best_a part_n of_o opium_n which_o be_v so_o much_o the_o better_a the_o more_o it_o abound_v with_o they_o 9_o if_o it_o yield_v any_o other_o tincture_n than_o red_a it_o be_v not_o right_a and_o the_o dull_a or_o pale_a the_o red_a be_v the_o worse_a or_o weak_a it_o be_v 10._o the_o best_a be_v heavy_a in_o proportion_n to_o its_o bulk_n which_o you_o may_v soon_o experiment_n thus_o weigh_v a_o ounce_n of_o each_o in_o the_o air_n then_o weigh_v they_o just_a as_o they_o be_v in_o the_o brass_n scales_n in_o water_n and_o the_o heavy_a will_n outweigh_v the_o other_o in_o water_n for_o the_o heavy_a any_o thing_n be_v the_o less_o water_n take_v from_o its_o weight_n in_o proportion_n to_o its_o bulk_n this_o be_v a_o infallible_a and_o most_o ready_a way_n to_o know_v the_o weight_n of_o any_o thing_n in_o proportion_n to_o its_o bulk_n note_v that_o my_o discourse_n be_v most_o particular_o concern_v the_o best_a sort_n of_o crude_a turkey_n opium_n that_o be_v the_o best_a that_o we_o have_v in_o common_a use_n and_o that_o its_o effect_n and_o not_o those_o of_o any_o preparation_n thereof_o be_v set_v down_o in_o the_o follow_a chapter_n chap_n iii_o the_o effect_n of_o opium_n use_v external_o opium_n use_v external_o have_v two_o sort_n of_o effect_n upon_o a_o humane_a body_n 1._o as_o a_o opiate_n to_o cause_n sleep_n take_v away_o pain_n etc._n etc._n 2._o as_o a_o alterative_a of_o the_o part_n it_o be_v apply_v to_o i._o as_o a_o opiate_n it_o be_v of_o very_o uncertain_a and_o uneven_a effect_n when_o apply_v external_o for_o sometime_o it_o cause_v sleep_n take_v away_o pain_n but_o it_o often_o fail_v therefore_o it_o be_v general_o much_o better_a safe_a more_o certain_a and_o effectual_a to_o use_v it_o internal_o i_o do_v scarce_o know_v the_o case_n wherein_o it_o be_v better_a to_o use_v it_o external_o than_o internal_o unless_o it_o be_v to_o smell_v to_o in_o some_o case_n but_o of_o these_o thing_n more_o particular_o when_o we_o come_v to_o the_o use_v of_o opium_n in_o cure_v prevent_v or_o paliate_a disease_n for_o here_o we_o only_o lie_v down_o effect_n in_o order_n to_o a_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n to_o which_o its_o internal_a effect_n will_v main_o contribute_v however_o it_o may_v be_v very_o useful_a to_o that_o end_n to_o lay_v down_o its_o alterative_a effect_n for_o thereby_o we_o shall_v in_o good_a measure_n know_v the_o prin_fw-mi ciple_n by_o which_o it_o operate_v ii_o it_o be_v external_a effect_n as_o a_o alterative_a be_v these_o viz._n 1._o it_o incides_fw-la resolve_n and_o discuss_n 2._o it_o relax_n and_o mollify_v 3._o it_o maturate_v and_o suppurate_v 4._o it_o exulcerate_v or_o cause_n blister_n if_o it_o be_v very_o strong_a and_o apply_v to_o person_n of_o a_o fine_a texture_n where_o the_o skin_n be_v tender_a but_o this_o effect_n belong_v more_o proper_o to_o the_o maslack_n or_o true_a 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o drop_n from_o the_o incision_n make_v in_o the_o head_n of_o the_o poppy_n especial_o the_o theban_a which_o afford_v a_o very_a powerful_a juice_n hence_o you_o may_v observe_v that_o the_o more_o it_o exulcerates_n or_o blister_n the_o better_a be_v the_o opium_n &_o vice_fw-la versâ_fw-la 5._o it_o be_v a_o psilotherick_n for_o it_o prevent_v hair_n to_o grow_v and_o cause_v the_o shed_v thereof_o 6._o it_o be_v hurtful_a to_o the_o eye_n and_o ear_n 7._o it_o excite_v itch_n apply_v in_o a_o moderate_a manner_n to_o the_o skin_n 8._o it_o excite_v venery_n apply_v to_o the_o perinaeum_n chap._n iu._n the_o effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o the_o moderate_a do_v in_o ordinary_a use_n to_o produce_v the_o follow_a effect_n be_v from_o one_o to_o three_o grain_n more_o or_o less_o according_a to_o the_o circumstance_n condition_n case_n constitution_n age_n &c_n &c_n of_o the_o person_n who_o take_v it_o 2._o it_o operate_v general_o in_o a_o short_a time_n after_o it_o be_v in_o the_o stomach_n that_o be_v in_o about_o half_a a_o hour_n more_o or_o less_o if_o take_v in_o a_o liquid_a form_n and_o in_o about_o a_o hour_n more_o or_o less_o if_o in_o a_o solid_a form_n drink_v a_o draught_n of_o water_n or_o some_o liquor_n after_o it_o otherwise_o it_o may_v be_v sometime_o near_o a_o hour_n and_o a_o half_a before_o it_o have_v its_o full_a effect_n but_o the_o time_n of_o its_o operation_n have_v a_o considerable_a latitude_n according_a to_o the_o disposition_n of_o the_o stomach_n and_o other_o circumstance_n as_o the_o vehicle_n it_o be_v take_v in_o etc._n etc._n the_o constant_a effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o diffuse_v itself_o in_o a_o kind_n of_o indefinite_a manner_n seizing_z one_o not_o unlike_o the_o gentle_a sweet_a deliquium_fw-la that_o we_o find_v upon_o our_o entrance_n into_o a_o most_o agreeable_a slumber_n which_o upon_o yield_v to_o it_o general_o end_v in_o sleep_n but_o if_o the_o person_n keep_v himself_o in_o action_n discourse_n or_o business_n it_o seem_v especial_o when_o give_v in_o a_o mornning_a after_o a_o moderate_a rest_n at_o night_n like_o a_o most_o delicious_a and_o extraordinary_a refreshment_n of_o the_o spirit_n upon_o very_o good_a news_n or_o any_o other_o great_a cause_n of_o joy_n as_o the_o sight_n of_o a_o dear_o belove_a person_n etc._n etc._n thought_n to_o have_v be_v lose_v at_o sea_n or_o the_o like_a cause_v such_o a_o pleasant_a ovation_n of_o the_o spirit_n serenity_n etc._n etc._n as_o we_o find_v after_o a_o competent_a measure_n of_o generous_a wine_n ad_fw-la hilaritatem_fw-la as_o man_n use_v to_o say_v it_o be_v indeed_o so_o unexpressible_o fine_a and_o sweet_a a_o pleasure_n that_o it_o be_v very_o difficult_a for_o i_o to_o describe_v or_o any_o to_o conceive_v it_o but_o such_o as_o actual_o feel_v it_o for_o it_o be_v as_o if_o a_o good_a genius_n possess_v or_o inform_v a_o man_n therefore_o people_n do_v common_o call_v it_o a_o heavenly_a condition_n as_o if_o no_o worldly_a pleasure_n be_v to_o be_v compare_v with_o it_o helmontianus_fw-la will_v doubtless_o express_v it_o by_o the_o archaeus_n in_o his_o very_a best_a humour_n it_o have_v be_v compare_v not_o without_o good_a cause_n to_o a_o permanent_a gentle_a degree_n of_o that_o pleasure_n which_o modesty_n forbid_v the_o name_n of_o and_o it_o be_v well_o worth_a a_o remark_n that_o both_o be_v pleasure_n of_o the_o same_o sense_n viz._n that_o of_o feel_v for_o it_o can_v be_v a_o pleasure_n of_o any_o other_o sense_n since_o it_o be_v internal_a 2._o it_o cause_v a_o brisk_a gay_a and_o good_a humour_n nor_o do_v i_o doubt_v but_o it_o have_v this_o effect_n upon_o sleep_a person_n as_o far_o as_o their_o condition_n be_v capable_a of_o observe_v it_o for_o you_o shall_v have_v they_o often_o tell_v of_o pleasant_a dream_n after_o it_o when_o they_o remember_v they_o and_o speak_v of_o any_o see_v bauchin_n and_o the_o author_n mention_v below_o under_o the_o four_o effect_n of_o opium_n 3._o it_o cause_v promptitude_n serenity_n alacrity_n and_o expediteness_n in_o dispatch_v and_o manage_n of_o business_n to_o which_o end_n and_o that_o of_o a_o good_a and_o gay_a humour_n which_o be_v near_o of_o kind_n it_o be_v common_o take_v in_o the_o morning_n in_o the_o eastern_a country_n with_o most_o certain_a effect_n the_o truth_n of_o which_o wedelius_n be_v force_v to_o confess_v though_o quite_o contrary_a to_o his_o hypothesis_n of_o opium_n fix_v and_o coagulate_v the_o spirit_n give_v a_o instance_n of_o a_o certain_a serene_a person_n who_o when_o she_o have_v any_o affair_n of_o great_a moment_n to_o dispatch_v do_v beforehand_o take_v opium_n with_o great_a advantage_n for_o she_o thereby_o find_v herself_o every_o way_n better_o dispose_v for_o business_n and_o more_o enable_v to_o bear_v the_o fatigue_n thereof_o which_o be_v the_o substance_n of_o what_o he_o write_v in_o latin_n many_o other_o author_n confirm_v the_o truth_n of_o these_o effect_n but_o above_o all_o the_o constant_a experience_n of_o the_o eastern_a nation_n put_v it_o out_o of_o all_o doubt_n 4._o it_o cause_v assurance_n ovation_n of_o the_o spirit_n courage_n contempt_n of_o danger_n and_o magnanimity_n much_o after_o the_o manner_n that_o generous_a wine_n do_v instead_o of_o which_o the_o turk_n etc._n etc._n use_v opium_n before_o engagement_n desperate_a attack_n etc._n etc._n as_o be_v most_o notorious_a to_o make_v they_o courageous_a which_o it_o certain_o do_v for_o your_o satisfaction_n as_o to_o this_o and_o other_o effect_n of_o opium_n not_o so_o common_o observe_v
why_o then_o do_v they_o write_v and_o trouble_v the_o world_n to_o peruse_v their_o book_n when_o they_o be_v so_o far_o from_o explain_v the_o property_n of_o opium_n that_o they_o scarce_o ever_o dare_v mention_v they_o nor_o set_v their_o hypothesise_n and_o they_o as_o much_o as_o in_o view_n of_o one_o another_o be_v not_o this_o a_o tacit_n confession_n of_o the_o incompetency_n of_o their_o supposition_n i_o beg_v pardon_n for_o call_v they_o they_o though_o they_o themselves_o do_v for_o i_o can_v offer_v they_o a_o great_a abuse_n than_o lay_v their_o spurious_a and_o lame_a brat_n at_o their_o door_n though_o one_o scarce_o need_v say_v any_o more_o of_o they_o yet_o lest_o i_o be_v think_v presumptuous_a or_o saucy_a for_o so_o much_o as_o offer_v to_o suspect_v the_o general_a foundation_n of_o all_o the_o famous_a author_n that_o ever_o live_v as_o galen_n avicenna_n etc._n etc._n among_o the_o ancient_n etmuller_n willis_n etc._n etc._n among_o the_o modern_n 1._o i_o will_v show_v you_o very_o just_a cause_n to_o suspect_v the_o insufficiency_n of_o the_o general_a foundation_n viz._n that_o opium_n diminish_v or_o disable_v the_o spirit_n 2._o i_o will_v prove_v that_o it_o do_v not_o do_v it_o by_o a_o cold_a quality_n 3._o that_o it_o do_v not_o do_v it_o by_o vapour_n fume_n aura_n or_o any_o such_o way_n 4._o that_o it_o diminish_v or_o disable_v the_o spirit_n by_o no_o mean_n whatsoever_o which_o diminish_v or_o disable_n of_o the_o spirit_n cold_a quality_n and_o fume_n or_o aura_n comprehend_v the_o foundation_n of_o all_o opinion_n concern_v opium_n that_o ever_o i_o read_v or_o hear_v of_o and_o consequent_o if_o those_o two_o fundamental_a opinion_n be_v refute_v all_o the_o superstructure_n that_o have_v be_v in_o this_o case_n must_v fall_v to_o the_o ground_n chap._n viii_o the_o author_n show_v just_a cause_n of_o his_o suspicion_n that_o all_o author_n have_v go_v upon_o a_o wrong_a foundation_n in_o their_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n i_o have_v show_v you_o that_o the_o general_a foundation_n of_o both_o ancient_n and_o modern_a author_n be_v that_o opium_n do_v diminish_v or_o disable_v the_o spirit_n and_o now_o i_o will_v plain_o show_v just_a cause_n of_o my_o suspicion_n of_o its_o insufficiency_n which_o be_v these_o 1._o i_o observe_v that_o all_o learned_a man_n be_v to_o this_o day_n high_o dissatisfy_v as_o to_o the_o cause_n and_o manner_n of_o