of_o the_o muscle_n of_o the_o gut_n stomach_n tendon_n membrane_n and_o the_o like_a fibrose_n part_n natural_o resist_v distraction_n and_o have_v a_o power_n of_o contract_v themselves_o after_o extension_n yea_o more_o we_o see_v that_o all_o fibres_fw-fr even_o in_o their_o natural_a posture_n be_v somewhat_o upon_o the_o stretch_n for_o when_o they_o be_v cut_v they_o instant_o shorten_v themselves_o towards_o both_o end_n which_o will_v not_o happen_v if_o they_o have_v be_v constitute_v in_o a_o middle_a state_n betwixt_o laxity_n and_o extension_n as_o a_o bow_n unbend_v be_v quiet_a suffer_v neither_o contraction_n nor_o distraction_n of_o its_o part_n now_o if_o all_o fibre_n even_o in_o their_o natural_a state_n suffer_v some_o degree_n of_o stretch_v certain_o when_o the_o artery_n be_v replenish_v with_o blood_n their_o cavity_n must_v be_v dilate_v and_o in_o the_o dilatation_n of_o their_o cavity_n their_o transverse_n or_o circular_a fibre_n must_v suffer_v much_o more_o stretch_v than_o they_o do_v before_o and_o because_o to_o this_o dilatation_n of_o the_o artery_n a_o constriction_n immediate_o succeed_v which_o be_v not_o possible_a to_o be_v effect_v without_o a_o abbreviation_n of_o the_o circular_a fibres_fw-fr of_o the_o artery_n and_o because_o that_o abbreviation_n or_o contraction_n be_v connatural_a to_o the_o fibre_n themselves_o therefore_o it_o be_v impossible_a that_o the_o artery_n after_o that_o violent_a stretch_v cause_v by_o their_o repletion_n and_o turgency_n shall_v not_o exercise_v by_o natural_a necessity_n that_o mechanic_a power_n they_o have_v of_o contract_v themselves_o by_o virtue_n of_o their_o circular_a fibre_n gird_v they_o inward_a and_o equal_o impossible_a that_o the_o artery_n shall_v so_o contract_v themselves_o without_o expel_v at_o the_o same_o time_n out_o of_o their_o orifice_n the_o blood_n that_o dilate_a they_o whence_o it_o appear_v beyond_o dispute_n that_o the_o spontaneous_a constriction_n of_o the_o distend_v artery_n be_v the_o cause_n of_o the_o expulsion_n of_o the_o blood_n out_o of_o they_o into_o the_o substance_n of_o the_o part_n contrary_a to_o their_o opinion_n who_o ascribe_v this_o expulsion_n only_o to_o the_o systole_n of_o the_o heart_n ¶_o ⸪_o the_o natural_a method_n of_o acquire_a science_n you_o know_v be_v to_o begin_v from_o thing_n more_o know_v and_o then_o to_o advance_v to_o thing_n less_o know_v to_o proceed_v from_o effect_n to_o their_o cause_n see_v therefore_o that_o we_o be_v now_o certain_a that_o the_o blood_n in_o animal_n be_v carry_v by_o a_o perpetual_a circular_a motion_n through_o all_o part_n of_o the_o body_n our_o next_o business_n be_v to_o inquire_v what_o be_v the_o cause_n of_o this_o admirable_a motion_n as_o well_o the_o final_a as_o the_o efficient_a i_o begin_v from_o the_o final_a it_o be_v a_o question_n worthy_a our_o consideration_n why_o or_o to_o what_o end_n nature_n all_o who_o counsel_n and_o action_n be_v ordain_v by_o a_o infinite_a wisdom_n have_v institute_v this_o rapid_a circulation_n of_o the_o blood_n constant_a it_o be_v even_o from_o common_a experience_n that_o whenever_o the_o blood_n be_v quiet_a or_o cease_v from_o motion_n whether_o within_o or_o without_o the_o body_n of_o a_o animal_n the_o red_a and_o grumose_n part_v of_o it_o soon_o curdle_n and_o be_v separate_v from_o the_o serose_n or_o albumen_n and_o so_o the_o constitution_n or_o contexture_n of_o it_o be_v dissolve_v and_o corrupt_v whereas_o on_o the_o contrary_a while_o the_o blood_n continue_v in_o perpetual_a motion_n within_o its_o vessel_n in_o the_o body_n of_o a_o live_a animal_n so_o long_o the_o ordinate_a mixture_n of_o its_o element_n due_a temper_n and_o vital_a constitution_n of_o it_o be_v conserve_v for_o mechanical_a reason_n in_o our_o ensue_a discourse_n to_o be_v explain_v it_o seem_v then_o that_o such_o a_o mixture_n of_o the_o constituent_a part_n of_o the_o blood_n upon_o which_o the_o vitality_n of_o it_o do_v necessary_o depend_v can_v be_v otherwise_o conserve_v than_o by_o a_o continual_a agitation_n and_o concussion_n make_v in_o the_o vessel_n first_o by_o the_o heart_n with_o strong_a force_n impel_v the_o blood_n through_o the_o artery_n then_o that_o impulsive_a force_n languish_v by_o filtration_n in_o the_o space_n intermediate_v betwixt_o the_o artery_n and_o vein_n next_o in_o the_o vein_n by_o the_o constriction_n of_o their_o circular_a fibre_n by_o the_o compression_n of_o the_o muscle_n and_o the_o viscera_n and_o the_o inspire_a air_n all_o which_o compression_n will_v not_o suffice_v be_v not_o valve_n place_v commodious_o within_o the_o vein_n by_o which_o the_o motion_n of_o the_o blood_n be_v accelerate_a and_o a_o far_a conquassation_n of_o it_o make_v and_o here_o we_o meet_v with_o a_o fair_a occasion_n to_o reflect_v upon_o the_o mutual_a anastomôse_n of_o the_o capillary_a vein_n and_o the_o infrequent_a distribution_n of_o valve_n in_o one_o and_o the_o same_o vein_n for_o both_o these_o contribute_v also_o their_o proportion_n towards_o the_o end_n now_o under_o our_o disquisition_n for_o the_o texture_n of_o the_o vein_n be_v indeed_o lax_n and_o soft_a yet_o such_o as_o may_v by_o virtue_n of_o their_o circular_a fibre_n be_v constringe_v and_o contract_v hence_o it_o be_v that_o by_o the_o blood_n regurgitate_v in_o those_o tract_n of_o the_o vein_n that_o have_v no_o valve_n by_o the_o great_a quantity_n and_o force_n of_o its_o regurgitation_n or_o recoil_n the_o low_a part_n of_o the_o vein_n be_v much_o dilate_v and_o on_o the_o contrary_a the_o high_a part_n be_v contract_v so_o that_o the_o blood_n be_v by_o this_o reflux_n though_o inobservable_a agitate_a and_o conquassated_a may_v revive_v its_o due_a commistion_n and_o conserve_v its_o vital_a constitution_n it_o appear_v then_o the_o defect_n of_o valve_n also_o have_v its_o use_n within_o the_o cavity_n of_o the_o artery_n as_o i_o say_v before_o no_o valve_n be_v place_v because_o the_o grand_a force_n by_o which_o the_o blood_n be_v impel_v through_o they_o be_v more_o than_o sufficient_a to_o conquassate_fw-it and_o commix_v it_o by_o wedge_v in_o as_o it_o be_v the_o more_o fluid_a albugineous_a particle_n among_o the_o red_a grumose_n particle_n that_o from_o both_o sort_n commix_v per_fw-la minimas_fw-la moleculas_fw-la as_o they_o say_v and_o yet_o mutual_o reluctant_a the_o vital_a mication_n or_o oscillatory_n intestine_a motion_n of_o the_o blood_n may_v be_v continue_v so_o then_o here_o be_v neither_o need_n of_o nor_o place_n for_o a_o fermentation_n now_o from_o the_o consideration_n of_o these_o thing_n premise_v i_o conclude_v that_o the_o circulation_n of_o the_o blood_n be_v institute_v for_o