for_o because_o these_o two_o medicine_n be_v confect_v of_o many_o simples_n not_o great_o differ_v they_o have_v many_o thing_n common_a so_o as_o y_z t_z which_o be_v of_o y_z e_z one_o affirm_v may_v be_v apply_v to_o the_o other_o notwithstanding_o as_o in_o the_o number_n &_o nature_n of_o y_fw-fr e_o simples_n they_o do_v not_o in_o all_o point_n agree_v so_o no_o doubt_n in_o y_z e_z age_n of_o these_o medicine_n some_o difference_n be_v to_o be_v allot_v yet_o such_o as_o a_o man_n exercise_v in_o these_o matter_n may_v easy_o supply_v for_o in_o that_o theriacle_n have_v in_o it_o the_o flesh_n of_o viper_n and_o a_o great_a portion_n of_o opium_n then_o be_v in_o mithridatium_n it_o be_v certain_a that_o theriacle_n require_v a_o long_a time_n to_o his_o concoction_n for_o the_o flesh_n of_o viper_n must_v have_v perfect_a fermentation_n with_o the_o simples_n for_o his_o correction_n in_o like_a sort_n opium_n do_v ask_v a_o long_a time_n of_o fermentation_n &_o for_o y_o t_o cause_n galen_n 12._o the_o method_n medend_n say_v y_z t_z philonium_fw-la be_v not_o to_o be_v use_v in_o a_o year_n after_o it_o be_v compound_v and_o that_o the_o use_n of_o it_o after_o ij_o iij._n or_o iiij_o year_n be_v more_o without_o danger_n whereby_o he_o geve_v we_o to_o understande_v that_o medicine_n which_o do_v receive_v opium_n require_v long_o time_n of_o fermentation_n so_o that_o theriacle_n receive_v a_o great_a portion_n of_o opium_n than_o mithridatium_n aught_o to_o have_v a_o large_a space_n to_o be_v concoct_v than_o it_o now_o if_o theriacle_n have_v his_o perfection_n in_o one_o year_n sure_o mithridatium_n be_v thorough_o ferment_v in_o six_o month_n and_o may_v be_v keep_v in_o good_a strength_n not_o only_o as_o some_o have_v write_v to_o three_o or_o four_o year_n but_o to_o x_o or_o xij_o year_n and_o except_o we_o shall_v to_o such_o time_n prorogue_v his_o old_a age_n there_o will_v be_v no_o proportion_n in_o y_z e_z time_n for_o if_o theriacle_n be_v coct_v in_o one_o year_n do_v last_o to_o 20._o year_n before_o it_o do_v wax_v old_a sure_o by_o the_o like_a proportion_n mithridatium_n not_o well_o ferment_v under_o six_o month_n may_v just_o be_v say_v to_o continue_v in_o good_a efficacy_n to_o 10._o or_o 12._o year_n and_o as_o theriacle_n after_o 20._o year_n wax_v old_a &_o feeble_a so_o mithridatium_n after_o 10._o or_o 12._o year_n do_v decline_v that_o be_v 20._o year_n old_a be_v then_o decay_a and_o of_o little_a force_n as_o we_o may_v probable_o determine_v these_o time_n so_o there_o can_v be_v no_o certainty_n set_v to_o lead_v we_o to_o the_o time_n for_o if_o the_o simples_n be_v not_o in_o good_a perfection_n or_o the_o same_o orderly_a and_o well_o according_a to_o art_n compound_v or_o otherways_o the_o medicine_n not_o well_o keep_v than_o it_o will_v soon_o wax_v old_a &_o lose_v his_o strength_n but_o as_o galen_n write_v to_o these_o great_a medicine_n great_a care_n must_v be_v have_v of_o the_o choice_n of_o y_fw-fr e_o simples_n that_o they_o may_v be_v have_v in_o y_fw-es e_fw-es ready_a perfection_n and_o like_o diligence_n must_v be_v gieven_v that_o the_o confectioner_n may_v in_o all_o point_n do_v his_o duty_n not_o in_o make_v only_o but_o also_o in_o keep_v y_o e_o medicine_n and_o therefore_o prince_n