Selected quad for the lemma: cause_n

Word A	Word B	Word C	Word D	Occurrence	Frequency Band	MI	MI Band	Prominent
cause_n	body_n	nature_n	reason_n	1,625	5	4.6916	4	false

Text snippets containing the quad

ID	Title	Author	Corrected Date of Publication (TCP Date of Publication)	STC	Words	Pages
A11334	Opiologia: or, A treatise concerning the nature, properties, true preparation and safe vse and administration of opium For the comfort and ease of all such persons as are inwardly afflicted with any extreame griefe, or languishing paine, especially such as depriue the body of all naturall rest, and can be cured by no other meanes or medicine whatsoeuer. Dedicated to the illustrious, high and mighty lords, the estates generall of the vnited prouinces in the Netherlands. By Angelus Sala Vincentinus Venitus. And done into English, and something inlarged by Tho. Bretnor. M. M.	Sala, Angelus, 1576-1637.; Bretnor, Thomas, fl. 1607-1618, tr., ed.	1618 (1618)	STC 21594; ESTC S101645	41,817	118

substance_n of_o the_o body_n as_o all_o other_o vegetable_a and_o animal_n medicine_n may_v easy_o do_v in_o regard_n of_o that_o symbolisation_n they_o have_v with_o the_o foresay_a substance_n so_o that_o the_o stomach_n may_v reduce_v they_o into_o chyle_n at_o pleasure_n which_o be_v the_o cause_n also_o that_o the_o poison_n of_o evil_a plant_n serpent_n and_o other_o venomous_a creature_n be_v more_o active_a sudden_a and_o pierce_a then_o arsink_n itself_o or_o realgar_n mineral_n i_o can_v produce_v a_o number_n of_o other_o reason_n to_o demonstrate_v that_o chemical_a medicine_n of_o a_o vehement_a nature_n as_o principal_o the_o two_o before_o name_v against_o which_o all_o this_o controversy_n do_v particular_o arise_v be_v more_o gentle_a than_o any_o violent_a vomitive_a medicine_n which_o our_o ancient_n prescribe_v yea_o far_o more_o safe_a than_o any_o vomitorie_n under_o hellebore_n or_o any_o above_o name_v but_o to_o avoid_v long_a discourse_n let_v these_o suffice_v at_o this_o time_n now_o let_v we_o come_v to_o resolve_v ourselves_o whether_o those_o ordinary_a medicine_n which_o be_v natural_o gentle_a and_o without_o any_o offensive_a quality_n after_o chemical_a preparation_n change_v their_o natural_a mildness_n into_o that_o which_o be_v evil_a and_o so_o become_v vehement_a and_o dangerous_a concern_v which_o point_n we_o have_v in_o this_o discourse_n already_o speak_v some_o thing_n in_o defence_n of_o purgative_a medicine_n as_o those_o of_o more_o frequent_a use_n than_o other_o among_o disease_a person_n and_o therefore_o will_v be_v content_v to_o determine_v the_o whole_a matter_n in_o the_o general_a defence_n of_o diaphoreticke_n diuretic_n alexitery_n etc._n etc._n chemical_o prepare_v first_o therefore_o it_o must_v of_o necessity_n be_v grant_v of_o all_o opponent_n that_o every_o medicine_n ingenerall_n bereave_v of_o its_o earthiness_n and_o seculencie_n and_o make_v pure_a clean_o and_o well_o digest_v by_o fire_n must_v of_o consequence_n be_v less_o hurtful_a less_o dangerous_a and_o less_o offensive_a and_o be_v also_o far_o more_o apt_a to_o work_v ci●òtutò_fw-la &_o miundè_fw-la as_o the_o physician_n wish_v than_o any_o crude_a earthy_a impure_a or_o ill_o prepare_v medicine_n may_v or_o can_v do_v by_o any_o mean_n '_o possible_a the_o reason_n be_v that_o when_o such_o ill-prepared_n stuff_n be_v once_o get_v into_o the_o stomach_n of_o any_o disease_a person_n nature_n already_o struggle_v against_o the_o disease_n become_v thereby_o more_o weary_v over-cloyed_n and_o oppress_v in_o concoct_v and_o separate_n the_o pureness_n from_o the_o impurenesse_n of_o such_o drug_n than_o it_o be_v before_o and_o therefore_o can_v receive_v very_o little_a or_o no_o comfort_n at_o all_o by_o such_o medicine_n whereas_o on_o the_o contrary_a part_n other_o medicine_n make_v subtle_a active_a pure_a and_o well_o prepare_v by_o art_n do_v begin_v to_o disperse_v and_o dilate_v themselves_o gentle_o into_o all_o part_n of_o the_o body_n as_o soon_o as_o they_o be_v receive_v thereinto_o and_o be_v never_o so_o little_a exagitated_a or_o move_v by_o natural_a heat_n assist_v nature_n herself_o without_o any_o alteration_n or_o disturbance_n at_o all_o and_o like_o a_o good_a friend_n aid_n and_o promone_v she_o whereas_o the_o other_o weari_v and_o torment_v the_o body_n like_o a_o tyrant_n moreover_o we_o may_v consider_v that_o chemical_a medicine_n be_v pure_a and_o neat_a as_o aforesaid_a leave_v no_o feculent_a residence_n or_o corruption_n in_o the_o body_n at_o all_o as_o other_o common_o do_v but_o if_o it_o come_v to_o pass_v as_o it_o be_v not_o unlikely_a that_o some_o shall_v deny_v these_o reason_n object_v that_o chemical_a medicine_n be_v subtle_a and_o pure_a can_v more_o easy_o disturb_v nature_n and_o move_v the_o body_n more_o sudden_o than_o other_o medicine_n do_v to_o who_o we_o answer_v that_o although_o among_o our_o chemical_a medicine_n there_o be_v some_o of_o a_o subtle_a nature_n as_o our_o distil_a oil_n the_o quintessence_n of_o wine_n and_o other_o vegetable_n and_o as_o there_o be_v diverse_a liquor_n we_o acknowledge_v very_o sharp_a and_o pierce_a so_o in_o like_a manner_n be_v there_o some_o disease_n wherein_o such_o medicine_n be_v very_o requisite_a and_o necessary_a whereas_o other_o of_o a_o cross_n seculent_a and_o clammy_a substance_n can_v yield_v no_o ease_n or_o comfort_n at_o all_o in_o regard_n whereof_o we_o ought_v not_o to_o account_v they_o dangerous_a or_o hurtful_a but_o rather_o very_o beneficial_a and_o wholesome_a especial_o be_v well_o apply_v and_o use_v a●_n all_o medicine_n of_o what_o nature_n soever_o aught_o to_o be_v but_o under_o colour_n of_o these_o no_o man_n ought_v to_o comprehend_v other_o chemical_a medicine_n or_o proclaim_v they_o to_o be_v of_o such_o a_o pierce_a nature_n for_o come_v to_o purgative_a medicine_n extract_v be_v of_o a_o sappy_a thick_a and_o condense_a form_n we_o know_v well_o that_o they_o be_v not_o nor_o can_v be_v so_o subtle_a or_o pierce_a as_o oil_n nor_o be_v call_v subtle_a in_o regard_n of_o their_o penetrative_a virtue_n but_o rather_o because_o they_o be_v far_o more_o easy_o convert_v into_o liquor_n than_o the_o substance_n from_o whence_o they_o be_v extract_v and_o therefore_o ought_v in_o no_o ease_n to_o be_v call_v irritative_n experience_n herself_o teach_v we_o that_o the_o extract_n of_o mechoacan_n rheubarbe_n or_o sena_n be_v gentle_a medicine_n due_o administer_v show_v themselves_o far_o more_o mild_a gentle_a and_o effectual_a then_o when_o they_o be_v exhibit_v after_o a_o entire_a and_o gross_a preparation_n but_o what_o need_v many_o word_n do_v we_o not_o plain_o see_v that_o our_o chemical_a art_n bring_v colocynthis_fw-la and_o scammony_n acrimonious_a and_o venomous_a purgative_n ●o_o be_v so_o gentle_a and_o mild_a in_o operation_n that_o a_o man_n may_v as_o safe_o and_o free_o administer_v they_o as_o rheubarbe_n have_v only_a regard_n to_o the_o quality_n of_o the_o disease_n and_o the_o humour_n they_o natural_o purge_v as_o namely_o that_o of_o scammony_n whereof_o a_o man_n may_v bold_o give_v to_o one_o of_o a_o strong_a constitution_n twenty_o grain_n at_o a_o time_n in_o sugar_n rosat_n or_o any_o other_o conserve_v and_o this_o will_v work_v easy_o and_o well_o without_o any_o touch_n of_o pain_n perturbance_n or_o inflammation_n in_o the_o bowel_n as_o otherwise_o it_o will_v sure_o do_v and_o this_o be_v a_o maxim_n that_o not_o only_a scammony_n but_o every_o other_o purgative_a medicine_n of_o such_o venomous_a and_o vehement_a nature_n as_o hellebore_n tithymall_n etc._n etc._n lose_v their_o acrimonie_n and_o malign_a quality_n and_o by_o mean_n of_o this_o art_n become_v gentle_a and_o effectual_a in_o the_o extirpation_n of_o all_o such_o disease_n as_o they_o natural_o concern_v or_o respect_n without_o any_o inconvenience_n or_o danger_n at_o all_o and_o this_o be_v no_o vain_a conjecture_n of_o my_o own_o brain_n for_o