let_v we_o next_o inquire_v how_o it_o do_v enter_v human_a body_n and_o there_o be_v four_o way_n by_o which_o it_o be_v common_o believe_v the_o air_n may_v enter_v they_o either_o first_o by_o its_o mix_v its_o self_n with_o what_o we_o eat_v and_o so_o be_v carry_v to_o the_o stomach_n or_o second_o it_o be_v receive_v by_o inspiration_n into_o the_o lung_n and_o so_o be_v carry_v to_o the_o heart_n or._n three_o by_o the_o pore_n of_o the_o body_n and_o from_o thence_o to_o the_o mass_n of_o blood_n or_o last_o in_o inspiration_n to_o the_o ventricles_n of_o the_o brain_n the_o two_o first_o of_o which_o i_o think_v be_v only_o true_a as_o to_o the_o first_o i_o think_v it_o be_v undoubted_o true_a that_o the_o air_n do_v or_o aereal_a particle_n do_v mix_v themselves_o with_o what_o we_o eat_v for_o whatever_o we_o eat_v must_v have_v numerous_a pore_n or_o else_o we_o can_v never_o chew_v it_o with_o out_o tooth_n nor_o digest_v it_o in_o our_o stomach_n or_o separate_v chyle_n from_o it_o and_o i_o believe_v the_o air_n may_v sometime_o enter_v these_o pore_n however_o it_o do_v enter_v the_o mouth_n and_o be_v press_v down_o the_o oesophagus_n either_o by_o the_o aliment_n or_o force_v of_o the_o aereal_a atom_n natural_o descend_v downward_o second_o it_o be_v apparent_a both_o by_o dissection_n and_o inflation_n of_o the_o lung_n that_o the_o air_n do_v enter_v from_o the_o larnix_n and_o bronchia_fw-la into_o the_o vesiculary_a cell_n and_o there_o whether_o by_o adhesion_n of_o dissolution_n do_v deposit_v at_o least_o some_o part_n of_o this_o aereal_a salt_n where_o meet_v with_o the_o occur_v humour_n be_v direct_o carry_v to_o the_o heart_n and_o by_o its_o pungent_a particle_n molest_v and_o irritate_v the_o straight_a and_o oblique_a fibre_n of_o the_o heart_n do_v stir_v they_o up_o into_o a_o systole_n or_o contraction_n and_o so_o by_o streightning_n its_o ventricles_n to_o drive_v forth_o the_o blood_n contain_v in_o they_o into_o the_o artery_n and_o this_o i_o take_v to_o be_v the_o true_a original_a of_o all_o pulsation_n and_o first_o motion_n of_o the_o heart_n and_o circulation_n of_o the_o blood_n throughout_o the_o body_n for_o when_o i_o observe_v the_o motion_n of_o the_o heart_n of_o several_a creature_n exempt_a from_o their_o body_n and_o expose_v to_o the_o open_a air_n i_o can_v never_o believe_v either_o the_o influx_n of_o animal_n spirit_n much_o less_o the_o ebullition_n accension_n or_o dilatation_n of_o the_o heart_n to_o be_v the_o cause_n of_o its_o motion_n but_o rather_o the_o effect_n of_o these_o pungent_a particle_n prick_v upon_o the_o fibrous_a parenchyma_n of_o the_o heart_n in_o their_o natural_a descend_v motion_n as_o to_o the_o other_o two_o way_n of_o receive_v air_n viz._n by_o the_o pore_n of_o the_o body_n when_o i_o consider_v the_o nature_n of_o these_o atom_n press_v direct_o downward_o when_o i_o consider_v the_o great_a quantity_n of_o effluvia_fw-la that_o be_v continual_o transpire_v by_o the_o cuticulary_a pore_n when_o i_o consider_v the_o nature_n of_o those_o pore_n and_o their_o action_n to_o be_v continue_v suitable_a to_o the_o utmost_a extremity_n of_o the_o artery_n from_o whence_o they_o original_o be_v derive_v i_o can_v see_v how_o the_o air_n can_v enter_v without_o either_o penetratione_fw-la corporum_fw-la or_o a_o