of_o man_n because_o of_o its_o ill_a effect_n lavish_o use_v therefore_o none_o can_v argue_v from_o that_o that_o opium_n diminish_v or_o disable_v the_o spirit_n any_o more_o than_o wine_n or_o bread_n do_v a_o surfeit_n of_o which_o be_v most_o dangerous_a omnis_fw-la repletio_fw-la mala_fw-la panis_n vero_fw-la pessima_fw-la &_o corruptio_fw-la optimi_fw-la est_fw-la pessima_fw-la that_o be_v all_o repletion_n be_v bad_a but_o that_o of_o bread_n be_v the_o worst_a and_o the_o corruption_n of_o the_o best_a be_v the_o worst_a the_o short_a be_v this_o wine_n and_o opium_n agree_v in_o all_o their_o effect_n save_v such_o as_o be_v consequence_n of_o their_o different_a accident_n as_o the_o quantity_n of_o wine_n that_o must_v be_v use_v to_o cause_v the_o same_o effect_n with_o a_o little_a opium_n and_o wine_n have_v be_v ferment_v and_o opium_n as_o may_v be_v show_v have_v some_o crude_a and_o viscid_a rosin_n in_o it_o which_o sometime_o stick_v to_o the_o crusta_fw-la carnosa_fw-la etc._n etc._n of_o the_o stomach_n whence_o it_o happen_v that_o wine_n load_v one_o more_o heat_v more_o and_o be_v more_o troublesome_a upon_o those_o account_n and_o that_o opium_n offend_v the_o stomach_n often_o even_o in_o a_o moderate_a do_v cause_v vomit_n hiccough_n anxiety_n distress_n at_o stomach_n deliquium_n etc._n etc._n because_o of_o the_o indigestible_a rosin_n stick_v to_o the_o side_n of_o the_o most_o sensile_a stomach_n as_o i_o shall_v far_o prove_v hereafter_o by_o god_n help_n show_v very_o easy_a way_n and_o mean_n to_o separate_v that_o rosin_n and_o so_o make_v it_o as_o safe_a and_o less_o troublesome_a as_o it_o be_v more_o effectual_a than_o wine_n opium_n can_v diminish_v or_o disable_v the_o spirit_n because_o as_o have_v be_v prove_v it_o send_v no_o part_n fume_v or_o effluvium_fw-la to_o the_o brain_n or_o animal_n spirit_n to_o cause_v such_o bad_a effect_n while_o it_o be_v at_o stomach_n yet_o do_v it_o produce_v they_o while_o it_o be_v there_o for_o as_o the_o vaporarians_n themselves_o and_o indeed_o all_o man_n allow_v there_o can_v be_v no_o destruction_n without_o contact_n sanctorius_n do_v well_o and_o true_o observe_v by_o the_o help_n of_o his_o static_o that_o nothing_o cause_v liberal_a perspiration_n but_o it_o raise_v the_o spirit_n it_o be_v most_o certain_a that_o nothing_o in_o nature_n open_v the_o pore_n and_o cause_n perspiration_n more_o than_o opium_n therefore_o nothing_o shall_v according_a to_o his_o observation_n elevate_v the_o spirit_n more_o and_z indeed_o nothing_o do_v as_o appear_v by_o all_o that_o have_v be_v say_v and_o will_v yet_o more_o plain_o appear_v loss_n of_o memory_n by_o opium_n as_o some_o argue_v be_v not_o so_o much_o a_o loss_n of_o spirit_n as_o lanity_n of_o the_o brain_n for_o people_n in_o drink_n do_v not_o want_v spirit_n but_o there_o be_v a_o great_a relaxation_n of_o the_o brain_n and_o its_o membrane_n and_o of_o the_o whole_a jenus_fw-la 〈◊〉_d which_o relaxation_n cause_v a_o soft_a loose_a and_o labile_fw-la brain_n that_o like_o liquid_a thing_n retain_v no_o impression_n beside_o that_o i_o shall_v god_n will_v show_v you_o hereafter_o that_o impression_n can_v be_v so_o well_o make_v upon_o the_o sensitive_a soul_n by_o the_o animal_n spirit_n upon_o relaxation_n of_o the_o sensible_a part_n as_o in_o sleep_n etc._n etc._n for_o a_o very_a plain_a mechanical_a reason_n to_o be_v show_v in_o due_a time_n thus_o have_v i_o by_o the_o assistance_n of_o its_o maker_n who_o best_o know_v it_o clear_v opium_n from_o the_o false_a aspersion_n of_o a_o extreme_a cold_a quality_n and_o parcotick_a fume_n both_o which_o be_v common_o call_v venomous_a fatal_a and_o by_o all_o the_o ill_a name_n imaginable_a but_o as_o good_a luck_n be_v they_o abuse_v nothing_o because_o it_o be_v manifest_a that_o there_o be_v no_o such_o thing_n nor_o have_v it_o any_o quality_n by_o which_o it_o diminish_v or_o disable_v the_o spirit_n as_o be_v most_o evident_a from_o the_o premise_n so_o that_o all_o that_o have_v be_v say_v of_o opium_n by_o way_n of_o hypothesis_n to_o explain_v its_o effect_n depend_v upon_o its_o diminish_n or_o disable_n the_o spirit_n by_o a_o cold_a quality_n or_o fume_n be_v come_v to_o nothing_o i_o wish_v it_o have_v be_v as_o innocent_a chap._n xii_o show_v what_o must_v be_v the_o true_a cause_n of_o the_o operation_n of_o opium_n all_o the_o general_a foundation_n upon_o which_o author_n either_o ancient_a or_o modern_a erect_v their_o several_a hypothesise_n concern_v the_o operation_n of_o opium_n have_v as_o manifest_o appear_v no_o real_a existence_n what_o enchant_a castle_n in_o the_o air_n or_o vain_a phantasm_n must_v their_o structure_n be_v and_o how_o like_a delude_a wizzard_n must_v they_o appear_v while_o they_o seem_v to_o take_v high_a flight_n and_o glorious_a prospect_n of_o cause_n that_o have_v no_o reality_n thus_o be_o i_o leave_v utter_o destitute_a of_o either_o foundation_n or_o model_n unless_o i_o find_v out_o that_o and_o frame_v this_o which_o i_o hope_v may_v be_v easy_o do_v because_o the_o cloudy_a supposition_n of_o vapour_n have_v vanish_v away_o there_o now_o remain_v but_o two_o way_n by_o which_o a_o internal_a medicament_n can_v operate_v viz._n 1._o as_o a_o alterative_a of_o the_o blood_n etc._n etc._n or_o 2._o as_o affect_v the_o sense_n of_o feel_v either_o grievous_o as_o vomit_n purger_n etc._n etc._n or_o pleas_o as_o cordial_n generous_a wine_n titillate_v amphrodisiack_n comfortable_a warmth_n anodynes_n and_o such_o like_a that_o please_v the_o nerve_n and_o membrane_n which_o way_n of_o operate_n be_v too_o little_o observe_v by_o physician_n though_o they_o take_v great_a notice_n of_o the_o operation_n of_o thing_n by_o grievous_a sensation_n as_o irritative_n to_o vomit_n purge_v salivate_a etc._n etc._n by_o their_o acrimony_n whereas_o the_o pleaser_n of_o sensation_n which_o must_v as_o contrary_n have_v contrary_a operation_n be_v little_o regard_v or_o think_v of_o 1._o opium_n do_v not_o operate_v as_o a_o alterative_a of_o the_o blood_n etc._n etc._n first_o because_o it_o operate_v while_o it_o be_v at_o stomach_n or_o at_o least_o before_o it_o arrive_v at_o the_o blood_n which_o manifest_o appear_v several_a way_n as_o 1._o because_o it_o often_o operate_v in_o a_o liquid_a form_n in_o few_o minute_n and_o very_o common_o in_o a_o quarter_n of_o a_o hour_n in_o which_o time_n it_o must_v be_v at_o stomach_n or_o at_o least_o far_o from_o arrive_v at_o the_o blood_n 2._o because_o it_o have_v be_v very_o often_o vomit_v up_o after_o it_o have_v operate_v and_o produce_v its_o usual_a effect_n for_o 1_o 2_o 3_o 4_o 5_o 6_o 8_o 10_o and_o sometime_o more_o hour_n as_o evident_o appear_v by_o the_o smell_n colour_n taste_v etc._n etc._n of_o what_o be_v vomit_v and_o by_o its_o operation_n cease_v after_o such_o vomit_v of_o which_o common_a experience_n and_o author_n do_v inform_v we_o see_v helmont_n ius_n duumvir_fw-la 62._o where_o he_o tell_v of_o opium_n operate_a at_o night_n and_o vomit_v up_o next_o morning_n 3._o it_o be_v bare_a cause_v vomit_v after_o it_o have_v operate_v for_o a_o good_a while_n be_v of_o itself_o though_o its_o taste_n smell_v etc._n etc._n do_v not_o discover_v it_o a_o infallible_a argument_n of_o its_o operate_n while_o it_o be_v at_o stomach_n for_o it_o be_v against_o all_o reason_n to_o imagine_v that_o thing_n shall_v irritate_fw-la it_o to_o vomit_n after_o they_o be_v go_v into_o the_o blood_n and_o not_o do_v it_o while_o they_o be_v in_o the_o stomach_n itself_o as_o all_o vomitory_n do_v the_o reason_n why_o it_o stay_v so_o long_o at_o stomach_n be_v 1._o it_o be_v indigestibleness_n which_o plain_o appear_v by_o stool_n urine_n and_o sweat_v smell_v of_o it_o when_o take_v in_o any_o considerable_a quantity_n all_o the_o coction_n digestion_n circulation_n etc._n etc._n that_o it_o pass_v in_o the_o body_n signify_v very_o little_a to_o it_o which_o its_o cause_v itch_n in_o the_o skin_n and_o affect_v the_o venereal_a membrane_n after_o its_o pass_v the_o blood_n do_v also_o argue_v 2._o the_o clamminess_n of_o its_o resinous_a part_n stick_v to_o the_o stomach_n cause_n as_o i_o shall_v plain_o prove_v hereafter_o its_o long_a stay_n in_o it_o for_o if_o the_o rosin_n be_v separate_v from_o it_o it_o will_v not_o then_o make_v such_o a_o long_a stay_n at_o stomach_n as_o i_o have_v often_o experience_v 4._o we_o actual_o feel_v it_o cause_v a_o sense_n of_o pleasure_n at_o stomach_n during_o its_o operation_n therefore_o it_o be_v then_o in_o it_o 5._o it_o have_v be_v carry_v off_o by_o stool_n after_o it_o have_v produce_v its_o usual_a effect_n therefore_o it_o operate_v before_o it_o arrive_v at_o the_o blood_n 6._o all_o observer_n do_v allow_v that_o opium_n operate_v while_o it_o be_v at_o stomach_n
as_o appear_v by_o several_a place_n or_o passage_n of_o the_o premise_n and_o in_o the_o wake_a more_o than_o in_o such_o as_o be_v asleep_a 6._o it_o be_v manifest_a that_o they_o be_v elastic_a by_o their_o spring_v into_o a_o limb_n hold_v up_o or_o down_o and_o that_o with_o such_o force_n as_o to_o cause_v a_o great_a pain_n after_o they_o have_v be_v exclude_v from_o it_o by_o some_o accident_n as_o lean_v or_o press_v too_o hard_o upon_o a_o nerve_n etc._n etc._n for_o neither_o levity_n nor_o gravity_n can_v do_v so_o especial_o both_o up_o and_o down_o as_o be_v say_v nor_o be_v there_o any_o propulsory_a engine_n for_o they_o as_o be_v for_o the_o blond_n therefore_o it_o must_v be_v from_o their_o springiness_n 7._o they_o can_v not_o cause_v brisk_a and_o smart_a tremulous_a motion_n in_o the_o body_n if_o they_o be_v not_o elastic_a for_o such_o can_v be_v conceive_v by_o any_o mean_n without_o it_o but_o there_o be_v several_a brisk_a and_o smart_a tremulous_a motion_n cause_v by_o the_o animal_n spirit_n as_o in_o the_o shivering_n of_o ague_n fit_n fright_v cold_a surprise_v sudden_a or_o exquisite_a pain_n tremor_n of_o the_o hand_n head_z etc._n etc._n in_o old_a age_n in_o some_o conuâ—_n etc._n etc._n therefore_o the_o animal_n spirit_n that_o cause_v they_o be_v elastic_a 8._o muscle_n have_v no_o springiness_n of_o themselves_o when_o the_o animal_n spirit_n be_v exclude_v from_o they_o as_o in_o palsy_n etc._n etc._n but_o all_o muscle_n in_o their_o exertion_n be_v very_o springy_a insomuch_o that_o if_o you_o hold_v any_o of_o they_o back_o or_o restrain_v they_o from_o their_o motion_n and_o again_o sudden_o leave_v they_o at_o liberty_n during_o the_o exertion_n they_o or_o any_o part_n move_v by_o they_o will_v spring_v out_o very_o violent_o as_o in_o flip_v a_o arm_n hold_v back_o etc._n etc._n but_o nothing_o prove_v this_o matter_n better_o than_o the_o tongue_n in_o form_v the_o sound_n of_o the_o letter_n r_n for_o in_o that_o case_n the_o tongue_n after_o it_o be_v put_v in_o tension_n and_o exertion_n be_v sudden_o hit_v against_o the_o inside_n or_o gum_n of_o the_o upper_a tooth_n do_v thereupon_o as_o springy_a body_n use_v to_o do_v fall_v into_o a_o tremulous_a motion_n or_o jar_a that_o cause_v the_o snarl_a sound_n of_o r_n which_o nothing_o but_o springy_a matter_n can_v do_v 9_o be_v they_o not_o springy_a they_o can_v never_o convey_v the_o tremulous_a motion_n of_o sound_n to_o the_o sensitive_a soul_n and_o indeed_o over_o all_o the_o systeme_n of_o the_o nerve_n by_o which_o be_v cause_v as_o may_v be_v prove_v that_o motion_n of_o consent_n call_v dance_v and_o the_o finger_n etc._n etc._n to_o move_v and_o keep_v time_n with_o the_o music_n even_o when_o it_o or_o the_o finger_n be_v not_o as_o much_o as_o think_v of_o because_o the_o animal_n spirit_n have_v the_o same_o capacity_n with_o the_o air_n to_o receive_v and_o convey_v it_o by_o reason_n of_o their_o springiness_n and_o great_a by_o reason_n of_o their_o more_o forcible_a compression_n by_o the_o vigilative_a contraction_n supper_n add_v to_o the_o compression_n of_o the_o air_n under_o which_o they_o be_v as_o well_o as_o the_o air_n itself_o as_o plain_a reason_n tell_v we_o for_o that_o which_o compress_n the_o whole_a body_n must_v needs_o compress_v the_o animal_n spirit_n the_o experiment_n of_o the_o air-pump_n do_v confirm_v the_o same_o 10._o there_o can_v be_v no_o doubt_n but_o the_o animal_n spirit_n be_v nourish_v or_o sustain_v by_o the_o air_n if_o they_o be_v not_o air_n therefore_o they_o be_v elastic_a what_o need_v any_o more_o argument_n when_o several_a of_o the_o former_a be_v demonstrative_a and_o that_o 11._o all_o physician_n and_o philosopher_n that_o i_o know_v of_o do_v allow_v that_o the_o animal_n spirit_n be_v elastic_a second_o it_o be_v requisite_a as_o be_v say_v of_o the_o external_n medium_fw-la that_o they_o shall_v be_v compress_v to_o render_v they_o fit_a to_o convey_v impression_n and_o that_o they_o be_v compress_v be_v evident_a as_o be_v before_o intimate_v 1._o by_o the_o atmosphere_n 2._o by_o the_o vigilative_a contraction_n which_o make_v they_o much_o more_o dispose_v to_o convey_v impression_n than_o the_o external_n medium_fw-la beside_o that_o very_o often_o two_o other_o contradiction_n that_o be_v show_v in_o the_o remain_a part_n of_o this_o chapter_n be_v add_v thereto_o and_o that_o the_o animal_n spirit_n be_v whole_o contain_v in_o pipe_n to_o prevent_v their_o expansion_n and_o that_o of_o the_o narrow_a size_n that_o can_v well_o be_v imagine_v but_o the_o air_n or_o external_n medium_fw-la be_v at_o large_a in_o the_o atmosphere_n so_o that_o all_o the_o impression_n make_v upon_o the_o animal_n spirit_n be_v very_o tight_o close_o and_o smart_o convey_v nor_o have_v they_o but_o a_o little_a way_n to_o pass_v that_o be_v the_o length_n of_o the_o animal_n at_o most_o which_o also_o may_v be_v some_o advantage_n to_o small_a creature_n but_o in_o sleep_n the_o vigilative_a contraction_n be_v lose_v and_o the_o animal_n spirit_n thereupon_o expanded_a all_o impulse_n must_v needs_o be_v carry_v very_o faint_o both_o because_o the_o organ_n or_o membrane_n be_v indispose_v by_o relaxation_n and_o the_o animal_n spirit_n by_o expansion_n upon_o that_o relaxation_n for_o want_v of_o due_a compression_n to_o fit_v they_o thus_o have_v you_o after_o many_o vain_a inquiry_n the_o true_a mechanical_a cause_n of_o the_o difference_n of_o sensation_n sleep_v and_o wake_v and_o the_o plain_a reason_n why_o our_o motion_n be_v so_o feeble_a in_o sleep_n viz._n because_o the_o animal_n spirit_n have_v lose_v much_o of_o their_o force_n springiness_n etc._n etc._n for_o want_n of_o due_a compression_n by_o reason_n of_o the_o relaxation_n of_o all_o the_o vessel_n that_o include_v the_o spirit_n three_o it_o be_v in_o some_o measure_n requisite_a that_o the_o animal_n spirit_n shall_v have_v a_o homogeneous_a continuity_n as_o be_v show_v by_o the_o analogy_n of_o the_o external_n medium_fw-la which_o do_v not_o convey_v impression_n as_o well_o in_o the_o heat_n of_o the_o day_n as_o in_o the_o night_n or_o after_o sunset_n because_o its_o part_n be_v more_o discontinue_v and_o disgregated_a by_o the_o particle_n of_o heat_n fume_n etc._n etc._n in_o the_o day_n time_n nay_o if_o thing_n be_v discontinue_v they_o never_o carry_v impression_n so_o well_o though_o place_v contiguous_o afterward_o thus_o a_o long_a tree_n that_o convey_v sound_n so_o exact_o from_o one_o end_n to_o the_o other_o while_o all_o be_v continue_v and_o in_o one_o piece_n will_v not_o convey_v the_o sound_n so_o well_o if_o it_o be_v cut_v into_o many_o piece_n though_o they_o be_v afterward_o put_v close_o one_o to_o the_o other_o as_o to_o this_o matter_n of_o continuity_n in_o the_o animal_n spirit_n see_v it_o do_v not_o much_o concern_v we_o and_o that_o people_n in_o a_o state_n of_o health_n be_v suppose_v to_o have_v it_o and_o that_o it_o be_v not_o our_o business_n here_o to_o enter_v upon_o the_o consideration_n of_o nervous_a distemper_n i_o need_v not_o use_v any_o more_o word_n about_o it_o but_o that_o if_o it_o any_o way_n happen_v to_o be_v discontinue_v as_o either_o by_o the_o penury_n thereof_o that_o they_o do_v not_o quite_o fill_v all_o part_n of_o their_o vessel_n or_o any_o matter_n intercept_n their_o part_n or_o that_o the_o vessel_n shall_v be_v so_o relax_v or_o widen_v that_o the_o animal_n spirit_n can_v so_o well_o fill_v they_o up_o etc._n etc._n such_o cause_n must_v destroy_v or_o lessen_v sensation_n though_o the_o bare_a mix_n of_o fume_n with_o they_o will_v not_o consider_v the_o shortness_n of_o the_o way_n that_o impression_n be_v carry_v in_o animal_n much_o alter_v the_o case_n as_o you_o find_v fume_n in_o the_o air_n do_v not_o much_o hinder_a sound_n at_o the_o distance_n of_o a_o yard_n or_o two_o wherein_o it_o be_v insensible_a to_o common_a observer_n at_o least_o so_o that_o if_o some_o fume_n from_o a_o grain_n or_o two_o of_o opium_n do_v mingle_v with_o the_o animal_n spirit_n it_o will_v not_o cause_v a_o sensible_a difference_n of_o feel_v in_o the_o short_a space_n of_o the_o length_n of_o a_o animal_n but_o i_o have_v prove_v that_o no_o such_o fume_v from_o the_o opium_n mix_v with_o they_o therefore_o need_v say_v no_o more_o of_o this_o matter_n v._o the_o office_n or_o business_n of_o the_o sensitive_a soul_n in_o the_o oeconomy_n of_o sensation_n be_v to_o perceive_v the_o impression_n convey_v to_o he_o by_o the_o animal_n spirit_n that_o he_o may_v if_o he_o find_v they_o disagreeable_a bestir_v himself_o in_o defence_n of_o the_o animal_n first_o it_o be_v requisite_a he_o shall_v attend_v to_o all_o impression_n offer_v he_o by_o the_o animal_n spirit_n otherwise_o
impression_n of_o great_a concernment_n may_v escape_v his_o notice_n and_o consequent_o want_v his_o assistance_n by_o way_n of_o defence_n for_o it_o be_v manifest_a that_o when_o his_o attention_n be_v divert_v by_o any_o object_n more_o especial_o by_o such_o as_o mighty_o please_v he_o as_o in_o the_o act_n of_o venery_n and_o other_o pleasure_n especial_o if_o intense_a that_o he_o do_v not_o perceive_v other_o object_n at_o the_o time_n that_o he_o be_v so_o divert_v and_o if_o the_o pleasant_a diversion_n be_v intense_a and_o permanent_a as_o in_o the_o case_n of_o opium_n and_o wine_n drink_v in_o a_o considerable_a quantity_n he_o be_v so_o take_v up_o divert_v or_o charm_v therewith_o that_o he_o do_v not_o attend_v to_o the_o business_n of_o sensation_n this_o be_v one_o reason_n why_o such_o as_o be_v far_o go_v in_o drink_n have_v none_o of_o their_o sense_n aright_o but_o as_o to_o the_o illustration_n of_o this_o matter_n you_o may_v expect_v more_o hereafter_o note_v that_o the_o sensitive_a soul_n be_v the_o only_a thing_n iâ—_n a_o animal_n that_o have_v perception_n and_o therefore_o the_o only_a thing_n that_o be_v sensible_a of_o any_o grievance_n weariness_n hunger_n pleasure_n comfort_n etc._n etc._n second_o it_o be_v requisite_a that_o it_o shall_v use_v all_o mean_n that_o be_v in_o its_o power_n that_o the_o impression_n shall_v be_v bring_v to_o it_o very_o entire_o exact_o smart_o etc._n etc._n so_o as_o to_o have_v due_a notice_n of_o all_o object_n and_o the_o small_a impression_n that_o may_v be_v for_o which_o good_a end_n and_o purpose_v god_n have_v endue_v the_o sensitive_a soul_n as_o will_v be_v full_o prove_v with_o a_o power_n of_o contract_v all_o the_o sensile_n small_a and_o slender_a pipe_n vessel_n or_o passage_n of_o the_o animal_n spirit_n for_o the_o more_o express_a distinct_a and_o accurate_a conveyance_n of_o all_o impression_n by_o the_o help_n of_o compression_n therefore_o the_o sensitive_a soul_n take_v the_o advantage_n thereof_o for_o better_a information_n in_o order_n to_o self-preservation_n do_v by_o the_o appointment_n of_o the_o preserver_n of_o all_o thing_n execute_v his_o power_n by_o the_o aforementioned_a vigilative_a contraction_n of_o those_o part_n to_o cause_v their_o tension_n and_o great_a compression_n of_o the_o animal_n spirit_n to_o improve_v the_o impression_n that_o be_v to_o be_v convey_v to_o he_o and_o render_v they_o more_o observable_a this_o god_n who_o have_v make_v nothing_o to_o be_v idle_a and_o particular_o order_v the_o sensitive_a soul_n in_o adam_n for_o labour_n especeal_o in_o reference_n to_o their_o own_o safety_n and_o preservation_n have_v make_v to_o be_v the_o ordinary_a employ_v or_o day-work_a of_o the_o sensitive_a soul_n that_o by_o the_o say_v vigilative_a contraction_n the_o organ_n membrane_n vessel_n etc._n etc._n may_v be_v render_v more_o tense_n and_o firm_a and_o the_o animal_n spirit_n more_o compress_v springy_a prompt_a flippant_a and_o forcible_a for_o the_o benefit_n of_o sense_n and_o motion_n upon_o all_o occasion_n of_o defence_n flight_n struggle_v etc._n etc._n which_o be_v our_o state_n of_o vigilancy_n as_o have_v be_v intimate_v but_o the_o keep_n of_o the_o say_a part_n membrane_n etc._n etc._n in_o continual_a contraction_n even_o against_o the_o renitency_n of_o the_o elastic_a spirit_n which_o resist_v and_o thrust_v the_o hard_a against_o their_o vessel_n by_o how_o much_o the_o more_o they_o compress_v they_o by_o the_o vigilative_a contraction_n be_v a_o continual_a tedious_a labour_n and_o fatigue_n of_o which_o the_o sensitive_a soul_n be_v sensible_a as_o the_o only_a perceiver_n of_o lassitude_n or_o indeed_o of_o any_o thing_n beside_o in_o a_o animal_n and_o in_o his_o nature_n but_o material_a changeable_a fatigable_a frail_a subject_a to_o be_v wear_v out_o and_o capable_a of_o decay_n which_o make_v the_o certainty_n of_o death_n in_o all_o animal_n and_o in_o we_o since_o the_o fall_n into_o a_o animal_n nature_n do_v upon_o that_o account_n and_o lest_o the_o continual_a contraction_n and_o tensive_a stress_n of_o part_n by_o that_o mean_n shall_v spoil_v their_o tone_n and_o to_o recruit_v the_o waste_a spirit_n by_o rest_n after_o tuggingall_a day_n at_o the_o vigilative_a contraction_n grow_v willing_a to_o give_v over_o the_o drudgery_n however_o convenient_a for_o the_o use_v aforesaid_a therefore_o be_v allow_v convenient_a rest_n by_o his_o maker_n he_o for_o the_o great_a benefit_n of_o refection_n without_o which_o he_o can_v continue_v his_o be_v and_o for_o the_o sweetness_n of_o ease_n loosen_v the_o reins_o of_o vigilative_a contraction_n whereupon_o sensation_n and_o promptitude_n to_o motion_n which_o be_v maintain_v by_o that_o contraction_n cause_v the_o tension_n of_o organ_n and_o compression_n of_o the_o animal_n spirit_n as_o have_v be_v mechanical_o demonstrate_v fail_v by_o the_o relaxation_n of_o those_o organ_n membrane_n and_o vessel_n of_o the_o spirit_n and_o the_o consequent_a expansion_n of_o the_o animal_n spirit_n so_o that_o now_o only_a the_o compression_n of_o the_o atmosphere_n remain_v which_o as_o you_o see_v in_o a_o gut_n half_n full_a of_o air_n under_o that_o pressure_n be_v not_o sufficient_a to_o convey_v the_o impression_n with_o any_o smartness_n or_o cause_v the_o animal_n spirit_n to_o spring_v vigorous_o into_o motion_n which_o decay_n or_o failure_n of_o sense_n and_o motion_n by_o relaxation_n and_o the_o consequent_a expansion_n of_o the_o animal_n spirit_n be_v the_o state_n of_o natural_a sleep_n note_v that_o relaxation_n be_v a_o necessary_a consequence_n of_o the_o privation_n of_o contraction_n and_o require_v no_o labour_n but_o a_o bare_a remission_n of_o that_o contraction_n note_v that_o the_o watch_a part_n of_o our_o life_n be_v uphold_v by_o force_n and_o that_o nullum_fw-la violentum_fw-la est_fw-la diuturnum_fw-la and_o consequent_o a_o necessity_n of_o sleep_n and_o at_o last_o of_o death_n itself_o thus_o have_v you_o the_o true_a reason_n of_o sleep_v and_o watch_v which_o will_v natural_o plain_o and_o easy_o solve_v all_o the_o phenomena_n thereof_o for_o it_o be_v most_o evident_a from_o the_o premise_n 1._o why_o watch_v and_o sleep_v observe_v a_o proportion_n between_o they_o the_o be_v tire_v with_o one_o be_v the_o cause_n of_o the_o other_o 2._o why_o sense_n and_o motion_n do_v fail_v so_o much_o in_o sleep_n viz._n by_o the_o relaxation_n of_o all_o part_n and_o expansion_n of_o the_o animal_n spirit_n 3._o why_o they_o always_o fail_v together_o and_o in_o like_a proportion_n 4._o why_o they_o do_v not_o whole_o fail_v in_o sleep_n because_o the_o compressure_n of_o the_o atmosphere_n etc._n etc._n remain_v 5._o why_o in_o sleep_v the_o limb_n be_v like_o a_o gut_n half_n full_a of_o air_n lax_n limber_a flaccid_a and_o yield_v all_o manner_n of_o way_n because_o all_o the_o innumerable_a small_a vessel_n that_o contain_v the_o elastic_a animal_n spirit_n be_v as_o that_o half_a fill_v gut_n i_o mention_v not_o tight_o fill_v which_o if_o they_o be_v will_v be_v firm_a and_o tense_n as_o such_o a_o gut_n blow_v up_o very_o full_a and_o forcible_o be_v which_o vessel_n be_v all_o over_o the_o body_n confirm_v the_o whole_a tone_n when_o we_o be_v awake_a and_o the_o vigilative_a contraction_n compress_n the_o animal_n spirit_n into_o a_o steadiness_n and_o as_o it_o be_v a_o kind_a of_o solidity_n 6._o why_o as_o appear_v by_o statick_a demonstration_n and_o experiment_n we_o perspire_v more_o when_o asleep_a than_o awake_a because_o the_o pore_n be_v close_v by_o the_o vigilative_a contraction_n and_o open_v in_o sleep_n by_o the_o contrary_a relaxation_n which_o therefore_o always_o cause_v free_a perspiration_n where_o ever_o it_o happen_v as_o in_o faint_a fit_n syncopes_fw-la leipothymy_n and_o by_o warmth_n especial_o if_o moist_a and_o emollient_a as_o in_o bath_n fomentation_n foot_n wash_v head_n wash_v etc._n etc._n as_o also_o when_o pleasure_n relax_n as_o in_o the_o act_n of_o venery_n great_a joy_n after_o good_a meal_n or_o some_o glass_n of_o wine_n etc._n etc._n all_o which_o cause_n plentiful_a perspiration_n because_o they_o relax_v and_o thereby_o open_a the_o pore_n as_o more_o full_o appear_v in_o the_o follow_a discourse_n by_o reason_n of_o the_o pleasure_n that_o they_o cause_n which_o divert_v the_o sensitive_a soul_n from_o his_o employ_v of_o contraction_n 7._o why_o the_o pore_n be_v open_a by_o the_o relaxation_n we_o sweat_v in_o our_o sleep_n if_o we_o be_v fill_v with_o matter_n for_o it_o viz._n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o be_v much_o sweat_v in_o sleep_n argue_v that_o much_o food_n or_o nutriment_n be_v take_v of_o which_o drink_n be_v the_o great_a part_n in_o bulk_n even_o in_o sober_a person_n i_o mention_v this_o to_o show_v the_o difference_n in_o the_o case_n of_o perspiration_n and_o sweat_v for_o that_o always_o happen_v in_o sleep_n but_o not_o sweat_v unless_o
the_o body_n be_v well_o fill_v with_o moisture_n to_o show_v the_o cause_n of_o which_o difference_n will_v be_v the_o business_n of_o my_o tract_n of_o animal_n mechanism_n if_o i_o have_v not_o hereafter_o a_o occasion_n to_o do_v it_o in_o this_o tract_n as_o i_o suppose_v i_o may_v 8._o why_o sleep_n cure_v cold_n by_o open_v the_o pore_n 9_o why_o the_o skin_n be_v more_o florid_n in_o sleep_n because_o as_o have_v be_v say_v it_o be_v relax_v admit_v the_o blood_n into_o it_o which_o vigilative_a contraction_n do_v in_o good_a measure_n repel_v and_o thereby_o cause_v the_o skin_n to_o appear_v more_o white_a and_o pale_a as_o it_o be_v and_o any_o one_o may_v observe_v upon_o awake_v 10._o why_o the_o eye_n look_v deadish_a in_o sleep_n viz._n because_o as_o have_v be_v show_v the_o humour_n do_v not_o fill_v up_o the_o relax_v cornea_n to_o a_o due_a tension_n and_o rotundity_n which_o as_o be_v say_v make_v the_o cornea_n shine_v sparkle_v and_o particular_o to_o reflect_v a_o brisk_a speck_n of_o light_n as_o shine_v round_a thing_n must_v do_v which_o speck_n if_o painter_n omit_v the_o eye_n look_v deadish_a therefore_o they_o shall_v when_o they_o have_v a_o mind_n to_o express_v the_o deadness_n of_o the_o eye_n as_o in_o faint_v fit_n syncopes_fw-la sleep_n death_n wanton_a loose_a ogling_n of_o lover_n drunkenness_n etc._n etc._n omit_v that_o speck_n or_o rather_o draw_v it_o dull_a wide_a and_o discompose_v in_o figure_n with_o the_o pupil_n very_o large_a and_o the_o upper_a eyelid_n fall_v down_o loose_o which_o will_v exact_o express_v the_o deadness_n of_o the_o eye_n in_o all_o those_o case_n of_o relaxation_n in_o which_o alone_o it_o so_o appear_v note_v that_o the_o reason_n why_o some_o in_o such_o case_n see_v divers_a colour_n before_o their_o eye_n be_v because_o the_o uneven_a cornea_n various_o retract_v and_o reflect_v the_o light_n which_o i_o mention_v because_o none_o that_o i_o know_v of_o have_v observe_v the_o cause_n 11._o why_o people_n be_v more_o sleepy_a in_o warm_a moist_a wether_n viz._n because_o the_o part_n be_v more_o relax_v and_o the_o pressure_n of_o the_o atmosphere_n less_o to_o assist_v the_o vigilative_a contraction_n to_o keep_v we_o in_o a_o wake_a state_n by_o the_o compressure_n of_o the_o animal_n spirit_n how_o much_o better_a therefore_o be_v a_o cool_a and_o dry_a air_n that_o raise_v the_o mercury_n high_a in_o the_o barometer_n or_o wether_n glass_n both_o for_o heath_n and_o action_n because_o it_o render_v the_o animal_n spirit_n more_o powerful_a prompt_a and_o flippant_a by_o the_o compression_n this_o shall_v be_v observe_v by_o such_o as_o be_v to_o run_v race_n alone_o lift_v weight_n or_o perform_v any_o thing_n that_o require_v strength_n vigour_n or_o speed_v nor_o can_v i_o doubt_v but_o if_o we_o have_v a_o artificial_a mean_n to_o compress_v man_n body_n in_o a_o high_a manner_n as_o by_o put_v they_o into_o convenient_a cavity_n and_o force_v air_n upon_o they_o but_o they_o will_v be_v much_o strong_a for_o the_o time_n and_o thereby_o enable_v to_o do_v exploit_n beyond_o their_o ordinary_a strength_n which_o put_v i_o in_o mind_n of_o several_a thing_n that_o confirm_v it_o very_o much_o as_o man_n lift_v of_o great_a weight_n in_o low_a place_n than_o on_o the_o top_n of_o very_o high_a hill_n where_o the_o pressure_n of_o the_o air_n be_v less_o to_o compress_v the_o animal_n spirit_n the_o contraction_n of_o all_o part_n in_o lift_v of_o great_a weight_n the_o prodigious_a leap_v and_o swiftness_n of_o some_o person_n in_o great_a fright_v terror_n etc._n etc._n which_o mighty_o contract_v the_o sensile_a part_n and_o vessel_n of_o the_o animal_n spirit_n by_o which_o mean_v they_o be_v render_v more_o springy_a and_o powerful_a note_v that_o the_o true_a cause_n of_o strength_n be_v the_o compression_n of_o the_o animal_n spirit_n and_o that_o probable_o the_o force_n of_o muscle_n may_v some_o way_n or_o other_o depend_v upon_o it_o which_o be_v not_o my_o business_n to_o explain_v at_o present_a note_v that_o it_o be_v the_o membrane_n be_v primary_o contract_v and_o the_o medullary_a part_n of_o the_o nerve_n spirit_n etc._n etc._n compress_a thereby_o by_o consequence_n 12._o why_o the_o soft_a flesh_v and_o moist_a be_v more_o sleepy_a as_o child_n etc._n etc._n viz._n because_o the_o compression_n of_o their_o animal_n spirit_n be_v not_o so_o great_a by_o reason_n of_o the_o laxity_n of_o their_o part_n so_o be_v they_o weak_a for_o the_o same_o reason_n which_o tell_v you_o why_o little_a man_n who_o flesh_n be_v firm_a that_o be_v no_o big_a than_o boy_n be_v much_o strong_a than_o boy_n or_o woman_n of_o the_o same_o bigness_n 13._o why_o warm_a and_o emollient_a bath_n fomentation_n foot_n or_o head_n wash_v etc._n etc._n do_v as_o moist_a and_o warm_a wether_n cause_n sleepiness_n and_o indeed_o all_o thing_n that_o cause_n relaxation_n or_o incline_v the_o sensitive_a soul_n to_o leave_v off_o contract_n as_o weariness_n etc._n etc._n do_v cause_n sleep_v note_v that_o in_o dry_a body_n as_o old_a people_n etc._n etc._n such_o emollient_a bath_n fomentation_n etc._n etc._n with_o the_o use_n of_o emollient_a moistner_n inward_o will_v cause_v sleep_n very_o fine_o when_o opium_n itself_o will_v not_o and_o that_o opium_n in_o such_o case_n shall_v be_v use_v with_o such_o thing_n both_o internal_o and_o external_o but_o which_o be_v not_o observe_v the_o bath_n fomentation_n etc._n etc._n shall_v not_o be_v above_o the_o warmth_n of_o blood_n because_o the_o heat_n may_v otherwise_o cause_v too_o much_o motion_n of_o the_o blood_n and_o spirit_n which_o be_v a_o great_a enemy_n to_o sleep_n that_o consist_v in_o their_o rest_n and_o the_o aforesaid_a relaxation_n of_o part_n by_o both_o which_o cooperate_a you_o may_v and_o can_v fail_v to_o cause_v any_o man_n to_o sleep_n if_o you_o can_v make_v they_o concur_v 14._o the_o same_o relaxation_n cause_v the_o pulse_n to_o be_v large_a and_o slow_a in_o sleep_n nocturnal_a pollution_n want_v of_o due_a contraction_n and_o sensation_n at_o stomach_n by_o which_o mean_v the_o meat_n stay_v long_a there_o in_o our_o sleep_n than_o when_o we_o be_v awake_a so_o 15._o fret_n commotion_n and_o perturbation_n of_o the_o spirit_n etc._n etc._n be_v compose_v by_o sleep_n because_o the_o sensitive_a soul_n who_o be_v the_o original_a of_o all_o motion_n be_v at_o rest_n and_o that_o the_o animal_n spirit_n be_v expanded_a be_v near_o their_o absolute_a rest_n which_o consist_v in_o a_o full_a and_o perfect_a expansion_n so_o that_o there_o be_v no_o far_a endeavour_n towards_o motion_n 16._o sensation_n be_v much_o lessen_v by_o the_o expansion_n of_o the_o animal_n spirit_n upon_o the_o say_a relaxation_n the_o sense_n of_o the_o irritation_n of_o humour_n be_v thereby_o lessen_v or_o quite_o take_v away_o whereupon_o all_o flux_n occasion_v by_o the_o irritation_n of_o humour_n as_o diarrhea_n disentery_n catarrh_n etc._n etc._n be_v stop_v or_o moderate_v at_o least_o by_o sleep_n beside_o that_o relaxation_n be_v quite_o contrary_a to_o contraction_n by_o which_o those_o humour_n be_v squeeze_a out_o let_v we_o the_o humour_n stay_v quiet_o where_o they_o be_v relaxation_n be_v more_o for_o receive_v contain_v detain_v and_o suspending_a humour_n in_o the_o part_n than_o send_v they_o forward_o as_o you_o see_v in_o a_o sponge_n first_o contract_v and_o afterward_o suffer_v to_o dilate_v or_o expand_v itself_o in_o a_o dish_n that_o have_v some_o water_n in_o it_o which_o it_o take_v into_o itself_o and_o suspend_v till_o something_o squeese_v it_o out_o by_o contract_v it_o 17._o therefore_o it_o be_v that_o the_o spital_n do_v not_o come_v into_o the_o mouth_n in_o sleep_n or_o very_o little_a and_o that_o people_n be_v apt_a to_o awake_v thirsty_a though_o it_o be_v soon_o take_v off_o in_o some_o measure_n by_o the_o vigilative_a contraction_n squeeze_v out_o the_o spital_n into_o the_o mouth_n unless_o there_o be_v some_o special_a cause_n to_o the_o contrary_n 18._o for_o the_o same_o reason_n the_o menstruum_fw-la of_o the_o stomach_n come_v but_o very_o slow_o into_o the_o stomach_n in_o sleep_n which_o be_v one_o cause_v that_o digestion_n go_v on_o but_o slow_o in_o sleep_n note_v that_o digestion_n and_o send_v the_o chyle_n out_o of_o the_o stomach_n depend_v both_o upon_o contraction_n they_o be_v hasten_v and_o retard_v in_o exact_a proportion_n so_o that_o the_o extrusion_n keep_v equal_a pace_n with_o the_o digestion_n how_o equal_a and_o due_o proportion_v be_v the_o work_n of_o nature_n 19_o it_o be_v plain_a also_o from_o what_o have_v be_v state_v concern_v sleep_n why_o ague_n fit_v seldom_o if_o ever_o take_v people_n in_o the_o time_n of_o their_o first_o sound_n sleep_v because_o the_o shiver_a be_v cause_v by_o a_o grievous_a
