guilty_a of_o a_o no_o small_a fault_n in_o force_v if_o i_o may_v say_v so_o his_o patient_n to_o drink_v wine_n and_o to_o eat_v solid_a food_n during_o the_o whole_a time_n of_o continue_a fever_n and_o in_o time_n of_o the_o fit_a in_o ague_n for_o though_o in_o the_o abatement_n of_o the_o one_o and_o the_o intermission_n of_o the_o other_o that_o kind_n of_o nourishment_n may_v back_o and_o fortify_v the_o operation_n of_o the_o remedy_n yet_o they_o considerable_o oppress_v the_o patient_n when_o nature_n be_v take_v up_o in_o defend_v herself_o against_o the_o vigour_n of_o the_o distemper_n that_o attack_n she_o and_o then_o it_o appear_v that_o the_o prudence_n and_o skill_n of_o a_o learned_a and_o experience_a physician_n be_v at_o least_o of_o as_o great_a relief_n on_o such_o occasion_n as_o the_o most_o efficacious_a and_o salutory_a medicine_n i_o have_v no_o more_o to_o say_v to_o show_v how_o little_a confidence_n we_o ought_v to_o have_v in_o such_o kind_n of_o empiric_n but_o that_o it_o be_v strange_a that_o this_o man_n who_o have_v prescribe_v to_o we_o so_o many_o juice_n and_o such_o like_a trifle_n about_o the_o composition_n of_o his_o febrifuge_n whereof_o the_o principle_n effect_n be_v only_o to_o be_v attribute_v to_o the_o jesuit_n powder_n shall_v conceal_v the_o use_n that_o he_o make_v of_o opium_n whereof_o he_o many_o time_n add_v some_o drop_n of_o tincture_n to_o this_o febrifuge_n which_o may_v be_v of_o great_a advantage_n when_o it_o be_v give_v seasonable_o in_o over_o watch_n light_a headedness_n and_o looseness_n which_o be_v frequent_a symptom_n in_o fever_n and_o always_o allay_v by_o the_o virtue_n of_o that_o excellent_a medicine_n i_o hope_v the_o reader_n will_v take_v in_o good_a part_n that_o i_o describe_v in_o this_o place_n a_o febrifuge_n opiate_n prepare_v with_o quinquina_fw-la and_o afterward_o explain_v its_o effect_n with_o relation_n to_o the_o nature_n of_o fever_n and_o ague_n a_o excellent_a febrifuge_n take_v of_o the_o jesuit_n powder_n the_o flower_n or_o leaf_n of_o lesser_a centaury_n subtle_o pulverize_v and_o of_o treacle_n of_o each_o a_o like_a weight_n make_v they_o into_o a_o opiate_n of_o which_o the_o patient_n twice_o a_o day_n shall_v take_v the_o weight_n of_o a_o drachm_n and_o a_o half_a during_o the_o space_n of_o six_o day_n drink_v upon_o it_o a_o glass_n of_o good_a claret_n with_o plantin_n or_o bugloss_n water_n reflection_n upon_o the_o use_n of_o this_o febrifuge_n the_o excellency_n of_o a_o remedy_n be_v very_o often_o the_o cause_n why_o it_o be_v despise_v antimony_n have_v be_v in_o our_o day_n a_o manifest_a instance_n of_o this_o but_o the_o jesuit_n powder_n and_o the_o english_a febrifuge_n continue_v we_o more_o plain_o of_o the_o truth_n of_o it_o so_o soon_o as_o chance_v or_o industry_n have_v discover_v a_o secret_a for_o any_o particular_a distemper_n the_o people_n lie_v hold_v on_o it_o as_o of_o a_o public_a good_a and_o apply_v it_o indifferent_o to_o all_o sort_n of_o evil_n and_o if_o on_o some_o occasion_n it_o succeed_v not_o as_o it_o must_v unavoidable_o come_v to_o pass_v it_o be_v cry_v down_o with_o as_o much_o zeal_n and_o precipitance_n as_o it_o be_v bring_v in_o vogue_n this_o be_v the_o fortune_n of_o all_o the_o new_a febrifuge_n have_v see_v wonderful_a effect_n of_o they_o in_o some_o kind_n of_o fever_n man_n take_v they_o for_o universal_a remedy_n but_o so_o soon_o as_o they_o find_v they_o produce_v bad_a consequence_n in_o other_o for_o which_o they_o be_v not_o proper_a it_o be_v then_o general_o conclude_v that_o it_o be_v dangerous_a to_o make_v use_n of_o they_o for_o this_o reason_n that_o all_o scruple_n may_v be_v remove_v which_o people_n may_v frame_v to_o themselves_o in_o the_o use_n of_o this_o febrifuge_n i_o have_v think_v it_o pertinent_a careful_o to_o engage_v into_o the_o nature_n of_o fever_n and_o to_o mark_v their_o difference_n to_o observe_v those_o which_o be_v submit_v to_o this_o remedy_n and_o those_o to_o which_o it_o may_v prove_v prejudicial_a and_o last_o to_o prove_v with_o how_o much_o usefulness_n it_o may_v be_v employ_v when_o that_o be_v do_v with_o all_o care_n and_o necessary_a circumspection_n two_o motion_n be_v to_o be_v conceive_v in_o the_o blood_n that_o of_o the_o whole_a which_o be_v the_o circulation_n and_o another_o of_o the_o part_n proceed_v from_o its_o liquidity_n a_o fever_n be_v a_o fermentation_n of_o the_o blood_n fermentation_n be_v a_o irregular_a motion_n of_o the_o insensible_a part_n motus_fw-la intestinus_fw-la partium_fw-la insensibilium_fw-la we_o must_v look_v into_o the_o cause_n of_o the_o regular_a motion_n of_o this_o liquid_a body_n that_o by_o the_o rule_n of_o contrary_n we_o may_v discover_v those_o of_o the_o irregular_a motion_n there_o be_v two_o cause_n that_o