satisfy_v in_o a_o few_o point_n the_o grand_a argument_n on_o which_o you_o build_v your_o hypothesis_n be_v take_v from_o the_o green_a colour_n of_o the_o serum_fw-la which_o arise_v from_o its_o mixture_n with_o syrup_n of_o violet_n it_o must_v be_v confess_v that_o alkalies_n usual_o give_v it_o this_o tincture_n and_o there_o may_v be_v something_o of_o a_o alkaly_n or_o at_o least_o analagous_n to_o it_o in_o the_o serum_fw-la but_o notwithstanding_o this_o the_o many_o inference_n which_o you_o be_v please_v to_o draw_v from_o this_o phaenomenon_n in_o my_o opinion_n will_v hardly_o hold_v good_a for_o 1._o if_o this_o alkalizated_a serum_fw-la be_v the_o original_a of_o distemper_n than_o it_o must_v follow_v that_o wheresoever_o we_o find_v this_o serum_fw-la there_o must_v be_v likewise_o a_o distemper_n now_o i_o appeal_v to_o yourself_o if_o the_o blood_n of_o a_o healthy_a person_n will_v not_o give_v syrup_n of_o violet_n a_o green_a tincture_n do_v not_o then_o the_o 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how_o come_v it_o to_o pass_v that_o on_o the_o dissolution_n of_o the_o texture_n of_o the_o blood_n they_o claim_v the_o high_a place_n and_o nothing_o will_v serve_v their_o turn_n but_o they_o must_v needs_o swim_v in_o the_o serum_fw-la if_o volatile_a how_o be_v it_o that_o we_o many_o time_n find_v this_o warm_a serum_fw-la to_o be_v little_o better_a than_o insipid_a volatile_a salt_n you_o know_v be_v aculeat_v and_o affect_v the_o palate_n strong_o may_v they_o not_o rather_o be_v of_o a_o sulphureous_a nature_n since_o it_o be_v the_o nature_n of_o such_o substance_n to_o sit_v uppermost_a on_o the_o dissolution_n of_o body_n but_o three_o if_o alkaly_n be_v the_o original_a of_o all_o distemper_n whence_o be_v it_o that_o in_o dropsy_n catarrh_n some_o gout_n and_o other_o distemper_n we_o find_v the_o texture_n of_o the_o blood_n so_o thin_a it_o be_v observable_a that_o those_o particle_n you_o term_v alkaly_n the_o more_o the_o blood_n be_v saturate_v with_o they_o of_o the_o more_o thick_a consistence_n it_o be_v as_o we_o see_v in_o pleurisy_n rheumatism_n and_o other_o inflammatory_n case_n in_o which_o distemper_n if_o in_o any_o these_o alkaly_n abound_v be_v not_o then_o its_o tenuity_n rather_o to_o be_v impute_v to_o acid_n do_v not_o acid_n immediate_o put_v the_o blood_n in_o a_o fusion_n and_o render_v it_o thin_a beside_o if_o alkaly_n do_v always_o offend_v and_o cause_v pain_n it_o must_v follow_v that_o acid_n must_v give_v ease_n but_o i_o assure_v you_o i_o have_v often_o experience_v the_o contrary_a for_o upon_o the_o exhibition_n of_o rhenish_n white-wine_n and_o other_o acid_n i_o have_v find_v the_o pain_n immediate_o exasperate_v and_o many_o time_n it_o have_v be_v a_o long_a while_n ere_o they_o go_v off_o again_o if_o the_o gout_n proceed_v from_o a_o alkaly_n what_o be_v the_o reason_n you_o use_v so_o much_o sassafras_n in_o its_o cure_n be_v sassafras_n a_o acid_n and_o so_o proper_a to_o subdue_v this_o alkaly_n i_o 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i_o as_o to_o these_o i_o shall_v be_v glad_a to_o close_v with_o your_o opinion_n and_o embrace_v any_o thing_n that_o be_v new_a for_o i_o believe_v medicine_n though_o it_o have_v meet_v with_o great_a improvement_n of_o late_a to_o be_v capable_a of_o far_o great_a i_o will_v give_v you_o no_o far_o trouble_v only_o after_o thanks_o to_o you_o for_o your_o indefatigable_a labour_n in_o search_v out_o the_o truth_n of_o thing_n subscribe_v your_o humble_a servant_n f._n tuthill_n the_o doctrine_n of_o acid_n in_o the_o cure_n of_o disease_n far_o assert_v etc._n etc._n worthy_a sir_n i_o have_v