guilty_a of_o a_o no_o small_a fault_n in_o force_v if_o i_o may_v say_v so_o his_o patient_n to_o drink_v wine_n and_o to_o eat_v solid_a food_n during_o the_o whole_a time_n of_o continue_a fever_n and_o in_o time_n of_o the_o fit_a in_o ague_n for_o though_o in_o the_o abatement_n of_o the_o one_o and_o the_o intermission_n of_o the_o other_o that_o kind_n of_o nourishment_n may_v back_o and_o fortify_v the_o operation_n of_o the_o remedy_n yet_o they_o considerable_o oppress_v the_o patient_n when_o nature_n be_v take_v up_o in_o defend_v herself_o against_o the_o vigour_n of_o the_o distemper_n that_o attack_n she_o and_o then_o it_o appear_v that_o the_o prudence_n and_o skill_n of_o a_o learned_a and_o experience_a physician_n be_v at_o least_o of_o as_o great_a relief_n on_o such_o occasion_n as_o the_o most_o efficacious_a and_o salutory_a medicine_n i_o have_v no_o more_o to_o say_v to_o show_v how_o little_a confidence_n we_o ought_v to_o have_v in_o such_o kind_n of_o empiric_n but_o that_o it_o be_v strange_a that_o this_o man_n who_o have_v prescribe_v to_o we_o so_o many_o juice_n and_o such_o like_a trifle_n about_o the_o composition_n of_o his_o febrifuge_n whereof_o the_o principle_n effect_n be_v only_o to_o be_v attribute_v to_o the_o jesuit_n powder_n shall_v conceal_v the_o use_n that_o he_o make_v of_o opium_n whereof_o he_o many_o time_n add_v some_o drop_n of_o tincture_n to_o this_o febrifuge_n which_o may_v be_v of_o great_a advantage_n when_o it_o be_v give_v seasonable_o in_o over_o watch_n light_a headedness_n and_o looseness_n which_o be_v frequent_a symptom_n in_o fever_n and_o always_o allay_v by_o the_o virtue_n of_o that_o excellent_a medicine_n i_o hope_v the_o reader_n will_v take_v in_o good_a part_n that_o i_o describe_v in_o this_o place_n a_o febrifuge_n opiate_n prepare_v with_o quinquina_fw-la and_o afterward_o explain_v its_o effect_n with_o relation_n to_o the_o nature_n of_o fever_n and_o ague_n a_o excellent_a febrifuge_n take_v of_o the_o jesuit_n powder_n the_o flower_n or_o leaf_n of_o lesser_a centaury_n subtle_o pulverize_v and_o of_o treacle_n of_o each_o a_o like_a weight_n make_v they_o into_o a_o opiate_n of_o which_o the_o patient_n twice_o a_o day_n shall_v take_v the_o weight_n of_o a_o drachm_n and_o a_o half_a during_o the_o space_n of_o six_o day_n drink_v upon_o it_o a_o glass_n of_o good_a claret_n with_o plantin_n or_o bugloss_n water_n reflection_n upon_o the_o use_n of_o this_o febrifuge_n the_o excellency_n of_o a_o remedy_n be_v very_o often_o the_o cause_n why_o it_o be_v despise_v antimony_n have_v be_v in_o our_o day_n a_o manifest_a instance_n of_o this_o but_o the_o jesuit_n powder_n and_o the_o english_a febrifuge_n continue_v we_o more_o plain_o of_o the_o truth_n of_o it_o so_o soon_o as_o chance_v or_o industry_n have_v discover_v a_o secret_a for_o any_o particular_a distemper_n the_o people_n lie_v hold_v on_o it_o as_o of_o a_o public_a good_a and_o apply_v it_o indifferent_o to_o all_o sort_n of_o evil_n and_o if_o on_o some_o occasion_n it_o succeed_v not_o as_o it_o must_v unavoidable_o come_v to_o pass_v it_o be_v cry_v down_o with_o as_o much_o zeal_n and_o precipitance_n as_o it_o be_v bring_v in_o vogue_n this_o be_v the_o fortune_n of_o all_o the_o new_a febrifuge_n have_v see_v wonderful_a effect_n of_o they_o in_o some_o kind_n of_o fever_n man_n take_v they_o for_o universal_a remedy_n but_o so_o soon_o as_o they_o find_v they_o produce_v bad_a consequence_n in_o other_o for_o which_o they_o be_v not_o proper_a it_o be_v then_o general_o conclude_v that_o it_o be_v dangerous_a to_o make_v use_n of_o they_o for_o this_o reason_n that_o all_o scruple_n may_v be_v remove_v which_o people_n may_v frame_v to_o themselves_o in_o the_o use_n of_o this_o febrifuge_n i_o have_v think_v it_o pertinent_a careful_o to_o engage_v into_o the_o nature_n of_o fever_n and_o to_o mark_v their_o difference_n to_o observe_v those_o which_o be_v submit_v to_o this_o remedy_n and_o those_o to_o which_o it_o may_v prove_v prejudicial_a and_o last_o to_o prove_v with_o how_o much_o usefulness_n it_o may_v be_v employ_v when_o that_o be_v do_v with_o all_o care_n and_o necessary_a circumspection_n two_o motion_n be_v to_o be_v conceive_v in_o the_o blood_n that_o of_o the_o whole_a which_o be_v the_o circulation_n and_o another_o of_o the_o part_n proceed_v from_o its_o liquidity_n a_o fever_n be_v a_o fermentation_n of_o the_o blood_n fermentation_n be_v a_o irregular_a motion_n of_o the_o insensible_a part_n motus_fw-la intestinus_fw-la partium_fw-la insensibilium_fw-la we_o must_v look_v into_o the_o cause_n of_o the_o regular_a motion_n of_o this_o liquid_a body_n that_o by_o the_o rule_n of_o contrary_n we_o may_v discover_v those_o of_o the_o irregular_a motion_n there_o be_v two_o cause_n that_o maintain_v uniformity_n in_o the_o motion_n of_o the_o blood_n 1._o it_o be_v quantity_n and_o the_o constant_o equal_a force_n of_o the_o spirit_n which_o be_v the_o immediate_a mover_n and_o impulser_n of_o all_o the_o part_n that_o compose_v this_o liquid_a mass_n 2._o the_o just_a proportion_n of_o the_o same_o part_n as_o well_o in_o their_o quantity_n and_o quality_n as_o in_o their_o situation_n that_o be_v to_o say_v when_o the_o sulphureous_a acide_fw-la watery_a and_o earthy_a corpuscle_n be_v not_o only_o in_o a_o laudable_a proportion_n as_o to_o quanty_a but_o likewise_o be_v so_o well_o adjust_v and_o unite_v together_o that_o they_o no_o way_n annoy_v one_o another_o and_o be_v move_v by_o the_o