the_o conservation_n of_o its_o requisite_a temper_n and_o vital_a constitution_n which_o be_v to_o be_v inquire_v and_o which_o lead_v we_o to_o the_o admirable_a effect_n and_o benefit_n arise_v to_o the_o animal_n oeconomy_n from_o the_o same_o velocity_n of_o the_o circulation_n of_o the_o blood_n which_o be_v certain_o so_o great_a that_o the_o whole_a mass_n of_o blood_n run_v its_o circular_a race_n in_o the_o twenty_o part_n of_o a_o hour_n or_o thereabouts_o even_o in_o a_o sedentary_a and_o sedate_v man_n as_o have_v by_o many_o be_v demonstrate_v from_o the_o quantity_n of_o blood_n common_o contain_v in_o the_o body_n from_o the_o number_n of_o pulse_n make_v in_o a_o hour_n and_o from_o the_o quantity_n of_o blood_n express_v by_o every_o pulse_n of_o the_o heart_n and_o we_o have_v already_o see_v what_o advantage_n redound_v to_o the_o blood_n itself_o from_o this_o velocity_n our_o curiosity_n spur_v we_o on_o to_o inquire_v also_o what_o other_o scope_n or_o end_n nature_n may_v probable_o be_v conceive_v to_o have_v propose_v to_o herself_o when_o she_o institute_v this_o so_o rapid_a motion_n or_o what_o emolument_n and_o benefit_n from_o thence_o redound_v to_o the_o oeconomy_n of_o the_o whole_a body_n of_o these_o the_o first_o seem_v to_o be_v this_o that_o in_o every_o pulsation_n of_o the_o heart_n a_o great_a quantity_n of_o blood_n be_v effuse_v and_o protrude_v out_o of_o the_o capillary_a artery_n into_o the_o habit_n of_o the_o part_n for_o their_o refocillation_n by_o influent_a life_n of_o which_o i_o have_v former_o discourse_v copiose_o in_o this_o place_n for_o by_o how_o much_o swift_a the_o motion_n of_o any_o liquor_n or_o other_o fluid_a through_o a_o pipe_n or_o canal_n be_v so_o much_o a_o great_a quantity_n of_o it_o be_v in_o equal_a time_n effuse_v at_o the_o orifice_n thereof_o as_o have_v be_v ingenious_o demonstrate_v by_o b._n castellus_n fluxu_fw-la and_o therefore_o the_o blood_n be_v like_o a_o full_a and_o rapid_a torrent_n impel_v into_o the_o pore_n of_o the_o flesh_n and_o viscera_n the_o second_o be_v the_o energy_n of_o the_o stroke_n with_o which_o the_o blood_n project_v by_o the_o heart_n dash_v against_o the_o same_o extreme_a part_n which_o energy_n be_v
carry_v on_o the_o resemblance_n a_o little_a far_o i_o soon_o discover_v the_o disparity_n to_o be_v so_o many_o and_o so_o great_a that_o it_o be_v impossible_a to_o reconcile_v they_o into_o a_o just_a analogy_n whereupon_o condemn_v the_o extravagance_n of_o my_o fancy_n i_o sober_o conclude_v that_o the_o heart_n of_o a_o animal_n be_v a_o engine_n never_o to_o be_v imitate_v by_o human_a art_n and_o i_o find_v myself_o more_o incline_v to_o applaud_v the_o judgement_n of_o that_o prodigy_n of_o mathematical_a knowledge_n archimedes_n of_o syracuse_n for_o never_o attempt_v to_o counterfeit_v the_o motion_n of_o the_o heart_n than_o to_o admire_v his_o wit_n show_v in_o make_v a_o sphere_n of_o glass_n athan._n 1._o kircher_n deny_v that_o any_o part_n of_o it_o be_v glass_n but_o only_o the_o outside_n that_o man_n may_v discern_v the_o wheel_n and_o motion_n within_o which_o represent_v the_o perfect_a order_n and_o motion_n of_o the_o celestial_a body_n and_o which_o claudian_n describe_v in_o one_o of_o his_o epigram_n now_o if_o we_o desire_v clear_o to_o understand_v this_o inimitable_a excellency_n of_o the_o machine_n of_o the_o heart_n and_o in_o what_o propriety_n of_o it_o the_o same_o do_v chief_o consist_v we_o shall_v be_v oblige_v well_o to_o consider_v two_o thing_n neither_o of_o which_o have_v yet_o be_v explicate_v by_o we_o and_o without_o a_o due_a explication_n of_o both_o which_o all_o that_o we_o have_v hitherto_o say_v concern_v the_o motion_n of_o the_o heart_n will_v be_v maim_v and_o unsatisfactory_a these_o be_v the_o mighty_a and_o incredible_a motive_n force_v of_o the_o heart_n by_o which_o it_o express_v the_o blood_n out_o of_o the_o ventricles_n and_o the_o efficient_a cause_n of_o its_o motion_n thing_n so_o worthy_a to_o be_v know_v that_o i_o need_v not_o deprecate_v your_o impatience_n most_o candid_a and_o accomplish_a auditor_n if_o i_o detain_v you_o a_o few_o minute_n long_o while_o i_o inquire_v into_o they_o as_o to_o the_o first_o therefore_o viz._n the_o admirable_a motive_n force_v of_o the_o heart_n since_o the_o round_a and_o conical_a figure_n of_o the_o heart_n do_v not_o permit_v we_o to_o attempt_v the_o measure_n of_o its_o motive_n power_n by_o the_o same_o way_n by_o which_o the_o most_o learned_a alphonsus_n borellus_n have_v with_o singular_a sagacity_n measure_v the_o force_n of_o very_a many_o other_o muscle_n of_o man_n body_n namely_o by_o weight_n suspend_v by_o they_o and_o since_o therefore_o in_o this_o disquisition_n we_o can_v from_o the_o effect_n proceed_v to_o the_o knowledge_n of_o the_o cause_n we_o be_v compel_v from_o some_o other_o sign_n to_o raise_v a_o probable_a conjecture_n whence_o we_o may_v investigate_v the_o greatness_n of_o the_o effect_n and_o this_o sign_n shall_v be_v the_o similitude_n and_o analogy_n which_o the_o muscule_n of_o the_o heart_n seem_v to_o hold_v to_o other_o muscle_n of_o the_o same_o animal_n let_v we_o then_o with_o the_o same_o excellent_a mathematician_n borellus_n in_o who_o footstep_n i_o now_o again_o tread_v suppose_v that_o all_o even_o the_o least_o fibres_fw-fr or_o little_a machine_n of_o the_o same_o or_o divers_a muscules_n in_o the_o same_o animal_n be_v equal_o strong_a and_o exercise_v a_o equal_a motive_n force_n in_o the_o same_o time_n in_o the_o state_n of_o health_n and_o because_o equal_a bulk_n of_o two_o muscle_n contain_v equal_a multitude_n of_o the_o least_o fibres_fw-fr it_o follow_v that_o if_o we_o have_v foreknow_v the_o total_a motive_n power_n of_o one_o of_o the_o two_o equal_a muscle_n we_o shall_v be_v able_a thence_o to_o conjecture_v what_o be_v the_o total_a power_n motive_n also_o of_o the_o other_o therefore_o the_o fleshy_a bulk_n of_o the_o heart_n be_v of_o almost_o equal_a magnitude_n to_o the_o bulk_n of_o one_o of_o the_o temporal_a muscle_n and_o of_o one_o of_o the_o masseter_n and_o borellus_n have_v demonstrate_v to_o we_o the_o total_a motive_n force_v of_o those_o two_o muscle_n we_o may_v probable_o infer_v that_o the_o motive_n force_n of_o the_o heart_n be_v equal_a to_o that_o which_o those_o two_o muscle_n shut_v the_o mandible_a exercise_n now_o because_o no_o entire_a fiber_n of_o these_o two_o muscle_n be_v less_o than_o two_o inch_n long_a take_v all_o the_o fibres_fw-fr one_o with_o another_o that_o the_o excess_n of_o the_o long_a may_v compensate_a the_o defect_n of_o the_o short_a and_o because_o in_o a_o inch_n space_n of_o every_o single_a fiber_n