_a which_o plain_o prove_v that_o it_o be_v not_o the_o fume_n of_o the_o wine_n be_v the_o cause_n of_o the_o sleep_n because_o he_o be_v not_o at_o all_o sleepy_a when_o there_o must_v be_v more_o fume_n 27._o all_o allow_v that_o hot_a fume_n assault_v the_o brain_n cause_n frenzy_n if_o that_o be_v true_a than_o the_o fume_n of_o wine_n and_o opium_n which_o be_v both_o very_a hot_a must_v always_o do_v so_o but_o opium_n and_o wine_n also_o do_v often_o cause_v composure_n good_a humour_n sleep_v etc._n etc._n which_o be_v contrary_a to_o frenzy_n therefore_o they_o do_v not_o operate_v by_o fume_n 28._o if_o sleep_n say_v helmont_n the_o only_a man_n that_o i_o have_v read_v who_o be_v against_o vapour_n be_v cause_v by_o vapour_n ascend_v from_o the_o stomach_n to_o the_o head_n obstruct_v and_o intercept_n all_o the_o passage_n of_o sensation_n motion_n speech_n judgement_n etc._n etc._n as_o the_o school_n say_v than_o a_o disease_n will_v have_v be_v before_o the_o fall_n of_o adam_n because_o sleep_n will_v have_v be_v a_o disease_n that_o be_v a_o flatulent_a and_o vaporous_a palsy_n 29._o all_o allow_v vomitives_n and_o purger_n to_o operate_v by_o irritation_n or_o a_o grievous_a sensation_n of_o the_o membrane_n of_o the_o stomach_n why_o not_o wine_n cordial_n opium_n etc._n etc._n by_o a_o pleasant_a sensation_n cujus_fw-la est_fw-la dolour_n aut_fw-la gravamen_fw-la ejusdem_fw-la est_fw-la voluptas_fw-la and_o as_o a_o grievous_a sensation_n or_o pain_n cause_v melancholy_a depression_n of_o spirit_n fretfulness_n lassitude_n etc._n etc._n so_o a_o pleasant_a sensation_n cause_v comfort_n elevation_n of_o the_o spirit_n euphory_n etc._n etc._n but_o we_o have_v not_o clear_v the_o way_n sufficient_o for_o these_o matter_n yet_o which_o will_v in_o due_a time_n be_v solemn_o consider_v obj._n it_o may_v be_v say_v that_o both_o vomitives_n and_o purgative_n take_v some_o time_n before_o they_o operate_v unless_o a_o nausea_n upon_o aversion_n cause_v they_o to_o work_v soon_o for_o thing_n must_v have_v time_n to_o insinuate_v themselves_o or_o soak_v through_o the_o crusta_fw-la carnosa_fw-la of_o the_o stomach_n and_o afterward_o to_o affect_v its_o sensile_a coat_n which_o argue_v that_o wine_n and_o cordial_n which_o operate_v immediate_o do_v not_o operate_v that_o way_n but_o by_o fume_n or_o effuvium_n pass_v into_o the_o brain_n or_o blood_n answ._n i_o doubt_v indeed_o that_o this_o difference_n may_v be_v a_o occasion_n of_o refer_v the_o effect_n of_o cordial_n and_o those_o of_o emittick_n and_o cathartic_o to_o different_a cause_n but_o it_o be_v very_o strange_a that_o they_o shall_v go_v so_o far_o as_o the_o blood_n or_o brain_n to_o seek_v for_o the_o cause_n of_o the_o operation_n of_o cordial_n which_o operate_v in_o a_o moment_n and_o go_v no_o far_o than_o the_o stomach_n for_o the_o cause_n of_o the_o operation_n of_o vomatives_n and_o purgative_n which_o take_v more_o time_n to_o operate_v especial_o see_v the_o blood_n and_o brain_n have_v no_o sensation_n and_o that_o all_o sensitive_a comfort_n happen_v by_o that_o mean_n i_o think_v it_o be_v much_o more_o proper_a first_o to_o consider_v the_o immediate_a part_n upon_o which_o they_o insist_v when_o at_o stomach_n especial_o see_v it_o be_v so_o very_o sensible_a before_o we_o run_v rove_a i_o know_v not_o whither_o to_o seek_v for_o the_o cause_n of_o a_o thing_n that_o work_v please_v and_o comfort_v the_o stomach_n as_o soon_o as_o it_o be_v down_o i_o take_v myself_o run_v off_o the_o proper_a subject_a matter_n of_o this_o chapter_n and_o anticipate_v that_o of_o another_o therefore_o i_o will_v be_v short_a and_o deliver_v my_o opinion_n in_o this_o case_n by_o way_n of_o position_n with_o a_o familiar_a instance_n to_o illustrate_v it_o which_o may_v in_o some_o measure_n prepare_v you_o for_o the_o proof_n
of_o it_o and_o what_o be_v to_o be_v say_v thereof_o more_o at_o large_a hereafter_o i_o say_v then_o that_o hot_a spirituous_a cordial_n for_o such_o indeed_o all_o proper_a cordial_n be_v as_o brandy_n dr._n stephens_n water_n and_o suchlike_a have_v sulphureous_a particle_n so_o prepare_v and_o dispose_v towards_o heat_n or_o fire_n that_o they_o be_v as_o it_o be_v in_o potentia_fw-la proxima_fw-la or_o next_o disposition_n thereto_o be_v mighty_a apt_a to_o contract_v a_o heat_n as_o you_o find_v by_o spirit_n of_o wine_n or_o brandy_n keep_v the_o least_o time_n in_o a_o warm_a place_n or_o to_o come_v close_o to_o the_o matter_n in_o your_o mouth_n wherein_o be_v actuate_v by_o its_o heat_n they_o will_v as_o in_o a_o instant_n grow_v so_o hot_a and_o active_a that_o you_o can_v hardly_o bear_v they_o because_o particle_n of_o heat_n which_o penetrate_v any_o metal_n glass_n etc._n etc._n immediate_o as_o soon_o as_o apply_v thereto_o will_v much_o more_o easy_o and_o soon_o penetrate_v our_o soft_a part_n at_o mouth_n or_o the_o crusta_fw-la carnosa_fw-la at_o stomach_n and_o so_o reach_v the_o most_o sensile_a coat_n thereof_o please_v comfort_a and_o exciting_a the_o spiritus_fw-la insitos_fw-la as_o in_o a_o moment_n by_o their_o spirituous_a heat_n which_o we_o actual_o feel_v and_o sensible_o find_v to_o please_v and_o comfort_v the_o stomach_n but_o if_o some_o purge_v tincture_n have_v be_v put_v into_o the_o cordial_n or_o brandy_n this_o will_v not_o have_v soak_v through_o the_o crusta_fw-la carnosa_fw-la under_o some_o time_n and_o consequent_o not_o operate_v till_o it_o have_v this_o may_v be_v most_o manifest_o illustrate_v by_o some_o hot_a brandy_n or_o indeed_o any_o hot_a liquid_a put_v into_o a_o porous_a dish_n set_v upon_o one_o hand_n which_o present_o warm_v it_o but_o if_o the_o liquid_a be_v tinge_v with_o any_o thing_n that_o tincture_n will_v not_o reach_v the_o hand_n till_o the_o liquor_n which_o be_v its_o vehicle_n soak_v through_o which_o may_v be_v in_o a_o hour_n more_o or_o less_o according_a to_o the_o porosity_n of_o the_o wood_n which_o tincture_n be_v to_o be_v compare_v to_o the_o purgative_n at_o stomach_n hence_o it_o follow_v that_o all_o cordial_n shall_v be_v a_o spirituous_a liquid_a if_o intend_v for_o sudden_a refreshment_n which_o experience_n have_v teach_v and_o be_v give_v actual_o warm_v if_o a_o very_a nimble_a comfort_n be_v require_v though_o the_o great_a heat_n of_o the_o stomach_n above_o that_o of_o the_o mouth_n will_v general_o be_v sufficient_a thus_o may_v the_o stomach_n be_v please_v and_o comfort_v grieve_v and_o purge_v with_o the_o same_o draught_n but_o gracious_a providence_n have_v give_v the_o start_n to_o the_o cordial_n which_o immediate_o comfort_v we_o as_o a_o heater_n 30._o if_o opium_n operate_v by_o such_o fume_n it_o will_v at_o least_o in_o a_o liquid_a form_n begin_v its_o operation_n as_o soon_o as_o it_o be_v at_o stomach_n for_o it_o will_v begin_v to_o send_v up_o fume_n as_o soon_o as_o it_o begin_v to_o be_v warm_a which_o be_v present_o and_o be_v at_o a_o very_a considerable_a height_n of_o fume_v and_o consequent_o of_o operation_n in_o one_o minute_n which_o be_v about_o the_o space_n of_o seventy_o ordinary_a pulse_n but_o we_o do_v not_o find_v it_o begin_v to_o operate_v in_o that_o form_n under_o twenty_o thirty_o or_o forty_o minute_n which_o be_v much_o about_o the_o time_n that_o a_o more_o agreeable_a and_o not_o nauseated_a vomitive_a or_o purger_n begin_v to_o affect_v the_o sensile_a coat_n of_o the_o stomach_n and_o give_v intimation_n of_o their_o so_o do_v all_o which_o and_o the_o sense_n of_o pleasure_n that_o we_o actual_o then_o seel_v at_o stomach_n make_v it_o probable_a that_o it_o operate_v by_o affect_v the_o stomach_n pleasant_o and_o comfortable_o after_o the_o manner_n of_o generous_a wine_n as_o purger_n and_o vomatives_n do_v by_o affect_v it_o grievous_o all_o of_o they_o except_o the_o wine_n that_o please_v and_o comfort_v soon_o because_o of_o its_o particle_n of_o heat_n gain_v by_o fermentation_n operate_a much_o in_o the_o same_o time_n because_o they_o take_v like_o leisure_n to_o soak_v through_o the_o crusta_fw-la carnosa_fw-la to_o the_o sensile_a coat_n of_o the_o stomach_n 31._o all_o sensitive_a pleasure_n comfort_n etc._n etc._n be_v receive_v by_o the_o sense_n and_o though_o any_o part_n be_v some_o way_n benefit_v that_o have_v no_o sense_n no_o comfort_n will_v be_v perceive_v without_o perception_n none_o can_v say_v that_o he_o be_v comfort_v what_o fit_a part_n be_v there_o to_o be_v please_v and_o comfort_v by_o sensation_n than_o the_o stomach_n which_o have_v such_o exquisite_a sense_n that_o it_o can_v discern_v the_o vomitory_n particle_n in_o infusion_n of_o the_o grocus_n or_o regulus_n of_o antimony_n which_o no_o sensation_n but_o that_o at_o stomach_n can_v discern_v and_o so_o small_a that_o a_o thousand_o vomitory_n make_v thereof_o by_o infusion_n do_v not_o sensible_o diminish_v the_o grocus_n or_o regulus_n as_o to_o weight_n or_o bulk_n nor_o can_v i_o conceive_v where_o any_o sensible_a comfort_n can_v be_v perceive_v by_o a_o spoonful_n of_o cordial_n but_o at_o stomach_n where_o it_o actual_o be_v and_o upon_o who_o coat_n it_o immediate_o insist_o be_v it_o not_o there_o that_o we_o feel_v the_o comfort_n and_o where_o shall_v we_o find_v it_o but_o there_o what_o will_v the_o effluvium_n of_o a_o spoonful_n signify_v if_o mix_v with_o 100000_o time_n as_o much_o insensile_a blood_n and_o what_o part_n beside_o the_o stomach_n that_o the_o blood_n touch_v can_v be_v sensible_a of_o it_o so_o that_o if_o effluvium_n be_v grant_v it_o be_v thither_o they_o must_v return_v to_o cause_v any_o considerable_a pleasure_n or_o comfort_n but_o what_o need_v any_o reâ—urn_n of_o the_o inconsiderable_a effluvia_fw-la when_o the_o main_a body_n of_o the_o cordial_n yea_o all_z lie_v upon_o the_o stomach_n already_o i_o must_v forbear_v run_v into_o the_o business_n of_o other_o chapter_n have_v be_v tedious_a enough_o upon_o the_o subject_a of_o this_o and_o the_o rather_o because_o it_o be_v so_o general_a and_o so_o root_v a_o opinion_n in_o the_o mind_n of_o man_n in_o all_o age_n and_o in_o all_o sect_n of_o physician_n and_o natural_a philosopher_n that_o i_o can_v not_o say_v too_o much_o to_o endeavour_v to_o free_v the_o world_n from_o the_o slavery_n of_o such_o a_o imposition_n and_o the_o innumerable_a ill_a consequence_n of_o such_o a_o fundamental_a and_o overgrow_a error_n which_o certain_o must_v have_v be_v long_o since_o explode_v if_o ingenious_a man_n have_v first_o think_v and_o then_o speak_v free_o but_o the_o truth_n be_v there_o be_v many_o and_o great_a cause_n to_o the_o contrary_a as_o those_o intimate_v in_o the_o last_o paragraph_n and_o the_o mighty_a usefulness_n and_o ready_a officiousness_n of_o that_o opinion_n of_o fume_n to_o answer_v for_o all_o the_o more_o obscure_a and_o latent_fw-la cause_n of_o the_o malady_n and_o disaster_n of_o the_o brain_n and_o genus_fw-la nervosum_fw-la if_o any_o inquire_v or_o call_v for_o the_o cause_n of_o a_o vertigo_n the_o physician_n answer_v fume_n of_o epilepsy_n it_o be_v answer_v fume_n of_o scotomy_n it_o be_v fume_n of_o headache_n migraine_n coma_n caros_n lethargy_n etc._n etc._n it_o be_v fume_n of_o hysterick_n fit_n convulsion_n spasm_n cramp_n etc._n etc._n it_o be_v fume_n nay_o they_o answer_v as_o cause_n to_o all_o distillation_n catarrh_n epiphora_n or_o weep_v eye_n and_o all_o even_o ordinary_a tear_n all_o which_o they_o say_v be_v only_o these_o fume_n turn_v into_o water_n by_o the_o coldness_n of_o the_o brain_n as_o they_o be_v in_o a_o still_o or_o alembick_a so_o hot_a fume_n account_v for_o frenzy_n delirium_n rave_n etc._n etc._n so_o that_o however_o other_o head_n be_v the_o physician_n be_v be_v stuff_v therewith_o and_o all_o meteor_n of_o the_o microcosm_n upper_a region_n whether_o hot_a or_o cold_a be_v as_o those_o in_o the_o macrocosm_n form_v out_o of_o fume_n as_o he_o imagine_v thus_o you_o see_v all_o the_o opinion_n and_o hypothesise_n that_o have_v be_v concern_v the_o operation_n of_o opium_n to_o be_v most_o absurd_a and_o direct_o contrary_a to_o all_o sense_n reason_n and_o experience_n chap._n xi_o opium_n do_v not_o diminish_v or_o disable_v the_o spirit_n by_o any_o mean_n whatsoever_o have_v sufficient_o demonstrate_v that_o opium_n can_v diminish_v or_o disable_v the_o spirit_n by_o the_o cold_a quality_n of_o the_o ancient_n or_o fume_n of_o the_o modern_n and_o that_o neither_o of_o they_o have_v as_o much_o as_o any_o be_v i_o shall_v now_o add_v that_o opium_n do_v not_o diminish_v or_o disable_v the_o spirit_n by_o any_o other_o mean_n whatsoever_o i_o will_v not_o be_v mistake_v when_o i_o say_v that_o opium_n do_v not_o diminish_v or_o disable_v
the_o spirit_n by_o any_o mean_n for_o there_o be_v nothing_o so_o good_a in_o nature_n but_o will_v do_v it_o if_o use_v undue_o or_o immoderate_o as_o wine_n bread_n milk_n honey_n sugar_n beer_n etc._n etc._n in_o excess_n for_o i_o intend_v that_o it_o do_v not_o do_v it_o when_o due_o and_o moderate_o use_v 1._o that_o which_o refresh_v the_o weary_a and_o high_o prevent_v weariness_n must_v add_v to_o or_o excite_v the_o spirit_n which_o be_v direct_o contrary_a to_o diminish_v or_o disable_n they_o but_o opium_n do_v in_o a_o most_o eminent_a manner_n refresh_v the_o weary_v and_o prevent_v weariness_n therefore_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n some_o have_v be_v so_o silly_a and_o inadvertent_n as_o to_o object_n that_o it_o refresh_v the_o weary_a only_o by_o sleep_n it_o be_v matter_n of_o fact_n that_o it_o refresh_v they_o whether_o they_o sleep_v or_o no_o and_o that_o without_o fail_v as_o often_o as_o it_o be_v use_v in_o that_o case_n other_o that_o be_v no_o wise_a have_v say_v that_o it_o only_o take_v off_o the_o sense_n of_o weariness_n by_o stupify_a which_o happen_v by_o the_o diminish_n or_o disable_n of_o the_o animal_n spirit_n bare_a insensibleness_n can_v enable_v the_o spirit_n to_o labour_n with_o eminent_a briskness_n and_o alacrity_n as_o man_n most_o certain_o do_v after_o opium_n be_v take_v be_v fine_o enliven_v and_o invigorate_v as_o with_o generous_a wine_n if_o they_o do_v not_o know_v this_o to_o be_v true_a let_v they_o for_o shame_n hold_v their_o tongue_n till_o they_o know_v matter_n of_o fact_n which_o if_o they_o will_v not_o they_o proclaim_v themselves_o to_o be_v idle_a and_o impertinent_a babbler_n but_o if_o they_o will_v patient_o and_o wise_o abstain_v argue_v till_o they_o be_v satisfy_v as_o to_o matter_n of_o fact_n then_o will_v they_o be_v past_a opinion_n and_o hypothesis_n in_o that_o case_n for_o they_o will_v have_v sensible_a and_o certain_a knowledge_n of_o the_o contrary_a and_o the_o truth_n of_o what_o i_o say_v which_o will_v end_v all_o controversy_n and_o precarious_a squabble_n upon_o false_a supposition_n as_o the_o manner_n be_v that_o can_v lead_v they_o to_o what_o be_v right_o but_o by_o mere_a chance_n and_o never_o to_o a_o true_a knowledge_n that_o they_o be_v in_o the_o right_n which_o make_v it_o none_o in_o effect_n for_o they_o can_v do_v nothing_o with_o assurance_n but_o only_o suppose_v and_o hope_v they_o be_v in_o the_o right_n when_o they_o be_v as_o much_o out_o to_o their_o patient_n sorrow_n as_o physician_n have_v be_v in_o the_o cold_a quality_n and_o fume_n of_o opium_n it_o be_v true_a that_o a_o grain_n or_o two_o of_o opium_n will_n if_o a_o man_n compose_v himself_o sit_v or_o lie_v still_o cause_n a_o sleepiness_n equal_a to_o that_o cause_v by_o spend_v the_o spirit_n by_o a_o day_n be_v labour_n but_o spend_v of_o the_o spirit_n be_v not_o the_o only_a no_o nor_o best_a proportion_v or_o more_o adequate_a cause_n thereof_o as_o i_o have_v show_v if_o loss_n of_o spirit_n be_v the_o adequate_a cause_n of_o sleep_n how_o shall_v good_a and_o generous_a wine_n cause_n sleepiness_n after_o that_o eminent_a rate_n as_o it_o do_v in_o most_o people_n how_o shall_v the_o most_o please_a music_n incline_v such_o as_o lie_v or_o sit_v still_o to_o sleep_v but_o if_o one_o dance_n thereto_o it_o make_v he_o more_o lively_a and_o brisk_a than_o ordinary_a the_o like_a exact_o do_v wine_n and_o opium_n if_o man_n lie_v or_o sit_v still_o but_o otherwise_o they_o make_v they_o much_o more_o brisk_a and_o lively_a and_o able_a to_o undergo_v labour_n action_n etc._n etc._n which_o note_n that_o you_o may_v not_o any_o more_o wonder_n that_o enlivener_n and_o exciter_n of_o the_o spirit_n do_v cause_n sleep_v as_o well_o as_o diminisher_n thereof_o and_o observe_v that_o they_o be_v all_o please_a thing_n as_o music_n wine_n and_o opium_n which_o cause_n pleasant_a dream_n pleasant_a watch_n pleasant_a humour_n etc._n etc._n expect_v more_o of_o this_o matter_n in_o the_o follow_a chapter_n and_o all_o by_o degree_n according_a as_o i_o judge_v the_o prejudice_v world_n will_v bear_v thing_n for_o a_o great_a paradox_n how_o true_a soever_o must_v not_o be_v abrupt_o obtrude_v but_o gentle_o and_o gradual_o usher_v in_o by_o insinuate_v reason_v otherwise_o it_o will_v be_v entertain_v like_o a_o rude_a stranger_n that_o contradict_v a_o multitude_n in_o fashion_n and_o custom_n that_o they_o have_v always_o use_v and_o judge_v to_o be_v the_o very_o best_o however_o unblamable_a consider_v that_o if_o opium_n diminish_v or_o disable_v the_o spirit_n proportionable_a to_o the_o sleepiness_n that_o it_o cause_n as_o a_o hard_a day_n be_v labour_n do_v then_o if_o opium_n be_v give_v a_o man_n after_o a_o hard_a day_n be_v labour_n it_o will_v be_v as_o it_o be_v add_v another_o hard_a day_n be_v labour_v to_o cure_v it_o the_o day_n be_v labour_n and_o opium_n impair_n the_o spirit_n alike_o think_v what_o a_o miserable_a condition_n the_o poor_a man_n will_v be_v in_o especial_o if_o sleep_n do_v not_o make_v he_o some_o amends_o it_o will_v be_v such_o as_o be_v utter_o intolerable_a but_o so_o far_o be_v opium_n from_o any_o such_o effect_n that_o it_o refresh_v he_o though_o he_o sleep_v not_o at_o all_o after_o the_o hard_a day_n be_v labour_n and_o not_o only_o so_o but_o will_v enable_v he_o to_o work_v all_o the_o follow_a night_n with_o great_a alacrity_n if_o need_n require_v it_o what_o a_o condition_n will_v those_o be_v in_o who_o take_v a_o drachm_n of_o it_o twice_o a_o day_n for_o 10_o 20_o or_o 30_o year_n nay_o how_o can_v any_o possible_o do_v it_o for_o half_a 10_o day_n if_o a_o grain_n or_o two_o destroy_v the_o spirit_n so_o much_o as_o to_o cause_v sleepiness_n thereby_o as_o hard_a labour_n do_v which_o they_o must_v allow_v that_o assert_v it_o cause_n sleep_v by_o diminish_v or_o disable_n the_o spirit_n but_o some_o may_v say_v though_o very_o inconsiderate_o that_o it_o only_o disable_v they_o for_o the_o time_n of_o its_o operation_n that_o be_v strange_a indeed_o consider_v that_o even_o during_o that_o time_n they_o be_v most_o enable_v to_o work_n or_o labour_n though_o tire_v before_o and_o that_o it_o 2._o cause_n comfort_n refreshment_n ovation_n of_o the_o spirit_n all_o the_o time_n of_o its_o operation_n as_o wine_n moderate_o take_v do_v especial_o if_o people_n keep_v themselves_o in_o action_n labour_n etc._n etc._n otherwise_o indeed_o they_o may_v fall_v asleep_a upon_o the_o comfortable_a satisfaction_n contentation_n of_o mind_n and_o acquiescence_n of_o spirit_n that_o it_o occasion_n as_o wine_n do_v 3._o the_o first_o effect_n that_o we_o find_v of_o opium_n which_o may_v therefore_o probable_o be_v a_o very_a lead_n fundamental_a and_o significant_a effect_n be_v that_o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o incline_v he_o to_o sleep_n if_o not_o it_o make_v he_o gay_a good_a humour_a brave_a etc._n etc._n it_o be_v a_o pleasure_n so_o sweet_a and_o delicious_a that_o though_o i_o endeavour_v to_o express_v it_o by_o the_o ovation_n of_o the_o spirit_n upon_o joy_n a_o good_a genius_n inform_v a_o man_n or_o the_o helmâ—sians_n archaeus_n in_o his_o best_a humour_n or_o a_o continual_a vâ—real_a pleasure_n wine_n drink_v ad_fw-la hilaritatem_fw-la etc._n etc._n yet_o i_o doubt_v all_o my_o way_n of_o express_v it_o do_v come_v short_a of_o the_o charm_a complacency_n that_o it_o cause_n therefore_o if_o wine_n music_n a_o good_a meal_n agreeable_a frication_n of_o the_o head_n or_o back_o the_o sound_n of_o water_n etc._n etc._n do_v incline_v we_o to_o sleep_v by_o the_o pleasure_n thereof_o which_o lull_v and_o soothe_v we_o to_o it_o as_o be_v most_o certain_a if_o we_o sit_v or_o lie_v still_o much_o more_o must_v the_o high_a charm_n of_o opium_n cause_n it_o that_o it_o be_v a_o pleasure_n that_o affect_v by_o one_o of_o our_o sense_n namely_o by_o feel_v be_v indisputable_a for_o it_o be_v not_o a_o pleasure_n of_o the_o eye_n nose_n tongue_n or_o ear_n and_o it_o must_v be_v sensitive_a because_o cause_v by_o matter_n and_o that_o opium_n have_v doubtless_o the_o like_a effect_n upon_o brute_n who_o have_v no_o other_o pleasure_n but_o what_o be_v sensitive_a that_o it_o be_v at_o stomach_n be_v also_o evident_a where_o we_o can_v be_v please_v only_o by_o the_o sense_n of_o feel_v that_o it_o be_v involuntary_a and_o please_v we_o whether_o we_o will_v or_o no_o and_o that_o the_o same_o particle_n excite_v venery_n itch_a etc._n etc._n now_o all_o the_o sense_n especial_o feel_v and_o particular_o that_o at_o stomach_n be_v give_v we_o for_o