spirit_n or_o celestial_a matter_n that_o animate_v they_o in_o a_o regular_a and_o uniform_a motion_n as_o long_o as_o thing_n be_v thus_o it_o may_v be_v say_v that_o the_o blood_n be_v in_o its_o natural_a state_n of_o health_n and_o to_o that_o end_n the_o author_n of_o nature_n have_v not_o only_o make_v our_o body_n transpirable_a thereby_o to_o give_v vent_n to_o the_o too_o great_a quantity_n of_o spirit_n but_o have_v also_o put_v in_o different_a place_n bowel_n and_o percolatory_n design_v to_o filtrate_a the_o superfluous_a and_o exceed_a part_n which_o may_v trouble_v the_o purety_n of_o that_o liquor_n from_o thence_o it_o may_v infer_v that_o there_o be_v two_o immediate_a cause_n of_o the_o fermentation_n of_o the_o blood_n the_o first_o be_v the_o too_o great_a quantity_n or_o the_o tor_z great_a motion_n of_o the_o spirit_n which_o may_v be_v excite_v by_o the_o heat_n of_o the_o sun_n violent_a exercise_n watch_v fast_a hot_a and_o spirituous_a nourishment_n and_o the_o passion_n and_o perturbation_n of_o the_o mind_n and_o from_o thence_o it_o be_v that_o all_o fever_n ephemerae_fw-la or_o of_o one_o day_n continuance_n and_o simple_a synoche_n which_o be_v the_o slight_a of_o all_o and_o may_v be_v cure_v by_o transpiration_n alone_o do_v arise_v the_o second_o be_v the_o mixture_n of_o irregular_a and_o fermentative_a corpuscle_n rerum_fw-la non_fw-la miscibilium_fw-la mixtio_fw-la which_o confound_v the_o order_n and_o alliance_n of_o the_o part_n of_o the_o blood_n raise_v a_o sedition_n there_o and_o deprave_v its_o motion_n and_o of_o these_o body_n some_o only_o raise_v a_o simple_a fermentation_n which_o at_o length_n may_v be_v govern_v and_o subdue_v by_o nature_n and_o the_o other_o being_n more_o malignant_a and_o venomous_a cause_n coagulation_n dissolution_n and_o colliguation_n in_o the_o mass_n of_o blood_n and_o can_v in_o no_o manner_n be_v correct_v from_o the_o former_a of_o these_o proceed_v all_o intermittent_a erratic_a and_o continue_a fever_n which_o be_v call_v subintrant_fw-la and_o from_o the_o other_o spring_n burn_v pestilential_a malignant_a and_o spot_a fever_n it_o be_v now_o to_o be_v consider_v in_o what_o part_n of_o our_o body_n and_o how_o these_o humour_n be_v produce_v though_o i_o have_v say_v that_o there_o be_v part_n viscera_fw-la appoint_v for_o the_o separation_n of_o the_o superfluity_n of_o the_o blood_n yet_o see_v they_o do_v not_o always_o discharge_v their_o function_n aright_o either_o through_o a_o fault_n in_o themselves_o or_o through_o the_o too_o great_a abundance_n of_o the_o same_o superfluity_n the_o same_o be_v hurry_v away_o by_o the_o rapidity_n of_o the_o circulation_n as_o filth_n be_v carry_v away_o by_o the_o impetuous_a current_n of_o a_o river_n but_o in_o the_o same_o manner_n as_o there_o happen_v a_o turn_n in_o that_o river_n where_o the_o water_n be_v still_a and_o where_o all_o that_o filth_n turn_v slow_o with_o the_o current_n stop_v so_o these_o heterogeneous_a body_n turn_v aside_o by_o the_o coeliack_a artery_n into_o the_o branch_n of_o the_o vena_fw-la porta_n where_o the_o blood_n circulate_v more_o slow_o and_o which_o for_o that_o reason_n may_v be_v compare_v to_o a_o lake_n or_o stand_a pool_n of_o water_n in_o respect_n of_o the_o other_o vessel_n there_o it_o be_v where_o want_v
have_v be_v the_o inventor_n of_o it_o or_o that_o he_o have_v hit_v upon_o it_o by_o chance_n and_o it_o may_v be_v say_v that_o his_o boldness_n which_o will_v have_v be_v take_v for_o a_o criminal_a rashness_n in_o any_o but_o a_o empiric_n have_v not_o a_o little_a contribute_v to_o the_o knowledge_n which_o we_o have_v at_o present_a of_o its_o use_n and_o manner_n of_o application_n the_o most_o wonderful_a effect_n of_o this_o febrifuge_n appear_v in_o all_o intermittent_a fever_n which_o be_v its_o true_a object_n for_o it_o stop_v and_o in_o fine_a whole_o cure_v quotidian_n ague_n tertian_n double_a tertian_n quartan_n double_a and_o triple_a quartan_o and_o sometime_o also_o other_o kind_n of_o fever_n for_o there_o be_v some_o continue_a fever_n which_o have_v kind_n of_o intermission_n and_o regular_a paroxysm_n observable_a by_o some_o small_a cold_a in_o the_o extremity_n of_o the_o body_n or_o some_o horror_n and_o shiver_a betwixt_o the_o shoulder_n be_v cure_v by_o the_o specific_a almost_o as_o speedy_o and_o secure_o as_o the_o true_a intermittent_a fever_n and_o this_o happen_v often_o in_o respect_n of_o slow_a hectic_a fever_n accompany_v with_o a_o consumption_n such_o as_o child_n be_v common_o affect_v with_o because_o they_o have_v certain_a inequality_n of_o remission_n and_o augmentation_n which_o give_v ground_n to_o the_o remedy_n to_o exert_v its_o virtue_n to_o second_v the_o attempt_n of_o nature_n and_o by_o consequence_n to_o reduce_v the_o blood_n unto_o its_o former_a disposition_n and_o to_o restore_v the_o stomach_n to_o its_o natural_a strength_n so_o that_o for_o the_o future_a provide_v only_o good_a and_o well_o digest_v chyle_n it_o send_v a_o vivify_a humidity_n to_o all_o the_o part_n which_o correct_v their_o dryness_n and_o restore_v the_o lose_a plumpness_n and_o good_a habit_n of_o body_n it_o be_v nevertheless_o to_o be_v observe_v that_o since_o the_o matter_n of_o continue_a fever_n be_v diffuse_v through_o the_o whole_a mass_n of_o blood_n that_o herein_o it_o cause_v a_o corruption_n hard_a to_o be_v rectify_v and_o that_o it_o whole_o take_v up_o nature_n without_o give_v she_o any_o respite_n she_o can_v be_v in_o a_o condition_n to_o