read_v your_o letter_n with_o all_o the_o pleasure_n and_o satisfaction_n imaginable_a the_o objection_n you_o have_v raise_v against_o my_o hypothesis_n be_v the_o most_o solid_a and_o substantial_a i_o have_v ever_o yet_o meet_v with_o and_o you_o may_v assure_v yourself_o that_o i_o have_v so_o great_a a_o value_n and_o esteem_n for_o truth_n that_o i_o will_v not_o dare_v to_o contend_v for_o any_o thing_n which_o be_v the_o product_n of_o my_o shallow_a understanding_n that_o in_o the_o least_o stand_v in_o opposition_n to_o it_o but_o as_o i_o will_v not_o by_o any_o mean_n in_o the_o world_n oppose_v truth_n so_o at_o the_o same_o time_n i_o will_v not_o be_v guilty_a of_o so_o much_o cowardice_n as_o to_o quit_v its_o interest_n because_o i_o meet_v with_o a_o multitude_n of_o opposer_n although_o your_o objection_n do_v carry_v the_o fair_a show_v along_o with_o they_o of_o any_o thing_n i_o have_v meet_v with_o of_o this_o kind_n yet_o i_o do_v it_o at_o all_o doubt_n but_o very_o easy_o to_o clear_v myself_o from_o they_o the_o which_o i_o shall_v endeavour_v to_o do_v with_o as_o much_o candour_n and_o friendship_n as_o you_o propose_v they_o letter_n i_o have_v peruse_v your_o ingenious_a treatise_n of_o the_o gout_n in_o which_o you_o seem_v to_o accuse_v alkaly_n as_o the_o original_a of_o all_o distemper_n before_o i_o subscribe_v to_o this_o opinion_n i_o 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not_o suppose_v but_o that_o i_o shall_v great_o displease_v by_o disturb_v they_o in_o the_o quiet_a possession_n of_o a_o opinion_n that_o have_v long_o be_v embrace_v by_o all_o sort_n of_o people_n i_o my_o self_n as_o i_o elsewhere_o acknowledge_v be_v former_o as_o great_a a_o stickler_n for_o the_o use_v of_o alkaly_n in_o the_o cure_n of_o disease_n and_o do_v as_o little_o believe_v that_o they_o be_v the_o cause_n of_o they_o as_o any_o one_o of_o my_o hot_a opposer_n now_o do_v the_o method_n by_o which_o i_o come_v to_o change_v my_o sentiment_n i_o shall_v here_o faithful_o relate_v to_o you_o whilst_o i_o be_v fair_o jog_v on_o in_o the_o ordinary_a method_n of_o practice_n a_o certain_a gentleman_n recommend_v to_o i_o a_o powerful_a acid_n which_o he_o tell_v i_o i_o may_v rely_v upon_o
etc._n but_o my_o hypothesis_n do_v not_o altogether_o hang_v upon_o so_o slender_a a_o thread_n as_o the_o change_n of_o colour_n though_o that_o be_v a_o better_a foundation_n than_o a_o great_a many_o hypothesis_n be_v build_v upon_o you_o may_v very_o well_o remember_v that_o i_o bring_v this_o experiment_n upon_o the_o stage_n only_o to_o satisfy_v gentleman_n who_o have_v not_o the_o conveniency_n of_o make_v more_o elaborate_a one_o and_o all_o mankind_n have_v imbibe_v the_o notion_n that_o if_o any_o thing_n ail_v they_o they_o immediate_o conclude_v that_o it_o proceed_v from_o a_o acidity_n of_o their_o blood_n i_o therefore_o think_v it_o my_o duty_n to_o convince_v they_o of_o the_o contrary_a in_o the_o most_o familiar_a manner_n i_o can_v but_o i_o never_o expect_v that_o physician_n shall_v take_v up_o with_o it_o i_o refer_v they_o to_o a_o more_o certain_a method_n viz._n to_o analize_v the_o blood_n of_o their_o sick_a patient_n and_o to_o compare_v the_o substance_n 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as_o to_o the_o cause_n of_o disease_n i_o do_v see_v how_o we_o can_v ready_o find_v out_o proper_a medicine_n letter_n for_o first_o if_o this_o alkalisated_a serum_fw-la be_v the_o original_a of_o distemper_n than_o it_o must_v follow_v that_o wheresoever_o we_o find_v this_o serum_fw-la there_o must_v be_v likewise_o a_o distemper_n now_o i_o appeal_v to_o yourself_o if_o the_o blood_n