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they_o it_o be_v probable_a this_o may_v be_v do_v more_o easy_o here_o than_o in_o the_o corpus_fw-la callosum_fw-la it_o be_v true_a it_o must_v be_v grant_v that_o the_o artery_n be_v disseminated_a through_o all_o part_n of_o it_o even_o to_o the_o inmost_a otherwise_o they_o can_v neither_o receive_v due_a heat_n nor_o nourishment_n if_o at_o least_o nourishment_n come_v immediate_o from_o the_o blood_n to_o any_o part_n but_o the_o root_n of_o the_o nerval_a tree_n numerous_o disperse_v through_o the_o cortex_fw-la which_o vessel_n though_o penetrate_a ever_o so_o deep_a if_o they_o chance_v either_o to_o open_v be_v break_v or_o become_v relax_v whereby_o they_o may_v let_v go_v some_o of_o the_o substance_n they_o carry_v after_o the_o manner_n by_o and_o by_o to_o be_v allege_v it_o be_v obvious_a must_v soon_o supply_v the_o matter_n of_o a_o considerable_a inundation_n if_o i_o may_v so_o call_v it_o of_o the_o blood_n or_o those_o
blood_n even_o in_o the_o vessel_n for_o any_o considerable_a time_n necessary_o kill_v both_o from_o what_o appear_v upon_o dissection_n not_o only_o wepfer_v before_o mention_v but_o other_o observation_n evince_v it_o and_o i_o myself_o happen_v to_o observe_v the_o same_o in_o the_o dissection_n of_o a_o very_a worthy_a lady_n the_o lady_n pakington_n the_o relation_n whereof_o be_v publish_v in_o the_o philosophical_a transaction_n num._n 173._o a._n d._n 1675._o as_o also_o in_o regard_n it_o seem_v difficult_a to_o make_v out_o how_o from_o a_o slow_a congestion_n if_o viscous_a matter_n be_v the_o cause_n or_o from_o a_o exudation_n of_o serum_fw-la the_o diffusion_n whereof_o though_o somewhat_o more_o speedy_a than_o in_o the_o supposition_n of_o viscosity_n be_v yet_o comparative_o slow_a to_o the_o sodainness_n of_o the_o invasion_n much_o more_o from_o so_o very_o slow_a a_o congestion_n as_o must_v produce_v a_o fleshy_a substance_n as_o the_o polypus_fw-la be_v unless_o on_o the_o occasion_n of_o its_o dislodging_n even_o now_o mention_v all_o the_o animal_n function_n from_o a_o perfect_a exercise_n of_o they_o as_o be_v most_o usual_o observable_a shall_v so_o instantaneous_o be_v destroy_v whereas_o the_o effusion_n of_o the_o blood_n out_o of_o its_o vessel_n may_v rational_o yield_v a_o account_n of_o this_o defection_n with_o as_o great_a swiftness_n as_o can_v be_v imagine_v the_o blood_n as_o i_o say_v before_o once_o get_v out_o of_o its_o channel_n be_v propel_v by_o mean_n of_o the_o impulse_n from_o the_o heart_n so_o as_o to_o diffuse_v itself_o immediate_o over_o the_o whole_a substance_n of_o the_o brain_n so_o far_o as_o the_o invest_n membrane_n will_v permit_v and_o though_o only_o one_o lobe_n of_o it_o chance_v to_o be_v disaffect_v yet_o the_o commerce_n be_v break_v off_o betwixt_o the_o spirit_n in_o this_o and_o the_o rest_n it_o seem_v probable_a though_o from_o the_o disproportion_n of_o our_o organ_n to_o discern_v those_o 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invasion_n of_o the_o distemper_n as_o be_v before_o insinuate_v be_v owe_v to_o the_o vitiate_a organization_n of_o it_o and_o not_o all_o to_o the_o perluent_fw-la liquor_n for_o if_o it_o be_v firm_a in_o its_o tone_n and_o otherwise_o right_o constitute_v there_o be_v reason_n to_o suppose_v it_o may_v caeteris_fw-la paribus_fw-la much_o resist_v morbific_a impression_n whereas_o if_o it_o have_v be_v before_o weaken_v it_o be_v obvious_a it_o will_v easy_o yield_v to_o they_o we_o see_v in_o fever_n that_o the_o blood_n run_v rapid_o enough_o through_o it_o and_o in_o a_o anasarca_fw-la and_o cachectical_a habit_n the_o serum_fw-la make_v up_o much_o the_o great_a part_n of_o the_o blood_n which_o may_v therefore_o be_v