of_o the_o muscle_n of_o the_o gut_n stomach_n tendon_n membrane_n and_o the_o like_a fibrose_n part_n natural_o resist_v distraction_n and_o have_v a_o power_n of_o contract_v themselves_o after_o extension_n yea_o more_o we_o see_v that_o all_o fibres_fw-fr even_o in_o their_o natural_a posture_n be_v somewhat_o upon_o the_o stretch_n for_o when_o they_o be_v cut_v they_o instant_o shorten_v themselves_o towards_o both_o end_n which_o will_v not_o happen_v if_o they_o have_v be_v constitute_v in_o a_o middle_a state_n betwixt_o laxity_n and_o extension_n as_o a_o bow_n unbend_v be_v quiet_a suffer_v neither_o contraction_n nor_o distraction_n of_o its_o part_n now_o if_o all_o fibre_n even_o in_o their_o natural_a state_n suffer_v some_o degree_n of_o stretch_v certain_o when_o the_o artery_n be_v replenish_v with_o blood_n their_o cavity_n must_v be_v dilate_v and_o in_o the_o dilatation_n of_o their_o cavity_n their_o transverse_n or_o circular_a fibre_n must_v suffer_v much_o more_o stretch_v than_o they_o do_v before_o and_o because_o to_o this_o dilatation_n of_o the_o artery_n a_o constriction_n immediate_o succeed_v which_o be_v not_o possible_a to_o be_v effect_v without_o a_o abbreviation_n of_o the_o circular_a fibres_fw-fr of_o the_o artery_n and_o because_o that_o abbreviation_n or_o contraction_n be_v connatural_a to_o the_o fibre_n themselves_o therefore_o it_o be_v impossible_a that_o the_o artery_n after_o that_o violent_a stretch_v cause_v by_o their_o repletion_n and_o turgency_n shall_v not_o exercise_v by_o natural_a necessity_n that_o mechanic_a power_n they_o have_v of_o contract_v themselves_o by_o virtue_n of_o their_o circular_a fibre_n gird_v they_o inward_a and_o equal_o impossible_a that_o the_o artery_n shall_v so_o contract_v themselves_o without_o expel_v at_o the_o same_o time_n out_o of_o their_o orifice_n the_o blood_n that_o dilate_a they_o whence_o it_o appear_v beyond_o dispute_n that_o the_o spontaneous_a constriction_n of_o the_o distend_v artery_n be_v the_o cause_n of_o the_o expulsion_n of_o the_o blood_n out_o of_o they_o into_o the_o substance_n of_o the_o part_n contrary_a to_o their_o opinion_n who_o ascribe_v this_o expulsion_n only_o to_o the_o systole_n of_o the_o heart_n ¶_o ⸪_o the_o natural_a method_n of_o acquire_a science_n you_o know_v be_v to_o begin_v from_o thing_n more_o know_v and_o then_o to_o advance_v to_o thing_n less_o know_v to_o proceed_v from_o effect_n to_o their_o cause_n see_v therefore_o that_o we_o be_v now_o certain_a that_o the_o blood_n in_o animal_n be_v carry_v by_o a_o perpetual_a circular_a motion_n through_o all_o part_n of_o the_o body_n our_o next_o business_n be_v to_o inquire_v what_o be_v the_o cause_n of_o this_o admirable_a motion_n as_o well_o the_o final_a as_o the_o efficient_a i_o begin_v from_o the_o final_a it_o be_v a_o question_n worthy_a our_o consideration_n why_o or_o to_o what_o end_n nature_n all_o who_o counsel_n and_o action_n be_v ordain_v by_o a_o infinite_a wisdom_n have_v institute_v this_o rapid_a circulation_n of_o the_o blood_n constant_a it_o be_v even_o from_o common_a experience_n that_o whenever_o the_o blood_n be_v quiet_a or_o cease_v from_o motion_n whether_o within_o or_o without_o the_o body_n of_o a_o animal_n the_o red_a and_o grumose_n part_v of_o it_o soon_o curdle_n and_o be_v separate_v from_o the_o serose_n or_o albumen_n and_o so_o the_o constitution_n or_o contexture_n of_o it_o be_v dissolve_v and_o corrupt_v whereas_o on_o the_o contrary_a while_o the_o blood_n continue_v in_o perpetual_a motion_n within_o its_o vessel_n in_o the_o body_n of_o a_o live_a animal_n so_o long_o the_o ordinate_a mixture_n of_o its_o element_n due_a temper_n and_o vital_a constitution_n of_o it_o be_v conserve_v for_o mechanical_a reason_n in_o our_o ensue_a discourse_n to_o be_v explain_v it_o seem_v then_o that_o such_o a_o mixture_n of_o the_o constituent_a part_n of_o the_o blood_n upon_o which_o the_o vitality_n of_o it_o do_v necessary_o depend_v can_v be_v otherwise_o conserve_v than_o by_o a_o continual_a agitation_n and_o concussion_n make_v in_o the_o vessel_n first_o by_o the_o heart_n with_o strong_a force_n impel_v the_o blood_n through_o the_o artery_n then_o that_o impulsive_a force_n languish_v by_o filtration_n in_o the_o space_n intermediate_v betwixt_o the_o artery_n and_o vein_n next_o in_o the_o vein_n by_o the_o constriction_n of_o their_o circular_a fibre_n by_o the_o compression_n of_o the_o muscle_n and_o the_o viscera_n and_o the_o inspire_a air_n all_o which_o compression_n will_v not_o suffice_v be_v not_o valve_n place_v commodious_o within_o the_o vein_n by_o which_o the_o motion_n of_o the_o blood_n be_v accelerate_a and_o a_o far_a conquassation_n of_o it_o make_v and_o here_o we_o meet_v with_o a_o fair_a occasion_n to_o reflect_v upon_o the_o mutual_a anastomôse_n of_o the_o capillary_a vein_n and_o the_o infrequent_a distribution_n of_o valve_n in_o one_o and_o the_o same_o vein_n for_o both_o these_o contribute_v also_o their_o proportion_n towards_o the_o end_n now_o under_o our_o disquisition_n for_o the_o texture_n of_o the_o vein_n be_v indeed_o lax_n and_o soft_a yet_o such_o as_o may_v by_o virtue_n of_o their_o circular_a fibre_n be_v constringe_v and_o contract_v hence_o it_o be_v that_o by_o the_o blood_n regurgitate_v in_o those_o tract_n of_o the_o vein_n that_o have_v no_o valve_n by_o the_o great_a quantity_n and_o force_n of_o its_o regurgitation_n or_o recoil_n the_o low_a part_n of_o the_o vein_n be_v much_o dilate_v and_o on_o the_o contrary_a the_o high_a part_n be_v contract_v so_o that_o the_o blood_n be_v by_o this_o reflux_n though_o inobservable_a agitate_a and_o conquassated_a may_v revive_v its_o due_a commistion_n and_o conserve_v its_o vital_a constitution_n it_o appear_v then_o the_o defect_n of_o valve_n also_o have_v its_o use_n within_o the_o cavity_n of_o the_o artery_n as_o i_o say_v before_o no_o valve_n be_v place_v because_o the_o grand_a force_n by_o which_o the_o blood_n be_v impel_v through_o they_o be_v more_o than_o sufficient_a to_o conquassate_fw-it and_o commix_v it_o by_o wedge_v in_o as_o it_o be_v the_o more_o fluid_a albugineous_a particle_n among_o the_o red_a grumose_n particle_n that_o from_o both_o sort_n commix_v per_fw-la minimas_fw-la moleculas_fw-la as_o they_o say_v and_o yet_o mutual_o reluctant_a the_o vital_a mication_n or_o oscillatory_n intestine_a motion_n of_o the_o blood_n may_v be_v continue_v so_o then_o here_o be_v neither_o need_n of_o nor_o place_n for_o a_o fermentation_n now_o from_o the_o consideration_n of_o these_o thing_n premise_v i_o conclude_v that_o the_o circulation_n of_o the_o blood_n be_v institute_v for_o the_o conservation_n of_o its_o requisite_a temper_n and_o vital_a constitution_n which_o be_v to_o be_v inquire_v and_o which_o lead_v we_o to_o the_o admirable_a effect_n and_o benefit_n arise_v to_o the_o animal_n oeconomy_n from_o the_o same_o velocity_n of_o the_o circulation_n of_o the_o blood_n which_o be_v certain_o so_o great_a that_o the_o whole_a mass_n of_o blood_n run_v its_o circular_a race_n in_o the_o twenty_o part_n of_o a_o hour_n or_o thereabouts_o even_o in_o a_o sedentary_a and_o sedate_v man_n as_o have_v by_o many_o be_v demonstrate_v from_o the_o quantity_n of_o blood_n common_o contain_v in_o the_o body_n from_o the_o number_n of_o pulse_n make_v in_o a_o hour_n and_o from_o the_o quantity_n of_o blood_n express_v by_o every_o pulse_n of_o the_o heart_n and_o we_o have_v already_o see_v what_o advantage_n redound_v to_o the_o blood_n itself_o from_o this_o velocity_n our_o curiosity_n spur_v we_o on_o to_o inquire_v also_o what_o other_o scope_n or_o end_n nature_n may_v probable_o be_v conceive_v to_o have_v propose_v to_o herself_o when_o she_o institute_v this_o so_o rapid_a motion_n or_o what_o emolument_n and_o benefit_n from_o thence_o redound_v to_o the_o oeconomy_n of_o the_o whole_a body_n of_o these_o the_o first_o seem_v to_o be_v this_o that_o in_o every_o pulsation_n of_o the_o heart_n a_o great_a quantity_n of_o blood_n be_v effuse_v and_o protrude_v out_o of_o the_o capillary_a artery_n into_o the_o habit_n of_o the_o part_n for_o their_o refocillation_n by_o influent_a life_n of_o which_o i_o have_v former_o discourse_v copiose_o in_o this_o place_n for_o by_o how_o much_o swift_a the_o motion_n of_o any_o liquor_n or_o other_o fluid_a through_o a_o pipe_n or_o canal_n be_v so_o much_o a_o great_a quantity_n of_o it_o be_v in_o equal_a time_n effuse_v at_o the_o orifice_n thereof_o as_o have_v be_v ingenious_o demonstrate_v by_o b._n castellus_n fluxu_fw-la and_o therefore_o the_o blood_n be_v like_o a_o full_a and_o rapid_a torrent_n impel_v into_o the_o pore_n of_o the_o flesh_n and_o viscera_n the_o second_o be_v the_o energy_n of_o the_o stroke_n with_o which_o the_o blood_n project_v by_o the_o heart_n dash_v against_o the_o same_o extreme_a part_n which_o energy_n be_v
the_o muscle_n of_o the_o heart_n be_v compose_v of_o the_o same_o constituent_a part_n with_o all_o other_o muscle_n viz._n of_o bundle_n of_o carnose_n fibres_n of_o the_o same_o tendinose_n and_o contrahible_a substance_n of_o the_o same_o prismatic_a figure_n in_o the_o same_o manner_n dispose_v layer_n upon_o layer_n bind_v down_o by_o mutual_a contexture_n in_o the_o same_o manner_n intersperse_v with_o branch_n of_o nerve_n fasten_v to_o tendon_n and_o enliven_v by_o blood_n irrigate_a they_o out_o of_o the_o artery_n in_o a_o word_n there_o be_v no_o sensible_a difference_n or_o disparity_n the_o figure_n of_o the_o whole_a heart_n except_v which_o yet_o do_v not_o diversify_v the_o organic_n nature_n of_o it_o no_o more_o than_o the_o diversity_n of_o figure_n among_o other_o muscle_n do_v make_v they_o of_o a_o different_a nature_n then_o if_o we_o consider_v the_o action_n of_o both_o the_o heart_n and_o all_o other_o muscle_n we_o shall_v find_v that_o as_o well_o the_o fibre_n of_o the_o heart_n as_o those_o of_o all_o other_o muscle_n act_v by_o contraction_n of_o themselves_o if_o we_o descend_v to_o the_o immediate_a motive_n cause_n and_o the_o mechanic_n mode_n of_o their_o operate_n from_o what_o we_o have_v already_o say_v it_o be_v manifest_a that_o it_o be_v as_o impossible_a for_o the_o heart_n to_o be_v inflate_v and_o move_v by_o a_o incorporeal_a faculty_n or_o by_o spirit_n or_o by_o the_o blood_n alone_o however_o violent_o rush_v into_o it_o or_o by_o the_o same_o blood_n to_o what_o degree_n soever_o rarify_v in_o its_o ventricles_n or_o by_o a_o fermentation_n conflict_n and_o displosion_n of_o acid_n and_o saline_n juice_n meet_v together_o in_o the_o heart_n as_o it_o be_v for_o the_o muscle_n of_o the_o limb_n to_o be_v regular_o move_v by_o the_o same_o cause_n it_o remain_v therefore_o that_o as_o all_o other_o muscle_n be_v move_v by_o contraction_n of_o their_o fibre_n the_o pore_n of_o they_o be_v fill_v and_o distend_v so_o also_o it_o be_v most_o probable_a that_o the_o proxime_fw-la or_o immediate_a cause_n of_o the_o motion_n i_o mean_v only_o the_o constriction_n of_o the_o heart_n be_v the_o dilatation_n or_o distension_n of_o the_o pore_n of_o its_o fibre_n which_o cause_v their_o abbreviation_n or_o contraction_n i._n e._n the_o systole_n of_o the_o heart_n but_o what_o the_o mediate_v cause_o be_v by_o which_o the_o pore_n of_o the_o fibre_n be_v dilate_v to_o the_o abbreviation_n of_o the_o fibre_n themselves_o we_o shall_v after_o a_o few_o minute_n inquire_v in_o the_o mean_a time_n i_o will_v lay_v down_o this_o other_o proposition_n that_o the_o mediate_v cause_n of_o the_o heart_n motion_n seem_v to_o differ_v from_o that_o by_o which_o the_o muscle_n of_o the_o limb_n be_v incite_v to_o voluntary_a motion_n since_o it_o be_v a_o truth_n know_v to_o all_o man_n that_o we_o can_v move_v what_o muscle_n we_o please_v of_o any_o limb_n and_o continue_v their_o motion_n as_o long_o as_o we_o please_v and_o stop_v it_o when_o we_o please_v but_o the_o motion_n of_o the_o heart_n be_v not_o subject_a to_o the_o empire_n of_o our_o will_n but_z like_o that_o of_o a_o mill_n perpetual_a whether_o we_o sleep_v or_o wake_v and_o since_o even_o without_o our_o knowledge_n or_o perception_n the_o heart_n as_o agitate_a by_o a_o certain_a natural_a necessity_n make_v most_o vehement_a and_o almost_o momentany_a stroke_n or_o jerk_n alternate_o short_a and_o isochronical_a or_o equal_o temporaneous_a pause_n interpose_v