sleep_v be_v the_o sound_a and_o that_o sleep_v gradual_o decline_v in_o degree_n as_o we_o be_v recruit_v till_o we_o awake_v the_o near_a which_o we_o be_v the_o more_o we_o dream_v the_o state_n of_o dream_v be_v a_o kind_n of_o twilight_n between_o sound_a sleep_n and_o awake_v or_o between_o a_o full_a somniferous_a relaxation_n and_o vigilative_a contraction_n and_o as_o the_o sensitive_a soul_n use_v all_o degree_n of_o contraction_n below_o that_o of_o the_o vigilative_a till_o it_o come_v to_o bare_a compression_n of_o the_o air_n so_o it_o can_v exercise_v super-vigilative_a contraction_n if_o i_o may_v so_o call_v it_o that_o be_v much_o high_a degree_n thereof_o than_o what_o be_v requisite_a ordinary_o for_o a_o state_n of_o vigilancy_n as_o in_o case_n of_o danger_n to_o the_o animal_n fright_v terror_n grievous_a passion_n and_o sensation_n by_o which_o mean_v the_o animal_n spirit_n be_v more_o compress_v than_o under_o the_o ordinary_a vigilative_a contraction_n sensation_n grow_v more_o nice_a and_o smart_a and_o motion_n more_o prompt_a and_o vigorous_a they_o always_o go_v together_o for_o the_o defence_n of_o the_o animal_n by_o extraordinary_a flight_n repulsion_n or_o otherwise_o hence_o it_o be_v upon_o fear_n terror_n grievous_a passion_n or_o sensation_n which_o manifest_o prove_v the_o be_v of_o such_o a_o extraordinary_a contraction_n upon_o such_o occasion_n that_o 1._o perspiration_n sail_v in_o a_o yet_o high_o degree_n than_o under_o bare_a or_o ordinary_a vigilative_a contraction_n as_o appear_v by_o infallible_a statick_a experiment_n and_o demonstration_n 2._o it_o be_v by_o reason_n of_o the_o say_v defensive_a contraction_n for_o so_o i_o call_v it_o because_o it_o be_v excite_v in_o a_o extraordinary_a manner_n for_o the_o defence_n of_o the_o animal_n in_o time_n of_o need_n or_o great_a exigence_n that_o in_o fright_v terror_n etc._n etc._n our_o hair_n dog_n etc._n etc._n do_v stand_v on_o end_n or_o more_o upright_o 1._o because_o the_o pore_n do_v by_o that_o violent_a contraction_n strict_o close_a about_o the_o root_n of_o the_o hair_n that_o it_o can_v swag_v incline_v or_o yield_v any_o way_n by_o reason_n of_o its_o weight_n etc._n etc._n as_o when_o the_o skin_n be_v more_o lax_n and_o soft_a and_o the_o pore_n wherein_o the_o hair_n be_v fix_v more_o open_a 2._o because_o which_o be_v the_o main_a reason_n the_o say_a contraction_n render_v the_o oblique_a pore_n more_o upright_o as_o suppose_v the_o pore_n and_o hair_n do_v natural_o stand_v oblique_o as_o they_o do_v to_o carry_v off_o wet_a etc._n etc._n as_o in_o fig._n 1._o fig_n i_o fig_n two_o and_o that_o a_o in_o fig._n 1._o be_v by_o the_o say_a contraction_n bring_v near_a to_o ay_o as_o much_o as_o be_v from_o a_o to_o o_o then_o will_v the_o pore_n and_o hair_n stand_v upright_o as_o in_o fig._n 2._o and_o the_o skin_n a_o o_o e_o i_o s_o contract_v and_o bring_v within_o the_o prick_v perpendicular_o whereas_o in_o fig._n 1._o it_o excure_v beyond_o the_o perpendicular_a n_z m_z as_o much_o as_o be_v from_o a_o to_o o._n 3._o for_o the_o same_o reason_n it_o be_v that_o the_o face_n in_o grievous_a passion_n and_o sensation_n as_o acute_a pain_n etc._n etc._n be_v contort_a and_o wring_v awry_o as_o you_o see_v in_o person_n that_o cry_v because_o of_o grievance_n after_o the_o same_o manner_n as_o when_o they_o strive_v to_o lift_v up_o a_o great_a weight_n and_o that_o at_o the_o same_o time_n tear_n and_o moisture_n at_o nose_n and_o mouth_n be_v squeeze_v out_o by_o the_o same_o contraction_n which_o make_v people_n use_v the_o say_v of_o casting_n snot_n about_o when_o man_n cry_v it_o be_v for_o the_o same_o reason_n that_o people_n mouth_n water_n extreme_o when_o they_o be_v trim_v with_o a_o bad_a razor_n that_o put_v they_o to_o pain_n which_o contract_v the_o part_n and_o squeeze_v out_o the_o spital_n 4._o the_o pulse_n grow_v sensible_o narrow_a and_o hard_a by_o the_o same_o contraction_n 5._o it_o be_v by_o the_o contraction_n upon_o grievous_a sensation_n that_o our_o mouth_n water_n very_o much_o upon_o a_o nausea_n at_o stomach_n because_o of_o the_o continuity_n of_o the_o membrane_n of_o the_o mouth_n and_o stomach_n 6._o the_o same_o contraction_n be_v the_o true_a reason_n why_o people_n upon_o hunger_n which_o be_v a_o grievous_a sensation_n at_o stomach_n have_v so_o much_o moisture_n or_o spital_n in_o their_o mouth_n and_o so_o much_o the_o more_o when_o they_o see_v good_a victual_n and_o can_v have_v it_o because_o the_o grievance_n which_o cause_v the_o contraction_n that_o squeeze_v it_o out_o be_v by_o so_o much_o the_o great_a this_o be_v the_o cause_n why_o the_o mouth_n water_n when_o hungry_a people_n see_v or_o smell_v good_a victual_n by_o the_o same_o contraction_n moisture_n be_v squeeze_v out_o into_o the_o oesophagus_n or_o gullet_n and_o the_o menstruum_fw-la into_o the_o stomach_n at_o the_o same_o time_n where_o observe_v god_n good_a and_o wise_a providence_n that_o hunger_n which_o call_v for_o meat_n at_o the_o same_o time_n provide_v spital_n to_o lubricate_v it_o for_o swollow_v and_o to_o help_v digestion_n render_v the_o gullet_n slippery_a and_o distensible_a and_o cause_v the_o menstruum_fw-la to_o flow_v more_o abundant_o into_o the_o stomach_n and_o all_o this_o when_o most_o need_v and_o that_o exact_o in_o proportion_n to_o the_o hunger_n or_o grievous_a sensation_n that_o cause_v the_o contraction_n it_o be_v well_o worth_a your_o nothing_o that_o god_n wisdom_n do_v always_o cause_v the_o want_n of_o what_o be_v necessary_a in_o sensile_a creature_n to_o be_v the_o solicit_v and_o urge_v cause_n for_o supply_v that_o a_o due_a proportion_n may_v be_v observe_v between_o the_o supply_n and_o the_o want_n which_o may_v upon_o the_o tell_n of_o it_o appear_v so_o plain_a a_o case_n that_o it_o be_v scarce_o worth_a the_o mention_v but_o believe_v i_o it_o be_v so_o little_o observe_v as_o plain_a as_o it_o may_v seem_v to_o be_v that_o people_n have_v and_o do_v err_v extravagant_o for_o want_n of_o note_v it_o which_o if_o they_o have_v note_v they_o can_v never_o have_v say_v that_o vapour_n or_o the_o retire_n of_o spirit_n into_o the_o brain_n etc._n etc._n be_v the_o cause_n or_o call_v of_o natural_a sleep_n nor_o feign_v menstruum_n to_o be_v the_o cause_n of_o hunger_n but_o will_v have_v due_o consider_v what_o be_v main_o supply_v by_o eat_v or_o recruit_v by_o sleep_v etc._n etc._n and_o then_o have_v nothing_o to_o do_v but_o to_o conclude_v the_o defect_n of_o that_o to_o have_v be_v the_o cause_n that_o solicit_v for_o the_o supply_n in_o proportion_n to_o the_o defect_n which_o if_o observe_v will_v most_o natural_o and_o easy_o lead_v you_o to_o the_o true_a knowledge_n of_o the_o cause_n of_o all_o appetite_n in_o a_o animal_n upon_o a_o few_o minute_n consideration_n for_o want_v of_o which_o most_o plain_a and_o one_o will_v think_v very_o obvious_a method_n the_o deviate_a world_n have_v sad_o puzzle_v itself_o about_o the_o cause_n of_o hunger_n thirst_v sleep_v and_o the_o like_a to_o this_o day_n and_o still_o be_v in_o dispute_n about_o they_o of_o which_o though_o my_o advertent_fw-la reader_n may_v well_o prevent_v i_o by_o use_v that_o natural_a method_n i_o shall_v god_n will_v give_v a_o account_n in_o my_o tract_n of_o animal_n mechanism_n only_a note_n here_o that_o i_o do_v not_o mean_v bare_a privative_a defect_n as_o such_o to_o be_v the_o positive_a cause_n but_o that_o the_o defect_n of_o what_o keep_v or_o guard_v the_o stomach_n etc._n etc._n from_o the_o grievance_n cause_v other_o matter_n to_o grieve_v it_o cause_n hunger_n etc._n etc._n without_o which_o mean_n no_o proportion_n can_v be_v observe_v between_o hunger_n and_o what_o take_v it_o away_o or_o our_o food_n 7._o the_o same_o defensive_a contraction_n do_v upon_o grievous_a sensation_n as_o pain_n cold_a terror_n etc._n etc._n cause_n a_o corrugation_n of_o the_o scrotum_fw-la contract_v the_o skin_n into_o little_a tubercle_n like_o that_o of_o a_o goose-skin_n etc._n etc._n 8._o by_o it_o upon_o grievous_a sensation_n as_o by_o squeeze_v the_o nose_n very_o hard_o pull_v the_o hair_n sand_n or_o any_o such_o thing_n in_o the_o eye_n or_o a_o grievance_n by_o the_o volatile_a particle_n of_o onion_n mustard_n horse-radish-root_n etc._n etc._n the_o part_n and_o membrane_n about_o the_o eye_n contract_v squeeze_v out_o tear_n that_o what_o grieve_v the_o eye_n may_v thereby_o be_v wash_v away_o or_o qualify_v as_o much_o as_o the_o tear_n can_v do_v it_o 9_o by_o this_o contraction_n repel_v the_o blood_n the_o skin_n grow_v pale_a by_o cold_a fear_v pain_n etc._n etc._n which_o also_o close_v the_o pore_n stop_v sweat_n as_o in_o a_o moment_n you_o will_v have_v a_o account_n hereafter_o how_o contraction_n may_v cause_v sweat_n
only_o in_o those_o membrane_n but_o also_o in_o the_o more_o exquisite_o dispose_v membrane_n for_o sensation_n at_o stomach_n and_o soon_o after_o all_o over_o the_o body_n 5._o it_o prevent_v and_o take_v away_o grief_n fear_v anxiety_n peevishness_n fretfulness_n etc._n etc._n for_o the_o aforesaid_a reason_n which_o cause_n a_o blithe_a gay_a and_o good_a humour_n promptitude_n courage_n etc._n etc._n for_o it_o be_v impossible_a to_o be_v gay_a and_o good_a humour_a serene_a cheerful_a courageous_a and_o magnanimous_a and_o at_o the_o same_o time_n sorrowful_a fearful_a peevish_a fretful_a etc._n etc._n if_o the_o bare_a sense_n of_o a_o ordinary_a meal_n of_o meat_n at_o stomach_n which_o cause_v but_o a_o slow_a pleasure_n in_o comparison_n with_o opium_n take_v off_o the_o peevishness_n fretfulness_n etc._n etc._n that_o the_o grievous_a sensation_n of_o hunger_n cause_n how_o much_o more_o must_v the_o intense_a and_o charm_a pleasure_n cause_v by_o opium_n that_o be_v so_o agreeable_a even_o far_o beyond_o wine_n itself_o as_o have_v be_v set_v forth_o take_v away_o all_o ill_a humour_n fretfulness_n peevishness_n etc._n etc._n obj._n but_o it_o may_v be_v say_v that_o sleepiness_n which_o depend_v also_o upon_o relaxation_n as_o the_o effect_n of_o pleasure_n do_v cause_v a_o peevish_a fretful_a humour_n as_o be_v common_o observe_v ans._n it_o be_v so_o far_o otherwise_o in_o the_o case_n of_o opium_n that_o it_o be_v quite_o contrary_a for_o 1._o the_o sleepy_a be_v not_o peevish_a unless_o you_o put_v they_o by_o some_o mean_v out_o of_o the_o pleasure_n of_o enjoy_v sleep_n or_o relaxation_n for_o if_o you_o let_v they_o alone_o they_o will_v not_o trouble_v you_o with_o peevishness_n nor_o any_o ill_a humour_n but_o it_o be_v the_o call_v they_o from_o their_o relaxed_a condition_n to_o the_o grievous_a task_n of_o contraction_n that_o vex_v they_o so_o that_o it_o be_v the_o want_n of_o continue_v under_o the_o relaxation_n that_o fret_v they_o and_o the_o more_o because_o the_o fatigue_n and_o tedium_n of_o contraction_n do_v put_v they_o upon_o the_o relief_n of_o sleep_n of_o which_o if_o disappoint_v they_o be_v much_o vex_v but_o in_o the_o case_n of_o opium_n you_o can_v so_o easy_o rob_v they_o of_o their_o pleasure_n which_o they_o carry_v continual_o within_o they_o in_o a_o uninterrupted_a manner_n unless_o some_o very_a grievous_a thing_n happen_v which_o cause_v more_o defensive_a contraction_n than_o the_o opium_n cause_v relaxation_n though_o even_o this_o also_o be_v general_o soon_o overcome_v by_o the_o pleasure_n continual_o invite_v the_o relaxation_n and_o promote_a it_o whereas_o the_o interruption_n thereof_o be_v transitory_a but_o at_o the_o worst_a it_o be_v but_o take_v more_o opium_n and_o the_o work_n be_v do_v for_o i_o observe_v that_o the_o do_v of_o opium_n must_v be_v sufficient_a to_o introduce_v such_o a_o sense_n of_o pleasure_n as_o cause_v a_o relaxation_n of_o the_o contraction_n cause_v by_o the_o grievance_n hence_o it_o be_v certain_a that_o a_o great_a pain_n require_v a_o large_a do_v of_o opium_n as_o have_v be_v intimate_v 6._o all_o know_v that_o pleasant_a diversion_n as_o music_n pleasant_a jest_n and_o story_n fine_a sight_n etc._n etc._n do_v cause_n euphory_n and_o a_o easy_a undergo_n of_o journey_n labour_n etc._n etc._n therefore_o if_o such_o interrupt_v transient_a and_o slight_a pleasure_n do_v it_o so_o much_o it_o will_v be_v easy_o grant_v i_o that_o a_o continual_a and_o more_o intense_a pleasure_n that_o be_v always_o present_a without_o any_o interruption_n or_o intermission_n as_o that_o of_o opium_n must_v cause_v a_o more_o eminent_a and_o permanent_a euphory_n proportion_v to_o the_o pleasure_n which_o cause_v relaxation_n prevent_v the_o fatigue_n or_o lassitude_n that_o be_v cause_v only_o by_o contraction_n either_o vigilative_a defensive_a or_o intentive_a as_o i_o have_v prove_v so_o that_o i_o do_v not_o conceive_v how_o the_o noctambuli_n or_o such_o as_o walk_v in_o their_o sleep_n can_v ever_o be_v tire_v if_o they_o travel_v ever_o so_o far_o if_o they_o can_v eat_v and_o drink_v because_o the_o relaxation_n of_o the_o sleep_v recruit_n they_o as_o much_o as_o they_o spend_v of_o spirit_n etc._n etc._n so_o person_n that_o cause_v such_o relaxation_n by_o opium_n and_o so_o repeat_v it_o as_o to_o maintain_v the_o relaxation_n can_v hardly_o be_v weary_a which_o be_v the_o true_a plain_a and_o mechanical_a reason_n why_o the_o turk_n and_o other_o eastern_a people_n do_v by_o the_o help_n of_o opium_n perform_v prodigious_a journey_n without_o be_v tire_v which_o may_v therefore_o in_o allusion_n to_o the_o noctambuli_n be_v call_v opiambuli_n or_o opambuli_n as_o be_v a_o kind_n of_o artificial_a noctambuli_n because_o they_o be_v much_o relax_v by_o the_o pleasure_n that_o opium_n cause_n as_o the_o other_o be_v by_o sleep_n qui_fw-la laetitiâ_fw-la aâ—iciuntur_fw-la say_v sanctorius_n nuâ—lam_n in_o itinere_fw-la defatigationem_fw-la sentiunt_fw-la that_o be_v the_o merry_a be_v not_o weary_a as_o the_o say_v be_v because_o mirth_n be_v pleasant_a cause_v relaxation_n as_o opium_n do_v in_o some_o measure_n note_v that_o as_o to_o all_o the_o forego_n serene_a and_o brisk_a effect_n a_o full_a and_o liberal_a perspiration_n which_o it_o also_o cause_n as_o will_v be_v show_v contribute_v much_o thereto_o a_o posteriori_fw-la for_o as_o fire_n burn_v slow_o and_o dull_o if_o the_o smoke_n do_v by_o any_o mean_n return_v upon_o it_o and_o very_o serene_a if_o not_o so_o it_o be_v with_o the_o flame_n of_o life_n if_o cloud_v with_o or_o clear_v from_o vapour_n by_o perspiration_n sanctor_n sect._n 7._o aph._n 17._o mâ—lancholia_fw-la superatur_fw-la liberâ_fw-la perspiratione_fw-la &_o aph._n 30._o 31._o edulia_n aperientia_fw-la gaudium_fw-la movent_fw-la that_o be_v such_o as_o open_v the_o pore_n and_o cause_n perspiration_n cause_n joy_n or_o mirth_n 7._o it_o lull_v soothe_v and_o as_o it_o be_v charm_v the_o mind_n with_o consent_n and_o acquiescence_n for_o the_o several_a reason_n couch_v in_o the_o premise_n and_o because_o the_o fine_a continual_a and_o charm_a pleasure_n of_o opium_n such_o as_o some_o glass_n of_o generous_a wine_n cause_v must_v needs_o have_v such_o a_o effect_n 8._o it_o quiet_v allay_v and_o compose_v all_o perturbation_n and_o commotion_n of_o the_o sensitive_a soul_n spirit_n etc._n etc._n 1._o because_o it_o so_o lull_v soothe_v and_o charm_n the_o sensitive_a soul_n as_o be_v aforesaid_a who_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n 2._o because_o all_o motion_n be_v by_o the_o relaxation_n proportionable_o abate_v as_o be_v demonstrate_v thus_o opium_n take_v off_o hysterick_n fit_v fever_n from_o commotion_n of_o the_o spirit_n convulsion_n stop_v hemerrhage_n or_o bleed_v &c._n &c._n 9_o it_o cause_v a_o relaxation_n of_o all_o the_o sensile_a part_n of_o the_o body_n by_o reason_n of_o the_o great_a and_o continual_a pleasure_n that_o it_o cause_n and_o how_o pleasure_n cause_v relaxation_n i_o have_v show_v in_o chap._n 14._o 10._o it_o cause_v indolence_n or_o exemption_n from_o pain_n by_o cause_v so_o high_a and_o last_a a_o pleasure_n 1._o because_o that_o pleasure_n take_v up_o the_o attention_n of_o the_o sensitive_a soul_n who_o delight_v in_o it_o 2._o because_o a_o sense_n of_o pleasure_n and_o pain_n can_v be_v at_o the_o same_o time_n in_o the_o same_o subject_a be_v they_o be_v contrary_n 3._o because_o the_o membrane_n be_v relax_v and_o the_o animal_n spirit_n expanded_a the_o impression_n of_o pain_n can_v be_v carry_v to_o the_o sensitive_a soul_n because_o they_o can_v convey_v impression_n smart_o be_v thus_o relax_v and_o expanded_a as_o have_v be_v demonstrate_v by_o the_o comparison_n of_o a_o gut_n half_n full_a of_o air_n etc._n etc._n and_o all_o impression_n of_o pain_n must_v be_v smart_n or_o else_o they_o be_v not_o impression_n of_o pain_n for_o gentle_a impression_n be_v such_o as_o belong_v to_o oil_n smooth_a and_o soft_a thing_n or_o when_o the_o animal_n spirit_n can_v hardly_o carry_v any_o impression_n but_o gentle_o as_o in_o sleep_n and_o other_o relaxation_n as_o that_o upon_o pleasure_n etc._n etc._n which_o be_v our_o case_n note_v that_o it_o will_v cause_v indolence_n without_o cause_v sleep_n because_o sleep_n require_v relaxation_n and_o quiet_a of_o the_o spirit_n but_o indolence_n require_v only_a relaxation_n as_o be_v show_v which_o always_o follow_v the_o charm_a pleasure_n of_o opium_n 11._o it_o stop_v moderate_v or_o palliate_n most_o flux_n and_o promote_v perspiration_n because_o the_o relaxation_n take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o cause_v a_o contraction_n to_o squeeze_v they_o out_o and_o that_o the_o same_o relaxation_n open_v the_o pore_n to_o let_v the_o foam_n out_o which_o pass_v by_o their_o own_o levity_n upon_o the_o open_n of_o the_o pore_n nihil_fw-la magis_fw-la say_v sanctorius_n
best_a part_n of_o opium_n which_o be_v so_o much_o the_o better_a the_o more_o it_o abound_v with_o they_o 9_o if_o it_o yield_v any_o other_o tincture_n than_o red_a it_o be_v not_o right_a and_o the_o dull_a or_o pale_a the_o red_a be_v the_o worse_a or_o weak_a it_o be_v 10._o the_o best_a be_v heavy_a in_o proportion_n to_o its_o bulk_n which_o you_o may_v soon_o experiment_n thus_o weigh_v a_o ounce_n of_o each_o in_o the_o air_n then_o weigh_v they_o just_a as_o they_o be_v in_o the_o brass_n scales_n in_o water_n and_o the_o heavy_a will_n outweigh_v the_o other_o in_o water_n for_o the_o heavy_a any_o thing_n be_v the_o less_o water_n take_v from_o its_o weight_n in_o proportion_n to_o its_o bulk_n this_o be_v a_o infallible_a and_o most_o ready_a way_n to_o know_v the_o weight_n of_o any_o thing_n in_o proportion_n to_o its_o bulk_n note_v that_o my_o discourse_n be_v most_o particular_o concern_v the_o best_a sort_n of_o crude_a turkey_n opium_n that_o be_v the_o best_a that_o we_o have_v in_o common_a use_n and_o that_o its_o effect_n and_o not_o those_o of_o any_o preparation_n thereof_o be_v set_v down_o in_o the_o follow_a chapter_n chap_n iii_o the_o effect_n of_o opium_n use_v external_o opium_n use_v external_o have_v two_o sort_n of_o effect_n upon_o a_o humane_a body_n 1._o as_o a_o opiate_n to_o cause_n sleep_n take_v away_o pain_n etc._n etc._n 2._o as_o a_o alterative_a of_o the_o part_n it_o be_v apply_v to_o i._o as_o a_o opiate_n it_o be_v of_o very_o uncertain_a and_o uneven_a effect_n when_o apply_v external_o for_o sometime_o it_o cause_v sleep_n take_v away_o pain_n but_o it_o often_o fail_v therefore_o it_o be_v general_o much_o better_a safe_a more_o certain_a and_o effectual_a to_o use_v it_o internal_o i_o do_v scarce_o know_v the_o case_n wherein_o it_o be_v better_a to_o use_v it_o external_o than_o internal_o unless_o it_o be_v to_o smell_v to_o in_o some_o case_n but_o of_o these_o thing_n more_o particular_o when_o we_o come_v to_o the_o use_v of_o opium_n in_o cure_v prevent_v or_o paliate_a disease_n for_o here_o we_o only_o lie_v down_o effect_n in_o order_n to_o a_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n to_o which_o its_o internal_a effect_n will_v main_o contribute_v however_o it_o may_v be_v very_o useful_a to_o that_o end_n to_o lay_v down_o its_o alterative_a effect_n for_o thereby_o we_o shall_v in_o good_a measure_n know_v the_o prin_fw-mi ciple_n by_o which_o it_o operate_v ii_o it_o be_v external_a effect_n as_o a_o alterative_a be_v these_o viz._n 1._o it_o incides_fw-la resolve_n and_o discuss_n 2._o it_o relax_n and_o mollify_v 3._o it_o maturate_v and_o suppurate_v 4._o it_o exulcerate_v or_o cause_n blister_n if_o it_o be_v very_o strong_a and_o apply_v to_o person_n of_o a_o fine_a texture_n where_o the_o skin_n be_v tender_a but_o this_o effect_n belong_v more_o proper_o to_o the_o maslack_n or_o true_a 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o drop_n from_o the_o incision_n make_v in_o the_o head_n of_o the_o poppy_n especial_o the_o theban_a which_o afford_v a_o very_a powerful_a juice_n hence_o you_o may_v observe_v that_o the_o more_o it_o exulcerates_n or_o blister_n the_o better_a be_v the_o opium_n &_o vice_fw-la versâ_fw-la 5._o it_o be_v a_o psilotherick_n for_o it_o prevent_v hair_n to_o grow_v and_o cause_v the_o shed_v thereof_o 6._o it_o be_v hurtful_a to_o the_o eye_n and_o ear_n 7._o it_o excite_v itch_n apply_v in_o a_o moderate_a manner_n to_o the_o skin_n 8._o it_o excite_v venery_n apply_v to_o the_o perinaeum_n chap._n iu._n the_o effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o the_o moderate_a do_v in_o ordinary_a use_n to_o produce_v the_o follow_a effect_n be_v from_o one_o to_o three_o grain_n more_o or_o less_o according_a to_o the_o circumstance_n condition_n case_n constitution_n age_n &c_n &c_n of_o the_o person_n who_o take_v it_o 2._o it_o operate_v general_o in_o a_o short_a time_n after_o it_o be_v in_o the_o stomach_n that_o be_v in_o about_o half_a a_o hour_n more_o or_o less_o if_o take_v in_o a_o liquid_a form_n and_o in_o about_o a_o hour_n more_o or_o less_o if_o in_o a_o solid_a form_n drink_v a_o draught_n of_o water_n or_o some_o liquor_n after_o it_o otherwise_o it_o may_v be_v sometime_o near_o a_o hour_n and_o a_o half_a before_o it_o have_v its_o full_a effect_n but_o the_o time_n of_o its_o operation_n have_v a_o considerable_a latitude_n according_a to_o the_o disposition_n of_o the_o stomach_n and_o other_o circumstance_n as_o the_o vehicle_n it_o be_v take_v in_o etc._n etc._n the_o constant_a effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o diffuse_v itself_o in_o a_o kind_n of_o indefinite_a manner_n seizing_z one_o not_o unlike_o the_o gentle_a sweet_a deliquium_fw-la that_o we_o find_v upon_o our_o entrance_n into_o a_o most_o agreeable_a slumber_n which_o upon_o yield_v to_o it_o general_o end_v in_o sleep_n but_o if_o the_o person_n keep_v himself_o in_o action_n discourse_n or_o business_n it_o seem_v especial_o when_o give_v in_o a_o mornning_a after_o a_o moderate_a rest_n at_o night_n like_o a_o most_o delicious_a and_o extraordinary_a refreshment_n of_o the_o spirit_n upon_o very_o good_a news_n or_o any_o other_o great_a cause_n of_o joy_n as_o the_o sight_n of_o a_o dear_o belove_a person_n etc._n etc._n thought_n to_o have_v be_v lose_v at_o sea_n or_o the_o like_a cause_v such_o a_o pleasant_a ovation_n of_o the_o spirit_n serenity_n etc._n etc._n as_o we_o find_v after_o a_o competent_a measure_n of_o generous_a wine_n ad_fw-la hilaritatem_fw-la as_o man_n use_v to_o say_v it_o be_v indeed_o so_o unexpressible_o fine_a and_o sweet_a a_o pleasure_n that_o it_o be_v very_o difficult_a for_o i_o to_o describe_v or_o any_o to_o conceive_v it_o but_o such_o as_o actual_o feel_v it_o for_o it_o be_v as_o if_o a_o good_a genius_n possess_v or_o inform_v a_o man_n therefore_o people_n do_v common_o call_v it_o a_o heavenly_a condition_n as_o if_o no_o worldly_a pleasure_n be_v to_o be_v compare_v with_o it_o helmontianus_fw-la will_v doubtless_o express_v it_o by_o the_o archaeus_n in_o his_o very_a best_a humour_n it_o have_v be_v compare_v not_o without_o good_a cause_n to_o a_o permanent_a gentle_a degree_n of_o that_o pleasure_n which_o modesty_n forbid_v the_o name_n of_o and_o it_o be_v well_o worth_a a_o remark_n that_o both_o be_v pleasure_n of_o the_o same_o sense_n viz._n that_o of_o feel_v for_o it_o can_v be_v a_o pleasure_n of_o any_o other_o sense_n since_o it_o be_v internal_a 2._o it_o cause_v a_o brisk_a gay_a and_o good_a humour_n nor_o do_v i_o doubt_v but_o it_o have_v this_o effect_n upon_o sleep_a person_n as_o far_o as_o their_o condition_n be_v capable_a of_o observe_v it_o for_o you_o shall_v have_v they_o often_o tell_v of_o pleasant_a dream_n after_o it_o when_o they_o remember_v they_o and_o speak_v of_o any_o see_v bauchin_n and_o the_o author_n mention_v below_o under_o the_o four_o effect_n of_o opium_n 3._o it_o cause_v promptitude_n serenity_n alacrity_n and_o expediteness_n in_o dispatch_v and_o manage_n of_o business_n to_o which_o end_n and_o that_o of_o a_o good_a and_o gay_a humour_n which_o be_v near_o of_o kind_n it_o be_v common_o take_v in_o the_o morning_n in_o the_o eastern_a country_n with_o most_o certain_a effect_n the_o truth_n of_o which_o wedelius_n be_v force_v to_o confess_v though_o quite_o contrary_a to_o his_o hypothesis_n of_o opium_n fix_v and_o coagulate_v the_o spirit_n give_v a_o instance_n of_o a_o certain_a serene_a person_n who_o when_o she_o have_v any_o affair_n of_o great_a moment_n to_o dispatch_v do_v beforehand_o take_v opium_n with_o great_a advantage_n for_o she_o thereby_o find_v herself_o every_o way_n better_o dispose_v for_o business_n and_o more_o enable_v to_o bear_v the_o fatigue_n thereof_o which_o be_v the_o substance_n of_o what_o he_o write_v in_o latin_n many_o other_o author_n confirm_v the_o truth_n of_o these_o effect_n but_o above_o all_o the_o constant_a experience_n of_o the_o eastern_a nation_n put_v it_o out_o of_o all_o doubt_n 4._o it_o cause_v assurance_n ovation_n of_o the_o spirit_n courage_n contempt_n of_o danger_n and_o magnanimity_n much_o after_o the_o manner_n that_o generous_a wine_n do_v instead_o of_o which_o the_o turk_n etc._n etc._n use_v opium_n before_o engagement_n desperate_a attack_n etc._n etc._n as_o be_v most_o notorious_a to_o make_v they_o courageous_a which_o it_o certain_o do_v for_o your_o satisfaction_n as_o to_o this_o and_o other_o effect_n of_o opium_n not_o so_o common_o observe_v