maintain_v uniformity_n in_o the_o motion_n of_o the_o blood_n 1._o it_o be_v quantity_n and_o the_o constant_o equal_a force_n of_o the_o spirit_n which_o be_v the_o immediate_a mover_n and_o impulser_n of_o all_o the_o part_n that_o compose_v this_o liquid_a mass_n 2._o the_o just_a proportion_n of_o the_o same_o part_n as_o well_o in_o their_o quantity_n and_o quality_n as_o in_o their_o situation_n that_o be_v to_o say_v when_o the_o sulphureous_a acide_fw-la watery_a and_o earthy_a corpuscle_n be_v not_o only_o in_o a_o laudable_a proportion_n as_o to_o quanty_a but_o likewise_o be_v so_o well_o adjust_v and_o unite_v together_o that_o they_o no_o way_n annoy_v one_o another_o and_o be_v move_v by_o the_o spirit_n or_o celestial_a matter_n that_o animate_v they_o in_o a_o regular_a and_o uniform_a motion_n as_o long_o as_o thing_n be_v thus_o it_o may_v be_v say_v that_o the_o blood_n be_v in_o its_o natural_a state_n of_o health_n and_o to_o that_o end_n the_o author_n of_o nature_n have_v not_o only_o make_v our_o body_n transpirable_a thereby_o to_o give_v vent_n to_o the_o too_o great_a quantity_n of_o spirit_n but_o have_v also_o put_v in_o different_a place_n bowel_n and_o percolatory_n design_v to_o filtrate_a the_o superfluous_a and_o exceed_a part_n which_o may_v trouble_v the_o purety_n of_o that_o liquor_n from_o thence_o it_o may_v infer_v that_o there_o be_v two_o immediate_a cause_n of_o the_o fermentation_n of_o the_o blood_n the_o first_o be_v the_o too_o great_a quantity_n or_o the_o tor_z great_a motion_n of_o the_o spirit_n which_o may_v be_v excite_v by_o the_o heat_n of_o the_o sun_n violent_a exercise_n watch_v fast_a hot_a and_o spirituous_a nourishment_n and_o the_o passion_n and_o perturbation_n of_o the_o mind_n and_o from_o thence_o it_o be_v that_o all_o fever_n ephemerae_fw-la or_o of_o one_o day_n continuance_n and_o simple_a synoche_n which_o be_v the_o slight_a of_o all_o and_o may_v be_v cure_v by_o transpiration_n alone_o do_v arise_v the_o second_o be_v the_o mixture_n of_o irregular_a and_o fermentative_a corpuscle_n rerum_fw-la non_fw-la miscibilium_fw-la mixtio_fw-la which_o confound_v the_o order_n and_o alliance_n of_o the_o part_n of_o the_o blood_n raise_v a_o sedition_n there_o and_o deprave_v its_o motion_n and_o of_o these_o body_n some_o only_o raise_v a_o simple_a fermentation_n which_o at_o length_n may_v be_v govern_v and_o subdue_v by_o nature_n and_o the_o other_o being_n more_o malignant_a and_o venomous_a cause_n coagulation_n dissolution_n and_o colliguation_n in_o the_o mass_n of_o blood_n and_o can_v in_o no_o manner_n be_v correct_v from_o the_o former_a of_o these_o proceed_v all_o intermittent_a erratic_a and_o continue_a fever_n which_o be_v call_v subintrant_fw-la and_o from_o the_o other_o spring_n burn_v pestilential_a malignant_a and_o spot_a fever_n it_o be_v now_o to_o be_v consider_v in_o what_o part_n of_o our_o body_n and_o how_o these_o humour_n be_v produce_v though_o i_o have_v say_v that_o there_o be_v part_n viscera_fw-la appoint_v for_o the_o separation_n of_o the_o superfluity_n of_o the_o blood_n yet_o see_v they_o do_v not_o always_o discharge_v their_o function_n aright_o either_o through_o a_o fault_n in_o themselves_o or_o through_o the_o too_o great_a abundance_n of_o the_o same_o superfluity_n the_o same_o be_v hurry_v away_o by_o the_o rapidity_n of_o the_o circulation_n as_o filth_n be_v carry_v away_o by_o the_o impetuous_a current_n of_o a_o river_n but_o in_o the_o same_o manner_n as_o there_o happen_v a_o turn_n in_o that_o river_n where_o the_o water_n be_v still_a and_o where_o all_o that_o filth_n turn_v slow_o with_o the_o current_n stop_v so_o these_o heterogeneous_a body_n turn_v aside_o by_o the_o coeliack_a artery_n into_o the_o branch_n of_o the_o vena_fw-la porta_n where_o the_o blood_n circulate_v more_o slow_o and_o which_o for_o that_o reason_n may_v be_v compare_v to_o a_o lake_n or_o stand_a pool_n of_o water_n in_o respect_n of_o the_o other_o vessel_n there_o it_o be_v where_o want_v
their_o former_a agitation_n they_o have_v the_o mean_n of_o fasten_v and_o unite_n together_o to_o produce_v obstruction_n which_o be_v the_o primitive_a cause_n of_o all_o fever_n of_o the_o second_o order_n and_o sometime_o but_o seldom_o of_o those_o of_o the_o three_o as_o i_o shall_v now_o illustrate_v the_o blood_n can_v be_v long_o stop_v in_o a_o place_n without_o be_v exasperate_v and_o grow_v eager_a the_o spirit_n which_o be_v constant_o in_o motion_n fly_v away_o and_o carry_v with_o they_o first_o the_o more_o volatile_a part_n than_o the_o sulphureous_a which_o blunt_a and_o edge_n of_o the_o salt_n and_o keep_v they_o as_o in_o fetter_n which_o be_v the_o cause_n that_o these_o body_n have_v now_o nothing_o to_o stop_v their_o activity_n break_v off_o and_o diffuse_v