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A32714 Three anatomic lectures concerning 1. the motion of the bloud through the veins and arteries, 2. the organic structure of the heart, 3. the efficient causes of the hearts pulsation : read on the 19, 20 and 21 by Walter Charleton ... Charleton, Walter, 1619-1707. 1683 (1683) Wing C3693; ESTC R20046 64,495 126

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of the Muscles of the Guts Stomach Tendons Membranes and the like Fibrose parts naturally resist distraction and have a power of contracting themselves after extension Yea more we see that all Fibres even in their natural posture are somewhat upon the stretch for when they are cut they instantly shorten themselves toward both ends which would not happen if they had been constituted in a middle state betwixt laxity and extension as a Bow unbent is quiet suffering neither contraction nor distraction of its parts Now if all Fibres even in their natural state suffer some degree of stretching certainly when the Arteries are replenisht with bloud their cavity must be dilated and in the dilatation of their cavity their transverse or circular Fibres must suffer much more stretching than they did before And because to this dilatation of the Arteries a constriction immediately succeeds which is not possible to be effected without an abbreviation of the circular Fibres of the Arteries and because that abbreviation or contraction is connatural to the Fibres themselves therefore it is impossible that the Arteries after that violent stretching caused by their repletion and turgency should not exercise by natural necessity that mechanic power they have of contracting themselves by vertue of their circular Fibres girding them inward and equally impossible that the Arteries should so contract themselves without expelling at the same time out of their Orifices the bloud that dilated them Whence it appears beyond dispute that the spontaneous constriction of the distended Arteries is the cause of the expulsion of the bloud out of them into the substance of the parts contrary to their opinion who ascribe this expulsion only to the Systole of the heart ¶ ⸪ The natural method of acquiring Science ye know is to begin from things more known and then to advance to things less known to procede from effects to their causes Seeing therefore that we are now certain that the bloud in Animals is carried by a perpetual circular motion through all parts of the body our next business is to enquire what are the Causes of this admirable motion as well the final as the efficient I begin from the final it being a question worthy our consideration why or to what end Nature all whose counsels and actions are ordained by an infinite wisdom hath instituted this rapid Circulation of the bloud Constant it is even from common experience that whenever the bloud is quiet or ceases from motion whether within or without the body of an Animal the red and grumose part of it soon curdles and is separated from the serose or albumen and so the constitution or contexture of it is dissolved and corrupted whereas on the contrary while the bloud continues in perpetual motion within its vessels in the body of a living Animal so long the ordinate mixture of its elements due temper and vital constitution of it is conserved for mechanical reasons in our ensuing discourse to be explained It seems then that such a mixture of the constituent parts of the bloud upon which the vitality of it doth necessarily depend cannot be otherwise conserved than by a continual agitation and concussion made in the vessels first by the heart with strong force impelling the bloud through the Arteries then that impulsive force languishing by filtration in the spaces intermediate betwixt the Arteries and Veins next in the Veins by the constriction of their circular Fibres by the compression of the Muscles and the Viscera and the inspired air All which compressions would not suffice were not Valves placed commodiously within the Veins by which the motion of the bloud is accelerated and a farther conquassation of it made And here we meet with a fair occasion to reflect upon the mutual Anastomôses of the Capillary Veins and the infrequent distribution of Valves in one and the same Vein for both these contribute also their proportions toward the end now under our disquisition For the texture of the Veins being indeed lax and soft yet such as may by virtue of their circular Fibres be constringed and contracted hence it is that by the bloud regurgitating in those tracts of the Veins that have no Valves by the great quantity and force of its regurgitation or recoiling the lowest part of the Vein is much dilated and on the contrary the highest part is contracted So that the bloud being by this reflux though inobservable agitated and conquassated may revive its due