we_o may_v imagine_v more_o than_o twenty_o little_a machine_n or_o rhomboid_a pore_n contain_v like_o the_o link_n of_o a_o chain_n in_o a_o watch_n or_o the_o mesh_n of_o a_o net_n in_o a_o row_n one_o above_o another_o let_v we_o notwithstanding_o suppose_v no_o more_o than_o ten_o small_a fibre_n to_o be_v contain_v in_o that_o space_n therefore_o in_o the_o length_n of_o every_o one_o of_o the_o fibre_n that_o compose_v the_o say_v two_o muscle_n there_o will_v be_v contain_v more_o than_o twenty_o of_o those_o most_o minute_n machine_n and_o since_o the_o weight_n of_o 150_o pound_n may_v be_v suspend_v by_o one_o single_a stratum_n or_o layer_n of_o these_o small_a machine_n of_o the_o same_o muscle_n therefore_o that_o we_o may_v have_v the_o whole_a force_n that_o nature_n exercise_v in_o those_o muscle_n the_o force_n of_o that_o one_o layer_n viz._n that_o which_o be_v able_a to_o sustain_v 150_o pound_n aught_o to_o be_v twenty_o time_n multiply_v wherefore_o the_o whole_a force_n that_o nature_n exercise_n to_o dilate_v all_o the_o rhomboid_a mesh_n or_o pore_n of_o the_o say_v two_o muscle_n when_o they_o act_v be_v great_a than_o the_o force_n of_o 3000_o pound_n weight_n and_o will_v if_o apply_v to_o the_o opposite_a end_n of_o the_o beam_n of_o a_o balance_n preponderate_a if_o then_o every_o most_o minute_n fiber_n of_o the_o heart_n exercise_v in_o the_o systole_n of_o it_o a_o force_n equal_a to_o that_o which_o every_o rhomboidal_a machine_n of_o the_o temporal_a or_o masseter_n muscle_n make_v when_o they_o act_v as_o most_o certain_o it_o do_v the_o motive_n power_n of_o all_o fibre_n of_o the_o muscle_n in_o the_o same_o animal_n in_o the_o state_n of_o health_n be_v equal_a and_o if_o the_o multitude_n of_o least_o fibre_n contain_v in_o those_o two_o muscle_n be_v equal_a to_o the_o multitude_n of_o most_o minute_n fibres_n contain_v in_o the_o muscle_n of_o the_o heart_n as_o the_o visible_a equality_n of_o their_o magnitude_n warrant_v we_o to_o suppose_v it_o to_o be_v we_o may_v thence_o deduce_v this_o conclusion_n that_o the_o force_n which_o all_o the_o most_o minute_n fibres_n of_o the_o heart_n when_o they_o be_v swell_v exercise_v to_o constringe_v the_o ventricles_n i._n e._n when_o they_o act_v all_o together_o exceed_v the_o force_n of_o 3000_o pound_n weight_n and_o will_v preponderate_v if_o it_o be_v apply_v to_o the_o contrary_a end_n of_o the_o beam_n of_o a_o just_a balance_n quod_fw-la erat_fw-la demonstrandum_fw-la and_o thus_o have_v i_o give_v you_o a_o summary_n of_o what_o borellus_n have_v from_o a_o long_a chain_n of_o most_o ingeniose_fw-la proposition_n and_o theorem_n in_o fine_a infer_v i_o come_v therefore_o to_o the._n second_o and_o last_o considerable_a propose_v to_o be_v inquire_v viz._n the_o efficient_a cause_n of_o this_o so_o wonderful_a motive_n force_v of_o the_o heart_n these_o seem_v to_o be_v no_o more_o than_o two_o of_o which_o one_o be_v immediate_a the_o other_o mediate_v as_o to_o the_o the_o former_a viz._n the_o immediate_a cause_n of_o the_o heart_n motive_n power_n we_o be_v not_o to_o expect_v to_o learn_v either_o what_o it_o be_v or_o whence_o it_o proceed_v from_o the_o doctrine_n of_o the_o ancient_n for_o they_o have_v observe_v that_o the_o heart_n be_v not_o as_o all_o the_o other_o muscle_n of_o the_o body_n be_v move_v ad_fw-la arbitrium_fw-la voluntatis_fw-la at_o the_o command_n of_o the_o will_n not_o only_o name_v the_o motion_n of_o those_o voluntary_a and_o the_o motion_n of_o this_o natural_a as_o they_o have_v good_a reason_n to_o do_v but_o also_o conceive_v and_o teach_v the_o cause_n of_o the_o motion_n of_o the_o heart_n to_o be_v divers_a from_o the_o cause_n of_o the_o motion_n of_o the_o rest_n of_o the_o muscle_n and_o according_o constitute_v and_o assign_v to_o the_o heart_n a_o certain_a blind_a and_o unintelligible_a pulsifick_a faculty_n whereto_o alone_o they_o ascribe_v as_o well_o the_o diastole_n as_o the_o systole_n thereof_o which_o they_o have_v no_o just_a reason_n to_o do_v to_o evince_v this_o their_o palpable_a error_n i_o will_v assert_v this_o proposition_n that_o the_o immediate_a motive_n cause_n of_o the_o heart_n be_v the_o very_a same_o with_o that_o by_o which_o the_o muscle_n of_o the_o limb_n be_v move_v voluntary_o first_o it_o be_v most_o evident_a to_o sense_n that_o
the_o muscle_n of_o the_o heart_n be_v compose_v of_o the_o same_o constituent_a part_n with_o all_o other_o muscle_n viz._n of_o bundle_n of_o carnose_n fibres_n of_o the_o same_o tendinose_n and_o contrahible_a substance_n of_o the_o same_o prismatic_a figure_n in_o the_o same_o manner_n dispose_v layer_n upon_o layer_n bind_v down_o by_o mutual_a contexture_n in_o the_o same_o manner_n intersperse_v with_o branch_n of_o nerve_n fasten_v to_o tendon_n and_o enliven_v by_o blood_n irrigate_a they_o out_o of_o the_o artery_n in_o a_o word_n there_o be_v no_o sensible_a difference_n or_o disparity_n the_o figure_n of_o the_o whole_a heart_n except_v which_o yet_o do_v not_o diversify_v the_o organic_n nature_n of_o it_o no_o more_o than_o the_o diversity_n of_o figure_n among_o other_o muscle_n do_v make_v they_o of_o a_o different_a nature_n then_o if_o we_o consider_v the_o action_n of_o both_o the_o heart_n and_o all_o other_o muscle_n we_o shall_v find_v that_o as_o well_o the_o fibre_n of_o the_o heart_n as_o those_o of_o all_o other_o muscle_n act_v by_o contraction_n of_o themselves_o if_o we_o descend_v to_o the_o immediate_a motive_n cause_n and_o the_o mechanic_n mode_n of_o their_o operate_n from_o what_o we_o have_v already_o say_v it_o be_v manifest_a that_o it_o be_v as_o impossible_a for_o the_o heart_n to_o be_v inflate_v and_o move_v by_o a_o incorporeal_a faculty_n or_o by_o spirit_n or_o by_o the_o blood_n alone_o however_o violent_o rush_v into_o it_o or_o by_o the_o same_o blood_n to_o what_o degree_n soever_o rarify_v in_o its_o ventricles_n or_o by_o a_o fermentation_n conflict_n and_o displosion_n of_o acid_n and_o saline_n juice_n meet_v together_o in_o the_o heart_n as_o it_o be_v for_o the_o muscle_n of_o the_o limb_n to_o be_v regular_o move_v by_o the_o same_o cause_n it_o remain_v therefore_o that_o as_o all_o other_o muscle_n be_v move_v by_o contraction_n of_o their_o fibre_n the_o pore_n of_o they_o be_v fill_v and_o distend_v so_o also_o it_o be_v most_o probable_a that_o the_o proxime_fw-la or_o immediate_a cause_n of_o the_o motion_n i_o mean_v only_o the_o constriction_n of_o the_o heart_n be_v the_o dilatation_n or_o distension_n of_o the_o pore_n of_o its_o fibre_n which_o cause_v their_o abbreviation_n or_o contraction_n i._n e._n the_o systole_n of_o the_o heart_n but_o what_o the_o mediate_v cause_o