by_o squeeze_v in_o some_o case_n and_o stop_v it_o by_o shut_v the_o pore_n in_o other_o case_n 10._o it_o be_v by_o it_o that_o contraction_n that_o fear_v cold_a etc._n etc._n close_v the_o pore_n and_o repel_v the_o blood_n staunch_a bleed_a so_o happen_v also_o a_o great_a contraction_n of_o the_o pupil_n of_o the_o eye_n by_o the_o same_o cause_n 11._o it_o be_v the_o violence_n of_o this_o contraction_n upon_o fear_n terror_n pain_n cold_a etc._n etc._n close_v the_o small_a vessel_n of_o the_o animal_n spirit_n and_o thereby_o repel_v they_o cause_v the_o shiver_a in_o those_o case_n by_o the_o renitency_n of_o the_o elastic_a animal_n spirit_n spring_v back_o again_o toties_fw-la quoties_fw-la have_v gain_v more_o elastic_a force_n by_o the_o very_a compression_n itself_o which_o that_o contraction_n cause_n so_o that_o by_o reason_n of_o the_o dubious_a velitation_n or_o skirmish_v between_o the_o repel_v contraction_n and_o the_o spring_a spirit_n happen_v a_o tremulous_a motion_n as_o of_o quaver_v spring_n which_o shiver_a in_o ague-fits_a do_v former_o lead_v i_o to_o the_o situation_n of_o the_o cause_n of_o ague_n when_o i_o write_v my_o book_n de_fw-fr febribus_fw-la intermittentibus_fw-la in_o the_o angustiae_fw-la at_o the_o end_n of_o the_o vessel_n which_o terminate_v in_o the_o membrane_n the_o grievous_a sensation_n of_o which_o cause_v all_o the_o shiver_a that_o happen_v in_o any_o case_n to_o animal_n 12._o by_o the_o same_o contraction_n when_o very_o violent_a and_o of_o the_o whole_a body_n cold_a sweat_v happen_v in_o pain_n fear_v terror_n etc._n etc._n while_o it_o violent_o squeeze_v out_o the_o outmost_a and_o therefore_o cold_a moisture_n of_o our_o body_n as_o laundress_n do_v water_n out_o of_o wet_a linen_n by_o contortion_n thus_o if_o you_o dip_v one_o half_a of_o a_o wet_a cold_a sheet_n in_o hot_a water_n wrap_v the_o hot_a side_n within_o the_o cold_a or_o let_v a_o warm_a sheet_n that_o be_v contort_a cool_a on_o the_o outside_n of_o it_o and_o then_o wring_v it_o as_o woman_n do_v linen_n the_o water_n that_o first_o exudate_n will_v be_v cold_a for_o in_o this_o case_n the_o close_n of_o the_o pore_n avail_v nothing_o to_o hinder_v it_o as_o long_o as_o the_o express_a force_n master_n it_o more_o especial_o in_o animal_n body_n wherein_o the_o part_n be_v so_o contrive_v that_o humour_n design_v for_o exoretion_n can_v well_o return_v and_o therefore_o must_v upon_o contraction_n run_v out_o hence_o it_o be_v that_o alum_n or_o vitriol_n which_o be_v very_o astringent_a and_o therefore_o close_a the_o pore_n will_v notwithstanding_o cause_v the_o mouth_n or_o nose_n to_o run_v very_o plentiful_o with_o moisture_n by_o contract_v all_o the_o membrane_n about_o the_o mouth_n or_o nose_n and_o thereby_o squeeze_v out_o the_o moisture_n design_v to_o be_v excern_v which_o can_v return_v because_o the_o part_n be_v contrive_v against_o the_o return_n or_o readmittance_n thereof_o whereas_o alum_n or_o vitriol_n will_v staunch_v or_o stop_v blood_n by_o the_o same_o contraction_n because_o it_o may_v return_v as_o not_o be_v design_v to_o be_v excern_v either_o into_o the_o artery_n and_o so_o pass_v by_o other_o branch_n thereof_o or_o which_o be_v more_o ready_a and_o natural_a keep_v its_o course_n into_o the_o vein_n so_o the_o two_o riddle_n that_o i_o have_v know_v some_o proud_a physician_n amaze_v at_o though_o but_o trifle_n of_o alum_n and_o vitriol_n cause_v the_o spital_n etc._n etc._n to_o come_v out_o instead_o of_o stop_v it_o by_o their_o astringency_n and_o their_o stop_a blood_n at_o nose_n at_o the_o same_o time_n they_o cause_v the_o snot_n or_o other_o humour_n to_o run_v out_o be_v unfold_v 13._o it_o be_v by_o this_o mighty_a contraction_n grow_v to_o a_o enormous_a degree_n that_o the_o animal_n spirit_n be_v violent_o compress_v grow_v exceed_o irrequiete_a as_o upon_o convulsion_n in_o great_a pain_n or_o very_o grievous_a sensation_n at_o stomach_n etc._n etc._n while_o the_o sensitive_a soul_n compress_v they_o with_o mighty_a force_n and_o somewhat_o disorderly_a and_o uneven_o because_o of_o the_o confusion_n and_o hurry_n he_o be_v in_o to_o relieve_v the_o animal_n they_o by_o their_o springiness_n fling_v up_o and_o down_o with_o great_a vigour_n this_o make_v convulsive_a motion_n have_v great_a strength_n 14._o the_o body_n under_o this_o contraction_n be_v manifest_o shrink_v by_o measure_n especial_o when_o the_o sensation_n be_v very_o grievous_a but_o most_o of_o all_o if_o they_o cause_v a_o general_a convulsion_n which_o i_o manifest_o observe_v in_o a_o little_a bitch_n that_o be_v convulsive_a all_o over_o for_o three_o hour_n and_o be_v just_a expire_n when_o i_o give_v she_o the_o sal_fw-la volat._n oleo_n of_o opium_n which_o perfect_o restore_v she_o by_o relax_v the_o vessel_n some_o may_v think_v it_o strange_a that_o nature_n shall_v contrive_v a_o more_o nice_a and_o smart_a sensation_n which_o the_o contraction_n of_o the_o vessel_n of_o the_o animal_n spirit_n must_v cause_v by_o compress_v they_o etc._n etc._n in_o pain_n and_o by_o it_o which_o become_v so_o much_o the_o more_o acute_a whereas_o one_o will_v judge_v that_o nature_n will_v rather_o contrive_v its_o ease_n than_o improve_v its_o smart_n you_o be_v to_o know_v that_o the_o pain_n be_v in_o order_n to_o relieve_v the_o animal_n by_o exciting_a all_o its_o power_n to_o defend_v expel_v or_o reject_v the_o cause_n and_o that_o without_o a_o grievous_a sensation_n the_o sensitive_a soul_n be_v neither_o mind_v nor_o excite_v to_o do_v it_o and_o the_o more_o the_o pain_n be_v the_o more_o it_o be_v stir_v up_o to_o self-preservation_n and_o as_o be_v show_v the_o more_o vigorous_a do_v its_o motion_n grow_v by_o the_o compression_n of_o the_o elastic_a spirit_n to_o perform_v that_o work_n so_o nature_n not_o regard_v the_o pain_n which_o be_v rather_o for_o good_a as_o much_o as_o take_v away_o the_o cause_n advance_v that_o for_o this_o purpose_n like_o a_o wise_a physician_n who_o find_v a_o grievance_n at_o stomach_n not_o sufficient_a to_o excite_v effectual_a vomit_v to_o throw_v away_o the_o grieve_v cause_n add_v to_o the_o grievance_n by_o give_v a_o vomit_n which_o because_o as_o be_v say_v nature_n be_v proportionable_o excite_v to_o and_o invigorate_v for_o self-preservation_n sufficient_o solicit_v and_o enable_v it_o by_o a_o strong_a contraction_n to_o reject_v the_o grieve_v matter_n as_o the_o great_a the_o relaxation_n be_v the_o more_o be_v the_o rest_n of_o all_o part_n and_o the_o weak_a the_o animal_n spirit_n because_o less_o compress_v the_o gentle_a be_v all_o motion_n as_o you_o see_v in_o sleep_n consequent_o the_o less_o be_v the_o expense_n of_o spirit_n so_o that_o in_o sleep_n we_o generate_v more_o than_o we_o spend_v and_o be_v thereby_o recruit_v so_o the_o more_o the_o contraction_n be_v the_o more_o violent_a be_v the_o motion_n of_o the_o heart_n intestine_n and_o of_o all_o part_n and_o consequent_o the_o expense_n of_o spirit_n be_v the_o great_a therefore_o it_o can_v be_v no_o wonder_n that_o contraction_n do_v cause_n great_a commotion_n of_o spirit_n diary_n fever_n etc._n etc._n when_o you_o consider_v 1._o that_o the_o sensitive_a soul_n be_v by_o the_o grievous_a sensation_n etc._n etc._n that_o cause_n they_o put_v upon_o a_o great_a fret_v concern_v and_o hurry_v to_o defend_v the_o animal_n and_o lay_v about_o he_o all_o manner_n of_o way_n for_o self-preservation_n 2._o that_o the_o animal_n spirit_n be_v by_o mean_n of_o great_a compression_n cause_v by_o the_o defensive_a contraction_n in_o a_o very_a forcible_a springiness_n which_o cause_v all_o the_o action_n that_o be_v continual_a involuntary_a and_o of_o course_n to_o be_v perform_v with_o great_a violence_n proportionable_a to_o its_o compress_a elasticity_n beside_o that_o 3._o the_o systole_n of_o the_o heart_n be_v oftener_o repeat_v all_o which_o conspire_v to_o cause_v great_a commotion_n upon_o grievous_a sensation_n whereby_o diary_n fever_n etc._n etc._n be_v cause_v which_o be_v easy_o and_o natural_o cure_v by_o sleep_n or_o relaxation_n at_o present_a compose_v and_o quiet_v those_o perturbation_n who_o know_v though_o it_o be_v not_o my_o business_n to_o discuss_v it_o at_o present_a but_o that_o the_o contraction_n in_o the_o cold_a fit_n of_o ague_n have_v a_o great_a hand_n in_o cause_v the_o hot_a one_o how_o otherwise_o shall_v opium_n by_o only_o take_v away_o the_o grievous_a sensation_n of_o the_o cold_a fit_n take_v off_o or_o prevent_v the_o hot_a fit_n also_o but_o of_o this_o in_o my_o often-mentioned_n tract_n though_o not_o so_o often_o as_o it_o grieve_v i_o that_o it_o be_v not_o publish_v how_o reasonable_o may_v we_o now_o expect_v that_o pleasant_a sensation_n may_v cause_v quite_o contrary_a effect_n to_o that_o of_o grievous_a sensation_n viz._n relaxation_n and_o all_o its_o effect_n
be_v well_o remove_v this_o prove_v how_o useful_a removal_n may_v be_v and_o how_o convenient_a in_o plague_n time_n it_o will_v be_v to_o remove_v to_o the_o wind-side_n of_o a_o town_n or_o city_n that_o be_v taint_v according_a as_o the_o wind_n change_v and_o how_o convenient_a wind_n be_v to_o convey_v away_o the_o effluviams_n and_o good_a stomachick_a cordial_n that_o be_v warm_a and_o pleasant_a to_o fortify_v the_o stomach_n and_o open_v the_o pore_n which_o all_o thing_n that_o cause_v a_o sense_n of_o pleasure_n do_v as_o wine_n spirit_n etc._n etc._n to_o which_o if_o some_o good_a preparation_n of_o opium_n be_v add_v it_o will_v be_v most_o convenient_a how_o many_o story_n have_v we_o of_o person_n well_o fill_v with_o wine_n who_o wonderful_o escape_v infection_n i_o pray_v god_n this_o hint_n may_v be_v improve_v to_o the_o preservation_n of_o mankind_n therefore_o i_o add_v that_o much_o may_v be_v in_o a_o good_a quantity_n of_o wine_n in_o this_o case_n 1._o because_o quod_fw-la intus_fw-la est_fw-la prohibet_fw-la alienum_fw-la that_o be_v what_o be_v within_o hinder_v ingress_n of_o another_o thing_n 2._o because_o the_o perspiration_n will_v be_v the_o great_a both_o upon_o the_o account_n of_o the_o great_a open_n of_o the_o pore_n by_o the_o pleasure_n of_o the_o wine_n and_o the_o great_a quantity_n of_o matter_n to_o be_v perspire_v carry_v off_o the_o venomous_a particle_n 3._o because_o the_o sensitive_a soul_n be_v thereby_o much_o comfort_v refresh_v and_o invigorate_v but_o i_o will_v have_v the_o wine_n so_o use_v as_o to_o keep_v a_o continual_a warmth_n pleasure_n and_o comfort_n at_o stomach_n which_o be_v the_o main_a cause_n of_o all_o the_o good_a i_o think_v a_o glass_n every_o hour_n after_o take_v 2_o or_o 3_o at_o first_o may_v hit_v the_o mark_n best_o the_o reason_n of_o which_o will_v appear_v hereafter_o three_o the_o stomach_n be_v exquisite_a disposition_n to_o sensation_n above_o all_o other_o organ_n and_o membrane_n appear_v by_o this_o viz._n that_o the_o offence_n of_o the_o other_o organ_n of_o sensation_n even_o by_o their_o proper_a object_n do_v often_o affect_v the_o stomach_n more_o than_o those_o very_a sense_n or_o organ_n themselves_o for_o instance_n if_o we_o smell_v a_o great_a stench_n the_o stomach_n be_v often_o more_o offend_v thereat_o than_o the_o nose_n as_o be_v manifest_a from_o the_o vomit_n faint_n and_o deliquium_n that_o be_v cause_v by_o the_o stomach_n upon_o that_o account_n so_o the_o bare_a see_v feel_v and_o taste_v of_o a_o nasty_a thing_n do_v cause_n nauseas_fw-la etc._n etc._n at_o stomach_n yea_o the_o very_a name_n of_o such_o thing_n have_v much_o offend_v it_o and_o cause_v such_o effect_n which_o may_v be_v think_v very_o strange_a consider_v that_o there_o pass_v no_o effluvias_fw-la from_o the_o sound_n of_o word_n but_o the_o reason_n will_v appear_v in_o the_o follow_a paragraph_n four_o all_o passion_n commotion_n and_o perturbation_n that_o happen_v in_o the_o body_n do_v often_o affect_v the_o stomach_n and_o sometime_o so_o grievous_o as_o to_o cause_n nauseas_fw-la vomit_n great_a anxiety_n at_o stomach_n faint_n etc._n etc._n thus_o fear_v terror_n surprise_v anger_n grief_n pain_n in_o other_o part_n etc._n etc._n cause_v some_o motion_n in_o the_o animal_n more_o than_o ordinary_a of_o which_o the_o stomach_n be_v sensible_a do_v cause_n the_o aforesaid_a disturbance_n therefore_o it_o be_v no_o wonder_n if_o the_o hear_v one_o mention_n a_o nasty_a thing_n which_o cause_v a_o abhorrence_n and_o the_o motion_n consequent_a thereunto_o shall_v as_o be_v say_v in_o the_o precedent_n paragraph_n cause_v the_o nice_a stomach_n to_o be_v offend_v it_o be_v most_o manifest_a from_o the_o premise_n that_o no_o organ_n or_o membrane_n can_v compare_v with_o the_o stomach_n as_o to_o its_o exquisite_a disposition_n for_o sensation_n it_o follow_v then_o that_o grievance_n or_o pleasure_n at_o stomach_n must_v have_v the_o great_a effect_n 1._o because_o the_o intenseness_n of_o either_o will_v be_v proportionable_a to_o the_o sensation_n 2._o because_o the_o power_n of_o the_o animal_n that_o be_v to_o defend_v it_o which_o be_v contraction_n be_v affect_v according_a to_o the_o sensation_n and_o that_o it_o be_v there_o most_o requisite_a sensible_o to_o affect_v they_o 3._o because_o what_o affect_v the_o stomach_n influence_n the_o whole_a animal_n more_o than_o the_o sensation_n of_o any_o other_o part._n 4._o because_o of_o the_o considerable_a stay_v that_o thing_n make_v at_o stomach_n to_o cause_n grievance_n or_o pleasure_n whereas_o that_o of_o pleasure_n be_v general_o very_o momentary_a in_o other_o case_n 5._o because_o be_v within_o the_o body_n we_o carry_v our_o pleasure_n or_o grievance_n with_o we_o as_o a_o vade_fw-la mecum_fw-la wherever_o we_o go_v and_o therefore_o 6._o it_o be_v a_o pleasure_n etc._n etc._n that_o can_v so_o well_o be_v take_v away_o from_o we_o as_o that_o of_o the_o tongue_n ear_n nose_n eye_n etc._n etc._n may_v by_o remove_v the_o object_n and_o therefore_o it_o remain_v with_o we_o in_o our_o very_a sleep_n as_o far_o as_o we_o be_v capable_a of_o sensation_n at_o that_o time_n cause_v pleasant_a dream_n etc._n etc._n and_o so_o agreeable_o entertain_v we_o sleep_v or_o wake_v when_o the_o pleasure_n of_o all_o the_o other_o sense_n fail_v we_o which_o will_v appear_v far_o hereafter_o the_o pleasure_n at_o stomach_n excel_v even_o that_o of_o venery_n if_o not_o in_o intenseness_n yet_o in_o several_a other_o respect_n viz._n 1._o because_o of_o its_o duration_n that_o of_o venus_n be_v momentary_a but_o that_o of_o wine_n at_o stomach_n last_v a_o good_a while_n and_o that_o of_o opium_n many_o hour_n it_o be_v therefore_o that_o the_o effect_n of_o these_o two_o be_v more_o remarkable_a and_o take_v notice_n of_o 2._o because_o that_o at_o stomach_n may_v be_v continue_v as_o long_o as_o we_o please_v by_o a_o new_a supply_n of_o wine_n opium_n cordial_n etc._n etc._n 3._o because_o it_o may_v be_v excite_v when_o and_o as_o often_o as_o we_o please_v if_o we_o have_v those_o cordial_n at_o hand_n 4._o because_o it_o be_v not_o attend_v with_o any_o expense_n of_o strength_n depression_n of_o spirit_n etc._n etc._n as_o that_o of_o venery_n but_o the_o quite_o contrary_a viz._n with_o more_o vigour_n elevation_n of_o the_o spirit_n etc._n etc._n one_o be_v by_o emission_n and_o the_o other_o upon_o admission_n of_o what_o be_v agreeable_a it_o be_v for_o the_o several_a reason_n contain_v in_o the_o premise_n that_o the_o effect_n of_o grievance_n as_o hunger_n etc._n etc._n or_o pleasure_n be_v more_o considerable_a and_o remarkable_a at_o stomach_n and_o that_o thing_n agreeable_a thereto_o have_v by_o way_n of_o eminence_n gain_v the_o name_n of_o cordial_n that_o wine_n spirit_n opium_n etc._n etc._n do_v cause_n a_o more_o permanent_a and_o notable_a gaity_n pleasantness_n good_a humour_n serenity_n promptitude_n ovation_n of_o the_o spirit_n or_o sensitive_a soul_n bravery_n courage_n magnanimity_n euphory_n or_o easy_a undergo_n of_o business_n relaxation_n with_o all_o its_o effect_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o papilla_fw-la perspiration_n etc._n etc._n which_o be_v hardly_o note_v in_o other_o short_a pleasure_n unless_o it_o be_v in_o that_o eminent_a though_o short_a one_o of_o venus_n which_o be_v a_o pleasure_n of_o the_o same_o sense_n of_o feel_v as_o that_o of_o opium_n and_o wine_n be_v therefore_o please_v the_o stomach_n be_v one_o of_o the_o great_a thing_n to_o be_v regard_v in_o the_o practice_n of_o physic_n to_o comfort_n satisfy_v or_o compose_v the_o spirit_n by_o which_o mean_n i_o have_v often_o perform_v such_o cure_n that_o neither_o i_o nor_o i_o suppose_v any_o other_o can_v otherwise_o perform_v namely_o dejection_n of_o appetite_n untowardness_n at_o stomach_n etc._n etc._n when_o all_o the_o ordinary_a and_o usual_a mean_n have_v fail_v by_o ask_v they_o what_o they_o most_o desire_a or_o long_v for_o and_o let_v they_o have_v it_o or_o if_o they_o can_v not_o tell_v of_o any_o thing_n that_o they_o long_v for_o i_o have_v mention_v to_o they_o all_o the_o relish_v thing_n that_o i_o can_v think_v of_o and_o such_o as_o be_v grateful_a to_o the_o stomach_n till_o they_o fasten_v upon_o somewhat_o that_o they_o like_v or_o fancy_v and_o then_o be_v give_v they_o it_o general_o have_v the_o desire_a success_n the_o stomach_n be_v grieve_v for_o it_o will_v concern_v we_o to_o know_v how_o because_o opium_n cause_v vomit_v etc._n etc._n general_o speak_v 1._o by_o thing_n hard_a of_o digestion_n as_o heavy_a bread_n mushroom_n rosin_n and_o such_o like_a 2._o by_o thing_n acrimonious_a or_o pungent_a as_o vomitory_n of_o asarabacca_n groundsil_n squill_n etc._n etc._n which_o abound_v with_o volatile_a salt_n 3._o by_o thing_n that_o stick_v to_o the_o stomach_n which_o
by_o diminish_v or_o disable_n the_o spirit_n except_o it_o be_v that_o the_o pernicious_a rosin_n may_v do_v something_o of_o that_o kind_n by_o its_o aforesaid_a ill_a effect_n but_o by_o pleasant_o affect_v the_o membrane_n at_o stomach_n venereal_a part_n etc._n etc._n 2._o that_o sleep_n be_v cause_v by_o relaxation_n and_o quiet_v the_o spirit_n 3._o that_o pleasure_n especial_o if_o intense_a and_o last_a as_o that_o by_o opium_n comfort_n enlivens_fw-la encourage_v and_o cause_v a_o ovation_n of_o the_o sensitive_a soul_n and_o spirit_n and_o displeasure_n cause_v sadness_n dejection_n etc._n etc._n 4._o how_o pleasure_n must_v cause_v complacency_n satisfaction_n content_a acquiescence_n and_o composure_n of_o the_o sensitive_a soul_n and_o spirit_n as_o grievance_n cause_v the_o contrary_n 5._o how_o pleasure_n elevate_a and_o keep_v up_o the_o spirit_n and_o cause_v a_o entire_a relaxation_n of_o the_o defensive_a and_o a_o great_a relaxation_n of_o the_o vigilative_a contraction_n which_o tire_v the_o sensitive_a soul_n must_v cause_v euphory_n or_o easy_a undergo_n of_o labour_n journey_n etc._n etc._n without_o lassitude_n as_o experience_n show_v 6._o how_o pleasure_n cause_v relaxation_n of_o all_o the_o sensile_a part_n 7._o how_o the_o say_a relaxation_n as_o in_o sleep_n do_v by_o suffer_v the_o animal_n spirit_n to_o expand_v and_o thereby_o make_v they_o unfit_a to_o carry_v impression_n smart_o which_o be_v necessary_a to_o convey_v a_o sense_n of_o pain_n for_o a_o smart_a impression_n be_v the_o very_a cause_n of_o it_o take_v away_o pain_n to_o which_o you_o may_v add_v that_o the_o sensitive_a soul_n attend_v willing_o to_o the_o sense_n of_o pleasure_n be_v divert_v from_o pain_n and_o that_o a_o sense_n of_o pain_n can_v be_v in_o the_o same_o subject_a with_o pleasure_n which_o be_v therefore_o once_o excite_v pain_n must_v disappear_v but_o that_o of_o take_v away_o all_o smartness_n of_o impression_n by_o relaxation_n be_v a_o plain_a mechanical_a cause_n 8._o how_o therefore_o all_o flux_n that_o be_v cause_v by_o or_o require_v a_o grievous_a sensation_n or_o irritation_n by_o quantity_n or_o quality_n to_o maintain_v and_o continue_v they_o by_o cause_v a_o contraction_n of_o the_o part_n to_o squeeze_v out_o the_o humour_n must_v be_v moderate_v for_o want_v of_o sensation_n upon_o such_o relaxation_n to_o irritate_fw-la the_o part_n as_o it_o happen_v in_o sleep_n or_o in_o any_o case_n where_o relaxation_n and_o thereby_o expansion_n of_o the_o animal_n spirit_n incapacitates_fw-la they_o to_o carry_v impression_n smart_o which_o be_v of_o the_o essence_n of_o pain_n as_o have_v be_v show_v 9_o how_o perspiration_n must_v be_v promote_v by_o relaxation_n which_o open_v the_o pore_n 10._o how_o that_o by_o the_o same_o mean_n sweat_v also_o must_v be_v promote_v if_o the_o body_n be_v full_a of_o moisture_n 11._o how_o opium_n or_o semen_n animale_a be_v of_o the_o same_o principle_n and_o of_o like_a principle_n with_o cantharides_n pismire_n bee_n garlick_n etc._n etc._n must_v excite_v to_o venery_n cause_n itch_n of_o the_o skin_n etc._n etc._n 12._o how_o opium_n may_v by_o too_o high_a a_o ovation_n of_o the_o spirit_n cause_n watch_v while_o pleasure_n cause_v relaxation_n etc._n etc._n may_v take_v away_o pain_n for_o relaxation_n as_o in_o sleep_n syncopes_fw-la etc._n etc._n be_v enough_o to_o take_v away_o pain_n but_o to_o sleep_v quietness_n of_o the_o spirit_n be_v also_o require_v as_o well_o as_o their_o expansion_n by_o relaxation_n so_o that_o pain_n may_v very_o well_o be_v take_v off_o without_o sleep_n as_o it_o often_o be_v by_o opium_n that_o always_o relax_n 13._o how_o the_o pleasure_n that_o opium_n cause_n be_v as_o be_v say_v by_o the_o same_o principle_n and_o therefore_o of_o the_o same_o nature_n with_o that_o which_o animal_n seed_n cause_v upon_o the_o membrane_n but_o that_o animal_n seed_n cause_v it_o only_o upon_o one_o part_n and_o opium_n upon_o the_o membrane_n of_o the_o stomach_n venereal_a part_n and_o all_o other_o in_o general_n and_o that_o only_a for_o a_o moment_n but_o this_o of_o opium_n for_o many_o hour_n by_o which_o mean_v the_o effect_n of_o relaxtion_n by_o pleasure_n come_v to_o be_v more_o remarkable_a as_o after_o much_o wine_n who_o effect_n be_v somewhat_o last_v and_o internal_a as_o that_o of_o opium_n be_v 14._o how_o the_o rosin_n of_o opium_n cause_v its_o ill_a effect_n by_o its_o indigestibleness_n adhere_v quality_n and_o tedious_a sting_a of_o the_o exquisite_o nice_a coat_n of_o the_o stomach_n by_o continual_o teaze_v and_o urge_v it_o by_o its_o actimony_n and_o acute_a volatile_a point_n or_o spiculâ—_n therefore_o have_v 1._o a_o most_o perfect_a and_o complete_a sol-volatile-oleosum_a in_o opium_n of_o the_o same_o please_a principle_n as_o to_o all_o membrane_n as_o animal_n seed_n be_v to_o the_o membrane_n of_o venus_n whereby_o they_o must_v be_v please_v tickle_v and_o relax_v 2._o a_o pernicious_a rosin_n indigestible_a stick_v and_o arm_v with_o acrimonious_a and_o sting_a point_n which_o must_v high_o offend_v the_o most_o sensile_a coat_n at_o the_o stomach_n i_o be_o now_o ready_a by_o god_n assistance_n to_o explain_v every_o phenomenon_n or_o effect_v of_o opium_n however_o amaze_a and_o mysterious_a hope_v they_o will_v not_o remain_v long_o so_o chap._n xvi_o the_o explication_n of_o the_o effect_n of_o opium_n use_v external_o its_o effect_n external_o use_v be_v of_o two_o sort_n either_o i._o as_o a_o opiate_n or_o please_a tickler_n of_o the_o membrane_n or_o ii_o as_o a_o alterative_a of_o the_o part_n that_o it_o be_v apply_v to_o first_o as_o a_o opiate_n or_o pleaser_n of_o the_o membrane_n it_o have_v the_o same_o effect_n as_o opium_n use_v internal_o and_o for_o the_o same_o reason_n therefore_o the_o cause_n of_o its_o operation_n in_o this_o case_n will_v be_v better_o see_v by_o the_o explication_n of_o its_o internal_a effect_n which_o be_v far_o more_o perfect_a complete_a and_o certain_a second_o as_o a_o alterative_a of_o the_o part_n that_o it_o be_v apply_v to_o which_o be_v the_o follow_v viz._n 1._o it_o incides_fw-la resolve_n and_o discuss_n by_o its_o point_a penetrate_a and_o volatile_a salt_n insinuate_v itself_o into_o the_o part_n and_o humour_n of_o the_o animal_n because_o its_o particle_n be_v fine_a minute_n and_o agreeable_a thereto_o as_o menstruum_n to_o the_o thing_n to_o be_v dissolve_v then_o by_o its_o volatility_n it_o discuss_n what_o it_o have_v so_o incide_v and_o resolve_v 2._o it_o mollefy_v and_o relax_n by_o its_o sal-volatile-oleosum_a so_o resolve_v the_o part_n and_o humour_n and_o thereby_o kindly_a loosen_a they_o thus_o opiate_n as_o solanum_fw-la lethale_n or_o deadly_a night_n shade_n hemlock_n mandrake_n etc._n etc._n come_v to_o be_v of_o excellent_a use_n in_o hard_a tumor_n of_o the_o spleen_n tophousness_n etc._n etc._n 3._o it_o maturate_v and_o suppurate_v for_o the_o aforesaid_a reason_n for_o nothing_o can_v better_v dispose_n towards_o maturation_n and_o suppuration_n than_o relax_v mollefy_a and_o resolve_v 4._o it_o exulcerate_v or_o cause_n blister_n or_o at_o least_o rubify_v tender_a skin_n if_o it_o be_v very_o strong_a because_o of_o its_o volatile_a salt_n as_o cantharides_n spearwort_n and_o other_o thing_n do_v upon_o the_o same_o account_n but_o this_o effect_n belong_v main_o to_o the_o true_a mastack_n or_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o drop_n from_o the_o incision_n make_v in_o the_o head_n of_o the_o poppy_n more_o especial_o the_o theban_a which_o afford_v a_o most_o powerful_a juice_n for_o exulcerate_v or_o blister_v be_v but_o a_o strong_a full_a and_o therefore_o painful_a resolution_n as_o you_o see_v by_o the_o cuticle_n upon_o blister_n resolve_v into_o a_o kind_n of_o jelly_n 5._o it_o be_v psilothrick_n for_o the_o same_o reason_n for_o while_o it_o so_o resolve_v the_o part_n it_o loosen_v the_o root_n of_o the_o hair_n and_o so_o cause_v its_o shed_n 6._o it_o hurt_v the_o eye_n because_o of_o its_o acrimony_n by_o reason_n of_o the_o volatile_a salt_n 7._o it_o cause_v itch_a in_o the_o skin_n by_o the_o titillation_n of_o the_o same_o volatile_a salt_n as_o you_o find_v by_o the_o application_n of_o squill_n and_o the_o like_a 8._o it_o excite_v venery_n by_o the_o same_o titillation_n on_o the_o veneral_a membrane_n chap._n xvii_o the_o explication_n of_o the_o effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v note_v that_o because_o opium_n have_v be_v general_o hitherto_o use_v either_o crude_a or_o with_o its_o rosin_n in_o it_o the_o effect_n of_o opium_n be_v according_o consider_v as_o common_a experience_n thereupon_o have_v give_v opportunity_n of_o observe_v they_o but_o as_o i_o proceed_v i_o shall_v show_v you_o where_o the_o resinous_n part_n of_o opium_n be_v concern_v in_o the_o effect_n 1._o it_o be_v manifest_a why_o opium_n may_v well_o
contract_v it_o be_v round_o even_o polite_a and_o true_o represent_v thing_n 11._o deadness_n of_o the_o eye_n to_o the_o view_n be_v as_o have_v be_v show_v from_o the_o laxity_n of_o the_o cornea_n which_o make_v it_o flag_n lie_v loose_a look_v dull_o and_o not_o due_o reflect_v a_o smart_n and_o brisk_a speck_n of_o light_n as_o it_o do_v when_o tense_n round_o and_o polite_a by_o its_o contraction_n on_o the_o contain_v humour_n which_o then_o due_o fill_v it_o 12._o falter_v of_o the_o tongue_n be_v from_o the_o same_o relaxation_n as_o in_o drunken_a person_n 13._o a_o sopor_fw-la be_v from_o the_o same_o relaxation_n over_o all_o the_o sensile_a part_n of_o the_o body_n by_o which_o mean_v sense_n and_o motion_n be_v diminish_v or_o lose_v by_o the_o expansion_n of_o the_o animal_n spirit_n which_o as_o have_v be_v say_v be_v not_o due_o compress_v become_v unfit_a for_o both_o at_o the_o same_o time_n 14._o a_o slow_a and_o wide_a pulse_n be_v from_o the_o same_o cause_n because_o the_o say_a relaxation_n permit_v the_o artery_n to_o widen_v and_o the_o animal_n spirit_n to_o expand_v and_o consequent_o render_v the_o motion_n of_o the_o heart_n slow_a which_o be_v the_o cause_n of_o the_o pulse_n 15._o a_o high_a colour_n or_o efflorescence_n of_o the_o skin_n have_v be_v explain_v 16._o looseness_n of_o the_o jaw_n and_o lip_n be_v from_o the_o same_o relaxation_n as_o be_v show_v and_o so_o be_v 17._o intumescence_n of_o the_o lip_n as_o have_v be_v show_v 18._o difficulty_n of_o breathe_v may_v be_v from_o two_o different_a cause_n either_o by_o the_o relaxation_n weaken_v the_o requisite_a motion_n for_o want_n of_o compressure_n of_o the_o animal_n spirit_n and_o by_o the_o flaccity_n of_o the_o part_n themselves_o or_o by_o a_o great_a grievance_n at_o stomach_n upon_o the_o account_n of_o the_o rosin_n stick_v to_o it_o and_o cause_v a_o convulsion_n of_o those_o part_n both_o which_o may_v happen_v 19_o fury_n and_o madness_n may_v also_o happen_v either_o by_o the_o exalt_a pleasure_n of_o its_o titillation_n as_o in_o drunkard_n who_o therefore_o scarce_o know_v what_o they_o do_v the_o mind_n be_v as_o be_v say_v alienate_v or_o it_o may_v happen_v as_o i_o have_v often_o know_v a_o kind_n of_o madness_n to_o be_v produce_v by_o a_o great_a grievance_n at_o stomach_n which_o may_v well_o be_v from_o the_o rosin_n grieve_v and_o teaze_v the_o nice_o sensile_a stomach_n they_o may_v be_v easy_o distinguish_v one_o viz._n that_o from_o the_o rosin_n at_o stomach_n be_v with_o great_a distress_n anxiety_n convulsion_n etc._n etc._n and_o the_o other_o without_o any_o 20._o venereal_a fury_n proceed_v from_o the_o high_a titillation_n of_o the_o venereal_a membrane_n by_o the_o volatile_a salt_n of_o so_o much_o opium_n as_o if_o cantharides_n bee_n &c_n &c_n be_v take_v internal_o but_o that_o these_o can_v so_o agreeable_o titillate_v those_o part_n as_o opium_n do_v who_o volatile_a particle_n be_v render_v more_o please_a by_o oily_a one_o and_o therefore_o much_o of_o the_o nature_n of_o semen_n virile_a 21._o priapism_n be_v cause_v by_o the_o same_o continual_a titillation_n 22._o violent_a itch_n of_o the_o skin_n be_v cause_v by_o the_o same_o tickle_a volatile_a particle_n in_o great_a abundance_n proportionable_a to_o the_o excessive_a do_v 23._o nauseas_fw-la be_v cause_v by_o the_o rosin_n stick_v at_o and_o solicit_v the_o stomach_n to_o vomit_v 24._o swimmings_n in_o the_o head_n be_v by_o conseâ—it_n because_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o be_v observe_v in_o many_o case_n from_o a_o grieve_a stomach_n upon_o a_o tendency_n to_o vomit_v as_o when_o it_o be_v overload_v with_o wine_n or_o indigestible_a victual_n or_o when_o person_n be_v sea_n or_o coach-sick_a etc._n etc._n for_o it_o be_v not_o in_o these_o last_o case_n because_o the_o brain_n be_v offend_v as_o people_n imagine_v that_o they_o be_v sick_a or_o vomit_n but_o the_o swim_v in_o the_o head_n and_o offence_n of_o the_o brain_n happen_v because_o the_o stomach_n be_v offend_v by_o the_o motion_n of_o the_o coach_n or_o ship_n by_o reason_n of_o its_o most_o exquisite_a sensation_n which_o the_o effluvias_fw-la of_o a_o cat_n pestiferous_a particle_n and_o commotion_n cause_v by_o mear_v passion_n can_v and_o do_v offend_v as_o be_v say_v so_o as_o to_o cause_v vomit_n anxiety_n etc._n etc._n much_o more_o than_o may_v the_o motion_n of_o a_o ship_n or_o coach_n do_v it_o i_o shall_v not_o here_o enter_v into_o controversy_n with_o those_o that_o assert_v that_o it_o be_v the_o head_n be_v first_o offend_v in_o a_o coach_n or_o ship_n it_o be_v sufficient_a for_o my_o purpose_n that_o grievance_n at_o stomach_n do_v common_o cause_n swimmings_n in_o the_o head_n for_o take_v off_o those_o grievance_n cure_v they_o as_o eat_v when_o it_o be_v from_o the_o grievance_n of_o hunger_n or_o wind_n at_o stomach_n and_o discharge_v the_o stomach_n of_o a_o great_a load_n of_o wine_n ale_z or_o indigestible_a matter_n when_o such_o thing_n cause_v it_o do_v cure_v such_o swimming_n in_o the_o head_n the_o way_n how_o grievance_n at_o stomach_n do_v cause_n those_o swimming_n be_v by_o cause_v a_o contraction_n as_o all_o grievance_n do_v but_o especial_o those_o at_o stomach_n of_o the_o membrane_n of_o the_o brain_n as_o it_o do_v of_o all_o other_o but_o main_o of_o these_o because_o very_o sensile_a by_o which_o mean_v the_o animal_n spirit_n be_v compress_v grow_v more_o irrequiete_a and_o skip_a up_o and_o down_o and_o the_o compression_n not_o be_v continual_o alike_o in_o general_n or_o the_o artery_n afford_v a_o uneven_a and_o forcible_a supply_n of_o they_o or_o fume_n from_o the_o blood_n by_o the_o compression_n nor_o affect_v all_o part_n of_o the_o brain_n with_o equal_a force_n because_o the_o pleasure_n endeavour_n to_o relax_v etc._n etc._n there_o must_v thence_o arise_v eddy_n vortices_fw-la or_o whirl_v thereof_o which_o cause_n swimmings_n vertigo_n &c._n &c._n according_a as_o they_o happen_v to_o be_v move_v that_o they_o happen_v from_o such_o contraction_n be_v manifest_a 1._o because_o the_o grievance_n at_o stomach_n can_v add_v nothing_o else_o to_o the_o brain_n or_o its_o membrane_n 2._o because_o they_o be_v take_v off_o by_o please_v the_o stomach_n and_o consequent_o by_o relaxation_n as_o by_o a_o glass_n of_o wine_n victual_n a_o opiate_n that_o be_v not_o resinous_a etc._n etc._n it_o be_v here_o well_o worth_a your_o notice_n that_o all_o consent_n of_o part_n a_o thing_n much_o admire_v be_v only_o by_o contraction_n or_o relaxation_n which_o sudden_o affect_v the_o whole_a systeme_n of_o the_o nerve_n and_o membrane_n 25._o vertigo_n be_v from_o the_o same_o cause_n 26._o vomit_n be_v cause_v as_o be_v say_v by_o the_o great_a grievance_n of_o the_o acrimonious_a rosin_n stick_v to_o the_o coat_n of_o the_o stomach_n 27._o hiccongh_n be_v from_o the_o same_o cause_n which_o happen_v upon_o the_o decay_n of_o power_n vigorous_o to_o vomit_v dwindle_v into_o those_o fruitless_a convulsive_a subsultory_n jerâ—_n or_o half_a endeavour_n 28._o distress_n and_o anxiety_n must_v necessary_o attend_v such_o a_o grievous_a sensation_n and_o desection_n of_o nature_n endeavour_v as_o be_v overbear_v and_o disable_v to_o work_v for_o itself_o 29._o a_o turbulent_a pulse_n must_v be_v a_o effect_n of_o the_o forego_n tumult_n 30._o convulsion_n happen_v as_o be_v show_v by_o the_o enormous_a compression_n of_o the_o animal_n spirit_n by_o reason_n of_o the_o violent_a contraction_n upon_o the_o great_a grievance_n by_o the_o rosin_n at_o stomach_n which_o cause_v they_o to_o skip_v and_o fling_v up_o and_o down_o very_o forcible_o under_o the_o squeeze_v of_o the_o compression_n and_o possible_o skirmish_v under_o the_o vicissitude_n of_o it_o and_o relaxation_n 31._o faint_n and_o leipothymy_n be_v cause_v as_o have_v be_v explain_v by_o the_o sensitive_a soul_n be_v overtired_n by_o the_o fatigue_n of_o defensive_a contraction_n and_o yield_v himself_o to_o rest_n from_o all_o contraction_n as_o the_o last_o relief_n etc._n etc._n whereupon_o sense_n and_o motion_n do_v fail_v for_o want_v of_o compression_n to_o render_v the_o spirit_n springy_a active_a and_o fit_a for_o the_o purpose_n 32._o cold_a breath_n be_v but_o a_o necessary_a consequence_n of_o the_o loss_n of_o motion_n and_o therefore_o of_o heat_n by_o such_o leipothymy_n and_o faint_n 33._o death_n be_v cause_v two_o manner_n of_o way_n that_o be_v either_o by_o a_o utter_a expense_n of_o spirit_n and_o thereupon_o a_o dereliction_n or_o extinction_n of_o the_o sensitive_a soul_n by_o reason_n of_o those_o distress_n and_o fatigue_n upon_o the_o account_n of_o the_o invincible_a rosin_n or_o by_o too_o much_o relaxation_n disable_n all_o the_o motion_n of_o the_o body_n as_o in_o such_o as_o die_v be_v dead_a drink_v
that_o include_v the_o glandule_n must_v as_o in_o sleep_n which_o relax_n they_o stop_v or_o moderate_v all_o defluxion_n catarrh_n etc._n etc._n because_o they_o be_v not_o sensible_a oâ—_n the_o irritation_n of_o the_o humour_n by_o quantity_n or_o quality_n which_o irritation_n cause_v the_o defluxion_n or_o catarrh_n by_o exciting_a the_o membrane_n to_o contract_v and_o thereby_o to_o squeeze_v out_o the_o humour_n contain_v in_o the_o glandule_n four_o the_o composure_n of_o the_o spirit_n be_v procure_v main_o by_o sleep_n which_o all_o loss_n of_o spirit_n as_o be_v show_v incline_v we_o to_o so_o bleed_v which_o diminish_v the_o spirit_n compose_v their_o fury_n in_o fever_n delirium_n madness_n etc._n etc._n five_o perspiration_n be_v cause_v by_o nothing_o more_o than_o sleep_v for_o we_o perspire_v twice_o as_o much_o in_o sleep_n as_o when_o we_o watch_v as_o be_v most_o manifest_o demonstrable_a by_o the_o statick_a experiment_n of_o weigh_v people_n nor_o be_v perspiration_n ever_o so_o great_a as_o in_o deliquium_n syncopes_fw-la leipothymy_n and_o such_o like_a deadish_fw-mi case_n which_o be_v cause_v by_o diminish_v or_o disable_n of_o the_o spirit_n nay_o it_o be_v so_o in_o animal_n quite_o dead_a for_o a_o little_a time_n while_o they_o be_v hot_a as_o be_v evident_a by_o like_a statick_a demonstration_n the_o true_a cause_n of_o which_o be_v relaxation_n of_o the_o pore_n skin_n etc._n etc._n for_o want_n of_o spirit_n to_o contract_n and_o constringe_v they_o as_o shall_v be_v full_o prove_v hereafter_o by_o god_n help_n these_o thing_n be_v doubtless_o the_o occasion_n of_o that_o hypothesis_n of_o diminish_v or_o disable_n the_o spirit_n by_o opium_n but_o how_o likely_a be_v they_o to_o err_v by_o establish_v it_o without_o any_o consideration_n of_o its_o enliven_a encourage_v and_o brisk_a effect_n as_o ovation_n of_o the_o spirit_n gaity_n bravery_n magnanimity_n euphory_n promptitude_n to_o venery_n etc._n etc._n which_o can_v never_o be_v solve_v by_o diminution_n or_o disability_n of_o the_o spirit_n till_o depression_n and_o elevation_n thereof_o be_v reconcilable_a and_o consistent_a at_o the_o same_o time_n in_o the_o same_o subject_n which_o can_v never_o be_v till_o disable_n and_o not_o disable_n be_v the_o same_o thing_n have_v not_o we_o then_o good_a reason_n to_o suspect_v that_o general_a foundation_n of_o diminish_v or_o disable_n the_o spirit_n by_o opium_n which_o be_v lay_v by_o such_o as_o never_o consider_v any_o thing_n of_o its_o generous_a and_o sprightly_a effect_n which_o as_o have_v be_v show_v be_v its_o constant_a and_o therefore_o most_o proper_a and_o genuine_a effect_n who_o can_v doubt_v then_o but_o they_o must_v err_v in_o lay_v a_o foundation_n quite_o contrary_a to_o the_o very_a property_n of_o opium_n 5._o i_o observe_v that_o all_o our_o modern_a author_n and_o physician_n receive_v the_o knowledge_n of_o opium_n its_o effect_n and_o uses_n from_o those_o ancient_n do_v use_v it_o only_o for_o the_o same_o end_n and_o purpose_v as_o they_o do_v and_o that_o our_o modern_a author_n live_v in_o these_o western_a part_n of_o the_o world_n very_o remote_a from_o the_o eastern_a country_n where_o it_o be_v use_v common_o and_o in_o large_a dose_n by_o people_n in_o health_n in_o the_o daytime_n to_o enliven_v invigorate_a and_o encourage_v they_o and_o cause_v the_o brave_a generous_a and_o magnanimous_a effect_n aforemention_v viz._n courage_n euphory_n etc._n etc._n and_o find_v no_o physician_n that_o go_v before_o they_o to_o mention_v these_o noble_a cordial_a and_o glorious_a effect_n and_o if_o they_o do_v at_o any_o time_n slight_o touch_v they_o to_o do_v it_o with_o all_o imaginable_a disregard_n neglect_v and_o contempt_n as_o if_o there_o be_v no_o heed_n to_o be_v take_v of_o they_o but_o as_o idle_a tale_n and_o improbable_a story_n be_v contrary_a and_o utter_o as_o they_o think_v inconsistent_a and_o irreconcilable_a with_o the_o daily_a and_o most_o notorious_a effect_n of_o opium_n observe_v among_o we_o and_o to_o the_o universal_a opinion_n of_o all_o author_n who_o state_v opium_n to_o be_v a_o diminisher_n or_o disabler_n of_o the_o spirit_n which_o can_v not_o produce_v as_o they_o conclude_v such_o contradictory_n and_o therefore_o to_o they_o utter_o incredible_a effect_n and_o fabulons_a flam_n arise_v as_o they_o fancy_v from_o some_o silly_a error_n as_o want_v of_o due_a observation_n in_o traveller_n mistake_a discourse_n and_o the_o like_a so_o that_o as_o the_o say_n be_v they_o let_v they_o in_o at_o one_o ear_n and_o out_o at_o the_o other_o there_o be_v no_o such_o contrary_a effect_n of_o any_o one_o thing_n to_o be_v observe_v in_o the_o whole_a creation_n and_o they_o be_v well_o assure_v of_o the_o other_o effect_n by_o daily_a experience_n and_o have_v never_o observe_v those_o lively_a effect_n for_o the_o several_a plain_a reason_n that_o you_o will_v meet_v in_o the_o follow_a paragraph_n have_v no_o cause_n to_o alter_v their_o opinion_n when_o all_o thing_n seem_v to_o they_o to_o make_v for_o their_o hypothesis_n for_o want_v of_o a_o notion_n of_o those_o brisk_a effect_n 6._o i_o observe_v that_o those_o brisk_a effect_n of_o opium_n be_v not_o take_v notice_n of_o by_o our_o physician_n nor_o indeed_o all_o thing_n consider_v do_v i_o well_o see_v how_o they_o shall_v without_o get_v out_o of_o the_o common_a road_n of_o observe_v which_o be_v sometime_o as_o i_o have_v find_v very_o useful_a upon_o such_o occasion_n for_o first_o opium_n be_v seldom_o if_o ever_o give_v in_o these_o western_a nation_n but_o to_o sick_a people_n as_o the_o ancient_n do_v who_o be_v utter_o incapable_a of_o those_o brisk_a effect_n or_o at_o least_o to_o any_o remarkable_a degree_n that_o may_v call_v for_o a_o particular_a or_o special_a advertency_n or_o attention_n without_o which_o they_o pass_v off_o as_o they_o come_v without_o any_o reflection_n thereupon_o and_o so_o signify_v nothing_o as_o if_o they_o have_v never_o happen_v second_o we_o as_o the_o ancient_n do_v general_o give_v opium_n when_o people_n be_v go_v to_o bed_n by_o which_o mean_v all_o opportunity_n of_o observation_n be_v lose_v because_o darkness_n and_o be_v alone_o hide_v or_o hinder_v the_o show_v of_o any_o such_o effect_n and_o the_o physician_n who_o only_a business_n it_o be_v to_o be_v more_o curious_a in_o such_o matter_n be_v go_v to_o his_o own_o rest_n though_o if_o he_o be_v present_a not_o likely_a to_o take_v any_o observation_n of_o such_o matter_n whereof_o he_o have_v least_o thought_n or_o belief_n as_o be_v in_o his_o opinion_n contrary_a to_o all_o reason_n sense_n experience_n and_o the_o opinion_n of_o all_o author_n of_o the_o stupefactive_a quality_n of_o opium_n in_o which_o they_o all_o agree_v three_o opium_n be_v as_o be_v say_v give_v in_o these_o country_n to_o cause_n sleep_n or_o such_o effect_n to_o which_o sleep_n conduce_v as_o compose_v the_o spirit_n cause_v indolence_n stop_v flux_n and_o promote_a perspiration_n and_o therefore_o always_o give_v with_o all_o careful_a direction_n and_o injunction_n that_o may_v conduce_v to_o that_o end_n as_o go_v to_o bed_n lie_v still_o put_v out_o light_n keep_v silence_n etc._n etc._n which_o concur_v with_o the_o opium_n cause_n sleep_n which_o be_v utter_o inconsistent_a with_o show_v any_o of_o those_o lively_a effect_n that_o belong_v only_o to_o a_o wake_a person_n to_o do_v so_o that_o all_o opportunity_n of_o observation_n be_v utter_o preclude_v now_o all_o the_o premise_n consider_v it_o can_v be_v conceive_v that_o such_o as_o set_v their_o mind_n upon_o contrary_a effect_n and_o expect_v no_o other_o much_o less_o contrary_a one_o against_o which_o also_o they_o be_v high_o prejudice_v by_o their_o reason_n experience_n and_o read_v shall_v observe_v such_o brisk_a effect_n if_o they_o do_v happen_v and_o how_o can_v a_o brisk_a humour_n courage_n easy_a undergo_n of_o labour_n promptitude_n to_o venus_n etc._n etc._n be_v observe_v in_o sick_a and_o infirm_a people_n lie_v in_o bed_n alone_z and_o in_o the_o dark_a or_o which_o render_v it_o utter_o impossible_a while_o they_o be_v asleep_a and_o the_o thing_n itself_o disbelieved_a and_o esteem_v contrary_a to_o common_a sense_n and_o the_o universal_a sentiment_n of_o the_o learned_a and_o all_o other_o therefore_o 7._o if_o after_o all_o any_o such_o brisk_a effect_n do_v ever_o happen_v it_o must_v be_v either_o not_o regard_v or_o if_o observe_v which_o be_v no_o way_n likely_a as_o be_v show_v you_o may_v be_v sure_a for_o the_o many_o plain_a reason_n and_o cause_n aforesaid_a that_o it_o be_v not_o impute_v to_o stupify_a opium_n as_o all_o esteem_v it_o but_o to_o any_o other_o cause_n or_o accident_n rather_o than_o to_o a_o thing_n well_o know_v to_o have_v quite_o contrary_a effect_n for_o instance_n if_o the_o sick_a person_n happen_v to_o be_v