concur_v the_o with_o specific_a but_o till_o by_o blood_n let_v and_o purge_v the_o impure_a and_o heterogeneous_a matter_n be_v in_o some_o manner_n expulse_v the_o irritation_n of_o the_o spirin_v calm_v and_o the_o humour_n be_v in_o good_a enough_o temper_n to_o return_v into_o favour_n with_o nature_n without_o which_o the_o specific_a which_o do_v not_o always_o excite_v regular_a evacuation_n be_v not_o powerful_a enough_o to_o put_v a_o stop_n to_o the_o sedition_n and_o compose_v the_o disorder_n which_o be_v then_o in_o the_o great_a vessel_n and_o in_o all_o the_o other_o principle_n and_o more_o necessary_a part_n of_o the_o body_n for_o the_o better_a understanding_n of_o the_o abovementioned_a direction_n and_o observation_n i_o will_v have_v it_o remark_v that_o every_o thing_n that_o occasion_n a_o extraordinary_a agitation_n in_o the_o spirit_n humour_n and_o general_o in_o the_o liquid_a and_o fluid_a part_n of_o our_o body_n may_v be_v consider_v as_o the_o primitive_a cause_n of_o fever_n that_o be_v to_o say_v of_o those_o irregular_a motion_n which_o happen_v so_o often_o in_o the_o mass_n of_o blood_n but_o seem_v the_o same_o motion_n will_v be_v quick_o rectify_v by_o nature_n be_v they_o not_o keep_v in_o be_v by_o some_o permanent_a cause_n and_o that_o beside_o by_o discompose_v all_o the_o oeconomy_n of_o nature_n they_o corrupt_v the_o ferment_n that_o serve_v for_o digestion_n and_o by_o that_o mean_n render_v the_o chyle_n impure_a and_o of_o a_o bad_a quality_n the_o deprave_a chylification_n may_v be_v look_v upon_o as_o the_o immediate_a and_o antecedent_n cause_n of_o fever_n so_o that_o a_o remedy_n can_v true_o be_v a_o febrifuge_n unless_o all_o at_o once_o it_o correct_v both_o the_o bad_a disposition_n of_o stomach_n and_o of_o the_o ferment_n of_o which_o i_o have_v be_v speak_v and_o that_o be_v the_o proper_a effect_n of_o the_o english_a febrifuge_n for_o like_o the_o most_o part_n of_o bitter_a medicament_n it_o be_v very_o stomachical_a be_v proper_a to_o consume_v the_o superfluous_a humidity_n and_o to_o restore_v the_o bone_n of_o the_o relaxated_a fibre_n of_o the_o ventricle_n and_o by_o that_o mean_n to_o increase_v the_o diminish_v appetite_n and_o retrieve_v it_o when_o it_o be_v whole_o lose_v from_o whence_o depend_v the_o perfect_a digestion_n of_o the_o victual_n even_o of_o the_o most_o solid_a food_n i_o can_v tell_v if_o one_o may_v not_o affirm_v it_o to_o be_v also_o more_o cordial_a for_o beside_o that_o it_o re-establishes_a the_o scatter_a force_n of_o the_o body_n and_o the_o decay_a natural_a heat_n it_o fix_v the_o heterogeneous_a particle_n that_o cause_v the_o fermentation_n of_o the_o blood_n and_o rally_n and_o call_v together_o those_o which_o have_v be_v divide_v and_o scatter_v during_o its_o ebullition_n this_o augmentation_n of_o force_n and_o heat_n make_v it_o sometime_o appear_v as_o if_o this_o febrifuge_n do_v re-kindle_a the_o fever_n after_o the_o take_n of_o the_o first_o do_v but_o it_o only_o augment_v it_o that_o it_o may_v the_o better_o engage_v with_o it_o and_o that_o apparent_a disorder_n be_v the_o sure_a sign_n of_o its_o triumph_n for_o the_o more_o violent_a it_o render_v one_o fit_a the_o more_o we_o may_v be_v assure_v that_o it_o will_v not_o be_v follow_v by_o another_o many_o physician_n can_v conceive_v how_o this_o remedy_n which_o seem_v only_o to_o be_v fixative_a can_v radical_o cure_v fever_n and_o ague_n but_o it_o be_v to_o be_v observe_v that_o though_o it_o cause_v not_o always_o a_o sensible_a evacuation_n yet_o it_o so_o powerful_a second_v the_o inclination_n of_o nature_n that_o during_o its_o operation_n the_o heterogeneous_a impure_a or_o superfluous_a matter_n be_v most_o common_o force_v out_o to_o the_o superfice_n of_o the_o body_n to_o be_v evacuate_v by_o insensible_a transpiration_n and_o even_o very_a often_o by_o copious_a sweat_n as_o also_o it_o be_v sometime_o the_o occasion_n of_o a_o critical_a looseness_n of_o the_o belly_n and_o in_o many_o patient_n the_o way_n of_o the_o urine_n serve_v for_o so_o salutary_a a_o evacuation_n that_o it_o cure_v both_o together_o the_o quartan_a ague_n and_o the_o dropsy_n occasion_v by_o it_o furthermore_o though_o the_o most_o certain_a and_o regular_a operation_n of_o the_o english_a remedy_n be_v to_o stop_v the_o fit_n of_o intermittent_a fever_n yet_o the_o use_n of_o it_o be_v not_o to_o be_v think_v of_o dangerous_a consequence_n it_o cause_v no_o trouble_n in_o the_o oeconomy_n of_o nature_n be_v like_o other_o bitter_a temperate_a medicament_n incapable_a of_o make_v any_o bad_a impression_n on_o man_n body_n for_o the_o reunion_n that_o it_o make_v of_o the_o part_n of_o the_o blood_n always_o facilitate_v the_o expulsion_n of_o morbific_a cause_n and_o though_o they_o shall_v partly_o stay_v within_o after_o its_o operation_n yet_o by_o mean_n of_o it_o they_o be_v correct_v and_o reconcile_v to_o nature_n or_o at_o least_o by_o reiterated_a and_o continual_a digestion_n they_o be_v at_o length_n concoct_v ripen_v and_o dissipate_v observation_n of_o the_o king_n chief_a physician_n concern_v the_o practice_n of_o sir_n robert_n talbor_n in_o the_o prepation_n and_o distribution_n of_o his_o remedy_n the_o great_a secret_n of_o most_o of_o empiric_n consist_v only_o in_o disguise_v the_o the_o drug_n that_o they_o make_v use_v of_o for_o since_o they_o be_v the_o very_a same_o whereof_o physician_n know_v the_o nature_n and_o property_n they_o can_v not_o make_v they_o pass_v for_o secret_a remedy_n