themselves_o through_o the_o mass_n of_o blood_n to_o raise_v and_o ferment_n it_o until_o that_o be_v disperse_v and_o dissolve_v in_o the_o serosity_n they_o be_v expel_v by_o the_o ordinary_a way_n or_o otherways_o do_v so_o adjust_a and_o accommodate_v themselves_o with_o the_o other_o part_n that_o they_o disturb_v their_o alliance_n and_o motion_n no_o more_o there_o be_v nothing_o in_o fever_n but_o may_v be_v explain_v by_o this_o system_a the_o obstruction_n and_o the_o ferment_n which_o remain_v in_o that_o part_n which_o be_v call_v the_o focus_n make_v the_o periodick_n fit_v and_o paroxysm_n which_o be_v sometime_o quick_a and_o sometime_o slow_a according_a as_o the_o exasperate_v humour_n be_v more_o gross_a or_o more_o subtle_a the_o duplicity_n of_o focus_n or_o magazine_n make_v the_o double_a intermittent_a fever_n in_o a_o word_n there_o happen_v sometime_o so_o many_o of_o these_o nest_n that_o give_v no_o respite_n they_o cause_v continue_v fever_n which_o may_v be_v call_v subintrant_n but_o it_o sometime_o happen_v that_o these_o acid_a salt_n whether_o through_o their_o their_z too_o long_a continuance_n in_o a_o place_n or_o by_o a_o excessive_a heat_n of_o the_o entrails_n acquire_v a_o pretty_a violent_a degree_n of_o corrosion_n and_o be_v exalt_v to_o that_o height_n as_o to_o become_v venomous_a enough_o for_o spoil_v and_o whole_o ruine_v all_o the_o oeconomy_n of_o the_o blood_n and_o cause_v those_o fever_n which_o by_o a_o general_a name_n be_v call_v malignant_a but_o since_o the_o more_o common_a cause_n of_o these_o fever_n be_v vrsenical_a salt_n diffuse_v through_o the_o air_n which_o we_o breathe_v or_o lurk_v in_o the_o food_n we_o eat_v and_o that_o it_o be_v rare_a that_o our_o natural_a heat_n which_o be_v mild_a shall_v produce_v in_o our_o body_n that_o which_o the_o most_o violent_a fire_n of_o chemist_n can_v hardly_o perform_v in_o their_o vessel_n i_o say_v it_o be_v the_o less_o ordinary_a cause_n of_o those_o kind_n of_o fever_n have_v lay_v down_o these_o principle_n i_o say_v that_o this_o remedy_n be_v useless_a for_o the_o first_o and_o dangerous_a for_o the_o three_o kind_n of_o fever_n useless_a for_o the_o first_o because_o they_o be_v common_o cure_v of_o themselves_o and_o dangerous_a for_o the_o three_o because_o a_o venomous_a body_n and_o such_o as_o in_o no_o way_n can_v be_v subdue_v nor_o correct_v ought_v never_o to_o be_v fix_v on_o the_o contrary_a it_o ought_v with_o all_o expedition_n to_o be_v drive_v out_o by_o sweat_n or_o by_o other_o way_n of_o evacuation_n but_o i_o maintain_v that_o this_o remedy_n answer_v all_o the_o indication_n that_o we_o can_v have_v for_o the_o cure_n of_o those_o of_o the_o second_o order_n the_o explication_n which_o i_o have_v give_v of_o these_o fever_n which_o by_o a_o general_a name_n may_v be_v call_v intermittent_a furnish_v i_o with_o four_o indication_n for_o their_o cure_n 1._o to_o stop_v the_o fermentation_n of_o the_o blood_n 2._o to_o fix_v and_o correct_v the_o acid_n which_o be_v the_o cause_n of_o it_o 3._o to_o dissolve_v attenuate_v and_o drive_v out_o by_o the_o ordinary_a way_n of_o evacuation_n the_o gross_a humour_n that_o make_v obstruction_n 4._o and_o last_o to_o repair_v the_o loss_n of_o the_o sulphureous_a and_o unctuous_a corpuscle_n which_o sweeten_v the_o blood_n and_o which_o be_v evaporate_v by_o its_o offervescencie_n 1._o the_o feverish_a ebullition_n of_o the_o blood_n be_v sufficient_o stop_v by_o the_o terrestrial_a and_o astringent_a part_n of_o the_o quinquina_fw-la or_o jesuit_n powder_n and_o by_o the_o lesser_a centaury_n and_o the_o opium_n that_o enter_v the_o composition_n of_o the_o treacle_n 2._o after_o so_o many_o fair_a experiment_n we_o have_v no_o cause_n to_o doubt_v but_o that_o the_o fix_a salt_n of_o the_o quinquina_fw-la be_v the_o true_a corrective_a of_o the_o fermentative_a acid_n of_o the_o fever_n 3._o of_o all_o the_o ingredient_n that_o enter_v the_o composition_n of_o treacle_n there_o be_v none_o but_o drive_v out_o by_o sweat_v and_o urine_n the_o impurity_n of_o the_o blood_n last_o we_o may_v be_v easy_o persuade_v that_o the_o lesser_a centaury_n be_v most_o proper_a for_o restore_v the_o sulphureous_a part_n of_o the_o blood_n which_o have_v be_v dissipate_v in_o the_o fermentation_n if_o we_o consider_v its_o wonderful_a virtue_n in_o consolidate_v of_o wound_n and_o if_o we_o observe_v that_o the_o reunite_a of_o separate_a part_n be_v only_o perform_v by_o a_o balsamic_a and_o unctuous_a sulphur_n wherewith_o that_o plant_n abound_v the_o wine_n that_o be_v give_v immediate_o after_o contribute_v much_o also_o to_o that_o effect_n especial_o when_o the_o activity_n of_o its_o spirit_n be_v check_v by_o the_o mixture_n of_o the_o plant_n in_o water_n which_o on_o this_o occasion_n i_o shall_v prefer_v