of_o man_n because_o of_o its_o ill_a effect_n lavish_o use_v therefore_o none_o can_v argue_v from_o that_o that_o opium_n diminish_v or_o disable_v the_o spirit_n any_o more_o than_o wine_n or_o bread_n do_v a_o surfeit_n of_o which_o be_v most_o dangerous_a omnis_fw-la repletio_fw-la mala_fw-la panis_n vero_fw-la pessima_fw-la &_o corruptio_fw-la optimi_fw-la est_fw-la pessima_fw-la that_o be_v all_o repletion_n be_v bad_a but_o that_o of_o bread_n be_v the_o worst_a and_o the_o corruption_n of_o the_o best_a be_v the_o worst_a the_o short_a be_v this_o wine_n and_o opium_n agree_v in_o all_o their_o effect_n save_v such_o as_o be_v consequence_n of_o their_o different_a accident_n as_o the_o quantity_n of_o wine_n that_o must_v be_v use_v to_o cause_v the_o same_o effect_n with_o a_o little_a opium_n and_o wine_n have_v be_v ferment_v and_o opium_n as_o may_v be_v show_v have_v some_o crude_a and_o viscid_a rosin_n in_o it_o which_o sometime_o stick_v to_o the_o crusta_fw-la carnosa_fw-la etc._n etc._n of_o the_o stomach_n whence_o it_o happen_v that_o wine_n load_v one_o more_o heat_v more_o and_o be_v more_o troublesome_a upon_o those_o account_n and_o that_o opium_n offend_v the_o stomach_n often_o even_o in_o a_o moderate_a do_v cause_v vomit_n hiccough_n anxiety_n distress_n at_o stomach_n deliquium_n etc._n etc._n because_o of_o the_o indigestible_a rosin_n stick_v to_o the_o side_n of_o the_o most_o sensile_a stomach_n as_o i_o shall_v far_o prove_v hereafter_o by_o god_n help_n show_v very_o easy_a way_n and_o mean_n to_o separate_v that_o rosin_n and_o so_o make_v it_o as_o safe_a and_o less_o troublesome_a as_o it_o be_v more_o effectual_a than_o wine_n opium_n can_v diminish_v or_o disable_v the_o spirit_n because_o as_o have_v be_v prove_v it_o send_v no_o part_n fume_v or_o effluvium_fw-la to_o the_o brain_n or_o animal_n spirit_n to_o cause_v such_o bad_a effect_n while_o it_o be_v at_o stomach_n yet_o do_v it_o produce_v they_o while_o it_o be_v there_o for_o as_o the_o vaporarians_n themselves_o and_o indeed_o all_o man_n allow_v there_o can_v be_v no_o destruction_n without_o contact_n sanctorius_n do_v well_o and_o true_o observe_v by_o the_o help_n of_o his_o static_o that_o nothing_o cause_v liberal_a perspiration_n but_o it_o raise_v the_o spirit_n it_o be_v most_o certain_a that_o nothing_o in_o nature_n open_v the_o pore_n and_o cause_n perspiration_n more_o than_o opium_n therefore_o nothing_o shall_v according_a to_o his_o observation_n elevate_v the_o spirit_n more_o and_z indeed_o nothing_o do_v as_o appear_v by_o all_o that_o have_v be_v say_v and_o will_v yet_o more_o plain_o appear_v loss_n of_o memory_n by_o opium_n as_o some_o argue_v be_v not_o so_o much_o a_o loss_n of_o spirit_n as_o lanity_n of_o the_o brain_n for_o people_n in_o drink_n do_v not_o want_v spirit_n but_o there_o be_v a_o great_a relaxation_n of_o the_o brain_n and_o its_o membrane_n and_o of_o the_o whole_a jenus_fw-la 〈◊〉_d which_o relaxation_n cause_v a_o soft_a loose_a and_o labile_fw-la brain_n that_o like_o liquid_a thing_n retain_v no_o impression_n beside_o that_o i_o shall_v god_n will_v show_v you_o hereafter_o that_o impression_n can_v be_v so_o well_o make_v upon_o the_o sensitive_a soul_n by_o the_o animal_n spirit_n upon_o relaxation_n of_o the_o sensible_a part_n as_o in_o sleep_n etc._n etc._n for_o a_o very_a plain_a mechanical_a reason_n to_o be_v show_v in_o due_a time_n thus_o have_v i_o by_o the_o assistance_n of_o its_o maker_n who_o best_o know_v it_o clear_v opium_n from_o the_o false_a aspersion_n of_o a_o extreme_a cold_a quality_n and_o parcotick_a fume_n both_o which_o be_v common_o call_v venomous_a fatal_a and_o by_o all_o the_o ill_a name_n imaginable_a but_o as_o good_a luck_n be_v they_o abuse_v nothing_o because_o it_o be_v manifest_a that_o there_o be_v no_o such_o thing_n nor_o have_v it_o any_o quality_n by_o which_o it_o diminish_v or_o disable_v the_o spirit_n as_o be_v most_o evident_a from_o the_o premise_n so_o that_o all_o that_o have_v be_v say_v of_o opium_n by_o way_n of_o hypothesis_n to_o explain_v its_o effect_n depend_v upon_o its_o diminish_n or_o disable_n the_o spirit_n by_o a_o cold_a quality_n or_o fume_n be_v come_v to_o nothing_o i_o wish_v it_o have_v be_v as_o innocent_a chap._n xii_o show_v what_o must_v be_v the_o true_a cause_n of_o the_o operation_n of_o opium_n all_o the_o general_a foundation_n upon_o which_o author_n either_o ancient_a or_o modern_a erect_v their_o several_a hypothesise_n concern_v the_o operation_n of_o opium_n have_v as_o manifest_o appear_v no_o real_a existence_n what_o enchant_a castle_n in_o the_o air_n or_o vain_a phantasm_n must_v their_o structure_n be_v and_o how_o like_a delude_a wizzard_n must_v they_o appear_v while_o they_o seem_v to_o take_v high_a flight_n and_o glorious_a prospect_n of_o cause_n that_o have_v no_o reality_n thus_o be_o i_o leave_v utter_o destitute_a of_o either_o foundation_n or_o model_n unless_o i_o find_v out_o that_o and_o frame_v this_o which_o i_o hope_v may_v be_v easy_o do_v because_o the_o cloudy_a supposition_n of_o vapour_n have_v vanish_v away_o there_o now_o remain_v but_o two_o way_n by_o which_o a_o internal_a medicament_n can_v operate_v viz._n 1._o as_o a_o alterative_a of_o the_o blood_n etc._n etc._n or_o 2._o as_o affect_v the_o sense_n of_o feel_v either_o grievous_o as_o vomit_n purger_n etc._n etc._n or_o pleas_o as_o cordial_n generous_a wine_n titillate_v amphrodisiack_n comfortable_a warmth_n anodynes_n and_o such_o like_a that_o please_v the_o nerve_n and_o membrane_n which_o way_n of_o operate_n be_v too_o little_o observe_v by_o physician_n though_o they_o take_v great_a notice_n of_o the_o operation_n of_o thing_n by_o grievous_a sensation_n as_o irritative_n to_o vomit_n purge_v salivate_a etc._n etc._n by_o their_o acrimony_n whereas_o the_o pleaser_n of_o sensation_n which_o must_v as_o contrary_n have_v contrary_a operation_n be_v little_o regard_v or_o think_v of_o 1._o opium_n do_v not_o operate_v as_o a_o alterative_a of_o the_o blood_n etc._n etc._n first_o because_o it_o operate_v while_o it_o be_v at_o stomach_n or_o at_o least_o before_o it_o arrive_v at_o the_o blood_n which_o manifest_o appear_v several_a way_n as_o 1._o because_o it_o often_o operate_v in_o a_o liquid_a form_n in_o few_o minute_n and_o very_o common_o in_o a_o quarter_n of_o a_o hour_n in_o which_o time_n it_o must_v be_v at_o stomach_n or_o at_o least_o far_o from_o arrive_v at_o the_o blood_n 2._o because_o it_o have_v be_v very_o often_o vomit_v up_o after_o it_o have_v operate_v and_o produce_v its_o usual_a effect_n for_o 1_o 2_o 3_o 4_o 5_o 6_o 8_o 10_o and_o sometime_o more_o hour_n as_o evident_o appear_v by_o the_o smell_n colour_n taste_v etc._n etc._n of_o what_o be_v vomit_v and_o by_o its_o operation_n cease_v after_o such_o vomit_v of_o which_o common_a experience_n and_o author_n do_v inform_v we_o see_v helmont_n ius_n duumvir_fw-la 62._o where_o he_o tell_v of_o opium_n operate_a at_o night_n and_o vomit_v up_o next_o morning_n 3._o it_o be_v bare_a cause_v vomit_v after_o it_o have_v operate_v for_o a_o good_a while_n be_v of_o itself_o though_o its_o taste_n smell_v etc._n etc._n do_v not_o discover_v it_o a_o infallible_a argument_n of_o its_o operate_n while_o it_o be_v at_o stomach_n for_o it_o be_v against_o all_o reason_n to_o imagine_v that_o thing_n shall_v irritate_fw-la it_o to_o vomit_n after_o they_o be_v go_v into_o the_o blood_n and_o not_o do_v it_o while_o they_o be_v in_o the_o stomach_n itself_o as_o all_o vomitory_n do_v the_o reason_n why_o it_o stay_v so_o long_o at_o stomach_n be_v 1._o it_o be_v indigestibleness_n which_o plain_o appear_v by_o stool_n urine_n and_o sweat_v smell_v of_o it_o when_o take_v in_o any_o considerable_a quantity_n all_o the_o coction_n digestion_n circulation_n etc._n etc._n that_o it_o pass_v in_o the_o body_n signify_v very_o little_a to_o it_o which_o its_o cause_v itch_n in_o the_o skin_n and_o affect_v the_o venereal_a membrane_n after_o its_o pass_v the_o blood_n do_v also_o argue_v 2._o the_o clamminess_n of_o its_o resinous_a part_n stick_v to_o the_o stomach_n cause_n as_o i_o shall_v plain_o prove_v hereafter_o its_o long_a stay_n in_o it_o for_o if_o the_o rosin_n be_v separate_v from_o it_o it_o will_v not_o then_o make_v such_o a_o long_a stay_n at_o stomach_n as_o i_o have_v often_o experience_v 4._o we_o actual_o feel_v it_o cause_v a_o sense_n of_o pleasure_n at_o stomach_n during_o its_o operation_n therefore_o it_o be_v then_o in_o it_o 5._o it_o have_v be_v carry_v off_o by_o stool_n after_o it_o have_v produce_v its_o usual_a effect_n therefore_o it_o operate_v before_o it_o arrive_v at_o the_o blood_n 6._o all_o observer_n do_v allow_v that_o opium_n operate_v while_o it_o be_v at_o stomach_n
sleep_v be_v the_o sound_a and_o that_o sleep_v gradual_o decline_v in_o degree_n as_o we_o be_v recruit_v till_o we_o awake_v the_o near_a which_o we_o be_v the_o more_o we_o dream_v the_o state_n of_o dream_v be_v a_o kind_n of_o twilight_n between_o sound_a sleep_n and_o awake_v or_o between_o a_o full_a somniferous_a relaxation_n and_o vigilative_a contraction_n and_o as_o the_o sensitive_a soul_n use_v all_o degree_n of_o contraction_n below_o that_o of_o the_o vigilative_a till_o it_o come_v to_o bare_a compression_n of_o the_o air_n so_o it_o can_v exercise_v super-vigilative_a contraction_n if_o i_o may_v so_o call_v it_o that_o be_v much_o high_a degree_n thereof_o than_o what_o be_v requisite_a ordinary_o for_o a_o state_n of_o vigilancy_n as_o in_o case_n of_o danger_n to_o the_o animal_n fright_v terror_n grievous_a passion_n and_o sensation_n by_o which_o mean_v the_o animal_n spirit_n be_v more_o compress_v than_o under_o the_o ordinary_a vigilative_a contraction_n sensation_n grow_v more_o nice_a and_o smart_a and_o motion_n more_o prompt_a and_o vigorous_a they_o always_o go_v together_o for_o the_o defence_n of_o the_o animal_n by_o extraordinary_a flight_n repulsion_n or_o otherwise_o hence_o it_o be_v upon_o fear_n terror_n grievous_a passion_n or_o sensation_n which_o manifest_o prove_v the_o be_v of_o such_o a_o extraordinary_a contraction_n upon_o such_o occasion_n that_o 1._o perspiration_n sail_v in_o a_o yet_o high_o degree_n than_o under_o bare_a or_o ordinary_a vigilative_a contraction_n as_o appear_v by_o infallible_a statick_a experiment_n and_o demonstration_n 2._o it_o be_v by_o reason_n of_o the_o say_v defensive_a contraction_n for_o so_o i_o call_v it_o because_o it_o be_v excite_v in_o a_o extraordinary_a manner_n for_o the_o defence_n of_o the_o animal_n in_o time_n of_o need_n or_o great_a exigence_n that_o in_o fright_v terror_n etc._n etc._n our_o hair_n dog_n etc._n etc._n do_v stand_v on_o end_n or_o more_o upright_o 1._o because_o the_o pore_n do_v by_o that_o violent_a contraction_n strict_o close_a about_o the_o root_n of_o the_o hair_n that_o it_o can_v swag_v incline_v or_o yield_v any_o way_n by_o reason_n of_o its_o weight_n etc._n etc._n as_o when_o the_o skin_n be_v more_o lax_n and_o soft_a and_o the_o pore_n wherein_o the_o hair_n be_v fix_v more_o open_a 2._o because_o which_o be_v the_o main_a reason_n the_o say_a contraction_n render_v the_o oblique_a pore_n more_o upright_o as_o suppose_v the_o pore_n and_o hair_n do_v natural_o stand_v oblique_o as_o they_o do_v to_o carry_v off_o wet_a etc._n etc._n as_o in_o fig._n 1._o fig_n i_o fig_n two_o and_o that_o a_o in_o fig._n 1._o be_v by_o the_o say_a contraction_n bring_v near_a to_o ay_o as_o much_o as_o be_v from_o a_o to_o o_o then_o will_v the_o pore_n and_o hair_n stand_v upright_o as_o in_o fig._n 2._o and_o the_o skin_n a_o o_o e_o i_o s_o contract_v and_o bring_v within_o the_o prick_v perpendicular_o whereas_o in_o fig._n 1._o it_o excure_v beyond_o the_o perpendicular_a n_z m_z as_o much_o as_o be_v from_o a_o to_o o._n 3._o for_o the_o same_o reason_n it_o be_v that_o the_o face_n in_o grievous_a passion_n and_o sensation_n as_o acute_a pain_n etc._n etc._n be_v contort_a and_o wring_v awry_o as_o you_o see_v in_o person_n that_o cry_v because_o of_o grievance_n after_o the_o same_o manner_n as_o when_o they_o strive_v to_o lift_v up_o a_o great_a weight_n and_o that_o at_o the_o same_o time_n tear_n and_o moisture_n at_o nose_n and_o mouth_n be_v squeeze_v out_o by_o the_o same_o contraction_n which_o make_v people_n use_v the_o say_v of_o casting_n snot_n about_o when_o man_n cry_v it_o be_v for_o the_o same_o reason_n that_o people_n mouth_n water_n extreme_o when_o they_o be_v trim_v with_o a_o bad_a razor_n that_o put_v they_o to_o pain_n which_o contract_v the_o part_n and_o squeeze_v out_o the_o spital_n 4._o the_o pulse_n grow_v sensible_o narrow_a and_o hard_a by_o the_o same_o contraction_n 5._o it_o be_v by_o the_o contraction_n upon_o grievous_a sensation_n that_o our_o mouth_n water_n very_o much_o upon_o a_o nausea_n at_o stomach_n because_o of_o the_o continuity_n of_o the_o membrane_n of_o the_o mouth_n and_o stomach_n 6._o the_o same_o contraction_n be_v the_o true_a reason_n why_o people_n upon_o hunger_n which_o be_v a_o grievous_a sensation_n at_o stomach_n have_v so_o much_o moisture_n or_o spital_n in_o their_o mouth_n and_o so_o much_o the_o more_o when_o they_o see_v good_a victual_n and_o can_v have_v it_o because_o the_o grievance_n which_o cause_v the_o contraction_n that_o squeeze_v it_o out_o be_v by_o so_o much_o the_o great_a this_o be_v the_o cause_n why_o the_o mouth_n water_n when_o hungry_a people_n see_v or_o smell_v good_a victual_n by_o the_o same_o contraction_n moisture_n be_v squeeze_v out_o into_o the_o oesophagus_n or_o gullet_n and_o the_o menstruum_fw-la into_o the_o stomach_n at_o the_o same_o time_n where_o observe_v god_n good_a and_o wise_a providence_n that_o hunger_n which_o call_v for_o meat_n at_o the_o same_o time_n provide_v spital_n to_o lubricate_v it_o for_o swollow_v and_o to_o help_v digestion_n render_v the_o gullet_n slippery_a and_o distensible_a and_o cause_v the_o menstruum_fw-la to_o flow_v more_o abundant_o into_o the_o stomach_n and_o all_o this_o when_o most_o need_v and_o that_o exact_o in_o proportion_n to_o the_o hunger_n or_o grievous_a sensation_n that_o cause_v the_o contraction_n it_o be_v well_o worth_a your_o nothing_o that_o god_n wisdom_n do_v always_o cause_v the_o want_n of_o what_o be_v necessary_a in_o sensile_a creature_n to_o be_v the_o solicit_v and_o urge_v cause_n for_o supply_v that_o a_o due_a proportion_n may_v be_v observe_v between_o the_o supply_n and_o the_o want_n which_o may_v upon_o the_o tell_n of_o it_o appear_v so_o plain_a a_o case_n that_o it_o be_v scarce_o worth_a the_o mention_v but_o believe_v i_o it_o be_v so_o little_o observe_v as_o plain_a as_o it_o may_v seem_v to_o be_v that_o people_n have_v and_o do_v err_v extravagant_o for_o want_n of_o note_v it_o which_o if_o they_o have_v note_v they_o can_v never_o have_v say_v that_o vapour_n or_o the_o retire_n of_o spirit_n into_o the_o brain_n etc._n etc._n be_v the_o cause_n or_o call_v of_o natural_a sleep_n nor_o feign_v menstruum_n to_o be_v the_o cause_n of_o hunger_n but_o will_v have_v due_o consider_v what_o be_v main_o supply_v by_o eat_v or_o recruit_v by_o sleep_v etc._n etc._n and_o then_o have_v nothing_o to_o do_v but_o to_o conclude_v the_o defect_n of_o that_o to_o have_v be_v the_o cause_n that_o solicit_v for_o the_o supply_n in_o proportion_n to_o the_o defect_n which_o if_o observe_v will_v most_o natural_o and_o easy_o lead_v you_o to_o the_o true_a knowledge_n of_o the_o cause_n of_o all_o appetite_n in_o a_o animal_n upon_o a_o few_o minute_n consideration_n for_o want_v of_o which_o most_o plain_a and_o one_o will_v think_v very_o obvious_a method_n the_o deviate_a world_n have_v sad_o puzzle_v itself_o about_o the_o cause_n of_o hunger_n thirst_v sleep_v and_o the_o like_a to_o this_o day_n and_o still_o be_v in_o dispute_n about_o they_o of_o which_o though_o my_o advertent_fw-la reader_n may_v well_o prevent_v i_o by_o use_v that_o natural_a method_n i_o shall_v god_n will_v give_v a_o account_n in_o my_o tract_n of_o animal_n mechanism_n only_a note_n here_o that_o i_o do_v not_o mean_v bare_a privative_a defect_n as_o such_o to_o be_v the_o positive_a cause_n but_o that_o the_o defect_n of_o what_o keep_v or_o guard_v the_o stomach_n etc._n etc._n from_o the_o grievance_n cause_v other_o matter_n to_o grieve_v it_o cause_n hunger_n etc._n etc._n without_o which_o mean_n no_o proportion_n can_v be_v observe_v between_o hunger_n and_o what_o take_v it_o away_o or_o our_o food_n 7._o the_o same_o defensive_a contraction_n do_v upon_o grievous_a sensation_n as_o pain_n cold_a terror_n etc._n etc._n cause_n a_o corrugation_n of_o the_o scrotum_fw-la contract_v the_o skin_n into_o little_a tubercle_n like_o that_o of_o a_o goose-skin_n etc._n etc._n 8._o by_o it_o upon_o grievous_a sensation_n as_o by_o squeeze_v the_o nose_n very_o hard_o pull_v the_o hair_n sand_n or_o any_o such_o thing_n in_o the_o eye_n or_o a_o grievance_n by_o the_o volatile_a particle_n of_o onion_n mustard_n horse-radish-root_n etc._n etc._n the_o part_n and_o membrane_n about_o the_o eye_n contract_v squeeze_v out_o tear_n that_o what_o grieve_v the_o eye_n may_v thereby_o be_v wash_v away_o or_o qualify_v as_o much_o as_o the_o tear_n can_v do_v it_o 9_o by_o this_o contraction_n repel_v the_o blood_n the_o skin_n grow_v pale_a by_o cold_a fear_v pain_n etc._n etc._n which_o also_o close_v the_o pore_n stop_v sweat_n as_o in_o a_o moment_n you_o will_v have_v a_o account_n hereafter_o how_o contraction_n may_v cause_v sweat_n
