milk_n which_o be_v a_o very_a fluid_fw-la body_n into_o cheese_n which_o be_v a_o very_a firm_a and_o fix_a one_o agree_v very_o well_o to_o solve_v the_o phaenomena_n of_o that_o disease_n for_o it_o be_v more_o than_o probable_a that_o the_o plague_n kill_v by_o coagulate_v the_o blood_n and_o render_v it_o unfit_a for_o circulation_n for_o the_o spot_n or_o token_n seem_v to_o be_v nothing_o else_o but_o quar_z flake_n of_o it_o which_o be_v thrust_v out_o at_o the_o end_n of_o the_o artery_n there_o stick_v can_v no_o more_o enter_v into_o the_o mouth_n of_o thâ_n vein_n than_o milk_n when_o it_o be_v turn_v ãâã_d cheese_n can_v pass_v through_o a_o streiner_n the_o definition_n which_o m._n n._n give_v we_o iâ_n this_o chapter_n of_o the_o cause_n of_o disease_n i_o think_v be_v very_o pretty_a where_o he_o tell_v we_o that_o the_o cause_n of_o all_o disease_n 199._o me._n med._n p._n 199._o be_v a_o certain_a putrefaction_n secret_o lurk_v among_o the_o hiddââ_n recess_n of_o the_o humour_n this_o definition_n ãâã_d dare_v swear_v for_o he_o be_v his_o own_o though_o he_o have_v the_o face_n to_o fasten_v it_o upon_o the_o vnanimous_a consent_n of_o physician_n for_o by_o its_o being_n most_o unintelligible_a fustian_n i_o know_v it_o to_o be_v of_o the_o same_o wofe_n and_o thread_n with_o the_o rest_n of_o medela_fw-la chap._n vi_o i_o have_v in_o the_o forego_n chapter_n prove_v at_o large_a that_o the_o scurvy_a be_v a_o disease_n ancient_o endemial_a to_o the_o northern_a part_n of_o the_o world_n i_o have_v allow_v a_o notable_a disparity_n to_o be_v between_o the_o blood_n of_o the_o inhabitant_n of_o the_o region_n subject_a to_o this_o disease_n and_o that_o of_o those_o person_n who_o breathe_v the_o air_n where_o the_o ancient_n live_v and_o make_v their_o observation_n upon_o disease_n yet_o be_v not_o the_o difference_n so_o considerable_a but_o that_o a_o rational_a physician_n may_v make_v admirable_a use_n of_o much_o of_o their_o method_n and_o medicine_n in_o the_o cure_n of_o disease_n in_o these_o climate_n and_o even_o in_o such_o case_n where_o the_o scurvy_a bear_v a_o considerable_a share_n in_o the_o complication_n and_o as_o to_o vermination_n i_o have_v demonstrate_v that_o worm_n be_v more_o often_o the_o effect_n than_o cause_n of_o disease_n that_o their_o production_n in_o humane_a and_o other_o natural_a body_n be_v no_o less_o frequent_a and_o observable_a in_o former_a time_n than_o we_o and_o that_o from_o they_o so_o great_a a_o change_n in_o all_o disease_n as_o to_o make_v void_a all_o the_o practice_n and_o medicine_n of_o the_o ancient_n can_v by_o no_o mean_n be_v infer_v it_o be_v confess_v that_o the_o french_a pox_n be_v of_o late_o come_v in_o upon_o we_o from_o america_n but_o m._n n._n have_v not_o in_o the_o least_o prove_v that_o it_o have_v so_o taint_v and_o infect_v the_o stock_n and_o nature_n of_o mankind_n as_o to_o render_v all_o disease_n incident_a to_o humane_a body_n 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superstructure_n be_v demolish_v stable_n and_o unshaken_a and_o though_o it_o must_v be_v confess_v that_o the_o physiology_n and_o pathology_n of_o the_o ancient_n be_v very_o insufficient_a to_o satisfy_v a_o inquire_a man_n concern_v the_o true_a cause_n of_o disease_n and_o their_o symptom_n yet_o much_o of_o the_o method_n certain_o be_v not_o ground_v upon_o they_o but_o be_v long_o in_o use_n before_o those_o notion_n of_o cause_n be_v invent_v the_o learned_a dr._n feb._n willis_n de_fw-fr feb._n willis_n speak_v much_o to_o this_o purpose_n in_o his_o preface_n before_o his_o book_n de_fw-fr