Selected quad for the lemma: cause_n

Word A	Word B	Word C	Word D	Occurrence	Frequency Band	MI	MI Band	Prominent
cause_n	body_n	disease_n	fever_n	1,543	5	9.5930	5	false

Text snippets containing the quad

ID	Title	Author	Corrected Date of Publication (TCP Date of Publication)	STC	Words	Pages
A30711	Two treatises the one medical, Of the gout and its nature more narrowly search'd into than hitherto, together with a new way of discharging the same / by Herman Busschof ; the other partly chirurgical, partly medical containing Some observations and practices relating both to some extraordinary cases of women in travel, and to some other uncommon cases of diseases in both sexes by Henry Van Roonhuysen ... ; Englished out of Dutch by a careful hand.	Busschof, Hermann. Of the gout.; Busschof, Hermann. Of the gout and its nature more narrowly search'd into than hitherto, together with a new way of discharging the same.; Busschof, Hermann. Gout more narrowly searcht and found out, together with the certain cure thereof.; Busschof, Hermann. Podagra, nader als oyt nagevorst enytgevonden.	1676 (1676)	Wing B6257; ESTC R11109	43,328	152

disease_n do_v an._n not_o that_o the_o organ_n of_o motion_n be_v attack_v hurt_v or_o torment_v but_o only_o that_o the_o periostium_fw-la be_v put_v out_o of_o its_o natural_a posture_n which_o be_v manifest_a from_o hence_o that_o as_o soon_o as_o this_o membrane_n be_v restore_v to_o its_o natural_a state_n you_o can_v perceive_v the_o least_o defect_n in_o those_o organ_n qu._n why_o then_o do_v the_o pain_n increase_n and_o grow_v more_o violent_a upon_o touch_v or_o move_v the_o part_n affect_v an._n this_o come_v not_o to_o pass_v because_o that_o the_o organ_n of_o motion_n or_o their_o membrane_n do_v suffer_v but_o because_o that_o the_o membrane_n be_v already_o distend_v by_o the_o touch_n or_o motion_n thereof_o it_o come_v to_o suffer_v and_o to_o stretch_v a_o new_a whereupon_o new_a pain_n must_v follow_v chap._n x._o of_o the_o symptom_n of_o the_o gout_n qu._n forasmuch_o as_o there_o be_v find_v many_o and_o different_a symptom_n in_o the_o gout_n will_v it_o not_o be_v proper_a to_o make_v a_o distinction_n between_o they_o thereby_o to_o come_v to_o the_o true_a knowledge_n of_o they_o an._n you_o will_v do_v very_o well_o to_o distinguish_v first_o the_o symptom_n in_o general_a from_o the_o disease_n itself_o and_o then_o to_o make_v a_o distinction_n between_o the_o symptom_n themselves_o qu._n what_o distinction_n be_v there_o to_o be_v make_v between_o the_o symptom_n of_o the_o gout_n an._n this_o that_o the_o symptom_n that_o arise_v and_o vanish_v with_o the_o disease_n be_v to_o be_v distinguish_v from_o those_o that_o be_v breed_v not_o from_o the_o gout_n but_o from_o the_o symptom_n of_o the_o gout_n qu._n which_o be_v the_o symptom_n that_o do_v immediate_o accompany_v the_o gout_n and_o be_v bear_v and_o die_v with_o it_o an._n of_o these_o there_o be_v but_o two_o already_o speak_v of_o viz._n the_o vitiate_a motion_n and_o the_o violent_a pain_n these_o come_v and_o go_v away_o with_o the_o disease_n follow_v the_o gout_n as_o a_o shadow_n do_v a_o body_n qu._n which_o of_o these_o two_o symptom_n be_v the_o chief_a and_o most_o grievous_a an._n the_o pain_n which_o be_v not_o the_o disease_n itself_o or_o the_o cause_n of_o the_o gout_n as_o have_v be_v already_o say_v nor_o yet_o be_v it_o a_o simple_a symptom_n in_o regard_n it_o