unless_o they_o affect_o give_v they_o a_o air_n of_o novelty_n thus_o do_v sir_n robert_n talbor_n in_o the_o preparation_n of_o the_o jesuit_n powder_n either_o to_o make_v it_o be_v believe_v that_o the_o virtue_n of_o his_o febrifuge_n do_v not_o depend_v on_o that_o book_n or_o to_o make_v it_o be_v think_v that_o he_o understand_v it_o much_o better_a than_o those_o that_o have_v make_v use_n of_o it_o before_o he_o for_o it_o be_v very_o ordinary_a with_o he_o to_o besprinkle_v fix_v drachm_n of_o red_a rose_n with_o two_o ounce_n of_o the_o juice_n of_o lemon_n and_o afterward_o to_o infuse_v they_o for_o the_o space_n of_o four_o hour_n in_o six_o pound_n of_o fountain_n water_n to_o make_v use_n of_o that_o infusion_n for_o the_o make_n of_o his_o remedy_n add_v thereunto_o eight_o ounce_n of_o quinquina_fw-la powder_v and_o besprinkle_v with_o four_o ounce_n of_o the_o juice_n of_o fennel_n root_n and_o put_v into_o infusion_n only_o for_o the_o space_n of_o twelve_o hour_n sometime_o instead_o of_o that_o juice_n he_o will_v employ_v the_o juice_n of_o smallage_n leave_v and_o at_o other_o time_n
matter_n or_o other_o morbific_a cause_n disperse_v in_o the_o humour_n or_o adhere_v to_o the_o solid_a part_n it_o be_v so_o far_o from_o that_o that_o by_o revit_v the_o homogenous_a part_n of_o the_o blood_n it_o separate_v they_o from_o the_o heterogeneous_a or_o superabundant_a part_n whereby_o it_o facilitate_v their_o expulsion_n for_o which_o nature_n alone_o do_v often_o labour_n in_o vain_a in_o the_o same_o manner_n as_o by_o strengthen_v and_o fortify_v the_o viscera_fw-la it_o put_v they_o in_o a_o condition_n of_o resist_v all_o attack_n and_o of_o discharge_v themselves_o of_o the_o impurties_n that_o oppress_v they_o experience_n well_o agree_v with_o these_o remark_n for_o the_o heat_n that_o dry_v up_o and_o consume_v the_o hectic_n be_v often_o extinguish_v by_o the_o use_n of_o several_a preparation_n of_o the_o jesuit_n powder_n it_o be_v no_o less_o powerful_a against_o all_o other_o internal_a inflammation_n fever_n and_o general_o against_o all_o extraordinary_a and_o preternatural_a fermentation_n in_o a_o very_a short_a time_n it_o rectify_v the_o deprave_a motion_n and_o the_o alter_a consistency_n of_o the_o mass_n of_o blood_n and_o it_o many_o time_n occasion_n such_o salutary_a evacuation_n that_o have_v drein_v the_o source_n of_o dropsy_n by_o the_o depuration_n of_o the_o natural_a voice_n which_o through_o their_o depravation_n and_o transudation_n be_v become_v the_o antecedent_n cause_n of_o it_o that_o it_o become_v the_o principal_a cause_n of_o the_o expulsion_n of_o the_o extravasated_a superfluity_n which_o be_v the_o conjunct_a cause_n of_o the_o same_o it_o be_v nevertheless_o strange_a that_o among_o so_o many_o author_n who_o with_o admiration_n have_v write_v of_o its_o effect_n not_o so_o much_o as_o one_o have_v take_v the_o pain_n to_o explain_v they_o by_o their_o true_a cause_n nor_o indeed_o think_v that_o it_o can_v be_v do_v for_o willis_n who_o without_o doubt_n have_v speak_v most_o judicious_o on_o that_o subject_a limit_n himself_o to_o this_o that_o have_v never_o see_v any_o other_o such_o like_a effect_n and_o not_o be_v able_a to_o ground_v a_o general_a conclusion_n upon_o a_o particular_a experiment_n all_o that_o be_v to_o be_v do_v be_v to_o endeavour_v to_o understand_v and_o well_o observe_v the_o phoenomina_fw-la that_o depend_v thereon_o without_o trouble_v one_o self_n with_o the_o efficient_a principle_n thereof_o but_o to_o make_v appear_v how_o far_o one_o may_v err_v in_o the_o explication_n of_o thing_n when_o they_o be_v not_o know_v by_o their_o proper_a cause_n it_o will_v not_o be_v amiss_o here_o to_o relate_v some_o opinion_n of_o that_o author_n touch_v the_o effect_n of_o the_o jesuit_n powder_n upon_o the_o mass_n of_o blood_n the_o first_o be_v that_o it_o always_o cause_n therein_o a_o certain_a fermentation_n that_o only_o desirous_a that_o of_o the_o fever_n because_o it_o proceed_v from_o another_o cause_n now_o the_o jesuit_n powder_n do_v indeed_o sift_v the_o fermentation_n of_o the_o blood_n and_o the_o other_o humonr_n but_o not_o excite_v any_o itself_o the_o second_o be_v that_o it_o maintain_v its_o effect_n no_o long_o than_o it_o be_v in_o the_o vessel_n and_o that_o so_o soon_o as_o all_o the_o part_n thereof_o be_v spend_v and_o go_v the_o disposition_n that_o it_o have_v suppress_v infallible_o wear_v in_o so_o much_o that_o the_o relapse_n be_v as_o certain_a as_o the_o stop_n of_o the_o fit_a nevertheless_o the_o contrary_a appear_v daily_o almost_o to_o any_o who_o know_v how_o to_o use_v it_o aright_o to_o be_v short_a the_o third_z be_v that_o it_o stop_v not_o the_o fit_v of_o the_o fever_n neither_o by_o fix_v nor_o yet_o by_o resolve_v the_o blood_n as_o other_o febrifuge_n do_v nevertheless_o it_o be_v certain_o true_a that_o the_o principal_a effect_n of_o bitter_a astringent_a and_o styptic_a februifuge_n be_v the_o reunite_a of_o the_o proper_a part_n of_o the_o blood_n divide_v and_o scatter_v by_o the_o disorder_a animal_n spirit_n or_o by_o heterogeneous_a and_o superfluous_a matter_n the_o author_n of_o the_o addition_n to_o scroderus_n have_v have_v no_o better_a luck_n in_o say_v that_o quinquina_fw-la or_o the_o jesuit_n powder_n cure_v the_o fever_n by_o the_o virtue_n that_o it_o have_v in_o precipitate_v the_o fabric_n ferment_n for_o beside_o that_o it_o be_v hard_o to_o be_v understand_v how_o a_o matter_n contain_v within_o vessel_n and_o