betwixt_o they_o nor_o ever_o either_o much_o vary_v that_o constant_a rhythm_n of_o its_o pulse_n while_o we_o be_v in_o the_o state_n of_o health_n or_o intermit_v the_o same_o during_o life_n therefore_o certain_o there_o must_v be_v somewhat_o of_o difference_n between_o the_o mediate_a cause_n of_o the_o heart_n natural_a motion_n on_o one_o part_n and_o the_o mediate_a cause_n of_o the_o voluntary_a motion_n of_o all_o other_o muscle_n on_o the_o other_o beside_o in_o a_o egg_n from_o the_o first_o day_n incubation_n of_o the_o hen_n the_o punctum_fw-la saliens_fw-la and_o then_o the_o vesicula_fw-la pulsans_fw-la exhibit_v to_o our_o sight_n this_o dance_n of_o life_n already_o begin_v when_o we_o can_v conceive_v it_o to_o be_v possible_a that_o there_o shall_v be_v in_o that_o first_o rudiment_n of_o the_o foetus_fw-la any_o sensation_n of_o good_a or_o evil_n any_o will_n to_o pursue_v the_o good_a or_o avoid_v the_o evil_a and_o when_o nothing_o of_o the_o brain_n be_v yet_o form_v nay_o more_o in_o the_o heart_n of_o a_o viper_n take_v out_o of_o the_o body_n and_o put_v into_o warm_a water_n the_o pulsation_n be_v observe_v to_o continue_v many_o hour_n when_o by_o reason_n of_o the_o abscission_n of_o the_o nerve_n all_o commerce_n betwixt_o the_o brain_n and_o the_o heart_n be_v extinct_a no_o sensation_n or_o election_n can_v be_v imagine_v to_o ordain_v and_o command_v that_o motion_n wherefore_o we_o be_v oblige_v to_o confess_v that_o the_o first_o and_o mediate_a cause_n of_o the_o heart_n pulsation_n be_v in_o some_o respect_n or_o other_o divers_a from_o that_o whereby_o the_o other_o muscle_n be_v incite_v to_o motion_n at_o the_o command_n of_o the_o will._n but_o to_o explore_v wherein_o this_o nice_a difference_n may_v most_o probable_o consist_v be_v a_o work_n of_o so_o great_a difficulty_n that_o i_o wish_v it_o be_v possible_a for_o i_o to_o revoke_v the_o temerarious_a promise_n i_o make_v to_o attempt_v it_o nor_o shall_v i_o have_v courage_n enough_o to_o carry_v i_o so_o much_o as_o one_o step_n far_o if_o i_o do_v not_o derive_v it_o whole_o from_o the_o well_o know_a candour_n and_o benignity_n of_o my_o most_o learned_a auditor_n for_o the_o remain_a part_n of_o my_o way_n though_o short_a be_v yet_o dark_a and_o rocky_a with_o precipice_n on_o both_o side_n and_o all_o the_o light_n i_o can_v expect_v must_v be_v from_o a_o few_o spark_n strike_v out_o of_o my_o flinty_a subject_n by_o the_o force_n of_o conjecture_n if_o therefore_o i_o chance_v to_o stumble_v or_o err_v humanity_n will_v oblige_v you_o rather_o to_o put_v forth_o your_o hand_n to_o support_v or_o guide_v i_o than_o to_o deride_v my_o blindness_n in_o hope_n of_o this_o favour_n i_o will_v venture_v to_o proceed_v certain_a it_o be_v that_o the_o first_o and_o mediate_a cause_n of_o the_o motion_n of_o the_o heart_n as_o well_o as_o that_o of_o the_o motion_n of_o the_o other_o muscle_n whatsoever_o it_o shall_v at_o length_n be_v find_v to_o be_v be_v derive_v to_o it_o by_o the_o nerve_n from_o the_o brain_n for_o as_o if_o the_o nerve_n insert_v into_o any_o muscle_n be_v strict_o compress_v by_o a_o ligature_n or_o cut_v off_o the_o power_n of_o motion_n in_o that_o muscle_n be_v present_o intercept_v or_o total_o destroy_v as_o common_a experience_n witness_v so_o if_o the_o nerve_n of_o the_o eight_o conjugation_n be_v either_o strict_o compress_v by_o a_o ligature_n round_o about_o or_o cut_v off_o in_o the_o neck_n of_o any_o animal_n there_o sudden_o will_v ensue_v a_o visible_a change_n in_o the_o motion_n of_o his_o heart_n witness_v the_o memorable_a experiment_n make_v by_o dr._n lower_n and_o record_v in_o his_o excellent_a book_n the_o cord_n 2._o where_o he_o affirm_v that_o the_o heart_n which_o before_o reciprocate_v its_o motion_n moderate_o and_o rhythmical_o present_o after_o the_o ligature_n have_v be_v make_v upon_o the_o say_a nerve_n begin_v to_o palpitate_v and_o tremble_v and_o by_o degree_n grow_v more_o and_o more_o languid_a till_o the_o poor_a creature_n die_v which_o be_v within_o two_o day_n other_o experiment_n confirm_v the_o same_o thing_n i_o may_v allege_v if_o it_o be_v not_o universal_o acknowledge_v by_o anatomist_n that_o the_o motive_n force_n of_o the_o heart_n depend_v upon_o some_o influence_n from_o the_o brain_n and_o among_o these_o one_o of_o the_o most_o accurate_a affirm_v that_o nature_n make_v the_o cerebellum_fw-la as_o a_o storehouse_n of_o animal_n spirit_n chief_o for_o the_o use_n of_o the_o heart_n that_o the_o motion_n of_o it_o may_v be_v perpetual_o maintain_v say_v pro_fw-la motu_fw-la cordis_n praestando_fw-la tam_fw-la sedula_fw-la &_o sollicita_fw-la fuit_fw-la naetura_fw-la ut_fw-la 2._o praeter_fw-la nervorum_fw-la propagines_fw-la ubique_fw-la in_o illud_fw-la densè_fw-la distributas_fw-la pro_fw-la continuo_fw-la spirituum_fw-la animalium_fw-la influxu_fw-la cerebellum_fw-la insuper_fw-la quasi_fw-la perenne_fw-fr corum_fw-la promptuarium_fw-la ei_fw-la accommodaverit_fw-la a_o cujus_fw-la benigna_fw-la &_o constante_n influentia_fw-la adeò_fw-la dependet_fw-la ut_fw-la fi_fw-la spirituum_fw-la influxus_fw-la vel_fw-la minimus_fw-la temporis_fw-la momento_n impediatur_fw-la motus_fw-la ejus_fw-la illicò_fw-la deficiat_fw-la but_o why_o have_v i_o recourse_n to_o the_o authority_n of_o man_n when_o nature_n herself_o in_o her_o constant_a process_n of_o form_v the_o part_n of_o a_o embryon_n seem_v to_o
congruous_a to_o the_o organical_a structure_n of_o the_o heart_n to_o all_o which_o i_o have_v be_v careful_a to_o adjust_a they_o and_o in_o fine_a consistent_a among_o themselves_o then_o i_o shall_v with_o assurance_n conclude_v that_o the_o heart_n be_v as_o all_o automata_n be_v move_v by_o mechanic_n necessity_n which_o be_v what_o i_o propose_v to_o demonstrate_v even_o without_o that_o incredible_a displosion_n of_o saline_n and_o acid_n spirit_n in_o the_o heart_n first_o imagine_v by_o doctor_n willis_n and_o since_o assert_v by_o a_o man_n of_o much_o great_a erudition_n and_o more_o solid_a judgement_n namely_o alphonsus_n borellus_n as_o necessary_a to_o be_v suppose_v in_o order_n to_o the_o solution_n of_o this_o great_a problem_n of_o the_o pulsation_n of_o the_o heart_n and_o that_o of_o the_o motion_n of_o the_o rest_n of_o the_o muscle_n which_o pretty_a conceit_n i_o will_v first_o revive_v in_o your_o memory_n by_o recite_v a_o few_o of_o borellus_n own_o word_n faithful_o and_o then_o offer_v to_o your_o consideration_n the_o reason_n that_o have_v induce_v i_o to_o reject_v it_o restat_fw-la igitur_fw-la say_v he_o quòd_fw-la sicut_fw-la omnes_fw-la musculi_fw-la contrahuntur_fw-la inflatis_fw-la vesiculis_fw-la eorum_fw-la pororum_fw-la sic_fw-la quoque_fw-la immediata_fw-la causa_fw-la tensionis_fw-la cordis_n erit_fw-la inflatio_fw-la vesicularum_fw-la pororum_fw-la ejus_fw-la facta_fw-la à _fw-la fermentativa_fw-la ebullitione_fw-la tartarearum_fw-la partium_fw-la sanguinis_fw-la à _fw-la succo_n spirituoso_fw-la ex_fw-la orificiis_fw-la nervorum_fw-la instillato_fw-la etc._n etc._n the_o reason_n that_o dissuade_v i_o from_o assent_v to_o so_o great_a a_o man_n in_o this_o matter_n be_v these_o first_o we_o have_v the_o testimony_n even_o of_o our_o sight_n the_o most_o certain_a of_o all_o our_o sense_n that_o in_o a_o egg_n after_o a_o day_n or_o two_o incubation_n of_o the_o hen_n the_o punctum_fw-la saliens_fw-la first_fw-mi and_o then_o the_o vesicula_fw-la pulsans_fw-la be_v agitate_a by_o a_o manifest_a pulsation_n in_o the_o centre_n of_o the_o colliquamentum_fw-la or_o genital_a humour_n which_o be_v a_o pure_a and_o homogeneous_a liquor_n even_o before_o any_o the_o least_o sign_n of_o blood_n can_v be_v discern_v here_o therefore_o the_o suppose_a immediate_a cause_n of_o the_o heart_n motion_n viz._n a_o inflation_n from_o a_o fermentative_a ebullition_n of_o the_o tartarous_a part_n of_o the_o blood_n meeting_n and_o conflict_v with_o the_o spirituose_fw-la juice_n instill_a out_o of_o the_o nerve_n into_o the_o heart_n certain_o can_v have_v no_o place_n for_o at_o that_o time_n in_o the_o egg_n neither_o heart_n nor_o brain_n nor_o nerve_n be_v yet_o form_v nor_o be_v any_o part_n of_o the_o colliquamentum_fw-la convert_v into_o blood_n &_o causarum_fw-la in_o rerum_fw-la natura_fw-la nondum_fw-la existentium_fw-la nulli_fw-la dantur_fw-la effectus_fw-la beside_o the_o same_o vesicula_fw-la pulsans_fw-la be_v from_o the_o begin_n of_o the_o change_n of_o the_o genital_a liquor_n into_o blood_n not_o only_o the_o conceptacle_n of_o it_o but_o also_o the_o engine_n that_o give_v it_o motion_n and_o therefore_o the_o new_a make_v blood_n can_v contribute_v nothing_o towards_o the_o pulsation_n thereof_o second_o if_o not_o only_o the_o natural_a motion_n of_o the_o heart_n but_o also_o the_o voluntary_a motion_n of_o the_o rest_n of_o the_o muscle_n proceed_v from_o a_o explosion_n of_o mutual_o hostile_a spirit_n concur_v and_o combat_v in_o they_o as_o borellus_n affirm_v why_o have_v not_o all_o other_o muscle_n as_o well_o as_o the_o heart_n a_o perpetual_a pulsation_n in_o they_o when_o the_o same_o blood_n and_o the_o same_o succus_fw-la spirituosus_fw-la perpetual_o concur_v in_o they_o no_o less_o than_o in_o the_o heart_n and_o what_o dominion_n can_v the_o soul_n have_v over_o the_o muscle_n of_o the_o limb_n to_o exercise_v which_o of_o they_o she_o please_v and_o as_o long_o as_o she_o please_v and_o give_v they_o rest_v when_o she_o please_v if_o they_o be_v agitate_a every_o moment_n by_o squibbs_n or_o cracker_n break_v within_o they_o certain_o she_o can_v never_o moderate_v such_o violent_a and_o tumultuous_fw-la explosion_n beside_o it_o be_v wonderful_a strange_a if_o those_o explosion_n be_v make_v in_o a_o muscle_n when_o it_o act_n that_o we_o shall_v never_o perceive_v it_o to_o be_v distend_v or_o heave_v up_o outward_o but_o that_o on_o the_o contrary_a we_o shall_v plain_o perceive_v the_o muscle_n in_o all_o voluntary_a motion_n to_o be_v strong_o constringe_v inward_o to_o be_v minorate_v and_o become_v hard_a which_o be_v a_o certain_a indicium_fw-la that_o they_o be_v move_v in_o a_o manner_n quite_o contrary_a to_o inflation_n three_o such_o a_o explosion_n make_v in_o the_o heart_n may_v indeed_o cause_v the_o diastole_n of_o it_o by_o inflate_v and_o distend_v the_o ventricles_n but_o will_v hinder_v the_o systole_n or_o constriction_n of_o they_o inward_o which_o be_v requisite_a to_o the_o expression_n of_o the_o blood_n for_o the_o suppose_a explosion_n consist_v like_o that_o of_o aurum_fw-la fulminans_fw-la or_o gunpowder_n in_o a_o motion_n expansive_a will_v of_o necessity_n dilate_v the_o cavity_n of_o the_o heart_n four_o if_o a_o explosion_n of_o acid_n and_o saline_n liquor_n meet_v commix_v and_o war_a in_o the_o heart_n be_v the_o immediate_a efficient_a of_o its_o motion_n it_o be_v consentaneous_a to_o infer_v that_o where_o the_o ingredient_n of_o this_o explosive_a mixture_n be_v more_o copiose_fw-la there_o the_o explosion_n ought_v to_o be_v more_o frequent_a &_o è_fw-la contra_fw-la but_o in_o suck_a infant_n who_o be_v nourish_v only_o with_o milk_n can_v reasonable_o be_v think_v to_o have_v much_o if_o any_o thing_n of_o acidity_n in_o the_o nutritive_a juice_n or_o of_o saltness_n in_o their_o blood_n the_o pulse_n of_o the_o heart_n be_v notwithstanding_o even_o in_o the_o state_n of_o health_n at_o least_o double_o quick_a or_o more_o frequent_a than_o in_o full_a grow_v man_n nay_o such_o who_o delight_n to_o feed_v on_o salt_n meat_n and_o drink_v plentiful_o french_a and_o other_o subacid_a wine_n ergo_fw-la it_o be_v high_o improbable_a that_o the_o pulse_n of_o the_o heart_n shall_v be_v the_o effect_n of_o such_o explosion_n these_o be_v the_o reason_n that_o move_v i_o when_o i_o come_v to_o this_o instable_n bog_n to_o withdraw_v my_o judgement_n from_o the_o conduct_n of_o borellus_n who_o before_o i_o have_v so_o close_o follow_v and_o to_o divert_v into_o a_o private_a way_n which_o seem_v to_o promise_v i_o smother_v and_o firm_a soot_n and_o which_o notwithstanding_o i_o will_v not_o commend_v to_o other_o unless_o your_o approbation_n shall_v encourage_v i_o to_o pave_v it_o meanwhile_o the_o hourglass_n admonish_v i_o to_o reserve_v till_o i_o meet_v with_o some_o other_o opportunity_n what_o may_v be_v far_o allege_v to_o confirm_v the_o precedent_a explication_n of_o the_o efficient_a cause_n of_o