commistion and conserve its vital constitution It appears then the defect of Valves also hath its use Within the cavities of the Arteries as I said before no Valves are placed because the grand force by which the bloud is impell'd through them is more than sufficient to conquassate and commix it by wedging in as it were the more fluid albugineous particles among the red grumose particles that from both sorts comixt per minimas moleculas as they say and yet mutually reluctant the Vital Mication or Oscillatory intestine motion of the bloud may be continued So then here is neither need of nor place for a Fermentation Now from the consideration of these things premised I conclude that the Circulation of the Bloud was instituted for the conservation of its requisite temper and vital constitution Which was to be inquired and which leads us to The admirable effects and benefits arising to the Animal Oeconomy from the same Velocity of the Circulation of the Bloud Which being certainly so great that the whole mass of bloud runs its circular race in the twentieth part of an hour or thereabouts even in a sedentary and sedate man as hath by many been demonstrated from the quantity of bloud commonly contein'd in the body from the number of Pulses made in an hour and from the quantity of bloud exprest by every pulse of the heart and we having already seen what advantage redounds to the bloud it self from this velocity our curiosity spurs us on to enquire also what other scopes or ends Nature may probably be conceived to have proposed to herself when she instituted this so rapid motion or what emoluments and benefits from thence redound to the Oeconomy of the whole body Of these the first seems to be this that in every pulsation of the heart a great quantity of bloud is effused and protruded out of the Capillary Arteries into the habit of the parts for their refocillation by influent life of which I have formerly discoursed copiosely in this place For by how much swifter the motion of any liquor or other fluid through a pipe or canale is so much a greater quantity of it is in equal time effused at the Orifice thereof as hath been ingeniously demonstrated by B. Castellus and therefore the bloud is like a full and rapid torrent impelled into the Pores of the flesh and Viscera The second is the energy of the stroke with which the bloud projected by the heart dashes against the same extreme parts which energy is
carry on the resemblance a little farther I soon discovered the disparities to be so many and so great that it was impossible to reconcile them into a just Analogy Whereupon condemning the extravagance of my fancy I soberly concluded that the Heart of an Animal is an Engine never to be imitated by human art and I found my self more inclined to applaud the judgment of that prodigy of Mathematical knowledge Archimedes of Syracuse for never attempting to counterfeit the motions of the heart than to admire his wit shewn in making a Sphear of Glass Athan. Kircher denies that any part of it was Glass but only the out-side that men might discern the wheels and motions within which represented the perfect order and motions of the Celestial Bodies and which Claudian describes in one of his Epigrams Now if we desire clearly to understand this inimitable Excellency of the Machine of the Heart and in what Proprieties of it the same doth chiefly consist we shall be obliged well to consider two things neither of which hath yet been explicated by us and without a due explication of both which all that we have hitherto said concerning the motion of the Heart will be maimed and unsatisfactory These are the Mighty and incredible Motive force of the Heart by which it expresseth the bloud out of the Ventricles and the Efficient Causes of its Motion Things so worthy to be known that I need not deprecate your impatience most Candid and accomplished Auditors if I detain you a few minutes longer while I enquire into them As to the FIRST therefore viz. The admirable Motive force of the Heart Since the round and Conical Figure of the Heart doth not permit us to attempt the measuring of its Motive power by the same way by which the most Learned Alphonsus Borellus hath with singular sagacity measured the forces of very many other Muscles of Mans body namely by weights suspended by them and since therefore in this disquisition we cannot from the effect procede to the knowledge of the cause we are compelled from some other Sign to raise a probable conjecture whence we may investigate the greatness of the effect And this Sign shall be the Similitude and Analogy which the Muscule of the heart seems to hold to other Muscles of the same Animal Let us then with the same excellent Mathematician Borellus in whose footsteps I now again tread suppose that all even the least Fibres or little Machines of the same or divers Muscules in the