good_a humour_a of_o which_o he_o be_v seldom_o capable_a and_o utter_o incapable_a of_o all_o or_o most_o of_o the_o other_o brisk_a effect_n as_o euphory_n promptitude_n to_o venus_n exertion_n of_o courage_n etc._n etc._n it_o be_v either_o pass_v by_o as_o a_o ordinary_a thing_n of_o course_n and_o so_o not_o heed_v or_o else_o impute_v to_o refreshment_n by_o sleep_n ease_n from_o pain_n or_o some_o amendment_n as_o to_o the_o disease_n or_o indeed_o to_o any_o thing_n rather_o than_o dispiriting_n and_o stupify_a opium_n that_o be_v so_o far_o in_o all_o opinion_n from_o exciting_a the_o spirit_n that_o all_o affirm_v conclude_v and_o agree_v that_o it_o diminish_v or_o disable_v they_o the_o like_a be_v to_o be_v say_v of_o any_o of_o the_o lively_a effect_n in_o case_n they_o happen_v and_o be_v observe_v though_o i_o do_v not_o see_v how_o they_o can_v so_o at_o least_o as_o any_o slander_n by_o will_v refer_v it_o to_o opium_n beside_o that_o as_o to_o some_o of_o the_o brisk_a effect_n especial_o that_o of_o venery_n great_a dose_n be_v requisite_a to_o render_v it_o any_o thing_n remarkable_a than_o be_v use_v in_o these_o western_a part_n and_o that_o modesty_n will_v much_o hinder_v the_o discovery_n of_o this_o effect_n be_v it_o not_o therefore_o very_o manifest_a that_o i_o have_v great_a cause_n to_o suspect_v that_o both_o ancient_n and_o modern_a physician_n consider_v thing_n by_o half_n since_o they_o do_v not_o take_v the_o most_o genuine_a property_n into_o their_o consideration_n and_o that_o they_o lay_v their_o foundation_n upon_o the_o most_o contrary_a effect_n to_o they_o it_o follow_v then_o that_o the_o general_a supposition_n of_o all_o the_o learned_a can_v no_o more_o solve_v the_o true_a property_n of_o opium_n in_o any_o probability_n than_o give_v the_o reason_n why_o fire_n harden_v clay_n can_v explain_v why_o it_o soften_v wax_n the_o reason_n do_v i_o say_v i_o shall_v have_v say_v than_o give_v the_o wrong_a reason_n why_o it_o harden_v clay_n show_v how_o it_o soften_v wax_n for_o it_o will_v appear_v in_o the_o follow_a chapter_n that_o they_o give_v no_o right_a reason_n for_o any_o effect_n of_o opium_n even_o those_o they_o ever_o allow_v to_o be_v its_o effect_n nor_o lay_v any_o true_a foundation_n to_o explain_v the_o least_o mean_a and_o plain_a effect_n thereof_o forasmuch_o as_o all_o their_o supposition_n be_v so_o false_a that_o there_o never_o be_v any_o such_o thing_n as_o they_o lie_v down_o to_o explain_v the_o effect_n of_o opium_n viz._n 1._o no_o such_o thing_n as_o a_o cold_a quality_n in_o opium_n 2._o no_o such_o thing_n as_o fume_n etc._n etc._n fly_v from_o opium_n to_o the_o brain_n while_o it_o be_v at_o stomach_n 3._o no_o such_o thing_n as_o diminish_v or_o disable_n the_o animal_n spirit_n by_o opium_n any_o way_n whatsoever_o of_o which_o in_o their_o order_n in_o the_o follow_a chapter_n chap._n ix_o it_o be_v prove_v that_o opium_n have_v no_o cold_a quality_n to_o diminish_v or_o disable_v the_o spirit_n thereby_o have_v show_v just_a cause_n of_o my_o suspicion_n of_o that_o universal_a foundation_n of_o opium_n diminish_v or_o disable_n the_o spirit_n i_o will_v now_o proceed_v to_o a_o more_o strict_a examination_n thereof_o beginning_n with_o the_o opinion_n of_o the_o ancient_n who_o affirm_v that_o opium_n diminish_v or_o disable_v the_o spirit_n by_o a_o extreme_a cold_a quality_n i_o confess_v that_o much_o may_v be_v do_v towards_o the_o diminish_n or_o disable_n the_o spirit_n by_o opium_n if_o it_o have_v such_o a_o cold_a quality_n as_o the_o ancient_n attribute_v to_o it_o for_o than_o it_o must_v be_v such_o a_o coldness_n as_o the_o cold_a thing_n either_o actual_a or_o potential_a bear_v no_o proportion_n to_o for_o ice_n snow_n etc._n etc._n bear_v no_o proportion_n to_o it_o in_o cause_v the_o same_o effect_n by_o a_o cold_a quality_n it_o be_v the_o manner_n of_o the_o ancient_n implicit_o to_o believe_v and_o subscribe_v to_o what_o their_o great_a author_n and_o master_n in_o physic_n or_o philosophy_n teach_v they_o who_o they_o adore_v as_o infallible_a god_n as_o soon_o as_o their_o mortality_n prove_v the_o contrary_a which_o be_v as_o absurd_a as_o assert_v tha_z opium_n which_o be_v one_o of_o the_o hot_a thing_n that_o vegetable_n afford_v be_v extreme_a cold_a bless_a be_v god_n for_o our_o light_n in_o religion_n and_o liberty_n in_o philosophy_n therefore_o some_o such_o admire_a author_n or_o great_a master_n in_o physic_n have_v assert_v that_o opium_n act_v by_o a_o extreme_a cold_a quality_n all_o do_v implicit_o subscribe_v to_o it_o the_o devil_n who_o they_o worship_v can_v not_o though_o a_o deceiver_n from_o the_o beginning_n impose_v more_o upon_o their_o faith_n than_o in_o cause_v they_o for_o i_o can_v think_v but_o it_o be_v some_o such_o evil_a power_n to_o believe_v that_o opium_n be_v cold_a against_o all_o the_o evidence_n of_o sense_n and_o experience_n he_o may_v have_v as_o well_o tell_v they_o that_o hell_n fire_n have_v all_o the_o property_n of_o common_a culinary_a fire_n and_o yet_o nothing_o more_o refresh_v by_o its_o cold_a quality_n for_o as_o many_o of_o our_o sense_n as_o can_v take_v notice_n of_o heat_n and_o cold_a do_v plain_o inform_v we_o that_o it_o be_v very_o hot_a in_o itself_o and_o effect_n for_o 1._o it_o be_v taste_n be_v very_o bitter_a rank_a vehement_o hot_a burn_a and_o bite_v all_o which_o quality_n be_v infallible_a sign_n of_o great_a heat_n and_o the_o better_a the_o opium_n be_v the_o more_o intense_a be_v those_o quality_n nay_o it_o be_v observe_v that_o its_o very_a virtue_n be_v strict_o combine_v to_o or_o consist_v in_o those_o quality_n especial_o bitterness_n which_o if_o lose_v the_o virtue_n be_v go_v as_o be_v common_o observe_v and_o easy_o observable_a it_o be_v a_o wise_a fetch_v of_o amatus_fw-la lusitanus_n in_o defence_n of_o its_o cold_a quality_n to_o attribute_v all_o its_o bitterness_n to_o glaucium_fw-la that_o be_v mix_v therewith_o whereas_o glaucium_fw-la always_o give_v a_o yellow_a tincture_n to_o water_n and_o opium_n a_o red_a but_o the_o opium_n that_o give_v no_o yellow_a tincture_n be_v bitter_a also_o yea_o that_o be_v most_o bitter_a that_o give_v the_o red_a tincture_n how_o come_v theban_a opium_n and_o indeed_o all_o other_o opium_n to_o be_v bitter_a before_o any_o thing_n be_v mix_v with_o it_o how_o inadvertent_o absurd_a people_n will_v be_v to_o defend_v absurdity_n it_o be_v pretty_a to_o see_v how_o they_o will_v expose_v themselves_o to_o defend_v a_o false_a opinion_n 2._o it_o be_v smell_n which_o be_v very_a rank_n strong_a hot_a and_o such_o as_o thing_n high_o impregnate_v with_o volatile_a salt_n and_o sulphur_n the_o two_o hot_a principle_n in_o nature_n do_v afford_v it_o be_v from_o volatile_a salt_n that_o cantharides_n pismire_n spear-wort_n crowsfoot_n etc._n etc._n be_v so_o very_o hot_a as_o to_o blister_v or_o exulcerate_v and_o be_v not_o all_o hot_a spirit_n such_o upon_o the_o account_n of_o their_o sulphur_n as_o spirit_n of_o wine_n brandy_n etc._n etc._n 3._o the_o best_a and_o strong_a opium_n will_v also_o exulcerate_v as_o all_o author_n agree_v which_o only_a fire_n or_o such_o thing_n as_o have_v the_o particle_n of_o fire_n lodge_v in_o they_o as_o lixiviate_n etc._n etc._n or_o the_o hot_a thing_n in_o nature_n will_v do_v as_o cantharides_n spear-wort_n etc._n etc._n it_o be_v 4._o for_o the_o like_a reason_n a_o psilothrick_n or_o causer_n of_o hair_n to_o fall_v which_o only_a lime_n orpâ—ment_n and_o the_o hot_a thing_n do_v cause_n 5._o it_o be_v inflammable_a which_o only_o sulphurecus_fw-la thing_n be_v 6._o it_o cause_v a_o sense_n of_o a_o vehement_a heat_n at_o stomach_n though_o take_v but_o in_o the_o quantity_n of_o a_o drachm_n 7._o it_o cause_v dryness_n of_o the_o mouth_n and_o thirst_v though_o take_v but_o in_o the_o quantity_n of_o 3_o grain_n which_o nothing_o do_v but_o hot_a thing_n 8._o it_o discuss_n and_o all_o discusser_n be_v hot_a for_o it_o be_v by_o heat_n that_o they_o do_v discuss_v as_o spirit_n of_o wine_n cummin-seed_n volatile_a salt_n and_o all_o hot_a spirit_n 9_o it_o soon_o operate_v and_o in_o a_o small_a quantity_n which_o be_v a_o infallible_a proof_n of_o the_o activity_n of_o its_o part_n which_o argue_v heat_n not_o cold._a 10._o it_o cause_v a_o gay_a pleasant_a and_o merry_a humour_n which_o only_a wine_n and_o hot_a liquor_n etc._n etc._n do_v and_o one_o grain_n of_o opium_n will_v cause_v they_o as_o much_o as_o several_a glass_n of_o wine_n which_o argue_v that_o its_o heat_n be_v much_o great_a 11._o i_o will_v fain_o know_v how_o or_o see_v any_o instance_n of_o any_o cold_a thing_n raise_v the_o spirit_n cause_v courage_n magnanimity_n enable_v people_n to_o labour_n journey_n etc._n
be_v repute_v opiate_n borellus_n speak_v of_o a_o soporiferous_a aura_n that_o proceed_v from_o one_o thumb_n cure_v by_o a_o caustick_a i_o have_v read_v of_o a_o cataphora_fw-it from_o worm_n a_o soporiferous_a fume_v from_o the_o womb_n and_o very_o many_o such_o sort_n of_o instance_n which_o thing_n be_v now_o easy_o conceive_v for_o it_o be_v but_o suppose_v a_o fume_v of_o the_o nature_n of_o sem._n animale_a or_o its_o aura_n for_o i_o can_v no_o long_o doubt_v but_o it_o be_v a_o opiate_n and_o it_o will_v have_v much_o the_o same_o effect_n with_o opium_n if_o it_o be_v fit_a to_o use_v it_o after_o the_o same_o manner_n have_v show_v 1._o which_o be_v the_o predominant_a active_a principle_n in_o opium_n and_o how_o combine_v etc._n etc._n 2._o which_o of_o they_o produce_v the_o usual_a and_o laudable_a effect_n of_o opium_n and_o why_o in_o general_a i_o come_v now_o to_o the_o three_o particular_a viz._n to_o show_v iii_o which_o of_o they_o produce_v its_o ill_a effect_n and_o why_o it_o be_v ill_a effect_n be_v these_o viz._n nauseas_fw-la vomit_n which_o be_v general_o very_o dismal_a with_o great_a distress_n and_o sometime_o dangerous_a swim_v in_o the_o head_n hiccough_n distress_n anxiety_n convulsion_n faint_n leipothymy_n syncopes_fw-la etc._n etc._n 1._o note_v that_o its_o grievous_a effect_n be_v at_o or_o about_o the_o region_n of_o the_o stomach_n or_o particular_o the_o mouth_n or_o pit_n thereof_o or_o thence_o arise_v by_o consent_n 2._o note_v that_o see_v there_o be_v nothing_o so_o good_a but_o may_v cause_v evil_a effect_n in_o a_o excessive_a quantity_n this_o enquiry_n be_v more_o proper_o what_o principle_n or_o principle_n of_o opium_n do_v cause_n those_o ill_a effect_n in_o a_o ordinary_a do_v for_o what_o will_v in_o a_o moderate_a do_v will_v be_v sure_a cause_v they_o in_o a_o excessive_a do_v 3._o note_v that_o all_o the_o constant_a effect_n of_o opium_n as_o you_o may_v observe_v in_o the_o enumeration_n thereof_o in_o the_o four_o chapter_n be_v good_a and_o laudable_a effect_n it_o follow_v therefore_o that_o the_o bad_a be_v accidental_a 1._o it_o be_v not_o the_o earthy_a or_o phlegmatic_a part_n of_o opium_n that_o cause_v those_o ill_a effect_n because_o they_o be_v passive_a principle_n and_o consequent_o have_v not_o such_o a_o power_n beside_o that_o they_o be_v know_v to_o be_v innocent_a 2._o opium_n have_v all_o those_o ill_a effect_n when_o both_o the_o earthy_a and_o phlegmatic_a part_n be_v separate_v from_o it_o as_o when_o a_o extract_v of_o well_o torrefy_v opium_n be_v make_v in_o spirit_n of_o wine_n for_o by_o that_o mean_v the_o phlegmatic_a part_n be_v dry_v up_o and_o the_o earthy_a part_n subside_o and_o be_v separate_v yea_o such_o extract_v make_v by_o spirit_n of_o wine_n do_v cause_n those_o evil_a effect_n rather_o more_o than_o crude_a opium_n with_o its_o earth_n and_o phlegm_n in_o it_o as_o experience_n assure_v we_o and_o reason_n will_v plain_o confirm_v by_o and_o by_o however_o fond_a the_o world_n be_v of_o such_o preparation_n 3._o it_o be_v evident_a from_o the_o premise_n that_o the_o sal-volatile-oleosum_a of_o opium_n can_v cause_v those_o vomit_n hiccough_n etc._n etc._n for_o they_o be_v the_o effect_n of_o grievous_a sensation_n at_o stomach_n but_o the_o sal-volatile-oleosum_a cause_n a_o most_o agreeable_a and_o please_a sensation_n at_o stomach_n 4._o nothing_o quiet_v vomit_n convulsion_n â—coughs_n etc._n etc._n more_o than_o that_o sal-volatile-oleosum_a of_o opium_n 5._o experience_n inform_v we_o that_o the_o sal-volatile-oleosum_a of_o opium_n separate_v from_o all_o other_o part_n and_o principle_n thereof_o never_o cause_v such_o evil_a effect_n as_o i_o and_o another_o physician_n in_o london_n can_v testify_v as_o do_v also_o le_fw-fr mort_fw-fr in_o the_o most_o learned_a dr._n love_n collectanea_fw-la where_o he_o say_v of_o such_o a_o preparation_n thereof_o as_o contain_v only_o the_o sal-volatile-oleosum_a that_o nunquam_fw-la anxietates_fw-la circa_fw-la praecordia_fw-la aut_fw-la phantasias_fw-la conciliat_fw-la that_o be_v it_o never_o cause_v anxiety_n about_o the_o mouth_n of_o the_o stomach_n etc._n etc._n for_o that_o be_v most_o proper_o to_o be_v understand_v by_o praecordia_fw-la wedelius_n testify_v the_o like_a of_o such_o another_o preparation_n and_o so_o do_v several_a author_n though_o they_o do_v not_o in_o the_o least_o know_v why_o but_o only_o by_o experience_n 6._o it_o be_v fix_v salt_n be_v innocent_a in_o its_o nature_n and_o but_o the_o 32d_o part_n of_o opium_n which_o be_v too_o inconsiderable_a in_o a_o ordinary_a moderate_a do_v to_o cause_v any_o sensible_a effect_n it_o follow_v therefore_o that_o be_v must_v be_v the_o resinous_n part_n of_o opium_n which_o it_o have_v in_o a_o considerable_a quantity_n that_o must_v cause_v those_o ill_a effect_n this_o manifest_o appear_v 1._o because_o a_o tincture_n of_o opiam_fw-la in_o water_n which_o take_v up_o none_o of_o the_o rosin_n but_o let_v it_o fall_v into_o the_o bottom_n never_o cause_v any_o such_o ill_a effect_n which_o it_o do_v not_o also_o if_o reduce_v to_o a_o extract_v by_o evaporation_n yet_o have_v they_o all_o the_o usual_a good_a effect_n of_o opium_n 2._o wedelius_n in_o his_o opiolog_n assure_v the_o same_o of_o the_o like_a preparation_n in_o phlegm_n of_o distil_a vinegar_n l._n 2._o sect._n 1_o c._n 5._o p._n 92._o 3._o a_o extract_v of_o opium_n in_o spirit_n of_o wine_n do_v often_o cause_v those_o ill_a effect_n and_o no_o other_o preparation_n cause_v they_o as_o often_o wedelius_n ibid._n a_o laudano_n opiato_fw-it cum_fw-la spiritu_fw-la vini_n correcto_fw-la solum_fw-la ferâ—_n observavimus_fw-la ortos_fw-la vomitus_fw-la a_o nostro_fw-la vero_fw-la quod_fw-la cum_fw-la phlegmate_fw-it aceti_fw-la distillati_fw-la fieri_fw-la diximus_fw-la nunquam_fw-la vomitum_fw-la vel_fw-la nauseam_fw-la saltem_fw-la contigisse_fw-la meminimus_fw-la that_o be_v we_o have_v observe_v vomit_n almost_o only_o from_o laudanum_n prepare_v with_o spirit_n of_o wine_n but_o never_o any_o vomit_v or_o nausea_n from_o that_o prepare_v in_o phlegm_n of_o distil_a vinegar_n which_o he_o confirm_v l._n 1._o sect_n 2._o c._n 4._o p._n 62._o saying_n in_o latin_a that_o a_o curious_a observation_n be_v to_o be_v note_v by_o which_o it_o appear_v that_o a_o extract_v of_o opium_n with_o spirit_n of_o wine_n show_v more_o narcotick_a force_n by_o which_o he_o mean_v that_o it_o cause_v more_o ill_a effect_n than_o prepare_v in_o distil_a vinegar_n whereas_o that_o in_o spirit_n of_o wine_n have_v nothing_o more_o in_o it_o than_o that_o in_o vinegar_n beside_o the_o râ—sinous_n part_n therefore_o these_o do_v cause_n all_o the_o mischief_n note_v also_o that_o a_o extract_v in_o spirit_n of_o wine_n have_v in_o it_o quantity_n for_o quantity_n more_o of_o the_o râ—sinous_n part_v than_o crude_a oplum_fw-la both_o because_o the_o earthy_a part_n that_o help_v to_o make_v up_o the_o bulk_n be_v take_v away_o in_o that_o preparation_n and_o because_o the_o 〈◊〉_d of_o wine_n imbibe_v the_o rosin_n more_o greedy_o than_o other_o principle_n of_o the_o opium_n so_o that_o every_o do_v must_v in_o proportion_n have_v much_o more_o rosin_n in_o it_o than_o crude_a opium_n therefore_o it_o be_v no_o wonder_n that_o it_o cause_v those_o ill_a effect_n more_o frequent_o since_o the_o rosin_n be_v most_o certain_o the_o cause_n thereof_o as_o have_v be_v and_o shall_v be_v more_o full_o and_o beyond_o all_o contradiction_n prove_v yet_o be_v this_o the_o preparation_n boast_v of_o by_o the_o blind_a and_o inadvertent_n world_n it_o will_v amaze_v nay_o terrify_v a_o man_n to_o see_v what_o great_a care_n be_v take_v to_o be_v sure_a to_o render_v opium_n mischievous_a by_o solicitous_o use_v spirit_n of_o wine_n in_o extract_a laudanum_n and_o then_o and_o not_o till_o then_o they_o boast_v of_o the_o preparation_n as_o charas_fw-la and_o very_o many_o other_o do_v calling_z it_o not_o without_o great_a ostentation_n and_o desperate_a folly_n their_o laudanum_n may_v it_o be_v they_o and_o none_o other_o a_o turk_n will_v be_v a_o madman_n to_o use_v it_o for_o crude_a opium_n because_o it_o have_v much_o more_o of_o the_o pernicious_a principle_n in_o it_o it_o be_v the_o common_a and_o much_o esteem_v way_n first_o to_o extract_v it_o out_o of_o water_n and_o then_o it_o be_v very_o good_a laudable_a and_o innocent_a but_o think_v nothing_o worth_a till_o they_o extract_v the_o rosin_n that_o be_v all_o leave_v behind_o by_o the_o water_n in_o spirit_n of_o wine_n and_o add_v it_o to_o the_o other_o then_o do_v they_o with_o great_a authority_n praise_v it_o that_o be_v when_o they_o have_v wise_o add_v the_o poison_n to_o the_o panacea_fw-la it_o be_v as_o if_o they_o add_v ratsbane_n to_o a_o cordial_n and_o not_o think_v the_o cordial_a worthy_a commendation_n till_o they_o have_v do_v so_o 4._o it_o appear_v that_o the_o rosin_n be_v
operate_v in_o a_o very_a small_a quantity_n as_o it_o usual_o do_v because_o the_o least_o matter_n imaginable_a affect_v the_o sense_n as_o have_v be_v show_v for_o the_o thousand_o part_n of_o a_o grain_n of_o ambergrise_n musk_n etc._n etc._n affect_v the_o smell_a the_o hundred_o part_n of_o a_o grain_n of_o very_a acrimonious_a thing_n the_o taste_n which_o cause_v very_o sensible_a pleasure_n or_o displeasure_n according_a as_o it_o be_v agreeable_a or_o not_o much_o easy_a may_v the_o exquisite_o dispose_v membrane_n at_o stomach_n which_o be_v affect_v with_o thing_n so_o indefinite_o small_a that_o no_o other_o sense_n or_o membrane_n can_v take_v notice_n of_o as_o the_o particle_n of_o crocus_n metallorum_fw-la in_o vomit_n effluvias_fw-la from_o a_o cat_n body_n pestiferous_a effluvias_fw-la and_o the_o like_a of_o all_o which_o the_o stomach_n be_v so_o sensible_a that_o they_o thereby_o cause_v most_o violent_a symptom_n which_o be_v as_o be_v show_v proportion_v to_o the_o sensation_n therefore_o it_o can_v be_v no_o wonder_n that_o a_o grain_n or_o less_o of_o opium_n shall_v affect_v the_o sensile_a coat_n of_o the_o stomach_n and_o thereby_o cause_v a_o sense_n of_o pleasure_n for_o that_o which_o be_v nice_a to_o discern_v grieve_v particle_n be_v so_o to_o discern_v please_v once_o as_o have_v be_v say_v cujus_fw-la est_fw-la dolour_n ejusdem_fw-la est_fw-la voluptus_fw-la that_o be_v pleasure_n and_o displeasure_n belong_v to_o the_o same_o part_n and_o as_o be_v show_v in_o equal_a degree_n this_o prove_v that_o it_o must_v operate_v by_o pleas_o affect_v the_o stomach_n for_o it_o be_v otherwise_o impossible_a that_o so_o little_a a_o quantity_n shall_v cause_v such_o remarkable_a effect_n and_o that_o before_o the_o opium_n be_v out_o of_o the_o stomach_n but_o it_o be_v ordinary_a for_o the_o stomach_n to_o cause_v mighty_a effect_n by_o its_o sensation_n of_o very_a small_a thing_n otherwise_o insensible_a and_o inconsiderable_a as_o to_o the_o production_n of_o any_o observable_a effect_n and_o therefore_o it_o will_v be_v a_o miracle_n if_o it_o do_v any_o other_o way_n cause_n such_o great_a and_o numerous_a effect_n helmont_n observe_v that_o pro_fw-la remedio_fw-la restaurativo_fw-la archaei_n sive_fw-la animae_fw-la sensitivae_fw-la non_fw-la requiritur_fw-la unciarum_fw-la &_o drachmarum_fw-la quantitas_fw-la sed_fw-la pauca_fw-la grana_n that_o be_v very_o little_a serve_v to_o comfort_v the_o archaeus_n or_o sensitive_a soul_n because_o it_o be_v do_v by_o sensation_n as_o i_o have_v prove_v 2._o it_o be_v as_o evident_a how_o a_o hot_a brisk_a and_o salino-volatile_a thing_n as_o opium_n be_v must_v affect_v the_o sensile_a coat_n of_o the_o stomach_n in_o a_o short_a time_n as_o vomit_n purger_n etc._n etc._n do_v which_o it_o do_v much_o in_o the_o same_o time_n with_o those_o thing_n that_o be_v as_o soon_o as_o they_o insinuate_v themselves_o through_o the_o crusta_fw-la carnosa_fw-la of_o the_o stomach_n and_o reach_v its_o sensile_a coat_n which_o be_v the_o reason_n that_o opium_n vomit_n purger_n etc._n etc._n make_v some_o and_o like_o delay_n before_o they_o operate_v which_o be_v also_o a_o proof_n that_o all_o of_o they_o operate_v by_o affect_v the_o sensile_a coat_n of_o the_o stomach_n all_o the_o difference_n be_v that_o one_o affect_v pleasant_o as_o wine_n meat_n and_o cordial_n and_o the_o other_o by_o a_o grievous_a sensation_n the_o explication_n of_o the_o constant_a effect_n of_o opium_n use_v internal_o etc._n etc._n 1._o the_o first_o and_o lead_v effect_n of_o opium_n be_v cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n this_o be_v a_o property_n that_o belong_v to_o it_o omni_n &_o semper_fw-la and_o indeed_o soli_fw-la to_o opiate_n if_o the_o degree_n duration_n and_o fineness_n of_o the_o pleasure_n be_v consider_v how_o manifest_a be_v it_o from_o what_o have_v be_v say_v of_o the_o most_o complete_a and_o consummate_v sal-volatile-oleosum_a of_o opium_n which_o exact_o agree_v in_o principle_n etc._n etc._n with_o semen_n animale_a that_o so_o high_o please_v and_o titillate_n the_o membrane_n with_o which_o it_o not_o only_o agree_v in_o principle_n as_o be_v show_v but_o have_v they_o more_o active_a actuate_a and_o titillate_v than_o any_o membrane_n that_o it_o must_v of_o necessity_n high_o please_v all_o membrane_n more_o especial_o such_o as_o be_v most_o exquisite_o dispose_v for_o sensation_n as_o the_o most_o sensile_a membrane_n at_o stomach_n be_v not_o only_o by_o its_o agreeableness_n but_o by_o a_o most_o charm_a and_o captivate_a titillation_n that_o actuate_v and_o cause_v a_o fine_a ovation_n and_o serene_a glow_a of_o the_o spiritus_fw-la insiti_fw-la of_o the_o stomach_n which_o make_v it_o please_v in_o the_o high_a manner_n have_v all_o the_o requisite_n to_o cause_n a_o sense_n of_o pleasure_n and_o that_o be_v not_o all_o but_o it_o be_v take_v into_o the_o body_n it_o cause_v a_o long_a continue_a and_o permanent_a sense_n of_o pleasure_n which_o we_o must_v necessary_o carry_v along_o with_o we_o as_o a_o vade_fw-la mecum_fw-la even_o sleep_v or_o wake_v rest_a or_o move_a or_o whatever_o we_o do_v or_o wherever_o we_o be_v by_o which_o mean_n it_o far_o excel_v all_o other_o pleasure_n and_o consequent_o produce_v such_o mighty_a effect_n all_o other_o pleasure_n be_v momentary_a transitory_a desultory_n or_o interrupt_v except_o that_o of_o wine_n and_o cordial_n at_o stomach_n which_o therefore_o have_v the_o like_a effect_n to_o that_o of_o opium_n though_o they_o do_v not_o equal_v it_o in_o the_o intenseness_n or_o duration_n of_o the_o pleasure_n unless_o they_o be_v repeat_v as_o indeed_o they_o may_v be_v which_o make_v i_o to_o intimate_v that_o drink_v a_o good_a glass_n of_o wine_n every_o hour_n and_o by_o that_o mean_n keep_v the_o fresh_a pleasure_n thereof_o continual_o at_o the_o stomach_n like_o that_o of_o opium_n be_v the_o best_a way_n to_o cause_v a_o long_a euphory_n of_o labour_n journey_n etc._n etc._n which_o may_v come_v near_o the_o performance_n of_o our_o divine_a sal-volatile-oleosum_a of_o opium_n though_o never_o equal_v it_o for_o reason_n already_o sufficient_o hint_v viz._n because_o wine_n want_v its_o most_o agreeable_a composition_n and_o fine_a titillation_n of_o the_o volatile_a salt_n that_o opium_n and_o animal_n seed_n have_v note_v that_o the_o pleasure_n of_o opium_n may_v to_o some_o inadvertent_n person_n seem_v very_o indefinite_a though_o it_o be_v at_o stomach_n as_o it_o must_v be_v because_o the_o pleasure_n immediate_o relax_v all_o part_n and_o gratify_v the_o sensitive_a soul_n which_o inform_v the_o whole_a seem_v to_o be_v general_a though_o original_o only_a at_o stomach_n 2._o our_o consummate_v sal-volatile-oleosum_a must_v cause_v a_o blithe_a gay_a and_o good_a humour_n for_o be_v please_v with_o any_o thing_n as_o be_v the_o vulgar_a observation_n cause_v a_o good_a humour_n how_o much_o more_o must_v such_o a_o intense_a agreeable_a and_o continual_a pleasure_n that_o we_o always_o and_o every_o where_o carry_v along_o with_o we_o so_o do_v how_o common_a a_o say_v be_v it_o he_o be_v please_v with_o somewhat_o for_o i_o find_v he_o in_o a_o good_a humour_n 3._o the_o like_a be_v to_o be_v say_v of_o its_o cause_v promptitude_n serenity_n alacrity_n and_o expediteness_n in_o dispatch_v and_o manage_n of_o business_n for_o these_o be_v but_o natural_a and_o necessary_a consequence_n of_o a_o blithe_a gay_a and_o good_a humour_n and_o therefore_o always_o go_v together_o for_o the_o sensitive_a soul_n be_v put_v in_o a_o fine_a ovation_n by_o the_o continual_a pleasure_n be_v more_o active_a and_o have_v thereupon_o as_o be_v show_v whole_o excuse_v himself_o from_o the_o care_n and_o solicitude_n of_o the_o defensive_a contraction_n and_o in_o great_a measure_n of_o the_o vigilative_a contraction_n also_o be_v more_o at_o leisure_n to_o attend_v the_o managery_n of_o other_o affair_n without_o distraction_n beside_o that_o he_o be_v actuate_v and_o enliven_v by_o the_o aforesaid_a ovation_n of_o the_o spirit_n and_o please_a titillation_n into_o a_o alacrity_n and_o promptitude_n for_o any_o business_n with_o which_o also_o he_o be_v less_o tire_v because_o he_o have_v as_o be_v say_v rid_v himself_o of_o the_o fatigue_n of_o the_o contraction_n that_o as_o be_v manifest_o prove_v do_v cause_n lassitude_n which_o otherwise_o can_v hardly_o touch_v or_o affect_v he_o at_o all_o in_o the_o state_n of_o relaxation_n 4._o it_o must_v cause_v assurance_n ovation_n of_o the_o spirit_n courage_n magnanimity_n as_o wine_n do_v by_o elevate_n the_o sensitive_a soul_n by_o pleasure_n and_o a_o high_a titillation_n of_o the_o spiritus_fw-la insiti_fw-la by_o its_o volatile_a part_n actuate_a they_o as_o the_o animal_n semen_n do_v all_o creature_n in_o time_n of_o copulation_n though_o it_o immediate_o affect_v only_o the_o venereal_a membrane_n but_o we_o do_v actuate_v they_o not_o
part_n by_o its_o relax_v the_o pore_n of_o the_o kidney_n and_o render_v the_o humour_n more_o penetrate_v in_o some_o measure_n by_o the_o volatile_a salt_n 20._o it_o cause_v a_o nausea_n by_o its_o rosin_n stick_v to_o and_o teaze_v the_o sensile_a coat_n of_o the_o stomach_n the_o reason_n why_o it_o be_v general_o so_o long_o before_o it_o cause_v a_o nausea_n or_o vomit_v be_v that_o its_o pleasure_n do_v at_o first_o prevent_v it_o till_o at_o last_o the_o stick_a rosin_n urge_v it_o by_o its_o long_a stay_n and_o vexatious_a adherence_n 21._o it_o cause_v swimmings_n in_o the_o head_n by_o consent_n when_o the_o stomach_n be_v grieve_v by_o that_o rosin_n as_o you_o find_v upon_o nauseas_fw-la before_o vomit_v or_o when_o any_o thing_n do_v much_o offend_v the_o stomach_n as_o much_o drink_n or_o wine_n which_o when_o they_o have_v vomit_v those_o swimming_n cease_v 22._o it_o cause_v watch_v in_o some_o person_n who_o be_v of_o very_o movable_a spirit_n by_o actuate_a and_o stir_v their_o spirit_n by_o its_o active_a volatile_a salt_n though_o it_o do_v at_o the_o same_o time_n please_v the_o membrane_n and_o consequent_o relax_v the_o sensile_a part_n and_o thereby_o cause_n indolence_n the_o effect_n of_o relaxation_n which_o it_o also_o do_v when_o people_n keep_v themselves_o from_o sleep_n by_o voluntary_a motion_n and_o therefore_o take_v away_o pain_n even_o when_o man_n travel_v etc._n etc._n beside_o there_o be_v some_o sort_n of_o person_n that_o upon_o joy_n good_a news_n pleasure_n or_o the_o like_a be_v too_o much_o elevate_v or_o have_v a_o restless_a ovation_n of_o the_o spirit_n which_o will_v not_o suffer_v they_o to_o sleep_n though_o they_o be_v in_o a_o pleasant_a condition_n all_o the_o time_n this_o may_v be_v the_o case_n of_o some_o that_o can_v sleep_v after_o opium_n though_o they_o be_v all_o the_o time_n as_o they_o call_v it_o in_o a_o heavenly_a condition_n for_o as_o i_o have_v say_v a_o quietness_n of_o the_o spirit_n be_v requisite_a to_o cause_v sleep_n as_o well_o as_o relaxation_n but_o relaxation_n alone_o and_o thereby_o expansion_n of_o the_o spirit_n so_o that_o they_o can_v carry_v impression_n smart_o be_v sufficient_a to_o cause_v indolence_n and_o the_o pleasure_n to_o cause_v a_o heavenly_a or_o very_o pleasant_a condition_n sanctor_n stat._n med._n sect._n 7._o aph._n 28._o say_v that_o laetitia_n perseverans_fw-la per_fw-la multos_fw-la dies_fw-la somnum_fw-la impedit_fw-la persevere_v pleasure_n may_v do_v the_o same_o by_o like_a reason_n that_o be_v too_o much_o 〈◊〉_d or_o ovation_n of_o the_o spirit_n sometime_o too_o large_a a_o do_v cause_n watch_v by_o over-actuating_a and_o exciting_a the_o spirit_n medicum_fw-la vini_fw-la generosi_fw-la &_o allium_fw-la say_v sanctorius_n conciliant_fw-la somnum_fw-la &_o perspirationem_fw-la si_fw-la vero_fw-la plus_fw-la justo_fw-la sumantur_fw-la utrumque_fw-la prohibent_fw-la perspirabile_fw-la tamen_fw-la in_o sudorem_fw-la convertunt_fw-la that_o be_v a_o little_a generous_a wine_n and_o garlic_n will_v cause_v sleep_n and_o perspiration_n but_o too_o much_o hinder_v both_o yet_o they_o convert_v the_o perspirable_a matter_n to_o a_o sweat_n which_o wine_n and_o garlick_n have_v the_o nature_n of_o opiate_n and_o the_o reason_n why_o they_o sweat_v be_v the_o quantity_n of_o the_o wine_n afford_v more_o moisture_n hypocrates_n say_v 23._o a_o dubious_a state_n between_o sleep_v and_o wake_v be_v cause_v when_o the_o relaxation_n upon_o the_o pleasure_n of_o opium_n incline_v to_o sleep_v but_o the_o irreâ—uiete_a ovation_n of_o the_o spirit_n by_o the_o pleasure_n and_o titillation_n will_v hardly_o suffer_v it_o yet_o high_o please_v and_o put_v they_o in_o a_o sweet_a agreeable_a condition_n chap._n xix_o the_o explication_n of_o the_o rare_a effect_n of_o opium_n in_o a_o moderate_a do_v 1._o it_o cause_v temporary_a pulse_n of_o the_o 〈◊〉_d and_o sometime_o of_o other_o part_n by_o its_o over_o relax_v the_o part_n and_o cause_v thereby_o a_o expansion_n of_o the_o elastic_a spirit_n which_o as_o be_v demonstrate_v weaken_v their_o motion_n 2._o falter_v of_o the_o tongue_n do_v as_o in_o relaxation_n by_o drunkenness_n proceed_v from_o the_o same_o cause_n 3._o looseness_n of_o the_o low_a jaw_n as_o you_o see_v in_o the_o drowsy_a and_o drunken_a people_n be_v from_o the_o same_o relaxation_n 4._o it_o sometime_o prevent_v sweat_n by_o cause_v a_o very_a liberal_a perspiration_n as_o be_v show_v for_o as_o sanctorius_n say_v who_o shall_v know_v it_o much_o insensible_a perspiration_n and_o sweat_n can_v consist_v especial_o in_o a_o temperate_a person_n who_o eat_v and_o drink_v moderate_o therefore_o if_o you_o keep_v a_o person_n that_o sweat_v much_o at_o night_n in_o a_o free_a perspiration_n all_o day_n by_o the_o help_n of_o a_o opiate_n you_o will_v much_o lessen_v or_o total_o prevent_v the_o sweat_n at_o night_n as_o in_o consumptive_a person_n etc._n etc._n 5._o it_o cause_v abortion_n by_o relax_v the_o neck_n of_o the_o womb_n which_o also_o the_o pleasure_n of_o coition_n sometime_o do_v for_o the_o like_a reason_n and_o will_v be_v much_o more_o apt_a to_o cause_v it_o if_o it_o continue_v long_o as_o that_o of_o opium_n do_v note_v the_o inconvenience_n of_o coition_n after_o impregnation_n this_o be_v the_o great_a cause_n that_o whore_n be_v not_o apt_a to_o bear_v child_n because_o frequency_n of_o pleasure_n do_v over-relax_a the_o collum_n 〈◊〉_d 6._o it_o prevent_v abortion_n when_o fear_n terror_n or_o any_o contract_a cause_n as_o grief_n grievous_a passion_n or_o sensation_n do_v threaten_v it_o by_o its_o take_n off_o the_o contraction_n and_o grievance_n that_o cause_v it_o 7_o intumescence_n of_o the_o lip_n be_v from_o their_o relaxation_n admit_v the_o blood_n and_o humour_n into_o they_o in_o a_o plentiful_a manner_n beside_o that_o their_o laxity_n and_o the_o inadvertency_n occasion_v by_o the_o divert_v pleasure_n or_o drowsiness_n that_o follow_v let_v the_o low_a lip_n hang_v down_o careless_o as_o be_v usual_a in_o such_o case_n may_v by_o expose_v much_o more_o of_o that_o lip_n which_o be_v most_o concern_v in_o this_o effect_n make_v it_o seem_v large_a as_o a_o hang_a lip_n do_v 8._o it_o may_v cure_v a_o dropsy_n as_o dr._n wâ—llis_n do_v instance_n 1._o by_o cause_v a_o free_a perspiration_n which_o be_v much_o want_v in_o those_o case_n 2._o by_o relax_v the_o pore_n and_o make_v way_n for_o the_o humour_n to_o 〈◊〉_d 3._o by_o cause_v much_o urine_n as_o cantharides_n millepedes_n &c_n &c_n do_v upon_o the_o account_n of_o their_o volatile-salt_n with_o which_o opium_n abound_v 9_o it_o cure_v stupor_n that_o proceed_v from_o contraction_n as_o by_o cold_a etc._n etc._n by_o relax_v all_o part_n 10._o it_o cause_v anxiety_n and_o distress_n by_o the_o rosin_n stick_v and_o teaze_v the_o stomach_n 11._o vomit_n and_o hiccough_n proceed_v from_o the_o same_o cause_n 12._o convulsion_n be_v cause_v by_o the_o same_o rosin_n while_o it_o continual_o urge_v the_o stomach_n to_o grievous_a vomit_n which_o at_o last_o draw_v other_o part_n as_o the_o stomach_n usual_o do_v when_o under_o great_a grievance_n into_o violent_a contraction_n or_o convulsion_n by_o consent_n to_o endeavour_v its_o assistance_n because_o the_o defensive_a contraction_n grow_v very_o high_a by_o the_o almost_o intolerable_a and_o tedious_a grievance_n at_o stomach_n cause_v a_o mighty_a compression_n of_o the_o springy_a animal_n spirit_n by_o which_o mean_v they_o grow_v very_o forcible_a irrequiete_a and_o violent_o springy_a under_o the_o urgency_n of_o a_o enormous_a compressure_n which_o cause_v such_o convulsive_a motion_n note_v that_o such_o a_o violent_a compression_n of_o the_o animal_n spirit_n into_o a_o great_a springiness_n be_v the_o cause_n of_o the_o strength_n of_o convulsive_a motion_n so_o that_o sometime_o a_o strong_a man_n can_v hardly_o hold_v a_o child_n limb_n in_o such_o case_n 13._o syncopes_fw-la leipothymy_n and_o faint_n follow_v when_o the_o sensitive_a soul_n be_v quite_o tire_v and_o overbear_v by_o the_o fatigue_n of_o such_o distress_n vomit_n and_o defensive_a contraction_n to_o reject_v and_o excuss_v the_o say_v adhere_v and_o teaze_v rosin_n yield_v itself_o to_o rest_n and_o let_v we_o go_v the_o reign_v of_o contraction_n as_o be_v fruitless_a and_o no_o long_o endurable_a whereupon_o all_o the_o sensile_a part_n be_v relax_v in_o the_o high_a degree_n they_o thereby_o grow_v unfit_a for_o sensation_n and_o the_o animal_n spirit_n expand_v as_o far_o as_o the_o atmospherical_a compressure_n permit_v they_o so_o that_o they_o grow_v incapable_a to_o convey_v impression_n by_o which_o mean_v sense_n fail_v and_o motion_n also_o for_o the_o same_o reason_n because_o the_o animal_n spirit_n loose_v their_o springy_a endeavour_n for_o want_n of_o a_o sufficient_a compression_n to_o render_v they_o flippant_a for_o the_o purpose_n which_o be_v the_o cause_n as_o in_o sleep_n that_o sense_n