before_o that_o of_o bugloss_n i_o pretend_v not_o for_o all_o this_o to_o exclude_v the_o general_a and_o common_a remedy_n of_o physic_n nay_o i_o maintain_v that_o in_o the_o begin_n once_o or_o twice_o blood-letting_a according_a to_o the_o strength_n and_o repletion_n of_o the_o patient_n be_v necessary_a as_o well_o for_o facilitate_v the_o circulation_n of_o the_o blood_n as_o for_o remedy_v the_o pain_n of_o the_o head_n and_o oppression_n that_o blood_n swell_v in_o the_o fermentation_n may_v cause_v in_o pass_v through_o the_o capillary_a vessel_n of_o the_o brain_n and_o lung_n this_o remedy_n be_v not_o to_o be_v give_v till_o first_o by_o a_o dissolution_n of_o cassia_n or_o catholicum_fw-la the_o excrement_n of_o the_o low_a region_n which_o may_v trouble_v its_o operation_n be_v evacuate_v and_o last_o see_v the_o blood_n like_o other_o liquor_n in_o their_o ebullition_n drive_v always_o towards_o the_o mesentery_n a_o great_a many_o impure_a and_o feculent_a part_n like_o a_o scum_n it_o be_v necessary_a in_o the_o declension_n of_o the_o evil_a to_o purge_v they_o out_o if_o one_o will_v prevent_v relapse_n and_o sometime_o more_o troublesome_a consequence_n see_v it_o appear_v by_o the_o remark_n of_o the_o king_n chief_a physician_n and_o by_o the_o forego_n reflection_n that_o opium_n may_v useful_o be_v add_v to_o the_o english_a remedy_n and_o other_o febrifuge_n of_o the_o same_o nature_n i_o make_v no_o doubt_n but_o that_o you_o will_v read_v with_o pleasure_n the_o natural_a history_n of_o that_o excellent_a medicine_n the_o history_n of_o opium_n opium_n by_o most_o of_o the_o eastern_a people_n be_v still_o name_v offium_fw-la in_o imitation_n of_o the_o greek_n who_o common_o change_v p._n into_o a_o f._n it_o be_v the_o thicken_a juice_n of_o the_o indian_a poppy_n garrias_fw-la du_fw-fr jardin_fw-fr say_v that_o these_o head_n be_v big_a enough_o to_o contain_v four_o ounce_n and_o a_o half_a our_o poppy_n yield_v also_o a_o juice_n which_o be_v thicken_v may_v pass_v for_o a_o kind_n of_o opium_n but_o it_o have_v not_o the_o efficacy_n of_o that_o which_o be_v bring_v from_o hot_a country_n the_o author_n of_o the_o poor_a man_n physician_n propose_v a_o very_a easy_a preparation_n of_o it_o he_o will_v have_v we_o pound_n the_o head_n of_o our_o poppy_n about_o the_o end_n of_o may_n than_o put_v they_o in_o digestion_n in_o white_a wine_n for_o the_o space_n of_o fifteen_o day_n and_o afterward_o by_o evaporation_n reduce_v the_o digest_v liquor_n into_o a_o due_a consistency_n the_o true_a indian_a opium_n come_v from_o the_o eastern_a country_n according_a to_o the_o testimony_n of_o garrias_fw-la du_fw-fr jardin_fw-fr and_o christopher_n de_fw-fr la_fw-fr coste_n the_o poppy_n from_o which_o it_o be_v take_v grow_v common_o enough_o in_o egypt_n and_o therefore_o merchand_n bring_v much_o of_o it_o from_o grand_a cairo_n this_o be_v in_o great_a esteem_n and_o be_v call_v thebaick_a opium_n not_o to_o mention_v the_o opium_n that_o may_v be_v make_v of_o the_o poppy_n of_o longuedoc_n and_o provence_n nor_o of_o that_o which_o be_v make_v in_o italy_n we_o may_v divide_v into_o three_o kind_n that_o which_o be_v bring_v we_o from_o the_o indies_n for_o there_o be_v one_o
powder_n for_o there_o be_v some_o droguist_n that_o infuse_v it_o entire_a and_o have_v by_o that_o mean_v extract_v the_o first_o tincture_n out_o of_o it_o for_o their_o own_o advantage_n sell_v it_o afterward_o at_o the_o same_o rate_n as_o if_o it_o have_v not_o lose_v his_o chief_a virtue_n hitherto_o the_o price_n of_o quinquina_fw-la or_o jesuit_n powder_n have_v be_v very_o various_a and_o uncertain_a when_o it_o be_v only_o in_o the_o hand_n of_o the_o jesuit_n it_o be_v sell_v at_o rome_n and_o paris_n for_o eight_o or_o nine_o shilling_n sterling_a the_o do_v which_o consist_v only_o of_o two_o drachm_n but_o so_o soon_o as_o droguist_n begin_v to_o trade_n in_o it_o it_o begin_v to_o fall_v in_o price_n so_o that_o three_o or_o four_o year_n ago_o the_o best_a may_v have_v be_v have_v for_o about_o forty_o shilling_n the_o pound_n weight_n but_o no_o soon_o begin_v the_o english_a remedy_n to_o be_v in_o vogue_n but_o man_n begin_v every_o where_o to_o make_v experiment_n with_o the_o bark_n of_o peru_n which_o much_o enhanse_v the_o value_n of_o it_o yet_o that_o be_v not_o all_o which_o raise_v it_o to_o the_o high_a price_n for_o sir_n robert_n talbot_n observe_v that_o febrifuges_n be_v prepare_v which_o come_v very_o near_o his_o own_o and_o fear_v least_o some_o body_n at_o length_n may_v discover_v it_o resolve_v to_o buy_v up_o all_o the_o quinquina_fw-la that_o he_o can_v find_v at_o paris_n and_o the_o other_o chief_a town_n of_o france_n and_o of_o england_n also_o the_o execution_n of_o this_o design_n make_v some_o noise_n several_a physician_n