the_o systole_n of_o the_o heart_n i_o will_v now_o add_v no_o more_o than_o three_o short_a advertisement_n and_o resign_v you_o up_o to_o the_o more_o profitable_a and_o more_o pleasant_a entertainment_n of_o your_o own_o better_a thought_n the_o first_o be_v that_o be_v probable_a that_o in_o every_o diastole_n of_o the_o heart_n the_o few_o and_o little_a drop_n of_o the_o succus_fw-la nervosus_fw-la which_o by_o wedge_v themselves_o into_o the_o small_a rhomboid_a pore_n or_o mesh_n of_o the_o fibre_n of_o the_o heart_n and_o so_o dilate_v they_o cause_v the_o immediate_o precedent_a systole_n be_v by_o the_o restitutive_a motion_n of_o the_o same_o fibres_fw-fr squeeze_v out_o of_o those_o pore_n into_o the_o parenchyma_n of_o the_o heart_n whence_o they_o be_v absorb_v and_o carry_v off_o with_o the_o blood_n by_o the_o vein_n and_o so_o make_v room_n for_o the_o next_o succeed_a drop_n to_o cause_v the_o next_o systole_n and_o so_o the_o systole_n and_o diastole_n of_o the_o heart_n come_v to_o be_v alternate_o repete_v and_o the_o circulation_n of_o the_o blood_n to_o be_v perpetuate_v this_o i_o say_v be_v probable_a because_o nature_n have_v institute_v the_o like_a absorption_n of_o the_o redundant_fw-la succus_fw-la nervosus_fw-la by_o vein_n in_o many_o other_o part_n of_o the_o body_n more_o eminent_o in_o the_o upper_a part_n of_o the_o neck_n where_o the_o jugular_a vein_n imbibe_n whatever_o humour_n distil_v from_o the_o bottom_n of_o the_o brain_n agit_fw-fr as_o doctor_n lower_v express_o affirm_v and_o with_o good_a reason_n in_o these_o word_n humour_n omnis_fw-la è_fw-la cerebro_fw-la proveniens_fw-la in_o venas_fw-la jugulares_fw-la resorbetur_fw-la i_o have_v heretofore_o i_o confess_v a_o thought_n that_o the_o humour_n contain_v in_o the_o pericardium_n may_v have_v no_o other_o fountain_n but_o the_o relic_n of_o the_o succus_fw-la nervosus_fw-la express_v out_o of_o the_o fibre_n of_o the_o heart_n in_o the_o diastole_n when_o after_o violent_a tension_n they_o exercise_v their_o natural_a faculty_n of_o restitution_n but_o when_o i_o have_v
see_v that_o the_o liquor_n find_v in_o the_o pericardium_n be_v easy_o capable_a of_o coagulation_n either_o by_o heat_n or_o cold_a so_o as_o to_o become_v like_o jelly_n of_o hartshorn_n or_o the_o white_a of_o a_o egg_n harden_v by_o boil_v as_o the_o serum_fw-la of_o the_o blood_n will_v do_v and_o observe_v the_o various_a little_a gland_n seat_v about_o the_o basis_n of_o the_o heart_n for_o which_o i_o can_v find_v no_o other_o equal_o probable_a use_n as_o to_o instil_v the_o serum_fw-la into_o the_o pericardium_n to_o facilitate_v the_o motion_n of_o the_o heart_n which_o most_o certain_o that_o liquor_n do_v as_o the_o humour_n instill_v out_o of_o the_o glandulae_fw-la lacrymale_n upon_o the_o outside_n of_o the_o eye_n serve_v to_o moisten_v and_o make_v they_o more_o easy_o movable_a every_o way_n when_o i_o have_v i_o say_v observe_v and_o consider_v these_o thing_n i_o reject_v that_o thought_n and_o embrace_v this_o of_o the_o absorption_n of_o the_o relic_n of_o the_o succus_fw-la nervosus_fw-la by_o the_o vein_n of_o the_o heart_n the_o second_o be_v that_o the_o diastole_n of_o the_o heart_n be_v cause_v partly_o by_o the_o relaxation_n of_o the_o fibre_n of_o it_o spontaneous_o restore_v themselves_o to_o their_o natural_a posture_n and_o length_n as_o all_o other_o tensile_n body_n be_v wont_a to_o do_v after_o they_o have_v be_v distend_v partly_o by_o the_o force_n of_o the_o blood_n rush_v out_o of_o the_o ear_n into_o the_o ventricles_n of_o the_o heart_n and_o replenish_n they_o wherefore_o the_o wisdom_n of_o nature_n be_v admirable_a also_o in_o this_o that_o she_o ordain_v these_o two_o cause_n of_o the_o diastole_n viz._n the_o relaxation_n of_o the_o fibre_n and_o the_o influx_n of_o the_o blood_n into_o the_o ventricles_n to_o be_v exact_o coincident_a that_o with_o unite_a force_n they_o may_v cooperate_v more_o efficacious_o whence_o it_o appear_v that_o in_o the_o diastole_n the_o heart_n be_v not_o whole_o passive_a as_o all_o anatomist_n hitherto_o have_v believe_v it_o to_o be_v for_o unless_o the_o fibres_n do_v restore_v themselves_o to_o their_o former_a longitude_n which_o be_v a_o natural_a action_n at_o the_o same_o time_n the_o influx_n of_o the_o blood_n happen_v certain_o there_o can_v be_v no_o room_n to_o receive_v the_o blood_n because_o the_o inside_n of_o the_o ventricles_n will_v continue_v to_o touch_v each_o the_o other_o and_o so_o there_o can_v be_v no_o diastole_n the_o three_o and_o last_o be_v that_o it_o appear_v from_o the_o whole_a series_n of_o this_o discourse_n that_o the_o pulsation_n or_o constriction_n of_o the_o heart_n have_v its_o force_n from_o that_o mechanic_n power_n which_o be_v call_v the_o wedge_n and_o that_o the_o blood_n be_v express_v out_o of_o the_o heart_n by_o virtue_n of_o another_o mechanic_n power_n which_o be_v name_v the_o praelum_fw-la or_o press_n and_o consequent_o that_o the_o heart_n itself_o be_v as_o all_o automata_n be_v move_v not_o by_o spirit_n nor_o by_o a_o pulsifick_a faculty_n nor_o by_o rarefaction_n of_o the_o blood_n nor_o ebullition_n or_o fermentation_n of_o the_o blood_n nor_o by_o explosion_n of_o saline_n and_o acid_n spirituose_fw-la liquor_n but_o by_o mechanic_n necessity_n which_o from_o the_o beginning_n i_o hope_v i_o shall_v be_v able_a fair_o to_o prove_v if_o the_o success_n of_o my_o endeavour_n have_v not_o be_v answerable_a to_o that_o hope_n i_o will_v not_o go_v about_o to_o extenuate_v the_o blame_n of_o my_o faileur_n by_o cite_v example_n of_o much_o great_a wit_n which_o have_v before_o i_o in_o vain_a attempt_v to_o reveal_v the_o same_o secret_a of_o nature_n but_o consolate_v myself_o with_o this_o that_o my_o judge_n be_v man_n no_o less_o belove_v for_o their_o exemplary_a candour_n and_o humanity_n than_o honour_v for_o their_o excellency_n in_o all_o kind_n of_o learning_n and_o who_o need_v not_o be_v put_v in_o mind_n that_o truth_n be_v a_o tree_n who_o root_n be_v in_o heaven_n and_o of_o which_o even_o the_o wise_a of_o we_o dim-sighted_a mortal_n here_o upon_o earth_n see_v nothing_o but_o the_o shadow_n of_o its_o branch_n i_o will_v therefore_o conclude_v this_o inelaborate_a disquisition_n with_o that_o memorable_a say_n of_o the_o prince_n of_o roman_a orator_n consolation_n de_n his_o statuat_fw-la unusquisque_fw-la ut_fw-la libet_fw-la quid_fw-la autem_fw-la verius_fw-la sit_fw-la deus_fw-la ipse_fw-la viderit_fw-la hominem_fw-la quidem_fw-la scire_fw-la arbitror_fw-la neminem_fw-la ¶_o ⸫_o my_o lecture_n such_o as_o they_o be_v much_o honour_a auditor_n you_o have_v with_o oblige_a patience_n hear_v be_v please_v i_o beseech_v you_o to_o hear_v also_o before_o you_o rise_v a_o word_n which_o i_o have_v to_o speak_v in_o my_o own_o defence_n be_v it_o not_o indecent_a to_o compare_v small_a thing_n with_o great_a i_o shall_v venture_v perhaps_o to_o advertise_v you_o that_o the_o reason_n which_o induce_v i_o to_o attempt_v a_o reformation_n of_o the_o borellian_a hypothesis_n of_o the_o motion_n of_o the_o heart_n which_o doctor_n harvey_n himself_o call_v the_o sun_n of_o the_o microcosm_n sanguine_a seem_v to_o have_v some_o kind_n of_o analogy_n to_o those_o which_o move_v the_o prince_n of_o astronomer_n tycho_n brahe_n to_o dislike_v the_o ptolemaic_a system_n of_o the_o macrocosm_n or_o great_a world_n and_o to_o excogitate_v a_o new_a one_o of_o more_o probability_n and_o neatness_n for_o as_o tycho_n animadvert_v that_o the_o celestial_a orb_n have_v be_v by_o ptolemy_n distribute_v unhansom_o that_o so_o many_o and_o so_o great_a epicycle_n be_v in_o vain_a imagine_v to_o explicate_v the_o retrogradation_n of_o the_o planet_n and_o their_o various_a respect_n to_o the_o sun_n and_o that_o the_o equality_n of_o the_o circular_a motion_n be_v measure_v not_o from_o the_o centre_n of_o its_o proper_a circle_n as_o it_o ought_v but_o from_o the_o centre_n of_o another_o eccentric_a circle_n against_o the_o first_o principle_n of_o nature_n and_o art_n invent_v a_o new_a system_fw-la exempt_a from_o all_o these_o incommodity_n which_o be_v in_o truth_n the_o copernican_n invert_v so_o i_o conceive_v that_o in_o the_o borellian_a hypothesis_n and_o explosion_n of_o i_o know_v not_o what_o saline_n and_o acid_n material_n in_o the_o heart_n be_v not_o only_o in_o itself_o extreme_o improbable_a and_o incongruous_a to_o the_o wisdom_n of_o nature_n which_o always_o constitute_v certain_a and_o regular_a cause_n to_o produce_v certain_a and_o regular_a effect_n but_o also_o unnecessary_o suppose_v to_o solve_v the_o phaenomenon_n of_o the_o heart_n pulsation_n set_v my_o dull_a brain_n on_o work_n to_o reform_v it_o and_o soon_o invent_v another_o that_o seem_v both_o free_a from_o those_o inconvenience_n and_o more_o agreeable_a to_o the_o organical_a structure_n of_o the_o heart_n to_o which_o above_o all_o thing_n it_o be_v requisite_a i_o shall_v endeavour_v to_o adjust_a it_o this_o i_o think_v myself_o oblige_v to_o signify_v lest_o any_o here_o shall_v believe_v either_o that_o i_o have_v usurp_v to_o myself_o this_o whole_a system_n of_o the_o motion_n of_o the_o heart_n from_o that_o most_o excellent_a mathematician_n alphonsus_n borellus_n who_o memory_n i_o high_o honour_n or_o that_o i_o lay_v claim_n to_o more_o than_o a_o candid_a attempt_n to_o reform_v it_o ¶_o ⸫_o epilogus_fw-la praelectionum_fw-la quidem_fw-la vela_fw-la jam_fw-la tandem_fw-la contraxi_fw-la nondum_fw-la tamen_fw-la dissolutam_fw-la video_fw-la concionem_fw-la resistamus_fw-la igitur_fw-la hîc_fw-la parumper_fw-la auditores_fw-la ornatissimâ—_n si_fw-la vobis_fw-la ita_fw-la videatur_fw-la &_o ad_fw-la stupendam_fw-la illam_fw-la cujus_fw-la rationem_fw-la mechanicam_fw-la hactenus_fw-la tam_fw-la anxiè_fw-la inquisivimus_fw-la cordis_n fabricam_fw-la seriò_fw-la respiciamus_fw-la ind_n enim_fw-la etiamsi_fw-la alia_fw-la omne_fw-la in_o universitate_fw-la rerum_fw-la deessent_fw-la divinae_fw-la architecturae_fw-la documenta_fw-la cuivis_fw-la hominum_fw-la pronum_fw-la est_fw-la infer_v &_o quam_fw-la sit_fw-la immensa_fw-la illius_fw-la caeterorumque_fw-la omnium_fw-la in_o hoc_fw-la mundo_fw-la adspect_n abilium_fw-la conditoris_fw-la solertia_fw-la quámque_fw-la parum_fw-la ab_fw-la immedicabili_fw-la cum_fw-la animi_fw-la tum_fw-la mentis_fw-la stupiditate_fw-la olim_fw-la abfuerit_fw-la epicurus_n qui_fw-la animalia_fw-la casu_fw-la quodam_fw-la in_fw-la prima_fw-la rerum_fw-la procreatione_fw-la genita_fw-la fuisse_fw-la vecorditer_fw-la censuit_fw-la &_o opinatus_fw-la est_fw-la consequenter_fw-la totam_fw-la in_o iis_fw-la membrorum_fw-la varietatem_fw-la dearticulationemque_fw-la non_fw-la aliunde_fw-la quam_fw-la ex_fw-la atomorum_fw-la fortè_fw-la fortuna_fw-la post_fw-la infinitos_fw-la inter_fw-la se_fw-la in_o spatio_fw-la infinito_fw-la vortices_fw-la ita_fw-la concurrentium_fw-la atque_fw-la commistarum_fw-la dispositione_n extitisse_fw-la quamobrem_fw-la neque_fw-la ullam_fw-la fuisse_fw-la intelligentis_fw-la naturae_fw-la prudentiam_fw-la quae_fw-la ossa_fw-la cerebrum_fw-la cor_fw-la nervos_fw-la venas_fw-la quae_fw-la oculos_fw-la manus_fw-la pedes_fw-la viscera_fw-la quae_fw-la cetera_fw-la omne_fw-la conformans_fw-la ad_fw-la fine_n certos_fw-la seu_fw-la functiones_fw-la partibus_fw-la congruas_fw-la respexerit_fw-la sed_fw-la singulas_fw-la part_n ita_fw