be_v by_o which_o the_o pore_n of_o the_o fibre_n be_v dilate_v to_o the_o abbreviation_n of_o the_o fibre_n themselves_o we_o shall_v after_o a_o few_o minute_n inquire_v in_o the_o mean_a time_n i_o will_v lay_v down_o this_o other_o proposition_n that_o the_o mediate_v cause_n of_o the_o heart_n motion_n seem_v to_o differ_v from_o that_o by_o which_o the_o muscle_n of_o the_o limb_n be_v incite_v to_o voluntary_a motion_n since_o it_o be_v a_o truth_n know_v to_o all_o man_n that_o we_o can_v move_v what_o muscle_n we_o please_v of_o any_o limb_n and_o continue_v their_o motion_n as_o long_o as_o we_o please_v and_o stop_v it_o when_o we_o please_v but_o the_o motion_n of_o the_o heart_n be_v not_o subject_a to_o the_o empire_n of_o our_o will_n but_z like_o that_o of_o a_o mill_n perpetual_a whether_o we_o sleep_v or_o wake_v and_o since_o even_o without_o our_o knowledge_n or_o perception_n the_o heart_n as_o agitate_a by_o a_o certain_a natural_a necessity_n make_v most_o vehement_a and_o almost_o momentany_a stroke_n or_o jerk_n alternate_o short_a and_o isochronical_a or_o equal_o temporaneous_a pause_n interpose_v betwixt_o they_o nor_o ever_o either_o much_o vary_v that_o constant_a rhythm_n of_o its_o pulse_n while_o we_o be_v in_o the_o state_n of_o health_n or_o intermit_v the_o same_o during_o life_n therefore_o certain_o there_o must_v be_v somewhat_o of_o difference_n between_o the_o mediate_a cause_n of_o the_o heart_n natural_a motion_n on_o one_o part_n and_o the_o mediate_a cause_n of_o the_o voluntary_a motion_n of_o all_o other_o muscle_n on_o the_o other_o beside_o in_o a_o egg_n from_o the_o first_o day_n incubation_n of_o the_o hen_n the_o punctum_fw-la saliens_fw-la and_o then_o the_o vesicula_fw-la pulsans_fw-la exhibit_v to_o our_o sight_n this_o dance_n of_o life_n already_o begin_v when_o we_o can_v conceive_v it_o to_o be_v possible_a that_o there_o shall_v be_v in_o that_o first_o rudiment_n of_o the_o foetus_fw-la any_o sensation_n of_o good_a or_o evil_n any_o will_n to_o pursue_v the_o good_a or_o avoid_v the_o evil_a and_o when_o nothing_o of_o the_o brain_n be_v yet_o form_v nay_o more_o in_o the_o heart_n of_o a_o viper_n take_v out_o of_o the_o body_n and_o put_v into_o warm_a water_n the_o pulsation_n be_v observe_v to_o continue_v many_o hour_n when_o by_o reason_n of_o the_o abscission_n of_o the_o nerve_n all_o commerce_n betwixt_o the_o brain_n and_o the_o heart_n be_v extinct_a no_o sensation_n or_o election_n can_v be_v imagine_v to_o ordain_v and_o command_v that_o motion_n wherefore_o we_o be_v oblige_v to_o confess_v that_o the_o first_o and_o mediate_a cause_n of_o the_o heart_n pulsation_n be_v in_o some_o respect_n or_o other_o divers_a from_o that_o whereby_o the_o other_o muscle_n be_v incite_v to_o motion_n at_o the_o command_n of_o the_o will._n but_o to_o explore_v wherein_o this_o nice_a difference_n may_v most_o probable_o consist_v be_v a_o work_n of_o so_o great_a difficulty_n that_o i_o wish_v it_o be_v possible_a for_o i_o to_o revoke_v the_o temerarious_a promise_n i_o make_v to_o attempt_v it_o nor_o shall_v i_o have_v courage_n enough_o to_o carry_v i_o so_o much_o as_o one_o step_n far_o if_o i_o do_v not_o derive_v it_o whole_o from_o the_o well_o know_a candour_n and_o benignity_n of_o my_o most_o learned_a auditor_n for_o the_o remain_a part_n of_o my_o way_n though_o short_a be_v yet_o dark_a and_o rocky_a with_o precipice_n on_o both_o side_n and_o all_o the_o light_n i_o can_v expect_v must_v be_v from_o a_o few_o spark_n strike_v out_o of_o my_o flinty_a subject_n by_o the_o force_n of_o conjecture_n if_o therefore_o i_o chance_v to_o stumble_v or_o err_v humanity_n will_v oblige_v you_o rather_o to_o put_v forth_o your_o hand_n to_o support_v or_o guide_v i_o than_o to_o deride_v my_o blindness_n in_o hope_n of_o this_o favour_n i_o will_v venture_v to_o proceed_v certain_a it_o be_v that_o the_o first_o and_o mediate_a cause_n of_o the_o motion_n of_o the_o heart_n as_o well_o as_o that_o of_o the_o motion_n of_o the_o other_o muscle_n whatsoever_o it_o shall_v at_o length_n be_v find_v to_o be_v be_v derive_v to_o it_o by_o the_o nerve_n from_o the_o brain_n for_o as_o if_o the_o nerve_n insert_v into_o any_o muscle_n be_v strict_o compress_v by_o a_o ligature_n or_o cut_v off_o the_o power_n of_o motion_n in_o that_o muscle_n be_v present_o intercept_v or_o total_o destroy_v as_o common_a experience_n witness_v so_o if_o the_o nerve_n of_o the_o eight_o conjugation_n be_v either_o strict_o compress_v by_o a_o ligature_n round_o about_o or_o cut_v off_o in_o the_o neck_n of_o any_o animal_n there_o sudden_o will_v ensue_v a_o visible_a change_n in_o the_o motion_n of_o his_o heart_n witness_v the_o memorable_a experiment_n make_v by_o dr._n lower_n and_o record_v in_o his_o excellent_a book_n the_o cord_n 2._o where_o he_o affirm_v that_o the_o heart_n which_o before_o reciprocate_v its_o motion_n moderate_o and_o rhythmical_o present_o after_o the_o ligature_n have_v be_v make_v upon_o the_o say_a nerve_n begin_v to_o palpitate_v and_o tremble_v and_o by_o degree_n grow_v more_o and_o more_o languid_a till_o the_o poor_a creature_n die_v which_o be_v within_o two_o day_n other_o experiment_n confirm_v the_o same_o thing_n i_o may_v allege_v if_o it_o be_v not_o universal_o acknowledge_v by_o anatomist_n that_o the_o motive_n force_n of_o the_o heart_n depend_v upon_o some_o influence_n from_o the_o brain_n and_o among_o these_o one_o of_o the_o most_o accurate_a affirm_v that_o nature_n make_v the_o cerebellum_fw-la as_o a_o storehouse_n of_o animal_n spirit_n chief_o for_o the_o use_n of_o the_o heart_n that_o the_o motion_n of_o it_o may_v be_v perpetual_o maintain_v say_v pro_fw-la motu_fw-la cordis_n praestando_fw-la tam_fw-la sedula_fw-la &_o sollicita_fw-la fuit_fw-la naetura_fw-la ut_fw-la 2._o praeter_fw-la nervorum_fw-la propagines_fw-la ubique_fw-la in_o illud_fw-la densè_fw-la distributas_fw-la pro_fw-la continuo_fw-la spirituum_fw-la animalium_fw-la influxu_fw-la cerebellum_fw-la insuper_fw-la quasi_fw-la perenne_fw-fr corum_fw-la promptuarium_fw-la ei_fw-la accommodaverit_fw-la a_o cujus_fw-la benigna_fw-la &_o constante_n influentia_fw-la adeò_fw-la dependet_fw-la ut_fw-la fi_fw-la spirituum_fw-la influxus_fw-la vel_fw-la minimus_fw-la temporis_fw-la momento_n impediatur_fw-la motus_fw-la ejus_fw-la illicò_fw-la deficiat_fw-la but_o why_o have_v i_o recourse_n to_o the_o authority_n of_o man_n when_o nature_n herself_o in_o her_o constant_a process_n of_o form_v the_o part_n of_o a_o embryon_n seem_v to_o