the_o operation_n of_o opium_n notwithstanding_o all_o that_o have_v be_v write_v concern_v it_o and_o that_o it_o be_v the_o common_a cry_n on_o all_o hand_n that_o none_o have_v illustrate_v the_o operation_n of_o opium_n to_o any_o purpose_n or_o give_v any_o satisfaction_n therein_o and_o therefore_o learned_a physician_n be_v still_o as_o much_o upon_o the_o enquiry_n as_o ever_o they_o be_v it_o be_v much_o more_o civil_a and_o reasonable_a to_o suspect_v the_o foundation_n that_o all_o former_a author_n have_v build_v upon_o than_o a_o general_a failure_n in_o all_o the_o most_o judicious_a master_n builder_n that_o ever_o endeavour_v to_o build_v thereon_o for_o if_o all_o the_o best_a architect_n of_o the_o whole_a world_n fail_v to_o erect_v a_o firm_a superstructure_n upon_o any_o one_o foundation_n what_o can_v we_o think_v but_o that_o the_o foundation_n be_v infirm_a especial_o when_o as_o in_o our_o case_n no_o way_n that_o care_n judgement_n perspicacity_n and_o wit_n can_v invent_v or_o think_v of_o have_v be_v leave_v untried_a to_o build_v thereon_o so_o that_o though_o i_o modest_o call_v it_o a_o cause_n of_o suspicion_n it_o amount_v almost_o if_o not_o altogether_o to_o a_o demonstration_n that_o the_o foundation_n that_o all_o author_n have_v go_v upon_o be_v naught_o will_v not_o any_o consider_a man_n when_o he_o see_v all_o the_o judicious_a architect_n of_o the_o world_n fail_v to_o erect_v a_o firm_a building_n upon_o a_o certain_a foandation_n seek_v for_o another_o therefore_o who_o can_v blame_v i_o if_o i_o do_v and_o not_o blame_v they_o that_o do_v not_o the_o mean_a bricklayer_n or_o carpenter_n that_o shall_v be_v guilty_a of_o such_o stupidity_n as_o to_o attempt_v to_o build_v upon_o such_o a_o foundation_n as_o always_o deceive_v the_o builder_n will_v be_v think_v too_o great_a a_o blockhead_n to_o be_v employ_v in_o building_n 2._o i_o observe_v that_o most_o man_n do_v notwithstanding_o that_o foundation_n be_v agree_v upon_o think_v it_o impossible_a to_o explain_v the_o intricate_a various_a contradictory_n phenomena_n and_o mysterious_a effect_n of_o opium_n sit_v content_v and_o persuade_v that_o it_o operate_v by_o a_o occult_a quality_n whole_o unexplicable_a and_o particular_o reserve_v from_o the_o knowledge_n of_o mankind_n but_o nature_n work_v mechanical_o in_o weight_n measure_n etc._n etc._n therefore_o it_o be_v more_o than_o probable_a that_o it_o be_v only_o their_o be_v upon_o a_o wrong_a bottom_n make_v it_o seem_v absolute_o occult_a for_o it_o be_v impossible_a to_o find_v a_o thing_n where_o it_o be_v not_o or_o to_o build_v firm_o upon_o a_o insufficient_a foundation_n whereas_o have_v it_o be_v right_o and_o true_a it_o be_v not_o to_o be_v imagine_v but_o some_o or_o other_o will_v have_v thereupon_o do_v something_o that_o will_v have_v stand_v against_o all_o wind_n and_o storm_n which_o none_o have_v do_v 3._o i_o observe_v that_o none_o dare_v venture_v to_o lay_v the_o whole_a no_o nor_o one_o half_a of_o the_o burden_n of_o the_o phinomena_n or_o effect_n of_o opium_n upon_o that_o foundation_n foresee_v doubtless_o that_o it_o can_v not_o bear_v they_o and_o that_o if_o they_o lay_v any_o more_o weight_n thereon_o the_o whole_a will_v totter_v and_o fall_v to_o the_o ground_n the_o project_n in_o every_o hypothesis_n be_v to_o persuade_v man_n of_o the_o truth_n thereof_o and_o the_o only_a way_n to_o do_v it_o be_v to_o solve_v all_o phenomena_n thereby_o for_o if_o it_o fail_v but_o in_o one_o it_o be_v a_o infallible_a sign_n of_o its_o insufficiency_n there_o be_v no_o reason_n to_o omit_v any_o of_o the_o phenomena_n if_o they_o can_v have_v discern_v that_o the_o hypothesis_n will_v have_v bear_v they_o therefore_o as_o have_v be_v intimate_v it_o imply_v a_o confession_n of_o its_o incompetency_n 4._o i_o observe_v that_o ancient_a author_n write_v of_o opium_n before_o it_o come_v to_o be_v of_o common_a and_o general_a use_n in_o the_o daytime_n with_o healthy_a person_n as_o it_o since_o be_v in_o many_o nation_n to_o cause_v a_o gay_a pleasant_a and_o good_a humour_n take_v off_o sadness_n melancholy_a and_o anxiety_n to_o cause_n assurance_n boldness_n courage_n bravery_n magnanimity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n promptitude_n in_o business_n expediteness_n and_o serenity_n to_o excite_v to_o venery_n etc._n etc._n which_o effect_n can_v be_v explain_v by_o that_o supposition_n of_o disable_n the_o spirit_n and_o that_o they_o use_v opium_n only_a medicinally_n for_o the_o sake_n of_o such_o other_o effect_n as_o may_v be_v tolerable_o well_o explicate_v by_o that_o hypothesis_n so_o that_o they_o have_v not_o any_o occasion_n nor_o inducement_n to_o look_v any_o far_o the_o effect_n they_o give_v it_o for_o be_v only_o 1._o to_o cause_v sleep_n 2._o to_o take_v off_o pain_n 3._o to_o stop_v flux_n 4._o to_o compose_v the_o spirit_n 5._o to_o cause_v perspiration_n and_o sweat_n all_o which_o be_v not_o inconsistent_a with_o the_o hypothesis_n of_o diminish_v or_o disable_n the_o spirit_n as_o the_o other_o be_v and_o therefore_o may_v well_o deceive_v they_o for_o first_o sleep_n be_v cause_v by_o diminish_v the_o spirit_n by_o labour_n watch_v etc._n etc._n as_o be_v most_o notorious_a over_o the_o whole_a world_n so_o other_o thing_n that_o diminish_v the_o spirit_n as_o bleed_v vomit_v purge_v and_o many_o other_o cause_n of_o diminish_v thereof_o do_v incline_v we_o to_o sleep_v second_o indolence_n or_o exemption_n from_o pain_n be_v cause_v by_o nothing_o more_o than_o want_v of_o spirit_n as_o in_o paralytical_a case_n stuporâ—_n obstruction_n or_o compression_n of_o the_o nerve_n syncopes_fw-la leipothymy_n deliquium_n faint_n after_o bleed_v and_o sleep_v which_o as_o be_v say_v be_v so_o much_o cause_v by_o loss_n of_o spirit_n etc._n etc._n three_o flux_n be_v stop_v or_o moderate_v by_o nothing_o better_a than_o sleep_n which_o general_o as_o be_v say_v proceed_v from_o loss_n of_o spirit_n what_o also_o stop_v or_o moderate_v flux_n more_o than_o want_v of_o the_o sense_n of_o the_o irritation_n of_o humour_n and_o what_o take_v away_o sense_n more_o than_o want_v of_o spirit_n thus_o want_v of_o sense_n by_o the_o absence_n of_o the_o spirit_n in_o paralytical_a intestine_n stop_v flux_n thus_o fail_v a_o paralytical_a bladder_n to_o express_v the_o urine_n so_o a_o palsy_n of_o the_o membrane_n
of_o it_o and_o what_o be_v to_o be_v say_v thereof_o more_o at_o large_a hereafter_o i_o say_v then_o that_o hot_a spirituous_a cordial_n for_o such_o indeed_o all_o proper_a cordial_n be_v as_o brandy_n dr._n stephens_n water_n and_o suchlike_a have_v sulphureous_a particle_n so_o prepare_v and_o dispose_v towards_o heat_n or_o fire_n that_o they_o be_v as_o it_o be_v in_o potentia_fw-la proxima_fw-la or_o next_o disposition_n thereto_o be_v mighty_a apt_a to_o contract_v a_o heat_n as_o you_o find_v by_o spirit_n of_o wine_n or_o brandy_n keep_v the_o least_o time_n in_o a_o warm_a place_n or_o to_o come_v close_o to_o the_o matter_n in_o your_o mouth_n wherein_o be_v actuate_v by_o its_o heat_n they_o will_v as_o in_o a_o instant_n grow_v so_o hot_a and_o active_a that_o you_o can_v hardly_o bear_v they_o because_o particle_n of_o heat_n which_o penetrate_v any_o metal_n glass_n etc._n etc._n immediate_o as_o soon_o as_o apply_v thereto_o will_v much_o more_o easy_o and_o soon_o penetrate_v our_o soft_a part_n at_o mouth_n or_o the_o crusta_fw-la carnosa_fw-la at_o stomach_n and_o so_o reach_v the_o most_o sensile_a coat_n thereof_o please_v comfort_a and_o exciting_a the_o spiritus_fw-la insitos_fw-la as_o in_o a_o moment_n by_o their_o spirituous_a heat_n which_o we_o actual_o feel_v and_o sensible_o find_v to_o please_v and_o comfort_v the_o stomach_n but_o if_o some_o purge_v tincture_n have_v be_v put_v into_o the_o cordial_n or_o brandy_n this_o will_v not_o have_v soak_v through_o the_o crusta_fw-la carnosa_fw-la under_o some_o time_n and_o consequent_o not_o operate_v till_o it_o have_v this_o may_v be_v most_o manifest_o illustrate_v by_o some_o hot_a brandy_n or_o indeed_o any_o hot_a liquid_a put_v into_o a_o porous_a dish_n set_v upon_o one_o hand_n which_o present_o warm_v it_o but_o if_o the_o liquid_a be_v tinge_v with_o any_o thing_n that_o tincture_n will_v not_o reach_v the_o hand_n till_o the_o liquor_n which_o be_v its_o vehicle_n soak_v through_o which_o may_v be_v in_o a_o hour_n more_o or_o less_o according_a to_o the_o porosity_n of_o the_o wood_n which_o tincture_n be_v to_o be_v compare_v to_o the_o purgative_n at_o stomach_n hence_o it_o follow_v that_o all_o cordial_n shall_v be_v a_o spirituous_a liquid_a if_o intend_v for_o sudden_a refreshment_n which_o experience_n have_v teach_v and_o be_v give_v actual_o warm_v if_o a_o very_a nimble_a comfort_n be_v require_v though_o the_o great_a heat_n of_o the_o stomach_n above_o that_o of_o the_o mouth_n will_v general_o be_v sufficient_a thus_o may_v the_o stomach_n be_v please_v and_o comfort_v grieve_v and_o purge_v with_o the_o same_o draught_n but_o gracious_a providence_n have_v give_v the_o start_n to_o the_o cordial_n which_o immediate_o comfort_v we_o as_o a_o heater_n 30._o if_o opium_n operate_v by_o such_o fume_n it_o will_v at_o least_o in_o a_o liquid_a form_n begin_v its_o operation_n as_o soon_o as_o it_o be_v at_o stomach_n for_o it_o will_v begin_v to_o send_v up_o fume_n as_o soon_o as_o it_o begin_v to_o be_v warm_a which_o be_v present_o and_o be_v at_o a_o very_a considerable_a height_n of_o fume_v and_o consequent_o of_o operation_n in_o one_o minute_n which_o be_v about_o the_o space_n of_o seventy_o ordinary_a pulse_n but_o we_o do_v not_o find_v it_o begin_v to_o operate_v in_o that_o form_n under_o twenty_o thirty_o or_o forty_o minute_n which_o be_v much_o about_o the_o time_n that_o a_o more_o agreeable_a and_o not_o nauseated_a vomitive_a or_o purger_n begin_v to_o affect_v the_o sensile_a coat_n of_o the_o stomach_n and_o give_v intimation_n of_o their_o so_o do_v all_o which_o and_o the_o sense_n of_o pleasure_n that_o we_o actual_o then_o seel_v at_o stomach_n make_v it_o probable_a that_o it_o operate_v by_o affect_v the_o stomach_n pleasant_o and_o comfortable_o after_o the_o manner_n of_o generous_a wine_n as_o purger_n and_o vomatives_n do_v by_o affect_v it_o grievous_o all_o of_o they_o except_o the_o wine_n that_o please_v and_o comfort_v soon_o because_o of_o its_o particle_n of_o heat_n gain_v by_o fermentation_n operate_a much_o in_o the_o same_o time_n because_o they_o take_v like_o leisure_n to_o soak_v through_o the_o crusta_fw-la carnosa_fw-la to_o the_o sensile_a coat_n of_o the_o stomach_n 31._o all_o sensitive_a pleasure_n comfort_n etc._n etc._n be_v receive_v by_o the_o sense_n and_o though_o any_o part_n be_v some_o way_n benefit_v that_o have_v no_o sense_n no_o comfort_n will_v be_v perceive_v without_o perception_n none_o can_v say_v that_o he_o be_v comfort_v what_o fit_a part_n be_v there_o to_o be_v please_v and_o comfort_v