be_v a_o cause_n of_o other_o symptom_n especial_o when_o it_o be_v violent_a qu._n what_o symptom_n be_v occasion_v or_o rather_o cause_v thereby_o an._n inflammation_n fever_n faint_n sleepiness_n loss_n of_o strength_n afflux_n of_o humour_n qu._n be_v it_o certain_a that_o all_o these_o six_o accident_n be_v cause_v by_o the_o rage_a pain_n of_o the_o gout_n an._n dr._n paul_n barbette_v reckon_v they_o all_o among_o the_o effect_n of_o the_o gouty_a pain_n when_o he_o treat_v of_o the_o symptom_n of_o wound_n in_o his_o chirurgery_n p._n 165._o of_o his_o dutch_a edition_n beside_o that_o it_o be_v manifest_a that_o most_o of_o these_o do_v then_o first_o appear_v when_o the_o pain_n grow_v violent_a and_o disappear_v with_o the_o diminution_n and_o cease_v of_o the_o pain_n qu._n whence_o come_v it_o that_o these_o symptom_n that_o be_v cause_v by_o the_o gout_n not_o only_o in_o divers_a patient_n but_o also_o in_o the_o same_o show_v themselves_o at_o one_o time_n more_o than_o another_o and_o differ_v so_o much_o from_o one_o another_o an._n it_o come_v from_o the_o great_a or_o lesser_a intenseness_n of_o the_o efficient_a cause_n the_o pain_n which_o receive_v its_o degree_n from_o the_o quality_n and_o quantity_n of_o the_o gouty_a matter_n for_o the_o more_o malign_a and_o abound_a the_o damp_n be_v the_o more_o grievous_a also_o be_v not_o only_o the_o proper_a symptom_n but_o also_o these_o accident_n of_o the_o gout_n qu._n do_v the_o rage_a pain_n excite_v in_o all_o gouty_a person_n these_o symptom_n all_o together_o and_o at_o once_o an._n not_o so_o for_o in_o body_n that_o have_v but_o little_a serosity_n in_o the_o blood_n the_o first_o five_o symptom_n do_v appear_v but_o not_o at_o all_o or_o very_o seldom_o the_o six_o and_o last_o which_o be_v the_o afflux_n of_o humour_n in_o other_o who_o abound_v in_o that_o serosity_n the_o afflux_n of_o moisture_n will_v be_v perceive_v first_o of_o all_o and_o often_o without_o inflammation_n again_o when_o the_o gouty_a matter_n lurk_v deep_a as_o in_o the_o sciatica_n and_o in_o the_o gout_n of_o the_o shoulder_n you_o be_v not_o then_o to_o reckon_v upon_o the_o change_n of_o colour_n and_o the_o afflux_n qu._n that_o rage_a pain_n do_v cause_n inflammation_n be_v easy_o understand_v but_o how_o do_v they_o produce_v fever_n faint_n sleepiness_n and_o loss_n of_o strength_n an._n the_o intolerable_a pain_n draw_v to_o the_o heart_n cause_v there_o a_o fever_n and_o faint_v and_o pass_v to_o the_o brain_n produce_v there_o wake_v whence_o must_v necessary_o follow_v loss_n of_o strength_n chap._n xi_o of_o the_o external_a serous_a tumour_n which_o often_o manifest_v itself_o in_o the_o gout_n qu._n be_v it_o worth_a while_n to_o treat_v somewhat_o more_o large_o of_o this_o tumour_n than_o of_o the_o other_o symptom_n cause_v by_o the_o pain_n an._n it_o be_v very_o necessary_a because_o by_o this_o symptom_n many_o learned_a man_n have_v be_v so_o mislead_v as_o to_o take_v it_o for_o the_o gout-breeding_a matter_n itself_o or_o at_o least_o not_o to_o distinguish_v it_o from_o the_o sickness_n itself_o whence_o as_o from_o a_o fruitful_a soil_n have_v spring_v so_o many_o error_n about_o the_o gout_n and_o especial_o about_o the_o proxime_fw-la cause_n thereof_o yea_o this_o be_v the_o only_a cause_n that_o so_o many_o physician_n and_o chirurgeon_n be_v so_o much_o wed_v to_o the_o notion_n of_o humour_n that_o they_o