inversion_n of_o nature_n constant_a course_n à _fw-la centro_fw-la ad_fw-la circumferentiam_fw-la corporis_fw-la the_o argument_n that_o be_v bring_v to_o prove_v the_o porosity_n of_o animal_n by_o the_o take_n in_o of_o effluvia_fw-la from_o without_o by_o the_o application_n of_o oil_n and_o plaster_n if_o right_o consider_v make_v nothing_o to_o this_o purpose_n to_o prove_v the_o entrance_n of_o this_o aereal_a salt_n by_o the_o cuticulary_a pore_n for_o set_v aside_o a_o particular_a enquiry_n into_o the_o nature_n of_o those_o plaster_n their_o subtle_a active_a igneous_a violent_a cool_a dry_a irritate_v stupify_a obstruct_v and_o preternatural_o dispose_v particle_n the_o cuticulary_a pore_n be_v not_o place_v for_o the_o due_a reception_n of_o this_o salt_n nor_o have_v the_o point_n of_o this_o salt_n a_o force_n upon_o they_o since_o they_o natural_o descend_v perpendicular_o downward_o neither_o when_o i_o observe_v the_o difference_n between_o the_o florid_n aereal_a colour_a blood_n return_v from_o the_o lung_n and_o the_o atropurpureal_a blood_n contain_v in_o the_o vein_n can_v i_o believe_v this_o aereal_a salt_n do_v enter_v by_o the_o pore_n or_o be_v mix_v with_o the_o venal_a blood_n when_o i_o see_v the_o venal_a blood_n both_o change_v in_o colour_n and_o consistence_n from_o what_o i_o either_o find_v in_o the_o lung_n or_o artery_n and_o as_o to_o the_o last_o of_o these_o way_n when_o the_o author_n acquaint_v we_o how_o the_o particle_n of_o air_n be_v part_v asunder_o in_o inspiration_n part_n of_o they_o ascend_v by_o the_o mammillary_n processes_n ad_fw-la cerebri_fw-la vasa_n &_o ventriculos_fw-la and_o part_n descend_v to_o the_o pulmonary_a vessel_n when_o they_o can_v i_o say_v explicate_v with_o any_o great_a probability_n how_o this_o be_v do_v for_o what_o end_n or_o use_v the_o air_n thus_o impregnate_v with_o this_o salt_n shall_v come_v thither_o it_o will_v deserve_v further_a consideration_n for_o although_o the_o mammillary_n process_n may_v be_v affect_v by_o the_o point_n of_o this_o salt_n and_o according_a to_o the_o various_a and_o different_a modification_n of_o they_o so_o various_a and_o different_a smell_n may_v be_v convey_v unto_o the_o brain_n nay_o although_o the_o particle_n of_o this_o salt_n be_v very_o different_a as_o to_o their_o shape_n and_o bigness_n size_n and_o figure_n yet_o do_v i_o not_o see_v how_o nor_o for_o what_o end_n or_o use_v by_o these_o nervous_a process_n they_o shall_v ever_o be_v convey_v neither_o can_v i_o see_v how_o these_o nerve_n or_o even_o the_o brain_n itself_o shall_v escape_v a_o strong_a vellication_n by_o they_o which_o be_v communicate_v by_o the_o nerve_n may_v cause_v a_o convulsive_a motion_n in_o every_o member_n in_o the_o body_n chap._n iu._n now_o as_o i_o have_v own_v but_o only_o two_o way_n by_o which_o this_o aereal_a salt_n can_v be_v receive_v into_o human_a body_n so_o do_v i_o very_o much_o question_n whether_o any_o thing_n else_o be_v leave_v in_o a_o healthy_a air_n to_o join_v either_o with_o chyle_n or_o blood_n but_o this_o aereal_a modify_v salt_n only_o which_o of_o its_o self_n be_v able_a to_o produce_v these_o great_a and_o follow_a effect_n first_o this_o salt_n as_o it_o be_v various_o mix_v or_o modify_v by_o the_o aliment_n we_o take_v into_o our_o mouth_n so_o different_a taste_n