to_o disparage_v the_o performance_n as_o mean_v and_o obvious_a like_o that_o of_o the_o circulation_n of_o the_o blood_n or_o america_n when_o find_v out_o do_v not_o the_o newness_n of_o the_o thing_n the_o baffle_a endeavour_n of_o all_o mankind_n and_o the_o seem_a impossibility_n of_o ever_o find_v it_o out_o which_o be_v almost_o agree_v upon_o speak_v in_o its_o behalf_n consider_v that_o nothing_o can_v be_v plain_a and_o easy_a but_o what_o be_v true_a and_o consequent_o nothing_o valuable_a but_o what_o be_v so_o what_o be_v true_a knowledge_n but_o the_o knowledge_n of_o thing_n as_o they_o real_o be_v and_o when_o a_o thing_n be_v know_v as_o real_o as_o it_o be_v it_o must_v be_v plain_a and_o never_o so_o till_o then_o for_o to_o take_v a_o thing_n to_o be_v what_o it_o be_v not_o be_v all_o darkness_n error_n puzzle_n confusion_n and_o vanity_n as_o all_o discourse_n of_o opium_n have_v hitherto_o be_v it_o be_v no_o wonder_n then_o that_o the_o cause_n of_o the_o operation_n of_o opium_n grow_v more_o and_o more_o obscure_a while_o they_o state_v the_o cold_a quality_n of_o very_a hot_a opium_n the_o belch_a up_o of_o vulcano_n of_o fume_n from_o the_o stomach_n to_o the_o head_n which_o have_v no_o existence_n their_o act_n as_o a_o poison_n of_o the_o animal_n spirit_n their_o fix_v and_o coagulate_v they_o their_o clog_a they_o by_o adherence_n or_o cloud_v they_o their_o wedge_a themselves_o among_o the_o animal_n spirit_n none_o know_v how_o and_o thereby_o disable_n they_o their_o stuff_v the_o pore_n of_o the_o brain_n or_o compress_v it_o and_o thereby_o hinder_v the_o generation_n of_o animal_n spirit_n to_o be_v the_o cause_n of_o the_o noble_a and_o pleasant_a operation_n of_o opium_n without_o any_o foundation_n in_o nature_n or_o the_o least_o evidence_n of_o sense_n or_o reason_n but_o vain_a fantastical_a imagination_n form_v in_o the_o chimera-forges_a of_o their_o wanton_a brain_n while_o they_o endeavour_v right_o or_o wrong_n to_o appear_v considerable_a folk_n by_o do_v nothing_o to_o the_o purpose_n in_o a_o kind_n of_o pretty_a plausible_a and_o impose_v manner_n thereby_o stuff_v the_o unwary_a world_n with_o wrong_n and_o vain_a conception_n and_o impertinent_a prejudices_fw-la which_o be_v the_o great_a obstacle_n of_o knowledge_n i_o will_v fain_o know_v which_o of_o those_o hypothesise_n can_v tolerable_o solve_v 1_o in_o 10_o of_o the_o phenomena_n that_o i_o have_v enumerate_v or_o indeed_o any_o one_o phenomenon_n true_o mechanical_o and_o demonstrative_o yet_o be_v those_o whim_n the_o glorious_a production_n of_o thousand_o of_o year_n study_n and_o solicitous_a disquisition_n though_o every_o one_o that_o take_v opium_n actual_o feel_v the_o true_a cause_n of_o its_o operation_n viz._n the_o please_a delight_n that_o it_o occasion_v by_o affect_v the_o membrane_n and_o animal_n spirit_n after_o the_o manner_n that_o i_o have_v at_o large_a set_v forth_o good_a god_n what_o blund'r_a groper_n be_v mankind_n who_o daily_o feel_v the_o cause_n it_o never_o can_v find_v though_o thousand_o seek_v it_o with_o a_o eager_a mind_n chap._n xxiv_o of_o opium_n separate_v from_o its_o noxious_a part_n or_o rosin_n and_o whether_o it_o be_v a_o panacea_fw-la etc._n etc._n thus_o far_o have_v i_o speak_v of_o crude_a opium_n joint_o with_o its_o rosin_n or_o noxious_a part_n now_o i_o will_v consider_v it_o separate_v from_o it_o and_o show_v how_o to_o do_v it_o galen_n say_v that_o it_o be_v very_o difficult_a to_o find_v a_o excellent_a remedy_n without_o a_o noxious_a quality_n and_o it_o be_v as_o difficult_a to_o find_v any_o thing_n so_o noxious_a as_o not_o to_o afford_v a_o good_a medicament_n which_o you_o see_v in_o viper_n scorpion_n mercury_n etc._n etc._n all_o or_o most_o physician_n unanimous_o agree_v that_o opium_n have_v such_o a_o noxious_a quality_n that_o cause_v vomit_n hiccough_n distress_n anxiety_n convulsion_n chief_o at_o or_o about_o the_o region_n of_o the_o stomach_n and_o that_o if_o it_o be_v free_v from_o it_o it_o will_v be_v the_o noble_a of_o medicament_n who_o can_v otherwise_o imagine_v see_v it_o be_v so_o excellent_a and_o universal_a a_o remedy_n as_o it_o be_v now_o use_v in_o the_o world_n without_o such_o a_o excellent_a preparation_n thereof_o wherein_o the_o noxious_a principle_n be_v separate_v from_o it_o of_o which_o paracelsus_n say_v that_o whoever_o shall_v enjoy_v it_o will_v be_v a_o professor_n of_o no_o less_o knowledge_n than_o apollo_n machaon_n or_o podalyrius_n though_o he_o be_v the_o great_a master_n of_o arcanas_fw-la panaceas_fw-la etc._n etc._n yet_o do_v he_o confess_v that_o a_o preparation_n of_o opium_n stand_v he_o in_o stead_n and_o perform_v his_o business_n when_o all_o his_o great_a medicament_n fail_v he_o and_o that_o it_o will_v dissolve_v disease_n as_o fire_n doeâ—_n snow_n or_o use_v word_n to_o the_o same_o effect_n helmont_n be_v in_o a_o kind_n of_o rapture_n upon_o consideration_n of_o its_o excellency_n burst_v out_o into_o this_o exclamation_n happy_a be_v the_o sick_a man_n who_o physician_n know_v how_o to_o separate_v the_o deadly_a or_o noxious_a part_v from_o opium_n platerus_n affirm_v that_o he_o can_v with_o a_o preparation_n of_o opium_n preserve_v the_o break_a wheel_n of_o life_n etmuller_n say_v that_o opium_n may_v 〈◊〉_d be_v esteem_v a_o general_a remedy_n and_o the_o main_a end_n of_o his_o tract_n de_fw-fr paruis_fw-la morborum_fw-la initiis_fw-la be_v to_o show_v how_o volatiles_fw-la more_o especial_o salia-volatilia-oleosa_a as_o that_o of_o opium_n may_v in_o small_a quantity_n alter_v we_o and_o cure_v our_o disease_n it_o be_v endless_a to_o tell_v you_o the_o eulogy_n of_o the_o learned_a concern_v such_o a_o preparation_n of_o opium_n which_o they_o general_a conclude_v to_o be_v a_o most_o noble_a panacea_fw-la therefore_o many_o and_o very_o solicitous_a have_v be_v the_o disquisition_n of_o the_o ingenious_a and_o industrious_a to_o find_v out_o this_o heroic_a generous_a and_o most_o glorious_a medicament_n i_o be_o full_o satisfy_v that_o the_o pure_a sal-volatile-oleosum_a of_o opium_n due_o separate_v from_o its_o noxious_a rosin_n dross_n etc._n etc._n be_v the_o very_a thing_n some_o of_o the_o reason_n that_o convince_v i_o be_v as_o follow_v viz._n 1._o because_o opium_n have_v no_o other_o principle_n in_o it_o that_o signify_v any_o thing_n as_o to_o its_o laudable_a and_o noble_a effect_n but_o its_o sal_fw-la volatile_a oleosum_fw-la as_o have_v be_v show_v 2._o because_o the_o sal_fw-la volatile-oleosum_a of_o opium_n produce_v all_o its_o good_a effect_n 3._o because_o the_o sal-volatile-oleosum_a due_o separate_v from_o its_o rosin_n and_o other_o principle_n produce_v no_o ill_a effect_n in_o a_o moderate_a do_v this_o add_v to_o what_o have_v be_v discourse_v at_o large_a of_o the_o principle_n of_o opium_n be_v i_o think_v sufficient_a to_o satisfy_v any_o man_n that_o the_o sal-volatile-oleosum_a of_o opium_n so_o separate_v be_v the_o great_a panacea_fw-la that_o be_v seek_v for_o however_o because_o we_o be_v upon_o the_o great_a thing_n in_o physic_n as_o may_v be_v well_o infer_v from_o what_o have_v be_v already_o say_v and_o that_o the_o world_n have_v be_v under_o great_a fear_n jealousy_n and_o blindness_n concern_v this_o matter_n and_o the_o use_v of_o opium_n it_o will_v be_v well_o worth_a our_o while_n to_o give_v all_o imaginable_a satisfaction_n in_o this_o case_n therefore_o i_o will_v first_o lay_v down_o all_o the_o requisite_a qualification_n of_o a_o complete_a panacea_fw-la as_o far_o as_o i_o can_v collect_v out_o of_o the_o most_o eminent_a author_n and_o my_o own_o consideration_n thereof_o second_o i_o will_v particular_o inquire_v as_o to_o each_o of_o the_o qualification_n whether_o the_o sal_fw-la volatile-oleosum_a of_o opium_n due_o separate_v from_o every_o other_o principle_n of_o opium_n be_v furnish_v therewith_o three_o i_o will_v show_v you_o how_o due_o to_o separate_v its_o dross_n rosin_n etc._n etc._n so_o as_o to_o leave_v a_o pure_a sincere_a sal-volatile-oleosum_a of_o opium_n for_o use._n the_o requisite_a qualification_n of_o a_o panacea_fw-la be_v these_o viz._n 1._o that_o it_o shall_v high_o please_v our_o sensation_n at_o stomach_n because_o the_o stomach_n be_v contrive_v and_o appoint_v by_o god_n and_o nature_n as_o the_o touchstone_n to_o try_v a_o sentinel_n true_o to_o inform_v and_o a_o critical_a judge_n to_o determine_v what_o be_v or_o be_v not_o agreeable_a to_o our_o nature_n in_o general_a and_o therefore_o as_o have_v be_v show_v endue_v with_o a_o wonderful_a sagacity_n and_o nicety_n of_o sensation_n for_o that_o end_n it_o follow_v then_o that_o a_o panacea_fw-la shall_v be_v very_o please_v and_o agreeable_a to_o the_o stomach_n and_o therefore_o very_o cordial_a 2._o that_o it_o shall_v be_v high_o please_v to_o the_o sensitive_a soul_n which_o be_v the_o principle_n of_o all_o motion_n action_n
best_a part_n of_o opium_n which_o be_v so_o much_o the_o better_a the_o more_o it_o abound_v with_o they_o 9_o if_o it_o yield_v any_o other_o tincture_n than_o red_a it_o be_v not_o right_a and_o the_o dull_a or_o pale_a the_o red_a be_v the_o worse_a or_o weak_a it_o be_v 10._o the_o best_a be_v heavy_a in_o proportion_n to_o its_o bulk_n which_o you_o may_v soon_o experiment_n thus_o weigh_v a_o ounce_n of_o each_o in_o the_o air_n then_o weigh_v they_o just_a as_o they_o be_v in_o the_o brass_n scales_n in_o water_n and_o the_o heavy_a will_n outweigh_v the_o other_o in_o water_n for_o the_o heavy_a any_o thing_n be_v the_o less_o water_n take_v from_o its_o weight_n in_o proportion_n to_o its_o bulk_n this_o be_v a_o infallible_a and_o most_o ready_a way_n to_o know_v the_o weight_n of_o any_o thing_n in_o proportion_n to_o its_o bulk_n note_v that_o my_o discourse_n be_v most_o particular_o concern_v the_o best_a sort_n of_o crude_a turkey_n opium_n that_o be_v the_o best_a that_o we_o have_v in_o common_a use_n and_o that_o its_o effect_n and_o not_o those_o of_o any_o preparation_n thereof_o be_v set_v down_o in_o the_o follow_a chapter_n chap_n iii_o the_o effect_n of_o opium_n use_v external_o opium_n use_v external_o have_v two_o sort_n of_o effect_n upon_o a_o humane_a body_n 1._o as_o a_o opiate_n to_o cause_n sleep_n take_v away_o pain_n etc._n etc._n 2._o as_o a_o alterative_a of_o the_o part_n it_o be_v apply_v to_o i._o as_o a_o opiate_n it_o be_v of_o very_o uncertain_a and_o uneven_a effect_n when_o apply_v external_o for_o sometime_o it_o cause_v sleep_n take_v away_o pain_n but_o it_o often_o fail_v therefore_o it_o be_v general_o much_o better_a safe_a more_o certain_a and_o effectual_a to_o use_v it_o internal_o i_o do_v scarce_o know_v the_o case_n wherein_o it_o be_v better_a to_o use_v it_o external_o than_o internal_o unless_o it_o be_v to_o smell_v to_o in_o some_o case_n but_o of_o these_o thing_n more_o particular_o when_o we_o come_v to_o the_o use_v of_o opium_n in_o cure_v prevent_v or_o paliate_a disease_n for_o here_o we_o only_o lie_v down_o effect_n in_o order_n to_o a_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n to_o which_o its_o internal_a effect_n will_v main_o contribute_v however_o it_o may_v be_v very_o useful_a to_o that_o end_n to_o lay_v down_o its_o alterative_a effect_n for_o thereby_o we_o shall_v in_o good_a measure_n know_v the_o prin_fw-mi ciple_n by_o which_o it_o operate_v ii_o it_o be_v external_a effect_n as_o a_o alterative_a be_v these_o viz._n 1._o it_o incides_fw-la resolve_n and_o discuss_n 2._o it_o relax_n and_o mollify_v 3._o it_o maturate_v and_o suppurate_v 4._o it_o exulcerate_v or_o cause_n blister_n if_o it_o be_v very_o strong_a and_o apply_v to_o person_n of_o a_o fine_a texture_n where_o the_o skin_n be_v tender_a but_o this_o effect_n belong_v more_o proper_o to_o the_o maslack_n or_o true_a 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o drop_n from_o the_o incision_n make_v in_o the_o head_n of_o the_o poppy_n especial_o the_o theban_a which_o afford_v a_o very_a powerful_a juice_n hence_o you_o may_v observe_v that_o the_o more_o it_o exulcerates_n or_o blister_n the_o better_a be_v the_o opium_n &_o vice_fw-la versâ_fw-la 5._o it_o be_v a_o psilotherick_n for_o it_o prevent_v hair_n to_o grow_v and_o cause_v the_o shed_v thereof_o 6._o it_o be_v hurtful_a to_o the_o eye_n and_o ear_n 7._o it_o excite_v itch_n apply_v in_o a_o moderate_a manner_n to_o the_o skin_n 8._o it_o excite_v venery_n apply_v to_o the_o perinaeum_n chap._n iu._n the_o effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o the_o moderate_a do_v in_o ordinary_a use_n to_o produce_v the_o follow_a effect_n be_v from_o one_o to_o three_o grain_n more_o or_o less_o according_a to_o the_o circumstance_n condition_n case_n constitution_n age_n &c_n &c_n of_o the_o person_n who_o take_v it_o 2._o it_o operate_v general_o in_o a_o short_a time_n after_o it_o be_v in_o the_o stomach_n that_o be_v in_o about_o half_a a_o hour_n more_o or_o less_o if_o take_v in_o a_o liquid_a form_n and_o in_o about_o a_o hour_n more_o or_o less_o if_o in_o a_o solid_a form_n drink_v a_o draught_n of_o water_n or_o some_o liquor_n after_o it_o otherwise_o it_o may_v be_v sometime_o near_o a_o hour_n and_o a_o half_a before_o it_o have_v its_o full_a effect_n but_o the_o time_n of_o its_o operation_n have_v a_o considerable_a latitude_n according_a to_o the_o disposition_n of_o the_o stomach_n and_o other_o circumstance_n as_o the_o vehicle_n it_o be_v take_v in_o etc._n etc._n the_o constant_a effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o diffuse_v itself_o in_o a_o kind_n of_o indefinite_a manner_n seizing_z one_o not_o unlike_o the_o gentle_a sweet_a deliquium_fw-la that_o we_o find_v upon_o our_o entrance_n into_o a_o most_o agreeable_a slumber_n which_o upon_o yield_v to_o it_o general_o end_v in_o sleep_n but_o if_o the_o person_n keep_v himself_o in_o action_n discourse_n or_o business_n it_o seem_v especial_o when_o give_v in_o a_o mornning_a after_o a_o moderate_a rest_n at_o night_n like_o a_o most_o delicious_a and_o extraordinary_a refreshment_n of_o the_o spirit_n upon_o very_o good_a news_n or_o any_o other_o great_a cause_n of_o joy_n as_o the_o sight_n of_o a_o dear_o belove_a person_n etc._n etc._n thought_n to_o have_v be_v lose_v at_o sea_n or_o the_o like_a cause_v such_o a_o pleasant_a ovation_n of_o the_o spirit_n serenity_n etc._n etc._n as_o we_o find_v after_o a_o competent_a measure_n of_o generous_a wine_n ad_fw-la hilaritatem_fw-la as_o man_n use_v to_o say_v it_o be_v indeed_o so_o unexpressible_o fine_a and_o sweet_a a_o pleasure_n that_o it_o be_v very_o difficult_a for_o i_o to_o describe_v or_o any_o to_o conceive_v it_o but_o such_o as_o actual_o feel_v it_o for_o it_o be_v as_o if_o a_o good_a genius_n possess_v or_o inform_v a_o man_n therefore_o people_n do_v common_o call_v it_o a_o heavenly_a condition_n as_o if_o no_o worldly_a pleasure_n be_v to_o be_v compare_v with_o it_o helmontianus_fw-la will_v doubtless_o express_v it_o by_o the_o archaeus_n in_o his_o very_a best_a humour_n it_o have_v be_v compare_v not_o without_o good_a cause_n to_o a_o permanent_a gentle_a degree_n of_o that_o pleasure_n which_o modesty_n forbid_v the_o name_n of_o and_o it_o be_v well_o worth_a a_o remark_n that_o both_o be_v pleasure_n of_o the_o same_o sense_n viz._n that_o of_o feel_v for_o it_o can_v be_v a_o pleasure_n of_o any_o other_o sense_n since_o it_o be_v internal_a 2._o it_o cause_v a_o brisk_a gay_a and_o good_a humour_n nor_o do_v i_o doubt_v but_o it_o have_v this_o effect_n upon_o sleep_a person_n as_o far_o as_o their_o condition_n be_v capable_a of_o observe_v it_o for_o you_o shall_v have_v they_o often_o tell_v of_o pleasant_a dream_n after_o it_o when_o they_o remember_v they_o and_o speak_v of_o any_o see_v bauchin_n and_o the_o author_n mention_v below_o under_o the_o four_o effect_n of_o opium_n 3._o it_o cause_v promptitude_n serenity_n alacrity_n and_o expediteness_n in_o dispatch_v and_o manage_n of_o business_n to_o which_o end_n and_o that_o of_o a_o good_a and_o gay_a humour_n which_o be_v near_o of_o kind_n it_o be_v common_o take_v in_o the_o morning_n in_o the_o eastern_a country_n with_o most_o certain_a effect_n the_o truth_n of_o which_o wedelius_n be_v force_v to_o confess_v though_o quite_o contrary_a to_o his_o hypothesis_n of_o opium_n fix_v and_o coagulate_v the_o spirit_n give_v a_o instance_n of_o a_o certain_a serene_a person_n who_o when_o she_o have_v any_o affair_n of_o great_a moment_n to_o dispatch_v do_v beforehand_o take_v opium_n with_o great_a advantage_n for_o she_o thereby_o find_v herself_o every_o way_n better_o dispose_v for_o business_n and_o more_o enable_v to_o bear_v the_o fatigue_n thereof_o which_o be_v the_o substance_n of_o what_o he_o write_v in_o latin_n many_o other_o author_n confirm_v the_o truth_n of_o these_o effect_n but_o above_o all_o the_o constant_a experience_n of_o the_o eastern_a nation_n put_v it_o out_o of_o all_o doubt_n 4._o it_o cause_v assurance_n ovation_n of_o the_o spirit_n courage_n contempt_n of_o danger_n and_o magnanimity_n much_o after_o the_o manner_n that_o generous_a wine_n do_v instead_o of_o which_o the_o turk_n etc._n etc._n use_v opium_n before_o engagement_n desperate_a attack_n etc._n etc._n as_o be_v most_o notorious_a to_o make_v they_o courageous_a which_o it_o certain_o do_v for_o your_o satisfaction_n as_o to_o this_o and_o other_o effect_n of_o opium_n not_o so_o common_o observe_v
with_o we_o for_o reason_n give_v in_o chap._n viii_o see_v bellonius_fw-la l._n 3._o c._n 15._o p._n 179._o erastus_n disp._n de_fw-fr sapor_n p._n 6â—_n georg._n andreae_n itenerar_n ind._n l._n 2._o c._n 9_o p._n 12._o camerar_fw-it oper._n subcis_n l._n 1._o c._n 93._o p._n 437._o erastus_n disp._n de_fw-fr narcot_n oberndorf_n historian_n also_o add_v that_o when_o the_o great_a turk_n make_v a_o considerable_a war_n the_o soldier_n buy_v up_o all_o or_o most_o of_o the_o opium_n which_o may_v be_v worth_a a_o merchant_n observation_n for_o it_o thereupon_o grow_v dear_a and_o be_v much_o cheap_a in_o time_n of_o peace_n 5._o it_o prevent_v and_o take_v away_o grief_n fear_v anxiety_n peevishness_n fretfulness_n etc._n etc._n these_o be_v necessary_a consequence_n of_o the_o former_a effect_n 6._o it_o cause_v euphory_n or_o easy_a undergo_n of_o all_o labour_n journey_n etc._n etc._n and_o that_o far_o beyond_o all_o wine_n and_o hot_a cordial_n or_o spirit_n therefore_o it_o be_v very_o much_o use_v in_o turkey_n and_o the_o eastern_a country_n in_o laborious_a undertake_n great_a journey_n etc._n etc._n which_o man_n perform_v by_o the_o help_n of_o opium_n after_o a_o prodigious_a and_o almost_o incredible_a manner_n but_o the_o matter_n of_o fact_n be_v so_o common_a and_o usual_a that_o there_o be_v no_o place_n of_o doubt_n beside_o that_o some_o who_o try_v it_o among_o we_o have_v find_v it_o so_o 7._o it_o lull_v soothe_v and_o as_o it_o be_v charm_v the_o mind_n with_o satisfaction_n acquiescence_n contentation_n equanimity_n etc._n etc._n how_o shall_v it_o fail_v to_o cause_v these_o effect_n since_o it_o cause_v all_o the_o former_a gay_a pleasant_a and_o brave_a humour_n dr._n willis_n and_o other_o have_v no_o true_a experience_n or_o knowledge_n of_o opium_n imagine_v that_o it_o cause_v courage_n bravery_n equanimity_n etc._n etc._n by_o stupify_a the_o sense_n brain_n etc._n etc._n make_v people_n inadvertent_n dull_a and_o inapprehensive_a which_o be_v a_o great_a mistake_n and_o a_o groundless_a conceit_n for_o it_o be_v a_o most_o certain_a truth_n which_o million_o can_v affirm_v that_o it_o produce_v those_o effect_n by_o a_o ovation_n and_o pleasure_n of_o the_o sensitive_a soul_n and_o spirit_n as_o generous_a wine_n do_v before_o man_n be_v suddle_v or_o overcome_v with_o it_o how_o else_o can_v they_o at_o the_o same_o time_n be_v more_o serene_a and_o apt_a for_o the_o management_n of_o any_o business_n and_o neat_a dispatch_n of_o affair_n as_o it_o be_v most_o certain_a they_o be_v these_o fundamental_a mistake_v about_o opium_n have_v be_v as_o you_o will_v find_v hereafter_o one_o great_a cause_n why_o its_o operation_n have_v puzzle_v and_o quite_o baffle_v all_o enquirer_n 8._o it_o quiet_v allay_v and_o compose_v all_o perturbation_n and_o commotion_n of_o the_o spirit_n or_o sensitive_a soul_n blood_n humour_n etc._n etc._n as_o in_o hysterical_a case_n diary_n fever_n that_o proceed_v from_o passion_n as_o anger_n grief_n terror_n etc._n etc._n from_o violent_a motion_n labour_n heat_v journey_n convulsion_n etc._n etc._n or_o from_o pain_n and_o stop_v bleedings_a that_o proceed_v from_o such_o commotion_n 9_o it_o cause_v a_o relaxation_n of_o all_o the_o sensible_a part_n of_o the_o body_n as_o the_o membranous_a and_o nervous_a this_o be_v notorious_a by_o its_o effect_n as_o cause_v perspiration_n sweat_v relaxation_n of_o sphincter_n vilatation_n of_o the_o pupil_n of_o the_o eye_n relaxation_n of_o the_o cornea_n and_o all_o other_o effect_n of_o relaxation_n as_o you_o will_v find_v more_o particular_o hereafter_o 10._o it_o cause_v indolence_n or_o exemption_n from_o pain_n as_o all_o know_v and_o allow_v and_o that_o when_o sleep_n do_v not_o intervene_v 11._o it_o stop_v moderate_v cure_n or_o paliate_v all_o flux_n except_v those_o by_o the_o pore_n or_o such_o as_o depend_v as_o that_o do_v upon_o relaxation_n as_o when_o sphincter_n be_v weak_a or_o paralytical_a but_o these_o last_o be_v unnatural_a accident_n 12._o it_o mighty_o promote_v insensible_a perspiration_n 13._o it_o prevent_v shivering_n in_o ague-fits_a and_o suchlike_a case_n if_o give_v in_o due_a time_n and_o quantity_n which_o shall_v be_v show_v in_o the_o curative_fw-it part._n 14._o it_o prevent_v and_o cure_v cold_n 15._o it_o cause_v a_o large_a and_o slow_a pulse_n suppose_v no_o accidental_a cause_n to_o the_o contrary_n 16._o it_o cause_v dryness_n in_o the_o mouth_n 17._o it_o have_v most_o effect_n in_o warm_a and_o moist_a wether_n 18._o it_o have_v more_o effect_n upon_o lax_n and_o fine_a textured_a person_n as_o woman_n child_n etc._n etc._n therefore_o woman_n seldom_o use_v it_o in_o turkey_n and_o the_o other_o eastern_a country_n where_o it_o be_v common_o use_v by_o the_o men._n 19_o it_o cause_v a_o efflorescence_n of_o the_o skin_n bar_v accident_n of_o cold_a etc._n etc._n 20._o it_o be_v observe_v by_o all_o that_o it_o main_o affect_v the_o genus_fw-la nervosum_fw-la and_o animal_n spirit_n and_o not_o the_o blood_n and_o humour_n 21._o it_o increase_v seed_n in_o some_o measure_n 22._o it_o cause_v a_o great_a promptitude_n to_o venery_n erection_n etc._n etc._n especial_o if_o the_o do_v be_v large_a than_o ordinary_a which_o i_o will_v have_v man_n believe_v without_o experiment_v it_o not_o that_o i_o fear_v to_o be_v confute_v but_o lest_o any_o shall_v injure_v themselves_o by_o too_o great_a a_o do_v this_o be_v one_o great_a cause_n if_o not_o the_o chief_a why_o the_o infidel_n of_o turkey_n and_o the_o eastern_a nation_n especial_o where_o polygamy_n be_v allow_v as_o among_o the_o turk_n etc._n etc._n use_v opium_n so_o much_o it_o never_o â—ailing_v to_o produce_v this_o effect_n in_o hale_v and_o healthy_a people_n if_o the_o do_v be_v sufficient_a as_o be_v too_o notorious_a in_o all_o or_o most_o country_n from_o greece_n to_o japan_n inclusive_o who_o use_v opium_n for_o that_o end_n but_o as_o to_o the_o truth_n of_o this_o effect_n of_o opium_n not_o only_o author_n and_o all_o the_o people_n of_o those_o eastern_a nation_n but_o several_a merchant_n factor_n and_o traveller_n now_o live_v in_o london_n can_v attest_v that_o it_o be_v use_v for_o that_o purpose_n in_o those_o country_n with_o effect_n yea_o some_o in_o our_o own_o nation_n that_o use_v opium_n in_o large_a dose_n can_v attest_v the_o same_o upon_o experience_n in_o their_o own_o body_n those_o who_o desire_v to_o be_v satisfy_v may_v also_o read_v joh._n jacob_n saar_n his_o itinerar_n ind._n p._n 11._o olearius_n â—tinerar_n persio_fw-la l._n 5._o c._n 15._o &_o 18._o b._n d._n d._n sack_n tom._n 11._o epher_n german_n obs._n 69._o p._n 126._o bauchin_n p._n 450._o cardanus_n scaliger_n nich._n monordei_n fogâ—lius_fw-la de_fw-la turcarum_fw-la nepenthe_n bellonius_fw-la and_o other_o who_o word_n i_o do_v not_o repeat_v partly_o for_o modesty_n partly_o for_o brevity_n sake_n it_o do_v i_o confess_v look_v like_o a_o riddle_n that_o a_o most_o relax_a and_o stupify_a medicament_n which_o take_v away_o much_o of_o the_o sense_n of_o feel_v and_o consequent_o irritation_n to_o venery_n as_o one_o will_v think_v shall_v notwithstanding_o irritate_fw-la thereunto_o cause_n erection_n etc._n etc._n however_o it_o be_v most_o certain_a though_o a_o seem_a contradiction_n of_o which_o sort_n you_o have_v many_o more_o among_o the_o effect_n of_o opium_n usual_a and_o frequent_a though_o not_o constant_a effect_n of_o opium_n use_v internal_o in_o a_o moderate_a do_v 1._o sleep_v which_o be_v so_o far_o from_o be_v a_o constant_a effect_n of_o opium_n that_o it_o will_v in_o i_o and_o many_o other_o person_n prevent_v sleep_v even_o when_o otherwise_o incline_v to_o it_o 2._o pleasant_n dream_n 3._o stop_v of_o vomit_n 4._o still_v the_o hiccough_n 5._o take_v off_o convulsion_n and_o contraction_n 6._o cause_v meat_n to_o stay_v long_o at_o stomach_n 7._o moderation_n and_o prevention_n of_o hunger_n 8._o sweat_n 9_o the_o flow_v of_o the_o menses_fw-la though_o not_o observe_v by_o vulgar_a physician_n 10._o the_o flow_v of_o the_o lochia_n which_o be_v as_o little_o observe_v 11._o void_v of_o the_o stone_n 12._o delivery_n of_o woman_n 13._o deadness_n of_o the_o eye_n as_o you_o see_v in_o drunkenness_n 14._o dilatation_n of_o the_o pupil_n 15._o growth_n of_o the_o breast_n penis_n and_o increase_v of_o milk_n 16._o veneral_a dream_n 17._o nocturnal_a pollution_n 18._o itch_n in_o the_o skin_n 19_o much_o urine_n 20._o nausea_n 21._o swimmings_n in_o the_o head_n 22._o watch_v 23._o a_o kind_n of_o dubious_a state_n between_o sleep_v and_o wake_v 24._o it_o stop_v hemorrhage_n in_o many_o case_n many_o more_o instance_n of_o this_o kind_n may_v be_v give_v of_o its_o frequent_a and_o usual_a effect_n in_o disease_n but_o it_o will_v be_v endless_a and_o needless_a since_o we_o have_v mention_v the_o prime_n general_n and_o fundamental_a effect_n upon_o which_o
a_o very_o long_o and_o lavish_a use_n thereof_o the_o inconvenience_n of_o leave_v off_o the_o use_n of_o opium_n do_v bear_v a_o certain_a proportion_n to_o the_o time_n and_o quantity_n that_o it_o have_v be_v use_v in_o 1._o note_v that_o the_o turk_n do_v drink_v some_o water_n always_o after_o the_o take_n of_o opium_n as_o be_v the_o best_a menstruum_fw-la to_o dissolve_v it_o 2._o note_v that_o it_o be_v usual_a with_o they_o to_o take_v a_o drachm_n in_o the_o morning_n and_o so_o much_o in_o the_o afternoon_n and_o so_o may_v we_o as_o well_o as_o they_o if_o use_v to_o it_o and_o it_o be_v a_o very_a silly_a say_n that_o you_o will_v find_v in_o author_n that_o they_o be_v better_a able_a to_o bear_v it_o because_o of_o the_o climate_n etc._n etc._n whereas_o the_o more_o northern_a person_n be_v better_a able_a to_o take_v it_o than_o the_o southern_a as_o will_v hereafter_o appear_v most_o plain_o i_o be_o tell_v of_o one_o near_o banbury_n that_o take_v two_o ounce_n a_o day_n 3._o note_v that_o among_o the_o effect_n of_o opium_n may_v be_v observe_v many_o seem_a contradiction_n yet_o be_v there_o nothing_o more_o certain_a than_o the_o several_a different_a matter_n of_o fact_n which_o no_o doubt_n have_v be_v a_o great_a cause_n to_o puzzle_v the_o world_n about_o it_o and_o to_o run_v man_n into_o strange_a absurdity_n concern_v its_o operation_n and_o all_o to_o deviate_v so_o far_o from_o the_o truth_n that_o nothing_o in_o nature_n can_v be_v far_o unless_o you_o will_v say_v that_o heat_n cool_v or_o what_o please_v the_o sensitive_a soul_n be_v at_o the_o same_o time_n abhor_v by_o it_o now_o because_o these_o seem_a contradiction_n in_o the_o effect_n of_o opium_n be_v the_o great_a rub_n to_o be_v meet_v with_o and_o that_o the_o reader_n may_v take_v the_o better_a estimate_n of_o the_o undertake_n and_o my_o explication_n of_o its_o effect_n when_o i_o come_v to_o it_o i_o shall_v not_o fear_v to_o enumerate_v they_o distinct_o though_o they_o will_v make_v the_o strange_a catalogue_n of_o riddle_n that_o ever_o be_v see_v trust_v in_o he_o that_o create_v this_o wonderful_a medicament_n that_o he_o will_v enable_v i_o to_o explain_v all_o its_o effect_n the_o seem_a contradiction_n in_o the_o effect_n of_o opium_n 1._o it_o cause_v sleep_v and_o watch_v 2._o it_o cause_n and_o prevent_v sweat_n 3._o it_o relax_n and_o stop_v looseness_n 4._o it_o stop_v flux_n and_o cause_n that_o of_o sweat_n etc._n etc._n 5._o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v by_o that_o sense_n to_o venery_n 6._o it_o cause_v stupidity_n and_o promptitude_n in_o business_n cloudiness_n and_o serenity_n of_o mind_n 7._o it_o excite_v the_o spirit_n and_o quiet_v they_o 8._o it_o be_v very_o hot_a yet_o cool_v in_o fever_n 9_o it_o be_v hot_a and_o bitter_a yet_o lessen_v appetite_n even_o in_o cold_a stomach_n 10._o it_o stop_v and_o promote_v urine_n 11._o it_o relax_n and_o weaken_v yet_o enable_v we_o to_o undergo_v labour_n journey_n etc._n etc._n 12._o it_o cause_n and_o prevent_v abortion_n 13._o it_o stop_v vomit_v above_o all_o thing_n yet_o cause_n most_o violent_a tedious_a and_o dangerous_a vomit_n 14._o it_o stop_v purge_v in_o a_o most_o eminent_a manner_n yet_o sometime_o cause_v it_o 15._o it_o be_v very_o acrimonious_a yet_o as_o all_o say_v obtund_v acrimony_n however_o it_o allay_v pain_n proceed_v from_o acrimony_n 16._o it_o cause_v a_o furious_a madness_n yet_o compose_v the_o spirit_n above_o all_o thing_n 17._o it_o cause_v 〈◊〉_d yet_o sometime_o cure_v they_o as_o willis_n say_v 18._o it_o cause_v palsy_n yet_o have_v i_o know_v it_o to_o cure_v a_o palsy_n 19_o it_o cause_v dryness_n in_o the_o mouth_n yet_o take_v off_o thirst_n in_o fever_n 20._o it_o cure_v and_o cause_v a_o hiccough_n 21._o it_o stanche_n blood_n yet_o cause_v the_o blood_n to_o come_v outward_a as_o appear_v by_o the_o efflorescence_n or_o redness_n of_o the_o skin_n that_o it_o cause_n yet_o move_v the_o menses_fw-la and_o lochia_n 22._o we_o have_v many_o instance_n of_o it_o promote_a and_o hinder_v critical_a motion_n 23._o it_o raise_v very_o weak_a people_n when_o nothing_o beside_o will_v do_v it_o yet_o it_o kill_v other_o weak_a people_n 24._o it_o cause_n and_o cure_n convulsion_n 25._o it_o cause_v relaxation_n and_o contraction_n of_o the_o same_o part_n 26._o it_o relax_n yet_o cause_v rigidity_n tension_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n thus_o have_v i_o fair_o and_o faithful_o lay_v the_o whole_a onus_fw-la of_o the_o operation_n effect_n and_o contradictory_n phenomena_n of_o opium_n upon_o my_o shoulder_n however_o i_o come_v off_o and_o clear_v myself_o of_o the_o intricacy_n maze_n and_o cross_a effect_n thereof_o by_o explain_v they_o which_o none_o upon_o the_o view_n thereof_o will_v think_v possible_a and_o none_o before_o i_o dare_v as_o much_o as_o enumerate_v for_o that_o end_n chap._n vii_o the_o author_n contrive_v a_o compendious_a way_n of_o examine_v all_o opinion_n concern_v the_o operation_n of_o opium_n have_v without_o any_o sly_a or_o sordid_a evasion_n or_o considerable_a omission_n which_o have_v be_v the_o perfidious_a course_n of_o author_n in_o this_o case_n full_o and_o true_o enumerate_v the_o sensible_a and_o certain_a effect_n of_o opium_n in_o humane_a body_n and_o thereby_o empanneled_a a_o just_a jury_n for_o the_o trial_n of_o hypothesise_n which_o must_v be_v judge_v by_o the_o effect_n or_o phenomena_n of_o opium_n i_o will_v now_o proceed_v to_o their_o examination_n but_o because_o it_o will_v be_v endless_a to_o take_v every_o one_o particular_o into_o consideration_n i_o will_v use_v their_o stratagem_n who_o blow_v up_o foundation_n to_o save_v the_o tedious_a peck_v at_o all_o the_o part_n of_o the_o superstructure_n which_o in_o this_o case_n will_v require_v a_o age_n and_o take_v up_o all_o my_o time_n in_o demolish_n they_o which_o may_v be_v better_o employ_v in_o erect_v something_o that_o may_v be_v useful_a i_o have_v consider_v and_o find_v that_o the_o foundation_n in_o which_o all_o author_n both_o ancient_a and_o modern_a agree_v and_o whereupon_o they_o have_v hitherto_o endeavour_v to_o build_v look_v upon_o it_o as_o firm_a and_o warrantable_a in_o all_o age_n be_v this_o viz._n that_o opium_n operate_v by_o diminish_v or_o disable_n the_o spirit_n mean_v the_o animal_n spirit_n the_o ancient_n affirm_v that_o it_o do_v so_o by_o a_o extreme_a cold_a quality_n etc._n etc._n and_o the_o modern_n who_o observe_v it_o to_o act_n while_o it_o be_v at_o stomach_n by_o affect_v the_o brain_n nerve_n animal_n spirit_n etc._n etc._n and_o conclude_v no_o action_n be_v perform_v without_o contact_n infer_v and_o agree_v because_o no_o visible_a passage_n can_v be_v find_v from_o the_o stomach_n to_o the_o head_n that_o it_o must_v of_o absolute_a necessity_n act_v by_o fume_n vapour_n auras_fw-la or_o effluvium_n send_v up_o out_o of_o the_o stomach_n to_o the_o brain_n nerve_n etc._n etc._n so_o that_o all_o the_o remain_a question_n among_o the_o modern_n be_v which_o way_n those_o fume_n or_o vapour_n do_v the_o feat_n all_o allow_v the_o fume_n do_v it_o one_o say_v that_o they_o stuff_v the_o pore_n of_o the_o brain_n and_o so_o hinder_v the_o generation_n of_o animal_n spirit_n a_o second_o that_o they_o constringed_a and_o close_v the_o pore_n together_o thereby_o hinder_v the_o say_a generation_n a_o three_o that_o they_o fix_v and_o coagulate_v the_o animal_n spirit_n as_o wedelius_n and_o other_o a_o four_o that_o they_o cloud_v the_o animal_n spirit_n a_o five_o that_o they_o act_v as_o a_o poison_n as_o willis_n and_o many_o other_o a_o six_o that_o they_o clog_v the_o animal_n spirit_n by_o adhere_v to_o they_o etc._n etc._n not_o know_v nor_o i_o think_v care_v what_o they_o say_v so_o they_o humour_a their_o own_o imagination_n and_o hypothesise_n though_o utter_o incapable_a of_o solve_v the_o effect_n of_o opium_n especial_o be_v most_o constant_a proper_a and_o genuine_a effect_n for_o how_o can_v a_o cold_a quality_n which_o opium_n never_o have_v cause_v a_o gay_a and_o brisk_a humour_n bravery_n magnanimity_n euphory_n in_o labour_n promptitude_n to_o venus_n etc._n etc._n and_o how_o can_v cloud_n of_o vapour_n hinder_v the_o generation_n of_o animal_n spirit_n by_o stuff_v or_o constr_v the_o pore_n of_o the_o brain_n poison_v fix_v coagulate_v clog_a or_o cloud_v the_o animal_n spirit_n cause_v a_o fine_a ovation_n thereof_o a_o gay_a brave_a courageous_a and_o magnanimous_a disposition_n euphory_n promptitude_n to_o venery_n serenity_n expediteness_n in_o management_n etc._n etc._n which_o be_v as_o have_v be_v say_v the_o constant_a and_o proper_a effect_n of_o opium_n nor_o indeed_o be_v any_o of_o those_o author_n so_o foolhardy_a as_o to_o attempt_v it_o