be_v great_o to_o be_v commend_v which_o do_v by_o their_o authority_n provide_v that_o these_o medicine_n may_v be_v well_o order_v and_o for_o that_o many_o do_v in_o these_o day_n procure_v mithridatium_n to_o have_v it_o in_o their_o house_n ready_a to_o use_v it_o be_v good_a to_o know_v y_z t_o it_o be_v best_o keep_v in_o vessel_n of_o glass_n of_o silver_n and_o of_o gold_n and_o that_o it_o be_v not_o so_o good_a to_o keep_v y_z e_o same_o in_o tin_n vessel_n for_o that_o they_o be_v often_o corrupt_v with_o lead_v and_o gather_v a_o ceruse_n matter_n as_o galen_n write_v in_o his_o first_o book_n de_fw-mi antid_v i_o wish_v therefore_o that_o the_o merchant_n may_v hereof_o be_v admonish_v which_o do_v common_o bring_v theriacle_n from_o venice_n in_o vessel_n of_o lead_v whereby_o no_o small_a danger_n may_v grow_v in_o so_o noble_a a_o medicine_n &_o so_o great_o esteem_v so_o we_o must_v not_o fill_v the_o vessel_n to_o the_o top_n as_o we_o say_v brim_n full_a but_o leave_v some_o reasonable_a space_n for_o the_o medicine_n to_o work_v to_o exhale_v &_o breath_n and_o for_o that_o cause_n galen_n counsele_v to_o open_v the_o vessel_n sometime_o how_o to_o know_v good_a mithridatium_n we_o do_v read_v in_o y_z e_z book_n of_o galen_n de_fw-fr theriaca_fw-la ad_fw-la pisonem_fw-la &_o in_o his_o book_n the_o antidote_n how_o diligent_o he_o labour_v to_o gieve_v certain_a note_n and_o rule_n how_o a_o man_n may_v know_v the_o goodness_n of_o theriacle_n and_o when_o the_o same_o be_v perfect_a and_o so_o do_v in_o those_o his_o work_n set_v down_o both_o rule_n and_o proof_n thereof_o so_o careful_a in_o old_a time_n writer_n be_v that_o we_o may_v be_v assure_v of_o the_o goodness_n of_o these_o noble_a medicine_n serve_v in_o so_o great_a affect_n and_o in_o such_o common_a use_n but_o such_o be_v y_fw-fr â—_o malice_n of_o many_o which_o seek_v gain_v that_o of_o the_o great_a price_n a_o thing_n be_v the_o more_o sophistication_n they_o use_v in_o it_o y_z t_z if_o mean_n be_v not_o declare_v to_o discern_v the_o good_a from_o the_o bad_a the_o sophisticated_a from_o y_z e_z true_a no_o man_n may_v assure_v himself_o of_o the_o certainty_n of_o any_o thing_n in_o estimation_n it_o be_v therefore_o very_o necessary_a to_o show_v how_o man_n may_v know_v when_o mithridatium_n be_v good_a and_o perfect_a and_o when_o the_o same_o be_v naught_o &_o corrupt_v and_o for_o y_fw-fr â—_o galen_n in_o his_o foresay_a book_n have_v labour_v to_o declare_v this_o in_o theriacle_n we_o will_v apply_v the_o same_o to_z y_z e_z examination_n of_o mithridatium_n for_o in_o y_z t_z these_o medicine_n have_v a_o great_a affinity_n they_o do_v in_o most_o thing_n so_o concur_v that_o y_o e_o same_o which_o be_v say_v of_o y_fw-fr e_o one_o may_v be_v apply_v to_o y_z e_z other_o first_o therefore_o in_o consistence_n of_o substance_n if_o mithridatium_n be_v well_o and_o artificial_o compound_v it_o ought_v to_o have_v a_o equality_n of_o substance_n not_o dry_a nor_o over_o liquid_a and_o moist_a not_o to_o arise_v in_o clot_n and_o lump_n but_o it_o must_v be_v in_o substance_n coherent_a equal_a and_o smooth_a in_o smell_v it_o must_v resemble_v the_o simples_n whereof_o it_o be_v make_v and_o yet_o not_o to_o offer_v to_o the_o nose_n the_o smell_n of_o