of_o the_o muscle_n of_o the_o gut_n stomach_n tendon_n membrane_n and_o the_o like_a fibrose_n part_n natural_o resist_v distraction_n and_o have_v a_o power_n of_o contract_v themselves_o after_o extension_n yea_o more_o we_o see_v that_o all_o fibres_fw-fr even_o in_o their_o natural_a posture_n be_v somewhat_o upon_o the_o stretch_n for_o when_o they_o be_v cut_v they_o instant_o shorten_v themselves_o towards_o both_o end_n which_o will_v not_o happen_v if_o they_o have_v be_v constitute_v in_o a_o middle_a state_n betwixt_o laxity_n and_o extension_n as_o a_o bow_n unbend_v be_v quiet_a suffer_v neither_o contraction_n nor_o distraction_n of_o its_o part_n now_o if_o all_o fibre_n even_o in_o their_o natural_a state_n suffer_v some_o degree_n of_o stretch_v certain_o when_o the_o artery_n be_v replenish_v with_o blood_n their_o cavity_n must_v be_v dilate_v and_o in_o the_o dilatation_n of_o their_o cavity_n their_o transverse_n or_o circular_a fibre_n must_v suffer_v much_o 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he_o call_v it_o alacritatem_fw-la incogitatam_fw-la &_o injussam_fw-la that_o return_v to_o his_o mind_n upon_o the_o first_o sight_n of_o the_o restore_a light_n the_o same_o surprise_a alacrity_n methinks_v i_o now_o feel_v within_o myself_o after_o my_o passage_n through_o the_o no_o less_o darkness_n in_o which_o nature_n have_v through_o a_o long_a series_n of_o age_n involve_v her_o great_a secret_n of_o the_o motion_n of_o the_o heart_n make_v more_o obscure_a by_o the_o dust_n of_o man_n various_a opinion_n and_o my_o arrive_v at_o the_o light_n of_o knowledge_n both_o what_o be_v the_o proper_a action_n of_o the_o heart_n and_o by_o what_o mechanic_n necessity_n that_o action_n be_v perform_v in_o the_o ardour_n of_o this_o alacrity_n i_o proceed_v to_o the_o use_n and_o action_n of_o the_o ear_n of_o the_o heart_n and_o of_o its_o valve_n the_o end_n of_o the_o vena_fw-la cava_fw-la which_o be_v conjoin_v to_o the_o heart_n be_v as_o have_v be_v say_v before_o in_o great_a 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a_o very_a strong_a contexture_n of_o a_o triangular_a figure_n the_o base_n of_o which_o be_v close_o affix_v to_o the_o whole_a circuit_n of_o the_o tendon_n of_o the_o orifice_n of_o the_o heart_n then_o the_o areae_fw-la or_o middle_a space_n of_o these_o little_a membrane_n be_v branch_v within_o the_o ventricles_n of_o the_o heart_n into_o many_o little_a tendinose_n string_n or_o cord_n which_o be_v fasten_v to_o the_o top_n of_o the_o papillae_fw-la or_o teat_n that_o stand_v point_v upward_o place_v on_o the_o opposite_a side_n now_o this_o admirable_a structure_n be_v know_v let_v we_o inquire_v the_o design_n or_o use_v of_o it_o first_o the_o extreme_a part_n of_o the_o vena_fw-la cava_fw-la seem_v not_o to_o be_v make_v musculose_o for_o strength_n lest_o it_o shall_v be_v break_v by_o the_o current_n of_o the_o blood_n rush_v in_o but_o rather_o by_o its_o constriction_n to_o protrude_v the_o blood_n into_o the_o oblique_a sinus_n of_o the_o right_a ear_n and_o to_o render_v the_o same_o turgid_a which_o action_n be_v help_v by_o the_o peristaltic_a constriction_n of_o the_o whole_a trunk_n of_o the_o vena_fw-la cava_fw-la and_o by_o the_o compression_n of_o the_o muscle_n and_o viscera_n of_o the_o whole_a body_n as_o be_v yesterday_o demonstrate_v when_o we_o consider_v the_o motion_n of_o the_o blood_n hence_o it_o come_v that_o the_o blood_n impel_v through_o the_o open_a aperture_n of_o the_o ear_n fill_v the_o cavity_n of_o it_o and_o then_o run_v into_o the_o right_a ventricle_n and_o by_o the_o like_a necessity_n the_o blood_n flow_v out_o of_o the_o vena_fw-la pulmonaris_fw-la into_o the_o left_a ear_n and_o thence_o into_o the_o left_a ventricle_n of_o the_o heart_n no_o soon_o be_v the_o ear_n fill_v and_o distend_v with_o blood_n but_o they_o both_o at_o the_o same_o time_n constringe_v themselves_o by_o a_o contractive_a and_o compressive_a action_n common_a to_o all_o muscle_n resemble_v that_o of_o a_o press_n in_o this_o order_n that_o first_o by_o shut_v their_o aperture_n they_o hinder_v the_o regress_n of_o the_o blood_n into_o the_o same_o vein_n out_o of_o which_o it_o come_v in_o then_o by_o the_o great_a force_n of_o compression_n they_o squeeze_v it_o into_o the_o ventricles_n of_o the_o heart_n until_o they_o be_v fill_v and_o make_v turgid_a to_o this_o action_n of_o the_o ear_n immediate_o succeed_v the_o compression_n of_o the_o press_n of_o the_o heart_n itself_o by_o which_o the_o blood_n itself_o by_o reason_n of_o its_o abundance_n inflate_v and_o distend_v the_o triangular_a and_o mitral_a valve_n exact_o shut_v the_o orifice_n or_o mouth_n of_o the_o vein_n and_o so_o prevent_v its_o own_o recoil_n into_o they_o whence_o it_o be_v of_o absolute_a necessity_n that_o the_o same_o blood_n be_v express_v into_o the_o pulmonary_a artery_n or_o vena_fw-la arterialis_fw-la and_o into_o the_o aorta_fw-la these_o be_v the_o