same Animal are equally strong and exercise an equal motive force in the same time in the state of health And because equal bulks of two Muscles contein equal multitudes of the least Fibres it follows that if we have foreknown the total motive power of one of the two equal Muscles we shall be able thence to conjecture what is the total power motive also of the other Therefore the fleshy bulk of the heart being of almost equal magnitude to the bulks of one of the Temporal muscles and of one of the Masseters and Borellus having demonstrated to us the total motive force of those two muscles we may probably infer that the motive force of the heart is equal to that which those two muscles shutting the mandible exercise Now because no intire Fibre of these two muscles is less than two inches long taking all the Fibres one with another that the excesses of the longer may compensate the defects of the shorter and because in an inches space of every single Fibre we may imagine more than twenty little Machines or Rhomboid Pores contained like the links of a chain in a Watch or the Meshes of a Net in a row one above another let us notwithstanding suppose no more than ten smallest Fibres to be conteined in that space therefore in the length of every one of the Fibres that compose the said two Muscles there will be conteined more than twenty of those most minute Machines And since the weight of 150 pounds may be suspended by one single Stratum or Layer of these small Machines of the same Muscles therefore that we may have the whole force that Nature exerciseth in those Muscles the force of that one Layer viz. that which is able to sustain 150 pounds ought to be twenty times multiplied Wherefore the whole force that Nature exercises to dilate all the Rhomboid meshes or pores of the said two Muscles when they act is greater than the force of 3000 pound weight and would if applied to the opposite end of the beam of a balance preponderate If then every most minute Fibre of the Heart exerciseth in the Systole of it a force equal to that which every Rhomboidal Machine of the Temporal or Masseter muscle makes when they act as most certainly it doth the motive power of all Fibres of the Muscles in the same Animal in the state of health being equal and if the multitude of least Fibres contein'd in those two Muscles be equal to the multitude of most minute Fibres contein'd in the Muscle of the Heart as the visible equality of their magnitudes warrants us to suppose it to be we may thence deduce this conclusion that the force which all the most minute Fibres of the heart when they are swell'd exercise to constringe the Ventricles i. e. when they act all together exceeds the force of 3000 pound weight and would preponderate if it were applied to the contrary end of the beam of a just balance Quod erat demonstrandum And thus have I given you a summary of what Borellus hath from a long chain of most ingeniose Propositions and Theorems in fine inferred I come therefore to the. SECOND and last considerable proposed to be inquired viz. the Efficient Causes of this so wonderful Motive force of the Heart These seem to be no more than two of which one is immediate the other mediate As to the the former viz. the immediate cause of the hearts Motive Power we are not to expect to learn either what it is or whence it procedes from the doctrine of the Ancients For they having observed that the heart was not as all the other Muscles of the body are moved ad arbitrium voluntatis at the command of the Will not only named the motion of those Voluntary and the motion of this Natural as they had good reason to do but also conceived and taught the cause of the motion of the heart to be divers from the cause of the motion of the rest of the Muscles and accordingly constituted and assign'd to the heart a certain blind and unintelligible Pulsifick Faculty whereto alone they ascribed as well the diastole as the Systole thereof which they had no just reason to do To evince this their palpable error I will assert this PROPOSITION That the immediate Motive cause of the heart is the very same with that by which the Muscles of the Limbs are moved Voluntarily First it is most evident to sense that