impossible_a it_o shall_v be_v without_o such_o disturbance_n as_o i_o mention_v will_v follow_v if_o they_o pass_v in_o the_o road_n of_o the_o spirit_n it_o be_v not_o common_a sense_n that_o such_o câ—de_a blast_n shall_v meliorate_v or_o enliven_v the_o spirit_n to_o cause_v briskness_n bravery_n serenity_n courage_n magnanimity_n as_o opium_n do_v much_o less_o if_o those_o fume_n stop_v and_o crowd_v in_o the_o brain_n and_o any_o way_n hinder_v the_o generation_n of_o animal_n spirit_n as_o the_o common_a assertion_n be_v the_o like_a be_v to_o be_v say_v of_o their_o pass_v between_o the_o pia_fw-la mater_fw-la and_o the_o medullary_a part_n of_o the_o nerve_n which_o can_v be_v allow_v because_o of_o its_o close_a adherence_n thereto_o with_o this_o addition_n that_o they_o will_v constant_o cause_v a_o violent_a headache_n which_o opium_n and_o meal_n to_o which_o fume_n be_v particular_o attribute_v do_v often_o cure_v so_o if_o they_o get_v up_o to_o the_o head_n between_o the_o pia_n and_o dura_n mater_n it_o be_v headache_n and_o not_o the_o symptom_n of_o opium_n that_o they_o will_v produce_v which_o headache_n as_o be_v say_v opium_n and_o meal_n do_v cure_v 21._o last_o if_o they_o pass_v by_o any_o mean_n quite_o on_o the_o outside_n of_o the_o nerve_n and_o their_o membrane_n viz._n the_o pia_n and_o dura_n mater_n then_o must_v they_o take_v their_o lodgement_n if_o within_o the_o skull_n between_o the_o dura_n mater_n and_o the_o skull_n and_o produce_v no_o other_o symptom_n but_o a_o headache_n which_o as_o be_v say_v opium_n and_o meal_n rather_o cure_v than_o produce_v and_o if_o without_o the_o skull_n it_o be_v quite_o beside_o the_o cushion_n and_o the_o vaporarian_n own_o intention_n for_o in_o all_o these_o last_o case_n they_o can_v not_o affect_v the_o animal_n spirit_n for_o good_a or_o evil_n many_o and_o very_o many_o thing_n may_v be_v add_v to_o show_v the_o impossibility_n inconvenience_n incoherence_n absurdity_n etc._n etc._n that_o attend_v the_o passage_n of_o the_o fume_n and_o vapour_n into_o the_o brain_n head_n etc._n etc._n 22._o i_o have_v forgotâ—_n mention_v the_o absurdity_n of_o its_o pass_v up_o at_o gullet_n and_o so_o to_o the_o head_n because_o i_o can_v not_o imagine_v that_o any_o one_o will_v be_v so_o beastly_a a_o animal_n as_o to_o belch_v up_o a_o argument_n of_o that_o kind_n consider_v our_o very_a sense_n tell_v we_o that_o what_o come_v up_o that_o way_n pass_v out_o at_o mouth_n or_o nostril_n and_o because_o if_o it_o be_v so_o the_o operation_n of_o opium_n etc._n etc._n will_v be_v in_o proportion_n to_o our_o belch_a which_o be_v ridiculous_a 23._o the_o great_a comfort_n of_o a_o cordial_n be_v at_o first_o or_o soon_o after_o it_o be_v take_v but_o if_o '_o its_o comfort_n be_v by_o fume_n or_o essluvia_n pass_v to_o the_o blood_n or_o any_o where_o beside_o the_o comfort_n will_v as_o their_o cause_n of_o fume_n do_v increase_v for_o a_o long_a time_n and_o be_v more_o after_o a_o good_a while_n than_o at_o first_o so_o 24._o if_o opium_n operate_v by_o fume_n while_o at_o stomach_n which_o must_v gradual_o increase_v continual_o how_o come_v opium_n to_o be_v at_o the_o height_n of_o its_o operation_n in_o a_o short_a time_n viz._n in_o about_o half_a a_o hour_n after_o it_o begin_v sensible_o to_o operate_v or_o a_o hour_n at_o far_a and_o not_o increase_v continual_o in_o its_o operation_n as_o their_o pretend_a cause_n the_o fume_n must_v do_v by_o continual_a steam_a 25._o if_o opium_n operate_v by_o send_v fume_n by_o passage_n etc._n etc._n from_o the_o stomach_n to_o the_o brain_n i_o shall_v think_v that_o when_o it_o have_v get_v out_o of_o the_o stomach_n as_o into_o the_o intestine_n lacteal_v vein_n etc._n etc._n there_o shall_v be_v a_o kind_n of_o interval_n of_o its_o operation_n which_o be_v never_o observe_v till_o it_o get_v into_o the_o blood_n again_o therefore_o it_o do_v not_o operate_v by_o fume_n for_o the_o pylorus_n be_v always_o shut_v but_o when_o somewhat_o be_v send_v downward_o which_o will_v hinder_v the_o mount_a of_o the_o vapour_n into_o the_o stomach_n in_o order_n to_o pass_v to_o the_o brain_n 26._o if_o vapour_n be_v the_o cause_n of_o sleep_n after_o meal_n than_o shall_v we_o be_v more_o sleepy_a two_o or_o three_o hour_n after_o meal_n because_o of_o the_o abundance_n of_o the_o fume_n that_o will_v be_v crowd_v into_o the_o brain_n by_o that_o time_n but_o we_o be_v more_o sleepy_a present_o after_o meal_n and_o if_o we_o indulge_v it_o but_o for_o a_o quarter_n of_o a_o hour_n we_o be_v refresh_v and_o far_o from_o sleepiness_n afterward_o though_o the_o fume_n if_o that_o hypothesis_n be_v true_a will_v be_v much_o more_o at_o brain_n two_o or_o three_o hour_n after_o the_o meal_n so_o it_o be_v in_o the_o case_n of_o wine_n if_o one_o take_v a_o short_a nap_n after_o some_o glass_n he_o may_v drink_v a_o great_a many_o afterward_o without_o be_v sleepy_a which_o plain_o prove_v that_o it_o be_v not_o the_o fume_n of_o the_o wine_n be_v the_o cause_n of_o the_o sleep_n because_o he_o be_v not_o at_o all_o sleepy_a when_o there_o must_v be_v more_o fume_n 27._o all_o allow_v that_o hot_a fume_n assault_v the_o brain_n cause_n frenzy_n if_o that_o be_v true_a than_o the_o fume_n of_o wine_n and_o opium_n which_o be_v both_o very_a hot_a must_v always_o do_v so_o but_o opium_n and_o wine_n also_o do_v often_o cause_v composure_n good_a humour_n sleep_v etc._n etc._n which_o be_v contrary_a to_o frenzy_n therefore_o they_o do_v not_o operate_v by_o fume_n 28._o if_o sleep_n say_v helmont_n the_o only_a man_n that_o i_o have_v read_v who_o be_v against_o vapour_n be_v cause_v by_o vapour_n ascend_v from_o the_o stomach_n to_o the_o head_n obstruct_v and_o intercept_n all_o the_o passage_n of_o sensation_n motion_n speech_n judgement_n etc._n etc._n as_o the_o school_n say_v than_o a_o disease_n will_v have_v be_v before_o the_o fall_n of_o adam_n because_o sleep_n will_v have_v be_v a_o disease_n that_o be_v a_o flatulent_a and_o vaporous_a palsy_n 29._o all_o allow_v vomitives_n and_o purger_n to_o operate_v by_o irritation_n or_o a_o grievous_a sensation_n of_o the_o membrane_n of_o the_o stomach_n why_o not_o wine_n cordial_n opium_n etc._n etc._n by_o a_o pleasant_a sensation_n cujus_fw-la est_fw-la dolour_n aut_fw-la gravamen_fw-la ejusdem_fw-la est_fw-la voluptas_fw-la and_o as_o a_o grievous_a sensation_n or_o pain_n cause_v melancholy_a depression_n of_o spirit_n fretfulness_n lassitude_n etc._n etc._n so_o a_o pleasant_a sensation_n cause_v comfort_n elevation_n of_o the_o spirit_n euphory_n etc._n etc._n but_o we_o have_v not_o clear_v the_o way_n sufficient_o for_o these_o matter_n yet_o which_o will_v in_o due_a time_n be_v solemn_o consider_v obj._n it_o may_v be_v say_v that_o both_o vomitives_n and_o purgative_n take_v some_o time_n before_o they_o operate_v unless_o a_o nausea_n upon_o aversion_n cause_v they_o to_o work_v soon_o for_o thing_n must_v have_v time_n to_o insinuate_v themselves_o or_o soak_v through_o the_o crusta_fw-la carnosa_fw-la of_o the_o stomach_n and_o afterward_o to_o affect_v its_o sensile_a coat_n which_o argue_v that_o wine_n and_o cordial_n which_o operate_v immediate_o do_v not_o operate_v that_o way_n but_o by_o fume_n or_o effuvium_n pass_v into_o the_o brain_n or_o blood_n answ._n i_o doubt_v indeed_o that_o this_o difference_n may_v be_v a_o occasion_n of_o refer_v the_o effect_n of_o cordial_n and_o those_o of_o emittick_n and_o cathartic_o to_o different_a cause_n but_o it_o be_v very_o strange_a that_o they_o shall_v go_v so_o far_o as_o the_o blood_n or_o brain_n to_o seek_v for_o the_o cause_n of_o the_o operation_n of_o cordial_n which_o operate_v in_o a_o moment_n and_o go_v no_o far_o than_o the_o stomach_n for_o the_o cause_n of_o the_o operation_n of_o vomatives_n and_o purgative_n which_o take_v more_o time_n to_o operate_v especial_o see_v the_o blood_n and_o brain_n have_v no_o sensation_n and_o that_o all_o sensitive_a comfort_n happen_v by_o that_o mean_n i_o think_v it_o be_v much_o more_o proper_a first_o to_o consider_v the_o immediate_a part_n upon_o which_o they_o insist_v when_o at_o stomach_n especial_o see_v it_o be_v so_o very_o sensible_a before_o we_o run_v rove_a i_o know_v not_o whither_o to_o seek_v for_o the_o cause_n of_o a_o thing_n that_o work_v please_v and_o comfort_v the_o stomach_n as_o soon_o as_o it_o be_v down_o i_o take_v myself_o run_v off_o the_o proper_a subject_a matter_n of_o this_o chapter_n and_o anticipate_v that_o of_o another_o therefore_o i_o will_v be_v short_a and_o deliver_v my_o opinion_n in_o this_o case_n by_o way_n of_o position_n with_o a_o familiar_a instance_n to_o illustrate_v it_o which_o may_v in_o some_o measure_n prepare_v you_o for_o the_o proof_n
which_o argue_v that_o the_o specific_a combination_n of_o the_o oily_a and_o volatile_a part_n baffle_v all_o coction_n digestion_n circulation_n and_o percolation_n that_o have_v happen_v in_o the_o body_n dioscorides_n and_o aeginela_fw-la speak_v of_o opium_n say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o be_v the_o smell_n of_o the_o medicament_n be_v expanded_a over_o the_o whole_a body_n which_o thing_n of_o its_o nature_n do_v as_o garlic_n onion_n semen_n animale_a which_o cause_v rankness_n all_o over_o male_a creature_n as_o ram_n boar_n bull_n etc._n etc._n 14._o le_fw-fr febure_n in_o his_o chemistry_n part_v 2._o p._n 33_o say_v that_o opium_n have_v a_o volatile_a salt_n inseparable_o mix_v with_o sulphur_n or_o oily_a part_n 15._o wedelius_n in_o his_o opiologia_fw-la lib._n 2._o sect._n 1_o cap._n 4._o p._n 91._o speak_v of_o opium_n say_v sal_fw-la ejus_fw-la cum_fw-la sulphur_n intime_fw-la combinatum_fw-la sudores_fw-la efficit_fw-la that_o be_v its_o salt_n be_v intimate_o combine_v with_o sulphur_n or_o oil_n cause_v sweat_n and_o lib._n 2._o p._n 143._o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d obtinuit_fw-la non_fw-la facile_fw-la dissipabilem_fw-la that_o be_v it_o have_v a_o contexture_n not_o easy_o dissipable_a 18._o all_o know_v how_o apt_a volatile_a salt_n and_o oily_a part_n be_v to_o combine_v therefore_o opium_n act_n and_o produce_v its_o usual_a good_a effect_n by_o a_o sal-volatile-oleosum_a somewhat_o more_o active_a than_o that_o in_o our_o membrane_n who_o principle_n be_v most_o intimate_o and_o strict_o combine_v and_o so_o that_o it_o be_v qualify_v in_o the_o high_a degree_n for_o our_o purpose_n because_o 1._o it_o agree_v in_o principle_n with_o our_o membrane_n 2._o that_o its_o sal-volatile-oleosum_a be_v more_o active_a and_o vigorous_a than_o that_o of_o the_o membrane_n to_o actuate_v and_o excite_v the_o spiritus_fw-la insiti_fw-la and_o fine_o to_o tickle_v and_o gratify_v the_o membrane_n 3._o that_o the_o volatile_a salt_n and_o oily_a part_n be_v so_o intimate_o combine_v do_v delicious_o qualify_v one_o the_o other_o for_o that_o purpose_n while_o the_o oily_a smooth_v and_o lenify_v the_o volatile_a salt_n and_o the_o volatile_a salt_n actuate_v and_o quicken_v the_o oily_a and_o that_o be_v so_o combine_v 4._o both_o conspire_v to_o a_o permanent_a and_o exalt_a pleasure_n of_o the_o membrane_n especial_o at_o stomach_n and_o the_o venereal_a part_n where_o they_o be_v so_o exquisite_o dispose_v for_o sensation_n therefore_o the_o sal-volatile-oleosum_a of_o opium_n separate_v from_o its_o rosin_n be_v most_o consummate_a and_o best_a qualify_v that_o possible_o can_v be_v imagine_v to_o please_v gratify_v and_o fine_o to_o titillate_v our_o membrane_n or_o organ_n of_o sensation_n which_o be_v the_o thing_n require_v i_o can_v better_o illustrate_v its_o nature_n than_o by_o the_o most_o exalt_a thing_n in_o a_o animal_n viz._n it_o be_v semen_n therefore_o for_o confirmation_n of_o its_o principle_n and_o excellency_n therein_o i_o will_v consider_v its_o likeness_n and_o agreement_n therewith_o 1._o in_o be_v both_o a_o shall_v volatile-oleosum_a 2._o in_o have_v a_o more_o active_a vigorous_a and_o exalt_v sal-volatile-oleosum_a than_o any_o part_n of_o the_o animal_n 3._o in_o have_v the_o volatile_a salt_n and_o oleous_a particle_n intimate_o combine_v for_o semen_n animale_a will_v as_o opium_n keep_v very_o long_o uncorrupted_a as_o appear_v by_o its_o long_a stay_n in_o the_o vesiculae_fw-la seminales_fw-la of_o some_o animal_n that_o do_v not_o excern_v it_o in_o many_o year_n 4._o in_o that_o both_o be_v apt_a to_o mix_v with_o all_o fort_n of_o menstruum_n and_o both_o mole_n minimum_n virtute_fw-la maxima_fw-la 5._o in_o have_v much_o the_o same_o smell_n viz._n a_o rank_n and_o vehement_a one_o 6._o in_o taint_v the_o body_n therewith_o as_o have_v be_v show_v 7._o in_o be_v much_o of_o the_o same_o weight_n as_o appear_v by_o both_o sink_n in_o water_n etc._n etc._n 8._o the_o taste_n must_v in_o all_o probability_n have_v a_o rankness_n in_o it_o like_o that_o of_o opium_n because_o it_o give_v a_o rank_a taste_n to_o the_o whole_a body_n of_o male_a creature_n 9_o both_o excite_v venery_n cause_n erection_n venereal_a fury_n and_o nocturnal_a pollution_n etc._n etc._n 10._o both_o cause_n boldness_n courage_n and_o magnanimity_n which_o be_v reckon_v among_o the_o effect_n of_o opium_n and_o be_v the_o common_a effect_n of_o plenitude_n of_o seed_n in_o animal_n that_o be_v otherwise_o pusillanimous_a in_o time_n of_o copulation_n so_o modest_a and_o sheepish_a boy_n grow_v much_o more_o assure_v â—old_a and_o as_o they_o common_o call_v it_o manlike_a upon_o puberty_n and_o girl_n grow_v more_o womanlike_a in_o their_o disposition_n and_o it_o be_v my_o observation_n that_o the_o man_n who_o breed_v most_o of_o the_o sem._n virile_a be_v general_o if_o not_o always_o the_o most_o valiant_a 11._o both_o do_v cause_n a_o great_a relaxation_n upon_o the_o pleasure_n thereof_o as_o appear_v after_o a_o good_a do_v of_o opium_n and_o upon_o emission_n of_o the_o other_o by_o the_o deadness_n of_o the_o eye_n or_o laxity_n of_o the_o cornea_n in_o both_o case_n dilatation_n of_o the_o pupil_n floridity_n of_o the_o skin_n large_a perspiration_n laxity_n of_o the_o limb_n sleepiness_n loss_n of_o memory_n and_o sense_n alienation_n of_o the_o mind_n a_o wide_a pulse_n indolence_n loss_n of_o feel_v in_o both_o case_n and_o other_o sign_n of_o relaxation_n 12._o both_o opium_n and_o puberty_n cause_v a_o growth_n of_o the_o penis_n breast_n and_o increase_v milk_n by_o reason_n of_o the_o relaxation_n that_o they_o cause_n which_o as_o in_o sleep_n cause_v the_o great_a nutrition_n but_o of_o the_o manner_n how_o it_o happen_v upon_o relaxation_n more_o hereafter_o if_o there_o be_v occasion_n hence_o it_o be_v 13._o that_o both_o opium_n and_o puberty_n be_v apt_a to_o bring_v down_o the_o menses_fw-la and_o open_v the_o viae_fw-la by_o the_o relaxation_n and_o that_o marriage_n or_o the_o pleasure_n of_o venereal_a act_n do_v by_o the_o like_a relaxation_n promote_v the_o menses_fw-la that_o both_o opium_n and_o such_o act_n be_v apt_a to_o cause_n miscarriage_n by_o relax_v the_o neck_n of_o the_o womb_n etc._n etc._n 14._o both_o cause_n sadness_n and_o dejection_n when_o the_o operation_n be_v over_o as_o indeed_o pleasure_n general_o do_v especial_o if_o intense_a 15._o both_o opium_n and_o sem._n animale_a prevent_v lassitude_n and_o cause_n euphory_n or_o easy_a undergo_n of_o labour_n hence_o it_o be_v that_o stone_n horse_n will_v not_o be_v so_o soon_o tire_v when_o full_a thereof_o and_o quick_o recover_v if_o tire_a which_o may_v doubtless_o be_v observe_v in_o other_o animal_n but_o that_o they_o be_v not_o use_v to_o labour_n and_o so_o not_o obvious_a to_o be_v observe_v 16._o author_n do_v say_v that_o sem._n virile_a take_v of_o venereal_a impotence_n procure_v love_n etc._n etc._n which_o doubtless_o must_v be_v by_o exciting_a to_o venery_n as_o opium_n do_v thus_o the_o genitals_o of_o buck_n boar_n buck_n of_o hare_n cock_n etc._n etc._n do_v as_o opium_n excite_v venery_n and_o the_o seed_n of_o animal_n as_o of_o a_o camel_n and_o the_o aforesaid_a creature_n come_v to_o be_v esteem_v hypnotick_n and_o doubtless_o all_o animal_n seed_n especial_o of_o the_o more_o salaceous_a creature_n be_v a_o opiate_n in_o some_o degree_n to_o be_v short_a the_o main_a if_o not_o all_o the_o difference_n in_o their_o effect_n arise_v only_o 1._o from_o the_o different_a part_n that_o they_o affect_v because_o opium_n affect_v the_o stomach_n the_o venereal_a and_o all_o the_o membrane_n in_o general_a and_o sem._n animale_a only_a the_o venereal_a part_n immediate_o though_o a_o intense_a pleasure_n of_o one_o part_n do_v affect_v the_o whole_a 2._o that_o opium_n do_v affect_v with_o a_o sense_n of_o pleasure_n more_o permanent_a viz._n for_o many_o hour_n as_o have_v be_v say_v and_o that_o the_o pleasure_n of_o the_o other_o be_v momentary_a therefore_o opium_n act_n by_o cause_v a_o intense_a permanent_a and_o charm_a pleasure_n of_o the_o membrane_n in_o general_a but_o more_o particular_o of_o the_o stomach_n and_o venereal_a part_n as_o be_v more_o exquisite_o dispose_v for_o sensation_n for_o the_o preservation_n of_o the_o individuum_fw-la and_o species_n it_o can_v be_v much_o wonder_v at_o consider_v our_o active_a principle_n be_v a_o sal-volatile-oleosum_a and_o that_o opium_n be_v such_o and_o that_o we_o natural_o carry_v a_o opiate_n within_o we_o that_o in_o some_o case_n our_o ordinary_a sal-volatile-oleosum_a or_o that_o of_o the_o choler_n semen_n etc._n etc._n be_v by_o some_o accident_n exalt_v towards_o the_o nature_n of_o opium_n may_v have_v the_o effect_v of_o a_o opiate_n upon_o we_o by_o cause_v sopor_n and_o lethargic_a distemper_n fuâ—or_fw-la uterinus_fw-la by_o titillation_n etc._n etc._n thus_o the_o spume_n of_o some_o male_a animal_n mummy_n etc._n etc._n
with_o bean_n trefoil_n some_o with_o centaury_n other_o with_o gentian_n etc._n etc._n and_o the_o famous_a dr._n lower_n practice_n run_v almost_o altogether_o upon_o bitter_a thing_n which_o do_v he_o great_a service_n in_o his_o tincture_n of_o steel_n as_o he_o call_v it_o that_o he_o often_o make_v in_o distil_v water_n that_o can_v take_v little_a or_o nothing_o to_o purpose_n of_o the_o tincture_n of_o steel_n whether_o out_o of_o ignorance_n or_o design_n i_o will_v not_o though_o i_o may_v determine_v which_o show_v that_o it_o be_v the_o bitter_a thing_n that_o do_v the_o good_a and_o make_v it_o as_o a_o panacea_fw-la and_o not_o the_o steel_n however_o certain_a it_o be_v that_o promote_a the_o dissolution_n of_o meat_n at_o stomach_n which_o the_o bitter_a salia-volatalia-oleosa_a do_v be_v a_o great_a foundation_n for_o cure_n and_o no_o doubt_n our_o sal-volatile-oleosum_a do_v by_o its_o incide_v divide_v and_o resolve_v quality_n contribute_v very_o much_o to_o a_o due_a solution_n thereof_o at_o stomach_n by_o connaturalness_n as_o all_o menstruum_n do_v especial_o if_o it_o be_v flesh_n which_o we_o use_v most_o and_o require_v most_o help_n to_o be_v resolve_v which_o may_v very_o well_o be_v though_o it_o lessen_v appetite_n by_o please_a sensation_n for_o as_o be_v show_v it_o be_v quite_o another_o thing_n to_o cause_n appetite_n or_o a_o grievous_a sensation_n and_o resolution_n or_o digestion_n of_o the_o meat_n at_o stomach_n for_o wine_n help_v digestion_n yet_o by_o the_o please_a sensation_n that_o it_o cause_n at_o stomach_n it_o cure_v a_o canine_a appetite_n and_o at_o any_o time_n if_o you_o will_v observe_v it_o take_v off_o the_o eagerness_n of_o appetise_n for_o the_o present_a you_o can_v better_o stay_v without_o meat_n after_o a_o whet_v before_o dinner_n than_o you_o can_v without_o it_o so_o that_o the_o wine_n answer_v that_o of_o a_o whet_v as_o to_o digestion_n though_o not_o to_o appetite_n or_o hunger_n which_o be_v a_o grievous_a sensation_n that_o wine_n must_v rather_o cure_v than_o cause_n it_o be_v true_a that_o wine_n or_o opium_n may_v by_o cause_v a_o sense_n of_o pleasure_n at_o stomach_n cause_n some_o stay_n of_o the_o meat_n at_o stomach_n but_o it_o do_v not_o thence_o follow_v but_o the_o digestion_n may_v be_v the_o true_a because_o more_o gentle_a and_o gradual_a as_o it_o may_v and_o do_v happen_v in_o sleep_n when_o thing_n that_o be_v not_o very_o hard_a of_o digestion_n be_v eat_v which_o be_v not_o good_a at_o any_o time_n you_o may_v remember_v how_o blister_n to_o which_o opium_n be_v near_o of_o kind_a as_o have_v be_v show_v do_v quick_o by_o their_o resolve_v nature_n turn_v the_o cuticle_n as_o if_o digest_v into_o a_o sort_n of_o jelly_n what_o a_o mighty_a help_n will_v such_o a_o degree_n of_o resolution_n be_v to_o the_o digestion_n at_o stomach_n when_o it_o be_v by_o that_o mean_n like_o the_o skin_n of_o a_o well_o boil_a cow-heel_n half_o turn_v to_o a_o jelly_n and_o from_o a_o thing_n that_o be_v very_o hard_a of_o digestion_n to_o be_v very_o easy_a as_o be_v also_o a_o boar_n skin_n in_o brawn_n by_o reason_n of_o the_o prior_n resolution_n in_o the_o boil_n if_o as_o sanctorius_n say_v insensible_a perspiration_n hinder_v be_v the_o cause_n of_o most_o disease_n what_o be_v more_o proper_a to_o prevent_v or_o cure_v they_o than_o this_o sal-volatile-oleosum_a which_o cause_v perspiration_n above_o all_o thing_n i_o have_v be_v late_o inform_v that_o in_o some_o part_n of_o the_o most_o eastern_a country_n they_o use_v opium_n as_o a_o general_a medicament_n or_o panacea_fw-la dr._n willis_n and_o silvius_n say_v it_o hinder_v the_o coagulation_n of_o the_o blood_n how_o many_o chronical_a disease_n may_v it_o then_o prevent_v or_o cure_v that_o be_v the_o great_a effect_n of_o the_o alcahest_n and_o that_o be_v it_o that_o main_o qualify_v a_o medicament_n for_o a_o panacea_fw-la as_o courvee_a assert_n and_o all_o ingenious_a man_n allow_v wedelius_n say_v that_o it_o happy_o restore_v the_o tone_n of_o the_o blood_n what_o be_v then_o want_v to_o the_o preservation_n of_o health_n paracelsus_n say_v that_o tam_fw-la homini_fw-la quam_fw-la morbo_fw-la somnum_fw-la conciliat_fw-la that_o be_v that_o it_o put_v the_o disease_n asleep_o as_o well_o as_o the_o man._n ☞_o platerius_n cure_v the_o gout_n with_o it_o safe_o quick_o and_o pleasant_o and_o i_o know_v one_o that_o can_v do_v it_o especial_o if_o it_o be_v at_o the_o first_o come_v of_o the_o fit_n willis_n give_v a_o instance_n of_o one_o perfect_o cure_v of_o a_o dropsy_n and_o pocky_a pain_n by_o the_o use_n of_o laudanum_n ☞_o horstius_fw-la perfect_o cure_v a_o hypochondriacal_a person_n that_o be_v trouble_v with_o stupidity_n watch_n loss_n of_o appetite_n tremble_v and_o direful_a epileptical_a convulsion_n and_o past_o all_o hope_n by_o the_o use_n of_o opiate_n i_o myself_o have_v often_o see_v defluxion_n and_o catarrh_n cure_v by_o the_o use_n of_o opiate_n and_o one_o of_o a_o inveterate_a ill_a habit_n of_o body_n of_o many_o year_n stand_v wedelius_n say_v that_o it_o resolve_v the_o grumescence_n of_o the_o blood_n alter_v and_o dissipate_v the_o tenuious_a part_n of_o it_o temper_n the_o acrimonious_a etc._n etc._n the_o ancient_n use_v it_o against_o ague_n with_o great_a success_n you_o may_v to_o confirm_v this_o matter_n far_a observe_v that_o among_o the_o constant_a and_o frequent_a effect_n of_o opium_n there_o be_v no_o bad_a one_o unless_o there_o be_v 2_o or_o 3_o pure_o upon_o the_o account_n of_o its_o rosin_n as_o have_v be_v show_v therefore_o when_o it_o be_v separate_v from_o it_o there_o be_v no_o cause_n to_o fear_v the_o use_n of_o the_o sal-volatile-oleosum_a unless_o it_o be_v as_o in_o the_o case_n of_o wine_n when_o it_o be_v take_v in_o a_o excessive_a do_v or_o use_v too_o long_o in_o a_o lavish_a intemperate_a manner_n so_o that_o when_o i_o have_v show_v how_o due_o to_o prepare_v it_o and_o the_o moderate_a and_o safe_a dose_n thereof_o it_o may_v be_v use_v altogether_o as_o safe_o as_o wine_n in_o a_o proportionable_a do_v for_o what_o harm_n can_v there_o be_v in_o moderate_o please_v the_o membrane_n particular_o at_o stomach_n which_o all_o the_o best_a thing_n we_o use_v as_o wine_n cordial_n meat_n and_o drink_v do_v which_o be_v therefore_o all_o opiate_n in_o some_o degree_n thereby_o assure_v we_o of_o their_o goodness_n and_o agreeableness_n to_o our_o body_n though_o they_o do_v it_o not_o in_o so_o high_a a_o dgree_n as_o our_o sal-volatile-oleosum_a do_v which_o be_v the_o more_o authentic_a certificate_n of_o its_o excellency_n though_o it_o be_v to_o be_v still_o confess_v that_o excess_n of_o the_o best_a thing_n as_o joy_n comfort_n pleasure_n wine_n cordial_n etc._n etc._n have_v and_o may_v do_v mischief_n but_o what_o need_v excess_n therein_o any_o more_o than_o in_o wine_n meat_n cordial_n etc._n etc._n which_o then_o like_v it_o be_v all_o inconvenient_a and_o injurious_a to_o the_o body_n all_o this_o i_o have_v say_v to_o administer_v cause_n to_o improve_v the_o practice_n of_o physic_n by_o the_o use_n of_o this_o panacea_fw-la now_o that_o it_o be_v know_v by_o introduce_v its_o noble_a use_n as_o a_o alterative_a to_o cure_n as_o well_o as_o former_o to_o palliate_v disease_n it_o be_v a_o far_o more_o beneficial_a thing_n to_o cure_v than_o palliate_v remember_v how_o the_o cortex_fw-la mercury_n antimony_n and_o other_o the_o most_o effectual_a and_o glorious_a medicament_n have_v be_v traduce_v and_o scandalize_v by_o the_o ignorant_a imagination_n of_o the_o unlearned_a who_o have_v no_o true_a knowledge_n of_o the_o virtue_n of_o thing_n whole_o depend_v upon_o fear_n and_o jealousy_n to_o guard_v they_o from_o their_o imagine_a ill_a effect_n which_o general_o speak_v only_o the_o same_o ignorance_n fear_n and_o jealousy_n give_v a_o fantastical_a be_v to_o it_o remain_v that_o i_o in_o the_o next_o place_n show_v you_o 1._o the_o true_a preparation_n of_o this_o panacea_fw-la or_o sal-volatile-oleosum_a 2._o other_o preparation_n of_o opium_n that_o be_v next_o it_o in_o safety_n and_o good_a effect_n and_o why_o they_o be_v so_o 3._o the_o moderate_a and_o true_o safe_a dose_v of_o they_o all_o there_o be_v no_o danger_n in_o well_o prepare_v opium_n but_o from_o excess_n in_o the_o use_v thereof_o chap._n xxv_o of_o the_o preparation_n of_o the_o panacea_fw-la or_o true_a sal-volatile-oleosum_a of_o opium_n see_v that_o the_o sal-volatile-oleosum_a of_o opium_n must_v be_v such_o a_o effectual_a generous_a and_o general_a medicament_n that_o be_v both_o cordial_a and_o alterative_a in_o so_o transcendent_a a_o manner_n it_o well_o deserve_v a_o careful_a and_o curious_a preparation_n therefore_o i_o will_v be_v very_o particular_a therein_o to_o that_o end_n 1._o it_o must_v be_v separate_v from_o all_o the_o