carry_v on_o the_o resemblance_n a_o little_a far_o i_o soon_o discover_v the_o disparity_n to_o be_v so_o many_o and_o so_o great_a that_o it_o be_v impossible_a to_o reconcile_v they_o into_o a_o just_a analogy_n whereupon_o condemn_v the_o extravagance_n of_o my_o fancy_n i_o sober_o conclude_v that_o the_o heart_n of_o a_o animal_n be_v a_o engine_n never_o to_o be_v imitate_v by_o human_a art_n and_o i_o find_v myself_o more_o incline_v to_o applaud_v the_o judgement_n of_o that_o prodigy_n of_o mathematical_a knowledge_n archimedes_n of_o syracuse_n for_o never_o attempt_v to_o counterfeit_v the_o motion_n of_o the_o heart_n than_o to_o admire_v his_o wit_n show_v in_o make_v a_o sphere_n of_o glass_n athan._n 1._o kircher_n deny_v that_o any_o part_n of_o it_o be_v glass_n but_o only_o the_o outside_n that_o man_n may_v discern_v the_o wheel_n and_o motion_n within_o which_o represent_v the_o perfect_a order_n and_o motion_n of_o the_o celestial_a body_n and_o which_o claudian_n 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the_o first_o therefore_o viz._n the_o admirable_a motive_n force_v of_o the_o heart_n since_o the_o round_a and_o conical_a figure_n of_o the_o heart_n do_v not_o permit_v we_o to_o attempt_v the_o measure_n of_o its_o motive_n power_n by_o the_o same_o way_n by_o which_o the_o most_o learned_a alphonsus_n borellus_n have_v with_o singular_a sagacity_n measure_v the_o force_n of_o very_a many_o other_o muscle_n of_o man_n body_n namely_o by_o weight_n suspend_v by_o they_o and_o since_o therefore_o in_o this_o disquisition_n we_o can_v from_o the_o effect_n proceed_v to_o the_o knowledge_n of_o the_o cause_n we_o be_v compel_v from_o some_o other_o sign_n to_o raise_v a_o probable_a conjecture_n whence_o we_o may_v investigate_v the_o greatness_n of_o the_o effect_n and_o this_o sign_n shall_v be_v the_o similitude_n and_o analogy_n which_o the_o muscule_n of_o the_o heart_n seem_v to_o hold_v to_o other_o muscle_n of_o the_o same_o animal_n let_v we_o then_o with_o the_o same_o excellent_a mathematician_n borellus_n in_o who_o footstep_n i_o now_o again_o tread_v suppose_v that_o all_o even_o the_o least_o fibres_fw-fr or_o little_a machine_n of_o the_o same_o or_o divers_a muscules_n in_o the_o same_o animal_n be_v equal_o strong_a and_o exercise_v a_o equal_a motive_n force_n in_o the_o same_o time_n in_o the_o state_n of_o health_n and_o because_o equal_a bulk_n of_o two_o muscle_n contain_v equal_a multitude_n of_o the_o least_o fibres_fw-fr it_o follow_v that_o if_o we_o have_v foreknow_v the_o total_a motive_n power_n of_o one_o of_o the_o two_o equal_a muscle_n we_o shall_v be_v able_a thence_o to_o conjecture_v what_o be_v the_o total_a power_n motive_n also_o of_o the_o other_o therefore_o the_o fleshy_a bulk_n of_o the_o heart_n be_v of_o almost_o equal_a magnitude_n to_o the_o bulk_n of_o one_o of_o the_o temporal_a muscle_n and_o of_o one_o of_o the_o masseter_n and_o borellus_n have_v demonstrate_v to_o we_o the_o total_a motive_n force_v of_o those_o two_o muscle_n we_o may_v probable_o infer_v that_o the_o motive_n force_n of_o the_o heart_n be_v equal_a to_o that_o which_o those_o two_o muscle_n shut_v the_o mandible_a exercise_n now_o because_o no_o entire_a fiber_n of_o these_o two_o muscle_n be_v less_o than_o two_o inch_n long_a take_v all_o the_o fibres_fw-fr one_o with_o another_o that_o the_o excess_n of_o the_o long_a may_v compensate_a the_o defect_n of_o the_o short_a and_o because_o in_o a_o inch_n space_n of_o every_o single_a fiber_n we_o may_v imagine_v more_o than_o twenty_o little_a machine_n or_o rhomboid_a pore_n contain_v like_o the_o link_n of_o a_o chain_n in_o a_o watch_n or_o the_o mesh_n of_o a_o net_n in_o a_o row_n one_o above_o another_o let_v we_o notwithstanding_o suppose_v no_o more_o than_o ten_o small_a fibre_n to_o be_v contain_v in_o that_o space_n therefore_o in_o the_o length_n of_o every_o one_o of_o the_o fibre_n that_o compose_v the_o say_v two_o muscle_n there_o will_v be_v contain_v more_o than_o twenty_o of_o those_o most_o minute_n machine_n and_o since_o the_o weight_n of_o 150_o pound_n may_v be_v suspend_v by_o one_o single_a stratum_n or_o layer_n of_o these_o small_a machine_n of_o the_o same_o muscle_n therefore_o that_o we_o may_v have_v the_o whole_a force_n that_o nature_n exercise_v in_o those_o muscle_n the_o force_n of_o that_o one_o layer_n viz._n that_o which_o be_v able_a to_o sustain_v 150_o pound_n aught_o to_o be_v twenty_o time_n multiply_v wherefore_o the_o whole_a force_n that_o nature_n exercise_n to_o dilate_v all_o the_o rhomboid_a mesh_n or_o pore_n of_o the_o say_v two_o muscle_n when_o they_o act_v be_v great_a than_o the_o force_n of_o 3000_o pound_n weight_n and_o will_v if_o apply_v to_o the_o opposite_a