appear_v unto_o we_o and_o either_o descend_v or_o press_v down_o by_o other_o particle_n cause_n that_o disturb_a vellication_n on_o the_o inner_a membrane_n of_o the_o nerve_n that_o seem_v as_o it_o be_v place_v there_o on_o purpose_n to_o communicate_v that_o vellication_n to_o the_o brain_n do_v occasion_n that_o desire_n in_o we_o which_o we_o call_v hunger_n and_o from_o hence_o the_o take_v the_o fresh_a air_n do_v make_v we_o hungry_a because_o we_o then_o receive_v this_o aereal_a salt_n both_o into_o our_o lung_n and_o stomach_n but_o it_o be_v not_o the_o fibre_n of_o the_o upper_a orifice_n alone_o but_o descend_v to_o the_o bottom_n of_o the_o stomach_n with_o the_o aliment_n or_o what_o we_o eat_v it_o have_v the_o same_o operation_n on_o the_o other_o fibres_fw-fr and_o move_v they_o to_o eject_v out_o at_o the_o pylorus_n and_o irritate_v all_o along_o on_o the_o fibre_n of_o the_o intestine_n be_v a_o great_a cause_n of_o and_o a_o considerable_a advantage_n to_o their_o peristaltic_a motion_n but_o though_o this_o salt_n be_v so_o high_o useful_a to_o the_o motion_n of_o the_o stomach_n yet_o the_o stomachical_a operation_n be_v not_o perform_v by_o it_o alone_o for_o i_o have_v observe_v near_o the_o rugae_fw-la of_o great_a animal_n certain_a papillae_fw-la and_o a_o constant_a juice_n lodge_v in_o they_o which_o i_o believe_v to_o be_v a_o acid_n lympha_fw-la bring_v thither_o by_o invisible_a lymphatic_a vessel_n which_o we_o have_v great_a reason_n to_o believe_v do_v moisten_v the_o fibrous_a tunicle_n of_o the_o ventricles_n although_o they_o be_v not_o perceptible_a to_o our_o sight_n i_o know_v i_o may_v have_v trace_v the_o generation_n of_o animal_n and_o have_v show_v not_o only_o how_o the_o prima_fw-la stamina_fw-la aquavitae_fw-la the_o motion_n of_o the_o punctum_fw-la saliens_fw-la nay_o even_o the_o birth_n itself_o be_v owe_v to_o this_o salt_n as_o likewise_o i_o may_v show_v the_o effect_n of_o different_a occur_v salt_n that_o meet_v together_o in_o the_o duodenum_fw-la but_o design_v brevity_n i_o must_v hasten_v next_o to_o show_v what_o great_a effect_n this_o nitrous_a salt_n do_v common_o produce_v upon_o our_o
a_fw-la enquiry_n into_o the_o cause_n of_o disease_n in_o general_z and_o the_o disturbance_n of_o the_o humour_n in_o man_n body_n wherein_o the_o nature_n of_o the_o blood_n of_o the_o air_n and_o of_o a_o pestilential_a constitution_n be_v brief_o consider_v together_o with_o some_o observation_n show_v wherein_o the_o venom_n of_o viper_n particular_o that_o of_o the_o english_a adder_n do_v consist_v by_o stanford_n wolferstan_n m._n a._n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d hypocrates_n lib._n de_fw-la flatibus_fw-la london_n print_v for_o thomas_n basset_n at_o the_o george_n in_o fleetstreet_n 1692._o to_o the_o right_n honourable_a francis_n l_o d._n carrington_n baron_n of_o wotton_n viscount_n berrisfore_o in_o the_o kingdom_n of_o ireland_n my_o lord_n there_o be_v two_o thing_n the_o world_n may_v perhaps_o wonder_v at_o first_o my_o confidence_n in_o divulge_v my_o own_o opinion_n after_o so_o many_o great_a man_n in_o so_o learned_a a_o age._n and_o second_o my_o presume_v to_o present_v they_o to_o so_o honourable_a a_o person_n in_o answer_n to_o the_o first_o i_o must_v needs_o say_v that_o the_o dissatisfaction_n i_o