by_o sensation_n than_o the_o stomach_n which_o have_v such_o exquisite_a sense_n that_o it_o can_v discern_v the_o vomitory_n particle_n in_o infusion_n of_o the_o grocus_n or_o regulus_n of_o antimony_n which_o no_o sensation_n but_o that_o at_o stomach_n can_v discern_v and_o so_o small_a that_o a_o thousand_o vomitory_n make_v thereof_o by_o infusion_n do_v not_o sensible_o diminish_v the_o grocus_n or_o regulus_n as_o to_o weight_n or_o bulk_n nor_o can_v i_o conceive_v where_o any_o sensible_a comfort_n can_v be_v perceive_v by_o a_o spoonful_n of_o cordial_n but_o at_o stomach_n where_o it_o actual_o be_v and_o upon_o who_o coat_n it_o immediate_o insist_o be_v it_o not_o there_o that_o we_o feel_v the_o comfort_n and_o where_o shall_v we_o find_v it_o but_o there_o what_o will_v the_o effluvium_n of_o a_o spoonful_n signify_v if_o mix_v with_o 100000_o time_n as_o much_o insensile_a blood_n and_o what_o part_n beside_o the_o stomach_n that_o the_o blood_n touch_v can_v be_v sensible_a of_o it_o so_o that_o if_o effluvium_n be_v grant_v it_o be_v thither_o they_o must_v return_v to_o cause_v any_o considerable_a pleasure_n or_o comfort_n but_o what_o need_v any_o reâ—urn_n of_o the_o inconsiderable_a effluvia_fw-la when_o the_o main_a body_n of_o the_o cordial_n yea_o all_z lie_v upon_o the_o stomach_n already_o i_o must_v forbear_v run_v into_o the_o business_n of_o other_o chapter_n have_v be_v tedious_a enough_o upon_o the_o subject_a of_o this_o and_o the_o rather_o because_o it_o be_v so_o general_a and_o so_o root_v a_o opinion_n in_o the_o mind_n of_o man_n in_o all_o age_n and_o in_o all_o sect_n of_o physician_n and_o natural_a philosopher_n that_o i_o can_v not_o say_v too_o much_o to_o endeavour_v to_o free_v the_o world_n from_o the_o slavery_n of_o such_o a_o imposition_n and_o the_o innumerable_a ill_a consequence_n of_o such_o a_o fundamental_a and_o overgrow_a error_n which_o certain_o must_v have_v be_v long_o since_o explode_v if_o ingenious_a man_n have_v first_o think_v and_o then_o speak_v free_o but_o the_o truth_n be_v there_o be_v many_o and_o great_a cause_n to_o the_o contrary_a as_o those_o intimate_v in_o the_o last_o paragraph_n and_o the_o mighty_a usefulness_n and_o ready_a officiousness_n of_o that_o opinion_n of_o fume_n to_o answer_v for_o all_o the_o more_o obscure_a and_o latent_fw-la cause_n of_o the_o malady_n and_o disaster_n of_o the_o brain_n and_o genus_fw-la nervosum_fw-la if_o any_o inquire_v or_o call_v for_o the_o cause_n of_o a_o vertigo_n the_o physician_n answer_v fume_n of_o epilepsy_n it_o be_v answer_v fume_n of_o scotomy_n it_o be_v fume_n of_o headache_n migraine_n coma_n caros_n lethargy_n etc._n etc._n it_o be_v fume_n of_o hysterick_n fit_n convulsion_n spasm_n cramp_n etc._n etc._n it_o be_v fume_n nay_o they_o answer_v as_o cause_n to_o all_o distillation_n catarrh_n epiphora_n or_o weep_v eye_n and_o all_o even_o ordinary_a tear_n all_o which_o they_o say_v be_v only_o these_o fume_n turn_v into_o water_n by_o the_o coldness_n of_o the_o brain_n as_o they_o be_v in_o a_o still_o or_o alembick_a so_o hot_a fume_n account_v for_o frenzy_n delirium_n rave_n etc._n etc._n so_o that_o however_o other_o head_n be_v the_o physician_n be_v be_v stuff_v therewith_o and_o all_o meteor_n of_o the_o microcosm_n upper_a region_n whether_o hot_a or_o cold_a be_v as_o those_o in_o the_o macrocosm_n form_v out_o of_o fume_n as_o he_o imagine_v thus_o you_o see_v all_o the_o opinion_n and_o hypothesise_n that_o have_v be_v concern_v the_o operation_n of_o opium_n to_o be_v most_o absurd_a and_o direct_o contrary_a to_o all_o sense_n reason_n and_o experience_n chap._n xi_o opium_n do_v not_o diminish_v or_o disable_v the_o spirit_n by_o any_o mean_n whatsoever_o have_v sufficient_o demonstrate_v that_o opium_n can_v diminish_v or_o disable_v the_o spirit_n by_o the_o cold_a quality_n of_o the_o ancient_n or_o fume_n of_o the_o modern_n and_o that_o neither_o of_o they_o have_v as_o much_o as_o any_o be_v i_o shall_v now_o add_v that_o opium_n do_v not_o diminish_v or_o disable_v the_o spirit_n by_o any_o other_o mean_n whatsoever_o i_o will_v not_o be_v mistake_v when_o i_o say_v that_o opium_n do_v not_o diminish_v or_o disable_v
the_o spirit_n by_o any_o mean_n for_o there_o be_v nothing_o so_o good_a in_o nature_n but_o will_v do_v it_o if_o use_v undue_o or_o immoderate_o as_o wine_n bread_n milk_n honey_n sugar_n beer_n etc._n etc._n in_o excess_n for_o i_o intend_v that_o it_o do_v not_o do_v it_o when_o due_o and_o moderate_o use_v 1._o that_o which_o refresh_v the_o weary_a and_o high_o prevent_v weariness_n must_v add_v to_o or_o excite_v the_o spirit_n which_o be_v direct_o contrary_a to_o diminish_v or_o disable_n they_o but_o opium_n do_v in_o a_o most_o eminent_a manner_n refresh_v the_o weary_v and_o prevent_v weariness_n therefore_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n some_o have_v be_v so_o silly_a and_o inadvertent_n as_o to_o object_n that_o it_o refresh_v the_o weary_a only_o by_o sleep_n it_o be_v matter_n of_o fact_n that_o it_o refresh_v they_o whether_o they_o sleep_v or_o no_o and_o that_o without_o fail_v as_o often_o as_o it_o be_v use_v in_o that_o case_n other_o that_o be_v no_o wise_a have_v say_v that_o it_o only_o take_v off_o the_o sense_n of_o weariness_n by_o stupify_a which_o happen_v by_o the_o diminish_n or_o disable_n of_o the_o animal_n spirit_n bare_a insensibleness_n can_v enable_v the_o spirit_n to_o labour_n with_o eminent_a briskness_n and_o alacrity_n as_o man_n most_o certain_o do_v after_o opium_n be_v take_v be_v fine_o enliven_v and_o invigorate_v as_o with_o generous_a wine_n if_o they_o do_v not_o know_v this_o to_o be_v true_a let_v they_o for_o shame_n hold_v their_o tongue_n till_o they_o know_v matter_n of_o fact_n which_o if_o they_o will_v not_o they_o proclaim_v themselves_o to_o be_v idle_a and_o impertinent_a babbler_n but_o if_o they_o will_v patient_o and_o wise_o abstain_v argue_v till_o they_o be_v satisfy_v as_o to_o matter_n of_o fact_n then_o will_v they_o be_v past_a opinion_n and_o hypothesis_n in_o that_o case_n for_o they_o will_v have_v sensible_a and_o certain_a knowledge_n of_o the_o contrary_a and_o the_o truth_n of_o what_o i_o say_v which_o will_v end_v all_o controversy_n and_o precarious_a squabble_n upon_o false_a supposition_n as_o the_o manner_n be_v that_o can_v lead_v they_o to_o what_o be_v right_o but_o by_o mere_a chance_n and_o never_o to_o a_o true_a knowledge_n that_o they_o be_v in_o the_o right_n which_o make_v it_o none_o in_o effect_n for_o they_o can_v do_v nothing_o with_o assurance_n but_o only_o suppose_v and_o hope_v they_o be_v in_o the_o right_n when_o they_o be_v as_o much_o out_o to_o their_o patient_n sorrow_n as_o physician_n have_v be_v in_o the_o cold_a quality_n and_o fume_n of_o opium_n it_o be_v true_a that_o a_o grain_n or_o two_o of_o opium_n will_n if_o a_o man_n compose_v himself_o sit_v or_o lie_v still_o cause_n a_o sleepiness_n equal_a to_o that_o cause_v by_o spend_v the_o spirit_n by_o a_o day_n be_v labour_n but_o spend_v of_o the_o spirit_n be_v not_o the_o only_a no_o nor_o best_a proportion_v or_o more_o adequate_a cause_n thereof_o as_o i_o have_v show_v if_o loss_n of_o spirit_n be_v the_o adequate_a cause_n of_o sleep_n how_o shall_v good_a and_o generous_a wine_n cause_n sleepiness_n after_o that_o eminent_a rate_n as_o it_o do_v in_o most_o people_n how_o shall_v the_o most_o please_a music_n incline_v such_o as_o lie_v or_o sit_v still_o to_o sleep_v but_o if_o one_o dance_n thereto_o it_o make_v he_o more_o lively_a and_o brisk_a than_o ordinary_a the_o like_a exact_o do_v wine_n and_o opium_n if_o man_n lie_v or_o sit_v still_o but_o otherwise_o they_o make_v they_o much_o more_o brisk_a and_o lively_a and_o able_a to_o undergo_v labour_n action_n etc._n etc._n which_o note_n that_o you_o may_v not_o any_o more_o wonder_n that_o enlivener_n and_o exciter_n of_o the_o spirit_n do_v cause_n sleep_v as_o well_o as_o diminisher_n thereof_o and_o observe_v that_o they_o be_v all_o please_a thing_n as_o music_n wine_n and_o opium_n which_o cause_n pleasant_a dream_n pleasant_a watch_n pleasant_a humour_n etc._n etc._n expect_v more_o of_o this_o matter_n in_o the_o follow_a chapter_n and_o all_o by_o degree_n according_a as_o i_o judge_v the_o prejudice_v world_n will_v bear_v thing_n for_o a_o great_a paradox_n how_o true_a soever_o must_v not_o be_v abrupt_o obtrude_v but_o gentle_o and_o gradual_o usher_v in_o by_o insinuate_v reason_v otherwise_o it_o will_v be_v entertain_v like_o a_o rude_a stranger_n that_o contradict_v a_o multitude_n in_o fashion_n and_o custom_n that_o they_o have_v always_o use_v and_o judge_v to_o be_v the_o very_o best_o however_o unblamable_a consider_v that_o if_o opium_n diminish_v or_o disable_v the_o spirit_n proportionable_a to_o the_o sleepiness_n that_o it_o cause_n as_o a_o hard_a day_n be_v labour_n do_v then_o if_o opium_n be_v give_v a_o man_n after_o a_o hard_a day_n be_v labour_n it_o will_v be_v as_o it_o be_v add_v another_o hard_a day_n be_v labour_v to_o cure_v it_o the_o day_n be_v labour_n and_o opium_n impair_n the_o spirit_n alike_o think_v what_o a_o miserable_a condition_n the_o poor_a man_n will_v be_v in_o especial_o if_o sleep_n do_v not_o make_v he_o some_o amends_o it_o will_v be_v such_o as_o be_v utter_o intolerable_a but_o so_o far_o be_v opium_n from_o any_o such_o effect_n that_o it_o refresh_v he_o though_o he_o sleep_v not_o at_o all_o after_o the_o hard_a day_n be_v labour_n and_o not_o only_o so_o but_o will_v enable_v he_o to_o work_v all_o the_o follow_a night_n with_o great_a alacrity_n if_o need_n require_v it_o what_o a_o condition_n will_v those_o be_v in_o who_o take_v a_o drachm_n of_o it_o twice_o a_o day_n for_o 10_o 20_o or_o 30_o year_n nay_o how_o can_v any_o possible_o do_v it_o for_o half_a 10_o day_n if_o a_o grain_n or_o two_o destroy_v the_o spirit_n so_o much_o as_o to_o cause_v sleepiness_n thereby_o as_o hard_a labour_n do_v which_o they_o must_v allow_v that_o assert_v it_o cause_n sleep_v by_o diminish_v or_o disable_n the_o spirit_n but_o some_o may_v say_v though_o very_o inconsiderate_o that_o it_o only_o disable_v they_o for_o the_o time_n of_o its_o operation_n that_o be_v strange_a indeed_o consider_v that_o even_o during_o that_o time_n they_o be_v most_o enable_v to_o work_n or_o labour_n though_o tire_v before_o and_o that_o it_o 2._o cause_n comfort_n refreshment_n ovation_n of_o the_o spirit_n all_o the_o time_n of_o its_o operation_n as_o wine_n moderate_o take_v do_v especial_o if_o people_n keep_v themselves_o in_o action_n labour_n etc._n etc._n otherwise_o indeed_o they_o may_v fall_v asleep_a upon_o the_o comfortable_a satisfaction_n contentation_n of_o mind_n and_o acquiescence_n of_o spirit_n that_o it_o occasion_n as_o wine_n do_v 3._o the_o first_o effect_n that_o we_o find_v of_o opium_n which_o may_v therefore_o probable_o be_v a_o very_a lead_n fundamental_a and_o significant_a