any_o one_o simple_a above_o the_o rest_n but_o to_o yield_v a_o common_a odour_n arise_v by_o fermentation_n of_o all_o the_o simples_n not_o peculiar_a to_o any_o one_o nor_o ungrateful_a but_o answerable_a to_o the_o ingredience_n resemble_v no_o rottenness_n nor_o mustiness_n in_o like_a sort_n the_o taste_n must_v not_o express_v any_o one_o simple_a but_o be_v as_o a_o common_a sapore_fw-la result_v of_o all_o the_o simples_n so_o that_o if_o in_o taste_v of_o mithridatium_n you_o may_v manifest_o discern_v or_o descry_v any_o one_o simple_a in_o it_o sure_o that_o mithridatium_n be_v not_o well_o confect_v therefore_o it_o may_v not_o have_v in_o it_o any_o excess_n of_o ungrateful_a bitterness_n which_o do_v sometime_o happen_v when_o the_o confectioner_n do_v either_o take_v honey_n overold_v or_o boil_v y_z e_o same_o overmuch_o so_o it_o may_v not_o show_v to_o the_o taste_n any_o sourness_n which_o happen_v if_o the_o wine_n use_v be_v not_o well_o choose_v or_o not_o well_o handle_v in_o the_o compound_v it_o seem_v that_o andromachus_n in_o his_o theriacle_n have_v a_o great_a care_n of_o the_o colour_n of_o it_o and_o for_o that_o cause_n only_o as_o some_o do_v write_v do_v add_v vitriol_n prepare_v to_o yield_v to_o it_o a_o exact_a blackness_n but_o mithridates_n attend_v rather_o the_o goodness_n then_o by_o colour_n to_o please_v y_z e_o eye_n have_v no_o such_o care_n of_o the_o colour_n and_o so_o be_v think_v to_o put_v nothing_o into_o mithridatium_n to_o gieve_v it_o any_o fresh_a colour_n than_o the_o simples_n will_v yield_v notwithstanding_o mithridatium_n true_o make_v have_v his_o colour_n convenient_a arise_v of_o the_o simples_n which_o ought_v to_o be_v a_o little_a redness_n decline_v to_o yellowness_n which_o colour_n after_o due_a fermentation_n do_v appear_v with_o some_o freshness_n &_o by_o time_n in_o keep_v the_o same_o do_v decline_v to_o a_o obscure_a darkness_n although_o at_o y_z e_z first_o it_o may_v be_v think_v hard_a to_o judge_v of_o mithridatium_n by_o these_o sign_n yet_o after_o a_o man_n be_v exercise_v in_o
in_o the_o confection_n of_o theriacle_n than_o it_o follow_v that_o when_o like_a quantity_n of_o both_o be_v take_v as_o for_o example_n Ê’_n j_o sure_o a_o great_a portion_n of_o every_o one_o simple_a be_v take_v in_o mithridatium_n and_o lesser_a in_o theriacle_n the_o lesser_a quantity_n must_v needs_o have_v lesser_a strength_n in_o remedy_v other_o poison_n save_o that_o to_o the_o which_o the_o base_a or_o ground_n do_v call_v they_o so_o it_o remain_v firm_a that_o galen_n write_v as_o observe_v in_o his_o time_n that_o theriacle_n be_v in_o deed_n better_o than_o mithridatium_n in_o bite_v of_o viper_n and_o like_a beast_n and_o that_o mithridatium_n excead_v other_a in_o remedy_v all_o other_o poison_v take_v into_o the_o body_n and_o inward_a disease_n wherefore_o in_o this_o our_o country_n where_o no_o such_o peril_n and_o danger_n be_v of_o viper_n mithridatium_n by_o good_a reason_n ought_v to_o be_v repute_v of_o great_a estimation_n than_o theriacle_n of_o the_o composition_n of_o mithridatium_n it_o shall_v not_o be_v amiss_o in_o this_o place_n to_o declare_v the_o composition_n of_o this_o medicine_n and_o it_o be_v to_o be_v note_v that_o where_o all_o writer_n do_v great_o