why_o then_o do_v they_o write_v and_o trouble_v the_o world_n to_o peruse_v their_o book_n when_o they_o be_v so_o far_o from_o explain_v the_o property_n of_o opium_n that_o they_o scarce_o ever_o dare_v mention_v they_o nor_o set_v their_o hypothesise_n and_o they_o as_o much_o as_o in_o view_n of_o one_o another_o be_v not_o this_o a_o tacit_n confession_n of_o the_o incompetency_n of_o their_o supposition_n i_o beg_v pardon_n for_o call_v they_o they_o though_o they_o themselves_o do_v for_o i_o can_v offer_v they_o a_o great_a abuse_n than_o lay_v their_o spurious_a and_o lame_a brat_n at_o their_o door_n though_o one_o scarce_o need_v say_v any_o more_o of_o they_o yet_o lest_o i_o be_v think_v presumptuous_a or_o saucy_a for_o so_o much_o as_o offer_v to_o suspect_v the_o general_a foundation_n of_o all_o the_o famous_a author_n that_o ever_o live_v as_o galen_n avicenna_n etc._n etc._n among_o the_o ancient_n etmuller_n willis_n etc._n etc._n among_o the_o modern_n 1._o i_o will_v show_v you_o very_o just_a cause_n to_o suspect_v the_o insufficiency_n of_o the_o general_a foundation_n viz._n that_o opium_n diminish_v or_o disable_v the_o spirit_n 2._o i_o will_v prove_v that_o it_o do_v not_o do_v it_o by_o a_o cold_a quality_n 3._o that_o it_o do_v not_o do_v it_o by_o vapour_n fume_n aura_n or_o any_o such_o way_n 4._o that_o it_o diminish_v or_o disable_v the_o spirit_n by_o no_o mean_n whatsoever_o which_o diminish_v or_o disable_n of_o the_o spirit_n cold_a quality_n and_o fume_n or_o aura_n comprehend_v the_o foundation_n of_o all_o opinion_n concern_v opium_n that_o ever_o i_o read_v or_o hear_v of_o and_o consequent_o if_o those_o two_o fundamental_a opinion_n be_v refute_v all_o the_o superstructure_n that_o have_v be_v in_o this_o case_n must_v fall_v to_o the_o ground_n chap._n viii_o the_o author_n show_v just_a cause_n of_o his_o suspicion_n that_o all_o author_n have_v go_v upon_o a_o wrong_a foundation_n in_o their_o disquisition_n of_o the_o cause_n of_o the_o operation_n of_o opium_n i_o have_v show_v you_o that_o the_o general_a foundation_n of_o both_o ancient_n and_o modern_a author_n be_v that_o opium_n do_v diminish_v or_o disable_v the_o spirit_n and_o now_o i_o will_v plain_o show_v just_a cause_n of_o my_o suspicion_n of_o its_o insufficiency_n which_o be_v these_o 1._o i_o observe_v that_o all_o learned_a man_n be_v to_o this_o day_n high_o dissatisfy_v as_o to_o the_o cause_n and_o manner_n of_o the_o operation_n of_o opium_n notwithstanding_o all_o that_o have_v be_v write_v concern_v it_o and_o that_o it_o be_v the_o common_a cry_n on_o all_o hand_n that_o none_o have_v illustrate_v the_o operation_n of_o opium_n to_o any_o purpose_n or_o give_v any_o satisfaction_n therein_o and_o therefore_o learned_a physician_n be_v still_o as_o much_o upon_o the_o enquiry_n as_o ever_o they_o be_v it_o be_v much_o more_o civil_a and_o reasonable_a to_o suspect_v the_o foundation_n that_o all_o former_a author_n have_v build_v upon_o than_o a_o general_a failure_n in_o all_o the_o most_o judicious_a master_n builder_n that_o ever_o endeavour_v to_o build_v thereon_o for_o if_o all_o the_o best_a architect_n of_o the_o whole_a world_n fail_v to_o erect_v a_o firm_a superstructure_n upon_o any_o one_o foundation_n what_o can_v we_o think_v but_o that_o the_o foundation_n be_v infirm_a especial_o when_o as_o in_o our_o case_n no_o way_n that_o care_n judgement_n perspicacity_n and_o wit_n can_v invent_v or_o think_v of_o have_v be_v leave_v untried_a to_o build_v thereon_o so_o that_o though_o i_o modest_o call_v it_o a_o cause_n of_o suspicion_n it_o amount_v almost_o if_o not_o altogether_o to_o a_o demonstration_n that_o the_o foundation_n that_o all_o author_n have_v go_v upon_o be_v naught_o will_v not_o any_o consider_a man_n when_o he_o see_v all_o the_o judicious_a architect_n of_o the_o world_n fail_v to_o erect_v a_o firm_a building_n upon_o a_o certain_a foandation_n seek_v for_o another_o therefore_o who_o can_v blame_v i_o if_o i_o do_v and_o not_o blame_v they_o that_o do_v not_o the_o mean_a bricklayer_n or_o carpenter_n that_o shall_v be_v guilty_a of_o such_o stupidity_n as_o to_o attempt_v to_o build_v upon_o such_o a_o foundation_n as_o always_o deceive_v the_o builder_n will_v be_v think_v too_o great_a a_o blockhead_n to_o be_v employ_v in_o building_n 2._o i_o observe_v that_o most_o man_n do_v notwithstanding_o that_o foundation_n be_v agree_v upon_o think_v it_o impossible_a to_o explain_v the_o intricate_a various_a contradictory_n phenomena_n and_o mysterious_a effect_n of_o opium_n sit_v content_v and_o persuade_v that_o it_o operate_v by_o a_o occult_a quality_n whole_o unexplicable_a and_o particular_o reserve_v from_o the_o knowledge_n of_o mankind_n but_o nature_n work_v mechanical_o in_o weight_n measure_n etc._n etc._n therefore_o it_o be_v more_o than_o probable_a that_o it_o be_v only_o their_o be_v upon_o a_o wrong_a bottom_n make_v it_o seem_v absolute_o occult_a for_o it_o be_v impossible_a to_o find_v a_o thing_n where_o it_o be_v not_o or_o to_o build_v firm_o upon_o a_o insufficient_a foundation_n whereas_o have_v it_o be_v right_o and_o true_a it_o be_v not_o to_o be_v imagine_v but_o some_o or_o other_o will_v have_v thereupon_o do_v something_o that_o will_v have_v stand_v against_o all_o wind_n and_o storm_n which_o none_o have_v do_v 3._o i_o observe_v that_o none_o dare_v venture_v to_o lay_v the_o whole_a no_o nor_o one_o half_a of_o the_o burden_n of_o the_o phinomena_n or_o effect_n of_o opium_n upon_o that_o foundation_n foresee_v doubtless_o that_o it_o can_v not_o bear_v they_o and_o that_o if_o they_o lay_v any_o more_o weight_n thereon_o the_o whole_a will_v totter_v and_o fall_v to_o the_o ground_n the_o project_n in_o every_o hypothesis_n be_v to_o persuade_v man_n of_o the_o truth_n thereof_o and_o the_o only_a way_n to_o do_v it_o be_v to_o solve_v all_o phenomena_n thereby_o for_o if_o it_o fail_v but_o in_o one_o it_o be_v a_o infallible_a sign_n of_o its_o insufficiency_n there_o be_v no_o reason_n to_o omit_v any_o of_o the_o phenomena_n if_o they_o can_v have_v discern_v that_o the_o hypothesis_n will_v have_v bear_v they_o therefore_o as_o have_v be_v intimate_v it_o imply_v a_o confession_n of_o its_o incompetency_n 4._o i_o observe_v that_o ancient_a author_n write_v of_o opium_n before_o it_o come_v to_o be_v of_o common_a and_o general_a use_n in_o the_o daytime_n with_o healthy_a person_n as_o it_o since_o be_v in_o many_o nation_n to_o cause_v a_o gay_a pleasant_a and_o good_a humour_n take_v off_o sadness_n melancholy_a and_o anxiety_n to_o cause_n assurance_n boldness_n courage_n bravery_n magnanimity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n promptitude_n in_o business_n expediteness_n and_o serenity_n to_o excite_v to_o venery_n etc._n etc._n which_o effect_n can_v be_v explain_v by_o that_o supposition_n of_o disable_n the_o spirit_n and_o that_o they_o use_v opium_n only_a medicinally_n for_o the_o sake_n of_o such_o other_o effect_n as_o may_v be_v tolerable_o well_o explicate_v by_o that_o hypothesis_n so_o that_o they_o have_v not_o any_o occasion_n nor_o inducement_n to_o look_v any_o far_o the_o effect_n they_o give_v it_o for_o be_v only_o 1._o to_o cause_v sleep_n 2._o to_o take_v off_o pain_n 3._o to_o stop_v flux_n 4._o to_o compose_v the_o spirit_n 5._o to_o cause_v perspiration_n and_o sweat_n all_o which_o be_v not_o inconsistent_a with_o the_o hypothesis_n of_o diminish_v or_o disable_n the_o spirit_n as_o the_o other_o be_v and_o therefore_o may_v well_o deceive_v they_o for_o first_o sleep_n be_v cause_v by_o diminish_v the_o spirit_n by_o labour_n watch_v etc._n etc._n as_o be_v most_o notorious_a over_o the_o whole_a world_n so_o other_o thing_n that_o diminish_v the_o spirit_n as_o bleed_v vomit_v purge_v and_o many_o other_o cause_n of_o diminish_v thereof_o do_v incline_v we_o to_o sleep_v second_o indolence_n or_o exemption_n from_o pain_n be_v cause_v by_o nothing_o more_o than_o want_v of_o spirit_n as_o in_o paralytical_a case_n stuporâ—_n obstruction_n or_o compression_n of_o the_o nerve_n syncopes_fw-la leipothymy_n deliquium_n faint_n after_o bleed_v and_o sleep_v which_o as_o be_v say_v be_v so_o much_o cause_v by_o loss_n of_o spirit_n etc._n etc._n three_o flux_n be_v stop_v or_o moderate_v by_o nothing_o better_a than_o sleep_n which_o general_o as_o be_v say_v proceed_v from_o loss_n of_o spirit_n what_o also_o stop_v or_o moderate_v flux_n more_o than_o want_v of_o the_o sense_n of_o the_o irritation_n of_o humour_n and_o what_o take_v away_o sense_n more_o than_o want_v of_o spirit_n thus_o want_v of_o sense_n by_o the_o absence_n of_o the_o spirit_n in_o paralytical_a intestine_n stop_v flux_n thus_o fail_v a_o paralytical_a bladder_n to_o express_v the_o urine_n so_o a_o palsy_n of_o the_o membrane_n
etc._n as_o wine_n hot_a liquor_n and_o opium_n do_v 12._o opium_n do_v very_o much_o open_v the_o pore_n and_o cause_n perspiration_n etc._n etc._n which_o only_a heat_n as_o that_o in_o bath_n bagnio_n hot_a house_n and_o hot_a thing_n do_v but_o cold_a shut_v the_o pore_n as_o all_o know_v therefore_o 13._o opium_n cure_v and_o prevent_v cold_n which_o be_v another_o argument_n of_o its_o heat_n 14._o it_o be_v a_o great_a aphrodisiack_a or_o exciter_n to_o venery_n which_o cold_a thing_n chill_a but_o hot_a thing_n as_o cantharides_n bee_n pismire_n onion_n garlic_n leek_n rocket_n squill_n horse_n radish_n sem._n human._n etc._n etc._n do_v promote_v 15._o nothing_o cause_v indolence_n give_v internal_o but_o wine_n hot_a liquor_n etc._n etc._n as_o i_o can_v think_v of_o and_o opium_n cause_v it_o much_o after_o the_o same_o manner_n as_o wine_n do_v first_o cause_v mirth_n and_o jollity_n and_o upon_o increase_n of_o quantity_n very_o considerable_a indolence_n it_o be_v true_a that_o cold_a will_v external_o cause_v a_o stupor_n if_o it_o be_v intense_a so_o as_o to_o constringe_v the_o part_n and_o exclude_v the_o spirit_n but_o otherwise_o it_o make_v the_o feel_v more_o nice_a as_o all_o know_v by_o experience_n because_o every_o little_a hurt_n affect_v we_o more_o when_o we_o be_v cold_a than_o hot_a but_o this_o be_v not_o the_o case_n of_o relax_a opium_n which_o be_v use_v internal_o to_o take_v away_o pain_n as_o wine_n etc._n etc._n 16._o nothing_o take_v away_o the_o effect_n of_o opium_n or_o drunkeness_n better_o than_o cold_a thing_n internal_o and_o external_o as_o acid_n dip_v in_o cold_a water_n etc._n etc._n 17._o opium_n relax_n all_o part_n which_o heat_n do_v and_o cold_a constringe_n as_o be_v intimate_v 18._o wedelius_n confess_v though_o it_o make_v against_o what_o he_o say_v that_o he_o never_o observe_v a_o soporose_n distemper_n where_o there_o be_v not_o a_o preternatural_a heat_n opiolog_fw-la lib._n 1._o sect._n 1_o cap._n 12._o p._n 46._o 19_o if_o it_o cause_v sleep_n by_o its_o cold_a quality_n than_o all_o thing_n that_o be_v cold_a will_v do_v it_o proportionable_o cucumber_n purslane_n etc._n etc._n will_v be_v so_o great_a hypnotick_n that_o we_o shall_v not_o be_v able_a to_o eat_v a_o drachm_n of_o they_o but_o that_o they_o will_v cause_v a_o great_a sopor_fw-la but_o there_o be_v no_o such_o thing_n and_o hot_a thing_n be_v much_o more_o apt_a to_o cause_v sleep_n or_o a_o sopor_fw-la as_o wine_n hot_a spirit_n onion_n garlic_n and_o such_o like_a 20._o opium_n cause_v a_o redness_n or_o efflorescence_n of_o the_o skin_n make_v it_o sensible_o warm_a as_o heat_n wine_n and_o strong_a liquor_n do_v 21._o it_o cause_v also_o a_o itch_a of_o the_o skin_n which_o only_o hot_a thing_n do_v 22._o half_n a_o drachm_n of_o opium_n in_o clyster_n have_v cause_v a_o violent_a heat_n in_o the_o gut_n 23._o it_o stop_v diarrheas_n or_o looseness_n which_o cold_a cause_n 24._o it_o stop_v defluxion_n cough_n etc._n etc._n which_o cold_a cause_n 25._o to_o pin_v up_o all_o its_o predominant_a principle_n appear_v by_o autopsie_n upon_o its_o chemical_a analysis_n to_o be_v volatile_a salt_n and_o sulphur_n beside_o this_o opinion_n of_o the_o coldness_n of_o opium_n be_v very_o much_o explode_v and_o indeed_o it_o be_v so_o apparent_o false_a and_o absurd_a that_o i_o shall_v not_o have_v think_v it_o worth_a while_n to_o argue_v against_o it_o but_o that_o it_o lay_v so_o in_o my_o way_n that_o regular_o i_o can_v not_o well_o avoid_v it_o without_o breach_n of_o order_n and_o method_n i_o may_v have_v add_v that_o it_o resolve_v attenuate_v etc._n etc._n but_o it_o be_v needless_a to_o say_v any_o more_o it_o be_v very_o false_a and_o erroneous_a that_o it_o stop_v flux_n by_o incrassate_v and_o bind_v which_o be_v account_v cold_a quality_n if_o so_o how_o shall_v it_o stop_v they_o when_o pound_n of_o incrassative_n and_o binder_n have_v fail_v though_o the_o opium_n be_v give_v only_o in_o the_o quantity_n of_o a_o grain_n or_o two_o how_o shall_v it_o stop_v or_o moderate_a flux_n even_o while_o it_o be_v yet_o at_o stomach_n as_o it_o most_o certain_o do_v it_o bear_v as_o etmuller_n well_o observe_v no_o proportion_n to_o the_o blood_n and_o humour_n to_o have_v any_o effect_n that_o may_v be_v remarkable_a upon_o they_o for_o a_o grain_n be_v but_o as_o 1_o to_o 115200_o to_o the_o blood_n of_o he_o that_o have_v 20_o pound_n of_o blood_n which_o a_o ordinary_a man_n have_v beside_o how_o can_v altenuative_n resolver_n and_o discusser_n incrassate_fw-it or_o bind_z but_o more_o especial_o how_o can_v so_o great_a a_o relaxer_n of_o part_n be_v a_o constringer_n thereof_o that_o be_v perfect_a contradiction_n and_o how_o can_v a_o mere_a sal_fw-la volatile_a oleosum_fw-la in_o which_o all_o its_o virtue_n lie_v as_o will_v plain_o appear_v thicken_v and_o bind_v the_o truth_n be_v that_o it_o stop_v flux_n as_o sleep_n do_v by_o take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o solicit_v the_o part_n to_o contract_n and_o so_o to_o extrude_v and_o squeeze_v they_o out_o it_o promote_v perspiration_n by_o relax_v the_o pore_n as_o sleep_n do_v it_o also_o seem_v to_o thicken_v rheum_n as_o sleep_n do_v because_o it_o cause_v sleep_n or_o at_o least_o take_v away_o a_o sense_n of_o the_o irritation_n of_o the_o rheum_n be_v thereby_o suffer_v to_o stay_v till_o it_o thicken_v by_o the_o heat_n of_o the_o body_n the_o irritation_n also_o at_o windpipe_n be_v less_o because_o the_o flux_n of_o the_o rheum_n be_v moderate_v for_o the_o reason_n aforesaid_a but_o of_o these_o thing_n more_o full_o when_o we_o come_v to_o explain_v the_o cause_n or_o cause_n of_o the_o effect_n of_o opium_n chap._n x._o it_o be_v prove_v that_o opium_n send_v no_o fume_n etc._n etc._n from_o the_o stomach_n to_o the_o head_n brain_n etc._n etc._n and_o therefore_o that_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n etc._n etc._n by_o that_o mean_n though_o the_o opinion_n of_o the_o cold_a of_o opium_n be_v much_o explode_v that_o of_o fume_n vapour_n or_o aura_n arise_v from_o the_o opium_n at_o stomach_n and_o mount_v up_o to_o the_o brain_n etc._n etc._n be_v as_o much_o receive_v and_o embrace_v i_o know_v none_o but_o such_o as_o think_v it_o absolute_o necessary_a consider_v that_o it_o be_v most_o certain_a and_o allow_v by_o all_o observe_a man_n that_o opium_n produce_v all_o or_o most_o of_o its_o effect_n while_o it_o be_v at_o stomach_n that_o the_o genus_fw-la neruâ—sum_fw-la be_v most_o concern_v in_o its_o operation_n and_o that_o as_o be_v say_v there_o be_v no_o operation_n or_o action_n but_o by_o contact_n so_o that_o the_o modern_n acquiesce_v in_o the_o necessity_n of_o its_o operate_n that_o way_n because_o they_o can_v conceive_v no_o other_o which_o be_v no_o proof_n but_o a_o defect_n of_o their_o conception_n look_v upon_o it_o as_o invincible_a and_o uncontrollable_a evidence_n oâ—_n its_o operate_n by_o detachment_n of_o fume_n or_o 〈◊〉_d send_v up_o to_o the_o brain_n from_o the_o stomach_n which_o appear_v so_o undeniable_o conclusive_a that_o neither_o the_o want_n of_o a_o sensible_a passage_n nor_o any_o other_o inconvenience_n signify_v any_o thing_n with_o they_o to_o the_o contrary_a therefore_o it_o become_v a_o establish_a foundation_n by_o common_a consent_n only_o they_o differ_v as_o be_v show_v in_o the_o manner_n how_o those_o fume_n produce_v the_o effect_n of_o opium_n and_o well_o they_o may_v see_v there_o be_v no_o such_o thing_n nor_o possibility_n if_o they_o be_v of_o ever_o explicate_v the_o various_a effect_n of_o opium_n by_o that_o mean_n as_o will_v manifest_o appear_v i_o confess_v that_o if_o opium_n operate_v by_o such_o fume_n pass_v from_o the_o stomach_n to_o the_o brain_n etc._n etc._n it_o will_v be_v easy_a to_o conceive_v how_o it_o shall_v diminish_v or_o disable_v nay_o utter_o ruin_v the_o animal_n spirit_n and_o indeed_o impossible_a rational_o to_o conceive_v how_o they_o can_v do_v otherwise_o but_o then_o the_o enliven_a invigorate_n and_o encourage_v effect_n of_o opium_n which_o be_v its_o constant_a and_o most_o genuine_a off_o spring_n will_v lie_v upon_o our_o hand_n without_o any_o possibility_n of_o give_v a_o account_n thereof_o for_o certain_o dull_a heavy_a unnatural_a undigested_a and_o cloudy_a fume_n or_o vapour_n can_v not_o advantage_v the_o animal_n spirit_n cause_v a_o triumph_n or_o ovation_n thereof_o at_o their_o access_n courage_n serenity_n promptitude_n magnanimity_n euphory_n inclination_n to_o venery_n etc._n etc._n which_o we_o be_v most_o oblige_v to_o regard_n as_o be_v its_o most_o natural_a and_o proper_a effect_n this_o opinion_n of_o the_o modern_n do_v presume_v or_o suppose_v for_o they_o prove_v nothing_o first_o that_o fume_n
as_o to_o the_o nose_n and_o eye_n for_o though_o some_o of_o my_o reader_n may_v not_o easy_o conceive_v it_o the_o representation_n of_o thing_n may_v have_v be_v convey_v by_o reflection_n and_o refraction_n of_o light_n without_o exclude_v the_o air_n but_o that_o it_o be_v more_o convenient_a and_o safe_a for_o the_o brain_n and_o optic_a nerve_n which_o be_v much_o the_o same_o matter_n with_o the_o brain_n and_o a_o production_n thereof_o that_o the_o air_n shall_v be_v exclude_v 6._o notwithstanding_o all_o this_o care_n to_o exclude_v extraneous_a particle_n how_o fine_a soever_o we_o do_v find_v that_o those_o very_a impulse_n convey_v by_o the_o animal_n spirit_n themselves_o in_o the_o most_o gentle_a manner_n imaginable_a do_v often_o offend_v the_o brain_n now_o fair_o consider_v the_o great_a excellency_n and_o use_v of_o the_o brain_n viz._n to_o separate_v the_o animal_n spirit_n to_o accommodate_v the_o soul_n with_o a_o fit_a seat_n for_o it_o its_o tenderness_n and_o softness_n to_o be_v next_o to_o liquidity_n how_o careful_o it_o be_v guard_v with_o about_o nine_o or_o ten_o circumvallation_n or_o considerable_a integument_n that_o those_o we_o common_o call_v organ_n of_o sensation_n be_v contrive_v for_o shutter_n out_o or_o excluder_n of_o the_o least_o extraneous_a particle_n effluvia_n or_o aura_n that_o the_o least_o fume_v that_o rise_v from_o any_o part_n and_o arrive_v at_o the_o brain_n cause_v such_o terrible_a and_o dismal_a effect_n and_o that_o most_o gentle_a touch_n of_o the_o animal_n spirit_n do_v offend_v it_o so_o as_o to_o cause_v tragical_a event_n as_o hysterick_a fit_n vertigo_n &c._n &c._n be_v it_o likely_a that_o notwithstanding_o the_o considerableness_n tenderness_n use_v and_o excellency_n of_o the_o brain_n the_o extraordinary_a providence_n use_v in_o guard_v it_o from_o effluvia_n or_o extraneous_a particle_n how_o fine_a soever_o and_o the_o apparent_a mischief_n that_o the_o least_o fume_v nay_o bare_a impulse_n present_v by_o the_o animal_n spirit_n do_v cause_n that_o the_o same_o providence_n that_o so_o guard_v it_o which_o do_v nothing_o in_o vain_a shall_v after_o all_o its_o care_n and_o nice_a circumspection_n to_o exclude_v the_o least_o fume_v etc._n etc._n permit_v and_o free_o let_v loose_v upon_o it_o and_o into_o it_o whole_a and_o even_o continual_a gust_n blast_n and_o vulcano_n of_o acid_n acrimonious_a putrid_a hot_a stink_a corrosive_a fume_n vapour_n and_o steam_n arise_v from_o glut_a debauch_a and_o surfeit_v stomach_n contain_v all_o imaginable_a trash_n hodgepodge_n vermine_n choler_n etc._n etc._n sure_a it_o be_v much_o fit_a quite_o to_o discharge_v and_o rid_v nature_n of_o they_o at_o mouth_n or_o rather_o send_v they_o downward_o with_o their_o fit_a companion_n the_o stink_a ordure_n and_o excrement_n than_o prefer_v they_o to_o the_o high_a and_o noble_a part_n of_o the_o animal_n and_o sacred_a mansion_n of_o the_o soul_n for_o if_o there_o be_v so_o ready_a free_a open_a and_o constant_a a_o passage_n sensible_a or_o insensible_a for_o the_o fume_n of_o opium_n which_o never_o fail_v of_o its_o effect_n then_o certain_o must_v the_o passage_n be_v alike_o free_a to_o all_o other_o fume_n from_o the_o stomach_n see_v they_o be_v so_o to_o those_o gross_a venomous_a and_o pernicious_a fume_n of_o opium_n as_o willis_n and_o most_o of_o the_o modern_a and_o ancient_a physician_n do_v state_n they_o to_o be_v then_o farewell_n soul_n brain_n life_n and_o all_o for_o it_o be_v not_o conceivable_a that_o the_o man_n can_v hold_v out_o one_o houâ—_n under_o such_o horrid_a and_o dismal_a circumstance_n and_o dreadful_a eructation_n of_o rude_a and_o crude_a fume_n who_o can_v not_o bear_v the_o arrival_n of_o the_o least_o vapour_n scarce_o sensible_a in_o quantity_n or_o quality_n arise_v from_o any_o other_o part_n or_o be_v it_o a_o peculiar_a privilege_n that_o the_o stomach_n have_v thus_o to_o send_v fart_n with_o their_o heel_n upward_o as_o belch_a be_v call_v without_o any_o offence_n to_o perfume_v the_o soul_n presence-chamber_n save_v your_o presence_n however_o foh_o for_o shame_n what_o sort_n of_o opinion_n be_v these_o what_o thick_a stink_a and_o dark_a cloud_n scotomy_n and_o stupor_n must_v the_o opiniator_n be_v under_o by_o their_o own_o consent_n 7._o if_o this_o be_v the_o case_n no_o part_n in_o the_o whole_a body_n will_v be_v in_o such_o a_o miserable_a state_n as_o the_o chief_a for_o the_o rectum_fw-la or_o colon_n be_v fit_v and_o fortify_v by_o nature_n to_o bear_v such_o thing_n so_o be_v not_o the_o tender_a brain_n 8._o what_o horse_n brain_n much_o less_o humane_a one_o can_v bear_v incessant_a raking_n penetration_n stuff_n of_o such_o unnatural_a indigested_a heterogeneous_a rugged_a acid_a acrimonious_a putrid_a and_o impetuous_a fume_n if_o gutta_n cavat_fw-la lapidem_fw-la non_fw-la vi_fw-la sed_fw-la saepe_fw-la cadendo_fw-la what_o will_v become_v of_o the_o tender_a brain_n thus_o â—udely_o rub_v and_o grate_v all_o the_o day_n of_o our_o life_n if_o it_o can_v hold_v out_o any_o for_o it_o be_v incredible_a it_o shall_v 9_o how_o will_v the_o pore_n of_o that_o soft_a substance_n which_o have_v no_o less_o office_n as_o it_o be_v universal_o receive_v than_o to_o separate_v animal_n spirit_n which_o be_v or_o shall_v be_v the_o fine_a and_o most_o subtle_a tenuious_a and_o principal_a thing_n in_o a_o animal_n next_o the_o soul_n itself_o be_v discompose_v tear_v dilate_a stuff_v what_o a_o bless_a sâ—retion_n of_o animal_n spirit_n if_o any_o will_v there_o be_v 10._o it_o be_v observe_v by_o all_o that_o the_o brain_n though_o very_o soft_a receive_v the_o least_o change_n of_o any_o part_n of_o the_o body_n which_o can_v never_o be_v consider_v its_o tenderness_n if_o it_o be_v so_o rake_v by_o all_o sort_n of_o fume_n for_o then_o doubtless_o such_o a_o body_n will_v be_v most_o change_v of_o any_o in_o colour_n substance_n texture_n bigness_n etc._n etc._n what_o will_v become_v of_o memory_n and_o indeed_o of_o all_o the_o faculty_n of_o the_o brain_n can_v a_o soft_a yield_a substance_n continual_o discompose_v preserve_v impression_n make_v thereon_o if_o fume_n flow_v continual_o through_o the_o brain_n they_o must_v wear_v out_o all_o impression_n yea_o and_o the_o brain_n itself_o in_o a_o short_a time_n 11._o it_o will_v be_v very_o dangerous_a to_o eat_v or_o drink_v if_o the_o brain_n must_v suffer_v so_o much_o by_o the_o fume_n of_o meat_n wine_n etc._n etc._n it_o will_v be_v hard_a to_o know_v whether_o it_o be_v best_a to_o eat_v or_o not_o for_o both_o must_v be_v fatal_a 12._o what_o a_o vast_a difference_n shall_v we_o observe_v as_o to_o serenity_n of_o mind_n etc._n etc._n when_o empty_a and_o full_a for_o in_o this_o last_o case_n the_o brain_n must_v be_v all_o in_o a_o cloud_n or_o a_o cloud_n in_o it_o or_o both_o yet_o be_v man_n much_o more_o serenâ—_n prompt_v and_o fit_a for_o any_o thing_n after_o some_o glass_n of_o wine_n than_o before_o and_o after_o moderate_a eat_v than_o when_o hungry_a which_o make_v they_o faint_a peevish_a ill-humoured_a and_o listless_a 13._o if_o the_o vapour_n or_o fume_n of_o opium_n fly_v up_o to_o the_o brain_n cause_v all_o its_o effect_n it_o be_v very_o strange_a that_o our_o fumi_fw-la venduli_fw-la have_v not_o long_o since_o find_v out_o the_o mountebank_n gambol_n of_o stand_v upon_o their_o head_n to_o prevent_v all_o mischief_n from_o opium_n take_v in_o a_o great_a do_v for_o fume_n in_o a_o warm_a live_a body_n will_v not_o descend_v into_o the_o head_n i_o wonder_v they_o do_v not_o find_v out_o such_o a_o easy_a and_o natural_a consequence_n of_o their_o hypothesis_n if_o true_a they_o may_v then_o have_v bold_o mount_v any_o stage_n free_o take_v opium_n in_o the_o sight_n of_o the_o admire_a rabble_n their_o summerset_n go_v upon_o their_o hand_n etc._n etc._n will_v have_v secure_v they_o and_o turn_v danger_n topsie-turvy_o by_o the_o help_n of_o a_o comical_a gesture_n this_o be_v indeed_o somewhat_o to_o purpose_n if_o it_o succeed_v if_o not_o i_o shall_v think_v it_o be_v enough_o to_o ridicule_n their_o hypothesis_n out_o of_o all_o credit_n without_o any_o far_a argument_n i_o dare_v join_v issue_n with_o they_o upon_o that_o point_n that_o it_o will_v not_o succeed_v though_o a_o necessary_a consequence_n of_o their_o opinion_n if_o true_a wherein_o they_o will_v have_v this_o advantage_n that_o they_o will_v confess_v with_o one_o that_o never_o do_v or_o will_v try_v it_o as_o be_v well_o assure_v of_o the_o falsity_n of_o both_o the_o hypothesis_n and_o the_o experiment_n without_o such_o a_o trial_n of_o skill_n now_o i_o think_v that_o i_o have_v say_v enough_o and_o will_v willing_o give_v over_o argue_v and_o spend_v any_o more_o time_n to_o confute_v a_o hypothesis_n so_o absurd_a that_o it_o must_v needs_o appear_v so_o to_o
the_o spirit_n by_o any_o mean_n for_o there_o be_v nothing_o so_o good_a in_o nature_n but_o will_v do_v it_o if_o use_v undue_o or_o immoderate_o as_o wine_n bread_n milk_n honey_n sugar_n beer_n etc._n etc._n in_o excess_n for_o i_o intend_v that_o it_o do_v not_o do_v it_o when_o due_o and_o moderate_o use_v 1._o that_o which_o refresh_v the_o weary_a and_o high_o prevent_v weariness_n must_v add_v to_o or_o excite_v the_o spirit_n which_o be_v direct_o contrary_a to_o diminish_v or_o disable_n they_o but_o opium_n do_v in_o a_o most_o eminent_a manner_n refresh_v the_o weary_v and_o prevent_v weariness_n therefore_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n some_o have_v be_v so_o silly_a and_o inadvertent_n as_o to_o object_n that_o it_o refresh_v the_o weary_a only_o by_o sleep_n it_o be_v matter_n of_o fact_n that_o it_o refresh_v they_o whether_o they_o sleep_v or_o no_o and_o that_o without_o fail_v as_o often_o as_o it_o be_v use_v in_o that_o case_n other_o that_o be_v no_o wise_a have_v say_v that_o it_o only_o take_v off_o the_o sense_n of_o weariness_n by_o stupify_a which_o happen_v by_o the_o diminish_n or_o disable_n of_o the_o animal_n spirit_n bare_a insensibleness_n can_v enable_v the_o spirit_n to_o labour_n with_o eminent_a briskness_n and_o alacrity_n as_o man_n most_o certain_o do_v after_o opium_n be_v take_v be_v fine_o enliven_v and_o invigorate_v as_o with_o generous_a wine_n if_o they_o do_v not_o know_v this_o to_o be_v true_a let_v they_o for_o shame_n hold_v their_o tongue_n till_o they_o know_v matter_n of_o fact_n which_o if_o they_o will_v not_o they_o proclaim_v themselves_o to_o be_v idle_a and_o impertinent_a babbler_n but_o if_o they_o will_v patient_o and_o wise_o abstain_v argue_v till_o they_o be_v satisfy_v as_o to_o matter_n of_o fact_n then_o will_v they_o be_v past_a opinion_n and_o hypothesis_n in_o that_o case_n for_o they_o will_v have_v sensible_a and_o certain_a knowledge_n of_o the_o contrary_a and_o the_o truth_n of_o what_o i_o say_v which_o will_v end_v all_o controversy_n and_o precarious_a squabble_n upon_o false_a supposition_n as_o the_o manner_n be_v that_o can_v lead_v they_o to_o what_o be_v right_o but_o by_o mere_a chance_n and_o never_o to_o a_o true_a knowledge_n that_o they_o be_v in_o the_o right_n which_o make_v it_o none_o in_o effect_n for_o they_o can_v do_v nothing_o with_o assurance_n but_o only_o suppose_v and_o hope_v they_o be_v in_o the_o right_n when_o they_o be_v as_o much_o out_o to_o their_o patient_n sorrow_n as_o physician_n have_v be_v in_o the_o cold_a quality_n and_o fume_n of_o opium_n it_o be_v true_a that_o a_o grain_n or_o two_o of_o opium_n will_n if_o a_o man_n compose_v himself_o sit_v or_o lie_v still_o cause_n a_o sleepiness_n equal_a to_o that_o cause_v by_o spend_v the_o spirit_n by_o a_o day_n be_v labour_n but_o spend_v of_o the_o spirit_n be_v not_o the_o only_a no_o nor_o best_a proportion_v or_o more_o adequate_a cause_n thereof_o as_o i_o have_v show_v if_o loss_n of_o spirit_n be_v the_o adequate_a cause_n of_o sleep_n how_o shall_v good_a and_o generous_a wine_n cause_n sleepiness_n after_o that_o eminent_a rate_n as_o it_o do_v in_o most_o people_n how_o shall_v the_o most_o please_a music_n incline_v such_o as_o lie_v or_o sit_v still_o to_o sleep_v but_o if_o one_o dance_n thereto_o it_o make_v he_o more_o lively_a and_o brisk_a than_o ordinary_a the_o like_a exact_o do_v wine_n and_o opium_n if_o man_n lie_v or_o sit_v still_o but_o otherwise_o they_o make_v they_o much_o more_o brisk_a and_o lively_a and_o able_a to_o undergo_v labour_n action_n etc._n etc._n which_o note_n that_o you_o may_v not_o any_o more_o wonder_n that_o enlivener_n and_o exciter_n of_o the_o spirit_n do_v cause_n sleep_v as_o well_o as_o diminisher_n thereof_o and_o observe_v that_o they_o be_v all_o please_a thing_n as_o music_n wine_n and_o opium_n which_o cause_n pleasant_a dream_n pleasant_a watch_n pleasant_a humour_n etc._n etc._n expect_v more_o of_o this_o matter_n in_o the_o follow_a chapter_n and_o all_o by_o degree_n according_a as_o i_o judge_v the_o prejudice_v world_n will_v bear_v thing_n for_o a_o great_a paradox_n how_o true_a soever_o must_v not_o be_v abrupt_o obtrude_v but_o gentle_o and_o gradual_o usher_v in_o by_o insinuate_v reason_v otherwise_o it_o will_v be_v entertain_v like_o a_o rude_a stranger_n that_o contradict_v a_o multitude_n in_o fashion_n and_o custom_n that_o they_o have_v always_o use_v and_o judge_v to_o be_v the_o very_o best_o however_o unblamable_a consider_v that_o if_o opium_n diminish_v or_o disable_v the_o spirit_n proportionable_a to_o the_o sleepiness_n that_o it_o cause_n as_o a_o hard_a day_n be_v labour_n do_v then_o if_o opium_n be_v give_v a_o man_n after_o a_o hard_a day_n be_v labour_n it_o will_v be_v as_o it_o be_v add_v another_o hard_a day_n be_v labour_v to_o cure_v it_o the_o day_n be_v labour_n and_o opium_n impair_n the_o spirit_n alike_o think_v what_o a_o miserable_a condition_n the_o poor_a man_n will_v be_v in_o especial_o if_o sleep_n do_v not_o make_v he_o some_o amends_o it_o will_v be_v such_o as_o be_v utter_o intolerable_a but_o so_o far_o be_v opium_n from_o any_o such_o effect_n that_o it_o refresh_v he_o though_o he_o sleep_v not_o at_o all_o after_o the_o hard_a day_n be_v labour_n and_o not_o only_o so_o but_o will_v enable_v he_o to_o work_v all_o the_o follow_a night_n with_o great_a alacrity_n if_o need_n require_v it_o what_o a_o condition_n will_v those_o be_v in_o who_o take_v a_o drachm_n of_o it_o twice_o a_o day_n for_o 10_o 20_o or_o 30_o year_n nay_o how_o can_v any_o possible_o do_v it_o for_o half_a 10_o day_n if_o a_o grain_n or_o two_o destroy_v the_o spirit_n so_o much_o as_o to_o cause_v sleepiness_n thereby_o as_o hard_a labour_n do_v which_o they_o must_v allow_v that_o assert_v it_o cause_n sleep_v by_o diminish_v or_o disable_n the_o spirit_n but_o some_o may_v say_v though_o very_o inconsiderate_o that_o it_o only_o disable_v they_o for_o the_o time_n of_o its_o operation_n that_o be_v strange_a indeed_o consider_v that_o even_o during_o that_o time_n they_o be_v most_o enable_v to_o work_n or_o labour_n though_o tire_v before_o and_o that_o it_o 2._o cause_n comfort_n refreshment_n ovation_n of_o the_o spirit_n all_o the_o time_n of_o its_o operation_n as_o wine_n moderate_o take_v do_v especial_o if_o people_n keep_v themselves_o in_o action_n labour_n etc._n etc._n otherwise_o indeed_o they_o may_v fall_v asleep_a upon_o the_o comfortable_a satisfaction_n contentation_n of_o mind_n and_o acquiescence_n of_o spirit_n that_o it_o occasion_n as_o wine_n do_v 3._o the_o first_o effect_n that_o we_o find_v of_o opium_n which_o may_v therefore_o probable_o be_v a_o very_a lead_n fundamental_a and_o significant_a effect_n be_v that_o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o incline_v he_o to_o sleep_n if_o not_o it_o make_v he_o gay_a good_a humour_a brave_a etc._n etc._n it_o be_v a_o pleasure_n so_o sweet_a and_o delicious_a that_o though_o i_o endeavour_v to_o express_v it_o by_o the_o ovation_n of_o the_o spirit_n upon_o joy_n a_o good_a genius_n inform_v a_o man_n or_o the_o helmâ—sians_n archaeus_n in_o his_o best_a humour_n or_o a_o continual_a vâ—real_a pleasure_n wine_n drink_v ad_fw-la hilaritatem_fw-la etc._n etc._n yet_o i_o doubt_v all_o my_o way_n of_o express_v it_o do_v come_v short_a of_o the_o charm_a complacency_n that_o it_o cause_n therefore_o if_o wine_n music_n a_o good_a meal_n agreeable_a frication_n of_o the_o head_n or_o back_o the_o sound_n of_o water_n etc._n etc._n do_v incline_v we_o to_o sleep_v by_o the_o pleasure_n thereof_o which_o lull_v and_o soothe_v we_o to_o it_o as_o be_v most_o certain_a if_o we_o sit_v or_o lie_v still_o much_o more_o must_v the_o high_a charm_n of_o opium_n cause_n it_o that_o it_o be_v a_o pleasure_n that_o affect_v by_o one_o of_o our_o sense_n namely_o by_o feel_v be_v indisputable_a for_o it_o be_v not_o a_o pleasure_n of_o the_o eye_n nose_n tongue_n or_o ear_n and_o it_o must_v be_v sensitive_a because_o cause_v by_o matter_n and_o that_o opium_n have_v doubtless_o the_o like_a effect_n upon_o brute_n who_o have_v no_o other_o pleasure_n but_o what_o be_v sensitive_a that_o it_o be_v at_o stomach_n be_v also_o evident_a where_o we_o can_v be_v please_v only_o by_o the_o sense_n of_o feel_v that_o it_o be_v involuntary_a and_o please_v we_o whether_o we_o will_v or_o no_o and_o that_o the_o same_o particle_n excite_v venery_n itch_a etc._n etc._n now_o all_o the_o sense_n especial_o feel_v and_o particular_o that_o at_o stomach_n be_v give_v we_o for_o
sensation_n of_o the_o sensile_a part_n which_o can_v well_o happen_v in_o that_o sound_a sleep_n wherein_o there_o be_v so_o little_a feel_v by_o reason_n of_o the_o say_a relaxation_n and_o because_o relaxation_n oppose_v contraction_n by_o which_o that_o shiver_a be_v promote_v such_o a_o relaxation_n and_o failure_n of_o feel_v thereupon_o be_v the_o true_a cause_n why_o opium_n put_v off_o ague_n fit_n etc._n etc._n so_o 20._o the_o relaxation_n in_o sleep_n stop_v vomit_v by_o take_v away_o the_o sense_n of_o the_o irritate_v cause_n and_o quiet_v as_o i_o have_v intimate_v all_o motion_n in_o general_a so_o sleep_v stop_n hiccough_n hemorrhage_n diary_n fever_n etc._n etc._n 21._o why_o watch_v labour_n or_o what_o impair_v the_o spirit_n and_o tire_v the_o sensitive_a soul_n incline_v we_o to_o sleep_v that_o be_v dispose_v the_o sensitive_a soul_n the_o only_a feeler_n of_o lassitude_n to_o give_v over_o contract_n the_o sensile_a part_n which_o as_o will_v plain_o appear_v by_o and_o by_o spend_v the_o spirit_n as_o sleep_v by_o relax_v they_o cause_v a_o recruit_v thereof_o to_o be_v short_a though_o one_o can_v hardly_o be_v too_o long_o in_o solve_v phenomena_n which_o be_v the_o proof_n of_o the_o truth_n of_o a_o man_n assertion_n the_o mechanical_a demonstration_n that_o i_o have_v make_v of_o the_o state_n of_o sleep_v and_o wake_v do_v so_o evident_o explicate_v all_o the_o phenomena_n of_o both_o that_o i_o be_o even_o ashamed_a to_o run_v any_o far_o upon_o such_o plain_a matter_n so_o obvious_a be_v thing_n when_o the_o truth_n be_v know_v and_o therefore_o have_v mention_v those_o circumstance_n and_o effect_n of_o sleep_n that_o main_o concern_v we_o i_o must_v give_v over_o lest_o the_o world_n shall_v think_v that_o i_o take_v all_o my_o reader_n to_o be_v idiot_n by_o use_v too_o many_o word_n in_o so_o obvious_a a_o thing_n or_o that_o i_o be_o no_o better_o for_o use_v they_o without_o cause_n for_o the_o truth_n of_o this_o matter_n seem_v to_o i_o to_o outshine_v all_o the_o argument_n i_o can_v make_v for_o it_o such_o splendour_n do_v truth_n show_v upon_o the_o first_o glimpse_n thereof_o as_o i_o take_v the_o account_n i_o give_v of_o sleep_n and_o watch_v to_o be_v for_o the_o opinion_n i_o have_v meet_v concern_v they_o be_v quite_o contrary_a to_o or_o very_o remote_a from_o what_o i_o have_v state_v 1._o they_o go_v quite_o contrary_a to_o it_o that_o say_v that_o the_o animal_n spirit_n be_v expanded_a and_o the_o pore_n of_o the_o brain_n etc._n etc._n more_o open_a and_o consequent_o more_o lax_n in_o watch_v as_o willis_n and_o several_a other_o who_o therefore_o say_v that_o coffee_n volatile_a salt_n etc._n etc._n be_v antihypnotick_n or_o good_a against_o too_o much_o sleepiness_n because_o they_o cause_v a_o expansion_n of_o the_o spirit_n and_o open_v the_o pore_n of_o the_o brain_n suppose_v forsooth_o that_o they_o march_v up_o and_o down_o and_o so_o keep_v the_o great_a stir_n upon_o the_o false_a imagination_n of_o their_o road_n be_v more_o open_a which_o as_o be_v prove_v be_v real_o more_o close_a coffee_n keep_v we_o from_o sleep_n by_o dry_v bind_a and_o both_o way_n constr_v the_o vessel_n as_o also_o by_o a_o wide_a grate_a quality_n which_o therefore_o do_v irritate_fw-la they_o to_o contract_v beside_o that_o the_o saline_n particle_n cause_v a_o agitation_n may_v contribute_v thereto_o so_o that_o by_o constr_v and_o agitate_v it_o direct_o oppose_v sleep_n which_o proceed_v from_o relaxation_n and_o quietness_n 2._o they_o be_v very_o remote_a from_o the_o mark_n that_o say_v as_o wedeliâ—s_a assert_n all_o do_v that_o vapour_n be_v the_o cause_n of_o natural_a sleep_n which_o bear_v no_o manner_n of_o proportion_n thereto_o as_o be_v show_v as_o they_o be_v also_o who_o mâ—dly_o talk_v that_o the_o animal_n spirit_n which_o have_v neither_o life_n sense_n motion_n or_o election_n do_v of_o themselves_o retire_v very_o know_o to_o the_o brain_n in_o sâ—eep_n and_o leave_v the_o limb_n etc._n etc._n destitute_a of_o they_o whereas_o as_o have_v be_v mechanical_o prove_v they_o have_v more_o room_n than_o that_o at_o other_o time_n in_o 〈◊〉_d limb_n and_o all_o the_o sensile_a part_n but_o i_o will_v not_o argue_v against_o such_o senseless_a and_o precarious_a absurdity_n it_o be_v not_o worth_a the_o while_n especial_o since_o the_o truth_n be_v manifest_o discover_v it_o will_v not_o have_v be_v so_o silly_a to_o have_v affirm_v the_o quite_o contrary_a viz._n that_o the_o animal_n spirit_n be_v force_v into_o the_o soft_a and_o yield_a brain_n in_o watch_v by_o the_o vigilative_a contraction_n of_o all_o the_o senfile_v part_n repel_v they_o as_o when_o cold_a repel_v they_o by_o a_o strong_a contraction_n of_o the_o part_n and_o cause_v a_o stupor_n or_o sleep_n thereof_o as_o they_o call_v it_o but_o what_o have_v we_o to_o do_v with_o such_o insufferable_a trash_n therefore_o bid_v it_o adieu_n let_v we_o pursue_v our_o business_n that_o it_o be_v the_o sensitive_a soul_n and_o nothing_o but_o it_o have_v that_o contract_n power_n be_v evident_a 1._o because_o it_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n as_o such_o and_o that_o nothing_o beside_o it_o have_v any_o life_n perception_n motion_n or_o power_n and_o therefore_o must_v rest_v till_o they_o be_v move_v 2._o because_o that_o when_o the_o sensitive_a soul_n be_v divert_v by_o intense_a pleasure_n from_o attend_v his_o business_n immediate_o relaxation_n follow_v as_o in_o the_o pleasure_n of_o the_o act_n of_o venery_n by_o wine_n joy_n etc._n etc._n in_o which_o you_o have_v all_o the_o effect_n of_o relaxation_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la plentiful_a perspiration_n floridity_n of_o the_o skin_n a_o large_a pulse_n and_o sometime_o a_o considerable_a failure_n of_o sense_n and_o motion_n as_o in_o the_o most_o pleasant_a time_n of_o the_o venereal_a act_n deliquiums_n drunkenness_n syncopes_fw-la or_o ecstasy_n upon_o intense_a pleasure_n which_o be_v very_o proper_o call_v ecstasy_n leipothymy_n leipopsychy_n etc._n etc._n which_o signify_v the_o soul_n leave_v we_o without_o his_o help_n by_o contraction_n which_o he_o then_o do_v not_o exercise_n as_o be_v charm_v and_o whole_o take_v up_o with_o pleasure_n this_o be_v the_o true_a cause_n of_o all_o deliquium_n etc._n etc._n upon_o pleasure_n joy_n etc._n etc._n all_o which_o cause_n great_a relaxation_n and_o thereby_o loss_n of_o sense_n and_o motion_n as_o be_v its_o necessary_a consequence_n 3._o because_o grievous_a sensation_n which_o belong_v only_o to_o the_o sensitive_a soul_n put_v we_o immediate_o out_o of_o sleep_n into_o a_o vigilative_a contraction_n 4._o because_o the_o sensitive_a soul_n can_v when_o we_o be_v sleepy_a oppose_v it_o by_o continue_v the_o vigilative_a contraction_n which_o prove_v vigilative_a contraction_n to_o be_v in_o his_o power_n note_v that_o there_o be_v also_o other_o sort_n of_o leipothymy_n deliquium_n etc._n etc._n upon_o the_o sensitive_a soul_n be_v overtired_n whereof_o natural_a sleep_n be_v but_o a_o common_a and_o ordinary_a degree_n that_o happen_v of_o course_n for_o our_o relief_n or_o overbear_v with_o some_o fatigue_n etc._n etc._n as_o when_o somewhat_o grieve_v at_o stomach_n and_o that_o it_o have_v lay_v about_o it_o all_o manner_n of_o way_n by_o vomit_v convulsive_a motion_n etc._n etc._n to_o be_v rid_v of_o it_o till_o it_o can_v work_v no_o long_o whereupon_o it_o lay_v down_o the_o cudgel_n desi_v from_o all_o further_a endeavour_n by_o contraction_n yield_v itself_o to_o ease_n see_v all_o strive_v be_v to_o no_o effect_n so_o that_o though_o this_o deliquium_fw-la and_o the_o former_a differ_v in_o their_o first_o cause_n yet_o do_v they_o agree_v in_o the_o last_o and_o immediate_a viz._n the_o sensitive_a soul_n be_v not_o attend_v his_o business_n of_o contraction_n whereupon_o follow_v a_o mighty_a relaxation_n as_o appear_v by_o the_o deadness_n or_o relaxation_n of_o the_o cornea_n dilatation_n of_o the_o pupil_n a_o great_a laxity_n of_o all_o part_n a_o large_a pulse_n or_o none_o very_o plentiful_a perspiration_n stop_v of_o hemorrhage_n and_o all_o flux_n that_o require_v contraction_n etc._n etc._n which_o happen_v both_o upon_o the_o account_n of_o the_o great_a relaxation_n itself_o as_o have_v be_v show_v and_o the_o almost_o absolute_a rest_n of_o all_o thing_n by_o the_o sensitive_a soul_n withdraw_a himself_n from_o business_n more_o than_o in_o sleep_n itself_o i_o therefore_o observe_v the_o degree_n of_o sleep_n etc._n etc._n do_v note_n that_o god_n and_o nature_n use_v a_o due_a proportion_n in_o all_o thing_n the_o sensitive_a soul_n use_v several_a degree_n of_o relaxation_n according_a as_o he_o be_v tire_v and_o refection_n be_v want_v hence_o it_o be_v that_o such_o as_o be_v much_o tire_v sleep_n more_o profound_o that_o our_o first_o