dare_v almost_o take_v it_o for_o grant_v that_o the_o gout_n can_v be_v without_o this_o swell_a and_o afflux_n of_o humour_n insomuch_o that_o if_o they_o meet_v with_o any_o gouty_a person_n in_o who_o they_o can_v find_v this_o swell_a or_o change_n of_o colour_n although_o they_o find_v great_a pain_n they_o will_v rather_o discard_v they_o out_o of_o the_o number_n of_o the_o gouty_a than_o acknowledge_v that_o sometime_o there_o be_v no_o humour_n at_o all_o accompany_v the_o gout_n qu._n but_o since_o the_o affluxed_a humour_n which_o breed_v the_o external_a swell_n be_v neither_o in_o whole_a nor_o in_o part_n the_o cause_n of_o the_o gout_n what_o shall_v we_o make_v of_o that_o tumour_n and_o its_o matter_n an._n it_o be_v a_o symptom_n which_o be_v no_o inseparable_a companion_n of_o the_o gout_n yea_o never_a begin_v and_o seldom_o end_v with_o that_o disease_n which_o i_o think_v i_o can_v so_o plain_o make_v out_o as_o that_o the_o most_o ordinary_a capacity_n shall_v understand_v it_o to_o be_v so_o qu._n do_v then_o this_o serous_a swell_v not_o always_o accompany_v the_o gout_n as_o a_o inseparable_a symptom_n an._n no_o for_o beside_o that_o some_o gouty_a person_n seldom_o or_o never_o perceive_v this_o tumour_n cause_v by_o affluxed_a humour_n as_o i_o have_v experience_v and_o many_o writer_n must_v witness_v common_o there_o be_v no_o affluxed_a humour_n find_v in_o the_o sciatica_n qu._n but_o do_v this_o swell_v never_o begin_v with_o the_o gout_n an._n it_o be_v never_o perceive_v in_o the_o begin_n of_o the_o gout_n for_o though_o in_o many_o patient_n this_o tumour_n very_o soon_o follow_v upon_o the_o gout_n yet_o if_o it_o be_v well_o observe_v it_o be_v never_o of_o the_o same_o age_n with_o the_o gouty_a tumour_n which_o in_o order_n of_o time_n always_o precede_v it_o yea_o if_o care_n be_v have_v its_o birth_n may_v sometime_o be_v altogether_o prevent_v by_o be_v timely_a ready_a to_o evaporate_v this_o dolorifick_a damp_n by_o a_o speedy_a application_n of_o my_o matchless_a discharge_n remedy_n as_o i_o have_v often_o experiment_v on_o myself_o and_o shall_v further_o teach_v in_o the_o second_o part_n treat_v of_o the_o cure_n of_o the_o gout_n qu._n but_o as_o this_o symptom_n never_o begin_v with_o the_o disease_n do_v it_o neither_o end_n always_o with_o it_o as_o other_o symptom_n do_v an._n no_o this_o symptom_n alone_o survive_v the_o gout_n yea_o the_o cause_n whence_o it_o rise_v end_v not_o with_o it_o for_o as_o for_o the_o most_o part_n it_o first_o appear_v when_o the_o sickness_n be_v at_o its_o height_n and_o the_o pain_n rage_v so_o it_o be_v often_o see_v a_o good_a while_n after_o the_o gouty_a pain_n and_o then_o by_o good_a mean_n and_o some_o patience_n dispel_v qu._n it_o seem_v then_o that_o the_o pain_n which_o be_v the_o cause_n of_o this_o symptom_n cease_v the_o outward_a tumour_n do_v not_o vanish_v at_o the_o same_o time_n an._n no_o for_o very_o often_o the_o limb_n remain_v swell_v as_o before_o and_o it_o require_v some_o day_n