i_o can_v produce_v a_o hundred_o sage_a and_o learned_a physician_n which_o can_n &_o will_v testify_v and_o make_v this_o good_a as_o well_o as_o myself_o and_o this_o be_v all_o which_o i_o purpose_v to_o speak_v at_o this_o time_n in_o defence_n of_o chemical_a medicine_n against_o the_o suggestion_n of_o scandalous_a tongue_n not_o meaning_n or_o intendeng_v hereby_o to_o disgrace_n or_o vilipend_v those_o ordinary_a medicine_n wherewith_o the_o world_n be_v and_o have_v be_v furnish_v and_o serve_v for_o so_o many_o age_n together_o for_o both_o the_o one_o and_o the_o other_o may_v be_v find_v good_a or_o evil_n according_a to_o the_o diversity_n of_o their_o usage_n notwithstanding_o i_o have_v at_o all_o time_n indevor_v myself_o to_o the_o uttermost_a of_o my_o power_n to_o amplify_v and_o illustrate_v the_o art_n of_o physic_n for_o the_o comfort_n of_o the_o disease_a as_o every_o one_o ought_v without_o any_o passion_n or_o malice_n in_o condemn_a thing_n new_o invent_v for_o paradox_n and_o heresy_n before_o due_a examination_n and_o trial_n ad_fw-la authorem_fw-la excuse_v i_o worthy_a sala_n if_o i_o chance_v for_o want_v of_o judgement_n thy_o intent_n to_o miss_v in_o fit_v that_o for_o england_n which_o for_o france_n thou_o pain_n haste_v take_v and_o labour_n to_o iwis_o for_o which_o and_o other_o thou_o deserve_v bliss_n i_o wish_v i_o be_v thy_o neighbour_n or_o that_o i_o with_o such_o a_o one_o may_v spend_v my_o day_n and_o die_v but_o now_o the_o world_n be_v such_o we_o can_v find_v a_o man_n with_o who_o we_o free_o may_v converse_v some_o proud_a some_o stately_a other_o so_o unkind_a that_o it_o grieve_v my_o heart_n their_o manner_n to_o rehearse_v or_o talk_v of_o such_o selfe-lover_n in_o my_o verse_n when_o man_n by_o nature_n friendly_a creature_n bear_v dote_v on_o themselves_o and_o other_o foul_o scorn_v but_o thou_o patavian-like_a i_o hear_v do_v joy_n to_o do_v poor_a scholar_n good_a and_o to_o

cappadocia_n galatia_n &_o cilicia_n to_o transport_v the_o same_o into_o persia_n india_n and_o europe_n and_o other_o part_n of_o the_o great_a turk_n dominion_n in_o africa_n and_o else_o where_o the_o which_o we_o shall_v have_v hardly_o believe_v if_o he_o have_v not_o relate_v to_o we_o by_o piecemeal_o as_o it_o be_v what_o quantity_n may_v be_v make_v and_o bring_v from_o each_o several_a village_n about_o the_o confine_n of_o carachora_n and_o the_o village_n of_o paphlagonia_n cappadocia_n armenia_n the_o less_o and_o gall●grecia_n he_o tell_v we_o moreover_o that_o the_o persian_n use_v it_o more_o abundant_o than_o the_o turk_n we_o desire_v one_o day_n to_o make_v a_o experiment_n and_o try_v how_o much_o opium_n a_o man_n can_v take_v at_o a_o time_n without_o any_o offence_n or_o hurt_n and_o we_o find_v that_o a_o certain_a janisarie_n of_o our_o acquaintance_n do_v use_v to_o eat_v thereof_o every_o day_n who_o take_v at_o one_o time_n in_o our_o presence_n the_o weight_n of_o half_a a_o dragme_n and_o meet_v with_o he_o the_o next_o day_n at_o a_o mercer_n shop_n we_o cause_v he_o to_o weigh_v we_o out_o a_o whole_a dragme_n which_o we_o give_v he_o and_o he_o swallow_v it_o up_o all_o at_o once_o without_o any_o danger_n or_o hurt_n at_o all_o save_v that_o for_o a_o while_o he_o seem_v like_o a_o drunken_a man_n to_z ●ate_z opium_n in_o turkey_n be_v no_o new_a thing_n and_o the_o reason_n why_o it_o be_v use_v so_o among_o they_o be_v because_o they_o persuade_v themselves_o that_o it_o make_v they_o more_o adventurous_a and_o less_o fearful_a of_o danger_n in_o war_n so_o that_o when_o the_o turk_n assemble_v or_o muster_v any_o great_a army_n together_o they_o make_v such_o havoc_n of_o their_o opium_n that_o they_o almost_o disfurnish_v the_o whole_a country_n they_o take_v it_o in_o as_o great_a snuff_n among_o they_o and_o account_v it_o as_o great_a a_o injury_n when_o one_o upbraid_v another_o with_o eat_v of_o opium_n as_o another_o countryman_n will_v do_v if_o one_o shall_v call_v he_o a_o drunkard_n a_o christian-armenian_a with_o who_o we_o lodge_v long_a time_n use_v many_o time_n to_o eat_v opium_n in_o our_o sight_n and_o prove_v the_o same_o ourselves_o we_o find_v no_o other_o accident_n save_v that_o it_o heat_v our_o stomach_n trouble_v something_o the_o brain_n and_o cause_v we_o to_o sweat_v in_o our_o sleep_n we_o think_v that_o if_o man_n be_v dispose_v they_o may_v as_o easy_o plant_v and_o sow_v poppy_n in_o france_n germany_n italy_n and_o some_o other_o place_n of_o europe_n as_o well_o as_o in_o asia_n if_o they_o will_v but_o take_v the_o pain_n to_o dress_v and_o gather_v it_o as_o they_o shall_v do_v for_o sure_o the_o climate_n of_o anatolia_n be_v as_o cold_a as_o that_o of_o france_n it_o be_v make_v in_o the_o same_o manner_n as_o author_n do_v describe_v but_o i_o be_o afraid_a if_o we_o have_v any_o bring_v over_o hither_o it_o be_v sophisticated_a &_o mingle_v for_o the_o merchant_n do_v questionless_a multiply_v it_o before_o they_o vent_v it_o abroad_o into_o the_o country_n and_o therefore_o because_o we_o know_v some_o mark_n and_o token_n how_o to_o choose_v the_o best_a it_o be_v not_o amiss_o to_o set_v down_o the_o same_o the_o best_a opium_n be_v that_o which_o be_v very_o bitter_a and_o so_o hot_a in_o taste_n that_o it_o will_v almost_o scorch_v and_o inflame_v the_o mouth_n it_o be_v in_o colour_n something_o yellowish_a or_o like_a to_o a_o lion_n skin_n and_o be_v form_v into_o a_o lump_n it_o seem_v speckle_v as_o a_o mass_n of_o diverse_a colour_n for_o in_o gather_v the_o say_a opium_n the_o seed_n be_v find_v cluster_v upon_o the_o poppie-head_n which_o be_v amass_v cleave_v together_o like_o a_o cake_n its_o smell_n be_v fulsome_a and_o strong_a and_o although_o it_o be_v account_v but_o of_o a_o cold_a temprature_n yet_o it_o many_o time_n scald_v the_o mouth_n opium_n be_v form_v into_o cake_n in_o the_o country_n of_o anatolia_n which_o exceed_v not_o above_o four_o ounce_n or_o half_a a_o pound_n at_o the_o most_o but_o the_o merchant_n to_o make_v the_o great_a profit_n by_o their_o sophistication_n double_v the_o aforesaid_a quantity_n for_o the_o subtle_a venetian_n make_v the_o cake_n in_o their_o shop_n to_o weigh_v a_o pound_n at_o least_o and_o this_o be_v the_o report_n of_o bellon_n concern_v opium_n now_o consider_v that_o in_o his_o time_n a_o man_n can_v hardly_o get_v any_o in_o christendom_n that_o be_v good_a how_o shall_v we_o find_v any_o now_o adays_o either_o in_o the_o apothecary_n or_o drugge_v shop_n which_o have_v these_o token_n or_o be_v so_o effectual_a or_o precious_a in_o its_o operation_n let_v pass_v the_o seed_n or_o grain_n as_o the_o only_a difference_n in_o gather_v it_o be_v call_v ordinary_o opium_n thebaicum_fw-la in_o respect_n of_o the_o province_n of_o thebes_n where_o the_o best_a be_v make_v chap._n ii_o of_o the_o assurance_n we_o have_v that_o opium_n may_v be_v use_v and_o take_v crude_a or_o mix_v in_o medicine_n without_o any_o prejudice_n or_o endanger_n the_o patient_n life_n at_o all_o a_o man_z shall_v find_v some_o physician_n now_o a_o day_n who_o adhere_v too_o much_o a_o conscience_n to_o the_o opinion_n of_o old_a leech_n capital_a enemy_n to_o opium_n its_o use_n do_v not_o only_o believe_v it_o as_o a_o article_n of_o their_o creed_n that_o whatsoever_o any_o author_n have_v say_v in_o detraction_n and_o disgrace_n of_o opium_n be_v a_o undoubted_a truth_n to_o who_o i_o answer_v and_o say_v that_o we_o ought_v not_o to_o submit_v ourselves_o to_o their_o judgement_n altogether_o nor_o to_o believe_v the_o opinion_n or_o say_n of_o any_o physician_n whether_o ancient_a or_o modern_a otherwise_o then_o daily_a observation_n of_o the_o use_n of_o thing_n &_o our_o grandam_n experience_n confirm_v in_o our_o understanding_n for_o truth_n for_o see_v that_o the_o ancient_a physician_n as_o well_o grecian_n as_o arabian_n how_o great_a or_o learned_a soever_o they_o be_v esteem_v yet_o be_v all_o but_o imperfect_a