surgeon_n and_o apothecary_n think_v it_o concern_v they_o to_o make_v all_o haste_n to_o provide_v themselves_o and_o some_o that_o they_o may_v not_o be_v want_v in_o precaution_n cause_v a_o considerable_a quantity_n of_o the_o bark_n to_o be_v bring_v from_o rouen_n and_o bourdeaux_n so_o that_o mr._n audery_n and_o mr._n vilain_n the_o two_o most_o famous_a droguist_n in_o paris_n have_v sell_v all_o they_o have_v at_o the_o rate_n of_o about_o fifteen_o pound_v the_o poundweight_n and_o not_o be_v able_a to_o procure_v any_o more_o from_o any_o place_n for_o above_o a_o fortnight_n there_o be_v not_o a_o bit_n to_o be_v have_v at_o any_o droguist_n shop_n in_o paris_n nevertheless_o some_o small_a quantity_n come_v at_o length_n but_o it_o be_v hold_v up_o so_o dear_a that_o it_o be_v like_a to_o have_v go_v off_o at_o the_o rate_n of_o a_o hundred_o crown_n the_o poundweight_n since_o that_o time_n the_o merchant_n have_v import_v much_o from_o spain_n and_o portugal_n and_o the_o english_a remedy_n have_v lose_v the_o advantage_n of_o the_o mode_n the_o price_n of_o that_o commodity_n have_v fall_v daily_o in_o so_o much_o that_o at_o present_v it_o do_v not_o yield_v above_o four_o or_o five_o pound_n the_o poundweight_n and_o i_o make_v no_o doubt_n but_o that_o in_o a_o short_a time_n a_o fleet_n from_o the_o west-indies_n will_v make_v it_o much_o cheap_a among_o the_o author_n who_o i_o have_v name_v there_o be_v some_o who_o endeavour_v to_o explain_v the_o property_n of_o quinquina_fw-la or_o the_o jesuit_n powder_n according_a to_o the_o principle_n of_o the_o ancient_a medicine_n think_v it_o enough_o to_o say_v that_o it_o be_v hot_a and_o dry_a in_o the_o begin_n of_o the_o second_o degree_n and_o some_o other_o of_o the_o number_n of_o those_o who_o have_v introduce_v bad_a principle_n into_o the_o new-philosophy_n think_v to_o mend_v the_o matter_n by_o say_v that_o quinquina_fw-la as_o a_o alkali_n stop_v the_o motion_n of_o the_o acid_n which_o occasion_n the_o fever_n but_o that_o be_v to_o illustrate_v one_o obscurity_n by_o other_o that_o be_v far_o more_o obscure_a that_o we_o may_v give_v the_o world_n somewhat_o more_o satisfactory_a as_o to_o that_o point_n we_o must_v in_o the_o first_o place_n with_o willis_n take_v our_o measure_n from_o experience_n and_o allow_v with_o he_o that_o all_o thing_n which_o be_v actual_o bitter_a have_v great_a virtue_n in_o sift_v preternatural_a fermentation_n and_o upon_o that_o account_n it_o be_v that_o the_o root_n of_o gentian_n be_v heretofore_o in_o so_o great_a reputation_n for_o cure_v of_o quartan_a ague_n and_o that_o the_o flower_n of_o the_o lesser_a cantaury_n the_o root_n of_o contrayerva_n and_o serpentaria_fw-la the_o leaf_n of_o wormwood_n and_o chervil_a scammony_n and_o many_o other_o bitter_a drogue_n be_v real_o febrifuge_n though_o in_o virtue_n far_o inferior_a to_o the_o jesuit_n powder_n have_v lay_v down_o this_o from_o undoubted_a truth_n we_o must_v now_o inquire_v into_o the_o natural_a cause_n which_o produce_v bitterness_n in_o mix_a body_n now_o suppose_v as_o it_o be_v reasonable_a we_o shall_v that_o the_o true_a element_n of_o body_n be_v acid_a liquid_a fiery_a etherean_a and_o terrestrial_a corpuscle_n it_o will_v be_v a_o very_a easy_a matter_n to_o discover_v those_o cause_n for_o see_v all_o bitter_a thing_n penetrate_v the_o tongue_n in_o such_o a_o manner_n that_o they_o leave_v therein_o a_o sense_n of_o their_o action_n for_o a_o long_a time_n after_o and_o that_o of_o all_o the_o element_n none_o be_v so_o proper_a as_o acid_n to_o produce_v that_o effect_n we_o must_v conclude_v that_o they_o be_v predominant_a in_o mixt_n which_o have_v that_o taste_n but_o also_o since_o be_v mingle_v with_o many_o liquid_a corpuscle_n they_o produce_v only_o sharp_a and_o corrode_a liquor_n as_o the_o spirit_n of_o salt_n vitriol_n alum_n etc._n etc._n that_o be_v join_v to_o fiery_a corpuscle_n they_o make_v only_a caustic_n as_o corrosive_a sublimat_n the_o spirit_n of_o nitre_n cauteres_fw-la etc._n etc._n and_o that_o be_v in_o intimate_a conjunction_n with_o sulphurous_a and_o oily_a particle_n they_o only_o produce_v sweet_a mixt_n as_o honey_n sugar_n etc._n etc._n it_o follow_v that_o none_o but_o terrestrial_a corpuscle_n mingle_v with_o they_o in_o a_o proportionable_a quantity_n can_v produce_v a_o bitter_a taste_n and_o in_o effect_n the_o more_o of_o earth_n there_o be_v in_o salt_n the_o bitter_a it_o be_v and_o on_o the_o contrary_a the_o more_o it_o be_v refine_v and_o depurate_v the_o less_o bitter_a it_o be_v thus_o sea_n salt_n dissolve_v in_o a_o moist_a air_n and_o afterward_o filtrate_v through_o brown_a paper_n have_v no_o other_o taste_n than_o of_o a_o acid_a spirit_n though_o before_o that_o dissolution_n and_o filtration_n it_o be_v considerable_o