little Canales within must therefore be full of small asperities it is necessary that the Succus Nervosus whose consistence is not much thinner than the white of an Egg well beaten should pass through them with a slow and interrupted course and at length fall out of their lower ends in drops with equal pauses between the drops Where we find a parility of Causes we may rightly expect a similitude of effects Here I see two formidable Difficulties standing like Romantick Giants in my way to deterr me from proceeding and I cannot without shame and infamy decline to encounter them One is That after the Cardiac Nerves are cut off and the heart itself taken out of the body the Pulsation of it continues for some time To remove this therefore I say that the cavities of the Nerves annext to the heart may remain still full of and turgid with the roscid Succus Nervosus which being hindred from regress by their spontaneous contraction toward the heart and kept in a state of fluxility by the yet lasting warmth of the heart may for some time be instilled into the Fibres of it and by swelling of them cause them to constringe the Ventricles as before Then the heart being irritated by the prick of a needle or some sharp and pungent liquor may be able by its peristaltic constriction to squeez out the few remaining drops of the roscid liquor Which being done the Pulsation ceaseth for ever To the bloud this effect ought not to be ascribed for after all reliques of it have been with warm water and a Syringe washed out of the Ventricles and squeez'd out of the Vessels the Pulsation notwithstanding will continue for sometime Nor can it be with more reason ascribed to Convulsions of the heart because all convulsions are disorderly and unequal both in the times of their girds and in those of their intermissions whereas in this case the Pulsations are regular and isochronical with equal pauses Nor to the Heat communicated by the bloud to the heart before it was exsected and not yet quite extinct because that borrowed heat soon vanishes and no external heat will revive the languishing Pulsation after all the roscid juice hath been exprest out of the ends of the Nerves left in the heart Nothing then remains to solve this Phaenomenon but the instillation of a few drops of our roscid liquor into the Fibres of the heart to swell them and so urge them to constriction of the Ventricles The other Difficulty is this Why is there not a Pulsation after the same manner also in all the Muscles of the Limbs since their Fibres are of the same nature in all things their disposition and direction only excepted since the Orifices of the Nerves perteining to them are in the Brain as open to admit and imbibe the Succus Nervosus there elaborate and provided for them and since the same Nerves are equally spongy and permeable in their constitution and so apt to transfer that liquor as the Orifices of the Cardiac Nerves are to receive or their Canales to transfer it If the whole apparatus be the same on both parts whence comes it that the same effect is not produced in both At this Goliah I have in my Scrip three Pebbles to throw and though my arm be weak I will not despair of hitting him in the forehead First therefore I say that it is not yet certainly known to any mortal man by what mediate cause the Muscles of the Limbs are moved at the command of the Will whether by simple contraction of the Originals of the Nerves inserted into them or by the immission of the Succus Nervosus more copiosely and swiftly at the time of their being put into action though the Mechanism of their Fibres make it more probable that they are moved by immission of some liquor from the Brain by which the rhomboid meshes or pores of their Fibres being all at the same time swell'd and dilated a contraction of the whole Muscle must in the same moment be effected and therefore I prefer this opinion to the former and have followed it in many places of this rude Discourse But yet this opinion hath not led me to a discovery of the Cause of the difference this present difficulty compells me to hunt after Should I imagine Valves affixt by Nature to the Orifices of the Nerves of the Muscles as Mons Des Cartes did in the bodies of them though such an artifice be not impossible yet beside that no such Valves have hitherto been found in the Brain I should still be to seek for a Cause to open and shut them ad arbitrium voluntatis and so should be put to a stand in my disquisition Which to avoid some other Organical contrivement such as may be not only possible but probable also and facile and fit to untie this Gordian knot must be excogitated Let it then be supposed that in the Brain the Orifices of the Nerves thence elonged to the Muscles of the Limbs and their Canales are in such a peculiar manner formed as at no time to take in and convey into the Muscles more of the roscid liquor than what is sufficient to nourish them and recruit their vigor unless when at the command of the Will under whose jurisdiction they properly are the Nerves being twitched up or convelled at their Originals both their Orifices are dilated to receive and their Canales rendred more pervious to transmit in a moment into the Fibres of the Muscles to be used a greater portion of the same invigorating liquor viz. so much as is requisite to swell them up by replenishing their pores and force them to contraction which is the common action of all Muscles On the other part let it be supposed that in the Brain Nature hath framed the Originals of the