march_n 28._o 1683._o ordered_n that_o the_o three_o anatomic_a lecture_n read_v on_o the_o 19_o 20_o and_o 21_o day_n of_o this_o present_a month_n in_o the_o theatre_n of_o his_o majesty_n royal_a college_n of_o physician_n in_o london_n by_o dr._n walter_n charleton_n fellow_n of_o the_o same_o college_n be_v forthwith_o print_v and_o publish_v tho._n cox_n president_n three_o anatomic_a lecture_n concern_v 1._o the_o motion_n of_o the_o blood_n through_o the_o vein_n and_o artery_n 2._o the_o organic_a structure_n of_o the_o heart_n 3._o the_o efficient_a cause_n of_o the_o heart_n pulsation_n read_v on_o the_o 19_o 20_o and_o 21_o day_n of_o march_n 1682_o 3_o in_o the_o anatomic_a theatre_n of_o his_o majesty_n royal_a college_n of_o physician_n in_o london_n by_o walter_n charleton_n m._n d._n and_o fellow_n of_o the_o same_o college_n publish_a by_o command_n of_o the_o most_o learned_a precedent_n london_n print_v for_o walter_n kettilby_n at_o the_o sign_n of_o the_o bishops-head_n in_o st._n paul_n churchyard_n 1683._o praeloquium_fw-la cum_o non_fw-la ita_fw-la pridem_fw-la clarissime_fw-la ornatissiméque_fw-la praeses_fw-la mandatum_fw-la tuum_fw-la ut_fw-la ad_fw-la saxum_fw-la hoc_fw-la anatomicum_fw-la hîc_fw-la denuò_fw-la volvendum_fw-la i_o accingerem_fw-la ad_fw-la obsequium_fw-la paratus_fw-la accepissem_fw-la mox_fw-la apud_fw-la i_o ultrò_fw-la citróque_fw-la agitare_fw-la coepi_fw-la quodnam_fw-la argumenti_fw-la genus_fw-la prae_fw-la caeteris_fw-la mihi_fw-la seligerem_fw-la quo_fw-la &_o excellentiae_fw-la tuus_fw-la expectationi_fw-la aliquatenus_fw-la satisfacere_fw-la possem_fw-la simul_fw-la &_o caeterorum_fw-la è_fw-la doctissimis_fw-la meis_fw-la collegis_fw-la quorum_fw-la hîc_fw-la florem_fw-la video_fw-la tota_fw-la urbe_fw-la delibatum_fw-la auscultationi_fw-la prolixiùs_fw-la gratificari_fw-la plurima_fw-la quidem_fw-la tunc_fw-la temporis_fw-la anxiae_fw-la ac_fw-la in_o diversa_fw-la distractae_fw-la seize_v offerebant_fw-la menti_fw-la nec_fw-la ad_fw-la gratiam_fw-la vulgi_fw-la conciliandam_fw-la fortassis_fw-la incommoda_fw-la sed_fw-la principum_fw-la virorum_fw-la quos_fw-la in_o celeberrimo_fw-la hocce_fw-la theatro_fw-la placidè_fw-la considentes_fw-la venerabundus_fw-la aspicio_fw-la erudita_fw-la curiositate_fw-la prorsus_fw-la indigna_fw-es judicabam_fw-la omne_fw-la tandem_fw-la verò_fw-la animo_fw-la se_fw-la meo_fw-la ingessit_fw-la summum_fw-la illud_fw-la necdum_fw-la etiam_fw-la medicorum_fw-la vulgo_fw-la satis_fw-la intellectum_fw-la naturae_fw-la mysterium_fw-la sanguinis_fw-la nempe_fw-la motus_fw-la circularis_fw-la quo_fw-la de_fw-la quidem_fw-la plerique_fw-la omnes_fw-la passim_fw-la gestiunt_fw-la garrire_n paucos_fw-la tamen_fw-la reperias_fw-la qui_fw-la de_fw-la causis_fw-la ejusdem_fw-la de_fw-la conditionibus_fw-la atque_fw-la circumstantiis_fw-la &_o quod_fw-la caput_fw-la est_fw-la rei_fw-la de_fw-la ratione_fw-la mechanica_fw-la cogitarunt_fw-la unquam_fw-la &_o quod_fw-la seriò_fw-la dolendum_fw-la adhuc_fw-la pauciores_fw-la existunt_fw-la qui_fw-la malè_fw-la se_fw-la habentibus_fw-la consilium_fw-la daturi_fw-la respicere_fw-la soliti_fw-la sint_fw-la ad_fw-la fidissimam_fw-la illam_fw-la morbis_fw-la sive_fw-la acutis_fw-la sive_fw-la chronicis_fw-la medentium_fw-la cynosuram_fw-la his_o ego_fw-la igitur_fw-la adeò_fw-la pudendam_fw-la adeò_fw-la etiam_fw-la valetudine_fw-la adversa_fw-la languentibus_fw-la periculosam_fw-la nunc_fw-la demum_fw-la ut_fw-la excutiam_fw-la incuriam_fw-la utque_fw-la aliquod_fw-la remedium_fw-la illorum_fw-la inscitiae_fw-la adhibeam_n mecum_fw-la statui_fw-la arreptâ_fw-la hâc_fw-la nuper_fw-la demandatae_fw-la mihi_fw-la provinciae_fw-la occasione_n de_fw-fr veris_fw-la hoc_fw-la est_fw-la mechanicis_fw-la causis_fw-la quibus_fw-la in_o orbem_fw-la perpetuò_fw-la sanguis_fw-la movetur_fw-la pro_fw-la ingenioli_fw-it mei_fw-la tenuitate_fw-la inquirere_fw-la affulsit_fw-la quip_n animo_fw-la spei_fw-la scintillula_fw-la quaedam_fw-la ex_fw-la iis_fw-la quae_fw-la ist_fw-mi â_fw-la de_fw-la quaestione_fw-la apud_fw-la vos_fw-la dicenda_fw-la habeo_fw-la lucis_fw-la nonnihil_fw-la afferri_fw-la posse_fw-la ad_fw-la eam_fw-la penitùs_fw-la explicandam_fw-la quamobrem_fw-la ne_fw-la spem_fw-la alnisse_fw-la videar_fw-la inanem_fw-la permissu_fw-la vestro_fw-la primùm_fw-la agam_fw-la de_fw-la sanguinis_fw-la per_fw-la venas_fw-la ad_fw-la cor_fw-la recurrentis_fw-la motu_fw-la rapidissimo_fw-la itemque_fw-la de_fw-la causis_fw-la istius_fw-la tantae_fw-la velocitatis_fw-la deinde_fw-la cordis_n ipsius_fw-la conformationem_fw-la organicam_fw-la perscrutabor_fw-la &_o postremò_fw-la conabor_fw-la causas_fw-la cordis_fw-la pulsationem_fw-la efficientes_fw-la quae_fw-la hactenus_fw-la omnium_fw-la elusisse_fw-la videntur_fw-la anatomicorum_fw-la solertiam_fw-la explorare_fw-la haec_fw-la autem_fw-la dum_fw-la viritìm_fw-la enucleare_fw-la molior_fw-la clarioris_fw-la doctrinae_fw-la gratiâ_fw-la demonstrationes_fw-la aliquot_fw-la mechanicas_fw-la ad_fw-la institutum_fw-la meum_fw-la apprimè_fw-la facientes_fw-la ex_fw-la alphonsi_fw-la borelli_n omnium_fw-la quotquot_fw-la hoc_fw-la saeculo_fw-la nostro_fw-la floruêre_fw-la mathematicorum_fw-la facilè_fw-la solertissimi_fw-la scriptis_fw-la mutuabor_fw-la omittendo_fw-la interea_fw-la caeterorum_fw-la ferè_fw-la omnium_fw-la qui_fw-la post_fw-la harveum_fw-la nostrum_fw-la de_fw-la circuitione_n sanguinis_fw-la conscripserunt_fw-la opiniones_fw-la idque_fw-la ne_fw-la aut_fw-la tempus_fw-la frustrà _fw-la conterere_fw-la aut_fw-la memoriae_fw-la vestrae_fw-la fidelitati_fw-la diffidere_fw-la censear_fw-la habetis_fw-la itaque_fw-la auditores_fw-la aequissimi_fw-la praesentis_fw-la mei_fw-la summam_fw-la consilii_fw-la eorumque_fw-la quae_fw-la dicere_fw-la aggredior_fw-la seriem_fw-la quam_fw-la dum_fw-la ingenii_fw-la toto_fw-la impetu_fw-la persequi_fw-la contendam_fw-la nolo_fw-la existimetis_fw-la i_o mihi_fw-la veritatis_fw-la arbitrium_fw-la arrogare_fw-la semper_fw-la equidem_fw-la verum_fw-la quaero_fw-la quinetiam_fw-la senecae_fw-la illustri_fw-la exemplo_fw-la animatus_fw-la quaero_fw-la sine_fw-la inveniendi_fw-la spe_fw-la tantum_fw-la abest_fw-la ut_fw-la credam_fw-la esse_fw-la i_o aliis_fw-la docendis_fw-la parem_fw-la neque_fw-la etiam_fw-la adeò_fw-la sum_fw-la mihi_fw-la suffenus_n ut_fw-la cujusquam_fw-la expectem_fw-la conatibus_fw-la meis_fw-la applausum_fw-la novi_fw-la enim_fw-la quam_fw-la difficile_fw-la sit_fw-la &_o diligentiae_fw-la laudem_fw-la simul_fw-la &_o gratiam_fw-la celeritatis_fw-la mereri_fw-la caeterùm_fw-la unum_fw-la illud_fw-la i_o solatur_fw-la quòd_fw-la fermè_fw-la rebus_fw-la suâ_fw-la naturâ_fw-la difficillimis_fw-la venia_fw-la sit_fw-la prolixior_fw-la apud_fw-la prudentes_fw-la viros_fw-la quibus_fw-la non_fw-la ignotum_fw-la quam_fw-la sit_fw-la arduum_fw-la novis_fw-la autoritatem_fw-la obscuris_fw-la lucem_fw-la dubiis_fw-la fidem_fw-la afferre_fw-la praelectio_fw-la i._o of_o the_o circular_a motion_n of_o the_o blood_n and_o the_o admirable_a effect_n thereof_o so_o plausible_a and_o favourable_a have_v the_o hypothesis_n of_o various_a ferment_n congenial_a to_o and_o perpetual_o resident_a in_o the_o various_a part_n principal_o in_o the_o viscera_n of_o sanguineous_a and_o more_o perfect_a animal_n seem_v to_o many_o of_o the_o virtuoso_n of_o this_o our_o inquisitive_a age_n that_o they_o have_v not_o doubt_v to_o ascribe_v to_o they_o a_o powerful_a energy_n and_o necessary_a influence_n in_o all_o the_o divers_a motion_n all_o the_o mutation_n all_o the_o concoction_n all_o the_o secretion_n and_o other_o operation_n institute_v by_o nature_n in_o such_o animal_n either_o for_o the_o conservation_n of_o they_o in_o their_o single_a being_n or_o for_o the_o propagation_n of_o their_o respective_a species_n nor_o be_v it_o easy_a for_o we_o to_o name_v any_o particular_a function_n any_o action_n though_o real_o and_o manifest_o organical_a which_o the_o sectator_n of_o this_o hypothesis_n will_v not_o present_o attribute_v to_o some_o peculiar_a ferment_n lurk_v and_o operate_n in_o the_o part_n by_o which_o that_o action_n be_v do_v and_o confer_v forsooth_o somewhat_o of_o efficacy_n towards_o the_o do_n of_o it_o as_o if_o the_o organical_a constitution_n of_o that_o part_n be_v insufficient_a to_o the_o function_n and_o use_n for_o which_o it_o be_v design_v without_o the_o help_n and_o cooperation_n of_o a_o specific_a ferment_n or_o as_o if_o the_o whole_a animal_n oeconomy_n depend_v upon_o no_o other_o harmony_n but_o that_o of_o numerose_n fermentation_n in_o a_o word_n they_o make_v they_o only_o not_o omnipotent_a as_o heraclitus_n the_o ephesian_a dream_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o all_o place_n be_v full_a of_o spirit_n and_o daemon_n heracliti_fw-la that_o preside_v over_o human_a action_n so_o these_o gentleman_n imagine_v all_o the_o part_n of_o animal_n to_o be_v full_a of_o i_o know_v not_o what_o spiritual_a ferment_n that_o by_o occult_a influence_n regulate_v and_o diversify_v their_o function_n and_o this_o comment_n many_o have_v endeavour_v to_o assert_v by_o their_o write_n with_o as_o much_o confidence_n as_o if_o the_o verity_n of_o it_o be_v evident_a either_o from_o cogent_a reason_n or_o by_o autopsy_n when_o in_o truth_n they_o be_v no_o more_o able_a to_o prove_v by_o solid_a argument_n or_o by_o sensible_a demonstration_n the_o existence_n of_o many_o of_o their_o imaginary_a fermentative_a liquor_n or_o spirit_n in_o the_o dissect_a part_n to_o which_o they_o be_v please_v to_o consign_v they_o than_o heraclitus_n be_v able_a to_o exhibit_v to_o man_n sight_n any_o one_o of_o his_o daemon_n i_o say_v many_o of_o their_o imaginary_a ferment_n i_o do_v not_o say_v any_o because_o the_o acid_n phlegm_n find_v in_o the_o stomach_n of_o various_a animal_n may_v perhaps_o so_o far_o emulate_v the_o nature_n of_o a_o ferment_n as_o to_o deserve_v the_o same_o name_n for_o be_v endow_v with_o a_o incisive_a penetrate_a and_o dissolve_v faculty_n it_o be_v not_o improbable_a but_o it_o may_v conduce_v to_o the_o dissolution_n and_o liquation_n of_o
act_v continual_o but_o interrupt_o or_o per_fw-la vice_n short_a and_o almost_o isochronic_a or_o equal_a quiet_n interpose_v so_o that_o the_o blood_n express_v by_o the_o heart_n do_v not_o flow_v thence_o in_o a_o continue_a course_n as_o river_n and_o fountain_n do_v that_o be_v without_o intermission_n carry_v on_o by_o the_o weight_n of_o their_o water_n but_o gush_v forth_o and_o stop_v alternate_o though_o this_o vicissitude_n be_v exact_o regular_a and_o proceed_v in_o a_o constant_a order_n now_o these_o thing_n consider_v it_o may_v seem_v consentaneous_a to_o conclude_v that_o the_o motion_n of_o the_o blood_n can_v be_v continuus_fw-la since_o two_o pause_n or_o quiet_n be_v interpose_v betwixt_o every_o two_o pulsation_n or_o systole_n of_o the_o heart_n during_o each_o of_o which_o the_o motion_n cease_v but_o on_o the_o contrary_a aught_o to_o be_v esteem_v and_o call_v a_o interrupt_a and_o mix_v motion_n and_o yet_o notwithstanding_o the_o verisimilitude_n of_o this_o conclusion_n i_o doubt_v not_o to_o lay_v down_o and_o expose_v to_o your_o examination_n this_o first_o proposition_n that_o the_o blood_n be_v carry_v in_o a_o round_a through_o the_o body_n of_o a_o animal_n in_o a_o true_o continue_v and_o never_o interrupt_v motion_n this_o perhaps_o may_v sound_v like_o a_o paradox_n but_o that_o shall_v not_o a-whit_n discourage_v i_o from_o assert_v it_o while_o i_o remember_v that_o remarkable_a sentence_n of_o minutius_n felix_n in_o octavio_n inest_fw-la &_o in_fw-la incredibili_fw-la verum_fw-la &_o in_o verisimili_fw-la mendacium_fw-la though_o it_o be_v true_a and_o evident_a that_o the_o heart_n do_v not_o in_o the_o time_n of_o its_o pause_n express_v any_o blood_n into_o the_o artery_n yet_o it_o be_v not_o true_a that_o the_o blood_n contain_v in_o the_o artery_n in_o the_o viscera_n in_o the_o habit_n of_o the_o body_n and_o in_o the_o vein_n do_v at_o the_o same_o time_n stagnate_n and_o stop_v its_o course_n but_o on_o the_o contrary_n be_v always_o carry_v on_o in_o its_o journey_n though_o with_o unequal_a velocity_n first_o the_o verity_n of_o this_o appear_v in_o the_o artery_n for_o the_o afflux_n of_o blood_n from_o the_o heart_n be_v whole_o intercept_v either_o by_o a_o ligature_n apply_v to_o the_o aorta_fw-mi at_o its_o original_n or_o by_o cut_v out_o the_o heart_n itself_o as_o be_v common_o do_v in_o frog_n and_o viper_n we_o see_v that_o nevertheless_o the_o blood_n wherewith_o the_o artery_n be_v fill_v be_v by_o degree_n squeeze_v out_o so_o that_o they_o be_v soon_o after_o leave_v altogether_o empty_a and_o doubtless_o this_o exinanition_n of_o the_o artery_n happen_v because_o they_o by_o their_o own_o spontaneous_a motion_n constringe_v themselves_o and_o contract_v their_o circular_a fibre_n express_v the_o blood_n into_o the_o habit_n of_o the_o part_n and_o be_v at_o the_o same_o time_n compress_v also_o by_o the_o contraction_n and_o tension_n or_o the_o peristaltic_a motion_n of_o all_o the_o muscle_n of_o the_o body_n from_o the_o observation_n of_o this_o vulgar_a phaenomenon_n viz._n the_o emptiness_n of_o the_o artery_n in_o dead_a body_n the_o ancient_n perhaps_o take_v occasion_n to_o believe_v and_o teach_v that_o not_o blood_n but_o only_o vital_a spirit_n be_v contain_v in_o the_o artery_n second_o this_o appear_v also_o in_o