febribus_fw-la he_o tell_v we_o that_o in_o the_o cure_n of_o fever_n some_o indication_n ancient_o receive_v do_v in_o this_o age_n stand_v firm_a and_o aught_o to_o be_v observe_v to_o the_o world_n end_n and_o that_o they_o be_v not_o found_v upon_o the_o precept_n of_o school_n but_o upon_o experience_n the_o mistress_n and_o teacher_n of_o the_o art_n of_o physic_n and_o that_o 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and_o experience_n nor_o these_o corrupt_a reason_n seem_v to_o be_v a_o most_o absolute_a and_o complete_a physician_n now_o if_o it_o be_v true_a as_o this_o excellent_a philosopher_n and_o physician_n affirm_v that_o much_o of_o the_o method_n and_o many_o of_o the_o precept_n of_o physic_n do_v and_o will_v always_o continue_v firm_a and_o useful_a because_o they_o be_v not_o establish_v upon_o fantastical_a notion_n such_o as_o be_v the_o author_n be_v of_o medela_fw-la but_o upon_o unerring_a experience_n no_o less_o will_v those_o medicine_n which_o the_o constant_a trial_n of_o the_o world_n have_v recommend_v as_o effectual_a remain_v serviceable_a to_o physician_n before_o such_o as_o be_v imagine_v by_o the_o touchy_a head_n of_o m._n n._n or_o any_o other_o whimsical_a inventor_n of_o secret_n and_o remedy_n for_o i_o have_v already_o prove_v at_o large_a in_o the_o first_o chapter_n that_o the_o materia_fw-la medica_fw-la be_v whole_o found_v upon_o experience_n that_o 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hysterical_a fit_n and_o some_o even_o after_o so_o large_a haemorrhage_n that_o there_o have_v be_v more_o reason_n to_o believe_v they_o have_v not_o blood_n enough_o leave_v to_o maintain_v the_o circulation_n than_o to_o suspect_v the_o lung_n and_o heart_n can_v be_v oppress_v with_o it_o riverius_n have_v a_o observation_n of_o a_o maid_n 94._o river_n ob_fw-la cent_n 1._o ob_fw-la 94._o who_o have_v her_o menstruous_a flux_n in_o so_o violent_a a_o manner_n that_o in_o the_o space_n of_o two_o hour_n she_o void_v four_o or_o five_o pint_n of_o blood_n fall_v into_o so_o terrible_a a_o fit_a of_o the_o mother_n that_o she_o lie_v without_o speech_n as_o one_o dead_a and_o yet_o have_v her_o eye_n open_a and_o show_v with_o her_o hand_n that_o she_o be_v strangle_v these_o and_o other_o reason_n seem_v to_o argue_v that_o the_o animal_n constitution_n i_o use_v dr._n glysson_n word_n be_v primary_o affect_v in_o this_o disease_n 19_o glisson_n de_fw-fr râchid_n p._n 19_o and_o the_o heart_n and_o lung_n only_o secondary_o and_o by_o consent_n and_o that_o the_o disorder_n of_o the_o vital_a part_n as_o well_o as_o the_o rest_n of_o hysterical_a symptons_n be_v mere_o convulsive_a motion_n consonant_a to_o this_o dr._n willis_n in_o his_o most_o admirable_a treatise_n of_o the_o brain_n &_o nerve_n give_v a_o excellent_a account_n how_o the_o lung_n come_v to_o be_v affect_v in_o hysterical_a and_o hypochondriacal_a paroxysm_n in_o these_o word_n si_fw-mi quando_fw-la nervos_fw-la pneumonicos_fw-la à _fw-la causa_fw-la morbifica_fw-la affectiones_fw-la spasmodicae_n afflixerint_fw-la ita_fw-la ut_fw-la motibus_fw-la inordinatis_fw-la convulsi_fw-la arterias_fw-la &_o venas_fw-la quas_fw-la amplectuntur_fw-la perperam_fw-la constringant_fw-la aut_fw-la huc_fw-la illuc_fw-la contrahant_fw-la propterea_fw-la sanguis_fw-la aut_fw-la pulmonibus_fw-la nimis_fw-la exulans_fw-la eos_fw-la flaccescere_fw-la ac_fw-la in_o se_fw-la concidere_fw-la facit_fw-la adeo_fw-la ut_fw-la aerem_fw-la copiose_fw-la attrahentes_fw-la ipsum_fw-la haud_fw-la facile_fw-la reddant_fw-la vel_fw-la quod_fw-la crebrius_fw-la usu_fw-la venit_fw-la