presume_v apt_a to_o overflow_v that_o tender_a part_n so_o also_o it_o be_v observable_a that_o the_o blood_n many_o time_n appear_v extreme_o viscous_a as_o in_o pleurisy_n rheumatisme_n etc._n etc._n yet_o in_o none_o of_o these_o case_n ordinary_o be_v the_o person_n incline_v to_o apoplexy_n so_o that_o though_o the_o irregularity_n of_o the_o liquor_n may_v sometime_o occasion_v they_o without_o this_o predisposition_n oft_o he_o brain_n yet_o when_o it_o appear_v they_o invade_v more_o frequent_o than_o otherwise_o they_o use_v to_o do_v there_o seem_v considerable_a reason_n to_o suppose_v that_o it_o deflect_v some_o way_n or_o other_o in_o its_o organization_n from_o what_o be_v natural_a to_o it_o this_o defect_n i_o deny_v not_o may_v perhaps_o sometime_o consist_v in_o too_o great_a a_o closeness_n of_o its_o texture_n whereby_o a_o partial_a obstruction_n of_o its_o vessel_n may_v be_v make_v by_o degree_n from_o the_o adhesion_n of_o some_o viscouse_n matter_n deposit_v by_o little_a and_o little_a by_o the_o circulate_v blood_n about_o the_o capillary_a artery_n and_o so_o the_o blood_n behind_o come_v indeed_o only_o to_o be_v retard_v here_o whilst_o no_o disturbance_n happen_v to_o it_o but_o take_v its_o course_n to_o some_o other_o region_n of_o the_o body_n but_o if_o it_o once_o come_v to_o be_v more_o than_o ordinary_o exagitated_a it_o may_v become_v so_o determine_v in_o its_o motion_n as_o at_o last_o to_o flow_v impetuous_o hither_o too_o but_o not_o be_v able_a to_o get_v through_o its_o usual_a channel_n must_v produce_v the_o effect_n before_o suggest_v of_o a_o irruption_n into_o the_o substance_n of_o the_o brain_n but_o yet_o ordinary_o i_o conceive_v it_o depend_v upon_o too_o great_a laxity_n of_o it_o whereby_o when_o any_o forcible_a impulse_n happen_v it_o may_v too_o ready_o yield_v to_o it_o and_o so_o be_v sudden_o overwhelm_v this_o laxity_n may_v be_v consider_v to_o consist_v not_o only_o in_o a_o great_a inteneration_n of_o its_o substance_n than_o usual_a and_o thence_o its_o easiness_n to_o yield_v to_o the_o force_n of_o the_o impel_v blood_n to_o which_o in_o its_o due_a constitution_n it_o bear_v a_o proportion_n but_o likewise_o in_o the_o great_a openness_n of_o its_o pore_n than_o be_v natural_a though_o the_o fibre_n that_o constitute_v it_o have_v their_o due_a degree_n of_o firmness_n whereby_o it_o become_v capable_a of_o receive_v other_o and_o more_o bulky_a particle_n than_o usual_a as_o be_v consequential_a upon_o that_o texture_n so_o deprave_v which_o may_v possible_o as_o in_o too_o serous_a and_o acrimonious_a a_o dyscrasy_a of_o the_o blood_n proceed_v from_o the_o abrasion_n of_o some_o of_o the_o loose_a particle_n that_o constitute_v the_o habit_n of_o the_o part_n by_o the_o perluent_fw-la juice_n supply_v by_o such_o blood_n and_o i_o suppose_v may_v be_v the_o case_n of_o the_o lady_n before_o mention_v who_o be_v endue_v with_o a_o extraordinary_a acumen_n a_o great_a evidence_n of_o a_o exquisite_a constitution_n of_o the_o brain_n yet_o abound_v with_o exceed_o sharp_a substance_n in_o her_o blood_n or_o other_o liquor_n as_o many_o of_o her_o symptom_n declare_v which_o pore_n likewise_o may_v acquire_v other_o figure_n than_o be_v proper_a for_o they_o these_o concur_v particular_o to_o determine_v almost_o any_o of_o the_o secretion_n whether_o simple_a or_o mix_v that_o happen_v in_o our_o body_n so_o that_o when_o the_o brain_n happen_v to_o have_v its_o organization_n thus_o vitiate_v and_o the_o other_o cause_n concur_v a_o apoplexy_n may_v in_o probability_n easy_o enough_o be_v produce_v so_o that_o to_o recapitulate_v i_o conceive_v the_o part_n effect_v may_v either_o be_v the_o whole_a brain_n or_o any_o considerable_a part_n of_o it_o and_o