a_o very_o long_o and_o lavish_a use_n thereof_o the_o inconvenience_n of_o leave_v off_o the_o use_n of_o opium_n do_v bear_v a_o certain_a proportion_n to_o the_o time_n and_o quantity_n that_o it_o have_v be_v use_v in_o 1._o note_v that_o the_o turk_n do_v drink_v some_o water_n always_o after_o the_o take_n of_o opium_n as_o be_v the_o best_a menstruum_fw-la to_o dissolve_v it_o 2._o note_v that_o it_o be_v usual_a with_o they_o to_o take_v a_o drachm_n in_o the_o morning_n and_o so_o much_o in_o the_o afternoon_n and_o so_o may_v we_o as_o well_o as_o they_o if_o use_v to_o it_o and_o it_o be_v a_o very_a silly_a say_n that_o you_o will_v find_v in_o author_n that_o they_o be_v better_a able_a to_o bear_v it_o because_o of_o the_o climate_n etc._n etc._n whereas_o the_o more_o northern_a person_n be_v better_a able_a to_o take_v it_o than_o the_o southern_a as_o will_v hereafter_o appear_v most_o plain_o i_o be_o tell_v of_o one_o near_o banbury_n that_o take_v two_o ounce_n a_o day_n 3._o note_v that_o among_o the_o effect_n of_o opium_n may_v be_v observe_v many_o seem_a contradiction_n yet_o be_v there_o nothing_o more_o certain_a than_o the_o several_a different_a matter_n of_o fact_n which_o no_o doubt_n have_v be_v a_o great_a cause_n to_o puzzle_v the_o world_n about_o it_o and_o to_o run_v man_n into_o strange_a absurdity_n concern_v its_o operation_n and_o all_o to_o deviate_v so_o far_o from_o the_o truth_n that_o nothing_o in_o nature_n can_v be_v far_o unless_o you_o will_v say_v that_o heat_n cool_v or_o what_o please_v the_o sensitive_a soul_n be_v at_o the_o same_o time_n abhor_v by_o it_o now_o because_o these_o seem_a contradiction_n in_o the_o effect_n of_o opium_n be_v the_o great_a rub_n to_o be_v meet_v with_o and_o that_o the_o reader_n may_v take_v the_o better_a estimate_n of_o the_o undertake_n and_o my_o explication_n of_o its_o effect_n when_o i_o come_v to_o it_o i_o shall_v not_o fear_v to_o enumerate_v they_o distinct_o though_o they_o will_v make_v the_o strange_a catalogue_n of_o riddle_n that_o ever_o be_v see_v trust_v in_o he_o that_o create_v this_o wonderful_a medicament_n that_o he_o will_v enable_v i_o to_o explain_v all_o its_o effect_n the_o seem_a contradiction_n in_o the_o effect_n of_o opium_n 1._o it_o cause_v sleep_v and_o watch_v 2._o it_o cause_n and_o prevent_v sweat_n 3._o it_o relax_n and_o stop_v looseness_n 4._o it_o stop_v flux_n and_o cause_n that_o of_o sweat_n etc._n etc._n 5._o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v by_o that_o sense_n to_o venery_n 6._o it_o cause_v stupidity_n and_o promptitude_n in_o business_n cloudiness_n and_o serenity_n of_o mind_n 7._o it_o excite_v the_o spirit_n and_o quiet_v they_o 8._o it_o be_v very_o hot_a yet_o cool_v in_o fever_n 9_o it_o be_v hot_a and_o bitter_a yet_o lessen_v appetite_n even_o in_o cold_a stomach_n 10._o it_o stop_v and_o promote_v urine_n 11._o it_o relax_n and_o weaken_v yet_o enable_v we_o to_o undergo_v labour_n journey_n etc._n etc._n 12._o it_o cause_n and_o prevent_v abortion_n 13._o it_o stop_v vomit_v above_o all_o thing_n yet_o cause_n most_o violent_a tedious_a and_o dangerous_a vomit_n 14._o it_o stop_v purge_v in_o a_o most_o eminent_a manner_n yet_o sometime_o cause_v it_o 15._o it_o be_v very_o acrimonious_a yet_o as_o all_o say_v obtund_v acrimony_n however_o it_o allay_v pain_n proceed_v from_o acrimony_n 16._o it_o cause_v a_o furious_a madness_n yet_o compose_v the_o spirit_n above_o all_o thing_n 17._o it_o cause_v 〈◊〉_d yet_o sometime_o cure_v they_o as_o willis_n say_v 18._o it_o cause_v palsy_n yet_o have_v i_o know_v it_o to_o cure_v a_o palsy_n 19_o it_o cause_v dryness_n in_o the_o mouth_n yet_o take_v off_o thirst_n in_o fever_n 20._o it_o cure_v and_o cause_v a_o hiccough_n 21._o it_o stanche_n blood_n yet_o cause_v the_o blood_n to_o come_v outward_a as_o appear_v by_o the_o efflorescence_n or_o redness_n of_o the_o skin_n that_o it_o cause_n yet_o move_v the_o menses_fw-la and_o lochia_n 22._o we_o have_v many_o instance_n of_o it_o promote_a and_o hinder_v critical_a motion_n 23._o it_o raise_v very_o weak_a people_n when_o nothing_o beside_o will_v do_v it_o yet_o it_o kill_v other_o weak_a people_n 24._o it_o cause_n and_o cure_n convulsion_n 25._o it_o cause_v relaxation_n and_o contraction_n of_o the_o same_o part_n 26._o it_o relax_n yet_o cause_v rigidity_n tension_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n thus_o have_v i_o fair_o and_o faithful_o lay_v the_o whole_a onus_fw-la of_o the_o operation_n effect_n and_o contradictory_n phenomena_n of_o opium_n upon_o my_o shoulder_n however_o i_o come_v off_o and_o clear_v myself_o of_o the_o intricacy_n maze_n and_o cross_a effect_n thereof_o by_o explain_v they_o which_o none_o upon_o the_o view_n thereof_o will_v think_v possible_a and_o none_o before_o i_o dare_v as_o much_o as_o enumerate_v for_o that_o end_n chap._n vii_o the_o author_n contrive_v a_o compendious_a way_n of_o examine_v all_o opinion_n concern_v the_o operation_n of_o opium_n have_v without_o any_o sly_a or_o sordid_a evasion_n or_o considerable_a omission_n which_o have_v be_v the_o perfidious_a course_n of_o author_n in_o this_o case_n full_o and_o true_o enumerate_v the_o sensible_a and_o certain_a effect_n of_o opium_n in_o humane_a body_n and_o thereby_o empanneled_a a_o just_a jury_n for_o the_o trial_n of_o hypothesise_n which_o must_v be_v judge_v by_o the_o effect_n or_o phenomena_n of_o opium_n i_o will_v now_o proceed_v to_o their_o examination_n but_o because_o it_o will_v be_v endless_a to_o take_v every_o one_o particular_o into_o consideration_n i_o will_v use_v their_o stratagem_n who_o blow_v up_o foundation_n to_o save_v the_o tedious_a peck_v at_o all_o the_o part_n of_o the_o superstructure_n which_o in_o this_o case_n will_v require_v a_o age_n and_o take_v up_o all_o my_o time_n in_o demolish_n they_o which_o may_v be_v better_o employ_v in_o erect_v something_o that_o may_v be_v useful_a i_o have_v consider_v and_o find_v that_o the_o foundation_n in_o which_o all_o author_n both_o ancient_a and_o modern_a agree_v and_o whereupon_o they_o have_v hitherto_o endeavour_v to_o build_v look_v upon_o it_o as_o firm_a and_o warrantable_a in_o all_o age_n be_v this_o viz._n that_o opium_n operate_v by_o diminish_v or_o disable_n the_o spirit_n mean_v the_o animal_n spirit_n the_o ancient_n affirm_v that_o it_o do_v so_o by_o a_o extreme_a cold_a quality_n etc._n etc._n and_o the_o modern_n who_o observe_v it_o to_o act_n while_o it_o be_v at_o stomach_n by_o affect_v the_o brain_n nerve_n animal_n spirit_n etc._n etc._n and_o conclude_v no_o action_n be_v perform_v without_o contact_n infer_v and_o agree_v because_o no_o visible_a passage_n can_v be_v find_v from_o the_o stomach_n to_o the_o head_n that_o it_o must_v of_o absolute_a necessity_n act_v by_o fume_n vapour_n auras_fw-la or_o effluvium_n send_v up_o out_o of_o the_o stomach_n to_o the_o brain_n nerve_n etc._n etc._n so_o that_o all_o the_o remain_a question_n among_o the_o modern_n be_v which_o way_n those_o fume_n or_o vapour_n do_v the_o feat_n all_o allow_v the_o fume_n do_v it_o one_o say_v that_o they_o stuff_v the_o pore_n of_o the_o brain_n and_o so_o hinder_v the_o generation_n of_o animal_n spirit_n a_o second_o that_o they_o constringed_a and_o close_v the_o pore_n together_o thereby_o hinder_v the_o say_a generation_n a_o three_o that_o they_o fix_v and_o coagulate_v the_o animal_n spirit_n as_o wedelius_n and_o other_o a_o four_o that_o they_o cloud_v the_o animal_n spirit_n a_o five_o that_o they_o act_v as_o a_o poison_n as_o willis_n and_o many_o other_o a_o six_o that_o they_o clog_v the_o animal_n spirit_n by_o adhere_v to_o they_o etc._n etc._n not_o know_v nor_o i_o think_v care_v what_o they_o say_v so_o they_o humour_a their_o own_o imagination_n and_o hypothesise_n though_o utter_o incapable_a of_o solve_v the_o effect_n of_o opium_n especial_o be_v most_o constant_a proper_a and_o genuine_a effect_n for_o how_o can_v a_o cold_a quality_n which_o opium_n never_o have_v cause_v a_o gay_a and_o brisk_a humour_n bravery_n magnanimity_n euphory_n in_o labour_n promptitude_n to_o venus_n etc._n etc._n and_o how_o can_v cloud_n of_o vapour_n hinder_v the_o generation_n of_o animal_n spirit_n by_o stuff_v or_o constr_v the_o pore_n of_o the_o brain_n poison_v fix_v coagulate_v clog_a or_o cloud_v the_o animal_n spirit_n cause_v a_o fine_a ovation_n thereof_o a_o gay_a brave_a courageous_a and_o magnanimous_a disposition_n euphory_n promptitude_n to_o venery_n serenity_n expediteness_n in_o management_n etc._n etc._n which_o be_v as_o have_v be_v say_v the_o constant_a and_o proper_a effect_n of_o opium_n nor_o indeed_o be_v any_o of_o those_o author_n so_o foolhardy_a as_o to_o attempt_v it_o
why_o then_o do_v they_o write_v and_o trouble_v the_o world_n to_o peruse_v their_o book_n when_o they_o be_v so_o far_o from_o explain_v the_o property_n of_o opium_n that_o they_o scarce_o ever_o dare_v mention_v they_o nor_o set_v their_o hypothesise_n and_o they_o as_o much_o as_o in_o view_n of_o one_o another_o be_v not_o this_o a_o tacit_n confession_n of_o the_o incompetency_n of_o their_o supposition_n i_o beg_v pardon_n for_o call_v they_o they_o though_o they_o themselves_o do_v for_o i_o can_v offer_v they_o a_o great_a abuse_n than_o lay_v their_o spurious_a and_o lame_a brat_n at_o their_o door_n though_o one_o scarce_o need_v say_v any_o more_o of_o they_o yet_o lest_o i_o be_v think_v presumptuous_a or_o saucy_a for_o so_o much_o as_o offer_v to_o suspect_v the_o general_a foundation_n of_o all_o the_o famous_a author_n that_o ever_o live_v as_o galen_n avicenna_n etc._n etc._n among_o the_o ancient_n etmuller_n willis_n etc._n etc._n among_o the_o modern_n 1._o i_o will_v show_v you_o very_o just_a cause_n to_o suspect_v the_o insufficiency_n of_o the_o general_a foundation_n viz._n that_o opium_n diminish_v or_o disable_v the_o spirit_n 2._o i_o will_v prove_v that_o it_o do_v not_o do_v it_o by_o a_o cold_a quality_n 3._o that_o it_o do_v not_o do_v it_o by_o vapour_n fume_n aura_n or_o any_o such_o way_n 4._o that_o it_o diminish_v or_o disable_v the_o spirit_n by_o no_o mean_n whatsoever_o which_o diminish_v or_o disable_n of_o the_o spirit_n cold_a quality_n and_o fume_n or_o aura_n comprehend_v the_o foundation_n of_o all_o opinion_n concern_v opium_n that_o ever_o i_o read_v or_o hear_v of_o and_o consequent_o if_o those_o two_o fundamental_a opinion_n be_v refute_v all_o the_o superstructure_n that_o have_v be_v in_o this_o case_n must_v fall_v to_o the_o ground_n chap._n viii_o the_o author_n show_v just_a cause_n of_o his_o suspicion_n that_o all_o author_n have_v go_v upon_o a_o wrong_a foundation_n in_o their_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n i_o have_v show_v you_o that_o the_o general_a foundation_n of_o both_o ancient_n and_o modern_a author_n be_v that_o opium_n do_v diminish_v or_o disable_v the_o spirit_n and_o now_o i_o will_v plain_o show_v just_a cause_n of_o my_o suspicion_n of_o its_o insufficiency_n which_o be_v these_o 1._o i_o observe_v that_o all_o learned_a man_n be_v to_o this_o day_n high_o dissatisfy_v as_o to_o the_o cause_n and_o manner_n of_o the_o operation_n of_o opium_n notwithstanding_o all_o that_o have_v be_v write_v concern_v it_o and_o that_o it_o be_v the_o common_a cry_n on_o all_o hand_n that_o none_o have_v illustrate_v the_o operation_n of_o opium_n to_o any_o purpose_n or_o give_v any_o satisfaction_n therein_o and_o therefore_o learned_a physician_n be_v still_o as_o much_o upon_o the_o enquiry_n as_o ever_o they_o be_v it_o be_v much_o more_o civil_a and_o reasonable_a to_o suspect_v the_o foundation_n that_o all_o former_a author_n have_v build_v upon_o than_o a_o general_a failure_n in_o all_o the_o most_o judicious_a master_n builder_n that_o ever_o endeavour_v to_o build_v thereon_o for_o if_o all_o the_o best_a architect_n of_o the_o whole_a world_n fail_v to_o erect_v a_o firm_a superstructure_n upon_o any_o one_o foundation_n what_o can_v we_o think_v but_o that_o the_o foundation_n be_v infirm_a especial_o when_o as_o in_o our_o case_n no_o way_n that_o care_n judgement_n perspicacity_n and_o wit_n can_v invent_v or_o think_v of_o have_v be_v leave_v untried_a to_o build_v thereon_o so_o that_o though_o i_o modest_o call_v it_o a_o cause_n of_o suspicion_n it_o amount_v almost_o if_o not_o altogether_o to_o a_o demonstration_n that_o the_o foundation_n that_o all_o author_n have_v go_v upon_o be_v naught_o will_v not_o any_o consider_a man_n when_o he_o see_v all_o the_o judicious_a architect_n of_o the_o world_n fail_v to_o erect_v a_o firm_a building_n upon_o a_o certain_a foandation_n seek_v for_o another_o therefore_o who_o can_v blame_v i_o if_o i_o do_v and_o not_o blame_v they_o that_o do_v not_o the_o mean_a bricklayer_n or_o carpenter_n that_o shall_v be_v guilty_a of_o such_o stupidity_n as_o to_o attempt_v to_o build_v upon_o such_o a_o foundation_n as_o always_o deceive_v the_o builder_n will_v be_v think_v too_o great_a a_o blockhead_n to_o be_v employ_v in_o building_n 2._o i_o observe_v that_o most_o man_n do_v notwithstanding_o that_o foundation_n be_v agree_v upon_o think_v it_o impossible_a to_o explain_v the_o intricate_a various_a contradictory_n phenomena_n and_o mysterious_a effect_n of_o opium_n sit_v content_v and_o persuade_v that_o it_o operate_v by_o a_o occult_a quality_n whole_o unexplicable_a and_o particular_o reserve_v from_o the_o knowledge_n of_o mankind_n but_o nature_n work_v mechanical_o in_o weight_n measure_n etc._n etc._n therefore_o it_o be_v more_o than_o probable_a that_o it_o be_v only_o their_o be_v upon_o a_o wrong_a bottom_n make_v it_o seem_v absolute_o occult_a for_o it_o be_v impossible_a to_o find_v a_o thing_n where_o it_o be_v not_o or_o to_o build_v firm_o upon_o a_o insufficient_a foundation_n whereas_o have_v it_o be_v right_o and_o true_a it_o be_v not_o to_o be_v imagine_v but_o some_o or_o other_o will_v have_v thereupon_o do_v something_o that_o will_v have_v stand_v against_o all_o wind_n and_o storm_n which_o none_o have_v do_v 3._o i_o observe_v that_o none_o dare_v venture_v to_o lay_v the_o whole_a no_o nor_o one_o half_a of_o the_o burden_n of_o the_o phinomena_n or_o effect_n of_o opium_n upon_o that_o foundation_n foresee_v doubtless_o that_o it_o can_v not_o bear_v they_o and_o that_o if_o they_o lay_v any_o more_o weight_n thereon_o the_o whole_a will_v totter_v and_o fall_v to_o the_o ground_n the_o project_n in_o every_o hypothesis_n be_v to_o persuade_v man_n of_o the_o truth_n thereof_o and_o the_o only_a way_n to_o do_v it_o be_v to_o solve_v all_o phenomena_n thereby_o for_o if_o it_o fail_v but_o in_o one_o it_o be_v a_o infallible_a sign_n of_o its_o insufficiency_n there_o be_v no_o reason_n to_o omit_v any_o of_o the_o phenomena_n if_o they_o can_v have_v discern_v that_o the_o hypothesis_n will_v have_v bear_v they_o therefore_o as_o have_v be_v intimate_v it_o imply_v a_o confession_n of_o its_o incompetency_n 4._o i_o observe_v that_o ancient_a author_n write_v of_o opium_n before_o it_o come_v to_o be_v of_o common_a and_o general_a use_n in_o the_o daytime_n with_o healthy_a person_n as_o it_o since_o be_v in_o many_o nation_n to_o cause_v a_o gay_a pleasant_a and_o good_a humour_n take_v off_o sadness_n melancholy_a and_o anxiety_n to_o cause_n assurance_n boldness_n courage_n bravery_n magnanimity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n promptitude_n in_o business_n expediteness_n and_o serenity_n to_o excite_v to_o venery_n etc._n etc._n which_o effect_n can_v be_v explain_v by_o that_o supposition_n of_o disable_n the_o spirit_n and_o that_o they_o use_v opium_n only_a medicinally_n for_o the_o sake_n of_o such_o other_o effect_n as_o may_v be_v tolerable_o well_o explicate_v by_o that_o hypothesis_n so_o that_o they_o have_v not_o any_o occasion_n nor_o inducement_n to_o look_v any_o far_o the_o effect_n they_o give_v it_o for_o be_v only_o 1._o to_o cause_v sleep_n 2._o to_o take_v off_o pain_n 3._o to_o stop_v flux_n 4._o to_o compose_v the_o spirit_n 5._o to_o cause_v perspiration_n and_o sweat_n all_o which_o be_v not_o inconsistent_a with_o the_o hypothesis_n of_o diminish_v or_o disable_n the_o spirit_n as_o the_o other_o be_v and_o therefore_o may_v well_o deceive_v they_o for_o first_o sleep_n be_v cause_v by_o diminish_v the_o spirit_n by_o labour_n watch_v etc._n etc._n as_o be_v most_o notorious_a over_o the_o whole_a world_n so_o other_o thing_n that_o diminish_v the_o spirit_n as_o bleed_v vomit_v purge_v and_o many_o other_o cause_n of_o diminish_v thereof_o do_v incline_v we_o to_o sleep_v second_o indolence_n or_o exemption_n from_o pain_n be_v cause_v by_o nothing_o more_o than_o want_v of_o spirit_n as_o in_o paralytical_a case_n stuporâ—_n obstruction_n or_o compression_n of_o the_o nerve_n syncopes_fw-la leipothymy_n deliquium_n faint_n after_o bleed_v and_o sleep_v which_o as_o be_v say_v be_v so_o much_o cause_v by_o loss_n of_o spirit_n etc._n etc._n three_o flux_n be_v stop_v or_o moderate_v by_o nothing_o better_a than_o sleep_n which_o general_o as_o be_v say_v proceed_v from_o loss_n of_o spirit_n what_o also_o stop_v or_o moderate_v flux_n more_o than_o want_v of_o the_o sense_n of_o the_o irritation_n of_o humour_n and_o what_o take_v away_o sense_n more_o than_o want_v of_o spirit_n thus_o want_v of_o sense_n by_o the_o absence_n of_o the_o spirit_n in_o paralytical_a intestine_n stop_v flux_n thus_o fail_v a_o paralytical_a bladder_n to_o express_v the_o urine_n so_o a_o palsy_n of_o the_o membrane_n
or_o vapour_n do_v ready_o and_o free_o pass_v from_o the_o stomach_n to_o the_o brain_n because_o the_o gross_a fume_n as_o they_o call_v they_o of_o a_o grain_n or_o two_o of_o opium_n always_o operate_v before_o it_o be_v out_o of_o the_o stomach_n but_o they_o never_o see_v such_o fume_n pass_v nor_o their_o passage_n only_o suppose_v both_o and_o that_o mere_o upon_o a_o imagination_n that_o it_o must_v be_v so_o because_o they_o forsooth_o can_v conceive_v any_o other_o way_n by_o which_o opium_n can_v affect_v the_o head_n nerve_n etc._n etc._n while_o it_o be_v at_o stomach_n whereas_o i_o can_v and_o shall_v god_n will_v show_v they_o another_o mean_n or_o way_n to_o do_v it_o that_o be_v sensible_a and_o not_o whole_o precarious_a as_o they_o be_v and_o that_o in_o the_o mean_a manner_n because_o all_o their_o ground_n to_o suppose_v it_o be_v their_o inability_n to_o conceive_v or_o apprehend_v what_o be_v as_o i_o shall_v show_v very_o sensible_a nay_o obvious_a also_o second_o they_o suppose_v that_o such_o fume_n will_v serve_v to_o solve_v all_o the_o phoenomena_n and_o operation_n of_o opium_n whereas_o it_o be_v utter_o impossible_a they_o shall_v solve_v the_o enliven_a and_o invigorate_n effect_n thereof_o as_o have_v be_v show_v and_o shall_v be_v further_o prove_v if_o god_n permit_v it_o be_v easy_a to_o evidence_n but_o that_o it_o will_v be_v tedious_a and_o needless_a for_o their_o incompetency_n to_o solve_v the_o most_o proper_a effect_n of_o opium_n be_v more_o than_o enough_o that_o such_o fume_n or_o vapour_n can_v true_o solve_v no_o effect_n of_o opium_n unless_o it_o be_v that_o of_o death_n or_o some_o deadly_a symptom_n nay_o they_o will_v not_o solve_v the_o most_o likely_a to_o be_v cause_v by_o vapour_n viz._n sleep_v which_o all_o man_n as_o wedelius_n say_v allow_v to_o be_v the_o effect_n of_o fume_n or_o vapour_n in_o his_o opiologia_fw-la c._n 11._o p._n 35._o somnum_fw-la naturalem_fw-la say_v he_o omnes_fw-la concedunt_fw-la producere_fw-la suaviores_fw-la &_o blandas_fw-la 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d seu_fw-la vapores_fw-la primum_fw-la 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d demulcentes_fw-la qui_fw-la cum_fw-la spiritibus_fw-la animalibus_fw-la mixti_fw-la torpidos_fw-la quasi_fw-la illos_fw-la reddunt_fw-la that_o be_v all_o grant_v that_o kind_n and_o gentle_a fume_n do_v cause_n natural_a sleep_n etc._n etc._n which_o be_v most_o certain_o false_a though_o i_o very_o much_o doubt_n that_o this_o groundless_a presumption_n which_o as_o he_o intimate_v all_o embrace_n have_v be_v a_o great_a cause_n of_o this_o airy_a imagination_n of_o fume_n in_o the_o case_n of_o opium_n because_o man_n look_v upon_o sleep_n agree_v upon_o to_o be_v cause_v by_o fume_n to_o be_v the_o prime_n lead_v and_o most_o proper_a effect_n of_o opium_n which_o be_v also_o false_a it_o be_v but_o a_o mere_a accident_n as_o have_v be_v show_v and_o when_o it_o happen_v general_o require_v lie_v or_o sit_v still_o to_o assist_v it_o whereas_o the_o watch_a that_o be_v the_o effect_n of_o opium_n require_v no_o help_n and_o can_v be_v put_v off_o as_o sleep_n can_v by_o motion_n action_n etc._n etc._n notwithstanding_o all_o endeavour_n to_o the_o contrary_n now_o i_o will_v know_v of_o any_o man_n which_o be_v the_o most_o proper_a and_o natural_a effect_n of_o any_o cause_n that_o which_o nothing_o can_v hinder_v or_o that_o which_o every_o action_n can_v but_o i_o run_v too_o far_o upon_o this_o matter_n which_o belong_v more_o apt_o to_o that_o part_n of_o this_o book_n that_o explain_v all_o the_o effect_n of_o opium_n and_o so_o must_v return_v to_o that_o of_o fume_n which_o do_v not_o cause_v natural_a sleep_n as_o manifest_o appear_v 1._o because_o that_o which_o cause_v natural_a sleep_n must_v in_o all_o reason_n as_o it_o be_v always_o in_o the_o wise_a work_n of_o nature_n bear_v a_o proportion_n thereto_o but_o fume_n suppose_v their_o be_v bear_v no_o proportion_n to_o our_o sleep_n certain_o a_o work_a labourer_n that_o toil_v all_o the_o day_n must_v spend_v the_o fume_n of_o his_o body_n in_o the_o high_a degree_n and_o feed_v upon_o dry_a bread_n and_o cheese_n must_v breed_v few_o fume_n yet_o none_o sleep_v better_a or_o sweet_a than_o he_o the_o like_a be_v to_o be_v say_v of_o a_o travel_a man_n a_o tire_a person_n etc._n etc._n who_o often_o fall_v asleep_a before_o they_o eat_v or_o drink_v to_o renew_v their_o fume_n which_o they_o have_v spend_v in_o a_o extraordinary_a manner_n why_o sleep_n that_o be_v design_v for_o refreshment_n and_o recruit_v shall_v depend_v upon_o fume_n no_o man_n can_v tell_v for_o than_o our_o refreshment_n will_v whole_o depend_v thereon_o and_o no_o man_n have_v any_o recruit_v by_o sleep_n but_o in_o proportion_n thereunto_o who_o dare_v accuse_v our_o wise_a and_o good_a maker_n of_o such_o contrivance_n who_o in_o nature_n always_o proportion_n thing_n to_o the_o exigency_n thereof_o and_o therefore_o sleep_v not_o to_o fume_n but_o to_o that_o which_o be_v impair_v in_o we_o for_o want_v thereof_o which_o be_v always_o contrive_v by_o wise_a nature_n if_o you_o will_v observe_v it_o to_o be_v the_o prompt_a cause_n to_o the_o recruit_v and_o then_o proportion_n be_v due_o observe_v because_o we_o be_v prompt_v exact_o according_a to_o the_o exigence_n or_o necessity_n of_o nature_n as_o become_v the_o wisdom_n of_o our_o creator_n and_o preserver_n this_o rule_n if_o due_o attend_v to_o will_v easy_o speedy_o and_o certain_o lead_v you_o to_o the_o knowledge_n of_o the_o true_a natural_a cause_n of_o hunger_n thirst_v inclination_n to_o sleep_n and_o all_o such_o call_v for_o restauration_n all_o which_o i_o can_v soon_o satisfy_v you_o in_o but_o that_o it_o be_v not_o my_o business_n at_o present_a and_o that_o it_o will_v too_o much_o anticipate_v my_o design_a tract_n of_o animal_n mechanism_n nor_o do_v labour_v itself_o bear_v any_o exact_a proportion_n thereunto_o because_o many_o healthy_a people_n that_o be_v idle_a all_o day_n sleep_v long_o sound_o and_o sweet_o every_o night_n as_o well_o as_o labourer_n so_o that_o in_o short_a it_o must_v be_v somewhat_o that_o belong_v to_o watch_v as_o such_o for_o sleep_v general_o bear_v the_o best_a proportion_n to_o watch_v if_o we_o watch_v much_o or_o little_a our_o sleep_n bear_v some_o proportion_n thereto_o though_o there_o may_v be_v in_o this_o as_o well_o as_o in_o hunger_n thirst_v etc._n etc._n accident_n that_o cause_n the_o promptitude_n to_o be_v more_o or_o less_o and_o so_o vary_v the_o true_a natural_a proportion_n all_o which_o have_v the_o nature_n of_o disease_n as_o canine_a appetite_n coma_n caros_n preternatural_a thrists_z etc._n etc._n what_o it_o be_v that_o watch_a cause_n to_o prompt_v we_o to_o sleep_n must_v be_v some_o impair_v make_v thereby_o as_o such_o and_o not_o the_o foolish_a conceit_n of_o fume_n and_o it_o be_v easy_a for_o i_o to_o illustrate_v what_o it_o be_v but_o that_o it_o will_v require_v some_o sheet_n of_o paper_n and_o as_o i_o say_v before_o anticipate_v my_o discourse_n of_o animal_n mechanism_n which_o i_o hope_v to_o have_v publish_v before_o this_o book_n and_o will_v have_v be_v most_o convenient_a because_o the_o principle_n therein_o state_v may_v serve_v to_o explain_v the_o effect_n of_o opium_n but_o that_o the_o want_n of_o a_o few_o experiment_n have_v to_o my_o grief_n hitherto_o delay_v it_o and_o therefore_o i_o must_v be_v put_v to_o much_o trouble_v in_o this_o work_n for_o want_v thereof_o because_o i_o be_o resolve_v not_o to_o spare_v myself_o in_o order_n to_o satisfy_v the_o reader_n in_o this_o great_a and_o unexplicate_v mystery_n 2._o if_o vapour_n be_v the_o cause_n of_o natural_a sleep_n it_o be_v impossible_a that_o the_o prick_n of_o a_o pin_n or_o a_o sharp_a sound_n etc._n etc._n shall_v awake_v one_o ten_o or_o twenty_o time_n in_o a_o hour_n for_o either_o the_o prick_n must_v in_o a_o instant_n discuss_v all_o the_o fume_n in_o be_v which_o be_v impossible_a to_o be_v imagine_v and_o they_o as_o often_o return_v to_o cause_n sleep_v again_o or_o intercept_v their_o motion_n from_o the_o stomach_n to_o the_o head_n which_o no_o man_n can_v have_v any_o conception_n of_o the_o efficacy_n of_o the_o pin_n or_o sound_v so_o to_o do_v or_o they_o must_v both_o discuss_v and_o intercept_v the_o fume_n which_o indeed_o if_o the_o case_n be_v such_o will_v be_v necessary_a to_o make_v a_o clear_a awake_v which_o be_v yet_o far_o more_o unconceivable_a what_o paltry_a trifle_n do_v the_o world_n embrace_v instead_o of_o truth_n and_o reason_n 3._o several_a person_n whereof_o i_o be_o one_o do_v awake_a in_o a_o minute_n or_o two_o after_o they_o first_o fall_v asleep_a in_o bed_n at_o night_n which_o will_v be_v absolute_o impossible_a if_o fume_n cause_v sleep_n for_o the_o fume_n will_v