man_n and_o subject_a to_o error_n have_v their_o own_o proper_a passion_n and_o be_v full_a of_o contention_n and_o jealousy_n one_o against_o another_o as_o we_o be_v now_o adays_o whence_o it_o follow_v that_o we_o ought_v not_o to_o receive_v all_o their_o work_n for_o gospel_n without_o condition_n as_o aforesaid_a for_o as_o for_o example_n galen_n pliny_n and_o other_o put_v the_o world_n in_o fear_n and_o suspicion_n of_o opium_n and_o contrariwise_o oribasius_n diescorides_n and_o other_o commend_v it_o and_o assure_v and_o affirm_v it_o to_o be_v profitable_a and_o necessary_a for_o the_o cure_n of_o many_o disease_n who_o then_o in_o this_o case_n can_v give_v we_o better_o knowledge_n and_o satisfaction_n of_o truth_n of_o these_o thing_n than_o experience_v herself_o now_o she_o tell_v we_o that_o a_o man_n may_v safe_o use_v opium_n inward_o in_o man_n body_n oribasius_n therefore_o and_o diescorides_n have_v speak_v true_o whereas_o the_o error_n and_o abuse_n of_o other_o be_v manifest_v which_o howsoever_o it_o fall_v out_o it_o hinder_v we_o nothing_o at_o all_o to_o search_v into_o these_o thing_n see_v that_o neither_o cause_n nor_o reason_n can_v prejudice_n or_o hinder_v the_o authority_n of_o daily_a experience_n that_o the_o use_n of_o opium_n deserve_v to_o be_v applaud_v of_o all_o physician_n we_o have_v two_o principal_a and_o certain_a assurance_n whereof_o the_o former_a be_v not_o only_o the_o certification_n of_o peter_n bellon_n aforesaid_a but_o of_o a_o hundred_o honourable_a personage_n who_o have_v be_v in_o asia_n and_o affirm_v that_o the_o turk_n eat_v thereof_o in_o great_a quantity_n almost_o every_o day_n ordinary_o without_o any_o mischance_n or_o hurt_n to_o their_o body_n at_o all_o which_o may_v in_o part_n be_v a_o sufficient_a demonstration_n that_o opium_n be_v not_o a_o thing_n so_o venomous_a and_o dangerous_a to_o the_o life_n of_o man_n as_o some_o give_v out_o and_o proclaim_v it_o to_o be_v but_o here_o some_o to_o small_a purpose_n may_v tell_v i_o that_o the_o turk_n may_v easy_o digest_v opium_n how_o cold_a soever_o in_o regard_n of_o the_o hot_a clime_n they_o live_v in_o whereas_o the_o christian_n dwell_v under_o a_o cold_a in_o europe_n can_v do_v no_o such_o matter_n to_o who_o i_o answer_v that_o if_o it_o be_v grant_v that_o opium_n be_v of_o such_o quality_n as_o aforesaid_a yet_o whether_o a_o man_n can_v digest_v it_o or_o not_o can_v be_v physicallie_o attribute_v to_o the_o temprature_n of_o the_o climate_n but_o rather_o to_o the_o strong_a constitution_n or_o natural_a vigour_n of_o the_o people_n for_o the_o turk_n be_v from_o their_o very_a cradle_n more_o gross_o bring_v up_o and_o say_v then_o the_o christian_n be_v

opiologia_fw-la or_o a_o treatise_n concern_v the_o nature_n property_n true_a preparation_n and_o safe_a use_n and_o administration_n of_o opium_n for_o the_o comfort_n and_o ease_v of_o all_o such_o person_n as_o be_v inward_o afflict_v with_o any_o extreme_a grief_n or_o languish_a pain_n especial_o such_o as_o deprive_v the_o body_n of_o all_o natural_a rest_n and_o can_v be_v cure_v by_o no_o other_o mean_n or_o medicine_n whatsoever_o dedicate_v to_o the_o illustrious_a high_a and_o mighty_a lord_n the_o estate_n general_a of_o the_o unite_a province_n in_o the_o netherlands_o by_o angelus_n sala_n vincentinus_n venetus_n and_o do_v into_o english_a and_o something_o enlarge_v by_o tho._n bretnor_n m._n m._n london_n print_v by_o nicholas_n okes_n 1618._o to_o the_o learned_a and_o my_o worthy_o respect_a friend_n d._n bonham_n and_o master_n nicholas_n carter_n physician_n bee_n not_o offend_v worthy_a doctor_n if_o i_o presume_v to_o parallel_v you_o with_o a_o physician_n which_o netther_o be_v nor_o will_v be_v dub_v doct._n for_o any_o man_n pleasure_n nor_o care_v a_o whit_n for_o any_o clothing_n in_o bysse_n how_o worthy_a soe●er_n for_o the_o which_o i_o blame_v he_o the_o less_o since_o neither_o aesculapius_n hypocrates_n galen_n avicen_n nor_o any_o other_o of_o the_o old_a stamp_n ever_o assume_v any_o such_o title_n though_o better_a give_v they_o but_o tempora_fw-la mutantur_fw-la and_o therefore_o now_o adays_o for_o distinction_n and_o decorum_n sake_n it_o be_v very_o convenient_a and_o necessary_a to_o give_v such_o attribute_n especial_o to_o man_n endow_v with_o so_o excellent_a a_o quality_n as_o the_o true_a knowledge_n of_o physic_n and_o gift_n of_o heal_v be_v but_o how_o vile_o this_o worthy_a science_n and_o profession_n be_v traduce_v and_o abuse_v witness_v the_o multitude_n of_o mountebank_n quacksalver_n horseleech_n cunning-woman_n impostor_n and_o upstart_n who_o have_v learn_v my_o chance_n the_o calcine_v of_o mercury_n the_o preparation_n of_o antimony_n or_o the_o composition_n of_o some_o homespun_a medicine_n and_o have_v scrape_v together_o some_o trivial_a experiment_n out_o of_o some_o old_a manuscript_n or_o from_o some_o brazenfaced_a bragadotio_n will_v present_o forsooth_o set_n the_o physician_n at_o open_a defiance_n boast_v and_o protest_v that_o they_o have_v save_v the_o life_n of_o twenty_o who_o such_o and_o such_o a_o physician_n have_v quite_o forsake_v and_o give_v over_o for_o dead_a nay_o i_o have_v hear_v a_o good_a fellow_n i_o will_v not_o say_v a_o pharmacopaean_a and_o that_o no_o simple_a one_o neither_o bold_o affirm_v that_o if_o he_o shall_v not_o now_o and_o then_o add_v or_o diminish_v something_o from_o the_o physician_n bill_n the_o fat_a be_v in_o the_o fire_n and_o it_o be_v as_o much_o as_o the_o patient_n life_n be_v worth_a aggravate_v the_o matter_n in_o such_o manner_n that_o my_o very_a ear_n have_v glow_v to_o hear_v it_o see_v that_o by_o this_o their_o scandalous_a detraction_n they_o arrogate_v to_o themselves_o and_o impose_v upon_o the_o simple_a people_n bring_v they_o into_o fool_n paradise_n but_o the_o physician_n be_v well_o enough_o serve_v for_o if_o they_o will_v expulse_v one_o pack_n of_o these_o snaffle_n another_o and_o take_v a_o little_a pain_n with_o fernelius_n to_o prepare_v or_o see_v prepare_v their_o principal_a medicine_n and_o not_o to_o be_v so_o idle_a as_o to_o give_v too_o much_o credit_n to_o the_o druggist_n nor_o let_v each_o giddy-headed_n fellow_n be_v partaker_n of_o their_o secret_n it_o be_v doubtless_o better_a for_o the_o common_a wealth_n more_o profitable_a unto_o themselves_o and_o more_o please_v unto_o god_n but_o of_o this_o enough_o there_o rest_v nothing_o now_o my_o worthy_a friend_n but_o that_o you_o will_v vouchsafe_v to_o stand_v betwixt_o i_o and_o such_o malicious_a detractor_n for_o if_o they_o dare_v baspheme_v the_o tall_a cedar_n what_o will_v they_o not_o do_v unto_o the_o low_a shrub_n the_o subject_n of_o this_o treatise_n be_v so_o well_o know_v unto_o you_o that_o howsoever_o some_o nice_a and_o scrupulous_a person_n may_v make_v question_n of_o the_o verity_n of_o the_o passage_n or_o of_o the_o safety_n and_o excellency_n of_o the_o medicine_n you_o be_v so_o well_o instruct_v in_o the_o composition_n and_o virtue_n thereof_o that_o no_o wise_a man_n will_v oppose_v you_o some_o may_v imagine_v that_o i_o may_v have_v make_v better_a choice_n of_o some_o famous_a and_o remarkable_a collegian_n for_o my_o patron_n but_o unto_o you_o only_o and_o unto_o that_o worthy_a doctor_n gwin_n be_o i_o oblige_v who_o multiplicity_n of_o learning_n judgement_n and_o discretion_n accompany_v with_o affability_n humanity_n and_o courtesy_n be_v more_o than_o apparent_o know_v to_o all_o your_o acquaintance_n let_v i_o therefore_o crave_v this_o boon_n at_o your_o hand_n that_o you_o will_v accept_v this_o simple_a translation_n as_o a_o testimony_n of_o my_o love_a remembrance_n towards_o you_o and_o that_o you_o will_v defend_v it_o from_o the_o obtrectation_n of_o scandalous_a tongue_n and_o you_o shall_v ever_o make_v i_o you_o tho._n bretnor_n to_o the_o ingenious_a and_o indifferent_a reader_n the_o cause_n move_v i_o courteous_a reader_n to_o