effect_n be_v that_o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o incline_v he_o to_o sleep_n if_o not_o it_o make_v he_o gay_a good_a humour_a brave_a etc._n etc._n it_o be_v a_o pleasure_n so_o sweet_a and_o delicious_a that_o though_o i_o endeavour_v to_o express_v it_o by_o the_o ovation_n of_o the_o spirit_n upon_o joy_n a_o good_a genius_n inform_v a_o man_n or_o the_o helmâ—sians_n archaeus_n in_o his_o best_a humour_n or_o a_o continual_a vâ—real_a pleasure_n wine_n drink_v ad_fw-la hilaritatem_fw-la etc._n etc._n yet_o i_o doubt_v all_o my_o way_n of_o express_v it_o do_v come_v short_a of_o the_o charm_a complacency_n that_o it_o cause_n therefore_o if_o wine_n music_n a_o good_a meal_n agreeable_a frication_n of_o the_o head_n or_o back_o the_o sound_n of_o water_n etc._n etc._n do_v incline_v we_o to_o sleep_v by_o the_o pleasure_n thereof_o which_o lull_v and_o soothe_v we_o to_o it_o as_o be_v most_o certain_a if_o we_o sit_v or_o lie_v still_o much_o more_o must_v the_o high_a charm_n of_o opium_n cause_n it_o that_o it_o be_v a_o pleasure_n that_o affect_v by_o one_o of_o our_o sense_n namely_o by_o feel_v be_v indisputable_a for_o it_o be_v not_o a_o pleasure_n of_o the_o eye_n nose_n tongue_n or_o ear_n and_o it_o must_v be_v sensitive_a because_o cause_v by_o matter_n and_o that_o opium_n have_v doubtless_o the_o like_a effect_n upon_o brute_n who_o have_v no_o other_o pleasure_n but_o what_o be_v sensitive_a that_o it_o be_v at_o stomach_n be_v also_o evident_a where_o we_o can_v be_v please_v only_o by_o the_o sense_n of_o feel_v that_o it_o be_v involuntary_a and_o please_v we_o whether_o we_o will_v or_o no_o and_o that_o the_o same_o particle_n excite_v venery_n itch_a etc._n etc._n now_o all_o the_o sense_n especial_o feel_v and_o particular_o that_o at_o stomach_n be_v give_v we_o for_o
sensation_n of_o the_o sensile_a part_n which_o can_v well_o happen_v in_o that_o sound_a sleep_n wherein_o there_o be_v so_o little_a feel_v by_o reason_n of_o the_o say_a relaxation_n and_o because_o relaxation_n oppose_v contraction_n by_o which_o that_o shiver_a be_v promote_v such_o a_o relaxation_n and_o failure_n of_o feel_v thereupon_o be_v the_o true_a cause_n why_o opium_n put_v off_o ague_n fit_n etc._n etc._n so_o 20._o the_o relaxation_n in_o sleep_n stop_v vomit_v by_o take_v away_o the_o sense_n of_o the_o irritate_v cause_n and_o quiet_v as_o i_o have_v intimate_v all_o motion_n in_o general_a so_o sleep_v stop_n hiccough_n hemorrhage_n diary_n fever_n etc._n etc._n 21._o why_o watch_v labour_n or_o what_o impair_v the_o spirit_n and_o tire_v the_o sensitive_a soul_n incline_v we_o to_o sleep_v that_o be_v dispose_v the_o sensitive_a soul_n the_o only_a feeler_n of_o lassitude_n to_o give_v over_o contract_n the_o sensile_a part_n which_o as_o will_v plain_o appear_v by_o and_o by_o spend_v the_o spirit_n as_o sleep_v by_o relax_v they_o cause_v a_o recruit_v thereof_o to_o be_v short_a though_o one_o can_v hardly_o be_v too_o long_o in_o solve_v phenomena_n which_o be_v the_o proof_n of_o the_o truth_n of_o a_o man_n assertion_n the_o mechanical_a demonstration_n that_o i_o have_v make_v of_o the_o state_n of_o sleep_v and_o wake_v do_v so_o evident_o explicate_v all_o the_o phenomena_n of_o both_o that_o i_o be_o even_o ashamed_a to_o run_v any_o far_o upon_o such_o plain_a matter_n so_o obvious_a be_v thing_n when_o the_o truth_n be_v know_v and_o therefore_o have_v mention_v those_o circumstance_n and_o effect_n of_o sleep_n that_o main_o concern_v we_o i_o must_v give_v over_o lest_o the_o world_n shall_v think_v that_o i_o take_v all_o my_o reader_n to_o be_v idiot_n by_o use_v too_o many_o word_n in_o so_o obvious_a a_o thing_n or_o that_o i_o be_o no_o better_o for_o use_v they_o without_o cause_n for_o the_o truth_n of_o this_o matter_n seem_v to_o i_o to_o outshine_v all_o the_o argument_n i_o can_v make_v for_o it_o such_o splendour_n do_v truth_n show_v upon_o the_o first_o glimpse_n thereof_o as_o i_o take_v the_o account_n i_o give_v of_o sleep_n and_o watch_v to_o be_v for_o the_o opinion_n i_o have_v meet_v concern_v they_o be_v quite_o contrary_a to_o or_o very_o remote_a from_o what_o i_o have_v state_v 1._o they_o go_v quite_o contrary_a to_o it_o that_o say_v that_o the_o animal_n spirit_n be_v expanded_a and_o the_o pore_n of_o the_o brain_n etc._n etc._n more_o open_a and_o consequent_o more_o lax_n in_o watch_v as_o willis_n and_o several_a other_o who_o therefore_o say_v that_o coffee_n volatile_a salt_n etc._n etc._n be_v antihypnotick_n or_o good_a against_o too_o much_o sleepiness_n because_o they_o cause_v a_o expansion_n of_o the_o spirit_n and_o open_v the_o pore_n of_o the_o brain_n suppose_v forsooth_o that_o they_o march_v up_o and_o down_o and_o so_o keep_v the_o great_a stir_n upon_o the_o false_a imagination_n of_o their_o road_n be_v more_o open_a which_o as_o be_v prove_v be_v real_o more_o close_a coffee_n keep_v we_o from_o sleep_n by_o dry_v bind_a and_o both_o way_n constr_v the_o vessel_n as_o also_o by_o a_o wide_a grate_a quality_n which_o therefore_o do_v irritate_fw-la they_o to_o contract_v beside_o that_o the_o saline_n particle_n cause_v a_o agitation_n may_v contribute_v thereto_o so_o that_o by_o constr_v and_o agitate_v it_o direct_o oppose_v sleep_n which_o proceed_v from_o relaxation_n and_o quietness_n 2._o they_o be_v very_o remote_a from_o the_o mark_n that_o say_v as_o wedeliâ—s_a assert_n all_o do_v that_o vapour_n be_v the_o cause_n of_o natural_a sleep_n which_o bear_v no_o manner_n of_o proportion_n thereto_o as_o be_v show_v as_o they_o be_v also_o who_o mâ—dly_o talk_v that_o the_o animal_n spirit_n which_o have_v neither_o life_n sense_n motion_n or_o election_n do_v of_o themselves_o retire_v very_o know_o to_o the_o brain_n in_o sâ—eep_n and_o leave_v the_o limb_n etc._n etc._n destitute_a of_o they_o whereas_o as_o have_v be_v mechanical_o prove_v they_o have_v more_o room_n than_o that_o at_o other_o time_n in_o 〈◊〉_d limb_n and_o all_o the_o sensile_a part_n but_o i_o will_v not_o argue_v against_o such_o senseless_a and_o precarious_a absurdity_n it_o be_v not_o worth_a the_o while_n especial_o since_o the_o truth_n be_v manifest_o discover_v it_o will_v not_o have_v be_v so_o silly_a to_o have_v affirm_v the_o quite_o contrary_a viz._n that_o the_o animal_n spirit_n be_v force_v into_o the_o soft_a and_o yield_a brain_n in_o watch_v by_o the_o vigilative_a contraction_n of_o all_o the_o senfile_v part_n repel_v they_o as_o when_o cold_a repel_v they_o by_o a_o strong_a contraction_n of_o the_o part_n and_o cause_v a_o stupor_n or_o sleep_n thereof_o as_o they_o call_v it_o but_o what_o have_v we_o to_o do_v with_o such_o insufferable_a trash_n therefore_o bid_v it_o adieu_n let_v we_o pursue_v our_o business_n that_o it_o be_v the_o sensitive_a soul_n and_o nothing_o but_o it_o have_v that_o contract_n power_n be_v evident_a 1._o because_o it_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n as_o such_o and_o that_o nothing_o beside_o it_o have_v any_o life_n perception_n motion_n or_o power_n and_o therefore_o must_v rest_v till_o they_o be_v move_v 2._o because_o that_o when_o the_o sensitive_a soul_n be_v divert_v by_o intense_a pleasure_n from_o attend_v his_o business_n immediate_o relaxation_n follow_v as_o in_o the_o pleasure_n of_o the_o act_n of_o venery_n by_o wine_n joy_n etc._n etc._n in_o which_o you_o have_v all_o the_o effect_n of_o relaxation_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la plentiful_a perspiration_n floridity_n of_o the_o skin_n a_o large_a pulse_n and_o sometime_o a_o considerable_a failure_n of_o sense_n and_o motion_n as_o in_o the_o most_o pleasant_a time_n of_o the_o venereal_a act_n deliquiums_n drunkenness_n syncopes_fw-la or_o ecstasy_n upon_o intense_a pleasure_n which_o be_v very_o proper_o call_v ecstasy_n leipothymy_n leipopsychy_n etc._n etc._n which_o signify_v the_o soul_n leave_v we_o without_o his_o help_n by_o contraction_n which_o he_o then_o do_v not_o exercise_n as_o be_v charm_v and_o whole_o take_v up_o with_o pleasure_n this_o be_v the_o true_a cause_n of_o all_o deliquium_n etc._n etc._n upon_o pleasure_n joy_n etc._n etc._n all_o which_o cause_n great_a relaxation_n and_o thereby_o loss_n of_o sense_n and_o motion_n as_o be_v its_o necessary_a consequence_n 3._o because_o grievous_a sensation_n which_o belong_v only_o to_o the_o sensitive_a soul_n put_v we_o immediate_o out_o of_o sleep_n into_o a_o vigilative_a contraction_n 4._o because_o the_o sensitive_a soul_n can_v when_o we_o be_v sleepy_a oppose_v it_o by_o continue_v the_o vigilative_a contraction_n which_o prove_v vigilative_a contraction_n to_o be_v in_o his_o power_n note_v that_o there_o be_v also_o other_o sort_n of_o leipothymy_n deliquium_n etc._n etc._n upon_o the_o sensitive_a soul_n be_v overtired_n whereof_o natural_a sleep_n be_v but_o a_o common_a and_o ordinary_a degree_n that_o happen_v of_o course_n for_o our_o relief_n or_o overbear_v with_o some_o fatigue_n etc._n etc._n as_o when_o somewhat_o grieve_v at_o stomach_n and_o that_o it_o have_v lay_v about_o it_o all_o manner_n of_o way_n by_o vomit_v convulsive_a motion_n etc._n etc._n to_o be_v rid_v of_o it_o till_o it_o can_v work_v no_o long_o whereupon_o it_o lay_v down_o the_o cudgel_n desi_v from_o all_o further_a endeavour_n by_o contraction_n yield_v itself_o to_o ease_n see_v all_o strive_v be_v to_o no_o effect_n so_o that_o though_o this_o deliquium_fw-la and_o the_o former_a differ_v in_o their_o first_o cause_n yet_o do_v they_o agree_v in_o the_o last_o and_o immediate_a viz._n the_o sensitive_a soul_n be_v not_o attend_v his_o business_n of_o contraction_n whereupon_o follow_v a_o mighty_a relaxation_n as_o appear_v by_o the_o deadness_n or_o relaxation_n of_o the_o cornea_n dilatation_n of_o the_o pupil_n a_o great_a laxity_n of_o all_o part_n a_o large_a pulse_n or_o none_o very_o plentiful_a perspiration_n stop_v of_o hemorrhage_n and_o all_o flux_n that_o require_v contraction_n etc._n etc._n which_o happen_v both_o upon_o the_o account_n of_o the_o great_a relaxation_n itself_o as_o have_v be_v show_v and_o the_o almost_o absolute_a rest_n of_o all_o thing_n by_o the_o sensitive_a soul_n withdraw_a himself_n from_o business_n more_o than_o in_o sleep_n itself_o i_o therefore_o observe_v the_o degree_n of_o sleep_n etc._n etc._n do_v note_n that_o god_n and_o nature_n use_v a_o due_a proportion_n in_o all_o thing_n the_o sensitive_a soul_n use_v several_a degree_n of_o relaxation_n according_a as_o he_o be_v tire_v and_o refection_n be_v want_v hence_o it_o be_v that_o such_o as_o be_v much_o tire_v sleep_n more_o profound_o that_o our_o first_o