end_n of_o the_o beam_n of_o a_o balance_n preponderate_a if_o then_o every_o most_o minute_n fiber_n of_o the_o heart_n exercise_v in_o the_o systole_n of_o it_o a_o force_n equal_a to_o that_o which_o every_o 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quod_fw-la erat_fw-la demonstrandum_fw-la and_o thus_o have_v i_o give_v you_o a_o summary_n of_o what_o borellus_n have_v from_o a_o long_a chain_n of_o most_o ingeniose_fw-la proposition_n and_o theorem_n in_o fine_a infer_v i_o come_v therefore_o to_o the._n second_o and_o last_o considerable_a propose_v to_o be_v inquire_v viz._n the_o efficient_a cause_n of_o this_o so_o wonderful_a motive_n force_v of_o the_o heart_n these_o seem_v to_o be_v no_o more_o than_o two_o of_o which_o one_o be_v immediate_a the_o other_o mediate_v as_o to_o the_o the_o former_a viz._n the_o immediate_a cause_n of_o the_o heart_n motive_n power_n we_o be_v not_o to_o expect_v to_o learn_v either_o what_o it_o be_v or_o whence_o it_o proceed_v from_o the_o doctrine_n of_o the_o ancient_n for_o they_o have_v observe_v that_o the_o heart_n be_v not_o as_o all_o the_o other_o muscle_n of_o the_o body_n be_v move_v ad_fw-la arbitrium_fw-la voluntatis_fw-la at_o the_o command_n of_o the_o will_n not_o only_o name_v the_o motion_n of_o those_o voluntary_a and_o the_o motion_n of_o this_o natural_a as_o they_o have_v good_a reason_n to_o do_v but_o also_o conceive_v and_o teach_v the_o cause_n of_o the_o motion_n of_o the_o heart_n to_o be_v divers_a from_o the_o cause_n of_o the_o motion_n of_o the_o rest_n of_o the_o muscle_n and_o according_o constitute_v and_o assign_v to_o the_o heart_n a_o certain_a blind_a and_o unintelligible_a pulsifick_a faculty_n whereto_o alone_o they_o ascribe_v as_o well_o the_o diastole_n as_o the_o systole_n thereof_o which_o they_o have_v no_o just_a reason_n to_o do_v to_o evince_v this_o their_o palpable_a error_n i_o will_v assert_v this_o proposition_n that_o the_o immediate_a motive_n cause_n of_o the_o heart_n be_v the_o very_a same_o with_o that_o by_o which_o the_o muscle_n of_o the_o limb_n be_v move_v voluntary_o first_o it_o be_v most_o evident_a to_o sense_n that_o
little_a canales_n within_o must_v therefore_o be_v full_a of_o small_a asperity_n it_o be_v necessary_a that_o the_o succus_fw-la nervosus_fw-la who_o consistence_n be_v not_o much_o thin_a than_o the_o white_a of_o a_o egg_n well_o beat_v shall_v pass_v through_o they_o with_o a_o slow_a and_o interrupt_a course_n and_o at_o length_n fall_v out_o of_o their_o low_a end_n in_o drop_n with_o equal_a pause_n between_o the_o drop_n where_o we_o find_v a_o parility_n of_o cause_n we_o may_v right_o expect_v a_o similitude_n of_o effect_n here_o i_o see_v two_o formidable_a difficulty_n stand_v like_o romantic_a giant_n in_o my_o way_n to_o deter_v i_o from_o proceed_v and_o i_o can_v without_o shame_n and_o infamy_n decline_v to_o encounter_v they_o one_o be_v that_o after_o the_o cardiac_n nerve_n be_v cut_v off_o and_o the_o heart_n itself_o take_v out_o of_o the_o body_n the_o pulsation_n of_o it_o continue_v for_o some_o time_n to_o remove_v this_o therefore_o i_o say_v that_o the_o cavity_n of_o the_o nerve_n annex_v to_o the_o heart_n may_v remain_v still_o full_a of_o and_o turgid_a with_o the_o roscid_n succus_fw-la nervosus_fw-la which_o be_v hinder_v from_o regress_n by_o their_o spontaneous_a contraction_n towards_o the_o heart_n and_o keep_v in_o a_o state_n of_o fluxility_n by_o the_o yet_o last_a warmth_n of_o the_o heart_n may_v for_o some_o time_n be_v instill_v into_o the_o fibre_n of_o it_o and_o by_o swell_v of_o they_o cause_n they_o to_o constringe_v the_o ventricles_n as_o before_o then_o the_o heart_n be_v irritate_v by_o the_o prick_n of_o a_o needle_n or_o some_o sharp_a and_o pungent_a liquor_n may_v be_v able_a by_o its_o peristaltic_a constriction_n to_o squeeze_v out_o the_o few_o remain_a drop_n of_o the_o roscid_a liquor_n which_o be_v do_v the_o pulsation_n cease_v for_o ever_o to_o the_o blood_n this_o effect_n ought_v not_o to_o be_v ascribe_v for_o after_o all_o relic_n of_o it_o have_v be_v with_o warm_a water_n and_o a_o syringe_n wash_v out_o of_o the_o ventricles_n and_o squeeze_v out_o of_o the_o vessel_n the_o pulsation_n notwithstanding_o will_v continue_v for_o sometime_o nor_o can_v it_o be_v with_o more_o reason_n ascribe_v to_o convulsion_n of_o the_o heart_n because_o all_o convulsion_n be_v disorderly_a and_o unequal_a both_o in_o the_o time_n of_o their_o gird_n and_o in_o those_o of_o their_o intermission_n whereas_o in_o this_o case_n the_o pulsation_n be_v regular_a and_o isochronical_a with_o equal_a pause_n nor_o to_o the_o heat_v communicate_v by_o the_o blood_n to_o the_o heart_n before_o it_o be_v exsect_v and_o not_o yet_o quite_o extinct_a because_o that_o borrow_a heat_n soon_o vanish_v and_o no_o external_a heat_n will_v revive_v