translate_v and_o publish_v this_o small_a pamphlet_n be_v not_o only_o the_o scarcity_n of_o the_o french_a copy_n but_o the_o especial_a want_n of_o such_o a_o treatise_n in_o our_o own_o mother-tongue_n for_o not_o only_o the_o rude_a multitude_n and_o man_n of_o some_o judgement_n through_o vain_a delusion_n and_o superstitious_a fear_n but_o many_o physician_n themselves_o through_o a_o galenicall_a persuasion_n make_v no_o small_a question_n and_o scruple_n whether_o opium_n may_v be_v take_v inward_o or_o not_o nay_o i_o have_v know_v man_n of_o good_a discretion_n so_o far_o infatuate_v by_o conceit_n and_o hear_v say_v as_o they_o have_v rather_o choose_v to_o endure_v intolerable_a pain_n than_o they_o will_v take_v three_o poor_a grain_n of_o well_o prepare_v laudanum_n but_o i_o can_v great_o blame_v they_o for_o the_o naked_a truth_n be_v many_o modern_a physician_n know_v not_o well_o what_o to_o make_v of_o it_o forestus_n montanus_n and_o many_o other_o with_o galen_n absolute_o conclude_v that_o it_o be_v stupify_a and_o cold_a in_o the_o four_o degree_n at_o least_o and_o therefore_o not_o fit_a to_o be_v inward_o take_v at_o all_o but_o in_o syncopes_fw-la and_o extreme_a necessity_n mercatus_n be_v indifferent_a capivaccius_fw-la be_v force_v by_o common_a experience_n to_o grant_v with_o avicen_n that_o for_o its_o four_o degree_n of_o coldness_n it_o be_v furnish_v with_o three_o of_o heat_n in_o operation_n but_o platerus_n bauhinus_n zwingerus_fw-la scaliger_n quercitanus_n and_o other_o affirm_v with_o rhasis_n that_o opium_n be_v rather_o hot_a then_o cold_a see_v that_o in_o taste_v thereof_o it_o do_v palatum_fw-la &_o linguam_fw-la urere_fw-la caput_fw-la tentare_fw-la sudorem_fw-la provocare_fw-la venerem_fw-la promovere_fw-la sitim_fw-la excitare_fw-la pruritum_fw-la insignem_fw-la parere_fw-la animositatem_fw-la fi●e_fw-la potius_fw-la furorem_fw-la inducere_fw-la and_o be_v outward_o apply_v do_v contrary_a to_o all_o cold_a thing_n blister_v the_o skin_n discuss_v and_o mollify_v hard_a tumour_n and_o nodes_fw-la but_o whether_o it_o be_v hot_a or_o cold_a it_o skill_v not_o much_o see_v it_o be_v confess_v of_o all_o true_a physician_n that_o it_o do_v ex_fw-la forma_fw-la specifica_fw-la natural_o resist_v putrefaction_n and_o wonderful_o and_o speedy_o release_v the_o body_n from_o intolerable_a pain_n for_o let_v the_o torment_n or_o grief_n proceed_v from_o what_o cause_n soever_o either_o hot_a or_o cold_a inward_a or_o outward_a it_o work_v the_o same_o effect_n so_o that_o this_o only_a medicine_n well_o prepare_v will_v doubtless_o save_v many_o thousand_o man_n life_n that_o travail_n or_o fail_v sub_fw-la aequatore_fw-la vel_fw-la polo_fw-la arctico_fw-la into_o the_o east_n indies_n or_o northern_a discovery_n under_o the_o hot_a or_o cold_a clime_n in_o the_o world_n see_v it_o resemble_v much_o the_o oil_n of_o vitriol_n vinegar_n chemical_a salt_n and_o such_o like_a which_o be_v give_v with_o good_a success_n as_o well_o in_o cold_a as_o hot_a disease_n but_o what_o need_v many_o word_n see_v the_o author_n himself_o have_v sufficient_o discover_v the_o benefit_n hereof_o i_o only_o wish_v you_o to_o have_v great_a regard_n to_o its_o preparation_n for_o as_o in_o most_o physical_a drug_n there_o remain_v some_o bad_a quality_n or_o other_o which_o need_v correction_n so_o do_v opium_n require_v vulcan_n help_n and_o other_o specifical_a mean_n to_o drive_v away_o its_o sulphurous_a malignity_n you_o may_v read_v in_o quercetane_n his_o answer_n to_o anonymous_n cap._n 2._o and_o in_o sennertus_n his_o institution_n lib._n 5._o part_n 3._o sect._n 2._o cap._n 1._o that_o the_o ancient_a father_n of_o physic_n make_v their_o chief_a medicine_n with_o their_o own_o hand_n and_o entitle_v they_o

ingenerall_n become_v not_o only_o more_o able_a body_v and_o strong_a thereby_o but_o also_o more_o apt_a and_o able_a to_o eat_v and_o digest_v diverse_a thing_n which_o the_o tender_a and_o nice_a christian_n can_v iudure_v and_o that_o the_o truth_n be_v so_o let_v we_o but_o consider_v a_o little_a the_o difference_n of_o natural_a toughness_n and_o strength_n between_o a_o christian_a paysant_n or_o carle_n here_o among_o we_o and_o a_o gentleman_n or_o citizen_n do_v not_o we_o see_v i_o pray_v you_o that_o the_o paysant_n can_v more_o easy_o endure_v a_o purgation_n make_v of_o white_a hellebore_n tithymall_n euphorbium_n or_o colocynthis_fw-la which_o be_v account_v violent_a and_o venomous_a medicine_n than_o these_o tender_a spark_n aforesaid_a can_v brook_v rheubarbe_n mechoacan_n sena_n aloe_n or_o the_o damask_n rise_v but_o why_o the_o turk_n devour_v opium_n on_o this_o fashion_n ought_v rather_o to_o be_v impute_v unto_o a_o ordinary_a custom_n and_o common_a usage_n among_o they_o then_o to_o any_o other_o cause_n whatsoever_o even_o as_o the_o indian_n be_v accustom_v to_o take_v tobacco_n which_o be_v a_o plant_n not_o only_o narcoticke_a and_o stupefactive_a but_o of_o a_o violent_a and_o extreme_a vomitive_a quality_n also_o notwithstanding_o we_o see_v that_o christian_n all_o europe_n over_o by_o little_a and_o little_o have_v bring_v themselves_o into_o such_o a_o custom_n and_o habit_n thereunto_o that_o they_o feel_v no_o alteration_n or_o prejudice_n at_o all_o as_o they_o think_v by_o the_o use_n thereof_o i_o make_v no_o question_n but_o a_o man_n may_v find_v a_o number_n of_o people_n among_o christian_n that_o if_o they_o can_v already_o can_v easy_o accustom_v themselves_o to_o eat_v opium_n as_o familiar_o as_o they_o take_v tobacco_n although_o they_o can_v not_o use_v ●t_z in_o such_o quantity_n nor_o so_o often_o in_o regard_n it_o be_v a_o pure_a essence_n and_o extract_n which_o nature_n have_v separate_v from_o its_o plant_n for_o essential_a thing_n be_v always_o far_o more_o effectual_a than_o gross_a be_v for_o confirmation_n whereof_o we_o need_v not_o doubt_v that_o if_o a_o man_n shall_v separate_v the_o rosinous_a and_o sulphurous_a substance_n of_o tobaccao_n and_o bring_v it_o into_o such_o a_o consistence_n as_o opium_n be_v and_o afterward_o give_v it_o unto_o such_o as_o usual_o take_v tobacco_n they_o can_v not_o possible_o endure_v the_o ten_o part_n so_o much_o of_o this_o as_o of_o the_o leaf_n as_o have_v be_v already_o practise_v and_o try_v there_o be_v some_o empiric_n i_o know_v which_o give_v crude_a opium_n to_o their_o patiens_fw-la in_o as_o great_a or_o great_a quantity_n at_o a_o time_n than_o discorides_n have_v limit_v and_o that_o without_o any_o great_a danger_n or_o hazard_n of_o life_n at_o all_o only_o correct_v it_o a_o little_a with_o the_o powder_n of_o carawayseed_n and_o in_o case_n of_o necessity_n i_o myself_o will_v not_o stick_v or_o make_v any_o scruple_n to_o use_v it_o yea_o i_o dare_v if_o need_n be_v take_v two_o or_o three_o grain_n thereof_o at_o a_o time_n myself_o for_o although_o i_o never_o do_v eat_v thereof_o hitherto_o indeed_o yet_o have_v i_o often_o taste_v the_o same_o and_o also_o receive_v great_a quantity_n of_o the_o sulphurous_a vapour_n both_o into_o my_o stomach_n and_o head_n in_o time_n of_o the_o preparation_n thereof_o without_o any_o perceivance_n or_o the_o least_o touch_n of_o any_o offence_n in_o the_o world_n nevertheless_o it_o be_v not_o my_o counsel_n that_o any_o physician_n shall_v use_v it_o crude_a in_o this_o manner_n see_v we_o have_v art_n and_o mean_n to_o prepare_v it_o otherwise_o the_o second_o assurance_n that_o we_o have_v concern_v the_o use_n of_o opium_n be_v in_o that_o we_o find_v and_o see_v that_o the_o most_o expert_a and_o wise_a physician_n of_o old_a find_v it_o good_a and_o therefore_o prescribe_v this_o medicine_n as_o a_o principal_a ingredient_n and_o as_o one_o of_o the_o most_o important_a base_n in_o their_o chief_a composition_n alexitery_n diaphoreticke_n anodynes_n cordial_n which_o natural_o resist_v the_o most_o grievous_a and_o violent_a disease_n that_o can_v any_o way_n happen_v to_o