sanguis_fw-la intra_fw-la pulmones_fw-la detentus_fw-la ibidemque_fw-la stagnans_fw-la eos_fw-la infercit_fw-la ac_fw-la diu_fw-la rigidos_fw-la tenet_fw-la ut_fw-la aerem_fw-la inspirare_fw-la nequeant_fw-la vtriusque_fw-la generis_fw-la symptomata_n in_fw-la affectibus_fw-la hystericis_fw-la &_o quibusdam_fw-la hypochondriacis_n passim_fw-la contingunt_fw-la quinimo_fw-la interdum_fw-la ipsa_fw-la bronchia_fw-la pari_fw-la nervorum_fw-la spasmo_fw-la convelluntur_fw-la ac_fw-la in_o motu_fw-la svo_fw-la praepediuntur_fw-la quo_fw-la minus_fw-la debito_fw-la modo_fw-la aerem_fw-la inspirent_fw-la exspirentque_fw-la prout_fw-la in_o paroxysmis_fw-la asthmaticis_fw-la cernitur_fw-la cujusmodi_fw-la affectus_fw-la saepenumero_fw-la a_o nervorum_fw-la vitio_fw-la sine_fw-la insita_fw-la quavis_fw-la pulmonum_fw-la dyserasia_fw-la producuntur_fw-la 24._o willis_n nervorum_fw-la descrip_n c._n 24._o in_o the_o same_o chapter_n he_o acquaint_v we_o how_o the_o affection_n and_o motion_n of_o the_o heart_n be_v produce_v by_o the_o influence_n of_o the_o animal_n spirit_n through_o the_o intercostal_n and_o eight_o pair_v of_o nerve_n and_o that_o the_o tremble_n and_o disorderly_a vibration_n of_o the_o heart_n which_o evident_o differ_v from_o its_o pulsifick_a motion_n be_v cause_v from_o the_o violent_a succussion_n and_o convulsion_n of_o the_o pericardium_n to_o evince_v the_o necessity_n of_o the_o influx_n of_o the_o animal_n spirit_n to_o maintain_v the_o motion_n of_o the_o heart_n he_o tell_v we_o that_o he_o have_v often_o make_v this_o experiment_n in_o dog_n when_o they_o be_v alive_a have_v open_v the_o skin_n about_o the_o neck_n he_o tie_v both_o the_o trunk_n of_o the_o par_fw-fr vagum_fw-la with_o very_o strict_a ligature_n upon_o which_o the_o dog_n seem_v to_o be_v stuned_a lose_v whole_o his_o 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notable_o to_o vellicate_a the_o extremity_n of_o the_o neru_n &_o affect_v they_o so_o strong_o as_o to_o draw_v into_o consent_n the_o whole_a system_n or_o else_o to_o put_v the_o animal_n spirit_n in_o the_o brain_n into_o so_o great_a a_o confusion_n and_o disorder_n as_o to_o disturb_v their_o constant_a and_o regular_a irradiation_n and_o influx_n into_o the_o bowel_n and_o other_o part_n of_o the_o body_n or_o whatever_o cause_n be_v apt_a to_o render_v the_o nervous_a juice_n which_o be_v the_o vehicle_n of_o the_o spirit_n sharp_a and_o pungent_a and_o apt_a to_o irritate_fw-la and_o provoke_v the_o fiber_n in_o its_o passage_n the_o ancient_n reckon_v the_o seed_n retain_v in_o the_o genital_a part_n in_o too_o great_a a_o quantity_n as_o one_o of_o the_o principal_a cause_n of_o these_o affection_n and_o that_o we_o may_v the_o better_o understand_v how_o that_o be_v able_a to_o put_v the_o animal_n spirit_n and_o nerve_n into_o disorderly_a motion_n it_o will_v not_o be_v impertinent_a to_o consider_v the_o nature_n of_o it_o the_o seed_n or_o geniture_n seem_v to_o consist_v of_o salt_n sulphur_n and_o a_o great_a quantity_n of_o spirit_n for_o these_o active_a principle_n be_v only_o able_a to_o perform_v that_o wonderful_a work_n of_o generation_n in_o that_o secret_a shop_n of_o nature_n the_o womb._n it_o may_v be_v prove_v by_o sundry_a experiment_n that_o a_o nitro-sulphureous_a spirit_n be_v the_o author_n of_o all_o generation_n as_o well_o in_o vegetable_n as_o animal_n the_o account_n which_o that_o eminent_o learned_a person_n d._n ent_n give_v of_o the_o production_n of_o thing_n in_o his_o apology_n for_o the_o circulation_n against_o parisanus_n be_v very_o much_o to_o this_o purpose_n apol._n