the_o languish_a pulsation_n after_o all_o the_o roscid_a juice_n have_v be_v express_v out_o of_o the_o end_n of_o the_o nerve_n leave_v in_o the_o heart_n nothing_o then_o remain_v to_o solve_v this_o phaenomenon_n but_o the_o instillation_n of_o a_o few_o drop_n of_o our_o roscid_a liquor_n into_o the_o fibre_n of_o the_o heart_n to_o swell_v they_o and_o so_o urge_v they_o to_o constriction_n of_o the_o ventricles_n the_o other_o difficulty_n be_v this_o why_o be_v there_o not_o a_o pulsation_n after_o the_o same_o manner_n also_o in_o all_o the_o muscle_n of_o the_o limb_n since_o their_o fibre_n be_v of_o the_o same_o nature_n in_o all_o thing_n their_o disposition_n and_o direction_n only_o except_v since_o the_o orifice_n of_o the_o nerve_n pertain_v to_o they_o be_v in_o the_o brain_n as_o open_a to_o admit_v and_o imbibe_n the_o succus_fw-la nervosus_fw-la there_o elaborate_a and_o provide_v for_o they_o and_o since_o the_o same_o nerve_n be_v equal_o spungy_a and_o permeable_a in_o their_o constitution_n and_o so_o apt_a to_o transfer_v that_o liquor_n as_o the_o orifice_n of_o the_o cardiac_n nerve_n be_v to_o receive_v or_o their_o canales_n to_o transfer_v it_o if_o the_o whole_a apparatus_n be_v the_o same_o on_o both_o part_n whence_o come_v it_o that_o the_o same_o effect_n be_v not_o produce_v in_o both_o at_o this_o goliath_n i_o have_v in_o my_o scrip_n three_o pebble_n to_o throw_v and_o though_o my_o arm_n be_v weak_a i_o will_v not_o despair_v of_o hit_v he_o in_o the_o forehead_n first_o therefore_o i_o say_v that_o it_o be_v not_o yet_o certain_o know_v to_o any_o mortal_a man_n by_o what_o mediate_a cause_n the_o muscle_n of_o the_o limb_n be_v move_v at_o the_o command_n of_o the_o will_n whether_o by_o simple_a contraction_n of_o the_o original_n of_o the_o nerve_n insert_v into_o they_o or_o by_o the_o immission_n of_o the_o succus_fw-la nervosus_fw-la more_o copiose_o and_o swift_o at_o the_o time_n of_o their_o be_v put_v into_o action_n though_o the_o mechanism_n of_o their_o fibre_n make_v it_o more_o probable_a that_o they_o be_v move_v by_o immission_n of_o some_o liquor_n from_o the_o brain_n by_o which_o the_o rhomboid_a mesh_n or_o pore_n of_o their_o fibre_n be_v all_o at_o the_o same_o time_n swell_v and_o dilate_v a_o contraction_n of_o the_o whole_a muscle_n must_v in_o the_o same_o moment_n be_v effect_v and_o therefore_o i_o prefer_v this_o opinion_n to_o the_o former_a and_o have_v follow_v it_o in_o many_o place_n of_o this_o rude_a discourse_n but_o yet_o this_o opinion_n have_v not_o lead_v i_o to_o a_o discovery_n of_o the_o cause_n of_o the_o difference_n this_o present_a difficulty_n compel_v i_o to_o hunt_v after_o shall_v i_o imagine_v valve_n affix_v by_o nature_n to_o the_o orifice_n of_o the_o nerve_n of_o the_o muscle_n as_o mons_fw-la des_n cartes_n do_v in_o the_o body_n of_o they_o though_o such_o a_o artifice_n be_v not_o impossible_a yet_o beside_o that_o no_o such_o valve_n have_v hitherto_o be_v find_v in_o the_o brain_n i_o shall_v still_o be_v to_o seek_v for_o a_o cause_n to_o open_v and_o shut_v they_o ad_fw-la arbitrium_fw-la voluntatis_fw-la and_o so_o shall_v be_v put_v to_o a_o stand_n in_o my_o disquisition_n which_o to_o avoid_v some_o other_o organical_a contrivement_n such_o as_o may_v be_v not_o only_o possible_a but_o probable_a also_o and_o facile_a and_o fit_a to_o untie_v this_o gordian_a knot_n must_v be_v excogitated_a let_v it_o then_o be_v suppose_v that_o in_o the_o brain_n the_o orifice_n of_o the_o nerve_n thence_o elonge_v to_o the_o muscle_n of_o the_o limb_n and_o their_o canales_n be_v in_o such_o a_o peculiar_a manner_n form_v as_o at_o no_o time_n to_o take_v in_o and_o convey_v into_o the_o muscle_n more_o of_o the_o roscid_a liquor_n than_o what_o be_v sufficient_a to_o nourish_v they_o and_o recruit_v their_o vigour_n unless_o when_o at_o the_o command_n of_o the_o will_n under_o who_o jurisdiction_n they_o proper_o be_v the_o nerve_n be_v twitch_v up_o or_o convel_v at_o their_o original_n both_o their_o orifice_n be_v dilate_v to_o receive_v and_o their_o canales_n render_v more_o pervious_a to_o transmit_v in_o a_o moment_n into_o the_o fibre_n of_o the_o muscle_n to_o be_v use_v a_o great_a portion_n of_o the_o same_o invigorate_n liquor_n viz._n so_o much_o as_o be_v requisite_a to_o swell_v they_o up_o by_o replenish_n their_o pore_n and_o force_v they_o to_o contraction_n which_o be_v the_o common_a action_n of_o all_o muscle_n on_o the_o other_o part_n let_v it_o be_v suppose_v that_o in_o the_o brain_n nature_n have_v frame_v the_o original_n of_o the_o cardiac_n nerve_n by_o a_o different_a artifice_n namely_o such_o as_o that_o not_o only_o their_o orifice_n may_v always_o be_v open_a to_o imbibe_n but_o also_o their_o canales_n so_o easy_o pervious_a to_o transmit_v the_o roscid_a liquor_n as_o that_o without_o any_o