contract_v it_o be_v round_o even_o polite_a and_o true_o represent_v thing_n 11._o deadness_n of_o the_o eye_n to_o the_o view_n be_v as_o have_v be_v show_v from_o the_o laxity_n of_o the_o cornea_n which_o make_v it_o flag_n lie_v loose_a look_v dull_o and_o not_o due_o reflect_v a_o smart_n and_o brisk_a speck_n of_o light_n as_o it_o do_v when_o tense_n round_o and_o polite_a by_o its_o contraction_n on_o the_o contain_v humour_n which_o then_o due_o fill_v it_o 12._o falter_v of_o the_o tongue_n be_v from_o the_o same_o relaxation_n as_o in_o drunken_a person_n 13._o a_o sopor_fw-la be_v from_o the_o same_o relaxation_n over_o all_o the_o sensile_a part_n of_o the_o body_n by_o which_o mean_v sense_n and_o motion_n be_v diminish_v or_o lose_v by_o the_o expansion_n of_o the_o animal_n spirit_n which_o as_o have_v be_v say_v be_v not_o due_o compress_v become_v unfit_a for_o both_o at_o the_o same_o time_n 14._o a_o slow_a and_o wide_a pulse_n be_v from_o the_o same_o cause_n because_o the_o say_a relaxation_n permit_v the_o artery_n to_o widen_v and_o the_o animal_n spirit_n to_o expand_v and_o consequent_o render_v the_o motion_n of_o the_o heart_n slow_a which_o be_v the_o cause_n of_o the_o pulse_n 15._o a_o high_a colour_n or_o efflorescence_n of_o the_o skin_n have_v be_v explain_v 16._o looseness_n of_o the_o jaw_n and_o lip_n be_v from_o the_o same_o relaxation_n as_o be_v show_v and_o so_o be_v 17._o intumescence_n of_o the_o lip_n as_o have_v be_v show_v 18._o difficulty_n of_o breathe_v may_v be_v from_o two_o different_a cause_n either_o by_o the_o relaxation_n weaken_v the_o requisite_a motion_n for_o want_n of_o compressure_n of_o the_o animal_n spirit_n and_o by_o the_o flaccity_n of_o the_o part_n themselves_o or_o by_o a_o great_a grievance_n at_o stomach_n upon_o the_o account_n of_o the_o rosin_n stick_v to_o it_o and_o cause_v a_o convulsion_n of_o those_o part_n both_o which_o may_v happen_v 19_o fury_n and_o madness_n may_v also_o happen_v either_o by_o the_o exalt_a pleasure_n of_o its_o titillation_n as_o in_o drunkard_n who_o therefore_o scarce_o know_v what_o they_o do_v the_o mind_n be_v as_o be_v say_v alienate_v or_o it_o may_v happen_v as_o i_o have_v often_o know_v a_o kind_n of_o madness_n to_o be_v produce_v by_o a_o great_a grievance_n at_o stomach_n which_o may_v well_o be_v from_o the_o rosin_n grieve_v and_o teaze_v the_o nice_o sensile_a stomach_n they_o may_v be_v easy_o distinguish_v one_o viz._n that_o from_o the_o rosin_n at_o stomach_n be_v with_o great_a distress_n anxiety_n convulsion_n etc._n etc._n and_o the_o other_o without_o any_o 20._o venereal_a fury_n proceed_v from_o the_o high_a titillation_n of_o the_o venereal_a membrane_n by_o the_o volatile_a salt_n of_o so_o much_o opium_n as_o if_o cantharides_n bee_n &c_n &c_n be_v take_v internal_o but_o that_o these_o can_v so_o agreeable_o titillate_v those_o part_n as_o opium_n do_v who_o volatile_a particle_n be_v render_v more_o please_a by_o oily_a one_o and_o therefore_o much_o of_o the_o nature_n of_o semen_n virile_a 21._o priapism_n be_v cause_v by_o the_o same_o continual_a titillation_n 22._o violent_a itch_n of_o the_o skin_n be_v cause_v by_o the_o same_o tickle_a volatile_a particle_n in_o great_a abundance_n proportionable_a to_o the_o excessive_a do_v 23._o nauseas_fw-la be_v cause_v by_o the_o rosin_n stick_v at_o and_o solicit_v the_o stomach_n to_o vomit_v 24._o swimmings_n in_o the_o head_n be_v by_o conseâ—it_n because_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o be_v observe_v in_o many_o case_n from_o a_o grieve_a stomach_n upon_o a_o tendency_n to_o vomit_v as_o when_o it_o be_v overload_v with_o wine_n or_o indigestible_a victual_n or_o when_o person_n be_v sea_n or_o coach-sick_a etc._n etc._n for_o it_o be_v not_o in_o these_o last_o case_n because_o the_o brain_n be_v offend_v as_o people_n imagine_v that_o they_o be_v sick_a or_o vomit_n but_o the_o swim_v in_o the_o head_n and_o offence_n of_o the_o brain_n happen_v because_o the_o stomach_n be_v offend_v by_o the_o motion_n of_o the_o coach_n or_o ship_n by_o reason_n of_o its_o most_o exquisite_a sensation_n which_o the_o effluvias_fw-la of_o a_o cat_n pestiferous_a particle_n and_o commotion_n cause_v by_o mear_v passion_n can_v and_o do_v offend_v as_o be_v say_v so_o as_o to_o cause_v vomit_n anxiety_n etc._n etc._n much_o more_o than_o may_v the_o motion_n of_o a_o ship_n or_o coach_n do_v it_o i_o shall_v not_o here_o enter_v into_o controversy_n with_o those_o that_o assert_v that_o it_o be_v the_o head_n be_v first_o offend_v in_o a_o coach_n or_o ship_n it_o be_v sufficient_a for_o my_o purpose_n that_o grievance_n at_o stomach_n do_v common_o cause_n swimmings_n in_o the_o head_n for_o take_v off_o those_o grievance_n cure_v they_o as_o eat_v when_o it_o be_v from_o the_o grievance_n of_o hunger_n or_o wind_n at_o stomach_n and_o discharge_v the_o stomach_n of_o a_o great_a load_n of_o wine_n ale_z or_o indigestible_a matter_n when_o such_o thing_n cause_v it_o do_v cure_v such_o swimming_n in_o the_o head_n the_o way_n how_o grievance_n at_o stomach_n do_v cause_n those_o swimming_n be_v by_o cause_v a_o contraction_n as_o all_o grievance_n do_v but_o especial_o those_o at_o stomach_n of_o the_o membrane_n of_o the_o brain_n as_o it_o do_v of_o all_o other_o but_o main_o of_o these_o because_o very_o sensile_a by_o which_o mean_v the_o animal_n spirit_n be_v compress_v grow_v more_o irrequiete_a and_o skip_a up_o and_o down_o and_o the_o compression_n not_o be_v continual_o alike_o in_o general_n or_o the_o artery_n afford_v a_o uneven_a and_o forcible_a supply_n of_o they_o or_o fume_n from_o the_o blood_n by_o the_o compression_n nor_o affect_v all_o part_n of_o the_o brain_n with_o equal_a force_n because_o the_o pleasure_n endeavour_n to_o relax_v etc._n etc._n there_o must_v thence_o arise_v eddy_n vortices_fw-la or_o whirl_v thereof_o which_o cause_n swimmings_n vertigo_n &c._n &c._n according_a as_o they_o happen_v to_o be_v move_v that_o they_o happen_v from_o such_o contraction_n be_v manifest_a 1._o because_o the_o grievance_n at_o stomach_n can_v add_v nothing_o else_o to_o the_o brain_n or_o its_o membrane_n 2._o because_o they_o be_v take_v off_o by_o please_v the_o stomach_n and_o consequent_o by_o relaxation_n as_o by_o a_o glass_n of_o wine_n victual_n a_o opiate_n that_o be_v not_o resinous_a etc._n etc._n it_o be_v here_o well_o worth_a your_o notice_n that_o all_o consent_n of_o part_n a_o thing_n much_o admire_v be_v only_o by_o contraction_n or_o relaxation_n which_o sudden_o affect_v the_o whole_a systeme_n of_o the_o nerve_n and_o membrane_n 25._o vertigo_n be_v from_o the_o same_o cause_n 26._o vomit_n be_v cause_v as_o be_v say_v by_o the_o great_a grievance_n of_o the_o acrimonious_a rosin_n stick_v to_o the_o coat_n of_o the_o stomach_n 27._o hiccongh_n be_v from_o the_o same_o cause_n which_o happen_v upon_o the_o decay_n of_o power_n vigorous_o to_o vomit_v dwindle_v into_o those_o fruitless_a convulsive_a subsultory_n jerâ—_n or_o half_a endeavour_n 28._o distress_n and_o anxiety_n must_v necessary_o attend_v such_o a_o grievous_a sensation_n and_o desection_n of_o nature_n endeavour_v as_o be_v overbear_v and_o disable_v to_o work_v for_o itself_o 29._o a_o turbulent_a pulse_n must_v be_v a_o effect_n of_o the_o forego_n tumult_n 30._o convulsion_n happen_v as_o be_v show_v by_o the_o enormous_a compression_n of_o the_o animal_n spirit_n by_o reason_n of_o the_o violent_a contraction_n upon_o the_o great_a grievance_n by_o the_o rosin_n at_o stomach_n which_o cause_v they_o to_o skip_v and_o fling_v up_o and_o down_o very_o forcible_o under_o the_o squeeze_v of_o the_o compression_n and_o possible_o skirmish_v under_o the_o vicissitude_n of_o it_o and_o relaxation_n 31._o faint_n and_o leipothymy_n be_v cause_v as_o have_v be_v explain_v by_o the_o sensitive_a soul_n be_v overtired_n by_o the_o fatigue_n of_o defensive_a contraction_n and_o yield_v himself_o to_o rest_n from_o all_o contraction_n as_o the_o last_o relief_n etc._n etc._n whereupon_o sense_n and_o motion_n do_v fail_v for_o want_v of_o compression_n to_o render_v the_o spirit_n springy_a active_a and_o fit_a for_o the_o purpose_n 32._o cold_a breath_n be_v but_o a_o necessary_a consequence_n of_o the_o loss_n of_o motion_n and_o therefore_o of_o heat_n by_o such_o leipothymy_n and_o faint_n 33._o death_n be_v cause_v two_o manner_n of_o way_n that_o be_v either_o by_o a_o utter_a expense_n of_o spirit_n and_o thereupon_o a_o dereliction_n or_o extinction_n of_o the_o sensitive_a soul_n by_o reason_n of_o those_o distress_n and_o fatigue_n upon_o the_o account_n of_o the_o invincible_a rosin_n or_o by_o too_o much_o relaxation_n disable_n all_o the_o motion_n of_o the_o body_n as_o in_o such_o as_o die_v be_v dead_a drink_v
13._o some_o of_o the_o ancient_n apply_v it_o to_o the_o perineum_n kidney_n region_n of_o the_o pubis_fw-la etc._n etc._n to_o chill_a venus_n by_o the_o cold_a quality_n they_o attribute_v to_o it_o which_o be_v all_o stuff_n ground_v upon_o that_o most_o absurd_a hypothesis_n 14._o they_o also_o attribute_v its_o psilothrick_n quality_n to_o cold_a than_o which_o nothing_o do_v more_o fasten_v and_o cause_v the_o hair_n to_o grow_v as_o you_o see_v in_o wintertime_n when_o all_o fur_n be_v long_o and_o fasten_v better_a to_o the_o skin_n into_o what_o foolery_n a_o false_a opinion_n will_v lead_v people_n 15._o it_o have_v be_v use_v by_o hieron_n mercurialis_n in_o ulcer_n of_o the_o womb_n with_o success_n and_o without_o danger_n as_o he_o say_v l._n 4._o de_fw-fr morb._n mul._n c._n 7._o p._n 281._o 16._o it_o have_v kill_v people_n in_o clyster_n by_o sâ—icking_v to_o the_o intestinum_fw-la rectum_fw-la which_o be_v doubtless_o by_o reason_n of_o its_o rosin_n for_o it_o have_v nothing_o in_o it_o beside_o the_o rosin_n that_o can_v stick_v to_o do_v any_o manner_n of_o harm_n which_o be_v a_o most_o demonstrative_a reason_n of_o the_o perniciousness_n of_o its_o rosin_n for_o if_o it_o can_v â—ill_v there_o much_o more_o where_o there_o be_v such_o exquisite_a sensation_n as_o be_v at_o stomach_n however_o it_o be_v know_v by_o experience_n that_o venice_n treacle_n and_o diascordium_n be_v because_o of_o the_o dissemination_n of_o the_o opium_n and_o smallness_n of_o the_o quantity_n safe_a in_o clyster_n and_o very_o useful_a in_o dysentery_n and_o diarrhaea_n as_o our_o panacea_fw-la must_v be_v that_o have_v no_o rosin_n in_o it_o and_o dissolvable_a in_o water_n or_o any_o humour_n of_o the_o body_n 17._o it_o may_v be_v use_v in_o suppository_n when_o the_o rosin_n be_v separate_v from_o it_o but_o i_o will_v not_o advise_v the_o use_n of_o above_o 4_o grain_n in_o this_o case_n or_o if_o 8_o or_o ten_o be_v use_v the_o suppository_n shall_v not_o remain_v long_o in_o the_o body_n this_o i_o say_v for_o caution_n sake_n 18._o it_o have_v be_v use_v reduce_v to_o a_o oointment_n or_o balsam_n with_o oil_n of_o rose_n etc._n etc._n to_o the_o sol_n of_o the_o â—eet_a to_o cause_v sleep_n with_o good_a success_n 〈◊〉_d polidamus_n l._n de_fw-fr doloribus_fw-la capitis_fw-la p._n 78._o 19_o d._n francisc._n hildesheâ—m_n assert_n that_o it_o take_v away_o pain_n in_o cautery_n â—ut_fw-la say_v it_o be_v apt_a to_o cause_n grangrens_n 20._o crollius_n in_o his_o basil._n chym._n p._n 235._o say_n that_o 2_o pill_n of_o opium_n each_o contain_n 8_o grain_n be_v put_v up_o into_o the_o nostril_n stop_v a_o desperate_a haemorrhage_n at_o nose_n but_o i_o shall_v hardly_o â—rust_v it_o in_o this_o case_n possible_o the_o blood_n may_v stop_v by_o some_o other_o cause_n a_o small_a deliquium_fw-la not_o observe_v or_o the_o like_a for_o deliquium_n still_o all_o motion_n by_o a_o sudden_a relaxation_n which_o as_o have_v be_v say_v suspend_v all_o humour_n and_o weaken_v the_o motion_n of_o the_o heart_n if_o it_o do_v not_o sometime_o quite_o take_v it_o off_o for_o the_o time_n second_o as_o a_o alterative_a emplostick_n &c_n &c_n it_o as_o be_v show_v incides_fw-la resolve_n discuss_n molleâ—ies_n maturate_n suppurate_n and_o be_v psilothrick_n and_o titillative_a therefore_o be_v of_o use_n 1._o in_o phlegmatic_a and_o oedematous_a tumor_n 2_o in_o windy_a tumor_n pain_n stitch_n etc._n etc._n 3._o to_o ripen_v boil_n bubo_n abscess_n and_o the_o like_a 4._o in_o all_o hard_a tumor_n of_o the_o spleen_n breast_n cancer_n tophousness_n etc._n etc._n in_o which_o case_n it_o be_v as_o other_o opiate_n be_v of_o excellent_a use_n by_o their_o powerful_a resolve_v and_o relax_v faculty_n 5._o to_o cause_v nourishment_n of_o part_n increase_v of_o milk_n etc._n etc._n by_o relaxation_n as_o sleep_v puberty_n pleasure_n etc._n etc._n do_v as_o have_v be_v show_v 6._o to_o cause_v the_o shed_n of_o hair_n by_o resolution_n of_o the_o part_n as_o by_o a_o caustick_a vesicatory_a etc._n etc._n with_o which_o it_o agree_v in_o its_o exulcerate_v faculty_n when_o it_o be_v very_o strong_a as_o the_o true_a maslach_n or_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d which_o we_o have_v not_o 7._o to_o excite_v to_o venery_n by_o its_o titillate_v volatile_a salâ—_n if_o apply_v to_o the_o perinaeum_n you_o bless_a mind_n who_o in_o a_o instant_n know_v what_o in_o five_o thousand_o year_n none_o here_o below_o can_v learn_v how_o mean_v be_v we_o how_o great_a be_v you_o o_o for_o your_o happy_a state_n while_o dull_a mankind_n oft_o see_v and_o fâ—el_v the_o thing_n they_o can_v find_v who_o do_v not_o see_v the_o blood_n move_v to_o and_o fro_o yet_o can_v none_o be_v circulation_n know_v till_o god_n enlighten_v harvey_n then_o do_v he_o perceive_v what_o other_o see_v can_v not_o see_v so_o till_o god_n be_v to_o my_o inquiry_n kind_a million_o seek_v and_o feel_v what_o they_o never_o can_v find_v what_o be_v vain_a man_n without_o the_o all_o know_a mind_n to_o who_o all_o glory_n be_v all_o thanks_o and_o praise_v as_o be_v be_v now_o and_o fit_a to_o be_v always_o amen_n amen_n amen_n finis_fw-la
a_o very_o long_o and_o lavish_a use_n thereof_o the_o inconvenience_n of_o leave_v off_o the_o use_n of_o opium_n do_v bear_v a_o certain_a proportion_n to_o the_o time_n and_o quantity_n that_o it_o have_v be_v use_v in_o 1._o note_v that_o the_o turk_n do_v drink_v some_o water_n always_o after_o the_o take_n of_o opium_n as_o be_v the_o best_a menstruum_fw-la to_o dissolve_v it_o 2._o note_v that_o it_o be_v usual_a with_o they_o to_o take_v a_o drachm_n in_o the_o morning_n and_o so_o much_o in_o the_o afternoon_n and_o so_o may_v we_o as_o well_o as_o they_o if_o use_v to_o it_o and_o it_o be_v a_o very_a silly_a say_n that_o you_o will_v find_v in_o author_n that_o they_o be_v better_a able_a to_o bear_v it_o because_o of_o the_o climate_n etc._n etc._n whereas_o the_o more_o northern_a person_n be_v better_a able_a to_o take_v it_o than_o the_o southern_a as_o will_v hereafter_o appear_v most_o plain_o i_o be_o tell_v of_o one_o near_o banbury_n that_o take_v two_o ounce_n a_o day_n 3._o note_v that_o among_o the_o effect_n of_o opium_n may_v be_v observe_v many_o seem_a contradiction_n yet_o be_v there_o nothing_o more_o certain_a than_o the_o several_a different_a matter_n of_o fact_n which_o no_o doubt_n have_v be_v a_o great_a cause_n to_o puzzle_v the_o world_n about_o it_o and_o to_o run_v man_n into_o strange_a absurdity_n concern_v its_o operation_n and_o all_o to_o deviate_v so_o far_o from_o the_o truth_n that_o nothing_o in_o nature_n can_v be_v far_o unless_o you_o will_v say_v that_o heat_n cool_v or_o what_o please_v the_o sensitive_a soul_n be_v at_o the_o same_o time_n abhor_v by_o it_o now_o because_o these_o seem_a contradiction_n in_o the_o effect_n of_o opium_n be_v the_o great_a rub_n to_o be_v meet_v with_o and_o that_o the_o reader_n may_v take_v the_o better_a estimate_n of_o the_o undertake_n and_o my_o explication_n of_o its_o effect_n when_o i_o come_v to_o it_o i_o shall_v not_o fear_v to_o enumerate_v they_o distinct_o though_o they_o will_v make_v the_o strange_a catalogue_n of_o riddle_n that_o ever_o be_v see_v trust_v in_o he_o that_o create_v this_o wonderful_a medicament_n that_o he_o will_v enable_v i_o to_o explain_v all_o its_o effect_n the_o seem_a contradiction_n in_o the_o effect_n of_o opium_n 1._o it_o cause_v sleep_v and_o watch_v 2._o it_o cause_n and_o prevent_v sweat_n 3._o it_o relax_n and_o stop_v looseness_n 4._o it_o stop_v flux_n and_o cause_n that_o of_o sweat_n etc._n etc._n 5._o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v by_o that_o sense_n to_o venery_n 6._o it_o cause_v stupidity_n and_o promptitude_n in_o business_n cloudiness_n and_o serenity_n of_o mind_n 7._o it_o excite_v the_o spirit_n and_o quiet_v they_o 8._o it_o be_v very_o hot_a yet_o cool_v in_o fever_n 9_o it_o be_v hot_a and_o bitter_a yet_o lessen_v appetite_n even_o in_o cold_a stomach_n 10._o it_o stop_v and_o promote_v urine_n 11._o it_o relax_n and_o weaken_v yet_o enable_v we_o to_o undergo_v labour_n journey_n etc._n etc._n 12._o it_o cause_n and_o prevent_v abortion_n 13._o it_o stop_v vomit_v above_o all_o thing_n yet_o cause_n most_o violent_a tedious_a and_o dangerous_a vomit_n 14._o it_o stop_v purge_v in_o a_o most_o eminent_a manner_n yet_o sometime_o cause_v it_o 15._o it_o be_v very_o acrimonious_a yet_o as_o all_o say_v obtund_v acrimony_n however_o it_o allay_v pain_n proceed_v from_o acrimony_n 16._o it_o cause_v a_o furious_a madness_n yet_o compose_v the_o spirit_n above_o all_o thing_n 17._o it_o cause_v 〈◊〉_d yet_o sometime_o cure_v they_o as_o willis_n say_v 18._o it_o cause_v palsy_n yet_o have_v i_o know_v it_o to_o cure_v a_o palsy_n 19_o it_o cause_v dryness_n in_o the_o mouth_n yet_o take_v off_o thirst_n in_o fever_n 20._o it_o cure_v and_o cause_v a_o hiccough_n 21._o it_o stanche_n blood_n yet_o cause_v the_o blood_n to_o come_v outward_a as_o appear_v by_o the_o efflorescence_n or_o redness_n of_o the_o skin_n that_o it_o cause_n yet_o move_v the_o menses_fw-la and_o lochia_n 22._o we_o have_v many_o instance_n of_o it_o promote_a and_o hinder_v critical_a motion_n 23._o it_o raise_v very_o weak_a people_n when_o nothing_o beside_o will_v do_v it_o yet_o it_o kill_v other_o weak_a people_n 24._o it_o cause_n and_o cure_n convulsion_n 25._o it_o cause_v relaxation_n and_o contraction_n of_o the_o same_o part_n 26._o it_o relax_n yet_o cause_v rigidity_n tension_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n thus_o have_v i_o fair_o and_o faithful_o lay_v the_o whole_a onus_fw-la of_o the_o operation_n effect_n and_o contradictory_n phenomena_n of_o opium_n upon_o my_o shoulder_n however_o i_o come_v off_o and_o clear_v myself_o of_o the_o intricacy_n maze_n and_o cross_a effect_n thereof_o by_o explain_v they_o which_o none_o upon_o the_o view_n thereof_o will_v think_v possible_a and_o none_o before_o i_o dare_v as_o much_o as_o enumerate_v for_o that_o end_n chap._n vii_o the_o author_n contrive_v a_o compendious_a way_n of_o examine_v all_o opinion_n concern_v the_o operation_n of_o opium_n have_v without_o any_o sly_a or_o sordid_a evasion_n or_o considerable_a omission_n which_o have_v be_v the_o perfidious_a course_n of_o author_n in_o this_o case_n full_o and_o true_o enumerate_v the_o sensible_a and_o certain_a effect_n of_o opium_n in_o humane_a body_n and_o thereby_o empanneled_a a_o just_a jury_n for_o the_o trial_n of_o hypothesise_n which_o must_v be_v judge_v by_o the_o effect_n or_o phenomena_n of_o opium_n i_o will_v now_o proceed_v to_o their_o examination_n but_o because_o it_o will_v be_v endless_a to_o take_v every_o one_o particular_o into_o consideration_n i_o will_v use_v their_o stratagem_n who_o blow_v up_o foundation_n to_o save_v the_o tedious_a peck_v at_o all_o the_o part_n of_o the_o superstructure_n which_o in_o this_o case_n will_v require_v a_o age_n and_o take_v up_o all_o my_o time_n in_o demolish_n they_o which_o may_v be_v better_o employ_v in_o erect_v something_o that_o may_v be_v useful_a i_o have_v consider_v and_o find_v that_o the_o foundation_n in_o which_o all_o author_n both_o ancient_a and_o modern_a agree_v and_o whereupon_o they_o have_v hitherto_o endeavour_v to_o build_v look_v upon_o it_o as_o firm_a and_o warrantable_a in_o all_o age_n be_v this_o viz._n that_o opium_n operate_v by_o diminish_v or_o disable_n the_o spirit_n mean_v the_o animal_n spirit_n the_o ancient_n affirm_v that_o it_o do_v so_o by_o a_o extreme_a cold_a quality_n etc._n etc._n and_o the_o modern_n who_o observe_v it_o to_o act_n while_o it_o be_v at_o stomach_n by_o affect_v the_o brain_n nerve_n animal_n spirit_n etc._n etc._n and_o conclude_v no_o action_n be_v perform_v without_o contact_n infer_v and_o agree_v because_o no_o visible_a passage_n can_v be_v find_v from_o the_o stomach_n to_o the_o head_n that_o it_o must_v of_o absolute_a necessity_n act_v by_o fume_n vapour_n auras_fw-la or_o effluvium_n send_v up_o out_o of_o the_o stomach_n to_o the_o brain_n nerve_n etc._n etc._n so_o that_o all_o the_o remain_a question_n among_o the_o modern_n be_v which_o way_n those_o fume_n or_o vapour_n do_v the_o feat_n all_o allow_v the_o fume_n do_v it_o one_o say_v that_o they_o stuff_v the_o pore_n of_o the_o brain_n and_o so_o hinder_v the_o generation_n of_o animal_n spirit_n a_o second_o that_o they_o constringed_a and_o close_v the_o pore_n together_o thereby_o hinder_v the_o say_a generation_n a_o three_o that_o they_o fix_v and_o coagulate_v the_o animal_n spirit_n as_o wedelius_n and_o other_o a_o four_o that_o they_o cloud_v the_o animal_n spirit_n a_o five_o that_o they_o act_v as_o a_o poison_n as_o willis_n and_o many_o other_o a_o six_o that_o they_o clog_v the_o animal_n spirit_n by_o adhere_v to_o they_o etc._n etc._n not_o know_v nor_o i_o think_v care_v what_o they_o say_v so_o they_o humour_a their_o own_o imagination_n and_o hypothesise_n though_o utter_o incapable_a of_o solve_v the_o effect_n of_o opium_n especial_o be_v most_o constant_a proper_a and_o genuine_a effect_n for_o how_o can_v a_o cold_a quality_n which_o opium_n never_o have_v cause_v a_o gay_a and_o brisk_a humour_n bravery_n magnanimity_n euphory_n in_o labour_n promptitude_n to_o venus_n etc._n etc._n and_o how_o can_v cloud_n of_o vapour_n hinder_v the_o generation_n of_o animal_n spirit_n by_o stuff_v or_o constr_v the_o pore_n of_o the_o brain_n poison_v fix_v coagulate_v clog_a or_o cloud_v the_o animal_n spirit_n cause_v a_o fine_a ovation_n thereof_o a_o gay_a brave_a courageous_a and_o magnanimous_a disposition_n euphory_n promptitude_n to_o venery_n serenity_n expediteness_n in_o management_n etc._n etc._n which_o be_v as_o have_v be_v say_v the_o constant_a and_o proper_a effect_n of_o opium_n nor_o indeed_o be_v any_o of_o those_o author_n so_o foolhardy_a as_o to_o attempt_v it_o
by_o squeeze_v in_o some_o case_n and_o stop_v it_o by_o shut_v the_o pore_n in_o other_o case_n 10._o it_o be_v by_o it_o that_o contraction_n that_o fear_v cold_a etc._n etc._n close_v the_o pore_n and_o repel_v the_o blood_n staunch_a bleed_a so_o happen_v also_o a_o great_a contraction_n of_o the_o pupil_n of_o the_o eye_n by_o the_o same_o cause_n 11._o it_o be_v the_o violence_n of_o this_o contraction_n upon_o fear_n terror_n pain_n cold_a etc._n etc._n close_v the_o small_a vessel_n of_o the_o animal_n spirit_n and_o thereby_o repel_v they_o cause_v the_o shiver_a in_o those_o case_n by_o the_o renitency_n of_o the_o elastic_a animal_n spirit_n spring_v back_o again_o toties_fw-la quoties_fw-la have_v gain_v more_o elastic_a force_n by_o the_o very_a compression_n itself_o which_o that_o contraction_n cause_n so_o that_o by_o reason_n of_o the_o dubious_a velitation_n or_o skirmish_v between_o the_o repel_v contraction_n and_o the_o spring_a spirit_n happen_v a_o tremulous_a motion_n as_o of_o quaver_v spring_n which_o shiver_a in_o ague-fits_a do_v former_o lead_v i_o to_o the_o situation_n of_o the_o cause_n of_o ague_n when_o i_o write_v my_o book_n de_fw-fr febribus_fw-la intermittentibus_fw-la in_o the_o angustiae_fw-la at_o the_o end_n of_o the_o vessel_n which_o terminate_v in_o the_o membrane_n the_o grievous_a sensation_n of_o which_o cause_v all_o the_o shiver_a that_o happen_v in_o any_o case_n to_o animal_n 12._o by_o the_o same_o contraction_n when_o very_o violent_a and_o of_o the_o whole_a body_n cold_a sweat_v happen_v in_o pain_n fear_v terror_n etc._n etc._n while_o it_o violent_o squeeze_v out_o the_o outmost_a and_o therefore_o cold_a moisture_n of_o our_o body_n as_o laundress_n do_v water_n out_o of_o wet_a linen_n by_o contortion_n thus_o if_o you_o dip_v one_o half_a of_o a_o wet_a cold_a sheet_n in_o hot_a water_n wrap_v the_o hot_a side_n within_o the_o cold_a or_o let_v a_o warm_a sheet_n that_o be_v contort_a cool_a on_o the_o outside_n of_o it_o and_o then_o wring_v it_o as_o woman_n do_v linen_n the_o water_n that_o first_o exudate_n will_v be_v cold_a for_o in_o this_o case_n the_o close_n of_o the_o pore_n avail_v nothing_o to_o hinder_v it_o as_o long_o as_o the_o express_a force_n master_n it_o more_o especial_o in_o animal_n body_n wherein_o the_o part_n be_v so_o contrive_v that_o humour_n design_v for_o exoretion_n can_v well_o return_v and_o therefore_o must_v upon_o contraction_n run_v out_o hence_o it_o be_v that_o alum_n or_o vitriol_n which_o be_v very_o astringent_a and_o therefore_o close_a the_o pore_n will_v notwithstanding_o cause_v the_o mouth_n or_o nose_n to_o run_v very_o plentiful_o with_o moisture_n by_o contract_v all_o the_o membrane_n about_o the_o mouth_n or_o nose_n and_o thereby_o squeeze_v out_o the_o moisture_n design_v to_o be_v excern_v which_o can_v return_v because_o the_o part_n be_v contrive_v against_o the_o return_n or_o readmittance_n thereof_o whereas_o alum_n or_o vitriol_n will_v staunch_v or_o stop_v blood_n by_o the_o same_o contraction_n because_o it_o may_v return_v as_o not_o be_v design_v to_o be_v excern_v either_o into_o the_o artery_n and_o so_o pass_v by_o other_o branch_n thereof_o or_o which_o be_v more_o ready_a and_o natural_a keep_v its_o course_n into_o the_o vein_n so_o the_o two_o riddle_n that_o i_o have_v know_v some_o proud_a physician_n amaze_v at_o though_o but_o trifle_n of_o alum_n and_o vitriol_n cause_v the_o spital_n etc._n etc._n to_o come_v out_o instead_o of_o stop_v it_o by_o their_o astringency_n and_o their_o stop_a blood_n at_o nose_n at_o the_o same_o time_n they_o cause_v the_o snot_n or_o other_o humour_n to_o run_v out_o be_v unfold_v 13._o it_o be_v by_o this_o mighty_a contraction_n grow_v to_o a_o enormous_a degree_n that_o the_o animal_n spirit_n be_v violent_o compress_v grow_v exceed_o irrequiete_a as_o upon_o convulsion_n in_o great_a pain_n or_o very_o grievous_a sensation_n at_o stomach_n etc._n etc._n while_o the_o sensitive_a soul_n compress_v they_o with_o mighty_a force_n and_o somewhat_o disorderly_a and_o uneven_o because_o of_o the_o confusion_n and_o hurry_n he_o be_v in_o to_o relieve_v the_o animal_n they_o by_o their_o springiness_n fling_v up_o and_o down_o with_o great_a vigour_n this_o make_v convulsive_a motion_n have_v great_a strength_n 14._o the_o body_n under_o this_o contraction_n be_v manifest_o shrink_v by_o measure_n especial_o when_o the_o sensation_n be_v very_o grievous_a but_o most_o of_o all_o if_o they_o cause_v a_o general_a convulsion_n which_o i_o manifest_o observe_v in_o a_o little_a bitch_n that_o be_v convulsive_a all_o over_o for_o three_o hour_n and_o be_v just_a expire_n when_o i_o give_v she_o the_o sal_fw-la volat._n oleo_n of_o opium_n which_o perfect_o restore_v she_o by_o relax_v the_o vessel_n some_o may_v think_v it_o strange_a that_o nature_n shall_v contrive_v a_o more_o nice_a and_o smart_a sensation_n which_o the_o contraction_n of_o the_o vessel_n of_o the_o animal_n spirit_n must_v cause_v by_o compress_v they_o etc._n etc._n in_o pain_n and_o by_o it_o which_o become_v so_o much_o the_o more_o acute_a whereas_o one_o will_v judge_v that_o nature_n will_v rather_o contrive_v its_o ease_n than_o improve_v its_o smart_n you_o be_v to_o know_v that_o the_o pain_n be_v in_o order_n to_o relieve_v the_o animal_n by_o exciting_a all_o its_o power_n to_o defend_v expel_v or_o reject_v the_o cause_n and_o that_o without_o a_o grievous_a sensation_n the_o sensitive_a soul_n be_v neither_o mind_v nor_o excite_v to_o do_v it_o and_o the_o more_o the_o pain_n be_v the_o more_o it_o be_v stir_v up_o to_o self-preservation_n and_o as_o be_v show_v the_o more_o vigorous_a do_v its_o motion_n grow_v by_o the_o compression_n of_o the_o elastic_a spirit_n to_o perform_v that_o work_n so_o nature_n not_o regard_v the_o pain_n which_o be_v rather_o for_o good_a as_o much_o as_o take_v away_o the_o cause_n advance_v that_o for_o this_o purpose_n like_o a_o wise_a physician_n who_o find_v a_o grievance_n at_o stomach_n not_o sufficient_a to_o excite_v effectual_a vomit_v to_o throw_v away_o the_o grieve_v cause_n add_v to_o the_o grievance_n by_o give_v a_o vomit_n which_o because_o as_o be_v say_v nature_n be_v proportionable_o excite_v to_o and_o invigorate_v for_o self-preservation_n sufficient_o solicit_v and_o enable_v it_o by_o a_o strong_a contraction_n to_o reject_v the_o grieve_v matter_n as_o the_o great_a the_o relaxation_n be_v the_o more_o be_v the_o rest_n of_o all_o part_n and_o the_o weak_a the_o animal_n spirit_n because_o less_o compress_v the_o gentle_a be_v all_o motion_n as_o you_o see_v in_o sleep_n consequent_o the_o less_o be_v the_o expense_n of_o spirit_n so_o that_o in_o sleep_n we_o generate_v more_o than_o we_o spend_v and_o be_v thereby_o recruit_v so_o the_o more_o the_o contraction_n be_v the_o more_o violent_a be_v the_o motion_n of_o the_o heart_n intestine_n and_o of_o all_o part_n and_o consequent_o the_o expense_n of_o spirit_n be_v the_o great_a therefore_o it_o can_v be_v no_o wonder_n that_o contraction_n do_v cause_n great_a commotion_n of_o spirit_n diary_n fever_n etc._n etc._n when_o you_o consider_v 1._o that_o the_o sensitive_a soul_n be_v by_o the_o grievous_a sensation_n etc._n etc._n that_o cause_n they_o put_v upon_o a_o great_a fret_v concern_v and_o hurry_v to_o defend_v the_o animal_n and_o lay_v about_o he_o all_o manner_n of_o way_n for_o self-preservation_n 2._o that_o the_o animal_n spirit_n be_v by_o mean_n of_o great_a compression_n cause_v by_o the_o defensive_a contraction_n in_o a_o very_a forcible_a springiness_n which_o cause_v all_o the_o action_n that_o be_v continual_a involuntary_a and_o of_o course_n to_o be_v perform_v with_o great_a violence_n proportionable_a to_o its_o compress_a elasticity_n beside_o that_o 3._o the_o systole_n of_o the_o heart_n be_v oftener_o repeat_v all_o which_o conspire_v to_o cause_v great_a commotion_n upon_o grievous_a sensation_n whereby_o diary_n fever_n etc._n etc._n be_v cause_v which_o be_v easy_o and_o natural_o cure_v by_o sleep_n or_o relaxation_n at_o present_a compose_v and_o quiet_v those_o perturbation_n who_o know_v though_o it_o be_v not_o my_o business_n to_o discuss_v it_o at_o present_a but_o that_o the_o contraction_n in_o the_o cold_a fit_n of_o ague_n have_v a_o great_a hand_n in_o cause_v the_o hot_a one_o how_o otherwise_o shall_v opium_n by_o only_o take_v away_o the_o grievous_a sensation_n of_o the_o cold_a fit_n take_v off_o or_o prevent_v the_o hot_a fit_n also_o but_o of_o this_o in_o my_o often-mentioned_n tract_n though_o not_o so_o often_o as_o it_o grieve_v i_o that_o it_o be_v not_o publish_v how_o reasonable_o may_v we_o now_o expect_v that_o pleasant_a sensation_n may_v cause_v quite_o contrary_a effect_n to_o that_o of_o grievous_a sensation_n viz._n relaxation_n and_o all_o its_o effect_n