the_o vein_n for_o that_o the_o blood_n do_v continual_o flow_v on_o in_o they_o likewise_o not_o only_a when_o it_o be_v urge_v forward_o by_o the_o arterial_a blood_n pursue_v it_o but_o even_o in_o the_o time_n of_o the_o heart_n pause_n be_v evince_v from_o this_o that_o then_o the_o blood_n run_v on_o through_o the_o trunk_n of_o the_o vena_fw-la cava_fw-la to_o replenish_v the_o right_a ventricle_n of_o the_o heart_n but_o why_o do_v i_o misspend_v time_n in_o allege_v reason_n to_o prove_v a_o truth_n that_o be_v manifest_a to_o sense_n in_o phlebotomy_n no_o soon_o be_v a_o vein_n open_v than_o the_o blood_n flow_v forth_o with_o a_o swift_a stream_n and_o while_o the_o wound_n be_v open_a continues_z to_o flow_v without_o pause_n or_o interruption_n which_o be_v a_o demonstration_n of_o the_o thing_n propose_v viz._n of_o the_o continual_a motion_n of_o the_o blood_n in_o the_o vein_n be_v thus_o assure_v of_o the_o effect_n let_v we_o proceed_v to_o investigate_v the_o cause_n which_o be_v not_o equal_o evident_a nor_o can_v we_o hope_v certain_o to_o solve_v this_o problem_n without_o inquire_v the_o mechanical_a reason_n of_o the_o continual_a motion_n of_o the_o blood_n through_o the_o vein_n this_o therefore_o i_o will_v now_o attempt_v to_o do_v that_o nature_n have_v institute_v no_o immediate_a communication_n betwixt_o the_o capillary_a artery_n and_o the_o capillary_a vein_n per_fw-la anastomôsin_fw-la be_v manifest_a to_o sense_n and_o now_o acknowledge_v by_o all_o learned_a anatomist_n and_o therefore_o it_o can_v stand_v with_o reason_n to_o imagine_v that_o the_o blood_n in_o its_o circular_a course_n be_v emit_v immediate_o out_o of_o the_o artery_n into_o the_o vein_n these_o vessel_n be_v separate_a and_o though_o we_o opine_n that_o there_o be_v some_o secret_a communication_n betwixt_o the_o extreme_a orifice_n of_o the_o artery_n and_o those_o of_o the_o capillary_a vein_n by_o the_o intermediate_v spongy_a substance_n of_o the_o flesh_n viscera_n and_o glandule_n or_o by_o the_o cribrose_n substance_n of_o the_o bone_n as_o by_o the_o pore_n of_o a_o pumice_n stone_n yet_o we_o be_v still_o to_o seek_v by_o what_o motive_n force_v the_o blood_n may_v be_v carry_v on_o from_o those_o intermediate_v porosity_n and_o insinuate_v into_o the_o vein_n first_o because_o it_o be_v consentaneous_a that_o the_o impulsive_a force_n whereby_o the_o systole_n of_o the_o heart_n squirt_n the_o blood_n into_o the_o artery_n be_v by_o degree_n weaken_v and_o at_o length_n languid_a in_o those_o straits_n of_o the_o extreme_a vessel_n and_o of_o the_o intermediate_v porosity_n second_o because_o the_o orifice_n of_o the_o capillary_a vein_n can_v continue_v always_o open_a and_o dilate_v their_o consistence_n be_v not_o hard_a and_o bony_a but_o membranose_n soft_a and_o slippery_a so_o that_o they_o be_v apt_a to_o be_v close_v by_o connive_v and_o consequent_o to_o hinder_v the_o ingress_n of_o the_o blood_n new_o arrive_v three_o because_o here_o we_o can_v have_v no_o recourse_n to_o the_o compression_n of_o the_o viscera_n and_o the_o muscle_n whereby_o the_o blood_n shall_v be_v squeeze_v into_o the_o orifice_n of_o the_o capillary_a vein_n for_o we_o see_v that_o the_o blood_n be_v suck_v up_o by_o the_o capillary_a vein_n not_o only_a when_o the_o muscle_n be_v invigorate_v and_o upon_o the_o stretch_n but_o also_o when_o they_o be_v quiet_a and_o relax_v and_o do_v not_o exercise_v their_o compressive_a power_n as_o be_v most_o evident_a in_o sleep_n when_o the_o circulation_n proceed_v without_o intermission_n this_o be_v confirm_v from_o hence_o that_o in_o the_o brain_n in_o the_o medullary_a substance_n of_o the_o bone_n where_o no_o compression_n can_v be_v admit_v the_o capillary_a vein_n receive_v the_o blood_n as_o free_o as_o in_o the_o soft_a flesh_n itself_o see_v then_o that_o the_o effect_n can_v be_v deny_v viz._n that_o all_o the_o blood_n effuse_v out_o of_o the_o artery_n be_v after_o absorb_v and_o carry_v off_o by_o the_o vein_n to_o be_v bring_v back_o again_o into_o the_o heart_n and_o see_v also_o that_o this_o be_v not_o effect_v by_o way_n of_o attraction_n there_o be_v no_o such_o thing_n as_o attraction_n in_o nature_n as_o i_o have_v more_o than_o once_o elsewhere_o prove_v we_o be_v compel_v to_o assert_v that_o the_o blood_n be_v imbibe_v by_o the_o capillary_a vein_n for_o the_o same_o reason_n and_o by_o the_o same_o mechanic_n action_n by_o which_o syphon_n sponge_n filtre_n chord_n and_o all_o porose_a body_n be_v penetrate_v by_o water_n with_o which_o they_o be_v moisten_v which_o power_n be_v no_o other_o than_o the_o gravity_n of_o the_o fluid_n itself_o which_o be_v augment_v by_o the_o impetus_fw-la of_o its_o proper_a motion_n and_o by_o the_o impulse_n communicate_v to_o it_o from_o external_a force_n so_o the_o motive_n force_n of_o gravity_n which_o the_o blood_n can_v want_v no_o more_o than_o water_n can_v when_o it_o find_v the_o small_a channel_n of_o the_o capillary_a vein_n open_a for_o they_o can_v never_o be_v so_o close_o constringe_v by_o the_o flag_a and_o connivency_n of_o their_o thin_a membrane_n as_o to_o leave_v no_o entrance_n for_o a_o fluid_a as_o appear_v in_o the_o pore_n of_o rope_n how_o hard_o soever_o twist_v must_v of_o necessity_n overcome_v the_o weak_a resistance_n of_o the_o straits_n in_o all_o filtre_n and_o porose_a body_n and_o consequent_o the_o blood_n may_v be_v insinuate_v into_o the_o capillary_a vein_n by_o a_o mechanic_n action_n like_o that_o of_o filtration_n if_o this_o proposition_n
blood_n which_o be_v alone_o sufficient_a to_o evince_v that_o the_o artery_n do_v not_o remain_v empty_a after_o the_o pulsation_n of_o the_o heart_n but_o contain_v at_o least_o a_o 4_o the_o part_n of_o the_o whole_a mass_n of_o blood_n which_o in_o a_o man_n be_v about_o 5_o pint_n yet_o far_o the_o artery_n in_o the_o moment_n of_o their_o pulsation_n be_v high_o turgid_a when_o yet_o not_o above_o 3_o ounce_n of_o blood_n be_v emit_v into_o they_o by_o the_o systole_n of_o the_o heart_n therefore_o if_o before_o the_o systole_n the_o artery_n be_v whole_o empty_a a_o space_n 20_o time_n great_a than_o their_o bulk_n be_v will_v inevitable_o be_v fill_v by_o the_o 3_o ounce_n of_o blood_n emit_v by_o the_o heart_n but_o this_o certain_o be_v impossible_a without_o such_o a_o rarefaction_n of_o the_o blood_n which_o no_o man_n of_o common_a sense_n will_v admit_v therefore_o to_o replenish_v so_o great_a a_o vacuity_n in_o the_o artery_n there_o must_v come_v into_o they_o five_o pint_n of_o blood_n either_o from_o the_o heart_n or_o back_o out_o of_o the_o vein_n but_o neither_o of_o these_o be_v possible_a in_o nature_n let_v we_o add_v that_o 3_o ounce_n of_o blood_n emit_v by_o the_o systole_n of_o the_o heart_n can_v fill_v a_o space_n great_a than_o half_a a_o foot_n of_o the_o next_o artery_n to_o the_o heart_n therefore_o if_o the_o artery_n be_v empty_a before_o the_o systole_n true_o all_o the_o rest_n of_o the_o artery_n will_v remain_v empty_a also_o in_o the_o follow_a systole_n and_o consequent_o can_v not_o beat_v at_o the_o same_o time_n with_o the_o heart_n and_o the_o circulation_n of_o the_o blood_n through_o they_o will_v be_v interrupt_v or_o discontinue_v contrary_a to_o the_o mechanic_a necessity_n thereof_o in_o fine_a we_o be_v convince_v by_o common_a experience_n when_o a_o artery_n whether_o it_o be_v great_a or_o small_a be_v cut_v the_o blood_n be_v in_o every_o pulsation_n squirt_v out_o with_o mighty_a violence_n now_o it_o be_v impossible_a this_o shall_v happen_v unless_o all_o the_o artery_n be_v full_a of_o blood_n all_o along_o from_o their_o beginning_n to_o their_o end_n because_o the_o violence_n of_o the_o stream_n of_o blood_n gush_v from_o the_o incision_n have_v no_o other_o efficient_a cause_n but_o the_o protrusion_n of_o the_o blood_n come_v on_o behind_o and_o urge_v the_o antecedent_n but_o in_o the_o follow_a pulsation_n there_o be_v a_o accession_n of_o no_o more_o than_o 3_o ounce_n of_o blood_n which_o can_v by_o its_o quantity_n replenish_v half_o the_o capacity_n of_o the_o artery_n therefore_o unless_o there_o remain_v after_o every_o pulsation_n 5_o pint_n of_o blood_n in_o the_o artery_n they_o can_v be_v make_v turgid_a again_o in_o the_o follow_a pulsation_n so_o that_o nothing_o be_v more_o certain_a or_o more_o evident_a than_o this_o that_o in_o a_o live_a animal_n the_o artery_n be_v never_o empty_a quod_fw-la erat_fw-la ostendendum_fw-la from_o the_o praecedent_n theorem_fw-la natural_o arise_v this_o consectary_n that_o after_o the_o pulsation_n of_o the_o heart_n there_o remain_v in_o the_o artery_n the_o 4_o the_o part_n of_o the_o whole_a mass_n of_o blood_n contain_v in_o the_o body_n of_o a_o animal_n and_o in_o a_o man_n common_o about_o 5_o pint_n and_o that_o the_o proportion_n of_o blood_n express_v by_o the_o systole_n of_o the_o heart_n into_o the_o artery_n be_v about_o one_o twenty_o part_n of_o the_o blood_n contain_v in_o they_o as_o also_o that_o 3_o ounce_n of_o blood_n eject_v out_o of_o the_o heart_n into_o the_o artery_n fill_v a_o space_n in_o the_o artery_n next_o to_o the_o heart_n no_o great_a than_o half_a a_o foot_n namely_o so_o much_o as_o be_v triple_a or_o quadruple_a to_o the_o latitude_n of_o the_o ventricles_n of_o the_o heart_n proposition_n that_o the_o motion_n of_o the_o blood_n in_o the_o artery_n be_v threefold_o swift_a than_o the_o motion_n of_o the_o heart_n that_o impell_v the_o blood_n because_o in_o the_o same_o time_n be_v absolve_v all_o these_o motion_n viz._n the_o dilatation_n of_o the_o pore_n of_o the_o heart_n the_o restriction_n of_o its_o cavity_n by_o the_o swell_a inward_a of_o the_o wall_n of_o the_o ventricles_n the_o expulsion_n of_o the_o blood_n contain_v in_o the_o ventricles_n the_o motion_n of_o the_o expulse_v blood_n in_o the_o artery_n and_o the_o promotion_n of_o the_o mass_n of_o blood_n preaexistent_a in_o they_o cause_v by_o the_o urgency_n of_o the_o new_a blood_n come_v on_o out_o of_o the_o heart_n all_o these_o action_n i_o say_v be_v perform_v in_o the_o same_o time_n and_o it_o appear_v that_o the_o three_o former_a operation_n be_v perform_v with_o the_o same_o velocity_n in_o the_o heart_n because_o the_o fibre_n of_o the_o heart_n by_o reason_n of_o their_o abbreviation_n be_v with_o the_o same_o motion_n move_v through_o the_o same_o space_n of_o the_o amplitude_n of_o the_o ventricles_n through_o which_o they_o be_v move_v by_o restr_v the_o same_o ventricles_n and_o squirt_v out_o the_o blood_n that_o be_v contain_v in_o they_o and_o the_o two_o last_o operation_n likewise_o be_v perform_v with_o the_o same_o velocity_n for_o look_v how_o much_o space_n the_o blood_n expel_v out_o of_o the_o heart_n run_v through_o in_o the_o artery_n just_o so_o much_o space_n must_v the_o mass_n of_o blood_n preaexistent_a in_o they_o be_v drive_v through_o in_o the_o same_o time_n because_o one_o part_n of_o the_o blood_n must_v give_v way_n to_o another_o urge_v it_o forward_o as_o fast_o as_o that_o come_v on_o behind_o but_o if_o the_o motion_n of_o the_o constriction_n of_o the_o heart_n be_v compare_v with_o the_o progressive_a motion_n of_o the_o blood_n in_o the_o artery_n then_o doubtless_o they_o will_v not_o be_v find_v to_o be_v of_o equal_a velocity_n because_o the_o former_a motion_n viz._n of_o the_o constriction_n of_o the_o heart_n be_v make_v through_o a_o space_n equal_a to_o the_o latitude_n of_o the_o ventricles_n of_o the_o heart_n which_o at_o most_o exceed_v not_o 3_o inch_n breadth_n but_o the_o space_n through_o which_o the_o 3_o ounce_n of_o blood_n express_v out_o of_o the_o heart_n run_v in_o the_o artery_n be_v equal_a to_o the_o length_n of_o half_a a_o foot_n therefore_o the_o space_n will_v be_v triple_a at_o least_o to_o the_o space_n of_o the_o former_a motion_n and_o yet_o both_o these_o motion_n be_v perform_v in_o the_o same_o time_n ergo_fw-la the_o motion_n of_o the_o blood_n in_o the_o artery_n be_v threefold_o swift_a than_o the_o motion_n of_o the_o heart_n that_o cause_v it_o quod_fw-la erat_fw-la propositum_fw-la i_o add_v this_o remark_n that_o the_o motion_n of_o the_o blood_n in_o the_o artery_n be_v always_o the_o same_o whether_o the_o three_o ounce_n of_o blood_n emit_v into_o they_o out_o of_o the_o heart_n exact_o fill_v the_o space_n dilate_v in_o they_o or_o whether_o any_o portion_n of_o it_o be_v after_o their_o