vellication_n without_o any_o convulsive_a motion_n the_o same_o liquor_n may_v mere_o by_o the_o plenitude_n of_o the_o canales_n themselves_o be_v effuse_v guttulatim_fw-la into_o the_o fibre_n of_o the_o heart_n to_o cause_v the_o alternate_a constriction_n or_o pulsation_n of_o it_o and_o it_o be_v the_o more_o lawful_a for_o i_o to_o suppose_v this_o difference_n of_o structure_n in_o nerve_n ordain_v for_o different_a use_n because_o it_o be_v above_o all_o doubt_n that_o the_o optic_a nerve_n have_v a_o peculiar_a fabric_n and_o contexture_n wherein_o they_o differ_v from_o the_o auditory_a and_o all_o other_o nerve_n inservient_fw-la to_o the_o rest_n of_o the_o external_a sense_n and_o that_o the_o organ_n of_o every_o sense_n have_v its_o nerve_n of_o a_o peculiar_a constitution_n accommodate_v to_o the_o nature_n of_o its_o proper_a object_n though_o those_o difference_n consist_v in_o such_o minute_n and_o subtle_a artifices_fw-la as_o have_v hitherto_o elude_v our_o most_o curiose_fw-la research_v though_o assist_v by_o the_o best_a sort_n of_o microscope_n why_o then_o may_v it_o not_o be_v think_v that_o nature_n have_v give_v to_o the_o cardiac_n nerve_n also_o a_o constitution_n divers_a from_o that_o of_o all_o
teach_v we_o that_o some_o influence_n whatever_o it_o be_v derive_v from_o the_o brain_n to_o the_o heart_n be_v absolute_o necessary_a to_o the_o incitement_n and_o perpetuation_n of_o the_o motion_n of_o the_o heart_n for_o the_o brain_n be_v in_o a_o great_a part_n perfect_v before_o the_o heart_n though_o those_o two_o member_n ob_fw-la communem_fw-la officii_fw-la necessitudinem_fw-la be_v almost_o congenite_fw-la and_o i_o have_v good_a cause_n to_o believe_v that_o the_o exordium_n of_o the_o brain_n be_v that_o colliquamentum_fw-la which_o be_v first_o see_v in_o a_o egg_n after_o the_o first_o day_n incubation_n of_o the_o hen_n and_o which_o by_o the_o same_o warmth_n continue_v do_v in_o a_o short_a time_n concrete_a and_o be_v condense_v into_o a_o thick_a substance_n that_o be_v soon_o invest_v as_o every_o viscid_a humour_n be_v wont_a to_o be_v with_o a_o thin_a film_n or_o membrane_n and_o shoot_v forth_o from_o itself_o little_a nerve_n as_o branch_n every_o way_n from_o the_o observation_n of_o which_o that_o incomparable_a man_n sir_n george_n ent_n doubt_v not_o public_o to_o declare_v himself_o to_o be_v of_o this_o opinion_n 7._o that_o not_o the_o heart_n but_o the_o brain_n be_v the_o fountain_n of_o life_n his_o word_n be_v these_o cor_fw-la enim_fw-la uti_fw-la arbitror_fw-la non_fw-la est_fw-la fons_fw-la aquavitae_fw-la qui_fw-la cerebro_fw-la peculiaris_fw-la est_fw-la sed_fw-la rivulus_fw-la duntaâ—at_fw-la accessorius_fw-la which_o yet_o be_v no_o new_a opinion_n but_o ascribe_v by_o galen_n to_o erasistratus_n 3._o who_o say_v omnium_n quae_fw-la in_o corpore_fw-la sunt_fw-la principium_fw-la esse_fw-la cerebrum_fw-la apparet_fw-la and_o assert_v by_o hippon_n who_o censorinus_n introduce_v right_o teach_v caput_fw-la primò_fw-la fieri_fw-la now_o what_o can_v we_o with_o equal_a probability_n conceive_v to_o be_v the_o reason_n why_o nature_n finish_v the_o brain_n before_o the_o heart_n as_o this_o i_o have_v here_o give_v viz._n because_o the_o heart_n even_o from_o the_o beginning_n have_v need_n of_o some_o influence_n to_o be_v transmit_v from_o the_o brain_n to_o it_o for_o the_o incitement_n and_o continuation_n of_o its_o motion_n as_o well_o as_o for_o the_o nutrition_n of_o its_o substance_n the_o latter_a of_o which_o benefit_n be_v common_a to_o the_o heart_n with_o all_o other_o part_n of_o the_o body_n second_o it_o be_v high_o probable_a that_o the_o brain_n be_v not_o only_o the_o laboratory_n but_o also_o the_o common_a promptuary_n of_o the_o true_a succus_fw-la nutritius_fw-la and_o that_o the_o nerve_n be_v the_o cane_n or_o filtre_n through_o who_o long_a and_o narrow_a pore_n the_o same_o roscid_a nutritive_a liquor_n be_v gentle_o distribute_v to_o all_o part_n for_o their_o nourishment_n both_o which_o proposition_n have_v be_v former_o with_o many_o considerable_a argument_n draw_v as_o well_o from_o experiment_n anatomical_a as_o from_o reason_n assert_v by_o sir_n george_n ent_n dr._n glisson_n and_o if_o it_o be_v lawful_a for_o i_o to_o put_v myself_o into_o the_o same_o period_n with_o such_o excellent_a man_n myself_o this_o therefore_o be_v suppose_v it_o be_v not_o unreasonable_a to_o think_v that_o this_o roscid_n balsamic_a and_o spirituose_fw-la liquor_n by_o many_o call_v succus_fw-la nervosus_fw-la be_v for_o the_o most_o part_n in_o sufficient_a plenty_n in_o the_o brain_n do_v at_o all_o time_n touch_v and_o soak_v into_o the_o open_a pore_n of_o all_o the_o nerve_n thence_o elonge_v but_o more_o copious_o into_o the_o nerve_n that_o extend_v themselves_o into_o the_o fibrose_a substance_n of_o the_o heart_n because_o the_o heart_n