have_v meet_v withal_o in_o book_n as_o to_o most_o of_o these_o thing_n make_v i_o resolve_v to_o speak_v my_o own_o thought_n and_o as_o to_o the_o second_o your_o lordship_n be_v great_a judgement_n in_o these_o study_n and_o regard_v for_o they_o late_o honour_v the_o faculty_n with_o encourage_v so_o near_o and_o worthy_a a_o relation_n of_o your_o own_o in_o these_o study_n together_o with_o your_o lordship_n condescend_v attention_n and_o favourable_a regard_n to_o my_o weak_a discourse_n sometime_o on_o such_o subject_n these_o thing_n my_o lord_n have_v embolden_v i_o to_o present_v these_o physiological_a inquiry_n which_o i_o offer_v with_o a_o very_a grateful_a acknowledgement_n of_o your_o lordship_n condescend_v favour_n to_o my_o lord_n your_o lordship_n be_v most_o obedient_a humble_a servant_n stanford_n wolferstan_n the_o preface_n notwithstanding_o the_o voluminous_a author_n that_o we_o have_v in_o physic_n both_o greek_n arabian_n and_o latter_a commentator_n physic_n till_o of_o late_a since_o the_o day_n of_o hypocrates_n have_v receive_v but_o small_a improvement_n for_o if_o the_o circulation_n of_o the_o blood_n on_o which_o both_o the_o theory_n and_o practice_n of_o physic_n ought_v to_o be_v build_v be_v discover_v by_o solomon_n enigmatical_o by_o a_o wheel_n he_o be_v never_o till_o of_o late_o understand_v if_o andreas_n caesalpinus_n know_v any_o thing_n of_o it_o that_o knowledge_n till_o of_o late_o be_v never_o improve_v no_o method_n of_o practice_n be_v build_v on_o it_o the_o present_a state_n of_o the_o art_n of_o physic_n be_v just_a like_o that_o of_o war_n both_o have_v receive_v considerable_a improvement_n the_o one_o to_o save_v and_o the_o other_o to_o destroy_v mankind_n the_o practical_a part_n of_o physic_n without_o the_o theory_n be_v like_o downright_o fight_v without_o the_o wisdom_n and_o conduct_n of_o general_n officer_n and_o we_o see_v more_o town_n take_v and_o country_n overrun_v by_o the_o prudent_a conduct_n of_o commander_n than_o either_o by_o the_o use_n of_o gun_n or_o pike_n the_o practice_n of_o physic_n without_o the_o theory_n be_v just_a like_o a_o great_a house_n build_v without_o foundation_n which_o however_o it_o may_v appear_v fair_a at_o first_o unto_o the_o eye_n of_o the_o beholder_n will_v quick_o tumble_v into_o ruin_n and_o disorder_n for_o as_o i_o remember_v a_o eminent_a physician_n have_v late_o tell_v we_o harris_n dr._n walt._n harris_n if_o the_o art_n of_o physic_n do_v consist_v only_o in_o tell_v medicine_n or_o write_v receipt_n the_o apothecary_n will_v excel_v the_o most_o learned_a physician_n the_o prate_a shop-boy_n his_o master_n a_o nurse_n or_o talkative_a woman_n full_a of_o her_o antiquate_a book-receipt_n will_v carry_v the_o prize_n and_o glory_n from_o they_o all_o whereas_o if_o the_o true_a theory_n of_o disease_n be_v first_o well_o know_v few_o medicine_n will_v serve_v turn_n and_o practice_n will_v be_v much_o more_o successful_a than_o general_o it_o be_v i_o have_v here_o only_o show_v what_o give_v the_o first_o disturbance_n unto_o the_o humour_n of_o our_o body_n the_o next_o enquiry_n will_v be_v what_o humour_n be_v the_o first_o disturb_v the_o manner_n of_o their_o disturbance_n the_o effect_n of_o and_o remedy_n to_o each_o particular_a disorder_n and_o if_o the_o success_n be_v