sleep_v be_v the_o sound_a and_o that_o sleep_v gradual_o decline_v in_o degree_n as_o we_o be_v recruit_v till_o we_o awake_v the_o near_a which_o we_o be_v the_o more_o we_o dream_v the_o state_n of_o dream_v be_v a_o kind_n of_o twilight_n between_o sound_a sleep_n and_o awake_v or_o between_o a_o full_a somniferous_a relaxation_n and_o vigilative_a contraction_n and_o as_o the_o sensitive_a soul_n use_v all_o degree_n of_o contraction_n below_o that_o of_o the_o vigilative_a till_o it_o come_v to_o bare_a compression_n of_o the_o air_n so_o it_o can_v exercise_v super-vigilative_a contraction_n if_o i_o may_v so_o call_v it_o that_o be_v much_o high_a degree_n thereof_o than_o what_o be_v requisite_a ordinary_o for_o a_o state_n of_o vigilancy_n as_o in_o case_n of_o danger_n to_o the_o animal_n fright_v terror_n grievous_a passion_n and_o sensation_n by_o which_o mean_v the_o animal_n spirit_n be_v more_o compress_v than_o under_o the_o ordinary_a vigilative_a contraction_n sensation_n grow_v more_o nice_a and_o smart_a and_o motion_n more_o prompt_a and_o vigorous_a they_o always_o go_v together_o for_o the_o defence_n of_o the_o animal_n by_o extraordinary_a flight_n repulsion_n or_o otherwise_o hence_o it_o be_v upon_o fear_n terror_n grievous_a passion_n or_o sensation_n which_o manifest_o prove_v the_o be_v of_o such_o a_o extraordinary_a contraction_n upon_o such_o occasion_n that_o 1._o perspiration_n sail_v in_o a_o yet_o high_o degree_n than_o under_o bare_a or_o ordinary_a vigilative_a contraction_n as_o appear_v by_o infallible_a statick_a experiment_n and_o demonstration_n 2._o it_o be_v by_o reason_n of_o the_o say_v defensive_a contraction_n for_o so_o i_o call_v it_o because_o it_o be_v excite_v in_o a_o extraordinary_a manner_n for_o the_o defence_n of_o the_o animal_n in_o time_n of_o need_n or_o great_a exigence_n that_o in_o fright_v terror_n etc._n etc._n our_o hair_n dog_n etc._n etc._n do_v stand_v on_o end_n or_o more_o upright_o 1._o because_o the_o pore_n do_v by_o that_o violent_a contraction_n strict_o close_a about_o the_o root_n of_o the_o hair_n that_o it_o can_v swag_v incline_v or_o yield_v any_o way_n by_o reason_n of_o its_o weight_n etc._n etc._n as_o when_o the_o skin_n be_v more_o lax_n and_o soft_a and_o the_o pore_n wherein_o the_o hair_n be_v fix_v more_o open_a 2._o because_o which_o be_v the_o main_a reason_n the_o say_a contraction_n render_v the_o oblique_a pore_n more_o upright_o as_o suppose_v the_o pore_n and_o hair_n do_v natural_o stand_v oblique_o as_o they_o do_v to_o carry_v off_o wet_a etc._n etc._n as_o in_o fig._n 1._o fig_n i_o fig_n two_o and_o that_o a_o in_o fig._n 1._o be_v by_o the_o say_a contraction_n bring_v near_a to_o ay_o as_o much_o as_o be_v from_o a_o to_o o_o then_o will_v the_o pore_n and_o hair_n stand_v upright_o as_o in_o fig._n 2._o and_o the_o skin_n a_o o_o e_o i_o s_o contract_v and_o bring_v within_o the_o prick_v perpendicular_o whereas_o in_o fig._n 1._o it_o excure_v beyond_o the_o perpendicular_a n_z m_z as_o much_o as_o be_v from_o a_o to_o o._n 3._o for_o the_o same_o reason_n it_o be_v that_o the_o face_n in_o grievous_a passion_n and_o sensation_n as_o acute_a pain_n etc._n etc._n be_v contort_a and_o wring_v awry_o as_o you_o see_v in_o person_n that_o cry_v because_o of_o grievance_n after_o the_o same_o manner_n as_o when_o they_o strive_v to_o lift_v up_o a_o great_a weight_n and_o that_o at_o the_o same_o time_n tear_n and_o moisture_n at_o nose_n and_o mouth_n be_v squeeze_v out_o by_o the_o same_o contraction_n which_o make_v people_n use_v the_o say_v of_o casting_n snot_n about_o when_o man_n cry_v it_o be_v for_o the_o same_o reason_n that_o people_n mouth_n water_n extreme_o when_o they_o be_v trim_v with_o a_o bad_a razor_n that_o put_v they_o to_o pain_n which_o contract_v the_o part_n and_o squeeze_v out_o the_o spital_n 4._o the_o pulse_n grow_v sensible_o narrow_a and_o hard_a by_o the_o same_o contraction_n 5._o it_o be_v by_o the_o contraction_n upon_o grievous_a sensation_n that_o our_o mouth_n water_n very_o much_o upon_o a_o nausea_n at_o stomach_n because_o of_o the_o continuity_n of_o the_o membrane_n of_o the_o mouth_n and_o stomach_n 6._o the_o same_o contraction_n be_v the_o true_a reason_n why_o people_n upon_o hunger_n which_o be_v a_o grievous_a sensation_n at_o stomach_n have_v so_o much_o moisture_n or_o spital_n in_o their_o mouth_n and_o so_o much_o the_o more_o when_o they_o see_v good_a victual_n and_o can_v have_v it_o because_o the_o grievance_n which_o cause_v the_o contraction_n that_o squeeze_v it_o out_o be_v by_o so_o much_o the_o great_a this_o be_v the_o cause_n why_o the_o mouth_n water_n when_o hungry_a people_n see_v or_o smell_v good_a victual_n by_o the_o same_o contraction_n moisture_n be_v squeeze_v out_o into_o the_o oesophagus_n or_o gullet_n and_o the_o menstruum_fw-la into_o the_o stomach_n at_o the_o same_o time_n where_o observe_v god_n good_a and_o wise_a providence_n that_o hunger_n which_o call_v for_o meat_n at_o the_o same_o time_n provide_v spital_n to_o lubricate_v it_o for_o swollow_v and_o to_o help_v digestion_n render_v the_o gullet_n slippery_a and_o distensible_a and_o cause_v the_o menstruum_fw-la to_o flow_v more_o abundant_o into_o the_o stomach_n and_o all_o this_o when_o most_o need_v and_o that_o exact_o in_o proportion_n to_o the_o hunger_n or_o grievous_a sensation_n that_o cause_v the_o contraction_n it_o be_v well_o worth_a your_o nothing_o that_o god_n wisdom_n do_v always_o cause_v the_o want_n of_o what_o be_v necessary_a in_o sensile_a creature_n to_o be_v the_o solicit_v and_o urge_v cause_n for_o supply_v that_o a_o due_a proportion_n may_v be_v observe_v between_o the_o supply_n and_o the_o want_n which_o may_v upon_o the_o tell_n of_o it_o appear_v so_o plain_a a_o case_n that_o it_o be_v scarce_o worth_a the_o mention_v but_o believe_v i_o it_o be_v so_o little_o observe_v as_o plain_a as_o it_o may_v seem_v to_o be_v that_o people_n have_v and_o do_v err_v extravagant_o for_o want_n of_o note_v it_o which_o if_o they_o have_v note_v they_o can_v never_o have_v say_v that_o vapour_n or_o the_o retire_n of_o spirit_n into_o the_o brain_n etc._n etc._n be_v the_o cause_n or_o call_v of_o natural_a sleep_n nor_o feign_v menstruum_n to_o be_v the_o cause_n of_o hunger_n but_o will_v have_v due_o consider_v what_o be_v main_o supply_v by_o eat_v or_o recruit_v by_o sleep_v etc._n etc._n and_o then_o have_v nothing_o to_o do_v but_o to_o conclude_v the_o defect_n of_o that_o to_o have_v be_v the_o cause_n that_o solicit_v for_o the_o supply_n in_o proportion_n to_o the_o defect_n which_o if_o observe_v will_v most_o natural_o and_o easy_o lead_v you_o to_o the_o true_a knowledge_n of_o the_o cause_n of_o all_o appetite_n in_o a_o animal_n upon_o a_o few_o minute_n consideration_n for_o want_v of_o which_o most_o plain_a and_o one_o will_v think_v very_o obvious_a method_n the_o deviate_a world_n have_v sad_o puzzle_v itself_o about_o the_o cause_n of_o hunger_n thirst_v sleep_v and_o the_o like_a to_o this_o day_n and_o still_o be_v in_o dispute_n about_o they_o of_o which_o though_o my_o advertent_fw-la reader_n may_v well_o prevent_v i_o by_o use_v that_o natural_a method_n i_o shall_v god_n will_v give_v a_o account_n in_o my_o tract_n of_o animal_n mechanism_n only_a note_n here_o that_o i_o do_v not_o mean_v bare_a privative_a defect_n as_o such_o to_o be_v the_o positive_a cause_n but_o that_o the_o defect_n of_o what_o keep_v or_o guard_v the_o stomach_n etc._n etc._n from_o the_o grievance_n cause_v other_o matter_n to_o grieve_v it_o cause_n hunger_n etc._n etc._n without_o which_o mean_n no_o proportion_n can_v be_v observe_v between_o hunger_n and_o what_o take_v it_o away_o or_o our_o food_n 7._o the_o same_o defensive_a contraction_n do_v upon_o grievous_a sensation_n as_o pain_n cold_a terror_n etc._n etc._n cause_n a_o corrugation_n of_o the_o scrotum_fw-la contract_v the_o skin_n into_o little_a tubercle_n like_o that_o of_o a_o goose-skin_n etc._n etc._n 8._o by_o it_o upon_o grievous_a sensation_n as_o by_o squeeze_v the_o nose_n very_o hard_o pull_v the_o hair_n sand_n or_o any_o such_o thing_n in_o the_o eye_n or_o a_o grievance_n by_o the_o volatile_a particle_n of_o onion_n mustard_n horse-radish-root_n etc._n etc._n the_o part_n and_o membrane_n about_o the_o eye_n contract_v squeeze_v out_o tear_n that_o what_o grieve_v the_o eye_n may_v thereby_o be_v wash_v away_o or_o qualify_v as_o much_o as_o the_o tear_n can_v do_v it_o 9_o by_o this_o contraction_n repel_v the_o blood_n the_o skin_n grow_v pale_a by_o cold_a fear_v pain_n etc._n etc._n which_o also_o close_v the_o pore_n stop_v sweat_n as_o in_o a_o moment_n you_o will_v have_v a_o account_n hereafter_o how_o contraction_n may_v cause_v sweat_n
which_o argue_v that_o the_o specific_a combination_n of_o the_o oily_a and_o volatile_a part_n baffle_v all_o coction_n digestion_n circulation_n and_o percolation_n that_o have_v happen_v in_o the_o body_n dioscorides_n and_o aeginela_fw-la speak_v of_o opium_n say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o be_v the_o smell_n of_o the_o medicament_n be_v expanded_a over_o the_o whole_a body_n which_o thing_n of_o its_o nature_n do_v as_o garlic_n onion_n semen_n animale_a which_o cause_v rankness_n all_o over_o male_a creature_n as_o ram_n boar_n bull_n etc._n etc._n 14._o le_fw-fr febure_n in_o his_o chemistry_n part_v 2._o p._n 33_o say_v that_o opium_n have_v a_o volatile_a salt_n inseparable_o mix_v with_o sulphur_n or_o oily_a part_n 15._o wedelius_n in_o his_o opiologia_fw-la lib._n 2._o sect._n 1_o cap._n 4._o p._n 91._o speak_v of_o opium_n say_v sal_fw-la ejus_fw-la cum_fw-la sulphur_n intime_fw-la combinatum_fw-la sudores_fw-la efficit_fw-la that_o be_v its_o salt_n be_v intimate_o combine_v with_o sulphur_n or_o oil_n cause_v sweat_n and_o lib._n 2._o p._n 143._o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d obtinuit_fw-la non_fw-la facile_fw-la dissipabilem_fw-la that_o be_v it_o have_v a_o contexture_n not_o easy_o dissipable_a 18._o all_o know_v how_o apt_a volatile_a salt_n and_o oily_a part_n be_v to_o combine_v therefore_o opium_n act_n and_o produce_v its_o usual_a good_a effect_n by_o a_o sal-volatile-oleosum_a somewhat_o more_o active_a than_o that_o in_o our_o membrane_n who_o principle_n be_v most_o intimate_o and_o strict_o combine_v and_o so_o that_o it_o be_v qualify_v in_o the_o high_a degree_n for_o our_o purpose_n because_o 1._o it_o agree_v in_o principle_n with_o our_o membrane_n 2._o that_o its_o sal-volatile-oleosum_a be_v more_o active_a and_o vigorous_a than_o that_o of_o the_o membrane_n to_o actuate_v and_o excite_v the_o spiritus_fw-la insiti_fw-la and_o fine_o to_o tickle_v and_o gratify_v the_o membrane_n 3._o that_o the_o volatile_a salt_n and_o oily_a part_n be_v so_o intimate_o combine_v do_v delicious_o qualify_v one_o the_o other_o for_o that_o purpose_n while_o the_o oily_a smooth_v and_o lenify_v the_o volatile_a salt_n and_o the_o volatile_a salt_n actuate_v and_o quicken_v the_o oily_a and_o that_o be_v so_o combine_v 4._o both_o conspire_v to_o a_o permanent_a and_o exalt_a pleasure_n of_o the_o membrane_n especial_o at_o stomach_n and_o the_o venereal_a part_n where_o they_o be_v so_o exquisite_o dispose_v for_o