sect._n 7._o aph._n 6._o reddit_fw-la liberam_fw-la perspirationem_fw-la quam_fw-la animi_fw-la consolatio_fw-la aut_fw-la voluptas_fw-la &_o aph._n 19_o animi_fw-la consolatio_fw-la quacunque_fw-la de_fw-la causâ_fw-la aperit_fw-la meatus_fw-la &_o largam_fw-la perspirationem_fw-la facit_fw-la now_o you_o may_v perceive_v why_o opium_n and_o good_a cordial_n do_v moderate_a flux_n by_o stool_n even_o before_o they_o be_v out_o of_o the_o stomach_n because_o the_o pleasure_n there_o cause_v relax_n all_o part_n and_o thereby_o cause_v a_o expansion_n of_o the_o animal_n spirit_n the_o sense_n of_o the_o irritation_n be_v lose_v because_o the_o expand_v spirit_n can_v carry_v the_o impression_n smart_o to_o the_o sensitive_a soul_n which_o must_v be_v to_o cause_v a_o sense_n of_o irritation_n or_o grievous_a sensation_n by_o the_o same_o reason_n only_o warm_a trencher_n apply_v to_o the_o belly_n or_o sit_v upon_o a_o warm_a stool_n etc._n etc._n moderate_v a_o looseness_n because_o the_o pleasure_n of_o the_o warmth_n relax_n and_o so_o take_v away_o a_o sense_n of_o the_o irritation_n by_o the_o aforesaid_a expansion_n of_o the_o spirit_n 12._o i_o have_v just_a now_o show_v how_o it_o promote_v insensible_a perspiration_n viz._n by_o the_o relaxation_n open_v the_o pore_n and_o let_v out_o the_o fume_n which_o i_o need_v not_o have_v mention_v again_o but_o for_o order_n sake_n that_o all_o may_v thereby_o see_v that_o i_o evade_v the_o explication_n of_o no_o effect_n nor_o indeed_o need_v i_o for_o they_o be_v now_o obvious_a enough_o even_o without_o my_o explication_n to_o any_o sagacious_a person_n so_o that_o the_o plainness_n may_v give_v great_a cause_n to_o pass_v over_o some_o untouched_a than_o the_o difficulty_n but_o it_o be_v not_o sit_v that_o either_o shall_v cause_v any_o omission_n in_o such_o a_o mighty_a concern_v that_o be_v never_o explicate_v and_o scarce_o ever_o think_v possible_a 13._o opium_n prevent_v shivering_n in_o ague_n fit_n because_o that_o for_o the_o reason_n aforesaid_a it_o take_v away_o the_o sense_n of_o the_o irritate_v humour_n that_o cause_v they_o 14._o it_o prevent_v and_o cure_v cold_n by_o the_o relaxation_n that_o its_o pleasure_n cause_n whereby_o the_o pore_n be_v keep_v very_o open_a and_o perspiration_n as_o be_v show_v promote_v beside_o that_o it_o prevent_v the_o sensation_n of_o hinder_v it_o to_o constringe_v the_o pore_n by_o cause_v a_o grievous_a sensation_n 15._o it_o cause_v a_o large_a and_o slow_a pulse_n because_o of_o the_o relaxation_n that_o the_o intense_a and_o continual_a pleasure_n cause_n by_o which_o the_o artery_n be_v widen_v and_o the_o motion_n make_v slow_a 1._o because_o the_o animal_n spirit_n be_v weaken_v by_o the_o relaxation_n of_o their_o vessel_n and_o their_o expansion_n thereupon_o 2._o because_o the_o sense_n of_o irritation_n by_o which_o the_o heart_n be_v solicit_v to_o move_v fast_o be_v lose_v 16._o it_o cause_v dryness_n in_o the_o mouth_n as_o sleep_n do_v 1._o because_o the_o dilatation_n of_o the_o glandule_n by_o the_o relaxation_n detain_v and_o suspend_v the_o humour_n and_o 2._o because_o the_o sensation_n be_v lessen_v the_o membrane_n that_o include_v the_o salival_n glandule_n be_v not_o irritate_v to_o contraction_n to_o squeeze_v out_o the_o saliva_n or_o spital_n 3._o because_o the_o pulse_n be_v slow_a to_o cause_v a_o extrusion_n of_o the_o humour_n 17._o it_o have_v most_o effect_n in_o warm_a and_o moist_a wether_n because_o both_o warmth_n and_o moisture_n promote_v relaxation_n by_o which_o opium_n do_v upon_o the_o account_n of_o the_o pleasure_n it_o cause_v perform_v its_o effect_n 18._o it_o have_v more_o effect_n upon_o fine_a and_o lax_n texture_n for_o the_o same_o reason_n and_o because_o their_o sensation_n be_v more_o nice_a and_o affect_v more_o with_o please_a or_o grieve_v thing_n therefore_o it_o affect_v child_n and_o woman_n especial_o the_o nice_n and_o delicate_a more_o than_o man_n which_o may_v be_v the_o reason_n why_o woman_n do_v not_o use_v opium_n in_o the_o eastern_a country_n as_o much_o as_o men._n 19_o it_o cause_v a_o efflorescence_n or_o redness_n of_o the_o skin_n as_o sleep_n or_o wine_n do_v because_o the_o skin_n be_v relax_v admit_v the_o blood_n to_o come_v into_o it_o very_o free_o as_o cold_a fear_v etc._n etc._n contract_v the_o part_n of_o the_o skin_n repel_v it_o or_o squeeze_v it_o out_o or_o back_o again_o thus_o person_n that_o drink_v much_o get_v red_a nose_n by_o frequent_a relaxation_n of_o the_o skin_n which_o widen_v the_o road_n of_o the_o blood_n more_o and_o more_o hence_o it_o be_v that_o the_o bag_n at_o a_o turky-cock_n neck_n be_v red_a when_o he_o be_v please_v and_o soon_o pale_a again_o when_o displease_v 20._o it_o affect_v the_o genus_fw-la nervosum_fw-la or_o animal_n spirit_n which_o be_v a_o common_a observation_n more_o than_o the_o blood_n because_o it_o operate_v by_o affect_v sensation_n wherein_o the_o nerve_n and_o membrane_n be_v most_o concern_v and_o not_o by_o alter_v the_o blood_n to_o which_o it_o bear_v no_o proportion_n to_o cause_v any_o remarkable_a effect_n note_v how_o plain_o this_o concession_n of_o all_o author_n confirm_v what_o i_o say_v viz._n that_o it_o do_v not_o operate_v as_o a_o alterative_a of_o the_o blood_n etc._n etc._n but_o by_o affect_v sensation_n as_o i_o have_v prove_v 21._o it_o increase_v seed_n in_o some_o measure_n because_o it_o administer_v a_o sal-volatile-oleosum_a of_o the_o same_o nature_n with_o it_o and_o by_o its_o titillation_n solicit_v and_o invite_v the_o send_n of_o its_o matter_n that_o way_n as_o be_v observable_a in_o such_o as_o use_v much_o titillation_n but_o to_o speak_v plain_o and_o mechanical_o i_o think_v that_o this_o main_o happen_v because_o of_o the_o relaxation_n of_o the_o part_n admit_v as_o be_v say_v of_o the_o efflorescence_n of_o the_o skin_n by_o relaxation_n the_o blood_n or_o material_n of_o seed_n more_o free_o into_o the_o testicle_n and_o all_o the_o seminary_n vessel_n especial_o be_v that_o the_o titillation_n cause_v a_o ostener_o empty_v of_o the_o same_o in_o order_n to_o receive_v those_o material_n with_o less_o opposition_n for_o quod_fw-la intus_fw-la est_fw-la prohibet_fw-la alienum_fw-la that_o be_v what_o be_v within_o hinder_v the_o entrance_n of_o other_o matter_n nothing_o can_v receive_v more_o than_o what_o it_o can_v contain_v but_o what_o be_v often_o empty_v can_v successive_o receive_v much_o 22._o it_o cause_v a_o great_a promptitude_n to_o venery_n erection_n etc._n etc._n especial_o if_o the_o do_v be_v large_a than_o ordinary_a because_o be_v of_o the_o same_o principle_n with_o animal_n seed_n and_o in_o all_o probability_n somewhat_o more_o titillate_v and_o of_o like_a principle_n though_o more_o gentle_a than_o cantharides_n it_o must_v high_o titillate_v those_o part_n and_o consequent_o cause_v a_o great_a promptitude_n to_o venery_n chap._n xviii_o the_o explication_n of_o the_o frequent_a though_o not_o constant_a effect_n of_o opium_n in_o a_o moderate_a do_v 1._o it_o cause_v sleep_n because_o it_o high_o dispose_v thereto_o by_o the_o relaxation_n that_o its_o pleasure_n cause_n thus_o music_n agreeable_a frication_n and_o many_o other_o pleasure_n nay_o all_o that_o be_v consistent_a with_o lie_v or_o sit_v still_o and_o silent_a incline_v we_o to_o sleep_n but_o none_o can_v compare_v with_o the_o sweet_a continual_a and_o transcendent_a pleasure_n of_o opium_n that_o we_o carry_v along_o with_o we_o for_o many_o hour_n whereas_o other_o pleasure_n be_v either_o remiss_a or_o interrupt_v or_o transient_a in_o their_o nature_n for_o continuance_n in_o gentle_a pleasure_n as_o the_o fall_n of_o water_n whistle_v of_o wind_n effect_n much_o towards_o sleep_n so_o intenseness_n do_v also_o though_o momentary_a as_o that_o of_o venus_n how_o much_o than_o must_v a_o continual_a and_o intense_a pleasure_n cause_n it_o especial_o when_o rest_n silence_n etc._n etc._n be_v add_v thereto_o note_v that_o sleep_n be_v so_o far_o from_o be_v a_o property_n of_o opium_n that_o it_o do_v not_o belong_v to_o it_o omni_n soli_fw-la or_o semper_fw-la yet_o people_n have_v general_o look_v upon_o sleep_n as_o such_o which_o cause_v many_o error_n 2._o it_o cause_v pleasant_a dream_n because_o the_o very_a sleep_n be_v cause_v and_o continue_v by_o pleasure_n when_o it_o be_v by_o opium_n which_o pleasure_n be_v all_o the_o time_n we_o sleep_v within_o we_o must_v needs_o suggest_v pleasant_a dream_n or_o none_o for_o how_o can_v sad_a and_o melancholy_a dream_n seize_v one_o that_o be_v in_o a_o gay_a and_o pleasant_a condition_n as_o far_o as_o one_o in_o sleep_n be_v capable_a thereof_o 3._o it_o stop_v vomit_v 1._o as_o it_o do_v other_o flux_n by_o take_v away_o the_o sense_n of_o irritation_n 2._o by_o high_o please_v and_o thereby_o quiet_v and_o compose_v the_o commotion_n of_o the_o stomach_n 3._o by_o relax_v it_o which_o oppose_v the_o
and_o motion_n fail_v together_o of_o the_o great_a perspiration_n and_o all_o other_o effect_n of_o relaxation_n in_o such_o syncopes_fw-la or_o leipothymy_n in_o a_o yet_o high_o degree_n than_o in_o sleep_n wherein_o the_o sensitive_a soul_n do_v not_o quite_o let_v go_v the_o reign_v of_o contraction_n as_o appear_v by_o the_o motion_n that_o remain_v as_o of_o the_o heart_n intestine_n etc._n etc._n though_o far_o more_o remiss_a in_o sleep_n than_o in_o a_o wake_v state_n note_v that_o such_o leipothymy_n be_v as_o be_v hint_v of_o the_o same_o nature_n as_o sleep_n be_v but_o that_o they_o be_v sudden_a more_o profound_a and_o not_o so_o usual_a natural_a and_o of_o course_n as_o sleep_n be_v which_o make_v they_o more_o amaze_a and_o surprise_v therefore_o it_o follow_v that_o they_o be_v as_o sleep_n be_v a_o mean_n of_o recruit_v when_o all_o work_n and_o tug_v by_o defensive_a contraction_n fail_v and_o so_o the_o last_o refuge_n of_o the_o sensitive_a soul_n when_o overtired_n in_o order_n to_o recover_v strength_n for_o a_o fresh_a engagement_n with_o the_o enemy_n as_o be_v tire_v at_o night_n the_o sensitive_a soul_n loosen_v the_o rign_n of_o contraction_n to_o enable_v he_o the_o better_a to_o fall_v to_o his_o work_n the_o next_o day_n this_o you_o will_v find_v by_o all_o reason_n and_o experience_n to_o be_v the_o true_a state_n of_o leipothymy_n upon_o grievance_n and_o fatigue_n though_o not_o hitherto_o mind_v that_o i_o know_v of_o many_o true_a and_o useful_a consequence_n do_v hence_o follow_v as_o that_o we_o be_v not_o always_o to_o disturb_v they_o or_o put_v they_o out_o of_o these_o recruit_v leipothymy_n by_o grievous_a mean_n as_o pricking_n pinch_n etc._n etc._n but_o only_o by_o cordial_n and_o refresh_a thing_n as_o you_o will_v treat_v a_o person_n much_o tire_v or_o by_o let_v they_o take_v their_o nap_n if_o i_o may_v so_o call_v it_o if_o there_o be_v not_o very_o eminent_a danger_n but_o it_o be_v endless_a and_o beside_o my_o purpose_n to_o make_v a_o particular_a discourse_n of_o this_o matter_n which_o will_v belong_v more_o proper_o to_o my_o tract_n of_o animal_n mechanism_n 14._o death_n happen_v sometime_o though_o very_o rare_o and_o that_o in_o very_o weak_a people_n that_o take_v little_a or_o no_o sustenance_n because_o either_o when_o fall_v into_o such_o syncopes_fw-la they_o never_o come_v out_o of_o they_o by_o reason_n that_o they_o have_v not_o within_o they_o wherewith_o to_o recruit_v their_o spirit_n or_o that_o opium_n take_v they_o much_o spend_v and_o tire_v with_o distemper_n cause_n as_o in_o weak_a and_o weary_a people_n a_o most_o profound_a sopor_fw-la which_o not_o recruit_v they_o who_o take_v or_o digest_v no_o sustenance_n they_o must_v rather_o grow_v weak_a and_o weak_a for_o somewhat_o be_v spend_v while_o we_o live_v and_o consequent_o the_o sleep_n or_o sopor_fw-la more_o and_o more_o profound_a till_o they_o sleep_v their_o last_o for_o want_v of_o some_o recruit_v which_o be_v the_o very_a thing_n that_o natural_o lessen_v sleep_n and_o awake_v we_o when_o there_o be_v no_o other_o apparent_a cause_n for_o as_o the_o be_v tire_v and_o want_v of_o recruit_v cause_n sleep_v so_o the_o have_v it_o cause_v wake_v or_o which_o be_v the_o same_o in_o effect_n no_o far_o need_v of_o relaxation_n for_o recruit_n sake_n so_o that_o the_o sensitive_a soul_n fall_v to_o his_o useful_a work_n of_o vigilative_a contraction_n for_o sense_n and_o motion_n sake_n 15._o it_o sometime_o cause_n purge_v which_o happen_v as_o far_o as_o i_o have_v observe_v or_o can_v learn_v only_o when_o it_o be_v give_v in_o a_o good_a quantity_n to_o person_n of_o a_o strong_a digestion_n or_o canine_a appetite_n the_o case_n be_v thus_o when_o person_n that_o be_v of_o a_o strong_a digestion_n take_v a_o resinous_n opiate_n in_o good_a quantity_n they_o do_v in_o great_a measure_n by_o their_o fix_a salt_n at_o stomach_n and_o strong_a digestion_n subdue_v the_o volatility_n of_o the_o opium_n and_o dissolve_v its_o rosin_n which_o then_o as_o acrimonious_a rosin_n or_o vomit_n subdue_v by_o fix_a salt_n use_v to_o do_v cause_v purge_v hence_o it_o be_v that_o it_o general_o if_o not_o always_o purge_v dog_n and_o people_n of_o a_o high_a canine_a appetite_n and_o that_o sometime_o meet_v such_o fix_a salt_n it_o purge_v the_o consumptive_a bartholine_n say_v that_o mandrake_n juice_n purge_v when_o it_o meet_v with_o acrimonious_a fix_a salt_n erastus_n and_o quercelan_n do_v agree_v that_o it_o have_v a_o purgative_n quality_n but_o that_o it_o do_v not_o always_o exert_v it_o 1._o because_o it_o take_v away_o the_o sense_n of_o irritation_n 2._o because_o it_o be_v give_v in_o too_o small_a a_o quantity_n the_o reason_n be_v just_a and_o right_a and_o not_o only_o consistent_a with_o but_o confirm_v what_o i_o say_v note_v that_o this_o be_v not_o intend_v of_o the_o purge_v that_o happen_v after_o the_o declination_n of_o its_o operation_n which_o be_v as_o you_o will_v find_v from_o another_o cause_n therefore_o this_o do_v not_o smell_v of_o the_o opium_n as_o the_o other_o do_v because_o it_o be_v past_a and_o go_v before_o that_o in_o the_o declination_n happen_v of_o which_o more_o in_o its_o proper_a place_n 16._o it_o raise_v and_o revive_v some_o person_n that_o be_v almost_o expire_a in_o two_o case_n one_o be_v when_o such_o as_o have_v be_v use_v to_o take_v it_o be_v even_o expire_a for_o want_n of_o it_o of_o which_o more_o hereafter_o the_o other_o case_n be_v when_o violent_a contraction_n as_o from_o pain_n cold_a vomit_n and_o grievous_a passion_n as_o terror_n etc._n etc._n be_v the_o cause_n that_o people_n be_v almost_o expire_a for_o it_o take_v off_o the_o contraction_n by_o relax_v etc._n etc._n 17._o it_o stay_v very_o long_o at_o stomach_n when_o the_o rosin_n thereof_o stick_v to_o the_o stomach_n and_o be_v there_o detain_v beside_o that_o the_o stomach_n be_v relax_v and_o have_v little_a sense_n or_o motion_n as_o in_o sleep_n do_v not_o soon_o digest_v it_o or_o discharge_v it_o it_o be_v fine_a in_o this_o case_n and_o all_o other_o to_o observe_v how_o sensation_n and_o motion_n go_v hand_n in_o hand_n keep_v equal_a pace_n and_o equal_a proportion_n as_o it_o plain_o must_v be_v by_o the_o principle_n of_o relaxation_n and_o contraction_n which_o i_o have_v state_v and_o prove_v 18._o it_o cause_v stoppage_n of_o urine_n sometime_o especial_o in_o old_a people_n by_o over_o relax_v and_o cause_v a_o kind_n of_o a_o temporary_a palsy_n of_o the_o bladder_n as_o be_v show_v and_o take_v away_o the_o sense_n of_o the_o irritation_n of_o the_o urine_n which_o shall_v contract_v the_o bladder_n to_o squeeze_v it_o out_o by_o which_o mean_v it_o happen_v sometime_o that_o the_o bladder_n come_v to_o be_v so_o over_o extend_v beyond_o its_o due_a tone_n that_o they_o can_v contract_v it_o to_o make_v water_n in_o all_o which_o case_n strong_a contracter_n as_o cold_a terror_n etc._n etc._n immediate_o cure_v they_o the_o very_a put_v the_o scrotum_fw-la to_o the_o edge_n of_o a_o cold_a chamberpot_n have_v effect_v it_o several_a time_n by_o my_o advice_n though_o if_o need_v be_v you_o must_v come_v to_o dash_v of_o cold_a water_n upon_o the_o region_n of_o the_o bladder_n or_o pump_v on_o it_o or_o dip_v in_o it_o etc._n etc._n so_o terror_n and_o cause_v a_o very_a smart_n pain_n especial_o near_o those_o part_n will_v do_v much_o but_o cold_a be_v the_o ready_a and_o best_a remedy_n 19_o it_o sometime_o prove_v dangerous_a after_o great_a hemorrbage_n or_o evacuation_n as_o tapping_n in_o dropsy_n etc._n etc._n because_o the_o relaxation_n hinder_v the_o part_n due_o to_o contract_v upon_o what_o remain_v which_o may_v cause_v great_a mischief_n as_o discontinuation_n of_o motion_n etc._n etc._n thus_o have_v you_o all_o the_o constant_a frequent_a and_o rare_a effect_n of_o opium_n take_v internal_o in_o a_o moderate_a do_v so_o natural_o easy_o plain_o and_o mechanical_o explicate_v that_o people_n may_v in_o my_o judgement_n more_o admire_v how_o all_o fail_v of_o discover_v the_o manner_n of_o their_o production_n than_o that_o i_o find_v it_o as_o man_n be_v apt_a to_o think_v of_o the_o circulation_n of_o the_o blood_n which_o now_o as_o i_o hope_v the_o effect_n of_o opium_n do_v seem_v very_o obvious_a both_o which_o case_n be_v to_o i_o very_o strong_a argument_n of_o a_o be_v that_o rule_n and_o dispose_n darken_v and_o illuminate_v etc._n etc._n as_o he_o please_v when_o i_o consider_v that_o both_o the_o circulation_n of_o the_o blood_n and_o the_o cause_n of_o the_o operation_n of_o opium_n viz._n pleasure_n at_o stomach_n etc._n etc._n fall_v under_o the_o sense_n of_o many_o million_o who_o in_o one_o case_n see_v the_o blood_n move_v and_o in_o the_o other_o feel_v
principle_n of_o motion_n by_o which_o all_o ill_a matter_n be_v effective_o subdue_v when_o they_o act_v with_o alacrity_n and_o vigour_n they_o be_v the_o principal_a agent_n and_o we_o physician_n but_o as_o be_v say_v minister_n or_o as_o handmaid_n to_o offer_v or_o hand_n good_a matter_n medicament_n or_o instrument_n to_o those_o principal_a agent_n of_o nature_n and_o that_o this_o sal-volatile-oleosum_a of_o opium_n be_v the_o most_o proper_a matter_n or_o medicament_n we_o can_v put_v into_o nature_n hand_n so_o invigorate_v appear_v manifest_o in_o that_o 5._o its_o principle_n be_v the_o most_o agreeable_a to_o the_o best_a noble_a most_o active_a and_o predominant_a principle_n of_o our_o body_n as_o have_v be_v prove_v most_o evident_o plene_fw-la &_o plane_n nor_o be_v it_o only_o agreeable_a but_o 6._o more_o vigorous_a and_o powerful_a to_o actuate_v reduce_v alter_v or_o exalt_v our_o principle_n according_a to_o the_o direction_n of_o our_o invigorated_a nature_n or_o sensitive_a soul_n and_o spirit_n which_o have_v so_o convenient_a a_o instrument_n and_o high_o qualify_v a_o matter_n will_v soon_o alter_v the_o perverse_a renew_v the_o decay_a acuate_v the_o dull_a and_o elevate_v the_o depress_v effete_a and_o pall_a humour_n of_o our_o body_n especial_o see_v 7._o that_o the_o sal-volatile-oleosum_a of_o opium_n be_v so_o agreeable_a and_o powerful_a must_v be_v the_o great_a resolver_n of_o humour_n that_o can_v be_v imagine_v for_o all_o resolution_n be_v by_o a_o agreement_n of_o particle_n which_o make_v they_o easy_o miscible_a insinuate_v into_o and_o penetrate_v each_o other_o especial_o if_o one_o be_v somewhat_o more_o vigorous_a and_o penetrate_a than_o the_o other_o as_o the_o sal-volatile-oleosum_a have_v be_v plain_o prove_v to_o be_v thus_o it_o be_v that_o all_o menstruum_n do_v so_o resolve_v thing_n of_o their_o own_o nature_n and_o so_o purify_v and_o cleanse_v they_o by_o take_v to_o themselves_o what_o be_v mere_o and_o pure_o of_o the_o same_o nature_n and_o reject_v or_o let_v go_v their_o hold_n of_o what_o be_v otherwise_o where_o it_o be_v worth_a note_n how_o upon_o the_o account_n of_o the_o intimate_a combination_n and_o union_n of_o the_o volatile_a salt_n and_o oily_a part_n in_o our_o panacea_fw-la it_o be_v dissolvable_a in_o all_o menstruum_n and_o consequent_o a_o universal_a resolvent_fw-la of_o all_o the_o humour_n of_o our_o body_n which_o its_o external_a resolve_v of_o all_o humour_n and_o tumor_n do_v also_o prove_v now_o if_o it_o be_v such_o a_o resolver_n of_o which_o there_o be_v no_o place_n to_o doubt_v then_o as_o claudius_n de_fw-fr la_fw-fr courvee_n say_v it_o must_v excel_v all_o thing_n in_o alter_v and_o reduce_v all_o the_o humour_n of_o our_o body_n to_o a_o good_a and_o agreeable_a condition_n nor_o do_v it_o only_o thus_o resolve_v they_o and_o thereby_o separate_v as_o be_v say_v the_o good_a from_o the_o bad_a but_z 8._o when_o it_o have_v so_o do_v it_o by_o the_o amicable_a agreeableness_n of_o its_o sal-volatile-oleosum_a compose_v faculty_n strict_a combination_n of_o its_o principle_n join_v to_o concentrate_n congregate_n and_o as_o it_o be_v cement_v the_o best_a and_o most_o agreeable_a into_o a_o close_a union_n and_o firm_a texture_n by_o as_o be_v say_v the_o direction_n of_o invigorated_a nature_n which_o be_v of_o itself_o the_o good_a be_v once_o separate_v from_o the_o bad_a high_o sufficient_a without_o any_o other_o help_v to_o unite_v part_n so_o agreeable_a and_o of_o themselves_o incline_v to_o unite_v and_o combine_v though_o all_o tho_o part_n of_o opium_n like_o those_o of_o the_o great_a dissolvent_a be_v go_v and_o when_o that_o be_v do_v 9_o the_o high_a discussive_a quality_n of_o the_o sal-volatile-oleosum_a must_v be_v very_o effectual_a for_o the_o difflation_n and_o discussion_n of_o the_o sever_a effete_a particle_n which_o must_v be_v high_o assist_v and_o improve_v by_o the_o brisk_a and_o cheerful_a motion_n of_o nature_n viz._n the_o sensitive_a soul_n and_o spirit_n so_o as_o be_v aforesaid_a invigorate_v nor_o be_v this_o all_o but_o to_o complete_a and_o perfect_a the_o operation_n 10._o it_o lay_v open_a all_o the_o pore_n of_o the_o body_n as_o have_v be_v demonstrate_v 〈◊〉_d they_o out_o and_o give_v the_o ill_a particle_n their_o â—inal_n exit_fw-la by_o the_o most_o natural_a and_o plentiful_a way_n of_o evacuation_n leave_v the_o body_n free_a from_o all_o miasm_n and_o impurity_n 11._o i_o have_v sufficient_o show_v how_o unalterable_a it_o be_v in_o itself_o chap._n 15._o so_o that_o like_o the_o liquor_n alcahest_fw-mi it_o be_v not_o make_v to_o be_v subdue_v but_o to_o subdue_v and_o resolve_v humour_n now_o what_o can_v be_v require_v more_o in_o a_o medicament_n and_o how_o can_v the_o sensitive_a soul_n and_o spirit_n or_o nature_n so_o invigorate_v and_o endue_v with_o all_o euphory_n and_o cheerfulness_n by_o this_o glorious_a medicament_n who_o principle_n be_v not_o only_o agreeable_a to_o our_o noble_a one_o but_o more_o powerful_a and_o intimate_o combine_v so_o resolve_v of_o humour_n ready_a to_o unite_v the_o good_a and_o to_o discuss_v the_o bad_a and_o carry_v they_o off_o by_o the_o pore_n ever_o fail_v be_v due_o administer_v of_o good_a effect_n in_o alter_v all_o the_o humour_n of_o our_o body_n hypocrates_n in_o his_o book_n de_fw-fr nature_n hominis_fw-la state_n the_o cause_n of_o disease_n to_o be_v a_o disgregation_n of_o humour_n by_o which_o he_o seem_v to_o imply_v that_o the_o power_n of_o congregate_a and_o concentrate_v of_o humour_n be_v sufficient_a to_o accomplish_v a_o panacea_fw-la which_o be_v but_o one_o single_a qualification_n in_o eleven_o of_o our_o sal-volatile-oleosum_a though_o this_o alone_a as_o be_v experience_v even_o in_o common_a preparation_n of_o opium_n suffice_v very_o often_o to_o cure_v disease_n by_o compose_v commotion_n as_o in_o diary_n fever_n from_o perturbation_n etc._n etc._n thus_o the_o bitter_a and_o firm_a texture_v cortex_fw-la as_o i_o have_v show_v in_o my_o book_n de_fw-fr febribus_fw-la intermittentibus_fw-la take_v off_o ague_n fit_v by_o re-combining_a the_o segregated_a humour_n with_o the_o blood_n which_o it_o sudden_o do_v leave_v a_o disposition_n in_o the_o blood_n when_o ever_o it_o meet_v with_o a_o segregate_a cause_n as_o purge_v violent_a motion_n insolation_n intemperate_a drink_v etc._n etc._n to_o a_o relapse_n by_o a_o second_o separation_n of_o the_o morbid_v matter_n from_o it_o as_o you_o have_v it_o more_o at_o large_a in_o my_o say_a book_n p._n 166_o 167_o etc._n etc._n 242_o 243_o etc._n etc._n where_o you_o may_v see_v how_o opiate_n conduce_v very_o much_o to_o a_o speedy_a cure_n by_o the_o cortex_fw-la by_o compose_v etc._n etc._n martianus_n say_v coâ—m_fw-la de_fw-fr locis_fw-la in_o homine_fw-la p._n 76._o opium_n sist_z it_o &_o prohibet_fw-la humorum_fw-la disgregationem_fw-la that_o be_v opium_n hinder_v disgregation_n of_o humour_n now_o you_o may_v perceive_v the_o true_a qualification_n of_o a_o sal-volatile-oleosum_a so_o much_o seek_v for_o by_o the_o learned_a as_o a_o panacea_fw-la and_o how_o far_o the_o common_a one_o that_o be_v sell_v in_o the_o apothecary_n shop_n be_v from_o be_v such_o silvius_n indeed_o have_v a_o excellent_a one_o with_o which_o he_o do_v many_o and_o great_a cure_n which_o be_v consider_v have_v he_o not_o confess_v his_o ignorance_n of_o the_o cause_n of_o the_o effect_n of_o opium_n and_o the_o narrative_a he_o make_v of_o its_o virtue_n and_o performance_n in_o his_o preface_n to_o the_o first_o book_n of_o his_o praxis_fw-la and_o that_o he_o delight_v so_o much_o in_o the_o use_n of_o opium_n even_o when_o he_o be_v young_a that_o he_o be_v call_v by_o the_o name_n of_o doctor_n opiatus_fw-la and_o that_o he_o declare_v no_o oil_n be_v add_v in_o its_o preparation_n and_o that_o it_o be_v intimate_v that_o the_o oil_n and_o volatile_a part_n be_v strict_o combine_v will_v have_v make_v i_o suspect_n that_o it_o be_v the_o sal-volatile-oleosum_a of_o opium_n that_o he_o use_v which_o if_o it_o be_v not_o i_o dare_v be_v confident_a that_o notwithstanding_o all_o its_o excellency_n it_o be_v not_o as_o good_a i_o be_o very_a well_o satisfy_v that_o a_o true_a and_o consummate_v sal-volatile-oleosum_a be_v not_o to_o be_v make_v bare_o by_o art_n enquirer_n may_v have_v better_a success_n if_o they_o seek_v it_o among_o the_o natural_a tribe_n of_o bitter_a plant_n that_o be_v agreeable_a to_o the_o stomach_n which_o have_v all_o in_o they_o a_o sal-volatile-oleosum_a but_o how_o to_o pick_v and_o cull_v be_v i_o think_v best_o see_v by_o the_o requisite_a qualification_n of_o a_o panacea_fw-la that_o i_o have_v state_v there_o have_v be_v many_o in_o who_o hand_n bitter_a thing_n have_v be_v as_o a_o panacea_fw-la one_o in_o germany_n cure_v most_o disease_n with_o wild_a sage_n some_o have_v do_v great_a thing_n with_o agrimony_n other_o