either_o the_o cortical_a or_o medullar_n but_o especial_o or_o at_o lest_o first_o the_o cortical_a from_o whence_o the_o disaffect_v matter_n be_v transmit_v to_o the_o part_n of_o it_o which_o lie_v deep_o where_o the_o animal_n spirit_n principal_o exert_v themselves_o the_o nature_n of_o the_o distemper_n to_o consist_v in_o the_o sudden_a abolition_n of_o the_o due_a excrasie_n and_o distribution_n of_o they_o thence_o the_o immediate_a cause_n most_o usual_o when_o unavoidable_o fatal_a a_o effusion_n of_o blood_n out_o of_o its_o vessel_n upon_o the_o substance_n of_o the_o brain_n though_o i_o conceive_v a_o bare_a distension_n of_o the_o artery_n there_o may_v occasion_v it_o as_o also_o may_v perhaps_o a_o congestion_n of_o viscous_a or_o serous_a matter_n when_o it_o come_v to_o a_o considerable_a degree_n and_o become_v fresh_o excite_v or_o else_o polypous_a concretion_n or_o if_o we_o can_v suppose_v it_o any_o other_o obstruct_v matter_n deposit_v in_o it_o may_v at_o last_o produce_v it_o and_o the_o predisposition_n of_o the_o brain_n to_o it_o to_o consist_v usual_o in_o the_o more_o than_o ordinary_a laxity_n or_o openness_n of_o it_o these_o thing_n premise_v i_o consider_v to_o advance_v a_o little_a far_o towards_o the_o solution_n of_o the_o problem_n that_o whatsoever_o either_o 1_o sy_n cause_v a_o congestion_n of_o blood_n or_o 2_o dly_a otherwise_o so_o indispose_v it_o that_o it_o can_v ready_o and_o
considerable_a number_n of_o its_o particle_n at_o once_o and_o so_o undergo_v a_o strong_a impression_n which_o may_v easy_o enough_o be_v conceive_v to_o be_v propagate_v to_o the_o brain_n partly_o by_o disturb_v their_o regular_a tonic_a motion_n which_o must_v from_o their_o tensity_n be_v continue_v up_o to_o their_o original_n partly_o by_o the_o ingress_n of_o too_o many_o of_o the_o lancinate_a particle_n of_o it_o into_o they_o which_o beside_o the_o fix_v or_o dissipate_v the_o animal_n spirit_n which_o i_o conceive_v to_o be_v much_o of_o the_o nature_n of_o volatill_a salt_n may_v disorder_v the_o tone_n of_o these_o nerve_n first_o and_o then_o by_o the_o continuance_n of_o the_o impulse_n of_o those_o behind_o which_o have_v the_o same_o ground_n to_o attempt_v a_o entrance_n that_o of_o the_o brain_n itself_o which_o be_v more_o tender_a than_o the_o nerve_n must_v therefore_o when_o the_o cause_n of_o the_o disaffection_n reach_v it_o be_v proportional_o injure_v a_o 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cavity_n therefore_o be_v to_o be_v fill_v in_o proportion_n to_o that_o dilatation_n it_o must_v happen_v that_o that_o portion_n of_o air_n that_o do_v it_o must_v have_v brisk_a agitation_n than_o the_o rest_n of_o its_o mass_n and_o make_v impression_n according_o this_o pressure_n i_o say_v may_v prove_v chief_o injurious_a to_o the_o brain_n by_o its_o act_n on_o the_o nerve_n in_o the_o ear_n because_o they_o be_v terminate_v at_o a_o cavity_n which_o be_v still_o keep_v warm_a than_o the_o rest_n by_o the_o steame_n continual_o exude_v from_o every_o side_n of_o it_o and_o for_o some_o time_n somewhat_o detain_v there_o must_v therefore_o be_v more_o open_a and_o consequent_o more_o liable_a to_o injury_n if_o a_o extraordinary_a occasion_n happen_v such_o as_o i_o be_o instance_v in_o to_o make_v a_o impression_n on_o they_o and_o this_o must_v happen_v rather_o to_o tender_a body_n and_o those_o who_o accustom_v themselves_o to_o keep_v much_o within_o door_n than_o to_o the_o more_o robu_v who_o employment_n expose_v they_o much_o to_o the_o air_n at_o all_o season_n both_o on_o the_o score_n of_o the_o comparative_a flaccidity_n of_o all_o part_n in_o they_o and_o the_o defect_n of_o a_o due_a digestion_n in_o their_o blood_n and_o other_o liquor_n through_o