commend_v it_o yet_o certain_a it_o be_v that_o they_o do_v not_o in_o one_o sort_n describe_v the_o make_n of_o the_o same_o but_o almost_o every_o authore_fw-la have_v a_o several_a description_n differ_v in_o the_o number_n of_o the_o simples_n and_o also_o in_o y_z e_z proportion_n and_o quantity_n in_o time_n past_o y_fw-fr e_o apothecary_n in_o make_v of_o mithridatium_n follow_v most_v the_o description_n of_o nicolaus_n praepositus_fw-la of_o auicenna_n and_o of_o nicolaus_n mirepsicus_n some_o of_o aetius_n some_o of_o paulus_n the_o former_a description_n contain_v above_o one_o hundred_o simples_n be_v long_o and_o laborious_a and_o require_v many_o supply_n for_o simples_n unknowen_a wherefore_o in_o these_o our_o late_a day_n in_o which_o learned_a man_n have_v examine_v every_o thing_n perfect_o the_o most_o part_n have_v commend_v one_o of_o y_fw-fr e_o three_o composition_n express_v by_o galen_n in_o 2._o de_fw-la antid_v of_o the_o which_o two_o be_v take_v as_o galen_n write_v out_o of_o the_o book_n of_o andromachus_n the_o first_o find_v without_o name_n be_v attribute_v to_o andromachus_n as_o compound_v by_o he_o of_o other_o suppose_v the_o very_a same_o which_o be_v find_v in_o the_o closert_n of_o king_n mithridates_n &_o after_o transcribe_v in_o the_o work_n of_o andromachus_n the_o second_o description_n be_v also_o recite_v out_o of_o andromachus_n book_n under_o the_o name_n of_o antipater_n and_o cleophante_n the_o thyrd_o be_v refer_v to_o damocrates_n it_o do_v not_o appear_v by_o any_o thing_n write_v by_o galen_n which_o of_o these_o three_o composition_n be_v best_a to_o be_v follow_v and_o so_o of_o y_fw-fr e_o learned_a man_n of_o our_o time_n some_o have_v use_v the_o one_o and_o some_o the_o other_o many_o do_v best_o like_v of_o the_o first_o description_n attribute_v to_o andromachus_n both_o for_o that_o andromachus_n by_o the_o opinion_n of_o galen_n and_o of_o all_o other_o ancient_a writer_n be_v adjudge_v very_o skilful_a in_o compound_v of_o medicine_n &_o therein_o do_v far_o excel_v all_o physician_n of_o his_o time_n and_o also_o because_o it_o may_v be_v just_o gather_v that_o that_o description_n be_v the_o very_a same_o which_o mithridates_n use_v for_o in_o y_z e_o andromachus_n be_v physician_n to_o nero_n the_o emperor_n of_o rome_n it_o appear_v that_o he_o obtain_v to_o see_v and_o to_o consider_v of_o all_o the_o book_n which_o find_v in_o mithridates_n closet_n be_v translate_v into_o latin_a by_o lineus_fw-la the_o grammarian_n and_o bring_v to_o rome_n and_o it_o be_v not_o agreeable_a to_o reason_n that_o andromachus_n study_v to_o make_v a_o more_o perfect_a medicine_n then_o that_o which_o come_v under_o the_o name_n of_o mithridatium_n will_v also_o invent_v a_o other_o under_o the_o same_o name_n but_o it_o be_v very_o probable_a that_o andromachus_n with_o diligence_n peruse_v the_o recept_n of_o mithridatium_n use_v of_o mithridates_n will_v leave_v it_o in_o such_o form_n as_o mithridates_n compound_v it_o and_o devise_v a_o other_o by_o the_o same_o which_o he_o mean_v to_o make_v more_o perfect_a andromachus_n therefore_o not_o alter_v the_o description_n of_o mithridatium_n but_o leave_v it_o in_o the_o same_o form_n as_o it_o be_v find_v confect_v a_o other_o which_o he_o call_v