by_o squeeze_v in_o some_o case_n and_o stop_v it_o by_o shut_v the_o pore_n in_o other_o case_n 10._o it_o be_v by_o it_o that_o contraction_n that_o fear_v cold_a etc._n etc._n close_v the_o pore_n and_o repel_v the_o blood_n staunch_a bleed_a so_o happen_v also_o a_o great_a contraction_n of_o the_o pupil_n of_o the_o eye_n by_o the_o same_o cause_n 11._o it_o be_v the_o violence_n of_o this_o contraction_n upon_o fear_n terror_n pain_n cold_a etc._n etc._n close_v the_o small_a vessel_n of_o the_o animal_n spirit_n and_o thereby_o repel_v they_o cause_v the_o shiver_a in_o those_o case_n by_o the_o renitency_n of_o the_o elastic_a animal_n spirit_n spring_v back_o again_o toties_fw-la quoties_fw-la have_v gain_v more_o elastic_a force_n by_o the_o very_a compression_n itself_o which_o that_o contraction_n cause_n so_o that_o by_o reason_n of_o the_o dubious_a velitation_n or_o skirmish_v between_o the_o repel_v contraction_n and_o the_o spring_a spirit_n happen_v a_o tremulous_a motion_n as_o of_o quaver_v spring_n which_o shiver_a in_o ague-fits_a do_v former_o lead_v i_o to_o the_o situation_n of_o the_o cause_n of_o ague_n when_o i_o write_v my_o book_n de_fw-fr febribus_fw-la intermittentibus_fw-la in_o the_o angustiae_fw-la at_o the_o end_n of_o the_o vessel_n which_o terminate_v in_o the_o membrane_n the_o grievous_a sensation_n of_o which_o cause_v all_o the_o shiver_a that_o happen_v in_o any_o case_n to_o animal_n 12._o by_o the_o same_o contraction_n when_o very_o violent_a and_o of_o the_o whole_a body_n cold_a sweat_v happen_v in_o pain_n fear_v terror_n etc._n etc._n while_o it_o violent_o squeeze_v out_o the_o outmost_a and_o therefore_o cold_a moisture_n of_o our_o body_n as_o laundress_n do_v water_n out_o of_o wet_a linen_n by_o contortion_n thus_o if_o you_o dip_v one_o half_a of_o a_o wet_a cold_a sheet_n in_o hot_a water_n wrap_v the_o hot_a side_n within_o the_o cold_a or_o let_v a_o warm_a sheet_n that_o be_v contort_a cool_a on_o the_o outside_n of_o it_o and_o then_o wring_v it_o as_o woman_n do_v linen_n the_o water_n that_o first_o exudate_n will_v be_v cold_a for_o in_o this_o case_n the_o close_n of_o the_o pore_n avail_v nothing_o to_o hinder_v it_o as_o long_o as_o the_o express_a force_n master_n it_o more_o especial_o in_o animal_n body_n wherein_o the_o part_n be_v so_o contrive_v that_o humour_n design_v for_o exoretion_n can_v well_o return_v and_o therefore_o must_v upon_o contraction_n run_v out_o hence_o it_o be_v that_o alum_n or_o vitriol_n which_o be_v very_o astringent_a and_o therefore_o close_a the_o pore_n will_v notwithstanding_o cause_v the_o mouth_n or_o nose_n to_o run_v very_o plentiful_o with_o moisture_n by_o contract_v all_o the_o membrane_n about_o the_o mouth_n or_o nose_n and_o thereby_o squeeze_v out_o the_o moisture_n design_v to_o be_v excern_v which_o can_v return_v because_o the_o part_n be_v contrive_v against_o the_o return_n or_o readmittance_n thereof_o whereas_o alum_n or_o vitriol_n will_v staunch_v or_o stop_v blood_n by_o the_o same_o contraction_n because_o it_o may_v return_v as_o not_o be_v design_v to_o be_v excern_v either_o into_o the_o artery_n and_o so_o pass_v by_o other_o branch_n thereof_o or_o which_o be_v more_o ready_a and_o natural_a keep_v its_o course_n into_o the_o vein_n so_o the_o two_o riddle_n that_o i_o have_v know_v some_o proud_a physician_n amaze_v at_o though_o but_o trifle_n of_o alum_n and_o vitriol_n cause_v the_o spital_n etc._n etc._n to_o come_v out_o instead_o of_o stop_v it_o by_o their_o astringency_n and_o their_o stop_a blood_n at_o nose_n at_o the_o same_o time_n they_o cause_v the_o snot_n or_o other_o humour_n to_o run_v out_o be_v unfold_v 13._o it_o be_v by_o this_o mighty_a contraction_n grow_v to_o a_o enormous_a degree_n that_o the_o animal_n spirit_n be_v violent_o compress_v grow_v exceed_o irrequiete_a as_o upon_o convulsion_n in_o great_a pain_n or_o very_o grievous_a sensation_n at_o stomach_n etc._n etc._n while_o the_o sensitive_a soul_n compress_v they_o with_o mighty_a force_n and_o somewhat_o disorderly_a and_o uneven_o because_o of_o the_o confusion_n and_o hurry_n he_o be_v in_o to_o relieve_v the_o animal_n they_o by_o their_o springiness_n fling_v up_o and_o down_o with_o great_a vigour_n this_o make_v convulsive_a motion_n have_v great_a strength_n 14._o the_o body_n under_o this_o contraction_n be_v manifest_o shrink_v by_o measure_n especial_o when_o the_o sensation_n be_v very_o grievous_a but_o most_o of_o all_o if_o they_o cause_v a_o general_a convulsion_n which_o i_o manifest_o observe_v in_o a_o little_a bitch_n that_o be_v convulsive_a all_o over_o for_o three_o hour_n and_o be_v just_a expire_n when_o i_o give_v she_o the_o sal_fw-la volat._n oleo_n of_o opium_n which_o perfect_o restore_v she_o by_o relax_v the_o vessel_n some_o may_v think_v it_o strange_a that_o nature_n shall_v contrive_v a_o more_o nice_a and_o smart_a sensation_n which_o the_o contraction_n of_o the_o vessel_n of_o the_o animal_n spirit_n must_v cause_v by_o compress_v they_o etc._n etc._n in_o pain_n and_o by_o it_o which_o become_v so_o much_o the_o more_o acute_a whereas_o one_o will_v judge_v that_o nature_n will_v rather_o contrive_v its_o ease_n than_o improve_v its_o smart_n you_o be_v to_o know_v that_o the_o pain_n be_v in_o order_n to_o relieve_v the_o animal_n by_o exciting_a all_o its_o power_n to_o defend_v expel_v or_o reject_v the_o cause_n and_o that_o without_o a_o grievous_a sensation_n the_o sensitive_a soul_n be_v neither_o mind_v nor_o excite_v to_o do_v it_o and_o the_o more_o the_o pain_n be_v the_o more_o it_o be_v stir_v up_o to_o self-preservation_n and_o as_o be_v show_v the_o more_o vigorous_a do_v its_o motion_n grow_v by_o the_o compression_n of_o the_o elastic_a spirit_n to_o perform_v that_o work_n so_o nature_n not_o regard_v the_o pain_n which_o be_v rather_o for_o good_a as_o much_o as_o take_v away_o the_o cause_n advance_v that_o for_o this_o purpose_n like_o a_o wise_a physician_n who_o find_v a_o grievance_n at_o stomach_n not_o sufficient_a to_o excite_v effectual_a vomit_v to_o throw_v away_o the_o grieve_v cause_n add_v to_o the_o grievance_n by_o give_v a_o vomit_n which_o because_o as_o be_v say_v nature_n be_v proportionable_o excite_v to_o and_o invigorate_v for_o self-preservation_n sufficient_o solicit_v and_o enable_v it_o by_o a_o strong_a contraction_n to_o reject_v the_o grieve_v matter_n as_o the_o great_a the_o relaxation_n be_v the_o more_o be_v the_o rest_n of_o all_o part_n and_o the_o weak_a the_o animal_n spirit_n because_o less_o compress_v the_o gentle_a be_v all_o motion_n as_o you_o see_v in_o sleep_n consequent_o the_o less_o be_v the_o expense_n of_o spirit_n so_o that_o in_o sleep_n we_o generate_v more_o than_o we_o spend_v and_o be_v thereby_o recruit_v so_o the_o more_o the_o contraction_n be_v the_o more_o violent_a be_v the_o motion_n of_o the_o heart_n intestine_n and_o of_o all_o part_n and_o consequent_o the_o expense_n of_o spirit_n be_v the_o great_a therefore_o it_o can_v be_v no_o wonder_n that_o contraction_n do_v cause_n great_a commotion_n of_o spirit_n diary_n fever_n etc._n etc._n when_o you_o consider_v 1._o that_o the_o sensitive_a soul_n be_v by_o the_o grievous_a sensation_n etc._n etc._n that_o cause_n they_o put_v upon_o a_o great_a fret_v concern_v and_o hurry_v to_o defend_v the_o animal_n and_o lay_v about_o he_o all_o manner_n of_o way_n for_o self-preservation_n 2._o that_o the_o animal_n spirit_n be_v by_o mean_n of_o great_a compression_n cause_v by_o the_o defensive_a contraction_n in_o a_o very_a forcible_a springiness_n which_o cause_v all_o the_o action_n that_o be_v continual_a involuntary_a and_o of_o course_n to_o be_v perform_v with_o great_a violence_n proportionable_a to_o its_o compress_a elasticity_n beside_o that_o 3._o the_o systole_n of_o the_o heart_n be_v oftener_o repeat_v all_o which_o conspire_v to_o cause_v great_a commotion_n upon_o grievous_a sensation_n whereby_o diary_n fever_n etc._n etc._n be_v cause_v which_o be_v easy_o and_o natural_o cure_v by_o sleep_n or_o relaxation_n at_o present_a compose_v and_o quiet_v those_o perturbation_n who_o know_v though_o it_o be_v not_o my_o business_n to_o discuss_v it_o at_o present_a but_o that_o the_o contraction_n in_o the_o cold_a fit_n of_o ague_n have_v a_o great_a hand_n in_o cause_v the_o hot_a one_o how_o otherwise_o shall_v opium_n by_o only_o take_v away_o the_o grievous_a sensation_n of_o the_o cold_a fit_n take_v off_o or_o prevent_v the_o hot_a fit_n also_o but_o of_o this_o in_o my_o often-mentioned_n tract_n though_o not_o so_o often_o as_o it_o grieve_v i_o that_o it_o be_v not_o publish_v how_o reasonable_o may_v we_o now_o expect_v that_o pleasant_a sensation_n may_v cause_v quite_o contrary_a effect_n to_o that_o of_o grievous_a sensation_n viz._n relaxation_n and_o all_o its_o effect_n
only_o the_o open_n of_o the_o pore_n so_o that_o i_o need_v add_v no_o more_o word_n about_o it_o for_o the_o fame_n cause_o must_v have_v the_o same_o effect_n therefore_o a_o intense_a and_o permanent_a pleasure_n must_v have_v all_o or_o much_o of_o the_o effect_n of_o sleep_n in_o general_n as_o have_v be_v show_v it_o can_v therefore_o be_v any_o wonder_n that_o opium_n cause_v sleep_n yet_o be_v there_o difference_n between_o sleep_n and_o pleasure_n upon_o other_o account_n though_o not_o upon_o the_o account_n of_o relaxation_n viz._n because_o 1._o that_o sleep_n require_v also_o a_o rest_n of_o spirit_n or_o the_o sensitive_a soul_n whereas_o relaxation_n by_o pleasure_n be_v consistent_a with_o motion_n of_o the_o spirit_n either_o by_o outward_a action_n or_o internal_a motion_n thereof_o by_o some_o inward_a cause_n hence_o it_o be_v first_o that_o we_o can_v labour_v travel_v dance_n etc._n etc._n and_o enjoy_v pleasure_n and_o its_o relaxation_n volantary_a motion_n which_o require_v only_o a_o particular_a contraction_n of_o some_o part_n by_o the_o dictate_v of_o the_o will_n or_o appetite_n be_v consistent_a with_o the_o general_a relaxation_n by_o reason_n of_o the_o prerogative_n of_o the_o will._n thus_o do_v we_o move_v though_o more_o relax_v or_o when_o most_o merry_a and_o please_v with_o wine_n nay_o some_o will_v walk_v in_o their_o sleep_n when_o extreme_o intâ—t_v upon_o a_o thing_n as_o when_o awake_a which_o show_v the_o roll_a power_n of_o intentive_a contraction_n that_o may_v be_v exercise_v with_o relaxation_n and_o other_o contraction_n as_o the_o will_n itself_o may_v or_o intentive_a appetite_n second_o that_o pain_n be_v often_o take_v away_o by_o opium_n by_o the_o diversion_n and_o relaxation_n cause_v by_o pleasure_n and_o its_o inconsistence_n with_o pain_n without_o sleep_n which_o require_v the_o aforesaid_a rest_n that_o bare_a relaxation_n as_o such_o do_v not_o include_v though_o relaxation_n suffice_v to_o take_v away_o pain_n three_o that_o opium_n do_v by_o its_o heat_n active_a particle_n etc._n etc._n hinder_v some_o person_n to_o sleep_n yet_o have_v you_o in_o both_o these_o last_o case_n all_o other_o effect_n of_o opium_n as_o pleasure_n indolence_n relaxation_n etc._n etc._n which_o show_v how_o far_o sleep_v be_v from_o be_v a_o constant_a and_o the_o most_o genuine_a effect_n of_o opium_n as_o be_v general_o imagine_v however_o we_o must_v allow_v it_o as_o have_v be_v show_v to_o be_v a_o mighty_a disposer_n of_o we_o towards_o sleep_n because_o of_o the_o relaxation_n that_o it_o cause_n which_o be_v the_o main_a requisite_a of_o sleep_n ii_o that_o pleasure_n do_v without_o nutritive_a refection_n by_o the_o complacency_n it_o cause_v in_o the_o sensitive_a soul_n produce_v comfort_n satisfaction_n composure_n elevation_n of_o the_o spirit_n euphory_n etc._n etc._n of_o which_o sleep_n be_v either_o not_o at_o all_o capable_a or_o but_o in_o a_o low_a degree_n proportionable_a to_o the_o sensation_n that_o it_o have_v which_o be_v but_o little_a however_o a_o pleasure_n that_o remain_v within_o we_o even_o in_o our_o sleep_n as_o that_o of_o opium_n may_v well_o cause_v pleasant_a dream_n etc._n etc._n the_o reader_n may_v observe_v that_o in_o all_o place_n where_o i_o mention_v that_o relaxation_n cause_v the_o open_n of_o the_o pore_n that_o i_o speak_v only_o of_o perspiration_n as_o the_o effect_n thereof_o without_o mention_v sweat_n 1._o because_o perspiration_n be_v the_o only_a constant_a and_o infallible_a effect_n thereof_o by_o reason_n that_o the_o levity_n of_o the_o fume_n cause_v they_o as_o certain_o to_o pass_v at_o the_o pore_n when_o open_a as_o smoke_n pass_v up_o at_o a_o open_a chimney_n 2._o because_o sweat_n be_v a_o uncertain_a effect_n thereof_o for_o it_o require_v that_o the_o body_n be_v well_o fill_v with_o moisture_n though_o there_o be_v a_o relaxation_n or_o open_v of_o the_o pore_n as_o hypocrates_n very_o right_o intimate_v in_o that_o aphorism_n of_o his_o that_o i_o cite_v in_o the_o last_o chapter_n 1._o because_o sweat_n have_v not_o that_o levity_n that_o the_o fume_n have_v to_o cause_v it_o ready_o to_o move_v as_o soon_o as_o the_o pore_n be_v open_a 2._o because_o relaxation_n be_v more_o apt_a to_o receive_v detain_v and_o suspend_v humour_n 3._o because_o the_o protrusive_a motion_n of_o the_o heart_n be_v weak_a in_o all_o relaxation_n and_o all_o see_v how_o much_o its_o vigorous_a protrusion_n contribute_v to_o sweat_v upon_o action_n 4._o because_o a_o heartful_a of_o blood_n do_v not_o make_v such_o a_o push_v forward_o when_o the_o artery_n be_v widen_v by_o relaxation_n 5._o sweat_n have_v more_o of_o continuity_n consistence_n and_o viscidity_n can_v flow_v out_o so_o ready_o at_o the_o pore_n as_o a_o mere_a vapour_n however_o if_o the_o body_n be_v full_a of_o moisture_n and_o the_o pore_n open_a there_o be_v a_o natural_a course_n that_o way_n and_o the_o heart_n continual_o protrude_a it_o far_o and_o far_o a_o sweat_n follow_v and_o that_o whether_o they_o sleep_v or_o not_o 3._o because_o sweat_v as_o be_v in_o some_o sort_n intimate_v be_v sometime_o cause_v by_o the_o strong_a protrusion_n of_o the_o heart_n as_o in_o motion_n etc._n etc._n and_o upon_o that_o account_n come_v more_o under_o the_o title_n of_o flux_n cause_v by_o contraction_n than_o relaxation_n of_o which_o perspiration_n be_v a_o constant_a effect_n 4._o because_o sweat_n be_v sometime_o cause_v by_o another_o sort_n of_o contraction_n viz._n the_o compression_n of_o the_o whole_a body_n by_o a_o violent_a defensive_a contraction_n as_o in_o great_a terror_n agony_n and_o the_o like_a cause_v thereby_o as_o be_v show_v by_o the_o comparison_n of_o a_o wet_a sheet_n wring_v who_o out_o side_n be_v cold_a a_o cold_a sweat_n which_o that_o of_o alum_n or_o vitriol_n cause_v a_o exudation_n of_o the_o spital_n into_o the_o mouth_n by_o constr_v the_o part_n do_v illustrate_v very_o plain_o therefore_o you_o see_v i_o have_v just_a cause_n not_o to_o mention_v sweat_n as_o a_o certain_a and_o proper_a effect_n of_o relaxation_n without_o good_a distinction_n first_o make_v though_o unwary_a author_n that_o talk_v any_o thing_n one_o after_o another_o not_o know_v what_o they_o say_v make_v it_o their_o common_a say_n that_o sleep_n and_o opium_n stop_v all_o flux_n but_o sweat_n whereas_o they_o shall_v have_v rather_o say_v but_o perspiration_n for_o opium_n and_o sleep_n also_o will_v sometime_o hinder_v sweat_n viz._n that_o from_o pain_n terror_n etc._n etc._n and_o that_o as_o happen_v just_a upon_o awake_v by_o the_o strong_a systole_n of_o the_o heart_n and_o contraction_n of_o the_o whole_a body_n and_o that_o also_o upon_o motion_n unless_o the_o body_n be_v as_o be_v say_v full_a of_o humour_n or_o moisture_n therefore_o it_o be_v a_o vulgar_a error_n to_o say_v sweat_n instead_o of_o perspiration_n in_o the_o case_n aforesaid_a you_o may_v remember_v that_o in_o the_o beginning_n of_o this_o chapter_n i_o conclude_v that_o a_o sal-volatile-oleosum_a such_o as_o semen_n humanum_fw-la wherein_o the_o oily_a and_o volatile_a part_n be_v strict_o combine_v and_o the_o volatile_a somewhat_o more_o active_a or_o acrimonious_a than_o that_o in_o our_o membrane_n in_o general_a must_v be_v most_o please_v to_o the_o membrane_n by_o a_o fine_a titillation_n etc._n etc._n therefore_o if_o opium_n shall_v prove_v to_o be_v such_o we_o need_v not_o wonder_v at_o its_o titillate_v to_o venery_n nor_o indeed_o its_o cause_v a_o high_a sense_n of_o pleasure_n upon_o any_o membrane_n they_o be_v all_o of_o the_o same_o nature_n but_o especial_o upon_o the_o most_o exquisite_o dispose_v membrane_n of_o the_o stomach_n and_o the_o venereal_a part_n nor_o consequent_o its_o cause_v all_o the_o aforementioned_a effect_n of_o intense_a pleasure_n as_o comfort_n satisfaction_n ovation_n etc._n etc._n of_o the_o sensitive_a soul_n or_o spirit_n and_o relaxation_n of_o all_o the_o sensile_a part_n which_o will_v easy_o solve_v all_o the_o phenomenas_n of_o opium_n however_o numerous_a mysterious_a and_o seem_o contradictory_n as_o you_o will_v find_v let_v we_o therefore_o now_o see_v whether_o opium_n be_v such_o a_o sal-volatile-oleosum_a wherein_o the_o volatile_a particle_n be_v somewhat_o more_o active_a or_o acrimonious_a than_o we_o and_o the_o oily_a and_o volatile_a part_n strict_o combine_v if_o so_o the_o business_n be_v do_v the_o nail_n be_v hit_v on_o the_o head_n and_o i_o may_v say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d chap._n xv._o show_v what_o be_v the_o principle_n of_o opium_n and_o which_o cause_n the_o good_a and_o bad_a effect_n thereof_o have_v try_v if_o not_o tire_v your_o patience_n and_o premise_v what_o i_o think_v necessary_a in_o the_o forego_n chapter_n i_o now_o reassume_v the_o thread_n of_o my_o discourse_n as_o for_o the_o passive_a principle_n of_o opium_n which_o do_v or_o signify_v little_a or_o nothing_o
contraction_n by_o which_o vomit_v be_v perform_v 4._o it_o still_v hiccough_n for_o the_o same_o reason_n 5._o it_o cause_v convulsion_n and_o contraction_n to_o cease_v 1._o because_o it_o induce_v a_o relaxation_n which_o take_v they_o off_o 2._o by_o take_v off_o the_o sense_n which_o the_o irritate_v cause_n 3._o by_o compose_v the_o spirit_n 6._o it_o cause_v the_o meat_n to_o stay_v long_o at_o stomach_n as_o sleep_n do_v 1._o by_o relax_v the_o stomach_n so_o that_o it_o be_v not_o subject_a to_o contract_v to_o send_v it_o out_o 2._o by_o still_v all_o motion_n whereby_o the_o stomach_n grow_v proportionable_o unactive_a 3._o because_o the_o relaxation_n oppose_v the_o contraction_n by_o which_o the_o menstruum_fw-la be_v send_v into_o the_o stomach_n or_o the_o saliva_n into_o the_o mouth_n both_o which_o be_v therefore_o much_o want_v in_o sleep_n for_o the_o like_a reason_n as_o have_v be_v show_v 7._o it_o moderate_v and_o prevent_v hunger_n 1._o because_o as_o be_v say_v the_o menstruum_fw-la be_v not_o so_o plentiful_o send_v or_o squeeze_a into_o the_o relaxed_a stomach_n 2._o because_o it_o take_v away_o the_o sense_n of_o hunger_n 3._o because_o it_o leave_v the_o meat_n to_o stay_v too_o long_o at_o stomach_n by_o reason_n that_o it_o be_v relax_v more_o insensible_a and_o proportionable_o languid_a in_o motion_n as_o in_o sleep_n 8._o it_o cause_v sweat_v when_o the_o body_n be_v full_a of_o moisture_n as_o sleep_n do_v by_o relax_v and_o thereby_o open_v the_o pore_n and_o not_o as_o people_n common_o talk_v by_o attenuate_v and_o the_o like_a for_o a_o grain_n of_o opium_n bear_v no_o proportion_n to_o the_o blood_n and_o humour_n that_o it_o cause_v it_o mere_o as_o sleep_n do_v be_v manifest_a not_o only_o because_o it_o bear_v not_o a_o due_a proportion_n to_o the_o work_n as_o a_o alterative_a but_o because_o man_n do_v not_o sweat_v in_o that_o case_n as_o in_o sleep_n without_o much_o moisture_n in_o the_o body_n whereas_o much_o will_v not_o be_v attenuate_v as_o soon_o as_o less_o therefore_o it_o be_v only_o a_o exudation_n of_o the_o humour_n upon_o a_o plenty_n thereof_o and_o open_v of_o the_o pore_n sanctorius_n sect._n 1_o aph._n 22._o invisibilis_fw-la perspiratio_fw-la fit_a visibilis_fw-la quando_fw-la nutrimentum_fw-la est_fw-la nimium_fw-la that_o be_v invisible_a perspiration_n become_v visible_a sweat_n when_o nourishment_n or_o moisture_n be_v too_o much_o which_o exact_o agree_v with_o that_o of_o hypocrates_n cite_v in_o chap._n 13._o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d etc._n etc._n 9_o it_o cause_v the_o menses_fw-la to_o flow_v when_o nothing_o be_v want_v but_o the_o open_n or_o relax_v of_o the_o viae_fw-la or_o pore_n they_o issue_v out_o at_o as_o when_o they_o be_v natural_o too_o narrow_a and_o close_a as_o upon_o the_o first_o tendency_n to_o they_o in_o young_a girl_n or_o when_o stop_v by_o reason_n of_o any_o undue_a contraction_n thereof_o as_o by_o pain_n cold_a sorrow_n or_o other_o grievous_a passion_n all_o which_o do_v close_o the_o pore_n beside_o it_o do_v irritate_fw-la those_o very_a sensile_a venereal_a part_n to_o erection_n and_o i_o have_v reason_n to_o think_v that_o it_o do_v by_o a_o general_a relaxation_n cause_n a_o increase_n of_o blood_n as_o it_o do_v of_o the_o breast_n milk_n etc._n etc._n cause_v as_o it_o be_v a_o artificial_a puberty_n or_o at_o least_o much_o promote_a the_o natural_a and_o therefore_o be_v of_o excellent_a use_n in_o this_o case_n in_o judicious_a hand_n though_o little_a thought_n of_o in_o practice_n obj._n here_o i_o may_v be_v sure_a of_o a_o objection_n that_o it_o stop_v all_o flux_n but_o sweat_v or_o perspiration_n ans._n it_o be_v as_o false_a as_o it_o be_v a_o common_a say_n if_o they_o do_v not_o mean_v only_o such_o flux_n as_o proceed_v from_o grievous_a sensation_n and_o contraction_n thereupon_o for_o how_o can_v that_o which_o relax_n all_o part_n stop_v any_o flux_n that_o depend_v upon_o relaxation_n as_o stillicidium_fw-la urinae_fw-la by_o relaxation_n of_o the_o sphincter_n of_o the_o â—ladder_n involuntary_a flux_n per_fw-la anum_fw-la by_o the_o 〈◊〉_d of_o its_o sphincter_n and_o such_o like_a so_o do_v i_o speak_v of_o a_o flux_n that_o may_v often_o depend_v upon_o relaxation_n as_o i_o