of_o it_o and_o what_o be_v to_o be_v say_v thereof_o more_o at_o large_a hereafter_o i_o say_v then_o that_o hot_a spirituous_a cordial_n for_o such_o indeed_o all_o proper_a cordial_n be_v as_o brandy_n dr._n stephens_n water_n and_o suchlike_a have_v sulphureous_a particle_n so_o prepare_v and_o dispose_v towards_o heat_n or_o fire_n that_o they_o be_v as_o it_o be_v in_o potentia_fw-la proxima_fw-la or_o next_o disposition_n thereto_o be_v mighty_a apt_a to_o contract_v a_o heat_n as_o you_o find_v by_o spirit_n of_o wine_n or_o brandy_n keep_v the_o least_o time_n in_o a_o warm_a place_n or_o to_o come_v close_o to_o the_o matter_n in_o your_o mouth_n wherein_o be_v actuate_v by_o its_o heat_n they_o will_v as_o in_o a_o instant_n grow_v so_o hot_a and_o active_a that_o you_o can_v hardly_o bear_v they_o because_o particle_n of_o heat_n which_o penetrate_v any_o metal_n glass_n etc._n etc._n immediate_o as_o soon_o as_o apply_v thereto_o will_v much_o more_o easy_o and_o soon_o penetrate_v our_o soft_a part_n at_o mouth_n or_o the_o crusta_fw-la carnosa_fw-la at_o stomach_n and_o so_o reach_v the_o most_o sensile_a coat_n thereof_o please_v comfort_a and_o exciting_a the_o spiritus_fw-la insitos_fw-la as_o in_o a_o moment_n by_o their_o spirituous_a heat_n which_o we_o actual_o feel_v and_o sensible_o find_v to_o please_v and_o comfort_v the_o stomach_n but_o if_o some_o purge_v tincture_n have_v be_v put_v into_o the_o cordial_n or_o brandy_n this_o will_v not_o have_v soak_v through_o the_o crusta_fw-la carnosa_fw-la under_o some_o time_n and_o consequent_o not_o operate_v till_o it_o have_v this_o may_v be_v most_o manifest_o illustrate_v by_o some_o hot_a brandy_n or_o indeed_o any_o hot_a liquid_a put_v into_o a_o porous_a dish_n set_v upon_o one_o hand_n which_o present_o warm_v it_o but_o if_o the_o liquid_a be_v tinge_v with_o any_o thing_n that_o tincture_n will_v not_o reach_v the_o hand_n till_o the_o liquor_n which_o be_v its_o vehicle_n soak_v through_o which_o may_v be_v in_o a_o hour_n more_o or_o less_o according_a to_o the_o porosity_n of_o the_o wood_n which_o tincture_n be_v to_o be_v compare_v to_o the_o purgative_n at_o stomach_n hence_o it_o follow_v that_o all_o cordial_n shall_v be_v a_o spirituous_a liquid_a if_o intend_v for_o sudden_a refreshment_n which_o experience_n have_v teach_v and_o be_v give_v actual_o warm_v if_o a_o very_a nimble_a comfort_n be_v require_v though_o the_o great_a heat_n of_o the_o stomach_n above_o that_o of_o the_o mouth_n will_v general_o be_v sufficient_a thus_o may_v the_o stomach_n be_v please_v and_o comfort_v grieve_v and_o purge_v with_o the_o same_o draught_n but_o gracious_a providence_n have_v give_v the_o start_n to_o the_o cordial_n which_o immediate_o comfort_v we_o as_o a_o heater_n 30._o if_o opium_n operate_v by_o such_o fume_n it_o will_v at_o least_o in_o a_o liquid_a form_n begin_v its_o operation_n as_o soon_o as_o it_o be_v at_o stomach_n for_o it_o will_v begin_v to_o send_v up_o fume_n as_o soon_o as_o it_o begin_v to_o be_v warm_a which_o be_v present_o and_o be_v at_o a_o very_a considerable_a height_n of_o fume_v and_o consequent_o of_o operation_n in_o one_o minute_n which_o be_v about_o the_o space_n of_o seventy_o ordinary_a pulse_n but_o we_o do_v not_o find_v it_o begin_v to_o operate_v in_o that_o form_n under_o twenty_o thirty_o or_o forty_o minute_n which_o be_v much_o about_o the_o time_n that_o a_o more_o agreeable_a and_o not_o nauseated_a vomitive_a or_o purger_n begin_v to_o affect_v the_o sensile_a coat_n of_o the_o stomach_n and_o give_v intimation_n of_o their_o so_o do_v all_o which_o and_o the_o sense_n of_o pleasure_n that_o we_o actual_o then_o seel_v at_o stomach_n make_v it_o probable_a that_o it_o operate_v by_o affect_v the_o stomach_n pleasant_o and_o comfortable_o after_o the_o manner_n of_o generous_a wine_n as_o purger_n and_o vomatives_n do_v by_o affect_v it_o grievous_o all_o of_o they_o except_o the_o wine_n that_o please_v and_o comfort_v soon_o because_o of_o its_o particle_n of_o heat_n gain_v by_o fermentation_n operate_a much_o in_o the_o same_o time_n because_o they_o take_v like_o leisure_n to_o soak_v through_o the_o crusta_fw-la carnosa_fw-la to_o the_o sensile_a coat_n of_o the_o stomach_n 31._o all_o sensitive_a pleasure_n comfort_n etc._n etc._n be_v receive_v by_o the_o sense_n and_o though_o any_o part_n be_v some_o way_n benefit_v that_o have_v no_o sense_n no_o comfort_n will_v be_v perceive_v without_o perception_n none_o can_v say_v that_o he_o be_v comfort_v what_o fit_a part_n be_v there_o to_o be_v please_v and_o comfort_v by_o sensation_n than_o the_o stomach_n which_o have_v such_o exquisite_a sense_n that_o it_o can_v discern_v the_o vomitory_n particle_n in_o infusion_n of_o the_o grocus_n or_o regulus_n of_o antimony_n which_o no_o sensation_n but_o that_o at_o stomach_n can_v discern_v and_o so_o small_a that_o a_o thousand_o vomitory_n make_v thereof_o by_o infusion_n do_v not_o sensible_o diminish_v the_o grocus_n or_o regulus_n as_o to_o weight_n or_o bulk_n nor_o can_v i_o conceive_v where_o any_o sensible_a comfort_n can_v be_v perceive_v by_o a_o spoonful_n of_o cordial_n but_o at_o stomach_n where_o it_o actual_o be_v and_o upon_o who_o coat_n it_o immediate_o insist_o be_v it_o not_o there_o that_o we_o feel_v the_o comfort_n and_o where_o shall_v we_o find_v it_o but_o there_o what_o will_v the_o effluvium_n of_o a_o spoonful_n signify_v if_o mix_v with_o 100000_o time_n as_o much_o insensile_a blood_n and_o what_o part_n beside_o the_o stomach_n that_o the_o blood_n touch_v can_v be_v sensible_a of_o it_o so_o that_o if_o effluvium_n be_v grant_v it_o be_v thither_o they_o must_v return_v to_o cause_v any_o considerable_a pleasure_n or_o comfort_n but_o what_o need_v any_o reâ—urn_n of_o the_o inconsiderable_a effluvia_fw-la when_o the_o main_a body_n of_o the_o cordial_n yea_o all_z lie_v upon_o the_o stomach_n already_o i_o must_v forbear_v run_v into_o the_o business_n of_o other_o chapter_n have_v be_v tedious_a enough_o upon_o the_o subject_a of_o this_o and_o the_o rather_o because_o it_o be_v so_o general_a and_o so_o root_v a_o opinion_n in_o the_o mind_n of_o man_n in_o all_o age_n and_o in_o all_o sect_n of_o physician_n and_o natural_a philosopher_n that_o i_o can_v not_o say_v too_o much_o to_o endeavour_v to_o free_v the_o world_n from_o the_o slavery_n of_o such_o a_o imposition_n and_o the_o innumerable_a ill_a consequence_n of_o such_o a_o fundamental_a and_o overgrow_a error_n which_o certain_o must_v have_v be_v long_o since_o explode_v if_o ingenious_a man_n have_v first_o think_v and_o then_o speak_v free_o but_o the_o truth_n be_v there_o be_v many_o and_o great_a cause_n to_o the_o contrary_a as_o those_o intimate_v in_o the_o last_o paragraph_n and_o the_o mighty_a usefulness_n and_o ready_a officiousness_n of_o that_o opinion_n of_o fume_n to_o answer_v for_o all_o the_o more_o obscure_a and_o latent_fw-la cause_n of_o the_o malady_n and_o disaster_n of_o the_o brain_n and_o genus_fw-la nervosum_fw-la if_o any_o inquire_v or_o call_v for_o the_o cause_n of_o a_o vertigo_n the_o physician_n answer_v fume_n of_o epilepsy_n it_o be_v answer_v fume_n of_o scotomy_n it_o be_v fume_n of_o headache_n migraine_n coma_n caros_n lethargy_n etc._n etc._n it_o be_v fume_n of_o hysterick_n fit_n convulsion_n spasm_n cramp_n etc._n etc._n it_o be_v fume_n nay_o they_o answer_v as_o cause_n to_o all_o distillation_n catarrh_n epiphora_n or_o weep_v eye_n and_o all_o even_o ordinary_a tear_n all_o which_o they_o say_v be_v only_o these_o fume_n turn_v into_o water_n by_o the_o coldness_n of_o the_o brain_n as_o they_o be_v in_o a_o still_o or_o alembick_a so_o hot_a fume_n account_v for_o frenzy_n delirium_n rave_n etc._n etc._n so_o that_o however_o other_o head_n be_v the_o physician_n be_v be_v stuff_v therewith_o and_o all_o meteor_n of_o the_o microcosm_n upper_a region_n whether_o hot_a or_o cold_a be_v as_o those_o in_o the_o macrocosm_n form_v out_o of_o fume_n as_o he_o imagine_v thus_o you_o see_v all_o the_o opinion_n and_o hypothesise_n that_o have_v be_v concern_v the_o operation_n of_o opium_n to_o be_v most_o absurd_a and_o direct_o contrary_a to_o all_o sense_n reason_n and_o experience_n chap._n xi_o opium_n do_v not_o diminish_v or_o disable_v the_o spirit_n by_o any_o mean_n whatsoever_o have_v sufficient_o demonstrate_v that_o opium_n can_v diminish_v or_o disable_v the_o spirit_n by_o the_o cold_a quality_n of_o the_o ancient_n or_o fume_n of_o the_o modern_n and_o that_o neither_o of_o they_o have_v as_o much_o as_o any_o be_v i_o shall_v now_o add_v that_o opium_n do_v not_o diminish_v or_o disable_v the_o spirit_n by_o any_o other_o mean_n whatsoever_o i_o will_v not_o be_v mistake_v when_o i_o say_v that_o opium_n do_v not_o diminish_v or_o disable_v
the_o spirit_n by_o any_o mean_n for_o there_o be_v nothing_o so_o good_a in_o nature_n but_o will_v do_v it_o if_o use_v undue_o or_o immoderate_o as_o wine_n bread_n milk_n honey_n sugar_n beer_n etc._n etc._n in_o excess_n for_o i_o intend_v that_o it_o do_v not_o do_v it_o when_o due_o and_o moderate_o use_v 1._o that_o which_o refresh_v the_o weary_a and_o high_o prevent_v weariness_n must_v add_v to_o or_o excite_v the_o spirit_n which_o be_v direct_o contrary_a to_o diminish_v or_o disable_n they_o but_o opium_n do_v in_o a_o most_o eminent_a manner_n refresh_v the_o weary_v and_o prevent_v weariness_n therefore_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n some_o have_v be_v so_o silly_a and_o inadvertent_n as_o to_o object_n that_o it_o refresh_v the_o weary_a only_o by_o sleep_n it_o be_v matter_n of_o fact_n that_o it_o refresh_v they_o whether_o they_o sleep_v or_o no_o and_o that_o without_o fail_v as_o often_o as_o it_o be_v use_v in_o that_o case_n other_o that_o be_v no_o wise_a have_v say_v that_o it_o only_o take_v off_o the_o sense_n of_o weariness_n by_o stupify_a which_o happen_v by_o the_o diminish_n or_o disable_n of_o the_o animal_n spirit_n bare_a insensibleness_n can_v enable_v the_o spirit_n to_o labour_n with_o eminent_a briskness_n and_o alacrity_n as_o man_n most_o certain_o do_v after_o opium_n be_v take_v be_v fine_o enliven_v and_o invigorate_v as_o with_o generous_a wine_n if_o they_o do_v not_o know_v this_o to_o be_v true_a let_v they_o for_o shame_n hold_v their_o tongue_n till_o they_o know_v matter_n of_o fact_n which_o if_o they_o will_v not_o they_o proclaim_v themselves_o to_o be_v idle_a and_o impertinent_a babbler_n but_o if_o they_o will_v patient_o and_o wise_o abstain_v argue_v till_o they_o be_v satisfy_v as_o to_o matter_n of_o fact_n then_o will_v they_o be_v past_a opinion_n and_o hypothesis_n in_o that_o case_n for_o they_o will_v have_v sensible_a and_o certain_a knowledge_n of_o the_o contrary_a and_o the_o truth_n of_o what_o i_o say_v which_o will_v end_v all_o controversy_n and_o precarious_a squabble_n upon_o false_a supposition_n as_o the_o manner_n be_v that_o can_v lead_v they_o to_o what_o be_v right_o but_o by_o mere_a chance_n and_o never_o to_o a_o true_a knowledge_n that_o they_o be_v in_o the_o right_n which_o make_v it_o none_o in_o effect_n for_o they_o can_v do_v nothing_o with_o assurance_n but_o only_o suppose_v and_o hope_v they_o be_v in_o the_o right_n when_o they_o be_v as_o much_o out_o to_o their_o patient_n sorrow_n as_o physician_n have_v be_v in_o the_o cold_a quality_n and_o fume_n of_o opium_n it_o be_v true_a that_o a_o grain_n or_o two_o of_o opium_n will_n if_o a_o man_n compose_v himself_o sit_v or_o lie_v still_o cause_n a_o sleepiness_n equal_a to_o that_o cause_v by_o spend_v the_o spirit_n by_o a_o day_n be_v labour_n but_o spend_v of_o the_o spirit_n be_v not_o the_o only_a no_o nor_o best_a proportion_v or_o more_o adequate_a cause_n thereof_o as_o i_o have_v show_v if_o loss_n of_o spirit_n be_v the_o adequate_a cause_n of_o sleep_n how_o shall_v good_a and_o generous_a wine_n cause_n sleepiness_n after_o that_o eminent_a rate_n as_o it_o do_v in_o most_o people_n how_o shall_v the_o most_o please_a music_n incline_v such_o as_o lie_v or_o sit_v still_o to_o sleep_v but_o if_o one_o dance_n thereto_o it_o make_v he_o more_o lively_a and_o brisk_a than_o ordinary_a the_o like_a exact_o do_v wine_n and_o opium_n if_o man_n lie_v or_o sit_v still_o but_o otherwise_o they_o make_v they_o much_o more_o brisk_a and_o lively_a and_o able_a to_o undergo_v labour_n action_n etc._n etc._n which_o note_n that_o you_o may_v not_o any_o more_o wonder_n that_o enlivener_n and_o exciter_n of_o the_o spirit_n do_v cause_n sleep_v as_o well_o as_o diminisher_n thereof_o and_o observe_v that_o they_o be_v all_o please_a thing_n as_o music_n wine_n and_o opium_n which_o cause_n pleasant_a dream_n pleasant_a watch_n pleasant_a humour_n etc._n etc._n expect_v more_o of_o this_o matter_n in_o the_o follow_a chapter_n and_o all_o by_o degree_n according_a as_o i_o judge_v the_o prejudice_v world_n will_v bear_v thing_n for_o a_o great_a paradox_n how_o true_a soever_o must_v not_o be_v abrupt_o obtrude_v but_o gentle_o and_o gradual_o usher_v in_o by_o insinuate_v reason_v otherwise_o it_o will_v be_v entertain_v like_o a_o rude_a stranger_n that_o contradict_v a_o multitude_n in_o fashion_n and_o custom_n that_o they_o have_v always_o use_v and_o judge_v to_o be_v the_o very_o best_o however_o unblamable_a consider_v that_o if_o opium_n diminish_v or_o disable_v the_o spirit_n proportionable_a to_o the_o sleepiness_n that_o it_o cause_n as_o a_o hard_a day_n be_v labour_n do_v then_o if_o opium_n be_v give_v a_o man_n after_o a_o hard_a day_n be_v labour_n it_o will_v be_v as_o it_o be_v add_v another_o hard_a day_n be_v labour_v to_o cure_v it_o the_o day_n be_v labour_n and_o opium_n impair_n the_o spirit_n alike_o think_v what_o a_o miserable_a condition_n the_o poor_a man_n will_v be_v in_o especial_o if_o sleep_n do_v not_o make_v he_o some_o amends_o it_o will_v be_v such_o as_o be_v utter_o intolerable_a but_o so_o far_o be_v opium_n from_o any_o such_o effect_n that_o it_o refresh_v he_o though_o he_o sleep_v not_o at_o all_o after_o the_o hard_a day_n be_v labour_n and_o not_o only_o so_o but_o will_v enable_v he_o to_o work_v all_o the_o follow_a night_n with_o great_a alacrity_n if_o need_n require_v it_o what_o a_o condition_n will_v those_o be_v in_o who_o take_v a_o drachm_n of_o it_o twice_o a_o day_n for_o 10_o 20_o or_o 30_o year_n nay_o how_o can_v any_o possible_o do_v it_o for_o half_a 10_o day_n if_o a_o grain_n or_o two_o destroy_v the_o spirit_n so_o much_o as_o to_o cause_v sleepiness_n thereby_o as_o hard_a labour_n do_v which_o they_o must_v allow_v that_o assert_v it_o cause_n sleep_v by_o diminish_v or_o disable_n the_o spirit_n but_o some_o may_v say_v though_o very_o inconsiderate_o that_o it_o only_o disable_v they_o for_o the_o time_n of_o its_o operation_n that_o be_v strange_a indeed_o consider_v that_o even_o during_o that_o time_n they_o be_v most_o enable_v to_o work_n or_o labour_n though_o tire_v before_o and_o that_o it_o 2._o cause_n comfort_n refreshment_n ovation_n of_o the_o spirit_n all_o the_o time_n of_o its_o operation_n as_o wine_n moderate_o take_v do_v especial_o if_o people_n keep_v themselves_o in_o action_n labour_n etc._n etc._n otherwise_o indeed_o they_o may_v fall_v asleep_a upon_o the_o comfortable_a satisfaction_n contentation_n of_o mind_n and_o acquiescence_n of_o spirit_n that_o it_o occasion_n as_o wine_n do_v 3._o the_o first_o effect_n that_o we_o find_v of_o opium_n which_o may_v therefore_o probable_o be_v a_o very_a lead_n fundamental_a and_o significant_a effect_n be_v that_o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o incline_v he_o to_o sleep_n if_o not_o it_o make_v he_o gay_a good_a humour_a brave_a etc._n etc._n it_o be_v a_o pleasure_n so_o sweet_a and_o delicious_a that_o though_o i_o endeavour_v to_o express_v it_o by_o the_o ovation_n of_o the_o spirit_n upon_o joy_n a_o good_a genius_n inform_v a_o man_n or_o the_o helmâ—sians_n archaeus_n in_o his_o best_a humour_n or_o a_o continual_a vâ—real_a pleasure_n wine_n drink_v ad_fw-la hilaritatem_fw-la etc._n etc._n yet_o i_o doubt_v all_o my_o way_n of_o express_v it_o do_v come_v short_a of_o the_o charm_a complacency_n that_o it_o cause_n therefore_o if_o wine_n music_n a_o good_a meal_n agreeable_a frication_n of_o the_o head_n or_o back_o the_o sound_n of_o water_n etc._n etc._n do_v incline_v we_o to_o sleep_v by_o the_o pleasure_n thereof_o which_o lull_v and_o soothe_v we_o to_o it_o as_o be_v most_o certain_a if_o we_o sit_v or_o lie_v still_o much_o more_o must_v the_o high_a charm_n of_o opium_n cause_n it_o that_o it_o be_v a_o pleasure_n that_o affect_v by_o one_o of_o our_o sense_n namely_o by_o feel_v be_v indisputable_a for_o it_o be_v not_o a_o pleasure_n of_o the_o eye_n nose_n tongue_n or_o ear_n and_o it_o must_v be_v sensitive_a because_o cause_v by_o matter_n and_o that_o opium_n have_v doubtless_o the_o like_a effect_n upon_o brute_n who_o have_v no_o other_o pleasure_n but_o what_o be_v sensitive_a that_o it_o be_v at_o stomach_n be_v also_o evident_a where_o we_o can_v be_v please_v only_o by_o the_o sense_n of_o feel_v that_o it_o be_v involuntary_a and_o please_v we_o whether_o we_o will_v or_o no_o and_o that_o the_o same_o particle_n excite_v venery_n itch_a etc._n etc._n now_o all_o the_o sense_n especial_o feel_v and_o particular_o that_o at_o stomach_n be_v give_v we_o for_o
sensation_n of_o the_o sensile_a part_n which_o can_v well_o happen_v in_o that_o sound_a sleep_n wherein_o there_o be_v so_o little_a feel_v by_o reason_n of_o the_o say_a relaxation_n and_o because_o relaxation_n oppose_v contraction_n by_o which_o that_o shiver_a be_v promote_v such_o a_o relaxation_n and_o failure_n of_o feel_v thereupon_o be_v the_o true_a cause_n why_o opium_n put_v off_o ague_n fit_n etc._n etc._n so_o 20._o the_o relaxation_n in_o sleep_n stop_v vomit_v by_o take_v away_o the_o sense_n of_o the_o irritate_v cause_n and_o quiet_v as_o i_o have_v intimate_v all_o motion_n in_o general_a so_o sleep_v stop_n hiccough_n hemorrhage_n diary_n fever_n etc._n etc._n 21._o why_o watch_v labour_n or_o what_o impair_v the_o spirit_n and_o tire_v the_o sensitive_a soul_n incline_v we_o to_o sleep_v that_o be_v dispose_v the_o sensitive_a soul_n the_o only_a feeler_n of_o lassitude_n to_o give_v over_o contract_n the_o sensile_a part_n which_o as_o will_v plain_o appear_v by_o and_o by_o spend_v the_o spirit_n as_o sleep_v by_o relax_v they_o cause_v a_o recruit_v thereof_o to_o be_v short_a though_o one_o can_v hardly_o be_v too_o long_o in_o solve_v phenomena_n which_o be_v the_o proof_n of_o the_o truth_n of_o a_o man_n assertion_n the_o mechanical_a demonstration_n that_o i_o have_v make_v of_o the_o state_n of_o sleep_v and_o wake_v do_v so_o evident_o explicate_v all_o the_o phenomena_n of_o both_o that_o i_o be_o even_o ashamed_a to_o run_v any_o far_o upon_o such_o plain_a matter_n so_o obvious_a be_v thing_n when_o the_o truth_n be_v know_v and_o therefore_o have_v mention_v those_o circumstance_n and_o effect_n of_o sleep_n that_o main_o concern_v we_o i_o must_v give_v over_o lest_o the_o world_n shall_v think_v that_o i_o take_v all_o my_o reader_n to_o be_v idiot_n by_o use_v too_o many_o word_n in_o so_o obvious_a a_o thing_n or_o that_o i_o be_o no_o better_o for_o use_v they_o without_o cause_n for_o the_o truth_n of_o this_o matter_n seem_v to_o i_o to_o outshine_v all_o the_o argument_n i_o can_v make_v for_o it_o such_o splendour_n do_v truth_n show_v upon_o the_o first_o glimpse_n thereof_o as_o i_o take_v the_o account_n i_o give_v of_o sleep_n and_o watch_v to_o be_v for_o the_o opinion_n i_o have_v meet_v concern_v they_o be_v quite_o contrary_a to_o or_o very_o remote_a from_o what_o i_o have_v state_v 1._o they_o go_v quite_o contrary_a to_o it_o that_o say_v that_o the_o animal_n spirit_n be_v expanded_a and_o the_o pore_n of_o the_o brain_n etc._n etc._n more_o open_a and_o consequent_o more_o lax_n in_o watch_v as_o willis_n and_o several_a other_o who_o therefore_o say_v that_o coffee_n volatile_a salt_n etc._n etc._n be_v antihypnotick_n or_o good_a against_o too_o much_o sleepiness_n because_o they_o cause_v a_o expansion_n of_o the_o spirit_n and_o open_v the_o pore_n of_o the_o brain_n suppose_v forsooth_o that_o they_o march_v up_o and_o down_o and_o so_o keep_v the_o great_a stir_n upon_o the_o false_a imagination_n of_o their_o road_n be_v more_o open_a which_o as_o be_v prove_v be_v real_o more_o close_a coffee_n keep_v we_o from_o sleep_n by_o dry_v bind_a and_o both_o way_n constr_v the_o vessel_n as_o also_o by_o a_o wide_a grate_a quality_n which_o therefore_o do_v irritate_fw-la they_o to_o contract_v beside_o that_o the_o saline_n particle_n cause_v a_o agitation_n may_v contribute_v thereto_o so_o that_o by_o constr_v and_o agitate_v it_o direct_o oppose_v sleep_n which_o proceed_v from_o relaxation_n and_o quietness_n 2._o they_o be_v very_o remote_a from_o the_o mark_n that_o say_v as_o wedeliâ—s_a assert_n all_o do_v that_o vapour_n be_v the_o cause_n of_o natural_a sleep_n which_o bear_v no_o manner_n of_o proportion_n thereto_o as_o be_v show_v as_o they_o be_v also_o who_o mâ—dly_o talk_v that_o the_o animal_n spirit_n which_o have_v neither_o life_n sense_n motion_n or_o election_n do_v of_o themselves_o retire_v very_o know_o to_o the_o brain_n in_o sâ—eep_n and_o leave_v the_o limb_n etc._n etc._n destitute_a of_o they_o whereas_o as_o have_v be_v mechanical_o prove_v they_o have_v more_o room_n than_o that_o at_o other_o time_n in_o 〈◊〉_d limb_n and_o all_o the_o sensile_a part_n but_o i_o will_v not_o argue_v against_o such_o senseless_a and_o precarious_a absurdity_n it_o be_v not_o worth_a the_o while_n especial_o since_o the_o truth_n be_v manifest_o discover_v it_o will_v not_o have_v be_v so_o silly_a to_o have_v affirm_v the_o quite_o contrary_a viz._n that_o the_o animal_n spirit_n be_v force_v into_o the_o soft_a and_o yield_a brain_n in_o watch_v by_o the_o vigilative_a contraction_n of_o all_o the_o senfile_v part_n repel_v they_o as_o when_o cold_a repel_v they_o by_o a_o strong_a contraction_n of_o the_o part_n and_o cause_v a_o stupor_n or_o sleep_n thereof_o as_o they_o call_v it_o but_o what_o have_v we_o to_o do_v with_o such_o insufferable_a trash_n therefore_o bid_v it_o adieu_n let_v we_o pursue_v our_o business_n that_o it_o be_v the_o sensitive_a soul_n and_o nothing_o but_o it_o have_v that_o contract_n power_n be_v evident_a 1._o because_o it_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n as_o such_o and_o that_o nothing_o beside_o it_o have_v any_o life_n perception_n motion_n or_o power_n and_o therefore_o must_v rest_v till_o they_o be_v move_v 2._o because_o that_o when_o the_o sensitive_a soul_n be_v divert_v by_o intense_a pleasure_n from_o attend_v his_o business_n immediate_o relaxation_n follow_v as_o in_o the_o pleasure_n of_o the_o act_n of_o venery_n by_o wine_n joy_n etc._n etc._n in_o which_o you_o have_v all_o the_o effect_n of_o relaxation_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la plentiful_a perspiration_n floridity_n of_o the_o skin_n a_o large_a pulse_n and_o sometime_o a_o considerable_a failure_n of_o sense_n and_o motion_n as_o in_o the_o most_o pleasant_a time_n of_o the_o venereal_a act_n deliquiums_n drunkenness_n syncopes_fw-la or_o ecstasy_n upon_o intense_a pleasure_n which_o be_v very_o proper_o call_v ecstasy_n leipothymy_n leipopsychy_n etc._n etc._n which_o signify_v the_o soul_n leave_v we_o without_o his_o help_n by_o contraction_n which_o he_o then_o do_v not_o exercise_n as_o be_v charm_v and_o whole_o take_v up_o with_o pleasure_n this_o be_v the_o true_a cause_n of_o all_o deliquium_n etc._n etc._n upon_o pleasure_n joy_n etc._n etc._n all_o which_o cause_n great_a relaxation_n and_o thereby_o loss_n of_o sense_n and_o motion_n as_o be_v its_o necessary_a consequence_n 3._o because_o grievous_a sensation_n which_o belong_v only_o to_o the_o sensitive_a soul_n put_v we_o immediate_o out_o of_o sleep_n into_o a_o vigilative_a contraction_n 4._o because_o the_o sensitive_a soul_n can_v when_o we_o be_v sleepy_a oppose_v it_o by_o continue_v the_o vigilative_a contraction_n which_o prove_v vigilative_a contraction_n to_o be_v in_o his_o power_n note_v that_o there_o be_v also_o other_o sort_n of_o leipothymy_n deliquium_n etc._n etc._n upon_o the_o sensitive_a soul_n be_v overtired_n whereof_o natural_a sleep_n be_v but_o a_o common_a and_o ordinary_a degree_n that_o happen_v of_o course_n for_o our_o relief_n or_o overbear_v with_o some_o fatigue_n etc._n etc._n as_o when_o somewhat_o grieve_v at_o stomach_n and_o that_o it_o have_v lay_v about_o it_o all_o manner_n of_o way_n by_o vomit_v convulsive_a motion_n etc._n etc._n to_o be_v rid_v of_o it_o till_o it_o can_v work_v no_o long_o whereupon_o it_o lay_v down_o the_o cudgel_n desi_v from_o all_o further_a endeavour_n by_o contraction_n yield_v itself_o to_o ease_n see_v all_o strive_v be_v to_o no_o effect_n so_o that_o though_o this_o deliquium_fw-la and_o the_o former_a differ_v in_o their_o first_o cause_n yet_o do_v they_o agree_v in_o the_o last_o and_o immediate_a viz._n the_o sensitive_a soul_n be_v not_o attend_v his_o business_n of_o contraction_n whereupon_o follow_v a_o mighty_a relaxation_n as_o appear_v by_o the_o deadness_n or_o relaxation_n of_o the_o cornea_n dilatation_n of_o the_o pupil_n a_o great_a laxity_n of_o all_o part_n a_o large_a pulse_n or_o none_o very_o plentiful_a perspiration_n stop_v of_o hemorrhage_n and_o all_o flux_n that_o require_v contraction_n etc._n etc._n which_o happen_v both_o upon_o the_o account_n of_o the_o great_a relaxation_n itself_o as_o have_v be_v show_v and_o the_o almost_o absolute_a rest_n of_o all_o thing_n by_o the_o sensitive_a soul_n withdraw_a himself_n from_o business_n more_o than_o in_o sleep_n itself_o i_o therefore_o observe_v the_o degree_n of_o sleep_n etc._n etc._n do_v note_n that_o god_n and_o nature_n use_v a_o due_a proportion_n in_o all_o thing_n the_o sensitive_a soul_n use_v several_a degree_n of_o relaxation_n according_a as_o he_o be_v tire_v and_o refection_n be_v want_v hence_o it_o be_v that_o such_o as_o be_v much_o tire_v sleep_n more_o profound_o that_o our_o first_o