theriaca_n and_o where_o we_o do_v read_v in_o y_z e_o 2._o de_fw-la antid_v of_o galen_n a_o other_o recept_n set_v down_o under_o the_o name_n of_o theriaca_n mithridatis_n with_o assertion_n that_o the_o king_n use_v the_o same_o yet_o it_o seem_v not_o to_o be_v y_z t_o mithridatium_n which_o be_v find_v in_o the_o closet_n of_o that_o king_n for_o all_o writer_n do_v confess_v that_o andromachus_n long_v after_o add_v to_o that_o recept_n of_o mithridates_n the_o flesh_n of_o viper_n so_o that_o mithridatium_n compound_v by_o mithridates_n have_v not_o in_o it_o the_o flesh_n of_o viper_n and_o that_o theriacle_n which_o galen_n in_o that_o place_n call_v theriaca_n mithridatis_n do_v receive_v the_o flesh_n of_o viper_n so_o it_o follow_v that_o it_o be_v not_o the_o mithridatium_n use_v of_o mithridates_n and_o he_o that_o will_v with_o diligence_n peruse_v that_o recept_n mention_v of_o galen_n by_o the_o name_n of_o theriaca_n mithridatis_n shalâ—_n find_v it_o in_o y_z e_z simples_n not_o much_o differ_v from_o theriaca_n andromachi_n and_o many_o thing_n repeat_v twice_o in_o diverse_a clause_n do_v argue_v a_o imperfection_n that_o galen_n may_v be_v think_v in_o y_z t_z place_n to_o speak_v after_o y_z e_z common_a opinion_n when_o he_o affirm_v it_o to_o be_v the_o same_o which_o mithridates_n use_v be_v in_o deed_n far_o different_a from_o that_o medicine_n wherefore_o we_o may_v reasonable_o conclude_v that_o the_o first_o recept_n transcribe_v by_o galen_n in_o 2._o de_fw-la antid_v out_o of_o andromachus_n work_v be_v in_o truth_n the_o self_n same_o that_o mithridates_n use_v and_o in_o my_o opinion_n in_o that_o respect_n the_o better_a to_o be_v like_v and_o the_o rather_o to_o be_v follow_v for_o what_o better_a assurance_n can_v we_o have_v of_o the_o true_a and_o perfect_a confection_n of_o this_o medicine_n then_o that_o which_o be_v deliver_v by_o mithridates_n and_o what_o description_n can_v more_o assure_v we_o of_o the_o effect_n of_o this_o medicine_n then_o y_z t_z composition_n which_o mithridates_n follow_v who_o first_o give_v so_o notable_a proof_n of_o the_o medicine_n and_o thereby_o the_o first_o credit_n to_o the_o same_o so_o that_o if_o by_o discourse_n of_o reason_n it_o may_v be_v prove_v that_o a_o other_o description_n be_v more_o artificial_a and_o more_o agreeable_a to_o the_o rule_n of_o confection_n of_o medicine_n yet_o in_o my_o opinion_n this_o description_n be_v the_o same_o that_o mithridates_n use_v set_v down_o happy_o by_o the_o king_n more_o according_a to_o experience_n then_o art_n be_v rather_o to_o be_v follow_v then_o any_o other_o think_v more_o cunning_o address_v nevertheless_o it_o be_v not_o to_o be_v deem_v that_o king_n mithridates_n be_v altogether_o unskylfull_a when_o many_o volume_n concern_v physic_n be_v find_v in_o his_o closet_n &_o translate_v into_o latin_a bring_v to_o rome_n and_o it_o appear_v that_o he_o take_v delight_n in_o medicinal_a matter_n have_v about_o he_o dyverse_a physician_n who_o may_v artificial_o dispense_v the_o simples_n in_o mithridatium_n and_o galen_n in_o the_o say_a book_n de_fw-fr antid_v commend_v the_o description_n of_o mithridatium_n attribute_v to_o andromachus_n whereby_o it_o appear_v that_o this_o description_n of_o mithridatium_n be_v not_o