bitter_a now_o since_o among_o the_o element_n that_o i_o have_v name_v the_o acid_n be_v heavy_a and_o by_o consequence_n the_o cold_a and_o that_o though_o the_o terrestrial_a be_v not_o so_o heavy_a as_o it_o nor_o yet_o as_o the_o liquid_a yet_o it_o be_v more_o ponderous_a than_o the_o fiery_a and_o ethereal_a we_o may_v say_v that_o it_o be_v temperate_a i_o mean_v of_o a_o quality_n equal_o distant_a from_o the_o two_o extreme_n and_o that_o so_o be_v with_o the_o acid_a predominant_a in_o a_o mix_a body_n the_o mix_a must_v certain_o be_v cool_v or_o at_o least_o proper_a to_o preserve_v the_o just_a temperament_n of_o our_o body_n but_o because_o there_o be_v no_o bitter_a thing_n make_v up_o sole_o of_o acid_n and_o terrestrial_a corpuscle_n and_o that_o there_o be_v some_o wherein_o either_o the_o fiery_a the_o ethereal_a or_o liquid_a particle_n be_v likewise_o in_o a_o considerable_a quantity_n so_o there_o be_v some_o more_o or_o less_o bitter_a and_o even_o more_o or_o less_o cool_a and_o temperate_a but_o if_o we_o mind_v the_o dryness_n of_o quinquina_fw-la and_o yet_o how_o unapt_a it_o be_v to_o take_v fire_n it_o will_v not_o be_v hard_a to_o conclude_v that_o the_o three_o element_n which_o i_o have_v name_v last_o enter_v but_o in_o a_o very_a small_a quantity_n into_o the_o composition_n thereof_o and_o that_o by_o consequence_n among_o all_o bittter_fw-ge mixt_n none_o can_v be_v of_o a_o more_o temperate_a quality_n than_o it_o from_o the_o principle_n which_o i_o have_v now_o lay_v down_o concern_v the_o nature_n of_o quinquina_fw-la all_o the_o other_o property_n thereof_o may_v be_v deduce_v for_o see_v its_o predominant_a part_n be_v the_o acid_n who_o property_n be_v to_o coagulate_v the_o more_o substantial_a liquor_n such_o as_o blood_n milk_n etc._n etc._n and_o the_o terrestrial_a which_o by_o absorb_v the_o humidity_n and_o unctuosity_n that_o relaxate_v the_o solid_a part_n do_v bind_v and_o strengthen_v they_o of_o necessity_n it_o must_v be_v styptic_a and_o astringent_a and_o it_o be_v in_o effect_n in_o these_o two_o quality_n principal_o that_o the_o rarity_n and_o wonderfulness_n of_o its_o operation_n do_v consist_v as_o i_o have_v make_v appear_v in_o former_a observation_n but_o it_o be_v not_o to_o be_v think_v as_o some_o have_v imagine_v that_o this_o property_n of_o bind_v render_v it_o so_o fixative_a as_o to_o keep_v within_o the_o febrifick_a
have_v be_v the_o inventor_n of_o it_o or_o that_o he_o have_v hit_v upon_o it_o by_o chance_n and_o it_o may_v be_v say_v that_o his_o boldness_n which_o will_v have_v be_v take_v for_o a_o criminal_a rashness_n in_o any_o but_o a_o empiric_n have_v not_o a_o little_a contribute_v to_o the_o knowledge_n which_o we_o have_v at_o present_a of_o its_o use_n and_o manner_n of_o application_n the_o most_o wonderful_a effect_n of_o this_o febrifuge_n appear_v in_o all_o intermittent_a fever_n which_o be_v its_o true_a object_n for_o it_o stop_v and_o in_o fine_a whole_o cure_v quotidian_n ague_n tertian_n double_a tertian_n quartan_n double_a and_o triple_a quartan_o and_o sometime_o also_o other_o kind_n of_o fever_n for_o there_o be_v some_o continue_a fever_n which_o have_v kind_n of_o intermission_n and_o regular_a paroxysm_n observable_a by_o some_o small_a cold_a in_o the_o extremity_n of_o the_o body_n or_o some_o horror_n and_o shiver_a betwixt_o the_o shoulder_n be_v cure_v by_o the_o specific_a almost_o as_o speedy_o and_o secure_o as_o the_o true_a intermittent_a fever_n and_o this_o happen_v often_o in_o respect_n of_o slow_a hectic_a fever_n accompany_v with_o a_o consumption_n such_o as_o child_n be_v common_o affect_v with_o because_o they_o have_v certain_a inequality_n of_o remission_n and_o augmentation_n which_o give_v ground_n to_o the_o remedy_n to_o exert_v its_o virtue_n to_o second_v the_o attempt_n of_o nature_n and_o by_o consequence_n to_o reduce_v the_o blood_n unto_o its_o former_a disposition_n and_o to_o restore_v the_o stomach_n to_o its_o natural_a strength_n so_o that_o for_o the_o future_a provide_v only_o good_a and_o well_o digest_v chyle_n it_o send_v a_o vivify_a humidity_n to_o all_o the_o part_n which_o correct_v their_o dryness_n and_o restore_v the_o lose_a plumpness_n and_o good_a habit_n of_o body_n it_o be_v nevertheless_o to_o be_v observe_v that_o since_o the_o matter_n of_o continue_a fever_n be_v diffuse_v through_o the_o whole_a mass_n of_o blood_n that_o herein_o it_o cause_v a_o corruption_n hard_a to_o be_v rectify_v and_o that_o it_o whole_o take_v up_o nature_n without_o give_v she_o any_o respite_n she_o can_v be_v in_o a_o condition_n to_o concur_v the_o with_o specific_a but_o till_o by_o blood_n let_v and_o purge_v the_o impure_a and_o heterogeneous_a matter_n be_v in_o some_o manner_n expulse_v the_o irritation_n of_o the_o