titillation_n and_o actuate_a of_o our_o spirit_n nor_o too_o full_a of_o volatile_a salt_n as_o mustard_n asarabacca_n etc._n etc._n nor_o have_v too_o accrimonious_a a_o volatile_a salt_n with_o too_o little_a oleous_a part_n to_o correct_v it_o for_o in_o both_o these_o last_o case_n the_o irritation_n will_v be_v grievous_a nor_o have_v the_o oleous_a and_o volatile_a loose_o combine_v but_o that_o it_o shall_v be_v a_o sal_fw-la volatile_a oleosum_fw-la wherein_o the_o volatile_a part_n be_v brisk_a and_o somewhat_o more_o active_a than_o we_o yet_o so_o correct_v by_o oleous_a part_n intimate_o combine_v therewith_o as_o to_o render_v it_o of_o a_o most_o agreeable_a and_o pleasant_a titillation_n such_o as_o will_v please_v all_o membrane_n but_o especial_o those_o that_o have_v most_o acute_a sensation_n as_o the_o stomach_n and_o venereal_a membrane_n both_o which_o opium_n most_o sensible_o please_v which_o be_v order_v so_o to_o be_v for_o preservation_n of_o the_o individuum_fw-la and_o species_n the_o one_o to_o invite_v we_o to_o eat_v and_o the_o other_o to_o procreate_v but_o to_o satisfy_v you_o yet_o far_o as_o to_o the_o stomach_n which_o concern_v we_o most_o note_v 1._o that_o the_o more_o exalt_v and_o intense_a the_o pleasure_n be_v the_o high_a be_v its_o effect_n upon_o the_o sensitive_a soul_n in_o please_v comfort_a and_o elevate_a it_o and_o upon_o the_o body_n in_o relax_v all_o the_o sensile_a part_n thereof_o as_o that_o of_o wine_n be_v high_a than_o that_o of_o mustum_fw-la etc._n etc._n note_v 2._o that_o the_o better_a the_o organ_n be_v dispose_v for_o sensation_n the_o high_a the_o pleasure_n or_o displeasure_n be_v for_o he_o that_o have_v his_o nose_n tongue_n ear_n membrane_n etc._n etc._n ill_o dispose_v for_o smell_a taste_v hear_v feel_v etc._n etc._n have_v not_o so_o much_o pleasure_n in_o sweet_a odour_n good_a taste_n music_n pleaser_n of_o the_o feel_n etc._n etc._n nor_o so_o much_o displeasure_n in_o bad_a scent_n etc._n etc._n it_o follow_v note_v 3_o that_o cujus_fw-la est_fw-la dolour_n ejusdem_fw-la est_fw-la voluptas_fw-la that_o be_v the_o part_n or_o membrane_n that_o be_v capable_a of_o intense_a pleasure_n be_v so_o of_o intense_a pain_n or_o displeasure_n for_o instance_n if_o the_o stomach_n be_v capable_a of_o great_a grievance_n it_o be_v so_o of_o great_a pleasure_n god_n have_v distribute_v they_o also_o equal_o note_v 4._o that_o since_o the_o great_a use_n end_v and_o business_n of_o sensation_n be_v to_o give_v notice_n and_o inform_v the_o animal_n of_o what_o be_v or_o be_v not_o good_a and_o agreeable_a to_o it_o it_o follow_v that_o the_o wisdom_n that_o make_v we_o will_v place_v the_o most_o exquisite_o and_o critical_o dispose_v organ_n or_o membrane_n of_o sensation_n where_o such_o notice_n be_v most_o requisite_a and_o useful_a and_o consequent_o there_o must_v be_v more_o pleasure_n or_o displeasure_n conceive_v at_o thing_n agreeable_a or_o disagreeable_a that_o the_o descend_v and_o relieve_v motion_n and_o comfort_n may_v be_v proportionable_a note_v 5._o that_o such_o exquisite_a exact_a and_o nice_a notice_n be_v most_o requisite_a at_o stomach_n first_o because_o all_o our_o nutriment_n good_a and_o bad_a be_v to_o pass_v that_o way_n to_o be_v judge_v of_o second_o because_o it_o be_v the_o last_o part_n that_o it_o arrive_v at_o before_o it_o receive_v a_o considerable_a change_n for_o when_o it_o be_v change_v no_o such_o true_a and_o sincere_a judgement_n can_v be_v give_v thereof_o as_o can_v be_v before_o three_o because_o the_o fault_n defect_n or_o negligence_n of_o the_o taste_n and_o the_o external_n sense_n be_v to_o be_v remedy_v and_o correct_v there_o or_o no_o where_o therefore_o the_o stomach_n be_v as_o the_o last_o judge_n of_o appeal_n and_o shall_v be_v most_o exact_a and_o infallible_a in_o judge_v or_o as_o the_o last_o inner_a or_o main_a guard_n in_o a_o fort_n town_n or_o castle_n which_o if_o the_o enemy_n pass_v the_o whole_a be_v endanger_v if_o not_o lose_v four_o because_o the_o concern_v be_v so_o great_a sensation_n shall_v be_v the_o more_o exquisite_a there_o to_o excite_v the_o animal_n power_n to_o make_v defence_n by_o repel_v reject_v or_o detrude_a the_o enemy_n which_o power_n as_o have_v be_v intimate_v be_v excite_v according_a to_o the_o degree_n of_o sensation_n especial_o see_v there_o be_v no_o voluntary_a power_n or_o contraction_n of_o the_o stomach_n but_o only_o the_o natural_a which_o be_v always_o excite_v by_o sensation_n in_o such_o case_n or_o not_o at_o all_o five_o sensation_n shall_v be_v critical_a and_o accurate_a at_o stomach_n to_o inform_v we_o precise_o when_o we_o shall_v eat_v or_o drink_v six_o to_o inform_v we_o exact_o when_o we_o have_v eat_v or_o drink_v enough_o for_o all_o this_o be_v do_v by_o sensation_n therefore_o god_n have_v place_v a_o most_o sensile_a membrane_n at_o the_o stomach_n as_o most_o manifest_o appear_v first_o by_o its_o take_n and_z giving_z notice_n of_o such_o minute_n thing_n that_o no_o sense_n part_n organ_n or_o membrane_n can_v for_o it_o take_v notice_n of_o and_o inform_v the_o sensitive_a soul_n as_o have_v be_v say_v of_o the_o vomitory_n particle_n of_o the_o crocus_n and_o regulus_n of_o antimony_n which_o be_v so_o indefinite_o small_a that_o no_o other_o membrane_n or_o organ_n of_o sensation_n but_o that_o at_o stomach_n can_v take_v notice_n thereof_o because_o the_o crocus_n and_o regulus_n after_o they_o have_v afford_v 1000_o vomit_n from_o their_o body_n be_v not_o sensible_o diminish_v either_o in_o weight_n or_o bulk_n nor_o do_v the_o stomach_n take_v and_o give_v a_o slight_a but_o very_o remarkable_a notice_n thereof_o that_o be_v sufficient_o powerful_a to_o excite_v not_o only_o all_o the_o natural_a power_n of_o the_o part_n and_o of_o all_o the_o auxiliary_a muscle_n that_o usual_o assist_v to_o vomit_v but_o to_o cause_v a_o contraction_n and_o that_o very_a often_o strong_o convulsive_a of_o all_o or_o most_o of_o the_o muscle_n and_o membrane_n of_o the_o whole_a body_n so_o great_a be_v the_o sway_n or_o regimen_n of_o the_o stomach_n by_o virtue_n of_o its_o exquisite_a sensility_n second_o by_o its_o give_a notice_n of_o inimicous_a particle_n and_o very_o tenuious_a effluvias_fw-la that_o fly_v in_o the_o air_n which_o no_o organ_n of_o sensation_n or_o membrane_n but_o that_o at_o stomach_n can_v observe_v for_o instance_n some_o that_o hate_v cat_n very_o much_o will_v know_v that_o there_o be_v a_o cat_n in_o the_o same_o room_n with_o they_o though_o silent_a and_o shut_v up_o in_o a_o trunk_n or_o cupboard_n where_o neither_o the_o eye_n ear_n nose_n taste_n or_o immediate_a feel_n can_v be_v at_o all_o concern_v or_o affect_v that_o it_o be_v the_o stomach_n that_o be_v affect_v be_v apparent_a though_o a_o thing_n not_o think_v of_o 1._o because_o the_o first_o notice_n they_o have_v be_v plain_o at_o stomach_n by_o a_o kind_n of_o faint_a distress_n not_o unlike_o a_o beginning_n nausea_n if_o the_o curious_a will_v inquire_v they_o will_v find_v it_o to_o be_v as_o i_o say_v 2._o because_o all_o perception_n of_o material_a thing_n be_v by_o sensation_n and_o that_o it_o be_v evident_a no_o other_o organ_n of_o sensation_n or_o membrane_n be_v concern_v 3._o because_o if_o the_o cat_n continue_v in_o the_o room_n and_o be_v not_o remove_v they_o fall_v a_o vomit_v or_o into_o anxiety_n or_o great_a distress_n at_o stomach_n or_o faint_n and_o syncopes_fw-la which_o be_v the_o common_a and_o know_v effect_n of_o a_o grieve_a or_o oppress_a stomach_n just_o so_o do_v it_o though_o these_o thing_n be_v not_o or_o not_o due_o observe_v take_v and_o give_v notice_n of_o pestilential_a effluvias_fw-la which_o cause_n the_o like_a faint_n or_o a_o kind_n of_o nausea_n at_o stomach_n thus_o people_n discern_v that_o they_o be_v as_o they_o call_v it_o plague_v strike_v and_o often_o fall_v as_o in_o the_o case_n of_o the_o effluvias_fw-la of_o the_o cat_n into_o dangerous_a deliquium_n and_o syncopes_fw-la of_o which_o many_o in_o plague_n time_n sudden_o die_v as_o cat_n hater_n will_v for_o aught_o i_o know_v if_o they_o continue_v long_o in_o the_o same_o room_n with_o a_o cat_n as_o they_o do_v with_o pestilential_a effluvias_fw-la therefore_o it_o be_v good_a present_o to_o remove_v they_o from_o the_o place_n wherein_o they_o be_v strike_v because_o the_o air_n as_o the_o room_n wherein_o the_o cat_n be_v be_v fill_v with_o the_o pernicious_a particle_n for_o you_o see_v in_o the_o case_n of_o the_o cat_n that_o remove_v the_o man_n or_o the_o cat_n give_v relief_n and_o it_o be_v better_a remove_v the_o man_n but_o that_o he_o be_v more_o cumbersome_a because_o the_o room_n be_v already_o taint_v with_o the_o effluvias_fw-la and_o in_o the_o case_n of_o the_o plague_n it_o be_v only_o the_o person_n that_o can_v
grievance_n cause_v contraction_n as_o have_v be_v manifest_o show_v 2._o because_o it_o cause_v a_o liberal_a perspiration_n which_o be_v a_o certain_a effect_n of_o relaxation_n as_o the_o want_n of_o it_o be_v of_o constriction_n and_o that_o it_o cause_v perspiration_n be_v most_o certain_a by_o statick_a experiment_n and_o demonstration_n sanctorius_n sect._n 7._o aph._n 19_o etc._n etc._n 3._o because_o the_o pleasure_n of_o wine_n and_o the_o venereal_a act_n manifest_o loosen_v all_o the_o limb_n as_o sleep_n do_v 4._o because_o that_o in_o those_o pleasure_n as_o also_o upon_o the_o sight_n of_o a_o belove_a mistress_n etc._n etc._n the_o eye_n look_v deadish_a by_o reason_n of_o the_o laxity_n of_o the_o cornea_n and_o that_o the_o pupilla_fw-la be_v dilate_v 5._o the_o skin_n as_o have_v be_v intimate_v look_v florid_n which_o make_v the_o ancient_n say_v that_o the_o blood_n and_o spirit_n come_v outward_a to_o meet_v the_o good_a and_o agreeable_a thing_n 6._o because_o all_o pleasure_n that_o be_v consistent_a with_o lie_v or_o sit_v still_o in_o a_o silent_a quiet_a manner_n incline_v we_o to_o sleep_v as_o music_n pleasant_a frication_n of_o the_o head_n back_o or_o any_o itch_a part_n sweet_a and_o acceptable_a o_o lour_v a_o thing_n of_o very_a acceptable_a taste_n hold_v in_o the_o mouth_n wine_n meat_n venus_n the_o pleasant_a sound_n of_o the_o fall_n of_o water_n whistle_v wind_n rock_v undulate_v in_o hammock_n etc._n etc._n 7._o because_o in_o coition_n it_o relax_n the_o neck_n of_o the_o womb_n to_o admit_v the_o animal_n elixir_n vitæ_fw-la of_o which_o we_o have_v most_o evident_a proof_n and_o some_o eminent_a instance_n that_o i_o forbear_v the_o relation_n of_o out_o of_o modesty_n 8._o pleasure_n cause_v a_o large_a and_o wide_a pulse_n as_o relaxation_n always_o do_v 9_o a_o loss_n or_o great_a diminution_n of_o sensation_n as_o in_o the_o venereal_a act._n which_o if_o it_o be_v of_o continuance_n will_v exact_o imitate_v opium_n in_o its_o effect_n upon_o drink_v wine_n etc._n etc._n the_o effect_n of_o which_o be_v of_o great_a duration_n and_o by_o take_v somewhat_o into_o the_o stomach_n as_o opium_n be_v be_v very_o like_o that_o of_o opium_n 10._o intense_a pleasure_n joy_n etc._n etc._n do_v frequent_o cause_v ecstasy_n syncopes_fw-la leipothymy_n which_o be_v only_o great_a relaxation_n as_o have_v be_v show_v 11._o you_o see_v that_o the_o pleasure_n of_o wine_n cause_v falter_v of_o the_o tongue_n which_o be_v the_o effect_n of_o relaxation_n as_o in_o sleep_n palsy_n etc._n etc._n and_o relax_n the_o whole_a body_n 12._o wine_n also_o prevent_v lassitude_n as_o all_o pleasant_a diversion_n do_v and_o cause_v all_o the_o effect_n of_o relaxation_n as_o take_v away_o pain_n cause_v a_o deadness_n of_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la floridity_n of_o the_o skin_n perspiration_n diminution_n of_o sensation_n mirth_n good_a humour_n sleep_v etc._n etc._n nâ—te_n that_o pleasure_n be_v general_o from_o external_n object_n and_o also_o short_a slight_a and_o transitory_a be_v the_o true_a reason_n of_o the_o great_a penury_n of_o thing_n that_o bear_v any_o complete_a analogy_n to_o opium_n in_o its_o great_a effect_n which_o make_v it_o seem_v more_o amaze_a and_o confound_v people_n whereas_o all_o the_o difference_n be_v nothing_o but_o its_o cause_v a_o internal_a intense_a and_o permanent_a pleasure_n all_o pleasure_n have_v the_o same_o effect_n but_o that_o they_o be_v short_a slight_a fade_a external_a inconsiderable_a intermit_a interrupt_v by_o some_o grievous_a object_n thought_n passion_n as_o fear_v care_n solicitude_n melancholy_a etc._n etc._n but_o the_o pleasure_n of_o opium_n we_o carry_v within_o we_o continual_o whether_o we_o will_v or_o no_o wake_v and_o sleep_v without_o any_o intermission_n or_o interruption_n and_o that_o in_o a_o high_a degree_n for_o many_o hour_n doubtless_o that_o of_o venus_n if_o iâ—_n be_v half_a as_o last_a will_v be_v as_o dangerous_a as_o that_o of_o a_o great_a do_v of_o opium_n or_o wine_n drink_v in_o a_o vast_a quantity_n which_o be_v in_o a_o manner_n as_o dangerous_a as_o opium_n and_o for_o the_o same_o reason_n viz._n by_o over-dosing_a a_o great_a relaxer_n by_o the_o pleasure_n it_o cause_n the_o cause_n why_o the_o pleasure_n of_o the_o venereal_a act_n as_o a_o large_a do_v of_o wine_n opium_n etc._n etc._n take_v away_o pain_n be_v 1._o because_o the_o sensitive_a soul_n can_v attend_v to_o two_o thing_n at_o once_o therefore_o when_o a_o sense_n of_o pleasure_n be_v introduce_v there_o can_v be_v at_o the_o same_o time_n a_o sense_n of_o pain_n which_o though_o not_o note_v in_o short_a transient_a and_o desultory_a pleasure_n as_o almost_o all_o be_v beside_o that_o of_o wine_n and_o opium_n yet_o the_o more_o permanent_a do_v exact_v our_o notice_n and_o attention_n because_o they_o exclude_v pain_n for_o so_o considerable_a a_o time_n that_o they_o amaze_v we_o 2._o because_o the_o sensitive_a soul_n attend_v more_o willing_o to_o pleasure_n than_o to_o pain_n so_o that_o pleasure_n engross_v his_o attention_n as_o be_v intimate_v 3._o because_o pleasure_n and_o pain_n or_o displeasure_n be_v contrary_n and_o can_v co-exist_a in_o the_o same_o subject_a or_o sensitive_a soul_n therefore_o when_o pleasure_n affect_v it_o pain_n can_v 4._o because_o relaxation_n which_o be_v the_o mechanical_a and_o main_a reason_n give_v such_o liberty_n to_o the_o animal_n spirit_n to_o expand_v that_o they_o become_v unfit_a for_o want_v of_o compressure_n to_o convey_v any_o impression_n smart_o which_o be_v requisite_a to_o cause_v a_o sense_n of_o pain_n that_o be_v cause_v by_o a_o smart_a impression_n to_o which_o you_o may_v add_v that_o 5._o pleasure_n and_o relaxation_n where_o they_o continue_v as_o in_o the_o case_n of_o wine_n and_o opium_n do_v high_o improve_v one_o another_o because_o they_o mutual_o cause_v one_o another_o for_o pleasure_n cause_v relaxation_n and_o relaxation_n as_o you_o sin_v in_o a_o sweet_a slumber_n etc._n etc._n pleasure_n so_o that_o permanent_a pleasure_n must_v high_o advance_v relaxation_n which_o take_v away_o pain_n by_o prevent_v all_o smartness_n of_o impression_n by_o the_o now_o yield_a nature_n of_o the_o expanded_a animal_n spirit_n which_o be_v as_o air_n in_o a_o gut_n half_n full_a or_o a_o rowl_n of_o card_a cotten_n or_o wool_n fit_a only_a to_o carry_v a_o gentle_a or_o no_o impression_n to_o the_o far_a end_n thereof_o so_o that_o upon_o the_o give_n of_o opium_n when_o the_o pâ—in_n do_v once_o begin_v to_o diminish_v it_o be_v not_o long_o afterward_o before_o it_o go_v quite_o off_o for_o if_o the_o pleasure_n do_v but_o take_v off_o one_o in_o ten_o of_o the_o pain_n it_o be_v a_o sign_n that_o it_o will_v be_v a_o easy_a matter_n for_o it_o that_o be_v upon_o the_o improvement_n for_o the_o reason_n aforesaid_a to_o overcome_v one_o in_o nine_o and_o yet_o much_o easy_a to_o overcome_v one_o in_o eight_o and_o so_o on_o therefore_o it_o be_v a_o certain_a sign_n that_o you_o have_v give_v enough_o to_o take_v away_o the_o pain_n if_o it_o once_o sensible_o decrease_v and_o consequent_o all_o physician_n shall_v then_o not_o give_v any_o more_o opium_n though_o the_o pain_n be_v not_o yet_o quite_o off_o for_o if_o the_o relaxation_n cause_v by_o pleasant_a sensation_n be_v of_o force_n enough_o to_o overcome_v the_o great_a contraction_n by_o the_o great_a pain_n which_o oppose_v it_o more_o strong_o it_o will_v suffice_v to_o overcome_v the_o less_o this_o intimate_v and_o it_o be_v experience_v that_o dose_n must_v be_v proportion_v to_o the_o pain_n for_o though_o a_o few_o glass_n of_o wine_n may_v take_v off_o the_o sense_n of_o a_o small_a pain_n more_o must_v be_v drink_v to_o take_v off_o a_o great_a and_o so_o of_o opium_n because_o the_o contraction_n by_o pain_n resist_v the_o relaxation_n by_o pleasure_n have_v show_v how_o sleep_n and_o pleasure_n take_v away_o pain_n by_o relaxation_n permit_v the_o animal_n spirit_n to_o expand_v and_o grow_v unfit_a to_o carry_v impression_n smart_o and_o that_o therefore_o sleep_v stop_n or_o moderate_v all_o flux_n that_o depend_v upon_o irritation_n of_o the_o sensile_a part_n to_o cause_v they_o to_o contract_n and_o squeeze_v out_o the_o humour_n that_o cause_v the_o flux_n while_o the_o same_o relaxation_n open_v the_o pore_n and_o so_o let_v out_o the_o fume_n of_o the_o body_n which_o only_o like_o smoke_n in_o a_o chimney_n require_v a_o open_a passage_n by_o reason_n of_o their_o levity_n which_o carry_v they_o off_o it_o plain_o appear_v how_o pleasure_n that_o take_v away_o the_o sense_n of_o pain_n or_o irritation_n by_o the_o like_a relaxation_n must_v stop_v the_o first_o sort_n of_o flux_n that_o require_v the_o irritation_n to_o contract_v the_o part_n and_o promote_v that_o of_o perspiration_n as_o in_o sleep_n which_o require_v
and_o frequent_a erection_n be_v and_o must_v be_v from_o the_o same_o cause_n 17._o nocturnal_a pollution_n be_v necessary_a consequence_n of_o the_o relaxation_n and_o the_o titillation_n cause_v by_o those_o volatile_a salt_n as_o be_v say_v chap._n xxiii_o the_o explication_n of_o the_o effect_n of_o leave_v off_o opium_n after_o a_o long_a and_o lavish_a use_v thereof_o i._o great_a and_o even_o intolerable_a distress_n anxiety_n and_o depression_n of_o spirit_n do_v happen_v 1._o because_o the_o sensitive_a soul_n who_o be_v so_o much_o comfort_v divert_v and_o support_v by_o the_o habitual_a and_o dear_o belove_a pleasure_n that_o opium_n cause_n be_v sudden_o deprive_v thereof_o by_o which_o it_o be_v main_o sustain_v be_v exceed_o disappoint_v and_o cast_v down_o 2._o because_o he_o now_o labour_v under_o the_o sore_a burden_n of_o the_o three_o contraction_n so_o that_o every_o thing_n seem_v and_o be_v real_o more_o grievous_a â—o_o he_o for_o now_o it_o act_v as_o one_o in_o pain_n or_o grief_n and_o every_o thing_n affect_v he_o more_o smart_o proportionable_a to_o the_o compression_n cause_v thereby_o of_o the_o animal_n spirit_n unless_o he_o return_v to_o the_o pleasure_n of_o opium_n which_o elevate_v it_o again_o or_o use_v generous_a wine_n as_o its_o substitute_n though_o it_o do_v not_o equal_v it_o either_o in_o the_o intenseness_n or_o duration_n of_o the_o pleasure_n unless_o repeat_v as_o i_o have_v some_o where_o direct_v once_o in_o half_a a_o hour_n or_o a_o hour_n in_o a_o moderate_a manner_n which_o cause_v a_o continuance_n of_o the_o pleasure_n though_o it_o can_v equal_v the_o intenseness_n of_o that_o of_o opium_n which_o therefore_o have_v the_o great_a effect_n ii_o a_o return_n of_o all_o disease_n pain_n and_o disaster_n must_v happen_v general_o because_o the_o opium_n take_v they_o off_o by_o a_o bare_a diversion_n of_o the_o sense_n thereof_o by_o pleasure_n iii_o dangerous_a looseness_n happen_v sometime_o because_o the_o sensation_n grow_v more_o grievous_a for_o as_o the_o pleasant_a sensation_n cause_v by_o opium_n take_v away_o the_o perception_n of_o the_o irritation_n of_o humour_n so_o the_o grievance_n of_o lose_v that_o pleasure_n cause_v contraction_n make_v all_o sensation_n smart_a and_o consequent_o more_o irritate_v so_o that_o the_o humour_n have_v thereby_o more_o of_o the_o effect_n of_o purger_n which_o operate_v as_o all_o agree_v by_o irritation_n beside_o that_o the_o humour_n before_o detain_v and_o suspend_v by_o relaxation_n as_o in_o sleep_n be_v now_o therefore_o pour_v down_o in_o great_a quantity_n by_o the_o advance_a contraction_n squeese_v they_o out_o as_o the_o return_n of_o the_o vigilative_a contraction_n after_o sleep_n cause_n man_n to_o be_v more_o apt_a to_o go_v to_o stool_n upon_o awake_v or_o get_v up_o in_o the_o morning_n which_o may_v be_v well_o compare_v in_o some_o measure_n to_o purge_v after_o leave_v off_o the_o use_n of_o opium_n since_o it_o relax_n as_o sleep_n do_v and_o that_o for_o a_o much_o long_a time_n by_o a_o continue_a use_n thereof_o iv_o death_n common_o follow_v for_o all_o the_o reason_n aforesaid_a especial_o the_o great_a and_o intolerable_a distress_n of_o soul_n that_o they_o be_v under_o unless_o opium_n be_v use_v which_o soon_o set_v they_o right_o or_o wine_n its_o substitute_n so_o frequent_o use_v as_o to_o continue_v its_o cordial_a pleasure_n at_o stomach_n nothing_o now_o remain_v but_o to_o take_v a_o short_a review_n to_o see_v whether_o i_o have_v explain_v all_o the_o amaze_a contradiction_n that_o seem_v to_o be_v in_o the_o effect_n of_o opium_n for_o though_o it_o be_v real_o do_v yet_o may_v it_o not_o so_o well_o appear_v as_o when_o set_v one_o against_o the_o other_o it_o will_v be_v tautology_n to_o repeat_v all_o the_o reason_n therefore_o i_o shall_v only_o mention_v they_o in_o the_o close_a order_n i_o at_o first_o enumerate_v they_o that_o you_o may_v see_v that_o they_o be_v all_o explicate_v in_o the_o former_a discourse_n you_o may_v well_o remember_v that_o i_o have_v show_v 1._o how_o it_o cause_v sleep_v and_o watch_v in_o divers_a person_n 2._o how_o it_o cause_v and_o prevent_v sweat_n 3._o how_o it_o relax_n and_o stop_n looseness_n even_o by_o relax_v 4._o how_o it_o stop_v flux_n and_o promote_v sweat_v and_o perspiration_n 5._o how_o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v it_o 6._o how_o it_o cause_v stupidity_n if_o you_o sit_v or_o lie_v still_o otherwise_o promptitude_n in_o business_n 7._o how_o it_o cause_v cloudiness_n and_o serenity_n that_o if_o one_o lie_v still_o and_o doze_n this_o if_o he_o keep_v in_o action_n that_o by_o a_o excessive_a and_o lavish_a use_v thereof_o which_o cause_v moapishness_n this_o by_o a_o temperate_a occasional_a take_v thereof_o especial_o in_o the_o morning_n upon_o journey_n etc._n etc._n 8._o how_o it_o excite_v the_o spirit_n yet_o quiet_v and_o compose_v they_o in_o hysterick_n fit_v diary_n fever_n from_o pain_n commotion_n etc._n etc._n 9_o how_o that_o it_o be_v very_o hot_a and_o take_v of_o fever_n 10._o how_o though_o it_o be_v hot_a and_o bitter_a yet_o it_o lessen_v appetite_n and_o hunger_n which_o be_v a_o grievous_a sensation_n by_o cause_v a_o pleasant_a one_o 11._o how_o it_o sometime_o stop_v urine_n by_o relax_v the_o bladder_n suspending_a humour_n etc._n etc._n and_o promote_v it_o by_o its_o tickle_a volatile_a salt_n as_o cantharides_n bee_n aunt_n etc._n etc._n do_v 12._o how_o it_o relax_n and_o thereby_o weaken_v as_o in_o sleep_n etc._n etc._n yet_o enable_v to_o perform_v labour_n journey_n etc._n etc._n with_o great_a euphory_n by_o divertive_a pleasure_n 13._o how_o it_o cause_v and_o prevent_v abortion_n that_o by_o over-relaxing_a this_o by_o allay_a pain_n terror_n etc._n etc._n that_o may_v cause_v it_o 14._o how_o it_o stop_v vomit_v by_o take_v off_o irritation_n etc._n etc._n and_o cause_v it_o by_o the_o adherence_n of_o its_o indigestible_a and_o viscid_a rosin_n 15._o how_o it_o stop_v purge_v and_o sometime_o cause_v it_o by_o the_o dissolution_n of_o its_o rosin_n by_o a_o strong_a digestion_n fix_a salt_n etc._n etc._n when_o its_o quantity_n be_v considerable_a which_o make_v it_o happen_v but_o rare_o 16._o how_o though_o acrimonious_a it_o take_v away_o the_o sense_n of_o acrimony_n 17._o how_o it_o cause_v madness_n and_o cure_v it_o by_o compose_v the_o spirit_n etc._n etc._n 18._o how_o it_o cause_v palsy_n by_o relax_v the_o part_n and_o make_v they_o susceptible_a of_o humour_n cause_v ill_a digestion_n etc._n etc._n and_o may_v cure_v they_o as_o dr._n willis_n give_v a_o instance_n by_o open_v the_o pore_n 19_o how_o it_o cause_v palsy_n and_o cure_n stupor_n etc._n etc._n that_o proceed_v from_o cold_a and_o contract_n cause_n 20._o how_o it_o cause_v dryness_n in_o the_o mouth_n yet_o by_o take_v off_o fever_n often_o cure_v it_o 21._o how_o it_o take_v off_o hiccough_n and_o cause_v they_o as_o it_o do_v vomit_v and_o for_o the_o same_o cause_n 22._o how_o it_o stanch_v blood_n by_o quiet_v its_o motion_n yet_o promote_v the_o menses_fw-la and_o lochia_n by_o relax_v open_v and_o widen_v the_o vessel_n and_o pore_n 23._o how_o it_o stop_v critical_a motion_n that_o depend_v upon_o irritation_n and_o contraction_n and_o promote_v such_o as_o depend_v upon_o open_v the_o pore_n 24._o how_o it_o revive_v people_n that_o be_v at_o the_o point_n of_o death_n for_o want_n of_o opium_n or_o by_o violent_a contraction_n and_o convulsion_n and_o be_v fatal_a to_o other_o weak_a person_n 25._o how_o it_o cause_v convulsion_n by_o its_o grieve_v rosin_n and_o cure_v they_o by_o quiet_v and_o compose_v the_o spirit_n by_o please_v they_o 26._o how_o it_o cause_v contraction_n by_o the_o grievous_a sensation_n that_o its_o rosin_n cause_n and_o relaxation_n by_o the_o pleasant_a sensation_n that_o its_o salvolatile_a oleosum_fw-la cause_n by_o that_o it_o cause_v many_o ill_a effect_n not_o here_o name_v and_o by_o this_o it_o cure_v they_o for_o how_o can_v such_o contrary_a cause_n according_a as_o one_o or_o the_o other_o prevail_v not_o cause_v contrary_a and_o seem_o contradictory_n effect_n at_o divers_a time_n and_o in_o divers_a person_n 27._o how_o it_o relax_n yet_o cause_v the_o tension_n rigidity_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n by_o its_o titillation_n thus_o have_v you_o all_o even_o the_o most_o mysterious_a and_o seem_o contradictory_n effect_n of_o opium_n explain_v and_o reconcile_v and_o that_o so_o easy_o that_o if_o there_o be_v no_o other_o proof_n of_o the_o truth_n of_o my_o foundation_n it_o be_v sufficient_a to_o convince_v any_o man_n of_o its_o validity_n consider_v the_o vastness_n of_o the_o number_n and_o perplexity_n of_o the_o nature_n of_o those_o effect_n that_o be_v all_o with_o such_o facility_n explain_v be_v able_a even_o