looseness_n cause_v by_o the_o humour_n of_o the_o body_n or_o thing_n give_v as_o diarrheâ—s_n dysentery_n artificial_a purge_v iliack_a passion_n cholera_fw-la morbus_fw-la after_o the_o humour_n be_v somewhat_o spend_v defluxion_n catarrh_n immoderate_a spit_n gonorrhoea_n notha_fw-la that_o be_v of_o slimy_a humour_n by_o reason_n of_o acrimony_n fluor_fw-la albus_fw-la from_o the_o like_a cause_n or_o any_o other_o flux_n of_o that_o kind_a 2._o to_o moderate_v or_o cure_v fluxâ—s_n that_o proceed_v from_o too_o much_o motion_n of_o the_o blood_n humour_n etc._n etc._n as_o hemorrhage_n at_o nose_n lung_n stomach_n by_o the_o hemorrhoid_v piss_a of_o blood_n immoderate_a flux_n of_o blood_n by_o the_o menses_fw-la lochia_n stool_n etc._n etc._n when_o they_o proceed_v from_o that_o cause_n as_o may_v also_o some_o defluxion_n 3._o to_o stop_v flux_n that_o proceed_v as_o hypocrates_n say_v from_o segregation_n of_o humour_n by_o compose_v and_o combine_v they_o from_o which_o cause_n many_o such_o flux_n as_o i_o have_v mention_v do_v happen_v but_o it_o be_v not_o advisable_v to_o use_v they_o in_o flux_n that_o be_v apparent_o or_o very_o probable_o for_o speedy_a and_o ready_a benefit_n otherwise_o as_o be_v say_v of_o pain_n use_v they_o to_o respite_n nature_n which_o they_o do_v as_o sleep_n do_v nay_o in_o many_o case_n the_o continuance_n of_o their_o use_n may_v quite_o cure_v they_o for_o the_o several_a reason_n give_v in_o the_o begin_n of_o this_o chapter_n what_o a_o pleasant_a cure_n then_o do_v some_o refuse_v that_o reject_v they_o leave_v their_o patient_n to_o be_v wear_v out_o with_o dismal_a pain_n tedious_a and_o profuse_a evacuation_n want_v of_o appetite_n and_o digestion_n the_o common_a consequence_n of_o diarrheas_n disentery_n etc._n etc._n i._o the_o form_n of_o opiate_n in_o this_o case_n shall_v general_o be_v solid_a because_o it_o stick_v better_a to_o its_o work_n whereas_o the_o fluid_n be_v more_o subject_a to_o be_v evacuate_v in_o diarrheas_n dysentery_n and_o vomit_n though_o sometime_o the_o liquid_a may_v be_v convenient_a in_o vomit_n as_o when_o that_o form_n be_v more_o agreeable_a to_o the_o stomach_n or_o that_o you_o will_v have_v a_o more_o speedy_a effect_n etc._n etc._n in_o other_o flux_n where_o the_o opiate_n be_v not_o liable_a to_o be_v evacuate_v too_o soon_o it_o be_v indifferent_a what_o form_n you_o use_v ii_o the_o do_v in_o flux_n where_o it_o be_v probable_a some_o part_n of_o the_o opiate_n may_v be_v carry_v off_o without_o effect_n as_o in_o vomit_n diarrheas_n dysentery_n choleras_fw-la etc._n etc._n the_o do_v must_v be_v general_o speak_v pretty_a large_a otherwise_o a_o moderate_a dose_n may_v serve_v in_o such_o case_n due_a consideration_n be_v to_o be_v have_v of_o what_o be_v lose_v by_o the_o evacuation_n at_o which_o you_o may_v easy_o guess_v in_o vomit_v by_o what_o come_v up_o if_o its_o colour_n smell_v taste_v be_v observe_v as_o also_o by_o the_o frequency_n and_o violence_n of_o the_o vomit_v and_o note_v how_o the_o stomach_n clear_v itself_o of_o what_o be_v inge_v by_o the_o quantity_n and_o last_o by_o the_o effect_n of_o which_o if_o what_o be_v give_v fail_n more_o of_o the_o opiate_n must_v be_v give_v by_o degree_n till_o it_o stop_v the_o vomit_v in_o some_o measure_n in_o looseness_n give_v half_a the_o first_o do_v every_o four_o hour_n till_o the_o flux_n begin_v to_o be_v moderate_v then_o be_v more_o wary_a in_o give_v it_o for_o what_o be_v afterward_o give_v may_v have_v its_o full_a effect_n therefore_o be_v very_o cautious_a by_o give_v but_o small_a quantity_n both_o in_o this_o case_n and_o in_o vomit_v when_o they_o be_v moderate_v in_o some_o degree_n because_o opiate_n than_o have_v their_o full_a effect_n without_o any_o diminution_n or_o opposition_n thereof_o in_o other_o flux_n a_o moderate_a dose_n may_v serve_v as_o in_o desluxion_n catarrh_n etc._n etc._n however_o let_v the_o do_v rather_o incline_v to_o the_o high_a than_o the_o low_a and_o suffice_v if_o possible_a to_o cause_v sleep_n which_o be_v a_o great_a effect_n in_o these_o case_n iii_o the_o vehicle_n in_o vomit_v shall_v be_v small_a in_o quantity_n pleasant_a comfortable_a and_o warm_v lest_o you_o shall_v by_o either_o quantity_n or_o quality_n give_v any_o offence_n to_o the_o stomach_n please_v it_o answer_v the_o same_o intent_n with_o the_o opiate_n itself_o and_o have_v often_o good_a effect_n without_o opium_n for_o indeed_o every_o pleaser_n be_v proportionable_o a_o opiate_n and_o opium_n be_v only_o such_o in_o a_o intense_a and_o permanent_a manner_n therefore_o the_o vehicle_n must_v be_v agreeable_a as_o wine_n hippocras_n or_o wine_n burn_v with_o spice_n rosemary_n etc._n etc._n or_o the_o best_a cordial_n or_o wine_n with_o some_o 〈◊〉_d caviar_n or_o anchovis_n or_o a_o little_a old_a châ—ese_n dissolve_v in_o it_o upon_o the_o fire_n according_a as_o the_o person_n like_v one_o or_o the_o other_o which_o last_n though_o not_o use_v in_o common_a practice_n be_v of_o very_o great_a benefit_n where_o they_o be_v please_v and_o well_o like_v of_o in_o looseness_n such_o wine_n and_o cordial_n as_o be_v subastringent_a shall_v be_v afford_v after_o the_o peccant_a matter_n be_v evacuate_v to_o comfort_v the_o bowel_n but_o the_o mention_a salt_n thing_n be_v not_o convenient_a in_o this_o case_n in_o defluxion_n incrassative_a composer_n be_v the_o best_a vehicles_n as_o emulsion_n etc._n etc._n see_v the_o vehicles_n for_o compose_v for_o they_o be_v all_o proper_a in_o this_o case_n also_o iv_o the_o time_n be_v at_o any_o hour_n when_o there_o be_v occasion_n but_o sleep_v conduce_v the_o proper_a time_n will_v be_v unless_o need_v otherwise_o require_v at_o the_o due_a and_o direct_v distance_n before_o bedtime_n v._o the_o regimen_n 1._o as_o to_o diet_n in_o vomit_n offer_v nothing_o to_o the_o stomach_n but_o such_o thing_n and_o in_o such_o quantity_n as_o be_v direct_v for_o vehicles_n only_o in_o vomit_v before_o the_o grieve_v matter_n be_v discharge_v it_o will_v be_v often_o convenient_a before_o the_o opiate_n be_v give_v to_o give_v good_a quantity_n of_o innocent_a diluter_n as_o lukewarm_a water_n plain_a or_o carduus-posset_n between_o the_o vomit_n to_o dilate_v and_o render_v the_o vomit_v more_o easy_a but_o when_o you_o will_v stop_v the_o vomit_v use_v but_o small_a quantity_n of_o such_o thing_n as_o be_v above_o direct_v for_o vehicles_n diluter_n in_o great_a quantity_n do_v also_o succeed_v very_o well_o in_o looseness_n to_o wash_v off_o the_o ill_a humour_n before_o the_o opiate_n be_v give_v and_o it_o be_v the_o best_a practice_n that_o can_v be_v but_o the_o chalybeate_a water_n be_v the_o very_o best_a for_o that_o purpose_n though_o posset_n or_o very_o thin_a chicken_n or_o mutton_n broth_n be_v useful_a for_o it_o answer_v all_o good_a intention_n it_o dilute_v and_o qualify_v the_o peccant_a humour_n strengthen_v the_o bowel_n leave_v a_o bind_a quality_n after_o the_o dilution_n be_v make_v restore_v appetite_n and_o digestion_n which_o be_v both_o much_o amiss_o in_o such_o case_n and_o add_v moisture_n to_o the_o blood_n which_o be_v under_o a_o frâ—t_n or_o febricula_fw-la for_o want_n thereof_o because_o all_o liquid_n be_v carry_v off_o by_o stool_n but_o much_o of_o this_o go_v to_o the_o blood_n where_o it_o also_o wash_v off_o ill_a saline_a particle_n so_o that_o believe_v i_o it_o be_v of_o itself_o a_o most_o complete_a and_o adequate_a remedy_n in_o such_o case_n if_o take_v to_o 3_o or_o 4_o quart_n for_o 1_o 2_o or_o 3_o day_n 1._o solid_n meat_n or_o thing_n hard_a of_o digestion_n must_v be_v avoid_v because_o the_o digestion_n be_v infirm_a but_o milks_n thicken_v with_o rice_n or_o flower_n rice_n gruâ—s_n a_o light_a bread_n or_o rice_n pudding_n jelly_n marmalet_n a_o tâ—st_n out_o of_o claret_n with_o nutmeg_n cinnamon_n and_o some_o loaf_n sugar_n emulsion_n almond_n milk_n cheesecake_n custard_n and_o all_o subastringent_a incrassative_n be_v best_a as_o also_o in_o all_o defluxion_n 2._o as_o to_o sleep_v and_o wake_v that_o be_v good_a and_o this_o bad_a 3._o as_o to_o rest_n and_o motion_n that_o be_v convenient_a this_o not_o 4._o as_o to_o passion_n the_o joyous_a be_v convenient_a the_o grievous_a not_o 5._o as_o to_o air_n the_o dry_a and_o temperate_a be_v best_a 6._o as_o to_o excretion_n and_o retention_n what_o be_v say_v above_o be_v sufficient_a save_v that_o vomit_n be_v very_o often_o convenient_a especial_o if_o the_o looseness_n be_v occasion_v by_o the_o stomach_n to_o moderate_v it_o before_o the_o opiate_n be_v give_v chap._n xxxvii_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o cause_n flux_n or_o evacuation_n as_o perspiration_n sweat_v etc._n etc._n it_o as_o be_v show_v promote_v some_o flux_n or_o evacuation_n by_o relax_v and_o open_v
or_o vapour_n do_v ready_o and_o free_o pass_v from_o the_o stomach_n to_o the_o brain_n because_o the_o gross_a fume_n as_o they_o call_v they_o of_o a_o grain_n or_o two_o of_o opium_n always_o operate_v before_o it_o be_v out_o of_o the_o stomach_n but_o they_o never_o see_v such_o fume_n pass_v nor_o their_o passage_n only_o suppose_v both_o and_o that_o mere_o upon_o a_o imagination_n that_o it_o must_v be_v so_o because_o they_o forsooth_o can_v conceive_v any_o other_o way_n by_o which_o opium_n can_v affect_v the_o head_n nerve_n etc._n etc._n while_o it_o be_v at_o stomach_n whereas_o i_o can_v and_o shall_v god_n will_v show_v they_o another_o mean_n or_o way_n to_o do_v it_o that_o be_v sensible_a and_o not_o whole_o precarious_a as_o they_o be_v and_o that_o in_o the_o mean_a manner_n because_o all_o their_o ground_n to_o suppose_v it_o be_v their_o inability_n to_o conceive_v or_o apprehend_v what_o be_v as_o i_o shall_v show_v very_o sensible_a nay_o obvious_a also_o second_o they_o suppose_v that_o such_o fume_n will_v serve_v to_o solve_v all_o the_o phoenomena_n and_o operation_n of_o opium_n whereas_o it_o be_v utter_o impossible_a they_o shall_v solve_v the_o enliven_a and_o invigorate_n effect_n thereof_o as_o have_v be_v show_v and_o shall_v be_v further_o prove_v if_o god_n permit_v it_o be_v easy_a to_o evidence_n but_o that_o it_o will_v be_v tedious_a and_o needless_a for_o their_o incompetency_n to_o solve_v the_o most_o proper_a effect_n of_o opium_n be_v more_o than_o enough_o that_o such_o fume_n or_o vapour_n can_v true_o solve_v no_o effect_n of_o opium_n unless_o it_o be_v that_o of_o death_n or_o some_o deadly_a symptom_n nay_o they_o will_v not_o solve_v the_o most_o likely_a to_o be_v cause_v by_o vapour_n viz._n sleep_v which_o all_o man_n as_o wedelius_n say_v allow_v to_o be_v the_o effect_n of_o fume_n or_o vapour_n in_o his_o opiologia_fw-la c._n 11._o p._n 35._o somnum_fw-la naturalem_fw-la say_v he_o omnes_fw-la concedunt_fw-la producere_fw-la suaviores_fw-la &_o blandas_fw-la 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d seu_fw-la vapores_fw-la primum_fw-la 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d demulcentes_fw-la qui_fw-la cum_fw-la spiritibus_fw-la animalibus_fw-la mixti_fw-la torpidos_fw-la quasi_fw-la illos_fw-la reddunt_fw-la that_o be_v all_o grant_v that_o kind_n and_o gentle_a fume_n do_v cause_n natural_a sleep_n etc._n etc._n which_o be_v most_o certain_o false_a though_o i_o very_o much_o doubt_n that_o this_o groundless_a presumption_n which_o as_o he_o intimate_v all_o embrace_n have_v be_v a_o great_a cause_n of_o this_o airy_a imagination_n of_o fume_n in_o the_o case_n of_o opium_n because_o man_n look_v upon_o sleep_n agree_v upon_o to_o be_v cause_v by_o fume_n to_o be_v the_o prime_n lead_v and_o most_o proper_a effect_n of_o opium_n which_o be_v also_o false_a it_o be_v but_o a_o mere_a accident_n as_o have_v be_v show_v and_o when_o it_o happen_v general_o require_v lie_v or_o sit_v still_o to_o assist_v it_o whereas_o the_o watch_a that_o be_v the_o effect_n of_o opium_n require_v no_o help_n and_o can_v be_v put_v off_o as_o sleep_n can_v by_o motion_n action_n etc._n etc._n notwithstanding_o all_o endeavour_n to_o the_o contrary_n now_o i_o will_v know_v of_o any_o man_n which_o be_v the_o most_o proper_a and_o natural_a effect_n of_o any_o cause_n that_o which_o nothing_o can_v hinder_v or_o that_o which_o every_o action_n can_v but_o i_o run_v too_o far_o upon_o this_o matter_n which_o belong_v more_o apt_o to_o that_o part_n of_o this_o book_n that_o explain_v all_o the_o effect_n of_o opium_n and_o so_o must_v return_v to_o that_o of_o fume_n which_o do_v not_o cause_v natural_a sleep_n as_o manifest_o appear_v 1._o because_o that_o which_o cause_v natural_a sleep_n must_v in_o all_o reason_n as_o it_o be_v always_o in_o the_o wise_a work_n of_o nature_n bear_v a_o proportion_n thereto_o but_o fume_n suppose_v their_o be_v bear_v no_o proportion_n to_o our_o sleep_n certain_o a_o work_a labourer_n that_o toil_v all_o the_o day_n must_v spend_v the_o fume_n of_o his_o body_n in_o the_o high_a degree_n and_o feed_v upon_o dry_a bread_n and_o cheese_n must_v breed_v few_o fume_n yet_o none_o sleep_v better_a or_o sweet_a than_o he_o the_o like_a be_v to_o be_v say_v of_o a_o travel_a man_n a_o tire_a person_n etc._n etc._n who_o often_o fall_v asleep_a before_o they_o eat_v or_o drink_v to_o renew_v their_o fume_n which_o they_o have_v spend_v in_o a_o extraordinary_a manner_n why_o sleep_n that_o be_v design_v for_o refreshment_n and_o recruit_v shall_v depend_v upon_o fume_n no_o man_n can_v tell_v for_o than_o our_o refreshment_n will_v whole_o depend_v thereon_o and_o no_o man_n have_v any_o recruit_v by_o sleep_n but_o in_o proportion_n thereunto_o who_o dare_v accuse_v our_o wise_a and_o good_a maker_n of_o such_o contrivance_n who_o in_o nature_n always_o proportion_n thing_n to_o the_o exigency_n thereof_o and_o therefore_o sleep_v not_o to_o fume_n but_o to_o that_o which_o be_v impair_v in_o we_o for_o want_v thereof_o which_o be_v always_o contrive_v by_o wise_a nature_n if_o you_o will_v observe_v it_o to_o be_v the_o prompt_a cause_n to_o the_o recruit_v and_o then_o proportion_n be_v due_o observe_v because_o we_o be_v prompt_v exact_o according_a to_o the_o exigence_n or_o necessity_n of_o nature_n as_o become_v the_o wisdom_n of_o our_o creator_n and_o preserver_n this_o rule_n if_o due_o attend_v to_o will_v easy_o speedy_o and_o certain_o lead_v you_o to_o the_o knowledge_n of_o the_o true_a natural_a cause_n of_o hunger_n thirst_v inclination_n to_o sleep_n and_o all_o such_o call_v for_o restauration_n all_o which_o i_o can_v soon_o satisfy_v you_o in_o but_o that_o it_o be_v not_o my_o business_n at_o present_a and_o that_o it_o will_v too_o much_o anticipate_v my_o design_a tract_n of_o animal_n mechanism_n nor_o do_v labour_v itself_o bear_v any_o exact_a proportion_n thereunto_o because_o many_o healthy_a people_n that_o be_v idle_a all_o day_n sleep_v long_o sound_o and_o sweet_o every_o night_n as_o well_o as_o labourer_n so_o that_o in_o short_a it_o must_v be_v somewhat_o that_o belong_v to_o watch_v as_o such_o for_o sleep_v general_o bear_v the_o best_a proportion_n to_o watch_v if_o we_o watch_v much_o or_o little_a our_o sleep_n bear_v some_o proportion_n thereto_o though_o there_o may_v be_v in_o this_o as_o well_o as_o in_o hunger_n thirst_v etc._n etc._n accident_n that_o cause_n the_o promptitude_n to_o be_v more_o or_o less_o and_o so_o vary_v the_o true_a natural_a proportion_n all_o which_o have_v the_o nature_n of_o disease_n as_o canine_a appetite_n coma_n caros_n preternatural_a thrists_z etc._n etc._n what_o it_o be_v that_o watch_a cause_n to_o prompt_v we_o to_o sleep_n must_v be_v some_o impair_v make_v thereby_o as_o such_o and_o not_o the_o foolish_a conceit_n of_o fume_n and_o it_o be_v easy_a for_o i_o to_o illustrate_v what_o it_o be_v but_o that_o it_o will_v require_v some_o sheet_n of_o paper_n and_o as_o i_o say_v before_o anticipate_v my_o discourse_n of_o animal_n mechanism_n which_o i_o hope_v to_o have_v publish_v before_o this_o book_n and_o will_v have_v be_v most_o convenient_a because_o the_o principle_n therein_o state_v may_v serve_v to_o explain_v the_o effect_n of_o opium_n but_o that_o the_o want_n of_o a_o few_o experiment_n have_v to_o my_o grief_n hitherto_o delay_v it_o and_o therefore_o i_o must_v be_v put_v to_o much_o trouble_v in_o this_o work_n for_o want_v thereof_o because_o i_o be_o resolve_v not_o to_o spare_v myself_o in_o order_n to_o satisfy_v the_o reader_n in_o this_o great_a and_o unexplicate_v mystery_n 2._o if_o vapour_n be_v the_o cause_n of_o natural_a sleep_n it_o be_v impossible_a that_o the_o prick_n of_o a_o pin_n or_o a_o sharp_a sound_n etc._n etc._n shall_v awake_v one_o ten_o or_o twenty_o time_n in_o a_o hour_n for_o either_o the_o prick_n must_v in_o a_o instant_n discuss_v all_o the_o fume_n in_o be_v which_o be_v impossible_a to_o be_v imagine_v and_o they_o as_o often_o return_v to_o cause_n sleep_v again_o or_o intercept_v their_o motion_n from_o the_o stomach_n to_o the_o head_n which_o no_o man_n can_v have_v any_o conception_n of_o the_o efficacy_n of_o the_o pin_n or_o sound_v so_o to_o do_v or_o they_o must_v both_o discuss_v and_o intercept_v the_o fume_n which_o indeed_o if_o the_o case_n be_v such_o will_v be_v necessary_a to_o make_v a_o clear_a awake_v which_o be_v yet_o far_o more_o unconceivable_a what_o paltry_a trifle_n do_v the_o world_n embrace_v instead_o of_o truth_n and_o reason_n 3._o several_a person_n whereof_o i_o be_o one_o do_v awake_a in_o a_o minute_n or_o two_o after_o they_o first_o fall_v asleep_a in_o bed_n at_o night_n which_o will_v be_v absolute_o impossible_a if_o fume_n cause_v sleep_n for_o the_o fume_n will_v
impossible_a it_o shall_v be_v without_o such_o disturbance_n as_o i_o mention_v will_v follow_v if_o they_o pass_v in_o the_o road_n of_o the_o spirit_n it_o be_v not_o common_a sense_n that_o such_o câ—de_a blast_n shall_v meliorate_v or_o enliven_v the_o spirit_n to_o cause_v briskness_n bravery_n serenity_n courage_n magnanimity_n as_o opium_n do_v much_o less_o if_o those_o fume_n stop_v and_o crowd_v in_o the_o brain_n and_o any_o way_n hinder_v the_o generation_n of_o animal_n spirit_n as_o the_o common_a assertion_n be_v the_o like_a be_v to_o be_v say_v of_o their_o pass_v between_o the_o pia_fw-la mater_fw-la and_o the_o medullary_a part_n of_o the_o nerve_n which_o can_v be_v allow_v because_o of_o its_o close_a adherence_n thereto_o with_o this_o addition_n that_o they_o will_v constant_o cause_v a_o violent_a headache_n which_o opium_n and_o meal_n to_o which_o fume_n be_v particular_o attribute_v do_v often_o cure_v so_o if_o they_o get_v up_o to_o the_o head_n between_o the_o pia_n and_o dura_n mater_n it_o be_v headache_n and_o not_o the_o symptom_n of_o opium_n that_o they_o will_v produce_v which_o headache_n as_o be_v say_v opium_n and_o meal_n do_v cure_v 21._o last_o if_o they_o pass_v by_o any_o mean_n quite_o on_o the_o outside_n of_o the_o nerve_n and_o their_o membrane_n viz._n the_o pia_n and_o dura_n mater_n then_o must_v they_o take_v their_o lodgement_n if_o within_o the_o skull_n between_o the_o dura_n mater_n and_o the_o skull_n and_o produce_v no_o other_o symptom_n but_o a_o headache_n which_o as_o be_v say_v opium_n and_o meal_n rather_o cure_v than_o produce_v and_o if_o without_o the_o skull_n it_o be_v quite_o beside_o the_o cushion_n and_o the_o vaporarian_n own_o intention_n for_o in_o all_o these_o last_o case_n they_o can_v not_o affect_v the_o animal_n spirit_n for_o good_a or_o evil_n many_o and_o very_o many_o thing_n may_v be_v add_v to_o show_v the_o impossibility_n inconvenience_n incoherence_n absurdity_n etc._n etc._n that_o attend_v the_o passage_n of_o the_o fume_n and_o vapour_n into_o the_o brain_n head_n etc._n etc._n 22._o i_o have_v forgotâ—_n mention_v the_o absurdity_n of_o its_o pass_v up_o at_o gullet_n and_o so_o to_o the_o head_n because_o i_o can_v not_o imagine_v that_o any_o one_o will_v be_v so_o beastly_a a_o animal_n as_o to_o belch_v up_o a_o argument_n of_o that_o kind_n consider_v our_o very_a sense_n tell_v we_o that_o what_o come_v up_o that_o way_n pass_v out_o at_o mouth_n or_o nostril_n and_o because_o if_o it_o be_v so_o the_o operation_n of_o opium_n etc._n etc._n will_v be_v in_o proportion_n to_o our_o belch_a which_o be_v ridiculous_a 23._o the_o great_a comfort_n of_o a_o cordial_n be_v at_o first_o or_o soon_o after_o it_o be_v take_v but_o if_o '_o its_o comfort_n be_v by_o fume_n or_o essluvia_n pass_v to_o the_o blood_n or_o any_o where_o beside_o the_o comfort_n will_v as_o their_o cause_n of_o fume_n do_v increase_v for_o a_o long_a time_n and_o be_v more_o after_o a_o good_a while_n than_o at_o first_o so_o 24._o if_o opium_n operate_v by_o fume_n while_o at_o stomach_n which_o must_v gradual_o increase_v continual_o how_o come_v opium_n to_o be_v at_o the_o height_n of_o its_o operation_n in_o a_o short_a time_n viz._n in_o about_o half_a a_o hour_n after_o it_o begin_v sensible_o to_o operate_v or_o a_o hour_n at_o far_a and_o not_o increase_v continual_o in_o its_o operation_n as_o their_o pretend_a cause_n the_o fume_n must_v do_v by_o continual_a steam_a 25._o if_o opium_n operate_v by_o send_v fume_n by_o passage_n etc._n etc._n from_o the_o stomach_n to_o the_o brain_n i_o shall_v think_v that_o when_o it_o have_v get_v out_o of_o the_o stomach_n as_o into_o the_o intestine_n lacteal_v vein_n etc._n etc._n there_o shall_v be_v a_o kind_n of_o interval_n of_o its_o operation_n which_o be_v never_o observe_v till_o it_o get_v into_o the_o blood_n again_o therefore_o it_o do_v not_o operate_v by_o fume_n for_o the_o pylorus_n be_v always_o shut_v but_o when_o somewhat_o be_v send_v downward_o which_o will_v hinder_v the_o mount_a of_o the_o vapour_n into_o the_o stomach_n in_o order_n to_o pass_v to_o the_o brain_n 26._o if_o vapour_n be_v the_o cause_n of_o sleep_n after_o meal_n than_o shall_v we_o be_v more_o sleepy_a two_o or_o three_o hour_n after_o meal_n because_o of_o the_o abundance_n of_o the_o fume_n that_o will_v be_v crowd_v into_o the_o brain_n by_o that_o time_n but_o we_o be_v more_o sleepy_a present_o after_o meal_n and_o if_o we_o indulge_v it_o but_o for_o a_o quarter_n of_o a_o hour_n we_o be_v refresh_v and_o far_o from_o sleepiness_n afterward_o though_o the_o fume_n if_o that_o hypothesis_n be_v true_a will_v be_v much_o more_o at_o brain_n two_o or_o three_o hour_n after_o the_o meal_n so_o it_o be_v in_o the_o case_n of_o wine_n if_o one_o take_v a_o short_a nap_n after_o some_o glass_n he_o may_v drink_v a_o great_a many_o afterward_o without_o be_v sleepy_a which_o plain_o prove_v that_o it_o be_v not_o the_o fume_n of_o the_o wine_n be_v the_o cause_n of_o the_o sleep_n because_o he_o be_v not_o at_o all_o sleepy_a when_o there_o must_v be_v more_o fume_n 27._o all_o allow_v that_o hot_a fume_n assault_v the_o brain_n cause_n frenzy_n if_o that_o be_v true_a than_o the_o fume_n of_o wine_n and_o opium_n which_o be_v both_o very_a hot_a must_v always_o do_v so_o but_o opium_n and_o wine_n also_o do_v often_o cause_v composure_n good_a humour_n sleep_v etc._n etc._n which_o be_v contrary_a to_o frenzy_n therefore_o they_o do_v not_o operate_v by_o fume_n 28._o if_o sleep_n say_v helmont_n the_o only_a man_n that_o i_o have_v read_v who_o be_v against_o vapour_n be_v cause_v by_o vapour_n ascend_v from_o the_o stomach_n to_o the_o head_n obstruct_v and_o intercept_n all_o the_o passage_n of_o sensation_n motion_n speech_n judgement_n etc._n etc._n as_o the_o school_n say_v than_o a_o disease_n will_v have_v be_v before_o the_o fall_n of_o adam_n because_o sleep_n will_v have_v be_v a_o disease_n that_o be_v a_o flatulent_a and_o vaporous_a palsy_n 29._o all_o allow_v vomitives_n and_o purger_n to_o operate_v by_o irritation_n or_o a_o grievous_a sensation_n of_o the_o membrane_n of_o the_o stomach_n why_o not_o wine_n cordial_n opium_n etc._n etc._n by_o a_o pleasant_a sensation_n cujus_fw-la est_fw-la dolour_n aut_fw-la gravamen_fw-la ejusdem_fw-la est_fw-la voluptas_fw-la and_o as_o a_o grievous_a sensation_n or_o pain_n cause_v melancholy_a depression_n of_o spirit_n fretfulness_n lassitude_n etc._n etc._n so_o a_o pleasant_a sensation_n cause_v comfort_n elevation_n of_o the_o spirit_n euphory_n etc._n etc._n but_o we_o have_v not_o clear_v the_o way_n sufficient_o for_o these_o matter_n yet_o which_o will_v in_o due_a time_n be_v solemn_o consider_v obj._n it_o may_v be_v say_v that_o both_o vomitives_n and_o purgative_n take_v some_o time_n before_o they_o operate_v unless_o a_o nausea_n upon_o aversion_n cause_v they_o to_o work_v soon_o for_o thing_n must_v have_v time_n to_o insinuate_v themselves_o or_o soak_v through_o the_o crusta_fw-la carnosa_fw-la of_o the_o stomach_n and_o afterward_o to_o affect_v its_o sensile_a coat_n which_o argue_v that_o wine_n and_o cordial_n which_o operate_v immediate_o do_v not_o operate_v that_o way_n but_o by_o fume_n or_o effuvium_n pass_v into_o the_o brain_n or_o blood_n answ._n i_o doubt_v indeed_o that_o this_o difference_n may_v be_v a_o occasion_n of_o refer_v the_o effect_n of_o cordial_n and_o those_o of_o emittick_n and_o cathartic_o to_o different_a cause_n but_o it_o be_v very_o strange_a that_o they_o shall_v go_v so_o far_o as_o the_o blood_n or_o brain_n to_o seek_v for_o the_o cause_n of_o the_o operation_n of_o cordial_n which_o operate_v in_o a_o moment_n and_o go_v no_o far_o than_o the_o stomach_n for_o the_o cause_n of_o the_o operation_n of_o vomatives_n and_o purgative_n which_o take_v more_o time_n to_o operate_v especial_o see_v the_o blood_n and_o brain_n have_v no_o sensation_n and_o that_o all_o sensitive_a comfort_n happen_v by_o that_o mean_n i_o think_v it_o be_v much_o more_o proper_a first_o to_o consider_v the_o immediate_a part_n upon_o which_o they_o insist_v when_o at_o stomach_n especial_o see_v it_o be_v so_o very_o sensible_a before_o we_o run_v rove_a i_o know_v not_o whither_o to_o seek_v for_o the_o cause_n of_o a_o thing_n that_o work_v please_v and_o comfort_v the_o stomach_n as_o soon_o as_o it_o be_v down_o i_o take_v myself_o run_v off_o the_o proper_a subject_a matter_n of_o this_o chapter_n and_o anticipate_v that_o of_o another_o therefore_o i_o will_v be_v short_a and_o deliver_v my_o opinion_n in_o this_o case_n by_o way_n of_o position_n with_o a_o familiar_a instance_n to_o illustrate_v it_o which_o may_v in_o some_o measure_n prepare_v you_o for_o the_o proof_n