remedy_n itself_o as_o also_o by_o the_o pruriency_n and_o shiver_v which_o gouty_a person_n upon_o the_o motion_n of_o this_o cold_a damp_n do_v common_o feel_v especial_o in_o those_o part_n through_o which_o it_o take_v its_o course_n as_o also_o happen_v in_o epilepsy_n pleurisy_n colic_n and_o the_o like_a that_o come_v from_o cold_a damp_n qu._n but_o soft_a and_o fair_a your_o last_o proof_n take_v from_o shiver_a do_v not_o hold_v as_o beverwyck_n object_n for_o than_o shall_v the_o matter_n of_o hot_a fever_n be_v also_o cold_a which_o pass_v through_o part_n endow_v with_o the_o sense_n of_o feeling_n not_o only_a cause_n shiver_v but_o also_o clash_v of_o tooth_n ans_fw-fr this_o be_v not_o say_v from_o well-grounded_n knowledge_n since_o it_o have_v never_o yet_o that_o i_o know_v be_v satisfactory_o prove_v that_o hot_a fever_n as_o they_o be_v call_v must_v needs_o proc_v from_o a_o hot_a cause_n and_o upon_o a_o thorough_a disquisition_n it_o may_v perhaps_o be_v find_v that_o they_o have_v be_v produce_v from_o some_o cold_a matter_n or_o other_o which_o i_o think_v at_o least_o to_o be_v half_o prove_v because_o sometime_o a_o hot_a fever_n end_v in_o the_o gout_n as_o i_o have_v find_v not_o to_o go_v far_o in_o myself_o when_o i_o be_v in_o the_o 50_o the_o year_n of_o my_o age_n it_o sometime_o also_o come_v to_o pass_v that_o the_o gout_n determine_v in_o a_o hot_a fever_n as_o appear_v from_o what_o beverwyck_n say_v in_o his_o book_n of_o the_o gout_n p._n 110._o speak_v of_o the_o way_n through_o which_o the_o gouty_a matter_n take_v its_o course_n the_o damp_n say_v he_o turn_v back_o into_o the_o vein_n and_o ascend_v up_o again_o to_o the_o noble_a part_n mean_v the_o heart_n where_o it_o raise_v hot_a fever_n anguish_n and_o the_o like_a evil_n or_o shoot_v sudden_o into_o some_o other_o limb_n whereby_o the_o pain_n that_o be_v in_o the_o hand_n be_v soon_o after_o feel_v in_o the_o foot_n qu._n but_o be_v not_o that_o notable_a inflammation_n which_o be_v often_o see_v and_o feel_v in_o the_o gout_n sufficient_a proof_n that_o there_o be_v a_o sort_n of_o gout_n which_o come_v from_o heat_n ans_fw-fr this_o be_v a_o symptom_n or_o accident_n in_o the_o gout_n which_o be_v not_o cause_v by_o the_o next_o and_o always_o accompany_v cause_n of_o it_o but_o by_o the_o violent_a pain_n as_o i_o shall_v more_o clear_o make_v out_o when_o i_o come_v to_o speak_v of_o this_o symptom_n but_o it_o be_v a_o symptom_n not_o to_o pass_v that_o by_o in_o this_o place_n which_o have_v strange_o mislead_v those_o who_o have_v mistake_v it_o for_o a_o mark_n of_o the_o gout_n as_o sennertus_n and_o other_o do_v ackuowledg_n qu._n be_v this_o damp_n also_o ill-conditioned_n and_o malignant_a ans_fw-fr so_o it_o be_v judge_v by_o considerable_a and_o experience_a man_n as_o well_o as_o by_o myself_o and_o that_o from_o the_o intolerable_a pain_n and_o other_o accident_n so_o do_v that_o old_a master_n guido_n de_fw-fr culiaco_n and_o pareus_n in_o his_o seven_o book_n ch_n 2._o prove_v it_o by_o two_o example_n and_o our_o new_a medicine_n confirm_v the_o same_o beside_o the_o foetid_v damp_n of_o the_o gout_n do_v plain_o speak_v this_o malignity_n which_o be_v perceive_v both_o at_o the_o time_n of_o the_o act_n of_o burn_a and_o after_o it_o that_o be_v such_o that_o sometime_o both_o the_o patient_n and_o the_o person_n that_o administer_v the_o caustick_a and_o dress_v the_o part_n be_v ready_a to_o fall_v away_o and_o this_o be_v most_o of_o all_o find_v at_o the_o dress_n of_o the_o little_a wound_n when_o they_o begin_v to_o omit_v good_a store_n of_o moisture_n for_o as_o soon_o as_o you_o shall_v in_o a_o morning_n open_v the_o little_a plaster_n you_o will_v be_v so_o strike_v with_o a_o strange_a stink_a smell_n that_o it_o will_v almost_o cast_v you_o