Cardiac Nerves by a different Artifice namely such as that not only their Orifices may always be open to imbibe but also their Canales so easily pervious to transmit the roscid liquor as that without any Vellication without any Convulsive motion the same liquor may merely by the plenitude of the Canales themselves be effused guttulatim into the Fibres of the heart to cause the alternate constriction or Pulsation of it And it is the more lawful for me to suppose this difference of structure in Nerves ordained for different uses because it is above all doubt that the Optick Nerves have a peculiar fabric and contexture wherein they differ from the Auditory and all other Nerves inservient to the rest of the external senses and that the Organ of every sense hath its nerve of a peculiar constitution accommodate to the nature of its proper object though those differences consist in such minute and subtle artifices as have hitherto eluded our most curiose researches though assisted by the best sort of Microscopes Why then may it not be thought that Nature hath given to the Cardiac Nerves also a constitution divers from that of all
composed of the degree of velocity and of the quantity of bloud impulsed as that excellent Mathematician Io. Alphonsus Borellus hath fully demonstrated By this stroke it is that the newly emptied and conniving porosities of the Muscles and Viscera are forced open and replenished with the impulsed bloud that communicates to them vital heat and fresh vigor and that the torpid useless and excrementitious particles there remaining are protruded and expelled partly through the pores of the skin partly through vessels destined to their transportation and expulsion So that by this rapid rushing in of the bloud nature attains to not only a reviving of the solid parts of the body but also to the expurgation of the bloud it self from its unprofitable and excrementitious parts in the Emunctories ordained for that office A third advantage is that by the same rapid velocity of the bloud and its vehement intrusion into the narrow meatus of the parts the current thereof dislodges rinses away and carries with it many other amoveable particles of various kinds Saline Sulphureous c. principally the reliques of the nutritive and nervose juices brought thither from the brain which though unprofitable now to the refection and invigoration of the parts in which they were left may yet be of some use to recruit and conserve the Crasis of the bloud and to expedite the secretion of its excrements This artifice of nature we may more easily comprehend by observing that the foreign particles now mentioned are extricated and rinsed away by the bloud not in ample vessels but after the egress of the bloud out of the Capillary Arteries in the intermediate spaces betwixt them and the Capillary Veins where end innumerable small Canales some of which bring in the nutritive and nervose liquors others export the superfluous and less profitable particles of them which small pipes are like the Capillary roots of plants almost every where disseminated into the fleshy parts into the Viscera and most frequently into the glandules And this seems to be done to the end that so many particles of these spiritual and noble juices being rinsed away by and commixt with the the bloud may advance and conserve the due consistence and constitution of it Now of these three considerable benefits no one seems to me possible to be attained otherwise than by the perpetual and rapid motion of the bloud Wherefore I am not destitute of a rational ground to support my conjecture that for these ends Nature thought fit to institute the swift motion of the bloud in its Circulation ¶ ⸪ But what may we conceive to be the reason that induced Her to institute also so multiplied a repetition of this course of the bloud through the same ways A River we know though the water be in a continual flux is yet still the same river because the elapsed parts are continually succeeded by new waters coming on with the same degree of speed to supply it But to maintain this perpetual succession and supply upon which the identity of the river necessarily depends there is required either an immense quantity of waters from a spring to feed the current or the same elapsed water must be brought back again to the fountain whence it flowed that so by perpetually reiterated circuitions the course of the river may be conserved which otherwise would soon fail and cease We are then no longer to admire that Nature having designed to bring the river of bloud with a most rapid course through the whole body of an Animal for the various ends above explained and resolved to make that course perpetual during the life of the Animal made use of the same expedient viz. to repete the circuition of the same bloud without intermission For the whole mass of bloud commonly found