darkness_n of_o the_o eye_n see_v thing_n double_a various_a colour_n before_o the_o eye_n loss_n of_o feel_v ease_n from_o pain_n etc._n etc._n deadness_n of_o the_o eye_n to_o the_o view_n dilatation_n of_o the_o pupilla_fw-la efflorescence_n of_o the_o skin_n laxity_n of_o the_o low_a jaw_n intumescence_n and_o laxity_n of_o the_o lip_n falter_v of_o the_o tongue_n sardonick_a laughter_n laxity_n and_o weakness_n of_o all_o part_n a_o general_a ineptitude_n to_o motion_n failure_n in_o make_v water_n go_v to_o stool_n and_o in_o all_o thing_n that_o require_v strength_n contraction_n motion_n etc._n etc._n difficulty_n of_o breathe_v a_o wide_a and_o slow_a pulse_n a_o condition_n in_o general_a very_a like_o that_o of_o drunkenness_n which_o also_o proceed_v from_o relaxation_n second_o when_o you_o be_v satisfy_v that_o relaxation_n be_v the_o cause_n use_v all_o mean_n to_o procure_v a_o due_a contraction_n of_o all_o part_n which_o be_v to_o be_v do_v 1._o by_o remove_v the_o cause_n of_o the_o relaxation_n 2._o by_o use_v all_o good_a mean_n for_o contraction_n first_o therefore_o give_v a_o brisk_a quick_a and_o strong_a vomit_n both_o to_o discharge_v the_o opiate_n and_o cause_n contraction_n of_o part_n by_o a_o grievous_a sensation_n proportion_n it_o to_o the_o deadness_n stupidity_n or_o sleepiness_n of_o the_o person_n so_o as_o to_o give_v it_o of_o twice_o the_o ordinary_a strength_n of_o vomit_n in_o case_n there_o be_v great_a danger_n from_o those_o symptom_n and_o that_o they_o be_v of_o a_o high_a nature_n after_o the_o person_n have_v vomit_v 3_o or_o 4_o time_n or_o so_o often_o as_o that_o you_o may_v judge_v the_o stomach_n well_o clear_v of_o the_o opiate_n give_v half_o a_o ounce_n of_o cream_n of_o tartar_n fine_o powder_v in_o thin_a broth_n whey_n water_n small_a beer_n or_o any_o convenient_a liquid_a which_o will_v correct_v the_o opiate_n if_o any_o remain_v at_o stomach_n turn_v the_o vomit_n to_o a_o purger_n to_o clear_v the_o intestine_n also_o and_o contribute_v much_o to_o the_o contraction_n of_o part_n which_o you_o must_v always_o have_v in_o your_o thought_n as_o the_o roll_a intention_n in_o this_o case_n therefore_o second_o you_o must_v use_v contracter_n all_o the_o time_n the_o chief_a of_o which_o be_v cold_a grievous_a sensation_n or_o pain_n terror_n fear_v voluntary_a motion_n and_o acid_n which_o last_n can_v be_v so_o well_o use_v during_o the_o vomit_v lest_o they_o stop_v it_o therefore_o especial_o if_o the_o person_n be_v very_o stupid_a keep_v he_o very_o cold_a for_o he_o will_v hardly_o feel_v it_o nor_o take_v cold_a because_o the_o relaxation_n and_o the_o insensibleness_n of_o grievance_n by_o cold_a etc._n etc._n keep_v the_o pore_n open_a let_v he_o be_v if_o possible_a in_o some_o motion_n as_o walk_v hew_v saw_v knock_v tug_v etc._n etc._n the_o more_o violent_a it_o be_v the_o better_a because_o it_o cause_v more_o contraction_n and_o agitation_n to_o prevent_v sopor_n to_o force_v he_o to_o motion_n if_o need_v be_v prick_a pinch_a or_o whip_v he_o about_o the_o leg_n etc._n etc._n will_v be_v of_o good_a use_n because_o grievous_a sensation_n add_v defensive_a contraction_n which_o be_v the_o great_a sort_n to_o that_o of_o the_o intentive_a contraction_n by_o voluntary_a motion_n these_o mean_n fail_v he_o shall_v be_v expose_v stark_o naked_a to_o the_o cold_a air_n and_o in_o desperate_a case_n throw_v sudden_o at_o unaware_o into_o cold_a water_n by_o which_o mean_v you_o cause_n terror_n surprise_v and_o cold_a which_o be_v the_o high_a and_o most_o forcible_a contracter_n to_o conspire_v to_o the_o contraction_n of_o part_n hence_o it_o be_v that_o drunken_a people_n who_o be_v so_o from_o relaxation_n become_v sober_a as_o in_o a_o moment_n by_o that_o mean_n all_o the_o time_n but_o during_o the_o vomit_v let_v he_o use_v cold_a acid_n in_o great_a plenty_n and_o very_o manifest_o acid_a for_o they_o will_v not_o only_o contribute_v to_o contraction_n but_o very_o much_o correct_v the_o opiate_n to_o this_o end_n juice_n of_o orange_n or_o lemon_n verjuice_n or_o water_n acidulate_v to_o a_o good_a degree_n by_o verjuice_n vinegar_n juice_n of_o lemon_n spirit_n of_o vitriol_n sulphur_n or_o the_o like_a will_v be_v very_o proper_a where_o you_o have_v not_o the_o convenience_n to_o plunge_v they_o into_o cold_a water_n as_o be_v direct_v dash_v or_o pump_v very_o cold_a water_n or_o water_n with_o a_o four_o part_n of_o vinegar_n upon_o their_o naked_a body_n will_v be_v of_o great_a use_n especial_o if_o surprise_o do_v to_o cause_v the_o more_o terror_n and_o concern_v these_o thing_n may_v be_v do_v more_o or_o lâ—ss_o as_o cause_n may_v require_v which_o must_v be_v leave_v to_o the_o discretion_n of_o the_o present_a physician_n or_o friend_n and_o standard_n by_o in_o case_n there_o be_v no_o physician_n i_o only_o caution_n that_o contracter_n shall_v not_o be_v use_v too_o spare_o and_o that_o you_o shall_v never_o cease_v to_o advance_v in_o the_o use_n of_o they_o till_o you_o perceive_v their_o good_a effect_n and_o then_o to_o continue_v they_o as_o occasion_n require_v note_v that_o the_o case_n may_v well_o happen_v that_o the_o rosin_n may_v stick_v at_o stomach_n and_o yet_o no_o sign_n or_o symptom_n appear_v but_o those_o of_o relaxation_n by_o reason_n that_o the_o feel_n at_o stomach_n may_v thereby_o be_v disable_v to_o take_v any_o notice_n of_o it_o to_o be_v sure_a of_o this_o you_o have_v no_o other_o mean_n because_o the_o symptom_n and_o effect_n of_o grievous_a sensation_n can_v appear_v where_o it_o be_v not_o for_o the_o aforesaid_a reason_n but_o to_o examine_v whether_o the_o opiate_n be_v a_o resinous_a one_o as_o crude_a opium_n extract_v out_o of_o spirit_n of_o wine_n or_o the_o like_a for_o than_o you_o may_v conclude_v especial_o if_o they_o be_v give_v in_o a_o massy_a solid_a form_n as_o that_o of_o pill_n etc._n etc._n without_o sever_n the_o particle_n of_o the_o rosin_n by_o other_o thing_n as_o the_o yolk_n of_o a_o egg_n etc._n etc._n that_o the_o rosin_n may_v in_o all_o probability_n stick_v at_o stomach_n though_o its_o symptom_n do_v not_o appear_v for_o the_o aforesaid_a reason_n in_o such_o a_o case_n the_o best_a advice_n that_o i_o can_v give_v be_v external_o to_o use_v all_o contract_n mean_v as_o be_v direct_v and_o internal_o the_o mean_v prescribe_v for_o dissolution_n of_o the_o rosin_n for_o you_o will_v thereby_o answer_v both_o intention_n failure_n of_o make_v water_n often_o happen_v in_o these_o case_n which_o you_o may_v general_o help_v by_o only_o clap_v the_o scrotum_fw-la to_o the_o cold_a chamber_n pot_n or_o into_o cold_a water_n and_o if_o that_o will_v not_o do_v put_v some_o vinegar_n into_o the_o water_n and_o that_o fail_v he_o must_v be_v strip_v and_o cold_a water_n pump_v or_o dash_v upon_o the_o region_n of_o the_o bladder_n iii_o to_o cure_v the_o ill_a effect_n of_o a_o long_a and_o lavish_a use_n of_o opium_n these_o effect_n as_o you_o may_v easy_o observe_v if_o you_o take_v a_o view_n of_o they_o where_o they_o be_v enumerate_v in_o chap._n 6._o be_v either_o 1._o from_o a_o overmuch_o and_o habitual_a relaxation_n of_o part_n as_o weakness_n a_o moapish_a disposition_n diminution_n of_o appetite_n weakness_n of_o digestion_n dropsy_n weakness_n of_o memory_n etc._n etc._n or_o 2._o from_o acrimony_n as_o frequent_a irritation_n to_o make_v water_n priapism_n erection_n of_o the_o penis_n fruitless_a inclination_n to_o venery_n etc._n etc._n in_o this_o case_n as_o in_o that_o of_o old_a drunkard_n which_o be_v much_o the_o same_o there_o be_v no_o good_a to_o be_v do_v till_o the_o habitual_a cause_n be_v remove_v viz._n the_o take_v of_o opium_n which_o sudden_o to_o leave_v off_o be_v as_o be_v show_v very_o dangerous_a therefore_o in_o order_n to_o leave_v it_o off_o safe_o 1._o you_o must_v stop_v your_o hand_n and_o not_o increase_v the_o do_v that_o be_v take_v by_o which_o mean_v it_o will_v come_v gradual_o to_o have_v little_a or_o no_o effect_n 2._o when_o you_o find_v that_o it_o be_v come_v to_o that_o pass_n your_o work_n be_v half_o do_v then_o only_o lessen_v it_o 100th_o part_n every_o day_n till_o you_o come_v to_o take_v none_o at_o all_o 3._o if_o during_o this_o retrograde_a course_n you_o find_v any_o faintness_n drink_v a_o glass_n of_o good_a stomach-wine_n toties_fw-la quoties_fw-la as_o gentian_n or_o centary_a wine_n or_o the_o like_a make_v by_o infusion_n in_o claret_n or_o if_o you_o want_v such_o a_o glass_n of_o the_o claret_n itself_o which_o thing_n will_v excite_v the_o spirit_n and_o help_v digestion_n 4._o when_o you_o have_v quite_o end_v the_o take_v of_o opium_n continue_v to_o use_v such_o wine_n when_o you_o be_v faint_a and_o every_o morning_n take_v in_o a_o glass_n of_o
spirit_n and_o not_o a_o over-relaxation_n or_o dilatation_n of_o the_o pore_n which_o must_v be_v well_o distinguish_v i._o the_o form_n must_v be_v liquid_a in_o all_o fever_n and_o be_v also_o most_o convenient_a general_o speak_v ii_o the_o do_v may_v be_v the_o moderate_a or_o middling_a except_o it_o be_v where_o the_o pain_n be_v great_a or_o where_o much_o of_o the_o opiate_n be_v lose_v as_o in_o vomit_v looseness_n etc._n etc._n for_o which_o see_v the_o general_n rule_v iii_o the_o vehicle_n shall_v be_v general_o speak_v cool_v compose_v and_o incrassate_v liquid_n as_o emulsion_n milk_n and_o water_n or_o the_o like_a but_o in_o settle_v the_o stomach_n use_v agreeable_a warm_a and_o comfortable_a cordial_n or_o wine_n burn_v with_o aromatics_n or_o the_o like_a iv_o the_o time_n be_v when_o it_o be_v convenient_a according_a to_o the_o general_n rule_v and_o your_o intention_n of_o its_o operation_n therefore_o where_o there_o be_v periodical_a paroxysm_n or_o exacerbation_n as_o in_o the_o smallpox_n and_o many_o disease_n in_o the_o afternoon_n or_o towards_o the_o evening_n give_v it_o the_o due_a time_n before_o that_o it_o may_v have_v its_o full_a effect_n by_o the_o time_n the_o paroxysm_n or_o exacerbation_n be_v expect_v to_o begin_v and_o be_v not_o so_o mad_a as_o to_o be_v regulate_v by_o night_n or_o day_n or_o bedtime_n etc._n etc._n as_o be_v usual_a which_o be_v no_o symptom_n sign_n or_o effect_n of_o the_o distemper_n but_o of_o the_o motion_n or_o position_n of_o the_o sun_n star_n &c_n &c_n which_o be_v not_o the_o subject_n of_o your_o cure_n nor_o can_v be_v the_o want_n of_o which_o most_o obvious_a and_o rational_a practice_n have_v sad_o disappoint_v inconsiderate_a physician_n and_o often_o hazard_v if_o not_o destroy_v the_o patient_n v._o the_o regimen_n be_v the_o same_o as_o that_o to_o cause_v sleep_n which_o you_o have_v in_o chap._n 35._o and_o shall_v be_v by_o all_o mean_v use_v in_o this_o case_n 1._o note_v that_o opiate_n be_v not_o to_o be_v use_v as_o have_v be_v intimate_v where_o the_o commotion_n flux_n etc._n etc._n be_v for_o apparent_a and_o speedy_a benefit_n of_o nature_n as_o in_o vomit_v upon_o repletion_n or_o to_o discharge_v the_o stomach_n of_o somewhat_o that_o offend_v it_o or_o a_o looseness_n to_o clear_v the_o intestine_n or_o the_o like_a 2._o note_v that_o when_o any_o evacuation_n be_v to_o be_v make_v by_o vomit_n or_o stool_n the_o best_a way_n in_o these_o case_n be_v to_o use_v large_a dilution_n of_o some_o contemperate_a liquid_a instead_o of_o vomitory_n and_o purger_n therefore_o use_v only_o lukewarm_a water_n or_o which_o be_v best_a boil_v with_o a_o little_a carduus_fw-la in_o it_o or_o carduus-posset_n or_o the_o like_a to_o cause_v vomit_v and_o more_o agreeable_a dilution_n for_o the_o intestine_n to_o wash_v off_o ill_a humour_n as_o a_o gallon_n of_o water_n with_o half_a a_o ounce_n of_o cream_n of_o tartar_n or_o rather_o the_o purge_a salt_n of_o the_o water_n dissolve_v in_o it_o or_o some_o part_n thereof_o use_v all_o cold_a or_o but_o very_o little_o warm_v give_v the_o opiate_n or_o panacea_fw-la immediate_o after_o the_o person_n have_v do_v vomit_v or_o purge_v in_o a_o small_a glass_n of_o wine_n or_o agreeable_a cordial_n to_o warm_v and_o comfort_v the_o stomach_n and_o intestine_n which_o because_o of_o the_o smallness_n of_o the_o quantity_n the_o moisture_n and_o coolness_n of_o the_o dilute_a liquid_n and_o the_o opiate_n can_v cause_v no_o inconvenience_n by_o its_o inconsiderable_a heat_n chap._n xxxiii_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o relax_v have_v show_v that_o opiate_n relax_v all_o the_o sensile_a part_n of_o the_o body_n and_o bow_n and_o why_o it_o follow_v that_o they_o be_v of_o excellent_a use_n 1._o to_o prevent_v and_o take_v away_o all_o contraction_n that_o happen_v from_o grievous_a passion_n or_o sensation_n or_o pain_n as_o convulsion_n sâ—iverings_n shake_v cramp_n tension_n palpitation_n and_o tremor_n of_o the_o heart_n from_o fear_n terror_n grief_n melancholy_n anxiety_n solicitude_n anger_n fretfulness_n concern_v surprise_v etc._n etc._n or_o from_o cold_a pain_n acid_n etc._n etc._n as_o contraction_n of_o the_o sphincter_n of_o the_o bladder_n from_o those_o cause_n by_o which_o the_o urine_n be_v often_o stop_v as_o also_o by_o the_o pain_n from_o the_o haemorrhoid_v inflammation_n small_a pox_n colick_n acrimony_n excoriation_n etc._n etc._n which_o often_o hinder_v the_o make_n of_o water_n as_o they_o also_o do_v sometime_o go_v to_o stool_n swallow_v etc._n etc._n shiver_a in_o ague-fits_a stupor_n from_o cold_a or_o pain_v which_o as_o be_v show_v proceed_v from_o a_o violent_a contraction_n in_o all_o which_o it_o will_v scarce_o ever_o fail_v of_o due_a effect_n by_o this_o mean_v you_o may_v as_o i_o have_v often_o do_v cure_v those_o disaster_n safe_o speedy_o and_o pleasant_o even_o to_o a_o wonder_n and_o amazement_n as_o if_o charm_v by_o a_o spell_n when_o other_o know_v not_o what_o hand_n to_o put_v to_o they_o and_o be_v quite_o baffle_v thereby_o by_o the_o same_o mean_n though_o little_a or_o not_o at_o all_o mind_a you_o may_v prevent_v great_a tumor_n upon_o pain_n as_o when_o by_o a_o thorn_n or_o any_o grievous_a pain_n the_o arm_n leg_n thigh_n etc._n etc._n begin_v to_o swell_v for_o the_o swell_a which_o often_o grow_v prodigious_o and_o seize_v the_o whole_a limb_n if_o not_o a_o great_a part_n of_o the_o body_n threaten_v and_o often_o cause_v mortification_n and_o death_n itself_o be_v cause_v by_o the_o pain_n contract_v and_o so_o gird_v the_o part_n that_o the_o blood_n lympha_fw-la &c._n &c._n can_v pass_v by_o which_o mean_v the_o humour_n be_v stagnate_v and_o crowd_v in_o by_o the_o force_n of_o the_o artery_n and_o damn_v up_o by_o the_o contraction_n most_o dreadful_a tumor_n happen_v whereas_o the_o pain_n be_v take_v away_o by_o the_o opiate_n and_o all_o the_o part_n relax_v they_o be_v and_o must_v be_v prevent_v by_o plain_a mechanism_n if_o use_v timely_a for_o pain_n can_v cause_v tumor_n by_o no_o other_o mean_n beside_o contraction_n which_o opium_n must_v prevent_v by_o take_v away_o the_o very_a pain_n itself_o 2._o to_o help_v the_o cure_n of_o all_o other_o contraction_n as_o tension_n rigidity_n of_o nerve_n membrane_n tendon_n ligament_n muscle_n etc._n etc._n 3._o to_o relax_v or_o make_v way_n for_o thing_n to_o pass_v as_o sweat_v 〈◊〉_d small_a pox_n measles_n pestilential_a or_o venomous_a esslâ—vias_n mâ—nses_n lochia_n and_o the_o like_a to_o pass_v through_o the_o skin_n or_o pore_n a_o child_n dead_z or_o alive_a afterbirth_n mole_n clod_v blood_n etc._n etc._n to_o pass_v through_o the_o neck_n of_o the_o womb_n when_o too_o narrow_a by_o nature_n or_o contract_v by_o pain_n cold_a terror_n etc._n etc._n a_o stone_n to_o pass_v the_o ureter_n or_o neck_n of_o the_o bladder_n by_o take_v away_o the_o pain_n that_o contract_v they_o and_o hinder_v the_o passage_n of_o the_o stone_n so_o that_o in_o the_o hand_n of_o a_o ingenious_a physician_n there_o be_v not_o a_o better_a nor_o as_o good_a a_o remedy_n to_o cause_v a_o stone_n of_o any_o passable_a bigness_n to_o come_v away_o for_o it_o pass_v through_o the_o relaxed_a or_o widen_v passage_n without_o pain_n to_o help_v which_o other_o relaxer_n as_o warmth_n 〈◊〉_d bathâ—_n fomentation_n clyster_n together_o with_o slippery_a and_o emollient_a thing_n inward_o take_v and_o at_o last_o a_o great_a stream_n of_o urine_n well_o contrive_v and_o time_v when_o the_o part_n be_v most_o relax_v supple_v and_o lubricate_v do_v much_o conduce_v i_o will_v have_v all_o who_o be_v trouble_v with_o the_o stone_n note_v this_o note_v also_o that_o to_o hold_v and_o dam_v up_o the_o urine_n a_o long_a time_n be_v of_o excellent_a use_n well_o manage_v when_o the_o stone_n be_v in_o the_o ureter_n because_o when_o the_o urine_n have_v fill_v up_o the_o bladder_n very_o tight_o that_o it_o will_v receive_v no_o more_o it_o must_v distend_v the_o ureter_n which_o be_v the_o cause_n that_o very_o many_o be_v ease_v either_o by_o the_o removal_n or_o discharge_v of_o the_o stone_n after_o a_o set_a time_n which_o give_v occasion_n to_o call_v they_o fit_v of_o the_o stone_n because_o they_o last_o for_o much_o about_o the_o same_o length_n of_o time_n however_o the_o large_a and_o sudden_a evacuation_n of_o urine_n must_v by_o leave_v the_o part_n loose_a etc._n etc._n conduce_v very_o much_o to_o the_o passage_n of_o the_o stone_n clod_n of_o blood_n phlegm_n matter_n etc._n etc._n that_o step_v the_o urine_n 4._o to_o relax_v or_o make_v way_n for_o thing_n to_o be_v put_v into_o the_o body_n when_o there_o be_v occasion_n as_o in_o reduction_n of_o hernias_fw-la or_o rupture_n of_o a_o fall_v fundament_n womb_n or_o
the_o pore_n therefore_o 1._o it_o be_v of_o excellent_a use_n to_o carry_v away_o noxious_a vapour_n or_o effluvia_n by_o the_o pore_n of_o the_o skin_n to_o prevent_v putrefaction_n and_o cure_v they_o to_o carry_v off_o venomous_a particle_n in_o the_o plague_n infectious_a distemper_n bite_n of_o serpent_n mad_a dog_n etc._n etc._n ill_a fume_n wind_n in_o the_o blood_n or_o habit_n of_o the_o body_n that_o cause_v stitch_n tumour_n etc._n etc._n 2._o to_o carry_v off_o noxious_a humour_n the_o same_o way_n especial_o such_o as_o stagnate_n or_o offend_v in_o the_o habit_n of_o the_o body_n as_o in_o cold_n intercutaneous_a water_n leâ—cophlegmatia_n and_o sometime_o in_o dropsy_n as_o dr._n willis_n observe_v in_o declination_n of_o disease_n to_o carry_v off_o the_o concoct_v morbid_v matter_n in_o rheumatism_n and_o gout_n particular_o that_o which_o be_v call_v the_o wind_n gout_n 3._o when_o perspiration_n be_v any_o way_n hinder_v as_o by_o grievous_a passion_n sensation_n or_o pain_n acid_a austere_a or_o cold_a humour_n by_o which_o many_o disease_n be_v cause_v thus_o it_o be_v very_o useful_a in_o grief_n sorrow_n anxiety_n solicitude_n melancholy_a panic_n fear_n gachexy_n scurvy_n hypochondriacal_a case_n wherein_o it_o perform_v wonderful_o when_o all_o thing_n fail_v as_o you_o find_v in_o chap._n 24._o 4._o to_o promote_v the_o menses_fw-la or_o lochia_n when_o stop_v by_o reason_n of_o the_o constriction_n of_o the_o pore_n by_o such_o grievous_a passion_n or_o sensation_n or_o by_o acid_n austere_a or_o cold_a humour_n external_a cold_a etc._n etc._n by_o its_o relax_a and_o open_v the_o pore_n and_o way_n and_o solicit_v the_o part_n by_o a_o gentle_a agreeable_a titillation_n hence_o some_o just_o call_v it_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o be_v a_o opener_n of_o the_o mouth_n of_o the_o vein_n or_o bloud-vessel_n by_o which_o mean_v as_o have_v be_v show_v puberty_n coition_n etc._n etc._n do_v kind_o and_o natural_o cause_v the_o menses_fw-la to_o flow_v while_o the_o same_o relaxation_n cause_v a_o increase_n of_o blood_n as_o it_o do_v of_o milk_n by_o widen_v the_o vessel_n this_o be_v all_o mechanical_a truth_n that_o will_v answer_v upon_o experience_n as_o the_o most_o ingenious_a dr._n edw._n brown_n can_v witness_v who_o be_v the_o only_a man_n as_o far_o as_o i_o know_v that_o seem_v to_o have_v this_o practice_n 5._o it_o promote_v urine_n by_o the_o like_a open_n or_o relax_v of_o the_o pore_n of_o the_o kidney_n by_o its_o titillate_v volatile_a salt_n as_o cantharides_n bee_n pismire_n millepedes_n etc._n etc._n do_v 6._o it_o may_v probable_o be_v of_o great_a use_n in_o cutaneous_a distemper_n either_o by_o take_v large_a quantity_n of_o proper_a liquid_n and_o sweat_v they_o out_o again_o by_o its_o help_n to_o wash_v of_o ill_a particle_n or_o to_o open_v the_o pore_n for_o the_o admission_n of_o external_a medicament_n note_v that_o they_o be_v natural_a flux_n it_o promote_v and_o unnatural_a one_o that_o it_o stop_v which_o prove_v its_o operate_n as_o a_o entire_a friend_n to_o nature_n both_o way_n i._o the_o form_n may_v be_v which_o you_o please_v or_o be_v most_o agreeable_a to_o the_o patient_n ii_o the_o do_v moderate_a except_o it_o be_v when_o extraordinary_a relaxation_n or_o open_n of_o the_o pore_n be_v desire_v iii_o the_o vehicle_n shall_v be_v such_o as_o be_v proper_a to_o prepare_v the_o humour_n to_o pass_v by_o sweat_n or_o insensible_a perspiration_n or_o the_o blood_n by_o the_o menses_fw-la and_o lochia_n therefore_o shall_v general_o speak_v consist_v of_o attenuate_a thing_n as_o volatile_a spirit_n and_o in_o the_o plague_n venomous_a and_o contagious_a case_n of_o alexipharmack_n of_o diuretic_n to_o promote_v urine_n and_o so_o in_o all_o case_n of_o what_o be_v proper_a in_o the_o respective_a humour_n for_o their_o exit_fw-la or_o passage_n iv_o the_o time_n because_o sleep_n conduce_v to_o open_v the_o pore_n may_v be_v at_o the_o due_a distance_n before_o bedtime_n but_o that_o hinder_v not_o but_o it_o may_v be_v give_v when_o there_o be_v occasion_n at_o any_o other_o time_n in_o the_o plague_n it_o shall_v be_v so_o often_o give_v as_o to_o keep_v the_o pore_n always_o open_a mayern_n glve_v a_o instance_n of_o a_o physician_n that_o have_v all_o sign_n of_o death_n petechiae_fw-la a_o carbuncle_n etc._n etc._n who_o recover_v by_o take_v laudanum_n 6_o time_n a_o day_n i_o suppose_v 24_o hour_n or_o the_o natural_a day_n be_v mean_v thereby_o v._o the_o regimen_n must_v be_v such_o as_o be_v proper_a convenient_a and_o usual_a in_o the_o respective_a case_n for_o it_o be_v endless_a to_o mention_v all_o it_o require_v a_o volume_n to_o cause_n sweat_n much_o temperate_a liquid_n must_v be_v always_o give_v especial_o in_o fever_n or_o dry_a body_n as_o the_o hypochondriacal_a etc._n etc._n most_o part_n of_o the_o liquid_n shall_v be_v give_v before_o the_o opiate_n that_o they_o may_v have_v time_n to_o get_v into_o the_o blood_n by_o that_o time_n the_o opiate_n operate_v which_o do_v so_o as_o be_v show_v while_o it_o be_v at_o stomach_n to_o move_v the_o menses_fw-la proper_a mean_n shall_v be_v use_v for_o a_o due_a time_n before_o the_o use_v thereof_o because_o the_o effect_v expect_v in_o this_o case_n from_o opiate_n be_v only_o to_o open_v the_o way_n or_o pore_n so_o humour_n in_o leucophlegmatia_n &c._n &c._n shall_v be_v due_o prepare_v for_o the_o like_a reason_n to_o cause_n perspiration_n it_o be_v convenient_a in_o cold_a constitution_n and_o old_a people_n gentle_o to_o warm_v the_o blood_n with_o 2_o or_o 3_o glass_n of_o generous_a wine_n a_o little_a garlic_n onion_n selery_n or_o the_o like_a to_o attenuate_v and_o cause_v evaporation_n which_o heat_v promote_v but_o if_o you_o overheat_v the_o blood_n it_o hinder_v perspiration_n by_o its_o grow_a grievous_a for_o what_o be_v so_o cause_v contraction_n and_o close_n of_o the_o pore_n note_v that_o nothing_o can_v be_v so_o good_a to_o cause_v perspiration_n or_o sweat_n because_o it_o not_o only_o open_v the_o pore_n but_o take_v away_o any_o grievous_a passion_n or_o sensation_n that_o may_v close_v they_o and_o atenuate_v resolve_n etc._n etc._n by_o its_o volatile_a salt_n chap._n xxxviii_o of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n as_o a_o titillative_a this_o it_o do_v as_o be_v show_v by_o its_o volatile_a salt_n as_o cantharides_n bee_n pismire_n sem._n viril_n etc._n etc._n therefore_o 1._o it_o be_v of_o great_a use_n to_o excite_v to_o venery_n cause_n erection_n to_o actuate_v a_o dull_a semen_n for_o the_o sake_n of_o lawful_a propagation_n 2._o to_o increase_v the_o semen_n 1._o by_o the_o titillation_n of_o the_o venereal_a part_n which_o invite_v it_o thither_o by_o the_o agitation_n thereof_o as_o frication_n of_o the_o breast_n and_o those_o part_n cause_n increase_n of_o milk_n and_o the_o semen_n 2._o by_o the_o pleasure_n thereof_o relax_v the_o part_n which_o cause_v a_o great_a flux_n of_o it_o as_o of_o milk_n to_o the_o breast_n and_o nourishment_n to_o any_o part._n it_o be_v observable_a how_o desirous_a rachel_n be_v barren_a be_v of_o the_o opiate_n call_v mandrake_n so_o that_o she_o part_v with_o her_o belove_a husband_n to_o her_o sister_n leah_n for_o a_o night_n to_o purchase_v it_o whether_o it_o be_v any_o mean_n to_o cause_v she_o to_o conceive_v which_o she_o do_v afterward_o be_v not_o to_o be_v determine_v though_o it_o seem_v not_o altogether_o unlikely_a 3._o it_o be_v use_n to_o increase_v milk_n be_v speak_v of_o in_o the_o chapter_n of_o its_o use_n to_o relax_v only_o it_o do_v it_o here_o as_o titillate_v and_o there_o as_o relax_v 4._o it_o conduce_v to_o move_v the_o menses_fw-la by_o its_o titillation_n 5._o the_o titillation_n of_o its_o volatile_a salt_n as_o cantharides_n etc._n etc._n do_v move_v we_o to_o urine_n i._o the_o form_n be_v whole_o indifferent_a ii_o the_o dose_n must_v be_v large_a and_o general_o great_a than_o any_o i_o have_v mention_v and_o possible_o require_v a_o repetition_n thereof_o to_o excite_v to_o venery_n though_o i_o shall_v not_o prescribe_v any_o more_o than_o i_o have_v in_o the_o table_n of_o dose_n but_o leave_v it_o to_o judicious_a physician_n to_o do_v as_o they_o think_v â—it_a where_o there_o be_v a_o just_a cause_n for_o its_o use_n which_o i_o will_v not_o expose_v to_o every_o lustful_a goat_n it_o be_v not_o unlikely_a but_o one_o great_a cause_n of_o the_o ignorance_n of_o its_o use_n to_o excite_v venery_n in_o these_o western_a part_n of_o the_o world_n may_v be_v the_o smallness_n of_o the_o dose_n that_o we_o use_v beside_o the_o reason_n mention_v in_o chap._n 8._o and_o that_o such_o circumstance_n may_v occasion_v the_o dispute_n and_o contradiction_n that_o have_v be_v about_o the_o effect_n of_o opium_n whereas_o there_o be_v