of_o man_n because_o of_o its_o ill_a effect_n lavish_o use_v therefore_o none_o can_v argue_v from_o that_o that_o opium_n diminish_v or_o disable_v the_o spirit_n any_o more_o than_o wine_n or_o bread_n do_v a_o surfeit_n of_o which_o be_v most_o dangerous_a omnis_fw-la repletio_fw-la mala_fw-la panis_n vero_fw-la pessima_fw-la &_o corruptio_fw-la optimi_fw-la est_fw-la pessima_fw-la that_o be_v all_o repletion_n be_v bad_a but_o that_o of_o bread_n be_v the_o worst_a and_o the_o corruption_n of_o the_o best_a be_v the_o worst_a the_o short_a be_v this_o wine_n and_o opium_n agree_v in_o all_o their_o effect_n save_v such_o as_o be_v consequence_n of_o their_o different_a accident_n as_o the_o quantity_n of_o wine_n that_o must_v be_v use_v to_o cause_v the_o same_o effect_n with_o a_o little_a opium_n and_o wine_n have_v be_v ferment_v and_o opium_n as_o may_v be_v show_v have_v some_o crude_a and_o viscid_a rosin_n in_o it_o which_o sometime_o stick_v to_o the_o crusta_fw-la carnosa_fw-la etc._n etc._n of_o the_o stomach_n whence_o it_o happen_v that_o wine_n load_v one_o more_o heat_v more_o and_o be_v more_o troublesome_a upon_o those_o account_n and_o that_o opium_n offend_v the_o stomach_n often_o even_o in_o a_o moderate_a do_v cause_v vomit_n hiccough_n anxiety_n distress_n at_o stomach_n deliquium_n etc._n etc._n because_o of_o the_o indigestible_a rosin_n stick_v to_o the_o side_n of_o the_o most_o sensile_a stomach_n as_o i_o shall_v far_o prove_v hereafter_o by_o god_n help_n show_v very_o easy_a way_n and_o mean_n to_o separate_v that_o rosin_n and_o so_o make_v it_o as_o safe_a and_o less_o troublesome_a as_o it_o be_v more_o effectual_a than_o wine_n opium_n can_v diminish_v or_o disable_v the_o spirit_n because_o as_o have_v be_v prove_v it_o send_v no_o part_n fume_v or_o effluvium_fw-la to_o the_o brain_n or_o animal_n spirit_n to_o cause_v such_o bad_a effect_n while_o it_o be_v at_o stomach_n yet_o do_v it_o produce_v they_o while_o it_o be_v there_o for_o as_o the_o vaporarians_n themselves_o and_o indeed_o all_o man_n allow_v there_o can_v be_v no_o destruction_n without_o contact_n sanctorius_n do_v well_o and_o true_o observe_v by_o the_o help_n of_o his_o static_o that_o nothing_o cause_v liberal_a perspiration_n but_o it_o raise_v the_o spirit_n it_o be_v most_o certain_a that_o nothing_o in_o nature_n open_v the_o pore_n and_o cause_n perspiration_n more_o than_o opium_n therefore_o nothing_o shall_v according_a to_o his_o observation_n elevate_v the_o spirit_n more_o and_z indeed_o nothing_o do_v as_o appear_v by_o all_o that_o have_v be_v say_v and_o will_v yet_o more_o plain_o appear_v loss_n of_o memory_n by_o opium_n as_o some_o argue_v be_v not_o so_o much_o a_o loss_n of_o spirit_n as_o lanity_n of_o the_o brain_n for_o people_n in_o drink_n do_v not_o want_v spirit_n but_o there_o be_v a_o great_a relaxation_n of_o the_o brain_n and_o its_o membrane_n and_o of_o the_o whole_a jenus_fw-la 〈◊〉_d which_o relaxation_n cause_v a_o soft_a loose_a and_o labile_fw-la brain_n that_o like_o liquid_a thing_n retain_v no_o impression_n beside_o that_o i_o shall_v god_n will_v show_v you_o hereafter_o that_o impression_n can_v be_v so_o well_o make_v upon_o the_o sensitive_a soul_n by_o the_o animal_n spirit_n upon_o relaxation_n of_o the_o sensible_a part_n as_o in_o sleep_n etc._n etc._n for_o a_o very_a plain_a mechanical_a reason_n to_o be_v show_v in_o due_a time_n thus_o have_v i_o by_o the_o assistance_n of_o its_o maker_n who_o best_o know_v it_o clear_v opium_n from_o the_o false_a aspersion_n of_o a_o extreme_a cold_a quality_n and_o parcotick_a fume_n both_o which_o be_v common_o call_v venomous_a fatal_a and_o by_o all_o the_o ill_a name_n imaginable_a but_o as_o good_a luck_n be_v they_o abuse_v nothing_o because_o it_o be_v manifest_a that_o there_o be_v no_o such_o thing_n nor_o have_v it_o any_o quality_n by_o which_o it_o diminish_v or_o disable_v the_o spirit_n as_o be_v most_o evident_a from_o the_o premise_n so_o that_o all_o that_o have_v be_v say_v of_o opium_n by_o way_n of_o hypothesis_n to_o explain_v its_o effect_n depend_v upon_o its_o diminish_n or_o disable_n the_o spirit_n by_o a_o cold_a quality_n or_o fume_n be_v come_v to_o nothing_o i_o wish_v it_o have_v be_v as_o innocent_a chap._n xii_o show_v what_o must_v be_v the_o true_a cause_n of_o the_o operation_n of_o opium_n all_o the_o general_a foundation_n upon_o which_o author_n either_o ancient_a or_o modern_a erect_v their_o several_a hypothesise_n concern_v the_o operation_n of_o opium_n have_v as_o manifest_o appear_v no_o real_a existence_n what_o enchant_a castle_n in_o the_o air_n or_o vain_a phantasm_n must_v their_o structure_n be_v and_o how_o like_a delude_a wizzard_n must_v they_o appear_v while_o they_o seem_v to_o take_v high_a flight_n and_o glorious_a prospect_n of_o cause_n that_o have_v no_o reality_n thus_o be_o i_o leave_v utter_o destitute_a of_o either_o foundation_n or_o model_n unless_o i_o find_v out_o that_o and_o frame_v this_o which_o i_o hope_v may_v be_v easy_o do_v because_o the_o cloudy_a supposition_n of_o vapour_n have_v vanish_v away_o there_o now_o remain_v but_o two_o way_n by_o which_o a_o internal_a medicament_n can_v operate_v viz._n 1._o as_o a_o alterative_a of_o the_o blood_n etc._n etc._n or_o 2._o as_o affect_v the_o sense_n of_o feel_v either_o grievous_o as_o vomit_n purger_n etc._n etc._n or_o pleas_o as_o cordial_n generous_a wine_n titillate_v amphrodisiack_n comfortable_a warmth_n anodynes_n and_o such_o like_a that_o please_v the_o nerve_n and_o membrane_n which_o way_n of_o operate_n be_v too_o little_o observe_v by_o physician_n though_o they_o take_v great_a notice_n of_o the_o operation_n of_o thing_n by_o grievous_a sensation_n as_o irritative_n to_o vomit_n purge_v salivate_a etc._n etc._n by_o their_o acrimony_n whereas_o the_o pleaser_n of_o sensation_n which_o must_v as_o contrary_n have_v contrary_a operation_n be_v little_o regard_v or_o think_v of_o 1._o opium_n do_v not_o operate_v as_o a_o alterative_a of_o the_o blood_n etc._n etc._n first_o because_o it_o operate_v while_o it_o be_v at_o stomach_n or_o at_o least_o before_o it_o arrive_v at_o the_o blood_n which_o manifest_o appear_v several_a way_n as_o 1._o because_o it_o often_o operate_v in_o a_o liquid_a form_n in_o few_o minute_n and_o very_o common_o in_o a_o quarter_n of_o a_o hour_n in_o which_o time_n it_o must_v be_v at_o stomach_n or_o at_o least_o far_o from_o arrive_v at_o the_o blood_n 2._o because_o it_o have_v be_v very_o often_o vomit_v up_o after_o it_o have_v operate_v and_o produce_v its_o usual_a effect_n for_o 1_o 2_o 3_o 4_o 5_o 6_o 8_o 10_o and_o sometime_o more_o hour_n as_o evident_o appear_v by_o the_o smell_n colour_n taste_v etc._n etc._n of_o what_o be_v vomit_v and_o by_o its_o operation_n cease_v after_o such_o vomit_v of_o which_o common_a experience_n and_o author_n do_v inform_v we_o see_v helmont_n ius_n duumvir_fw-la 62._o where_o he_o tell_v of_o opium_n operate_a at_o night_n and_o vomit_v up_o next_o morning_n 3._o it_o be_v bare_a cause_v vomit_v after_o it_o have_v operate_v for_o a_o good_a while_n be_v of_o itself_o though_o its_o taste_n smell_v etc._n etc._n do_v not_o discover_v it_o a_o infallible_a argument_n of_o its_o operate_n while_o it_o be_v at_o stomach_n for_o it_o be_v against_o all_o reason_n to_o imagine_v that_o thing_n shall_v irritate_fw-la it_o to_o vomit_n after_o they_o be_v go_v into_o the_o blood_n and_o not_o do_v it_o while_o they_o be_v in_o the_o stomach_n itself_o as_o all_o vomitory_n do_v the_o reason_n why_o it_o stay_v so_o long_o at_o stomach_n be_v 1._o it_o be_v indigestibleness_n which_o plain_o appear_v by_o stool_n urine_n and_o sweat_v smell_v of_o it_o when_o take_v in_o any_o considerable_a quantity_n all_o the_o coction_n digestion_n circulation_n etc._n etc._n that_o it_o pass_v in_o the_o body_n signify_v very_o little_a to_o it_o which_o its_o cause_v itch_n in_o the_o skin_n and_o affect_v the_o venereal_a membrane_n after_o its_o pass_v the_o blood_n do_v also_o argue_v 2._o the_o clamminess_n of_o its_o resinous_a part_n stick_v to_o the_o stomach_n cause_n as_o i_o shall_v plain_o prove_v hereafter_o its_o long_a stay_n in_o it_o for_o if_o the_o rosin_n be_v separate_v from_o it_o it_o will_v not_o then_o make_v such_o a_o long_a stay_n at_o stomach_n as_o i_o have_v often_o experience_v 4._o we_o actual_o feel_v it_o cause_v a_o sense_n of_o pleasure_n at_o stomach_n during_o its_o operation_n therefore_o it_o be_v then_o in_o it_o 5._o it_o have_v be_v carry_v off_o by_o stool_n after_o it_o have_v produce_v its_o usual_a effect_n therefore_o it_o operate_v before_o it_o arrive_v at_o the_o blood_n 6._o all_o observer_n do_v allow_v that_o opium_n operate_v while_o it_o be_v at_o stomach_n
which_o give_v the_o occasion_n as_o you_o may_v remember_v to_o the_o hypothesis_n of_o its_o operate_n by_o fume_n rise_v out_o of_o the_o stomach_n because_o they_o can_v not_o think_v of_o any_o other_o mean_v by_o which_o it_o may_v affect_v the_o head_n brain_n animal_n spirit_n nerve_n etc._n etc._n while_o it_o be_v at_o stomach_n but_o by_o the_o way_n of_o fume_n or_o vapour_n it_o be_v therefore_o past_a all_o doubt_n that_o opium_n produce_v its_o common_a effect_n while_o it_o be_v at_o stomach_n and_o before_o it_o arrive_v at_o the_o blood_n and_o therefore_o do_v not_o operate_v as_o a_o alterative_a thereof_o second_o because_o a_o grain_n of_o opium_n which_o operate_v very_o remarkable_o bear_v as_o etmuller_n well_o observe_v so_o small_a a_o proportion_n to_o the_o blood_n that_o it_o can_v produce_v such_o great_a and_o notable_a effect_n as_o a_o alterative_a thereof_o for_o a_o grain_n of_o opium_n to_o 20_o pound_n of_o blood_n which_o a_o ordinary_a man_n have_v in_o his_o body_n be_v but_o as_o 1_o to_o 115200_o or_o if_o 16_o oucne_n be_v allow_v to_o the_o pound_n as_o 1_o to_o 153600._o but_o it_o be_v no_o wonder_n if_o a_o grain_n shall_v affect_v the_o membrane_n at_o stomach_n since_o the_o 1000_o part_n of_o a_o grain_n of_o the_o vomitory_n particle_n of_o crocus_n metallorum_fw-la or_o regulus_n of_o antimony_n do_v affect_v it_o so_o eminent_o as_o many_o other_o thing_n will_v in_o a_o very_a small_a quantity_n whereas_o the_o alter_n of_o the_o blood_n to_o any_o observable_a degree_n require_v the_o use_n of_o alterative_n in_o great_a quantity_n for_o several_a week_n which_o confirm_v the_o former_a conclusion_n that_o opium_n do_v not_o operate_v as_o a_o alterative_a as_o to_o its_o common_a and_o usual_a effect_n ii_o opium_n do_v not_o operate_v by_o grievous_a sensation_n or_o irritation_n as_o vomit_n purger_n errhine_n salivator_n or_o apophlegmatizer_n etc._n etc._n do_v first_o because_o it_o manifest_o cause_v a_o very_a agreeable_a pleasant_a and_o even_o charm_a sensation_n second_o because_o it_o take_v away_o grievous_a sensation_n or_o pain_n thereby_o stop_v vomit_v purge_v and_o all_o other-effect_n of_o grievous_a sensation_n by_o acrimony_n etc._n etc._n as_o for_o the_o vomit_v that_o opium_n sometime_o cause_n it_o be_v only_o as_o shall_v be_v show_v by_o its_o resinous_n part_n stick_v to_o the_o coat_n of_o the_o stomach_n which_o be_v separate_v from_o it_o opium_n have_v no_o such_o effect_n though_o all_o its_o good_a effect_n remain_v so_o its_o purge_v which_o happen_v most_o rare_o and_o only_o when_o a_o great_a quantity_n be_v give_v to_o man_n of_o strong_a digestion_n it_o be_v only_o from_o its_o rosin_n digest_v and_o resolve_v in_o strong_a stomach_n hence_o it_o be_v that_o dog_n and_o such_o as_o have_v canine_a appetite_n do_v general_o purge_v after_o a_o great_a quantity_n of_o crude_a or_o rosinous_n opium_n whereas_o such_o as_o be_v not_o rosinous_n cause_v no_o such_o effect_n but_o of_o these_o matter_n more_o to_o your_o satisfaction_n hereafter_o three_o because_o it_o cause_v all_o effect_n that_o be_v quite_o contrary_a to_o those_o of_o grievous_a sensation_n it_o cause_v a_o ovation_n of_o the_o sensitive_a soul_n and_o spirit_n pain_n or_o grievous_a sensation_n a_o depression_n of_o spirit_n it_o cause_v euphory_n and_o pain_n weariness_n for_o what_o tire_v more_o than_o pain_n or_o labour_v in_o pain_n it_o cause_v good_a humour_n pain_n peevishness_n fretfulness_n and_o ill_a humour_n opium_n cause_v relaxation_n of_o all_o part_n pain_n contraction_n that_o cause_v free_a perspiration_n this_o check_v it_o that_o cause_v sleep_n this_o hinder_v it_o that_o cause_v contentation_n acquiescence_n this_o discontent_n and_o uneasiness_n that_o compose_v this_o discompose_v the_o spirit_n blood_n etc._n etc._n that_o cause_v flux_n by_o irritation_n etc._n etc._n this_o moderate_n or_o stop_v they_o that_o open_v the_o pore_n pain_n constr_v they_o opium_n prevent_v the_o shake_v fit_n in_o ague_n pain_n bring_v they_o on_o that_o cause_v a_o large_a and_o slow_a pulse_n this_o a_o quick_a hard_a and_o narrow_a pulse_n that_o cause_v a_o efflorescence_n of_o the_o skin_n this_o paleness_n that_o pleasant_a this_o unpleasant_a dream_n that_o still_v hiccough_n this_o cause_n they_o that_o take_v off_o contraction_n convulsion_n etc._n etc._n this_o cause_v they_o to_o be_v short_a opium_n cause_v all_o the_o effect_n of_o pleasant_a sensation_n and_o take_v off_o all_o the_o effect_n of_o grievous_a sensation_n what_o can_v be_v a_o more_o evident_a proof_n of_o its_o act_n by_o cause_v a_o pleasant_a sensation_n it_o be_v endless_a to_o mention_v all_o the_o proof_n that_o may_v be_v make_v to_o the_o same_o purpose_n from_o pleaser_n and_o displeaser_n of_o sensation_n therefore_o we_o fair_o conclude_v that_o opium_n do_v not_o operate_v by_o cause_v a_o grievovi_fw-la sensation_n and_o there_o be_v no_o other_o way_n leave_v by_o which_o it_o may_v operate_v it_o must_v operate_v by_o cause_v a_o pleasant_a sensation_n which_o be_v the_o true_a and_o plain_a reason_n why_o as_o have_v be_v show_v it_o take_v off_o pain_n and_o cause_v all_o effect_n quite_o contrary_a to_o that_o of_o grievous_a sensation_n irritation_n by_o acrimony_n etc._n etc._n which_o be_v most_o eminent_a upon_o the_o most_o sensible_a part_n as_o the_o stomach_n intestine_n venereal_a membrane_n skin_n etc._n etc._n as_o you_o may_v observe_v where_o the_o effect_n of_o opium_n be_v enumerate_v now_o gentle_a reader_n consider_v that_o contrary_n be_v the_o true_a cure_n of_o contrary_n what_o can_v then_o cure_v pain_n and_o all_o its_o effect_n better_a than_o pleasure_n it_o be_v very_o strange_a then_o that_o million_o for_o many_o age_n find_v opium_n cure_v or_o take_v off_o pain_n and_o all_o its_o effect_n above_o all_o thing_n shall_v not_o attribute_v its_o so_o do_v to_o its_o cause_v a_o pleasant_a sensation_n which_o be_v the_o direct_a contrary_n to_o pain_n especial_o since_o every_o man_n that_o take_v opium_n feel_v a_o actual_a pleasure_n upon_o take_v thereof_o pleasant_a dream_n a_o pleasant_a humour_n etc._n etc._n it_o may_v be_v say_v what_o if_o it_o be_v grant_v that_o opium_n operate_v by_o a_o please_a sensation_n which_o i_o will_v thank_v none_o for_o that_o have_v feel_v at_o stomach_n or_o reason_n at_o brain_n how_o be_v it_o possible_a that_o such_o pleasant_a sensation_n shall_v cause_v and_o explicate_v all_o the_o various_a strange_a wonderful_a mysterious_a and_o very_o often_o seem_o contradictory_n phenomena_n and_o effect_n of_o opium_n answer_n as_o easy_o as_o ever_o i_o explain_v any_o thing_n in_o nature_n especial_o if_o my_o tract_n of_o animal_n mechanism_n be_v publish_v but_o it_o be_v my_o misfortune_n that_o it_o be_v not_o however_o it_o shall_v not_o be_v the_o reader_n though_o it_o will_v put_v i_o to_o a_o great_a trouble_n to_o evade_v which_o be_v none_o of_o my_o intention_n by_o those_o word_n but_o rather_o to_o bespeak_v the_o reader_n be_v patience_n while_n i_o be_o premise_v some_o necessary_a praecognita_fw-la requisite_a to_o be_v know_v before_o i_o enter_v upon_o the_o explication_n of_o the_o wonderful_a and_o seem_o inexplicable_a effect_n of_o opium_n i_o therefore_o desire_v the_o reader_n be_v leave_v to_o premise_v some_o thing_n of_o the_o nature_n of_o sensation_n and_o sensitive_a pleasure_n in_o order_n to_o his_o more_o clear_a and_o ready_a understanding_n my_o explication_n of_o this_o mysterious_a and_o momentous_a matter_n look_v upon_o as_o so_o dark_a and_o abstruse_a a_o business_n to_o this_o day_n that_o some_o have_v not_o only_o yield_v it_o up_o as_o a_o thing_n hide_v from_o mankind_n but_o have_v earnest_o and_o serious_o argue_v that_o it_o act_v absolute_o by_o a_o occult_a quality_n reserve_v in_o a_o special_a manner_n as_o be_v the_o nature_n of_o spirit_n from_o our_o knowledge_n that_o it_o have_v be_v so_o hitherto_o i_o think_v none_o can_v deny_v as_o the_o circulation_n of_o the_o blood_n be_v for_o thousand_o of_o year_n though_o the_o very_a motion_n be_v see_v by_o million_o so_o as_o the_o cause_n of_o the_o operation_n of_o opium_n have_v be_v feel_v by_o a_o far_o great_a number_n it_o therefore_o will_v if_o i_o fail_v not_o in_o explain_v it_o appear_v so_o clear_a that_o it_o will_v be_v much_o wonder_v at_o like_o that_o of_o the_o circulation_n of_o the_o blood_n why_o so_o obvious_a a_o thing_n be_v not_o find_v by_o every_o one_o that_o use_v opium_n but_o whatever_o opium_n be_v god_n method_n be_v unsearchable_a and_o often_o his_o wise_a providence_n bestow_v good_a gift_n upon_o the_o unworthy_a that_o his_o free_a goodness_n may_v appear_v to_o who_o be_v all_o glory_n praise_n and_o thanksgiving_n for_o ever_o and_o ever_o amen_n note_v that_o while_o i_o be_o upon_o the_o
as_o appear_v by_o several_a place_n or_o passage_n of_o the_o premise_n and_o in_o the_o wake_a more_o than_o in_o such_o as_o be_v asleep_a 6._o it_o be_v manifest_a that_o they_o be_v elastic_a by_o their_o spring_v into_o a_o limb_n hold_v up_o or_o down_o and_o that_o with_o such_o force_n as_o to_o cause_v a_o great_a pain_n after_o they_o have_v be_v exclude_v from_o it_o by_o some_o accident_n as_o lean_v or_o press_v too_o hard_o upon_o a_o nerve_n etc._n etc._n for_o neither_o levity_n nor_o gravity_n can_v do_v so_o especial_o both_o up_o and_o down_o as_o be_v say_v nor_o be_v there_o any_o propulsory_a engine_n for_o they_o as_o be_v for_o the_o blond_n therefore_o it_o must_v be_v from_o their_o springiness_n 7._o they_o can_v not_o cause_v brisk_a and_o smart_a tremulous_a motion_n in_o the_o body_n if_o they_o be_v not_o elastic_a for_o such_o can_v be_v conceive_v by_o any_o mean_n without_o it_o but_o there_o be_v several_a brisk_a and_o smart_a tremulous_a motion_n cause_v by_o the_o animal_n spirit_n as_o in_o the_o shivering_n of_o ague_n fit_n fright_v cold_a surprise_v sudden_a or_o exquisite_a pain_n tremor_n of_o the_o hand_n head_z etc._n etc._n in_o old_a age_n in_o some_o conuâ—_n etc._n etc._n therefore_o the_o animal_n spirit_n that_o cause_v they_o be_v elastic_a 8._o muscle_n have_v no_o springiness_n of_o themselves_o when_o the_o animal_n spirit_n be_v exclude_v from_o they_o as_o in_o palsy_n etc._n etc._n but_o all_o muscle_n in_o their_o exertion_n be_v very_o springy_a insomuch_o that_o if_o you_o hold_v any_o of_o they_o back_o or_o restrain_v they_o from_o their_o motion_n and_o again_o sudden_o leave_v they_o at_o liberty_n during_o the_o exertion_n they_o or_o any_o part_n move_v by_o they_o will_v spring_v out_o very_o violent_o as_o in_o flip_v a_o arm_n hold_v back_o etc._n etc._n but_o nothing_o prove_v this_o matter_n better_o than_o the_o tongue_n in_o form_v the_o sound_n of_o the_o letter_n r_n for_o in_o that_o case_n the_o tongue_n after_o it_o be_v put_v in_o tension_n and_o exertion_n be_v sudden_o hit_v against_o the_o inside_n or_o gum_n of_o the_o upper_a tooth_n do_v thereupon_o as_o springy_a body_n use_v to_o do_v fall_v into_o a_o tremulous_a motion_n or_o jar_a that_o cause_v the_o snarl_a sound_n of_o r_n which_o nothing_o but_o springy_a matter_n can_v do_v 9_o be_v they_o not_o springy_a they_o can_v never_o convey_v the_o tremulous_a motion_n of_o sound_n to_o the_o sensitive_a soul_n and_o indeed_o over_o all_o the_o systeme_n of_o the_o nerve_n by_o which_o be_v cause_v as_o may_v be_v prove_v that_o motion_n of_o consent_n call_v dance_v and_o the_o finger_n etc._n etc._n to_o move_v and_o keep_v time_n with_o the_o music_n even_o when_o it_o or_o the_o finger_n be_v not_o as_o much_o as_o think_v of_o because_o the_o animal_n spirit_n have_v the_o same_o capacity_n with_o the_o air_n to_o receive_v and_o convey_v it_o by_o reason_n of_o their_o springiness_n and_o great_a by_o reason_n of_o their_o more_o forcible_a compression_n by_o the_o vigilative_a contraction_n supper_n add_v to_o the_o compression_n of_o the_o air_n under_o which_o they_o be_v as_o well_o as_o the_o air_n itself_o as_o plain_a reason_n tell_v we_o for_o that_o which_o compress_n the_o whole_a body_n must_v needs_o compress_v the_o animal_n spirit_n the_o experiment_n of_o the_o air-pump_n do_v confirm_v the_o same_o 10._o there_o can_v be_v no_o doubt_n but_o the_o animal_n spirit_n be_v nourish_v or_o sustain_v by_o the_o air_n if_o they_o be_v not_o air_n therefore_o they_o be_v elastic_a what_o need_v any_o more_o argument_n when_o several_a of_o the_o former_a be_v demonstrative_a and_o that_o 11._o all_o physician_n and_o philosopher_n that_o i_o know_v of_o do_v allow_v that_o the_o animal_n spirit_n be_v elastic_a second_o it_o be_v requisite_a as_o be_v say_v of_o the_o external_n medium_fw-la that_o they_o shall_v be_v compress_v to_o render_v they_o fit_a to_o convey_v impression_n and_o that_o they_o be_v compress_v be_v evident_a as_o be_v before_o intimate_v 1._o by_o the_o atmosphere_n 2._o by_o the_o vigilative_a contraction_n which_o make_v they_o much_o more_o dispose_v to_o convey_v impression_n than_o the_o external_n medium_fw-la beside_o that_o very_o often_o two_o other_o contradiction_n that_o be_v show_v in_o the_o remain_a part_n of_o this_o chapter_n be_v add_v thereto_o and_o that_o the_o animal_n spirit_n be_v whole_o contain_v in_o pipe_n to_o prevent_v their_o expansion_n and_o that_o of_o the_o narrow_a size_n that_o can_v well_o be_v imagine_v but_o the_o air_n or_o external_n medium_fw-la be_v at_o large_a in_o the_o atmosphere_n so_o that_o all_o the_o impression_n make_v upon_o the_o animal_n spirit_n be_v very_o tight_o close_o and_o smart_o convey_v nor_o have_v they_o but_o a_o little_a way_n to_o pass_v that_o be_v the_o length_n of_o the_o animal_n at_o most_o which_o also_o may_v be_v some_o advantage_n to_o small_a creature_n but_o in_o sleep_n the_o vigilative_a contraction_n be_v lose_v and_o the_o animal_n spirit_n thereupon_o expanded_a all_o impulse_n must_v needs_o be_v carry_v very_o faint_o both_o because_o the_o organ_n or_o membrane_n be_v indispose_v by_o relaxation_n and_o the_o animal_n spirit_n by_o expansion_n upon_o that_o relaxation_n for_o want_v of_o due_a compression_n to_o fit_v they_o thus_o have_v you_o after_o many_o vain_a inquiry_n the_o true_a mechanical_a cause_n of_o the_o difference_n of_o sensation_n sleep_v and_o wake_v and_o the_o plain_a reason_n why_o our_o motion_n be_v so_o feeble_a in_o sleep_n viz._n because_o the_o animal_n spirit_n have_v lose_v much_o of_o their_o force_n springiness_n etc._n etc._n for_o want_n of_o due_a compression_n by_o reason_n of_o the_o relaxation_n of_o all_o the_o vessel_n that_o include_v the_o spirit_n three_o it_o be_v in_o some_o measure_n requisite_a that_o the_o animal_n spirit_n shall_v have_v a_o homogeneous_a continuity_n as_o be_v show_v by_o the_o analogy_n of_o the_o external_n medium_fw-la which_o do_v not_o convey_v impression_n as_o well_o in_o the_o heat_n of_o the_o day_n as_o in_o the_o night_n or_o after_o sunset_n because_o its_o part_n be_v more_o discontinue_v and_o disgregated_a by_o the_o particle_n of_o heat_n fume_n etc._n etc._n in_o the_o day_n time_n nay_o if_o thing_n be_v discontinue_v they_o never_o carry_v impression_n so_o well_o though_o place_v contiguous_o afterward_o thus_o a_o long_a tree_n that_o convey_v sound_n so_o exact_o from_o one_o end_n to_o the_o other_o while_o all_o be_v continue_v and_o in_o one_o piece_n will_v not_o convey_v the_o sound_n so_o well_o if_o it_o be_v cut_v into_o many_o piece_n though_o they_o be_v afterward_o put_v close_o one_o to_o the_o other_o as_o to_o this_o matter_n of_o continuity_n in_o the_o animal_n spirit_n see_v it_o do_v not_o much_o concern_v we_o and_o that_o people_n in_o a_o state_n of_o health_n be_v suppose_v to_o have_v it_o and_o that_o it_o be_v not_o our_o business_n here_o to_o enter_v upon_o the_o consideration_n of_o nervous_a distemper_n i_o need_v not_o use_v any_o more_o word_n about_o it_o but_o that_o if_o it_o any_o way_n happen_v to_o be_v discontinue_v as_o either_o by_o the_o penury_n thereof_o that_o they_o do_v not_o quite_o fill_v all_o part_n of_o their_o vessel_n or_o any_o matter_n intercept_n their_o part_n or_o that_o the_o vessel_n shall_v be_v so_o relax_v or_o widen_v that_o the_o animal_n spirit_n can_v so_o well_o fill_v they_o up_o etc._n etc._n such_o cause_n must_v destroy_v or_o lessen_v sensation_n though_o the_o bare_a mix_n of_o fume_n with_o they_o will_v not_o consider_v the_o shortness_n of_o the_o way_n that_o impression_n be_v carry_v in_o animal_n much_o alter_v the_o case_n as_o you_o find_v fume_n in_o the_o air_n do_v not_o much_o hinder_a sound_n at_o the_o distance_n of_o a_o yard_n or_o two_o wherein_o it_o be_v insensible_a to_o common_a observer_n at_o least_o so_o that_o if_o some_o fume_n from_o a_o grain_n or_o two_o of_o opium_n do_v mingle_v with_o the_o animal_n spirit_n it_o will_v not_o cause_v a_o sensible_a difference_n of_o feel_v in_o the_o short_a space_n of_o the_o length_n of_o a_o animal_n but_o i_o have_v prove_v that_o no_o such_o fume_v from_o the_o opium_n mix_v with_o they_o therefore_o need_v say_v no_o more_o of_o this_o matter_n v._o the_o office_n or_o business_n of_o the_o sensitive_a soul_n in_o the_o oeconomy_n of_o sensation_n be_v to_o perceive_v the_o impression_n convey_v to_o he_o by_o the_o animal_n spirit_n that_o he_o may_v if_o he_o find_v they_o disagreeable_a bestir_v himself_o in_o defence_n of_o the_o animal_n first_o it_o be_v requisite_a he_o shall_v attend_v to_o all_o impression_n offer_v he_o by_o the_o animal_n spirit_n otherwise_o