sensation_n therefore_o the_o sal-volatile-oleosum_a of_o opium_n separate_v from_o its_o rosin_n be_v most_o consummate_a and_o best_a qualify_v that_o possible_o can_v be_v imagine_v to_o please_v gratify_v and_o fine_o to_o titillate_v our_o membrane_n or_o organ_n of_o sensation_n which_o be_v the_o thing_n require_v i_o can_v better_o illustrate_v its_o nature_n than_o by_o the_o most_o exalt_a thing_n in_o a_o animal_n viz._n it_o be_v semen_n therefore_o for_o confirmation_n of_o its_o principle_n and_o excellency_n therein_o i_o will_v consider_v its_o likeness_n and_o agreement_n therewith_o 1._o in_o be_v both_o a_o shall_v volatile-oleosum_a 2._o in_o have_v a_o more_o active_a vigorous_a and_o exalt_v sal-volatile-oleosum_a than_o any_o part_n of_o the_o animal_n 3._o in_o have_v the_o volatile_a salt_n and_o oleous_a particle_n intimate_o combine_v for_o semen_n animale_a will_v as_o opium_n keep_v very_o long_o uncorrupted_a as_o appear_v by_o its_o long_a stay_n in_o the_o vesiculae_fw-la seminales_fw-la of_o some_o animal_n that_o do_v not_o excern_v it_o in_o many_o year_n 4._o in_o that_o both_o be_v apt_a to_o mix_v with_o all_o fort_n of_o menstruum_n and_o both_o mole_n minimum_n virtute_fw-la maxima_fw-la 5._o in_o have_v much_o the_o same_o smell_n viz._n a_o rank_n and_o vehement_a one_o 6._o in_o taint_v the_o body_n therewith_o as_o have_v be_v show_v 7._o in_o be_v much_o of_o the_o same_o weight_n as_o appear_v by_o both_o sink_n in_o water_n etc._n etc._n 8._o the_o taste_n must_v in_o all_o probability_n have_v a_o rankness_n in_o it_o like_o that_o of_o opium_n because_o it_o give_v a_o rank_a taste_n to_o the_o whole_a body_n of_o male_a creature_n 9_o both_o excite_v venery_n cause_n erection_n venereal_a fury_n and_o nocturnal_a pollution_n etc._n etc._n 10._o both_o cause_n boldness_n courage_n and_o magnanimity_n which_o be_v reckon_v among_o the_o effect_n of_o opium_n and_o be_v the_o common_a effect_n of_o plenitude_n of_o seed_n in_o animal_n that_o be_v otherwise_o pusillanimous_a in_o time_n of_o copulation_n so_o modest_a and_o sheepish_a boy_n grow_v much_o more_o assure_v â—old_a and_o as_o they_o common_o call_v it_o manlike_a upon_o puberty_n and_o girl_n grow_v more_o womanlike_a in_o their_o disposition_n and_o it_o be_v my_o observation_n that_o the_o man_n who_o breed_v most_o of_o the_o sem._n virile_a be_v general_o if_o not_o always_o the_o most_o valiant_a 11._o both_o do_v cause_n a_o great_a relaxation_n upon_o the_o pleasure_n thereof_o as_o appear_v after_o a_o good_a do_v of_o opium_n and_o upon_o emission_n of_o the_o other_o by_o the_o deadness_n of_o the_o eye_n or_o laxity_n of_o the_o cornea_n in_o both_o case_n dilatation_n of_o the_o pupil_n floridity_n of_o the_o skin_n large_a perspiration_n laxity_n of_o the_o limb_n sleepiness_n loss_n of_o memory_n and_o sense_n alienation_n of_o the_o mind_n a_o wide_a pulse_n indolence_n loss_n of_o feel_v in_o both_o case_n and_o other_o sign_n of_o relaxation_n 12._o both_o opium_n and_o puberty_n cause_v a_o growth_n of_o the_o penis_n breast_n and_o increase_v milk_n by_o reason_n of_o the_o relaxation_n that_o they_o cause_n which_o as_o in_o sleep_n cause_v the_o great_a nutrition_n but_o of_o the_o manner_n how_o it_o happen_v upon_o relaxation_n more_o hereafter_o if_o there_o be_v occasion_n hence_o it_o be_v 13._o that_o both_o opium_n and_o puberty_n be_v apt_a to_o bring_v down_o the_o menses_fw-la and_o open_v the_o viae_fw-la by_o the_o relaxation_n and_o that_o marriage_n or_o the_o pleasure_n of_o venereal_a act_n do_v by_o the_o like_a relaxation_n promote_v the_o menses_fw-la that_o both_o opium_n and_o such_o act_n be_v apt_a to_o cause_n miscarriage_n by_o relax_v the_o neck_n of_o the_o womb_n etc._n etc._n 14._o both_o cause_n sadness_n and_o dejection_n when_o the_o operation_n be_v over_o as_o indeed_o pleasure_n general_o do_v especial_o if_o intense_a 15._o both_o opium_n and_o sem._n animale_a prevent_v lassitude_n and_o cause_n euphory_n or_o easy_a undergo_n of_o labour_n hence_o it_o be_v that_o stone_n horse_n will_v not_o be_v so_o soon_o tire_v when_o full_a thereof_o and_o quick_o recover_v if_o tire_a which_o may_v doubtless_o be_v observe_v in_o other_o animal_n but_o that_o they_o be_v not_o use_v to_o labour_n and_o so_o not_o obvious_a to_o be_v observe_v 16._o author_n do_v say_v that_o sem._n virile_a take_v of_o venereal_a impotence_n procure_v love_n etc._n etc._n which_o doubtless_o must_v be_v by_o exciting_a to_o venery_n as_o opium_n do_v thus_o the_o genitals_o of_o buck_n boar_n buck_n of_o hare_n cock_n etc._n etc._n do_v as_o opium_n excite_v venery_n and_o the_o seed_n of_o animal_n as_o of_o a_o camel_n and_o the_o aforesaid_a creature_n come_v to_o be_v esteem_v hypnotick_n and_o doubtless_o all_o animal_n seed_n especial_o of_o the_o more_o salaceous_a creature_n be_v a_o opiate_n in_o some_o degree_n to_o be_v short_a the_o main_a if_o not_o all_o the_o difference_n in_o their_o effect_n arise_v only_o 1._o from_o the_o different_a part_n that_o they_o affect_v because_o opium_n affect_v the_o stomach_n the_o venereal_a and_o all_o the_o membrane_n in_o general_a and_o sem._n animale_a only_a the_o venereal_a part_n immediate_o though_o a_o intense_a pleasure_n of_o one_o part_n do_v affect_v the_o whole_a 2._o that_o opium_n do_v affect_v with_o a_o sense_n of_o pleasure_n more_o permanent_a viz._n for_o many_o hour_n as_o have_v be_v say_v and_o that_o the_o pleasure_n of_o the_o other_o be_v momentary_a therefore_o opium_n act_n by_o cause_v a_o intense_a permanent_a and_o charm_a pleasure_n of_o the_o membrane_n in_o general_a but_o more_o particular_o of_o the_o stomach_n and_o venereal_a part_n as_o be_v more_o exquisite_o dispose_v for_o sensation_n for_o the_o preservation_n of_o the_o individuum_fw-la and_o species_n it_o can_v be_v much_o wonder_v at_o consider_v our_o active_a principle_n be_v a_o sal-volatile-oleosum_a and_o that_o opium_n be_v such_o and_o that_o we_o natural_o carry_v a_o opiate_n within_o we_o that_o in_o some_o case_n our_o ordinary_a sal-volatile-oleosum_a or_o that_o of_o the_o choler_n semen_n etc._n etc._n be_v by_o some_o accident_n exalt_v towards_o the_o nature_n of_o opium_n may_v have_v the_o effect_v of_o a_o opiate_n upon_o we_o by_o cause_v sopor_n and_o lethargic_a distemper_n fuâ—or_fw-la uterinus_fw-la by_o titillation_n etc._n etc._n thus_o the_o spume_n of_o some_o male_a animal_n mummy_n etc._n etc._n
only_o in_o those_o membrane_n but_o also_o in_o the_o more_o exquisite_o dispose_v membrane_n for_o sensation_n at_o stomach_n and_o soon_o after_o all_o over_o the_o body_n 5._o it_o prevent_v and_o take_v away_o grief_n fear_v anxiety_n peevishness_n fretfulness_n etc._n etc._n for_o the_o aforesaid_a reason_n which_o cause_n a_o blithe_a gay_a and_o good_a humour_n promptitude_n courage_n etc._n etc._n for_o it_o be_v impossible_a to_o be_v gay_a and_o good_a humour_a serene_a cheerful_a courageous_a and_o magnanimous_a and_o at_o the_o same_o time_n sorrowful_a fearful_a peevish_a fretful_a etc._n etc._n if_o the_o bare_a sense_n of_o a_o ordinary_a meal_n of_o meat_n at_o stomach_n which_o cause_v but_o a_o slow_a pleasure_n in_o comparison_n with_o opium_n take_v off_o the_o peevishness_n fretfulness_n etc._n etc._n that_o the_o grievous_a sensation_n of_o hunger_n cause_n how_o much_o more_o must_v the_o intense_a and_o charm_a pleasure_n cause_v by_o opium_n that_o be_v so_o agreeable_a even_o far_o beyond_o wine_n itself_o as_o have_v be_v set_v forth_o take_v away_o all_o ill_a humour_n fretfulness_n peevishness_n etc._n etc._n obj._n but_o it_o may_v be_v say_v that_o sleepiness_n which_o depend_v also_o upon_o relaxation_n as_o the_o effect_n of_o pleasure_n do_v cause_v a_o peevish_a fretful_a humour_n as_o be_v common_o observe_v ans._n it_o be_v so_o far_o otherwise_o in_o the_o case_n of_o opium_n that_o it_o be_v quite_o contrary_a for_o 1._o the_o sleepy_a be_v not_o peevish_a unless_o you_o put_v they_o by_o some_o mean_v out_o of_o the_o pleasure_n of_o enjoy_v sleep_n or_o relaxation_n for_o if_o you_o let_v they_o alone_o they_o will_v not_o trouble_v you_o with_o peevishness_n nor_o any_o ill_a humour_n but_o it_o be_v the_o call_v they_o from_o their_o relaxed_a condition_n to_o the_o grievous_a task_n of_o contraction_n that_o vex_v they_o so_o that_o it_o be_v the_o want_n of_o continue_v under_o the_o relaxation_n that_o fret_v they_o and_o the_o more_o because_o the_o fatigue_n and_o tedium_n of_o contraction_n do_v put_v they_o upon_o the_o relief_n of_o sleep_n of_o which_o if_o disappoint_v they_o be_v much_o vex_v but_o in_o the_o case_n of_o opium_n you_o can_v so_o easy_o rob_v they_o of_o their_o pleasure_n which_o they_o carry_v continual_o within_o they_o in_o a_o uninterrupted_a manner_n unless_o some_o very_a grievous_a thing_n happen_v which_o cause_v more_o defensive_a contraction_n than_o the_o opium_n cause_v relaxation_n though_o even_o this_o also_o be_v general_o soon_o overcome_v by_o the_o pleasure_n continual_o invite_v the_o relaxation_n and_o promote_a it_o whereas_o the_o interruption_n thereof_o be_v transitory_a but_o at_o the_o worst_a it_o be_v but_o take_v more_o opium_n and_o the_o work_n be_v do_v for_o i_o observe_v that_o the_o do_v of_o opium_n must_v be_v sufficient_a to_o introduce_v such_o a_o sense_n of_o pleasure_n as_o cause_v a_o relaxation_n of_o the_o contraction_n cause_v by_o the_o grievance_n hence_o it_o be_v certain_a that_o a_o great_a pain_n require_v a_o large_a do_v of_o opium_n as_o have_v be_v intimate_v 6._o all_o know_v that_o pleasant_a diversion_n as_o music_n pleasant_a jest_n and_o story_n fine_a sight_n etc._n etc._n do_v cause_n euphory_n and_o a_o easy_a undergo_n of_o journey_n labour_n etc._n etc._n therefore_o if_o such_o interrupt_v transient_a and_o slight_a pleasure_n do_v it_o so_o much_o it_o will_v be_v easy_o grant_v i_o that_o a_o continual_a and_o more_o intense_a pleasure_n that_o be_v always_o present_a without_o any_o interruption_n or_o intermission_n as_o that_o of_o opium_n must_v cause_v a_o more_o eminent_a and_o permanent_a euphory_n proportion_v to_o the_o pleasure_n which_o cause_v relaxation_n prevent_v the_o fatigue_n or_o lassitude_n that_o be_v cause_v only_o by_o contraction_n either_o vigilative_a defensive_a or_o intentive_a as_o i_o have_v prove_v so_o that_o i_o do_v not_o conceive_v how_o the_o noctambuli_n or_o such_o as_o walk_v in_o their_o sleep_n can_v ever_o be_v tire_v if_o they_o travel_v ever_o so_o far_o if_o they_o can_v eat_v and_o drink_v because_o the_o relaxation_n of_o the_o sleep_v recruit_n they_o as_o much_o as_o they_o spend_v of_o spirit_n etc._n etc._n so_o person_n that_o cause_v such_o relaxation_n by_o opium_n and_o so_o repeat_v it_o as_o to_o maintain_v the_o relaxation_n can_v hardly_o be_v weary_a which_o be_v the_o true_a plain_a and_o mechanical_a reason_n why_o the_o turk_n and_o other_o eastern_a people_n do_v by_o