sleep_v be_v the_o sound_a and_o that_o sleep_v gradual_o decline_v in_o degree_n as_o we_o be_v recruit_v till_o we_o awake_v the_o near_a which_o we_o be_v the_o more_o we_o dream_v the_o state_n of_o dream_v be_v a_o kind_n of_o twilight_n between_o sound_a sleep_n and_o awake_v or_o between_o a_o full_a somniferous_a relaxation_n and_o vigilative_a contraction_n and_o as_o the_o sensitive_a soul_n use_v all_o degree_n of_o contraction_n below_o that_o of_o the_o vigilative_a till_o it_o come_v to_o bare_a compression_n of_o the_o air_n so_o it_o can_v exercise_v super-vigilative_a contraction_n if_o i_o may_v so_o call_v it_o that_o be_v much_o high_a degree_n thereof_o than_o what_o be_v requisite_a ordinary_o for_o a_o state_n of_o vigilancy_n as_o in_o case_n of_o danger_n to_o the_o animal_n fright_v terror_n grievous_a passion_n and_o sensation_n by_o which_o mean_v the_o animal_n spirit_n be_v more_o compress_v than_o under_o the_o ordinary_a vigilative_a contraction_n sensation_n grow_v more_o nice_a and_o smart_a and_o motion_n more_o prompt_a and_o vigorous_a they_o always_o go_v together_o for_o the_o defence_n of_o the_o animal_n by_o extraordinary_a flight_n repulsion_n or_o otherwise_o hence_o it_o be_v upon_o fear_n terror_n grievous_a passion_n or_o sensation_n which_o manifest_o prove_v the_o be_v of_o such_o a_o extraordinary_a contraction_n upon_o such_o occasion_n that_o 1._o perspiration_n sail_v in_o a_o yet_o high_o degree_n than_o under_o bare_a or_o ordinary_a vigilative_a contraction_n as_o appear_v by_o infallible_a statick_a experiment_n and_o demonstration_n 2._o it_o be_v by_o reason_n of_o the_o say_v defensive_a contraction_n for_o so_o i_o call_v it_o because_o it_o be_v excite_v in_o a_o extraordinary_a manner_n for_o the_o defence_n of_o the_o animal_n in_o time_n of_o need_n or_o great_a exigence_n that_o in_o fright_v terror_n etc._n etc._n our_o hair_n dog_n etc._n etc._n do_v stand_v on_o end_n or_o more_o upright_o 1._o because_o the_o pore_n do_v by_o that_o violent_a contraction_n strict_o close_a about_o the_o root_n of_o the_o hair_n that_o it_o can_v swag_v incline_v or_o yield_v any_o way_n by_o reason_n of_o its_o weight_n etc._n etc._n as_o when_o the_o skin_n be_v more_o lax_n and_o soft_a and_o the_o pore_n wherein_o the_o hair_n be_v fix_v more_o open_a 2._o because_o which_o be_v the_o main_a reason_n the_o say_a contraction_n render_v the_o oblique_a pore_n more_o upright_o as_o suppose_v the_o pore_n and_o hair_n do_v natural_o stand_v oblique_o as_o they_o do_v to_o carry_v off_o wet_a etc._n etc._n as_o in_o fig._n 1._o fig_n i_o fig_n two_o and_o that_o a_o in_o fig._n 1._o be_v by_o the_o say_a contraction_n bring_v near_a to_o ay_o as_o much_o as_o be_v from_o a_o to_o o_o then_o will_v the_o pore_n and_o hair_n stand_v upright_o as_o in_o fig._n 2._o and_o the_o skin_n a_o o_o e_o i_o s_o contract_v and_o bring_v within_o the_o prick_v perpendicular_o whereas_o in_o fig._n 1._o it_o excure_v beyond_o the_o perpendicular_a n_z m_z as_o much_o as_o be_v from_o a_o to_o o._n 3._o for_o the_o same_o reason_n it_o be_v that_o the_o face_n in_o grievous_a passion_n and_o sensation_n as_o acute_a pain_n etc._n etc._n be_v contort_a and_o wring_v awry_o as_o you_o see_v in_o person_n that_o cry_v because_o of_o grievance_n after_o the_o same_o manner_n as_o when_o they_o strive_v to_o lift_v up_o a_o great_a weight_n and_o that_o at_o the_o same_o time_n tear_n and_o moisture_n at_o nose_n and_o mouth_n be_v squeeze_v out_o by_o the_o same_o contraction_n which_o make_v people_n use_v the_o say_v of_o casting_n snot_n about_o when_o man_n cry_v it_o be_v for_o the_o same_o reason_n that_o people_n mouth_n water_n extreme_o when_o they_o be_v trim_v with_o a_o bad_a razor_n that_o put_v they_o to_o pain_n which_o contract_v the_o part_n and_o squeeze_v out_o the_o spital_n 4._o the_o pulse_n grow_v sensible_o narrow_a and_o hard_a by_o the_o same_o contraction_n 5._o it_o be_v by_o the_o contraction_n upon_o grievous_a sensation_n that_o our_o mouth_n water_n very_o much_o upon_o a_o nausea_n at_o stomach_n because_o of_o the_o continuity_n of_o the_o membrane_n of_o the_o mouth_n and_o stomach_n 6._o the_o same_o contraction_n be_v the_o true_a reason_n why_o people_n upon_o hunger_n which_o be_v a_o grievous_a sensation_n at_o stomach_n have_v so_o much_o moisture_n or_o spital_n in_o their_o mouth_n and_o so_o much_o the_o more_o when_o they_o see_v good_a victual_n and_o can_v have_v it_o because_o the_o grievance_n which_o cause_v the_o contraction_n that_o squeeze_v it_o out_o be_v by_o so_o much_o the_o great_a this_o be_v the_o cause_n why_o the_o mouth_n water_n when_o hungry_a people_n see_v or_o smell_v good_a victual_n by_o the_o same_o contraction_n moisture_n be_v squeeze_v out_o into_o the_o oesophagus_n or_o gullet_n and_o the_o menstruum_fw-la into_o the_o stomach_n at_o the_o same_o time_n where_o observe_v god_n good_a and_o wise_a providence_n that_o hunger_n which_o call_v for_o meat_n at_o the_o same_o time_n provide_v spital_n to_o lubricate_v it_o for_o swollow_v and_o to_o help_v digestion_n render_v the_o gullet_n slippery_a and_o distensible_a and_o cause_v the_o menstruum_fw-la to_o flow_v more_o abundant_o into_o the_o stomach_n and_o all_o this_o when_o most_o need_v and_o that_o exact_o in_o proportion_n to_o the_o hunger_n or_o grievous_a sensation_n that_o cause_v the_o contraction_n it_o be_v well_o worth_a your_o nothing_o that_o god_n wisdom_n do_v always_o cause_v the_o want_n of_o what_o be_v necessary_a in_o sensile_a creature_n to_o be_v the_o solicit_v and_o urge_v cause_n for_o supply_v that_o a_o due_a proportion_n may_v be_v observe_v between_o the_o supply_n and_o the_o want_n which_o may_v upon_o the_o tell_n of_o it_o appear_v so_o plain_a a_o case_n that_o it_o be_v scarce_o worth_a the_o mention_v but_o believe_v i_o it_o be_v so_o little_o observe_v as_o plain_a as_o it_o may_v seem_v to_o be_v that_o people_n have_v and_o do_v err_v extravagant_o for_o want_n of_o note_v it_o which_o if_o they_o have_v note_v they_o can_v never_o have_v say_v that_o vapour_n or_o the_o retire_n of_o spirit_n into_o the_o brain_n etc._n etc._n be_v the_o cause_n or_o call_v of_o natural_a sleep_n nor_o feign_v menstruum_n to_o be_v the_o cause_n of_o hunger_n but_o will_v have_v due_o consider_v what_o be_v main_o supply_v by_o eat_v or_o recruit_v by_o sleep_v etc._n etc._n and_o then_o have_v nothing_o to_o do_v but_o to_o conclude_v the_o defect_n of_o that_o to_o have_v be_v the_o cause_n that_o solicit_v for_o the_o supply_n in_o proportion_n to_o the_o defect_n which_o if_o observe_v will_v most_o natural_o and_o easy_o lead_v you_o to_o the_o true_a knowledge_n of_o the_o cause_n of_o all_o appetite_n in_o a_o animal_n upon_o a_o few_o minute_n consideration_n for_o want_v of_o which_o most_o plain_a and_o one_o will_v think_v very_o obvious_a method_n the_o deviate_a world_n have_v sad_o puzzle_v itself_o about_o the_o cause_n of_o hunger_n thirst_v sleep_v and_o the_o like_a to_o this_o day_n and_o still_o be_v in_o dispute_n about_o they_o of_o which_o though_o my_o advertent_fw-la reader_n may_v well_o prevent_v i_o by_o use_v that_o natural_a method_n i_o shall_v god_n will_v give_v a_o account_n in_o my_o tract_n of_o animal_n mechanism_n only_a note_n here_o that_o i_o do_v not_o mean_v bare_a privative_a defect_n as_o such_o to_o be_v the_o positive_a cause_n but_o that_o the_o defect_n of_o what_o keep_v or_o guard_v the_o stomach_n etc._n etc._n from_o the_o grievance_n cause_v other_o matter_n to_o grieve_v it_o cause_n hunger_n etc._n etc._n without_o which_o mean_n no_o proportion_n can_v be_v observe_v between_o hunger_n and_o what_o take_v it_o away_o or_o our_o food_n 7._o the_o same_o defensive_a contraction_n do_v upon_o grievous_a sensation_n as_o pain_n cold_a terror_n etc._n etc._n cause_n a_o corrugation_n of_o the_o scrotum_fw-la contract_v the_o skin_n into_o little_a tubercle_n like_o that_o of_o a_o goose-skin_n etc._n etc._n 8._o by_o it_o upon_o grievous_a sensation_n as_o by_o squeeze_v the_o nose_n very_o hard_o pull_v the_o hair_n sand_n or_o any_o such_o thing_n in_o the_o eye_n or_o a_o grievance_n by_o the_o volatile_a particle_n of_o onion_n mustard_n horse-radish-root_n etc._n etc._n the_o part_n and_o membrane_n about_o the_o eye_n contract_v squeeze_v out_o tear_n that_o what_o grieve_v the_o eye_n may_v thereby_o be_v wash_v away_o or_o qualify_v as_o much_o as_o the_o tear_n can_v do_v it_o 9_o by_o this_o contraction_n repel_v the_o blood_n the_o skin_n grow_v pale_a by_o cold_a fear_v pain_n etc._n etc._n which_o also_o close_v the_o pore_n stop_v sweat_n as_o in_o a_o moment_n you_o will_v have_v a_o account_n hereafter_o how_o contraction_n may_v cause_v sweat_n
which_o have_v be_v in_o some_o measure_n enumerate_v in_o the_o case_n of_o natural_a sleep_n in_o this_o chapter_n viz._n satisfaction_n composure_n of_o fret_n and_o commotion_n as_o of_o diary_n fever_n hysterick_a fit_n etc._n etc._n perspiration_n quiet_v of_o vomit_n hiccough_n etc._n etc._n lessen_v of_o feel_v and_o consequent_o a_o stop_n and_o moderation_n of_o all_o flux_n that_o depend_v upon_o irritation_n of_o humour_n as_o diarrhea_n dysentery_n catarrh_n vomit_n dryness_n of_o the_o mouth_n as_o in_o sleep_n for_o want_v of_o the_o contraction_n to_o squeeze_v the_o spital_n out_o of_o the_o glandule_n into_o the_o mouth_n nocturnal_a pollution_n etc._n etc._n but_o of_o the_o nature_n and_o effect_n of_o pleasure_n you_o will_v find_v more_o in_o the_o next_o chapter_n beside_o the_o vigilative_a and_o defensive_a contraction_n which_o seem_v to_o be_v thing_n of_o course_n upon_o wake_v and_o grievance_n the_o sensitive_a soul_n have_v a_o contraction_n at_o will_n as_o that_o of_o the_o pupilla_fw-la when_o a_o animal_n be_v intent_n upon_o see_v of_o the_o tympan_n when_o intent_n upon_o hear_v of_o the_o musole_n of_o the_o leg_n when_o intent_n upon_o walk_v and_o so_o of_o all_o the_o muscle_n of_o the_o body_n which_o i_o call_v intentive_a contraction_n that_o he_o can_v perform_v either_o along_o with_o or_o without_o the_o other_o contraction_n or_o without_o any_o great_a degree_n thereof_o as_o when_o one_o be_v considerable_o relax_v with_o the_o pleasure_n of_o wine_n very_o good_a news_n etc._n etc._n nay_o sometime_o even_o in_o sleep_n as_o be_v manifest_a by_o the_o noctamâ—uli_n or_o such_o as_o walk_v in_o their_o sleep_n and_o such_o as_o speak_v strike_v etc._n etc._n while_o asleep_a and_o as_o the_o defensive_a contraction_n do_v all_o it_o can_v in_o our_o defence_n without_o the_o direction_n of_o the_o will_n as_o in_o vomit_v sneeze_n purge_v etc._n etc._n upon_o sensible_a irritation_n so_o this_o intentive_a contraction_n do_v all_o it_o can_v to_o the_o same_o purpose_n by_o the_o direction_n and_o dictate_v thereof_o note_v that_o insensile_a grow_a thing_n that_o do_v not_o move_v as_o tree_n etc._n etc._n have_v none_o of_o these_o contraction_n but_o what_o happen_v by_o cold_a and_o compression_n of_o the_o atmosphere_n which_o be_v sufficient_a it_o seem_v for_o nutrition_n but_o not_o for_o sense_n and_o motion_n it_o follow_v that_o in_o complete_a syncopes_fw-la when_o the_o sensitive_a soul_n give_v over_o all_o contraction_n that_o we_o be_v much_o in_o the_o state_n of_o a_o plant._n all_o those_o three_o contraction_n viz._n the_o vigilative_a defensive_a and_o intentive_a do_v because_o they_o promote_v motion_n and_o cause_v it_o more_o or_o less_o as_o you_o find_v the_o vigilative_a cause_n much_o more_o of_o it_o than_o sleep_v and_o the_o defensive_a more_o than_o that_o etc._n etc._n spend_v the_o spirit_n cause_n weariness_n etc._n etc._n the_o vigilative_a contraction_n do_v of_o itself_o without_o any_o considerable_a grievance_n or_o labour_n that_o be_v without_o the_o denfensive_a or_o intentive_a contraction_n tire_v the_o sensitive_a soul_n in_o about_o 16_o hour_n hence_o it_o be_v that_o the_o idle_v person_n that_o be_v most_o free_a from_o care_n trouble_v or_o pain_n can_v well_o hold_v out_o without_o the_o recruit_v of_o sleep_n any_o long_o the_o defensive_a contraction_n or_o that_o of_o grievance_n be_v add_v to_o the_o vigilative_a contraction_n the_o spirit_n be_v fast_o spend_v and_o the_o person_n tire_v proportionable_o soon_o according_a as_o the_o grievance_n be_v more_o or_o less_o and_o consequent_o the_o endeavour_n of_o the_o sensitive_a soul_n to_o be_v rid_v thereof_o to_o both_o which_o contraction_n viz._n the_o vigilative_a and_o defensive_a if_o you_o add_v the_o intentive_a or_o labour_n then_o be_v you_o soon_o and_o more_o tire_v than_o by_o only_a those_o two_o former_a contraction_n for_o this_o last_o case_n be_v labour_v in_o pain_n or_o under_o a_o grievance_n which_o notorious_o tire_v man_n or_o beast_n soon_o than_o ordinary_a the_o direct_a contrary_n to_o which_o be_v sleep_v sound_o and_o sweet_o without_o trouble_n pain_n or_o dream_n for_o a_o dream_a condition_n have_v too_o much_o of_o the_o vigilative_a contraction_n in_o it_o to_o be_v pure_a relaxation_n and_o recruit_v now_o according_a as_o these_o contraction_n be_v or_o be_v not_o add_v one_o to_o another_o we_o be_v soon_o or_o late_a before_o we_o be_v tire_v speak_v general_o and_o not_o consider_v custom_n and_o habit_n which_o concern_v we_o not_o you_o see_v that_o all_o the_o three_o contraction_n conour_v do_v soon_o and_o sad_o tire_v we_o that_o no_o two_o of_o they_o tire_v we_o as_o much_o as_o the_o three_o together_o that_o iâ—_n neither_o the_o vigilative_a and_o defensive_a without_o the_o intentive_a nor_o the_o vigilative_a and_o intentive_a without_o the_o defensive_a and_o the_o vigilative_a alone_o lest_o of_o all_o yet_o allowance_n must_v be_v make_v for_o the_o intenseness_n of_o the_o defensive_a and_o intentive_a for_o either_o of_o these_o two_o be_v very_a intense_a may_v tire_v as_o much_o as_o both_o in_o a_o moderate_a degree_n thus_o a_o man_n may_v be_v tire_v with_o violent_a labour_n in_o four_o hour_n though_o not_o in_o pain_n as_o much_o as_o one_o that_o moderate_o labour_v in_o some_o small_a pain_n for_o the_o same_o time_n observe_v that_o we_o recruit_v in_o eight_o hour_n general_o speak_v as_o much_o by_o relaxation_n in_o sleep_n as_o we_o spend_v by_o vigilative_a contraction_n in_o sixteen_o i_o take_v the_o reason_n of_o that_o to_o be_v that_o relaxation_n widen_v all_o the_o passage_n of_o the_o body_n the_o nutriment_n be_v admit_v into_o they_o more_o full_o and_o free_o as_o the_o blood_n be_v into_o the_o skin_n in_o sleep_n and_o all_o relaxation_n which_o cause_n a_o efflorescence_n thereof_o in_o those_o case_n hence_o it_o be_v that_o we_o be_v so_o much_o recruit_v and_o nourish_v in_o sleep_n that_o child_n grow_v more_o than_o other_o proportionable_o that_o relaxer_n cause_v the_o breast_n etc._n etc._n to_o grow_v note_v what_o a_o mighty_a restaurative_a relaxation_n be_v by_o its_o help_n for_o eight_o hour_n in_o twenty_o four_o we_o can_v watch_v all_o and_o labour_v most_o of_o the_o other_o sixteen_o all_o the_o day_n of_o our_o life_n it_o follow_v that_o if_o we_o can_v any_o way_n half_o relax_v the_o vigilative_a contraction_n while_o we_o labour_v take_v a_o journey_n or_o the_o like_a that_o we_o may_v perform_v prodigious_o without_o be_v â—ired_v hence_o it_o be_v that_o because_o pleasure_n as_o have_v be_v intimate_v relax_n as_o grievance_n contract_v of_o which_o you_o may_v expect_v far_a proof_n in_o the_o next_o chapter_n that_o such_o as_o work_v or_o travel_n pleasant_o divert_v all_o the_o time_n be_v tire_v very_o little_a or_o nothing_o in_o a_o long_a time_n and_o that_o some_o will_v dance_v whole_a nightâ—_n with_o sweet_a music_n and_o agreeable_a belove_a company_n without_o be_v so_o much_o tire_v as_o they_o will_v be_v if_o they_o use_v the_o same_o motion_n for_o a_o quarter_n of_o the_o time_n without_o either_o of_o the_o pleasant_a diversion_n the_o like_a be_v to_o be_v say_v of_o any_o other_o pleasure_n as_o drink_v a_o good_a glass_n of_o generous_a wine_n every_o half_a hour_n or_o so_o often_o as_o to_o continue_v the_o sense_n of_o its_o pleasure_n at_o stomach_n all_o the_o time_n they_o labour_v or_o travel_v for_o it_o be_v a_o vulgar_a error_n though_o the_o universal_a sentiment_n of_o mankind_n both_o learned_a and_o unlearned_a that_o wine_n cordial_n etc._n etc._n do_v comfort_n elevate_v and_o excite_v the_o spirit_n as_o it_o be_v call_v by_o add_v their_o spirit_n to_o or_o join_v they_o with_o we_o whereas_o it_o be_v only_o by_o cause_v a_o pleasant_a sensation_n particular_o at_o stomach_n for_o which_o paradox_n i_o be_o oblige_v though_o in_o great_a haste_n to_o come_v to_o the_o explication_n of_o opium_n to_o give_v my_o reason_n which_o be_v as_o follow_v viz._n 1._o it_o can_v be_v imagine_v how_o a_o sensitive_a creature_n as_o such_o can_v conceive_v any_o comfort_n or_o be_v sensible_a thereof_o but_o by_o sensation_n to_o say_v he_o be_v comfort_v and_o not_o sensible_a of_o the_o comfort_n be_v a_o contradiction_n for_o comfort_n as_o such_o belong_v to_o a_o perceive_v be_v and_o a_o animal_n as_o such_o perceive_v nothing_o but_o by_o the_o sense_n and_o therefore_o there_o can_v be_v no_o comfort_n but_o by_o pleasant_a sensation_n nay_o as_o such_o it_o be_v his_o comfort_n so_o music_n pleasant_a sight_n odour_n and_o agreeable_a object_n of_o all_o the_o sense_n be_v comfortable_a because_o pleasant_a i_o hope_v that_o none_o will_v say_v that_o music_n sight_n good_a news_n &c._n &c._n which_o high_o comfort_n have_v any_o spirit_n to_o add_v to_o we_o the_o
only_o the_o open_n of_o the_o pore_n so_o that_o i_o need_v add_v no_o more_o word_n about_o it_o for_o the_o fame_n cause_o must_v have_v the_o same_o effect_n therefore_o a_o intense_a and_o permanent_a pleasure_n must_v have_v all_o or_o much_o of_o the_o effect_n of_o sleep_n in_o general_n as_o have_v be_v show_v it_o can_v therefore_o be_v any_o wonder_n that_o opium_n cause_v sleep_n yet_o be_v there_o difference_n between_o sleep_n and_o pleasure_n upon_o other_o account_n though_o not_o upon_o the_o account_n of_o relaxation_n viz._n because_o 1._o that_o sleep_n require_v also_o a_o rest_n of_o spirit_n or_o the_o sensitive_a soul_n whereas_o relaxation_n by_o pleasure_n be_v consistent_a with_o motion_n of_o the_o spirit_n either_o by_o outward_a action_n or_o internal_a motion_n thereof_o by_o some_o inward_a cause_n hence_o it_o be_v first_o that_o we_o can_v labour_v travel_v dance_n etc._n etc._n and_o enjoy_v pleasure_n and_o its_o relaxation_n volantary_a motion_n which_o require_v only_o a_o particular_a contraction_n of_o some_o part_n by_o the_o dictate_v of_o the_o will_n or_o appetite_n be_v consistent_a with_o the_o general_a relaxation_n by_o reason_n of_o the_o prerogative_n of_o the_o will._n thus_o do_v we_o move_v though_o more_o relax_v or_o when_o most_o merry_a and_o please_v with_o wine_n nay_o some_o will_v walk_v in_o their_o sleep_n when_o extreme_o intâ—t_v upon_o a_o thing_n as_o when_o awake_a which_o show_v the_o roll_a power_n of_o intentive_a contraction_n that_o may_v be_v exercise_v with_o relaxation_n and_o other_o contraction_n as_o the_o will_n itself_o may_v or_o intentive_a appetite_n second_o that_o pain_n be_v often_o take_v away_o by_o opium_n by_o the_o diversion_n and_o relaxation_n cause_v by_o pleasure_n and_o its_o inconsistence_n with_o pain_n without_o sleep_n which_o require_v the_o aforesaid_a rest_n that_o bare_a relaxation_n as_o such_o do_v not_o include_v though_o relaxation_n suffice_v to_o take_v away_o pain_n three_o that_o opium_n do_v by_o its_o heat_n active_a particle_n etc._n etc._n hinder_v some_o person_n to_o sleep_n yet_o have_v you_o in_o both_o these_o last_o case_n all_o other_o effect_n of_o opium_n as_o pleasure_n indolence_n relaxation_n etc._n etc._n which_o show_v how_o far_o sleep_v be_v from_o be_v a_o constant_a and_o the_o most_o genuine_a effect_n of_o opium_n as_o be_v general_o imagine_v however_o we_o must_v allow_v it_o as_o have_v be_v show_v to_o be_v a_o mighty_a disposer_n of_o we_o towards_o sleep_n because_o of_o the_o relaxation_n that_o it_o cause_n which_o be_v the_o main_a requisite_a of_o sleep_n ii_o that_o pleasure_n do_v without_o nutritive_a refection_n by_o the_o complacency_n it_o cause_v in_o the_o sensitive_a soul_n produce_v comfort_n satisfaction_n composure_n elevation_n of_o the_o spirit_n euphory_n etc._n etc._n of_o which_o sleep_n be_v either_o not_o at_o all_o capable_a or_o but_o in_o a_o low_a degree_n proportionable_a to_o the_o sensation_n that_o it_o have_v which_o be_v but_o little_a however_o a_o pleasure_n that_o remain_v within_o we_o even_o in_o our_o sleep_n as_o that_o of_o opium_n may_v well_o cause_v pleasant_a dream_n etc._n etc._n the_o reader_n may_v observe_v that_o in_o all_o place_n where_o i_o mention_v that_o relaxation_n cause_v the_o open_n of_o the_o pore_n that_o i_o speak_v only_o of_o perspiration_n as_o the_o effect_n thereof_o without_o mention_v sweat_n 1._o because_o perspiration_n be_v the_o only_a constant_a and_o infallible_a effect_n thereof_o by_o reason_n that_o the_o levity_n of_o the_o fume_n cause_v they_o as_o certain_o to_o pass_v at_o the_o pore_n when_o open_a as_o smoke_n pass_v up_o at_o a_o open_a chimney_n 2._o because_o sweat_n be_v a_o uncertain_a effect_n thereof_o for_o it_o require_v that_o the_o body_n be_v well_o fill_v with_o moisture_n though_o there_o be_v a_o relaxation_n or_o open_v of_o the_o pore_n as_o hypocrates_n very_o right_o intimate_v in_o that_o aphorism_n of_o his_o that_o i_o cite_v in_o the_o last_o chapter_n 1._o because_o sweat_n have_v not_o that_o levity_n that_o the_o fume_n have_v to_o cause_v it_o ready_o to_o move_v as_o soon_o as_o the_o pore_n be_v open_a 2._o because_o relaxation_n be_v more_o apt_a to_o receive_v detain_v and_o suspend_v humour_n 3._o because_o the_o protrusive_a motion_n of_o the_o heart_n be_v weak_a in_o all_o relaxation_n and_o all_o see_v how_o much_o its_o vigorous_a protrusion_n contribute_v to_o sweat_v upon_o action_n 4._o because_o a_o heartful_a of_o blood_n do_v not_o make_v such_o a_o push_v forward_o when_o the_o artery_n be_v widen_v by_o relaxation_n 5._o sweat_n have_v more_o of_o continuity_n consistence_n and_o viscidity_n can_v flow_v out_o so_o ready_o at_o the_o pore_n as_o a_o mere_a vapour_n however_o if_o the_o body_n be_v full_a of_o moisture_n and_o the_o pore_n open_a there_o be_v a_o natural_a course_n that_o way_n and_o the_o heart_n continual_o protrude_a it_o far_o and_o far_o a_o sweat_n follow_v and_o that_o whether_o they_o sleep_v or_o not_o 3._o because_o sweat_v as_o be_v in_o some_o sort_n intimate_v be_v sometime_o cause_v by_o the_o strong_a protrusion_n of_o the_o heart_n as_o in_o motion_n etc._n etc._n and_o upon_o that_o account_n come_v more_o under_o the_o title_n of_o flux_n cause_v by_o contraction_n than_o relaxation_n of_o which_o perspiration_n be_v a_o constant_a effect_n 4._o because_o sweat_n be_v sometime_o cause_v by_o another_o sort_n of_o contraction_n viz._n the_o compression_n of_o the_o whole_a body_n by_o a_o violent_a defensive_a contraction_n as_o in_o great_a terror_n agony_n and_o the_o like_a cause_v thereby_o as_o be_v show_v by_o the_o comparison_n of_o a_o wet_a sheet_n wring_v who_o out_o side_n be_v cold_a a_o cold_a sweat_n which_o that_o of_o alum_n or_o vitriol_n cause_v a_o exudation_n of_o the_o spital_n into_o the_o mouth_n by_o constr_v the_o part_n do_v illustrate_v very_o plain_o therefore_o you_o see_v i_o have_v just_a cause_n not_o to_o mention_v sweat_n as_o a_o certain_a and_o proper_a effect_n of_o relaxation_n without_o good_a distinction_n first_o make_v though_o unwary_a author_n that_o talk_v any_o thing_n one_o after_o another_o not_o know_v what_o they_o say_v make_v it_o their_o common_a say_n that_o sleep_n and_o opium_n stop_v all_o flux_n but_o sweat_n whereas_o they_o shall_v have_v rather_o say_v but_o perspiration_n for_o opium_n and_o sleep_n also_o will_v sometime_o hinder_v sweat_n viz._n that_o from_o pain_n terror_n etc._n etc._n and_o that_o as_o happen_v just_a upon_o awake_v by_o the_o strong_a systole_n of_o the_o heart_n and_o contraction_n of_o the_o whole_a body_n and_o that_o also_o upon_o motion_n unless_o the_o body_n be_v as_o be_v say_v full_a of_o humour_n or_o moisture_n therefore_o it_o be_v a_o vulgar_a error_n to_o say_v sweat_n instead_o of_o perspiration_n in_o the_o case_n aforesaid_a you_o may_v remember_v that_o in_o the_o beginning_n of_o this_o chapter_n i_o conclude_v that_o a_o sal-volatile-oleosum_a such_o as_o semen_n humanum_fw-la wherein_o the_o oily_a and_o volatile_a part_n be_v strict_o combine_v and_o the_o volatile_a somewhat_o more_o active_a or_o acrimonious_a than_o that_o in_o our_o membrane_n in_o general_a must_v be_v most_o please_v to_o the_o membrane_n by_o a_o fine_a titillation_n etc._n etc._n therefore_o if_o opium_n shall_v prove_v to_o be_v such_o we_o need_v not_o wonder_v at_o its_o titillate_v to_o venery_n nor_o indeed_o its_o cause_v a_o high_a sense_n of_o pleasure_n upon_o any_o membrane_n they_o be_v all_o of_o the_o same_o nature_n but_o especial_o upon_o the_o most_o exquisite_o dispose_v membrane_n of_o the_o stomach_n and_o the_o venereal_a part_n nor_o consequent_o its_o cause_v all_o the_o aforementioned_a effect_n of_o intense_a pleasure_n as_o comfort_n satisfaction_n ovation_n etc._n etc._n of_o the_o sensitive_a soul_n or_o spirit_n and_o relaxation_n of_o all_o the_o sensile_a part_n which_o will_v easy_o solve_v all_o the_o phenomenas_n of_o opium_n however_o numerous_a mysterious_a and_o seem_o contradictory_n as_o you_o will_v find_v let_v we_o therefore_o now_o see_v whether_o opium_n be_v such_o a_o sal-volatile-oleosum_a wherein_o the_o volatile_a particle_n be_v somewhat_o more_o active_a or_o acrimonious_a than_o we_o and_o the_o oily_a and_o volatile_a part_n strict_o combine_v if_o so_o the_o business_n be_v do_v the_o nail_n be_v hit_v on_o the_o head_n and_o i_o may_v say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d chap._n xv._o show_v what_o be_v the_o principle_n of_o opium_n and_o which_o cause_n the_o good_a and_o bad_a effect_n thereof_o have_v try_v if_o not_o tire_v your_o patience_n and_o premise_v what_o i_o think_v necessary_a in_o the_o forego_n chapter_n i_o now_o reassume_v the_o thread_n of_o my_o discourse_n as_o for_o the_o passive_a principle_n of_o opium_n which_o do_v or_o signify_v little_a or_o nothing_o
spoon_n and_o cause_n no_o more_o effect_n than_o oil_n of_o olive_n and_o spirit_n of_o sal_fw-la amenoniack_a take_v inward_o one_o act_v too_o soft_o lazy_o and_o greasy_o to_o cause_v any_o brisk_a and_o agreeable_a ovation_n of_o the_o spirit_n and_o the_o other_o too_o rude_o sting_v the_o membrane_n therefore_o we_o must_v proceed_v in_o our_o enquiry_n four_o opium_n have_v a_o sort_n of_o resinous_n sulphur_n that_o be_v loose_a and_o not_o unite_v with_o the_o volatile_a salt_n which_o plain_o appear_v 1._o because_o if_o you_o dissolve_v opium_n in_o water_n cold_a or_o hot_a or_o any_o watery_a menstruum_fw-la you_o will_v find_v a_o good_a quantity_n of_o rosin_n undissolved_a at_o bottom_n while_o the_o volatile_a salt_n be_v all_o or_o most_o dissolve_v in_o the_o water_n especial_o if_o the_o water_n be_v often_o repeat_v and_o quite_o separate_v from_o the_o resinous_n part_v which_o subside_v without_o any_o more_o trouble_n which_o show_v that_o the_o volatile_a salt_n and_o it_o be_v not_o combine_v but_o in_o a_o very_a loose_a and_o distinct_a manner_n 2._o because_o if_o you_o first_o dissolve_v opium_n in_o spirit_n of_o wine_n which_o imbibe_v the_o rosin_n it_o be_v easy_o again_o precipitate_v by_o plain_a water_n leave_v behind_o it_o all_o or_o most_o of_o the_o volatile_a salt_n in_o the_o form_n of_o a_o red_a tincture_n in_o the_o menstruum_fw-la as_o it_o do_v also_o in_o the_o former_a case_n note_v that_o the_o resinous_n part_n of_o opium_n have_v no_o effect_n as_o a_o opiate_n for_o if_o it_o be_v well_o wash_v with_o water_n as_o be_v say_v it_o have_v no_o operation_n of_o that_o kind_n or_o so_o little_a that_o it_o be_v not_o worth_a the_o mind_v but_o all_o the_o virtue_n specific_a taste_n smell_v etc._n etc._n be_v carry_v away_o in_o that_o red_a tincture_n which_o have_v all_o the_o good_a effect_n of_o opium_n as_o experience_n assure_v we_o 3._o because_o if_o opium_n be_v very_o much_o torrefy_v most_o of_o the_o volatile_a salt_n be_v evaporate_v and_o with_o it_o most_o if_o not_o all_o the_o virtue_n of_o opium_n but_o the_o rosin_n remain_v as_o a_o deadish_a stuff_n in_o respect_n of_o the_o good_a effect_n of_o opium_n though_o it_o be_v as_o shall_v be_v prove_v the_o producer_n of_o the_o ill_a effect_n thereof_o therefore_o this_o rosin_n must_v be_v whole_o reject_v five_o the_o red_a tincture_n aforesaid_a have_v all_o or_o most_o of_o the_o volatile_a salt_n in_o it_o 1._o because_o water_n be_v the_o proper_a menstruum_fw-la for_o saline_n thing_n and_o that_o the_o tincture_n reduce_v to_o a_o extract_n give_v very_o much_o in_o moist_a wether_n which_o quality_n it_o must_v have_v from_o the_o volatile_a salt_n because_o it_o have_v very_o little_o fix_v salt_n 2._o because_o the_o specific_a bitterness_n which_o proceed_v from_o volatile_a salt_n and_o oily_a part_n be_v whole_o in_o that_o red_a tincture_n 3._o because_o that_o tincture_n have_v also_o the_o specific_a rankness_n of_o smell_n that_o the_o volatile_a salt_n as_o be_v show_v give_v the_o opium_n by_o the_o help_n of_o some_o oily_a part_n 4._o because_o that_o tincture_n reduce_v to_o a_o extract_n have_v the_o bite_a taste_n of_o opium_n which_o as_o be_v show_v proceed_v from_o its_o volatile_a salt_n 5._o because_o that_o extract_n incides_fw-la discuss_n resolve_n be_v psilothrick_n titillate_n to_o venery_n cause_v itch_n in_o the_o skin_n acrimonious_a sweat_v etc._n etc._n all_o which_o be_v as_o be_v show_v the_o effect_n of_o volatile_a salt_n but_o what_o need_v i_o insist_v so_o much_o upon_o its_o effect_n to_o prove_v it_o when_o 6._o it_o appear_v by_o crystalization_n of_o the_o say_a tincture_n after_o it_o have_v be_v evaporate_v to_o a_o due_a degree_n that_o it_o contain_v the_o volatile_a salt_n in_o it_o which_o in_o a_o cool_a place_n shoot_v to_o elegant_a crystal_n and_o that_o 7._o it_o be_v find_v therein_o by_o chemical_a operation_n by_o fire_n six_o the_o say_a tincture_n be_v oleose_v 1._o because_o the_o redness_n of_o the_o tincture_n must_v be_v from_o oily_a part_n for_o pure_a sincere_a volatile_a salt_n give_v no_o such_o tincture_n 2._o because_o it_o be_v bitter_a one_o ingredient_n of_o which_o taste_n be_v ever_o oily_a part_n as_o be_v say_v 3._o because_o of_o its_o rank_a smell_n like_o sem._n viril_n which_o prove_v it_o to_o be_v sulphureous_a for_o the_o volatile_a salt_n alone_o have_v only_o a_o quick_a smell_n or_o urinous_a at_o far_a 4._o because_o it_o be_v of_o a_o hot_a taste_n when_o reduce_v to_o a_o extract_n which_o heat_v of_o taste_n consider_v distinct_o from_o its_o pungent_a or_o bite_a taste_n must_v be_v from_o sulphureous_a or_o oily_a part_n 5._o because_o spirit_n of_o wine_n and_o other_o spirituosulphureous_a menstruum_n do_v ready_o dissolve_v it_o when_o reduce_v to_o a_o extract_n 6._o because_o the_o extract_n soften_v with_o dry_a warmth_n as_o sulphureous_a or_o oily_a thing_n do_v 7._o because_o a_o true_a sal-volatile-oleosum_a wherein_o the_o volatile_a salt_n and_o oily_a part_n be_v intimate_o combine_v as_o you_o find_v in_o all_o blood_n tincture_n of_o several_a plant_n that_o have_v such_o a_o sal-volatile-oleosum_a be_v red_a 8._o because_o it_o can_v not_o otherwise_o so_o fine_o please_v the_o membrane_n cause_n sleep_n compose_v the_o spirit_n etc._n etc._n if_o it_o be_v all_o volatile_a salt_n which_o be_v whole_o pungent_a and_o acrimonious_a mighty_o oppose_v sleep_n and_o cause_v a_o great_a stir_n in_o the_o blood_n and_o spirit_n but_o as_o i_o say_v as_o to_o its_o volatile_a salt_n what_o need_v i_o insist_v upon_o its_o effect_n when_o 10._o it_o be_v inflammability_n after_o it_o be_v reduce_v to_o a_o extract_n and_o dry_v put_v it_o out_o of_o all_o question_n and_o that_o 11._o a_o oil_n may_v be_v separate_v from_o the_o volatile_a salt_n though_o not_o without_o trouble_n because_o that_o as_o be_v requisite_a to_o complete_a it_o in_o the_o high_a degree_n seven_o the_o oily_a part_n and_o volatile_a salt_n be_v very_o intimate_o and_o strict_o combine_v as_o fair_o appear_v 1._o by_o the_o difficulty_n to_o separate_v they_o 2._o by_o the_o redness_n of_o the_o tincture_n as_o in_o blood_n etc._n etc._n for_o when_o oily_a or_o sulphureous_a particle_n be_v loose_a therein_o they_o make_v either_o a_o white_a colour_n as_o the_o rosin_n do_v in_o the_o drop_n that_o fall_v out_o of_o the_o incision_n in_o the_o head_n of_o the_o poppy_n which_o be_v milk_n white_a or_o leave_v the_o volatile_a spirit_n perspicuous_a as_o in_o a_o sort_n of_o artificial_a sal._n volatile-oleosum_a that_o be_v sell_v at_o the_o apothecary_n shop_n in_o london_n 3._o because_o it_o impart_v its_o tincture_n which_o depend_v upon_o both_o to_o all_o menstruum_n 4._o because_o it_o impart_v its_o virtue_n which_o depend_v upon_o both_o to_o all_o menstruum_n 5._o because_o it_o impart_v its_o specific_a smell_n which_o depend_v upon_o both_o to_o all_o menstruumt_v 6._o because_o it_o impart_v its_o specific_a hot_a and_o bite_a taste_n which_o depend_v upon_o both_o the_o oily_a and_o volatile_a particle_n to_o all_o menstruum_n 7._o because_o it_o will_v hold_v its_o virtue_n many_o year_n which_o it_o can_v not_o if_o the_o volatile_a salt_n and_o oily_a part_n be_v not_o very_o strict_o combine_v 8._o because_o that_o notwithstanding_o the_o digestion_n at_o stomach_n it_o have_v hold_v its_o specific_a virtue_n smell_v and_o taste_n after_o it_o have_v be_v in_o it_o 4_o 5_o 6_o 7_o 8_o 9_o 10_o 11_o 12_o 18_o or_o more_o hour_n as_o appear_v by_o its_o operate_n so_o long_o and_o afteward_n its_o be_v vomit_v up_o with_o the_o same_o taste_n and_o smell_v that_o it_o have_v at_o first_o than_o which_o there_o can_v be_v a_o great_a argument_n 9_o because_o it_o have_v be_v carry_v off_o by_o stool_n which_o have_v its_o specific_a smell_n after_o many_o hour_n remain_v in_o the_o stomach_n 10._o because_o its_o operation_n in_o general_n last_v long_o charas_fw-la mention_n one_o that_o it_o operate_v with_o for_o about_o 30_o hour_n and_o wedelius_n another_o who_o opium_n cause_v to_o vomit_v constant_o about_o 18_o hour_n after_o it_o be_v take_v 11._o because_o it_o have_v its_o effect_n upon_o the_o venereal_a membrane_n after_o it_o have_v pass_v the_o digestion_n at_o stomach_n the_o effect_n of_o the_o choler_n and_o succus_fw-la pancreatus_fw-la in_o the_o duodenum_fw-la be_v strain_v through_o the_o coat_n of_o the_o intestine_n into_o the_o lacteal_v and_o through_o the_o glandule_n of_o the_o mesentery_n mix_v and_o circulate_v with_o the_o blood_n etc._n etc._n 12._o because_o after_o all_o that_o it_o have_v its_o effect_n upon_o the_o skin_n by_o cause_v a_o itch_a therein_o 13._o because_o it_o not_o only_a cause_n acrimonious_a sweat_v but_o such_o as_o evident_o smell_v thereof_o