into_o a_o swoon_n it_o be_v very_o probable_a that_o this_o stuff_n be_v already_o malign_v before_o it_o be_v cast_v out_o from_o the_o heart_n into_o the_o limb_n yet_o remain_v for_o a_o while_n wedge_v in_o the_o limb_n from_o the_o evaporation_n obstruct_v its_o malignity_n be_v heighten_v hence_o it_o be_v not_o advisable_v to_o serve_v this_o burn_a or_o dress_v upon_o any_o one_o that_o be_v fast_v but_o it_o be_v best_a that_o both_o the_o patient_n and_o the_o agent_n shall_v first_o breakfast_v and_o take_v a_o cordial_a qu._n but_o be_v it_o possible_a for_o wind_n to_o occasion_n so_o much_o mischief_n ans_fw-fr very_o possible_a and_o then_o especial_o when_o they_o be_v more_o peccant_a by_o their_o quality_n than_o quantity_n so_o hypocrates_n in_o his_o golden_a tract_n of_o flatus_n do_v not_o without_o cause_n judge_v of_o wind_n that_o most_o of_o all_o the_o grievous_a and_o dangerous_a disease_n owe_v their_o original_n to_o they_o qu._n but_o can_v wind_n breed_v such_o viclent_a pain_n ans_fw-fr they_o can_v chief_o when_o the_o membrane_n the_o main_a instrument_n of_o the_o sense_n of_o feel_v be_v by_o they_o attack_v and_o distend_v chap._n v._n of_o the_o part_n affect_v and_o seat_n of_o the_o gouty_a matter_n qu._n which_o then_o in_o this_o painful_a disease_n be_v the_o part_n that_o be_v attack_v and_o offend_v by_o these_o wind_n ans_fw-fr principal_o if_o not_o only_o that_o sensible_a membrane_n call_v the_o periostium_fw-la that_o be_v that_o membrane_n which_o immediate_o cover_v the_o bone_n qu._n do_v you_o not_o think_v that_o the_o membranous_a ligament_n do_v also_o suffer_v here_o or_o rather_o the_o membrane_n of_o the_o ligament_n ans_fw-fr no_o but_o i_o agree_v herein_o with_o galen_n that_o they_o have_v no_o feel_n the_o which_o be_v also_o confirm_v by_o the_o learned_a barbette_v in_o his_o praxis_fw-la chap._n 5._o p._n 30._o qu._n what_o do_v you_o understand_v by_o the_o periostium_a ans_fw-fr that_o single_a membrane_n or_o film_n whereby_o the_o author_n of_o nature_n have_v outward_o invest_v and_o cover_v all_o the_o bone_n of_o our_o body_n and_o which_o be_v a_o close_a and_o firm_a substance_n extendible_a and_o very_o sensible_a qu._n do_v the_o gouty_a matter_n fall_v from_o without_o upon_o this_o sensible_a periostium_fw-la fret_v and_o bite_v it_o by_o its_o acrimony_n ans_fw-fr not_o so_o for_o than_o it_o can_v not_o cause_v so_o intolerable_a a_o pain_n or_o the_o right_a gout_n qu._n where_o then_o be_v we_o to_o look_v for_o the_o true_a seat_n of_o the_o gouty_a matter_n ans_fw-fr nowhere_a else_o but_o between_o the_o membrane_n and_o the_o bone_n qu._n wherein_o then_o consist_v the_o genuine_a essence_n of_o this_o disease_n ans_fw-fr in_o the_o violent_a distension_n or_o stretch_v of_o this_o sensible_a membrane_n by_o the_o wind_n whereby_o this_o membrane_n be_v force_v out_o of_o its_o due_a and_o natural_a form_n and_o situation_n excite_v so_o violent_a a_o pain_n qu._n whence_o do_v you_o infer_v that_o the_o gouty_a matter_n lie_v so_o deep_a and_o particular_o between_o the_o membrane_n and_o the_o bone_n itself_o ans_fw-fr not_o only_o from_o the_o distend_a pain_n which_o be_v to_o i_o proof_n sufficient_a but_o also_o from_o the_o contumaciousness_n of_o the_o gout_n which_o make_v hypocrates_n say_v in_o his_o 6_o book_n aph_n 49._o that_o the_o gouty_a fit_n do_v not_o cease_v before_o the_o forty_o