human_a body_n for_o which_o cause_n they_o usual_o call_v they_o opiate_n confection_n as_o that_o of_o their_o treacle_n of_o andromachus_n their_o mithridate_n of_o danocrates_n their_o triphera_n magna_fw-la aurea_fw-la alexandrina_n philomuim_n romanum_fw-la requies_fw-la nicholai_n and_o other_o which_o they_o have_v use_v as_o principal_a medicine_n for_o these_o many_o hundred_o year_n and_o yet_o do_v for_o they_o be_v indeed_o the_o most_o precious_a and_o necessary_a composition_n their_o ordinary_a apothecary_n have_v the_o cause_n which_o move_v ancient_a physician_n to_o put_v opium_n unto_o the_o foresay_a confection_n be_v not_o few_o see_v that_o its_o property_n be_v to_o assuage_v all_o inward_a pain_n strengthen_v the_o passage_n &_o conduit_n which_o be_v open_a loose_a &_o disband_v precipitate_v disperse_v and_o consume_v these_o venomous_a vapour_n which_o be_v raise_v from_o one_o part_n to_o another_o incrassat_fw-la and_o thicken_v all_o subtle_a corrosive_n &_o humour_n by_o correct_v their_o malignity_n and_o acrimonie_n stop_v and_o stay_v all_o flux_n as_o well_o dysenterick_n as_o menstrual_a appease_v and_o extinguish_v all_o extremity_n in_o burn_a fever_n provoke_v natural_a rest_n and_o sleep_v to_o distress_a and_o lunatic_n person_n and_o final_o like_o a_o balm_n defend_v the_o part_n from_o corruption_n which_o operation_n and_o effect_n be_v require_v in_o all_o composition_n which_o be_v general_o ordain_v to_o resist_v the_o violence_n of_o diverse_a disease_n in_o appease_v and_o repel_v whereof_o some_o of_o these_o property_n before_o name_v be_v ordinary_o desire_v as_o quercetanus_n in_o his_o pharmacop●a_n entreat_v of_o the_o vetues_fw-la of_o opium_n affirm_v in_o these_o word_n say_v pauci_fw-la en●m_fw-la sunt_fw-la morbi_fw-la qui_fw-la non_fw-la simul_fw-la complacentur_fw-la vel_fw-la ardoribus_fw-la vel_fw-la inflammationibus_fw-la vel_fw-la inquietudinibus_fw-la commotiomibus_fw-la la●guoribus_fw-la oppressionibus_fw-la vigilijs_fw-la de●luxionibus_fw-la vel_fw-la var●●_n generis_fw-la doloribus_fw-la capitis_fw-la pectoris_fw-la ventricul●_n ventris_fw-la vel_fw-la cu●scunque_fw-la alterius_fw-la patris_fw-la ad_fw-la quorum_fw-la omnium_fw-la symptomatum_fw-la ferociam_fw-la compescendam_fw-la opium_n specificam_fw-la &_o peculiarem_fw-la quandam_fw-la habet_fw-la proprietatem_fw-la qua_fw-la vel_fw-la unum_fw-la exhis_fw-la symptomatis_n seorsim_fw-la vel_fw-la plura_fw-la cum_fw-la malo_fw-la coniuncta_fw-la simul_fw-la cum_fw-la admirabili_fw-la astantium_fw-la &_o ipsorum_fw-la aegrorum_fw-la admiratione_n evincit_fw-la ac_fw-la subigit_fw-la unde_fw-la saepeumerò_fw-la in_o e●usmodi_fw-la casibus_fw-la tam_fw-la mirandos_fw-la sanationum_fw-la effectus_fw-la prodere_fw-la videmus_fw-la theriacam_n muhridatium_fw-la antidotos_fw-la esdrae_fw-la &_o simile_n quae_fw-la opium_n exciiunt_fw-la etc._n etc._n for_o there_o be_v very_o few_o disease_n which_o be_v not_o either_o accompany_v with_o heat_n inflammation_n inquietude_n perturbation_n languish_v oppression_n watch_v flux_n etc._n etc._n for_o mitigate_a and_o ●epressing_v of_o which_o symptom_n opium_n have_v a_o specifical_a and_o a_o certain_a peculiar_a propriety_n etc._n etc._n and_o this_o may_v serve_v to_o assure_v we_o that_o we_o may_v bold_o use_v opium_n inward_o without_o any_o prejudice_n to_o life_n yea_o rather_o for_o its_o better_a conservation_n be_v administer_v with_o judgement_n and_o discretion_n as_o all_o other_o medicine_n whatsoever_o ought_v to_o be_v chap._n iii_o concern_v the_o good_a and_o evil_a affect_n which_o opium_n may_v produce_v in_o man_n body_n that_o opium_n as_o aforesaid_a be_v wise_o administer_v to_o the_o disease_a produce_v in_o they_o many_o good_a effect_n and_o contrariwise_o abuse_v excit_v diverse_a dangerous_a and_o mortal_a accident_n be_v in_o no_o sort_n doubt_v among_o discreet_a physician_n but_o touch_v the_o cause_n why_o opium_n do_v work_v these_o effect_n in_o man_n body_n be_v disputable_a for_o most_o physician_n impute_v it_o to_o that_o extremity_n of_o the_o four_o degree_n of_o coldness_n wherewith_o it_o be_v endow_v and_o for_o proof_n and_o confirmation_n hereof_o they_o produce_v a_o argument_n draw_v from_o the_o effect_n of_o its_o operation_n in_o this_o manner_n opium_n say_v they_o provoke_v a_o vigilant_a or_o watchful_a man_n to_o sleep_v and_o incrass_v thin_a and_o subtle_a humour_n vigilancy_n then_o proceed_v for_o the_o most_o part_n from_o a_o hot_a and_o dry_a cause_n with_o matter_n or_o without_o and_o the_o dissolution_n also_o of_o the_o humour_n from_o the_o like_a distemperature_n opium_n therefore_o contrary_v and_o impugn_v the_o cause_n of_o these_o effect_n must_v needs_o be_v of_o the_o quality_n aforesaid_a and_o for_o the_o further_a confirmation_n hereof_o they_o allege_v galen_n plini●_n and_o other_o who_o in_o like_a manner_n witness_n that_o when_o opium_n be_v undiscreet_o use_v it_o cause_v lethargic_a sleep_n privation_n of_o sense_n stupe●_n faction_n of_o

critick●_n beside_o the_o purpose_n will_v hit_v i_o a_o blow_n on_o the_o blind_a side_n say_v how_o come_v it_o to_o pass_v that_o these_o brave_a spag●riques_n heal_v not_o all_o the_o patient_n that_o fall_v into_o their_o hand_n see_v they_o brag_v of_o such_o singular_a secret_n as_o these_o of_o who_o i_o demand_v the_o cause_n also_o why_o they_o cure_v not_o all_o they_o have_v such_o grave_a institution_n solid_a ground_n and_o principal_a medicine_n use_v ordinary_o among_o they_o this_o be_v not_o to_o prove_v that_o although_o chemical_a medicine_n work_v more_o citò_fw-la tutó_n &_o iucundè_fw-la by_o reason_n of_o their_o better_a preparation_n and_o exaltation_n in_o power_n then_o other_o ordinary_a medicine_n that_o therefore_o they_o can_v sure_o overcome_v and_o cure_v all_o hereditary_a inbred_a and_o incurable_a disease_n or_o such_o other_o which_o god_n for_o the_o exercise_n of_o his_o justice_n have_v inflict_v and_o confirm_v upon_o the_o body_n of_o man_n in_o such_o sort_n that_o no_o medicine_n nor_o skill_n in_o the_o world_n can_v cure_v for_o ni_fw-fr deus_fw-la affuerit_fw-la viresque_fw-la in_o fuderit_fw-la herbis_fw-la quid_fw-la rogo_fw-la dyctamnus_fw-la quid_fw-la pavacaea_n invent_v if_o god_n help_v not_o and_o into_o herb_n infuse_v a_o work_a power_n in_o vain_a we_o medicine_n use_v in_o his_o book_n de_fw-fr morbis_fw-la resolutis_fw-la in_o his_o first_o book_n of_o mineral_n disease_n and_o in_o diverse_a other_o passage_n of_o his_o work_n he_o make_v mention_n of_o opium_n with_o such_o great_a honour_n and_o respect_n as_o any_o ancient_a physician_n in_o commendation_n thereof_o ever_o do_v afterward_o concern_v its_o usage_n he_o mean_v not_o that_o any_o man_n shall_v administer_v it_o simple_a and_o crude_a or_o gross_o temper_v and_o mix_v with_o other_o medicine_n before_o the_o due_a preparation_n for_o in_o his_o first_o chapter_n de_fw-fr sulphur_n embryonato_n and_o his_o first_o book_n de_fw-fr reb._n nat_n he_o aff●●neth_v that_o opium_n mandrake_n and_o henbane_n contain_v in_o they_o some_o malign_a substance_n in_o regard_n whereof_o no_o man_n ought_v to_o use_v they_o if_o he_o work_v wary_o before_o he_o have_v reduce_v they_o into_o a_o quintessentiall_a f●rme_n which_o indeed_o have_v be_v the_o principal_a occasion_n that_o the_o spagiricke_a physician_n put_v their_o hand_n to_o the_o plough_n have_v find_v the_o m●anes_n to_o prepare_v opium_n into_o such_o a_o precious_a and_o profitable_a medicine_n that_o in_o all_o spagi●icall_a and_o ordinary_a practice_n whatsoever_o none_o other_o can_v be_v comparable_a either_o for_o speedy_a or_o wonderful_a operation_n for_o w●ich_v only_a medicine_n all_o christian_a physician_n and_o people_n which_o know_v it_o be_v eternal_o bind_v to_o give_v the_o fountain_n of_o all_o goodness_n thanks_n for_o his_o gracious_a gift_n inspire_v into_o man_n chap._n v._o of_o the_o invention_n