impression_n of_o great_a concernment_n may_v escape_v his_o notice_n and_o consequent_o want_v his_o assistance_n by_o way_n of_o defence_n for_o it_o be_v manifest_a that_o when_o his_o attention_n be_v divert_v by_o any_o object_n more_o especial_o by_o such_o as_o mighty_o please_v he_o as_o in_o the_o act_n of_o venery_n and_o other_o pleasure_n especial_o if_o intense_a that_o he_o do_v not_o perceive_v other_o object_n at_o the_o time_n that_o he_o be_v so_o divert_v and_o if_o the_o pleasant_a diversion_n be_v intense_a and_o permanent_a as_o in_o the_o case_n of_o opium_n and_o wine_n drink_v in_o a_o considerable_a quantity_n he_o be_v so_o take_v up_o divert_v or_o charm_v therewith_o that_o he_o do_v not_o attend_v to_o the_o business_n of_o sensation_n this_o be_v one_o reason_n why_o such_o as_o be_v far_o go_v in_o drink_n have_v none_o of_o their_o sense_n aright_o but_o as_o to_o the_o illustration_n of_o this_o matter_n you_o may_v expect_v more_o hereafter_o note_v that_o the_o sensitive_a soul_n be_v the_o only_a thing_n iâ—_n a_o animal_n that_o have_v perception_n and_o therefore_o the_o only_a thing_n that_o be_v sensible_a of_o any_o grievance_n weariness_n hunger_n pleasure_n comfort_n etc._n etc._n second_o it_o be_v requisite_a that_o it_o shall_v use_v all_o mean_n that_o be_v in_o its_o power_n that_o the_o impression_n shall_v be_v bring_v to_o it_o very_o entire_o exact_o smart_o etc._n etc._n so_o as_o to_o have_v due_a notice_n of_o all_o object_n and_o the_o small_a impression_n that_o may_v be_v for_o which_o good_a end_n and_o purpose_v god_n have_v endue_v the_o sensitive_a soul_n as_o will_v be_v full_o prove_v with_o a_o power_n of_o contract_v all_o the_o sensile_n small_a and_o slender_a pipe_n vessel_n or_o passage_n of_o the_o animal_n spirit_n for_o the_o more_o express_a distinct_a and_o accurate_a conveyance_n of_o all_o impression_n by_o the_o help_n of_o compression_n therefore_o the_o sensitive_a soul_n take_v the_o advantage_n thereof_o for_o better_a information_n in_o order_n to_o self-preservation_n do_v by_o the_o appointment_n of_o the_o preserver_n of_o all_o thing_n execute_v his_o power_n by_o the_o aforementioned_a vigilative_a contraction_n of_o those_o part_n to_o cause_v their_o tension_n and_o great_a compression_n of_o the_o animal_n spirit_n to_o improve_v the_o impression_n that_o be_v to_o be_v convey_v to_o he_o and_o render_v they_o more_o observable_a this_o god_n who_o have_v make_v nothing_o to_o be_v idle_a and_o particular_o order_v the_o sensitive_a soul_n in_o adam_n for_o labour_n especeal_o in_o reference_n to_o their_o own_o safety_n and_o preservation_n have_v make_v to_o be_v the_o ordinary_a employ_v or_o day-work_a of_o the_o sensitive_a soul_n that_o by_o the_o say_v vigilative_a contraction_n the_o organ_n membrane_n vessel_n etc._n etc._n may_v be_v render_v more_o tense_n and_o firm_a and_o the_o animal_n spirit_n more_o compress_v springy_a prompt_a flippant_a and_o forcible_a for_o the_o benefit_n of_o sense_n and_o motion_n upon_o all_o occasion_n of_o defence_n flight_n struggle_v etc._n etc._n which_o be_v our_o state_n of_o vigilancy_n as_o have_v be_v intimate_v but_o the_o keep_n of_o the_o say_a part_n membrane_n etc._n etc._n in_o continual_a contraction_n even_o against_o the_o renitency_n of_o the_o elastic_a spirit_n which_o resist_v and_o thrust_v the_o hard_a against_o their_o vessel_n by_o how_o much_o the_o more_o they_o compress_v they_o by_o the_o vigilative_a contraction_n be_v a_o continual_a tedious_a labour_n and_o fatigue_n of_o which_o the_o sensitive_a soul_n be_v sensible_a as_o the_o only_a perceiver_n of_o lassitude_n or_o indeed_o of_o any_o thing_n beside_o in_o a_o animal_n and_o in_o his_o nature_n but_o material_a changeable_a fatigable_a frail_a subject_a to_o be_v wear_v out_o and_o capable_a of_o decay_n which_o make_v the_o certainty_n of_o death_n in_o all_o animal_n and_o in_o we_o since_o the_o fall_n into_o a_o animal_n nature_n do_v upon_o that_o account_n and_o lest_o the_o continual_a contraction_n and_o tensive_a stress_n of_o part_n by_o that_o mean_n shall_v spoil_v their_o tone_n and_o to_o recruit_v the_o waste_a spirit_n by_o rest_n after_o tuggingall_a day_n at_o the_o vigilative_a contraction_n grow_v willing_a to_o give_v over_o the_o drudgery_n however_o convenient_a for_o the_o use_v aforesaid_a therefore_o be_v allow_v convenient_a rest_n by_o his_o maker_n he_o for_o the_o great_a benefit_n of_o refection_n without_o which_o he_o can_v continue_v his_o be_v and_o for_o the_o sweetness_n of_o ease_n loosen_v the_o reins_o of_o vigilative_a contraction_n whereupon_o sensation_n and_o promptitude_n to_o motion_n which_o be_v maintain_v by_o that_o contraction_n cause_v the_o tension_n of_o organ_n and_o compression_n of_o the_o animal_n spirit_n as_o have_v be_v mechanical_o demonstrate_v fail_v by_o the_o relaxation_n of_o those_o organ_n membrane_n and_o vessel_n of_o the_o spirit_n and_o the_o consequent_a expansion_n of_o the_o animal_n spirit_n so_o that_o now_o only_a the_o compression_n of_o the_o atmosphere_n remain_v which_o as_o you_o see_v in_o a_o gut_n half_n full_a of_o air_n under_o that_o pressure_n be_v not_o sufficient_a to_o convey_v the_o impression_n with_o any_o smartness_n or_o cause_v the_o animal_n spirit_n to_o spring_v vigorous_o into_o motion_n which_o decay_n or_o failure_n of_o sense_n and_o motion_n by_o relaxation_n and_o the_o consequent_a expansion_n of_o the_o animal_n spirit_n be_v the_o state_n of_o natural_a sleep_n note_v that_o relaxation_n be_v a_o necessary_a consequence_n of_o the_o privation_n of_o contraction_n and_o require_v no_o labour_n but_o a_o bare_a remission_n of_o that_o contraction_n note_v that_o the_o watch_a part_n of_o our_o life_n be_v uphold_v by_o force_n and_o that_o nullum_fw-la violentum_fw-la est_fw-la diuturnum_fw-la and_o consequent_o a_o necessity_n of_o sleep_n and_o at_o last_o of_o death_n itself_o thus_o have_v you_o the_o true_a reason_n of_o sleep_v and_o watch_v which_o will_v natural_o plain_o and_o easy_o solve_v all_o the_o phenomena_n thereof_o for_o it_o be_v most_o evident_a from_o the_o premise_n 1._o why_o watch_v and_o sleep_v observe_v a_o proportion_n between_o they_o the_o be_v tire_v with_o one_o be_v the_o cause_n of_o the_o other_o 2._o why_o sense_n and_o motion_n do_v fail_v so_o much_o in_o sleep_n viz._n by_o the_o relaxation_n of_o all_o part_n and_o expansion_n of_o the_o animal_n spirit_n 3._o why_o they_o always_o fail_v together_o and_o in_o like_a proportion_n 4._o why_o they_o do_v not_o whole_o fail_v in_o sleep_n because_o the_o compressure_n of_o the_o atmosphere_n etc._n etc._n remain_v 5._o why_o in_o sleep_v the_o limb_n be_v like_o a_o gut_n half_n full_a of_o air_n lax_n limber_a flaccid_a and_o yield_v all_o manner_n of_o way_n because_o all_o the_o innumerable_a small_a vessel_n that_o contain_v the_o elastic_a animal_n spirit_n be_v as_o that_o half_a fill_v gut_n i_o mention_v not_o tight_o fill_v which_o if_o they_o be_v will_v be_v firm_a and_o tense_n as_o such_o a_o gut_n blow_v up_o very_o full_a and_o forcible_o be_v which_o vessel_n be_v all_o over_o the_o body_n confirm_v the_o whole_a tone_n when_o we_o be_v awake_a and_o the_o vigilative_a contraction_n compress_n the_o animal_n spirit_n into_o a_o steadiness_n and_o as_o it_o be_v a_o kind_a of_o solidity_n 6._o why_o as_o appear_v by_o statick_a demonstration_n and_o experiment_n we_o perspire_v more_o when_o asleep_a than_o awake_a because_o the_o pore_n be_v close_v by_o the_o vigilative_a contraction_n and_o open_v in_o sleep_n by_o the_o contrary_a relaxation_n which_o therefore_o always_o cause_v free_a perspiration_n where_o ever_o it_o happen_v as_o in_o faint_a fit_n syncopes_fw-la leipothymy_n and_o by_o warmth_n especial_o if_o moist_a and_o emollient_a as_o in_o bath_n fomentation_n foot_n wash_v head_n wash_v etc._n etc._n as_o also_o when_o pleasure_n relax_n as_o in_o the_o act_n of_o venery_n great_a joy_n after_o good_a meal_n or_o some_o glass_n of_o wine_n etc._n etc._n all_o which_o cause_n plentiful_a perspiration_n because_o they_o relax_v and_o thereby_o open_a the_o pore_n as_o more_o full_o appear_v in_o the_o follow_a discourse_n by_o reason_n of_o the_o pleasure_n that_o they_o cause_n which_o divert_v the_o sensitive_a soul_n from_o his_o employ_v of_o contraction_n 7._o why_o the_o pore_n be_v open_a by_o the_o relaxation_n we_o sweat_v in_o our_o sleep_n if_o we_o be_v fill_v with_o matter_n for_o it_o viz._n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o be_v much_o sweat_v in_o sleep_n argue_v that_o much_o food_n or_o nutriment_n be_v take_v of_o which_o drink_n be_v the_o great_a part_n in_o bulk_n even_o in_o sober_a person_n i_o mention_v this_o to_o show_v the_o difference_n in_o the_o case_n of_o perspiration_n and_o sweat_v for_o that_o always_o happen_v in_o sleep_n but_o not_o sweat_v unless_o
sensation_n of_o the_o sensile_a part_n which_o can_v well_o happen_v in_o that_o sound_a sleep_n wherein_o there_o be_v so_o little_a feel_v by_o reason_n of_o the_o say_a relaxation_n and_o because_o relaxation_n oppose_v contraction_n by_o which_o that_o shiver_a be_v promote_v such_o a_o relaxation_n and_o failure_n of_o feel_v thereupon_o be_v the_o true_a cause_n why_o opium_n put_v off_o ague_n fit_n etc._n etc._n so_o 20._o the_o relaxation_n in_o sleep_n stop_v vomit_v by_o take_v away_o the_o sense_n of_o the_o irritate_v cause_n and_o quiet_v as_o i_o have_v intimate_v all_o motion_n in_o general_a so_o sleep_v stop_n hiccough_n hemorrhage_n diary_n fever_n etc._n etc._n 21._o why_o watch_v labour_n or_o what_o impair_v the_o spirit_n and_o tire_v the_o sensitive_a soul_n incline_v we_o to_o sleep_v that_o be_v dispose_v the_o sensitive_a soul_n the_o only_a feeler_n of_o lassitude_n to_o give_v over_o contract_n the_o sensile_a part_n which_o as_o will_v plain_o appear_v by_o and_o by_o spend_v the_o spirit_n as_o sleep_v by_o relax_v they_o cause_v a_o recruit_v thereof_o to_o be_v short_a though_o one_o can_v hardly_o be_v too_o long_o in_o solve_v phenomena_n which_o be_v the_o proof_n of_o the_o truth_n of_o a_o man_n assertion_n the_o mechanical_a demonstration_n that_o i_o have_v make_v of_o the_o state_n of_o sleep_v and_o wake_v do_v so_o evident_o explicate_v all_o the_o phenomena_n of_o both_o that_o i_o be_o even_o ashamed_a to_o run_v any_o far_o upon_o such_o plain_a matter_n so_o obvious_a be_v thing_n when_o the_o truth_n be_v know_v and_o therefore_o have_v mention_v those_o circumstance_n and_o effect_n of_o sleep_n that_o main_o concern_v we_o i_o must_v give_v over_o lest_o the_o world_n shall_v think_v that_o i_o take_v all_o my_o reader_n to_o be_v idiot_n by_o use_v too_o many_o word_n in_o so_o obvious_a a_o thing_n or_o that_o i_o be_o no_o better_o for_o use_v they_o without_o cause_n for_o the_o truth_n of_o this_o matter_n seem_v to_o i_o to_o outshine_v all_o the_o argument_n i_o can_v make_v for_o it_o such_o splendour_n do_v truth_n show_v upon_o the_o first_o glimpse_n thereof_o as_o i_o take_v the_o account_n i_o give_v of_o sleep_n and_o watch_v to_o be_v for_o the_o opinion_n i_o have_v meet_v concern_v they_o be_v quite_o contrary_a to_o or_o very_o remote_a from_o what_o i_o have_v state_v 1._o they_o go_v quite_o contrary_a to_o it_o that_o say_v that_o the_o animal_n spirit_n be_v expanded_a and_o the_o pore_n of_o the_o brain_n etc._n etc._n more_o open_a and_o consequent_o more_o lax_n in_o watch_v as_o willis_n and_o several_a other_o who_o therefore_o say_v that_o coffee_n volatile_a salt_n etc._n etc._n be_v antihypnotick_n or_o good_a against_o too_o much_o sleepiness_n because_o they_o cause_v a_o expansion_n of_o the_o spirit_n and_o open_v the_o pore_n of_o the_o brain_n suppose_v forsooth_o that_o they_o march_v up_o and_o down_o and_o so_o keep_v the_o great_a stir_n upon_o the_o false_a imagination_n of_o their_o road_n be_v more_o open_a which_o as_o be_v prove_v be_v real_o more_o close_a coffee_n keep_v we_o from_o sleep_n by_o dry_v bind_a and_o both_o way_n constr_v the_o vessel_n as_o also_o by_o a_o wide_a grate_a quality_n which_o therefore_o do_v irritate_fw-la they_o to_o contract_v beside_o that_o the_o saline_n particle_n cause_v a_o agitation_n may_v contribute_v thereto_o so_o that_o by_o constr_v and_o agitate_v it_o direct_o oppose_v sleep_n which_o proceed_v from_o relaxation_n and_o quietness_n 2._o they_o be_v very_o remote_a from_o the_o mark_n that_o say_v as_o wedeliâ—s_a assert_n all_o do_v that_o vapour_n be_v the_o cause_n of_o natural_a sleep_n which_o bear_v no_o manner_n of_o proportion_n thereto_o as_o be_v show_v as_o they_o be_v also_o who_o mâ—dly_o talk_v that_o the_o animal_n spirit_n which_o have_v neither_o life_n sense_n motion_n or_o election_n do_v of_o themselves_o retire_v very_o know_o to_o the_o brain_n in_o sâ—eep_n and_o leave_v the_o limb_n etc._n etc._n destitute_a of_o they_o whereas_o as_o have_v be_v mechanical_o prove_v they_o have_v more_o room_n than_o that_o at_o other_o time_n in_o 〈◊〉_d limb_n and_o all_o the_o sensile_a part_n but_o i_o will_v not_o argue_v against_o such_o senseless_a and_o precarious_a absurdity_n it_o be_v not_o worth_a the_o while_n especial_o since_o the_o truth_n be_v manifest_o discover_v it_o will_v not_o have_v be_v so_o silly_a to_o have_v affirm_v the_o quite_o contrary_a viz._n that_o the_o animal_n spirit_n be_v force_v into_o the_o soft_a and_o yield_a brain_n in_o watch_v by_o the_o vigilative_a contraction_n of_o all_o the_o senfile_v part_n repel_v they_o as_o when_o cold_a repel_v they_o by_o a_o strong_a contraction_n of_o the_o part_n and_o cause_v a_o stupor_n or_o sleep_n thereof_o as_o they_o call_v it_o but_o what_o have_v we_o to_o do_v with_o such_o insufferable_a trash_n therefore_o bid_v it_o adieu_n let_v we_o pursue_v our_o business_n that_o it_o be_v the_o sensitive_a soul_n and_o nothing_o but_o it_o have_v that_o contract_n power_n be_v evident_a 1._o because_o it_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n as_o such_o and_o that_o nothing_o beside_o it_o have_v any_o life_n perception_n motion_n or_o power_n and_o therefore_o must_v rest_v till_o they_o be_v move_v 2._o because_o that_o when_o the_o sensitive_a soul_n be_v divert_v by_o intense_a pleasure_n from_o attend_v his_o business_n immediate_o relaxation_n follow_v as_o in_o the_o pleasure_n of_o the_o act_n of_o venery_n by_o wine_n joy_n etc._n etc._n in_o which_o you_o have_v all_o the_o effect_n of_o relaxation_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la plentiful_a perspiration_n floridity_n of_o the_o skin_n a_o large_a pulse_n and_o sometime_o a_o considerable_a failure_n of_o sense_n and_o motion_n as_o in_o the_o most_o pleasant_a time_n of_o the_o venereal_a act_n deliquiums_n drunkenness_n syncopes_fw-la or_o ecstasy_n upon_o intense_a pleasure_n which_o be_v very_o proper_o call_v ecstasy_n leipothymy_n leipopsychy_n etc._n etc._n which_o signify_v the_o soul_n leave_v we_o without_o his_o help_n by_o contraction_n which_o he_o then_o do_v not_o exercise_n as_o be_v charm_v and_o whole_o take_v up_o with_o pleasure_n this_o be_v the_o true_a cause_n of_o all_o deliquium_n etc._n etc._n upon_o pleasure_n joy_n etc._n etc._n all_o which_o cause_n great_a relaxation_n and_o thereby_o loss_n of_o sense_n and_o motion_n as_o be_v its_o necessary_a consequence_n 3._o because_o grievous_a sensation_n which_o belong_v only_o to_o the_o sensitive_a soul_n put_v we_o immediate_o out_o of_o sleep_n into_o a_o vigilative_a contraction_n 4._o because_o the_o sensitive_a soul_n can_v when_o we_o be_v sleepy_a oppose_v it_o by_o continue_v the_o vigilative_a contraction_n which_o prove_v vigilative_a contraction_n to_o be_v in_o his_o power_n note_v that_o there_o be_v also_o other_o sort_n of_o leipothymy_n deliquium_n etc._n etc._n upon_o the_o sensitive_a soul_n be_v overtired_n whereof_o natural_a sleep_n be_v but_o a_o common_a and_o ordinary_a degree_n that_o happen_v of_o course_n for_o our_o relief_n or_o overbear_v with_o some_o fatigue_n etc._n etc._n as_o when_o somewhat_o grieve_v at_o stomach_n and_o that_o it_o have_v lay_v about_o it_o all_o manner_n of_o way_n by_o vomit_v convulsive_a motion_n etc._n etc._n to_o be_v rid_v of_o it_o till_o it_o can_v work_v no_o long_o whereupon_o it_o lay_v down_o the_o cudgel_n desi_v from_o all_o further_a endeavour_n by_o contraction_n yield_v itself_o to_o ease_n see_v all_o strive_v be_v to_o no_o effect_n so_o that_o though_o this_o deliquium_fw-la and_o the_o former_a differ_v in_o their_o first_o cause_n yet_o do_v they_o agree_v in_o the_o last_o and_o immediate_a viz._n the_o sensitive_a soul_n be_v not_o attend_v his_o business_n of_o contraction_n whereupon_o follow_v a_o mighty_a relaxation_n as_o appear_v by_o the_o deadness_n or_o relaxation_n of_o the_o cornea_n dilatation_n of_o the_o pupil_n a_o great_a laxity_n of_o all_o part_n a_o large_a pulse_n or_o none_o very_o plentiful_a perspiration_n stop_v of_o hemorrhage_n and_o all_o flux_n that_o require_v contraction_n etc._n etc._n which_o happen_v both_o upon_o the_o account_n of_o the_o great_a relaxation_n itself_o as_o have_v be_v show_v and_o the_o almost_o absolute_a rest_n of_o all_o thing_n by_o the_o sensitive_a soul_n withdraw_a himself_n from_o business_n more_o than_o in_o sleep_n itself_o i_o therefore_o observe_v the_o degree_n of_o sleep_n etc._n etc._n do_v note_n that_o god_n and_o nature_n use_v a_o due_a proportion_n in_o all_o thing_n the_o sensitive_a soul_n use_v several_a degree_n of_o relaxation_n according_a as_o he_o be_v tire_v and_o refection_n be_v want_v hence_o it_o be_v that_o such_o as_o be_v much_o tire_v sleep_n more_o profound_o that_o our_o first_o
which_o have_v be_v in_o some_o measure_n enumerate_v in_o the_o case_n of_o natural_a sleep_n in_o this_o chapter_n viz._n satisfaction_n composure_n of_o fret_n and_o commotion_n as_o of_o diary_n fever_n hysterick_a fit_n etc._n etc._n perspiration_n quiet_v of_o vomit_n hiccough_n etc._n etc._n lessen_v of_o feel_v and_o consequent_o a_o stop_n and_o moderation_n of_o all_o flux_n that_o depend_v upon_o irritation_n of_o humour_n as_o diarrhea_n dysentery_n catarrh_n vomit_n dryness_n of_o the_o mouth_n as_o in_o sleep_n for_o want_v of_o the_o contraction_n to_o squeeze_v the_o spital_n out_o of_o the_o glandule_n into_o the_o mouth_n nocturnal_a pollution_n etc._n etc._n but_o of_o the_o nature_n and_o effect_n of_o pleasure_n you_o will_v find_v more_o in_o the_o next_o chapter_n beside_o the_o vigilative_a and_o defensive_a contraction_n which_o seem_v to_o be_v thing_n of_o course_n upon_o wake_v and_o grievance_n the_o sensitive_a soul_n have_v a_o contraction_n at_o will_n as_o that_o of_o the_o pupilla_fw-la when_o a_o animal_n be_v intent_n upon_o see_v of_o the_o tympan_n when_o intent_n upon_o hear_v of_o the_o musole_n of_o the_o leg_n when_o intent_n upon_o walk_v and_o so_o of_o all_o the_o muscle_n of_o the_o body_n which_o i_o call_v intentive_a contraction_n that_o he_o can_v perform_v either_o along_o with_o or_o without_o the_o other_o contraction_n or_o without_o any_o great_a degree_n thereof_o as_o when_o one_o be_v considerable_o relax_v with_o the_o pleasure_n of_o wine_n very_o good_a news_n etc._n etc._n nay_o sometime_o even_o in_o sleep_n as_o be_v manifest_a by_o the_o noctamâ—uli_n or_o such_o as_o walk_v in_o their_o sleep_n and_o such_o as_o speak_v strike_v etc._n etc._n while_o asleep_a and_o as_o the_o defensive_a contraction_n do_v all_o it_o can_v in_o our_o defence_n without_o the_o direction_n of_o the_o will_n as_o in_o vomit_v sneeze_n purge_v etc._n etc._n upon_o sensible_a irritation_n so_o this_o intentive_a contraction_n do_v all_o it_o can_v to_o the_o same_o purpose_n by_o the_o direction_n and_o dictate_v thereof_o note_v that_o insensile_a grow_a thing_n that_o do_v not_o move_v as_o tree_n etc._n etc._n have_v none_o of_o these_o contraction_n but_o what_o happen_v by_o cold_a and_o compression_n of_o the_o atmosphere_n which_o be_v sufficient_a it_o seem_v for_o nutrition_n but_o not_o for_o sense_n and_o motion_n it_o follow_v that_o in_o complete_a syncopes_fw-la when_o the_o sensitive_a soul_n give_v over_o all_o contraction_n that_o we_o be_v much_o in_o the_o state_n of_o a_o plant._n all_o those_o three_o contraction_n viz._n the_o vigilative_a defensive_a and_o intentive_a do_v because_o they_o promote_v motion_n and_o cause_v it_o more_o or_o less_o as_o you_o find_v the_o vigilative_a cause_n much_o more_o of_o it_o than_o sleep_v and_o the_o defensive_a more_o than_o that_o etc._n etc._n spend_v the_o spirit_n cause_n weariness_n etc._n etc._n the_o vigilative_a contraction_n do_v of_o itself_o without_o any_o considerable_a grievance_n or_o labour_n that_o be_v without_o the_o denfensive_a or_o intentive_a contraction_n tire_v the_o sensitive_a soul_n in_o about_o 16_o hour_n hence_o it_o be_v that_o the_o idle_v person_n that_o be_v most_o free_a from_o care_n trouble_v or_o pain_n can_v well_o hold_v out_o without_o the_o recruit_v of_o sleep_n any_o long_o the_o defensive_a contraction_n or_o that_o of_o grievance_n be_v add_v to_o the_o vigilative_a contraction_n the_o spirit_n be_v fast_o spend_v and_o the_o person_n tire_v proportionable_o soon_o according_a as_o the_o grievance_n be_v more_o or_o less_o and_o consequent_o the_o endeavour_n of_o the_o sensitive_a soul_n to_o be_v rid_v thereof_o to_o both_o which_o contraction_n viz._n the_o vigilative_a and_o defensive_a if_o you_o add_v the_o intentive_a or_o labour_n then_o be_v you_o soon_o and_o more_o tire_v than_o by_o only_a those_o two_o former_a contraction_n for_o this_o last_o case_n be_v labour_v in_o pain_n or_o under_o a_o grievance_n which_o notorious_o tire_v man_n or_o beast_n soon_o than_o ordinary_a the_o direct_a contrary_n to_o which_o be_v sleep_v sound_o and_o sweet_o without_o trouble_n pain_n or_o dream_n for_o a_o dream_a condition_n have_v too_o much_o of_o the_o vigilative_a contraction_n in_o it_o to_o be_v pure_a relaxation_n and_o recruit_v now_o according_a as_o these_o contraction_n be_v or_o be_v not_o add_v one_o to_o another_o we_o be_v soon_o or_o late_a before_o we_o be_v tire_v speak_v general_o and_o not_o consider_v custom_n and_o habit_n which_o concern_v we_o not_o you_o see_v that_o all_o the_o three_o contraction_n conour_v do_v soon_o and_o sad_o tire_v we_o that_o no_o two_o of_o they_o tire_v we_o as_o much_o as_o the_o three_o together_o that_o iâ—_n neither_o the_o vigilative_a and_o defensive_a without_o the_o intentive_a nor_o the_o vigilative_a and_o intentive_a without_o the_o defensive_a and_o the_o vigilative_a alone_o lest_o of_o all_o yet_o allowance_n must_v be_v make_v for_o the_o intenseness_n of_o the_o defensive_a and_o intentive_a for_o either_o of_o these_o two_o be_v very_a intense_a may_v tire_v as_o much_o as_o both_o in_o a_o moderate_a degree_n thus_o a_o man_n may_v be_v tire_v with_o violent_a labour_n in_o four_o hour_n though_o not_o in_o pain_n as_o much_o as_o one_o that_o moderate_o labour_v in_o some_o small_a pain_n for_o the_o same_o time_n observe_v that_o we_o recruit_v in_o eight_o hour_n general_o speak_v as_o much_o by_o relaxation_n in_o sleep_n as_o we_o spend_v by_o vigilative_a contraction_n in_o sixteen_o i_o take_v the_o reason_n of_o that_o to_o be_v that_o relaxation_n widen_v all_o the_o passage_n of_o the_o body_n the_o nutriment_n be_v admit_v into_o they_o more_o full_o and_o free_o as_o the_o blood_n be_v into_o the_o skin_n in_o sleep_n and_o all_o relaxation_n which_o cause_n a_o efflorescence_n thereof_o in_o those_o case_n hence_o it_o be_v that_o we_o be_v so_o much_o recruit_v and_o nourish_v in_o sleep_n that_o child_n grow_v more_o than_o other_o proportionable_o that_o relaxer_n cause_v the_o breast_n etc._n etc._n to_o grow_v note_v what_o a_o mighty_a restaurative_a relaxation_n be_v by_o its_o help_n for_o eight_o hour_n in_o twenty_o four_o we_o can_v watch_v all_o and_o labour_v most_o of_o the_o other_o sixteen_o all_o the_o day_n of_o our_o life_n it_o follow_v that_o if_o we_o can_v any_o way_n half_o relax_v the_o vigilative_a contraction_n while_o we_o labour_v take_v a_o journey_n or_o the_o like_a that_o we_o may_v perform_v prodigious_o without_o be_v â—ired_v hence_o it_o be_v that_o because_o pleasure_n as_o have_v be_v intimate_v relax_n as_o grievance_n contract_v of_o which_o you_o may_v expect_v far_a proof_n in_o the_o next_o chapter_n that_o such_o as_o work_v or_o travel_n pleasant_o divert_v all_o the_o time_n be_v tire_v very_o little_a or_o nothing_o in_o a_o long_a time_n and_o that_o some_o will_v dance_v whole_a nightâ—_n with_o sweet_a music_n and_o agreeable_a belove_a company_n without_o be_v so_o much_o tire_v as_o they_o will_v be_v if_o they_o use_v the_o same_o motion_n for_o a_o quarter_n of_o the_o time_n without_o either_o of_o the_o pleasant_a diversion_n the_o like_a be_v to_o be_v say_v of_o any_o other_o pleasure_n as_o drink_v a_o good_a glass_n of_o generous_a wine_n every_o half_a hour_n or_o so_o often_o as_o to_o continue_v the_o sense_n of_o its_o pleasure_n at_o stomach_n all_o the_o time_n they_o labour_v or_o travel_v for_o it_o be_v a_o vulgar_a error_n though_o the_o universal_a sentiment_n of_o mankind_n both_o learned_a and_o unlearned_a that_o wine_n cordial_n etc._n etc._n do_v comfort_n elevate_v and_o excite_v the_o spirit_n as_o it_o be_v call_v by_o add_v their_o spirit_n to_o or_o join_v they_o with_o we_o whereas_o it_o be_v only_o by_o cause_v a_o pleasant_a sensation_n particular_o at_o stomach_n for_o which_o paradox_n i_o be_o oblige_v though_o in_o great_a haste_n to_o come_v to_o the_o explication_n of_o opium_n to_o give_v my_o reason_n which_o be_v as_o follow_v viz._n 1._o it_o can_v be_v imagine_v how_o a_o sensitive_a creature_n as_o such_o can_v conceive_v any_o comfort_n or_o be_v sensible_a thereof_o but_o by_o sensation_n to_o say_v he_o be_v comfort_v and_o not_o sensible_a of_o the_o comfort_n be_v a_o contradiction_n for_o comfort_n as_o such_o belong_v to_o a_o perceive_v be_v and_o a_o animal_n as_o such_o perceive_v nothing_o but_o by_o the_o sense_n and_o therefore_o there_o can_v be_v no_o comfort_n but_o by_o pleasant_a sensation_n nay_o as_o such_o it_o be_v his_o comfort_n so_o music_n pleasant_a sight_n odour_n and_o agreeable_a object_n of_o all_o the_o sense_n be_v comfortable_a because_o pleasant_a i_o hope_v that_o none_o will_v say_v that_o music_n sight_n good_a news_n &c._n &c._n which_o high_o comfort_n have_v any_o spirit_n to_o add_v to_o we_o the_o