other_o nerve_n especial_o when_o their_o function_n and_o office_n be_v different_a from_o that_o of_o all_o other_o nerve_n and_o no_o less_o than_o the_o pulsation_n of_o the_o heart_n i._n e._n the_o conservation_n of_o life_n itself_o depend_v upon_o that_o difference_n i_o be_o not_o i_o confess_v so_o happy_a as_o certain_o to_o know_v in_o what_o singular_a artifice_n the_o difference_n do_v consist_v but_o be_o notwithstanding_o full_o convince_v there_o be_v some_o difference_n and_o if_o so_o why_o may_v not_o the_o difference_n consist_v in_o such_o a_o artifice_n as_o that_o which_o i_o have_v here_o suppose_v and_o describe_v since_o the_o same_o be_v not_o only_o possible_a but_o facile_a also_o and_o sufficient_a to_o produce_v the_o effect_n require_v viz._n the_o perpetual_a instillation_n of_o the_o roscid_a liquor_n drop_n after_o drop_n into_o the_o fibre_n of_o the_o heart_n if_o this_o be_v grant_v the_o mighty_a difficulty_n be_v solve_v if_o not_o i_o say_v second_o that_o the_o multitude_n of_o nerve_n elonge_v from_o the_o brain_n to_o the_o heart_n ought_v to_o be_v consider_v what_o reason_n can_v we_o imagine_v nature_n to_o have_v have_v when_o she_o furnish_v the_o heart_n with_o so_o many_o nerve_n more_o than_o be_v insert_v into_o any_o two_o nay_o three_o muscle_n even_o of_o the_o first_o rate_n certain_o she_o do_v it_o either_o for_o the_o more_o exquisite_a sense_n or_o for_o the_o more_o copious_a nourishment_n or_o for_o the_o strong_a motion_n of_o the_o heart_n for_o no_o four_o cause_n can_v be_v find_v the_o first_o be_v improbable_a because_o it_o do_v not_o appear_v that_o the_o heart_n excel_v any_o other_o muscle_n in_o the_o sense_n of_o touch_v or_o feel_n and_o because_o there_o seem_v to_o be_v no_o necessity_n of_o its_o be_v endow_v with_o much_o of_o sense_n whether_o we_o respect_v the_o action_n of_o it_o which_o be_v not_o perception_n but_o pulsation_n and_o that_o too_o with_o incredible_a violence_n such_o as_o be_v inconsistent_a with_o delicate_a and_o exquisite_a sense_n or_o whether_o we_o reflect_v upon_o the_o secure_a situation_n of_o it_o which_o be_v in_o the_o centre_n of_o the_o cavity_n of_o the_o thorax_n where_o it_o hang_v free_a and_o defend_v on_o all_o side_n from_o harm_n and_o offence_n either_o from_o within_o or_o from_o without_o the_o second_o also_o be_v improbable_a because_o the_o bulk_n of_o the_o heart_n hold_v no_o just_a proportion_n to_o the_o multitude_n of_o nerve_n insert_v into_o it_o and_o there_o be_v many_o muscle_n of_o far_o great_a magnitude_n which_o yet_o be_v plentiful_o supply_v with_o nourishment_n by_o much_o few_o nerve_n the_o three_o therefore_o be_v true_a and_o by_o consequence_n serve_v to_o disentangle_v our_o hypothesis_n from_o the_o chord_n of_o the_o difficulty_n propose_v for_o so_o great_a a_o number_n of_o nerve_n import_v into_o the_o heart_n much_o more_o of_o the_o nutritive_a liquor_n than_o can_v be_v think_v necessary_a for_o its_o nourishment_n of_o what_o use_n can_v the_o overplus_n be_v unless_o to_o maintain_v the_o perpetual_a motion_n of_o it_o and_o in_o this_o also_o there_o be_v a_o manifest_a difference_n betwixt_o the_o heart_n and_o all_o other_o muscle_n and_o such_o a_o difference_n as_o may_v be_v bring_v for_o one_o reason_n why_o no_o other_o muscle_n but_o the_o heart_n have_v a_o pulsation_n three_o i_o say_v that_o the_o aptitude_n of_o the_o heart_n to_o pulsation_n do_v consist_v in_o its_o proper_a fabric_n and_o conformation_n in_o its_o conical_a figure_n in_o its_o cavity_n within_o in_o the_o disposition_n and_o configuration_n of_o its_o fibre_n in_o a_o word_n in_o its_o whole_a mechanism_n which_o i_o have_v former_o describe_v and_o which_o be_v far_o different_a from_o the_o mechanism_n of_o any_o other_o muscle_n whatsoever_o so_o that_o if_o there_o be_v no_o singular_a artifice_n or_o knack_n in_o the_o structure_n of_o the_o cardiac_n nerve_n or_o if_o these_o nerve_n be_v few_o in_o number_n yet_o may_v the_o heart_n be_v apt_a for_o pulsation_n of_o which_o all_o other_o muscle_n be_v incapable_a as_o want_v the_o like_a mechanic_n conformation_n no_o wonder_n then_o if_o pulsation_n be_v proper_a to_o the_o heart_n only_o though_o the_o fibre_n of_o all_o other_o muscle_n be_v of_o the_o same_o nature_n with_o the_o fibre_n of_o the_o heart_n though_o the_o efficient_a cause_n of_o the_o motion_n of_o all_o other_o muscle_n be_v the_o same_o with_o those_o of_o the_o motion_n of_o the_o heart_n and_o though_o they_o as_o well_o as_o the_o heart_n act_n by_o the_o contraction_n of_o their_o fibre_n now_o if_o no_o one_o of_o the_o three_o reason_n here_o by_o i_o allege_v why_o the_o motion_n of_o pulsation_n be_v not_o common_a to_o all_o the_o rest_n of_o the_o muscle_n take_v single_a be_v think_v sufficient_a yet_o if_o you_o please_v to_o conjoin_v and_o twist_v they_o all_o together_o into_o a_o triple_a chord_n you_o may_v then_o perhaps_o find_v they_o strong_a enough_o to_o pluck_v up_o the_o propose_a difficulty_n by_o the_o root_n but_o hold_v a_o minute_n or_o two_o have_v i_o not_o through_o haste_n or_o want_v of_o due_a circumspection_n run_v myself_o into_o the_o brier_n of_o a_o contradiction_n do_v i_o not_o in_o my_o last_o proposition_n affirm_v that_o the_o mediate_v cause_n of_o the_o natural_a motion_n of_o the_o heart_n differ_v in_o some_o respect_n from_o that_o by_o which_o all_o the_o rest_n of_o the_o muscle_n be_v incite_v and_o invigorate_v to_o voluntary_a motion_n and_o have_v i_o not_o in_o the_o paragraph_n immediate_o precede_v this_o say_v that_o the_o mediate_v cause_n both_o of_o the_o motion_n of_o the_o heart_n and_o of_o the_o motion_n of_o all_o other_o muscle_n be_v one_o and_o the_o same_o viz._n the_o succus_fw-la nervosus_fw-la derive_v from_o the_o brain_n where_o then_o be_v the_o difference_n presume_v i_o answer_v therefore_o that_o the_o difference_n lie_v not_o in_o any_o change_n or_o alteration_n of_o the_o nature_n and_o quality_n of_o the_o succus_fw-la nervosus_fw-la itself_o which_o i_o grant_v to_o be_v the_o same_o utrobique_fw-la on_o both_o part_n but_o only_o in_o the_o divers_a modes_n of_o its_o effusion_n from_o the_o brain_n into_o the_o heart_n i_o suppose_v it_o to_o descend_v through_o the_o cardiac_n nerve_n gentle_o slow_o and_o by_o way_n of_o instillation_n drop_v after_o drop_n but_o into_o the_o rest_n of_o the_o muscle_n i_o suppose_v the_o same_o to_o be_v immit_v with_o great_a force_n and_o velocity_n swift_a as_o lightning_n at_o the_o command_n of_o the_o will._n and_o this_o seem_v to_o be_v sufficient_a to_o constitute_v a_o difference_n where_o the_o same_o cause_n use_v by_o nature_n diversimodè_fw-la and_o in_o organ_n of_o different_a conformation_n produce_v so_o different_a effect_n and_o consequent_o to_o extricate_v