chapter_n of_o its_o use_n to_o cause_v sleep_n v._o the_o regimen_n must_v be_v exact_a temperance_n and_o moderation_n in_o all_o thing_n and_o 1._o as_o to_o diet_n let_v it_o be_v appropriate_v to_o the_o disease_n and_o always_o of_o such_o thing_n as_o the_o stomach_n digest_v without_o any_o difficulty_n or_o disturbance_n 2_o as_o to_o sleep_v it_o shall_v be_v moderate_a yet_o so_o much_o as_o full_o recruit_n and_o refresh_v 3._o as_o to_o rest_n and_o motion_n the_o like_a moderation_n must_v be_v use_v for_o motion_n must_v not_o be_v violent_a or_o over-wasting_a of_o the_o spirit_n in_o any_o respect_n yet_o must_v gentle_a motion_n and_o exercise_n be_v use_v ride_v on_o horseback_n to_o such_o as_o can_v do_v it_o be_v a_o very_a wholesome_a exercise_n 4._o as_o to_o excretion_n and_o retension_n you_o shall_v never_o purge_v or_o vomit_n during_o its_o use_n unless_o there_o be_v a_o very_a special_a cause_n and_o then_o i_o will_v have_v the_o vomit_n to_o be_v only_o carduate_v water_n and_o for_o stool_n only_o so_o much_o of_o the_o scot_n pill_n or_o stomach_n pill_n as_o will_v serve_v to_o open_v the_o body_n to_o be_v take_v at_o bedtime_n or_o at_o such_o time_n of_o the_o night_n as_o to_o cause_v no_o disturbance_n before_o you_o be_v up_o in_o the_o morning_n but_o general_o speak_v cause_v not_o evacuation_n be_v best_a but_o what_o be_v the_o consequence_n of_o the_o panacea_fw-la itself_o which_o cause_v the_o best_a most_o natural_a universal_a and_o considerable_a evacuation_n by_o the_o pore_n 5._o as_o to_o the_o air_n the_o dry_a and_o temperate_a as_o to_o heat_n and_o cold_a but_o rather_o incline_v to_o coldness_n be_v the_o best_a for_o you_o can_v so_o well_o err_v on_o this_o hand_n because_o the_o pore_n will_v be_v keep_v open_a and_o cold_n prevent_v in_o a_o high_a manner_n by_o the_o use_n of_o the_o panacea_fw-la beside_o that_o coolness_n be_v most_o agreeable_a to_o digestion_n 6._o as_o to_o passion_n of_o the_o mind_n all_o the_o grievous_a one_o shall_v be_v avoid_v and_o a_o fine_a even_a cheerfulness_n maintain_v as_o mâ—ch_v as_o may_v be_v it_o will_v be_v very_o easy_o continue_v by_o the_o help_n of_o the_o panacea_fw-la which_o cause_v it_o above_o all_o thing_n 1._o note_v that_o these_o direction_n do_v general_o concern_v its_o use_n in_o chronical_a case_n for_o as_o to_o acute_a disease_n and_o particular_a gas_n it_o must_v be_v leave_v to_o the_o management_n of_o the_o present_a physician_n 2._o note_v that_o its_o use_n as_o a_o evacuative_a have_v be_v sufficient_o treat_v of_o in_o the_o chapter_n of_o its_o use_n to_o cause_v flux_n and_o evacuation_n 3._o note_n that_o notwithstanding_o all_o i_o have_v say_v of_o the_o most_o excellent_a qualification_n of_o the_o panacea_fw-la of_o opium_n i_o submit_v all_o to_o far_a experience_n at_o the_o introduction_n of_o which_o i_o main_o aim_v by_o endeavour_v to_o take_v off_o people_n fear_n and_o jealousy_n which_o have_v ever_o be_v the_o great_a hinderer_n of_o improvement_n in_o cure_n more_o especial_o in_o reference_n to_o the_o use_v of_o opiate_n which_o without_o doubt_n will_v cure_v many_o disease_n more_o than_o ever_o they_o be_v use_v for_o at_o least_o as_o alteratives_n which_o if_o my_o discourse_n do_v occasion_n i_o shall_v thank_v and_o praise_v the_o author_n of_o all_o good_a for_o make_v i_o instrumental_a thereto_o chap._n xli_o of_o the_o external_n use_v of_o opium_n it_o be_v external_n use_v be_v as_o the_o internal_a either_o i._o as_o a_o pleaser_n of_o sensation_n or_o a_o opiate_n spe_fw-mi cial_o so_o call_v or_o ii_o as_o a_o alterative_a first_o as_o a_o pleaser_n of_o sensation_n or_o a_o opiate_n proper_o and_o special_o so_o call_v it_o be_v scarce_o worth_a while_n to_o treat_v of_o it_o because_o of_o the_o uncertainty_n ineffectualness_n and_o sometime_o danger_n thereof_o unless_o it_o be_v to_o caution_n man_n concern_v it_o for_o my_o part_n i_o seldom_o or_o never_o use_v it_o external_o unless_o it_o be_v in_o venice-treacle_n diascordium_n or_o mithridate_n which_o have_v but_o little_a quantity_n thereof_o nor_o can_v i_o see_v why_o it_o shall_v be_v at_o all_o use_v external_o as_o a_o opiate_n except_o it_o be_v when_o opiate_n can_v be_v use_v internal_o where_o they_o have_v more_o even_o certain_a and_o better_a effect_n or_o in_o very_o â—ew_a case_n which_o will_v be_v mention_v the_o main_a therefore_o that_o i_o can_v do_v in_o this_o case_n be_v to_o acquaint_v you_o what_o other_o have_v sound_a by_o experience_n concern_v its_o external_a use._n 1._o it_o have_v be_v find_v dangerous_a to_o apply_v opiate_n to_o the_o suture_n of_o the_o head_n it_o have_v kill_v some_o and_o galen_n be_v against_o it_o l._n 2._o de_fw-fr comp._n med._n i_o have_v somewhere_o read_v of_o a_o man_n who_o after_o a_o certain_a contest_v for_o victory_n be_v very_o hot_a take_v off_o his_o helmet_n to_o refresh_v himself_o after_o the_o victory_n he_o have_v obtain_v which_o helmet_n his_o emulator_n smear_v on_o the_o inside_n with_o opium_n he_o afterward_o put_v it_o on_o and_o soon_o die_v 2._o it_o be_v apply_v more_o safe_o to_o the_o forehead_n or_o temple_n but_o the_o quantity_n of_o half_a a_o scruple_n shall_v not_o be_v exceed_v in_o this_o case_n fernelius_n commend_v the_o application_n of_o it_o to_o the_o forehead_n in_o headache_n frenzy_n &c_n &c_n mix_v with_o ointment_n wedelius_n do_v also_o use_n venice_n treacle_n and_o extract_v of_o opium_n to_o the_o temple_n with_o good_a success_n in_o pain_n of_o the_o head_n he_o also_o find_v the_o like_a success_n in_o apply_v it_o behind_o the_o ear_n note_v that_o the_o continuance_n and_o constancy_n of_o its_o operation_n where_o it_o take_v effect_v apply_v external_o may_v be_v very_o beneficial_a in_o some_o case_n but_o even_o that_o may_v be_v answer_v by_o internal_a use_n if_o it_o be_v repeat_v 3._o all_o or_o most_o do_v agree_v that_o it_o be_v too_o acrimonious_a to_o be_v apply_v to_o the_o eye_n 4._o geigâ—rus_n fernelius_n heurnius_n etc._n etc._n do_v commend_v its_o use_n to_o smell_v to_o be_v make_v into_o a_o ball_n etc._n etc._n with_o odoriferous_a thing_n and_o i_o have_v a_o opinion_n that_o this_o way_n of_o use_v it_o may_v be_v excellent_a condition_v that_o not_o above_o half_a a_o scruple_n of_o opium_n be_v use_v 1._o because_o but_o a_o small_a quantity_n and_o that_o of_o its_o fine_a part_n be_v thus_o receive_v into_o the_o body_n 2._o because_o it_o may_v be_v remove_v at_o pleasure_n and_o then_o as_o some_o say_v the_o effect_v immediate_o cease_v this_o be_v very_o well_o worth_a the_o experiment_n for_o it_o will_v be_v very_o neat_a to_o be_v able_a to_o cause_v sleep_n and_o its_o other_o effect_n with_o safety_n as_o long_o or_o as_o short_a a_o time_n as_o we_o please_v and_o no_o long_o for_o this_o can_v be_v do_v when_o it_o be_v internal_o give_v but_o its_o operation_n will_v have_v its_o course_n without_o extraordinary_a mean_n and_o trouble_n but_o when_o external_o use_v the_o very_a cause_n of_o the_o danger_n if_o any_o shall_v hâ—ppen_v can_v be_v immediate_o remove_v by_o take_v of_o the_o opiate_n from_o the_o nose_n 5._o that_o of_o geigerus_fw-la and_o langius_n use_v only_o one_o 〈◊〉_d of_o opium_n to_o the_o puncture_n or_o little_a wound_n make_v by_o a_o leecâ—_n behind_o the_o ear_n to_o cause_v sleep_n and_o that_o with_o effect_n seem_v to_o i_o to_o he_o attribute_v more_o to_o the_o bleed_a which_o always_o incline_v man_n to_o sleep_v than_o to_o the_o opium_n 6._o crude_a opium_n have_v kill_v people_n by_o put_v it_o in_o hollow_a tooth_n as_o some_o observer_n aver_v 7._o apply_v to_o the_o ear_n it_o relax_n and_o as_o it_o be_v resolve_v the_o tympan_n and_o other_o delicate_a membrane_n concern_v and_o thereby_o offend_v the_o hear_v 9_o galen_n seem_v to_o be_v against_o the_o application_n of_o it_o to_o the_o nape_n of_o the_o neck_n because_o so_o near_o the_o original_a of_o the_o nerve_n note_v that_o it_o be_v not_o convenient_a to_o use_v it_o where_o resolution_n and_o relaxation_n may_v do_v any_o harm_n as_o be_v say_v of_o the_o tympan_n of_o the_o ear_n etc._n etc._n 10._o venice_n treacle_n mithridate_n and_o diascordium_n be_v safe_o apply_v external_o to_o the_o region_n of_o the_o stomach_n to_o appease_v vomit_v and_o hiccough_n moderate_a looseness_n etc._n etc._n 11._o savanarola_n and_o octavius_n horatianus_n use_v it_o to_o the_o navel_n to_o cause_v sleep_n and_o with_o rue_n myrrh_n frankincense_n and_o wax_v to_o move_v to_o stool_n which_o it_o perform_v as_o the_o last_o mention_v author_n say_v 12._o silvius_n use_v it_o in_o his_o carminative_a plaster_n to_o discuss_v wind_n which_o be_v rational_a
13._o some_o of_o the_o ancient_n apply_v it_o to_o the_o perineum_n kidney_n region_n of_o the_o pubis_fw-la etc._n etc._n to_o chill_a venus_n by_o the_o cold_a quality_n they_o attribute_v to_o it_o which_o be_v all_o stuff_n ground_v upon_o that_o most_o absurd_a hypothesis_n 14._o they_o also_o attribute_v its_o psilothrick_n quality_n to_o cold_a than_o which_o nothing_o do_v more_o fasten_v and_o cause_v the_o hair_n to_o grow_v as_o you_o see_v in_o wintertime_n when_o all_o fur_n be_v long_o and_o fasten_v better_a to_o the_o skin_n into_o what_o foolery_n a_o false_a opinion_n will_v lead_v people_n 15._o it_o have_v be_v use_v by_o hieron_n mercurialis_n in_o ulcer_n of_o the_o womb_n with_o success_n and_o without_o danger_n as_o he_o say_v l._n 4._o de_fw-fr morb._n mul._n c._n 7._o p._n 281._o 16._o it_o have_v kill_v people_n in_o clyster_n by_o sâ—icking_v to_o the_o intestinum_fw-la rectum_fw-la which_o be_v doubtless_o by_o reason_n of_o its_o rosin_n for_o it_o have_v nothing_o in_o it_o beside_o the_o rosin_n that_o can_v stick_v to_o do_v any_o manner_n of_o harm_n which_o be_v a_o most_o demonstrative_a reason_n of_o the_o perniciousness_n of_o its_o rosin_n for_o if_o it_o can_v â—ill_v there_o much_o more_o where_o there_o be_v such_o exquisite_a sensation_n as_o be_v at_o stomach_n however_o it_o be_v know_v by_o experience_n that_o venice_n treacle_n and_o diascordium_n be_v because_o of_o the_o dissemination_n of_o the_o opium_n and_o smallness_n of_o the_o quantity_n safe_a in_o clyster_n and_o very_o useful_a in_o dysentery_n and_o diarrhaea_n as_o our_o panacea_fw-la must_v be_v that_o have_v no_o rosin_n in_o it_o and_o dissolvable_a in_o water_n or_o any_o humour_n of_o the_o body_n 17._o it_o may_v be_v use_v in_o suppository_n when_o the_o rosin_n be_v separate_v from_o it_o but_o i_o will_v not_o advise_v the_o use_n of_o above_o 4_o grain_n in_o this_o case_n or_o if_o 8_o or_o ten_o be_v use_v the_o suppository_n shall_v not_o remain_v long_o in_o the_o body_n this_o i_o say_v for_o caution_n sake_n 18._o it_o have_v be_v use_v reduce_v to_o a_o oointment_n or_o balsam_n with_o oil_n of_o rose_n etc._n etc._n to_o the_o sol_n of_o the_o â—eet_a to_o cause_v sleep_n with_o good_a success_n 〈◊〉_d polidamus_n l._n de_fw-fr doloribus_fw-la capitis_fw-la p._n 78._o 19_o d._n francisc._n hildesheâ—m_n assert_n that_o it_o take_v away_o pain_n in_o cautery_n â—ut_fw-la say_v it_o be_v apt_a to_o cause_n grangrens_n 20._o crollius_n in_o his_o basil._n chym._n p._n 235._o say_n that_o 2_o pill_n of_o opium_n each_o contain_n 8_o grain_n be_v put_v up_o into_o the_o nostril_n stop_v a_o desperate_a haemorrhage_n at_o nose_n but_o i_o shall_v hardly_o â—rust_v it_o in_o this_o case_n possible_o the_o blood_n may_v stop_v by_o some_o other_o cause_n a_o small_a deliquium_fw-la not_o observe_v or_o the_o like_a for_o deliquium_n still_o all_o motion_n by_o a_o sudden_a relaxation_n which_o as_o have_v be_v say_v suspend_v all_o humour_n and_o weaken_v the_o motion_n of_o the_o heart_n if_o it_o do_v not_o sometime_o quite_o take_v it_o off_o for_o the_o time_n second_o as_o a_o alterative_a emplostick_n &c_n &c_n it_o as_o be_v show_v incides_fw-la resolve_n discuss_n molleâ—ies_n maturate_n suppurate_n and_o be_v psilothrick_n and_o titillative_a therefore_o be_v of_o use_n 1._o in_o phlegmatic_a and_o oedematous_a tumor_n 2_o in_o windy_a tumor_n pain_n stitch_n etc._n etc._n 3._o to_o ripen_v boil_n bubo_n abscess_n and_o the_o like_a 4._o in_o all_o hard_a tumor_n of_o the_o spleen_n breast_n cancer_n tophousness_n etc._n etc._n in_o which_o case_n it_o be_v as_o other_o opiate_n be_v of_o excellent_a use_n by_o their_o powerful_a resolve_v and_o relax_v faculty_n 5._o to_o cause_v nourishment_n of_o part_n increase_v of_o milk_n etc._n etc._n by_o relaxation_n as_o sleep_v puberty_n pleasure_n etc._n etc._n do_v as_o have_v be_v show_v 6._o to_o cause_v the_o shed_n of_o hair_n by_o resolution_n of_o the_o part_n as_o by_o a_o caustick_a vesicatory_a etc._n etc._n with_o which_o it_o agree_v in_o its_o exulcerate_v faculty_n when_o it_o be_v very_o strong_a as_o the_o true_a maslach_n or_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d which_o we_o have_v not_o 7._o to_o excite_v to_o venery_n by_o its_o titillate_v volatile_a salâ—_n if_o apply_v to_o the_o perinaeum_n you_o bless_a mind_n who_o in_o a_o instant_n know_v what_o in_o five_o thousand_o year_n none_o here_o below_o can_v learn_v how_o mean_v be_v we_o how_o great_a be_v you_o o_o for_o your_o happy_a state_n while_o dull_a mankind_n oft_o see_v and_o fâ—el_v the_o thing_n they_o can_v find_v who_o do_v not_o see_v the_o blood_n move_v to_o and_o fro_o yet_o can_v none_o be_v circulation_n know_v till_o god_n enlighten_v harvey_n then_o do_v he_o perceive_v what_o other_o see_v can_v not_o see_v so_o till_o god_n be_v to_o my_o inquiry_n kind_a million_o seek_v and_o feel_v what_o they_o never_o can_v find_v what_o be_v vain_a man_n without_o the_o all_o know_a mind_n to_o who_o all_o glory_n be_v all_o thanks_o and_o praise_v as_o be_v be_v now_o and_o fit_a to_o be_v always_o amen_n amen_n amen_n finis_fw-la
we_o need_v not_o be_v solicitous_a only_o tell_v you_o that_o it_o have_v much_o of_o earth_n and_o water_n in_o it_o and_o more_o or_o less_o of_o that_o according_a to_o its_o foulness_n and_o of_o this_o according_a to_o its_o moistness_n or_o dryness_n and_o that_o it_o always_o have_v more_o water_n in_o it_o in_o moist_a wether_n for_o i_o never_o know_v any_o thing_n so_o apt_a to_o take_v in_o moisture_n and_o to_o alter_v according_o in_o its_o substance_n though_o not_o in_o virtue_n insomuch_o that_o i_o have_v use_v it_o as_o a_o indicator_n of_o the_o wether_n and_o it_o never_o sail_v to_o show_v the_o degree_n of_o moisture_n in_o the_o air_n if_o it_o be_v keep_v in_o a_o convenient_a place_n where_o accident_n as_o the_o sun_n fire_n etc._n etc._n may_v not_o alter_v the_o case_n and_o always_o in_o the_o same_o place_n our_o business_n therefore_o be_v to_o inquire_v after_o the_o active_a principle_n of_o opium_n i_o shall_v proceed_v in_o this_o plain_a and_o natural_a method_n v._o z._n i_o shall_v inquire_v 1._o which_o be_v the_o predominant_a active_a principle_n of_o opium_n and_o how_o combine_v etc._n etc._n 2._o which_o of_o they_o produce_v the_o good_a and_o laudable_a effect_n of_o opium_n and_o why_o 3._o which_o of_o they_o produce_v its_o ill_a effect_n and_o why_o 1._o as_o to_o its_o active_a principle_n which_o be_v predominant_a first_o it_o manifest_o appear_v that_o opium_n be_v high_o impregnate_v with_o volatile_a salt_n 1._o by_o its_o bite_n and_o pungent_a taste_n which_o be_v the_o certain_a effect_n of_o volatile_a salt_n as_o in_o mustard_n horseradish_n cress_n arum_fw-la or_o wake_v robin_n scurvigrass_n rochet_n spearwort_n crowsfoot_o squill_n radish_n arsmart_n onion_n garlic_n and_o very_o many_o plant_n of_o the_o same_o kind_a which_o have_v their_o bite_n and_o pungent_a taste_n as_o all_o know_v and_o allow_v from_o their_o volatile_a salt_n and_o so_o have_v all_o plant_n of_o the_o like_a taste_n which_o be_v therefore_o common_o esteem_v to_o be_v antiscorbutic_n 2._o by_o its_o rank_n and_o vehement_a smell_n be_v such_o as_o be_v by_o the_o common_a consent_n of_o the_o learned_a always_o attribute_v to_o volatile_a salt_n alone_o or_o join_v with_o some_o oily_a part_n as_o the_o smell_n of_o semen_n virile_a to_o which_o i_o take_v that_o of_o opium_n to_o be_v most_o like_a of_o burn_a hoof_n horn_n skin_n membrane_n etc._n etc._n garlick_n onion_n rocket_n pismire_n soot_n etc._n etc._n 3._o by_o its_o ready_a dissolution_n in_o water_n moist_a air_n etc._n etc._n which_o must_v be_v from_o its_o volatile_a salt_n because_o it_o have_v very_o little_o fix_v salt_n and_o because_o volatile_a salt_n be_v the_o most_o dissolvable_a salt_n that_o be_v in_o vegetable_n before_o they_o have_v pass_v the_o fire_n 4._o by_o its_o dissolution_n in_o spirit_n of_o wine_n which_o volatile_a salt_n be_v more_o apt_a to_o do_v than_o fix_a salt_n and_o this_o be_v one_o reason_n why_o it_o be_v so_o apt_a to_o dissolve_v in_o all_o menstruum_n especial_o the_o three_o main_a one_o viz._n the_o wâ—ry_n the_o salino-volatile_a as_o spirit_n of_o salt_n ammoniac_a spirit_n of_o hartshorn_n etc._n etc._n and_o the_o spirituosulphureous_a as_o spirit_n of_o wine_n brandy_n etc._n etc._n in_o which_o last_o thing_n its_o sulphur_n that_o be_v join_v with_o the_o volatile_a salt_n do_v much_o help_n it_o to_o dissolve_v 5._o by_o its_o incide_v and_o discuss_v quality_n when_o external_o apply_v which_o quality_n must_v be_v attribute_v to_o its_o volatile_a salt_n it_o have_v no_o other_o principle_n that_o can_v cause_v those_o quality_n especial_o in_o that_o eminent_a degree_n as_o opium_n have_v they_o and_o see_v it_o be_v not_o a_o thing_n that_o have_v undergo_v fermentation_n as_o vinous_a spirit_n and_o that_o it_o have_v but_o one_o in_o 32_o of_o the_o fix_a salt_n in_o its_o mass_n as_o the_o most_o excellent_a dr._n crew_n prove_v 6._o by_o its_o resolve_v quality_n be_v external_o apply_v for_o resolution_n be_v cause_v by_o such_o part_n as_o easy_o penetrate_v and_o mix_v with_o our_o skin_n flesh_n etc._n etc._n and_o such_o as_o do_v so_o must_v be_v of_o like_a active_a principle_n with_o our_o part_n for_o all_o know_v that_o easiness_n of_o mixture_n be_v by_o likeness_n of_o part_n and_o the_o active_a principle_n of_o our_o skin_n flesh_n etc._n etc._n be_v volatile_a salt_n join_v with_o some_o oily_a particle_n as_o have_v be_v say_v therefore_o opium_n must_v have_v such_o principle_n to_o be_v so_o great_a a_o resolver_n hence_o it_o be_v that_o gum_n ammoniacum_n hemlock_n and_o several_a gum_n plant_n etc._n etc._n that_o be_v saturate_v with_o volatile_a salt_n be_v such_o good_a resolver_n but_o it_o be_v worth_a a_o very_a particular_a remark_n that_o all_o narcotick_a plant_n be_v very_o eminent_a yea_o the_o very_o best_a resolver_n of_o hard_a tumour_n and_o the_o like_a as_o solanum_fw-la lethale_n or_o deadly_a nightshade_n hemlock_n henbane_n mandrake_n and_o the_o more_o narcotick_a they_o be_v the_o more_o resolve_v 7._o by_o its_o exulcerate_v or_o blister_a quality_n which_o be_v but_o a_o strong_a â—ort_n of_o resolution_n of_o part_n which_o the_o best_a and_o strong_a opium_n that_o be_v gather_v by_o drop_n out_o of_o the_o incision_n of_o the_o poppy_n head_n as_o author_n testify_v and_o the_o best_a we_o have_v as_o some_o say_v will_v do_v upon_o very_o tender_a skin_n or_o at_o least_o rubisy_n as_o mustard_n etc._n etc._n will_n which_o most_o evident_o prove_v its_o volatile_a salt_n for_o all_o blisterer_n as_o cantharides_n pismire_n crowsfoot_o spearwort_n garlick_n etc._n etc._n do_v it_o upon_o the_o account_n of_o their_o volatile_a salt_n unless_o it_o be_v lexiuâ—als_n which_o have_v pass_v the_o fire_n which_o opium_n have_v not_o 8._o it_o be_v offend_v the_o eye_n as_o onion_n mustard_n etc._n etc._n do_v when_o it_o be_v apply_v thereto_o argue_v its_o volatile_a salt_n note_v that_o the_o very_o best_a opium_n as_o the_o turk_n mastach_n etc._n etc._n do_v cause_n this_o effect_v most_o of_o all_o which_o manifest_o prove_v that_o the_o virtue_n of_o opium_n do_v main_o depend_v upon_o volatile_a salt_n which_o be_v most_o certain_o the_o cause_n of_o that_o effect_n of_o exulcerate_v or_o blister_v as_o all_o do_v allow_v in_o thing_n that_o have_v not_o pass_v the_o fire_n 9_o it_o be_v psilothrick_n quality_n prove_v the_o same_o for_o it_o cause_v the_o hair_n to_o fall_v by_o the_o same_o principle_n 10._o it_o be_v eminent_a titillation_n to_o venery_n as_o cantharides_n bee_n pismire_n sem._n virile_a garlic_n onion_n leek_n horse_n radish_n mustard_n rochet_n basil_n oyster_n bear_v garlic_n crow_n garlic_n etc._n etc._n do_v most_o infallible_o argue_v the_o abundance_n of_o its_o volatile_a salt_n by_o which_o those_o thing_n and_o all_o other_o plant_n that_o have_v much_o volatile_a salt_n excite_v to_o venery_n 11._o it_o be_v aptitude_n to_o evaporate_v and_o fly_v away_o argue_v its_o volatility_n 12._o it_o be_v cause_v a_o tickle_v and_o itch_a in_o the_o skin_n do_v most_o direct_o prove_v the_o same_o nor_o do_v any_o thing_n that_o be_v take_v inward_o cause_n it_o more_o it_o must_v have_v a_o very_a titillate_v volatile_a salt_n that_o will_v in_o so_o small_a a_o quantity_n as_o opium_n be_v usual_o take_v cause_v such_o violent_a itch_n as_o it_o do_v in_o the_o skin_n after_o it_o have_v pass_v all_o digestion_n and_o concoction_n 13._o it_o be_v bitterness_n prove_v the_o same_o for_o the_o curious_a and_o most_o perspicacious_a dr._n grew_n say_v that_o bitterness_n proceed_v from_o sulphur_n well_o impregnate_v with_o alcaline_a or_o acid_a salt_n shackle_a with_o earth_n but_o it_o be_v certain_a that_o it_o be_v not_o a_o acid_n in_o opium_n for_o the_o many_o reason_n give_v and_o to_o be_v add_v he_o also_o say_v that_o when_o sulphur_n and_o the_o alcaline_a be_v more_o equal_a they_o produce_v a_o tawny_a colour_n and_o opium_n rude_o tear_v be_v tawny_a till_o the_o air_n alter_v it_o all_o which_o silvius_n confirm_v where_o he_o say_v pran_n med._n l._n ii_o cap._n xxvi_o 80._o omnia_fw-la amara_fw-la volatili_fw-la sale_n abundant_a ad_fw-la quod_fw-la constituendum_fw-la oleum_fw-la quoque_fw-la concurrit_fw-la sive_fw-la sulphur_n that_o be_v all_o bitter_a thing_n abound_v with_o volatile_a salt_n to_o constitute_v which_o oil_n or_o sulphur_n concur_v i_o can_v choose_v though_o i_o do_v not_o much_o depend_v upon_o authority_n in_o the_o general_a but_o value_v the_o assertion_n of_o such_o man_n by_o way_n of_o concurrence_n at_o least_o 14._o the_o acrimonious_a sweat_v that_o it_o cause_n prove_v the_o same_o 15._o it_o be_v also_o diuretic_n as_o and_o after_o the_o same_o manner_n with_o cantharides_n bee_n pismire_n millepedes_n scurvygrass_n horse_n radish_n etc._n etc._n that_o be_v