have_v show_v obj._n but_o it_o may_v be_v object_v that_o it_o particular_o stanche_n blood_n how_o then_o shall_v it_o promote_v the_o menses_fw-la ans._n experience_n tell_v i_o it_o do_v and_o reason_n confirm_v it_o it_o stanche_n blood_n by_o compose_v the_o fury_n of_o its_o motion_n but_o that_o do_v not_o hinder_v but_o it_o may_v relax_v the_o pore_n for_o sweat_n menses_fw-la lochia_n etc._n etc._n to_o pass_v and_o why_o not_o for_o the_o menses_fw-la and_o lochia_n as_o well_o as_o sweat_v by_o open_v the_o pore_n i_o will_v fain_o know_v consider_v also_o the_o titillation_n that_o it_o cause_n upon_o those_o venereal_a part_n which_o may_v very_o much_o solicit_v their_o motion_n 10._o it_o cause_v the_o lochia_n to_o flow_v for_o the_o same_o reason_n that_o it_o do_v the_o menses_fw-la this_o i_o have_v great_a experience_n in_o note_v that_o the_o menses_fw-la lochia_n and_o perspiration_n be_v natural_a evacuation_n that_o have_v pore_n design_v for_o they_o by_o nature_n the_o open_n of_o which_o by_o relaxation_n must_v make_v way_n for_o they_o suppose_v when_o the_o blood_n flow_v so_o much_o into_o the_o skin_n as_o to_o cause_v a_o efflorescence_n by_o the_o relaxation_n thereof_o after_o opium_n be_v take_v that_o there_o be_v pore_n to_o carry_v out_o blood_n as_o there_o be_v for_o sweat_n why_o shall_v not_o one_o flow_v as_o well_o as_o the_o other_o but_o there_o be_v such_o pore_n for_o the_o menses_fw-la and_o lochia_n and_o large_a one_o too_o and_o therefore_o it_o must_v promote_v they_o and_o why_o shall_v not_o relaxation_n do_v it_o as_o well_o as_o contraction_n by_o cold_a terror_n grief_n etc._n etc._n stop_v they_o for_o the_o effect_n of_o contrary_n be_v contrary_a 11._o it_o cause_v the_o stone_n to_o pass_v 1._o because_o it_o reâ—_n and_o so_o widen_v the_o passage_n 2._o because_o it_o 〈◊〉_d move_v with_o little_a or_o no_o pain_n which_o contract_v the_o part_n and_o so_o hinder_v its_o passage_n therefore_o the_o use_n of_o opium_n with_o some_o other_o help_v be_v the_o great_a mean_n that_o can_v be_v or_o ever_o will_v be_v for_o the_o stone_n till_o the_o dissolution_n of_o it_o be_v find_v out_o not_o only_o to_o give_v ease_n in_o the_o case_n of_o the_o stone_n but_o to_o cause_v it_o to_o pass_v for_o both_o which_o purpose_v it_o excel_v all_o thing_n and_o do_v both_o at_o once_o 12._o it_o cause_v the_o delivery_n of_o woman_n by_o relax_v the_o neck_n of_o the_o womb_n as_o it_o do_v that_o of_o the_o bladder_n to_o deliver_v person_n of_o the_o stone_n but_o in_o the_o delivery_n of_o woman_n it_o be_v not_o to_o be_v use_v but_o in_o particular_a case_n and_o by_o a_o very_a skilful_a hand_n 1._o because_o it_o be_v apt_a to_o take_v off_o all_o the_o woman_n pain_n and_o throw_v and_o so_o quite_o disappoint_v the_o delivery_n for_o a_o day_n 2_o 3_o 4_o or_o more_o sometime_o 2._o because_o it_o cause_v a_o great_a relaxation_n the_o part_n after_o delivery_n will_v be_v very_o unapt_a to_o close_v and_o contract_v due_o as_o they_o shall_v in_o such_o case_n otherwise_o several_a inconvenience_n may_v ensue_v 3._o it_o may_v be_v pernicious_a upon_o the_o account_n of_o the_o evacuation_n of_o blood_n that_o then_o happen_v but_o these_o thing_n belong_v more_o proper_o to_o the_o use_v of_o opium_n in_o cure_n 13._o it_o cause_v deadness_n of_o the_o eye_n as_o in_o drunkeness_n etc._n etc._n because_o the_o cornea_n be_v relax_v so_o that_o the_o humour_n do_v not_o fill_v it_o up_o to_o a_o tense_n rotundity_n as_o when_o it_o be_v more_o contract_v 14._o it_o cause_v the_o pupilla_fw-la to_o dilate_v because_o of_o the_o same_o relaxation_n 15._o it_o cause_v a_o growth_n of_o the_o breast_n penis_n and_o increase_v of_o milk_n by_o reason_n of_o the_o same_o relaxation_n as_o the_o pleasure_n of_o the_o semen_n upon_o puberty_n do_v or_o as_o emollient_n and_o relaxer_n apply_v to_o the_o breast_n increase_v milk_n etc._n etc._n by_o make_v more_o room_n for_o it_o etc._n etc._n 16._o it_o cause_v venereal_a dream_n because_o of_o the_o titillation_n of_o the_o venereal_a membrane_n that_o it_o cause_n 17._o it_o cause_v nocturnal_a pollution_n for_o the_o same_o reason_n and_o because_o it_o relax_n the_o part_n 18._o it_o cause_v itch_n in_o the_o skin_n because_o of_o its_o titillation_n by_o its_o volatile_a salt_n 19_o it_o cause_v much_o urine_n as_o cantbaride_n bee_n pismire_n millepedes_n etc._n etc._n do_v by_o its_o volatile_a salt_n which_o titillate_n and_o irritate_v those_o
part_n by_o its_o relax_v the_o pore_n of_o the_o kidney_n and_o render_v the_o humour_n more_o penetrate_v in_o some_o measure_n by_o the_o volatile_a salt_n 20._o it_o cause_v a_o nausea_n by_o its_o rosin_n stick_v to_o and_o teaze_v the_o sensile_a coat_n of_o the_o stomach_n the_o reason_n why_o it_o be_v general_o so_o long_o before_o it_o cause_v a_o nausea_n or_o vomit_v be_v that_o its_o pleasure_n do_v at_o first_o prevent_v it_o till_o at_o last_o the_o stick_a rosin_n urge_v it_o by_o its_o long_a stay_n and_o vexatious_a adherence_n 21._o it_o cause_v swimmings_n in_o the_o head_n by_o consent_n when_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o you_o find_v upon_o nauseas_fw-la before_o vomit_v or_o when_o any_o thing_n do_v much_o offend_v the_o stomach_n as_o much_o drink_n or_o wine_n which_o when_o they_o have_v vomit_v those_o swimming_n cease_v 22._o it_o cause_v watch_v in_o some_o person_n who_o be_v of_o very_o movable_a spirit_n by_o actuate_a and_o stir_v their_o spirit_n by_o its_o active_a volatile_a salt_n though_o it_o do_v at_o the_o same_o time_n please_v the_o membrane_n and_o consequent_o relax_v the_o sensile_a part_n and_o thereby_o cause_n indolence_n the_o effect_n of_o relaxation_n which_o it_o also_o do_v when_o people_n keep_v themselves_o from_o sleep_n by_o voluntary_a motion_n and_o therefore_o take_v away_o pain_n even_o when_o man_n travel_v etc._n etc._n beside_o there_o be_v some_o sort_n of_o person_n that_o upon_o joy_n good_a news_n pleasure_n or_o the_o like_a be_v too_o much_o elevate_v or_o have_v a_o restless_a ovation_n of_o the_o spirit_n which_o will_v not_o suffer_v they_o to_o sleep_n though_o they_o be_v in_o a_o pleasant_a condition_n all_o the_o time_n this_o may_v be_v the_o case_n of_o some_o that_o can_v sleep_v after_o opium_n though_o they_o be_v all_o the_o time_n as_o they_o call_v it_o in_o a_o heavenly_a condition_n for_o as_o i_o have_v say_v a_o quietness_n of_o the_o spirit_n be_v requisite_a to_o cause_v sleep_n as_o well_o as_o relaxation_n but_o relaxation_n alone_o and_o thereby_o expansion_n of_o the_o spirit_n so_o that_o they_o can_v carry_v impression_n smart_o be_v sufficient_a to_o cause_v indolence_n and_o the_o pleasure_n to_o cause_v a_o heavenly_a or_o very_o pleasant_a condition_n sanctor_n stat._n med._n sect._n 7._o aph._n 28._o say_v that_o laetitia_n perseverans_fw-la per_fw-la multos_fw-la dies_fw-la somnum_fw-la impedit_fw-la persevere_v pleasure_n may_v do_v the_o same_o by_o like_a reason_n that_o be_v too_o much_o 〈◊〉_d or_o ovation_n of_o the_o spirit_n sometime_o too_o large_a a_o do_v cause_n watch_v by_o over-actuating_a and_o exciting_a the_o spirit_n medicum_fw-la vini_fw-la generosi_fw-la &_o allium_fw-la say_v sanctorius_n conciliant_fw-la somnum_fw-la &_o perspirationem_fw-la si_fw-la vero_fw-la plus_fw-la justo_fw-la sumantur_fw-la utrumque_fw-la prohibent_fw-la perspirabile_fw-la tamen_fw-la in_o sudorem_fw-la convertunt_fw-la that_o be_v a_o little_a generous_a wine_n and_o garlic_n will_v cause_v sleep_n and_o perspiration_n but_o too_o much_o hinder_v both_o yet_o they_o convert_v the_o perspirable_a matter_n to_o a_o sweat_n which_o wine_n and_o garlick_n have_v the_o nature_n of_o opiate_n and_o the_o reason_n why_o they_o sweat_v be_v the_o quantity_n of_o the_o wine_n afford_v more_o moisture_n hypocrates_n say_v 23._o a_o dubious_a state_n between_o sleep_v and_o wake_v be_v cause_v when_o the_o relaxation_n upon_o the_o pleasure_n of_o opium_n incline_v to_o sleep_v but_o the_o irreâ—uiete_a ovation_n of_o the_o spirit_n by_o the_o pleasure_n and_o titillation_n will_v hardly_o suffer_v it_o yet_o high_o please_v and_o put_v they_o in_o a_o sweet_a agreeable_a condition_n chap._n xix_o the_o explication_n of_o the_o rare_a effect_n of_o opium_n in_o a_o moderate_a do_v 1._o it_o cause_v temporary_a pulse_n of_o the_o 〈◊〉_d and_o sometime_o of_o other_o part_n by_o its_o over_o relax_v the_o part_n and_o cause_v thereby_o a_o expansion_n of_o the_o elastic_a spirit_n which_o as_o be_v demonstrate_v weaken_v their_o motion_n 2._o falter_v of_o the_o tongue_n do_v as_o in_o relaxation_n by_o drunkenness_n proceed_v from_o the_o same_o cause_n 3._o looseness_n of_o the_o low_a jaw_n as_o you_o see_v in_o the_o drowsy_a and_o drunken_a people_n be_v from_o the_o same_o relaxation_n 4._o it_o sometime_o prevent_v sweat_n by_o cause_v a_o very_a liberal_a perspiration_n as_o be_v show_v for_o as_o sanctorius_n say_v who_o shall_v know_v it_o much_o insensible_a perspiration_n and_o sweat_n can_v consist_v especial_o in_o a_o temperate_a person_n who_o eat_v and_o drink_v moderate_o therefore_o if_o you_o keep_v a_o person_n that_o sweat_v much_o at_o night_n in_o a_o free_a perspiration_n all_o day_n by_o the_o help_n of_o a_o opiate_n you_o will_v much_o lessen_v or_o total_o prevent_v the_o sweat_n at_o night_n as_o in_o consumptive_a person_n etc._n etc._n 5._o it_o cause_v abortion_n by_o relax_v the_o neck_n of_o the_o womb_n which_o also_o the_o pleasure_n of_o coition_n sometime_o do_v for_o the_o like_a reason_n and_o will_v be_v much_o more_o apt_a to_o cause_v it_o if_o it_o continue_v long_o as_o that_o of_o opium_n do_v note_v the_o inconvenience_n of_o coition_n after_o impregnation_n this_o be_v the_o great_a cause_n that_o whore_n be_v not_o apt_a to_o bear_v child_n because_o frequency_n of_o pleasure_n do_v over-relax_a the_o collum_n 〈◊〉_d 6._o it_o prevent_v abortion_n when_o fear_n terror_n or_o any_o contract_a cause_n as_o grief_n grievous_a passion_n or_o sensation_n do_v threaten_v it_o by_o its_o take_n off_o the_o contraction_n and_o grievance_n that_o cause_v it_o 7_o intumescence_n of_o the_o lip_n be_v from_o their_o relaxation_n admit_v the_o blood_n and_o humour_n into_o they_o in_o a_o plentiful_a manner_n beside_o that_o their_o laxity_n and_o the_o inadvertency_n occasion_v by_o the_o divert_v pleasure_n or_o drowsiness_n that_o follow_v let_v the_o low_a lip_n hang_v down_o careless_o as_o be_v usual_a in_o such_o case_n may_v by_o expose_v much_o more_o of_o that_o lip_n which_o be_v most_o concern_v in_o this_o effect_n make_v it_o seem_v large_a as_o a_o hang_a lip_n do_v 8._o it_o may_v cure_v a_o dropsy_n as_o dr._n wâ—llis_n do_v instance_n 1._o by_o cause_v a_o free_a perspiration_n which_o be_v much_o want_v in_o those_o case_n 2._o by_o relax_v the_o pore_n and_o make_v way_n for_o the_o humour_n to_o 〈◊〉_d 3._o by_o cause_v much_o urine_n as_o cantharides_n millepedes_n &c_n &c_n do_v upon_o the_o account_n of_o their_o volatile-salt_n with_o which_o opium_n abound_v 9_o it_o cure_v stupor_n that_o proceed_v from_o contraction_n as_o by_o cold_a etc._n etc._n by_o relax_v all_o part_n 10._o it_o cause_v anxiety_n and_o distress_n by_o the_o rosin_n stick_v and_o teaze_v the_o stomach_n 11._o vomit_n and_o hiccough_n proceed_v from_o the_o same_o cause_n 12._o convulsion_n be_v cause_v by_o the_o same_o rosin_n while_o it_o continual_o urge_v the_o stomach_n to_o grievous_a vomit_n which_o at_o last_o draw_v other_o part_n as_o the_o stomach_n usual_o do_v when_o under_o great_a grievance_n into_o violent_a contraction_n or_o convulsion_n by_o consent_n to_o endeavour_v its_o assistance_n because_o the_o defensive_a contraction_n grow_v very_o high_a by_o the_o almost_o intolerable_a and_o tedious_a grievance_n at_o stomach_n cause_v a_o mighty_a compression_n of_o the_o springy_a animal_n spirit_n by_o which_o mean_v they_o grow_v very_o forcible_a irrequiete_a and_o violent_o springy_a under_o the_o urgency_n of_o a_o enormous_a compressure_n which_o cause_v such_o convulsive_a motion_n note_v that_o such_o a_o violent_a compression_n of_o the_o animal_n spirit_n into_o a_o great_a springiness_n be_v the_o cause_n of_o the_o strength_n of_o convulsive_a motion_n so_o that_o sometime_o a_o strong_a man_n can_v hardly_o hold_v a_o child_n limb_n in_o such_o case_n 13._o syncopes_fw-la leipothymy_n and_o faint_n follow_v when_o the_o sensitive_a soul_n be_v quite_o tire_v and_o overbear_v by_o the_o fatigue_n of_o such_o distress_n vomit_n and_o defensive_a contraction_n to_o reject_v and_o excuss_v the_o say_v adhere_v and_o teaze_v rosin_n yield_v itself_o to_o rest_n and_o let_v we_o go_v the_o reign_v of_o contraction_n as_o be_v fruitless_a and_o no_o long_o endurable_a whereupon_o all_o the_o sensile_a part_n be_v relax_v in_o the_o high_a degree_n they_o thereby_o grow_v unfit_a for_o sensation_n and_o the_o animal_n spirit_n expand_v as_o far_o as_o the_o atmospherical_a compressure_n permit_v they_o so_o that_o they_o grow_v incapable_a to_o convey_v impression_n by_o which_o mean_v sense_n fail_v and_o motion_n also_o for_o the_o same_o reason_n because_o the_o animal_n spirit_n loose_v their_o springy_a endeavour_n for_o want_n of_o a_o sufficient_a compression_n to_o render_v they_o flippant_a for_o the_o purpose_n which_o be_v the_o cause_n as_o in_o sleep_n that_o sense_n
and_o motion_n fail_v together_o of_o the_o great_a perspiration_n and_o all_o other_o effect_n of_o relaxation_n in_o such_o syncopes_fw-la or_o leipothymy_n in_o a_o yet_o high_o degree_n than_o in_o sleep_n wherein_o the_o sensitive_a soul_n do_v not_o quite_o let_v go_v the_o reign_v of_o contraction_n as_o appear_v by_o the_o motion_n that_o remain_v as_o of_o the_o heart_n intestine_n etc._n etc._n though_o far_o more_o remiss_a in_o sleep_n than_o in_o a_o wake_v state_n note_v that_o such_o leipothymy_n be_v as_o be_v hint_v of_o the_o same_o nature_n as_o sleep_n be_v but_o that_o they_o be_v sudden_a more_o profound_a and_o not_o so_o usual_a natural_a and_o of_o course_n as_o sleep_n be_v which_o make_v they_o more_o amaze_a and_o surprise_v therefore_o it_o follow_v that_o they_o be_v as_o sleep_n be_v a_o mean_n of_o recruit_v when_o all_o work_n and_o tug_v by_o defensive_a contraction_n fail_v and_o so_o the_o last_o refuge_n of_o the_o sensitive_a soul_n when_o overtired_n in_o order_n to_o recover_v strength_n for_o a_o fresh_a engagement_n with_o the_o enemy_n as_o be_v tire_v at_o night_n the_o sensitive_a soul_n loosen_v the_o rign_n of_o contraction_n to_o enable_v he_o the_o better_a to_o fall_v to_o his_o work_n the_o next_o day_n this_o you_o will_v find_v by_o all_o reason_n and_o experience_n to_o be_v the_o true_a state_n of_o leipothymy_n upon_o grievance_n and_o fatigue_n though_o not_o hitherto_o mind_v that_o i_o know_v of_o many_o true_a and_o useful_a consequence_n do_v hence_o follow_v as_o that_o we_o be_v not_o always_o to_o disturb_v they_o or_o put_v they_o out_o of_o these_o recruit_v leipothymy_n by_o grievous_a mean_n as_o pricking_n pinch_n etc._n etc._n but_o only_o by_o cordial_n and_o refresh_a thing_n as_o you_o will_v treat_v a_o person_n much_o tire_v or_o by_o let_v they_o take_v their_o nap_n if_o i_o may_v so_o call_v it_o if_o there_o be_v not_o very_o eminent_a danger_n but_o it_o be_v endless_a and_o beside_o my_o purpose_n to_o make_v a_o particular_a discourse_n of_o this_o matter_n which_o will_v belong_v more_o proper_o to_o my_o tract_n of_o animal_n mechanism_n 14._o death_n happen_v sometime_o though_o very_o rare_o and_o that_o in_o very_o weak_a people_n that_o take_v little_a or_o no_o sustenance_n because_o either_o when_o fall_v into_o such_o syncopes_fw-la they_o never_o come_v out_o of_o they_o by_o reason_n that_o they_o have_v not_o within_o they_o wherewith_o to_o recruit_v their_o spirit_n or_o that_o opium_n take_v they_o much_o spend_v and_o tire_v with_o distemper_n cause_n as_o in_o weak_a and_o weary_a people_n a_o most_o profound_a sopor_fw-la which_o not_o recruit_v they_o who_o take_v or_o digest_v no_o sustenance_n they_o must_v rather_o grow_v weak_a and_o weak_a for_o somewhat_o be_v spend_v while_o we_o live_v and_o consequent_o the_o sleep_n or_o sopor_fw-la more_o and_o more_o profound_a till_o they_o sleep_v their_o last_o for_o want_v of_o some_o recruit_v which_o be_v the_o very_a thing_n that_o natural_o lessen_v sleep_n and_o awake_v we_o when_o there_o be_v no_o other_o apparent_a cause_n for_o as_o the_o be_v tire_v and_o want_v of_o recruit_v cause_n sleep_v so_o the_o have_v it_o cause_v wake_v or_o which_o be_v the_o same_o in_o effect_n no_o far_o need_v of_o relaxation_n for_o recruit_n sake_n so_o that_o the_o sensitive_a soul_n fall_v to_o his_o useful_a work_n of_o vigilative_a contraction_n for_o sense_n and_o motion_n sake_n 15._o it_o sometime_o cause_n purge_v which_o happen_v as_o far_o as_o i_o have_v observe_v or_o can_v learn_v only_o when_o it_o be_v give_v in_o a_o good_a quantity_n to_o person_n of_o a_o strong_a digestion_n or_o canine_a appetite_n the_o case_n be_v thus_o when_o person_n that_o be_v of_o a_o strong_a digestion_n take_v a_o resinous_n opiate_n in_o good_a quantity_n they_o do_v in_o great_a measure_n by_o their_o fix_a salt_n at_o stomach_n and_o strong_a digestion_n subdue_v the_o volatility_n of_o the_o opium_n and_o dissolve_v its_o rosin_n which_o then_o as_o acrimonious_a rosin_n or_o vomit_n subdue_v by_o fix_a salt_n use_v to_o do_v cause_v purge_v hence_o it_o be_v that_o it_o general_o if_o not_o always_o purge_v dog_n and_o people_n of_o a_o high_a canine_a appetite_n and_o that_o sometime_o meet_v such_o fix_a salt_n it_o purge_v the_o consumptive_a bartholine_n say_v that_o mandrake_n juice_n purge_v when_o it_o meet_v with_o acrimonious_a fix_a salt_n erastus_n and_o quercelan_n do_v agree_v that_o it_o have_v a_o purgative_n quality_n but_o that_o it_o do_v not_o always_o exert_v it_o 1._o because_o it_o take_v away_o the_o sense_n of_o irritation_n 2._o because_o it_o be_v give_v in_o too_o small_a a_o quantity_n the_o reason_n be_v just_a and_o right_a and_o not_o only_o consistent_a with_o but_o confirm_v what_o i_o say_v note_v that_o this_o be_v not_o intend_v of_o the_o purge_v that_o happen_v after_o the_o declination_n of_o its_o operation_n which_o be_v as_o you_o will_v find_v from_o another_o cause_n therefore_o this_o do_v not_o smell_v of_o the_o opium_n as_o the_o other_o do_v because_o it_o be_v past_a and_o go_v before_o that_o in_o the_o declination_n happen_v of_o which_o more_o in_o its_o proper_a place_n 16._o it_o raise_v and_o revive_v some_o person_n that_o be_v almost_o expire_a in_o two_o case_n one_o be_v when_o such_o as_o have_v be_v use_v to_o take_v it_o be_v even_o expire_a for_o want_n of_o it_o of_o which_o more_o hereafter_o the_o other_o case_n be_v when_o violent_a contraction_n as_o from_o pain_n cold_a vomit_n and_o grievous_a passion_n as_o terror_n etc._n etc._n be_v the_o cause_n that_o people_n be_v almost_o expire_a for_o it_o take_v off_o the_o contraction_n by_o relax_v etc._n etc._n 17._o it_o stay_v very_o long_o at_o stomach_n when_o the_o rosin_n thereof_o stick_v to_o the_o stomach_n and_o be_v there_o detain_v beside_o that_o the_o stomach_n be_v relax_v and_o have_v little_a sense_n or_o motion_n as_o in_o sleep_n do_v not_o soon_o digest_v it_o or_o discharge_v it_o it_o be_v fine_a in_o this_o case_n and_o all_o other_o to_o observe_v how_o sensation_n and_o motion_n go_v hand_n in_o hand_n keep_v equal_a pace_n and_o equal_a proportion_n as_o it_o plain_o must_v be_v by_o the_o principle_n of_o relaxation_n and_o contraction_n which_o i_o have_v state_v and_o prove_v 18._o it_o cause_v stoppage_n of_o urine_n sometime_o especial_o in_o old_a people_n by_o over_o relax_v and_o cause_v a_o kind_n of_o a_o temporary_a palsy_n of_o the_o bladder_n as_o be_v show_v and_o take_v away_o the_o sense_n of_o the_o irritation_n of_o the_o urine_n which_o shall_v contract_v the_o bladder_n to_o squeeze_v it_o out_o by_o which_o mean_v it_o happen_v sometime_o that_o the_o bladder_n come_v to_o be_v so_o over_o extend_v beyond_o its_o due_a tone_n that_o they_o can_v contract_v it_o to_o make_v water_n in_o all_o which_o case_n strong_a contracter_n as_o cold_a terror_n etc._n etc._n immediate_o cure_v they_o the_o very_a put_v the_o scrotum_fw-la to_o the_o edge_n of_o a_o cold_a chamberpot_n have_v effect_v it_o several_a time_n by_o my_o advice_n though_o if_o need_v be_v you_o must_v come_v to_o dash_v of_o cold_a water_n upon_o the_o region_n of_o the_o bladder_n or_o pump_v on_o it_o or_o dip_v in_o it_o etc._n etc._n so_o terror_n and_o cause_v a_o very_a smart_n pain_n especial_o near_o those_o part_n will_v do_v much_o but_o cold_a be_v the_o ready_a and_o best_a remedy_n 19_o it_o sometime_o prove_v dangerous_a after_o great_a hemorrbage_n or_o evacuation_n as_o tapping_n in_o dropsy_n etc._n etc._n because_o the_o relaxation_n hinder_v the_o part_n due_o to_o contract_v upon_o what_o remain_v which_o may_v cause_v great_a mischief_n as_o discontinuation_n of_o motion_n etc._n etc._n thus_o have_v you_o all_o the_o constant_a frequent_a and_o rare_a effect_n of_o opium_n take_v internal_o in_o a_o moderate_a do_v so_o natural_o easy_o plain_o and_o mechanical_o explicate_v that_o people_n may_v in_o my_o judgement_n more_o admire_v how_o all_o fail_v of_o discover_v the_o manner_n of_o their_o production_n than_o that_o i_o find_v it_o as_o man_n be_v apt_a to_o think_v of_o the_o circulation_n of_o the_o blood_n which_o now_o as_o i_o hope_v the_o effect_n of_o opium_n do_v seem_v very_o obvious_a both_o which_o case_n be_v to_o i_o very_o strong_a argument_n of_o a_o be_v that_o rule_n and_o dispose_n darken_v and_o illuminate_v etc._n etc._n as_o he_o please_v when_o i_o consider_v that_o both_o the_o circulation_n of_o the_o blood_n and_o the_o cause_n of_o the_o operation_n of_o opium_n viz._n pleasure_n at_o stomach_n etc._n etc._n fall_v under_o the_o sense_n of_o many_o million_o who_o in_o one_o case_n see_v the_o blood_n move_v and_o in_o the_o other_o feel_v