i_o from_o the_o brier_n ¶_o ⸫_o from_o which_o as_o well_o as_o from_o the_o former_a impediment_n be_v now_o at_o length_n free_a i_o come_v in_o the_o next_o place_n to_o establish_v the_o grand_a pillar_n upon_o which_o the_o whole_a weight_n of_o this_o my_o rude_a structure_n rely_v that_o be_v to_o make_v it_o appear_v to_o be_v not_o only_o possible_a but_o also_o probable_a that_o a_o few_o little_a drop_n of_o liquor_n instill_v into_o the_o fibre_n of_o the_o heart_n shall_v only_o by_o cause_v they_o to_o swell_v or_o by_o dilate_v their_o pore_n abbreviate_v they_o with_o a_o force_n great_a enough_o to_o make_v a_o constriction_n of_o the_o heart_n this_o if_o i_o shall_v be_v able_a to_o do_v i_o shall_v not_o despair_v of_o finish_v my_o building_n as_o i_o at_o first_o design_v for_o the_o remain_a part_n of_o my_o work_n will_v be_v little_a and_o easy_a as_o for_o the_o possibility_n of_o so_o great_a a_o effect_n from_o a_o cause_n that_o seem_v to_o be_v so_o weak_a and_o inconsiderable_a that_o may_v be_v without_o much_o difficulty_n prove_v from_o the_o just_a analogy_n or_o similitude_n of_o this_o effect_n to_o many_o other_o as_o great_a if_o not_o great_a effect_n common_o observe_v to_o arise_v from_o the_o like_a cause_n for_o mechanic_n example_n of_o this_o kind_n be_v every_o where_o so_o obvious_a to_o sense_n and_o so_o numerose_n that_o only_o to_o enumerate_v they_o will_v be_v a_o task_n hard_a and_o tediose_fw-la out_o of_o so_o vast_a a_o multitude_n therefore_o i_o will_v for_o brevitie_n sake_n select_a only_a two_o such_o as_o be_v not_o only_o pertinent_a and_o adequate_a to_o my_o subject_n but_o also_o in_o themselves_o eminent_o remarkable_a the_o first_o be_v of_o a_o new_a cable_n which_o upon_o wet_n will_v very_o much_o swell_v or_o become_v thick_a shrink_v and_o shorten_v itself_o beyond_o the_o belief_n of_o any_o but_o a_o mariner_n and_o galilaeus_fw-la have_v well_o observe_v this_o swell_a and_o
little_a canales_n within_o must_v therefore_o be_v full_a of_o small_a asperity_n it_o be_v necessary_a that_o the_o succus_fw-la nervosus_fw-la who_o consistence_n be_v not_o much_o thin_a than_o the_o white_a of_o a_o egg_n well_o beat_v shall_v pass_v through_o they_o with_o a_o slow_a and_o interrupt_a course_n and_o at_o length_n fall_v out_o of_o their_o low_a end_n in_o drop_n with_o equal_a pause_n between_o the_o drop_n where_o we_o find_v a_o parility_n of_o cause_n we_o may_v right_o expect_v a_o similitude_n of_o effect_n here_o i_o see_v two_o formidable_a difficulty_n stand_v like_o romantic_a giant_n in_o my_o way_n to_o deter_v i_o from_o proceed_v and_o i_o can_v without_o shame_n and_o infamy_n decline_v to_o encounter_v they_o one_o be_v that_o after_o the_o cardiac_n nerve_n be_v cut_v off_o and_o the_o heart_n itself_o take_v out_o of_o the_o body_n the_o pulsation_n of_o it_o continue_v for_o some_o time_n to_o remove_v this_o therefore_o i_o say_v that_o the_o cavity_n of_o the_o nerve_n annex_v to_o the_o heart_n may_v remain_v still_o full_a of_o and_o turgid_a with_o the_o roscid_n succus_fw-la nervosus_fw-la which_o be_v hinder_v from_o regress_n by_o their_o spontaneous_a contraction_n towards_o the_o heart_n and_o keep_v in_o a_o state_n of_o fluxility_n by_o the_o yet_o last_a warmth_n of_o the_o heart_n may_v for_o some_o time_n be_v instill_v into_o the_o fibre_n of_o it_o and_o by_o swell_v of_o they_o cause_n they_o to_o constringe_v the_o ventricles_n as_o before_o then_o the_o heart_n be_v irritate_v by_o the_o prick_n of_o a_o needle_n or_o some_o sharp_a and_o pungent_a liquor_n may_v be_v able_a by_o its_o peristaltic_a constriction_n to_o squeeze_v out_o the_o few_o remain_a drop_n of_o the_o roscid_a liquor_n which_o be_v do_v the_o pulsation_n cease_v for_o ever_o to_o the_o blood_n this_o effect_n ought_v not_o to_o be_v ascribe_v for_o after_o all_o relic_n of_o it_o have_v be_v with_o warm_a water_n and_o a_o syringe_n wash_v out_o of_o the_o ventricles_n and_o squeeze_v out_o of_o the_o vessel_n the_o pulsation_n notwithstanding_o will_v continue_v for_o sometime_o nor_o can_v it_o be_v with_o more_o reason_n ascribe_v to_o convulsion_n of_o the_o heart_n because_o all_o convulsion_n be_v disorderly_a and_o unequal_a both_o in_o the_o time_n of_o their_o gird_n and_o in_o those_o of_o their_o intermission_n whereas_o in_o this_o case_n the_o pulsation_n be_v regular_a and_o isochronical_a with_o equal_a pause_n nor_o to_o the_o heat_v communicate_v by_o the_o blood_n to_o the_o heart_n before_o it_o be_v exsect_v and_o not_o yet_o quite_o extinct_a because_o that_o borrow_a heat_n soon_o vanish_v and_o no_o external_a heat_n will_v revive_v the_o languish_a pulsation_n after_o all_o the_o roscid_a juice_n have_v be_v express_v out_o of_o the_o end_n of_o the_o nerve_n leave_v in_o the_o heart_n nothing_o then_o remain_v to_o solve_v this_o phaenomenon_n but_o the_o instillation_n of_o a_o few_o drop_n of_o our_o roscid_a liquor_n into_o the_o fibre_n of_o the_o heart_n to_o swell_v they_o and_o so_o urge_v they_o to_o constriction_n of_o the_o ventricles_n the_o other_o difficulty_n be_v this_o why_o be_v there_o not_o a_o pulsation_n after_o the_o same_o manner_n also_o in_o all_o the_o muscle_n of_o the_o limb_n since_o their_o fibre_n be_v of_o the_o same_o nature_n in_o all_o thing_n their_o disposition_n and_o direction_n only_o except_v since_o the_o orifice_n of_o the_o nerve_n pertain_v to_o they_o be_v in_o the_o brain_n as_o open_a to_o admit_v and_o imbibe_n the_o succus_fw-la nervosus_fw-la there_o elaborate_a and_o provide_v for_o they_o and_o since_o the_o same_o nerve_n be_v equal_o spungy_a and_o permeable_a in_o their_o constitution_n and_o so_o apt_a to_o transfer_v that_o liquor_n as_o the_o orifice_n of_o the_o cardiac_n nerve_n be_v to_o receive_v or_o their_o canales_n to_o transfer_v it_o if_o the_o whole_a apparatus_n be_v the_o same_o on_o both_o part_n whence_o come_v it_o that_o the_o same_o effect_n be_v not_o produce_v in_o both_o at_o this_o goliath_n i_o have_v in_o my_o scrip_n three_o pebble_n to_o throw_v and_o though_o my_o arm_n be_v weak_a i_o will_v not_o despair_v of_o hit_v he_o in_o the_o forehead_n first_o therefore_o i_o say_v that_o it_o be_v not_o yet_o certain_o know_v to_o any_o mortal_a man_n by_o what_o mediate_a cause_n the_o muscle_n of_o the_o limb_n be_v move_v at_o the_o command_n of_o the_o will_n whether_o by_o simple_a contraction_n of_o the_o original_n of_o the_o nerve_n insert_v into_o they_o or_o by_o the_o immission_n of_o the_o succus_fw-la nervosus_fw-la more_o copiose_o and_o swift_o at_o the_o time_n of_o their_o be_v put_v into_o action_n though_o the_o mechanism_n of_o