sect._n 7._o aph._n 6._o reddit_fw-la liberam_fw-la perspirationem_fw-la quam_fw-la animi_fw-la consolatio_fw-la aut_fw-la voluptas_fw-la &_o aph._n 19_o animi_fw-la consolatio_fw-la quacunque_fw-la de_fw-la causâ_fw-la aperit_fw-la meatus_fw-la &_o largam_fw-la perspirationem_fw-la facit_fw-la now_o you_o may_v perceive_v why_o opium_n and_o good_a cordial_n do_v moderate_a flux_n by_o stool_n even_o before_o they_o be_v out_o of_o the_o stomach_n because_o the_o pleasure_n there_o cause_v relax_n all_o part_n and_o thereby_o cause_v a_o expansion_n of_o the_o animal_n spirit_n the_o sense_n of_o the_o irritation_n be_v lose_v because_o the_o expand_v spirit_n can_v carry_v the_o impression_n smart_o to_o the_o sensitive_a soul_n which_o must_v be_v to_o cause_v a_o sense_n of_o irritation_n or_o grievous_a sensation_n by_o the_o same_o reason_n only_o warm_a trencher_n apply_v to_o the_o belly_n or_o sit_v upon_o a_o warm_a stool_n etc._n etc._n moderate_v a_o looseness_n because_o the_o pleasure_n of_o the_o warmth_n relax_n and_o so_o take_v away_o a_o sense_n of_o the_o irritation_n by_o the_o aforesaid_a expansion_n of_o the_o spirit_n 12._o i_o have_v just_a now_o show_v how_o it_o promote_v insensible_a perspiration_n viz._n by_o the_o relaxation_n open_v the_o pore_n and_o let_v out_o the_o fume_n which_o i_o need_v not_o have_v mention_v again_o but_o for_o order_n sake_n that_o all_o may_v thereby_o see_v that_o i_o evade_v the_o explication_n of_o no_o effect_n nor_o indeed_o need_v i_o for_o they_o be_v now_o obvious_a enough_o even_o without_o my_o explication_n to_o any_o sagacious_a person_n so_o that_o the_o plainness_n may_v give_v great_a cause_n to_o pass_v over_o some_o untouched_a than_o the_o difficulty_n but_o it_o be_v not_o sit_v that_o either_o shall_v cause_v any_o omission_n in_o such_o a_o mighty_a concern_v that_o be_v never_o explicate_v and_o scarce_o ever_o think_v possible_a 13._o opium_n prevent_v shivering_n in_o ague_n fit_n because_o that_o for_o the_o reason_n aforesaid_a it_o take_v away_o the_o sense_n of_o the_o irritate_v humour_n that_o cause_v they_o 14._o it_o prevent_v and_o cure_v cold_n by_o the_o relaxation_n that_o its_o pleasure_n cause_n whereby_o the_o pore_n be_v keep_v very_o open_a and_o perspiration_n as_o be_v show_v promote_v beside_o that_o it_o prevent_v the_o sensation_n of_o hinder_v it_o to_o constringe_v the_o pore_n by_o cause_v a_o grievous_a sensation_n 15._o it_o cause_v a_o large_a and_o slow_a pulse_n because_o of_o the_o relaxation_n that_o the_o intense_a and_o continual_a pleasure_n cause_n by_o which_o the_o artery_n be_v widen_v and_o the_o motion_n make_v slow_a 1._o because_o the_o animal_n spirit_n be_v weaken_v by_o the_o relaxation_n of_o their_o vessel_n and_o their_o expansion_n thereupon_o 2._o because_o the_o sense_n of_o irritation_n by_o which_o the_o heart_n be_v solicit_v to_o move_v fast_o be_v lose_v 16._o it_o cause_v dryness_n in_o the_o mouth_n as_o sleep_n do_v 1._o because_o the_o dilatation_n of_o the_o glandule_n by_o the_o relaxation_n detain_v and_o suspend_v the_o humour_n and_o 2._o because_o the_o sensation_n be_v lessen_v the_o membrane_n that_o include_v the_o salival_n glandule_n be_v not_o irritate_v to_o contraction_n to_o squeeze_v out_o the_o saliva_n or_o spital_n 3._o because_o the_o pulse_n be_v slow_a to_o cause_v a_o extrusion_n of_o the_o humour_n 17._o it_o have_v most_o effect_n in_o warm_a and_o moist_a wether_n because_o both_o warmth_n and_o moisture_n promote_v relaxation_n by_o which_o opium_n do_v upon_o the_o account_n of_o the_o pleasure_n it_o cause_v perform_v its_o effect_n 18._o it_o have_v more_o effect_n upon_o fine_a and_o lax_n texture_n for_o the_o same_o reason_n and_o because_o their_o sensation_n be_v more_o nice_a and_o affect_v more_o with_o please_a or_o grieve_v thing_n therefore_o it_o affect_v child_n and_o woman_n especial_o the_o nice_n and_o delicate_a more_o than_o man_n which_o may_v be_v the_o reason_n why_o woman_n do_v not_o use_v opium_n in_o the_o eastern_a country_n as_o much_o as_o men._n 19_o it_o cause_v a_o efflorescence_n or_o redness_n of_o the_o skin_n as_o sleep_n or_o wine_n do_v because_o the_o skin_n be_v relax_v admit_v the_o blood_n to_o come_v into_o it_o very_o free_o as_o cold_a fear_v etc._n etc._n contract_v the_o part_n of_o the_o skin_n repel_v it_o or_o squeeze_v it_o out_o or_o back_o again_o thus_o person_n that_o drink_v much_o get_v red_a nose_n by_o frequent_a relaxation_n of_o the_o skin_n which_o widen_v the_o road_n of_o the_o blood_n more_o and_o more_o hence_o it_o be_v that_o the_o bag_n at_o a_o turky-cock_n neck_n be_v red_a when_o he_o be_v please_v and_o soon_o pale_a again_o when_o displease_v 20._o it_o affect_v the_o genus_fw-la nervosum_fw-la or_o animal_n spirit_n which_o be_v a_o common_a observation_n more_o than_o the_o blood_n because_o it_o operate_v by_o affect_v sensation_n wherein_o the_o nerve_n and_o membrane_n be_v most_o concern_v and_o not_o by_o alter_v the_o blood_n to_o which_o it_o bear_v no_o proportion_n to_o cause_v any_o remarkable_a effect_n note_v how_o plain_o this_o concession_n of_o all_o author_n confirm_v what_o i_o say_v viz._n that_o it_o do_v not_o operate_v as_o a_o alterative_a of_o the_o blood_n etc._n etc._n but_o by_o affect_v sensation_n as_o i_o have_v prove_v 21._o it_o increase_v seed_n in_o some_o measure_n because_o it_o administer_v a_o sal-volatile-oleosum_a of_o the_o same_o nature_n with_o it_o and_o by_o its_o titillation_n solicit_v and_o invite_v the_o send_n of_o its_o matter_n that_o way_n as_o be_v observable_a in_o such_o as_o use_v much_o titillation_n but_o to_o speak_v plain_o and_o mechanical_o i_o think_v that_o this_o main_o happen_v because_o of_o the_o relaxation_n of_o the_o part_n admit_v as_o be_v say_v of_o the_o efflorescence_n of_o the_o skin_n by_o relaxation_n the_o blood_n or_o material_n of_o seed_n more_o free_o into_o the_o testicle_n and_o all_o the_o seminary_n vessel_n especial_o be_v that_o the_o titillation_n cause_v a_o ostener_o empty_v of_o the_o same_o in_o order_n to_o receive_v those_o material_n with_o less_o opposition_n for_o quod_fw-la intus_fw-la est_fw-la prohibet_fw-la alienum_fw-la that_o be_v what_o be_v within_o hinder_v the_o entrance_n of_o other_o matter_n nothing_o can_v receive_v more_o than_o what_o it_o can_v contain_v but_o what_o be_v often_o empty_v can_v successive_o receive_v much_o 22._o it_o cause_v a_o great_a promptitude_n to_o venery_n erection_n etc._n etc._n especial_o if_o the_o do_v be_v large_a than_o ordinary_a because_o be_v of_o the_o same_o principle_n with_o animal_n seed_n and_o in_o all_o probability_n somewhat_o more_o titillate_v and_o of_o like_a principle_n though_o more_o gentle_a than_o cantharides_n it_o must_v high_o titillate_v those_o part_n and_o consequent_o cause_v a_o great_a promptitude_n to_o venery_n chap._n xviii_o the_o explication_n of_o the_o frequent_a though_o not_o constant_a effect_n of_o opium_n in_o a_o moderate_a do_v 1._o it_o cause_v sleep_n because_o it_o high_o dispose_v thereto_o by_o the_o relaxation_n that_o its_o pleasure_n cause_n thus_o music_n agreeable_a frication_n and_o many_o other_o pleasure_n nay_o all_o that_o be_v consistent_a with_o lie_v or_o sit_v still_o and_o silent_a incline_v we_o to_o sleep_n but_o none_o can_v compare_v with_o the_o sweet_a continual_a and_o transcendent_a pleasure_n of_o opium_n that_o we_o carry_v along_o with_o we_o for_o many_o hour_n whereas_o other_o pleasure_n be_v either_o remiss_a or_o interrupt_v or_o transient_a in_o their_o nature_n for_o continuance_n in_o gentle_a pleasure_n as_o the_o fall_n of_o water_n whistle_v of_o wind_n effect_n much_o towards_o sleep_n so_o intenseness_n do_v also_o though_o momentary_a as_o that_o of_o venus_n how_o much_o than_o must_v a_o continual_a and_o intense_a pleasure_n cause_n it_o especial_o when_o rest_n silence_n etc._n etc._n be_v add_v thereto_o note_v that_o sleep_n be_v so_o far_o from_o be_v a_o property_n of_o opium_n that_o it_o do_v not_o belong_v to_o it_o omni_n soli_fw-la or_o semper_fw-la yet_o people_n have_v general_o look_v upon_o sleep_n as_o such_o which_o cause_v many_o error_n 2._o it_o cause_v pleasant_a dream_n because_o the_o very_a sleep_n be_v cause_v and_o continue_v by_o pleasure_n when_o it_o be_v by_o opium_n which_o pleasure_n be_v all_o the_o time_n we_o sleep_v within_o we_o must_v needs_o suggest_v pleasant_a dream_n or_o none_o for_o how_o can_v sad_a and_o melancholy_a dream_n seize_v one_o that_o be_v in_o a_o gay_a and_o pleasant_a condition_n as_o far_o as_o one_o in_o sleep_n be_v capable_a thereof_o 3._o it_o stop_v vomit_v 1._o as_o it_o do_v other_o flux_n by_o take_v away_o the_o sense_n of_o irritation_n 2._o by_o high_o please_v and_o thereby_o quiet_v and_o compose_v the_o commotion_n of_o the_o stomach_n 3._o by_o relax_v it_o which_o oppose_v the_o
contraction_n by_o which_o vomit_v be_v perform_v 4._o it_o still_v hiccough_n for_o the_o same_o reason_n 5._o it_o cause_v convulsion_n and_o contraction_n to_o cease_v 1._o because_o it_o induce_v a_o relaxation_n which_o take_v they_o off_o 2._o by_o take_v off_o the_o sense_n which_o the_o irritate_v cause_n 3._o by_o compose_v the_o spirit_n 6._o it_o cause_v the_o meat_n to_o stay_v long_o at_o stomach_n as_o sleep_n do_v 1._o by_o relax_v the_o stomach_n so_o that_o it_o be_v not_o subject_a to_o contract_v to_o send_v it_o out_o 2._o by_o still_v all_o motion_n whereby_o the_o stomach_n grow_v proportionable_o unactive_a 3._o because_o the_o relaxation_n oppose_v the_o contraction_n by_o which_o the_o menstruum_fw-la be_v send_v into_o the_o stomach_n or_o the_o saliva_n into_o the_o mouth_n both_o which_o be_v therefore_o much_o want_v in_o sleep_n for_o the_o like_a reason_n as_o have_v be_v show_v 7._o it_o moderate_v and_o prevent_v hunger_n 1._o because_o as_o be_v say_v the_o menstruum_fw-la be_v not_o so_o plentiful_o send_v or_o squeeze_a into_o the_o relaxed_a stomach_n 2._o because_o it_o take_v away_o the_o sense_n of_o hunger_n 3._o because_o it_o leave_v the_o meat_n to_o stay_v too_o long_o at_o stomach_n by_o reason_n that_o it_o be_v relax_v more_o insensible_a and_o proportionable_o languid_a in_o motion_n as_o in_o sleep_n 8._o it_o cause_v sweat_v when_o the_o body_n be_v full_a of_o moisture_n as_o sleep_n do_v by_o relax_v and_o thereby_o open_v the_o pore_n and_o not_o as_o people_n common_o talk_v by_o attenuate_v and_o the_o like_a for_o a_o grain_n of_o opium_n bear_v no_o proportion_n to_o the_o blood_n and_o humour_n that_o it_o cause_v it_o mere_o as_o sleep_n do_v be_v manifest_a not_o only_o because_o it_o bear_v not_o a_o due_a proportion_n to_o the_o work_n as_o a_o alterative_a but_o because_o man_n do_v not_o sweat_v in_o that_o case_n as_o in_o sleep_n without_o much_o moisture_n in_o the_o body_n whereas_o much_o will_v not_o be_v attenuate_v as_o soon_o as_o less_o therefore_o it_o be_v only_o a_o exudation_n of_o the_o humour_n upon_o a_o plenty_n thereof_o and_o open_v of_o the_o pore_n sanctorius_n sect._n 1_o aph._n 22._o invisibilis_fw-la perspiratio_fw-la fit_a visibilis_fw-la quando_fw-la nutrimentum_fw-la est_fw-la nimium_fw-la that_o be_v invisible_a perspiration_n become_v visible_a sweat_n when_o nourishment_n or_o moisture_n be_v too_o much_o which_o exact_o agree_v with_o that_o of_o hypocrates_n cite_v in_o chap._n 13._o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d etc._n etc._n 9_o it_o cause_v the_o menses_fw-la to_o flow_v when_o nothing_o be_v want_v but_o the_o open_n or_o relax_v of_o the_o viae_fw-la or_o pore_n they_o issue_v out_o at_o as_o when_o they_o be_v natural_o too_o narrow_a and_o close_a as_o upon_o the_o first_o tendency_n to_o they_o in_o young_a girl_n or_o when_o stop_v by_o reason_n of_o any_o undue_a contraction_n thereof_o as_o by_o pain_n cold_a sorrow_n or_o other_o grievous_a passion_n all_o which_o do_v close_o the_o pore_n beside_o it_o do_v irritate_fw-la those_o very_a sensile_a venereal_a part_n to_o erection_n and_o i_o have_v reason_n to_o think_v that_o it_o do_v by_o a_o general_a relaxation_n cause_n a_o increase_n of_o blood_n as_o it_o do_v of_o the_o breast_n milk_n etc._n etc._n cause_v as_o it_o be_v a_o artificial_a puberty_n or_o at_o least_o much_o promote_a the_o natural_a and_o therefore_o be_v of_o excellent_a use_n in_o this_o case_n in_o judicious_a hand_n though_o little_a thought_n of_o in_o practice_n obj._n here_o i_o may_v be_v sure_a of_o a_o objection_n that_o it_o stop_v all_o flux_n but_o sweat_v or_o perspiration_n ans._n it_o be_v as_o false_a as_o it_o be_v a_o common_a say_n if_o they_o do_v not_o mean_v only_o such_o flux_n as_o proceed_v from_o grievous_a sensation_n and_o contraction_n thereupon_o for_o how_o can_v that_o which_o relax_n all_o part_n stop_v any_o flux_n that_o depend_v upon_o relaxation_n as_o stillicidium_fw-la urinae_fw-la by_o relaxation_n of_o the_o sphincter_n of_o the_o â—ladder_n involuntary_a flux_n per_fw-la anum_fw-la by_o the_o 〈◊〉_d of_o its_o sphincter_n and_o such_o like_a so_o do_v i_o speak_v of_o a_o flux_n that_o may_v often_o depend_v upon_o relaxation_n as_o i_o have_v show_v obj._n but_o it_o may_v be_v object_v that_o it_o particular_o stanche_n blood_n how_o then_o shall_v it_o promote_v the_o menses_fw-la ans._n experience_n tell_v i_o it_o do_v and_o reason_n confirm_v it_o it_o stanche_n blood_n by_o compose_v the_o fury_n of_o its_o motion_n but_o that_o do_v not_o hinder_v but_o it_o may_v relax_v the_o pore_n for_o sweat_n menses_fw-la lochia_n etc._n etc._n to_o pass_v and_o why_o not_o for_o the_o menses_fw-la and_o lochia_n as_o well_o as_o sweat_v by_o open_v the_o pore_n i_o will_v fain_o know_v consider_v also_o the_o titillation_n that_o it_o cause_n upon_o those_o venereal_a part_n which_o may_v very_o much_o solicit_v their_o motion_n 10._o it_o cause_v the_o lochia_n to_o flow_v for_o the_o same_o reason_n that_o it_o do_v the_o menses_fw-la this_o i_o have_v great_a experience_n in_o note_v that_o the_o menses_fw-la lochia_n and_o perspiration_n be_v natural_a evacuation_n that_o have_v pore_n design_v for_o they_o by_o nature_n the_o open_n of_o which_o by_o relaxation_n must_v make_v way_n for_o they_o suppose_v when_o the_o blood_n flow_v so_o much_o into_o the_o skin_n as_o to_o cause_v a_o efflorescence_n by_o the_o relaxation_n thereof_o after_o opium_n be_v take_v that_o there_o be_v pore_n to_o carry_v out_o blood_n as_o there_o be_v for_o sweat_n why_o shall_v not_o one_o flow_v as_o well_o as_o the_o other_o but_o there_o be_v such_o pore_n for_o the_o menses_fw-la and_o lochia_n and_o large_a one_o too_o and_o therefore_o it_o must_v promote_v they_o and_o why_o shall_v not_o relaxation_n do_v it_o as_o well_o as_o contraction_n by_o cold_a terror_n grief_n etc._n etc._n stop_v they_o for_o the_o effect_n of_o contrary_n be_v contrary_a 11._o it_o cause_v the_o stone_n to_o pass_v 1._o because_o it_o reâ—_n and_o so_o widen_v the_o passage_n 2._o because_o it_o 〈◊〉_d move_v with_o little_a or_o no_o pain_n which_o contract_v the_o part_n and_o so_o hinder_v its_o passage_n therefore_o the_o use_n of_o opium_n with_o some_o other_o help_v be_v the_o great_a mean_n that_o can_v be_v or_o ever_o will_v be_v for_o the_o stone_n till_o the_o dissolution_n of_o it_o be_v find_v out_o not_o only_o to_o give_v ease_n in_o the_o case_n of_o the_o stone_n but_o to_o cause_v it_o to_o pass_v for_o both_o which_o purpose_v it_o excel_v all_o thing_n and_o do_v both_o at_o once_o 12._o it_o cause_v the_o delivery_n of_o woman_n by_o relax_v the_o neck_n of_o the_o womb_n as_o it_o do_v that_o of_o the_o bladder_n to_o deliver_v person_n of_o the_o stone_n but_o in_o the_o delivery_n of_o woman_n it_o be_v not_o to_o be_v use_v but_o in_o particular_a case_n and_o by_o a_o very_a skilful_a hand_n 1._o because_o it_o be_v apt_a to_o take_v off_o all_o the_o woman_n pain_n and_o throw_v and_o so_o quite_o disappoint_v the_o delivery_n for_o a_o day_n 2_o 3_o 4_o or_o more_o sometime_o 2._o because_o it_o cause_v a_o great_a relaxation_n the_o part_n after_o delivery_n will_v be_v very_o unapt_a to_o close_v and_o contract_v due_o as_o they_o shall_v in_o such_o case_n otherwise_o several_a inconvenience_n may_v ensue_v 3._o it_o may_v be_v pernicious_a upon_o the_o account_n of_o the_o evacuation_n of_o blood_n that_o then_o happen_v but_o these_o thing_n belong_v more_o proper_o to_o the_o use_v of_o opium_n in_o cure_n 13._o it_o cause_v deadness_n of_o the_o eye_n as_o in_o drunkeness_n etc._n etc._n because_o the_o cornea_n be_v relax_v so_o that_o the_o humour_n do_v not_o fill_v it_o up_o to_o a_o tense_n rotundity_n as_o when_o it_o be_v more_o contract_v 14._o it_o cause_v the_o pupilla_fw-la to_o dilate_v because_o of_o the_o same_o relaxation_n 15._o it_o cause_v a_o growth_n of_o the_o breast_n penis_n and_o increase_v of_o milk_n by_o reason_n of_o the_o same_o relaxation_n as_o the_o pleasure_n of_o the_o semen_n upon_o puberty_n do_v or_o as_o emollient_n and_o relaxer_n apply_v to_o the_o breast_n increase_v milk_n etc._n etc._n by_o make_v more_o room_n for_o it_o etc._n etc._n 16._o it_o cause_v venereal_a dream_n because_o of_o the_o titillation_n of_o the_o venereal_a membrane_n that_o it_o cause_n 17._o it_o cause_v nocturnal_a pollution_n for_o the_o same_o reason_n and_o because_o it_o relax_n the_o part_n 18._o it_o cause_v itch_n in_o the_o skin_n because_o of_o its_o titillation_n by_o its_o volatile_a salt_n 19_o it_o cause_v much_o urine_n as_o cantbaride_n bee_n pismire_n millepedes_n etc._n etc._n do_v by_o its_o volatile_a salt_n which_o titillate_n and_o irritate_v those_o
and_o frequent_a erection_n be_v and_o must_v be_v from_o the_o same_o cause_n 17._o nocturnal_a pollution_n be_v necessary_a consequence_n of_o the_o relaxation_n and_o the_o titillation_n cause_v by_o those_o volatile_a salt_n as_o be_v say_v chap._n xxiii_o the_o explication_n of_o the_o effect_n of_o leave_v off_o opium_n after_o a_o long_a and_o lavish_a use_v thereof_o i._o great_a and_o even_o intolerable_a distress_n anxiety_n and_o depression_n of_o spirit_n do_v happen_v 1._o because_o the_o sensitive_a soul_n who_o be_v so_o much_o comfort_v divert_v and_o support_v by_o the_o habitual_a and_o dear_o belove_a pleasure_n that_o opium_n cause_n be_v sudden_o deprive_v thereof_o by_o which_o it_o be_v main_o sustain_v be_v exceed_o disappoint_v and_o cast_v down_o 2._o because_o he_o now_o labour_v under_o the_o sore_a burden_n of_o the_o three_o contraction_n so_o that_o every_o thing_n seem_v and_o be_v real_o more_o grievous_a â—o_o he_o for_o now_o it_o act_v as_o one_o in_o pain_n or_o grief_n and_o every_o thing_n affect_v he_o more_o smart_o proportionable_a to_o the_o compression_n cause_v thereby_o of_o the_o animal_n spirit_n unless_o he_o return_v to_o the_o pleasure_n of_o opium_n which_o elevate_v it_o again_o or_o use_v generous_a wine_n as_o its_o substitute_n though_o it_o do_v not_o equal_v it_o either_o in_o the_o intenseness_n or_o duration_n of_o the_o pleasure_n unless_o repeat_v as_o i_o have_v some_o where_o direct_v once_o in_o half_a a_o hour_n or_o a_o hour_n in_o a_o moderate_a manner_n which_o cause_v a_o continuance_n of_o the_o pleasure_n though_o it_o can_v equal_v the_o intenseness_n of_o that_o of_o opium_n which_o therefore_o have_v the_o great_a effect_n ii_o a_o return_n of_o all_o disease_n pain_n and_o disaster_n must_v happen_v general_o because_o the_o opium_n take_v they_o off_o by_o a_o bare_a diversion_n of_o the_o sense_n thereof_o by_o pleasure_n iii_o dangerous_a looseness_n happen_v sometime_o because_o the_o sensation_n grow_v more_o grievous_a for_o as_o the_o pleasant_a sensation_n cause_v by_o opium_n take_v away_o the_o perception_n of_o the_o irritation_n of_o humour_n so_o the_o grievance_n of_o lose_v that_o pleasure_n cause_v contraction_n make_v all_o sensation_n smart_a and_o consequent_o more_o irritate_v so_o that_o the_o humour_n have_v thereby_o more_o of_o the_o effect_n of_o purger_n which_o operate_v as_o all_o agree_v by_o irritation_n beside_o that_o the_o humour_n before_o detain_v and_o suspend_v by_o relaxation_n as_o in_o sleep_n be_v now_o therefore_o pour_v down_o in_o great_a quantity_n by_o the_o advance_a contraction_n squeese_v they_o out_o as_o the_o return_n of_o the_o vigilative_a contraction_n after_o sleep_n cause_n man_n to_o be_v more_o apt_a to_o go_v to_o stool_n upon_o awake_v or_o get_v up_o in_o the_o morning_n which_o may_v be_v well_o compare_v in_o some_o measure_n to_o purge_v after_o leave_v off_o the_o use_n of_o opium_n since_o it_o relax_n as_o sleep_n do_v and_o that_o for_o a_o much_o long_a time_n by_o a_o continue_a use_n thereof_o iv_o death_n common_o follow_v for_o all_o the_o reason_n aforesaid_a especial_o the_o great_a and_o intolerable_a distress_n of_o soul_n that_o they_o be_v under_o unless_o opium_n be_v use_v which_o soon_o set_v they_o right_o or_o wine_n its_o substitute_n so_o frequent_o use_v as_o to_o continue_v its_o cordial_a pleasure_n at_o stomach_n nothing_o now_o remain_v but_o to_o take_v a_o short_a review_n to_o see_v whether_o i_o have_v explain_v all_o the_o amaze_a contradiction_n that_o seem_v to_o be_v in_o the_o effect_n of_o opium_n for_o though_o it_o be_v real_o do_v yet_o may_v it_o not_o so_o well_o appear_v as_o when_o set_v one_o against_o the_o other_o it_o will_v be_v tautology_n to_o repeat_v all_o the_o reason_n therefore_o i_o shall_v only_o mention_v they_o in_o the_o close_a order_n i_o at_o first_o enumerate_v they_o that_o you_o may_v see_v that_o they_o be_v all_o explicate_v in_o the_o former_a discourse_n you_o may_v well_o remember_v that_o i_o have_v show_v 1._o how_o it_o cause_v sleep_v and_o watch_v in_o divers_a person_n 2._o how_o it_o cause_v and_o prevent_v sweat_n 3._o how_o it_o relax_n and_o stop_n looseness_n even_o by_o relax_v 4._o how_o it_o stop_v flux_n and_o promote_v sweat_v and_o perspiration_n 5._o how_o it_o stupefy_v the_o sense_n of_o feel_v yet_o irritate_v it_o 6._o how_o it_o cause_v stupidity_n if_o you_o sit_v or_o lie_v still_o otherwise_o promptitude_n in_o business_n 7._o how_o it_o cause_v cloudiness_n and_o serenity_n that_o if_o one_o lie_v still_o and_o doze_n this_o if_o he_o keep_v in_o action_n that_o by_o a_o excessive_a and_o lavish_a use_v thereof_o which_o cause_v moapishness_n this_o by_o a_o temperate_a occasional_a take_v thereof_o especial_o in_o the_o morning_n upon_o journey_n etc._n etc._n 8._o how_o it_o excite_v the_o spirit_n yet_o quiet_v and_o compose_v they_o in_o hysterick_n fit_v diary_n fever_n from_o pain_n commotion_n etc._n etc._n 9_o how_o that_o it_o be_v very_o hot_a and_o take_v of_o fever_n 10._o how_o though_o it_o be_v hot_a and_o bitter_a yet_o it_o lessen_v appetite_n and_o hunger_n which_o be_v a_o grievous_a sensation_n by_o cause_v a_o pleasant_a one_o 11._o how_o it_o sometime_o stop_v urine_n by_o relax_v the_o bladder_n suspending_a humour_n etc._n etc._n and_o promote_v it_o by_o its_o tickle_a volatile_a salt_n as_o cantharides_n bee_n aunt_n etc._n etc._n do_v 12._o how_o it_o relax_n and_o thereby_o weaken_v as_o in_o sleep_n etc._n etc._n yet_o enable_v to_o perform_v labour_n journey_n etc._n etc._n with_o great_a euphory_n by_o divertive_a pleasure_n 13._o how_o it_o cause_v and_o prevent_v abortion_n that_o by_o over-relaxing_a this_o by_o allay_a pain_n terror_n etc._n etc._n that_o may_v cause_v it_o 14._o how_o it_o stop_v vomit_v by_o take_v off_o irritation_n etc._n etc._n and_o cause_v it_o by_o the_o adherence_n of_o its_o indigestible_a and_o viscid_a rosin_n 15._o how_o it_o stop_v purge_v and_o sometime_o cause_v it_o by_o the_o dissolution_n of_o its_o rosin_n by_o a_o strong_a digestion_n fix_a salt_n etc._n etc._n when_o its_o quantity_n be_v considerable_a which_o make_v it_o happen_v but_o rare_o 16._o how_o though_o acrimonious_a it_o take_v away_o the_o sense_n of_o acrimony_n 17._o how_o it_o cause_v madness_n and_o cure_v it_o by_o compose_v the_o spirit_n etc._n etc._n 18._o how_o it_o cause_v palsy_n by_o relax_v the_o part_n and_o make_v they_o susceptible_a of_o humour_n cause_v ill_a digestion_n etc._n etc._n and_o may_v cure_v they_o as_o dr._n willis_n give_v a_o instance_n by_o open_v the_o pore_n 19_o how_o it_o cause_v palsy_n and_o cure_n stupor_n etc._n etc._n that_o proceed_v from_o cold_a and_o contract_n cause_n 20._o how_o it_o cause_v dryness_n in_o the_o mouth_n yet_o by_o take_v off_o fever_n often_o cure_v it_o 21._o how_o it_o take_v off_o hiccough_n and_o cause_v they_o as_o it_o do_v vomit_v and_o for_o the_o same_o cause_n 22._o how_o it_o stanch_v blood_n by_o quiet_v its_o motion_n yet_o promote_v the_o menses_fw-la and_o lochia_n by_o relax_v open_v and_o widen_v the_o vessel_n and_o pore_n 23._o how_o it_o stop_v critical_a motion_n that_o depend_v upon_o irritation_n and_o contraction_n and_o promote_v such_o as_o depend_v upon_o open_v the_o pore_n 24._o how_o it_o revive_v people_n that_o be_v at_o the_o point_n of_o death_n for_o want_n of_o opium_n or_o by_o violent_a contraction_n and_o convulsion_n and_o be_v fatal_a to_o other_o weak_a person_n 25._o how_o it_o cause_v convulsion_n by_o its_o grieve_v rosin_n and_o cure_v they_o by_o quiet_v and_o compose_v the_o spirit_n by_o please_v they_o 26._o how_o it_o cause_v contraction_n by_o the_o grievous_a sensation_n that_o its_o rosin_n cause_n and_o relaxation_n by_o the_o pleasant_a sensation_n that_o its_o salvolatile_a oleosum_fw-la cause_n by_o that_o it_o cause_v many_o ill_a effect_n not_o here_o name_v and_o by_o this_o it_o cure_v they_o for_o how_o can_v such_o contrary_a cause_n according_a as_o one_o or_o the_o other_o prevail_v not_o cause_v contrary_a and_o seem_o contradictory_n effect_n at_o divers_a time_n and_o in_o divers_a person_n 27._o how_o it_o relax_n yet_o cause_v the_o tension_n rigidity_n and_o erection_n of_o the_o penis_n priapism_n etc._n etc._n by_o its_o titillation_n thus_o have_v you_o all_o even_o the_o most_o mysterious_a and_o seem_o contradictory_n effect_n of_o opium_n explain_v and_o reconcile_v and_o that_o so_o easy_o that_o if_o there_o be_v no_o other_o proof_n of_o the_o truth_n of_o my_o foundation_n it_o be_v sufficient_a to_o convince_v any_o man_n of_o its_o validity_n consider_v the_o vastness_n of_o the_o number_n and_o perplexity_n of_o the_o nature_n of_o those_o effect_n that_o be_v all_o with_o such_o facility_n explain_v be_v able_a even_o
proclaim_v their_o ignorance_n and_o glory_v in_o their_o great_a shame_n and_o disgrace_n of_o mankind_n that_o humane_a species_n shall_v have_v any_o such_o unthinking_a brute_n in_o it_o iv_o we_o must_v not_o use_v acid_n in_o the_o preparation_n thereof_o 1._o because_o be_v in_o their_o nature_n opposite_a to_o volatile_a salt_n it_o can_v be_v do_v without_o injury_n to_o the_o sal-volatile-oleosum_a of_o opium_n 2._o because_o they_o can_v so_o well_o agree_v with_o the_o oily_a part_n of_o it_o yet_o be_v they_o not_o so_o much_o to_o be_v blame_v as_o extract_n make_v in_o spirit_n of_o wine_n or_o sulphureous_a menstruum_n because_o acid_a menstruum_n leave_v the_o rosin_n behind_o they_o untouched_a or_o not_o extract_v v._o a_o salino-volatile_a menstruum_fw-la as_o spirit_n of_o sal_fw-la ammoniac_a of_o urine_n etc._n etc._n be_v not_o so_o proper_a 1._o it_o may_v render_v the_o sal-volatile-oleosum_a of_o opium_n too_o acrimonious_a 2._o because_o by_o its_o volatility_n acrimony_n etc._n etc._n it_o may_v cause_v too_o great_a a_o stir_n in_o the_o blood_n etc._n etc._n and_o so_o oppose_v or_o hinder_v sleep_n which_o be_v one_o of_o the_o most_o happy_a and_o useful_a effect_n of_o opium_n or_o it_o be_v sal-volatile-oleosum_a 3._o because_o it_o may_v have_v undue_a effect_n by_o alter_v its_o general_a disposition_n nay_o vi_o we_o be_v not_o to_o use_v a_o lixivial_a menstruum_fw-la though_o so_o much_o cry_v up_o 1._o because_o it_o extract_v the_o resinous_a part_n which_o experto_fw-la crede_fw-la roberto_n i_o have_v find_v to_o be_v pernicious_a upon_o that_o account_n like_o extract_n in_o spirit_n of_o wine_n unless_o great_a care_n be_v take_v to_o separate_v those_o part_n which_o be_v not_o easy_o do_v by_o filtration_n etc._n etc._n 2._o because_o be_v very_o apt_a to_o join_v with_o the_o oily_a part_n and_o quite_o to_o destroy_v their_o nature_n by_o convert_v it_o into_o a_o kind_n of_o sapo_n it_o may_v deal_v so_o with_o some_o of_o the_o oily_a part_n of_o the_o sal-volatile-oleosum_a of_o opium_n 3._o because_o there_o be_v no_o need_n to_o run_v any_o of_o these_o hazard_n since_o the_o sal-volatile-oleosum_a may_v be_v as_o i_o shall_v show_v easy_o extract_v in_o its_o purity_n without_o those_o trouble_n and_o danger_n 4._o because_o any_o tincture_n make_v thus_o be_v apt_a to_o let_v go_v the_o rosin_n at_o stomach_n if_o it_o be_v dilute_v with_o aqueous_a moisture_n take_v before_o with_o it_o or_o after_o it_o which_o so_o be_v let_v go_v coalesces_fw-la and_o do_v mischief_n vii_o the_o use_n of_o fire_n any_o way_n beside_o that_o of_o its_o torrefaction_n be_v much_o to_o be_v suspect_v 1._o because_o the_o sal-volatile-oleosum_a may_v be_v in_o some_o measure_n thereby_o evaporate_v or_o 2._o an_fw-mi empyreum_fw-la contract_v and_o 3._o the_o rosin_n as_o be_v say_v of_o its_o torrefaction_n grow_v the_o more_o in_o proportion_n if_o any_o of_o the_o sal-volatile-oleosum_a or_o but_o the_o phlegm_n be_v by_o that_o mean_n evaporate_v and_o the_o remainder_n keep_v for_o use_v and_o particular_o viii_o the_o distillation_n thereof_o may_v cause_v mighty_a alteration_n in_o its_o property_n strength_n etc._n etc._n we_o must_v therefore_o avoid_v all_o these_o way_n of_o prepare_v it_o and_o yet_o must_v we_o 1._o separate_a the_o sal-volatile-oleosum_a of_o opium_n from_o all_o its_o rosin_n earth_n filth_n and_o dross_n 2._o no_o way_n weaken_v it_o alter_v it_o or_o add_v new_a quality_n thereto_o but_o preserve_v this_o most_o noble_a and_o inestimable_a medicament_n in_o its_o purity_n and_o sincerity_n to_o this_o end_n rain_n water_v distil_v use_v cold_a answer_v all_o intent_n for_o 1._o it_o ready_o imbibe_v the_o sal-volatile-oleosum_a of_o opium_n without_o fire_n heat_v lixivial_a salt_n as_o salt_n of_o tartar_n etc._n etc._n 2._o it_o imbibe_v none_o of_o the_o rosin_n of_o the_o opium_n but_o let_v it_o all_o subside_n together_o with_o the_o earthy_a and_o drossy_a part_n separate_v the_o light_a filth_n if_o there_o be_v any_o to_o the_o surface_n 3._o it_o no_o way_n weaken_v alter_v or_o add_v any_o new_a quality_n to_o the_o sal-volatile-oleosum_a 4._o whatever_o cold_a water_n dissolve_v which_o be_v the_o general_n drink_v or_o menstruum_fw-la appoint_v by_o the_o alwise_a creater_n for_o the_o dissolution_n of_o all_o thing_n take_v into_o the_o stomach_n of_o animal_n be_v easy_o dissolve_v at_o stomach_n by_o its_o more_o powerful_a and_o agreeable_a menstruum_fw-la and_o not_o only_o so_o but_z 5._o water_n itself_o be_v a_o mighty_a stomachick_n and_o causer_n of_o digestion_n as_o hypocrates_n positive_o declare_v l._n 6._o epidem_fw-la sect._n 4._o but_o there_o be_v no_o need_n of_o quote_v hypocrates_n in_o so_o notorious_a a_o thing_n daily_a experience_n tell_v we_o the_o same_o do_v not_o all_o animal_n by_o its_o help_n digest_v their_o food_n do_v not_o all_o mineral_n water_n scarce_o any_o except_v create_v a_o appetite_n and_o cause_n digestion_n even_o when_o no_o such_o effect_n can_v be_v attribute_v to_o the_o mineral_n they_o contain_v than_o which_o they_o do_v also_o as_o may_v be_v very_o easy_o prove_v more_o good_a general_o speak_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d for_o which_o and_o many_o more_o reason_n it_o be_v great_a neglect_n and_o folly_n that_o it_o be_v not_o more_o use_v for_o extract_n etc._n etc._n for_o then_o they_o ready_o dissolve_v at_o stomach_n and_o thereby_o 〈◊〉_d and_o speedy_o take_v effect_n give_v it_o the_o least_o 〈◊〉_d and_o disturbance_n that_o may_v be_v as_o be_v experimental_o find_v in_o that_o of_o aloe_n scammony_n briony_n 〈◊〉_d agariâ—_n 〈◊〉_d coloquintida_n sena_n and_o what_o not_o unless_o the_o virtue_n lie_v in_o the_o resinous_a parâ—s_n for_o then_o sulphureous_a or_o lixivial_a menstruum_n be_v convenient_a how_o inconvenient_a be_v they_o then_o when_o the_o evil_a or_o mischief_n lie_v therein_o as_o in_o our_o case_n 6._o it_o be_v not_o to_o be_v doubt_v but_o water_n general_o imbibe_v what_o be_v best_a and_o most_o agreeable_a to_o our_o body_n it_o be_v the_o general_n menstruum_fw-la appoint_v by_o wisdom_n itself_o for_o that_o use_v and_o to_o be_v the_o vehicle_n of_o what_o be_v best_a in_o all_o our_o food_n etc._n etc._n to_o the_o blood_n however_o there_o can_v be_v no_o doubt_n of_o what_o main_o concern_v we_o at_o present_a its_o most_o ready_a dissolve_v our_o panacea_fw-la in_o the_o stomach_n that_o do_v it_o out_o of_o it_o when_o cold_a without_o the_o convenient_a digestive_a heat_n and_o powerful_a menstruum_fw-la that_o it_o find_v there_o therefore_o take_v of_o distil_a rain-water_n 24_o ounce_n of_o choice_a opium_n slice_v thin_a 8_o ounce_n put_v they_o together_o in_o a_o strong_a glass_n vessel_n of_o bottle-metal_n that_o contain_v about_o 3_o piâ—ts_n let_v it_o be_v of_o a_o tall_a figure_n with_o a_o mouth_n that_o convenient_o receive_v a_o cork_n a_o large_a glass_n bottle_n may_v serve_v the_o turn_n cork_n it_o so_o as_o the_o cork_n may_v be_v easy_o take_v out_o shake_v it_o 3_o or_o 4_o time_n a_o day_n for_o 6_o day_n and_o keep_a it_o in_o a_o place_n free_a from_o frost_n or_o any_o very_a sensible_a degree_n of_o heat_n which_o be_v perform_v lie_v the_o vessel_n side-long_a for_o 24_o hour_n long_o and_o afterward_o decant_v and_o filter_n your_o tincture_n which_o will_v be_v of_o a_o ruby_n colour_n and_o put_v it_o into_o a_o glass_n bottle_n of_o such_o a_o bigness_n as_o that_o it_o may_v fill_v it_o within_o a_o small_a matter_n of_o the_o cork_n and_o so_o let_v it_o stand_v for_o 3_o or_o 4_o day_n then_o poâ—r_v off_o some_o of_o the_o surface_n of_o it_o and_o instead_o thereof_o put_v sweet_a oil_n thereon_o let_v the_o vessel_n have_v a_o convenient_a dust_n or_o pipe_n in_o the_o side_n thereof_o to_o empty_v it_o out_o upon_o occasion_n this_o i_o call_v the_o liquid_a panacea_fw-la of_o opium_n to_o the_o faeces_fw-la add_v a_o pint_n of_o cold_a distil_a water_n shake_v the_o vessel_n as_o before_o 3_o or_o 4_o time_n in_o the_o day_n let_v it_o stand_v on_o it_o 24_o hour_n and_o in_o the_o morning_n decant_v it_o into_o another_o vessel_n repeat_v the_o same_o quantity_n of_o distil_a rain-water_n till_o the_o opium_n no_o long_o tinge_v it_o or_o very_o inconsiderable_o in_o 24_o hour_n at_o last_o you_o may_v use_v water_n keep_v hot_a by_o a_o fire_n &c_n &c_n the_o better_a to_o extract_v the_o remain_v sal-volatile-oleosum_a evaporate_v all_o these_o last_o water_n in_o balneo_fw-la to_o the_o consistence_n of_o a_o extract_n this_o i_o call_v the_o solid_a panacea_fw-la of_o opium_n god_n and_o nature_n act_v by_o simple_a mean_n and_o nothing_o in_o imitation_n of_o they_o be_v more_o commendable_a in_o a_o medicament_n than_o simplicity_n therefore_o i_o shall_v add_v nothing_o to_o the_o panacea_n but_o whole_o