day_n and_o true_o whereas_o all_o other_o windy_a tumour_n that_o be_v not_o lodge_v so_o deep_a be_v in_o a_o short_a time_n make_v to_o evaporte_n this_o windy_a swell_n of_o the_o gout_n lie_v so_o deep_a and_o lurk_v under_o so_o firm_a and_o close_o a_o membrane_n and_o beside_o in_o a_o place_n of_o little_a warmth_n and_o itself_o come_v from_o a_o cold_a cause_n can_v be_v easy_o bring_v to_o a_o quick_a evaporation_n but_o by_o such_o a_o kind_n of_o remedy_n as_o we_o be_v qu._n have_v not_o the_o old_a and_o new_a master_n mistake_v the_o part_n affect_v and_o the_o true_a seat_n of_o the_o gout_n ans_fw-fr certain_o they_o have_v for_o to_o speak_v of_o the_o part_n affect_v and_o the_o seat_n together_o i_o must_v first_o allege_v the_o opinion_n of_o galen_n as_o it_o be_v cite_v by_o beverwyck_n he_o affirm_v that_o the_o gouty_a moisture_n do_v flow_v into_o the_o hollow_a of_o the_o joint_n and_o there_o force_v asunder_o the_o bone_n whereby_o the_o ligament_n and_o membrane_n that_o fasten_v they_o together_o be_v so_o violent_o expanded_a that_o they_o cause_v that_o excessive_a pain_n qu._n have_v this_o sentiment_n of_o the_o great_a galen_n be_v general_o judge_v and_o receive_v to_o be_v conform_v to_o truth_n ans_fw-fr it_o have_v be_v reject_v by_o many_o as_o by_o beverwyck_n and_o other_o and_o by_o other_o maintain_v qu._n where_o do_v those_o that_o contradict_v galen_n find_v the_o part_n affect_v and_o the_o seat_n ans_fw-fr in_o the_o

ligament_n and_o membrane_n that_o tie_v the_o bone_n together_o be_v penetrate_v and_o ouze_v through_o by_o a_o sharp_a humour_n qu._n what_o have_v move_v those_o that_o be_v of_o the_o late_a opinion_n to_o reject_v galen_n doctrine_n ans_fw-fr see_v and_o read_v beverwyck_n and_o other_o qu._n but_o how_o do_v galen_n refute_v their_o opinion_n who_o say_v that_o the_o gouty_a matter_n ouze_v through_o the_o ligament_n and_o membrane_n ans_fw-fr thus_o that_o never_o a_o gouty_a person_n have_v be_v perceive_v to_o have_v convulsion_n or_o drawing_n of_o the_o limb_n which_o yet_o must_v needs_o happen_v if_o the_o warm_a humour_n do_v pass_v through_o the_o ligament_n and_o membrane_n qu._n but_o these_o allege_v to_o strengthen_v their_o opinion_n first_o that_o the_o pain_n as_o soon_o as_o the_o limb_n be_v but_o touch_v present_o increase_v second_o the_o debility_n and_o troublesome_a motion_n of_o the_o part_n last_o the_o laxity_n of_o the_o ligament_n which_o be_v ouze_v through_o by_o the_o humour_n do_v stretch_v and_o sometime_o cause_n dislocation_n be_v not_o these_o solid_a reason_n to_o persuade_v you_o and_o all_o other_o that_o they_o have_v hit_v right_a ans_fw-fr not_o at_o all_o for_o their_o proof_n be_v lame_a in_o all_o its_o part_n and_o not_o to_o repeat_v the_o irrefragable_a proof_n of_o galen_n against_o their_o opinion_n the_o pain_n do_v not_o increase_v when_o the_o limb_n be_v but_o touch_v and_o move_v because_o forsooth_o the_o gouty_a matter_n have_v ouze_v through_o the_o ligament_n and_o membrane_n no_o for_o not_o these_o but_o the_o periostium_fw-la be_v the_o part_n affect_v in_o this_o evil_a which_o be_v by_o the_o gouty_a damp_n already_o distend_v be_v upon_o the_o touch_n or_o least_o motion_n of_o the_o limb_n irritate_v a_o new_a and_o so_o cause_v new_a pain_n where_o i_o establish_v this_o for_o a_o certain_a truth_n that_o never_o the_o gouty_a matter_n but_o only_o