or_o mean_n how_o to_o prepare_v opium_n well_o and_o wherein_o it_o general_o cons●●steth_v have_v hitherto_o diverse_o discourse_v of_o opium_n in_o demonstrate_v its_o precious_a and_o necesarie_a use_n in_o physic_n we_o 〈◊〉_d now_o go_v about_o to_o show_v th●●_n effectual_a manner_n of_o preparation_n which_o the_o spagirist_n use_v to_o the_o end_n we_o may_v more_o fre●l●_n and_o safe_o administer_v the_o same_o than_o the_o ancient_a physician_n do_v who_o common_o put_v the_o same_o into_o their_o medicine_n unprepared_a which_o quercetanus_n in_o his_o pharm_n dog_n r●st_n p●●_n 186._o treat_v of_o the_o composition_n of_o tre●kle_n mighty_o complain_v of_o in_o these_o word_n say_v de_fw-fr plorandus_fw-la enim_fw-la error_n est_fw-la nobilis_fw-la hui●●_n alexipharmaci_fw-la compositioni_fw-la in_o tam_fw-la magna_fw-la trium_fw-la scilicet_fw-la unciarum_fw-la dosi_fw-la ad_fw-la miscere_fw-la tantum_fw-la ven●nun_fw-la quale_fw-la opium_n crudum_fw-la &_o minus_fw-la praeparatum_fw-la esse_fw-la constat_fw-la the_o error_n of_o they_o be_v great_o to_o be_v lament_v etc._n etc._n which_o quercetanus_n avouch_v not_o to_o blame_v the_o invention_n of_o ancient_a physician_n nor_o the_o virtue_n of_o treacle_n which_o ●ath_v be_v and_o yet_o be_v daily_o use_v with_o great_a success_n but_o rather_o to_o insinuate_v and_o show_v ●ow_o much_o more_o wary_o &_o safe_o they_o shall_v ●ave_n deal_v in_o the_o usage_n of_o opium_n than_o they_o ●ave_n do_v heretofore_o if_o they_o have_v as_o true_o know_v the_o art_n spagiricke_n as_o we_o do_v now_o ●d●ies_v how_o be_v it_o we_o ought_v notwithstanding_o to_o take_v these_o thing_n in_o good_a part_n which_o ●hey_n have_v reveil_v unto_o we_o according_a to_o their_o experience_n although_o the_o invention_n of_o the_o ●rue_a preparation_n of_o opium_n aught_o by_o all_o ●eanes_n to_o be_v ascribe_v to_o theophrastus_n para●elsus_n as_o principal_a and_o chief_a of_o the_o natural_a philosopher_n and_o spagirist_n who_o have_v general_o write_v of_o the_o chemical_a preparation_n of_o all_o thing_n in_o a_o manner_n which_o be_v use_v in_o physic_n where_o other_o on_o the_o contrary_n increat_v of_o the_o philosophers-stone_n have_v bu●●ed_v themselves_o to_o besot_v and_o fool_v the_o world_n ●nd_v by_o that_o mean_n have_v rather_o seduce_v man_n understanding_n than_o produce_v any_o ●●od_a fruit_n or_o work_n of_o worth_n now_o the_o best_a preparation_n of_o opium_n consi_v in_o three_o principal_a practice_n the_o first_o 〈◊〉_d deprive_v or_o take_v from_o it_o its_o oleaginous_a or_o sulphurous_a substance_n wherein_o principal_o consist_v the_o evil_a narcoticall_a and_o ●upefactive_a quality_n the_o second_o in_o correct_v and_o mitigate_a its_o causticke_a and_o ad●●ing_a acrimonie_n wherein_o it_o be_v almost_o parallel_v unto_o tithymall_n spurge_n and_o other_o lactiferous_a corrosive_n and_o the_o three_o in_o accompany_v or_o mix_v there_o with_o some_o suc●_n good_a additament_n and_o furtherer_n as_o shalb●_n describe_v hereafter_o chap._n vi_o contain_v three_o manner_n or_o way_n to_o depri●●_n opium_n from_o its_o nar●oticall_a stupefactive_a an●_n nuisible_a sulphur_n which_o must_v be_v do_v before_o its_o essential_a extract_n can_v be_v draw_v it_o be_v former_o say_v that_o opium_n be_v deprive_v and_o free_v from_o its_o malignity_n three_o manner_n of_o way_n the_o first_o as_o paracelsus_n in_o his_o second_o book_n d●_n morbis_fw-la amentium_fw-la say_v be_v by_o take_v opium_n and_o mix_v therewith_o certain_a aromatical_a thing_n and_o reduce_v they_o into_o a_o ma●●_n with_o the_o rob_v or_o ivice_n of_o quince_n and_o afterward_o put_v they_o into_o a_o quince_n who_o core_n be_v first_o take_v out_o and_o last_o have_v cover_v or_o enfold_v the_o same_o in_o past_a bak●_n it_o in_o a_o oven_n like_o bread_n and_o be_v take_v out_o reduce_v or_o beat_v it_o into_o powder_n and_o infuse_v i●_n in_o some_o convenient_a liquor_n whereby_o the_o essense_n or_o tincture_n thereof_o may_v be_v extract_v to_o which_o purpose_n he_o take_v the_o spirit_n of_o vitriol_n compose_v against_o the_o epilepsy_n as_o a_o specifical_a furtherer_n in_o this_o case_n the_o second_o mean_n be_v to_o take_v opium_n and_o to_o cut_v it_o into_o small_a slice_n and_o to_o put_v it_o into_o ●a_o clean_a frying-pan_n or_o upon_o a_o lamine_n or_o broad_a plate_n of_o iron_n and_o with_o a_o gentle_a fire_n evaporate_v away_o its_o sulphur_n which_o will_v exhale_v or_o fume_v away_o like_o a_o gross_a and_o stink_a smoke_n from_o which_o smell_v it_o be_v no●_n amiss_o to_o abstain_v as_o much_o as_o may_v be_v some_o in_o the_o interim_n sprinkle_v it_o with_o a_o little_a rose_n vinegar_n and_o stir_v it_o together_o with_o a_o spatula_fw-la or_o slice_v as_o it_o melt_v like_o aloe_n and_o after_o spread_v it_o abroad_o upon_o the_o say_a lamine_n of_o iron_n and_o so_o let_v it_o evapour_n away_o as_o long_o as_o any_o fume_n will_v arise_v and_o until_o it_o become_v so_o dry_a that_o it_o may_v be_v powder_v always_o beware_v that_o it_o burn_v not_o this_o manner_n of_o preparation_n be_v approve_v for_o good_a of_o quercetane_n and_o many_o other_o modern_a physician_n and_o i_o myself_o also_o always_o observe_v the_o same_o method_n when_o i_o have_v occasion_n to_o make_v any_o laudanum_n for_o my_o own_o use_n the_o three_o way_n be_v to_o dissolve_v the_o crude_a opium_n in_o some_o convenient_a liquor_n as_o be_v say_v and_o let_v it_o digest_v and_o boil_v easy_o still_o scum_v away_o the_o froth_n and_o unctuous_a cremor_n swim_v aloft_o which_o indeed_o be_v its_o sulphurous_a malignity_n and_o reserve_v the_o rest_n for_o use_v this_o manner_n of_o preparation_n be_v high_o commend_v of_o crollius_n in_o his_o basilica_n chymica_fw-la in_o the_o chapter_n entreat_v of_o laudanum_n of_o these_o three_o manner_n of_o prepare_v opium_n before_o it_o be_v bring_v to_o a_o extract_n let_v every_o physician_n make_v his_o own_o choice_n chap._n vii_o how_o the_o ●incture_n quintessence_n or_o as_o some_o call_v it_o the_o substance_n

in_o my_o laudanum_n than_o you_o see_v not_o only_o because_o i_o find_v the_o foresay_a tincture_n of_o gold_n to_o be_v as_o sufficient_a and_o available_a as_o all_o the_o rest_n but_o for_o some_o other_o rational_a consideration_n which_o here_o i_o spare_v to_o speak_v of_o 5_o and_o for_o the_o ambergris_n put_v therein_o i_o never_o know_v any_o woman_n trouble_v with_o the_o suffocation_n of_o the_o mother_n feel_v any_o manifest_a nuisance_n alteration_n or_o offence_n thereby_o ●s_v some_o imagine_v but_o if_o any_o man_n doubt_v thereof_o let_v he_o but_o only_o touch_v the_o pill_n intend_v ●o_o be_v give_v upon_o such_o occasion_n with_o a_o little_a ●yle_a of_o charabe_n or_o amber_n these_o be_v the_o laudanum_n or_o opiate_a composition_n which_o i_o have_v be_v content_v to_o describe_v in_o this_o book_n which_o indeed_o be_v all_o ●ery_a good_a and_o excellent_a in_o their_o operation_n although_o they_o differ_v something_o one_o from_o another_o in_o composition_n and_o diversity_n of_o ingredience_n yet_o the_o principal_a base_a common_a to_o they_o all_o be_v mere_o opium_n the_o reason_n why_o i_o ●ave_n not_o set_v down_o the_o preparation_n of_o this_o medicine_n in_o so_o ample_a and_o plain_a a_o manner_n and_o form_n as_o every_o particular_a reader_n may_v desire_v to_o make_v himself_o master_n of_o the_o mystery_n be_v in_o regard_n i_o will_v not_o wrong_v any_o private_a person_n who_o by_o his_o great_a ●abour_n cost_n and_o industry_n have_v purchase_v and_o get_v a_o more_o peculiar_a interest_n therein_o as_o have_v sufficient_a understanding_n knowledge_n and_o experience_n in_o the_o whole_a art_n of_o physic_n for_o although_o i_o be_o willing_a to_o make_v every_o man_n that_o shall_v read_v this_o treatise_n acquaint_v with_o the_o utility_n and_o profit_n which_o may_v redound_v and_o accrue_v by_o the_o use_n of_o such_o