spirin_v calm_v and_o the_o humour_n be_v in_o good_a enough_o temper_n to_o return_v into_o favour_n with_o nature_n without_o which_o the_o specific_a which_o do_v not_o always_o excite_v regular_a evacuation_n be_v not_o powerful_a enough_o to_o put_v a_o stop_n to_o the_o sedition_n and_o compose_v the_o disorder_n which_o be_v then_o in_o the_o great_a vessel_n and_o in_o all_o the_o other_o principle_n and_o more_o necessary_a part_n of_o the_o body_n for_o the_o better_a understanding_n of_o the_o abovementioned_a direction_n and_o observation_n i_o will_v have_v it_o remark_v that_o every_o thing_n that_o occasion_n a_o extraordinary_a agitation_n in_o the_o spirit_n humour_n and_o general_o in_o the_o liquid_a and_o fluid_a part_n of_o our_o body_n may_v be_v consider_v as_o the_o primitive_a cause_n of_o fever_n that_o be_v to_o say_v of_o those_o irregular_a motion_n which_o happen_v so_o often_o in_o the_o mass_n of_o blood_n but_o seem_v the_o same_o motion_n will_v be_v quick_o rectify_v by_o nature_n be_v they_o not_o keep_v in_o be_v by_o some_o permanent_a cause_n and_o that_o beside_o by_o discompose_v all_o the_o oeconomy_n of_o nature_n they_o corrupt_v the_o ferment_n that_o serve_v for_o digestion_n and_o by_o that_o mean_n render_v the_o chyle_n impure_a and_o of_o a_o bad_a quality_n the_o deprave_a chylification_n may_v be_v look_v upon_o as_o the_o immediate_a and_o antecedent_n cause_n of_o fever_n so_o that_o a_o remedy_n can_v true_o be_v a_o febrifuge_n unless_o all_o at_o once_o it_o correct_v both_o the_o bad_a disposition_n of_o stomach_n and_o of_o the_o ferment_n of_o which_o i_o have_v be_v speak_v and_o that_o be_v the_o proper_a effect_n of_o the_o english_a febrifuge_n for_o like_o the_o most_o part_n of_o bitter_a medicament_n it_o be_v very_o stomachical_a be_v proper_a to_o consume_v the_o superfluous_a humidity_n and_o to_o restore_v the_o bone_n of_o the_o relaxated_a fibre_n of_o the_o ventricle_n and_o by_o that_o mean_n to_o increase_v the_o diminish_v appetite_n and_o retrieve_v it_o when_o it_o be_v whole_o lose_v from_o whence_o depend_v the_o perfect_a digestion_n of_o the_o victual_n even_o of_o the_o most_o solid_a food_n i_o can_v tell_v if_o one_o may_v not_o affirm_v it_o to_o be_v also_o more_o cordial_a for_o beside_o that_o it_o re-establishes_a the_o scatter_a force_n of_o the_o body_n and_o the_o decay_a natural_a heat_n it_o fix_v the_o heterogeneous_a particle_n that_o cause_v the_o fermentation_n of_o the_o blood_n and_o rally_n and_o call_v together_o those_o which_o have_v be_v divide_v and_o scatter_v during_o its_o ebullition_n this_o augmentation_n of_o force_n and_o heat_n make_v it_o sometime_o appear_v as_o if_o this_o febrifuge_n do_v re-kindle_a the_o fever_n after_o the_o take_n of_o the_o first_o do_v but_o it_o only_o augment_v it_o that_o it_o may_v the_o better_o engage_v with_o it_o and_o that_o apparent_a disorder_n be_v the_o sure_a sign_n of_o its_o triumph_n for_o the_o more_o violent_a it_o render_v one_o fit_a the_o more_o we_o may_v be_v assure_v that_o it_o will_v not_o be_v follow_v by_o another_o many_o physician_n can_v conceive_v how_o this_o remedy_n which_o seem_v only_o to_o be_v fixative_a can_v radical_o cure_v fever_n and_o ague_n but_o it_o be_v to_o be_v observe_v that_o though_o it_o cause_v not_o always_o a_o sensible_a evacuation_n yet_o it_o so_o powerful_a second_v the_o inclination_n of_o nature_n that_o during_o its_o operation_n the_o heterogeneous_a impure_a or_o superfluous_a matter_n be_v most_o common_o force_v out_o to_o the_o superfice_n of_o the_o body_n to_o be_v evacuate_v by_o insensible_a transpiration_n and_o even_o very_a often_o by_o copious_a sweat_n as_o also_o it_o be_v sometime_o the_o occasion_n of_o a_o critical_a looseness_n of_o the_o belly_n and_o in_o many_o patient_n the_o way_n of_o the_o urine_n serve_v for_o so_o salutary_a a_o evacuation_n that_o it_o cure_v both_o together_o the_o quartan_a ague_n and_o the_o dropsy_n occasion_v by_o it_o furthermore_o though_o the_o most_o certain_a and_o regular_a operation_n of_o the_o english_a remedy_n be_v to_o stop_v the_o fit_n of_o intermittent_a fever_n yet_o the_o use_n of_o it_o be_v not_o to_o be_v think_v of_o dangerous_a consequence_n it_o cause_v no_o trouble_n in_o the_o oeconomy_n of_o nature_n be_v like_o other_o bitter_a temperate_a medicament_n incapable_a of_o make_v any_o bad_a impression_n on_o man_n body_n for_o the_o reunion_n that_o it_o make_v of_o the_o part_n of_o the_o blood_n always_o facilitate_v the_o expulsion_n of_o morbific_a cause_n and_o though_o they_o shall_v partly_o stay_v within_o after_o its_o operation_n yet_o by_o mean_n of_o it_o they_o be_v correct_v and_o reconcile_v to_o nature_n or_o at_o least_o by_o reiterated_a and_o continual_a digestion_n they_o be_v