mingle_v with_o the_o blood_n can_v be_v precipitate_v by_o a_o medicine_n who_o principal_a action_n be_v direct_o opposite_a to_o that_o of_o evacuative_n those_o kind_n of_o precipitation_n be_v only_o to_o be_v make_v by_o urine_n by_o little_a and_o little_a and_o in_o a_o considerable_a space_n of_o time_n can_v rational_o be_v attribute_v to_o the_o jesuit_n powder_n that_o act_n so_o powerful_o and_o so_o sudden_o produce_v its_o effect_n that_o many_o time_n a_o single_a do_v of_o it_o stop_n and_o prevent_v the_o immediate_o approach_v fit_a of_o a_o ague_n the_o author_n of_o the_o cure_n of_o fever_n and_o ague_n by_o quinquina_fw-la who_o make_v the_o cause_n of_o the_o fever_n to_o consist_v in_o a_o certain_a acide_fw-la ferment_n refer_v the_o effect_n of_o that_o medicine_n to_o the_o faculty_n that_o it_o have_v of_o subdue_a mortify_a and_o resolve_v that_o poison_n but_o that_o author_n have_v not_o mind_v that_o if_o in_o effect_n quinquina_fw-la be_v able_a to_o destroy_v or_o even_o to_o expel_v the_o acide_n that_o be_v in_o the_o blood_n it_o will_v not_o be_v take_v without_o entire_o pervert_v that_o liquor_n see_v it_o will_v deaden_v or_o drive_v out_o the_o very_a acide_n that_o make_v natural_o a_o part_n of_o the_o same_o and_o that_o it_o must_v necessary_o lose_v its_o form_n and_o be_v change_v into_o another_o kind_n of_o juice_n if_o the_o great_a part_n of_o one_o or_o the_o other_o of_o its_o elementary_a principle_n be_v take_v from_o it_o mr._n lameâ—y_o in_o his_o new_a course_n of_o chemistry_n be_v not_o so_o wide_a of_o the_o truth_n when_o he_o say_v that_o quinquina_fw-la do_v fix_v and_o coagulate_v the_o feverish_a humour_n much_o in_o the_o same_o manner_n as_o a_o alcali_n sift_v the_o motion_n of_o a_o acide_fw-la salt_n for_o in_o effect_v it_o be_v the_o property_n of_o that_o remedy_n to_o rally_v bring_v together_o and_o rounite_v the_o part_n of_o the_o liquid_a body_n wherewith_o it_o be_v mingle_v as_o often_o as_o it_o be_v put_v in_o action_n by_o necessary_a disposition_n but_o that_o author_n have_v omit_v to_o take_v notice_n that_o this_o reunion_n be_v only_o make_v of_o the_o proper_a part_n of_o the_o blood_n and_o that_o the_o febrifick_a matter_n remain_v confound_v in_o the_o superfluous_a serosity_n wherewith_o it_o be_v evacuate_v either_o by_o transpiration_n or_o by_o the_o way_n of_o urine_n the_o principle_n that_o i_o have_v establish_v be_v of_o another_o nature_n than_o the_o opinion_n which_o i_o have_v now_o relate_v it_o be_v plain_a clear_a just_a and_o every_o way_n conform_v to_o all_o the_o experiment_n that_o have_v hitherto_o be_v make_v upon_o the_o jesuit_n powder_n and_o i_o can_v tell_v but_o that_o i_o may_v say_v to_o all_o that_o shall_v be_v make_v hereafter_o for_o whether_o it_o be_v give_v for_o our_o sort_n of_o fever_n or_o for_o another_o for_o vapour_n against_o which_o i_o take_v it_o to_o be_v very_o good_a for_o dropsy_n or_o for_o other_o distemper_n whether_o it_o be_v give_v in_o substance_n infusion_n tincture_n opiate_n extract_n or_o quintessence_n i_o be_o persuade_v that_o its_o pincipal_a effect_n will_v always_o be_v to_o separate_v the_o proper_a and_o homogenous_a part_n of_o liquor_n from_o those_o that_o be_v heterogeneous_a and_o of_o a_o different_a nature_n to_o they_o to_o reunite_v the_o one_o and_o by_o that_o reunion_n to_o facilitate_v the_o expulsion_n of_o the_o other_o yet_o with_o this_o difference_n that_o that_o effect_n will_v be_v more_o or_o less_o considerable_a according_a to_o the_o good_a or_o bad_a use_n and_o administration_n that_o shall_v be_v make_v thereof_o moreover_o that_o we_o may_v not_o too_o slight_o pass_v over_o the_o different_a preparation_n that_o may_v be_v make_v of_o quinquina_fw-la i_o be_o not_o to_o omit_v that_o pol_n fincius_fw-la describe_v a_o kind_n of_o essence_n of_o it_o which_o be_v nothing_o else_o but_o its_o tincture_n extract_v with_o excellent_a wine_n and_o afterward_o gentle_o evaporate_v that_o sturmius_fw-la make_v a_o description_n of_o another_o much_o like_a to_o it_o that_o the_o author_n of_o the_o cure_n of_o fever_n by_o quinquina_fw-la will_v have_v it_o to_o be_v give_v in_o bolus_n extract_n fermented_a liquor_n and_o in_o infusion_n make_v in_o wine_n ale_z distil_v water_n tisance_n and_o in_o common_a water_n that_o mr._n lamery_n give_v the_o preparation_n of_o a_o tincture_n of_o a_o extract_n and_o of_o a_o
their_o former_a agitation_n they_o have_v the_o mean_n of_o fasten_v and_o unite_n together_o to_o produce_v obstruction_n which_o be_v the_o primitive_a cause_n of_o all_o fever_n of_o the_o second_o order_n and_o sometime_o but_o seldom_o of_o those_o of_o the_o three_o as_o i_o shall_v now_o illustrate_v the_o blood_n can_v be_v long_o stop_v in_o a_o place_n without_o be_v exasperate_v and_o grow_v eager_a the_o spirit_n which_o be_v constant_o in_o motion_n fly_v away_o and_o carry_v with_o they_o first_o the_o more_o volatile_a part_n than_o the_o sulphureous_a which_o blunt_a and_o edge_n of_o the_o salt_n and_o keep_v they_o as_o in_o fetter_n which_o be_v the_o cause_n that_o these_o body_n have_v now_o nothing_o to_o stop_v their_o activity_n break_v off_o and_o diffuse_v themselves_o through_o the_o mass_n of_o blood_n to_o raise_v and_o ferment_n it_o until_o that_o be_v disperse_v and_o dissolve_v in_o the_o serosity_n they_o be_v expel_v by_o the_o ordinary_a way_n or_o otherways_o do_v so_o adjust_a and_o accommodate_v themselves_o with_o the_o other_o part_n