be_v well_o remove_v this_o prove_v how_o useful_a removal_n may_v be_v and_o how_o convenient_a in_o plague_n time_n it_o will_v be_v to_o remove_v to_o the_o wind-side_n of_o a_o town_n or_o city_n that_o be_v taint_v according_a as_o the_o wind_n change_v and_o how_o convenient_a wind_n be_v to_o convey_v away_o the_o effluviams_n and_o good_a stomachick_a cordial_n that_o be_v warm_a and_o pleasant_a to_o fortify_v the_o stomach_n and_o open_v the_o pore_n which_o all_o thing_n that_o cause_v a_o sense_n of_o pleasure_n do_v as_o wine_n spirit_n etc._n etc._n to_o which_o if_o some_o good_a preparation_n of_o opium_n be_v add_v it_o will_v be_v most_o convenient_a how_o many_o story_n have_v we_o of_o person_n well_o fill_v with_o wine_n who_o wonderful_o escape_v infection_n i_o pray_v god_n this_o hint_n may_v be_v improve_v to_o the_o preservation_n of_o mankind_n therefore_o i_o add_v that_o much_o may_v be_v in_o a_o good_a quantity_n of_o wine_n in_o this_o case_n 1._o because_o quod_fw-la intus_fw-la est_fw-la prohibet_fw-la alienum_fw-la that_o be_v what_o be_v within_o hinder_v ingress_n of_o another_o thing_n 2._o because_o the_o perspiration_n will_v be_v the_o great_a both_o upon_o the_o account_n of_o the_o great_a open_n of_o the_o pore_n by_o the_o pleasure_n of_o the_o wine_n and_o the_o great_a quantity_n of_o matter_n to_o be_v perspire_v carry_v off_o the_o venomous_a particle_n 3._o because_o the_o sensitive_a soul_n be_v thereby_o much_o comfort_v refresh_v and_o invigorate_v but_o i_o will_v have_v the_o wine_n so_o use_v as_o to_o keep_v a_o continual_a warmth_n pleasure_n and_o comfort_n at_o stomach_n which_o be_v the_o main_a cause_n of_o all_o the_o good_a i_o think_v a_o glass_n every_o hour_n after_o take_v 2_o or_o 3_o at_o first_o may_v hit_v the_o mark_n best_o the_o reason_n of_o which_o will_v appear_v hereafter_o three_o the_o stomach_n be_v exquisite_a disposition_n to_o sensation_n above_o all_o other_o organ_n and_o membrane_n appear_v by_o this_o viz._n that_o the_o offence_n of_o the_o other_o organ_n of_o sensation_n even_o by_o their_o proper_a object_n do_v often_o affect_v the_o stomach_n more_o than_o those_o very_a sense_n or_o organ_n themselves_o for_o instance_n if_o we_o smell_v a_o great_a stench_n the_o stomach_n be_v often_o more_o offend_v thereat_o than_o the_o nose_n as_o be_v manifest_a from_o the_o vomit_n faint_n and_o deliquium_n that_o be_v cause_v by_o the_o stomach_n upon_o that_o account_n so_o the_o bare_a see_v feel_v and_o taste_v of_o a_o nasty_a thing_n do_v cause_n nauseas_fw-la etc._n etc._n at_o stomach_n yea_o the_o very_a name_n of_o such_o thing_n have_v much_o offend_v it_o and_o cause_v such_o effect_n which_o may_v be_v think_v very_o strange_a consider_v that_o there_o pass_v no_o effluvias_fw-la from_o the_o sound_n of_o word_n but_o the_o reason_n will_v appear_v in_o the_o follow_a paragraph_n four_o all_o passion_n commotion_n and_o perturbation_n that_o happen_v in_o the_o body_n do_v often_o affect_v the_o stomach_n and_o sometime_o so_o grievous_o as_o to_o cause_n nauseas_fw-la vomit_n great_a anxiety_n at_o stomach_n faint_n etc._n etc._n thus_o fear_v terror_n surprise_v anger_n grief_n pain_n in_o other_o part_n etc._n etc._n cause_v some_o motion_n in_o the_o animal_n more_o than_o ordinary_a of_o which_o the_o stomach_n be_v sensible_a do_v cause_n the_o aforesaid_a disturbance_n therefore_o it_o be_v no_o wonder_n if_o the_o hear_v one_o mention_n a_o nasty_a thing_n which_o cause_v a_o abhorrence_n and_o the_o motion_n consequent_a thereunto_o shall_v as_o be_v say_v in_o the_o precedent_n paragraph_n cause_v the_o nice_a stomach_n to_o be_v offend_v it_o be_v most_o manifest_a from_o the_o premise_n that_o no_o organ_n or_o membrane_n can_v compare_v with_o the_o stomach_n as_o to_o its_o exquisite_a disposition_n for_o sensation_n it_o follow_v then_o that_o grievance_n or_o pleasure_n at_o stomach_n must_v have_v the_o great_a effect_n 1._o because_o the_o intenseness_n of_o either_o will_v be_v proportionable_a to_o the_o sensation_n 2._o because_o the_o power_n of_o the_o animal_n that_o be_v to_o defend_v it_o which_o be_v contraction_n be_v affect_v according_a to_o the_o sensation_n and_o that_o it_o be_v there_o most_o requisite_a sensible_o to_o affect_v they_o 3._o because_o what_o affect_v the_o stomach_n influence_n the_o whole_a animal_n more_o than_o the_o sensation_n of_o any_o other_o part._n 4._o because_o of_o the_o considerable_a stay_v that_o thing_n make_v at_o stomach_n to_o cause_n grievance_n or_o pleasure_n whereas_o that_o of_o pleasure_n be_v general_o very_o momentary_a in_o other_o case_n 5._o because_o be_v within_o the_o body_n we_o carry_v our_o pleasure_n or_o grievance_n with_o we_o as_o a_o vade_fw-la mecum_fw-la wherever_o we_o go_v and_o therefore_o 6._o it_o be_v a_o pleasure_n etc._n etc._n that_o can_v so_o well_o be_v take_v away_o from_o we_o as_o that_o of_o the_o tongue_n ear_n nose_n eye_n etc._n etc._n may_v by_o remove_v the_o object_n and_o therefore_o it_o remain_v with_o we_o in_o our_o very_a sleep_n as_o far_o as_o we_o be_v capable_a of_o sensation_n at_o that_o time_n cause_v pleasant_a dream_n etc._n etc._n and_o so_o agreeable_o entertain_v we_o sleep_v or_o wake_v when_o the_o pleasure_n of_o all_o the_o other_o sense_n fail_v we_o which_o will_v appear_v far_o hereafter_o the_o pleasure_n at_o stomach_n excel_v even_o that_o of_o venery_n if_o not_o in_o intenseness_n yet_o in_o several_a other_o respect_n viz._n 1._o because_o of_o its_o duration_n that_o of_o venus_n be_v momentary_a but_o that_o of_o wine_n at_o stomach_n last_v a_o good_a while_n and_o that_o of_o opium_n many_o hour_n it_o be_v therefore_o that_o the_o effect_n of_o these_o two_o be_v more_o remarkable_a and_o take_v notice_n of_o 2._o because_o that_o at_o stomach_n may_v be_v continue_v as_o long_o as_o we_o please_v by_o a_o new_a supply_n of_o wine_n opium_n cordial_n etc._n etc._n 3._o because_o it_o may_v be_v excite_v when_o and_o as_o often_o as_o we_o please_v if_o we_o have_v those_o cordial_n at_o hand_n 4._o because_o it_o be_v not_o attend_v with_o any_o expense_n of_o strength_n depression_n of_o spirit_n etc._n etc._n as_o that_o of_o venery_n but_o the_o quite_o contrary_a viz._n with_o more_o vigour_n elevation_n of_o the_o spirit_n etc._n etc._n one_o be_v by_o emission_n and_o the_o other_o upon_o admission_n of_o what_o be_v agreeable_a it_o be_v for_o the_o several_a reason_n contain_v in_o the_o premise_n that_o the_o effect_n of_o grievance_n as_o hunger_n etc._n etc._n or_o pleasure_n be_v more_o considerable_a and_o remarkable_a at_o stomach_n and_o that_o thing_n agreeable_a thereto_o have_v by_o way_n of_o eminence_n gain_v the_o name_n of_o cordial_n that_o wine_n spirit_n opium_n etc._n etc._n do_v cause_n a_o more_o permanent_a and_o notable_a gaity_n pleasantness_n good_a humour_n serenity_n promptitude_n ovation_n of_o the_o spirit_n or_o sensitive_a soul_n bravery_n courage_n magnanimity_n euphory_n or_o easy_a undergo_n of_o business_n relaxation_n with_o all_o its_o effect_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la perspiration_n etc._n etc._n which_o be_v hardly_o note_v in_o other_o short_a pleasure_n unless_o it_o be_v in_o that_o eminent_a though_o short_a one_o of_o venus_n which_o be_v a_o pleasure_n of_o the_o same_o sense_n of_o feel_v as_o that_o of_o opium_n and_o wine_n be_v therefore_o please_v the_o stomach_n be_v one_o of_o the_o great_a thing_n to_o be_v regard_v in_o the_o practice_n of_o physic_n to_o comfort_n satisfy_v or_o compose_v the_o spirit_n by_o which_o mean_n i_o have_v often_o perform_v such_o cure_n that_o neither_o i_o nor_o i_o suppose_v any_o other_o can_v otherwise_o perform_v namely_o dejection_n of_o appetite_n untowardness_n at_o stomach_n etc._n etc._n when_o all_o the_o ordinary_a and_o usual_a mean_n have_v fail_v by_o ask_v they_o what_o they_o most_o desire_a or_o long_v for_o and_o let_v they_o have_v it_o or_o if_o they_o can_v not_o tell_v of_o any_o thing_n that_o they_o long_v for_o i_o have_v mention_v to_o they_o all_o the_o relish_v thing_n that_o i_o can_v think_v of_o and_o such_o as_o be_v grateful_a to_o the_o stomach_n till_o they_o fasten_v upon_o somewhat_o that_o they_o like_v or_o fancy_v and_o then_o be_v give_v they_o it_o general_o have_v the_o desire_a success_n the_o stomach_n be_v grieve_v for_o it_o will_v concern_v we_o to_o know_v how_o because_o opium_n cause_v vomit_v etc._n etc._n general_o speak_v 1._o by_o thing_n hard_a of_o digestion_n as_o heavy_a bread_n mushroom_n rosin_n and_o such_o like_a 2._o by_o thing_n acrimonious_a or_o pungent_a as_o vomitory_n of_o asarabacca_n groundsil_n squill_n etc._n etc._n which_o abound_v with_o volatile_a salt_n 3._o by_o thing_n that_o stick_v to_o the_o stomach_n which_o
only_o the_o open_n of_o the_o pore_n so_o that_o i_o need_v add_v no_o more_o word_n about_o it_o for_o the_o fame_n cause_o must_v have_v the_o same_o effect_n therefore_o a_o intense_a and_o permanent_a pleasure_n must_v have_v all_o or_o much_o of_o the_o effect_n of_o sleep_n in_o general_n as_o have_v be_v show_v it_o can_v therefore_o be_v any_o wonder_n that_o opium_n cause_v sleep_n yet_o be_v there_o difference_n between_o sleep_n and_o pleasure_n upon_o other_o account_n though_o not_o upon_o the_o account_n of_o relaxation_n viz._n because_o 1._o that_o sleep_n require_v also_o a_o rest_n of_o spirit_n or_o the_o sensitive_a soul_n whereas_o relaxation_n by_o pleasure_n be_v consistent_a with_o motion_n of_o the_o spirit_n either_o by_o outward_a action_n or_o internal_a motion_n thereof_o by_o some_o inward_a cause_n hence_o it_o be_v first_o that_o we_o can_v labour_v travel_v dance_n etc._n etc._n and_o enjoy_v pleasure_n and_o its_o relaxation_n volantary_a motion_n which_o require_v only_o a_o particular_a contraction_n of_o some_o part_n by_o the_o dictate_v of_o the_o will_n or_o appetite_n be_v consistent_a with_o the_o general_a relaxation_n by_o reason_n of_o the_o prerogative_n of_o the_o will._n thus_o do_v we_o move_v though_o more_o relax_v or_o when_o most_o merry_a and_o please_v with_o wine_n nay_o some_o will_v walk_v in_o their_o sleep_n when_o extreme_o intâ—t_v upon_o a_o thing_n as_o when_o awake_a which_o show_v the_o roll_a power_n of_o intentive_a contraction_n that_o may_v be_v exercise_v with_o relaxation_n and_o other_o contraction_n as_o the_o will_n itself_o may_v or_o intentive_a appetite_n second_o that_o pain_n be_v often_o take_v away_o by_o opium_n by_o the_o diversion_n and_o relaxation_n cause_v by_o pleasure_n and_o its_o inconsistence_n with_o pain_n without_o sleep_n which_o require_v the_o aforesaid_a rest_n that_o bare_a relaxation_n as_o such_o do_v not_o include_v though_o relaxation_n suffice_v to_o take_v away_o pain_n three_o that_o opium_n do_v by_o its_o heat_n active_a particle_n etc._n etc._n hinder_v some_o person_n to_o sleep_n yet_o have_v you_o in_o both_o these_o last_o case_n all_o other_o effect_n of_o opium_n as_o pleasure_n indolence_n relaxation_n etc._n etc._n which_o show_v how_o far_o sleep_v be_v from_o be_v a_o constant_a and_o the_o most_o genuine_a effect_n of_o opium_n as_o be_v general_o imagine_v however_o we_o must_v allow_v it_o as_o have_v be_v show_v to_o be_v a_o mighty_a disposer_n of_o we_o towards_o sleep_n because_o of_o the_o relaxation_n that_o it_o cause_n which_o be_v the_o main_a requisite_a of_o sleep_n ii_o that_o pleasure_n do_v without_o nutritive_a refection_n by_o the_o complacency_n it_o cause_v in_o the_o sensitive_a soul_n produce_v comfort_n satisfaction_n composure_n elevation_n of_o the_o spirit_n euphory_n etc._n etc._n of_o which_o sleep_n be_v either_o not_o at_o all_o capable_a or_o but_o in_o a_o low_a degree_n proportionable_a to_o the_o sensation_n that_o it_o have_v which_o be_v but_o little_a however_o a_o pleasure_n that_o remain_v within_o we_o even_o in_o our_o sleep_n as_o that_o of_o opium_n may_v well_o cause_v pleasant_a dream_n etc._n etc._n the_o reader_n may_v observe_v that_o in_o all_o place_n where_o i_o mention_v that_o relaxation_n cause_v the_o open_n of_o the_o pore_n that_o i_o speak_v only_o of_o perspiration_n as_o the_o effect_n thereof_o without_o mention_v sweat_n 1._o because_o perspiration_n be_v the_o only_a constant_a and_o infallible_a effect_n thereof_o by_o reason_n that_o the_o levity_n of_o the_o fume_n cause_v they_o as_o certain_o to_o pass_v at_o the_o pore_n when_o open_a as_o smoke_n pass_v up_o at_o a_o open_a chimney_n 2._o because_o sweat_n be_v a_o uncertain_a effect_n thereof_o for_o it_o require_v that_o the_o body_n be_v well_o fill_v with_o moisture_n though_o there_o be_v a_o relaxation_n or_o open_v of_o the_o pore_n as_o hypocrates_n very_o right_o intimate_v in_o that_o aphorism_n of_o his_o that_o i_o cite_v in_o the_o last_o chapter_n 1._o because_o sweat_n have_v not_o that_o levity_n that_o the_o fume_n have_v to_o cause_v it_o ready_o to_o move_v as_o soon_o as_o the_o pore_n be_v open_a 2._o because_o relaxation_n be_v more_o apt_a to_o receive_v detain_v and_o suspend_v humour_n 3._o because_o the_o protrusive_a motion_n of_o the_o heart_n be_v weak_a in_o all_o relaxation_n and_o all_o see_v how_o much_o its_o vigorous_a protrusion_n contribute_v to_o sweat_v upon_o action_n 4._o because_o a_o heartful_a of_o blood_n do_v not_o make_v such_o a_o push_v forward_o when_o the_o artery_n be_v widen_v by_o relaxation_n 5._o sweat_n have_v more_o of_o continuity_n consistence_n and_o viscidity_n can_v flow_v out_o so_o ready_o at_o the_o pore_n as_o a_o mere_a vapour_n however_o if_o the_o body_n be_v full_a of_o moisture_n and_o the_o pore_n open_a there_o be_v a_o natural_a course_n that_o way_n and_o the_o heart_n continual_o protrude_a it_o far_o and_o far_o a_o sweat_n follow_v and_o that_o whether_o they_o sleep_v or_o not_o 3._o because_o sweat_v as_o be_v in_o some_o sort_n intimate_v be_v sometime_o cause_v by_o the_o strong_a protrusion_n of_o the_o heart_n as_o in_o motion_n etc._n etc._n and_o upon_o that_o account_n come_v more_o under_o the_o title_n of_o flux_n cause_v by_o contraction_n than_o relaxation_n of_o which_o perspiration_n be_v a_o constant_a effect_n 4._o because_o sweat_n be_v sometime_o cause_v by_o another_o sort_n of_o contraction_n viz._n the_o compression_n of_o the_o whole_a body_n by_o a_o violent_a defensive_a contraction_n as_o in_o great_a terror_n agony_n and_o the_o like_a cause_v thereby_o as_o be_v show_v by_o the_o comparison_n of_o a_o wet_a sheet_n wring_v who_o out_o side_n be_v cold_a a_o cold_a sweat_n which_o that_o of_o alum_n or_o vitriol_n cause_v a_o exudation_n of_o the_o spital_n into_o the_o mouth_n by_o constr_v the_o part_n do_v illustrate_v very_o plain_o therefore_o you_o see_v i_o have_v just_a cause_n not_o to_o mention_v sweat_n as_o a_o certain_a and_o proper_a effect_n of_o relaxation_n without_o good_a distinction_n first_o make_v though_o unwary_a author_n that_o talk_v any_o thing_n one_o after_o another_o not_o know_v what_o they_o say_v make_v it_o their_o common_a say_n that_o sleep_n and_o opium_n stop_v all_o flux_n but_o sweat_n whereas_o they_o shall_v have_v rather_o say_v but_o perspiration_n for_o opium_n and_o sleep_n also_o will_v sometime_o hinder_v sweat_n viz._n that_o from_o pain_n terror_n etc._n etc._n and_o that_o as_o happen_v just_a upon_o awake_v by_o the_o strong_a systole_n of_o the_o heart_n and_o contraction_n of_o the_o whole_a body_n and_o that_o also_o upon_o motion_n unless_o the_o body_n be_v as_o be_v say_v full_a of_o humour_n or_o moisture_n therefore_o it_o be_v a_o vulgar_a error_n to_o say_v sweat_n instead_o of_o perspiration_n in_o the_o case_n aforesaid_a you_o may_v remember_v that_o in_o the_o beginning_n of_o this_o chapter_n i_o conclude_v that_o a_o sal-volatile-oleosum_a such_o as_o semen_n humanum_fw-la wherein_o the_o oily_a and_o volatile_a part_n be_v strict_o combine_v and_o the_o volatile_a somewhat_o more_o active_a or_o acrimonious_a than_o that_o in_o our_o membrane_n in_o general_a must_v be_v most_o please_v to_o the_o membrane_n by_o a_o fine_a titillation_n etc._n etc._n therefore_o if_o opium_n shall_v prove_v to_o be_v such_o we_o need_v not_o wonder_v at_o its_o titillate_v to_o venery_n nor_o indeed_o its_o cause_v a_o high_a sense_n of_o pleasure_n upon_o any_o membrane_n they_o be_v all_o of_o the_o same_o nature_n but_o especial_o upon_o the_o most_o exquisite_o dispose_v membrane_n of_o the_o stomach_n and_o the_o venereal_a part_n nor_o consequent_o its_o cause_v all_o the_o aforementioned_a effect_n of_o intense_a pleasure_n as_o comfort_n satisfaction_n ovation_n etc._n etc._n of_o the_o sensitive_a soul_n or_o spirit_n and_o relaxation_n of_o all_o the_o sensile_a part_n which_o will_v easy_o solve_v all_o the_o phenomenas_n of_o opium_n however_o numerous_a mysterious_a and_o seem_o contradictory_n as_o you_o will_v find_v let_v we_o therefore_o now_o see_v whether_o opium_n be_v such_o a_o sal-volatile-oleosum_a wherein_o the_o volatile_a particle_n be_v somewhat_o more_o active_a or_o acrimonious_a than_o we_o and_o the_o oily_a and_o volatile_a part_n strict_o combine_v if_o so_o the_o business_n be_v do_v the_o nail_n be_v hit_v on_o the_o head_n and_o i_o may_v say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d chap._n xv._o show_v what_o be_v the_o principle_n of_o opium_n and_o which_o cause_n the_o good_a and_o bad_a effect_n thereof_o have_v try_v if_o not_o tire_v your_o patience_n and_o premise_v what_o i_o think_v necessary_a in_o the_o forego_n chapter_n i_o now_o reassume_v the_o thread_n of_o my_o discourse_n as_o for_o the_o passive_a principle_n of_o opium_n which_o do_v or_o signify_v little_a or_o nothing_o
spoon_n and_o cause_n no_o more_o effect_n than_o oil_n of_o olive_n and_o spirit_n of_o sal_fw-la amenoniack_a take_v inward_o one_o act_v too_o soft_o lazy_o and_o greasy_o to_o cause_v any_o brisk_a and_o agreeable_a ovation_n of_o the_o spirit_n and_o the_o other_o too_o rude_o sting_v the_o membrane_n therefore_o we_o must_v proceed_v in_o our_o enquiry_n four_o opium_n have_v a_o sort_n of_o resinous_n sulphur_n that_o be_v loose_a and_o not_o unite_v with_o the_o volatile_a salt_n which_o plain_o appear_v 1._o because_o if_o you_o dissolve_v opium_n in_o water_n cold_a or_o hot_a or_o any_o watery_a menstruum_fw-la you_o will_v find_v a_o good_a quantity_n of_o rosin_n undissolved_a at_o bottom_n while_o the_o volatile_a salt_n be_v all_o or_o most_o dissolve_v in_o the_o water_n especial_o if_o the_o water_n be_v often_o repeat_v and_o quite_o separate_v from_o the_o resinous_n part_v which_o subside_v without_o any_o more_o trouble_n which_o show_v that_o the_o volatile_a salt_n and_o it_o be_v not_o combine_v but_o in_o a_o very_a loose_a and_o distinct_a manner_n 2._o because_o if_o you_o first_o dissolve_v opium_n in_o spirit_n of_o wine_n which_o imbibe_v the_o rosin_n it_o be_v easy_o again_o precipitate_v by_o plain_a water_n leave_v behind_o it_o all_o or_o most_o of_o the_o volatile_a salt_n in_o the_o form_n of_o a_o red_a tincture_n in_o the_o menstruum_fw-la as_o it_o do_v also_o in_o the_o former_a case_n note_v that_o the_o resinous_n part_n of_o opium_n have_v no_o effect_n as_o a_o opiate_n for_o if_o it_o be_v well_o wash_v with_o water_n as_o be_v say_v it_o have_v no_o operation_n of_o that_o kind_n or_o so_o little_a that_o it_o be_v not_o worth_a the_o mind_v but_o all_o the_o virtue_n specific_a taste_n smell_v etc._n etc._n be_v carry_v away_o in_o that_o red_a tincture_n which_o have_v all_o the_o good_a effect_n of_o opium_n as_o experience_n assure_v we_o 3._o because_o if_o opium_n be_v very_o much_o torrefy_v most_o of_o the_o volatile_a salt_n be_v evaporate_v and_o with_o it_o most_o if_o not_o all_o the_o virtue_n of_o opium_n but_o the_o rosin_n remain_v as_o a_o deadish_a stuff_n in_o respect_n of_o the_o good_a effect_n of_o opium_n though_o it_o be_v as_o shall_v be_v prove_v the_o producer_n of_o the_o ill_a effect_n thereof_o therefore_o this_o rosin_n must_v be_v whole_o reject_v five_o the_o red_a tincture_n aforesaid_a have_v all_o or_o most_o of_o the_o volatile_a salt_n in_o it_o 1._o because_o water_n be_v the_o proper_a menstruum_fw-la for_o saline_n thing_n and_o that_o the_o tincture_n reduce_v to_o a_o extract_n give_v very_o much_o in_o moist_a wether_n which_o quality_n it_o must_v have_v from_o the_o volatile_a salt_n because_o it_o have_v very_o little_o fix_v salt_n 2._o because_o the_o specific_a bitterness_n which_o proceed_v from_o volatile_a salt_n and_o oily_a part_n be_v whole_o in_o that_o red_a tincture_n 3._o because_o that_o tincture_n have_v also_o the_o specific_a rankness_n of_o smell_n that_o the_o volatile_a salt_n as_o be_v show_v give_v the_o opium_n by_o the_o help_n of_o some_o oily_a part_n 4._o because_o that_o tincture_n reduce_v to_o a_o extract_n have_v the_o bite_a taste_n of_o opium_n which_o as_o be_v show_v proceed_v from_o its_o volatile_a salt_n 5._o because_o that_o extract_n incides_fw-la discuss_n resolve_n be_v psilothrick_n titillate_n to_o venery_n cause_v itch_n in_o the_o skin_n acrimonious_a sweat_v etc._n etc._n all_o which_o be_v as_o be_v show_v the_o effect_n of_o volatile_a salt_n but_o what_o need_v i_o insist_v so_o much_o upon_o its_o effect_n to_o prove_v it_o when_o 6._o it_o appear_v by_o crystalization_n of_o the_o say_a tincture_n after_o it_o have_v be_v evaporate_v to_o a_o due_a degree_n that_o it_o contain_v the_o volatile_a salt_n in_o it_o which_o in_o a_o cool_a place_n shoot_v to_o elegant_a crystal_n and_o that_o 7._o it_o be_v find_v therein_o by_o chemical_a operation_n by_o fire_n six_o the_o say_a tincture_n be_v oleose_v 1._o because_o the_o redness_n of_o the_o tincture_n must_v be_v from_o oily_a part_n for_o pure_a sincere_a volatile_a salt_n give_v no_o such_o tincture_n 2._o because_o it_o be_v bitter_a one_o ingredient_n of_o which_o taste_n be_v ever_o oily_a part_n as_o be_v say_v 3._o because_o of_o its_o rank_a smell_n like_o sem._n viril_n which_o prove_v it_o to_o be_v sulphureous_a for_o the_o volatile_a salt_n alone_o have_v only_o a_o quick_a smell_n or_o urinous_a at_o far_a 4._o because_o it_o be_v of_o a_o hot_a taste_n when_o reduce_v to_o a_o extract_n which_o heat_v of_o taste_n consider_v distinct_o from_o its_o pungent_a or_o bite_a taste_n must_v be_v from_o sulphureous_a or_o oily_a part_n 5._o because_o spirit_n of_o wine_n and_o other_o spirituosulphureous_a menstruum_n do_v ready_o dissolve_v it_o when_o reduce_v to_o a_o extract_n 6._o because_o the_o extract_n soften_v with_o dry_a warmth_n as_o sulphureous_a or_o oily_a thing_n do_v 7._o because_o a_o true_a sal-volatile-oleosum_a wherein_o the_o volatile_a salt_n and_o oily_a part_n be_v intimate_o combine_v as_o you_o find_v in_o all_o blood_n tincture_n of_o several_a plant_n that_o have_v such_o a_o sal-volatile-oleosum_a be_v red_a 8._o because_o it_o can_v not_o otherwise_o so_o fine_o please_v the_o membrane_n cause_n sleep_n compose_v the_o spirit_n etc._n etc._n if_o it_o be_v all_o volatile_a salt_n which_o be_v whole_o pungent_a and_o acrimonious_a mighty_o oppose_v sleep_n and_o cause_v a_o great_a stir_n in_o the_o blood_n and_o spirit_n but_o as_o i_o say_v as_o to_o its_o volatile_a salt_n what_o need_v i_o insist_v upon_o its_o effect_n when_o 10._o it_o be_v inflammability_n after_o it_o be_v reduce_v to_o a_o extract_n and_o dry_v put_v it_o out_o of_o all_o question_n and_o that_o 11._o a_o oil_n may_v be_v separate_v from_o the_o volatile_a salt_n though_o not_o without_o trouble_n because_o that_o as_o be_v requisite_a to_o complete_a it_o in_o the_o high_a degree_n seven_o the_o oily_a part_n and_o volatile_a salt_n be_v very_o intimate_o and_o strict_o combine_v as_o fair_o appear_v 1._o by_o the_o difficulty_n to_o separate_v they_o 2._o by_o the_o redness_n of_o the_o tincture_n as_o in_o blood_n etc._n etc._n for_o when_o oily_a or_o sulphureous_a particle_n be_v loose_a therein_o they_o make_v either_o a_o white_a colour_n as_o the_o rosin_n do_v in_o the_o drop_n that_o fall_v out_o of_o the_o incision_n in_o the_o head_n of_o the_o poppy_n which_o be_v milk_n white_a or_o leave_v the_o volatile_a spirit_n perspicuous_a as_o in_o a_o sort_n of_o artificial_a sal._n volatile-oleosum_a that_o be_v sell_v at_o the_o apothecary_n shop_n in_o london_n 3._o because_o it_o impart_v its_o tincture_n which_o depend_v upon_o both_o to_o all_o menstruum_n 4._o because_o it_o impart_v its_o virtue_n which_o depend_v upon_o both_o to_o all_o menstruum_n 5._o because_o it_o impart_v its_o specific_a smell_n which_o depend_v upon_o both_o to_o all_o menstruumt_v 6._o because_o it_o impart_v its_o specific_a hot_a and_o bite_a taste_n which_o depend_v upon_o both_o the_o oily_a and_o volatile_a particle_n to_o all_o menstruum_n 7._o because_o it_o will_v hold_v its_o virtue_n many_o year_n which_o it_o can_v not_o if_o the_o volatile_a salt_n and_o oily_a part_n be_v not_o very_o strict_o combine_v 8._o because_o that_o notwithstanding_o the_o digestion_n at_o stomach_n it_o have_v hold_v its_o specific_a virtue_n smell_v and_o taste_n after_o it_o have_v be_v in_o it_o 4_o 5_o 6_o 7_o 8_o 9_o 10_o 11_o 12_o 18_o or_o more_o hour_n as_o appear_v by_o its_o operate_n so_o long_o and_o afteward_n its_o be_v vomit_v up_o with_o the_o same_o taste_n and_o smell_v that_o it_o have_v at_o first_o than_o which_o there_o can_v be_v a_o great_a argument_n 9_o because_o it_o have_v be_v carry_v off_o by_o stool_n which_o have_v its_o specific_a smell_n after_o many_o hour_n remain_v in_o the_o stomach_n 10._o because_o its_o operation_n in_o general_n last_v long_o charas_fw-la mention_n one_o that_o it_o operate_v with_o for_o about_o 30_o hour_n and_o wedelius_n another_o who_o opium_n cause_v to_o vomit_v constant_o about_o 18_o hour_n after_o it_o be_v take_v 11._o because_o it_o have_v its_o effect_n upon_o the_o venereal_a membrane_n after_o it_o have_v pass_v the_o digestion_n at_o stomach_n the_o effect_n of_o the_o choler_n and_o succus_fw-la pancreatus_fw-la in_o the_o duodenum_fw-la be_v strain_v through_o the_o coat_n of_o the_o intestine_n into_o the_o lacteal_v and_o through_o the_o glandule_n of_o the_o mesentery_n mix_v and_o circulate_v with_o the_o blood_n etc._n etc._n 12._o because_o after_o all_o that_o it_o have_v its_o effect_n upon_o the_o skin_n by_o cause_v a_o itch_a therein_o 13._o because_o it_o not_o only_a cause_n acrimonious_a sweat_v but_o such_o as_o evident_o smell_v thereof_o
contraction_n by_o which_o vomit_v be_v perform_v 4._o it_o still_v hiccough_n for_o the_o same_o reason_n 5._o it_o cause_v convulsion_n and_o contraction_n to_o cease_v 1._o because_o it_o induce_v a_o relaxation_n which_o take_v they_o off_o 2._o by_o take_v off_o the_o sense_n which_o the_o irritate_v cause_n 3._o by_o compose_v the_o spirit_n 6._o it_o cause_v the_o meat_n to_o stay_v long_o at_o stomach_n as_o sleep_n do_v 1._o by_o relax_v the_o stomach_n so_o that_o it_o be_v not_o subject_a to_o contract_v to_o send_v it_o out_o 2._o by_o still_v all_o motion_n whereby_o the_o stomach_n grow_v proportionable_o unactive_a 3._o because_o the_o relaxation_n oppose_v the_o contraction_n by_o which_o the_o menstruum_fw-la be_v send_v into_o the_o stomach_n or_o the_o saliva_n into_o the_o mouth_n both_o which_o be_v therefore_o much_o want_v in_o sleep_n for_o the_o like_a reason_n as_o have_v be_v show_v 7._o it_o moderate_v and_o prevent_v hunger_n 1._o because_o as_o be_v say_v the_o menstruum_fw-la be_v not_o so_o plentiful_o send_v or_o squeeze_a into_o the_o relaxed_a stomach_n 2._o because_o it_o take_v away_o the_o sense_n of_o hunger_n 3._o because_o it_o leave_v the_o meat_n to_o stay_v too_o long_o at_o stomach_n by_o reason_n that_o it_o be_v relax_v more_o insensible_a and_o proportionable_o languid_a in_o motion_n as_o in_o sleep_n 8._o it_o cause_v sweat_v when_o the_o body_n be_v full_a of_o moisture_n as_o sleep_n do_v by_o relax_v and_o thereby_o open_v the_o pore_n and_o not_o as_o people_n common_o talk_v by_o attenuate_v and_o the_o like_a for_o a_o grain_n of_o opium_n bear_v no_o proportion_n to_o the_o blood_n and_o humour_n that_o it_o cause_v it_o mere_o as_o sleep_n do_v be_v manifest_a not_o only_o because_o it_o bear_v not_o a_o due_a proportion_n to_o the_o work_n as_o a_o alterative_a but_o because_o man_n do_v not_o sweat_v in_o that_o case_n as_o in_o sleep_n without_o much_o moisture_n in_o the_o body_n whereas_o much_o will_v not_o be_v attenuate_v as_o soon_o as_o less_o therefore_o it_o be_v only_o a_o exudation_n of_o the_o humour_n upon_o a_o plenty_n thereof_o and_o open_v of_o the_o pore_n sanctorius_n sect._n 1_o aph._n 22._o invisibilis_fw-la perspiratio_fw-la fit_a visibilis_fw-la quando_fw-la nutrimentum_fw-la est_fw-la nimium_fw-la that_o be_v invisible_a perspiration_n become_v visible_a sweat_n when_o nourishment_n or_o moisture_n be_v too_o much_o which_o exact_o agree_v with_o that_o of_o hypocrates_n cite_v in_o chap._n 13._o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d etc._n etc._n 9_o it_o cause_v the_o menses_fw-la to_o flow_v when_o nothing_o be_v want_v but_o the_o open_n or_o relax_v of_o the_o viae_fw-la or_o pore_n they_o issue_v out_o at_o as_o when_o they_o be_v natural_o too_o narrow_a and_o close_a as_o upon_o the_o first_o tendency_n to_o they_o in_o young_a girl_n or_o when_o stop_v by_o reason_n of_o any_o undue_a contraction_n thereof_o as_o by_o pain_n cold_a sorrow_n or_o other_o grievous_a passion_n all_o which_o do_v close_o the_o pore_n beside_o it_o do_v irritate_fw-la those_o very_a sensile_a venereal_a part_n to_o erection_n and_o i_o have_v reason_n to_o think_v that_o it_o do_v by_o a_o general_a relaxation_n cause_n a_o increase_n of_o blood_n as_o it_o do_v of_o the_o breast_n milk_n etc._n etc._n cause_v as_o it_o be_v a_o artificial_a puberty_n or_o at_o least_o much_o promote_a the_o natural_a and_o therefore_o be_v of_o excellent_a use_n in_o this_o case_n in_o judicious_a hand_n though_o little_a thought_n of_o in_o practice_n obj._n here_o i_o may_v be_v sure_a of_o a_o objection_n that_o it_o stop_v all_o flux_n but_o sweat_v or_o perspiration_n ans._n it_o be_v as_o false_a as_o it_o be_v a_o common_a say_n if_o they_o do_v not_o mean_v only_o such_o flux_n as_o proceed_v from_o grievous_a sensation_n and_o contraction_n thereupon_o for_o how_o can_v that_o which_o relax_n all_o part_n stop_v any_o flux_n that_o depend_v upon_o relaxation_n as_o stillicidium_fw-la urinae_fw-la by_o relaxation_n of_o the_o sphincter_n of_o the_o â—ladder_n involuntary_a flux_n per_fw-la anum_fw-la by_o the_o 〈◊〉_d of_o its_o sphincter_n and_o such_o like_a so_o do_v i_o speak_v of_o a_o flux_n that_o may_v often_o depend_v upon_o relaxation_n as_o i_o have_v show_v obj._n but_o it_o may_v be_v object_v that_o it_o particular_o stanche_n blood_n how_o then_o shall_v it_o promote_v the_o menses_fw-la ans._n experience_n tell_v i_o it_o do_v and_o reason_n confirm_v it_o it_o stanche_n blood_n by_o compose_v the_o fury_n of_o its_o motion_n but_o that_o do_v not_o hinder_v but_o it_o may_v relax_v the_o pore_n for_o sweat_n menses_fw-la lochia_n etc._n etc._n to_o pass_v and_o why_o not_o for_o the_o menses_fw-la and_o lochia_n as_o well_o as_o sweat_v by_o open_v the_o pore_n i_o will_v fain_o know_v consider_v also_o the_o titillation_n that_o it_o cause_n upon_o those_o venereal_a part_n which_o may_v very_o much_o solicit_v their_o motion_n 10._o it_o cause_v the_o lochia_n to_o flow_v for_o the_o same_o reason_n that_o it_o do_v the_o menses_fw-la this_o i_o have_v great_a experience_n in_o note_v that_o the_o menses_fw-la lochia_n and_o perspiration_n be_v natural_a evacuation_n that_o have_v pore_n design_v for_o they_o by_o nature_n the_o open_n of_o which_o by_o relaxation_n must_v make_v way_n for_o they_o suppose_v when_o the_o blood_n flow_v so_o much_o into_o the_o skin_n as_o to_o cause_v a_o efflorescence_n by_o the_o relaxation_n thereof_o after_o opium_n be_v take_v that_o there_o be_v pore_n to_o carry_v out_o blood_n as_o there_o be_v for_o sweat_n why_o shall_v not_o one_o flow_v as_o well_o as_o the_o other_o but_o there_o be_v such_o pore_n for_o the_o menses_fw-la and_o lochia_n and_o large_a one_o too_o and_o therefore_o it_o must_v promote_v they_o and_o why_o shall_v not_o relaxation_n do_v it_o as_o well_o as_o contraction_n by_o cold_a terror_n grief_n etc._n etc._n stop_v they_o for_o the_o effect_n of_o contrary_n be_v contrary_a 11._o it_o cause_v the_o stone_n to_o pass_v 1._o because_o it_o reâ—_n and_o so_o widen_v the_o passage_n 2._o because_o it_o 〈◊〉_d move_v with_o little_a or_o no_o pain_n which_o contract_v the_o part_n and_o so_o hinder_v its_o passage_n therefore_o the_o use_n of_o opium_n with_o some_o other_o help_v be_v the_o great_a mean_n that_o can_v be_v or_o ever_o will_v be_v for_o the_o stone_n till_o the_o dissolution_n of_o it_o be_v find_v out_o not_o only_o to_o give_v ease_n in_o the_o case_n of_o the_o stone_n but_o to_o cause_v it_o to_o pass_v for_o both_o which_o purpose_v it_o excel_v all_o thing_n and_o do_v both_o at_o once_o 12._o it_o cause_v the_o delivery_n of_o woman_n by_o relax_v the_o neck_n of_o the_o womb_n as_o it_o do_v that_o of_o the_o bladder_n to_o deliver_v person_n of_o the_o stone_n but_o in_o the_o delivery_n of_o woman_n it_o be_v not_o to_o be_v use_v but_o in_o particular_a case_n and_o by_o a_o very_a skilful_a hand_n 1._o because_o it_o be_v apt_a to_o take_v off_o all_o the_o woman_n pain_n and_o throw_v and_o so_o quite_o disappoint_v the_o delivery_n for_o a_o day_n 2_o 3_o 4_o or_o more_o sometime_o 2._o because_o it_o cause_v a_o great_a relaxation_n the_o part_n after_o delivery_n will_v be_v very_o unapt_a to_o close_v and_o contract_v due_o as_o they_o shall_v in_o such_o case_n otherwise_o several_a inconvenience_n may_v ensue_v 3._o it_o may_v be_v pernicious_a upon_o the_o account_n of_o the_o evacuation_n of_o blood_n that_o then_o happen_v but_o these_o thing_n belong_v more_o proper_o to_o the_o use_v of_o opium_n in_o cure_n 13._o it_o cause_v deadness_n of_o the_o eye_n as_o in_o drunkeness_n etc._n etc._n because_o the_o cornea_n be_v relax_v so_o that_o the_o humour_n do_v not_o fill_v it_o up_o to_o a_o tense_n rotundity_n as_o when_o it_o be_v more_o contract_v 14._o it_o cause_v the_o pupilla_fw-la to_o dilate_v because_o of_o the_o same_o relaxation_n 15._o it_o cause_v a_o growth_n of_o the_o breast_n penis_n and_o increase_v of_o milk_n by_o reason_n of_o the_o same_o relaxation_n as_o the_o pleasure_n of_o the_o semen_n upon_o puberty_n do_v or_o as_o emollient_n and_o relaxer_n apply_v to_o the_o breast_n increase_v milk_n etc._n etc._n by_o make_v more_o room_n for_o it_o etc._n etc._n 16._o it_o cause_v venereal_a dream_n because_o of_o the_o titillation_n of_o the_o venereal_a membrane_n that_o it_o cause_n 17._o it_o cause_v nocturnal_a pollution_n for_o the_o same_o reason_n and_o because_o it_o relax_n the_o part_n 18._o it_o cause_v itch_n in_o the_o skin_n because_o of_o its_o titillation_n by_o its_o volatile_a salt_n 19_o it_o cause_v much_o urine_n as_o cantbaride_n bee_n pismire_n millepedes_n etc._n etc._n do_v by_o its_o volatile_a salt_n which_o titillate_n and_o irritate_v those_o