the_o help_n of_o opium_n perform_v prodigious_a journey_n without_o be_v tire_v which_o may_v therefore_o in_o allusion_n to_o the_o noctambuli_n be_v call_v opiambuli_n or_o opambuli_n as_o be_v a_o kind_n of_o artificial_a noctambuli_n because_o they_o be_v much_o relax_v by_o the_o pleasure_n that_o opium_n cause_n as_o the_o other_o be_v by_o sleep_n qui_fw-la laetitiâ_fw-la aâ—iciuntur_fw-la say_v sanctorius_n nuâ—lam_n in_o itinere_fw-la defatigationem_fw-la sentiunt_fw-la that_o be_v the_o merry_a be_v not_o weary_a as_o the_o say_v be_v because_o mirth_n be_v pleasant_a cause_v relaxation_n as_o opium_n do_v in_o some_o measure_n note_v that_o as_o to_o all_o the_o forego_n serene_a and_o brisk_a effect_n a_o full_a and_o liberal_a perspiration_n which_o it_o also_o cause_n as_o will_v be_v show_v contribute_v much_o thereto_o a_o posteriori_fw-la for_o as_o fire_n burn_v slow_o and_o dull_o if_o the_o smoke_n do_v by_o any_o mean_n return_v upon_o it_o and_o very_o serene_a if_o not_o so_o it_o be_v with_o the_o flame_n of_o life_n if_o cloud_v with_o or_o clear_v from_o vapour_n by_o perspiration_n sanctor_n sect._n 7._o aph._n 17._o mâ—lancholia_fw-la superatur_fw-la liberâ_fw-la perspiratione_fw-la &_o aph._n 30._o 31._o edulia_n aperientia_fw-la gaudium_fw-la movent_fw-la that_o be_v such_o as_o open_v the_o pore_n and_o cause_n perspiration_n cause_n joy_n or_o mirth_n 7._o it_o lull_v soothe_v and_o as_o it_o be_v charm_v the_o mind_n with_o consent_n and_o acquiescence_n for_o the_o several_a reason_n couch_v in_o the_o premise_n and_o because_o the_o fine_a continual_a and_o charm_a pleasure_n of_o opium_n such_o as_o some_o glass_n of_o generous_a wine_n cause_v must_v needs_o have_v such_o a_o effect_n 8._o it_o quiet_v allay_v and_o compose_v all_o perturbation_n and_o commotion_n of_o the_o sensitive_a soul_n spirit_n etc._n etc._n 1._o because_o it_o so_o lull_v soothe_v and_o charm_n the_o sensitive_a soul_n as_o be_v aforesaid_a who_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n 2._o because_o all_o motion_n be_v by_o the_o relaxation_n proportionable_o abate_v as_o be_v demonstrate_v thus_o opium_n take_v off_o hysterick_n fit_v fever_n from_o commotion_n of_o the_o spirit_n convulsion_n stop_v hemerrhage_n or_o bleed_v &c._n &c._n 9_o it_o cause_v a_o relaxation_n of_o all_o the_o sensile_a part_n of_o the_o body_n by_o reason_n of_o the_o great_a and_o continual_a pleasure_n that_o it_o cause_n and_o how_o pleasure_n cause_v relaxation_n i_o have_v show_v in_o chap._n 14._o 10._o it_o cause_v indolence_n or_o exemption_n from_o pain_n by_o cause_v so_o high_a and_o last_a a_o pleasure_n 1._o because_o that_o pleasure_n take_v up_o the_o attention_n of_o the_o sensitive_a soul_n who_o delight_v in_o it_o 2._o because_o a_o sense_n of_o pleasure_n and_o pain_n can_v be_v at_o the_o same_o time_n in_o the_o same_o subject_a be_v they_o be_v contrary_n 3._o because_o the_o membrane_n be_v relax_v and_o the_o animal_n spirit_n expanded_a the_o impression_n of_o pain_n can_v be_v carry_v to_o the_o sensitive_a soul_n because_o they_o can_v convey_v impression_n smart_o be_v thus_o relax_v and_o expanded_a as_o have_v be_v demonstrate_v by_o the_o comparison_n of_o a_o gut_n half_n full_a of_o air_n etc._n etc._n and_o all_o impression_n of_o pain_n must_v be_v smart_n or_o else_o they_o be_v not_o impression_n of_o pain_n for_o gentle_a impression_n be_v such_o as_o belong_v to_o oil_n smooth_a and_o soft_a thing_n or_o when_o the_o animal_n spirit_n can_v hardly_o carry_v any_o impression_n but_o gentle_o as_o in_o sleep_n and_o other_o relaxation_n as_o that_o upon_o pleasure_n etc._n etc._n which_o be_v our_o case_n note_v that_o it_o will_v cause_v indolence_n without_o cause_v sleep_n because_o sleep_n require_v relaxation_n and_o quiet_a of_o the_o spirit_n but_o indolence_n require_v only_a relaxation_n as_o be_v show_v which_o always_o follow_v the_o charm_a pleasure_n of_o opium_n 11._o it_o stop_v moderate_v or_o palliate_n most_o flux_n and_o promote_v perspiration_n because_o the_o relaxation_n take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o cause_v a_o contraction_n to_o squeeze_v they_o out_o and_o that_o the_o same_o relaxation_n open_v the_o pore_n to_o let_v the_o foam_n out_o which_o pass_v by_o their_o own_o levity_n upon_o the_o open_n of_o the_o pore_n nihil_fw-la magis_fw-la say_v sanctorius_n
and_o motion_n fail_v together_o of_o the_o great_a perspiration_n and_o all_o other_o effect_n of_o relaxation_n in_o such_o syncopes_fw-la or_o leipothymy_n in_o a_o yet_o high_o degree_n than_o in_o sleep_n wherein_o the_o sensitive_a soul_n do_v not_o quite_o let_v go_v the_o reign_v of_o contraction_n as_o appear_v by_o the_o motion_n that_o remain_v as_o of_o the_o heart_n intestine_n etc._n etc._n though_o far_o more_o remiss_a in_o sleep_n than_o in_o a_o wake_v state_n note_v that_o such_o leipothymy_n be_v as_o be_v hint_v of_o the_o same_o nature_n as_o sleep_n be_v but_o that_o they_o be_v sudden_a more_o profound_a and_o not_o so_o usual_a natural_a and_o of_o course_n as_o sleep_n be_v which_o make_v they_o more_o amaze_a and_o surprise_v therefore_o it_o follow_v that_o they_o be_v as_o sleep_n be_v a_o mean_n of_o recruit_v when_o all_o work_n and_o tug_v by_o defensive_a contraction_n fail_v and_o so_o the_o last_o refuge_n of_o the_o sensitive_a soul_n when_o overtired_n in_o order_n to_o recover_v strength_n for_o a_o fresh_a engagement_n with_o the_o enemy_n as_o be_v tire_v at_o night_n the_o sensitive_a soul_n loosen_v the_o rign_n of_o contraction_n to_o enable_v he_o the_o better_a to_o fall_v to_o his_o work_n the_o next_o day_n this_o you_o will_v find_v by_o all_o reason_n and_o experience_n to_o be_v the_o true_a state_n of_o leipothymy_n upon_o grievance_n and_o fatigue_n though_o not_o hitherto_o mind_v that_o i_o know_v of_o many_o true_a and_o useful_a consequence_n do_v hence_o follow_v as_o that_o we_o be_v not_o always_o to_o disturb_v they_o or_o put_v they_o out_o of_o these_o recruit_v leipothymy_n by_o grievous_a mean_n as_o pricking_n pinch_n etc._n etc._n but_o only_o by_o cordial_n and_o refresh_a thing_n as_o you_o will_v treat_v a_o person_n much_o tire_v or_o by_o let_v they_o take_v their_o nap_n if_o i_o may_v so_o call_v it_o if_o there_o be_v not_o very_o eminent_a danger_n but_o it_o be_v endless_a and_o beside_o my_o purpose_n to_o make_v a_o particular_a discourse_n of_o this_o matter_n which_o will_v belong_v more_o proper_o to_o my_o tract_n of_o animal_n mechanism_n 14._o death_n happen_v sometime_o though_o very_o rare_o and_o that_o in_o very_o weak_a people_n that_o take_v little_a or_o no_o sustenance_n because_o either_o when_o fall_v into_o such_o syncopes_fw-la they_o never_o come_v out_o of_o they_o by_o reason_n that_o they_o have_v not_o within_o they_o wherewith_o to_o recruit_v their_o spirit_n or_o that_o opium_n take_v they_o much_o spend_v and_o tire_v with_o distemper_n cause_n as_o in_o weak_a and_o weary_a people_n a_o most_o profound_a sopor_fw-la which_o not_o recruit_v they_o who_o take_v or_o digest_v no_o sustenance_n they_o must_v rather_o grow_v weak_a and_o weak_a for_o somewhat_o be_v spend_v while_o we_o live_v and_o consequent_o the_o sleep_n or_o sopor_fw-la more_o and_o more_o profound_a till_o they_o sleep_v their_o last_o for_o want_v of_o some_o recruit_v which_o be_v the_o very_a thing_n that_o natural_o lessen_v sleep_n and_o awake_v we_o when_o there_o be_v no_o other_o apparent_a cause_n for_o as_o the_o be_v tire_v and_o want_v of_o recruit_v cause_n sleep_v so_o the_o have_v it_o cause_v wake_v or_o which_o be_v the_o same_o in_o effect_n no_o far_o need_v of_o relaxation_n for_o recruit_n sake_n so_o that_o the_o sensitive_a soul_n fall_v to_o his_o useful_a work_n of_o vigilative_a contraction_n for_o sense_n and_o motion_n sake_n 15._o it_o sometime_o cause_n purge_v which_o happen_v as_o far_o as_o i_o have_v observe_v or_o can_v learn_v only_o when_o it_o be_v give_v in_o a_o good_a quantity_n to_o person_n of_o a_o strong_a digestion_n or_o canine_a appetite_n the_o case_n be_v thus_o when_o person_n that_o be_v of_o a_o strong_a digestion_n take_v a_o resinous_n opiate_n in_o good_a quantity_n they_o do_v in_o great_a measure_n by_o their_o fix_a salt_n at_o stomach_n and_o strong_a digestion_n subdue_v the_o volatility_n of_o the_o opium_n and_o dissolve_v its_o rosin_n which_o then_o as_o acrimonious_a rosin_n or_o vomit_n subdue_v by_o fix_a salt_n use_v to_o do_v cause_v purge_v hence_o it_o be_v that_o it_o general_o if_o not_o always_o purge_v dog_n and_o people_n of_o a_o high_a canine_a appetite_n and_o that_o sometime_o meet_v such_o fix_a salt_n it_o purge_v the_o consumptive_a bartholine_n say_v that_o mandrake_n juice_n purge_v when_o it_o meet_v with_o acrimonious_a fix_a salt_n erastus_n and_o quercelan_n do_v agree_v that_o it_o have_v a_o purgative_n quality_n but_o that_o it_o do_v not_o always_o exert_v it_o 1._o because_o it_o take_v away_o the_o sense_n of_o irritation_n 2._o because_o it_o be_v give_v in_o too_o small_a a_o quantity_n the_o reason_n be_v just_a and_o right_a and_o not_o only_o consistent_a with_o but_o confirm_v what_o i_o say_v note_v that_o this_o be_v not_o intend_v of_o the_o purge_v that_o happen_v after_o the_o declination_n of_o its_o operation_n which_o be_v as_o you_o will_v find_v from_o another_o cause_n therefore_o this_o do_v not_o smell_v of_o the_o opium_n as_o the_o other_o do_v because_o it_o be_v past_a and_o go_v before_o that_o in_o the_o declination_n happen_v of_o which_o more_o in_o its_o proper_a place_n 16._o it_o raise_v and_o revive_v some_o person_n that_o be_v almost_o expire_a in_o two_o case_n one_o be_v when_o such_o as_o have_v be_v use_v to_o take_v it_o be_v even_o expire_a for_o want_n of_o it_o of_o which_o more_o hereafter_o the_o other_o case_n be_v when_o violent_a contraction_n as_o from_o pain_n cold_a vomit_n and_o grievous_a passion_n as_o terror_n etc._n etc._n be_v the_o cause_n that_o people_n be_v almost_o expire_a for_o it_o take_v off_o the_o contraction_n by_o relax_v etc._n etc._n 17._o it_o stay_v very_o long_o at_o stomach_n when_o the_o rosin_n thereof_o stick_v to_o the_o stomach_n and_o be_v there_o detain_v beside_o that_o the_o stomach_n be_v relax_v and_o have_v little_a sense_n or_o motion_n as_o in_o sleep_n do_v not_o soon_o digest_v it_o or_o discharge_v it_o it_o be_v fine_a in_o this_o case_n and_o all_o other_o to_o observe_v how_o sensation_n and_o motion_n go_v hand_n in_o hand_n keep_v equal_a pace_n and_o equal_a proportion_n as_o it_o plain_o must_v be_v by_o the_o principle_n of_o relaxation_n and_o contraction_n which_o i_o have_v state_v and_o prove_v 18._o it_o cause_v stoppage_n of_o urine_n sometime_o especial_o in_o old_a people_n by_o over_o relax_v and_o cause_v a_o kind_n of_o a_o temporary_a palsy_n of_o the_o bladder_n as_o be_v show_v and_o take_v away_o the_o sense_n of_o the_o irritation_n of_o the_o