that_o they_o disturb_v their_o alliance_n and_o motion_n no_o more_o there_o be_v nothing_o in_o fever_n but_o may_v be_v explain_v by_o this_o system_a the_o obstruction_n and_o the_o ferment_n which_o remain_v in_o that_o part_n which_o be_v call_v the_o focus_n make_v the_o periodick_n fit_v and_o paroxysm_n which_o be_v sometime_o quick_a and_o sometime_o slow_a according_a as_o the_o exasperate_v humour_n be_v more_o gross_a or_o more_o subtle_a the_o duplicity_n of_o focus_n or_o magazine_n make_v the_o double_a intermittent_a fever_n in_o a_o word_n there_o happen_v sometime_o so_o many_o of_o these_o nest_n that_o give_v no_o respite_n they_o cause_v continue_v fever_n which_o may_v be_v call_v subintrant_n but_o it_o sometime_o happen_v that_o these_o acid_a salt_n whether_o through_o their_o their_z too_o long_a continuance_n in_o a_o place_n or_o by_o a_o excessive_a heat_n of_o the_o entrails_n acquire_v a_o pretty_a violent_a degree_n of_o corrosion_n and_o be_v exalt_v to_o that_o height_n as_o to_o become_v venomous_a enough_o for_o spoil_v and_o whole_o ruine_v all_o the_o oeconomy_n of_o the_o blood_n and_o cause_v those_o fever_n which_o by_o a_o general_a name_n be_v call_v malignant_a but_o since_o the_o more_o common_a cause_n of_o these_o fever_n be_v vrsenical_a salt_n diffuse_v through_o the_o air_n which_o we_o breathe_v or_o lurk_v in_o the_o food_n we_o eat_v and_o that_o it_o be_v rare_a that_o our_o natural_a heat_n which_o be_v mild_a shall_v produce_v in_o our_o body_n that_o which_o the_o most_o violent_a fire_n of_o chemist_n can_v hardly_o perform_v in_o their_o vessel_n i_o say_v it_o be_v the_o less_o ordinary_a cause_n of_o those_o kind_n of_o fever_n have_v lay_v down_o these_o principle_n i_o say_v that_o this_o remedy_n be_v useless_a for_o the_o first_o and_o dangerous_a for_o the_o three_o kind_n of_o fever_n useless_a for_o the_o first_o because_o they_o be_v common_o cure_v of_o themselves_o and_o dangerous_a for_o the_o three_o because_o a_o venomous_a body_n and_o such_o as_o in_o no_o way_n can_v be_v subdue_v nor_o correct_v ought_v never_o to_o be_v fix_v on_o the_o contrary_a it_o ought_v with_o all_o expedition_n to_o be_v drive_v out_o by_o sweat_n or_o by_o other_o way_n of_o evacuation_n but_o i_o maintain_v that_o this_o remedy_n answer_v all_o the_o indication_n that_o we_o can_v have_v for_o the_o cure_n of_o those_o of_o the_o second_o order_n the_o explication_n which_o i_o have_v give_v of_o these_o fever_n which_o by_o a_o general_a name_n may_v be_v call_v intermittent_a furnish_v i_o with_o four_o indication_n for_o their_o cure_n 1._o to_o stop_v the_o fermentation_n of_o the_o blood_n 2._o to_o fix_v and_o correct_v the_o acid_n which_o be_v the_o cause_n of_o it_o 3._o to_o dissolve_v attenuate_v and_o drive_v out_o by_o the_o ordinary_a way_n of_o evacuation_n the_o gross_a humour_n that_o make_v obstruction_n 4._o and_o last_o to_o repair_v the_o loss_n of_o the_o sulphureous_a and_o unctuous_a corpuscle_n which_o sweeten_v the_o blood_n and_o which_o be_v evaporate_v by_o its_o offervescencie_n 1._o the_o feverish_a ebullition_n of_o the_o blood_n be_v sufficient_o stop_v by_o the_o terrestrial_a and_o astringent_a part_n of_o the_o quinquina_fw-la or_o jesuit_n powder_n and_o by_o the_o lesser_a centaury_n and_o the_o opium_n that_o enter_v the_o composition_n of_o the_o treacle_n 2._o after_o so_o many_o fair_a experiment_n we_o have_v no_o cause_n to_o doubt_v but_o that_o the_o fix_a salt_n of_o the_o quinquina_fw-la be_v the_o true_a corrective_a of_o the_o fermentative_a acid_n of_o the_o fever_n 3._o of_o all_o the_o ingredient_n that_o enter_v the_o composition_n of_o treacle_n there_o be_v none_o but_o drive_v out_o by_o sweat_v and_o urine_n the_o impurity_n of_o the_o blood_n last_o we_o may_v be_v easy_o persuade_v that_o the_o lesser_a centaury_n be_v most_o proper_a for_o restore_v the_o sulphureous_a part_n of_o the_o blood_n which_o have_v be_v dissipate_v in_o the_o fermentation_n if_o we_o consider_v its_o wonderful_a virtue_n in_o consolidate_v of_o wound_n and_o if_o we_o observe_v that_o the_o reunite_a of_o separate_a part_n be_v only_o perform_v by_o a_o balsamic_a and_o unctuous_a sulphur_n wherewith_o that_o plant_n abound_v the_o wine_n that_o be_v give_v immediate_o after_o contribute_v much_o also_o to_o that_o effect_n especial_o when_o the_o activity_n of_o its_o spirit_n be_v check_v by_o the_o mixture_n of_o the_o plant_n in_o water_n which_o on_o this_o occasion_n i_o shall_v prefer_v before_o that_o of_o bugloss_n i_o pretend_v not_o for_o all_o this_o to_o exclude_v the_o general_a and_o common_a remedy_n of_o physic_n nay_o i_o maintain_v that_o in_o the_o begin_n once_o or_o twice_o blood-letting_a according_a to_o the_o strength_n and_o repletion_n of_o the_o patient_n be_v necessary_a as_o well_o for_o facilitate_v the_o circulation_n of_o the_o blood_n as_o for_o remedy_v the_o pain_n of_o the_o head_n and_o oppression_n that_o blood_n swell_v in_o the_o fermentation_n may_v cause_v in_o pass_v through_o the_o capillary_a vessel_n of_o the_o brain_n and_o lung_n this_o remedy_n be_v not_o to_o be_v give_v till_o first_o by_o a_o dissolution_n of_o cassia_n or_o catholicum_fw-la the_o excrement_n of_o the_o low_a region_n which_o may_v trouble_v its_o operation_n be_v evacuate_v and_o last_o see_v the_o blood_n like_o other_o liquor_n in_o their_o ebullition_n drive_v always_o towards_o the_o mesentery_n a_o great_a many_o impure_a and_o feculent_a part_n like_o a_o