be_v furnish_v with_o many_o more_o and_o large_a nerve_n than_o any_o other_o muscle_n of_o the_o whole_a body_n and_o because_o the_o extreme_o narrow_a cavity_n of_o the_o nerve_n be_v full_a of_o a_o spungy_a medullary_n substance_n and_o continual_o wet_a with_o the_o same_o roscid_a liquor_n creep_v through_o they_o therefore_o the_o liquor_n can_v flow_v out_o of_o the_o low_a end_n of_o they_o into_o the_o fibre_n of_o the_o heart_n otherwise_o than_o guttatim_fw-la drop_v after_o drop_n as_o all_o liquor_n chief_o such_o as_o have_v any_o thing_n of_o viscidity_n slow_o creep_v along_o the_o thread_n of_o filtre_n and_o when_o they_o at_o length_n arrive_v at_o the_o end_n fall_v down_o in_o equal_a drop_n with_o equal_a pause_n betwixt_o the_o precedent_n and_o the_o succeed_v drop_n far_o because_o the_o distillation_n of_o each_o drop_n be_v almost_o momentaneous_a not_o persevere_v thence_o it_o seem_v to_o come_v that_o the_o constriction_n of_o the_o heart_n be_v perform_v and_o finish_v in_o a_o moment_n and_o a_o pause_n succeed_v in_o the_o next_o moment_n till_o a_o second_o drop_n come_v to_o cause_v a_o second_o constriction_n and_o so_o forward_o and_o since_o in_o the_o brain_n or_o fountain_n of_o this_o roscid_a liquor_n there_o be_v always_o plenty_n to_o maintain_v a_o perpetual_a succession_n of_o drop_n and_o the_o liquor_n itself_o be_v in_o the_o state_n of_o health_n always_o of_o the_o same_o temper_n and_o consistence_n and_o the_o narrow_a canales_n in_o the_o nerve_n always_o equal_o retard_v its_o descent_n and_o efflux_n therefore_o it_o seem_v necessary_a that_o the_o time_n of_o quiet_a or_o the_o pause_v intervenient_a betwixt_o the_o drop_n shall_v be_v equal_a so_o long_o as_o the_o liquor_n retain_v the_o same_o degree_n of_o fluxility_n or_o be_v not_o hinder_v by_o great_a violence_n but_o if_o it_o happen_v that_o the_o liquor_n be_v become_v either_o more_o thin_a and_o fluxible_a than_o be_v fit_a as_o common_o it_o do_v upon_o debauch_n with_o wine_n or_o other_o strong_a drink_n or_o saline_n acrimonious_a acid_n or_o of_o any_o other_o vicious_a and_o irritate_v quality_n as_o often_o it_o be_v vitiate_a in_o many_o malady_n chief_o in_o scorbuto_n inveterato_fw-la or_o fall_v into_o a_o fermentation_n which_o i_o have_v reason_n to_o conjecture_v it_o always_o do_v in_o fever_n and_o more_o eminent_o in_o the_o small_a pox_n the_o matter_n of_o which_o seem_v to_o be_v not_o the_o blood_n but_o the_o succus_fw-la nutritius_fw-la in_o a_o peculiar_a manner_n corrupt_v and_o critical_o transmit_v from_o the_o brain_n through_o the_o nerve_n into_o the_o habit_n of_o the_o body_n or_o be_v agitate_a by_o any_o swift_a motion_n as_o in_o the_o more_o violent_a passion_n of_o the_o mind_n and_o chief_o in_o anger_n it_o be_v in_o all_o these_o case_n the_o motion_n and_o distil_v of_o it_o into_o the_o fibre_n of_o the_o heart_n must_v be_v accelerate_a proportionate_o and_o consequent_o the_o systole_n of_o the_o heart_n will_v be_v more_o frequent_o repete_v and_o the_o pause_v intercedent_a betwixt_o they_o will_v be_v as_o those_o intervenient_a betwixt_o the_o drop_n short_a and_o here_o a_o fair_a occasion_n offer_v itself_o to_o i_o of_o expatiate_v into_o the_o various_a and_o numerose_n difference_n of_o pulse_n of_o the_o heart_n and_o endeavour_v to_o solve_v they_o rational_o by_o this_o hypothesis_n which_o alone_o be_v capable_a to_o do_v it_o but_o the_o shortness_n of_o the_o time_n appoint_v for_o my_o sit_v in_o this_o place_n forbid_v i_o to_o make_v use_n of_o the_o occasion_n of_o this_o stillicidium_fw-la or_o guttulation_n of_o the_o succus_fw-la nervosus_fw-la out_o of_o the_o end_n of_o the_o cardiac_n nerve_n we_o have_v various_a familiar_a example_n we_o see_v that_o sponge_n filtre_n and_o even_o glass_n tube_v of_o very_o small_a bore_n though_o they_o be_v continual_o replete_a with_o water_n or_o any_o other_o liquor_n yet_o the_o liquor_n do_v not_o flow_v out_o of_o their_o low_a end_n or_o orifice_n in_o a_o continue_a course_n as_o water_n gush_v out_o of_o a_o fountain_n or_o out_o of_o the_o cock_n of_o a_o cistern_n but_o by_o drop_n with_o aequitemporaneous_a stop_n or_o pause_n betwixt_o the_o drop_n the_o true_a cause_n of_o which_o effect_n seem_v to_o be_v this_o the_o great_a narrowness_n of_o the_o canales_n which_o impede_v the_o free_a permeation_n of_o the_o liquor_n the_o little_a particle_n or_o moleculae_fw-la of_o the_o liquor_n be_v not_o exact_o smooth_a but_o villose_o and_o viscose_v and_o therefore_o they_o be_v force_v to_o creep_v along_o with_o a_o slow_a pace_n through_o the_o cavity_n of_o the_o tube_n who_o superfice_n within_o be_v equal_o full_a of_o little_a asperity_n too_o so_o that_o they_o must_v as_o they_o pass_v along_o be_v put_v into_o a_o vertiginose_a motion_n and_o interrupt_v their_o course_n and_o consequent_o fall_v out_o of_o the_o low_a end_n of_o the_o sponge_n filtre_n or_o tube_n guttatim_fw-la now_o since_o the_o nerve_n be_v like_o indian_a cane_n compose_v of_o filament_n run_v their_o whole_a length_n in_o direct_a line_n a_o medullary_n and_o spungy_a substance_n and_o many_o little_a interstice_n interjacent_a betwixt_o the_o filament_n with_o a_o thin_a coat_n invest_v they_o and_o since_o the_o superfice_n of_o their_o