urine_n which_o shall_v contract_v the_o bladder_n to_o squeeze_v it_o out_o by_o which_o mean_v it_o happen_v sometime_o that_o the_o bladder_n come_v to_o be_v so_o over_o extend_v beyond_o its_o due_a tone_n that_o they_o can_v contract_v it_o to_o make_v water_n in_o all_o which_o case_n strong_a contracter_n as_o cold_a terror_n etc._n etc._n immediate_o cure_v they_o the_o very_a put_v the_o scrotum_fw-la to_o the_o edge_n of_o a_o cold_a chamberpot_n have_v effect_v it_o several_a time_n by_o my_o advice_n though_o if_o need_v be_v you_o must_v come_v to_o dash_v of_o cold_a water_n upon_o the_o region_n of_o the_o bladder_n or_o pump_v on_o it_o or_o dip_v in_o it_o etc._n etc._n so_o terror_n and_o cause_v a_o very_a smart_n pain_n especial_o near_o those_o part_n will_v do_v much_o but_o cold_a be_v the_o ready_a and_o best_a remedy_n 19_o it_o sometime_o prove_v dangerous_a after_o great_a hemorrbage_n or_o evacuation_n as_o tapping_n in_o dropsy_n etc._n etc._n because_o the_o relaxation_n hinder_v the_o part_n due_o to_o contract_v upon_o what_o remain_v which_o may_v cause_v great_a mischief_n as_o discontinuation_n of_o motion_n etc._n etc._n thus_o have_v you_o all_o the_o constant_a frequent_a and_o rare_a effect_n of_o opium_n take_v internal_o in_o a_o moderate_a do_v so_o natural_o easy_o plain_o and_o mechanical_o explicate_v that_o people_n may_v in_o my_o judgement_n more_o admire_v how_o all_o fail_v of_o discover_v the_o manner_n of_o their_o production_n than_o that_o i_o find_v it_o as_o man_n be_v apt_a to_o think_v of_o the_o circulation_n of_o the_o blood_n which_o now_o as_o i_o hope_v the_o effect_n of_o opium_n do_v seem_v very_o obvious_a both_o which_o case_n be_v to_o i_o very_o strong_a argument_n of_o a_o be_v that_o rule_n and_o dispose_n darken_v and_o illuminate_v etc._n etc._n as_o he_o please_v when_o i_o consider_v that_o both_o the_o circulation_n of_o the_o blood_n and_o the_o cause_n of_o the_o operation_n of_o opium_n viz._n pleasure_n at_o stomach_n etc._n etc._n fall_v under_o the_o sense_n of_o many_o million_o who_o in_o one_o case_n see_v the_o blood_n move_v and_o in_o the_o other_o feel_v
which_o look_v not_o unlike_o a_o apoplexy_n make_v author_n say_v that_o opium_n cause_v apoplexy_n such_o as_o escape_v death_n do_v so_o general_o by_o 34._o plentiful_a purge_v which_o be_v occasion_v by_o a_o great_a quantity_n of_o the_o rosin_n of_o opium_n meet_v a_o strong_a digestion_n and_o fix_a salt_n as_o have_v beeâ—_n say_v 35._o sweat_v that_o smell_n of_o the_o opium_n be_v cause_v 1._o by_o the_o openness_n of_o the_o pore_n by_o relaxation_n 2._o by_o plenty_n or_o at_o least_o sufficiency_n of_o moisture_n for_o that_o end_n for_o otherwise_o as_o be_v show_v it_o will_v be_v only_o insensible_a perspiration_n 3._o by_o the_o great_a quantity_n of_o volatile_a salt_n attenuate_v the_o humour_n 4._o by_o the_o strict_a intimate_a and_o even_o indissoluble_a specific_a union_n or_o combination_n of_o the_o volatile_a salt_n and_o oily_a part_n which_o make_v it_o hold_v its_o specific_a smell_n to_o the_o last_o 36._o violent_a itch_n in_o the_o skin_n must_v of_o necessity_n follow_v a_o great_a quantity_n of_o opium_n since_o it_o cause_v such_o itch_n as_o be_v show_v in_o a_o small_a quantity_n by_o the_o titillation_n of_o its_o volatile_a salt_n note_v that_o these_o effect_n do_v not_o all_o happen_v to_o all_o man_n that_o take_v it_o in_o a_o excessive_a do_v but_o some_o to_o one_o and_o some_o to_o other_o as_o be_v intimate_v in_o chap._n 5._o according_a as_o they_o be_v more_o or_o less_o trouble_v with_o the_o rosin_n quantity_n relaxation_n etc._n etc._n chap._n xxii_o the_o explication_n of_o the_o effect_n of_o a_o long_a and_o lavish_a use_n of_o opium_n as_o a_o excessive_a do_v of_o opium_n be_v intemperance_n for_o one_o time_n so_o a_o long_a and_o lavish_a use_n of_o it_o be_v a_o habitual_a intemperance_n for_o a_o long_a time_n therefore_o if_o you_o can_v not_o rational_o expect_v good_a effâ—s_n in_o that_o case_n any_o more_o than_o from_o the_o best_a wine_n take_v sudden_o in_o a_o vast_a quantity_n it_o follow_v that_o you_o can_v expect_v good_a effect_n from_o a_o habitual_a intemperate_a take_v of_o it_o any_o more_o than_o from_o a_o long_a and_o lavish_a drink_v of_o wine_n though_o both_o be_v excellent_o good_a in_o their_o kind_a but_o that_o the_o opium_n have_v the_o pernicious_a resinous_a part_n join_v with_o it_o there_o be_v nothing_o so_o good_a whereof_o a_o intemperate_a use_n be_v not_o mischievous_a god_n have_v so_o order_v it_o to_o deter_v from_o and_o punish_v intemperance_n and_o the_o abuse_n of_o his_o creature_n therefore_o ill_a effect_n be_v not_o always_o to_o be_v impute_v to_o the_o viciousness_n of_o the_o thing_n use_v but_o frequent_o of_o the_o person_n that_o imprudent_o use_v they_o 1._o relaxation_n and_o debility_n of_o all_o part_n be_v contract_v by_o the_o habitual_a over-relaxing_a thereof_o by_o the_o lavish_a use_n of_o opium_n 2._o a_o inhability_n of_o do_v any_o thing_n without_o it_o be_v contract_v by_o the_o habitual_a pleasure_n comfort_n promptitude_n and_o euphory_n it_o cause_v when_o take_v without_o which_o the_o sensitive_a soul_n become_v lazy_a listless_a and_o averse_a to_o all_o action_n it_o be_v as_o iâ—_n a_o man_n use_v to_o dance_n to_o excellent_a music_n be_v require_v to_o do_v it_o without_o any_o music_n at_o all_o nor_o as_o much_o as_o thought_n of_o it_o or_o mumble_v it_o within_o himself_o or_o that_o one_o who_o drink_v nothing_o but_o wine_n and_o eat_v the_o best_a shall_v be_v sudden_o deny_v both_o and_o force_v to_o live_v upon_o bread_n and_o water_n or_o that_o such_o as_o always_o take_v tobacco_n at_o their_o study_n shall_v be_v sudden_o debar_v thereof_o and_o require_v to_o study_v without_o it_o how_o very_o listless_a will_v a_o man_n be_v in_o such_o case_n though_o hardly_o any_o of_o the_o comparison_n come_v up_o to_o that_o of_o opium_n because_o of_o the_o charm_a pleasure_n mighty_a euphory_n and_o promptitude_n that_o it_o cause_n it_o be_v as_o if_o one_o be_v support_v and_o whole_o depend_v upon_o cordial_n and_o sudden_o deny_v they_o etc._n etc._n 3._o a_o inhability_n of_o get_v up_o in_o the_o morning_n till_o it_o be_v take_v and_o begin_v to_o operate_v proceed_v from_o the_o same_o cause_n a_o mechanical_a reason_n may_v be_v expect_v here_o also_o as_o to_o these_o matter_n but_o it_o will_v hardly_o bear_v it_o any_o more_o than_o how_o the_o will_n or_o appetite_n cause_v the_o first_o impulse_n towards_o voluntary_a moti_fw-la n_o all_o that_o can_v be_v say_v be_v that_o without_o the_o opium_n the_o sensitive_a soul_n be_v when_o he_o do_v any_o thing_n to_o act_v under_o the_o toil_n and_o difficulty_n of_o a_o full_a vigilative_a contraction_n as_o be_v awake_a intentive_a contraction_n as_o act_v and_o defensive_a contraction_n as_o be_v grieve_v when_o the_o operation_n of_o opium_n be_v over_o as_o after_o veneral_a pleasure_n etc._n etc._n so_o that_o now_o he_o labour_v under_o the_o great_a disadvantage_n and_o drudgery_n of_o all_o the_o three_o contraction_n whereas_o by_o the_o pleasure_n fine_a titillation_n of_o opium_n and_o relaxation_n consequential_a thereunto_o he_o be_v ease_v of_o all_o the_o defensive_a contraction_n which_o be_v the_o most_o grievous_a and_o in_o great_a measure_n of_o the_o vigilative_a as_o have_v be_v show_v which_o make_v work_v journey_a etc._n etc._n very_o easy_a to_o he_o therefore_o it_o be_v as_o if_o one_o that_o delight_v in_o music_n dance_v to_o charm_a melody_n in_o belove_a company_n with_o please_a refection_n of_o wine_n etc._n etc._n and_o in_o the_o other_o case_n as_o if_o one_o labour_v in_o grief_n or_o pain_n now_o suppose_v that_o one_o use_v never_o to_o act_n or_o work_n without_o such_o mighty_a pleasant_a advantage_n and_o cause_n of_o euphory_n be_v require_v to_o act_v under_o the_o pressure_n of_o the_o three_o contraction_n or_o in_o grief_n or_o pain_n how_o listless_a will_v he_o be_v to_o act_n work_n get_v up_o etc._n etc._n 4._o a_o dull_a moapish_a and_o heavy_a disposition_n must_v be_v the_o effect_n unless_o it_o be_v while_o they_o please_v comfort_n and_o enliven_v themselves_o by_o the_o opium_n because_o their_o brain_n be_v habitual_o over_o relax_v which_o be_v the_o very_a case_n of_o old_a drunkard_n who_o have_v as_o it_o be_v say_v drink_v away_o their_o part_n by_o such_o a_o habitual_a relaxation_n of_o the_o brain_n which_o overmuch_o sleep_v cause_n also_o upon_o the_o account_n of_o the_o like_a relaxation_n therefore_o they_o must_v be_v moapish_a till_o the_o please_a titillation_n of_o opium_n enlivens_fw-la they_o 5._o diminution_n of_o appetite_n be_v cause_v by_o a_o habitual_a relaxation_n of_o the_o stomach_n take_v away_o its_o sensation_n and_o suspend_v the_o menstruum_fw-la from_o flow_v to_o it_o as_o free_o as_o it_o shall_v and_o will_v if_o there_o be_v a_o due_a contraction_n to_o squeeze_v it_o out_o 6._o weakness_n of_o digestion_n happen_v from_o the_o same_o cause_n 7._o dropsy_n be_v cause_v by_o the_o relaxation_n weaken_v the_o part_n and_o make_v they_o thereby_o susceptible_a of_o humour_n as_o also_o by_o diminution_n of_o appetite_n and_o digestion_n as_o in_o old_a drunkard_n 8._o decay_n of_o part_n or_o wit_n happen_v from_o habitual_a relaxation_n of_o the_o brain_n and_o its_o membrane_n as_o in_o old_a drunkard_n 9_o weakness_n of_o memory_n proceed_v from_o the_o same_o cause_n as_o in_o old_a drunkard_n 10._o stoop_v in_o the_o back_n be_v cause_v by_o the_o habitual_a relaxation_n of_o the_o part_n which_o weaken_v and_o cause_v they_o to_o comply_v with_o our_o tendency_n and_o use_v of_o bend_v forward_o and_o yield_v to_o the_o great_a weight_n that_o be_v general_o speak_v on_o the_o foreside_n of_o the_o backbone_n or_o perpendicular_a so_o that_o stoop_v must_v gradual_o follow_v those_o conspire_a cause_n as_o it_o do_v in_o habitual_a drunkard_n who_o part_n be_v relax_v 11._o early_o decrepiteness_n must_v proceed_v from_o the_o aforesaid_a relaxation_n spoil_v the_o tone_n of_o part_n and_o cause_v want_n of_o appetite_n digestion_n etc._n etc._n in_o the_o manner_n before_o show_v 12._o shortness_n of_o life_n must_v be_v the_o effect_n of_o the_o same_o cause_n 13._o acrimony_n of_o blood_n proceed_v from_o the_o abundance_n of_o acrimonious_a volatile_a salt_n take_v in_o the_o opium_n wherein_o it_o be_v much_o more_o acrimonious_a than_o our_o natural_a volatile_a salt_n and_o in_o great_a quantity_n proportionable_o therefore_o it_o can_v be_v no_o wonder_n that_o 14._o it_o excite_v inclination_n to_o venery_n by_o that_o acrimonious_a salt_n which_o be_v analogous_a to_o that_o of_o cantharides_n aunt_n bee_n etc._n etc._n 15._o frequent_a inclination_n to_o make_v water_n be_v also_o a_o know_a and_o common_a effect_n of_o such_o a_o salt_n by_o its_o irritate_v and_o solicit_v the_o bladder_n etc._n etc._n 16._o priapism_n