eat_v apol._n terra_fw-la &_o aqua_fw-la say_v he_o matery_n sunt_fw-la rerum_fw-la naturalium_fw-la in_fw-la quibus_fw-la seu_fw-la uteris_fw-la diversa_fw-la rerum_fw-la gignendarum_fw-la semina_fw-la sive_fw-la spiritus_fw-la delitescunt_fw-la 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wrought_v very_o gentle_o with_o she_o but_o as_o soon_o as_o the_o work_n be_v over_o after_o her_o last_o vomit_n she_o fall_v into_o a_o fit_a of_o the_o muther_n it_o may_v be_v expect_v that_o i_o shall_v now_o give_v a_o account_n of_o every_o particular_a symptom_n which_o belong_v to_o this_o disease_n but_o not_o design_v to_o make_v a_o exact_a treatise_n of_o it_o in_o this_o place_n i_o must_v recommend_v to_o the_o reader_n the_o consideration_n of_o these_o cause_n which_o i_o have_v mention_v or_o any_o other_o which_o he_o can_v imagine_v powerful_a enough_o to_o make_v disorder_n in_o the_o animal_n spirit_n and_o convulsion_n in_o the_o nervous_a part_n and_o as_o for_o the_o particular_a consent_n &_o correspondency_n of_o one_o part_n with_o another_o how_o distemper_n begin_v in_o one_o part_n manifest_v themselves_o in_o another_o far_o remote_a i_o refer_v he_o to_o dr._n willis_n his_o most_o learned_a treatise_n of_o the_o brain_n and_o nerve_n and_o to_o the_o 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asthmatical_a rise_n and_o stop_n to_o convulsion_n of_o the_o nerve_n and_o not_o to_o vicious_a and_o malignant_a vapour_n raise_v in_o the_o low_a belly_n especial_o about_o the_o spleen_n in_o the_o stomach_n 50._o mâd._n mâd._n p_o 49._o &_o 50._o and_o about_o the_o midriff_n and_o in_o the_o cavity_n of_o the_o omentum_fw-la nor_o to_o the_o play_v of_o the_o scorbutic_a malignant_a vapour_n up_o through_o the_o vein_n and_o artery_n to_o the_o lung_n and_o by_o communication_n to_o the_o heart_n which_o account_n may_v be_v well_o enough_o tolerate_v in_o sennertus_n but_o be_v by_o no_o mean_n to_o be_v endure_v in_o m._n n._n who_o pretend_v so_o much_o to_o the_o new_a discovery_n in_o physic_n and_o undertake_v to_o demolish_v and_o overthrow_v all_o the_o old_a writer_n and_o yet_o aggree_v with_o they_o in_o their_o gross_a mistake_n and_o now_o have_v clear_o prove_v that_o the_o disease_n of_o this_o present_a age_n be_v not_o so_o much_o change_v and_o of_o another_o 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firmness_n inasmuch_o as_o a_o dry_a body_n be_v upon_o that_o score_n the_o more_o firm_a for_o be_v void_a of_o all_o moisture_n and_o now_o i_o can_v see_v why_o these_o four_o first_o quality_n as_o they_o be_v term_v shall_v be_v exclude_v from_o have_v a_o share_n in_o the_o number_n of_o the_o cause_n of_o disease_n since_o they_o be_v notable_o active_a especial_o the_o three_o first_o modification_n of_o matter_n and_o not_o only_o apt_a to_o excite_v various_a motion_n and_o cause_n as_o well_o new_a combination_n as_o dissolution_n of_o body_n in_o the_o great_a world_n but_o also_o powerful_o to_o alter_v the_o microcosm_n and_o produce_v fundry_a different_a symptom_n in_o relation_n to_o the_o motion_n and_o harmony_n of_o the_o humane_a engin._n in_o the_o next_o place_n though_o it_o be_v utter_o untrue_a that_o there_o be_v in_o the_o vessel_n four_o distinct_a humour_n but_o whatsoever_o be_v contain_v in_o the_o artery_n and_o vein_n be_v either_o the_o stale_a deflagrate_v blood_n or_o the_o alimentary_a juice_n fresh_a come_v into_o the_o vessel_n or_o else_o the_o serum_fw-la or_o whey_n return_v by_o the_o lymphaticks_n or_o else_o some_o particle_n of_o nitre_n and_o other_o body_n receive_v in_o by_o