the_o pleasure_n yet_o be_v neither_o discover_v for_o many_o thousand_o of_o year_n especial_o consider_v also_o that_o in_o the_o case_n of_o opium_n thousand_o of_o ingenious_a man_n have_v diligent_o inquire_v after_o the_o cause_n of_o its_o operation_n who_o make_v no_o far_a step_n in_o it_o then_o to_o state_n thing_n that_o have_v not_o as_o much_o as_o existence_n viz._n a_o cold_a quality_n and_o 〈◊〉_d fly_v from_o the_o stomach_n to_o the_o head_n to_o be_v the_o cause_n thereof_o therefore_o it_o be_v plain_a that_o neither_o be_v he_o that_o plant_n any_o thing_n neither_o he_o that_o water_v but_o god_n that_o give_v the_o increase_n of_o knowledge_n and_o of_o other_o thing_n to_o who_o be_v all_o glory_n chap._n xx._n the_o explication_n of_o the_o effect_n of_o the_o declination_n of_o the_o operation_n of_o opium_n in_o a_o moderate_a do_v 1._o a_o general_n return_v of_o all_o disease_n and_o disaster_n when_o the_o operation_n of_o opium_n be_v over_o because_o it_o do_v not_o as_o be_v show_v operate_v as_o a_o alterative_a but_o a_o please_a diverter_n of_o the_o sensitive_a soul_n for_o some_o time_n during_o which_o it_o cause_v a_o general_a relaxation_n of_o all_o the_o sensile_a part_n whereby_o the_o animal_n spirit_n be_v expanded_a grow_v unfit_a to_o convey_v impression_n smart_o which_o be_v requisite_a to_o cause_v a_o sense_n of_o pain_n etc._n etc._n as_o have_v be_v often_o say_v but_o it_o cure_v several_a distemper_n viz._n such_o as_o please_v and_o comfort_v the_o sensitive_a soul_n compose_v the_o spirit_n relaxation_n perspiration_n sweat_v etc._n etc._n can_v quite_o take_v away_o of_o which_o more_o particular_o when_o we_o come_v to_o speak_v of_o the_o use_n of_o opium_n in_o cure_n 2._o sweat_n happen_v in_o the_o declination_n of_o its_o operation_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v because_o that_o now_o all_o the_o parâ—s_a contract_n which_o by_o their_o relaxation_n suspend_v all_o humour_n during_o its_o operation_n do_v mechanical_o squeeze_v out_o the_o congest_a humour_n there_o be_v less_o room_n in_o the_o body_n as_o be_v say_v of_o sweat_n upon_o awake_v by_o the_o return_n of_o the_o vigilative_a contraction_n after_o relaxation_n during_o the_o sleep_n which_o be_v to_o be_v compare_v to_o the_o relaxation_n during_o the_o operation_n of_o opium_n and_o the_o return_v of_o the_o contraction_n when_o it_o be_v end_v beside_o that_o both_o upon_o the_o go_v off_o of_o the_o operation_n and_o awake_v the_o motion_n of_o the_o heart_n grow_v more_o vigorous_a as_o it_o do_v upon_o motion_n by_o the_o intentive_a contraction_n do_v more_o powerful_o propell_v the_o humour_n out_o at_o the_o pore_n as_o happen_v in_o sweat_n upon_o motion_n 3._o frequent_v make_v of_o water_n happen_v partly_o by_o the_o titillation_n of_o the_o volatile_a salt_n as_o by_o cantharides_n etc._n etc._n that_o be_v now_o separate_v from_o the_o blood_n partly_o by_o the_o contraction_n of_o the_o whole_a body_n squeese_v it_o out_o at_o the_o kidney_n as_o when_o people_n be_v cold_a they_o make_v more_o water_n for_o that_o reason_n 4._o a_o looseness_n may_v and_o do_v happen_v sometime_o from_o the_o like_a contraction_n squeese_v out_o the_o humour_n that_o be_v suspend_v during_o the_o relaxation_n by_o the_o opium_n which_o be_v common_a for_o such_o contraction_n to_o cause_n as_o by_o cold_a terror_n etc._n etc._n and_o because_o sensation_n grow_v more_o nice_a and_o irritable_a by_o the_o humour_n by_o reason_n of_o the_o contraction_n which_o be_v the_o more_o for_o the_o grievance_n of_o fail_v of_o the_o pleasure_n of_o opium_n therefore_o 5._o disease_n pain_n etc._n etc._n seem_v worse_o upon_o the_o return_n of_o the_o grievance_n because_o of_o the_o great_a ease_n they_o have_v during_o the_o operation_n of_o the_o opium_n contraria_fw-la inter_fw-la se_fw-la magis_fw-la elucescunt_fw-la and_o it_o be_v particular_o observe_v of_o pleasure_n that_o it_o leave_v man_n worse_o than_o it_o find_v they_o thus_o a_o man_n be_v worse_a more_o sad_a etc._n etc._n post_fw-la coitum_fw-la more_o melancholy_a after_o all_o sort_n of_o pleasure_n insomuch_o that_o it_o be_v grow_v to_o a_o proverb_n viz._n after_o merry_a come_v sorry_a or_o after_o mirth_n come_v sorrow_n as_o also_o minus_n gaudebis_fw-la minus_fw-la dolebis_fw-la therefore_o 6._o melaneholy_n do_v often_o if_o not_o always_o happen_v in_o some_o degree_n after_o its_o operation_n be_v end_v 1._o because_o of_o the_o return_n of_o the_o contraction_n or_o toil_n of_o the_o sensitive_a soul_n 2._o because_o as_o be_v say_v the_o sense_n of_o pleasure_n new_o lose_v aggravate_v the_o sorrow_n as_o have_v be_v show_v after_o coition_n etc._n etc._n 7._o the_o pulse_n be_v narrow_a because_o the_o contraction_n return_v with_o melancholy_a and_o return_v of_o disaster_n improve_v when_o that_o so_o happen_v as_o it_o general_o do_v 8._o itch_a of_o the_o skin_n happen_v about_o this_o time_n because_o that_o now_o the_o volatile_a salt_n which_o cause_v tuillation_n be_v arrive_v as_o far_o as_o the_o skin_n upon_o its_o march_n out_o of_o the_o body_n chap._n xxi_o the_o explication_n of_o the_o effect_n of_o opium_n in_o a_o excessive_a do_v the_o cause_n of_o most_o of_o these_o effect_n will_v be_v evident_a from_o the_o explication_n of_o the_o former_a because_o the_o difference_n be_v only_o in_o the_o quantity_n of_o the_o opium_n therefore_o i_o be_o often_o necessitate_v to_o speak_v much_o the_o same_o as_o i_o have_v do_v before_o you_o can_v expect_v any_o good_a effect_n from_o its_o excess_n any_o more_o than_o you_o have_v from_o wine_n though_o the_o best_a of_o cordial_n next_o to_o the_o sal._n volatile_a oleosum_fw-la of_o opium_n but_o rather_o less_o because_o opium_n be_v join_v to_o a_o pernicious_a rosin_n which_o you_o may_v be_v sure_o will_v be_v very_o grievous_a to_o the_o stomach_n in_o great_a quantity_n if_o it_o be_v so_o in_o little_a the_o evil_a effect_n in_o this_o case_n do_v main_o proceed_v either_o from_o too_o much_o relaxation_n as_o in_o drunkenness_n or_o from_o the_o rosin_n at_o stomach_n 1._o a_o heat_n at_o stomach_n be_v cause_v by_o the_o intense_a heat_n of_o the_o opium_n in_o a_o great_a quantity_n it_o be_v sensible_o a_o very_a hot_a thing_n 2._o the_o sense_n of_o weight_n at_o stomach_n be_v cause_v by_o the_o great_a relaxation_n that_o it_o cause_n which_o render_v the_o stomach_n proportionable_o weak_a and_o unable_a to_o endeavour_v its_o own_o relief_n so_o that_o the_o rosin_n etc._n etc._n lie_v heavy_a upon_o it_o thus_o we_o find_v a_o great_a heaviness_n at_o stomach_n when_o any_o thing_n grieve_v it_o that_o it_o can_v reject_v or_o discharge_v 3._o gaity_n of_o humour_n be_v cause_v at_o first_o as_o by_o the_o pleasure_n of_o a_o great_a quantity_n of_o wine_n by_o its_o please_a agreeableness_n to_o the_o membrane_n at_o stomach_n till_o the_o relaxation_n grow_v enormous_a as_o by_o a_o great_a do_v of_o wine_n sudden_o drink_v to_o which_o it_o be_v very_o like_a in_o all_o its_o effect_n except_o such_o as_o proceed_v from_o the_o rosin_n stick_v at_o stomach_n which_o wine_n have_v not_o 4._o sardonick_a laughter_n be_v cause_v as_o you_o see_v in_o drunken_a people_n when_o they_o be_v disable_v by_o the_o great_a relaxation_n that_o they_o can_v well_o express_v themselves_o by_o the_o fail_a tongue_n they_o endeavour_v it_o by_o a_o silly_a kind_n of_o feign_a or_o make_v laughter_n as_o they_o call_v it_o while_o the_o please_a titillation_n at_o stomach_n much_o incline_v they_o to_o mirth_n if_o they_o know_v how_o to_o manage_v and_o carry_v it_o on_o 5._o laxity_n and_o consequent_o debility_n of_o all_o part_n be_v cause_v by_o the_o extraordinary_a relaxation_n of_o they_o by_o a_o continual_a and_o permanent_a sense_n of_o pleasure_n which_o happen_v considerable_o in_o the_o momentary_a pleasure_n of_o venus_n much_o more_o in_o this_o continual_a and_o last_a pleasure_n when_o a_o great_a do_v make_v it_o intense_a as_o in_o drunkenness_n 6._o alienation_n of_o the_o mind_n be_v cause_v as_o in_o drunkenness_n by_o a_o over_o relaxation_n of_o the_o brain_n and_o its_o membrane_n 7._o loss_n of_o memory_n happen_v by_o the_o same_o mean_n as_o in_o drunkenness_n so_o 8._o darkness_n of_o eye_n be_v cause_v by_o a_o relaxation_n of_o the_o coat_n and_o membrane_n of_o the_o eye_n but_o main_o by_o the_o expansion_n of_o the_o animal_n spirit_n by_o that_o relaxation_n which_o as_o in_o sleep_n render_v they_o unfit_a to_o convey_v the_o impression_n of_o light_n etc._n etc._n 9_o laxity_n of_o the_o cornea_n be_v from_o the_o same_o relaxation_n 10._o appearance_n of_o various_a colour_n happen_v by_o as_o be_v say_v the_o unevenness_n of_o the_o cornea_n etc._n etc._n when_o so_o relax_v whereas_o when_o it_o be_v due_o
and_o frequent_a erection_n be_v and_o must_v be_v from_o the_o same_o cause_n 17._o nocturnal_a pollution_n be_v necessary_a consequence_n of_o the_o relaxation_n and_o the_o titillation_n cause_v by_o those_o volatile_a salt_n as_o be_v say_v chap._n xxiii_o the_o explication_n of_o the_o effect_n of_o leave_v off_o opium_n after_o a_o long_a and_o lavish_a use_v thereof_o i._o great_a and_o even_o intolerable_a distress_n anxiety_n and_o depression_n of_o spirit_n do_v happen_v 1._o because_o the_o sensitive_a soul_n who_o be_v so_o much_o comfort_v divert_v and_o support_v by_o the_o habitual_a and_o dear_o belove_a pleasure_n that_o opium_n cause_n be_v sudden_o deprive_v thereof_o by_o which_o it_o be_v main_o sustain_v be_v exceed_o disappoint_v and_o cast_v down_o 2._o because_o he_o now_o labour_v under_o the_o sore_a burden_n of_o the_o three_o contraction_n so_o that_o every_o thing_n seem_v and_o be_v real_o more_o grievous_a â—o_o he_o for_o now_o it_o act_v as_o one_o in_o pain_n or_o grief_n and_o every_o thing_n affect_v he_o more_o smart_o proportionable_a to_o the_o compression_n cause_v thereby_o of_o the_o animal_n spirit_n unless_o he_o return_v to_o the_o pleasure_n of_o opium_n which_o elevate_v it_o again_o or_o use_v generous_a wine_n as_o its_o substitute_n though_o it_o do_v not_o equal_v it_o either_o in_o the_o intenseness_n or_o duration_n of_o the_o pleasure_n unless_o repeat_v as_o i_o have_v some_o where_o direct_v once_o in_o half_a a_o hour_n or_o a_o hour_n in_o a_o moderate_a manner_n which_o cause_v a_o continuance_n of_o the_o pleasure_n though_o it_o can_v equal_v the_o intenseness_n of_o that_o of_o opium_n which_o therefore_o have_v the_o great_a effect_n ii_o a_o return_n of_o all_o disease_n pain_n and_o disaster_n must_v happen_v general_o because_o the_o opium_n take_v they_o off_o by_o a_o bare_a diversion_n of_o the_o sense_n thereof_o by_o pleasure_n iii_o dangerous_a looseness_n happen_v sometime_o because_o the_o sensation_n grow_v more_o grievous_a for_o as_o the_o pleasant_a sensation_n cause_v by_o opium_n take_v away_o the_o perception_n of_o the_o irritation_n of_o humour_n so_o the_o grievance_n of_o lose_v that_o pleasure_n cause_v contraction_n make_v all_o sensation_n smart_a and_o consequent_o more_o irritate_v so_o that_o the_o humour_n have_v thereby_o more_o of_o the_o effect_n of_o purger_n which_o operate_v as_o all_o agree_v by_o irritation_n beside_o that_o the_o humour_n before_o detain_v and_o suspend_v by_o relaxation_n as_o in_o sleep_n be_v now_o therefore_o pour_v down_o in_o great_a quantity_n by_o the_o advance_a contraction_n squeese_v they_o out_o as_o the_o return_n of_o the_o vigilative_a contraction_n after_o sleep_n cause_n man_n to_o be_v more_o apt_a to_o go_v to_o stool_n upon_o awake_v or_o get_v up_o in_o the_o morning_n which_o may_v be_v well_o compare_v in_o some_o measure_n to_o purge_v after_o leave_v off_o the_o use_n of_o opium_n since_o it_o relax_n as_o sleep_n do_v and_o that_o for_o a_o much_o long_a time_n by_o a_o continue_a use_n thereof_o iv_o death_n common_o follow_v for_o all_o the_o reason_n aforesaid_a especial_o the_o great_a and_o intolerable_a distress_n of_o soul_n that_o they_o be_v under_o unless_o opium_n be_v use_v which_o soon_o set_v they_o right_o or_o wine_n its_o substitute_n so_o frequent_o use_v as_o to_o continue_v its_o cordial_a pleasure_n at_o stomach_n nothing_o now_o remain_v but_o to_o take_v a_o short_a review_n to_o see_v whether_o i_o have_v explain_v all_o the_o amaze_a contradiction_n that_o seem_v to_o be_v in_o the_o effect_n of_o opium_n for_o though_o it_o be_v real_o do_v yet_o may_v it_o not_o so_o well_o appear_v as_o when_o set_v one_o against_o the_o other_o it_o will_v be_v tautology_n to_o repeat_v all_o the_o reason_n therefore_o i_o shall_v only_o mention_v they_o in_o the_o close_a order_n i_o at_o first_o enumerate_v they_o that_o you_o may_v see_v that_o they_o be_v all_o explicate_v in_o the_o former_a discourse_n you_o may_v well_o remember_v that_o i_o have_v show_v 1._o how_o it_o cause_v sleep_v and_o watch_v in_o divers_a person_n 2._o how_o it_o cause_v and_o prevent_v sweat_n 3._o how_o it_o relax_n and_o stop_n looseness_n even_o by_o relax_v 4._o how_o it_o stop_v flux_n and_o promote_v sweat_v and_o perspiration_n 5._o how_o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v it_o 6._o how_o it_o cause_v stupidity_n if_o you_o sit_v or_o lie_v still_o otherwise_o promptitude_n in_o business_n 7._o how_o it_o cause_v cloudiness_n and_o serenity_n that_o if_o one_o lie_v still_o and_o doze_n this_o if_o he_o keep_v in_o action_n that_o by_o a_o excessive_a and_o lavish_a use_v thereof_o which_o cause_v moapishness_n this_o by_o a_o temperate_a occasional_a take_v thereof_o especial_o in_o the_o morning_n upon_o journey_n etc._n etc._n 8._o how_o it_o excite_v the_o spirit_n yet_o quiet_v and_o compose_v they_o in_o hysterick_n fit_v diary_n fever_n from_o pain_n commotion_n etc._n etc._n 9_o how_o that_o it_o be_v very_o hot_a and_o take_v of_o fever_n 10._o how_o though_o it_o be_v hot_a and_o bitter_a yet_o it_o lessen_v appetite_n and_o hunger_n which_o be_v a_o grievous_a sensation_n by_o cause_v a_o pleasant_a one_o 11._o how_o it_o sometime_o stop_v urine_n by_o relax_v the_o bladder_n suspending_a humour_n etc._n etc._n and_o promote_v it_o by_o its_o tickle_a volatile_a salt_n as_o cantharides_n bee_n aunt_n etc._n etc._n do_v 12._o how_o it_o relax_n and_o thereby_o weaken_v as_o in_o sleep_n etc._n etc._n yet_o enable_v to_o perform_v labour_n journey_n etc._n etc._n with_o great_a euphory_n by_o divertive_a pleasure_n 13._o how_o it_o cause_v and_o prevent_v abortion_n that_o by_o over-relaxing_a this_o by_o allay_a pain_n terror_n etc._n etc._n that_o may_v cause_v it_o 14._o how_o it_o stop_v vomit_v by_o take_v off_o irritation_n etc._n etc._n and_o cause_v it_o by_o the_o adherence_n of_o its_o indigestible_a and_o viscid_a rosin_n 15._o how_o it_o stop_v purge_v and_o sometime_o cause_v it_o by_o the_o dissolution_n of_o its_o rosin_n by_o a_o strong_a digestion_n fix_a salt_n etc._n etc._n when_o its_o quantity_n be_v considerable_a which_o make_v it_o happen_v but_o rare_o 16._o how_o though_o acrimonious_a it_o take_v away_o the_o sense_n of_o acrimony_n 17._o how_o it_o cause_v madness_n and_o cure_v it_o by_o compose_v the_o spirit_n etc._n etc._n 18._o how_o it_o cause_v palsy_n by_o relax_v the_o part_n and_o make_v they_o susceptible_a of_o humour_n cause_v ill_a digestion_n etc._n etc._n and_o may_v cure_v they_o as_o dr._n willis_n give_v a_o instance_n by_o open_v the_o pore_n 19_o how_o it_o cause_v palsy_n and_o cure_n stupor_n etc._n etc._n that_o proceed_v from_o cold_a and_o contract_n cause_n 20._o how_o it_o cause_v dryness_n in_o the_o mouth_n yet_o by_o take_v off_o fever_n often_o cure_v it_o 21._o how_o it_o take_v off_o hiccough_n and_o cause_v they_o as_o it_o do_v vomit_v and_o for_o the_o same_o cause_n 22._o how_o it_o stanch_v blood_n by_o quiet_v its_o motion_n yet_o promote_v the_o menses_fw-la and_o lochia_n by_o relax_v open_v and_o widen_v the_o vessel_n and_o pore_n 23._o how_o it_o stop_v critical_a motion_n that_o depend_v upon_o irritation_n and_o contraction_n and_o promote_v such_o as_o depend_v upon_o open_v the_o pore_n 24._o how_o it_o revive_v people_n that_o be_v at_o the_o point_n of_o death_n for_o want_n of_o opium_n or_o by_o violent_a contraction_n and_o convulsion_n and_o be_v fatal_a to_o other_o weak_a person_n 25._o how_o it_o cause_v convulsion_n by_o its_o grieve_v rosin_n and_o cure_v they_o by_o quiet_v and_o compose_v the_o spirit_n by_o please_v they_o 26._o how_o it_o cause_v contraction_n by_o the_o grievous_a sensation_n that_o its_o rosin_n cause_n and_o relaxation_n by_o the_o pleasant_a sensation_n that_o its_o salvolatile_a oleosum_fw-la cause_n by_o that_o it_o cause_v many_o ill_a effect_n not_o here_o name_v and_o by_o this_o it_o cure_v they_o for_o how_o can_v such_o contrary_a cause_n according_a as_o one_o or_o the_o other_o prevail_v not_o cause_v contrary_a and_o seem_o contradictory_n effect_n at_o divers_a time_n and_o in_o divers_a person_n 27._o how_o it_o relax_n yet_o cause_v the_o tension_n rigidity_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n by_o its_o titillation_n thus_o have_v you_o all_o even_o the_o most_o mysterious_a and_o seem_o contradictory_n effect_n of_o opium_n explain_v and_o reconcile_v and_o that_o so_o easy_o that_o if_o there_o be_v no_o other_o proof_n of_o the_o truth_n of_o my_o foundation_n it_o be_v sufficient_a to_o convince_v any_o man_n of_o its_o validity_n consider_v the_o vastness_n of_o the_o number_n and_o perplexity_n of_o the_o nature_n of_o those_o effect_n that_o be_v all_o with_o such_o facility_n explain_v be_v able_a even_o