part_n by_o its_o relax_v the_o pore_n of_o the_o kidney_n and_o render_v the_o humour_n more_o penetrate_v in_o some_o measure_n by_o the_o volatile_a salt_n 20._o it_o cause_v a_o nausea_n by_o its_o rosin_n stick_v to_o and_o teaze_v the_o sensile_a coat_n of_o the_o stomach_n the_o reason_n why_o it_o be_v general_o so_o long_o before_o it_o cause_v a_o nausea_n or_o vomit_v be_v that_o its_o pleasure_n do_v at_o first_o prevent_v it_o till_o at_o last_o the_o stick_a rosin_n urge_v it_o by_o its_o long_a stay_n and_o vexatious_a adherence_n 21._o it_o cause_v swimmings_n in_o the_o head_n by_o consent_n when_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o you_o find_v upon_o nauseas_fw-la before_o vomit_v or_o when_o any_o thing_n do_v much_o offend_v the_o stomach_n as_o much_o drink_n or_o wine_n which_o when_o they_o have_v vomit_v those_o swimming_n cease_v 22._o it_o cause_v watch_v in_o some_o person_n who_o be_v of_o very_o movable_a spirit_n by_o actuate_a and_o stir_v their_o spirit_n by_o its_o active_a volatile_a salt_n though_o it_o do_v at_o the_o same_o time_n please_v the_o membrane_n and_o consequent_o relax_v the_o sensile_a part_n and_o thereby_o cause_n indolence_n the_o effect_n of_o relaxation_n which_o it_o also_o do_v when_o people_n keep_v themselves_o from_o sleep_n by_o voluntary_a motion_n and_o therefore_o take_v away_o pain_n even_o when_o man_n travel_v etc._n etc._n beside_o there_o be_v some_o sort_n of_o person_n that_o upon_o joy_n good_a news_n pleasure_n or_o the_o like_a be_v too_o much_o elevate_v or_o have_v a_o restless_a ovation_n of_o the_o spirit_n which_o will_v not_o suffer_v they_o to_o sleep_n though_o they_o be_v in_o a_o pleasant_a condition_n all_o the_o time_n this_o may_v be_v the_o case_n of_o some_o that_o can_v sleep_v after_o opium_n though_o they_o be_v all_o the_o time_n as_o they_o call_v it_o in_o a_o heavenly_a condition_n for_o as_o i_o have_v say_v a_o quietness_n of_o the_o spirit_n be_v requisite_a to_o cause_v sleep_n as_o well_o as_o relaxation_n but_o relaxation_n alone_o and_o thereby_o expansion_n of_o the_o spirit_n so_o that_o they_o can_v carry_v impression_n smart_o be_v sufficient_a to_o cause_v indolence_n and_o the_o pleasure_n to_o cause_v a_o heavenly_a or_o very_o pleasant_a condition_n sanctor_n stat._n med._n sect._n 7._o aph._n 28._o say_v that_o laetitia_n perseverans_fw-la per_fw-la multos_fw-la dies_fw-la somnum_fw-la impedit_fw-la persevere_v pleasure_n may_v do_v the_o same_o by_o like_a reason_n that_o be_v too_o much_o 〈◊〉_d or_o ovation_n of_o the_o spirit_n sometime_o too_o large_a a_o do_v cause_n watch_v by_o over-actuating_a and_o exciting_a the_o spirit_n medicum_fw-la vini_fw-la generosi_fw-la &_o allium_fw-la say_v sanctorius_n conciliant_fw-la somnum_fw-la &_o perspirationem_fw-la si_fw-la vero_fw-la plus_fw-la justo_fw-la sumantur_fw-la utrumque_fw-la prohibent_fw-la perspirabile_fw-la tamen_fw-la in_o sudorem_fw-la convertunt_fw-la that_o be_v a_o little_a generous_a wine_n and_o garlic_n will_v cause_v sleep_n and_o perspiration_n but_o too_o much_o hinder_v both_o yet_o they_o convert_v the_o perspirable_a matter_n to_o a_o sweat_n which_o wine_n and_o garlick_n have_v the_o nature_n of_o opiate_n and_o the_o reason_n why_o they_o sweat_v be_v the_o quantity_n of_o the_o wine_n afford_v more_o moisture_n hypocrates_n say_v 23._o a_o dubious_a state_n between_o sleep_v and_o wake_v be_v cause_v when_o the_o relaxation_n upon_o the_o pleasure_n of_o opium_n incline_v to_o sleep_v but_o the_o irreâ—uiete_a ovation_n of_o the_o spirit_n by_o the_o pleasure_n and_o titillation_n will_v hardly_o suffer_v it_o yet_o high_o please_v and_o put_v they_o in_o a_o sweet_a agreeable_a condition_n chap._n xix_o the_o explication_n of_o the_o rare_a effect_n of_o opium_n in_o a_o moderate_a do_v 1._o it_o cause_v temporary_a pulse_n of_o the_o 〈◊〉_d and_o sometime_o of_o other_o part_n by_o its_o over_o relax_v the_o part_n and_o cause_v thereby_o a_o expansion_n of_o the_o elastic_a spirit_n which_o as_o be_v demonstrate_v weaken_v their_o motion_n 2._o falter_v of_o the_o tongue_n do_v as_o in_o relaxation_n by_o drunkenness_n proceed_v from_o the_o same_o cause_n 3._o looseness_n of_o the_o low_a jaw_n as_o you_o see_v in_o the_o drowsy_a and_o drunken_a people_n be_v from_o the_o same_o relaxation_n 4._o it_o sometime_o prevent_v sweat_n by_o cause_v a_o very_a liberal_a perspiration_n as_o be_v show_v for_o as_o sanctorius_n say_v who_o shall_v know_v it_o much_o insensible_a perspiration_n and_o sweat_n can_v consist_v especial_o in_o a_o temperate_a person_n who_o eat_v and_o drink_v moderate_o therefore_o if_o you_o keep_v a_o person_n that_o sweat_v much_o at_o night_n in_o a_o free_a perspiration_n all_o day_n by_o the_o help_n of_o a_o opiate_n you_o will_v much_o lessen_v or_o total_o prevent_v the_o sweat_n at_o night_n as_o in_o consumptive_a person_n etc._n etc._n 5._o it_o cause_v abortion_n by_o relax_v the_o neck_n of_o the_o womb_n which_o also_o the_o pleasure_n of_o coition_n sometime_o do_v for_o the_o like_a reason_n and_o will_v be_v much_o more_o apt_a to_o cause_v it_o if_o it_o continue_v long_o as_o that_o of_o opium_n do_v note_v the_o inconvenience_n of_o coition_n after_o impregnation_n this_o be_v the_o great_a cause_n that_o whore_n be_v not_o apt_a to_o bear_v child_n because_o frequency_n of_o pleasure_n do_v over-relax_a the_o collum_n 〈◊〉_d 6._o it_o prevent_v abortion_n when_o fear_n terror_n or_o any_o contract_a cause_n as_o grief_n grievous_a passion_n or_o sensation_n do_v threaten_v it_o by_o its_o take_n off_o the_o contraction_n and_o grievance_n that_o cause_v it_o 7_o intumescence_n of_o the_o lip_n be_v from_o their_o relaxation_n admit_v the_o blood_n and_o humour_n into_o they_o in_o a_o plentiful_a manner_n beside_o that_o their_o laxity_n and_o the_o inadvertency_n occasion_v by_o the_o divert_v pleasure_n or_o drowsiness_n that_o follow_v let_v the_o low_a lip_n hang_v down_o careless_o as_o be_v usual_a in_o such_o case_n may_v by_o expose_v much_o more_o of_o that_o lip_n which_o be_v most_o concern_v in_o this_o effect_n make_v it_o seem_v large_a as_o a_o hang_a lip_n do_v 8._o it_o may_v cure_v a_o dropsy_n as_o dr._n wâ—llis_n do_v instance_n 1._o by_o cause_v a_o free_a perspiration_n which_o be_v much_o want_v in_o those_o case_n 2._o by_o relax_v the_o pore_n and_o make_v way_n for_o the_o humour_n to_o 〈◊〉_d 3._o by_o cause_v much_o urine_n as_o cantharides_n millepedes_n &c_n &c_n do_v upon_o the_o account_n of_o their_o volatile-salt_n with_o which_o opium_n abound_v 9_o it_o cure_v stupor_n that_o proceed_v from_o contraction_n as_o by_o cold_a etc._n etc._n by_o relax_v all_o part_n 10._o it_o cause_v anxiety_n and_o distress_n by_o the_o rosin_n stick_v and_o teaze_v the_o stomach_n 11._o vomit_n and_o hiccough_n proceed_v from_o the_o same_o cause_n 12._o convulsion_n be_v cause_v by_o the_o same_o rosin_n while_o it_o continual_o urge_v the_o stomach_n to_o grievous_a vomit_n which_o at_o last_o draw_v other_o part_n as_o the_o stomach_n usual_o do_v when_o under_o great_a grievance_n into_o violent_a contraction_n or_o convulsion_n by_o consent_n to_o endeavour_v its_o assistance_n because_o the_o defensive_a contraction_n grow_v very_o high_a by_o the_o almost_o intolerable_a and_o tedious_a grievance_n at_o stomach_n cause_v a_o mighty_a compression_n of_o the_o springy_a animal_n spirit_n by_o which_o mean_v they_o grow_v very_o forcible_a irrequiete_a and_o violent_o springy_a under_o the_o urgency_n of_o a_o enormous_a compressure_n which_o cause_v such_o convulsive_a motion_n note_v that_o such_o a_o violent_a compression_n of_o the_o animal_n spirit_n into_o a_o great_a springiness_n be_v the_o cause_n of_o the_o strength_n of_o convulsive_a motion_n so_o that_o sometime_o a_o strong_a man_n can_v hardly_o hold_v a_o child_n limb_n in_o such_o case_n 13._o syncopes_fw-la leipothymy_n and_o faint_n follow_v when_o the_o sensitive_a soul_n be_v quite_o tire_v and_o overbear_v by_o the_o fatigue_n of_o such_o distress_n vomit_n and_o defensive_a contraction_n to_o reject_v and_o excuss_v the_o say_v adhere_v and_o teaze_v rosin_n yield_v itself_o to_o rest_n and_o let_v we_o go_v the_o reign_v of_o contraction_n as_o be_v fruitless_a and_o no_o long_o endurable_a whereupon_o all_o the_o sensile_a part_n be_v relax_v in_o the_o high_a degree_n they_o thereby_o grow_v unfit_a for_o sensation_n and_o the_o animal_n spirit_n expand_v as_o far_o as_o the_o atmospherical_a compressure_n permit_v they_o so_o that_o they_o grow_v incapable_a to_o convey_v impression_n by_o which_o mean_v sense_n fail_v and_o motion_n also_o for_o the_o same_o reason_n because_o the_o animal_n spirit_n loose_v their_o springy_a endeavour_n for_o want_n of_o a_o sufficient_a compression_n to_o render_v they_o flippant_a for_o the_o purpose_n which_o be_v the_o cause_n as_o in_o sleep_n that_o sense_n
and_o frequent_a erection_n be_v and_o must_v be_v from_o the_o same_o cause_n 17._o nocturnal_a pollution_n be_v necessary_a consequence_n of_o the_o relaxation_n and_o the_o titillation_n cause_v by_o those_o volatile_a salt_n as_o be_v say_v chap._n xxiii_o the_o explication_n of_o the_o effect_n of_o leave_v off_o opium_n after_o a_o long_a and_o lavish_a use_v thereof_o i._o great_a and_o even_o intolerable_a distress_n anxiety_n and_o depression_n of_o spirit_n do_v happen_v 1._o because_o the_o sensitive_a soul_n who_o be_v so_o much_o comfort_v divert_v and_o support_v by_o the_o habitual_a and_o dear_o belove_a pleasure_n that_o opium_n cause_n be_v sudden_o deprive_v thereof_o by_o which_o it_o be_v main_o sustain_v be_v exceed_o disappoint_v and_o cast_v down_o 2._o because_o he_o now_o labour_v under_o the_o sore_a burden_n of_o the_o three_o contraction_n so_o that_o every_o thing_n seem_v and_o be_v real_o more_o grievous_a â—o_o he_o for_o now_o it_o act_v as_o one_o in_o pain_n or_o grief_n and_o every_o thing_n affect_v he_o more_o smart_o proportionable_a to_o the_o compression_n cause_v thereby_o of_o the_o animal_n spirit_n unless_o he_o return_v to_o the_o pleasure_n of_o opium_n which_o elevate_v it_o again_o or_o use_v generous_a wine_n as_o its_o substitute_n though_o it_o do_v not_o equal_v it_o either_o in_o the_o intenseness_n or_o duration_n of_o the_o pleasure_n unless_o repeat_v as_o i_o have_v some_o where_o direct_v once_o in_o half_a a_o hour_n or_o a_o hour_n in_o a_o moderate_a manner_n which_o cause_v a_o continuance_n of_o the_o pleasure_n though_o it_o can_v equal_v the_o intenseness_n of_o that_o of_o opium_n which_o therefore_o have_v the_o great_a effect_n ii_o a_o return_n of_o all_o disease_n pain_n and_o disaster_n must_v happen_v general_o because_o the_o opium_n take_v they_o off_o by_o a_o bare_a diversion_n of_o the_o sense_n thereof_o by_o pleasure_n iii_o dangerous_a looseness_n happen_v sometime_o because_o the_o sensation_n grow_v more_o grievous_a for_o as_o the_o pleasant_a sensation_n cause_v by_o opium_n take_v away_o the_o perception_n of_o the_o irritation_n of_o humour_n so_o the_o grievance_n of_o lose_v that_o pleasure_n cause_v contraction_n make_v all_o sensation_n smart_a and_o consequent_o more_o irritate_v so_o that_o the_o humour_n have_v thereby_o more_o of_o the_o effect_n of_o purger_n which_o operate_v as_o all_o agree_v by_o irritation_n beside_o that_o the_o humour_n before_o detain_v and_o suspend_v by_o relaxation_n as_o in_o sleep_n be_v now_o therefore_o pour_v down_o in_o great_a quantity_n by_o the_o advance_a contraction_n squeese_v they_o out_o as_o the_o return_n of_o the_o vigilative_a contraction_n after_o sleep_n cause_n man_n to_o be_v more_o apt_a to_o go_v to_o stool_n upon_o awake_v or_o get_v up_o in_o the_o morning_n which_o may_v be_v well_o compare_v in_o some_o measure_n to_o purge_v after_o leave_v off_o the_o use_n of_o opium_n since_o it_o relax_n as_o sleep_n do_v and_o that_o for_o a_o much_o long_a time_n by_o a_o continue_a use_n thereof_o iv_o death_n common_o follow_v for_o all_o the_o reason_n aforesaid_a especial_o the_o great_a and_o intolerable_a distress_n of_o soul_n that_o they_o be_v under_o unless_o opium_n be_v use_v which_o soon_o set_v they_o right_o or_o wine_n its_o substitute_n so_o frequent_o use_v as_o to_o continue_v its_o cordial_a pleasure_n at_o stomach_n nothing_o now_o remain_v but_o to_o take_v a_o short_a review_n to_o see_v whether_o i_o have_v explain_v all_o the_o amaze_a contradiction_n that_o seem_v to_o be_v in_o the_o effect_n of_o opium_n for_o though_o it_o be_v real_o do_v yet_o may_v it_o not_o so_o well_o appear_v as_o when_o set_v one_o against_o the_o other_o it_o will_v be_v tautology_n to_o repeat_v all_o the_o reason_n therefore_o i_o shall_v only_o mention_v they_o in_o the_o close_a order_n i_o at_o first_o enumerate_v they_o that_o you_o may_v see_v that_o they_o be_v all_o explicate_v in_o the_o former_a discourse_n you_o may_v well_o remember_v that_o i_o have_v show_v 1._o how_o it_o cause_v sleep_v and_o watch_v in_o divers_a person_n 2._o how_o it_o cause_v and_o prevent_v sweat_n 3._o how_o it_o relax_n and_o stop_n looseness_n even_o by_o relax_v 4._o how_o it_o stop_v flux_n and_o promote_v sweat_v and_o perspiration_n 5._o how_o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v it_o 6._o how_o it_o cause_v stupidity_n if_o you_o sit_v or_o lie_v still_o otherwise_o promptitude_n in_o business_n 7._o how_o it_o cause_v cloudiness_n and_o serenity_n that_o if_o one_o lie_v still_o and_o doze_n this_o if_o he_o keep_v in_o action_n that_o by_o a_o excessive_a and_o lavish_a use_v thereof_o which_o cause_v moapishness_n this_o by_o a_o temperate_a occasional_a take_v thereof_o especial_o in_o the_o morning_n upon_o journey_n etc._n etc._n 8._o how_o it_o excite_v the_o spirit_n yet_o quiet_v and_o compose_v they_o in_o hysterick_n fit_v diary_n fever_n from_o pain_n commotion_n etc._n etc._n 9_o how_o that_o it_o be_v very_o hot_a and_o take_v of_o fever_n 10._o how_o though_o it_o be_v hot_a and_o bitter_a yet_o it_o lessen_v appetite_n and_o hunger_n which_o be_v a_o grievous_a sensation_n by_o cause_v a_o pleasant_a one_o 11._o how_o it_o sometime_o stop_v urine_n by_o relax_v the_o bladder_n suspending_a humour_n etc._n etc._n and_o promote_v it_o by_o its_o tickle_a volatile_a salt_n as_o cantharides_n bee_n aunt_n etc._n etc._n do_v 12._o how_o it_o relax_n and_o thereby_o weaken_v as_o in_o sleep_n etc._n etc._n yet_o enable_v to_o perform_v labour_n journey_n etc._n etc._n with_o great_a euphory_n by_o divertive_a pleasure_n 13._o how_o it_o cause_v and_o prevent_v abortion_n that_o by_o over-relaxing_a this_o by_o allay_a pain_n terror_n etc._n etc._n that_o may_v cause_v it_o 14._o how_o it_o stop_v vomit_v by_o take_v off_o irritation_n etc._n etc._n and_o cause_v it_o by_o the_o adherence_n of_o its_o indigestible_a and_o viscid_a rosin_n 15._o how_o it_o stop_v purge_v and_o sometime_o cause_v it_o by_o the_o dissolution_n of_o its_o rosin_n by_o a_o strong_a digestion_n fix_a salt_n etc._n etc._n when_o its_o quantity_n be_v considerable_a which_o make_v it_o happen_v but_o rare_o 16._o how_o though_o acrimonious_a it_o take_v away_o the_o sense_n of_o acrimony_n 17._o how_o it_o cause_v madness_n and_o cure_v it_o by_o compose_v the_o spirit_n etc._n etc._n 18._o how_o it_o cause_v palsy_n by_o relax_v the_o part_n and_o make_v they_o susceptible_a of_o humour_n cause_v ill_a digestion_n etc._n etc._n and_o may_v cure_v they_o as_o dr._n willis_n give_v a_o instance_n by_o open_v the_o pore_n 19_o how_o it_o cause_v palsy_n and_o cure_n stupor_n etc._n etc._n that_o proceed_v from_o cold_a and_o contract_n cause_n 20._o how_o it_o cause_v dryness_n in_o the_o mouth_n yet_o by_o take_v off_o fever_n often_o cure_v it_o 21._o how_o it_o take_v off_o hiccough_n and_o cause_v they_o as_o it_o do_v vomit_v and_o for_o the_o same_o cause_n 22._o how_o it_o stanch_v blood_n by_o quiet_v its_o motion_n yet_o promote_v the_o menses_fw-la and_o lochia_n by_o relax_v open_v and_o widen_v the_o vessel_n and_o pore_n 23._o how_o it_o stop_v critical_a motion_n that_o depend_v upon_o irritation_n and_o contraction_n and_o promote_v such_o as_o depend_v upon_o open_v the_o pore_n 24._o how_o it_o revive_v people_n that_o be_v at_o the_o point_n of_o death_n for_o want_n of_o opium_n or_o by_o violent_a contraction_n and_o convulsion_n and_o be_v fatal_a to_o other_o weak_a person_n 25._o how_o it_o cause_v convulsion_n by_o its_o grieve_v rosin_n and_o cure_v they_o by_o quiet_v and_o compose_v the_o spirit_n by_o please_v they_o 26._o how_o it_o cause_v contraction_n by_o the_o grievous_a sensation_n that_o its_o rosin_n cause_n and_o relaxation_n by_o the_o pleasant_a sensation_n that_o its_o salvolatile_a oleosum_fw-la cause_n by_o that_o it_o cause_v many_o ill_a effect_n not_o here_o name_v and_o by_o this_o it_o cure_v they_o for_o how_o can_v such_o contrary_a cause_n according_a as_o one_o or_o the_o other_o prevail_v not_o cause_v contrary_a and_o seem_o contradictory_n effect_n at_o divers_a time_n and_o in_o divers_a person_n 27._o how_o it_o relax_n yet_o cause_v the_o tension_n rigidity_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n by_o its_o titillation_n thus_o have_v you_o all_o even_o the_o most_o mysterious_a and_o seem_o contradictory_n effect_n of_o opium_n explain_v and_o reconcile_v and_o that_o so_o easy_o that_o if_o there_o be_v no_o other_o proof_n of_o the_o truth_n of_o my_o foundation_n it_o be_v sufficient_a to_o convince_v any_o man_n of_o its_o validity_n consider_v the_o vastness_n of_o the_o number_n and_o perplexity_n of_o the_o nature_n of_o those_o effect_n that_o be_v all_o with_o such_o facility_n explain_v be_v able_a even_o
that_o when_o people_n be_v in_o a_o untoward_a condition_n or_o as_o they_o call_v it_o out_o of_o sod_n the_o next_o day_n after_o drink_v man_n often_o advise_v take_v the_o hair_n of_o the_o same_o dog_n that_o be_v drink_v some_o of_o the_o same_o wine_n or_o liquor_n it_o be_v best_o for_o they_o to_o use_v it_o as_o i_o just_a now_o direct_v for_o their_o case_n upon_o the_o good_a effect_n of_o the_o wine_n cease_v be_v much_o like_a that_o upon_o the_o go_n off_o of_o the_o operation_n of_o opium_n which_o may_v also_o in_o this_o case_n be_v use_v instead_o of_o wine_n to_o procure_v a_o better_a and_o blither_n condition_n for_o that_o day_n that_o use_v to_o be_v very_o troublesome_a to_o drinker_n 3._o note_v that_o good_a preparation_n of_o opium_n may_v be_v convenient_o use_v to_o horse_n to_o prevent_v their_o be_v tire_v or_o take_v off_o their_o weariness_n and_o cause_v they_o to_o go_v on_o but_o i_o will_v not_o advise_v any_o preparation_n in_o this_o case_n but_o the_o liquid_a panacea_fw-la in_o good_a ale_n or_o beer_n and_o that_o only_a in_o the_o same_o quantity_n as_o be_v use_v to_o man_n till_o far_a experience_n embolden_v the_o practice_n by_o such_o mean_n i_o can_v doubt_v it_o any_o jade_n may_v be_v make_v to_o appear_v lively_a go_v well_o etc._n etc._n chap._n xxxii_o of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o compose_v the_o sensitive_a soul_n spirit_n etc._n etc._n i_o have_v show_v how_o and_o why_o it_o compose_v and_o quiet_v the_o sensitive_a soul_n spirit_n blood_n stomach_n etc._n etc._n and_o by_o that_o mean_n allay_v all_o the_o fury_n commotion_n perturbation_n and_o turbulent_a exorbitance_n thereof_o and_o that_o often_o without_o sleep_n but_o much_o better_a with_o it_o it_o follow_v therefore_o 1._o that_o it_o prevent_v and_o take_v off_o all_o fret_n and_o turbulent_a passion_n of_o the_o sensitive_a soul_n as_o anger_n uneasy_a agitation_n and_o toss_v of_o the_o mind_n peevishness_n fretfulness_n discontent_n disquietude_n dissatisfaction_n murmur_n turmoiling_n and_o vexatious_a thought_n anxiety_n solicitude_n etc._n etc._n and_o all_o the_o evil_a effect_n thereof_o as_o watch_n waste_v of_o spirit_n or_o strength_n lossitude_n hypochondriacal_a melancholy_n cachexy_n scurvy_n etc._n etc._n but_o these_o last_o belong_v most_o proper_o to_o its_o alterative_a faculty_n or_o virtue_n 2._o all_o involuntary_a furious_a agitation_n of_o the_o sensitive_a soul_n and_o spirit_n as_o madness_n more_o especial_o melancholy_a madness_n or_o such_o as_o proceed_v from_o grievous_a thought_n or_o apprehension_n loss_n cross_n despair_n fear_n terror_n or_o the_o like_a but_o they_o be_v not_o so_o good_a in_o merry_a madness_n as_o those_o from_o joy_n venereal_a fury_n and_o suchlike_a which_o answer_v the_o great_a dispute_n about_o opiate_n in_o madness_n delirium_n epileptical_a fit_n convulsion_n general_a and_o particular_a as_o those_o of_o the_o head_n rise_v of_o the_o light_n vomit_n hiccough_n sabbing_n kecking_n convulsive_a asthma_n palpitation_n and_o tremble_n of_o the_o heart_n shake_v and_o shivering_n upon_o fear_n terror_n cold_a pain_n ague-fits_a convulsive_a colick_n hysterick_n fit_v iliack_a passion_n etc._n etc._n 3._o all_o fever_n and_o fret_n of_o humour_n that_o happen_v from_o any_o of_o the_o aforesaid_a cause_n or_o from_o any_o violent_a motion_n voluntary_a or_o involuntary_a as_o labour_n run_v hew_v fight_a or_o any_o vehement_a exercise_n ratling_n toss_n concussion_n in_o coach_n wagon_n boat_n in_o stormy_a wether_n violent_a ride_v etc._n etc._n or_o from_o heat_n of_o fire_n sun_n bath_n hothouse_n bagnio_n crowd_n lie_v too_o many_o in_o one_o bed_n or_o with_o too_o much_o clothes_n or_o from_o grievous_a sensation_n irritation_n or_o pain_n as_o fever_n upon_o inflammation_n abscess_n bubo_n stone_n colic_n cardialgia_n wound_n fracture_n dislocation_n confusion_n amputation_n lithotomy_n paracentesis_n or_o any_o painful_a operation_n of_o the_o noble_a art_n of_o chirurgery_n agony_n or_o pain_n of_o the_o smallpox_n as_o its_o second_o fever_n and_o the_o like_a or_o from_o flux_n as_o tedious_a and_o turbulent_a vomit_n diarrheas_n dysentery_n cholera_n iliack_a passion_n artificial_a purge_v and_o all_o symptomatick_a or_o immaterial_a fever_n whatsoever_o which_o either_o never_o have_v any_o matter_n but_o proceed_v from_o such_o agitate_a cause_n as_o i_o mention_v or_o remain_v as_o some_o do_v after_o the_o grieve_v matter_n be_v carry_v off_o by_o vomit_v purge_v etc._n etc._n i_o forbear_v mention_v pleurisy_n and_o peripneumonia_n among_o the_o fever_n that_o it_o prevent_v or_o take_v off_o because_o there_o be_v great_a dispute_n whether_o opiate_n be_v convenient_a in_o those_o case_n which_o i_o hope_v to_o determine_v unless_o it_o be_v when_o the_o say_v distemper_n be_v come_v to_o that_o pass_n that_o it_o be_v dangerous_a to_o cause_v sleep_n or_o take_v away_o any_o of_o the_o sense_n of_o the_o irritation_n of_o the_o matter_n to_o be_v expectorate_v lest_o it_o shall_v be_v too_o much_o amass_v in_o the_o bronchias_n or_o windpipe_n and_o so_o choke_v the_o person_n i_o see_v no_o cause_n to_o forbid_v they_o any_o more_o than_o sleep_v or_o opiate_n in_o other_o inflammation_n wherein_o they_o be_v high_o beneficial_a to_o give_v ease_n cause_n sleep_n compose_v the_o spirit_n and_o take_v off_o or_o at_o least_o moderate_a the_o fever_n but_o i_o see_v many_o good_a reason_n to_o use_v they_o 1._o because_o as_o a_o sal-volatile-oleosum_a they_o reserate_v and_o resolve_v clammy_a humour_n and_o be_v so_o agreeable_a in_o principle_n as_o menstraums_n shall_v be_v to_o the_o thing_n to_o be_v resolve_v i_o can_v doubt_v but_o red_a poppy_n be_v upon_o experience_n state_v a_o specific_a in_o those_o case_n for_o that_o reason_n 2._o because_o these_o distemper_n as_o hypocrates_n speak_v be_v from_o a_o segregation_n of_o humour_n by_o agitation_n etc._n etc._n and_o opiate_n excellent_a composer_n thereof_o 3._o because_o they_o be_v such_o great_a discusser_n and_o 4._o open_v the_o pore_n to_o let_v the_o discuss_v matter_n quite_o out_o of_o the_o body_n 5._o because_o it_o may_v be_v that_o by_o its_o relaxation_n upon_o such_o resolution_n the_o lodge_v matter_n may_v be_v cause_v to_o flow_v off_o and_o circulate_v again_o and_o so_o be_v gradue_v discuss_v and_o carry_v off_o by_o the_o open_a pore_n 6._o because_o it_o envigorate_v nature_n to_o perform_v those_o thing_n and_o 7._o give_v ease_n and_o recruit_v of_o the_o spirit_n by_o sleep_n so_o that_o all_o thing_n consider_v i_o think_v as_o experience_n assure_v we_o that_o red_a poppy_n or_o opiate_n in_o due_a quantity_n be_v the_o very_o best_a remedy_n that_o can_v be_v use_v hence_o it_o be_v that_o wedelius_n call_v opium_n a_o antipleuritick_n specific_a he_o have_v observe_v as_o i_o and_o other_o have_v do_v that_o the_o whole_a course_n of_o the_o disease_n and_o expectoration_n will_v succeed_v much_o better_a by_o their_o use._n he_o add_v also_o that_o he_o have_v very_o often_o cure_v they_o by_o its_o help_n without_o let_v of_o blood_n which_o be_v a_o infallible_a sign_n of_o their_o good_a effect_n since_o the_o pleurisy_n can_v hardly_o be_v cure_v without_o bleed_v i_o can_v see_v how_o a_o effect_n that_o bear_v such_o analogy_n to_o sleep_n can_v do_v any_o more_o harm_n than_o sleep_n etmuller_n also_o advise_v the_o give_v of_o opiate_n not_o only_o in_o the_o beginning_n but_o also_o during_o the_o increase_n of_o the_o pleurisy_n or_o peripneumoniae_fw-la so_o that_o i_o conclude_v that_o they_o be_v of_o excellent_a use_n in_o those_o disease_n unless_o it_o be_v when_o sleep_n or_o they_o may_v cause_v too_o much_o insensibleness_n of_o the_o bronchias_n and_o so_o retard_v expectoration_n when_o the_o case_n be_v such_o that_o the_o want_v thereof_o may_v endanger_v the_o person_n be_v be_v choke_v we_o have_v also_o many_o history_n of_o person_n cure_v in_o other_o fever_n by_o large_a dose_n of_o opiate_n i_o suppose_v that_o resinous_a opiate_n cause_v vomit_v and_o great_a disturbance_n by_o reason_n of_o ill_a digestion_n in_o those_o case_n may_v be_v one_o great_a cause_n of_o people_n fear_n and_o jeolousy_n in_o give_v opiate_n which_o be_v easy_o prevent_v by_o give_v liquid_a opiate_n void_a of_o any_o resinous_a particle_n as_o the_o liquid_a panacea_fw-la etc._n etc._n 4._o it_o do_v by_o compose_v quiet_v and_o appease_v the_o motion_n and_o perturbation_n of_o the_o blood_n conduce_v much_o to_o the_o stop_n of_o its_o efflux_n in_o hemorrhage_n or_o bleeding_n that_o be_v unnatural_a as_o at_o nose_n in_o spit_v and_o vomit_v of_o blood_n bleed_v at_o the_o hemorrhoid_v in_o dysentery_n piss_v of_o blood_n etc._n etc._n and_o sometime_o in_o profuse_a menses_fw-la when_o they_o happen_v from_o a_o fever_n or_o too_o much_o motion_n of_o the_o blood_n and_o