the_o accidental_a affluxed_a humour_n ouze_v through_o the_o ligament_n so_o as_o to_o occasion_n stretch_v and_o dislocation_n which_o we_o intend_v more_o full_o to_o make_v out_o when_o we_o come_v to_o speak_v of_o this_o accident_n of_o dislocation_n qu._n but_o against_o galen_n proof_n the_o defender_n of_o this_o opinion_n allege_v that_o it_o be_v no_o strange_a thing_n that_o the_o acrimonious_a humour_n of_o the_o gout_n ouze_a through_o the_o ligament_n of_o the_o joint_n cause_v no_o draw_v in_o the_o limb_n because_o say_v they_o the_o nerve_n themselves_o be_v not_o offend_v but_o only_o the_o membrane_n and_o membranous_a ligament_n which_o do_v not_o cause_v the_o motion_n and_o that_o therefore_o although_o they_o be_v seize_v with_o great_a pain_n they_o cause_v no_o convulsion_n just_a as_o it_o be_v also_o find_v in_o the_o toothache_n pleurisy_n and_o colic_n ans_fw-fr this_o be_v a_o exception_n that_o conclude_v nothing_o forasmuch_o as_o the_o gouty_a matter_n provoke_v not_o the_o organ_n of_o motion_n but_o those_o of_o sense_n chap._n vi_o that_o the_o gout_n be_v a_o general_a disease_n of_o the_o limb_n receive_v its_o denomination_n from_o that_o limb_n which_o it_o seize_v on_o together_o with_o the_o place_n in_o which_o the_o gouty_a matter_n be_v breed_v qu._n be_v the_o gout_n a_o general_a disease_n as_o galen_n affirm_v attacking_z all_o the_o joint_n of_o the_o limb_n of_o the_o body_n ans_fw-fr it_o be_v so_o general_a that_o not_o one_o external_a part_n of_o any_o limb_n of_o the_o whole_a body_n be_v by_o its_o own_o nature_n exempt_a from_o it_o the_o reason_n be_v because_o that_o all_o part_n and_o limb_n be_v wrap_v about_o with_o this_o sensible_a membrane_n call_v periostium_fw-la the_o head_n neck_n jawbone_n breast_n back_o and_o the_o tooth_n themselves_o forasmuch_o as_o they_o be_v enclose_v in_o their_o grove_n or_o pit_n qu._n do_v this_o disease_n take_v different_a name_n according_a to_o the_o limb_n which_o it_o infest_v ans_fw-fr it_o do_v so_o hence_o it_o be_v call_v podagra_fw-la when_o it_o fall_v upon_o the_o foot_n gonagra_n when_o upon_o the_o knee_n chiragra_fw-la when_o upon_o the_o hand_n ischiatica_n when_o upon_o the_o hip_n and_o so_o the_o toothache_n when_o upon_o the_o tooth_n the_o pleurisy_n when_o upon_o the_o skin_n that_o clothes_n the_o rib_n etc._n etc._n all_o which_o i_o esteem_v to_o proceed_v from_o one_o and_o the_o same_o cause_n though_o many_o will_v think_v this_o strange_a qu._n what_o be_v the_o antecedent_n cause_n of_o the_o gout_n ans_fw-fr whatsoever_o breed_v these_o damp_n qu._n in_o what_o place_n grow_v this_o damp_n be_v the_o next_o cause_n of_o the_o gout_n ans_fw-fr the_o learned_a do_v as_o little_o agree_v in_o this_o as_o they_o do_v in_o the_o next_o cause_n itself_o and_o fernelius_n complain_v that_o no_o man_n have_v thorough_o search_v into_o this_o point_n and_o that_o through_o the_o want_n of_o the_o knowledge_n thereof_o the_o gout_n have_v be_v leave_v for_o incurable_a qu._n be_v this_o peccant_a matter_n breed_v only_o in_o the_o head_n except_v the_o skull_n as_o fernelius_n will_v have_v it_o or_o without_o the_o brain_n as_o other_o think_v or_o most_o of_o all_o in_o the_o viscera_n as_o the_o stomach_n spleen_n liver_n gall_n and_o the_o rest_n ans_fw-fr i_o give_v my_o voice_n for_o those_o that_o affirm_v the_o last_o viz._n that_o these_o gouty_a damp_n be_v