answerable_a to_o the_o hypothesis_n than_o it_o will_v appear_v that_o the_o theory_n of_o physic_n be_v a_o most_o necessary_a part_n of_o that_o study_n i_o must_v confess_v i_o have_v lay_v aside_o my_o book_n in_o these_o physiological_a inquiry_n to_o speak_v my_o own_o thought_n so_o that_o if_o the_o reader_n find_v here_o any_o opinion_n contrary_a to_o his_o own_o or_o his_o belove_a author_n let_v he_o not_o too_o much_o blame_v i_o for_o it_o there_o be_v a_o libertas_n philosophica_fw-la as_o well_o as_o a_o licentia_fw-la poetica_fw-la which_o liberty_n i_o hope_v i_o have_v no_o way_n abuse_v if_o he_o reap_v any_o benefit_n or_o satisfaction_n from_o it_o he_o be_v partly_o oblige_v to_o that_o great_a and_o general_a want_n or_o defect_n that_o first_o occasion_v it_o for_o which_o you_o may_v take_v the_o word_n of_o our_o learned_a professor_n dr._n brady_n in_o his_o epistle_n to_o dr._n sydenham_n nemo_fw-la uspiam_fw-la medicorum_fw-la adhuc_fw-la vim_o aeris_fw-la &_o influentiam_fw-la in_o humana_fw-la corpora_fw-la attente_fw-la perpendit_fw-la nec_fw-la in_o vita_fw-la nostra_fw-la perennanda_fw-la quas_fw-la agit_fw-fr part_n eorum_fw-la quispiam_fw-la consideravit_fw-la satis_fw-la etc._n etc._n a_o enquiry_n into_o the_o cause_n of_o disease_n in_o general_a etc._n etc._n chapter_n i._n former_a physician_n be_v wont_v diligent_o to_o inquire_v what_o solid_a part_n in_o their_o sick_a patient_n be_v ill-affected_a and_o to_o look_v for_o the_o cause_n of_o a_o disease_n either_o into_o the_o solid_a part_n they_o find_v so_o ill-disposed_a or_o the_o four_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d humidi_fw-la formas_fw-la vel_fw-la species_n as_o hypocrates_n call_v they_o hae_fw-la vero_fw-la sunt_fw-la as_o it_o follow_v pituita_fw-la sanguis_fw-la bilis_fw-la &_o aqua_fw-la whereas_o indeed_o there_o be_v but_o one_o of_o these_o humour_n corporis_fw-la in_o a_o true_a sense_n which_o be_v the_o blood_n itself_o the_o other_o three_o be_v only_o the_o recrement_n of_o that_o blood_n no_o wonder_n then_o that_o the_o ancient_n be_v mistake_v in_o the_o true_a cause_n and_o right_a name_n of_o disease_n since_o they_o do_v not_o well_o inquire_v into_o the_o nature_n of_o the_o blood_n and_o be_v indeed_o very_o ignorant_a of_o many_o humour_n in_o the_o body_n but_o our_o modern_a physician_n find_v this_o error_n especial_o since_o the_o day_n of_o dr._n harvey_n have_v both_o chimical_o anatomize_v the_o blood_n and_o other_o humour_n of_o our_o body_n and_o diligent_o endeavour_v to_o observe_v their_o nature_n variation_n alienation_n and_o effect_n they_o more_o just_o seem_v to_o find_v the_o immediate_a cause_n of_o many_o distemper_n in_o the_o humour_n who_o in_o their_o wander_a motion_n about_o the_o body_n do_v disaffect_v and_o disturb_v the_o solid_a part_n which_o else_o before_o be_v very_a sound_n and_o quiet_a from_o hence_o in_o the_o write_n of_o the_o modern_n we_o find_v new_a disease_n new_a cause_n and_o new_a name_n according_a to_o the_o various_a ill_a disposition_n alienation_n or_o suppose_a ill_a fermentation_n of_o those_o humour_n but_o what_o give_v disturbance_n first_o unto_o those_o humour_n be_v now_o become_v the_o grand_a question_n among_o learned_a men._n some_o believe_v the_o cause_n to_o be_v in_o the_o humour_n