by_o titillation_n upon_o the_o account_n of_o the_o volatile_a salt_n which_o appear_v by_o its_o exciting_a to_o venery_n at_o the_o same_o time_n as_o all_o those_o volatiles_fw-la do_v 16._o it_o be_v cause_v vomit_n as_o it_o often_o do_v be_v a_o undoubted_a sign_n of_o its_o volatile_a salt_n for_o all_o vegetable_a vomit_n be_v such_o upon_o that_o account_n unless_o it_o be_v such_o as_o may_v move_v vomit_v mere_o by_o their_o be_v loathe_v or_o nauseated_a which_o only_o cause_v some_o particular_a person_n to_o vomit_v but_o such_o as_o be_v constant_a vomitory_n be_v so_o upon_o the_o account_n of_o their_o volatile_a salt_n as_o asaerabocea_n groundsil_n foxâ—loves_n squill_n etc._n etc._n give_v in_o a_o sufficient_a quantity_n 17._o it_o be_v lively_a effect_n as_o courage_n etc._n etc._n prove_v the_o same_o 18._o all_o author_n that_o have_v be_v curious_a do_v agree_v that_o opium_n abound_v with_o volatile_a salt_n as_o helmont_n lemery_n le_fw-fr febure_n wedelius_n and_o indeed_o every_o one_o that_o ever_o i_o read_v though_o most_o of_o they_o attribute_v its_o effect_n to_o a_o sulphur_n which_o make_v their_o testimony_n of_o its_o volatile_a salt_n the_o strong_a as_o be_v force_v to_o confess_v it_o against_o their_o hypothesise_n 19_o after_o its_o fermentation_n with_o leaven_n in_o a_o sand_n heat_v for_o 14_o day_n it_o afford_v a_o volatile_a salt_n in_o good_a quantity_n but_o mix_v with_o oil_n which_o be_v separate_v from_o it_o by_o dissolution_n in_o water_n filtring_n etc._n etc._n 20._o it_o be_v spirit_n ferment_n with_o acid_n therefore_o be_v volatile_a last_o to_o pin_n up_o all_o if_o you_o either_o chemical_o analyse_v it_o by_o fire_n or_o set_v it_o to_o crystalize_v after_o it_o be_v evaporate_v to_o a_o due_a condition_n so_o to_o do_v it_o afford_v a_o great_a quantity_n of_o volatile_a salt_n therefore_o it_o be_v pass_v all_o manner_n of_o doubt_n for_o which_o end_n i_o have_v the_o long_o and_o more_o particular_o insist_v upon_o this_o point_n that_o it_o be_v high_o impregnate_v with_o volatile_a salt_n but_o as_o i_o say_v in_o the_o last_o chapter_n it_o be_v not_o enough_o for_o it_o to_o have_v volatile_a salt_n but_o it_o must_v be_v such_o as_o exceed_v our_o own_o or_o other_o animal_n in_o activity_n briskness_n etc._n etc._n by_o reason_n of_o quantity_n or_o quality_n or_o both_o that_o it_o may_v tickle_v up_o excite_v and_o cause_v a_o fine_a and_o agreeable_a ovation_n or_o glow_v in_o our_o spirit_n which_o as_o be_v show_v be_v very_o pleasant_a as_o in_o the_o case_n of_o sem._n viril_n especial_o when_o agitate_a by_o warmth_n frication_n or_o such_o actuate_a cause_n second_o it_o manifest_o appear_v that_o the_o volatile_a salt_n of_o opium_n exceed_v we_o in_o activity_n briskness_n etc._n etc._n 1._o by_o its_o exulcerate_v or_o blister_v quality_n especial_o if_o it_o be_v very_o good_a opium_n 2._o by_o its_o psilothrick_n quality_n to_o cause_v the_o hair_n to_o shed_v 3._o by_o its_o irritate_v to_o venery_n in_o so_o eminent_a a_o degree_n as_o cantharides_n bee_n pismire_n etc._n etc._n do_v and_o even_o beyond_o the_o ordinary_a course_n of_o sem._n virile_a which_o be_v most_o saturate_v with_o volatile_a salt_n of_o any_o part_n of_o the_o animal_n as_o appear_v by_o its_o dissolution_n like_o opium_n in_o watery_a menstruum_n its_o rank_a smell_n its_o titillate_v to_o venery_n its_o weight_n etc._n etc._n which_o be_v much_o the_o same_o with_o that_o of_o opium_n both_o sink_v in_o water_n etc._n etc._n 4._o by_o its_o great_a irritation_n to_o make_v water_n like_o cantharides_n bee_n pismire_n millepedes_n etc._n etc._n when_o it_o be_v take_v in_o a_o good_a quantity_n or_o often_o 5._o by_o its_o cause_v vomit_n in_o a_o very_a severe_a manner_n which_o it_o will_v not_o do_v without_o a_o very_a poignant_a volatile_a salt_n 6._o by_o its_o cause_v such_o violent_a itch_n in_o the_o skin_n especial_o if_o take_v in_o any_o quantity_n after_o it_o have_v pass_v all_o digestion_n and_o concoction_n and_o 7._o by_o its_o cause_v acrimonious_a sweat_v after_o it_o have_v pass_v those_o digestion_n and_o concoction_n 8._o by_o its_o cause_v a_o very_a pleasant_a sensation_n at_o stomach_n far_o above_o any_o flesh_n jelly_n or_o any_o animal_n nutriment_n 9_o by_o its_o offend_v the_o eye_n so_o much_o by_o its_o acrimony_n as_o mustard_n onion_n horse_n radish_n etc._n etc._n do_v 10._o by_o its_o very_a pungent_a and_o acrimonious_a taste_n above_o all_o flesh_n or_o fish_n 11._o by_o its_o very_a rank_n and_o vehement_a scent_n equal_a to_o if_o not_o exceed_v that_o of_o semen_n virile_a 12._o by_o its_o chemical_a analysis_n whereby_o it_o afford_v a_o very_a acrimonious_a volatile_a salt_n in_o great_a plenty_n which_o helmont_n wedelius_n and_o other_o do_v confirm_v therefore_o it_o be_v also_o past_a doubt_n that_o the_o volatile_a salt_n of_o opium_n be_v more_o active_a acrimonious_a and_o titillate_v than_o those_o in_o our_o membrane_n or_o in_o sem._n virile_a itself_o but_o see_v it_o be_v not_o volatile_a salt_n alone_o as_o be_v show_v which_o agree_v only_o with_o one_o of_o the_o active_a principle_n of_o our_o membrane_n and_o may_v be_v and_o be_v of_o itself_o too_o acrimonious_a and_o rude_a for_o the_o membrane_n without_o its_o be_v sweeten_v up_o and_o smooth_v into_o a_o more_o gentle_a and_o please_a agreeableness_n by_o oily_a part_n we_o must_v see_v whether_o it_o be_v not_o also_o oily_a or_o sulphureous_a and_o consequent_o a_o sal-volatile-oleosum_a agree_v in_o both_o the_o active_a principle_n of_o our_o membrane_n that_o it_o may_v thereby_o be_v the_o more_o delectable_a gentle_a and_o agreeable_a three_o it_o be_v very_o obvious_a and_o evident_a that_o opium_n be_v sulphureous_a 1._o because_o the_o juice_n of_o the_o poppy_n whereof_o it_o be_v make_v be_v of_o itself_o when_o it_o drop_n out_o of_o the_o incision_n milkwhite_a which_o colour_n in_o liquid_n especial_o the_o juice_n of_o plant_n proceed_v from_o sulphureous_a particle_n mix_v with_o water_n or_o phlegm_n as_o milk_n emulsion_n chyle_n cinnamon_n water_n and_o the_o tincture_n of_o all_o sulphureous_a thing_n drop_v into_o water_n do_v evince_n 2._o because_o it_o be_v inflammable_a for_o nothing_o be_v so_o but_o what_o be_v sulphureous_a 3._o because_o opium_n will_v soften_v with_o a_o dry_a warmth_n which_o all_o and_o only_o sulphureous_a thing_n will_v do_v as_o all_o rosin_n tallow_n pitch_v turpentine_n oil_n and_o such_o sulphureous_a thing_n 4._o because_o it_o be_v very_o bitter_a and_o that_o oleose_a particle_n be_v always_o as_o dr._n grow_v and_o silvius_n true_o say_v one_o ingredient_n of_o a_o bitter_a taste_n 5._o it_o be_v tawny_a colour_n do_v also_o as_o be_v say_v according_a to_o dr._n grow_v argue_v much_o sulphur_n 6._o it_o be_v hot_a taste_n prove_v the_o same_o for_o a_o proper_a hot_a taste_n be_v from_o sulphur_n as_o the_o bite_n or_o pungent_a be_v from_o volatile_a salt_n 7._o because_o of_o its_o pungent_a and_o strong_a smell_n which_o denote_v sulphur_n 8._o it_o be_v be_v so_o dissolvable_a as_o it_o be_v in_o spirit_n of_o wine_n brandy_n and_o other_o sulphureous_a menstruum_n prove_v the_o same_o 9_o it_o be_v dissolve_v quality_n argue_v that_o it_o have_v the_o same_o principle_n with_o our_o skin_n and_o flesh_n which_o be_v oleose_v as_o well_o as_o salino-volatile_a and_o that_o nothing_o be_v a_o complete_a dissolver_n but_o such_o as_o have_v both_o because_o agreeableness_n in_o principle_n be_v the_o basis_n of_o dissolution_n as_o you_o see_v in_o menstruum_n and_o the_o thing_n therein_o dissolve_v there_o be_v no_o good_a kind_a or_o complete_a dissolvent_a of_o our_o flesh_n etc._n etc._n but_o what_o participate_v of_o both_o because_o otherwise_o there_o will_v be_v a_o disagreement_n in_o one_o respect_n 10._o it_o appear_v by_o autopsie_n upon_o the_o chemical_a analysis_n of_o opium_n etc._n etc._n that_o it_o have_v a_o very_a considerable_a quantity_n of_o sulphur_n 11._o so_o if_o you_o only_o dissolve_v it_o in_o water_n you_o will_v find_v much_o sulphureous_a substance_n undissolved_a at_o the_o bottom_n 12._o all_o or_o most_o of_o the_o modern_a author_n attribute_v its_o operation_n to_o sulphur_n agree_v that_o it_o be_v well_o impregnate_v therewith_o therefore_o opium_n consist_v very_o much_o as_o to_o its_o active_a principle_n of_o a_o sal-volatile-sulphureum_a but_o still_o this_o do_v not_o complete_a a_o most_o agreeable_a sal-volatile-oleosum_a 1._o because_o it_o may_v be_v a_o sal-volatile-resinosum_a and_o yet_o be_v a_o sal-volatile-sulphureum_a 2._o if_o it_o be_v a_o sal-volatile-oleosum_a the_o oil_n and_o the_o volatile_a salt_n may_v be_v so_o disjoin_v as_o not_o to_o conspire_v and_o cooperate_v to_o please_v the_o membrane_n but_o act_n separately_z as_o oil_n and_o volatile_a salt_n give_v out_o of_o divers_a
leave_v that_o to_o other_o physician_n to_o please_v themselves_o or_o patient_n by_o add_v ambergrise_n musk_n saffron_n oil_n of_o cinnamon_n or_o other_o chemical_a oil_n sugar_n or_o the_o like_a according_a to_o their_o intent_n i_o have_v observe_v that_o as_o reason_n tell_v we_o its_o smell_n be_v best_a palliate_v by_o other_o rank_n smell_v as_o that_o of_o onion_n garlic_n asa-foetida_a etc._n etc._n and_o its_o bitter_a taste_n with_o bitter_a thing_n as_o gentian_n centaury_n etc._n etc._n therefore_o when_o person_n that_o know_v its_o smell_n and_o taste_n be_v aver_v to_o take_v it_o if_o the_o other_o more_o acceptable_a thing_n will_v not_o suffice_v for_o that_o purpose_n use_v some_o of_o these_o you_o may_v when_o you_o be_v in_o haste_n infuse_v half_o a_o dozen_o slice_n of_o gentian-root_n and_o one_o slice_v of_o a_o onion_n or_o a_o bruise_a clove_n of_o garlic_n or_o both_o in_o a_o glass_n of_o wine_n for_o one_o hour_n for_o a_o vehicle_n in_o that_o case_n it_o be_v better_o to_o infuse_v they_o long_o if_o you_o have_v time_n but_o you_o will_v find_v that_o the_o liquid_a panacea_fw-la have_v not_o such_o a_o mighty_a rank_a taste_n or_o smell_v but_o that_o it_o be_v easy_o palliate_v by_o such_o mean_n if_o the_o opium_n have_v no_o empyreum_fw-la the_o solid_a panacea_fw-la may_v be_v also_o palliate_v by_o the_o same_o thing_n convenient_o mix_v therewith_o i_o know_v there_o be_v other_o way_n and_o mean_n to_o separate_v the_o rosin_n etc._n etc._n as_o extract_v a_o tincture_n of_o opium_n in_o spirit_n of_o wine_n and_o afterward_o precipitate_v the_o rosin_n with_o distil_a rain-water_n but_o this_o be_v attend_v with_o more_o trouble_n and_o many_o inconvenience_n that_o be_v avoid_v by_o the_o cold_a distil_a rain-water_n for_o 1._o you_o know_v not_o how_o the_o spirit_n of_o wine_n may_v as_o be_v say_v alter_v it_o 2._o this_o be_v go_v round_o the_o bush_n and_o compound_v two_o menstruum_n together_o whereas_o the_o simple_a water_n use_v alone_o be_v much_o better_a 3._o you_o can_v thus_o separate_v the_o resinous_a particle_n so_o perfect_o by_o reason_n that_o the_o spirit_n of_o wine_n must_v retain_v some_o of_o they_o and_o if_o you_o add_v more_o and_o more_o water_n in_o the_o precipitation_n the_o tincture_n become_v too_o much_o dilute_v and_o very_o weak_a how_o much_o better_a be_v it_o to_o use_v a_o menstruum_fw-la that_o never_o take_v up_o any_o rosin_n and_o consequent_o need_v no_o such_o separation_n and_o labour_n of_o precipitation_n it_o be_v better_a not_o to_o admit_v a_o enemy_n to_o one_o country_n than_o afterward_o to_o endeavour_v his_o expulsion_n for_o he_o will_v at_o best_a leave_n some_o mark_n of_o his_o hostility_n behind_o he_o as_o the_o rosin_n will_v in_o the_o spirit_n of_o wine_n the_o like_a inconvenience_n there_o will_v be_v in_o separate_v it_o by_o the_o way_n of_o distillation_n as_o 1._o the_o alter_n of_o it_o by_o the_o tyranny_n of_o fire_n 2._o the_o loss_n of_o it_o by_o evaporation_n 3._o the_o addition_n of_o the_o particle_n of_o fire_n thereto_o 4._o the_o never_o separate_a it_o so_o well_o that_o way_n 5._o the_o disunit_a of_o the_o oil_n and_o volatile_a salt_n in_o some_o measure_n but_o what_o experience_n may_v hereafter_o teach_v man_n i_o will_v not_o determine_v neither_o can_v 1_n but_o this_o i_o can_v that_o as_o it_o be_v even_o miraculous_a that_o people_n shall_v never_o mind_v the_o cause_n they_o daily_o feel_v and_o solicitous_o seek_v for_o so_o it_o be_v as_o strange_a that_o they_o can_v not_o hit_v upon_o the_o plain_a use_n of_o water_n so_o very_o common_a in_o all_o hand_n for_o a_o menstruum_fw-la either_o by_o chance_n or_o consideration_n in_o all_o the_o eastern_a part_n of_o the_o world_n where_o it_o be_v so_o universal_o take_v or_o in_o the_o inquisitive_a western_a part_n of_o the_o world_n where_o it_o have_v be_v study_v and_o consider_v by_o great_a number_n with_o the_o utmost_a diligence_n but_o they_o pass_v over_o water_n as_o despicable_a because_o common_a for_o familiarity_n breed_v contempt_n though_o its_o be_v make_v the_o drink_n of_o all_o live_a creature_n by_o the_o omniscient_n shall_v commend_v it_o above_o all_o thing_n do_v like_o those_o that_o regardless_o pass_v over_o a_o jewel_n or_o treasure_n and_o have_v once_o leave_v it_o behind_o they_o proceed_v far_o and_o far_o from_o it_o the_o great_a progress_n they_o make_v conclude_v that_o it_o be_v not_o to_o be_v find_v the_o way_n they_o pass_v not_o because_o it_o be_v not_o there_o but_o because_o they_o can_v not_o see_v it_o as_o for_o the_o keep_n of_o the_o liquid_a panacea_fw-la uncorrupted_a i_o do_v not_o find_v it_o apt_a to_o change_v however_o because_o make_v so_o easy_o by_o bare_a throw_v it_o into_o water_n it_o need_v not_o be_v keep_v long_o but_o may_v be_v make_v upon_o all_o occasion_n or_o at_o least_o one_o under_o the_o other_o as_o the_o apothecary_n spend_v it_o who_o it_o be_v not_o improbable_a may_v by_o their_o great_a ingenuity_n and_o experience_n in_o those_o matter_n find_v other_o convenient_a mean_n to_o preserve_v it_o for_o their_o purpose_n chap._n xxvi_o of_o other_o preparation_n of_o opium_n that_o be_v absolute_o or_o tolerable_o safe_a in_o a_o moderate_a do_v i._o all_z preparation_n be_v very_o safe_a in_o a_o moderate_a do_v wherein_o the_o resinous_a part_n of_o the_o opium_n be_v whole_o separate_v from_o it_o such_o be_v all_o extract_v make_v in_o aqueous_a menstruum_n or_o any_o other_o that_o imbibe_v none_o of_o the_o resinous_a part_n of_o opium_n as_o the_o preparation_n that_o wedâ—lius_n have_v in_o his_o opiologia_fw-la l._n 1._o sect._n 2._o cap._n 5._o p._n 65._o which_o be_v extract_v out_o of_o phlegm_n of_o vinegar_n that_o remain_v after_o the_o preparation_n of_o arcanum_n tartari_fw-la so_o laudanum_n liquidum_fw-la cydoniatum_n and_o langelott_n laudanum_n if_o the_o resinous_a part_n be_v due_o separate_v be_v very_o safe_a and_o commendable_a for_o the_o like_a reason_n as_o be_v also_o le_fw-fr mort's_n extract_n out_o of_o rain-water_n diacodium_fw-la etc._n etc._n ii_o all_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n though_o not_o separate_v from_o it_o be_v so_o alter_v order_v divide_v etc._n etc._n as_o not_o to_o stick_v to_o the_o stomach_n and_o render_v digestible_a and_o passable_a out_o of_o it_o without_o offence_n may_v be_v safe_o use_v of_o this_o kind_n there_o be_v or_o may_v be_v two_o sort_n first_o such_o wherein_o the_o nature_n of_o the_o rosin_n be_v alter_v in_o some_o degree_n at_o least_o second_o such_o wherein_o though_o the_o nature_n of_o the_o rosin_n be_v not_o destroy_v yet_o be_v it_o so_o order_v divide_a etc._n etc._n as_o not_o to_o stick_v to_o the_o stomach_n but_o render_v digestible_a and_o passable_a without_o offence_n of_o the_o first_o sort_n be_v 1._o such_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n be_v quite_o alter_v in_o its_o form_n and_o nature_n by_o chemistry_n or_o artificial_a torture_n of_o fire_n which_o because_o hardly_o to_o be_v do_v without_o much_o impair_n the_o sal-volatile-oleosum_a will_v be_v neither_o commendable_a nor_o worth_a while_n consider_v how_o easy_o without_o that_o trouble_v pain_n and_o labour_n even_o the_o rosin_n itself_o may_v be_v separate_v whole_o from_o the_o opium_n by_o aqueous_a menstruum_n 2._o such_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n be_v alter_v and_o as_o it_o be_v soapify_v by_o lixivial_a salt_n or_o soap_n which_o ready_o engage_v and_o intimate_o join_v with_o the_o small_a resinous_a particle_n of_o the_o opium_n by_o long_a and_o strong_a pound_v they_o together_o in_o a_o mortar_n or_o otherwise_o as_o in_o matthew_n or_o starkey_n pill_n bates's_fw-fr pacifick_n pill_n etc._n etc._n by_o which_o mean_v those_o resinous_a particle_n become_v in_o a_o great_a degree_n at_o least_o if_o not_o whole_o miscible_a with_o and_o so_o dissolvable_a and_o digestible_a in_o the_o liquor_n we_o drink_v and_o easy_o subduable_a by_o the_o menstruum_fw-la at_o stomach_n out_o of_o which_o it_o also_o easy_o pass_v by_o reason_n of_o the_o great_a slipperiness_n it_o acquire_v which_o also_o prevent_v its_o stick_n by_o that_o intimate_a mixture_n with_o the_o soap_n or_o lixivial_n therefore_o i_o take_v those_o pill_n of_o matthews_n and_o dr._n bates_n to_o be_v safe_a preparation_n though_o not_o to_o be_v compare_v to_o the_o panacea_fw-la wherein_o all_o danger_n and_o its_o cause_n be_v quite_o take_v away_o by_o whole_o separate_v the_o resinous_a part_n earth_n and_o filth_n of_o the_o opium_n from_o its_o sal-volatile-oleosum_a and_o doubtless_o have_v maththews_n starkey_n and_o bates_n know_v that_o the_o rosin_n of_o opium_n have_v be_v the_o cause_n of_o its_o ill_a effect_n they_o will_v never_o
have_v spend_v month_n in_o prepare_v the_o sapo_n tartareus_fw-la to_o correct_v opium_n when_o they_o may_v with_o the_o hundred_o part_n of_o the_o trouble_v and_o forty_o part_n of_o the_o time_n whole_o have_v take_v away_o the_o pernicious_a part_n by_o aqueous_a menstruum_n which_o they_o only_o pretend_v to_o correct_v by_o the_o sapo_n tartareus_fw-la though_o i_o allow_v it_o for_o the_o reason_n aforesaid_a to_o be_v a_o good_a corrector_n yet_o can_v it_o equal_v the_o total_a separation_n of_o the_o pernicious_a part_n i_o be_o of_o opinion_n upon_o my_o best_a thought_n and_o some_o experience_n that_o intimate_o mix_v and_o subdue_a opium_n with_o good_a white_a soap_n may_v for_o the_o reason_n aforesaid_a prove_v a_o good_a and_o ready_a corrector_n or_o preventer_n of_o the_o adhesion_n of_o the_o resinous_a part_n of_o opium_n to_o the_o stomach_n much_o conduce_v to_o its_o dissolution_n or_o digestion_n therein_o and_o nimble_a slip_n out_o of_o it_o and_o thereby_o prevent_v all_o the_o ill_a effect_n of_o opium_n which_o it_o cause_v by_o the_o adhesion_n and_o indigestibleness_n of_o its_o rosin_n of_o the_o second_o sort_n of_o preparation_n of_o opium_n wherein_o its_o rosin_n remain_v whole_o unaltered_a in_o its_o nature_n yet_o become_v safe_a by_o divide_v it_o etc._n etc._n this_o be_v main_o if_o not_o altogether_o do_v by_o a_o fine_a and_o through_o division_n of_o the_o resinous_a part_n of_o opium_n and_o keep_v they_o afterward_o from_o a_o coalescence_n in_o and_o adhesion_n to_o the_o stomach_n by_o which_o mean_n they_o become_v digestible_a or_o at_o least_o passable_a without_o offence_n this_o may_v be_v do_v 1._o by_o torrefaction_n till_o the_o opium_n be_v very_o friable_a and_o then_o fine_o powder_a it_o and_o mix_v it_o with_o such_o thing_n as_o be_v of_o good_a consistence_n etc._n etc._n to_o keep_v the_o part_n of_o opium_n from_o a_o coalescence_n as_o in_o venice_n treacle_n mithridate_n diascordium_n the_o philonium_n etc._n etc._n this_o be_v the_o way_n and_o method_n that_o the_o ancient_n use_v which_o cause_v galen_n to_o say_v that_o opium_n alone_o that_o be_v undivided_a and_o unmixed_a with_o other_o thing_n to_o prevent_v its_o coalescence_n etc._n etc._n be_v dangerous_a but_o mix_v with_o other_o thing_n be_v salutiferous_a which_o they_o find_v by_o experience_n not_o know_v the_o cause_n but_o attribute_v the_o safety_n thereof_o to_o something_o among_o the_o many_o ingredient_n as_o a_o corrector_n of_o the_o opium_n hence_o it_o be_v that_o they_o put_v small_a quantity_n thereof_o into_o electuary_n make_v of_o many_o and_o much_o other_o thing_n that_o keep_v the_o particle_n asunder_o which_o they_o do_v so_o common_o that_o at_o last_o all_o electuary_n be_v call_v opiate_n thus_o we_o have_v those_o composition_n above_o name_v which_o be_v safe_o use_v for_o the_o reason_n aforesaid_a not_o that_o any_o thing_n therein_o correct_v i_o know_v not_o what_o poisonous_a or_o narcotick_a quality_n in_o opium_n but_o that_o the_o other_o ingredient_n divide_v its_o rosin_n and_o afterward_o keep_v its_o particle_n from_o coalescence_n and_o adhesion_n 2._o dissolution_n of_o opium_n in_o spirit_n of_o wine_n or_o such_o sulphureous_a spirit_n which_o fine_o divide_v the_o rosin_n and_o use_v the_o bare_a tincture_n before_o the_o resinous_a particle_n be_v again_o compact_v as_o in_o extract_n etc._n etc._n may_v be_v of_o use_n if_o due_o administer_v but_o here_o a_o caution_n be_v to_o be_v use_v that_o you_o take_v it_o not_o in_o or_o drink_v any_o aqueous_a or_o phlegmatic_a liquid_a with_o it_o or_o before_o or_o after_o it_o in_o two_o or_o three_o hour_n which_o if_o you_o do_v the_o resinous_a particle_n will_v be_v precipitate_v thereby_o and_o so_o stick_v to_o the_o bottom_n tom_fw-mi of_o the_o stomach_n cause_v thereby_o the_o usual_a ill_a effect_n of_o vomit_v anxiety_n etc._n etc._n therefore_o it_o shall_v be_v give_v only_o in_o a_o spirituous_a liquid_a note_v also_o that_o if_o you_o give_v a_o solution_n thereof_o in_o any_o lixivium_n you_o take_v care_v not_o to_o dilate_v it_o by_o any_o mean_n by_o aqueous_a liquid_n in_o two_o hour_n before_o or_o after_o you_o take_v it_o for_o then_o there_o be_v but_o little_a lixivial_a salt_n in_o proportion_n to_o the_o liquid_a the_o resinous_a part_n be_v let_v go_v and_o precipitate_v to_o the_o bottom_n of_o the_o stomach_n as_o in_o the_o case_n of_o the_o spirit_n of_o wine_n so_o dilate_v of_o which_o i_o have_v see_v a_o very_a convince_a instance_n for_o one_o that_o have_v a_o esteem_n of_o lixivial_o in_o this_o case_n not_o only_o according_a to_o helmont_n and_o the_o common_a cry_n to_o correct_v opium_n but_o also_o to_o extract_v its_o virtue_n the_o more_o effectual_o make_v a_o tincture_n of_o opium_n in_o water_n lixiviate_v with_o salt_n of_o wormwood_n whereof_o he_o take_v the_o quantity_n that_o he_o have_v see_v i_o give_v of_o my_o liquid_a panacea_fw-la in_o a_o coffee-dish_n full_a of_o water_n which_o precipitate_v the_o rosin_n in_o the_o stomach_n cause_v he_o to_o vomit_v in_o about_o a_o hour_n after_o and_o continue_v so_o to_o do_v for_o about_o 15_o hour_n by_o which_o you_o plain_o see_v that_o the_o great_a secret_a of_o lixivial_o to_o correct_v opium_n lie_v mere_o in_o its_o division_n of_o the_o rosin_n thereof_o as_o in_o the_o case_n of_o spirit_n of_o wine_n and_o powder_a it_o and_o afterward_o keep_v its_o particle_n asunder_o during_o its_o stay_n at_o stomach_n which_o the_o sapo_n tartareus_fw-la do_v and_o probable_o other_o soap_n may_v do_v very_o well_o for_o the_o several_a reason_n aforesaid_a 3._o dissolution_n of_o opium_n in_o the_o yolk_n of_o a_o rear_n new_o lay_v egg_n by_o pound_v the_o dose_n that_o you_o intend_v to_o take_v with_o a_o little_a quantity_n of_o the_o yolk_n till_o both_o be_v thorough_o mix_v and_o then_o take_v it_o in_o the_o remain_a part_n of_o the_o yolk_n by_o which_o mean_v you_o not_o only_o fine_o divide_v the_o resinous_a part_n of_o the_o opium_n while_o the_o yolk_n of_o the_o egg_n intimate_o mix_v with_o they_o as_o it_o do_v with_o other_o rosin_n and_o turpentine_n but_o send_v along_o with_o it_o into_o the_o stomach_n what_o be_v digestible_a in_o itself_o and_o more_o and_o more_o divide_v and_o separate_v the_o resinous_a part_n and_o high_o contribute_v to_o their_o final_a dissolution_n and_o digestion_n so_o that_o i_o doubt_v not_o but_z you_o will_v find_v this_o new_a ready_a and_o agreeable_a mean_n as_o good_a if_o not_o better_o all_o thing_n consider_v than_o the_o former_a and_o even_o equal_a to_o the_o sapo_n tartareus_fw-la by_o what_o be_v say_v though_o short_a you_o may_v because_o it_o be_v the_o clear_a truth_n of_o thing_n judge_v of_o the_o goodness_n of_o all_o preparation_n of_o opium_n and_o 1._o that_o resinous_a thing_n shall_v not_o be_v add_v to_o opium_n because_o such_o like_o its_o own_o rosin_n render_v it_o more_o indigestible_a and_o apt_a to_o stick_v at_o stomach_n hence_o it_o be_v that_o the_o styrax_fw-mi pill_n have_v resinous_a thing_n in_o it_o and_o crude_a opium_n do_v so_o often_o cause_v dismal_a effect_n though_o forsooth_o much_o esteem_v for_o the_o lung_n cough_n defluxion_n etc._n etc._n for_o have_v such_o balsamic_a resinous_a thing_n as_o styrax_n and_o olibanum_n in_o it_o whereas_o the_o benefit_n be_v from_o the_o opium_n have_v dr._n bates_n know_v the_o cause_n of_o the_o mischief_n of_o opium_n he_o will_v never_o have_v put_v benjamin_n in_o his_o pacifick_n pill_n 2._o that_o all_o preparation_n make_v of_o extract_n in_o spirit_n of_o wine_n be_v to_o be_v reject_v such_o extract_v be_v much_o worse_a than_o crude_a opium_n and_o experimental_o find_v to_o be_v so_o therefore_o our_o common_a london_n laudanum_n be_v make_v of_o opium_n prepare_v in_o spirit_n of_o wine_n be_v no_o commendable_a preparation_n though_o so_o much_o use_v and_o cry_v up_o which_o also_o experience_n prove_v in_o that_o it_o sometime_o cause_v the_o ill_a effect_n of_o opium_n when_o give_v alone_o in_o a_o good_a do_v you_o will_v find_v more_o of_o these_o matter_n when_o you_o come_v to_o chap._n 29._o which_o consist_v of_o general_a rule_n and_o caution_n concern_v the_o use_n of_o opium_n therefore_o though_o i_o may_v add_v some_o useful_a observation_n i_o put_v a_o end_n to_o this_o matter_n at_o present_a for_o that_o reason_n and_o because_o what_o be_v to_o be_v true_o do_v in_o the_o preparation_n of_o opium_n be_v very_o evident_a from_o what_o be_v say_v since_o the_o cause_n of_o the_o ill_a effect_n of_o opium_n be_v now_o certain_o know_v to_o be_v its_o rosin_n to_o the_o separation_n or_o due_a alteration_n of_o which_o so_o as_o to_o cause_v it_o to_o pass_v the_o stomach_n without_o adhesion_n or_o offence_n by_o