most_o generate_v in_o the_o inner_a part_n yet_o not_o except_v the_o head_n qu._n but_o can_v you_o tell_v sir_n in_o what_o manner_n they_o be_v there_o produce_v ans_fw-fr doubtless_o they_o be_v through_o want_n of_o heat_n gather_v and_o lay_v up_o in_o some_o or_o other_o of_o the_o aforementioned_a part_n from_o corrupt_a humour_n and_o particular_o from_o corrupt_a blood_n chap._n vii_o how_o and_o through_o which_o way_n the_o gouty_a matter_n come_v to_o the_o limb_n qu._n since_o these_o morbid_v damp_n do_v cause_n such_o grievous_a pain_n in_o the_o external_a limb_n but_o be_v breed_v in_o the_o inner_a part_n by_o what_o mean_n and_o passage_n do_v they_o come_v to_o those_o limb_n an._n by_o mean_n of_o the_o circulation_n of_o the_o blood_n through_o the_o manifest_a way_n of_o vein_n and_o artery_n qu._n do_v not_o these_o damp_n ascend_v or_o descend_v direct_o into_o the_o limb_n without_o pass_v the_o heart_n an._n they_o must_v needs_o first_o pass_v into_o the_o heart_n qu._n by_o what_o way_n an._n through_o the_o vein_n which_o gather_v out_o of_o the_o inner_a part_n the_o generate_v damp_n carry_v they_o together_o with_o the_o not_o yet_o sufficient_o concoct_v blood_n into_o the_o heart_n qu._n but_o do_v not_o these_o malign_a damp_n offend_v that_o noble_a part_n see_v they_o cause_v such_o grievous_a pain_n in_o the_o limb_n ans_fw-fr certain_o they_o do_v and_o be_v the_o cause_n of_o fever_n beat_v of_o the_o heart_n and_o other_o distemper_n and_o frequent_o cause_n death_n when_o the_o heart_n want_v strength_n and_o vigour_n to_o expel_v they_o chap._n viii_o of_o the_o expel_v part._n qu._n be_v the_o heart_n than_o the_o only_a strong_a expelling_a part_n which_o drive_v those_o damp_n into_o the_o limb_n an._n it_o be_v as_o be_v evince_v by_o the_o strong_a motion_n and_o beat_n of_o the_o artery_n in_o the_o gout_n whereby_o the_o heart_n labour_v to_o deliver_v itself_o from_o such_o a_o pernicious_a damp_n and_o to_o discharge_v and_o purify_v the_o nourish_a blood_n of_o the_o same_o qu._n through_o what_o way_n do_v the_o heart_n drive_v out_o these_o damp_n into_o the_o limb_n an._n through_o the_o artery_n qu._n whence_o be_v it_o that_o the_o gout_n for_o the_o most_o part_n manifest_v itself_o in_o the_o extremity_n of_o the_o limb_n of_o the_o body_n as_o for_o example_n in_o the_o great_a toe_n of_o the_o left_a foot_n an._n because_o that_o the_o heart_n undertake_v the_o expulsion_n drive_v this_o offensive_a matter_n as_o far_o as_o it_o can_v qu._n may_v one_o from_o the_o gout_n judge_v of_o the_o vigour_n and_o debility_n of_o the_o heart_n an._n you_o may_v probable_o do_v so_o from_o the_o suffer_a part_n for_o if_o that_o be_v far_o from_o the_o heart_n than_o the_o heart_n be_v strong_a if_o near_o it_o then_o it_o be_v less_o vigorous_a and_o unable_a to_o send_v that_o noxious_a matter_n far_o away_o qu._n but_o when_o the_o heart_n through_o the_o artery_n do_v expel_v into_o the_o limb_n together_o with_o the_o nourish_a blood_n these_o damp_n must_v those_o limb_n receive_v they_o an._n they_o must_v receive_v they_o as_o well_o as_o the_o nutritive_a blood_n which_o accompany_v it_o the_o heart_n expel_v they_o chief_o by_o the_o force_n of_o the_o artery_n not_o rest_v till_o they_o be_v thrust_v out_o qu._n but_o why_o do_v not_o the_o part_n aggrieve_v expel_v those_o damp_n and_o send_v they_o further_o away_o an._n