themselves_o and_o as_o the_o ancient_a physician_n very_o often_o place_v the_o cause_n of_o a_o disease_n in_o the_o solid_a part_n so_o now_o we_o have_v the_o morbi_fw-la salivae_fw-la morbi_fw-la chyli_n succi_n pancreatici_n lymphae_fw-la etc._n etc._n and_o yet_o the_o several_a humour_n be_v so_o fit_v for_o each_o other_o service_n and_o the_o great_a end_n they_o be_v design_v for_o they_o so_o regular_o perform_v their_o office_n and_o be_v so_o well_o prepare_v for_o one_o another_o that_o we_o may_v rather_o wonder_v we_o live_v not_o the_o age_n of_o the_o patriarch_n than_o that_o we_o be_v so_o often_o disturb_v by_o any_o intestine_a war_n among_o they_o for_o if_o the_o mouth_n receive_v nothing_o but_o what_o be_v fit_a as_o to_o the_o nature_n and_o quality_n of_o the_o aliment_n if_o it_o exceed_v not_o in_o quantity_n if_o it_o stay_v there_o its_o just_a time_n mastication_n be_v perform_v regular_o the_o saliva_n will_v mix_v with_o it_o and_o the_o stomach_n will_v perform_v its_o office_n in_o the_o maceration_n digestion_n and_o expulsion_n of_o it_o the_o pancreatic_a juice_n lympha_fw-la etc._n etc._n be_v fit_v for_o their_o several_a duty_n of_o separation_n
attenuation_n and_o dilution_n of_o the_o chyle_n without_o any_o preternatural_a commotion_n to_o disorder_v or_o disturb_v one_o another_o nor_o do_v the_o blood_n quarrel_n with_o the_o well_o prepare_v chyle_n but_o amicable_o receive_v it_o from_o the_o ductus_fw-la thoracicus_n into_o the_o subclavian_n vein_n and_o as_o amicable_o pass_v with_o it_o into_o the_o right_a ventricle_n of_o the_o heart_n where_o though_o in_o the_o diastole_n they_o be_v more_o mix_v together_o yet_o they_o stay_v not_o to_o make_v that_o bustle_v some_o have_v think_v but_o by_o the_o systole_n or_o contraction_n of_o the_o heart_n be_v soon_o drive_v out_o again_o the_o chyle_n accompany_v the_o blood_n to_o the_o great_a among_o all_o the_o viscera_n for_o sanguification_n i_o mean_v the_o lung_n where_o they_o both_o receive_v a_o florid_n red_a and_o by_o the_o admission_n of_o new_a particle_n be_v more_o perfect_o assimulate_v or_o unite_v with_o each_o other_o so_o that_o even_o in_o fever_n which_o seem_v to_o give_v the_o great_a disturbance_n to_o the_o humour_n of_o our_o body_n the_o disturbance_n do_v not_o first_o arise_v from_o a_o quarrel_n raise_v among_o the_o humour_n of_o our_o body_n for_o as_o long_o as_o no_o strange_a ill_a guest_n come_v in_o to_o disturb_v they_o they_o all_o perform_v their_o natural_a office_n in_o their_o wont_a order_n but_o if_o they_o be_v hinder_v or_o disturb_v in_o their_o operation_n by_o a_o enemy_n they_o then_o fall_v into_o tumult_n and_o disorder_n the_o blood_n do_v not_o quarrel_n with_o its_o self_n nor_o one_o part_n of_o it_o with_o another_o for_o real_o there_o be_v no_o fermentation_n true_o and_o proper_o so_o call_v in_o it_o neither_o according_a to_o the_o suppose_a fermentation_n do_v one_o part_n act_n upon_o or_o against_o another_o for_o i_o consider_v the_o blood_n not_o as_o it_o be_v chemical_o analyze_v into_o their_o principle_n but_o as_o it_o be_v a_o viscous_a humour_n who_o particle_n be_v not_o ferment_v but_o combine_v together_o by_o a_o aereal_a salt_n receive_v heat_n from_o its_o own_o motion_n and_o circulation_n round_o the_o body_n who_o recrement_n