at_o length_n concoct_v ripen_v and_o dissipate_v observation_n of_o the_o king_n chief_a physician_n concern_v the_o practice_n of_o sir_n robert_n talbor_n in_o the_o prepation_n and_o distribution_n of_o his_o remedy_n the_o great_a secret_n of_o most_o of_o empiric_n consist_v only_o in_o disguise_v the_o the_o drug_n that_o they_o make_v use_v of_o for_o since_o they_o be_v the_o very_a same_o whereof_o physician_n know_v the_o nature_n and_o property_n they_o can_v not_o make_v they_o pass_v for_o secret_a remedy_n unless_o they_o affect_o give_v they_o a_o air_n of_o novelty_n thus_o do_v sir_n robert_n talbor_n in_o the_o preparation_n of_o the_o jesuit_n powder_n either_o to_o make_v it_o be_v believe_v that_o the_o virtue_n of_o his_o febrifuge_n do_v not_o depend_v on_o that_o book_n or_o to_o make_v it_o be_v think_v that_o he_o understand_v it_o much_o better_a than_o those_o that_o have_v make_v use_n of_o it_o before_o he_o for_o it_o be_v very_o ordinary_a with_o he_o to_o besprinkle_v fix_v drachm_n of_o red_a rose_n with_o two_o ounce_n of_o the_o juice_n of_o lemon_n and_o afterward_o to_o infuse_v they_o for_o the_o space_n of_o four_o hour_n in_o six_o pound_n of_o fountain_n water_n to_o make_v use_n of_o that_o infusion_n for_o the_o make_n of_o his_o remedy_n add_v thereunto_o eight_o ounce_n of_o quinquina_fw-la powder_v and_o besprinkle_v with_o four_o ounce_n of_o the_o juice_n of_o fennel_n root_n and_o put_v into_o infusion_n only_o for_o the_o space_n of_o twelve_o hour_n sometime_o instead_o of_o that_o juice_n he_o will_v employ_v the_o juice_n of_o smallage_n leave_v and_o at_o other_o time_n
i_o will_v have_v it_o observe_v in_o the_o first_o place_n that_o the_o continual_a emission_n of_o animal_n spirit_n into_o all_o the_o nerve_n and_o by_o consequence_n into_o those_o that_o constitute_v the_o organ_n of_o the_o sense_n produce_v that_o state_n of_o body_n which_o we_o call_v be_v awake_a and_o wherein_o the_o body_n be_v capable_a of_o all_o the_o function_n that_o depend_v on_o the_o will_n the_o dissipation_n of_o the_o same_o spirit_n and_o every_o thing_n that_o hinder_v their_o passage_n be_v the_o cause_n or_o sleep_n which_o may_v be_v define_v a_o disposition_n wherein_o the_o external_a sense_n be_v so_o dull_v that_o they_o be_v incapable_a of_o the_o perception_n which_o they_o give_v to_o the_o mind_n and_o wherein_o all_o the_o other_o part_n of_o the_o body_n be_v weaken_v relaxated_a and_o improper_a for_o those_o voluntary_a action_n to_o which_o nature_n have_v destine_v they_o 〈◊〉_d for_o such_o never_o sleep_v sound_n who_o have_v their_o eye_n open_a speak_v walk_z or_o perform_v those_o function_n asleep_a which_o seem_v to_o depend_v on_o the_o will_n since_o they_o suppose_v the_o swell_a strength_n and_o in_o a_o word_n the_o motion_n of_o the_o nerve_n which_o can_v only_o be_v refer_v to_o the_o motion_n of_o the_o spirit_n wherewith_o they_o be_v then_o possess_v this_o be_v suppose_v it_o will_v not_o be_v hard_a to_o conceive_v why_o one_o fall_v natural_o asleep_a after_o labour_n and_o travel_v and_o after_o long_o watch_v for_o see_v those_o thing_n dissipate_v many_o spirit_n they_o be_v at_o length_n too_o few_o to_o fill_v all_o the_o nerve_n to_o support_v the_o body_n and_o to_o render_v it_o fit_a for_o sansation_n and_o motion_n insomuch_o that_o it_o necessary_o remain_v as_o without_o motion_n and_o sense_n until_o the_o blood_n be_v depurate_v and_o subtilise_v by_o its_o continual_a circulation_n discharge_v into_o the_o brain_n a_o sufficient_a quantity_n of_o spirit_n to_o make_v up_o the_o loss_n 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contain_v opium_n in_o a_o great_a quantity_n it_o be_v say_v that_o if_o it_o be_v pure_a and_o without_o all_o falsification_n it_o will_v cause_v blindness_n but_o to_o prevent_v that_o there_o be_v no_o more_o require_v than_o only_o to_o give_v it_o in_o the_o necessary_a do_v for_o the_o effect_n which_o we_o expect_v from_o it_o beside_o the_o do_v wherein_o we_o give_v that_o which_o be_v bring_v to_o we_o be_v always_o proportionable_a to_o that_o i_o have_v be_v speak_v of_o it_o will_v follow_v that_o that_o accident_n shall_v happen_v to_o those_o to_o who_o it_o be_v give_v if_o it_o be_v true_a that_o it_o be_v capable_a to_o cause_v it_o to_o conclude_v they_o who_o pretend_v that_o it_o ought_v to_o be_v rank_v among_o poison_n shall_v confess_v that_o it_o kill_v not_o but_o when_o a_o bad_a use_n be_v make_v of_o it_o and_o that_o so_o there_o be_v no_o more_o poison_n in_o it_o than_o in_o the_o best_a medicine_n and_o i_o dare_v be_v bold_a to_o say_v that_o our_o very_a food_n of_o which_o bread_n be_v he_o most_o innocent_a be_v take_v without_o measure_n may_v cause_v a_o surfeit_n and_o mortal_a suffocation_n finis_fw-la