address_v altogether_o without_o art_n for_o which_o cause_n y_fw-es e_fw-it learn_v of_o our_o time_n have_v great_a reason_n to_o prefer_v that_o description_n of_o mithridatium_n before_o other_o albeit_o some_o do_v more_o esteem_v the_o composition_n of_o damocrates_n as_o with_o more_o art_n and_o more_o cunning_a dispense_v notwithstanding_o because_o it_o be_v very_o likely_a y_fw-mi t_o the_o precept_n attribute_v to_o andromachus_n as_o find_v in_o his_o book_n be_v the_o self_n same_o that_o mithridates_n use_v and_o have_v of_o many_o in_o this_o our_o country_n of_o late_a year_n be_v follow_v i_o think_v best_a in_o this_o place_n to_o express_v y_z e_o same_o as_o i_o do_v find_v it_o in_o galen_n in_o 2._o de_fw-la antid_v and_o be_v in_o many_o antidotary_n book_n allow_v which_o be_v as_o follow_v rec._n glicirrizae_fw-la Ê’_n seven_o ob_fw-la iiij_o spicae_fw-la nardi_fw-la Ê’_n seven_o ob_fw-la iij._n croci_fw-la cinnamomi_fw-la zinziberis_fw-la ana_fw-la Ê’_n seven_o ob_fw-la ij_o galbani_fw-la Ê’_n seven_o castorei_fw-la costi_fw-la ana_fw-la Ê’_n vj._n ob_fw-la ij_o scordij_fw-la iunci_fw-la odorati_fw-la
for_o then_o in_o deed_n every_o simple_a retain_v his_o own_o virtue_n opium_n may_v remit_v the_o hot_a quality_n of_o the_o rest_n at_o what_o time_n neither_o of_o these_o medicine_n be_v general_o to_o be_v use_v but_o for_o some_o special_a point_n as_o galen_n to_o provoke_v sleep_n do_v counsel_n new_a theriacle_n but_o after_o fermentation_n be_v perfect_v all_o the_o simples_n one_o alter_v the_o other_o every_o one_o have_v quality_n so_o break_v that_o not_o one_o retain_v his_o own_o nature_n then_o sure_o the_o common_a form_n result_v do_v follow_v the_o simples_n which_o do_v bear_v dominion_n and_o they_o in_o both_o these_o medicine_n be_v hot_a and_o dry_a and_o y_z e_z hot_a and_o dry_a simples_n in_o theriacle_n be_v more_o in_o number_n and_o of_o great_a force_n then_o in_o mithridalium_n as_o may_v appear_v to_o he_o that_o will_v compare_v both_o confection_n whereby_o it_o follow_v that_o the_o common_a quality_n arise_v in_o theriacle_n do_v heat_n more_o than_o that_o in_o mithridatium_n neither_o the_o increase_n of_o opium_n do_v in_o proportion_n answer_v the_o strength_n of_o heat_n in_o it_o neither_o have_v it_o any_o such_o force_n so_o great_o to_o contemper_v the_o simples_n as_o these_o man_n do_v imagine_v for_o although_o opium_n have_v special_a property_n above_o other_o medicine_n to_o induce_v sleep_n yet_o his_o cool_a quality_n of_o many_o writer_n be_v not_o account_v so_o great_a for_o it_o have_v so_o strong_a bitterness_n that_o many_o do_v suppose_v that_o it_o have_v a_o mixed_a nature_n consist_v of_o many_o hot_a part_n if_o it_o be_v true_a that_o galen_n write_v in_o his_o 5._o book_n of_o simples_n that_o all_o bitter_a thing_n be_v hot_a and_o be_v certain_a y_fw-mi t_o opium_n do_v stupefy_v &_o strong_o cause_v sleep_n it_o be_v of_o some_o infer_v y_o it_o that_o power_n do_v rather_o proceed_v of_o a_o property_n of_o substance_n than_o altogether_o depend_v of_o his_o cool_a quality_n wherefore_o it_o be_v not_o without_o reason_n affirm_v by_o learned_a man_n write_v hereof_o that_o mithridatium_n do_v not_o so_o strong_o heat_n as_o theriacle_n and_o experience_n do_v also_o