scum_n it_o be_v necessary_a in_o the_o declension_n of_o the_o evil_a to_o purge_v they_o out_o if_o one_o will_v prevent_v relapse_n and_o sometime_o more_o troublesome_a consequence_n see_v it_o appear_v by_o the_o remark_n of_o the_o king_n chief_a physician_n and_o by_o the_o forego_n reflection_n that_o opium_n may_v useful_o be_v add_v to_o the_o english_a remedy_n and_o other_o febrifuge_n of_o the_o same_o nature_n i_o make_v no_o doubt_n but_o that_o you_o will_v read_v with_o pleasure_n the_o natural_a history_n of_o that_o excellent_a medicine_n the_o history_n of_o opium_n opium_n by_o most_o of_o the_o eastern_a people_n be_v still_o name_v offium_fw-la in_o imitation_n of_o the_o greek_n who_o common_o change_v p._n into_o a_o f._n it_o be_v the_o thicken_a juice_n of_o the_o indian_a poppy_n garrias_fw-la du_fw-fr jardin_fw-fr say_v that_o these_o head_n be_v big_a enough_o to_o contain_v four_o ounce_n and_o a_o half_a our_o poppy_n yield_v also_o a_o juice_n which_o be_v thicken_v may_v pass_v for_o a_o kind_n of_o opium_n but_o it_o have_v not_o the_o efficacy_n of_o that_o which_o be_v bring_v from_o hot_a country_n the_o author_n of_o the_o poor_a man_n physician_n propose_v a_o very_a easy_a preparation_n of_o it_o he_o will_v have_v we_o pound_n the_o head_n of_o our_o poppy_n about_o the_o end_n of_o may_n than_o put_v they_o in_o digestion_n in_o white_a wine_n for_o the_o space_n of_o fifteen_o day_n and_o afterward_o by_o evaporation_n reduce_v the_o digest_v liquor_n into_o a_o due_a consistency_n the_o true_a indian_a opium_n come_v from_o the_o eastern_a country_n according_a to_o the_o testimony_n of_o garrias_fw-la du_fw-fr jardin_fw-fr and_o christopher_n de_fw-fr la_fw-fr coste_n the_o poppy_n from_o which_o it_o be_v take_v grow_v common_o enough_o in_o egypt_n and_o therefore_o merchand_n bring_v much_o of_o it_o from_o grand_a cairo_n this_o be_v in_o great_a esteem_n and_o be_v call_v thebaick_a opium_n not_o to_o mention_v the_o opium_n that_o may_v be_v make_v of_o the_o poppy_n of_o longuedoc_n and_o provence_n nor_o of_o that_o which_o be_v make_v in_o italy_n we_o may_v divide_v into_o three_o kind_n that_o which_o be_v bring_v we_o from_o the_o indies_n for_o there_o be_v one_o
sort_n of_o it_o white_a which_o the_o indian_n keep_v for_o their_o own_o use_n and_o which_o be_v only_o draw_v out_o by_o exstillation_n have_v make_v incision_n in_o the_o head_n of_o the_o poppy_n and_o it_o be_v to_o this_o proper_o that_o the_o ancient_n give_v the_o name_n of_o opium_n for_o as_o to_o the_o second_o kind_n which_o be_v black_a and_o which_o be_v extract_v only_o by_o expression_n they_o call_v it_o maeconium_n the_o three_o sort_n be_v yellowish_a and_o common_o sophisticated_a with_o the_o juice_n of_o glaucium_fw-la which_o be_v a_o herb_n who_o leave_n resemble_v those_o of_o horn_a poppy_n and_o be_v bitter_a and_o of_o a_o evil_a smell_n that_o sophistication_n be_v discover_v by_o dissolve_v that_o kind_n of_o opium_n in_o some_o liquor_n for_o because_o of_o that_o juice_n of_o glaucium_fw-la which_o be_v yellow_a it_o look_v like_o the_o tincture_n of_o saffron_n the_o good_a maeconium_n that_o be_v say_v opium_n of_o the_o second_o kind_n ought_v to_o be_v black_a bitter_a a_o little_a bite_n to_o the_o taste_n of_o a_o unpleasant_a smell_n pure_a solid_a ponderous_a inflammable_a and_o shine_v within_o when_o it_o be_v new_o break_v in_o europe_n it_o be_v only_o use_v in_o physic_n and_o most_o part_n of_o our_o physician_n be_v so_o scrupulous_a in_o use_v it_o that_o they_o seem_v to_o look_v upon_o it_o as_o a_o most_o dangerous_a poison_n though_o it_o be_v indeed_o one_o of_o the_o safe_a and_o most_o wonderful_a of_o all_o our_o medicine_n but_o the_o african_n and_o asian_o make_v extraordinory_n great_a use_n of_o it_o both_o in_o health_n and_o sickness_n for_o most_o of_o they_o take_v it_o daily_o in_o so_o large_a a_o do_v that_o it_o amount_v common_o to_o forty_o or_o fifty_o grain_n and_o sometime_o also_o to_o four_o or_o five_o drachm_n at_o least_o if_o we_o believe_v garrias_fw-la du_fw-fr jardin_fw-fr and_o which_o be_v more_o strange_a when_o they_o leave_v off_o take_v of_o it_o they_o be_v in_o danger_n of_o death_n unless_o they_o drink_v wine_n which_o their_o religion_n forbid_v the_o reason_n of_o that_o custom_n be_v because_o thereby_o they_o find_v themselves_o more_o strong_a and_o vigorous_a and_o therefore_o it_o be_v that_o the_o turk_n never_o fail_v to_o take_v of_o it_o in_o a_o great_a do_v when_o they_o be_v go_v to_o charge_v a_o enemy_n or_o attack_v a_o place_n howsoevever_o it_o be_v see_v pain_n be_v the_o cruel_a enemy_n that_o man_n have_v so_o there_o be_v nothing_o they_o ought_v to_o esteem_v more_o than_o what_o ease_v they_o of_o it_o and_o therefore_o some_o have_v call_v opium_n a_o divine_a medicine_n because_o it_o charm_v the_o most_o vehement_a pain_n by_o procure_v a_o soft_a and_o sweet_a sleep_n and_o do_v so_o quiet_a and_o still_o the_o impetuous_a motion_n of_o the_o irritated_a spirit_n and_o exalt_a fiery_a corpuscle_n that_o it_o stop_v the_o operation_n of_o all_o those_o sharp_a and_o bite_a juice_n that_o depend_v thereupon_o the_o ancient_n in_o regard_n of_o these_o admirable_a effect_n believe_v that_o the_o virtue_n of_o opium_n consist_v only_o in_o fixation_n which_o can_v not_o proceed_v but_o from_o a_o cold_a quality_n in_o the_o same_o manner_n as_o they_o believe_v that_o all_o dissolution_n depend_v on_o heat_n the_o modern_n on_o the_o contrary_a