repletion_n expel_v out_o of_o they_o for_o in_o both_o case_n the_o blood_n preaexistent_a in_o the_o artery_n be_v just_a so_o much_o promove_v in_o its_o course_n as_o 3_o ounce_n new_o emit_v take_v up_o of_o space_n which_o run_v through_o more_o of_o length_n than_o half_a a_o foot_n ¶_o ⸪_o here_o i_o can_v fair_o decline_v to_o encounter_v a_o vulgar_a error_n that_o stand_v in_o my_o way_n which_o be_v that_o the_o blood_n be_v expel_v out_o of_o the_o orifice_n of_o the_o artery_n into_o the_o substance_n of_o the_o part_n by_o no_o other_o cause_n but_o the_o constriction_n of_o the_o heart_n to_o refute_v which_o i_o will_v assert_v this_o proposition_n that_o the_o cause_n expel_v the_o blood_n out_o of_o the_o artery_n be_v not_o the_o systole_n of_o the_o heart_n alone_o but_o the_o constrictive_a or_o peristaltic_a motion_n of_o the_o artery_n themselves_o natural_o and_o necessary_o succeed_v their_o expansion_n to_o the_o pulsation_n of_o the_o heart_n two_o effect_n be_v subsequent_a viz._n the_o repletion_n of_o the_o artery_n by_o the_o blood_n emit_v into_o they_o and_o the_o expulsion_n of_o the_o same_o blood_n out_o of_o they_o into_o the_o habit_n of_o the_o part_n now_o certain_o these_o two_o operation_n can_v be_v perform_v together_o or_o at_o the_o same_o time_n because_o the_o former_a be_v do_v by_o dilatation_n and_o the_o other_o by_o constriction_n of_o the_o same_o artery_n which_o two_o contrary_a motion_n can_v be_v coincident_a wherefore_o it_o be_v of_o absolute_a necessity_n that_o the_o repletion_n of_o the_o artery_n be_v precedent_n and_o the_o evacuation_n be_v subsequent_a but_o the_o repletion_n can_v be_v make_v without_o a_o violent_a distension_n of_o the_o transverse_n or_o circular_a fibre_n of_o the_o artery_n and_o we_o all_o know_v that_o all_o the_o fibre_n of_o vessel_n no_o less_o than_o those_o
compose_v of_o the_o degree_n of_o velocity_n and_o of_o the_o quantity_n of_o blood_n impulse_v 28._o as_o that_o excellent_a mathematician_n io._n alphonsus_n borellus_n have_v full_o demonstrate_v by_o this_o stroke_n it_o be_v that_o the_o new_o empty_v and_o connive_a porosity_n of_o the_o muscle_n and_o viscera_n be_v force_v open_a and_o replenish_v with_o the_o impulsed_a blood_n that_o communicate_v to_o they_o vital_a heat_n and_o fresh_a vigour_n and_o that_o the_o torpid_a useless_a and_o excrementitious_a particle_n there_o remain_v be_v protrude_v and_o expel_v partly_o through_o the_o pore_n of_o the_o skin_n partly_o through_o vessel_n destine_v to_o their_o transportation_n and_o expulsion_n so_o that_o by_o this_o rapid_a rush_v in_o of_o the_o blood_n nature_n attain_v to_o not_o only_o a_o revive_n of_o the_o solid_a part_n of_o the_o body_n but_o also_o to_o the_o expurgation_n of_o the_o blood_n itself_o from_o its_o unprofitable_a and_o excrementitious_a part_n in_o the_o emunctory_n ordain_v for_o that_o office_n a_o three_o advantage_n be_v that_o by_o the_o same_o rapid_a velocity_n of_o the_o blood_n and_o its_o vehement_a intrusion_n into_o the_o narrow_a meatus_fw-la of_o the_o part_n the_o current_n thereof_o dislodge_v rinse_v away_o and_o carry_v with_o it_o many_o other_o amoveable_a particle_n of_o various_a kind_n saline_n sulphureous_a etc._n etc._n principal_o the_o relic_n of_o the_o nutritive_a and_o nervose_a juice_n bring_v thither_o from_o the_o brain_n which_o though_o unprofitable_a now_o to_o the_o refection_n and_o invigoration_n of_o the_o part_n in_o which_o they_o be_v leave_v may_v yet_o be_v of_o some_o use_n to_o recruit_v and_o conserve_v the_o crasis_n of_o the_o blood_n and_o to_o expedite_v the_o secretion_n of_o its_o excrement_n this_o artifice_n of_o nature_n we_o may_v more_o easy_o comprehend_v by_o observe_v that_o the_o foreign_a particle_n now_o mention_v be_v extricate_v and_o rinse_v away_o by_o the_o blood_n not_o in_o ample_a vessel_n but_o after_o the_o egress_n of_o the_o blood_n out_o of_o the_o capillary_a artery_n in_o the_o intermediate_v space_n betwixt_o they_o and_o the_o capillary_a vein_n where_o end_n innumerable_a small_a canales_n some_o of_o which_o bring_v in_o the_o nutritive_a and_o nervose_a liquor_n other_o export_v the_o superfluous_a and_o less_o profitable_a particle_n of_o they_o which_o small_a pipe_n be_v like_o the_o capillary_a root_n of_o plant_n almost_o every_o where_o disseminated_a into_o the_o fleshy_a part_n into_o the_o viscera_n and_o most_o frequent_o into_o the_o glandule_n and_o this_o seem_v to_o be_v do_v to_o the_o end_n that_o so_o many_o particle_n of_o these_o spiritual_a and_o noble_a juice_n be_v rinse_v away_o by_o and_o commix_v with_o the_o the_o blood_n may_v advance_v and_o conserve_v the_o due_a consistence_n and_o constitution_n of_o it_o now_o of_o these_o three_o considerable_a benefit_n no_o one_o seem_v to_o i_o possible_a to_o be_v attain_v otherwise_o than_o by_o the_o perpetual_a and_o rapid_a motion_n of_o the_o blood_n wherefore_o i_o be_o not_o destitute_a of_o a_o rational_a ground_n to_o support_v my_o conjecture_n that_o for_o these_o end_n nature_n think_v fit_a to_o institute_v the_o swift_a motion_n of_o the_o blood_n in_o its_o circulation_n ¶_o ⸪_o but_o what_o may_v we_o conceive_v to_o be_v the_o reason_n that_o induce_v she_o to_o institute_v also_o so_o multiply_v a_o repetition_n of_o this_o course_n of_o the_o blood_n through_o the_o same_o way_n a_o river_n we_o know_v though_o the_o water_n be_v in_o a_o continual_a flux_n be_v yet_o still_o the_o same_o river_n because_o the_o elapsed_a part_n be_v continual_o succeed_v by_o new_a water_n come_v on_o with_o the_o same_o degree_n of_o speed_n to_o supply_v it_o but_o to_o maintain_v this_o perpetual_a succession_n and_o supply_n upon_o which_o the_o identity_n of_o the_o river_n necessary_o depend_v there_o be_v require_v either_o a_o immense_a quantity_n of_o water_n from_o a_o spring_n to_o feed_v the_o current_n or_o the_o same_o elapsed_a water_n must_v be_v bring_v back_o again_o to_o the_o fountain_n whence_o it_o flow_v that_o so_o by_o perpetual_o reiterated_a circuition_n the_o course_n of_o the_o river_n may_v be_v conserve_v which_o otherwise_o will_v soon_o fail_v and_o cease_v we_o be_v then_o no_o long_o to_o admire_v that_o nature_n have_v design_v to_o bring_v the_o river_n of_o blood_n with_o a_o most_o rapid_a course_n through_o the_o whole_a body_n of_o a_o animal_n for_o the_o various_a end_n above_o explain_v and_o resolve_v to_o make_v that_o course_n perpetual_a during_o the_o life_n of_o the_o animal_n make_v use_v of_o the_o same_o expedient_a viz._n to_o repete_fw-la the_o circuition_n of_o the_o same_o blood_n without_o intermission_n for_o the_o whole_a mass_n of_o blood_n common_o find_v in_o the_o body_n of_o a_o man_n not_o exceed_v 20_o pint_n and_o that_o quantity_n not_o suffice_v to_o maintain_v the_o course_n above_o 5_o or_o 6_o first_o minute_n of_o a_o hour_n lest_o the_o current_n may_v cease_v and_o so_o life_n also_o fail_v it_o be_v necessary_a that_o the_o circulation_n of_o the_o same_o mass_n of_o blood_n shall_v be_v continual_o reiterated_a for_o the_o conservation_n of_o life_n beside_o this_o necessity_n there_o be_v many_o admirable_a use_n and_o advantage_n which_o nature_n bring_v to_o a_o animal_n by_o often_o repeat_v the_o period_n of_o the_o circuition_n of_o the_o blood_n through_o the_o same_o way_n for_o if_o the_o circulation_n be_v not_o in_o this_o manner_n reiterated_a the_o blood_n can_v not_o be_v defaecate_v from_o its_o biliose_fw-la excrement_n in_o the_o liver_n nor_o according_a to_o the_o vulgar_a opinion_n from_o the_o matter_n of_o urine_n in_o the_o kidney_n nor_o can_v either_o the_o chyle_n be_v commix_v with_o the_o blood_n in_o the_o heart_n or_o the_o lympha_fw-la be_v bring_v to_o temper_n and_o dilute_v it_o in_o the_o vein_n nor_o can_v various_a other_o operation_n necessary_a to_o the_o animal_n oeconomy_n be_v perform_v all_o which_o it_o be_v not_o difficult_a for_o i_o to_o deduce_v from_o this_o repeted_a circuition_n of_o the_o blood_n if_o the_o shortness_n of_o the_o time_n appoint_v to_o i_o for_o the_o administration_n of_o my_o present_a province_n do_v not_o oblige_v i_o to_o pass_v by_o all_o collateral_a disquisition_n and_o to_o peruse_v my_o principal_a theme_n the_o motion_n of_o the_o blood_n from_o the_o final_a cause_n of_o which_o i_o will_v therefore_o in_o a_o direct_a order_n proceed_v to_o the_o efficient_a ¶_o ⸪_o praelectio_fw-la ii_o of_o the_o heart_n and_o its_o pulsation_n to_o measure_v the_o divine_a wisdom_n elucent_fw-la in_o every_o organ_n of_o a_o animal_n by_o the_o short_a line_n of_o human_a reason_n be_v indeed_o extreme_a folly_n and_o yet_o i_o doubt_v not_o to_o applaud_v and_o follow_v the_o counsel_n of_o erasistratus_n who_o as_o galen_n relate_v advise_v physician_n to_o solve_v all_o the_o action_n natural_o do_v in_o the_o body_n of_o a_o animal_n by_o mechanic_n principle_n so_o far_o at_o least_o as_o the_o dim_a light_n of_o my_o limit_a understanding_n may_v serve_v to_o guide_v i_o in_o my_o researche_n for_o not_o to_o depend_v upon_o the_o authority_n of_o plato_n who_o say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o god_n always_o work_v by_o geometry_n or_o of_o his_o great_a disciple_n aristotle_n who_o from_o thence_o call_v god_n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d the_o mechanic_n of_o the_o world_n we_o have_v the_o great_a authority_n of_o the_o sacred_a scripture_n itself_o that_o god_n have_v frame_v all_o thing_n in_o number_n weight_n and_o measure_n whoever_o therefore_o intend_v with_o due_a care_n to_o study_v any_o part_n of_o his_o work_n must_v therein_o chief_o consider_v number_n weight_n and_o measure_n i._n e._n the_o mechanism_n of_o it_o otherwise_o in_o the_o end_n he_o will_v find_v his_o mind_n rather_o swell_v with_o opinion_n than_o fill_v with_o knowledge_n why_o then_o may_v not_o we_o who_o be_v christian_n as_o well_o as_o natural_a philosopher_n take_v those_o part_n of_o a_o animal_n to_o be_v machine_n or_o engine_n which_o evident_a reason_n and_o chief_o sense_n show_v to_o be_v such_o or_o who_o have_v prohibit_v we_o to_o investigate_v the_o formal_a reason_n and_o manner_n of_o their_o operation_n it_o be_v not_o more_o certain_a that_o no_o mortal_a can_v know_v enough_o of_o god_n work_n than_o it_o be_v that_o the_o more_o we_o be_v able_a to_o discover_v of_o his_o wisdom_n power_n and_o goodness_n discernible_a in_o the_o mirror_n of_o his_o creature_n the_o more_o we_o shall_v find_v ourselves_o oblige_v to_o admire_v love_n and_o adore_v he_o equal_o certain_a it_o be_v also_o that_o no_o kind_n of_o devotion_n be_v more_o acceptable_a to_o he_o than_o that_o which_o proceed_v from_o knowledge_n of_o his_o infinite_a