benefit_n as_o in_o many_o of_o the_o former_a to_o be_v short_a it_o be_v good_a and_o useful_a in_o all_o pain_n and_o grievous_a sensation_n 1._o eecept_n all_o such_o as_o tend_v to_o the_o speedy_a and_o timely_a benefit_n of_o person_n as_o those_o in_a woman_n labour_n grievance_n at_o stomach_n that_o cause_n vomit_v upon_o over-repletion_n or_o by_o reason_n of_o somewhat_o that_o grieve_v and_o be_v not_o convenient_a to_o stay_v at_o stomach_n or_o irritation_n to_o expectorate_v when_o much_o want_v as_o happen_v sometime_o in_o vomicas_fw-la pleurisy_n peripneumonias_n etc._n etc._n or_o such_o as_o irritate_fw-la and_o solicit_v to_o make_v water_n go_v to_o stool_n etc._n etc._n when_o evacuation_n of_o urine_n ordure_n ill_a humour_n etc._n etc._n be_v requisite_a 2._o except_o when_o grievous_a sensation_n be_v necessary_a call_n or_o intimation_n for_o supply_v refreshment_n etc._n etc._n as_o hunger_n thirst_v etc._n etc._n which_o shall_v be_v take_v off_o only_o by_o the_o pleasure_n of_o good_a meat_n and_o drink_v lest_o nature_n be_v defraud_v where_o you_o may_v observe_v a_o inconvenience_n that_o may_v happen_v by_o the_o frequent_a use_n of_o opium_n take_v away_o appetite_n without_o nutriment_n though_o this_o be_v much_o compensated_a by_o the_o relaxation_n and_o recruit_v that_o opiate_n give_v and_o their_o moderate_v the_o expense_n of_o spirit_n by_o take_v of_o contraction_n and_o may_v more_o if_o not_o whole_o by_o a_o regular_a and_o constant_a way_n of_o eat_v and_o drink_v temperate_o at_o usual_a time_n though_o the_o hunger_n may_v not_o by_o reason_n of_o the_o opiate_n be_v so_o great_a as_o at_o other_o time_n i._o the_o form_n be_v indifferent_a and_o to_o be_v order_v only_o according_a to_o the_o general_a rule_n remember_v that_o the_o liquid_a be_v best_a for_o speed_n ii_o the_o dose_n must_v be_v proportion_v to_o the_o pain_n or_o grievous_a sensation_n and_o always_o rather_o more_o than_o when_o there_o be_v no_o pain_n because_o its_o contraction_n oppose_v the_o relaxation_n to_o be_v induce_v by_o the_o opiate_n observe_v this_o method_n first_o give_v a_o good_a do_v then_o stay_v about_o 2_o or_o 3_o hour_n and_o if_o the_o pain_n be_v not_o at_o all_o lessen_v you_o may_v safe_o then_o give_v half_a the_o quantity_n again_o and_o afterward_o about_o a_o three_o part_n of_o the_o do_v every_o 2_o or_o 3_o hour_n till_o it_o begin_v to_o abate_v but_o upon_o the_o least_o sensible_a abatement_n you_o must_v forbear_v to_o give_v any_o more_o because_o that_o which_o do_v in_o some_o measure_n abate_v the_o pain_n do_v in_o the_o same_o proportion_n abate_v the_o contraction_n and_o consequent_o it_o have_v less_o to_o contest_v with_o therefore_o will_v be_v sure_a to_o conquer_v it_o for_o the_o same_o power_n that_o can_v subdue_v ten_o in_o some_o measure_n will_v subdue_v nine_o in_o a_o great_a measure_n and_o eight_o more_o easy_o than_o nine_o etc._n etc._n till_o the_o pain_n quite_o cease_v whereas_o if_o you_o add_v more_o power_n to_o the_o opiate_n it_o may_v be_v too_o much_o especial_o when_o the_o pain_n be_v thereby_o conquer_v and_o that_o it_o have_v no_o contraction_n to_o contest_v with_o for_o than_o it_o will_v be_v as_o if_o a_o great_a do_v be_v give_v to_o one_o that_o have_v no_o pain_n but_o if_o the_o pain_n increase_v again_o you_o may_v safe_o repeat_v the_o half_n do_v etc._n etc._n every_o 2_o or_o 3_o hour_n till_o it_o again_o begin_v to_o abate_v and_o no_o long_o which_o you_o have_v better_o observe_v to_o do_v as_o soon_o as_o ever_o the_o pain_n begin_v to_o return_v because_o it_o take_v some_o time_n to_o operate_v it_o sollow_v then_o that_o the_o liquid_a form_n be_v most_o convenient_a in_o this_o case_n for_o expedition_n my_o particular_a and_o effectual_a manner_n of_o use_v it_o in_o the_o gout_n will_v be_v somewhat_o too_o redious_a to_o be_v set_v down_o therefore_o since_o it_o may_v be_v obvious_a enough_o to_o the_o sagacious_a that_o consider_v what_o have_v be_v say_v and_o the_o nature_n of_o the_o distemper_n i_o will_v pass_v that_o by_o at_o this_o time_n iii_o the_o vehicle_n in_o cold_a stomach_n and_o constitution_n may_v be_v a_o glass_n of_o wine_n or_o some_o temperate_a cordial_n but_o in_o hot_a case_n or_o where_o a_o fever_n be_v fear_v emulsion_n milk_n and_o water_n or_o water_n alone_o or_o other_o acceptable_a cool_a thing_n or_o such_o as_o be_v direct_v in_o the_o case_n of_o procure_v relaxation_n in_o the_o last_o chapter_n because_o it_o be_v relaxation_n that_o take_v away_o pain_n as_o have_v be_v mechanical_o demonstrate_v but_o heâ—e_v there_o be_v no_o need_n of_o be_v scrupulous_a as_o to_o the_o vehicle_n unless_o it_o be_v in_o respect_n of_o heat_n and_o cold_a as_o the_o case_n happen_v iv_o the_o time_n may_v be_v any_o hour_n as_o the_o case_n require_v only_o remember_v that_o sleep_n conduce_v much_o to_o relaxation_n and_o therefore_o to_o the_o take_v away_o of_o pain_n v._o the_o regimen_n to_o be_v use_v in_o the_o case_n of_o relax_v in_o the_o last_o chapter_n will_v suffice_v but_o it_o be_v convenient_a as_o be_v say_v to_o regard_v the_o stomach_n and_o hot_a and_o cold_a constitution_n especial_o where_o there_o be_v any_o fear_n of_o fever_n by_o give_v cool_a liquid_n as_o emulsion_n etc._n etc._n and_o avoid_v hot_a or_o solid_a thing_n especial_o such_o as_o be_v hard_a of_o digestion_n as_o flâ—sh_v fish_n egg_n etc._n etc._n 1._o note_v that_o it_o be_v very_o advisable_v not_o to_o defer_v the_o use_n of_o opiate_n too_o long_o till_o people_n be_v very_o weak_a though_o it_o may_v seem_v that_o they_o will_v hinder_v some_o due_a evacuation_n for_o i_o can_v see_v what_o harm_n a_o refreshment_n by_o they_o may_v do_v any_o more_o than_o by_o sleep_n both_o depend_v upon_o the_o same_o cause_n viz._n relaxation_n it_o be_v true_a that_o by_o reason_n of_o sleep_n or_o a_o opiate_n the_o evacuation_n may_v be_v a_o little_a defer_v what_o then_o will_v any_o man_n deny_v sleep_n for_o that_o reason_n why_o then_o shall_v a_o physician_n deny_v a_o opiate_n to_o cause_v it_o respite_n nature_n and_o enable_v it_o to_o bear_v its_o burden_n or_o engage_v with_o difficulty_n the_o better_a 2._o remember_v always_o that_o sleep_n be_v a_o great_a help_n to_o take_v away_o pain_n and_o so_o be_v all_o thing_n that_o conduce_v to_o relaxation_n or_o pleasant_a diversion_n 3._o use_v means_n in_o pain_n of_o the_o hemorrhoid_v furdament_n or_o intestinum_fw-la rectum_fw-la and_o indeed_o in_o any_o pain_n within_o the_o gut_n unless_o it_o proceed_v from_o a_o looseness_n that_o opiate_n may_v not_o bind_v man_n too_o much_o as_o leâ—itives_n internal_o or_o emollient_a 〈◊〉_d or_o which_o of_o they_o may_v be_v most_o easy_o and_o convenient_o do_v and_o most_o to_o the_o purpose_n chap._n xxxv_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o cause_n sleep_n it_o primary_o cause_n sleep_v by_o relax_v and_o compose_v quiet_v soothe_v please_a and_o lull_v the_o sensitive_a soul_n and_o spirit_n it_o always_o relax_n but_o do_v not_o always_o sufficient_o compose_v or_o quiet_v the_o spirit_n to_o cause_n sleep_n to_o which_o both_o be_v requisite_a secundary_o by_o take_v away_o grievous_a passion_n or_o sensation_n when_o they_o happen_v to_o hinder_v it_o 1._o as_o soporiserous_a it_o be_v of_o incomparable_a use_n in_o all_o troublesome_a watch_n whether_o they_o be_v from_o grievous_a passion_n or_o sensation_n or_o irrequiete_a motion_n of_o the_o spirit_n though_o not_o so_o certain_a in_o this_o last_o case_n as_o in_o the_o former_a and_o therefore_o prove_v sometime_o unsuccessful_a in_o some_o person_n and_o in_o some_o sort_n of_o madness_n as_o the_o merry_a or_o furicus_n though_o it_o be_v effectual_a in_o melancholy_n and_o slow_a manias_fw-la as_o have_v be_v intimate_v for_o bare_a relaxation_n suffice_v in_o the_o two_o first_o case_n where_o sleep_n be_v hinder_v by_o contraction_n which_o it_o never_o fail_v to_o take_v off_o if_o give_v in_o a_o due_a quantity_n as_o have_v be_v direct_v 2._o to_o recruit_v the_o spirit_n as_o when_o people_n be_v tire_v with_o labour_n journey_n disease_n conflict_n of_o nature_n as_o by_o convulsion_n vomit_n purge_n hysteric_a fit_n and_o the_o like_a 3._o to_o relax_v compose_v take_v away_o pain_n moderate_a flux_n that_o depend_v upon_o grievous_a sensation_n or_o irritation_n and_o its_o consequent_a contraction_n or_o from_o motion_n or_o segregation_n of_o humour_n 4._o to_o promote_v flux_n that_o depend_v upon_o relaxation_n as_o perspiration_n sweat_v as_o also_o the_o menses_fw-la and_o lochia_n in_o some_o case_n of_o all_o which_o you_o have_v particular_a chapter_n which_o see_v i._o the_o form_n may_v be_v indifferent_o either_o solid_a or_o liquid_a as_o
it_o be_v best_o like_v and_o most_o suitable_a to_o people_n mind_n palate_n etc._n etc._n ii_o the_o do_v moderate_a except_o it_o be_v 1._o where_o some_o by_o accident_n require_v otherwise_o as_o pain_n looseness_n vomit_n and_o to_o titillate_v the_o venereal_a membrane_n because_o remote_a which_o see_v in_o the_o respective_a chapter_n of_o the_o use_n of_o opiate_n in_o those_o case_n 2._o where_o the_o general_a rule_n direct_v otherwise_o as_o in_o the_o soft_a flesh_a people_n child_n woman_n etc._n etc._n where_o the_o do_v must_v be_v less_o iii_o the_o vehicle_n must_v be_v the_o same_o as_o be_v direct_v to_o compose_v but_o in_o old_a people_n it_o be_v observe_v that_o smooth_a spirituous_a thing_n as_o good_a ale_n etc._n etc._n conduce_v very_o much_o to_o cause_v sleep_n because_o sulphur_n do_v qualifie-the_a volatile_a salt_n of_o the_o opium_n as_o be_v show_v iv_o the_o time_n in_o general_n be_v at_o the_o due_a distance_n before_o bedtime_n that_o be_v direct_v in_o the_o general_a rule_n but_o opiate_n may_v be_v give_v at_o any_o time_n when_o the_o case_n require_v as_o in_o the_o smallpox_n about_o 12_o 1_o or_o 2_o in_o the_o afternoon_n according_a as_o the_o â—tions_n which_o happen_v in_o the_o afternoon_n or_o towards_o the_o evening_n do_v seize_v they_o and_o in_o ague_n at_o the_o due_a distance_n before_o the_o paroxysm_n invade_v they_o 〈◊〉_d that_o the_o operation_n thereof_o may_v be_v fall_n and_o complete_a before_o the_o time_n that_o the_o fit_n be_v to_o begin_v and_o so_o in_o all_o other_o câ—ses_n of_o the_o like_a â—ind_n v._o the_o regimen_n in_o this_o 〈◊〉_d 〈◊〉_d 〈◊〉_d twosold_a aspect_n 1._o to_o promote_v 〈◊〉_d 2._o to_o compose_v and_o quiet_a motion_n 〈◊〉_d â—tions_n of_o the_o spirit_n 〈◊〉_d etc._n etc._n 〈◊〉_d 〈◊〉_d quiet_v be_v the_o two_o 〈◊〉_d 〈◊〉_d as_o to_o the_o first_o the_o regimen_n must_v be_v the_o same_o as_o be_v direct_v in_o the_o chapter_n of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o relax_v but_o as_o to_o compose_v and_o quiet_v the_o spirit_n i_o shall_v add_v somewhat_o though_o relaxer_n be_v general_o good_a for_o this_o purpose_n unless_o join_v with_o some_o agitate_v accident_n as_o heat_n or_o the_o like_a 1._o as_o to_o diet_n it_o shall_v consist_v of_o cool_a incrassate_a inviscate_a thing_n that_o be_v not_o aromatic_a acid_a or_o saline_a such_o be_v milk-meat_n emulsion_n almond_n milks_n chicken_n broth_n with_o cool_a herb_n water-gruel_n fresh_a and_o young_a soft_a flesh_n lettuce_n purstane_n spinage_n herb_n mercury_n mallow_n and_o such_o like_a mucilage_n as_o of_o quince_n fleabane_n etc._n etc._n the_o drink_n may_v be_v milk_n and_o water_n whey_n or_o such_o unfermented_a liquor_n or_o smooth_a small_a beer_n not_o too_o old_a for_o all_o stale_a drink_n be_v naught_o water_n where_o it_o agree_v etc._n etc._n 2._o rest_v of_o body_n and_o spirit_n must_v be_v contrive_v by_o all_o mean_n as_o by_o lean_v lie_a or_o sit_v still_o without_o any_o motion_n after_o it_o be_v take_v till_o bedtime_n and_o therefore_o let_v the_o person_n if_o the_o season_n permit_v be_v as_o much_o undress_v as_o may_v be_v in_o a_o loose_a garment_n or_o morning-gown_n all_o that_o time_n and_o be_v help_v off_o with_o his_o clothes_n that_o he_o may_v not_o agitate_v his_o body_n when_o sleepy_a and_o not_o before_o let_v he_o go_v into_o a_o cold_a bed_n in_o summer_n and_o but_o a_o little_a warm_v in_o winter_n and_o only_o have_v what_o bedclothe_n suffice_v and_o please_v he_o best_o and_o then_o lie_v absolute_o still_o without_o noise_n light_z or_o fire_n in_o the_o room_n 3._o rest_v and_o tranquillity_n of_o mind_n be_v very_o necessary_a which_o shall_v be_v not_o only_o free_a from_o grievous_a passion_n but_o from_o all_o excess_n of_o joyous_a one_o which_o too_o much_o agitate_v the_o spirit_n 4._o the_o air_n shall_v be_v moist_a and_o moderate_a and_o if_o not_o such_o by_o the_o wether_n render_v so_o by_o art_n especial_o in_o fever_n 5._o all_o evacuation_n shall_v be_v make_v that_o may_v any_o way_n disturb_v his_o sleep_n before_o he_o betake_v himself_o to_o it_o nor_o shall_v the_o stomach_n be_v over-full_a or_o empty_a lest_o any_o grievance_n may_v be_v thereby_o create_v 6._o emollient_a tepid_a bath_n fomentation_n feetwash_n etc._n etc._n do_v fine_o dispose_v people_n to_o sleep_n but_o take_v care_n they_o be_v not_o too_o hot_a for_o heat_n cause_v a_o stir_n of_o blood_n and_o spirit_n which_o be_v a_o enemy_n to_o sleep_n 1._o note_v that_o long_o sleep_v after_o great_a fatigue_n or_o long_o watch_v ought_v not_o to_o be_v very_o frightful_a if_o the_o do_v be_v moderate_a and_o that_o the_o person_n take_v sustenance_n 2._o note_v that_o old_a or_o dry_a person_n or_o such_o as_o be_v very_o unapt_a to_o sleep_v after_o opiate_n be_v often_o cause_v to_o sleep_v by_o smooth_a wine_n ale_z cowslip_n wine_n or_o the_o like_a because_o the_o gentle_a oiliness_n of_o such_o liquor_n do_v correct_v the_o acrimony_n of_o their_o volatile_a salt_n and_o at_o the_o same_o time_n cause_n a_o sense_n of_o pleasure_n which_o relax_n and_o cause_n sleep_v it_o have_v be_v observe_v that_o even_o ambergrise_v and_o musk_n which_o exagitate_v the_o blood_n and_o spirit_n cause_v old_a man_n to_o sleep_n which_o happen_v by_o their_o fine_a sulphur_n ready_o fasten_v upon_o the_o acrimonious_a volatile_a salt_n as_o spirit_n of_o wine_n do_v upon_o sal_fw-la ammoniac_a which_o be_v mix_v do_v soon_o coagulate_v therefore_o i_o be_o apt_a to_o think_v that_o camphire_n will_v be_v of_o excellent_a use_n to_o correct_v the_o opium_n and_o the_o volatile_a salt_n of_o the_o body_n in_o such_o case_n because_o it_o be_v experimental_o certain_a that_o it_o correct_v the_o acrimony_n of_o urine_n of_o semen_n virile_a cantharides_n etc._n etc._n 3._o note_v that_o the_o dry_a the_o body_n be_v the_o more_o unapt_a be_v opiate_n to_o cause_n sleep_n therefore_o dry_a body_n as_o of_o old_a man_n hectical_a person_n etc._n etc._n shall_v be_v well_o moisten_v by_o incrassative_a moistener_n as_o emulsion_n and_o such_o thing_n as_o be_v above_o mention_v and_o order_v in_o the_o chapter_n of_o the_o relax_a use_n of_o opiate_n from_o what_o be_v say_v i_o do_v conclude_v that_o opiate_n do_v cause_n sleep_v very_o ready_o where_o the_o oily_a part_n abound_v and_o that_o thing_n that_o have_v a_o fine_a oleous_a sulphur_n be_v very_o good_a corrector_n of_o it_o where_o acrimonious_a volatile_a salt_n abound_v in_o order_n to_o cause_n sleep_n and_o that_o hence_o it_o be_v that_o some_o ancient_a people_n will_v often_o sleep_v better_o by_o the_o use_n of_o the_o aforementioned_a smooth_a ferment_v sulphureous_a liquor_n than_o by_o the_o use_n of_o opium_n from_o all_o which_o it_o appear_v that_o sleep_n be_v not_o such_o a_o property_n of_o opium_n as_o people_n make_v it_o to_o be_v because_o that_o beside_o relax_v sleep_v also_o require_v a_o great_a rest_n of_o the_o spirit_n and_o the_o sensitive_a soul_n it_o seem_v very_o probable_a from_o the_o premise_n that_o anodyne_n sulphur_n of_o vitriol_n will_v be_v excellent_a to_o cause_v old_a man_n to_o sleep_n for_o it_o doubtless_o cause_n sleep_v only_o by_o obtund_v and_o qualify_a our_o volatile_a salt_n as_o white_a 〈◊〉_d and_o other_o balsamicks_n will_v often_o do_v chap._n xxxvi_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o stop_v flux_n it_o palliate_v moderate_v and_o stop_v flux_n 1._o by_o take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o cause_n contraction_n to_o squeeze_v they_o out_o and_o promote_v their_o motion_n 2._o because_o it_o compose_v and_o still_v the_o motion_n of_o humour_n by_o the_o relaxation_n and_o the_o sleep_n that_o it_o cause_n which_o quiet_v motion_n 3._o because_o thereby_o and_o by_o its_o combine_a agreeableness_n and_o texture_n it_o congregate_n the_o disgregated_a humour_n 4._o because_o the_o relaxation_n suspend_v the_o humour_n 5._o because_o it_o discuss_n ill_a humour_n 6._o because_o the_o pore_n be_v open_v by_o the_o relaxation_n the_o humour_n that_o cause_v the_o flux_n be_v gradual_o perspire_v by_o that_o most_o natural_a and_o universal_a sort_n of_o evacuation_n for_o it_o be_v plain_a reason_n and_o common_a observation_n that_o a_o plentiful_a evacuation_n at_o pore_n stop_v flux_n per_fw-la anum_fw-la etc._n etc._n and_o if_o it_o continue_v perfect_o cure_v they_o ☞_o hence_o it_o be_v that_o the_o use_v of_o opiate_n continue_v do_v happy_o not_o only_o palliate_v but_o perfect_o cure_v diarrheas_n dysentery_n defluxion_n catarrh_n etc._n etc._n it_o therefore_o follow_v that_o it_o be_v of_o great_a use_n 1._o to_o palliate_v moderate_a or_o cure_v all_o flux_n that_o proceed_v from_o irritation_n of_o humour_n as_o vomit_n
the_o pleasure_n yet_o be_v neither_o discover_v for_o many_o thousand_o of_o year_n especial_o consider_v also_o that_o in_o the_o case_n of_o opium_n thousand_o of_o ingenious_a man_n have_v diligent_o inquire_v after_o the_o cause_n of_o its_o operation_n who_o make_v no_o far_a step_n in_o it_o then_o to_o state_n thing_n that_o have_v not_o as_o much_o as_o existence_n viz._n a_o cold_a quality_n and_o 〈◊〉_d fly_v from_o the_o stomach_n to_o the_o head_n to_o be_v the_o cause_n thereof_o therefore_o it_o be_v plain_a that_o neither_o be_v he_o that_o plant_n any_o thing_n neither_o he_o that_o water_v but_o god_n that_o give_v the_o increase_n of_o knowledge_n and_o of_o other_o thing_n to_o who_o be_v all_o glory_n chap._n xx._n the_o explication_n of_o the_o effect_n of_o the_o declination_n of_o the_o operation_n of_o opium_n in_o a_o moderate_a do_v 1._o a_o general_n return_v of_o all_o disease_n and_o disaster_n when_o the_o operation_n of_o opium_n be_v over_o because_o it_o do_v not_o as_o be_v show_v operate_v as_o a_o alterative_a but_o a_o please_a diverter_n of_o the_o sensitive_a soul_n for_o some_o time_n during_o which_o it_o cause_v a_o general_a relaxation_n of_o all_o the_o sensile_a part_n whereby_o the_o animal_n spirit_n be_v expanded_a grow_v unfit_a to_o convey_v impression_n smart_o which_o be_v requisite_a to_o cause_v a_o sense_n of_o pain_n etc._n etc._n as_o have_v be_v often_o say_v but_o it_o cure_v several_a distemper_n viz._n such_o as_o please_v and_o comfort_v the_o sensitive_a soul_n compose_v the_o spirit_n relaxation_n perspiration_n sweat_v etc._n etc._n can_v quite_o take_v away_o of_o which_o more_o particular_o when_o we_o come_v to_o speak_v of_o the_o use_n of_o opium_n in_o cure_n 2._o sweat_n happen_v in_o the_o declination_n of_o its_o operation_n as_o sir_n theodore_n mayern_n myself_o and_o other_o have_v observe_v because_o that_o now_o all_o the_o parâ—s_a contract_n which_o by_o their_o relaxation_n suspend_v all_o humour_n during_o its_o operation_n do_v mechanical_o squeeze_v out_o the_o congest_a humour_n there_o be_v less_o room_n in_o the_o body_n as_o be_v say_v of_o sweat_n upon_o awake_v by_o the_o return_n of_o the_o vigilative_a contraction_n after_o relaxation_n during_o the_o sleep_n which_o be_v to_o be_v compare_v to_o the_o relaxation_n during_o the_o operation_n of_o opium_n and_o the_o return_v of_o the_o contraction_n when_o it_o be_v end_v beside_o that_o both_o upon_o the_o go_v off_o of_o the_o operation_n and_o awake_v the_o motion_n of_o the_o heart_n grow_v more_o vigorous_a as_o it_o do_v upon_o motion_n by_o the_o intentive_a contraction_n do_v more_o powerful_o propell_v the_o humour_n out_o at_o the_o pore_n as_o happen_v in_o sweat_n upon_o motion_n 3._o frequent_v make_v of_o water_n happen_v partly_o by_o the_o titillation_n of_o the_o volatile_a salt_n as_o by_o cantharides_n etc._n etc._n that_o be_v now_o separate_v from_o the_o blood_n partly_o by_o the_o contraction_n of_o the_o whole_a body_n squeese_v it_o out_o at_o the_o kidney_n as_o when_o people_n be_v cold_a they_o make_v more_o water_n for_o that_o reason_n 4._o a_o looseness_n may_v and_o do_v happen_v sometime_o from_o the_o like_a contraction_n squeese_v out_o the_o humour_n that_o be_v suspend_v during_o the_o relaxation_n by_o the_o opium_n which_o be_v common_a for_o such_o contraction_n to_o cause_n as_o by_o cold_a terror_n etc._n etc._n and_o because_o sensation_n grow_v more_o nice_a and_o irritable_a by_o the_o humour_n by_o reason_n of_o the_o contraction_n which_o be_v the_o more_o for_o the_o grievance_n of_o fail_v of_o the_o pleasure_n of_o opium_n therefore_o 5._o disease_n pain_n etc._n etc._n seem_v worse_o upon_o the_o return_n of_o the_o grievance_n because_o of_o the_o great_a ease_n they_o have_v during_o the_o operation_n of_o the_o opium_n contraria_fw-la inter_fw-la se_fw-la magis_fw-la elucescunt_fw-la and_o it_o be_v particular_o observe_v of_o pleasure_n that_o it_o leave_v man_n worse_o than_o it_o find_v they_o thus_o a_o man_n be_v worse_a more_o sad_a etc._n etc._n post_fw-la coitum_fw-la more_o melancholy_a after_o all_o sort_n of_o pleasure_n insomuch_o that_o it_o be_v grow_v to_o a_o proverb_n viz._n after_o merry_a come_v sorry_a or_o after_o mirth_n come_v sorrow_n as_o also_o minus_n gaudebis_fw-la minus_fw-la dolebis_fw-la therefore_o 6._o melaneholy_n do_v often_o if_o not_o always_o happen_v in_o some_o degree_n after_o its_o operation_n be_v end_v 1._o because_o of_o the_o return_n of_o the_o contraction_n or_o toil_n of_o the_o sensitive_a soul_n 2._o because_o as_o be_v say_v the_o sense_n of_o pleasure_n new_o lose_v aggravate_v the_o sorrow_n as_o have_v be_v show_v after_o coition_n etc._n etc._n 7._o the_o pulse_n be_v narrow_a because_o the_o contraction_n return_v with_o melancholy_a and_o return_v of_o disaster_n improve_v when_o that_o so_o happen_v as_o it_o general_o do_v 8._o itch_a of_o the_o skin_n happen_v about_o this_o time_n because_o that_o now_o the_o volatile_a salt_n which_o cause_v tuillation_n be_v arrive_v as_o far_o as_o the_o skin_n upon_o its_o march_n out_o of_o the_o body_n chap._n xxi_o the_o explication_n of_o the_o effect_n of_o opium_n in_o a_o excessive_a do_v the_o cause_n of_o most_o of_o these_o effect_n will_v be_v evident_a from_o the_o explication_n of_o the_o former_a because_o the_o difference_n be_v only_o in_o the_o quantity_n of_o the_o opium_n therefore_o i_o be_o often_o necessitate_v to_o speak_v much_o the_o same_o as_o i_o have_v do_v before_o you_o can_v expect_v any_o good_a effect_n from_o its_o excess_n any_o more_o than_o you_o have_v from_o wine_n though_o the_o best_a of_o cordial_n next_o to_o the_o sal._n volatile_a oleosum_fw-la of_o opium_n but_o rather_o less_o because_o opium_n be_v join_v to_o a_o pernicious_a rosin_n which_o you_o may_v be_v sure_o will_v be_v very_o grievous_a to_o the_o stomach_n in_o great_a quantity_n if_o it_o be_v so_o in_o little_a the_o evil_a effect_n in_o this_o case_n do_v main_o proceed_v either_o from_o too_o much_o relaxation_n as_o in_o drunkenness_n or_o from_o the_o rosin_n at_o stomach_n 1._o a_o heat_n at_o stomach_n be_v cause_v by_o the_o intense_a heat_n of_o the_o opium_n in_o a_o great_a quantity_n it_o be_v sensible_o a_o very_a hot_a thing_n 2._o the_o sense_n of_o weight_n at_o stomach_n be_v cause_v by_o the_o great_a relaxation_n that_o it_o cause_n which_o render_v the_o stomach_n proportionable_o weak_a and_o unable_a to_o endeavour_v its_o own_o relief_n so_o that_o the_o rosin_n etc._n etc._n lie_v heavy_a upon_o it_o thus_o we_o find_v a_o great_a heaviness_n at_o stomach_n when_o any_o thing_n grieve_v it_o that_o it_o can_v reject_v or_o discharge_v 3._o gaity_n of_o humour_n be_v cause_v at_o first_o as_o by_o the_o pleasure_n of_o a_o great_a quantity_n of_o wine_n by_o its_o please_a agreeableness_n to_o the_o membrane_n at_o stomach_n till_o the_o relaxation_n grow_v enormous_a as_o by_o a_o great_a do_v of_o wine_n sudden_o drink_v to_o which_o it_o be_v very_o like_a in_o all_o its_o effect_n except_o such_o as_o proceed_v from_o the_o rosin_n stick_v at_o stomach_n which_o wine_n have_v not_o 4._o sardonick_a laughter_n be_v cause_v as_o you_o see_v in_o drunken_a people_n when_o they_o be_v disable_v by_o the_o great_a relaxation_n that_o they_o can_v well_o express_v themselves_o by_o the_o fail_a tongue_n they_o endeavour_v it_o by_o a_o silly_a kind_n of_o feign_a or_o make_v laughter_n as_o they_o call_v it_o while_o the_o please_a titillation_n at_o stomach_n much_o incline_v they_o to_o mirth_n if_o they_o know_v how_o to_o manage_v and_o carry_v it_o on_o 5._o laxity_n and_o consequent_o debility_n of_o all_o part_n be_v cause_v by_o the_o extraordinary_a relaxation_n of_o they_o by_o a_o continual_a and_o permanent_a sense_n of_o pleasure_n which_o happen_v considerable_o in_o the_o momentary_a pleasure_n of_o venus_n much_o more_o in_o this_o continual_a and_o last_a pleasure_n when_o a_o great_a do_v make_v it_o intense_a as_o in_o drunkenness_n 6._o alienation_n of_o the_o mind_n be_v cause_v as_o in_o drunkenness_n by_o a_o over_o relaxation_n of_o the_o brain_n and_o its_o membrane_n 7._o loss_n of_o memory_n happen_v by_o the_o same_o mean_n as_o in_o drunkenness_n so_o 8._o darkness_n of_o eye_n be_v cause_v by_o a_o relaxation_n of_o the_o coat_n and_o membrane_n of_o the_o eye_n but_o main_o by_o the_o expansion_n of_o the_o animal_n spirit_n by_o that_o relaxation_n which_o as_o in_o sleep_n render_v they_o unfit_a to_o convey_v the_o impression_n of_o light_n etc._n etc._n 9_o laxity_n of_o the_o cornea_n be_v from_o the_o same_o relaxation_n 10._o appearance_n of_o various_a colour_n happen_v by_o as_o be_v say_v the_o unevenness_n of_o the_o cornea_n etc._n etc._n when_o so_o relax_v whereas_o when_o it_o be_v due_o