of_o a_o healthy_a person_n will_v not_o give_v syrup_n of_o violet_n a_o green_a tincture_n do_v not_o then_o the_o argument_n labour_n may_v we_o not_o then_o impute_v this_o phaenomenon_n to_o arise_v rather_o from_o a_o due_a mixture_n of_o the_o principle_n than_o from_o any_o vitiate_a habit_n of_o blood_n answer_n i_o confess_v this_o be_v close_o argue_v and_o much_o to_o the_o purpose_n but_o you_o may_v remember_v that_o i_o no_o where_n say_v that_o the_o serum_fw-la of_o well_o person_n blood_n will_v not_o turn_v a_o solution_n of_o syrup_n of_o violet_n from_o a_o blue_a colour_n to_o that_o of_o greenness_n but_o on_o the_o other_o hand_n i_o have_v assert_v that_o the_o blood_n of_o those_o labour_a under_o any_o distemper_n i_o have_v meet_v with_o will_v do_v it_o in_o order_n to_o prove_v that_o the_o say_v distemper_n do_v not_o proceed_v from_o acid_n because_o if_o it_o have_v abound_v with_o acid_n instead_o of_o turn_v it_o from_o blue_a to_o green_a it_o will_v as_o be_v before_o observe_v have_v turn_v it_o from_o blue_a to_o red_a well_o but_o still_o the_o serum_fw-la of_o the_o blood_n of_o a_o well_o person_n will_v cause_v the_o same_o change_n in_o the_o solution_n of_o syrup_n of_o violet_n as_o that_o of_o a_o sick_a one_o and_o therefore_o to_o rid_v myself_o of_o that_o difficulty_n be_v the_o great_a thing_n i_o have_v now_o to_o do_v first_o i_o all_o along_o throughout_o my_o tract_n of_o the_o gout_n the_o piece_n you_o refer_v to_o and_o elsewhere_o do_v endeavour_n to_o prove_v that_o the_o blood_n of_o person_n in_o a_o morbid_v state_n do_v more_o abound_v with_o alkalious_a particle_n than_o that_o of_o well_o person_n but_o no_o where_n say_v that_o the_o blood_n of_o well_o person_n have_v no_o alkaly_a in_o it_o and_o that_o the_o blood_n of_o sick_a people_n in_o all_o or_o most_o distemper_n do_v abound_v with_o such_o particle_n more_o than_o that_o of_o those_o that_o be_v in_o a_o state_n of_o health_n be_v to_o be_v demonstrate_v several_a way_n first_o if_o you_o take_v a_o equal_a proportion_n of_o the_o serum_fw-la of_o the_o blood_n of_o a_o healthy_a person_n and_o of_o that_o of_o a_o person_n in_o a_o fever_n pleurisy_n etc._n etc._n and_o pour_v they_o into_o the_o same_o quantity_n of_o solution_n of_o syrup_n of_o violet_n of_o equal_a strength_n you_o will_v find_v that_o wherein_o the_o serum_fw-la of_o the_o sick_a person_n be_v blood_n be_v pour_v to_o be_v much_o green_a than_o the_o other_o second_o if_o you_o take_v two_o ounce_n of_o the_o blood_n of_o a_o healthy_a person_n as_o it_o come_v out_o of_o the_o vein_n serum_fw-la and_o all_o together_o and_o two_o ounce_n of_o the_o blood_n of_o a_o person_n in_o a_o fever_n pleurisy_n a_o fit_a of_o the_o gout_n etc._n etc._n and_o commit_v they_o to_o distillation_n in_o the_o same_o degree_n of_o heat_n you_o will_v find_v that_o the_o blood_n of_o the_o sick_a person_n will_v produce_v a_o much_o great_a quantity_n of_o alkaly_n than_o that_o of_o the_o person_n in_o a_o state_n of_o health_n second_o what_o shall_v i_o do_v with_o this_o alkaly_n that_o be_v to_o be_v find_v in_o the_o blood_n of_o healthy_a person_n because_o every_o body_n have_v some_o alkaly_n in_o their_o blood_n must_v every_o body_n therefore_o labour_v under_o some_o distemper_n why_o true_o i_o can_v say_v that_o i_o ever_o yet_o meet_v with_o that_o person_n who_o upon_o strict_a enquiry_n have_v not_o some_o complaint_n or_o other_o to_o make_v mankind_n since_o the_o fall_n be_v subject_a to_o death_n every_o moment_n there_o be_v since_o that_o time_n a_o principle_n of_o death_n in_o opposition_n to_o that_o of_o life_n implant_v