to_o disparage_v the_o performance_n as_o mean_v and_o obvious_a like_o that_o of_o the_o circulation_n of_o the_o blood_n or_o america_n when_o find_v out_o do_v not_o the_o newness_n of_o the_o thing_n the_o baffle_a endeavour_n of_o all_o mankind_n and_o the_o seem_a impossibility_n of_o ever_o find_v it_o out_o which_o be_v almost_o agree_v upon_o speak_v in_o its_o behalf_n consider_v that_o nothing_o can_v be_v plain_a and_o easy_a but_o what_o be_v true_a and_o consequent_o nothing_o valuable_a but_o what_o be_v so_o what_o be_v true_a knowledge_n but_o the_o knowledge_n of_o thing_n as_o they_o real_o be_v and_o when_o a_o thing_n be_v know_v as_o real_o as_o it_o be_v it_o must_v be_v plain_a and_o never_o so_o till_o then_o for_o to_o take_v a_o thing_n to_o be_v what_o it_o be_v not_o be_v all_o darkness_n error_n puzzle_n confusion_n and_o vanity_n as_o all_o discourse_n of_o opium_n have_v hitherto_o be_v it_o be_v no_o wonder_n then_o that_o the_o cause_n of_o the_o operation_n of_o opium_n grow_v more_o and_o more_o obscure_a while_o they_o state_v the_o cold_a quality_n of_o very_a hot_a opium_n the_o belch_a up_o of_o vulcano_n of_o fume_n from_o the_o stomach_n to_o the_o head_n which_o have_v no_o existence_n their_o act_n as_o a_o poison_n of_o the_o animal_n spirit_n their_o fix_v and_o coagulate_v they_o their_o clog_a they_o by_o adherence_n or_o cloud_v they_o their_o wedge_a themselves_o among_o the_o animal_n spirit_n none_o know_v how_o and_o thereby_o disable_n they_o their_o stuff_v the_o pore_n of_o the_o brain_n or_o compress_v it_o and_o thereby_o hinder_v the_o generation_n of_o animal_n spirit_n to_o be_v the_o cause_n of_o the_o noble_a and_o pleasant_a operation_n of_o opium_n without_o any_o foundation_n in_o nature_n or_o the_o least_o evidence_n of_o sense_n or_o reason_n but_o vain_a fantastical_a imagination_n form_v in_o the_o chimera-forges_a of_o their_o wanton_a brain_n while_o they_o endeavour_v right_o or_o wrong_n to_o appear_v considerable_a folk_n by_o do_v nothing_o to_o the_o purpose_n in_o a_o kind_n of_o pretty_a plausible_a and_o impose_v manner_n thereby_o stuff_v the_o unwary_a world_n with_o wrong_n and_o vain_a conception_n and_o impertinent_a prejudices_fw-la which_o be_v the_o great_a obstacle_n of_o knowledge_n i_o will_v fain_o know_v which_o of_o those_o hypothesise_n can_v tolerable_o solve_v 1_o in_o 10_o of_o the_o phenomena_n that_o i_o have_v enumerate_v or_o indeed_o any_o one_o phenomenon_n true_o mechanical_o and_o demonstrative_o yet_o be_v those_o whim_n the_o glorious_a production_n of_o thousand_o of_o year_n study_n and_o solicitous_a disquisition_n though_o every_o one_o that_o take_v opium_n actual_o feel_v the_o true_a cause_n of_o its_o operation_n viz._n the_o please_a delight_n that_o it_o occasion_v by_o affect_v the_o membrane_n and_o animal_n spirit_n after_o the_o manner_n that_o i_o have_v at_o large_a set_v forth_o good_a god_n what_o blund'r_a groper_n be_v mankind_n who_o daily_o feel_v the_o cause_n it_o never_o can_v find_v though_o thousand_o seek_v it_o with_o a_o eager_a mind_n chap._n xxiv_o of_o opium_n separate_v from_o its_o noxious_a part_n or_o rosin_n and_o whether_o it_o be_v a_o panacea_fw-la etc._n etc._n thus_o far_o have_v i_o speak_v of_o crude_a opium_n joint_o with_o its_o rosin_n or_o noxious_a part_n now_o i_o will_v consider_v it_o separate_v from_o it_o and_o show_v how_o to_o do_v it_o galen_n say_v that_o it_o be_v very_o difficult_a to_o find_v a_o excellent_a remedy_n without_o a_o noxious_a quality_n and_o it_o be_v as_o difficult_a to_o find_v any_o thing_n so_o noxious_a as_o not_o to_o afford_v a_o good_a medicament_n which_o you_o see_v in_o viper_n scorpion_n mercury_n etc._n etc._n all_o or_o most_o physician_n unanimous_o agree_v that_o opium_n have_v such_o a_o noxious_a quality_n that_o cause_v vomit_n hiccough_n distress_n anxiety_n convulsion_n chief_o at_o or_o about_o the_o region_n of_o the_o stomach_n and_o that_o if_o it_o be_v free_v from_o it_o it_o will_v be_v the_o noble_a of_o medicament_n who_o can_v otherwise_o imagine_v see_v it_o be_v so_o excellent_a and_o universal_a a_o remedy_n as_o it_o be_v now_o use_v in_o the_o world_n without_o such_o a_o excellent_a preparation_n thereof_o wherein_o the_o noxious_a principle_n be_v separate_v from_o it_o of_o which_o paracelsus_n say_v that_o whoever_o shall_v enjoy_v it_o will_v be_v a_o professor_n of_o no_o less_o knowledge_n than_o apollo_n machaon_n or_o podalyrius_n though_o he_o be_v the_o great_a master_n of_o arcanas_fw-la panaceas_fw-la etc._n etc._n yet_o do_v he_o confess_v that_o a_o preparation_n of_o opium_n stand_v he_o in_o stead_n and_o perform_v his_o business_n when_o all_o his_o great_a medicament_n fail_v he_o and_o that_o it_o will_v dissolve_v disease_n as_o fire_n doeâ—_n snow_n or_o use_v word_n to_o the_o same_o effect_n helmont_n be_v in_o a_o kind_n of_o rapture_n upon_o consideration_n of_o its_o excellency_n burst_v out_o into_o this_o exclamation_n happy_a be_v the_o sick_a man_n who_o physician_n know_v how_o to_o separate_v the_o deadly_a or_o noxious_a part_v from_o opium_n platerus_n affirm_v that_o he_o can_v with_o a_o preparation_n of_o opium_n preserve_v the_o break_a wheel_n of_o life_n etmuller_n say_v that_o opium_n may_v 〈◊〉_d be_v esteem_v a_o general_a remedy_n and_o the_o main_a end_n of_o his_o tract_n de_fw-fr paruis_fw-la morborum_fw-la initiis_fw-la be_v to_o show_v how_o volatiles_fw-la more_o especial_o salia-volatilia-oleosa_a as_o that_o of_o opium_n may_v in_o small_a quantity_n alter_v we_o and_o cure_v our_o disease_n it_o be_v endless_a to_o tell_v you_o the_o eulogy_n of_o the_o learned_a concern_v such_o a_o preparation_n of_o opium_n which_o they_o general_a conclude_v to_o be_v a_o most_o noble_a panacea_fw-la therefore_o many_o and_o very_o solicitous_a have_v be_v the_o disquisition_n of_o the_o ingenious_a and_o industrious_a to_o find_v out_o this_o heroic_a generous_a and_o most_o glorious_a medicament_n i_o be_o full_o satisfy_v that_o the_o pure_a sal-volatile-oleosum_a of_o opium_n due_o separate_v from_o its_o noxious_a rosin_n dross_n etc._n etc._n be_v the_o very_a thing_n some_o of_o the_o reason_n that_o convince_v i_o be_v as_o follow_v viz._n 1._o because_o opium_n have_v no_o other_o principle_n in_o it_o that_o signify_v any_o thing_n as_o to_o its_o laudable_a and_o noble_a effect_n but_o its_o sal_fw-la volatile_a oleosum_fw-la as_o have_v be_v show_v 2._o because_o the_o sal_fw-la volatile-oleosum_a of_o opium_n produce_v all_o its_o good_a effect_n 3._o because_o the_o sal-volatile-oleosum_a due_o separate_v from_o its_o rosin_n and_o other_o principle_n produce_v no_o ill_a effect_n in_o a_o moderate_a do_v this_o add_v to_o what_o have_v be_v discourse_v at_o large_a of_o the_o principle_n of_o opium_n be_v i_o think_v sufficient_a to_o satisfy_v any_o man_n that_o the_o sal-volatile-oleosum_a of_o opium_n so_o separate_v be_v the_o great_a panacea_fw-la that_o be_v seek_v for_o however_o because_o we_o be_v upon_o the_o great_a thing_n in_o physic_n as_o may_v be_v well_o infer_v from_o what_o have_v be_v already_o say_v and_o that_o the_o world_n have_v be_v under_o great_a fear_n jealousy_n and_o blindness_n concern_v this_o matter_n and_o the_o use_v of_o opium_n it_o will_v be_v well_o worth_a our_o while_n to_o give_v all_o imaginable_a satisfaction_n in_o this_o case_n therefore_o i_o will_v first_o lay_v down_o all_o the_o requisite_a qualification_n of_o a_o complete_a panacea_fw-la as_o far_o as_o i_o can_v collect_v out_o of_o the_o most_o eminent_a author_n and_o my_o own_o consideration_n thereof_o second_o i_o will_v particular_o inquire_v as_o to_o each_o of_o the_o qualification_n whether_o the_o sal_fw-la volatile-oleosum_a of_o opium_n due_o separate_v from_o every_o other_o principle_n of_o opium_n be_v furnish_v therewith_o three_o i_o will_v show_v you_o how_o due_o to_o separate_v its_o dross_n rosin_n etc._n etc._n so_o as_o to_o leave_v a_o pure_a sincere_a sal-volatile-oleosum_a of_o opium_n for_o use._n the_o requisite_a qualification_n of_o a_o panacea_fw-la be_v these_o viz._n 1._o that_o it_o shall_v high_o please_v our_o sensation_n at_o stomach_n because_o the_o stomach_n be_v contrive_v and_o appoint_v by_o god_n and_o nature_n as_o the_o touchstone_n to_o try_v a_o sentinel_n true_o to_o inform_v and_o a_o critical_a judge_n to_o determine_v what_o be_v or_o be_v not_o agreeable_a to_o our_o nature_n in_o general_a and_o therefore_o as_o have_v be_v show_v endue_v with_o a_o wonderful_a sagacity_n and_o nicety_n of_o sensation_n for_o that_o end_n it_o follow_v then_o that_o a_o panacea_fw-la shall_v be_v very_o please_v and_o agreeable_a to_o the_o stomach_n and_o therefore_o very_o cordial_a 2._o that_o it_o shall_v be_v high_o please_v to_o the_o sensitive_a soul_n which_o be_v the_o principle_n of_o all_o motion_n action_n
darkness_n of_o the_o eye_n see_v thing_n double_a various_a colour_n before_o the_o eye_n loss_n of_o feel_v ease_n from_o pain_n etc._n etc._n deadness_n of_o the_o eye_n to_o the_o view_n dilatation_n of_o the_o pupilla_fw-la efflorescence_n of_o the_o skin_n laxity_n of_o the_o low_a jaw_n intumescence_n and_o laxity_n of_o the_o lip_n falter_v of_o the_o tongue_n sardonick_a laughter_n laxity_n and_o weakness_n of_o all_o part_n a_o general_a ineptitude_n to_o motion_n failure_n in_o make_v water_n go_v to_o stool_n and_o in_o all_o thing_n that_o require_v strength_n contraction_n motion_n etc._n etc._n difficulty_n of_o breathe_v a_o wide_a and_o slow_a pulse_n a_o condition_n in_o general_a very_a like_o that_o of_o drunkenness_n which_o also_o proceed_v from_o relaxation_n second_o when_o you_o be_v satisfy_v that_o relaxation_n be_v the_o cause_n use_v all_o mean_n to_o procure_v a_o due_a contraction_n of_o all_o part_n which_o be_v to_o be_v do_v 1._o by_o remove_v the_o cause_n of_o the_o relaxation_n 2._o by_o use_v all_o good_a mean_n for_o contraction_n first_o therefore_o give_v a_o brisk_a quick_a and_o strong_a vomit_n both_o to_o discharge_v the_o opiate_n and_o cause_n contraction_n of_o part_n by_o a_o grievous_a sensation_n proportion_n it_o to_o the_o deadness_n stupidity_n or_o sleepiness_n of_o the_o person_n so_o as_o to_o give_v it_o of_o twice_o the_o ordinary_a strength_n of_o vomit_n in_o case_n there_o be_v great_a danger_n from_o those_o symptom_n and_o that_o they_o be_v of_o a_o high_a nature_n after_o the_o person_n have_v vomit_v 3_o or_o 4_o time_n or_o so_o often_o as_o that_o you_o may_v judge_v the_o stomach_n well_o clear_v of_o the_o opiate_n give_v half_o a_o ounce_n of_o cream_n of_o tartar_n fine_o powder_v in_o thin_a broth_n whey_n water_n small_a beer_n or_o any_o convenient_a liquid_a which_o will_v correct_v the_o opiate_n if_o any_o remain_v at_o stomach_n turn_v the_o vomit_n to_o a_o purger_n to_o clear_v the_o intestine_n also_o and_o contribute_v much_o to_o the_o contraction_n of_o part_n which_o you_o must_v always_o have_v in_o your_o thought_n as_o the_o roll_a intention_n in_o this_o case_n therefore_o second_o you_o must_v use_v contracter_n all_o the_o time_n the_o chief_a of_o which_o be_v cold_a grievous_a sensation_n or_o pain_n terror_n fear_v voluntary_a motion_n and_o acid_n which_o last_n can_v be_v so_o well_o use_v during_o the_o vomit_v lest_o they_o stop_v it_o therefore_o especial_o if_o the_o person_n be_v very_o stupid_a keep_v he_o very_o cold_a for_o he_o will_v hardly_o feel_v it_o nor_o take_v cold_a because_o the_o relaxation_n and_o the_o insensibleness_n of_o grievance_n by_o cold_a etc._n etc._n keep_v the_o pore_n open_a let_v he_o be_v if_o possible_a in_o some_o motion_n as_o walk_v hew_v saw_v knock_v tug_v etc._n etc._n the_o more_o violent_a it_o be_v the_o better_a because_o it_o cause_v more_o contraction_n and_o agitation_n to_o prevent_v sopor_n to_o force_v he_o to_o motion_n if_o need_v be_v prick_a pinch_a or_o whip_v he_o about_o the_o leg_n etc._n etc._n will_v be_v of_o good_a use_n because_o grievous_a sensation_n add_v defensive_a contraction_n which_o be_v the_o great_a sort_n to_o that_o of_o the_o intentive_a contraction_n by_o voluntary_a motion_n these_o mean_n fail_v he_o shall_v be_v expose_v stark_o naked_a to_o the_o cold_a air_n and_o in_o desperate_a case_n throw_v sudden_o at_o unaware_o into_o cold_a water_n by_o which_o mean_v you_o cause_n terror_n surprise_v and_o cold_a which_o be_v the_o high_a and_o most_o forcible_a contracter_n to_o conspire_v to_o the_o contraction_n of_o part_n hence_o it_o be_v that_o drunken_a people_n who_o be_v so_o from_o relaxation_n become_v sober_a as_o in_o a_o moment_n by_o that_o mean_n all_o the_o time_n but_o during_o the_o vomit_v let_v he_o use_v cold_a acid_n in_o great_a plenty_n and_o very_o manifest_o acid_a for_o they_o will_v not_o only_o contribute_v to_o contraction_n but_o very_o much_o correct_v the_o opiate_n to_o this_o end_n juice_n of_o orange_n or_o lemon_n verjuice_n or_o water_n acidulate_v to_o a_o good_a degree_n by_o verjuice_n vinegar_n juice_n of_o lemon_n spirit_n of_o vitriol_n sulphur_n or_o the_o like_a will_v be_v very_o proper_a where_o you_o have_v not_o the_o convenience_n to_o plunge_v they_o into_o cold_a water_n as_o be_v direct_v dash_v or_o pump_v very_o cold_a water_n or_o water_n with_o a_o four_o part_n of_o vinegar_n upon_o their_o naked_a body_n will_v be_v of_o great_a use_n especial_o if_o surprise_o do_v to_o cause_v the_o more_o terror_n and_o concern_v these_o thing_n may_v be_v do_v more_o or_o lâ—ss_o as_o cause_n may_v require_v which_o must_v be_v leave_v to_o the_o discretion_n of_o the_o present_a physician_n or_o friend_n and_o standard_n by_o in_o case_n there_o be_v no_o physician_n i_o only_o caution_n that_o contracter_n shall_v not_o be_v use_v too_o spare_o and_o that_o you_o shall_v never_o cease_v to_o advance_v in_o the_o use_n of_o they_o till_o you_o perceive_v their_o good_a effect_n and_o then_o to_o continue_v they_o as_o occasion_n require_v note_v that_o the_o case_n may_v well_o happen_v that_o the_o rosin_n may_v stick_v at_o stomach_n and_o yet_o no_o sign_n or_o symptom_n appear_v but_o those_o of_o relaxation_n by_o reason_n that_o the_o feel_n at_o stomach_n may_v thereby_o be_v disable_v to_o take_v any_o notice_n of_o it_o to_o be_v sure_a of_o this_o you_o have_v no_o other_o mean_n because_o the_o symptom_n and_o effect_n of_o grievous_a sensation_n can_v appear_v where_o it_o be_v not_o for_o the_o aforesaid_a reason_n but_o to_o examine_v whether_o the_o opiate_n be_v a_o resinous_a one_o as_o crude_a opium_n extract_v out_o of_o spirit_n of_o wine_n or_o the_o like_a for_o than_o you_o may_v conclude_v especial_o if_o they_o be_v give_v in_o a_o massy_a solid_a form_n as_o that_o of_o pill_n etc._n etc._n without_o sever_n the_o particle_n of_o the_o rosin_n by_o other_o thing_n as_o the_o yolk_n of_o a_o egg_n etc._n etc._n that_o the_o rosin_n may_v in_o all_o probability_n stick_v at_o stomach_n though_o its_o symptom_n do_v not_o appear_v for_o the_o aforesaid_a reason_n in_o such_o a_o case_n the_o best_a advice_n that_o i_o can_v give_v be_v external_o to_o use_v all_o contract_n mean_v as_o be_v direct_v and_o internal_o the_o mean_v prescribe_v for_o dissolution_n of_o the_o rosin_n for_o you_o will_v thereby_o answer_v both_o intention_n failure_n of_o make_v water_n often_o happen_v in_o these_o case_n which_o you_o may_v general_o help_v by_o only_o clap_v the_o scrotum_fw-la to_o the_o cold_a chamber_n pot_n or_o into_o cold_a water_n and_o if_o that_o will_v not_o do_v put_v some_o vinegar_n into_o the_o water_n and_o that_o fail_v he_o must_v be_v strip_v and_o cold_a water_n pump_v or_o dash_v upon_o the_o region_n of_o the_o bladder_n iii_o to_o cure_v the_o ill_a effect_n of_o a_o long_a and_o lavish_a use_n of_o opium_n these_o effect_n as_o you_o may_v easy_o observe_v if_o you_o take_v a_o view_n of_o they_o where_o they_o be_v enumerate_v in_o chap._n 6._o be_v either_o 1._o from_o a_o overmuch_o and_o habitual_a relaxation_n of_o part_n as_o weakness_n a_o moapish_a disposition_n diminution_n of_o appetite_n weakness_n of_o digestion_n dropsy_n weakness_n of_o memory_n etc._n etc._n or_o 2._o from_o acrimony_n as_o frequent_a irritation_n to_o make_v water_n priapism_n erection_n of_o the_o penis_n fruitless_a inclination_n to_o venery_n etc._n etc._n in_o this_o case_n as_o in_o that_o of_o old_a drunkard_n which_o be_v much_o the_o same_o there_o be_v no_o good_a to_o be_v do_v till_o the_o habitual_a cause_n be_v remove_v viz._n the_o take_v of_o opium_n which_o sudden_o to_o leave_v off_o be_v as_o be_v show_v very_o dangerous_a therefore_o in_o order_n to_o leave_v it_o off_o safe_o 1._o you_o must_v stop_v your_o hand_n and_o not_o increase_v the_o do_v that_o be_v take_v by_o which_o mean_v it_o will_v come_v gradual_o to_o have_v little_a or_o no_o effect_n 2._o when_o you_o find_v that_o it_o be_v come_v to_o that_o pass_n your_o work_n be_v half_o do_v then_o only_o lessen_v it_o 100th_o part_n every_o day_n till_o you_o come_v to_o take_v none_o at_o all_o 3._o if_o during_o this_o retrograde_a course_n you_o find_v any_o faintness_n drink_v a_o glass_n of_o good_a stomach-wine_n toties_fw-la quoties_fw-la as_o gentian_n or_o centary_a wine_n or_o the_o like_a make_v by_o infusion_n in_o claret_n or_o if_o you_o want_v such_o a_o glass_n of_o the_o claret_n itself_o which_o thing_n will_v excite_v the_o spirit_n and_o help_v digestion_n 4._o when_o you_o have_v quite_o end_v the_o take_v of_o opium_n continue_v to_o use_v such_o wine_n when_o you_o be_v faint_a and_o every_o morning_n take_v in_o a_o glass_n of_o
gentian_a wine_n two_o dram_fw-la of_o the_o chalybeate_a wine_n describe_v in_o the_o london_n dispensatory_a increase_v about_o a_o scruple_n every_o day_n till_o you_o come_v to_o half_a a_o ounce_n which_o take_v for_o two_o month_n at_o least_o afterward_o decrease_v as_o you_o increase_v till_o you_o come_v to_o one_o drachm_n and_o so_o give_v over_o but_o if_o you_o find_v oâ—osion_n you_o may_v continue_v that_o course_n long_o or_o as_o long_o as_o your_o physician_n think_v fit_a after_o all_o you_o may_v use_v a_o glass_n of_o claret_n when_o faint_a but_o be_v sure_a to_o be_v moderate_a and_o not_o run_v from_o one_o excess_n to_o another_o as_o for_o the_o acrimony_n of_o blood_n that_o be_v more_o during_o the_o take_v of_o opium_n and_o will_v soon_o after_o gradual_o wear_v off_o especial_o by_o the_o course_n direct_v if_o not_o camphire_n be_v the_o adequate_a remedy_n of_o which_o with_o equal_a part_n of_o white_a rosin_n and_o q._n s._n of_o mucilage_n of_o gum._n tragac._n you_o may_v make_v pill_n of_o â—_o grain_n weight_n take_v 4_o of_o they_o every_o night_n at_o bedtime_n in_o a_o rear_n yolk_n of_o a_o egg_n as_o long_o as_o it_o be_v necessary_a for_o camphire_n by_o its_o fine_a sulphur_n correct_v the_o volatile_a acrimony_n of_o cantharides_n opium_n etc._n etc._n and_o so_o allay_v titillation_n to_o venery_n etc._n etc._n as_o be_v observe_v iv_o the_o ill_a effect_n of_o a_o sudden_a leave_v off_o of_o opium_n as_o anxiety_n distress_n depression_n of_o spirit_n which_o as_o be_v say_v be_v very_o dangerous_a be_v remedy_v no_o other_o way_n but_o either_o 1._o by_o return_v to_o the_o use_v of_o opium_n which_o be_v a_o most_o certain_a cure_n and_o afterward_o if_o you_o please_v give_v over_o the_o use_n of_o it_o after_o the_o manner_n that_o i_o direct_v which_o you_o will_v find_v to_o be_v safe_a nor_o can_v i_o advise_v you_o to_o trust_v any_o other_o method_n of_o leave_v it_o off_o unless_o it_o be_v 2._o by_o substitute_v wine_n instead_o of_o opium_n which_o be_v not_o quite_o so_o safe_a or_o certain_a your_o best_a method_n of_o use_v it_o be_v to_o drink_v a_o good_a glass_n of_o it_o so_o often_o as_o to_o keep_v the_o comfort_n thereof_o at_o stomach_n continual_o that_o so_o it_o may_v answer_v the_o more_o permanent_a effect_n of_o opium_n and_o keep_v you_o from_o a_o faint_a condition_n but_o see_v also_o that_o this_o course_n be_v not_o convenient_a to_o be_v continue_v long_o you_o must_v gradual_o lessen_v the_o do_v of_o this_o as_o you_o be_v direct_v to_o do_v that_o of_o opium_n till_o you_o come_v to_o take_v none_o or_o at_o least_o a_o moderate_a and_o wholesome_a quantity_n note_v that_o if_o such_o as_o use_v to_o take_v opium_n be_v even_o almost_o expire_a for_o want_n of_o it_o you_o must_v to_o prevent_v imminent_a death_n give_v a_o liquid_a preparation_n thereof_o to_o the_o value_n of_o what_o the_o person_n be_v use_v to_o take_v in_o a_o cordial_a vehicle_n as_o spirit_n of_o wine_n brandy_n or_o the_o like_a because_o such_o hot_a spirituous_a vehicles_n do_v as_o have_v be_v show_v immediate_o give_v some_o comfort_n by_o actuate_a and_o warm_v our_o spirit_n till_o the_o opium_n come_v to_o operate_v which_o will_v not_o be_v long_o because_o it_o be_v in_o a_o liquid_a form_n if_o you_o find_v the_o person_n sink_v notwithstanding_o he_o may_v be_v keep_v up_o by_o repeat_v the_o brandy_n or_o cordial_n