their_o fibre_n make_v it_o more_o probable_a that_o they_o be_v move_v by_o immission_n of_o some_o liquor_n from_o the_o brain_n by_o which_o the_o rhomboid_a mesh_n or_o pore_n of_o their_o fibre_n be_v all_o at_o the_o same_o time_n swell_v and_o dilate_v a_o contraction_n of_o the_o whole_a muscle_n must_v in_o the_o same_o moment_n be_v effect_v and_o therefore_o i_o prefer_v this_o opinion_n to_o the_o former_a and_o have_v follow_v it_o in_o many_o place_n of_o this_o rude_a discourse_n but_o yet_o this_o opinion_n have_v not_o lead_v i_o to_o a_o discovery_n of_o the_o cause_n of_o the_o difference_n this_o present_a difficulty_n compel_v i_o to_o hunt_v after_o shall_v i_o imagine_v valve_n affix_v by_o nature_n to_o the_o orifice_n of_o the_o nerve_n of_o the_o muscle_n as_o mons_fw-la des_n cartes_n do_v in_o the_o body_n of_o they_o though_o such_o a_o artifice_n be_v not_o impossible_a yet_o beside_o that_o no_o such_o valve_n have_v hitherto_o be_v find_v in_o the_o brain_n i_o shall_v still_o be_v to_o seek_v for_o a_o cause_n to_o open_v and_o shut_v they_o ad_fw-la arbitrium_fw-la voluntatis_fw-la and_o so_o shall_v be_v put_v to_o a_o stand_n in_o my_o disquisition_n which_o to_o avoid_v some_o other_o organical_a contrivement_n such_o as_o may_v be_v not_o only_o possible_a but_o probable_a also_o and_o facile_a and_o fit_a to_o untie_v this_o gordian_a knot_n must_v be_v excogitated_a let_v it_o then_o be_v suppose_v that_o in_o the_o brain_n the_o orifice_n of_o the_o nerve_n thence_o elonge_v to_o the_o muscle_n of_o the_o limb_n and_o their_o canales_n be_v in_o such_o a_o peculiar_a manner_n form_v as_o at_o no_o time_n to_o take_v in_o and_o convey_v into_o the_o muscle_n more_o of_o the_o roscid_a liquor_n than_o what_o be_v sufficient_a to_o nourish_v they_o and_o recruit_v their_o vigour_n unless_o when_o at_o the_o command_n of_o the_o will_n under_o who_o jurisdiction_n they_o proper_o be_v the_o nerve_n be_v twitch_v up_o or_o convel_v at_o their_o original_n both_o their_o orifice_n be_v dilate_v to_o receive_v and_o their_o canales_n render_v more_o pervious_a to_o transmit_v in_o a_o moment_n into_o the_o fibre_n of_o the_o muscle_n to_o be_v use_v a_o great_a portion_n of_o the_o same_o invigorate_n liquor_n viz._n so_o much_o as_o be_v requisite_a to_o swell_v they_o up_o by_o replenish_n their_o pore_n and_o force_v they_o to_o contraction_n which_o be_v the_o common_a action_n of_o all_o muscle_n on_o the_o other_o part_n let_v it_o be_v suppose_v that_o in_o the_o brain_n nature_n have_v frame_v the_o original_n of_o the_o cardiac_n nerve_n by_o a_o different_a artifice_n namely_o such_o as_o that_o not_o only_o their_o orifice_n may_v always_o be_v open_a to_o imbibe_n but_o also_o their_o canales_n so_o easy_o pervious_a to_o transmit_v the_o roscid_a liquor_n as_o that_o without_o any_o vellication_n without_o any_o convulsive_a motion_n the_o same_o liquor_n may_v mere_o by_o the_o plenitude_n of_o the_o canales_n themselves_o be_v effuse_v guttulatim_fw-la into_o the_o fibre_n of_o the_o heart_n to_o cause_v the_o alternate_a constriction_n or_o pulsation_n of_o it_o and_o it_o be_v the_o more_o lawful_a for_o i_o to_o suppose_v this_o difference_n of_o structure_n in_o nerve_n ordain_v for_o different_a use_n because_o it_o be_v above_o all_o doubt_n that_o the_o optic_a nerve_n have_v a_o peculiar_a fabric_n and_o contexture_n wherein_o they_o differ_v from_o the_o auditory_a and_o all_o other_o nerve_n inservient_fw-la to_o the_o rest_n of_o the_o external_a sense_n and_o that_o the_o organ_n of_o every_o sense_n have_v its_o nerve_n of_o a_o peculiar_a constitution_n accommodate_v to_o the_o nature_n of_o its_o proper_a object_n though_o those_o difference_n consist_v in_o such_o minute_n and_o subtle_a artifices_fw-la as_o have_v hitherto_o elude_v our_o most_o curiose_fw-la research_v though_o assist_v by_o the_o best_a sort_n of_o microscope_n why_o then_o may_v it_o not_o be_v think_v that_o nature_n have_v give_v to_o the_o cardiac_n nerve_n also_o a_o constitution_n divers_a from_o that_o of_o all_o
see_v that_o the_o liquor_n find_v in_o the_o pericardium_n be_v easy_o capable_a of_o coagulation_n either_o by_o heat_n or_o cold_a so_o as_o to_o become_v like_o jelly_n of_o hartshorn_n or_o the_o white_a of_o a_o egg_n harden_v by_o boil_v as_o the_o serum_fw-la of_o the_o blood_n will_v do_v and_o observe_v the_o various_a little_a gland_n seat_v about_o the_o basis_n of_o the_o heart_n for_o which_o i_o can_v find_v no_o other_o equal_o probable_a use_n as_o to_o instil_v the_o serum_fw-la into_o the_o pericardium_n to_o facilitate_v the_o motion_n of_o the_o heart_n which_o most_o certain_o that_o liquor_n do_v as_o the_o humour_n instill_v out_o of_o the_o glandulae_fw-la lacrymale_n upon_o the_o outside_n of_o the_o eye_n serve_v to_o moisten_v and_o make_v they_o more_o easy_o movable_a every_o way_n when_o i_o have_v i_o say_v observe_v and_o consider_v these_o thing_n i_o reject_v that_o thought_n and_o embrace_v this_o of_o the_o absorption_n of_o the_o relic_n of_o the_o succus_fw-la nervosus_fw-la by_o the_o vein_n of_o the_o heart_n the_o second_o be_v that_o the_o diastole_n of_o the_o heart_n be_v cause_v partly_o by_o the_o relaxation_n of_o the_o fibre_n of_o it_o spontaneous_o restore_v themselves_o to_o their_o natural_a posture_n and_o length_n as_o all_o other_o tensile_n body_n be_v wont_a to_o do_v after_o they_o have_v be_v distend_v partly_o by_o the_o force_n of_o the_o blood_n rush_v out_o of_o the_o ear_n into_o the_o ventricles_n of_o the_o heart_n and_o replenish_n they_o wherefore_o the_o wisdom_n of_o nature_n be_v admirable_a also_o in_o this_o that_o she_o ordain_v these_o two_o cause_n of_o the_o diastole_n viz._n the_o relaxation_n of_o the_o fibre_n and_o the_o influx_n of_o the_o blood_n into_o the_o ventricles_n to_o be_v exact_o coincident_a that_o with_o unite_a force_n they_o may_v cooperate_v more_o efficacious_o whence_o it_o appear_v that_o in_o the_o diastole_n the_o heart_n be_v not_o whole_o passive_a as_o all_o anatomist_n hitherto_o have_v believe_v it_o to_o be_v for_o unless_o the_o fibres_n do_v restore_v themselves_o to_o their_o former_a longitude_n which_o be_v a_o natural_a action_n at_o the_o same_o time_n the_o influx_n of_o the_o blood_n happen_v certain_o there_o can_v be_v no_o room_n to_o receive_v the_o blood_n because_o the_o inside_n of_o the_o ventricles_n will_v continue_v to_o touch_v each_o the_o other_o and_o so_o there_o can_v be_v no_o diastole_n the_o three_o and_o last_o be_v that_o it_o appear_v from_o the_o whole_a series_n of_o this_o discourse_n that_o the_o pulsation_n or_o constriction_n of_o the_o