in_o our_o nature_n and_o not_o only_o in_o our_o nature_n but_o in_o the_o nature_n of_o every_o thing_n else_o for_o our_o sake_n and_o god_n say_v to_o adam_n upon_o his_o fall_n curse_v be_v the_o ground_n for_o thy_o sake_n etc._n etc._n i_o confess_v there_o be_v many_o in_o our_o age_n who_o will_v laugh_v at_o and_o ridicule_n i_o for_o have_v recourse_n to_o sacred_a writ_n especial_o to_o the_o write_n of_o moses_n which_o they_o look_v upon_o as_o a_o kind_n of_o romance_n but_o let_v they_o laugh_v on_o if_o there_o be_v not_o a_o principle_n of_o death_n within_o we_o how_o be_v it_o possible_a for_o a_o man_n one_o hour_n to_o be_v in_o a_o good_a state_n of_o health_n and_o the_o very_a next_o to_o be_v expire_a how_o this_o may_v be_v i_o shall_v endeavour_v to_o demonstrate_v as_o clear_o as_o possible_o i_o can_v all_o the_o alkaly_n that_o there_o be_v to_o be_v find_v in_o the_o blood_n be_v most_o certain_o a_o excrement_n and_o in_o a_o way_n of_o be_v carry_v off_o by_o some_o of_o the_o emunctory_n and_o if_o any_o of_o the_o emunctory_n chance_v to_o be_v stop_v that_o this_o excrementitious_a alkaly_n have_v not_o room_n to_o pass_v out_o by_o they_o why_o then_o there_o be_v a_o distemper_n of_o some_o kind_n or_o other_o cause_v the_o blood_n be_v overcharge_v with_o this_o excrementitious_a matter_n how_o many_o distemper_n be_v occasion_v by_o what_o we_o call_v take_v of_o cold_a which_o be_v nothing_o else_o but_o a_o constipation_n of_o the_o pore_n what_o be_v the_o occasion_n of_o the_o jaundice_n but_o a_o obstruction_n of_o those_o vessel_n in_o the_o liver_n which_o separate_v the_o bilious_a particle_n from_o the_o blood_n and_o what_o dreadful_a distemper_n do_v the_o jaundice_n frequent_o cause_n how_o be_v mortal_n torment_v by_o the_o stone_n in_o the_o kidney_n and_o bladder_n and_o what_o be_v the_o original_a cause_n of_o they_o but_o a_o obstruction_n in_o the_o kidney_n whereby_o the_o excrementitious_a alkaly_n which_o shall_v be_v carry_v off_o that_o way_n by_z its_z over_o long_o stay_v in_o those_o part_n be_v convert_v into_o that_o substance_n we_o call_v a_o stone_n and_o whoever_o will_v give_v themselves_o the_o trouble_n of_o distil_a stone_n either_o from_o the_o kidney_n or_o bladder_n will_v find_v that_o they_o be_v compose_v of_o alkalious_a particle_n i_o can_v expatiate_v and_o i_o doubt_v not_o give_v a_o account_n of_o the_o cause_n of_o all_o or_o most_o of_o the_o distemper_n attend_v human_a body_n from_o the_o excrementitious_a alkaly_n be_v hinder_v from_o be_v carry_v off_o by_o the_o proper_a emunctory_n and_o i_o appeal_v to_o all_o
be_v observable_a that_o those_o particle_n you_o term_v alkaly_n the_o more_o the_o blood_n be_v saturate_v with_o they_o the_o more_o thick_a consistence_n it_o be_v of_o as_o we_o see_v in_o pleurisy_n rheumatism_n and_o other_o inflammatory_n case_n in_o which_o distemper_n if_o in_o any_o these_o alkaly_n abound_v be_v not_o then_o its_o tenuity_n rather_o to_o be_v impute_v to_o acid_n do_v not_o acid_n immediate_o put_v the_o blood_n in_o a_o fusion_n and_o render_v it_o thin_a answ_n in_o most_o inflammatory_n case_n where_o the_o blood_n be_v immediate_o affect_v there_o the_o serum_fw-la be_v viscous_a and_o sizy_n be_v overcharge_v with_o alkalious_a particle_n but_o in_o those_o case_n you_o mention_v and_o in_o some_o other_o where_o the_o blood_n be_v over_o thin_a it_o be_v not_o the_o over_o thinness_n of_o the_o blood_n which_o be_v the_o only_a cause_n of_o those_o disease_n but_o a_o destruction_n of_o the_o tone_n of_o the_o part_n and_o where_o the_o tone_n of_o 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