be_v separate_v from_o it_o by_o the_o various_a and_o admirable_a contexture_n and_o configuration_n of_o the_o vessel_n through_o which_o they_o pass_v whilst_o the_o viscid_a humour_n or_o thick_a part_n of_o the_o blood_n keep_v close_a and_o entire_a and_o by_o the_o anastomase_n which_o i_o suppose_v whether_o visible_a or_o not_o of_o the_o vein_n and_o artery_n be_v bring_v back_o to_o the_o heart_n a_o languid_a pulse_n be_v continue_v by_o the_o extremity_n of_o the_o artery_n to_o every_o vessel_n which_o help_v forward_o the_o separation_n secretion_n percolation_n or_o which_o you_o shall_v please_v to_o call_v it_o of_o the_o thin_a humour_n i_o shall_v not_o stay_v here_o further_o to_o show_v either_o the_o incapacity_n of_o the_o blood_n or_o unfitness_n of_o the_o vessel_n through_o which_o it_o pass_v nor_o the_o danger_n of_o such_o heterogeneous_a ferment_a liquor_n especial_o near_o the_o extremity_n of_o such_o small_a fine_a and_o thin_a vessel_n through_o which_o these_o liquor_n of_o such_o different_a ferment_a particle_n must_v violent_o pass_v neither_o shall_v i_o show_v how_o the_o viper_n and_o several_a other_o animal_n that_o sleep_v all_o winter_n who_o blood_n be_v not_o deny_v to_o circulate_v all_o that_o while_n neither_o void_a any_o excrement_n all_o that_o while_n nor_o be_v their_o bladder_n of_o gall_n full_a when_o they_o first_o come_v forth_o in_o the_o spring_n than_o when_o in_o winter_n they_o first_o take_v their_o bed_n to_o demonstrate_v that_o either_o the_o blood_n do_v not_o always_o ferment_n or_o that_o the_o gall_n be_v not_o throw_v off_o by_o such_o a_o fermentation_n so_o that_o as_o i_o can_v believe_v disease_n with_o the_o ancient_n so_o often_o to_o arise_v from_o the_o solid_a part_n nor_o the_o blood_n to_o consist_v of_o their_o four_o humour_n neither_o can_v i_o believe_v such_o a_o bustle_n keep_v in_o our_o body_n as_o have_v of_o late_o be_v talk_v of_o i_o neither_o believe_v the_o solid_a part_n nor_o humour_n of_o our_o body_n to_o conspire_v our_o ruin_n chap._n ii_o so_o that_o whatever_o commotion_n fermentation_n ebullition_n or_o disturbance_n there_o be_v raise_v in_o the_o blood_n or_o humour_n must_v arise_v preternatural_o and_o ab_fw-la extra_fw-la for_o else_o neither_o blood_n nor_o humour_n will_v of_o themselves_o raise_v such_o violent_a commontion_n or_o disturbance_n in_o man_n body_n it_o be_v unquestionable_o true_a that_o the_o air_n above_o all_o the_o other_o non-naturals_a be_v the_o great_a cause_n of_o our_o epidemic_a fever_n the_o best_a way_n therefore_o to_o know_v the_o nature_n of_o such_o fever_n next_o to_o the_o knowledge_n of_o the_o blood_n will_v be_v to_o consider_v the_o nature_n of_o the_o air_n we_o breath_n in_o i_o shall_v not_o enlarge_v here_o concern_v the_o various_a opinion_n of_o philosopher_n concern_v the_o nature_n of_o air_n neither_o shall_v i_o determine_v from_o whence_o it_o do_v arise_v or_o of_o what_o compose_v it_o be_v two_o large_a discourse_n for_o my_o present_a purpose_n but_o i_o shall_v only_o suppose_v the_o air_n to_o be_v a_o very_a thin_a and_o fluid_a body_n combine_v most_o strict_o with_o a_o nitrous_a salt_n and_o by_o the_o pressure_n of_o other_o particle_n together_o with_o its_o own_o natural_a fineness_n and_o subtlety_n pervade_v every_o patulous_a