confirm_v the_o same_o for_o who_o so_o use_v these_o medicine_n doubtless_o he_o shall_v find_v that_o theriacle_n right_o compound_v after_o andromachus_n description_n which_o be_v in_o all_o this_o treatise_n to_o be_v understand_v and_o be_v in_o these_o day_n of_o the_o apothecary_n most_o common_o make_v and_o so_o of_o the_o wise_a sort_n in_o most_o vulgar_a use_n do_v heat_n more_o than_o mithridatium_n which_o be_v confess_v of_o the_o writer_n comment_v upon_o the_o antidotary_n of_o nicolaus_n and_o in_o this_o our_o age_n of_o many_o learned_a man_n affirm_v for_o which_o cause_n many_o in_o these_o day_n without_o danger_n do_v use_n mithridatium_n when_o need_n require_v in_o summer_n time_n &_o hot_a season_n very_o few_o and_o seldom_o theriacle_n and_o galen_n do_v express_o forbid_v to_o gieve_v theriacle_n to_o child_n more_o safe_a therefore_o be_v the_o use_n of_o mithridatium_n then_o of_o theriacle_n not_o only_o in_o respect_n of_o the_o heat_a quality_n which_o seem_v less_o &_o more_o gentle_a in_o mithridatium_n but_o also_o in_o respect_n that_o a_o great_a quantity_n of_o opium_n be_v in_o theriacle_n for_o admit_v that_o opium_n by_o fermentation_n sustain_v great_a alteration_n notwithstanding_o y_o e_o common_a form_n of_o theriacle_n take_v some_o infection_n of_o opium_n y_fw-fr t_o some_o effect_n decline_v to_o his_o nature_n do_v also_o proceed_v and_o the_o more_o if_o that_o stupify_a and_o dormitory_n power_n in_o opium_n do_v depend_v rather_o of_o property_n of_o substance_n they_o of_o manifest_a cool_a quality_n as_o some_o do_v argue_v for_o the_o property_n of_o substance_n in_o medicine_n have_v not_o like_a alteration_n by_o fermentation_n as_o the_o manifest_a quality_n have_v by_o reaction_n we_o may_v therefore_o fear_v the_o common_a and_o often_o use_v of_o theriacle_n for_o y_o e_o quantity_n of_o opium_n in_o it_o for_o like_o reason_n often_o use_v of_o theriacle_n may_v be_v suspect_v because_o of_o the_o flesh_n of_o viper_n add_v to_o it_o as_o the_o base_a &_o ground_n of_o the_o medicine_n for_o notwithstanding_o y_fw-mi e_o great_a care_n of_o the_o place_n of_o the_o time_n of_o the_o kind_n observe_v in_o take_v and_o choose_v of_o the_o viper_n the_o diligence_n in_o prepare_v the_o care_n of_o mixture_n with_o other_o thing_n for_o the_o better_a correction_n of_o the_o malignity_n of_o y_fw-fr e_o beast_n which_o haply_o may_v remain_v in_o the_o flesh_n yet_o a_o man_n may_v doubt_v of_o some_o error_n commit_v in_o so_o dangerous_a a_o case_n and_o though_o all_o thing_n therein_o be_v ryghte_o do_v yet_o some_o little_a quality_n of_o the_o nature_n of_o y_fw-fr e_o beast_n will_v remain_v that_o a_o man_n may_v suspect_v often_o to_o use_v the_o medicine_n and_o where_o king_n mithridates_n be_v expert_a in_o physical_a matter_n it_o be_v not_o to_o be_v adjudge_v but_o that_o he_o do_v aswell_o know_v the_o nature_n of_o the_o flesh_n of_o viper_n as_o he_o know_v the_o venom_n of_o the_o beast_n so_o it_o be_v very_o likely_a that_o he_o purpose_v to_o compound_v a_o medicine_n to_o be_v often_o take_v for_o his_o safety_n against_o poison_n do_v of_o purpose_n make_v it_o without_o the_o flesh_n of_o viper_n know_v that_o if_o he_o shall_v have_v add_v that_o he_o may_v not_o