heart_n have_v its_o force_n from_o that_o mechanic_n power_n which_o be_v call_v the_o wedge_n and_o that_o the_o blood_n be_v express_v out_o of_o the_o heart_n by_o virtue_n of_o another_o mechanic_n power_n which_o be_v name_v the_o praelum_fw-la or_o press_n and_o consequent_o that_o the_o heart_n itself_o be_v as_o all_o automata_n be_v move_v not_o by_o spirit_n nor_o by_o a_o pulsifick_a faculty_n nor_o by_o rarefaction_n of_o the_o blood_n nor_o ebullition_n or_o fermentation_n of_o the_o blood_n nor_o by_o explosion_n of_o saline_n and_o acid_n spirituose_fw-la liquor_n but_o by_o mechanic_n necessity_n which_o from_o the_o beginning_n i_o hope_v i_o shall_v be_v able_a fair_o to_o prove_v if_o the_o success_n of_o my_o endeavour_n have_v not_o be_v answerable_a to_o that_o hope_n i_o will_v not_o go_v about_o to_o extenuate_v the_o blame_n of_o my_o faileur_n by_o cite_v example_n of_o much_o great_a wit_n which_o have_v before_o i_o in_o vain_a attempt_v to_o reveal_v the_o same_o secret_a of_o nature_n but_o consolate_v myself_o with_o this_o that_o my_o judge_n be_v man_n no_o less_o belove_v for_o their_o exemplary_a candour_n and_o humanity_n than_o honour_v for_o their_o excellency_n in_o all_o kind_n of_o learning_n and_o who_o need_v not_o be_v put_v in_o mind_n that_o truth_n be_v a_o tree_n who_o root_n be_v in_o heaven_n and_o of_o which_o even_o the_o wise_a of_o we_o dim-sighted_a mortal_n here_o upon_o earth_n see_v nothing_o but_o the_o shadow_n of_o its_o branch_n i_o will_v therefore_o conclude_v this_o inelaborate_a disquisition_n with_o that_o memorable_a say_n of_o the_o prince_n of_o roman_a orator_n consolation_n de_n his_o statuat_fw-la unusquisque_fw-la ut_fw-la libet_fw-la quid_fw-la autem_fw-la verius_fw-la sit_fw-la deus_fw-la ipse_fw-la viderit_fw-la hominem_fw-la quidem_fw-la scire_fw-la arbitror_fw-la neminem_fw-la ¶_o ⸫_o my_o lecture_n such_o as_o they_o be_v much_o honour_a auditor_n you_o have_v with_o oblige_a patience_n hear_v be_v please_v i_o beseech_v you_o to_o hear_v also_o before_o you_o rise_v a_o word_n which_o i_o have_v to_o speak_v in_o my_o own_o defence_n be_v it_o not_o indecent_a to_o compare_v small_a thing_n with_o great_a i_o shall_v venture_v perhaps_o to_o advertise_v you_o that_o the_o reason_n which_o induce_v i_o to_o attempt_v a_o reformation_n of_o the_o borellian_a hypothesis_n of_o the_o motion_n of_o the_o heart_n which_o doctor_n harvey_n himself_o call_v the_o sun_n of_o the_o microcosm_n sanguine_a seem_v to_o have_v some_o kind_n of_o analogy_n to_o those_o which_o move_v the_o prince_n of_o astronomer_n tycho_n brahe_n to_o dislike_v the_o ptolemaic_a system_n of_o the_o macrocosm_n or_o great_a world_n and_o to_o excogitate_v a_o new_a one_o of_o more_o probability_n and_o neatness_n for_o as_o tycho_n animadvert_v that_o the_o celestial_a orb_n have_v be_v by_o ptolemy_n distribute_v unhansom_o that_o so_o many_o and_o so_o great_a epicycle_n be_v in_o vain_a imagine_v to_o explicate_v the_o retrogradation_n of_o the_o planet_n and_o their_o various_a respect_n to_o the_o sun_n and_o that_o the_o equality_n of_o the_o circular_a motion_n be_v measure_v not_o from_o the_o centre_n of_o its_o proper_a circle_n as_o it_o ought_v but_o from_o the_o centre_n of_o another_o eccentric_a circle_n against_o the_o first_o principle_n of_o nature_n and_o art_n invent_v a_o new_a system_fw-la exempt_a from_o all_o these_o incommodity_n which_o be_v in_o truth_n the_o copernican_n invert_v so_o i_o conceive_v that_o in_o the_o borellian_a hypothesis_n and_o explosion_n of_o i_o know_v not_o what_o saline_n and_o acid_n material_n in_o the_o heart_n be_v not_o only_o in_o itself_o extreme_o improbable_a and_o incongruous_a to_o the_o wisdom_n of_o nature_n which_o always_o constitute_v certain_a and_o regular_a cause_n to_o produce_v certain_a and_o regular_a effect_n but_o also_o unnecessary_o suppose_v to_o solve_v the_o phaenomenon_n of_o the_o heart_n pulsation_n set_v my_o dull_a brain_n on_o work_n to_o reform_v it_o and_o soon_o invent_v another_o that_o seem_v both_o free_a from_o those_o inconvenience_n and_o more_o agreeable_a to_o the_o organical_a structure_n of_o the_o heart_n to_o which_o above_o all_o thing_n it_o be_v requisite_a i_o shall_v endeavour_v to_o adjust_a it_o this_o i_o think_v myself_o oblige_v to_o signify_v lest_o any_o here_o shall_v believe_v either_o that_o i_o have_v usurp_v to_o myself_o this_o whole_a system_n of_o the_o motion_n of_o the_o heart_n from_o that_o most_o excellent_a mathematician_n alphonsus_n borellus_n who_o memory_n i_o high_o honour_n or_o that_o i_o lay_v claim_n to_o more_o than_o a_o candid_a attempt_n to_o reform_v it_o ¶_o ⸫_o epilogus_fw-la praelectionum_fw-la quidem_fw-la vela_fw-la jam_fw-la tandem_fw-la contraxi_fw-la nondum_fw-la tamen_fw-la dissolutam_fw-la video_fw-la concionem_fw-la resistamus_fw-la igitur_fw-la hîc_fw-la parumper_fw-la auditores_fw-la ornatissimâ—_n si_fw-la vobis_fw-la ita_fw-la videatur_fw-la &_o ad_fw-la stupendam_fw-la illam_fw-la cujus_fw-la rationem_fw-la mechanicam_fw-la hactenus_fw-la tam_fw-la anxiè_fw-la inquisivimus_fw-la cordis_n fabricam_fw-la seriò_fw-la respiciamus_fw-la ind_n enim_fw-la etiamsi_fw-la alia_fw-la omne_fw-la in_o universitate_fw-la rerum_fw-la deessent_fw-la divinae_fw-la architecturae_fw-la documenta_fw-la cuivis_fw-la hominum_fw-la pronum_fw-la est_fw-la infer_v &_o quam_fw-la sit_fw-la immensa_fw-la illius_fw-la caeterorumque_fw-la omnium_fw-la in_o hoc_fw-la mundo_fw-la adspect_n abilium_fw-la conditoris_fw-la solertia_fw-la quámque_fw-la parum_fw-la ab_fw-la immedicabili_fw-la cum_fw-la animi_fw-la tum_fw-la mentis_fw-la stupiditate_fw-la olim_fw-la abfuerit_fw-la epicurus_n qui_fw-la animalia_fw-la casu_fw-la quodam_fw-la in_fw-la prima_fw-la rerum_fw-la procreatione_fw-la genita_fw-la fuisse_fw-la vecorditer_fw-la censuit_fw-la &_o opinatus_fw-la est_fw-la consequenter_fw-la totam_fw-la in_o iis_fw-la membrorum_fw-la varietatem_fw-la dearticulationemque_fw-la non_fw-la aliunde_fw-la quam_fw-la ex_fw-la atomorum_fw-la fortè_fw-la fortuna_fw-la post_fw-la infinitos_fw-la inter_fw-la se_fw-la in_o spatio_fw-la infinito_fw-la vortices_fw-la ita_fw-la concurrentium_fw-la atque_fw-la commistarum_fw-la dispositione_n extitisse_fw-la quamobrem_fw-la neque_fw-la ullam_fw-la fuisse_fw-la intelligentis_fw-la naturae_fw-la prudentiam_fw-la quae_fw-la ossa_fw-la cerebrum_fw-la cor_fw-la nervos_fw-la venas_fw-la quae_fw-la oculos_fw-la manus_fw-la pedes_fw-la viscera_fw-la quae_fw-la cetera_fw-la omne_fw-la conformans_fw-la ad_fw-la fine_n certos_fw-la seu_fw-la functiones_fw-la partibus_fw-la congruas_fw-la respexerit_fw-la sed_fw-la singulas_fw-la part_n ita_fw