of_o the_o ventricles_n of_o the_o heart_n be_v the_o sole_a and_o immediate_a cause_n of_o the_o expression_n of_o the_o blood_n that_o be_v contain_v in_o they_o into_o the_o artery_n for_o the_o swell_a or_o incrassation_n of_o these_o opposite_a wall_n be_v all_o inward_a towards_o the_o centre_n of_o the_o heart_n and_o withal_o so_o great_a as_o to_o fill_v up_o the_o cavity_n of_o the_o ventricles_n it_o be_v necessary_a that_o the_o blood_n contain_v in_o the_o cavity_n be_v on_o all_o side_n vehement_o compress_v give_v way_n and_o flow_v forth_o through_o the_o aperture_n or_o orifice_n by_o nature_n provide_v for_o its_o efflux_n the_o resistance_n of_o the_o fluid_a blood_n hold_v very_o little_a proportion_n to_o the_o mighty_a force_n of_o the_o solid_a compress_v it_o but_o so_o grand_a a_o intumescence_n of_o the_o fleshy_a substance_n of_o the_o heart_n can_v not_o otherwise_o be_v make_v than_o by_o a_o great_a swell_a and_o turgency_n of_o its_o fibre_n and_o therefore_o we_o may_v infer_v that_o the_o thickness_n of_o the_o fibre_n of_o the_o heart_n be_v in_o the_o act_n of_o pulsation_n double_o great_a than_o in_o the_o diastole_n this_o be_v grant_v i_o consider_v that_o the_o external_a fibres_fw-fr of_o the_o heart_n exercise_v very_o great_a force_n not_o by_o shorten_v themselves_o but_o by_o resist_a distraction_n as_o the_o iron_n hoop_n of_o a_o hogshead_n that_o the_o perimeter_n of_o the_o heart_n be_v not_o augment_v and_o at_o the_o same_o time_n they_o be_v inflate_v in_o their_o concave_a part_n or_o under_o side_n as_o we_o have_v say_v the_o thread_n of_o a_o glome_z be_v and_o in_o like_a manner_n the_o internal_a fibres_fw-fr when_o they_o be_v swell_v and_o incrassated_a exercise_v very_o great_a force_n by_o make_v fold_n and_o turgid_a wrinkle_n so_o tense_n and_o rigid_a that_o they_o do_v the_o office_n of_o wedge_n by_o which_o not_o only_o the_o cavity_n of_o the_o heart_n be_v fill_v up_o but_o the_o blood_n therein_o contain_v be_v by_o vehement_a compression_n squirt_v out_o by_o a_o motion_n very_o much_o resemble_v that_o by_o which_o we_o spurt_v plum-stone_n with_o our_o thumb_n and_o forefinger_n compress_v they_o behind_o but_o the_o slender_a fleshy_a column_n hold_v in_o the_o opposite_a wall_n of_o the_o ventricles_n of_o the_o heart_n be_v at_o the_o same_o time_n also_o incrassated_a and_o withal_o shorten_v their_o fibre_n be_v swell_v and_o corrugate_v to_o help_v fill_v up_o the_o cavity_n yet_o they_o exercise_v great_a force_n to_o perform_v the_o office_n of_o wedge_n they_o exercise_v none_o towards_o the_o draw_v together_o the_o opposite_a wall_n of_o the_o ventricles_n because_o themselves_o be_v lax_n by_o reason_n of_o the_o corrugation_n and_o shrink_n of_o the_o length_n of_o their_o fibre_n and_o beside_o this_o they_o can_v never_o exact_o conjoin_v the_o opposite_a wall_n because_o be_v of_o a_o musculose_a constitution_n they_o can_v be_v total_o shorten_v the_o nature_n of_o the_o muscle_n be_v such_o as_o suffer_v not_o contraction_n great_a than_o the_o three_o part_n of_o their_o length_n yet_o it_o can_v be_v deny_v but_o these_o musculose_a column_n serve_v as_o cord_n to_o retain_v and_o conserve_v the_o due_a disposition_n of_o the_o internal_a part_n of_o the_o heart_n and_o to_o prevent_v the_o immoderate_a distension_n and_o distraction_n of_o the_o ventricles_n which_o too_o great_a a_o quantity_n of_o blood_n rush_v into_o they_o out_o of_o the_o vein_n may_v otherwise_o cause_v final_o the_o papillae_fw-la or_o little_a fleshy_a teat_n stand_v up_o within_o the_o ventricles_n and_o to_o which_o the_o membranose_a filament_n of_o the_o triangular_a valve_n of_o the_o heart_n be_v fasten_v do_v also_o act_v their_o part_n in_o this_o scene_n not_o only_o by_o admit_v the_o like_a inflation_n of_o their_o fibre_n but_o also_o by_o firm_o erect_v themselves_o ad_fw-la instar_fw-la penis_fw-la all_o these_o thing_n be_v verify_v in_o the_o left_a ventricle_n and_o in_o the_o ear_n of_o the_o heart_n but_o in_o the_o right_a ventricle_n where_o be_v not_o find_v a_o equal_a number_n of_o column_n the_o constriction_n be_v make_v by_o incrassation_n of_o the_o external_a wall_n namely_o by_o inflation_n and_o decurtation_n of_o the_o fibre_n thereof_o so_o that_o the_o hollow_a crookedness_n of_o it_o by_o swell_v inward_a come_v near_o to_o a_o plane_n and_o the_o arch_n within_o become_v straight_o also_o the_o inflation_n and_o swell_a of_o the_o septum_fw-la cordis_fw-la or_o middle_a wall_n of_o the_o heart_n of_o great_a thickness_n natural_o contribute_v not_o a_o little_a to_o the_o repletion_n of_o the_o right_a ventricle_n for_o hence_o it_o be_v that_o the_o convex_a superfice_n thereof_o do_v become_v more_o prominent_a and_o stretch_v out_o whence_o that_o space_n resemble_v the_o figure_n of_o a_o concave_a lens_n be_v fill_v up_o and_o the_o wall_n mutual_o touch_v the_o circuit_n of_o the_o lenticular_a cavity_n remain_v still_o the_o same_o now_o this_o whole_a operation_n be_v exact_o conform_v to_o the_o institute_n of_o nature_n which_o primary_o fill_v and_o amplify_v the_o pore_n of_o the_o spongy_a fibres_fw-fr by_o the_o humectation_n above_o explain_v from_o which_o she_o attain_v to_o a_o double_a effect_n for_o in_o the_o muscle_n of_o the_o limb_n that_o swell_a of_o the_o pore_n of_o the_o fibre_n produce_v a_o secundary_a effect_n which_o be_v the_o decurtation_n of_o the_o muscle_n and_o the_o strong_a traction_n of_o the_o joint_n but_o in_o the_o heart_n from_o the_o very_a inflation_n of_o the_o fibre_n and_o consequent_a incrassation_n of_o the_o wall_n she_o effect_n the_o repletion_n of_o the_o ventricles_n but_o the_o machine_n be_v the_o same_o in_o both_o namely_o the_o force_n of_o a_o wedge_n dilate_v the_o pore_n of_o the_o fibre_n but_o that_o this_o expression_n of_o the_o blood_n out_o of_o the_o heart_n be_v not_o make_v by_o a_o spiral_n contorsion_n or_o twist_v of_o the_o heart_n such_o as_o that_o by_o which_o water_n be_v common_o squeeze_v out_o of_o a_o wet_a napkin_n as_o some_o late_a writer_n cord_n have_v think_v be_v easy_o to_o be_v prove_v i_o acknowledge_v it_o to_o be_v most_o true_a that_o the_o expression_n of_o the_o blood_n out_o of_o the_o heart_n no_o less_o than_o the_o wring_n of_o water_n out_o of_o a_o wet_a cloth_n be_v make_v by_o constriction_n of_o the_o cavity_n and_o pore_n which_o be_v fill_v by_o the_o fluid_a but_o at_o the_o same_o time_n i_o deny_v that_o such_o a_o constriction_n be_v make_v in_o the_o heart_n and_o such_o a_o expression_n of_o the_o blood_n thence_o by_o the_o same_o cause_n the_o same_o organ_n and_o the_o same_o mechanic_n action_n by_o which_o water_n be_v squeeze_v out_o of_o wreathe_v linen_n for_o in_o a_o linen_n cloth_n before_o its_o contorsion_n the_o thread_n be_v all_o lax_n and_o therefore_o they_o admit_v many_o interstice_n that_o may_v be_v fill_v with_o little_a drop_n of_o water_n afterwards_o the_o cloth_n be_v strong_o twist_v the_o thread_n be_v force_v to_o make_v many_o circuit_n about_o the_o twist_n of_o almost_o the_o same_o altitude_n and_o so_o they_o must_v not_o only_o be_v much_o elonge_v in_o those_o prolix_a gire_n but_o also_o extenuate_v and_o stretch_v and_o consequent_o their_o side_n be_v make_v smooth_a by_o extension_n of_o their_o fold_n and_o wrinkle_n will_v mutual_o touch_v and_o their_o interstice_n vanish_v whence_o the_o little_a drop_n of_o water_n that_o be_v in_o they_o before_o will_v present_o be_v squeeze_v out_o but_o in_o the_o heart_n the_o repletion_n of_o the_o ventricles_n be_v perform_v in_o a_o manner_n far_o different_a from_o this_o for_o in_o the_o act_n of_o pulsation_n the_o bulk_n of_o the_o heart_n be_v not_o extenuate_v or_o diminish_v but_o rather_o augment_v in_o a_o double_a proportion_n nor_o be_v the_o fibre_n of_o the_o heart_n elonge_v but_o rather_o contract_v as_o the_o nature_n of_o all_o muscle_n require_v the_o same_o fibre_n do_v not_o mutual_o touch_v nor_o be_v their_o interstice_n fill_v up_o by_o reason_n of_o violent_a traction_n and_o extension_n but_o of_o their_o inflation_n notwithstanding_o this_o we_o be_v not_o to_o think_v that_o the_o spiral_n disposition_n of_o the_o fibre_n of_o the_o heart_n be_v of_o no_o use_n for_o they_o serve_v to_o the_o firm_a bind_n or_o hoop_v as_o it_o be_v of_o the_o wall_n thereof_o that_o the_o face_n and_o configuration_n of_o the_o heart_n may_v continue_v still_o the_o same_o which_o nature_n have_v provide_v for_o also_o by_o girth_n of_o other_o fibre_n wound_v round_o about_o from_o the_o external_a tendinose_n orifice_n of_o the_o vessel_n of_o the_o heart_n to_o the_o column_n within_o and_o with_o admirable_a artifice_n decussated_a and_o weave_v together_o and_o thus_o we_o have_v make_v good_a our_o
carry_v on_o the_o resemblance_n a_o little_a far_o i_o soon_o discover_v the_o disparity_n to_o be_v so_o many_o and_o so_o great_a that_o it_o be_v impossible_a to_o reconcile_v they_o into_o a_o just_a analogy_n whereupon_o condemn_v the_o extravagance_n of_o my_o fancy_n i_o sober_o conclude_v that_o the_o heart_n of_o a_o animal_n be_v a_o engine_n never_o to_o be_v imitate_v by_o human_a art_n and_o i_o find_v myself_o more_o incline_v to_o applaud_v the_o judgement_n of_o that_o prodigy_n of_o mathematical_a knowledge_n archimedes_n of_o syracuse_n for_o never_o attempt_v to_o counterfeit_v the_o motion_n of_o the_o heart_n than_o to_o admire_v his_o wit_n show_v in_o make_v a_o sphere_n of_o glass_n athan._n 1._o kircher_n deny_v that_o any_o part_n of_o it_o be_v glass_n but_o only_o the_o outside_n that_o man_n may_v discern_v the_o wheel_n and_o motion_n within_o which_o represent_v the_o perfect_a order_n and_o motion_n of_o the_o celestial_a body_n and_o which_o claudian_n describe_v in_o one_o of_o his_o epigram_n now_o if_o we_o desire_v clear_o to_o understand_v this_o inimitable_a excellency_n of_o the_o machine_n of_o the_o heart_n and_o in_o what_o propriety_n of_o it_o the_o same_o do_v chief_o consist_v we_o shall_v be_v oblige_v well_o to_o consider_v two_o thing_n neither_o of_o which_o have_v yet_o be_v explicate_v by_o we_o and_o without_o a_o due_a explication_n of_o both_o which_o all_o that_o we_o have_v hitherto_o say_v concern_v the_o motion_n of_o the_o heart_n will_v be_v maim_v and_o unsatisfactory_a these_o be_v the_o mighty_a and_o incredible_a motive_n force_v of_o the_o heart_n by_o which_o it_o express_v the_o blood_n out_o of_o the_o ventricles_n and_o the_o efficient_a cause_n of_o its_o motion_n thing_n so_o worthy_a to_o be_v know_v that_o i_o need_v not_o deprecate_v your_o impatience_n most_o candid_a and_o accomplish_a auditor_n if_o i_o detain_v you_o a_o few_o minute_n long_o while_o i_o inquire_v into_o they_o as_o to_o the_o first_o therefore_o viz._n the_o admirable_a motive_n force_v of_o the_o heart_n since_o the_o round_a and_o conical_a figure_n of_o the_o heart_n do_v not_o permit_v we_o to_o attempt_v the_o measure_n of_o its_o motive_n power_n by_o the_o same_o way_n by_o which_o the_o most_o learned_a alphonsus_n borellus_n have_v with_o singular_a sagacity_n measure_v the_o force_n of_o very_a many_o other_o muscle_n of_o man_n body_n namely_o by_o weight_n suspend_v by_o they_o and_o since_o therefore_o in_o this_o disquisition_n we_o can_v from_o the_o effect_n proceed_v to_o the_o knowledge_n of_o the_o cause_n we_o be_v compel_v from_o some_o other_o sign_n to_o raise_v a_o probable_a conjecture_n whence_o we_o may_v investigate_v the_o greatness_n of_o the_o effect_n and_o this_o sign_n shall_v be_v the_o similitude_n and_o analogy_n which_o the_o muscule_n of_o the_o heart_n seem_v to_o hold_v to_o other_o muscle_n of_o the_o same_o animal_n let_v we_o then_o with_o the_o same_o excellent_a mathematician_n borellus_n in_o who_o footstep_n i_o now_o again_o tread_v suppose_v that_o all_o even_o the_o least_o fibres_fw-fr or_o little_a machine_n of_o the_o same_o or_o divers_a muscules_n in_o the_o same_o animal_n be_v equal_o strong_a and_o exercise_v a_o equal_a motive_n force_n in_o the_o same_o time_n in_o the_o state_n of_o health_n and_o because_o equal_a bulk_n of_o two_o muscle_n contain_v equal_a multitude_n of_o the_o least_o fibres_fw-fr it_o follow_v that_o if_o we_o have_v foreknow_v the_o total_a motive_n power_n of_o one_o of_o the_o two_o equal_a muscle_n we_o shall_v be_v able_a thence_o to_o conjecture_v what_o be_v the_o total_a power_n motive_n also_o of_o the_o other_o therefore_o the_o fleshy_a bulk_n of_o the_o heart_n be_v of_o almost_o equal_a magnitude_n to_o the_o bulk_n of_o one_o of_o the_o temporal_a muscle_n and_o of_o one_o of_o the_o masseter_n and_o borellus_n have_v demonstrate_v to_o we_o the_o total_a motive_n force_v of_o those_o two_o muscle_n we_o may_v probable_o infer_v that_o the_o motive_n force_n of_o the_o heart_n be_v equal_a to_o that_o which_o those_o two_o muscle_n shut_v the_o mandible_a exercise_n now_o because_o no_o entire_a fiber_n of_o these_o two_o muscle_n be_v less_o than_o two_o inch_n long_a take_v all_o the_o fibres_fw-fr one_o with_o another_o that_o the_o excess_n of_o the_o long_a may_v compensate_a the_o defect_n of_o the_o short_a and_o because_o in_o a_o inch_n space_n of_o every_o single_a fiber_n we_o may_v imagine_v more_o than_o twenty_o little_a machine_n or_o rhomboid_a pore_n contain_v like_o the_o link_n of_o a_o chain_n in_o a_o watch_n or_o the_o mesh_n of_o a_o net_n in_o a_o row_n one_o above_o another_o let_v we_o notwithstanding_o suppose_v no_o more_o than_o ten_o small_a fibre_n to_o be_v contain_v in_o that_o space_n therefore_o in_o the_o length_n of_o every_o one_o of_o the_o fibre_n that_o compose_v the_o say_v two_o muscle_n there_o will_v be_v contain_v more_o than_o twenty_o of_o those_o most_o minute_n machine_n and_o since_o the_o weight_n of_o 150_o pound_n may_v be_v suspend_v by_o one_o single_a stratum_n or_o layer_n of_o these_o small_a machine_n of_o the_o same_o muscle_n therefore_o that_o we_o may_v have_v the_o whole_a force_n that_o