with_o like_a safety_n have_v daily_o use_v y_o e_o same_o and_o what_o learned_a man_n do_v so_o often_o in_o these_o day_n counsel_n theriacle_n as_o do_v mithridatium_n and_o we_o do_v in_o this_o our_o time_n with_o less_o danger_n and_o more_o security_n for_o the_o measles_n the_o small_a pock_n the_o worm_n and_o for_o internal_a disease_n in_o child_n geve_v mithridatium_n then_o theriacle_n we_o may_v therefore_o in_o my_o opinion_n just_o conclude_v that_o mithridatium_n be_v a_o medicine_n more_o general_o to_o be_v use_v &_o may_v often_o an_o with_o more_o safety_n be_v geaven_v then_o theriacle_n of_o the_o age_n and_o keep_n of_o mithridatium_n where_o we_o have_v sufficient_o declare_v that_o compound_a medicine_n must_v have_v a_o time_n of_o fermentation_n before_o they_o be_v bring_v to_o use_v this_o place_n require_v that_o we_o do_v declare_v the_o time_n when_o mithridatium_n be_v sufficient_o ferment_v and_o come_v to_o his_o perfection_n galen_n in_o his_o book_n de_fw-fr theriaca_fw-la do_v write_v exact_o of_o the_o time_n of_o fermentation_n of_o theriacle_n affirm_v that_o it_o be_v thorough_o concoct_v in_o twelve_o year_n not_o deny_v but_o y_o t_o it_o have_v concoction_n in_o short_a time_n as_o in_o 5._o and_o in_o 7._o year_n so_o that_o we_o be_v to_o judge_v that_o theriacle_n be_v not_o sufficient_o ripe_a to_o be_v use_v before_o five_o year_n and_o in_o 7_o year_n be_v better_o digest_v &_o in_o xij_o year_n have_v his_o full_a fermentation_n and_o perfect_a concoction_n yet_o aetius_n and_o paulus_n aegineta_n do_v measure_n the_o concoction_n of_o theriacle_n in_o short_a time_n for_o aetius_n say_v that_o theriacle_n be_v ferment_v in_o xij_o month_n and_o that_o it_o may_v be_v use_v after_o one_o month_n in_o some_o case_n and_o so_o affirm_v that_o it_o endure_v to_o thirty_o year_n where_o paulus_n appoint_v y_o e_o age_n of_o theriacle_n to_o be_v twenty_o year_n therein_o he_o do_v not_o great_o differ_v from_o aetius_n for_o he_o make_v the_o term_n of_o theriacle_n to_o be_v 30_o year_n do_v also_o say_v that_o then_o it_o be_v good_a in_o light_a disease_n so_o that_o by_o aetius_n theriacle_n may_v be_v use_v after_o xij_o month_n and_o continue_v in_o good_a perfection_n to_o 20._o year_n and_o after_o decline_v that_o at_o 30._o year_n it_o be_v age_v yet_o may_v it_o be_v use_v in_o disease_n which_o be_v not_o very_o great_a our_o late_a writer_n do_v general_o better_o allow_v of_o aetius_n &_o paulus_n opinion_n for_o the_o age_n of_o theriacle_n then_o of_o galens_n and_o some_o suppose_v a_o error_n or_o fault_n in_o y_z t_z place_n in_o galen_n and_o so_o they_o do_v affirm_v y_z t_o theriacle_n be_v full_o concoct_v in_o the_o space_n of_o xij_o month_n and_o then_o may_v be_v sell_v of_o the_o apothecary_n and_o that_o the_o same_o be_v well_o keep_v will_v continue_v in_o good_a strength_n 20._o year_n and_o after_o do_v decline_v and_o wax_v weak_a and_o yet_o may_v be_v use_v when_o it_o be_v 30._o year_n old_a but_o it_o be_v then_o as_o a_o old_a man_n decay_v and_o weak_a of_o strength_n of_o mithridatium_n the_o former_a writer_n have_v set_v down_o no_o time_n of_o concoction_n leave_v to_o a_o wise_a man_n to_o determine_v of_o y_fw-fr t_o which_o be_v write_v according_o of_o theriacle_n