without_o any_o opium_n in_o it_o till_o the_o opiate_n operate_v which_o will_v certain_o by_o god_n help_n set_v he_o right_n in_o case_n it_o do_v but_o begin_v to_o operate_v before_o he_o be_v dead_a see_v the_o philos._n transact_v for_o june_n july_n august_n 1696._o note_v that_o it_o be_v a_o very_a false_a imagination_n that_o author_n have_v of_o the_o turk_n capacity_n by_o nature_n climate_n or_o the_o like_a to_o take_v more_o opium_n or_o in_o great_a quantity_n than_o we_o may_v but_o that_o they_o make_v more_o use_n of_o it_o and_o by_o that_o mean_n come_v to_o take_v 2_o or_o 3_o dram_fw-la a_o day_n for_o they_o begin_v with_o such_o small_a quantity_n as_o we_o common_o give_v till_o by_o a_o long_a custom_n of_o take_v it_o they_o come_v to_o take_v the_o say_a quantity_n which_o be_v but_o small_a in_o comparison_n of_o what_o several_a english_a people_n that_o have_v be_v use_v to_o it_o do_v or_o have_v take_v as_o i_o can_v name_v several_a to_o you_o if_o i_o have_v not_o reason_n to_o the_o contrary_a however_o i_o be_o at_o liberty_n to_o tell_v you_o the_o quantity_n though_o i_o must_v forbear_v name_v the_o person_n some_o have_v daily_o take_v 2_o 3_o 4_o 5_o 6_o dram_fw-la nay_o i_o have_v hear_v of_o some_o that_o have_v take_v a_o ounce_n a_o day_n and_o of_o one_o that_o take_v two_o ounce_n whereas_o the_o learned_a and_o curious_a dr._n edward_n smith_n can_v find_v none_o about_o smyrna_n who_o take_v above_o 3_o dram_fw-la a_o day_n all_o this_o be_v most_o agreeable_a to_o reason_n and_o the_o whole_a current_n of_o my_o discourse_n viz._n that_o it_o can_v be_v better_o bear_v in_o cold_a than_o hot_a wether_n and_o consequent_o in_o cold_a than_o hot_a climate_n by_o firm_a flesh_v person_n than_o such_o as_o have_v soft_a and_o flaccid_a flesh_n as_o the_o southern_a people_n have_v in_o comparison_n of_o the_o northern_a and_o such_o as_o inhabit_v cold_a country_n therefore_o you_o may_v be_v sure_a that_o such_o as_o inquire_v into_o the_o cause_n why_o the_o turk_n and_o other_o eastern_a people_n can_v take_v great_a quantity_n than_o we_o can_v seek_v for_o the_o reason_n of_o thing_n before_o they_o know_v the_o fact_n nay_o when_o the_o fact_n be_v quite_o contrary_a to_o what_o they_o build_v upon_o we_o may_v as_o well_o expect_v edify_v discourse_n from_o they_o that_o inquire_v why_o fire_n be_v cold_a water_n dry_a and_o the_o like_a as_o from_o such_o as_o suppose_v thing_n contrary_a to_o true_a and_o sensible_a experience_n chap._n xxix_o some_o general_a rule_n caution_n &c_n &c_n concern_v the_o use_n of_o opium_n though_o there_o be_v hardly_o any_o rule_n caution_n or_o thing_n worthy_a of_o observation_n concern_v the_o use_n of_o opium_n but_o what_o be_v imply_v or_o easy_o inferable_a from_o what_o have_v be_v say_v nor_o now_o that_o the_o true_a nature_n of_o opium_n be_v discover_v can_v there_o be_v such_o fear_n and_o jealoufy_v which_o multiply_v caution_n concern_v the_o administration_n thereof_o for_o every_o one_o may_v now_o easy_o see_v wherein_o its_o danger_n and_o benefit_n lie_v yet_o because_o a_o chapter_n of_o rule_n and_o caution_n may_v be_v expect_v as_o be_v usual_a and_o to_o have_v a_o single_a view_n of_o such_o as_o lie_v more_o scatter_v and_o not_o so_o ready_o find_v in_o the_o body_n of_o the_o book_n i_o will_v to_o introduce_v the_o use_n of_o opium_n with_o more_o clearness_n and_o perfect_a security_n give_v you_o a_o collection_n of_o general_a rule_n and_o caution_n concern_v its_o use_n whereof_o some_o be_v mention_v and_o most_o inferable_a from_o the_o premise_n i._o as_o to_o its_o substance_n 1._o it_o shall_v be_v always_o give_v free_v from_o its_o resinous_n part_n if_o you_o can_v get_v such_o a_o preparation_n 2._o it_o be_v also_o neat_a and_o convenient_a that_o it_o shall_v be_v free_v from_o all_o its_o earth_n and_o dress_n 3._o never_o give_v opium_n but_o either_o so_o prepare_v or_o with_o its_o rosin_n so_o subdue_v segregated_a or_o alter_v as_o i_o have_v show_v in_o the_o safe_a preparation_n thereof_o iâ—_n follow_v that_o 4._o crude_a opium_n and_o extract_v make_v in_o sulphureous_a spirit_n be_v utter_o to_o be_v reject_v 5._o never_o give_v it_o mix_v or_o join_v with_o resinous_a thing_n as_o have_v be_v intimate_v 6._o never_o mix_v or_o join_v it_o with_o other_o opiate_n 1._o because_o none_o of_o they_o be_v so_o good_a 2._o because_o they_o be_v not_o so_o well_o know_v 3._o because_o it_o make_v the_o do_v more_o uncertain_a 4._o because_o those_o other_o opiate_n be_v use_v unprepared_a 7._o pil._n e_o styrace_n because_o make_v of_o resinous_a opium_n join_v with_o resinous_a thing_n as_o styrax_fw-la calam_fw-la and_o olibanum_n be_v a_o insufferable_a preparation_n though_o commend_v and_o therefore_o have_v frequent_a ill_a effect_n to_o my_o knowledge_n 8._o pil._n â—_o cynoglossâ_fw-la be_v such_o another_o have_v two_o opiate_n in_o it_o beside_o opium_n extract_v out_o of_o spirit_n of_o wine_n which_o be_v far_o worse_a than_o crude_a opium_n though_o by_o the_o way_n of_o eminence_n call_v opium_n prepare_v in_o our_o dispensatory_a styrax_n calam_fw-la and_o olibanum_n which_o be_v resinous_a 9_o laudan_n lond._n be_v also_o a_o ill_a preparation_n as_o have_v the_o
part_n themselves_o do_v also_o due_o contract_n which_o opium_n hinder_v 6._o you_o have_v much_o the_o same_o reason_n not_o to_o give_v they_o soon_o after_o other_o large_a evacuation_n where_o a_o due_a contraction_n of_o the_o part_n be_v requisite_a as_o after_o tapping_n or_o paracentesis_n in_o dropsy_n childbirth_n etc._n etc._n 7._o opiate_n be_v best_a give_v in_o the_o morning_n to_o cause_n euphory_n or_o brisk_a effect_n because_o the_o refreshment_n gain_v by_o the_o night_n sleep_n do_v not_o only_o concur_v towards_o euphory_n and_o briskness_n but_o also_o much_o oppose_v sleepiness_n and_o drowsiness_n which_o be_v not_o consistent_a with_o brisk_a effect_n vi_o as_o to_o person_n 1._o it_o be_v not_o convenient_a to_o give_v opiate_n to_o person_n very_o young_a or_o very_a old_a 2._o they_o agree_v better_o with_o man_n than_o woman_n or_o child_n with_o man_n of_o a_o robu_v and_o hard_a rather_o than_o of_o a_o weak_a fine_a tender_a and_o soft_a texture_n with_o such_o as_o have_v a_o strong_a digestion_n than_o a_o weak_a and_o in_o general_a with_o the_o strong_a rather_o than_o the_o weak_a therefore_o 3._o never_o give_v they_o to_o person_n that_o be_v very_o weak_a especial_o if_o they_o take_v or_o digest_v no_o sustenance_n or_o extreme_o little_a for_o reason_n already_o give_v nor_o to_o such_o as_o be_v near_o their_o end_n or_o almost_o expire_a ☞_o except_o it_o be_v for_o want_v of_o opium_n or_o by_o extremity_n of_o contraction_n by_o terror_n pain_n cold_a convulsion_n etc._n etc._n for_o than_o it_o will_v do_v wonder_n in_o preserve_a people_n that_o be_v otherwise_o past_a all_o hope_n by_o relax_v take_v away_o pain_n contraction_n etc._n etc._n 4._o it_o be_v not_o so_o agreeable_a to_o the_o very_a fat_a or_o moist_a because_o they_o may_v be_v over-relaxed_n nor_o to_o the_o very_a lean_a and_o dry_a etc._n etc._n especial_o to_o cause_n sleep_n because_o it_o be_v apt_a to_o irritate_fw-la and_o actuate_v their_o spirit_n too_o much_o by_o which_o mean_v sleep_n be_v much_o hinder_v vii_o as_o to_o malady_n and_o disease_n etc._n etc._n i._o opiate_n be_v not_o convenient_a in_o relaxation_n as_o such_o as_o general_a palsy_n hemiphlegia_n palsy_n of_o the_o eye_n deadness_n of_o they_o dilatation_n of_o the_o pupil_n relaxation_n of_o the_o tympan_n of_o the_o ear_n of_o one_o side_n of_o the_o face_n which_o make_v the_o other_o side_n contract_n and_o and_o so_o draw_v the_o face_n awry_o for_o it_o be_v not_o a_o spasm_n or_o convulsion_n as_o man_n imagine_v of_o the_o contract_a side_n but_o a_o resolution_n of_o the_o other_o which_o permit_v the_o antagonist_n muscle_n of_o that_o side_n to_o contract_n without_o opposition_n and_o draw_v the_o face_n towards_o the_o strong_a or_o sound_a side_n relaxation_n of_o the_o uuula_fw-la or_o the_o annex_v value_n which_o last_o be_v know_v by_o snuffle_v without_o any_o other_o evident_a cause_n or_o by_o observe_v that_o it_o do_v not_o shut_v in_o sound_a u_o in_o but_o cut_z etc._n etc._n by_o itself_o relaxation_n of_o the_o larynx_n and_o windpipe_n which_o be_v know_v by_o a_o hoarse_a kind_n of_o whisper_n without_o a_o cold_a or_o any_o evident_a cause_n of_o the_o pharynx_n or_o gullet_n which_o be_v know_v by_o a_o depravation_n of_o swallow_v without_o pain_n or_o tumour_n or_o any_o evident_a cause_n a_o paralytical_a asthma_n or_o difficulty_n of_o breathe_v wherein_o man_n heave_v the_o shoulder_n without_o any_o apparent_a cause_n relaxation_n of_o the_o stomach_n as_o when_o meat_n stay_v too_o long_o at_o stomach_n etc._n etc._n a._n palsy_n of_o the_o intestine_n or_o gut_n as_o when_o one_o be_v bind_v and_o can_v refer_v it_o to_o any_o other_o cause_n of_o the_o bladder_n when_o one_o can_v make_v water_n without_o any_o other_o cause_n to_o refer_v it_o to_o relaxation_n of_o the_o sphincter_n of_o the_o bladder_n and_o anâ—_n that_o be_v when_o urine_n or_o ordure_n fall_v from_o one_o involuntary_o nor_o be_v they_o convenient_a in_o bath_n unless_o great_a relaxation_n as_o for_o passage_n of_o the_o stone_n etc._n etc._n be_v intend_v nor_o in_o rupture_n as_o bronchocele_v of_o the_o windpipe_n exomphalos_n of_o the_o navel_n bubonocele_n of_o the_o groin_n or_o the_o fall_n of_o humour_n gut_n fat_a etc._n etc._n into_o the_o scrotum_fw-la or_o of_o the_o fundament_n womb_n or_o the_o vagina_n etc._n etc._n except_o it_o be_v to_o reduce_v they_o nor_o in_o lunation_n sprain_n laxity_n and_o weakness_n of_o joint_n limb_n back_o etc._n etc._n extension_n of_o nerve_n tendon_n ligament_n etc._n etc._n nor_o where_o relaxation_n do_v or_o may_v improve_v the_o distemper_n or_o do_v harm_n as_o in_o apoplectical_a and_o soporose_a case_n as_o coma_n caros_n lethargy_n etc._n etc._n weakness_n of_o memory_n stupidity_n morosiâ—_n nightmare_n drunkenness_n etc._n etc._n syncopes_fw-la and_o faint_n from_o relaxation_n as_o the_o original_a cause_n as_o from_o excess_n of_o joy_n pleasure_n large_a evacuation_n when_o the_o part_n can_v well_o and_o due_o contract_v upon_o what_o remain_v as_o after_o childbirth_n profuse_a hemorrhage_n tapping_n or_o paracentesis_n or_o any_o large_a evacuation_n of_o humour_n in_o dropsy_n of_o the_o belly_n breast_n or_o head_n nor_o as_o have_v be_v hint_v in_o dropsy_n though_o without_o any_o such_o evacuation_n unless_o it_o be_v upon_o some_o special_a consideration_n of_o the_o learned_a nor_o in_o tremble_n or_o shake_v of_o the_o head_n or_o hand_n etc._n etc._n from_o weakness_n as_o in_o old_a age_n nor_o in_o flux_n from_o relaxation_n as_o too_o much_o sweat_n gonorrhaea_n simplex_n diabetes_n nocturnal_a pollution_n chylous_a flux_n lientery_n involuntary_a flux_n of_o urine_n or_o ordure_n and_o some_o sort_n of_o immoderate_a flux_n of_o the_o menses_fw-la or_o lochia_n which_o owe_v their_o cause_n to_o relaxation_n or_o aptitude_n to_o abortion_n from_o that_o cause_n and_o indeed_o general_o in_o woman_n with_o child_n lest_o it_o shall_v cause_v abortion_n by_o relax_v the_o neck_n of_o the_o womb._n or_o where_o contraction_n be_v beneficial_a as_o to_o empty_v a_o foul_a or_o replete_a stomach_n choler_n etc._n etc._n by_o vomit_v or_o stool_n or_o a_o ill_a humour_n any_o way_n therefore_o ii_o opiate_n be_v not_o convenient_a when_o grievous_a sensation_n be_v useful_a as_o to_o excite_v expectoration_n when_o matter_n threaten_v suffocation_n in_o vomicas_fw-la pleurisy_n peripneumonias_n consumption_n spit_v of_o blood_n etc._n etc._n when_o hunger_n call_v for_o food_n and_o restaurative_n that_o of_o stuff_v at_o stomach_n excite_v vomit_v that_o of_o urine_n solicit_v we_o to_o a_o due_a excretion_n thereof_o that_o of_o ill_a matter_n at_o gut_n cause_v a_o evacuation_n thereof_o so_o that_o when_o a_o crisis_n be_v to_o be_v by_o the_o help_n of_o grievous_a sensation_n or_o irritation_n opiate_n be_v not_o convenient_a for_o it_o take_v off_o the_o sense_n of_o irritation_n but_o when_o a_o crisis_n be_v to_o be_v by_o relaxation_n as_o by_o open_v the_o pore_n to_o cause_n sweat_n perspiration_n etc._n etc._n then_o be_v it_o of_o excellent_a use_n so_o that_o great_a question_n that_o have_v very_o much_o puzzle_v the_o learned_a whether_o opium_n be_v convenient_a before_o a_o crisis_n &_o c_o be_v plain_o and_o mechanical_o answer_v iii_o opiate_n be_v not_o convenient_a where_o titillation_n by_o the_o acrimony_n of_o volatile_a salt_n be_v the_o cause_n of_o the_o disease_n as_o in_o troublesome_a erection_n priapism_n nocturnal_a pollution_n venereal_a fury_n too_o much_o salacity_n and_o titillation_n itch_n of_o the_o uterus_fw-la scrotum_fw-la penis_n skin_n in_o general_n etc._n etc._n iv_o i_o scarce_o need_v tell_v any_o that_o opiate_n be_v inconvenient_a when_o the_o meconium_n of_o child_n shall_v be_v evacuate_v or_o when_o one_o be_v bind_v in_o body_n or_o apt_a to_o be_v so_o but_o there_o may_v be_v a_o time_n when_o the_o learned_a physician_n may_v think_v fit_a to_o give_v they_o even_o to_o the_o costive_a in_o urgent_a case_n for_o he_o can_v order_v somewhat_o along_o with_o they_o or_o soon_o after_o to_o open_v the_o body_n who_o may_v also_o see_v cause_n sometime_o to_o vary_v from_o these_o general_a rule_n when_o necessity_n and_o good_a reason_n direct_v he_o so_o to_o do_v though_o they_o be_v nevertheless_o general_a in_o their_o nature_n and_o not_o to_o be_v transgress_v without_o special_a cause_n and_o mature_a deliberation_n v._o opiate_n be_v not_o so_o convenient_a where_o there_o be_v much_o slimy_a moist_a and_o phlegmatic_a humour_n by_o reason_n that_o the_o part_n be_v subject_a in_o such_o case_n to_o be_v too_o much_o relax_v i_o have_v be_v the_o full_a especial_o upon_o the_o head_n of_o disease_n that_o i_o may_v hereafter_o have_v nothing_o to_o do_v but_o to_o show_v the_o beneficial_a use_n of_o opiate_n due_o prepare_v more_o particular_o of_o the_o panacea_n
that_o when_o people_n be_v in_o a_o untoward_a condition_n or_o as_o they_o call_v it_o out_o of_o sod_n the_o next_o day_n after_o drink_v man_n often_o advise_v take_v the_o hair_n of_o the_o same_o dog_n that_o be_v drink_v some_o of_o the_o same_o wine_n or_o liquor_n it_o be_v best_o for_o they_o to_o use_v it_o as_o i_o just_a now_o direct_v for_o their_o case_n upon_o the_o good_a effect_n of_o the_o wine_n cease_v be_v much_o like_a that_o upon_o the_o go_n off_o of_o the_o operation_n of_o opium_n which_o may_v also_o in_o this_o case_n be_v use_v instead_o of_o wine_n to_o procure_v a_o better_a and_o blither_n condition_n for_o that_o day_n that_o use_v to_o be_v very_o troublesome_a to_o drinker_n 3._o note_v that_o good_a preparation_n of_o opium_n may_v be_v convenient_o use_v to_o horse_n to_o prevent_v their_o be_v tire_v or_o take_v off_o their_o weariness_n and_o cause_v they_o to_o go_v on_o but_o i_o will_v not_o advise_v any_o preparation_n in_o this_o case_n but_o the_o liquid_a panacea_fw-la in_o good_a ale_n or_o beer_n and_o that_o only_a in_o the_o same_o quantity_n as_o be_v use_v to_o man_n till_o far_a experience_n embolden_v the_o practice_n by_o such_o mean_n i_o can_v doubt_v it_o any_o jade_n may_v be_v make_v to_o appear_v lively_a go_v well_o etc._n etc._n chap._n xxxii_o of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o compose_v the_o sensitive_a soul_n spirit_n etc._n etc._n i_o have_v show_v how_o and_o why_o it_o compose_v and_o quiet_v the_o sensitive_a soul_n spirit_n blood_n stomach_n etc._n etc._n and_o by_o that_o mean_n allay_v all_o the_o fury_n commotion_n perturbation_n and_o turbulent_a exorbitance_n thereof_o and_o that_o often_o without_o sleep_n but_o much_o better_a with_o it_o it_o follow_v therefore_o 1._o that_o it_o prevent_v and_o take_v off_o all_o fret_n and_o turbulent_a passion_n of_o the_o sensitive_a soul_n as_o anger_n uneasy_a agitation_n and_o toss_v of_o the_o mind_n peevishness_n fretfulness_n discontent_n disquietude_n dissatisfaction_n murmur_n turmoiling_n and_o vexatious_a thought_n anxiety_n solicitude_n etc._n etc._n and_o all_o the_o evil_a effect_n thereof_o as_o watch_n waste_v of_o spirit_n or_o strength_n lossitude_n hypochondriacal_a melancholy_n cachexy_n scurvy_n etc._n etc._n but_o these_o last_o belong_v most_o proper_o to_o its_o alterative_a faculty_n or_o virtue_n 2._o all_o involuntary_a furious_a agitation_n of_o the_o sensitive_a soul_n and_o spirit_n as_o madness_n more_o especial_o melancholy_a madness_n or_o such_o as_o proceed_v from_o grievous_a thought_n or_o apprehension_n loss_n cross_n despair_n fear_n terror_n or_o the_o like_a but_o they_o be_v not_o so_o good_a in_o merry_a madness_n as_o those_o from_o joy_n venereal_a fury_n and_o suchlike_a which_o answer_v the_o great_a dispute_n about_o opiate_n in_o madness_n delirium_n epileptical_a fit_n convulsion_n general_a and_o particular_a as_o those_o of_o the_o head_n rise_v of_o the_o light_n vomit_n hiccough_n sabbing_n kecking_n convulsive_a asthma_n palpitation_n and_o tremble_n of_o the_o heart_n shake_v and_o shivering_n upon_o fear_n terror_n cold_a pain_n ague-fits_a convulsive_a colick_n hysterick_n fit_v iliack_a passion_n etc._n etc._n 3._o all_o fever_n and_o fret_n of_o humour_n that_o happen_v from_o any_o of_o the_o aforesaid_a cause_n or_o from_o any_o violent_a motion_n voluntary_a or_o involuntary_a as_o labour_n run_v hew_v fight_a or_o any_o vehement_a exercise_n ratling_n toss_n concussion_n in_o coach_n wagon_n boat_n in_o stormy_a wether_n violent_a ride_v etc._n etc._n or_o from_o heat_n of_o fire_n sun_n bath_n hothouse_n bagnio_n crowd_n lie_v too_o many_o in_o one_o bed_n or_o with_o too_o much_o clothes_n or_o from_o grievous_a sensation_n irritation_n or_o pain_n as_o fever_n upon_o inflammation_n abscess_n bubo_n stone_n colic_n cardialgia_n wound_n fracture_n dislocation_n confusion_n amputation_n lithotomy_n paracentesis_n or_o any_o painful_a operation_n of_o the_o noble_a art_n of_o chirurgery_n agony_n or_o pain_n of_o the_o smallpox_n as_o its_o second_o fever_n and_o the_o like_a or_o from_o flux_n as_o tedious_a and_o turbulent_a vomit_n diarrheas_n dysentery_n cholera_n iliack_a passion_n artificial_a purge_v and_o all_o symptomatick_a or_o immaterial_a fever_n whatsoever_o which_o either_o never_o have_v any_o matter_n but_o proceed_v from_o such_o agitate_a cause_n as_o i_o mention_v or_o remain_v as_o some_o do_v after_o the_o grieve_v matter_n be_v carry_v off_o by_o vomit_v purge_v etc._n etc._n i_o forbear_v mention_v pleurisy_n and_o peripneumonia_n among_o the_o fever_n that_o it_o prevent_v or_o take_v off_o because_o there_o be_v great_a dispute_n whether_o opiate_n be_v convenient_a in_o those_o case_n which_o i_o hope_v to_o determine_v unless_o it_o be_v when_o the_o say_v distemper_n be_v come_v to_o that_o pass_n that_o it_o be_v dangerous_a to_o cause_v sleep_n or_o take_v away_o any_o of_o the_o sense_n of_o the_o irritation_n of_o the_o matter_n to_o be_v expectorate_v lest_o it_o shall_v be_v too_o much_o amass_v in_o the_o bronchias_n or_o windpipe_n and_o so_o choke_v the_o person_n i_o see_v no_o cause_n to_o forbid_v they_o any_o more_o than_o sleep_v or_o opiate_n in_o other_o inflammation_n wherein_o they_o be_v high_o beneficial_a to_o give_v ease_n cause_n sleep_n compose_v the_o spirit_n and_o take_v off_o or_o at_o least_o moderate_a the_o fever_n but_o i_o see_v many_o good_a reason_n to_o use_v they_o 1._o because_o as_o a_o sal-volatile-oleosum_a they_o reserate_v and_o resolve_v clammy_a humour_n and_o be_v so_o agreeable_a in_o principle_n as_o menstraums_n shall_v be_v to_o the_o thing_n to_o be_v resolve_v i_o can_v doubt_v but_o red_a poppy_n be_v upon_o experience_n state_v a_o specific_a in_o those_o case_n for_o that_o reason_n 2._o because_o these_o distemper_n as_o hypocrates_n speak_v be_v from_o a_o segregation_n of_o humour_n by_o agitation_n etc._n etc._n and_o opiate_n excellent_a composer_n thereof_o 3._o because_o they_o be_v such_o great_a discusser_n and_o 4._o open_v the_o pore_n to_o let_v the_o discuss_v matter_n quite_o out_o of_o the_o body_n 5._o because_o it_o may_v be_v that_o by_o its_o relaxation_n upon_o such_o resolution_n the_o lodge_v matter_n may_v be_v cause_v to_o flow_v off_o and_o circulate_v again_o and_o so_o be_v gradue_v discuss_v and_o carry_v off_o by_o the_o open_a pore_n 6._o because_o it_o envigorate_v nature_n to_o perform_v those_o thing_n and_o 7._o give_v ease_n and_o recruit_v of_o the_o spirit_n by_o sleep_n so_o that_o all_o thing_n consider_v i_o think_v as_o experience_n assure_v we_o that_o red_a poppy_n or_o opiate_n in_o due_a quantity_n be_v the_o very_o best_a remedy_n that_o can_v be_v use_v hence_o it_o be_v that_o wedelius_n call_v opium_n a_o antipleuritick_n specific_a he_o have_v observe_v as_o i_o and_o other_o have_v do_v that_o the_o whole_a course_n of_o the_o disease_n and_o expectoration_n will_v succeed_v much_o better_a by_o their_o use._n he_o add_v also_o that_o he_o have_v very_o often_o cure_v they_o by_o its_o help_n without_o let_v of_o blood_n which_o be_v a_o infallible_a sign_n of_o their_o good_a effect_n since_o the_o pleurisy_n can_v hardly_o be_v cure_v without_o bleed_v i_o can_v see_v how_o a_o effect_n that_o bear_v such_o analogy_n to_o sleep_n can_v do_v any_o more_o harm_n than_o sleep_n etmuller_n also_o advise_v the_o give_v of_o opiate_n not_o only_o in_o the_o beginning_n but_o also_o during_o the_o increase_n of_o the_o pleurisy_n or_o peripneumoniae_fw-la so_o that_o i_o conclude_v that_o they_o be_v of_o excellent_a use_n in_o those_o disease_n unless_o it_o be_v when_o sleep_n or_o they_o may_v cause_v too_o much_o insensibleness_n of_o the_o bronchias_n and_o so_o retard_v expectoration_n when_o the_o case_n be_v such_o that_o the_o want_v thereof_o may_v endanger_v the_o person_n be_v be_v choke_v we_o have_v also_o many_o history_n of_o person_n cure_v in_o other_o fever_n by_o large_a dose_n of_o opiate_n i_o suppose_v that_o resinous_a opiate_n cause_v vomit_v and_o great_a disturbance_n by_o reason_n of_o ill_a digestion_n in_o those_o case_n may_v be_v one_o great_a cause_n of_o people_n fear_n and_o jeolousy_n in_o give_v opiate_n which_o be_v easy_o prevent_v by_o give_v liquid_a opiate_n void_a of_o any_o resinous_a particle_n as_o the_o liquid_a panacea_fw-la etc._n etc._n 4._o it_o do_v by_o compose_v quiet_v and_o appease_v the_o motion_n and_o perturbation_n of_o the_o blood_n conduce_v much_o to_o the_o stop_n of_o its_o efflux_n in_o hemorrhage_n or_o bleeding_n that_o be_v unnatural_a as_o at_o nose_n in_o spit_v and_o vomit_v of_o blood_n bleed_v at_o the_o hemorrhoid_v in_o dysentery_n piss_v of_o blood_n etc._n etc._n and_o sometime_o in_o profuse_a menses_fw-la when_o they_o happen_v from_o a_o fever_n or_o too_o much_o motion_n of_o the_o blood_n and_o