poor_a in_o earth_n and_o water_n i_o say_v patulous_a because_o i_o deny_v not_o nay_o i_o affirm_v there_o be_v many_o pore_n especial_o in_o the_o earth_n which_o the_o aereal_a particle_n be_v not_o fine_a enough_o to_o enter_v and_o indeed_o both_o earth_n and_o water_n do_v resist_v its_o penetration_n but_o not_o with_o equal_a force_n for_o the_o air_n can_v enter_v very_o far_o into_o the_o more_o strict_o unite_v and_o combine_v particle_n of_o earth_n but_o the_o grosser_n part_n of_o the_o aereal_a salt_n be_v necessitate_v to_o stick_v fast_o from_o whence_o with_o easy_a trouble_n we_o extract_v our_o common_a niter_n whereas_o the_o particle_n of_o water_n be_v more_o flexile_a and_o not_o so_o close_o combine_v together_o recede_v and_o give_v way_n to_o its_o penetration_n so_o that_o this_o aereal_a salt_n enter_v to_o the_o bottom_n of_o the_o deep_a water_n without_o which_o the_o very_a eel_n though_o bed_v in_o the_o mud_n can_v live_v and_o carp_n have_v be_v know_v to_o live_v by_o air_n only_o two_o or_o three_o day_n out_o of_o water_n both_o which_o experiment_n be_v best_o manifest_v in_o extreme_a cold_a and_o frosty_a time_n when_o the_o ice_n do_v prevent_v the_o ingress_n of_o aereal_a particle_n into_o the_o bottom_n of_o the_o water_n and_o the_o cold_a do_v condense_a they_o for_o the_o other_o preservation_n in_o great_a frost_n i_o have_v know_v in_o pond_n quite_o freeze_v over_o multitude_n of_o fish_n for_o want_v of_o air_n sometime_o as_o it_o be_v smother_v sometime_o sick_a and_o faint_o swim_v towards_o small_a venthole_n where_o air_n be_v let_v in_o to_o they_o by_o break_v the_o ice_n to_o keep_v they_o alive_a but_o to_o this_o i_o have_v hear_v some_o answer_n that_o they_o have_v never_o break_v their_o pool_n at_o all_o add_v yet_o their_o fish_n have_v do_v well_o and_o it_o may_v be_v so_o sometime_o for_o in_o a_o great_a frost_n the_o water_n be_v very_o apt_a to_o sink_v from_o the_o ice_n and_o leave_v a_o hollow_a in_o the_o side_n for_o the_o air_n to_o enter_v and_o i_o have_v be_v certain_o tell_v of_o eel_n that_o have_v creep_v out_o of_o the_o deep_a and_o their_o warm_a mud-bed_n for_o want_v of_o air_n and_o have_v lie_v dead_a at_o the_o side_n in_o the_o extreme_a cold_a winter_n which_o have_v they_o be_v so_o much_o offend_v with_o cold_a as_o some_o have_v think_v they_o be_v they_o may_v easy_o have_v keep_v their_o former_a station_n and_o so_o have_v remain_v ab_fw-la hac_fw-la coeli_fw-la inclementia_fw-la tuti_fw-la or_o else_o perhaps_o such_o pool_n have_v quick-spring_n run_v into_o they_o unto_o the_o head_n of_o which_o spring_v the_o eel_n will_v common_o swim_v up_o for_o air_n when_o the_o body_n of_o the_o pool_n be_v quite_o freeze_v over_o where_o by_o the_o bye_n let_v i_o also_o make_v this_o further_a observation_n that_o the_o great_a and_o more_o subtle_a fish_n though_o they_o swim_v near_o the_o bottom_n yet_o they_o choose_v to_o be_v direct_o under_o those_o hole_n by_o which_o it_o be_v apparent_a that_o these_o aereal_a particle_n be_v neither_o reflect_v nor_o refract_v but_o by_o the_o interposition_n of_o another_o body_n which_o they_o can_v enter_v be_v otherwise_o press_v direct_o downward_o but_o to_o return_v chap._n iii_o the_o air_n have_v this_o penetrate_a force_n upon_o earth_n and_o water_n