a_o medicine_n yet_o be_v it_o not_o my_o intention_n for_o all_o that_o to_o give_v occasion_n to_o many_o presumptuous_a person_n which_o rash_o and_o without_o any_o true_a ground_n other_o than_o their_o own_o private_a gain●_n make_v practice_n in_o physic_n will_v take_v in_o hand_n with_o a_o thing_n of_o so_o great_a consideration_n and_o importance_n as_o laudanum_n be_v and_o this_o be_v the_o reason_n also_o wherefore_o i_o do_v so_o free_o admonish_v and_o counsel_v every_o one_o that_o love_v his_o own_o life_n or_o the_o preservation_n of_o his_o health_n more_o than_o the_o spare_v of_o a_o sew_v scald_a penny_n not_o to_o take_v this_o medicine_n for_o any_o inward_a use_n at_o any_o man_n hand_n but_o only_o of_o such_o as_o have_v good_a knowledge_n therein_o and_o will_v faithful_o communicate_v the_o same_o not_o give_v quid_fw-la for_o quo_fw-la as_o some_o unworthy_a mercenary_n do_v who_o common_o gape_v after_o their_o own_o benefit_n and_o commodite_n rather_o than_o the_o good_a and_o safety_n of_o their_o sick_a patient_n furthermore_o i_o be_o not_o ignorant_a though_o a_o man_n may_v find_v many_o spagirist_n vaunt_v and_o brag_v they_o have_v this_o and_o that_o la●danum_n and_o other_o excellent_a anodynes_n compose_v without_o any_o opium_n at_o all_o some_o say_n they_o can_v make_v laudanum_n with_o mixtion_n only_o of_o certain_a cordial_n other_o will_v make_v the_o world_n believe_v they_o have_v a_o certain_a embrionated_a sulphur_n of_o vitrial_a which_o be_v a_o most_o rare_a precious_a medicine_n and_o somniferous_a anodyne_n but_o these_o be_v nothing_o but_o vain_a ostentation_n see_v that_o without_o opium_n or_o some_o other_o thing_n of_o equivalent_a and_o semblable_a faculty_n it_o be_v impossible_a for_o ●ny_n man_n to_o prepare_v any_o general_a true_a or_o certain_a anodyne_n how_o be_v it_o i_o deny_v not_o but_o by_o permixtion_n of_o certain_a thing_n differ_v one_o ●rom_o another_o in_o taste_n smell_v and_o quality_n a_o man_n may_v compose_v a_o handsome_a counterfeit_a laudanum_n see_v that_o i_o myself_o can_v prepare_v such_o a_o medicine_n of_o nutmeg_n mace_n myrrh_n saffron_n amber_n mask_n aqua-vita_a quintessence_n of_o sulphur_n etc._n etc._n without_o any_o opi●●_n the_o only_a smell_n whereof_o will_v provoke_v sleep_n and_o be_v administer_v will_v appease_v diverse_a grief_n yet_o for_o all_o that_o it_o be_v nothing_o so_o general_a or_o available_a a_o anodyne_n that_o it_o may_v be_v compare_v in_o any_o sort_n with_o that_o prepare_v of_o opium_n or_o if_o it_o be_v a_o man_n may_v doubtless_o make_v as_o great_a scruple_n to_o take_v that_o as_o the_o other_o for_o if_o opium_n can_v endanger_v the_o body_n by_o its_o natural_a somniferous_a quality_n why_o shall_v not_o another_o aromatical_a cordial_n do_v the_o same_o which_o by_o art_n have_v acquire_v the_o like_a faculty_n moreover_o concern_v the_o foresay_a sulphurous_a anodyne_n although_o paracelsus_n tell_v wonder_n of_o such_o a_o one_o in_o the_o seven_o chap._n of_o his_o book_n de_fw-fr re●_n nature_n wherein_o he_o discourse_v of_o diverse_a mineral_n sulphur_n it_o be_v so_o ingenious_o with_o crollius_n i_o confess_v that_o i_o never_o see_v any_o such_o medicine_n for_o have_v try●d_a conclusion_n and_o wrought_v long_a time_n upor_n vitriol_n i_o can_v never_o perceive_v it_o have_v any_o such_o substance_n in_o it_o which_o have_v like_o operation_n to_o that_o of_o opium_n as_o i_o have_v plain_o manifest_v in_o my_o book_n entitle_v anatomia_fw-la vitriol_n divulge_v five_o year_n since_o in_o regard_n whereof_o those_o be_v much_o deceive_v which_o by_o mean_n of_o its_o precipitation_n with_o salt_n of_o tartar_n by_o boil_v in_o a_o iron_n pot_n or_o by_o mean_n of_o sublimation_n do_v separate_v a_o greenish_a powder_n from_o vitriol_n call_v it_o sulphur_n ●mbryonatum_fw-la vitriol_n which_o be_v put_v to_o vulcan_n test_n a_o man_n may_v quick_o find_v it_o to_o be_v nothing_o but_o copper_n or_o be_v administer_v alter_v the_o stomach_n and_o rather_o provoke_v vomit_n than_o either_o comfort_n or_o disposition_n to_o sleep_v it_o be_v therefore_o apparent_a that_o paracelsus_n intend_v some_o other_o thing_n in_o this_o project_n than_o he_o vouchsafe_v to_o discover_v to_o us._n hence_o you_o may_v behold_v the_o reason_n wherefore_o we_o ought_v not_o to_o mis-prise_n and_o vilipend_v certain_a thing_n for_o uncertain_a but_o content_v ourselves_o with_o the_o aforesaid_a laudanum_n or_o such_o like_a with_o thanksgiving_n to_o the_o author_n of_o all_o goodness_n not_o suffer_v our_o understanding_n to_o be_v abuse_v by_o the_o vain_a flourish_n or_o idle_a fantasy_n of_o any_o other_o chap._n ix_o concern_v the_o virtue_n and_o use_n of_o all_o opiate_a laudanum_n aswell_o in_o general_a as_o particular_a have_v already_o set_v down_o the_o manner_n how_o to_o prep●●e_v opium_n well_o and_o to_o make_v excellent_a composition_n thereof_o call_v laudanum_n it_o behove_v we_o now_o to_o declare_v their_o virtue_n and_o use_n for_o the_o better_a direction_n and_o advertisement_n to_o they_o which_o shall_v have_v occasion_n to_o use_v the_o same_o the_o property_n of_o every_o laudanum_n which_o be_v well_o prepare_v and_o correct_v as_o beforesayd_a be_v principal_o six_o 1_o the_o first_o be_v to_o give_v ease_n or_o to_o cease_v all_o inward_a pain_n proceed_v of_o what_o cause_n soever_o and_o that_o at_o all_o time_n and_o to_o all_o person_n without_o exception_n of_o what_o complexion_n temprature_n age_n or_o constitution_n of_o body_n soever_o only_o have_v regard_n to_o the_o do_v and_o other_o circumstance_n which_o be_v requisite_a for_o the_o physician_n to_o observe_v 2_o to_o provoke_v those_o to_o sleep_v which_o be_v destitute_a thereof_o by_o reason_n of_o any_o corporal_a disease_n or_o alteration_n of_o spirit_n which_o thing_n it_o effect_v without_o dull_v or_o benumb_a the_o sense_n weaken_v the_o member_n constipate_v the_o body_n or_o produce_v any_o evil_a accident_n at_o all_o in_o they_o as_o other_o somniferous_a thing_n do_v which_o be_v natural_o cold_a and_o il_fw-mi prepare_v 3_o to_o stop_v all_o vehement_a subtle_a and_o corrode_a cathurrou_n distillation_n fall_v from_o the_o brain_n upon_o the_o low_a part_n thicken_a they_o by_o little_a and_o little_a strengthen_v the_o brain_n and_o repress_v the_o gross_a vapour_n which_o rise_v from_o the_o stomach_n upward_o which_o be_v ordinary_o the_o cause_n of_o such_o defluxion_n 4_o to_o stay_v natural_o the_o haemorrhagie_n dyssenterie_n and_o menstrual_a flux_n as_o also_o the_o dyarrhaea_n and_o flux_n of_o the_o belly_n proceed_v from_o the_o great_a distemperature_n of_o inward_a heat_n or_o some_o sharp_a and_o bite_a humour_n 5_o to_o consummate_v and_o cease_v all_o burn_a fever_n and_o praeternatural_a heat_n proceed_v from_o any_o wound_n or_o ulcer_n or_o from_o the_o fermentation_n or_o ripen_n of_o any_o choleric_a humour_n or_o any_o causticke_a or_o venomous_a matter_n 6_o to_o roborate_v and_o strengthen_v the_o bowel_n and_o all_o