in the body of a man not exceding 20 pints and that quantity not sufficing to maintain the course above 5 or 6 first minutes of an hour lest the current might cease and so life also fail it was necessary that the circulation of the same mass of bloud should be continually reiterated for the conservation of life Besides this necessity there are many admirable uses and advantages which Nature brings to an Animal by often repeating the period of the circuition of the bloud through the same ways For if the Circulation were not in this manner reiterated the bloud could not be defaecated from its biliose excrement in the Liver nor according to the vulgar opinion from the matter of Urine in the Kidneys nor could either the Chyle be commixt with the bloud in the heart or the Lympha be brought to temper and dilute it in the Veins nor could various other operations necessary to the Animal oeconomy be performed All which it were not difficult for me to deduce from this repeted circuition of the Bloud if the shortness of the time appointed to me for the administration of my present province did not oblige me to pass by all collateral disquisitions and to peruse my principal Theme the Motion of the Bloud From the final causes of which I will therefore in a direct order procede to the Efficient ¶ ⸪ PRAELECTIO II. Of the Heart and its Pulsation TO measure the Divine Wisdom elucent in every Organ of an Animal by the short line of human Reason is indeed extreme folly and yet I doubt not to applaud and follow the counsel of Erasistratus who as Galen relates advised Physicians to solve all the actions naturally done in the body of an Animal by Mechanic Principles so far at least as the dim light of my limited understanding may serve to guide me in my researches For not to depend upon the authority of Plato who said 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉 that God always works by Geometry or of his greatest disciple Aristotle who from thence called God 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉 the Mechanic of the world we have the greater authority of the Sacred Scripture itself that God hath framed all things in number weight and measure Whoever therefore intends with due care to study any part of his works must therein chiefly consider number weight and measure i. e. the Mechanism of it otherwise in the end he will find his mind rather swell'd with opinion than fill'd with knowledge Why then may not we who are Christians as well as Natural Philosophers take those parts of an Animal to be Machines or Engines which evident reason and chiefly sense shew to be such or who hath prohibited us to investigate the formal reason and manner of their operations It is not more certain that no mortal can know enough of Gods works than it is that the more we are able to discover of his wisdom power and goodness discernible in the mirrour of his Creatures the more we shall find our selves obliged to admire love and adore him Equally certain it is also that no kind of devotion is more acceptable to him than that which procedes from knowledge of his infinite
seen that the liquor found in the Pericardium is easily capable of coagulation either by heat or cold so as to become like gelly of harts-horn or the white of an Egg hardned by boyling as the Serum of the bloud will do and observed the various little Glands seated about the Basis of the Heart for which I could find no other equally probable use as to instil the Serum into the Pericardium to facilitate the motion of the heart which most certainly that liquor doth as the humor instilled out of the glandulae lacrymales upon the outsides of the eyes serves to moisten and make them more easily moveable every way when I had I say observed and considered these things I rejected that thought and embraced this of the absorption of the reliques of the Succus Nervosus by the Veins of the heart The Second is that the Diastole of the Heart is caused partly by the Relaxation of the Fibres of it spontaneously restoring themselves to their natural posture and length as all other Tensile bodies are wont to do after they have been distended partly by the force of the bloud rushing out of the Ears into the Ventricles of the Heart and replenishing them Wherefore the Wisdom of Nature is admirable also in this that she ordained these Two Causes of the diastole viz. the relaxation of the Fibres and the influx of the bloud into the Ventricles to be exactly coincident that with united forces they might cooperate more efficaciously Whence it appears that in the diastole the Heart is not wholly Passive as all Anatomists hitherto have believed it to be For unless the Fibres did restore themselves to their former longitude which is a natural action at the same time the influx of the bloud happens certainly there could be no room to receive the bloud because the insides