have_v observe_v that_o because_o of_o the_o country_n from_o whence_o it_o come_v its_o piercing_a smell_n and_o how_o easy_o it_o be_v dissolve_v in_o the_o spirit_n of_o wine_n it_o must_v of_o necessity_n be_v resinous_n sulphureous_a and_o consequent_o of_o the_o nature_n of_o those_o mixt_n to_o which_o a_o hot_a quality_n be_v assign_v in_o a_o word_n some_o of_o the_o late_a author_n who_o have_v write_v of_o it_o to_o reconcile_v those_o two_o opinion_n say_v that_o there_o be_v two_o substance_n in_o it_o the_o one_o cold_a which_o render_v it_o stupefactive_a and_o the_o other_o hot_a which_o give_v it_o a_o requisite_a volatility_n to_o convey_v it_o to_o the_o brain_n but_o see_v neither_o the_o one_o nor_o the_o other_o be_v in_o the_o right_n as_o not_o have_v ground_v their_o opinion_n upon_o the_o true_a nature_n of_o opium_n that_o be_v to_o say_v with_o relation_n to_o the_o number_n quality_n and_o quantity_n of_o the_o elementary_a principle_n that_o enter_v into_o its_o composition_n we_o must_v of_o necessity_n take_v another_o course_n in_o explain_v more_o exact_o the_o property_n of_o that_o rare_a medicine_n for_o that_o end_n see_v opium_n be_v of_o the_o kind_n of_o bitter_a medecine_n it_o will_v seem_v that_o i_o shall_v begin_v by_o a_o enquiry_n into_o the_o principle_n of_o bitterness_n but_o see_v i_o have_v be_v large_a enough_o on_o that_o subject_n when_o i_o treat_v of_o the_o nature_n of_o quinquina_fw-la i_o think_v it_o more_o pertinent_a to_o refer_v the_o reader_n to_o that_o place_n than_o here_o to_o make_v repetition_n which_o doubtless_o will_v be_v as_o unpleasant_a as_o useless_a concern_v the_o general_a doctrine_n of_o bitter_a thing_n nevertheless_o that_o i_o may_v descend_v into_o the_o particular_a nature_n of_o opium_n that_o be_v to_o say_v into_o the_o enumeration_n of_o those_o thing_n that_o distinguish_v it_o from_o other_o bitter_a mixt_n i_o confess_v that_o that_o distinction_n be_v found_v upon_o this_o that_o it_o be_v both_o fixative_a and_o by_o consequence_n febrifugrous_a somniferous_a and_o by_o consequent_a anodin_n we_o must_v inquire_v in_o what_o manner_n it_o act_v upon_o the_o blood_n and_o spirit_n in_o produce_v such_o wonderful_a effect_n for_o a_o more_o clear_a notion_n of_o this_o it_o be_v to_o be_v observe_v that_o the_o particular_a motion_n of_o the_o part_n of_o the_o blood_n wherein_o its_o liquidity_n consist_v become_v of_o necessity_n a_o hindrance_n to_o that_o of_o the_o whole_a mass_n when_o it_o be_v grow_v irregular_a by_o fermentative_a cause_n because_o the_o same_o part_n be_v then_o violent_o agitate_a and_o every_o way_n disperse_v they_o justle_v irregular_o one_o upon_o another_o and_o so_o in_o some_o manner_n resist_v the_o action_n of_o the_o chief_a mover_n of_o the_o blood_n that_o cause_v the_o depravation_n of_o its_o circulary_a motion_n which_o according_a as_o it_o be_v more_o or_o less_o considerable_a cause_v a_o fever_n over_o watch_v particular_a inflammation_n and_o the_o extravasation_n of_o sharp_a and_o bite_v juice_n that_o produce_v all_o kind_n of_o pain_n now_o see_v that_o some_o depravation_n may_v be_v rectify_v by_o bitter_a thing_n as_o i_o have_v demonstrate_v when_o i_o speak_v of_o quinquina_fw-la and_o that_o if_o among_o all_o mixt_n of_o that_o quality_n those_o that_o be_v too_o week_n act_v but_o imperfect_o and_o those_o that_o be_v too_o strong_a irritate_v many_o time_n the_o humour_n in_o stead_n of_o fix_v they_o such_o as_o be_v of_o a_o moderate_a force_n be_v of_o greature_n virtue_n than_o other_o it_o be_v not_o strange_a if_o opium_n which_o be_v but_o moderate_o bitter_a so_o efficacious_o restore_v to_o the_o blood_n the_o uniformity_n of_o its_o motion_n and_o by_o consequent_a that_o pleasant_a tranquillity_n that_o charm_v we_o a_o sleep_n and_o ease_v our_o pain_n but_o in_o as_o much_o as_o there_o be_v inflammation_n or_o if_o one_o may_v say_v so_o fever_n that_o be_v peculiar_a to_o every_o part_n of_o the_o body_n and_o that_o because_o of_o disquietness_n and_o application_n to_o study_n and_o business_n the_o head_n be_v frequent_o subject_a to_o such_o which_o cause_v watch_n and_o which_o seem_v rather_o to_o proceed_v from_o the_o irritation_n of_o the_o spirit_n than_o the_o depravation_n of_o the_o motion_n of_o the_o blood_n it_o must_v indeed_o be_v conclude_v that_o opium_n which_o so_o quick_o rectify_v that_o disorder_n have_v some_o property_n which_o be_v not_o common_a to_o other_o bitter_a medecine_n but_o this_o be_v not_o hard_a to_o be_v explain_v for_o suppose_v that_o all_o or_o almost_o all_o the_o drogue_n of_o that_o quality_n have_v the_o virtue_n to_o rally_v reunite_v and_o fix_v the_o part_n of_o the_o liquor_n of_o our_o body_n in_o which_o they_o be_v diffuse_v it_o be_v sufficient_a that_o opium_n above_o all_o other_o bitter_a medicine_n have_v as_o many_o volatile_a part_n as_o be_v needful_a to_o make_v those_o part_n wherein_o its_o bitterness_n and_o virtue_n of_o fix_v liquid_n do_v consist_v to_o be_v convey_v from_o the_o stomach_n to_o the_o brain_n that_o by_o mean_n of_o that_o sublimation_n they_o may_v have_v occasion_n of_o act_v upon_o the_o extravasated_a liquor_n and_o consequent_o upon_o those_o that_o be_v appoint_v for_o retain_v and_o hinder_v the_o dissipation_n of_o the_o animal_n spirit_n who_o impetuous_a motion_n cause_v watch_v as_o their_o calm_a and_o stillness_n produce_v sleep_v but_o to_o speak_v somewhat_o more_o intelligible_o upon_o this_o subject_a