nature_n exercise_v in_o those_o muscle_n the_o force_n of_o that_o one_o layer_n viz._n that_o which_o be_v able_a to_o sustain_v 150_o pound_n aught_o to_o be_v twenty_o time_n multiply_v wherefore_o the_o whole_a force_n that_o nature_n exercise_n to_o dilate_v all_o the_o rhomboid_a mesh_n or_o pore_n of_o the_o say_v two_o muscle_n when_o they_o act_v be_v great_a than_o the_o force_n of_o 3000_o pound_n weight_n and_o will_v if_o apply_v to_o the_o opposite_a end_n of_o the_o beam_n of_o a_o balance_n preponderate_a if_o then_o every_o most_o minute_n fiber_n of_o the_o heart_n exercise_v in_o the_o systole_n of_o it_o a_o force_n equal_a to_o that_o which_o every_o rhomboidal_a machine_n of_o the_o temporal_a or_o masseter_n muscle_n make_v when_o they_o act_v as_o most_o certain_o it_o do_v the_o motive_n power_n of_o all_o fibre_n of_o the_o muscle_n in_o the_o same_o animal_n in_o the_o state_n of_o health_n be_v equal_a and_o if_o the_o multitude_n of_o least_o fibre_n contain_v in_o those_o two_o muscle_n be_v equal_a to_o the_o multitude_n of_o most_o minute_n fibres_n contain_v in_o the_o muscle_n of_o the_o heart_n as_o the_o visible_a equality_n of_o their_o magnitude_n warrant_v we_o to_o suppose_v it_o to_o be_v we_o may_v thence_o deduce_v this_o conclusion_n that_o the_o force_n which_o all_o the_o most_o minute_n fibres_n of_o the_o heart_n when_o they_o be_v swell_v exercise_v to_o constringe_v the_o ventricles_n i._n e._n when_o they_o act_v all_o together_o exceed_v the_o force_n of_o 3000_o pound_n weight_n and_o will_v preponderate_v if_o it_o be_v apply_v to_o the_o contrary_a end_n of_o the_o beam_n of_o a_o just_a balance_n quod_fw-la erat_fw-la demonstrandum_fw-la and_o thus_o have_v i_o give_v you_o a_o summary_n of_o what_o borellus_n have_v from_o a_o long_a chain_n of_o most_o ingeniose_fw-la proposition_n and_o theorem_n in_o fine_a infer_v i_o come_v therefore_o to_o the._n second_o and_o last_o considerable_a propose_v to_o be_v inquire_v viz._n the_o efficient_a cause_n of_o this_o so_o wonderful_a motive_n force_v of_o the_o heart_n these_o seem_v to_o be_v no_o more_o than_o two_o of_o which_o one_o be_v immediate_a the_o other_o mediate_v as_o to_o the_o the_o former_a viz._n the_o immediate_a cause_n of_o the_o heart_n motive_n power_n we_o be_v not_o to_o expect_v to_o learn_v either_o what_o it_o be_v or_o whence_o it_o proceed_v from_o the_o doctrine_n of_o the_o ancient_n for_o they_o have_v observe_v that_o the_o heart_n be_v not_o as_o all_o the_o other_o muscle_n of_o the_o body_n be_v move_v ad_fw-la arbitrium_fw-la voluntatis_fw-la at_o the_o command_n of_o the_o will_n not_o only_o name_v the_o motion_n of_o those_o voluntary_a and_o the_o motion_n of_o this_o natural_a as_o they_o have_v good_a reason_n to_o do_v but_o also_o conceive_v and_o teach_v the_o cause_n of_o the_o motion_n of_o the_o heart_n to_o be_v divers_a from_o the_o cause_n of_o the_o motion_n of_o the_o rest_n of_o the_o muscle_n and_o according_o constitute_v and_o assign_v to_o the_o heart_n a_o certain_a blind_a and_o unintelligible_a pulsifick_a faculty_n whereto_o alone_o they_o ascribe_v as_o well_o the_o diastole_n as_o the_o systole_n thereof_o which_o they_o have_v no_o just_a reason_n to_o do_v to_o evince_v this_o their_o palpable_a error_n i_o will_v assert_v this_o proposition_n that_o the_o immediate_a motive_n cause_n of_o the_o heart_n be_v the_o very_a same_o with_o that_o by_o which_o the_o muscle_n of_o the_o limb_n be_v move_v voluntary_o first_o it_o be_v most_o evident_a to_o sense_n that_o
the_o consequent_a abbreviation_n of_o a_o cable_n to_o be_v of_o so_o great_a efficacy_n that_o the_o violence_n of_o a_o tempest_n the_o weight_n and_o jerk_n of_o a_o load_a ship_n of_o 1000_o tun_n burden_n and_o the_o current_n of_o the_o sea_n can_v by_o their_o unite_a force_n extend_v the_o cable_n to_o its_o former_a length_n this_o you_o will_v confess_v to_o be_v admirable_a that_o a_o little_a water_n insinuate_v itself_o into_o the_o pore_n of_o the_o thread_n of_o which_o the_o cable_n be_v compose_v shall_v dilate_v those_o little_a and_o indiscernible_a pore_n with_o such_o prodigious_a force_n as_o not_o only_o to_o swell_v the_o close_a and_o hard_o twist_a cable_n but_o to_o countervail_v nay_o exceed_v the_o aggregate_v of_o the_o force_n of_o a_o furious_a wind_n a_o strong_a current_n of_o the_o sea_n and_o the_o weight_n of_o so_o great_a a_o ship_n with_o its_o whole_a freight_v yet_o common_a experience_n testify_v this_o to_o be_v true_a the_o second_o example_n will_v perhaps_o raise_v your_o admiration_n to_o a_o high_a degree_n be_v of_o all_o of_o this_o kind_n that_o hitherto_o i_o have_v ever_o read_v or_o hear_v of_o the_o most_o memorable_a it_o be_v this_o in_o rome_n there_o stand_v at_o this_o day_n a_o obelisk_n of_o one_o solid_a stone_n a_o kind_n of_o ophite_n or_o spot_a marble_n ancient_o consecrate_v to_o the_o honour_n of_o the_o great_a julius_n caesar_n and_o erect_v in_o the_o cirque_fw-la of_o nero_n but_o in_o the_o year_n of_o our_o lord_n 1586._o remove_v into_o a_o more_o eminent_a place_n at_o the_o vast_a charge_n of_o pope_n sixtus_n quintus_fw-la and_o by_o the_o admirable_a skill_n of_o dominicus_n fontanus_n a_o excellent_a architect_n and_o engineer_n this_o stone_n be_v in_o height_n 170_o foot_n above_o the_o base_a in_o breadth_n at_o the_o bottom_n 12_o foot_n and_o at_o the_o top_n 8_o in_o weight_n 9586148_o pound_n and_o the_o weight_n of_o the_o cable_n chord_n pulley_n and_o other_o movable_a instrument_n use_v in_o raise_v it_o amount_v to_o 1042824_o pound_n according_a to_o the_o computation_n of_o georgius_n draudius_n 131._o the_o remove_n and_o erection_n of_o this_o obelisk_n be_v think_v to_o be_v so_o rare_a a_o work_n of_o art_n that_o the_o engineer_n beside_o the_o great_a mass_n of_o treasure_n he_o receive_v for_o a_o reward_n from_o his_o holiness_n thereby_o acquire_v to_o himself_o immortal_a renown_n no_o less_o than_o 56_o learned_a man_n have_v since_o profest_o write_v to_o describe_v his_o machine_n then_o use_v and_o to_o celebrate_v his_o praise_n as_o monantholius_n relate_v 19_o but_o all_o their_o praise_n notwithstanding_o he_o owe_v no_o small_a part_n of_o his_o honour_n to_o fortune_n or_o rather_o to_o a_o carter_n that_o stand_v by_o a_o idle_a spectator_n for_o the_o engineer_n a_o little_a mistake_v in_o his_o forecast_n of_o the_o stretch_n of_o the_o cable_n and_o rope_n find_v when_o he_o come_v to_o set_v the_o erect_a obelisk_n upon_o the_o pedestal_n that_o he_o have_v not_o raise_v it_o high_a enough_o by_o 2_o or_o 3_o inch_n and_o to_o raise_v it_o high_o with_o those_o machine_n so_o stretch_v be_v impossible_a confound_v with_o shame_n and_o despair_v by_o this_o unforeseen_a faileur_n he_o begin_v to_o meditate_v flight_n to_o save_v his_o life_n which_o he_o have_v pawn_v to_o the_o pope_n to_o be_v forfeit_v if_o he_o do_v not_o accomplish_v the_o difficult_a work_n he_o have_v undertake_v when_o as_o good_a luck_n will_v have_v it_o out_o of_o the_o crowd_n of_o vulgar_a gazer_n come_v a_o carter_n and_o advise_v he_o to_o cause_v all_o his_o cable_n and_o rope_n to_o be_v wet_a with_o water_n which_o do_v the_o rope_n quick_o swell_v and_o shorten_v themselves_o so_o that_o they_o lift_v up_o the_o column_n to_o a_o due_a height_n and_o then_o the_o overjoy_v fontanus_n with_o ease_n place_v it_o upon_o the_o pedestal_n now_o if_o you_o shall_v be_v please_v to_o reflect_v upon_o this_o example_n and_o to_o consider_v that_o a_o little_a water_n only_o by_o dilate_v the_o pore_n of_o the_o thread_n of_o the_o cable_n and_o rope_n swell_v and_o shorten_v they_o with_o force_n great_a enough_o to_o overcome_v the_o immense_a gravity_n both_o of_o the_o obelisk_n and_o of_o themselves_o with_o the_o rest_n of_o the_o mechanic_n apparatus_n then_o use_v which_o gravity_n have_v be_v compute_v to_o your_o hand_n i_o be_o confident_a you_o will_v no_o long_o think_v it_o impossible_a for_o a_o few_o little_a drop_n of_o liquor_n diffuse_v through_o the_o fibre_n of_o the_o heart_n and_o like_a wedge_n dilate_v their_o little_a mesh_n or_o pore_n so_o to_o swell_v and_o abbreviate_v they_o as_o to_o cause_v a_o constriction_n of_o the_o ventricles_n and_o that_o too_o with_o a_o force_n if_o borellus_n his_o estimate_n be_v right_a exceed_v the_o force_n of_o 3000_o pound_n weight_n and_o as_o for_o the_o probability_n of_o this_o proposition_n that_o can_v be_v obscure_a to_o any_o man_n of_o common_a sense_n who_o shall_v consider_v first_o the_o near_a similitude_n that_o be_v between_o the_o thread_n of_o a_o chord_n and_o the_o fibre_n of_o the_o heart_n in_o figure_n in_o tenacity_n and_o strength_n in_o aptness_n to_o swell_v and_o consequent_o to_o shorten_v themselves_o upon_o humectation_n and_o in_o the_o faculty_n of_o restore_v themselves_o to_o their_o natural_a tone_n after_o extension_n and_o then_o the_o little_a or_o no_o difference_n betwixt_o water_n and_o the_o succus_a nervosus_n as_o to_o the_o power_n of_o insinuate_v into_o and_o dilate_v the_o pore_n of_o body_n natural_o apt_a to_o swell_v and_o shrink_v for_o since_o the_o two_o agent_n viz._n water_n and_o the_o succus_fw-la nervosus_fw-la be_v so_o alike_o in_o their_o efficacy_n as_o to_o the_o dilatation_n of_o the_o pore_n of_o tensile_n body_n and_o since_o the_o two_o patient_n also_o viz._n the_o thread_n of_o a_o chord_n and_o the_o fibre_n of_o the_o heart_n have_v so_o full_a a_o resemblance_n in_o their_o nature_n it_o be_v high_o probable_a if_o not_o necessary_a that_o like_a effect_n shall_v be_v produce_v by_o they_o and_o this_o probability_n be_v the_o great_a because_o of_o all_o other_o efficient_a cause_n hitherto_o excogitated_a by_o learned_a man_n to_o solve_v the_o grand_a phaenomenon_n of_o the_o pulsation_n of_o the_o heart_n none_o can_v be_v give_v which_o be_v either_o so_o intelligible_a or_o so_o congruous_a to_o the_o whole_a mechanism_n of_o the_o heart_n as_o this_o which_o i_o have_v in_o this_o lecture_n endeavour_v to_o assert_v but_o this_o chair_n do_v not_o make_v i_o a_o judge_n to_o hear_v and_o determine_v most_o excellent_a precedent_n and_o my_o most_o learned_a colleague_n be_v your_o right_n which_o i_o ought_v not_o to_o usurp_v i_o will_v therefore_o first_o to_o ease_v your_o memory_n reduce_v into_o few_o word_n the_o head_n of_o what_o i_o have_v deliver_v concern_v the_o efficient_a cause_n of_o the_o motion_n of_o the_o heart_n and_o then_o humble_o and_o without_o reserve_n submit_v all_o part_n of_o my_o disquisition_n for_o i_o pretend_v not_o to_o know_v but_o only_o to_o inquire_v truth_n to_o your_o examen_fw-la and_o judgement_n the_o sum_n of_o the_o precedent_n hypothesis_n be_v this_o i_o suppose_v first_o that_o the_o immediate_a efficient_a of_o the_o pulsation_n or_o constriction_n of_o the_o heart_n be_v the_o abbreviation_n of_o the_o fibre_n of_o it_o arise_v from_o the_o dilatation_n or_o expansion_n of_o their_o pore_n or_o little_a mesh_n second_o that_o the_o mediate_v efficient_a be_v the_o succus_fw-la nervosus_fw-la derive_v from_o the_o brain_n through_o the_o cardiac_n nerve_n which_o be_v instill_v into_o and_o diffuse_v through_o the_o fibre_n of_o the_o heart_n fill_v and_o dilate_v their_o pore_n and_o by_o necessary_a consequence_n abbreviate_v they_o with_o force_n sufficient_a to_o make_v the_o systole_n or_o constriction_n of_o the_o ventricles_n and_o to_o express_v the_o blood_n contain_v in_o they_o three_o that_o the_o short_a quiet_n or_o pause_v intercede_v betwixt_o the_o systole_n of_o the_o heart_n arise_v from_o equal_a pause_n or_o intermission_n betwixt_o the_o drop_n of_o the_o succus_fw-la nervosus_fw-la instill_v into_o and_o swell_v the_o fibre_n of_o the_o heart_n and_o that_o as_o the_o time_n of_o the_o dropping_n be_v equal_a among_o themselves_o so_o be_v also_o the_o systole_n of_o the_o heart_n isochronic_a or_o aequitemporaneous_a four_o that_o the_o motion_n and_o guttulation_n of_o the_o succus_fw-la nervosus_fw-la into_o the_o fibre_n of_o the_o heart_n be_v accelerate_a or_o retard_v by_o whatsoever_o cause_n the_o systole_n of_o the_o heart_n must_v be_v more_o or_o less_o frequent_a proportionate_o thereto_o which_o thing_n if_o you_o now_o at_o length_n shall_v judge_v to_o be_v consentaneous_a to_o right_a reason_n agreeable_a to_o the_o animal_n oeconomy_n