of_o they_o in_o manner_n as_o follow_v the_o objection_n 1_o first_o that_o laudanum_n be_v principal_o compose_v of_o opium_n and_o still_o retain_v its_o somniferous_a property_n may_v consequent_o suffocate_v natural_a heat_n and_o benumb_v and_o stupefy_v all_o the_o sense_n 2_o see_v laudanum_n do_v incrassate_fw-it &_o thicken_v the_o subtle_a humour_n it_o follow_v that_o although_o it_o do_v cease_v pain_n for_o the_o time_n yet_o afterward_o it_o make_v the_o cause_n of_o the_o sickness_n malignant_a fix_v and_o incurable_a 3_o that_o it_o have_v be_v observe_v that_o some_o sick_a people_n have_v die_v some_o few_o hour_n after_o the_o take_n of_o laudanun_n inconsideration_n whereof_o we_o shall_v abstain_v from_o its_o use_n altogether_o the_o answer_n concern_v the_o first_o objection_n i_o be_o of_o opinion_n that_o if_o such_o man_n as_o go_v about_o to_o propose_v any_o such_o thing_n will_v either_o give_v place_n to_o the_o authority_n of_o great_a physician_n or_o experience-self_n both_o which_o assure_v we_o that_o c●ude_a opium_n take_v in_o small_a quantity_n neither_o suffocate_v natural_a hea●e_n nor_o dull_v the_o sense_n as_o have_v be_v already_o sufficient_o prove_v in_o the_o begin_n of_o this_o discourse_n they_o will_v neither_o blame_v nor_o so_o base_o esteem_v of_o it_o but_o suppose_v that_o a_o very_a small_a do_v of_o crude_a opium_n do_v produce_v such_o effect_n must_v it_o therefore_o do_v the_o same_o when_o it_o be_v deprive_v of_o the_o superfluity_n of_o its_o narcotical_a sulphur_n his_o acrimonie_n correct_v and_o after_o mix_v with_o such_o bezoardick_n and_o cordial_a thing_n as_o aforesaid_a no_o man_n of_o judgement_n or_o of_o any_o experience_n in_o the_o mystery_n of_o nature_n can_v deny_v that_o opium_n the_o principal_a ingredience_n or_o basis_n of_o laudanum_n be_v thus_o alter_v both_o in_o form_n and_o substance_n become_v likewise_o change_v in_o its_o virtue_n and_o operation_n and_o therefore_o can_v with_o no_o reason_n censure_v so_o hardly_o thereof_o as_o when_o it_o be_v crude_a and_o notwithstanding_o that_o laudanun_n do_v provoke_v the_o disease_a to_o sleep_v yet_o daily_a experience_n teach_v we_o that_o it_o do_v not_o suffocate_v natural_a heat_n but_o rather_o preserve_v it_o when_o it_o be_v about_o to_o consume_v and_o in_o danger_n to_o be_v sudden_o extinct_a by_o reason_n of_o its_o violent_a motion_n extreme_a pain_n and_o extraordinary_a watch_v whereby_o it_o be_v as_o rude_o handle_v as_o a_o lamp_n or_o burning-torch_n be_v in_o a_o mighty_a tempest_n which_o cause_v a_o great_a waste_n of_o oil_n and_o loss_n of_o light_n than_o it_o will_v do_v if_o it_o be_v defend_v from_o such_o a_o accident_n 2_o for_o the_o second_o objection_n laudanum_n be_v so_o far_o from_o aggravate_v impair_n or_o make_v worse_o the_o cause_n of_o the_o disease_n by_o reason_n of_o its_o incrassate_a faculty_n that_o quite_o contrary_a it_o prepare_v some_o offend_a humour_n and_o make_v they_o far_o more_o apt_a and_o easy_a to_o be_v expel_v as_o in_o the_o 21._o passage_n before_o concern_v gout_n we_o have_v something_o declare_v for_o be_v it_o not_o the_o consent_n and_o verdict_n of_o the_o best_a physician_n in_o the_o world_n that_o the_o preparation_n of_o humour_n before_o purgation_n do_v chief_o consist_v in_o two_o operation_n that_o be_v in_o subtilize_v and_o attenuate_v of_o those_o which_o be_v viscouse_n thick_a and_o clammy_a and_o incrassate_v and_o thicken_a indifferent_o those_o which_o be_v too_o subtle_a virulent_a windy_a &_o vagant_fw-la in_o the_o body_n now_o the_o great_a part_n of_o extreme_a pain_n and_o inward_a heat_n proceed_v from_o some_o dissolve_a matter_n that_o be_v either_o salt_n sharp_a or_o corrode_a or_o from_o such_o as_o do_v excoriate_v inflame_v and_o alter_v the_o member_n affect_v whereby_o malignant_a vapour_n arise_v which_o pass_v unto_o the_o adjoin_v part_n do_v by_o consent_n produce_v sundry_a torment_n &_o many_o evil_a accident_n as_o by_o experience_n be_v manifest_a what_o better_a course_n can_v a_o man_n observe_v then_o by_o mean_n of_o laudanum_n to_o thicken_v and_o digest_v the_o say_v humour_n &_o sequester_v &_o consume_v the_o aforesaid_a vapour_n in_o such_o sort_n that_o they_o can_v by_o no_o mean_n exercise_v their_o cruelty_n as_o before_o and_o in_o case_n of_o superfluity_n if_o it_o be_v any_o way_n requisite_a to_o be_v purge_v a_o man_n may_v do_v it_o afterward_o far_o more_o wary_o and_o safe_o then_o in_o the_o former_a estate_n be_v not_o this_o represent_v to_o any_o man_n understanding_n by_o sundry_a outward_a ulcer_n which_o be_v inflame_v and_o distil_a from_o some_o subtle_a and_o corrosive_n humour_n cause_n great_a prick_a dolour_n and_o pain_n and_o oftentimes_o by_o consent_n a_o fever_n to_o the_o patient_n so_o that_o the_o true_a remedy_n in_o such_o a_o case_n to_o take_v away_o such_o accident_n be_v some_o excellent_a anodyne_n which_o may_v mitigate_v and_o assuage_v that_o unnatural_a heat_n and_o sudden_o ripen_v and_o indifferent_o thicken_v the_o offend_a humour_n which_o be_v so_o subtle_a and_o corrosive_n which_o be_v do_v all_o other_o symptom_n cease_v whatsoever_o laudanum_n then_o not_o only_o produce_v these_o effect_n by_o its_o natural_a property_n but_o also_o mundify_v resist_a putrefaction_n and_o heal_v and_o comfort_v the_o weaken_a part_n as_o it_o be_v balsam_n may_v by_o good_a consequence_n take_v away_o or_o extinguish_v the_o cause_n of_o many_o evil_a symptom_n rather_o than_o impair_v and_o make_v they_o incurable_a for_o although_o it_o do_v moderate_o incrassate_fw-it yet_o notwithstanding_o it_o do_v not_o coagulate_v the_o blood_n nor_o fix_v the_o substance_n which_o in_o their_o own_o proper_a nature_n be_v liquid_a in_o stone_n nor_o solder_v or_o glue_v the_o part_n together_o as_o gypsum_fw-la do_v for_o which_o cause_n only_a man_n shall_v blame_v it_o in_o such_o manner_n as_o before_o 3_o three_o we_o will_v not_o deny_v but_o that_o some_o sick_a person_n may_v chance_v to_o die_v soon_o after_o the_o receipt_n of_o laudanum_n but_o that_o laudanum_n be_v the_o cause_n of_o their_o death_n &_o that_o in_o regard_n thereof_o its_o use_n be_v utter_o to_o be_v abandon_v and_o forsake_v be_v the_o matter_n now_o in_o question_n first_o therefore_o it_o be_v very_o apparent_a by_o our_o former_a discourse_n that_o laudanum_n be_v not_o a_o thing_n of_o such_o a_o venomous_a quality_n as_o will_v cause_v death_n to_o the_o receiver_n for_o albeit_o the_o observation_n be_v true_a that_o some_o have_v die_v soon_o after_o the_o take_n thereof_o yet_o that_o ought_v not_o to_o supersede_n all_o other_o reason_n attestation_n &_o experience_n concern_v the_o good_a effect_n and_o safe_a use_n of_o laudanum_n for_o as_o it_o be_v a_o absurd_a and_o foolish_a thing_n for_o a_o man_n to_o say_v ●_o do_v see_v certain_a grain_n of_o bezoar-stone_n vnicornes-horne_n pearl_n or_o such_o like_a precious_a cordial_n give_v to_o a_o sick_a person_n who_o die_v not_o long_o after_o ergo_fw-la that_o be_v the_o cause_n of_o his_o death_n and_o therefore_o take_v heed_n of_o use_v any_o such_o thing_n hereafter_o or_o i_o see_v one_o give_v a_o clyster_n to_o such_o a_o sick_a person_n who_o die_v soon_o after_o ergo_fw-la clyster_n be_v dangerous_a remedy_n and_o ought_v not_o to_o be_v use_v as_o many_o simple_a people_n be_v accustom_v to_o argue_v even_o so_o it_o be_v as_o absurd_a a_o thing_n to_o hold_v laudanum_n in_o suspicion_n because_o such_o a_o one_o take_v it_o &_o after_o dy●d_v for_o although_o it_o do_v principal_o and_o speedy_o cause_v all_o torment_n to_o cease_v and_o provoke_v the_o disease_a to_o sleep_v yet_o that_o be_v no_o consequence_n that_o it_o can_v preserve_v a_o man_n from_o death_n when_o by_o god_n his_o secret_a decree_n his_o hour_n be_v come_v for_o neither_o that_o nor_o no_o other_o medicine_n in_o the_o world_n can_v do_v sleep_n and_o exemption_n from_o pain_n be_v necessary_a thing_n as_o well_o for_o sound_v as_o sick_a man_n the_o one_o with_o distinction_n the_o other_o without_o all_o exception_n but_o that_o these_o two_o do_v sometime_o serve_v for_o the_o maintenance_n and_o strengthen_n of_o man_n life_n and_o other_o sometime_o be_v unnecessary_a and_o of_o no_o use_n this_o proceed_v not_o through_o any_o fault_n in_o themselves_o but_o in_o nature_n which_o do_v not_o receive_v they_o for_o her_o own_o good_a and_o benefit_n as_o other_o time_n she_o use_v to_o do_v which_o thing_n be_v lively_o represent_v unto_o we_o by_o the_o use_n of_o meat_n drink_n and_o all_o other_o thing_n call_v medicine_n not_o natural_a which_o sometime_o be_v good_a and_o profitable_a to_o the_o body_n and_o sometime_o quite_o contrary_a even_o as_o nature_n dispose_v of_o they_o for_o our_o good_a or_o evil_a howsoever_o in_o themselves_o they_o