want_n of_o due_a exercise_n which_o must_v dispose_v they_o to_o be_v put_v into_o confusion_n when_o violent_a cause_n come_v to_o excite_v it_o and_o experience_n show_v that_o such_o person_n of_o all_o other_o be_v most_o obnoxious_a to_o the_o alteration_n of_o the_o air._n so_o that_o the_o manner_n of_o this_o action_n seem_v to_o consist_v in_o the_o penetration_n make_v by_o the_o nitrous_a particle_n principal_o of_o the_o air_n upon_o the_o fibre_n of_o the_o brain_n for_o that_o as_o well_o as_o all_o other_o solid_a part_n must_v consist_v of_o fibres_n which_o thereby_o undergo_v some_o however_o small_a solution_n of_o continuity_n and_o either_o the_o little_a cavity_n of_o those_o fibre_n for_o i_o think_v the_o aeconomy_n of_o our_o body_n can_v hardly_o be_v mechanical_o make_v out_o without_o suppose_v they_o all_o to_o be_v vessel_n though_o our_o sensory_n can_v determine_v it_o become_v straighten_a or_o their_o side_n perforate_v on_o the_o account_n of_o either_o of_o which_o they_o can_v due_o either_o receive_v or_o retain_v and_o consequent_o not_o regular_o transmit_v the_o substance_n destine_v to_o each_o part_n which_o be_v to_o be_v respective_o supply_v by_o they_o in_o that_o continuity_n due_a confirmation_n &_o repletion_n of_o they_o i_o suppose_v the_o tone_n of_o the_o part_n to_o consist_v and_o therefore_o when_o any_o thing_n pervert_v any_o of_o these_o requisite_n to_o it_o as_o in_o our_o present_a case_n all_o the_o consequence_n emergent_a from_o the_o impulse_n of_o the_o blood_n or_o other_o liquor_n disturb_v in_o their_o motion_n may_v be_v expect_v now_o such_o a_o atony_n happen_v to_o be_v in_o so_o very_o tender_a a_o part_n as_o the_o brain_n can_v therefore_o easy_o be_v rectify_v but_o may_v continue_v much_o long_o than_o if_o it_o happen_v to_o other_o part_n who_o fibre_n be_v strong_a and_o function_n few_o must_v on_o both_o score_n caeteris_fw-la paribus_fw-la soon_o and_o more_o easy_o return_v to_o their_o natural_a constitution_n and_o not_o only_o the_o reason_n of_o the_o thing_n but_o daily_a experience_n show_v it_o that_o whereas_o most_o other_a part_n of_o our_o body_n have_v once_o receive_v any_o injurious_a impression_n as_o by_o fall_v blow_n etc._n etc._n do_v after_o fit_a remedy_n use_v return_v to_o their_o due_a tone_n quick_o the_o cause_n once_o remove_v the_o brain_n on_o the_o contrary_a long_o retain_v its_o weakness_n if_o once_o injure_v though_o for_o the_o present_a relieve_v in_o some_o degree_n as_o for_o instance_n those_o that_o have_v have_v a_o apoplectic_a fit_n once_o do_v many_o time_n on_o whatsoever_o light_a occasion_n either_o find_v a_o return_n 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introduce_v and_o also_o such_o a_o debility_n may_v be_v impress_v on_o the_o tone_n of_o the_o brain_n that_o they_o may_v much_o more_o ready_o invade_v if_o the_o ordinary_a though_o at_o other_o time_n innoxious_a for_o the_o most_o part_n at_o least_o occasion_n happen_v to_o bring_v these_o disposition_n to_o effect_v now_o it_o be_v know_v that_o the_o winter_n of_o the_o year_n 1683_o from_o which_o i_o date_n my_o aera_fw-la of_o this_o frequency_n of_o apoplexy_n be_v so_o intense_o cold_a and_o that_o cold_a of_o so_o long_a continuance_n that_o no_o man_n memory_n live_v can_v supply_v he_o with_o a_o parallel_n year_n and_o there_o be_v no_o need_n to_o repair_v to_o the_o northern_a region_n to_o make_v experiment_n of_o freeze_a spirituous_a liquor_n in_o order_n to_o find_v out_o the_o extent_n of_o this_o effect_n of_o it_o since_o which_o time_n it_o may_v be_v observe_v that_o this_o distemper_n have_v be_v so_o rife_o but_o since_o it_o be_v requisite_a the_o 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