the_o lung_n and_o mouth_n of_o the_o vein_n from_o the_o ambient_fw-la and_o though_o the_o blood_n differ_v in_o several_a person_n only_o as_o to_o the_o abundance_n or_o defect_n of_o natural_a heat_n yet_o be_v man_n not_o improper_o say_v to_o be_v of_o a_o melancholic_a choleric_a or_o some_o other_o temperament_n inasmuch_o as_o by_o how_o much_o the_o more_o vigorous_a or_o remiss_a the_o natural_a heat_n be_v in_o their_o bowel_n and_o entrail_n by_o so_o much_o the_o more_o weak_o or_o powerful_o concoction_n be_v perform_v and_o consequent_o the_o blood_n apt_a to_o be_v overcharge_v either_o with_o stale_a and_o adust_a or_o else_o crude_a and_o phlegmatic_a excrement_n in_o which_o respect_n the_o person_n either_o way_n dispose_v be_v not_o improper_o say_v to_o be_v of_o a_o phlegmatic_a or_o choleric_a temper_n and_o if_o the_o adust_a or_o raw_a excrement_n be_v not_o right_o and_o due_o separate_v out_o of_o the_o mass_n by_o the_o effervenscy_n of_o the_o blood_n i_o see_v no_o reason_n why_o i_o may_v not_o say_v that_o a_o man_n abound_v with_o a_o melancholic_a choleric_a or_o phlegmatic_a humour_n and_o if_o so_o the_o notion_n about_o pharmacy_n aim_v at_o a_o evacuation_n or_o else_o alteration_n of_o these_o humour_n be_v not_o frame_v amiss_o nor_o whatever_o m._n n._n argue_v to_o the_o contrary_a without_o very_o good_a reason_n for_o i_o suppose_v it_o alter_v not_o much_o the_o case_n as_o to_o practise_v whether_o a_o man_n suppose_v that_o there_o be_v too_o great_a a_o redundancy_n of_o one_o of_o the_o humour_n in_o the_o blood_n or_o whether_o which_o be_v the_o right_a notion_n he_o apprehend_v the_o blood_n deprave_v either_o with_o phlegmatic_a and_o raw_a juice_n or_o the_o bilious_a excrement_n consist_v of_o salt_n and_o sulphur_n or_o the_o melancholic_a in_o which_o the_o caput_fw-la mortuum_fw-la or_o earthy_a part_n be_v most_o predominant_a for_o either_o of_o these_o notion_n will_v direct_v we_o when_o the_o blood_n be_v unable_a to_o fine_a its_o self_n to_o assist_v it_o with_o those_o alterative_n which_o time_n and_o experience_n have_v recommend_v to_o we_o as_o proper_a in_o those_o case_n and_o those_o purger_n which_o have_v be_v long_o observe_v more_o particular_o to_o make_v a_o separation_n either_o of_o the_o pituitous_a choleric_a or_o melancholic_a part_n of_o the_o blood_n for_o though_o it_o be_v irrational_a to_o think_v that_o purger_n do_v with_o a_o certain_a knowledge_n or_o choice_n lay_v hold_v of_o one_o humour_n rather_o than_o another_o yet_o be_v that_o distinction_n of_o purger_n into_o chologoga_n phlegmagoga_n melanagoga_n and_o hydragoga_n of_o very_o good_a use_n and_o found_v upon_o observation_n and_o experience_n inasmuch_o as_o these_o several_a purger_n by_o cause_v very_o different_a fermentation_n and_o various_o agitate_v the_o particle_n of_o the_o blood_n may_v with_o very_o good_a reason_n cause_n different_a separation_n and_o so_o one_o purger_n to_o evacuate_v that_o sort_n of_o excrement_n barm_n or_o lee_n which_o another_o can_v and_o in_o this_o matter_n i_o do_v not_o find_v that_o the_o improvement_n which_o have_v be_v make_v in_o the_o theory_n of_o physic_n have_v much_o alter_v the_o practice_n for_o the_o indication_n for_o purge_v be_v not_o found_v upon_o the_o notion_n of_o the_o four_o humour_n but_o upon_o long_a observation_n that_o when_o distemper_n discover_v themselves_o by_o such_o and_o such_o sign_n the_o body_n be_v to_o be_v empty_v and_o by_o frequent_a trial_n one_o purger_n as_o especial_o hellebor_n in_o melancholy_n be_v find_v more_o essectual_a than_o