of the Ventricles would continue to touch each the other and so there could be no diastole The Third and last is that it appears from the whole Series of this discourse that the Pulsation or Constriction of the Heart hath its force from that Mechanic power which is called the Wedge and that the bloud is expressed out of the Heart by virtue of another Mechanic power which is named the Praelum or Press and consequently that the Heart itself is as all Automata are moved not by Spirits nor by a Pulsifick faculty nor by rarefaction of the bloud nor Ebullition or Fermentation of the bloud nor by explosion of Saline and Acid spirituose liquors but by Mechanick necessity Which from the beginning I hoped I should be able fairly to prove If the success of my endeavours hath not been answerable to that hope I will not go about to extenuate the blame of my faileur by citing examples of much greater Wits which have before me in vain attempted to reveal the same secret of Nature but consolate my self with this that my Iudges are men no less beloved for their exemplary candor and humanity than honoured for their excellency in all kind of Learning and who need not be put in mind That Truth is a tree whose root is in Heaven and of which even the wisest of us dim-sighted Mortals here upon earth see nothing but the shadow of its branches I will therefore conclude this inelaborate Disquisition with that memorable saying of the Prince of Roman Orators De his statuat unusquisque ut libet Quid autem verius sit Deus ipse viderit hominem quidem scire arbitror neminem ¶ ⸫ MY Lectures such as they are much Honour'd Auditors Ye have with obliging patience heard Be pleas'd I beseech ye to hear also before ye rise a word which I have to speak in my own defence Were it not indecent to compare small things with great I should venture perhaps to advertise you that the reasons which induced me to attempt a reformation of the Borellian Hypothesis of the Motion of the Heart which Doctor Harvey himself call'd the Sun of the Microcosm seem to have some kind of Analogy to those which moved the Prince of Astronomers Tycho Brahe to dislike the Ptolemaic System of the Macrocosm or greater World and to excogitate a new one of more probability and neatness For as Tycho animadverting that the Celestial Orbs had been by Ptolemy distributed unhansomly that so many and so great Epicycles were in vain imagined to explicate the retrogradations of the Planets and their various respects to the Sun and that the equality of the Circular motion was measured not from the Centre of its proper Circle as it ought but from the Centre of another Eccentric Circle against the first principles of Nature and Art invented a new System exempt from all these incommodities which is in truth the Copernican inverted So I conceiving that in the Borellian Hypothesis and Explosion of I know not what Saline and Acid materials in the Heart was not only in itself extremely improbable and incongruous to the Wisdom of Nature which always constitutes certain and regular Causes to produce certain and regular Effects but also unnecessarily supposed to solve the Phaenomenon of the Hearts Pulsation set my dull Brain on work to reform it and soon invented another that seems both free from those inconveniences and more agreeable to the Organical Structure of the Heart to which above all things it was requisite I should endeavour to adjust it This I thought my self obliged to signifie lest any here should believe either that I have usurped to my self this whole System of the Motion of the Heart from that most excellent Mathematician Alphonsus Borellus whose Memory I highly honour or that I lay claim to more than a Candid attempt to reform it ¶ ⸫ EPILOGUS PRAELECTIONVM quidem vela jam tandem contraxi nondum tamen dissolutam video concionem Resistamus igitur hîc parumper Auditores Ornatissim● si vobis ita videatur ad stupendam illam cujus rationem Mechanicam hactenus tam anxiè inquisivimus Cordis fabricam seriò respiciamus Inde enim etiamsi alia omnia in universitate rerum deessent Divinae Architecturae documenta cuivis hominum pronum est inferre quàm sit immensa illius caeterorumque omnium in hoc Mundo adspect abilium CONDITORIS solertia quámque parum ab immedicabili cùm animi tum mentis stupiditate olim abfuerit Epicurus Qui Animalia casu quodam in prima rerum procreatione genita fuisse vecorditer censuit opinatus est consequenter totam in iis membrorum varietatem dearticulationemque non aliunde quàm ex Atomorum fortè fortuna post infinitos inter se in spatio infinito vortices ita concurrentium atque commistarum dispositione extitisse Quamobrem neque ullam fuisse intelligentis Naturae prudentiam quae ossa cerebrum cor nervos venas quae oculos manus pedes viscera quae caetera omnia conformans ad fines certos seu functiones partibus congruas respexerit sed singulas partes ita