see_v that_o the_o liquor_n find_v in_o the_o pericardium_n be_v easy_o capable_a of_o coagulation_n either_o by_o heat_n or_o cold_a so_o as_o to_o become_v like_o jelly_n of_o hartshorn_n or_o the_o white_a of_o a_o egg_n harden_v by_o boil_v as_o the_o serum_fw-la of_o the_o blood_n will_v do_v and_o observe_v the_o various_a little_a gland_n seat_v about_o the_o basis_n of_o the_o heart_n for_o which_o i_o can_v find_v no_o other_o equal_o probable_a use_n as_o to_o instil_v the_o serum_fw-la into_o the_o pericardium_n to_o facilitate_v the_o motion_n of_o the_o heart_n which_o most_o certain_o that_o liquor_n do_v as_o the_o humour_n instill_v out_o of_o the_o glandulae_fw-la lacrymale_n upon_o the_o outside_n of_o the_o eye_n serve_v to_o moisten_v and_o make_v they_o more_o easy_o movable_a every_o way_n when_o i_o have_v i_o say_v observe_v and_o consider_v these_o thing_n i_o reject_v that_o thought_n and_o embrace_v this_o of_o the_o absorption_n of_o the_o relic_n of_o the_o succus_fw-la nervosus_fw-la by_o the_o vein_n of_o the_o heart_n the_o second_o be_v that_o the_o diastole_n of_o the_o heart_n be_v cause_v partly_o by_o the_o relaxation_n of_o the_o fibre_n of_o it_o spontaneous_o restore_v themselves_o to_o their_o natural_a posture_n and_o length_n as_o all_o other_o tensile_n body_n be_v wont_a to_o do_v after_o they_o have_v be_v distend_v partly_o by_o the_o force_n of_o the_o blood_n rush_v out_o of_o the_o ear_n into_o the_o ventricles_n of_o the_o heart_n and_o replenish_n they_o wherefore_o the_o wisdom_n of_o nature_n be_v admirable_a also_o in_o this_o that_o she_o ordain_v these_o two_o cause_n of_o the_o diastole_n viz._n the_o relaxation_n of_o the_o fibre_n and_o the_o influx_n of_o the_o blood_n into_o the_o ventricles_n to_o be_v exact_o coincident_a that_o with_o unite_a force_n they_o may_v cooperate_v more_o efficacious_o whence_o it_o appear_v that_o in_o the_o diastole_n the_o heart_n be_v not_o whole_o passive_a as_o all_o anatomist_n hitherto_o have_v believe_v it_o to_o be_v for_o unless_o the_o fibres_n do_v restore_v themselves_o to_o their_o former_a longitude_n which_o be_v a_o natural_a action_n at_o the_o same_o time_n the_o influx_n of_o the_o blood_n happen_v certain_o there_o can_v be_v no_o room_n to_o receive_v the_o blood_n because_o the_o inside_n of_o the_o ventricles_n will_v continue_v to_o touch_v each_o the_o other_o and_o so_o there_o can_v be_v no_o diastole_n the_o three_o and_o last_o be_v that_o it_o appear_v from_o the_o whole_a series_n of_o this_o discourse_n that_o the_o pulsation_n or_o constriction_n of_o the_o heart_n have_v its_o force_n from_o that_o mechanic_n power_n which_o be_v call_v the_o wedge_n and_o that_o the_o blood_n be_v express_v out_o of_o the_o heart_n by_o virtue_n of_o another_o mechanic_n power_n which_o be_v name_v the_o praelum_fw-la or_o press_n and_o consequent_o that_o the_o heart_n itself_o be_v as_o all_o automata_n be_v move_v not_o by_o spirit_n nor_o by_o a_o pulsifick_a faculty_n nor_o by_o rarefaction_n of_o the_o blood_n nor_o ebullition_n or_o fermentation_n of_o the_o blood_n nor_o by_o explosion_n of_o saline_n and_o acid_n spirituose_fw-la liquor_n but_o by_o mechanic_n necessity_n which_o from_o the_o beginning_n i_o hope_v i_o shall_v be_v able_a fair_o to_o prove_v if_o the_o success_n of_o my_o endeavour_n have_v not_o be_v answerable_a to_o that_o hope_n i_o will_v not_o go_v about_o to_o extenuate_v the_o blame_n of_o my_o faileur_n by_o cite_v example_n of_o much_o great_a wit_n which_o have_v before_o i_o in_o vain_a attempt_v to_o reveal_v the_o same_o secret_a of_o nature_n but_o consolate_v myself_o with_o this_o that_o my_o judge_n be_v man_n no_o less_o belove_v for_o their_o exemplary_a candour_n and_o humanity_n than_o honour_v for_o their_o excellency_n in_o all_o kind_n of_o learning_n and_o who_o need_v not_o be_v put_v in_o mind_n that_o truth_n be_v a_o tree_n who_o root_n be_v in_o heaven_n and_o of_o which_o even_o the_o wise_a of_o we_o dim-sighted_a mortal_n here_o upon_o earth_n see_v nothing_o but_o the_o shadow_n of_o its_o branch_n i_o will_v therefore_o conclude_v this_o inelaborate_a disquisition_n with_o that_o memorable_a say_n of_o the_o prince_n of_o roman_a orator_n consolation_n de_n his_o statuat_fw-la unusquisque_fw-la ut_fw-la libet_fw-la quid_fw-la autem_fw-la verius_fw-la sit_fw-la deus_fw-la ipse_fw-la viderit_fw-la hominem_fw-la quidem_fw-la