spirit_n and_o not_o a_o over-relaxation_n or_o dilatation_n of_o the_o pore_n which_o must_v be_v well_o distinguish_v i._o the_o form_n must_v be_v liquid_a in_o all_o fever_n and_o be_v also_o most_o convenient_a general_o speak_v ii_o the_o do_v may_v be_v the_o moderate_a or_o middling_a except_o it_o be_v where_o the_o pain_n be_v great_a or_o where_o much_o of_o the_o opiate_n be_v lose_v as_o in_o vomit_v looseness_n etc._n etc._n for_o which_o see_v the_o general_n rule_v iii_o the_o vehicle_n shall_v be_v general_o speak_v cool_v compose_v and_o incrassate_v liquid_n as_o emulsion_n milk_n and_o water_n or_o the_o like_a but_o in_o settle_v the_o stomach_n use_v agreeable_a warm_a and_o comfortable_a cordial_n or_o wine_n burn_v with_o aromatics_n or_o the_o like_a iv_o the_o time_n be_v when_o it_o be_v convenient_a according_a to_o the_o general_n rule_v and_o your_o intention_n of_o its_o operation_n therefore_o where_o there_o be_v periodical_a paroxysm_n or_o exacerbation_n as_o in_o the_o smallpox_n and_o many_o disease_n in_o the_o afternoon_n or_o towards_o the_o evening_n give_v it_o the_o due_a time_n before_o that_o it_o may_v have_v its_o full_a effect_n by_o the_o time_n the_o paroxysm_n or_o exacerbation_n be_v expect_v to_o begin_v and_o be_v not_o so_o mad_a as_o to_o be_v regulate_v by_o night_n or_o day_n or_o bedtime_n etc._n etc._n as_o be_v usual_a which_o be_v no_o symptom_n sign_n or_o effect_n of_o the_o distemper_n but_o of_o the_o motion_n or_o position_n of_o the_o sun_n star_n &c_n &c_n which_o be_v not_o the_o subject_n of_o your_o cure_n nor_o can_v be_v the_o want_n of_o which_o most_o obvious_a and_o rational_a practice_n have_v sad_o disappoint_v inconsiderate_a physician_n and_o often_o hazard_v if_o not_o destroy_v the_o patient_n v._o the_o regimen_n be_v the_o same_o as_o that_o to_o cause_v sleep_n which_o you_o have_v in_o chap._n 35._o and_o shall_v be_v by_o all_o mean_v use_v in_o this_o case_n 1._o note_v that_o opiate_n be_v not_o to_o be_v use_v as_o have_v be_v intimate_v where_o the_o commotion_n flux_n etc._n etc._n be_v for_o apparent_a and_o speedy_a benefit_n of_o nature_n as_o in_o vomit_v upon_o repletion_n or_o to_o discharge_v the_o stomach_n of_o somewhat_o that_o offend_v it_o or_o a_o looseness_n to_o clear_v the_o intestine_n or_o the_o like_a 2._o note_v that_o when_o any_o evacuation_n be_v to_o be_v make_v by_o vomit_n or_o stool_n the_o best_a way_n in_o these_o case_n be_v to_o use_v large_a dilution_n of_o some_o contemperate_a liquid_a instead_o of_o vomitory_n and_o purger_n therefore_o use_v only_o lukewarm_a water_n or_o which_o be_v best_a boil_v with_o a_o little_a carduus_fw-la in_o it_o or_o carduus-posset_n or_o the_o like_a to_o cause_v vomit_v and_o more_o agreeable_a dilution_n for_o the_o intestine_n to_o wash_v off_o ill_a humour_n as_o a_o gallon_n of_o water_n with_o half_a a_o ounce_n of_o cream_n of_o tartar_n or_o rather_o the_o purge_a salt_n of_o the_o water_n dissolve_v in_o it_o or_o some_o part_n thereof_o use_v all_o cold_a or_o but_o very_o little_o warm_v give_v the_o opiate_n or_o panacea_fw-la immediate_o after_o the_o person_n have_v do_v vomit_v or_o purge_v in_o a_o small_a glass_n of_o wine_n or_o agreeable_a cordial_n to_o warm_v and_o comfort_v the_o stomach_n and_o intestine_n which_o because_o of_o the_o smallness_n of_o the_o quantity_n the_o moisture_n and_o coolness_n of_o the_o dilute_a liquid_n and_o the_o opiate_n can_v cause_v no_o inconvenience_n by_o its_o inconsiderable_a heat_n chap._n xxxiii_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o relax_v have_v show_v that_o opiate_n relax_v all_o the_o sensile_a part_n of_o the_o body_n and_o bow_n and_o why_o it_o follow_v that_o they_o be_v of_o excellent_a use_n 1._o to_o prevent_v and_o take_v away_o all_o contraction_n that_o happen_v from_o grievous_a passion_n or_o sensation_n or_o pain_n as_o convulsion_n sâ—iverings_n shake_v cramp_n tension_n palpitation_n and_o tremor_n of_o the_o heart_n from_o fear_n terror_n grief_n melancholy_n anxiety_n solicitude_n anger_n fretfulness_n concern_v surprise_v etc._n etc._n or_o from_o cold_a pain_n acid_n etc._n etc._n as_o contraction_n of_o the_o sphincter_n of_o the_o bladder_n from_o those_o cause_n by_o which_o the_o urine_n be_v often_o stop_v as_o also_o by_o the_o pain_n from_o the_o haemorrhoid_v inflammation_n small_a pox_n colick_n acrimony_n excoriation_n etc._n etc._n which_o often_o hinder_v the_o make_n of_o water_n as_o they_o also_o do_v sometime_o go_v to_o stool_n swallow_v etc._n etc._n shiver_a in_o ague-fits_a stupor_n from_o cold_a or_o pain_v which_o as_o be_v show_v proceed_v from_o a_o violent_a contraction_n in_o all_o which_o it_o will_v scarce_o ever_o fail_v of_o due_a effect_n by_o this_o mean_v you_o may_v as_o i_o have_v often_o do_v cure_v those_o disaster_n safe_o speedy_o and_o pleasant_o even_o to_o a_o wonder_n and_o amazement_n as_o if_o charm_v by_o a_o spell_n when_o other_o know_v not_o what_o hand_n to_o put_v to_o they_o and_o be_v quite_o baffle_v thereby_o by_o the_o same_o mean_n though_o little_a or_o not_o at_o all_o mind_a you_o may_v prevent_v great_a tumor_n upon_o pain_n as_o when_o by_o a_o thorn_n or_o any_o grievous_a pain_n the_o arm_n leg_n thigh_n etc._n etc._n begin_v to_o swell_v for_o the_o swell_a which_o often_o grow_v prodigious_o and_o seize_v the_o whole_a limb_n if_o not_o a_o great_a part_n of_o the_o body_n threaten_v and_o often_o cause_v mortification_n and_o death_n itself_o be_v cause_v by_o the_o pain_n contract_v and_o so_o gird_v the_o part_n that_o the_o blood_n lympha_fw-la &c._n &c._n can_v pass_v by_o which_o mean_v the_o humour_n be_v stagnate_v and_o crowd_v in_o by_o the_o force_n of_o the_o artery_n and_o damn_v up_o by_o the_o contraction_n most_o dreadful_a tumor_n happen_v whereas_o the_o pain_n be_v take_v away_o by_o the_o opiate_n and_o all_o the_o part_n relax_v they_o be_v and_o must_v be_v prevent_v by_o plain_a mechanism_n if_o use_v timely_a for_o pain_n can_v cause_v tumor_n by_o no_o other_o mean_n beside_o contraction_n which_o opium_n must_v prevent_v by_o take_v away_o the_o very_a pain_n itself_o 2._o to_o help_v the_o cure_n of_o all_o other_o contraction_n as_o tension_n rigidity_n of_o nerve_n membrane_n tendon_n ligament_n muscle_n etc._n etc._n 3._o to_o relax_v or_o make_v way_n for_o thing_n to_o pass_v as_o sweat_v 〈◊〉_d small_a pox_n measles_n pestilential_a or_o venomous_a esslâ—vias_n mâ—nses_n lochia_n and_o the_o like_a to_o pass_v through_o the_o skin_n or_o pore_n a_o child_n dead_z or_o alive_a afterbirth_n mole_n clod_v blood_n etc._n etc._n to_o pass_v through_o the_o neck_n of_o the_o womb_n when_o too_o narrow_a by_o nature_n or_o contract_v by_o pain_n cold_a terror_n etc._n etc._n a_o stone_n to_o pass_v the_o ureter_n or_o neck_n of_o the_o bladder_n by_o take_v away_o the_o pain_n that_o contract_v they_o and_o hinder_v the_o passage_n of_o the_o stone_n so_o that_o in_o the_o hand_n of_o a_o ingenious_a physician_n there_o be_v not_o a_o better_a nor_o as_o good_a a_o remedy_n to_o cause_v a_o stone_n of_o any_o passable_a bigness_n to_o come_v away_o for_o it_o pass_v through_o the_o relaxed_a or_o widen_v passage_n without_o pain_n to_o help_v which_o other_o relaxer_n as_o warmth_n 〈◊〉_d bathâ—_n fomentation_n clyster_n together_o with_o slippery_a and_o emollient_a thing_n inward_o take_v and_o at_o last_o a_o great_a stream_n of_o urine_n well_o contrive_v and_o time_v when_o the_o part_n be_v most_o relax_v supple_v and_o lubricate_v do_v much_o conduce_v i_o will_v have_v all_o who_o be_v trouble_v with_o the_o stone_n note_v this_o note_v also_o that_o to_o hold_v and_o dam_v up_o the_o urine_n a_o long_a time_n be_v of_o excellent_a use_n well_o manage_v when_o the_o stone_n be_v in_o the_o ureter_n because_o when_o the_o urine_n have_v fill_v up_o the_o bladder_n very_o tight_o that_o it_o will_v receive_v no_o more_o it_o must_v distend_v the_o ureter_n which_o be_v the_o cause_n that_o very_o many_o be_v ease_v either_o by_o the_o removal_n or_o discharge_v of_o the_o stone_n after_o a_o set_a time_n which_o give_v occasion_n to_o call_v they_o fit_v of_o the_o stone_n because_o they_o last_o for_o much_o about_o the_o same_o length_n of_o time_n however_o the_o large_a and_o sudden_a evacuation_n of_o urine_n must_v by_o leave_v the_o part_n loose_a etc._n etc._n conduce_v very_o much_o to_o the_o passage_n of_o the_o stone_n clod_n of_o blood_n phlegm_n matter_n etc._n etc._n that_o step_v the_o urine_n 4._o to_o relax_v or_o make_v way_n for_o thing_n to_o be_v put_v into_o the_o body_n when_o there_o be_v occasion_n as_o in_o reduction_n of_o hernias_fw-la or_o rupture_n of_o a_o fall_v fundament_n womb_n or_o
vagina_n in_o which_o case_n it_o be_v of_o neat_a use_n both_o by_o relax_v and_o take_v away_o pain_n during_o the_o operation_n it_o may_v be_v also_o of_o use_n when_o the_o strictness_n of_o the_o collum_n uteri_fw-la hinder_v the_o admission_n of_o sem._n viril_n both_o as_o a_o general_a relaxer_n and_o as_o cause_v great_a pleasure_n of_o those_o part_n and_o a_o proportionable_a relaxation_n thereof_o for_o it_o be_v by_o the_o pleasure_n in_o coition_n that_o the_o collum_n uteri_fw-la be_v open_v or_o relax_v as_o be_v observe_v which_o immediate_o close_v again_o when_o the_o sense_n of_o pleasure_n be_v end_v yea_o and_o so_o much_o the_o strict_a because_o the_o loss_n of_o pleasure_n be_v as_o be_v show_v a_o kind_a of_o grievance_n hence_o it_o be_v that_o omne_fw-la animal_n post_fw-la coitum_fw-la est_fw-la triste_fw-fr and_o not_o because_o of_o loss_n of_o spirit_n as_o be_v vulgar_o imagine_v for_o we_o can_v lose_v little_a or_o no_o spirit_n by_o that_o which_o be_v so_o separate_v for_o excretion_n before_o hand_n as_o the_o semen_n be_v 5._o to_o enlarge_v any_o part_n for_o the_o due_a reception_n of_o what_o be_v convenient_a or_o necessary_a as_o the_o breast_n to_o receive_v milk_n by_o which_o mean_v it_o come_v to_o be_v such_o great_a increaser_n of_o milk_n the_o seminal_a vessel_n as_o sem._n virile_a do_v upon_o puberty_n to_o receive_v the_o semen_n thus_o it_o cause_v the_o penis_n to_o grow_v as_o the_o semen_n upon_o puberty_n cause_v it_o and_o cock_n comb_n turkeycock_n red_a bag_n at_o the_o neck_n proboscis_n etc._n etc._n to_o grow_v as_o the_o time_n they_o be_v fit_a for_o or_o begin_v to_o tread_v for_o the_o relaxation_n cause_v by_o the_o pleasure_n of_o the_o semen_n make_v the_o party_n more_o capable_a of_o the_o nutriment_n thus_o it_o be_v that_o sleep_v cause_n the_o growth_n fatten_v and_o thrive_a of_o animal_n and_o red_a nose_n to_o grow_v so_o large_a by_o frequent_a relaxation_n upon_o the_o pleasure_n of_o wine_n ale_z etc._n etc._n as_o be_v say_v to_o which_o quantity_n distend_v the_o part_n may_v in_o the_o last_o mention_v case_n contribute_v i._o the_o form_n of_o opiate_n in_o this_o case_n may_v be_v either_o solid_a or_o liquid_a as_o you_o think_v â—it_a ii_o the_o dose_n must_v be_v proportion_v to_o the_o relaxation_n that_o you_o desire_v for_o more_o relax_n more_o and_o less_o less_o so_o must_v it_o be_v also_o proportion_v to_o the_o contraction_n that_o it_o be_v to_o take_v away_o therefore_o very_o grievous_a passion_n or_o sensation_n which_o cause_n proportionable_a contraction_n require_v great_a dose_n because_o their_o grievance_n and_o contraction_n do_v strong_o oppose_v the_o pleasure_n and_o relaxation_n that_o opiate_n cause_n therefore_o great_a pain_n as_o you_o will_v find_v in_o its_o due_a place_n require_v a_o extraordinary_a do_v iii_o the_o vehicle_n in_o contraction_n from_o grievous_a passion_n shall_v be_v wine_n or_o some_o comfortable_a cordial_n except_o they_o be_v the_o more_o turbulent_a passion_n as_o anger_n fury_n etc._n etc._n where_o composer_n as_o emulsion_n milk_n and_o water_n etc._n etc._n be_v best_a in_o all_o other_o case_n emollient_a and_o supply_a vehicles_n be_v most_o proper_a as_o soft_a smooth_a and_o slippery_a 〈◊〉_d broth_n etc._n etc._n iv_o the_o time_n to_o give_v they_o be_v at_o the_o due_a distance_n before_o bed_n time_n when_o the_o intention_n be_v consistent_a with_o sleep_n which_o itself_o be_v a_o great_a relaxer_n otherwise_o any_o time_n will_v serve_v as_o occasion_n or_o the_o intention_n of_o the_o physician_n require_v it_o v._o the_o regimen_n 1._o as_o to_o meat_n and_o drink_n be_v use_v moist_a emollient_a and_o lubricate_a thing_n as_o smooth_a broth_n somewhat_o â—at_a butter_v root_n herb_n sauce_n 〈◊〉_d milk-meat_n young_a flesh_n as_o of_o roast_a pig_n 〈◊〉_d lamb_n etc._n etc._n smooth_a drink_n as_o alc_n 〈◊〉_d etc._n etc._n 2._o as_o to_o sleep_v and_o wake_v that_o relax_n and_o this_o contract_n therefore_o that_o conduce_v this_o hinder_v 3._o as_o to_o rest_n and_o motion_n that_o relax_n and_o this_o contract_n 4._o as_o to_o the_o passion_n of_o the_o mind_n the_o pleasant_a as_o 〈◊〉_d joy_n pleasure_n comfort_n and_o all_o such_o do_v relax_v and_o the_o grievous_a as_o terror_n fear_v grief_n melancholy_n etc._n etc._n contract_n as_o pain_n do_v 5._o as_o to_o air_n the_o warm_a and_o moist_a or_o that_o when_o the_o quicksilver_n be_v low_a in_o the_o barometer_n or_o weatherglass_n do_v relax_v as_o do_v warm_a bath_n fomentation_n etc._n etc._n especial_o if_o emollient_a dry_v and_o cold_a air_n and_o that_o when_o the_o quicksilver_n be_v high_a do_v cause_n contraction_n 6._o as_o to_o excretion_n and_o retention_n general_o excretion_n do_v make_v room_n and_o way_n for_o thing_n to_o pass_v through_o or_o into_o the_o relaxed_a part_n as_o clyster_v for_o passage_n of_o the_o stone_n child_n reduction_n of_o hernias_fw-la etc._n etc._n but_o be_v sure_a not_o to_o make_v the_o excretion_n grievous_a because_o all_o grievous_a sensation_n cause_v contraction_n chap._n xxxiv_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o take_v away_o pain_n or_o grievous_a sensation_n this_o it_o do_v as_o be_v show_v by_o divert_v the_o sensitive_a soul_n and_o introduce_v a_o sense_n of_o pleasure_n which_o be_v contrary_a to_o grievous_a sensation_n or_o pain_n can_v be_v in_o the_o same_o subject_a with_o pain_n but_o chief_o and_o mechanical_o by_o relax_v all_o part_n and_o permit_v the_o springy_a animal_n spirit_n to_o expand_v and_o so_o become_v unfit_a to_o carry_v impression_n smart_o which_o be_v requisite_a to_o cause_v a_o sense_n of_o pain_n as_o have_v be_v prove_v therefore_o it_o be_v of_o most_o happy_a and_o glorious_a use_n in_o all_o pain_n but_o especial_o to_o be_v use_v 1._o in_o such_o as_o be_v not_o for_o any_o benefit_n to_o the_o person_n pain_v in_o order_n to_o alter_v or_o evacuate_v the_o grieve_v cause_n as_o in_o pocky_a scorbutical_a or_o hypochondriacal_a pain_n or_o such_o as_o proceed_v from_o any_o ill_a habit_n of_o body_n etc._n etc._n 2._o where_o pain_n hinder_v the_o take_v away_o of_o its_o cause_n or_o some_o benefit_n as_o when_o the_o pain_n of_o the_o stone_n do_v by_o contract_v the_o part_n hinder_v its_o own_o passage_n that_o of_o a_o tenesmus_n hinder_v go_v to_o stool_n that_o of_o the_o sphincter_n of_o the_o bladder_n hinder_v its_o open_n to_o let_v out_o urine_n clod_v blood_n phlegm_n matter_n or_o any_o such_o thing_n when_o that_o of_o the_o neck_n of_o the_o wâ—mb_n hinder_v delivery_n of_o a_o child_n afterbirth_n mole_n clod_v blood_n etc._n etc._n that_o of_o the_o mouth_n of_o the_o stomach_n hinder_v vomit_v when_o requisite_a or_o that_o of_o the_o pylorus_n hinder_v the_o detrusion_n of_o chyle_n or_o that_o of_o the_o intestine_n as_o by_o a_o inflammation_n etc._n etc._n stop_v the_o passage_n of_o the_o ordure_n and_o cause_v a_o iliack_a passion_n or_o that_o of_o the_o guilet_n hinder_v swollow_v of_o the_o larynx_n breathe_v or_o that_o of_o any_o part_n hinder_v perspiration_n or_o desire_a sweat_n or_o that_o of_o the_o venereal_a part_n stop_v the_o menses_fw-la or_o lochia_n etc._n etc._n in_o all_o which_o case_n it_o be_v and_o must_v in_o all_o reason_n be_v of_o excellent_a and_o if_o due_o manage_v of_o almost_o if_o not_o altogether_o infallible_a effect_n by_o take_v away_o the_o pain_n which_o cause_v the_o part_n to_o contract_v and_o make_v the_o stop_n etc._n etc._n 3._o where_o the_o cause_n of_o the_o pain_n can_v be_v remove_v but_o by_o perspiration_n sweat_v menses_fw-la lochia_n or_o urine_n â—s_n in_o pain_n in_o the_o habit_n of_o the_o body_n limb_n etc._n etc._n from_o cold_a wind_n or_o vapour_n gout_n rheumatism_n stitch_n pleurisy_n inflammation_n and_o many_o of_o the_o case_n aforemention_v it_o be_v excellent_a as_o it_o be_v 4._o where_o the_o pain_n irritation_n or_o grievous_a sensation_n cause_v nature_n to_o work_v irregular_o as_o in_o iliack_n â—_z hysterick_a fit_n fruitless_a convulsion_n canine_a apâ—_n etc._n etc._n in_o which_o case_n it_o excel_v all_o other_o mean_n for_o many_o reason_n 5._o where_o the_o pain_n be_v not_o likely_a to_o have_v a_o timely_a effect_n for_o good_a till_o people_n may_v be_v too_o much_o wear_v out_o 6._o in_o all_o pain_n that_o have_v not_o any_o material_a cause_n from_o the_o â—_z &c._n &c._n of_o the_o body_n as_o such_o as_o happen_v from_o passion_n wound_n prick_v of_o nerve_n tendon_n fracture_n dislocation_n amputation_n severe_a chirurgical_a operation_n etc._n etc._n 7._o in_o all_o pain_n from_o inflammation_n suppuration_n abseess_n tumour_n where_o repulsion_n be_v not_o convenient_a or_o possible_a 8._o in_o all_o pain_n that_o be_v more_o likely_a to_o cause_v fever_n than_o any_o