scire_fw-la arbitror_fw-la neminem_fw-la ¶_o ⸫_o my_o lecture_n such_o as_o they_o be_v much_o honour_a auditor_n you_o have_v with_o oblige_a patience_n hear_v be_v please_v i_o beseech_v you_o to_o hear_v also_o before_o you_o rise_v a_o word_n which_o i_o have_v to_o speak_v in_o my_o own_o defence_n be_v it_o not_o indecent_a to_o compare_v small_a thing_n with_o great_a i_o shall_v venture_v perhaps_o to_o advertise_v you_o that_o the_o reason_n which_o induce_v i_o to_o attempt_v a_o reformation_n of_o the_o borellian_a hypothesis_n of_o the_o motion_n of_o the_o heart_n which_o doctor_n harvey_n himself_o call_v the_o sun_n of_o the_o microcosm_n sanguine_a seem_v to_o have_v some_o kind_n of_o analogy_n to_o those_o which_o move_v the_o prince_n of_o astronomer_n tycho_n brahe_n to_o dislike_v the_o ptolemaic_a system_n of_o the_o macrocosm_n or_o great_a world_n and_o to_o excogitate_v a_o new_a one_o of_o more_o probability_n and_o neatness_n for_o as_o tycho_n animadvert_v that_o the_o celestial_a orb_n have_v be_v by_o ptolemy_n distribute_v unhansom_o that_o so_o many_o and_o so_o great_a epicycle_n be_v in_o vain_a imagine_v to_o explicate_v the_o retrogradation_n of_o the_o planet_n and_o their_o various_a respect_n to_o the_o sun_n and_o that_o the_o equality_n of_o the_o circular_a motion_n be_v measure_v not_o from_o the_o centre_n of_o its_o proper_a circle_n as_o it_o ought_v but_o from_o the_o centre_n of_o another_o eccentric_a circle_n against_o the_o first_o principle_n of_o nature_n and_o art_n invent_v a_o new_a system_fw-la exempt_a from_o all_o these_o incommodity_n which_o be_v in_o truth_n the_o copernican_n invert_v so_o i_o conceive_v that_o in_o the_o borellian_a hypothesis_n and_o explosion_n of_o i_o know_v not_o what_o saline_n and_o acid_n material_n in_o the_o heart_n be_v not_o only_o in_o itself_o extreme_o improbable_a and_o incongruous_a to_o the_o wisdom_n of_o nature_n which_o always_o constitute_v certain_a and_o regular_a cause_n to_o produce_v certain_a and_o regular_a effect_n but_o also_o unnecessary_o suppose_v to_o solve_v the_o phaenomenon_n of_o the_o heart_n pulsation_n set_v my_o dull_a brain_n on_o work_n to_o reform_v it_o and_o soon_o invent_v another_o that_o seem_v both_o free_a from_o those_o inconvenience_n and_o more_o agreeable_a to_o the_o organical_a structure_n of_o the_o heart_n to_o which_o above_o all_o thing_n it_o be_v requisite_a i_o shall_v endeavour_v to_o adjust_a it_o this_o i_o think_v myself_o oblige_v to_o signify_v lest_o any_o here_o shall_v believe_v either_o that_o i_o have_v usurp_v to_o myself_o this_o whole_a system_n of_o the_o motion_n of_o the_o heart_n from_o that_o most_o excellent_a mathematician_n alphonsus_n borellus_n who_o memory_n i_o high_o honour_n or_o that_o i_o lay_v claim_n to_o more_o than_o a_o candid_a attempt_n to_o reform_v it_o ¶_o ⸫_o epilogus_fw-la praelectionum_fw-la quidem_fw-la vela_fw-la jam_fw-la tandem_fw-la contraxi_fw-la nondum_fw-la tamen_fw-la dissolutam_fw-la video_fw-la concionem_fw-la resistamus_fw-la igitur_fw-la hîc_fw-la parumper_fw-la auditores_fw-la ornatissimâ—_n si_fw-la vobis_fw-la ita_fw-la videatur_fw-la &_o ad_fw-la stupendam_fw-la illam_fw-la cujus_fw-la rationem_fw-la mechanicam_fw-la hactenus_fw-la tam_fw-la anxiè_fw-la inquisivimus_fw-la cordis_n fabricam_fw-la seriò_fw-la respiciamus_fw-la ind_n enim_fw-la etiamsi_fw-la alia_fw-la omne_fw-la in_o universitate_fw-la rerum_fw-la deessent_fw-la divinae_fw-la architecturae_fw-la documenta_fw-la cuivis_fw-la hominum_fw-la pronum_fw-la est_fw-la infer_v &_o quam_fw-la sit_fw-la immensa_fw-la illius_fw-la caeterorumque_fw-la omnium_fw-la in_o hoc_fw-la mundo_fw-la adspect_n abilium_fw-la conditoris_fw-la solertia_fw-la quámque_fw-la parum_fw-la ab_fw-la immedicabili_fw-la cum_fw-la animi_fw-la tum_fw-la mentis_fw-la stupiditate_fw-la olim_fw-la abfuerit_fw-la epicurus_n qui_fw-la animalia_fw-la casu_fw-la quodam_fw-la in_fw-la prima_fw-la rerum_fw-la procreatione_fw-la genita_fw-la fuisse_fw-la vecorditer_fw-la censuit_fw-la &_o opinatus_fw-la est_fw-la consequenter_fw-la totam_fw-la in_o iis_fw-la membrorum_fw-la varietatem_fw-la dearticulationemque_fw-la non_fw-la aliunde_fw-la quam_fw-la ex_fw-la atomorum_fw-la fortè_fw-la fortuna_fw-la post_fw-la infinitos_fw-la inter_fw-la se_fw-la in_o spatio_fw-la infinito_fw-la vortices_fw-la ita_fw-la concurrentium_fw-la atque_fw-la commistarum_fw-la dispositione_n extitisse_fw-la quamobrem_fw-la neque_fw-la ullam_fw-la fuisse_fw-la intelligentis_fw-la naturae_fw-la prudentiam_fw-la quae_fw-la ossa_fw-la cerebrum_fw-la cor_fw-la nervos_fw-la venas_fw-la quae_fw-la oculos_fw-la manus_fw-la pedes_fw-la viscera_fw-la quae_fw-la cetera_fw-la omne_fw-la conformans_fw-la ad_fw-la fine_n certos_fw-la seu_fw-la functiones_fw-la partibus_fw-la congruas_fw-la respexerit_fw-la sed_fw-la singulas_fw-la part_n ita_fw