have_v spend_v month_n in_o prepare_v the_o sapo_n tartareus_fw-la to_o correct_v opium_n when_o they_o may_v with_o the_o hundred_o part_n of_o the_o trouble_v and_o forty_o part_n of_o the_o time_n whole_o have_v take_v away_o the_o pernicious_a part_n by_o aqueous_a menstruum_n which_o they_o only_o pretend_v to_o correct_v by_o the_o sapo_n tartareus_fw-la though_o i_o allow_v it_o for_o the_o reason_n aforesaid_a to_o be_v a_o good_a corrector_n yet_o can_v it_o equal_v the_o total_a separation_n of_o the_o pernicious_a part_n i_o be_o of_o opinion_n upon_o my_o best_a thought_n and_o some_o experience_n that_o intimate_o mix_v and_o subdue_a opium_n with_o good_a white_a soap_n may_v for_o the_o reason_n aforesaid_a prove_v a_o good_a and_o ready_a corrector_n or_o preventer_n of_o the_o adhesion_n of_o the_o resinous_a part_n of_o opium_n to_o the_o stomach_n much_o conduce_v to_o its_o dissolution_n or_o digestion_n therein_o and_o nimble_a slip_n out_o of_o it_o and_o thereby_o prevent_v all_o the_o ill_a effect_n of_o opium_n which_o it_o cause_v by_o the_o adhesion_n and_o indigestibleness_n of_o its_o rosin_n of_o the_o second_o sort_n of_o preparation_n of_o opium_n wherein_o its_o rosin_n remain_v whole_o unaltered_a in_o its_o nature_n yet_o become_v safe_a by_o divide_v it_o etc._n etc._n this_o be_v main_o if_o not_o altogether_o do_v by_o a_o fine_a and_o through_o division_n of_o the_o resinous_a part_n of_o opium_n and_o keep_v they_o afterward_o from_o a_o coalescence_n in_o and_o adhesion_n to_o the_o stomach_n by_o which_o mean_n they_o become_v digestible_a or_o at_o least_o passable_a without_o offence_n this_o may_v be_v do_v 1._o by_o torrefaction_n till_o the_o opium_n be_v very_o friable_a and_o then_o fine_o powder_a it_o and_o mix_v it_o with_o such_o thing_n as_o be_v of_o good_a consistence_n etc._n etc._n to_o keep_v the_o part_n of_o opium_n from_o a_o coalescence_n as_o in_o venice_n treacle_n mithridate_n diascordium_n the_o philonium_n etc._n etc._n this_o be_v the_o way_n and_o method_n that_o the_o ancient_n use_v which_o cause_v galen_n to_o say_v that_o opium_n alone_o that_o be_v undivided_a and_o unmixed_a with_o other_o thing_n to_o prevent_v its_o coalescence_n etc._n etc._n be_v dangerous_a but_o mix_v with_o other_o thing_n be_v salutiferous_a which_o they_o find_v by_o experience_n not_o know_v the_o cause_n but_o attribute_v the_o safety_n thereof_o to_o something_o among_o the_o many_o ingredient_n as_o a_o corrector_n of_o the_o opium_n hence_o it_o be_v that_o they_o put_v small_a quantity_n thereof_o into_o electuary_n make_v of_o many_o and_o much_o other_o thing_n that_o keep_v the_o particle_n asunder_o which_o they_o do_v so_o common_o that_o at_o last_o all_o electuary_n be_v call_v opiate_n thus_o we_o have_v those_o composition_n above_o name_v which_o be_v safe_o use_v for_o the_o reason_n aforesaid_a not_o that_o any_o thing_n therein_o correct_v i_o know_v not_o what_o poisonous_a or_o narcotick_a quality_n in_o opium_n but_o that_o the_o other_o ingredient_n divide_v its_o rosin_n and_o afterward_o keep_v its_o particle_n from_o coalescence_n and_o adhesion_n 2._o dissolution_n of_o opium_n in_o spirit_n of_o wine_n or_o such_o sulphureous_a spirit_n which_o fine_o divide_v the_o rosin_n and_o use_v the_o bare_a tincture_n before_o the_o resinous_a particle_n be_v again_o compact_v as_o in_o extract_n etc._n etc._n may_v be_v of_o use_n if_o due_o administer_v but_o here_o a_o caution_n be_v to_o be_v use_v that_o you_o take_v it_o not_o in_o or_o drink_v any_o aqueous_a or_o phlegmatic_a liquid_a with_o it_o or_o before_o or_o after_o it_o in_o two_o or_o three_o hour_n which_o if_o you_o do_v the_o resinous_a particle_n will_v be_v precipitate_v thereby_o and_o so_o stick_v to_o the_o bottom_n tom_fw-mi of_o the_o stomach_n cause_v thereby_o the_o usual_a ill_a effect_n of_o vomit_v anxiety_n etc._n etc._n therefore_o it_o shall_v be_v give_v only_o in_o a_o spirituous_a liquid_a note_v also_o that_o if_o you_o give_v a_o solution_n thereof_o in_o any_o lixivium_n you_o take_v care_v not_o to_o dilate_v it_o by_o any_o mean_n by_o aqueous_a liquid_n in_o two_o hour_n before_o or_o after_o you_o take_v it_o for_o then_o there_o be_v but_o little_a lixivial_a salt_n in_o proportion_n to_o the_o liquid_a the_o resinous_a part_n be_v let_v go_v and_o precipitate_v to_o the_o bottom_n of_o the_o stomach_n as_o in_o the_o case_n of_o the_o spirit_n of_o wine_n so_o dilate_v of_o which_o i_o have_v see_v a_o very_a convince_a instance_n for_o one_o that_o have_v a_o esteem_n of_o lixivial_o in_o this_o case_n not_o only_o according_a to_o helmont_n and_o the_o common_a cry_n to_o correct_v opium_n but_o also_o to_o extract_v its_o virtue_n the_o more_o effectual_o make_v a_o tincture_n of_o opium_n in_o water_n lixiviate_v with_o salt_n of_o wormwood_n whereof_o he_o take_v the_o quantity_n that_o he_o have_v see_v i_o give_v of_o my_o liquid_a panacea_fw-la in_o a_o coffee-dish_n full_a of_o water_n which_o precipitate_v the_o rosin_n in_o the_o stomach_n cause_v he_o to_o vomit_v in_o about_o a_o hour_n after_o and_o continue_v so_o to_o do_v for_o about_o 15_o hour_n by_o which_o you_o plain_o see_v that_o the_o great_a secret_a of_o lixivial_o to_o correct_v opium_n lie_v mere_o in_o its_o division_n of_o the_o rosin_n thereof_o as_o in_o the_o case_n of_o spirit_n of_o wine_n and_o powder_a it_o and_o afterward_o keep_v its_o particle_n asunder_o during_o its_o stay_n at_o stomach_n which_o the_o sapo_n tartareus_fw-la do_v and_o probable_o other_o soap_n may_v do_v very_o well_o for_o the_o several_a reason_n aforesaid_a 3._o dissolution_n of_o opium_n in_o the_o yolk_n of_o a_o rear_n new_o lay_v egg_n by_o pound_v the_o dose_n that_o you_o intend_v to_o take_v with_o a_o little_a quantity_n of_o the_o yolk_n till_o both_o be_v thorough_o mix_v and_o then_o take_v it_o in_o the_o remain_a part_n of_o the_o yolk_n by_o which_o mean_v you_o not_o only_o fine_o divide_v the_o resinous_a part_n of_o the_o opium_n while_o the_o yolk_n of_o the_o egg_n intimate_o mix_v with_o they_o as_o it_o do_v with_o other_o rosin_n and_o turpentine_n but_o send_v along_o with_o it_o into_o the_o stomach_n what_o be_v digestible_a in_o itself_o and_o more_o and_o more_o divide_v and_o separate_v the_o resinous_a part_n and_o high_o contribute_v to_o their_o final_a dissolution_n and_o digestion_n so_o that_o i_o doubt_v not_o but_z you_o will_v find_v this_o new_a ready_a and_o agreeable_a mean_n as_o good_a if_o not_o better_o all_o thing_n consider_v than_o the_o former_a and_o even_o equal_a to_o the_o sapo_n tartareus_fw-la by_o what_o be_v say_v though_o short_a you_o may_v because_o it_o be_v the_o clear_a truth_n of_o thing_n judge_v of_o the_o goodness_n of_o all_o preparation_n of_o opium_n and_o 1._o that_o resinous_a thing_n shall_v not_o be_v add_v to_o opium_n because_o such_o like_o its_o own_o rosin_n render_v it_o more_o indigestible_a and_o apt_a to_o stick_v at_o stomach_n hence_o it_o be_v that_o the_o styrax_fw-mi pill_n have_v resinous_a thing_n in_o it_o and_o crude_a opium_n do_v so_o often_o cause_v dismal_a effect_n though_o forsooth_o much_o esteem_v for_o the_o lung_n cough_n defluxion_n etc._n etc._n for_o have_v such_o balsamic_a resinous_a thing_n as_o styrax_n and_o olibanum_n in_o it_o whereas_o the_o benefit_n be_v from_o the_o opium_n have_v dr._n bates_n know_v the_o cause_n of_o the_o mischief_n of_o opium_n he_o will_v never_o have_v put_v benjamin_n in_o his_o pacifick_n pill_n 2._o that_o all_o preparation_n make_v of_o extract_n in_o spirit_n of_o wine_n be_v to_o be_v reject_v such_o extract_v be_v much_o worse_a than_o crude_a opium_n and_o experimental_o find_v to_o be_v so_o therefore_o our_o common_a london_n laudanum_n be_v make_v of_o opium_n prepare_v in_o spirit_n of_o wine_n be_v no_o commendable_a preparation_n though_o so_o much_o use_v and_o cry_v up_o which_o also_o experience_n prove_v in_o that_o it_o sometime_o cause_v the_o ill_a effect_n of_o opium_n when_o give_v alone_o in_o a_o good_a do_v you_o will_v find_v more_o of_o these_o matter_n when_o you_o come_v to_o chap._n 29._o which_o consist_v of_o general_a rule_n and_o caution_n concern_v the_o use_n of_o opium_n therefore_o though_o i_o may_v add_v some_o useful_a observation_n i_o put_v a_o end_n to_o this_o matter_n at_o present_a for_o that_o reason_n and_o because_o what_o be_v to_o be_v true_o do_v in_o the_o preparation_n of_o opium_n be_v very_o evident_a from_o what_o be_v say_v since_o the_o cause_n of_o the_o ill_a effect_n of_o opium_n be_v now_o certain_o know_v to_o be_v its_o rosin_n to_o the_o separation_n or_o due_a alteration_n of_o which_o so_o as_o to_o cause_v it_o to_o pass_v the_o stomach_n without_o adhesion_n or_o offence_n by_o
its_o stay_n or_o indigestibleness_n all_o regard_n must_v be_v have_v in_o the_o preparation_n thereof_o as_o be_v in_o the_o follow_a preparation_n which_o be_v therefore_o safe_a chap._n xxvii_o show_v the_o best_a preparation_n of_o opium_n where_o to_o find_v they_o and_o what_o be_v their_o respective_a dose_n etc._n etc._n you_o may_v infer_v out_o of_o the_o premise_n which_o be_v the_o best_a preparation_n of_o opium_n viz._n 1._o such_o as_o have_v the_o resinous_a part_n of_o opium_n separate_v from_o they_o as_o 1._o the_o liquid_a panacea_fw-la of_o opium_n describe_v in_o c._n 25._o of_o this_o book_n 2._o the_o solid_a panacea_fw-la of_o opium_n describe_v in_o c._n 25._o of_o this_o book_n 3._o diacodium_fw-la or_o sir_n e_o mecon_fw-mi in_o the_o london_n dispensatory_a 4._o laudanum_n liquidum_fw-la cydoniatum_n in_o experience_a mr._n wilson_n chemistry_n and_o in_o curious_a mr._n staphurst_n officina_fw-la chymica_fw-la londinensis_fw-la note_v that_o there_o be_v several_a needless_a proceed_n in_o this_o preparation_n as_o that_o of_o put_v yeast_n to_o it_o etc._n etc._n let_v your_o aim_n in_o make_v it_o be_v to_o separate_v the_o resinous_a part_n therefore_o instead_o of_o two_o expression_n direct_v use_v only_o a_o careful_a decantation_n because_o the_o rosin_n may_v pass_v by_o express_v it_o 5._o wedelius_n laudanum_n which_o be_v his_o opilogia_n l._n 1._o sect._n 2._o cap._n 2._o p._n 65._o note_v that_o the_o spumou_n part_v on_o the_o surface_n be_v to_o be_v take_v off_o and_o the_o clear_a tincture_n to_o be_v decant_v from_o the_o faeces_fw-la and_o afterward_o evaporate_v in_o balneo_fw-la to_o the_o consistence_n of_o a_o extract_n 6._o le_fw-fr mort's_n extract_n out_o of_o rain-water_n which_o you_o have_v in_o the_o most_o learned_a dr._n love_n collectanea_fw-la chymica_fw-la p._n 304._o ii_o such_o preparation_n wherein_o the_o resinous_a part_n of_o opium_n be_v alter_v and_o as_o it_o be_v soapify_v by_o lixivial_a salt_n or_o soaps_o viz._n 1._o dr._n starkey_n or_o matthews_n piâ—l_o which_o you_o have_v in_o mr._n wilson_n chemistry_n p._n 271_o 272._o in_o ingenious_a mr._n shipton_n pharmacopâ—ia_n bateana_n among_o the_o pill_n and_o in_o mr._n staphurst_n officina_fw-la chymica_fw-la londinensis_fw-la among_o the_o laudanum_n p_o 51._o note_v that_o the_o main_a thing_n to_o be_v regard_v in_o 〈◊〉_d make_v up_o of_o this_o pill_n be_v 1._o to_o spare_v no_o labour_n in_o pound_v subdue_a and_o intimate_o mix_v the_o sapo_n tartareus_fw-la and_o the_o opium_n 2._o that_o the_o sapo_n shall_v be_v twice_o as_o much_o as_o the_o opium_n that_o it_o may_v the_o better_o subdue_v the_o resinous_a part_n of_o the_o opium_n note_v that_o as_o to_o the_o other_o thing_n contain_v in_o the_o â—aid_a pill_n they_o may_v or_o other_o thing_n be_v add_v or_o omit_v according_a to_o the_o intention_n of_o the_o physician_n only_o this_o i_o say_v that_o it_o be_v very_o convenient_a other_o thing_n shall_v be_v add_v to_o the_o sapo_n and_o opium_n the_o better_a to_o separate_v and_o disgregate_v the_o part_n of_o the_o opium_n as_o have_v be_v intimate_v note_v that_o if_o the_o mass_n be_v too_o dry_a you_o may_v as_o mr._n wilson_n direct_v use_v some_o of_o the_o oil_n that_o separate_v from_o the_o soap_n or_o rectify_v oil_n of_o turpentine_n q._n s._n to_o moisten_v it_o 2._o dr._n bates_n pacific_a pill_n which_o you_o have_v among_o the_o pill_n in_o mr._n shipton_n pharmacopâ—ia_n bateana_n note_v that_o the_o same_o thing_n be_v to_o be_v observe_v as_o to_o this_o and_o starkey_n pill_n in_o all_o particular_n note_v that_o the_o benjamin_n shall_v be_v omit_v as_o be_v resinous_a iii_o such_o preparation_n of_o opium_n wherein_o its_o resinous_a part_n remain_v unaltered_a in_o themselves_o yet_o so_o divide_v separate_a etc._n etc._n as_o to_o be_v render_v innocent_a such_o be_v all_o which_o you_o have_v in_o the_o london_n dispensatory_a 1._o venice_n treacle_n 2._o philoneum_fw-la persicum_fw-la 3._o philoneum_fw-la romanum_fw-la 4._o diascordiuâ—_n 5._o mithridate_n note_v that_o in_o all_o these_o preparation_n the_o opium_n shall_v be_v careful_o mix_v with_o the_o other_o ingredient_n and_o to_o that_o end_n either_o torrify_v and_o fine_o powder_v or_o dissolve_v in_o water_n which_o divide_v all_o its_o part_n and_o then_o thorough_o mix_v with_o the_o other_o ingredient_n while_o it_o be_v off_o or_o after_o it_o be_v reduce_v by_o evaporation_n to_o the_o consistence_n of_o a_o syrup_n or_o somewhat_o thin_a 6._o sydenbam_n laudanum_n which_o you_o will_v find_v in_o mr._n wilson_n chemistry_n note_v that_o the_o main_a care_n in_o this_o preparation_n be_v to_o let_v the_o liquor_n have_v a_o sufficient_a time_n to_o clear_v from_o the_o fâ—ces_n and_o to_o separate_v from_o it_o that_o you_o may_v by_o that_o mean_n have_v less_o of_o the_o rosin_n note_v that_o this_o be_v best_a give_v in_o a_o spirituous_a liquid_a lest_o its_o rosin_n though_o it_o can_v have_v much_o in_o it_o if_o well_o decant_v be_v precipitate_v at_o stomach_n note_v that_o the_o henbane-seed_n in_o the_o philonium_n shall_v be_v leave_v out_o 1._o because_o it_o make_v the_o do_v more_o uncertain_a 2._o because_o it_o be_v not_o to_o be_v esteem_v so_o much_o as_o opium_n at_o least_o you_o multiply_v thing_n without_o necessity_n in_o put_v it_o in_o note_v that_o pil._n e_fw-la cynoglosso_fw-la as_o be_v say_v in_o the_o last_o chapter_n of_o pil._n e_o styrace_n be_v a_o very_a ill_a composition_n both_o upon_o the_o account_n of_o the_o resinous_a thing_n that_o it_o contain_v as_o also_o the_o resinous_a preparation_n of_o opium_n that_o it_o be_v make_v of_o and_o therefore_o do_v as_o that_o e_z styrace_n often_o cause_v grievous_a effect_n nor_o do_v i_o think_v the_o london_n laudanum_n who_o name_n do_v probable_o recommend_v it_o more_o than_o any_o thing_n else_o worthy_a a_o place_n among_o the_o best_a and_o safe_a preparation_n because_o the_o opium_n be_v render_v worse_o or_o more_o resinous_a than_o the_o crude_a by_o be_v extract_v out_o of_o spirit_n of_o wine_n and_o because_o it_o have_v too_o few_o other_o ingredient_n to_o divide_v segregate_v and_o keep_v its_o resinous_a part_n from_o coalescence_n so_o that_o it_o may_v and_o sometime_o do_v cause_n ill_a symptom_n so_o philonium_fw-la magistrale_fw-la be_v to_o be_v reject_v for_o the_o like_a reason_n beside_o that_o it_o be_v otherwise_o a_o foolish_a preparation_n because_o opium_n benjamin_n myrrh_n and_o mummy_n be_v order_v to_o be_v make_v a_o opiate_n or_o electuary_n with_o spirit_n of_o wine_n which_o be_v ridiculous_a so_o troch_v the_o carabe_n and_o de_fw-fr terra_fw-la lemnia_n be_v not_o without_o their_o fault_n because_o one_o have_v frankincense_n and_o the_o other_o olibanum_fw-la in_o it_o which_o be_v resinous_a though_o but_o in_o a_o small_a quantity_n seif_n de_fw-mi thure_z have_v a_o great_a quantity_n of_o the_o frankincense_n be_v not_o commendable_a since_o the_o opium_n be_v also_o crude_a now_o have_v show_v you_o which_o be_v the_o best_a and_o worst_a preparation_n and_o why_o it_o remain_v that_o i_o show_v you_o the_o just_a dose_n of_o the_o best_a and_o soft_a who_o number_n be_v very_o sufficient_a to_o answer_v all_o intent_n without_o meddle_v with_o such_o as_o may_v not_o be_v so_o saâ—e_v or_o neat_a a_o explanation_n of_o the_o table_n of_o dose_n i_o have_v once_o add_v a_o explicatory_a table_n of_o the_o mark_v i_o use_v but_o afterward_o consider_v that_o all_o physician_n and_o good_a practitioner_n in_o physic_n do_v know_v they_o and_o that_o it_o be_v not_o fit_a to_o intrust_v other_o therewith_o therefore_o i_o shall_v only_o add_v something_o for_o the_o better_a and_o ready_a use_n of_o the_o premise_a table_n of_o dose_n 1._o note_v that_o the_o sort_n of_o person_n that_o you_o have_v to_o deal_v with_o be_v place_v in_o the_o uppermost_a space_n of_o the_o say_a table_n and_o the_o dose_n fit_a for_o such_o and_o such_o person_n put_v direct_o under_o they_o in_o the_o same_o column_n 2._o note_v that_o there_o be_v three_o sort_n of_o dose_n of_o every_o particular_a preparation_n that_o be_v the_o least_o middle_a and_o high_a do_v under_o every_o sort_n of_o man_n or_o woman_n which_o be_v also_o of_o three_o sort_n the_o strong_a middling_a and_o weak_a as_o you_o see_v in_o the_o upper_a space_n 3._o note_v therefore_o that_o when_o yond_o be_v about_o to_o give_v a_o opiate_n to_o any_o man_n or_o woman_n that_o you_o first_o look_n in_o that_o upper_a space_n for_o the_o sort_n of_o person_n you_o be_v to_o give_v it_o to_o as_o weak_a strong_a or_o middling_a man_n or_o woman_n then_o carry_v your_o eye_n down_o in_o that_o column_n till_o you_o come_v over_o against_o the_o preparation_n that_o you_o intend_v to_o give_v and_o there_o you_o will_v find_v in_o
the_o say_a column_n three_o sort_n of_o dose_n the_o low_a on_o the_o left_a hand_n the_o high_a on_o the_o right_a hand_n and_o the_o moderate_a do_v between_o they_o as_o suppose_v you_o be_v about_o to_o give_v a_o middle_n do_v of_o the_o liquid_a panacea_fw-la to_o a_o strong_a man_n see_v for_o strong_a man_n in_o the_o upper_a space_n and_o for_o liquid_a panacea_fw-la in_o the_o first_o column_n on_o the_o left_a hand_n under_o the_o word_n opiate_n and_o where_o the_o column_n that_o belong_v to_o strong_a man_n and_o the_o space_n that_o belong_v to_o liquid_a panacea_fw-la do_v meet_v there_o you_o will_v find_v qt_n 20_o 30_o 40_o for_o the_o least_o middle_a and_o high_a do_v give_v which_o you_o think_v fit_a according_a to_o your_o intention_n so_o if_o you_o be_v about_o to_o give_v the_o high_a do_v of_o the_o solid_a panacea_fw-la to_o a_o strong_a woman_n you_o will_v find_v under_o the_o word_n strong_a woman_n over_o against_o solid_a panacea_fw-la gr_fw-la i_o gr_n i¼_n gr_n i_o ss_z which_o show_v you_o that_o gr_n i_o ss_z be_v the_o high_a do_v for_o a_o strong_a woman_n and_o so_o of_o all_o the_o rest_n 4._o note_v that_o i_o have_v be_v so_o cautious_a in_o dose_v all_o the_o opiate_n that_o you_o may_v very_o safe_o give_v the_o high_a dose_n to_o all_o but_o very_o weak_a person_n to_o who_o it_o be_v hardly_o fit_a to_o give_v any_o thing_n by_o reason_n of_o extreme_a weakness_n 5._o note_v that_o if_o you_o give_v any_o to_o young_a person_n under_o the_o age_n of_o 20._o you_o shall_v proportion_v the_o dose_n not_o so_o much_o as_o idle_a custom_n direct_v according_a to_o their_o year_n as_o bulk_n and_o strength_n for_o instance_n allow_v strong_a man_n to_o be_v 200_o pound_n weight_n you_o must_v give_v a_o strong_a youth_n of_o 100_o pound_v weight_n half_o the_o do_v of_o the_o strong_a man_n and_o so_o of_o all_o other_o only_o allow_v somewhat_o less_o the_o young_a they_o be_v because_o of_o the_o softness_n fineness_n or_o laxity_n of_o their_o texture_n especial_o if_o they_o be_v very_o young_a to_o who_o opiate_n must_v be_v cautious_o give_v or_o only_o diacodium_fw-la which_o be_v best_a in_o that_o case_n and_o that_o in_o a_o small_a proportion_n also_o for_o young_a child_n can_v bear_v opiate_n as_o well_o as_o grow_v person_n no_o not_o in_o proportion_n to_o their_o bulk_n or_o weight_n place_v this_o between_o p._n 294_o and_o p._n 295._o a_o table_n of_o the_o dose_n of_o the_o best_a and_o safe_a opiate_n opiate_n do_v do_v do_v do_v liquid_a to_o strong_a man_n to_o middling_a man_n &_o strong_a woman_n to_o weak_a man_n &_o middling_a woman_n to_o weak_a woman_n the_o liquid_a panacea_fw-la gt_fw-mi 20_o 30_o 40_o 16_o 23_o 30_o 12_o 18_o 24_o 10_o 15_o 20_o laudanum_n liquidum_fw-la cydoniatum_n gt_fw-fr 20_o 30_o 40_o 16_o 23_o 30_o 12_o 18_o 24_o 10_o 15_o 20_o sydenham_n laudanum_n gt_v 20_o 30_o 40_o 16_o 23_o 30_o 12_o 18_o 24_o 10_o 15_o 20_o diacodium_fw-la or_o syr._n e_fw-it mecon_fw-mi ☞_o i_o Ê’x_o ☞_o ss_z ☞_o ss_z Ê’vi_fw-la ☞_o i_o ☞_o ss_z Ê’v_o Ê’vi_fw-la Ê’iii_fw-la ☞_o ss_z Ê’v_v solid_n  _fw-fr  _fw-fr  _fw-fr  _fw-fr the_o solid_a panacea_fw-la gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ay_o i¼_n gr_n ss_z ¾_n i_o wedelius_n laudanum_n gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ay_o i¼_n gr_n ss_z ¾_n i_z le_fw-fr mort_n extract_n gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ay_o i¼_n gr_n ss_z ¾_n i_o dr._n bate_n pacific_a pill_n gr_n two_o iiss_n three_o gr_n i_o iss_v two_o gr_n i_o i¼_n iss_v gr_n ss_z ¾_n ay_o starkey_n or_o matthew_n pill_n gr_n vi_fw-la ix_o twelve_o gr_n v_o seven_o ix_o gr_n four_o vi_fw-la viij_o gr_n three_o four_o v_a philonium_fw-la romanum_fw-la Ê’ss_n ℈_o two_o Ê’i_fw-la ℈_o i_o Ê’ss_n ℈_o two_o gr_n xviii-xxiv_a Ê’ss_v gr_n xuj_o xx_o xxiv_o philonium_fw-la persicum_fw-la Ê’ss_n ℈_o two_o Ê’i_fw-la ℈_o i_o Ê’ss_o ℈_o two_o gr_n xviii-xxiv_a Ê’ss_v gr_n xuj_o xx_o xxiv_o venice_n treacle_n Ê’i_fw-it Ê’ii_fw-la Ê’iii_fw-la Ê’i_fw-la Ê’iss_v Ê’ii_fw-la ℈_o two_o Ê’i_fw-la ℈_o iiii_o Ê’ss_n ℈_o two_o Ê’i_fw-la mithridate_n ☞_o ss_z Ê’vi_fw-la ☞_o i_o Ê’iii_fw-la Ê’v_o Ê’vii_fw-la Ê’ii_fw-la ☞_o ss_z Ê’vi_fw-la Ê’ii_fw-la Ê’iii_fw-la ☞_o ss_z diascordium_fw-la ☞_o ss_z Ê’vi_fw-la ☞_o i_o Ê’iii_fw-la Ê’v_o Ê’vii_fw-la Ê’ii_fw-la ☞_o ss_z Ê’vi_fw-la Ê’ii_fw-la Ê’ii_fw-la ☞_o ss_z the_o dose_n of_o london_n laudanum_n which_o i_o mention_v rather_o for_o its_o general_a use_n than_o laudableness_n may_v be_v the_o same_o with_o that_o of_o the_o pacifick_n pill_n a_o table_n of_o mark_n very_o necessary_a for_o the_o better_a understanding_n of_o the_o table_n of_o dose_n gt_fw-fr signify_v a_o drop_n 〈◊〉_d signify_v a_o grain_n 〈◊〉_d signify_v a_o scruple_n which_o be_v 20_o grainâ—_n 〈◊〉_d or_o ☜_o signify_v a_o dram_n which_o be_v 3_o scruple_n 〈◊〉_d signify_v a_o ounce_n which_o be_v 8_o dramâ—_n or_o drachm_n â—_o â—_o signifieâ—_n a_o quarter_n of_o any_o to_n â—_o â—_o â—_o â—_o ss_z or_o ss_z signifieâ—_n half_a of_o any_o to_n â—_o â—_o signifieâ—_n 3_o quarter_n of_o any_o to_a chap._n xxviii_o the_o cure_n of_o the_o ill_a effect_n of_o opium_n have_v show_v how_o to_o prepare_v opium_n so_o as_o to_o render_v it_o safe_a and_o innocent_a in_o a_o moderate_a do_v and_o how_o much_o that_o moderate_a do_v be_v one_o may_v be_v apt_a to_o think_v that_o this_o chapter_n be_v needless_a but_o when_o you_o consider_v how_o many_o there_o be_v that_o may_v be_v negligent_a wilful_a want_v time_n skill_n etc._n etc._n to_o prepare_v it_o or_o take_v too_o much_o or_o too_o long_o of_o it_o and_o that_o the_o physician_n must_v be_v able_a to_o answer_n and_o remedy_n all_o ill_a accident_n that_o may_v happen_v you_o will_v find_v it_o very_o requisite_a that_o i_o shall_v show_v how_o to_o cure_v the_o ill_a effect_n of_o opium_n which_o proceed_v either_o 1._o from_o its_o rosin_n at_o stomach_n or_o 2._o from_o too_o much_o relaxation_n by_o a_o excessive_a do_v or_o 3._o from_o a_o long_a and_o lavish_a use_n of_o it_o or_o 4._o from_o a_o sudden_a leave_v it_o off_o after_o a_o long_a and_o lavish_a use_v thereof_o i._o to_o cure_v the_o ill_a effect_n of_o the_o rosin_n at_o stomach_n you_o be_v first_o to_o know_v whether_o that_o be_v the_o cause_n which_o you_o may_v learn_v 1._o by_o consider_v whether_o crude_a opium_n or_o some_o resinous_a preparation_n thereof_o be_v take_v especial_o by_o itself_o in_o the_o form_n of_o a_o pill_n or_o pill_n as_o a_o extract_v thereof_o out_o of_o spirit_n of_o wine_n or_o pilâ—e_a styrace_n or_o london_n laudanum_n or_o the_o like_a not_o due_o prepare_v as_o have_v be_v direct_v 2._o by_o the_o symptom_n which_o be_v these_o viz._n a_o nausea_n puke_v vomit_v hiccough_n convulsion_n distress_n and_o anxiety_n about_o the_o stomach_n particular_o the_o part_n call_v the_o pit_n of_o the_o stomach_n swimmings_n in_o the_o head_n vertigo_n palpitation_n and_o tremble_n of_o the_o heart_n agitation_n uneasiness_n a_o turbulent_a pulse_n and_o after_o a_o struggle_v of_o nature_n under_o those_o symptom_n faint_n leipothymy_n syncopes_fw-la etc._n etc._n which_o last_o you_o must_v not_o take_v for_o certain_a sign_n and_o symptom_n unless_o the_o former_a have_v precede_v they_o because_o it_o be_v not_o impossible_a but_o they_o may_v happen_v from_o the_o quantity_n of_o the_o opium_n condition_n or_o constitution_n of_o the_o person_n etc._n etc._n but_o this_o when_o all_o thing_n be_v compare_v together_o will_v be_v easy_o judge_v of_o especial_o if_o you_o observe_v 1._o whether_o those_o faint_n or_o leipothymy_n be_v not_o more_o like_o the_o failure_n and_o stupor_n of_o drunkard_n than_o bare_a faint_n if_o they_o be_v of_o the_o first_o sort_n then_o do_v they_o proceed_v from_o a_o over_o relaxation_n occasion_v by_o the_o opium_n and_o not_o from_o its_o rosin_n the_o cure_n of_o which_o belong_v to_o the_o second_o particular_a 2._o whether_o they_o be_v more_o attend_v with_o the_o sign_n of_o relaxation_n as_o deadness_n of_o the_o eye_n falter_v of_o the_o tongue_n darkness_n before_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la efflorescence_n of_o the_o skin_n laxity_n of_o the_o limb_n want_v of_o feel_v stupidity_n sleepiness_n failure_n of_o the_o sense_n or_o of_o make_v water_n loss_n of_o memory_n or_o understanding_n a_o dry_a mouth_n a_o slow_a and_o wide_a pulse_n and_o other_o thing_n much_o like_o the_o state_n of_o a_o deadish_a drunkenness_n for_o then_o those_o failure_n be_v the_o effect_n of_o relaxation_n by_o the_o pleasant_a sensation_n that_o the_o opium_n cause_n but_o after_o all_o it_o be_v the_o sort_n of_o opium_n that_o be_v take_v and_o
part_n themselves_o do_v also_o due_o contract_n which_o opium_n hinder_v 6._o you_o have_v much_o the_o same_o reason_n not_o to_o give_v they_o soon_o after_o other_o large_a evacuation_n where_o a_o due_a contraction_n of_o the_o part_n be_v requisite_a as_o after_o tapping_n or_o paracentesis_n in_o dropsy_n childbirth_n etc._n etc._n 7._o opiate_n be_v best_a give_v in_o the_o morning_n to_o cause_n euphory_n or_o brisk_a effect_n because_o the_o refreshment_n gain_v by_o the_o night_n sleep_n do_v not_o only_o concur_v towards_o euphory_n and_o briskness_n but_o also_o much_o oppose_v sleepiness_n and_o drowsiness_n which_o be_v not_o consistent_a with_o brisk_a effect_n vi_o as_o to_o person_n 1._o it_o be_v not_o convenient_a to_o give_v opiate_n to_o person_n very_o young_a or_o very_a old_a 2._o they_o agree_v better_o with_o man_n than_o woman_n or_o child_n with_o man_n of_o a_o robu_v and_o hard_a rather_o than_o of_o a_o weak_a fine_a tender_a and_o soft_a texture_n with_o such_o as_o have_v a_o strong_a digestion_n than_o a_o weak_a and_o in_o general_a with_o the_o strong_a rather_o than_o the_o weak_a therefore_o 3._o never_o give_v they_o to_o person_n that_o be_v very_o weak_a especial_o if_o they_o take_v or_o digest_v no_o sustenance_n or_o extreme_o little_a for_o reason_n already_o give_v nor_o to_o such_o as_o be_v near_o their_o end_n or_o almost_o expire_a ☞_o except_o it_o be_v for_o want_v of_o opium_n or_o by_o extremity_n of_o contraction_n by_o terror_n pain_n cold_a convulsion_n etc._n etc._n for_o than_o it_o will_v do_v wonder_n in_o preserve_a people_n that_o be_v otherwise_o past_a all_o hope_n by_o relax_v take_v away_o pain_n contraction_n etc._n etc._n 4._o it_o be_v not_o so_o agreeable_a to_o the_o very_a fat_a or_o moist_a because_o they_o may_v be_v over-relaxed_n nor_o to_o the_o very_a lean_a and_o dry_a etc._n etc._n especial_o to_o cause_n sleep_n because_o it_o be_v apt_a to_o irritate_fw-la and_o actuate_v their_o spirit_n too_o much_o by_o which_o mean_v sleep_n be_v much_o hinder_v vii_o as_o to_o malady_n and_o disease_n etc._n etc._n i._o opiate_n be_v not_o convenient_a in_o relaxation_n as_o such_o as_o general_a palsy_n hemiphlegia_n palsy_n of_o the_o eye_n deadness_n of_o they_o dilatation_n of_o the_o pupil_n relaxation_n of_o the_o tympan_n of_o the_o ear_n of_o one_o side_n of_o the_o face_n which_o make_v the_o other_o side_n contract_n and_o and_o so_o draw_v the_o face_n awry_o for_o it_o be_v not_o a_o spasm_n or_o convulsion_n as_o man_n imagine_v of_o the_o contract_a side_n but_o a_o resolution_n of_o the_o other_o which_o permit_v the_o antagonist_n muscle_n of_o that_o side_n to_o contract_n without_o opposition_n and_o draw_v the_o face_n towards_o the_o strong_a or_o sound_a side_n relaxation_n of_o the_o uuula_fw-la or_o the_o annex_v value_n which_o last_o be_v know_v by_o snuffle_v without_o any_o other_o evident_a cause_n or_o by_o observe_v that_o it_o do_v not_o shut_v in_o sound_a u_o in_o but_o cut_z etc._n etc._n by_o itself_o relaxation_n of_o the_o larynx_n and_o windpipe_n which_o be_v know_v by_o a_o hoarse_a kind_n of_o whisper_n without_o a_o cold_a or_o any_o evident_a cause_n of_o the_o pharynx_n or_o gullet_n which_o be_v know_v by_o a_o depravation_n of_o swallow_v without_o pain_n or_o tumour_n or_o any_o evident_a cause_n a_o paralytical_a asthma_n or_o difficulty_n of_o breathe_v wherein_o man_n heave_v the_o shoulder_n without_o any_o apparent_a cause_n relaxation_n of_o the_o stomach_n as_o when_o meat_n stay_v too_o long_o at_o stomach_n etc._n etc._n a._n palsy_n of_o the_o intestine_n or_o gut_n as_o when_o one_o be_v bind_v and_o can_v refer_v it_o to_o any_o other_o cause_n of_o the_o bladder_n when_o one_o can_v make_v water_n without_o any_o other_o cause_n to_o refer_v it_o to_o relaxation_n of_o the_o sphincter_n of_o the_o bladder_n and_o anâ—_n that_o be_v when_o urine_n or_o ordure_n fall_v from_o one_o involuntary_o nor_o be_v they_o convenient_a in_o bath_n unless_o great_a relaxation_n as_o for_o passage_n of_o the_o stone_n etc._n etc._n be_v intend_v nor_o in_o rupture_n as_o bronchocele_v of_o the_o windpipe_n exomphalos_n of_o the_o navel_n bubonocele_n of_o the_o groin_n or_o the_o fall_n of_o humour_n gut_n fat_a etc._n etc._n into_o the_o scrotum_fw-la or_o of_o the_o fundament_n womb_n or_o the_o vagina_n etc._n etc._n except_o it_o be_v to_o reduce_v they_o nor_o in_o lunation_n sprain_n laxity_n and_o weakness_n of_o joint_n limb_n back_o etc._n etc._n extension_n of_o nerve_n tendon_n ligament_n etc._n etc._n nor_o where_o relaxation_n do_v or_o may_v improve_v the_o distemper_n or_o do_v harm_n as_o in_o apoplectical_a and_o soporose_a case_n as_o coma_n caros_n lethargy_n etc._n etc._n weakness_n of_o memory_n stupidity_n morosiâ—_n nightmare_n drunkenness_n etc._n etc._n syncopes_fw-la and_o faint_n from_o relaxation_n as_o the_o original_a cause_n as_o from_o excess_n of_o joy_n pleasure_n large_a evacuation_n when_o the_o part_n can_v well_o and_o due_o contract_v upon_o what_o remain_v as_o after_o childbirth_n profuse_a hemorrhage_n tapping_n or_o paracentesis_n or_o any_o large_a evacuation_n of_o humour_n in_o dropsy_n of_o the_o belly_n breast_n or_o head_n nor_o as_o have_v be_v hint_v in_o dropsy_n though_o without_o any_o such_o evacuation_n unless_o it_o be_v upon_o some_o special_a consideration_n of_o the_o learned_a nor_o in_o tremble_n or_o shake_v of_o the_o head_n or_o hand_n etc._n etc._n from_o weakness_n as_o in_o old_a age_n nor_o in_o flux_n from_o relaxation_n as_o too_o much_o sweat_n gonorrhaea_n simplex_n diabetes_n nocturnal_a pollution_n chylous_a flux_n lientery_n involuntary_a flux_n of_o urine_n or_o ordure_n and_o some_o sort_n of_o immoderate_a flux_n of_o the_o menses_fw-la or_o lochia_n which_o owe_v their_o cause_n to_o relaxation_n or_o aptitude_n to_o abortion_n from_o that_o cause_n and_o indeed_o general_o in_o woman_n with_o child_n lest_o it_o shall_v cause_v abortion_n by_o relax_v the_o neck_n of_o the_o womb._n or_o where_o contraction_n be_v beneficial_a as_o to_o empty_v a_o foul_a or_o replete_a stomach_n choler_n etc._n etc._n by_o vomit_v or_o stool_n or_o a_o ill_a humour_n any_o way_n therefore_o ii_o opiate_n be_v not_o convenient_a when_o grievous_a sensation_n be_v useful_a as_o to_o excite_v expectoration_n when_o matter_n threaten_v suffocation_n in_o vomicas_fw-la pleurisy_n peripneumonias_n consumption_n spit_v of_o blood_n etc._n etc._n when_o hunger_n call_v for_o food_n and_o restaurative_n that_o of_o stuff_v at_o stomach_n excite_v vomit_v that_o of_o urine_n solicit_v we_o to_o a_o due_a excretion_n thereof_o that_o of_o ill_a matter_n at_o gut_n cause_v a_o evacuation_n thereof_o so_o that_o when_o a_o crisis_n be_v to_o be_v by_o the_o help_n of_o grievous_a sensation_n or_o irritation_n opiate_n be_v not_o convenient_a for_o it_o take_v off_o the_o sense_n of_o irritation_n but_o when_o a_o crisis_n be_v to_o be_v by_o relaxation_n as_o by_o open_v the_o pore_n to_o cause_n sweat_n perspiration_n etc._n etc._n then_o be_v it_o of_o excellent_a use_n so_o that_o great_a question_n that_o have_v very_o much_o puzzle_v the_o learned_a whether_o opium_n be_v convenient_a before_o a_o crisis_n &_o c_o be_v plain_o and_o mechanical_o answer_v iii_o opiate_n be_v not_o convenient_a where_o titillation_n by_o the_o acrimony_n of_o volatile_a salt_n be_v the_o cause_n of_o the_o disease_n as_o in_o troublesome_a erection_n priapism_n nocturnal_a pollution_n venereal_a fury_n too_o much_o salacity_n and_o titillation_n itch_n of_o the_o uterus_fw-la scrotum_fw-la penis_n skin_n in_o general_n etc._n etc._n iv_o i_o scarce_o need_v tell_v any_o that_o opiate_n be_v inconvenient_a when_o the_o meconium_n of_o child_n shall_v be_v evacuate_v or_o when_o one_o be_v bind_v in_o body_n or_o apt_a to_o be_v so_o but_o there_o may_v be_v a_o time_n when_o the_o learned_a physician_n may_v think_v fit_a to_o give_v they_o even_o to_o the_o costive_a in_o urgent_a case_n for_o he_o can_v order_v somewhat_o along_o with_o they_o or_o soon_o after_o to_o open_v the_o body_n who_o may_v also_o see_v cause_n sometime_o to_o vary_v from_o these_o general_a rule_n when_o necessity_n and_o good_a reason_n direct_v he_o so_o to_o do_v though_o they_o be_v nevertheless_o general_a in_o their_o nature_n and_o not_o to_o be_v transgress_v without_o special_a cause_n and_o mature_a deliberation_n v._o opiate_n be_v not_o so_o convenient_a where_o there_o be_v much_o slimy_a moist_a and_o phlegmatic_a humour_n by_o reason_n that_o the_o part_n be_v subject_a in_o such_o case_n to_o be_v too_o much_o relax_v i_o have_v be_v the_o full_a especial_o upon_o the_o head_n of_o disease_n that_o i_o may_v hereafter_o have_v nothing_o to_o do_v but_o to_o show_v the_o beneficial_a use_n of_o opiate_n due_o prepare_v more_o particular_o of_o the_o panacea_n
of_o opium_n of_o which_o i_o be_o go_v to_o speak_v chap._n xxx_o the_o method_n contrive_v to_o show_v the_o use_n of_o well-prepared_n opiate_n more_o especial_o the_o panacea_fw-la of_o opium_n have_v show_v the_o nature_n and_o principle_n of_o opium_n which_o produce_v the_o good_a which_o the_o bad_a effect_n how_o and_o why_o they_o do_v so_o how_o to_o separate_v subdue_v and_o correct_v the_o bad_a principle_n the_o due_a dose_n of_o good_a preparation_n how_o to_o cure_v all_o the_o ill_a effect_n of_o opium_n and_o general_a rule_n and_o caution_n concern_v it_o and_o in_o what_o case_n it_o may_v not_o be_v convenient_a i_o have_v now_o nothing_o to_o do_v but_o to_o shâ—w_v the_o beneficial_a use_n of_o the_o panacea_fw-la or_o well_o prepare_v opiate_n to_o make_v it_o more_o agreeable_a to_o rational_a mind_n and_o fix_v its_o uses_n better_a in_o memory_n i_o will_v so_o proceed_v by_o its_o effect_n that_o the_o very_a title_n of_o every_o chapter_n may_v imply_v the_o reason_n of_o its_o use_n which_o be_v either_o internal_a or_o external_a and_o both_o of_o they_o either_o i._o as_o it_o be_v a_o pleaser_n of_o sensation_n or_o a_o opiate_n special_o so_o call_v by_o which_o mean_v it_o produce_v all_o the_o good_a effect_n that_o be_v notorious_o observe_v which_o be_v mention_v in_o chap._n 4_o 5_o 6._o or_o ii_o as_o it_o be_v a_o alterative_a of_o the_o blood_n etc._n etc._n which_o be_v all_o improvement_n because_o almost_o whole_o disregard_v and_o never_o bring_v into_o any_o method_n to_o this_o day_n though_o it_o be_v the_o far_o noble_a use_n by_o how_o much_o cure_v excel_v bare_a please_a or_o palliate_a though_o these_o last_o uses_n have_v already_o render_v it_o the_o most_o general_a medicament_n that_o be_v in_o be_v insomuch_o that_o silvius_n say_v have_v only_a respect_n to_o this_o use_n that_o he_o have_v rather_o not_o be_v a_o physician_n than_o not_o know_v the_o use_n of_o opium_n iii_o as_o a_o evacuative_a by_o relax_v and_o open_v the_o pore_n its_o effect_n and_o use_v as_o a_o pleaser_n of_o sensation_n be_v fair_o reducible_a to_o these_o general_a head_n viz._n 1._o it_o be_v comfort_v gratify_a encourage_v and_o invigorate_n of_o the_o sensitive_a soul_n and_o spirit_n 2._o it_o be_v compose_v the_o sensitive_a soul_n spirit_n etc._n etc._n 3._o it_o be_v relax_v all_o the_o senfile_v part_n of_o the_o body_n 4._o it_o be_v cause_v sleep_n 5._o it_o be_v cause_v indolence_n or_o take_v away_o pain_n 6._o it_o be_v stop_v flux_n that_o depend_v upon_o irritation_n grievous_a sensation_n contraction_n etc._n etc._n 7._o its_o promote_a flux_n that_o depend_v upon_o relaxation_n 8._o it_o be_v cause_v titillation_n 9_o it_o be_v cause_v vigilancy_n or_o watch_v in_o some_o person_n its_o effect_n and_o use_v as_o a_o alterative_a be_v 1._o to_o invigorate_v nature_n or_o the_o sensitive_a soul_n and_o spirit_n which_o be_v the_o principle_n of_o all_o motion_n and_o alteration_n for_o the_o preservation_n of_o the_o animal_n 2._o to_o give_v nature_n or_o the_o sensitive_a soul_n a_o euphory_n in_o that_o work_n of_o preservation_n alteration_n etc._n etc._n 3._o to_o administer_v fresh_a and_o most_o agreeable_a principle_n for_o that_o end_n 4._o to_o administer_v such_o as_o be_v more_o vigorous_a and_o powerful_a than_o our_o own_o in_o order_n 5._o to_o resolve_v all_o ill_a humour_n as_o vigorous_a and_o agreeable_a menstrunm_n do_v 6._o to_o compose_v combine_v concentrate_v or_o unite_v the_o good_a and_o agreeable_a part_n of_o those_o humour_n and_o by_o its_o agreeableness_n to_o join_v with_o they_o and_o cause_v a_o strict_a combination_n of_o part_n to_o intercede_v and_o as_o it_o be_v cement_v they_o 7._o to_o discuss_v the_o separate_a and_o effete_a part_n of_o those_o humour_n by_o its_o brisk_a volatile_a salt_n and_o its_o effect_n and_o use_v as_o a_o evacuative_a be_v 1._o to_o cause_v a_o liberal_a perspiration_n to_o give_v those_o effete_a part_n their_o exit_fw-la in_o the_o most_o natural_a plentiful_a kind_a and_o universal_a manner_n 2._o to_o cause_n sweat_n when_o there_o be_v sufficient_a matter_n for_o that_o end_n 3._o to_o relax_v and_o open_v the_o pore_n for_o the_o menses_fw-la and_o lochia_n etc._n etc._n chap._n xxxi_o of_o the_o use_n of_o the_o panacea_fw-la or_o well-prepared_n opiate_n to_o comfort_v and_o invigorate_v the_o sensitive_a soul_n and_o spirit_n i_o have_v show_v how_o and_o why_o it_o cause_v a_o blithe_a gay_a and_o good_a humour_n serenity_n ovation_n of_o the_o sensitive_a soul_n and_o spirit_n alacrity_n promptitude_n assurance_n courage_n magnanimity_n euphory_n or_o easy_a undergo_n of_o labour_n journey_n etc._n etc._n it_o therefore_o follow_v 1._o that_o it_o must_v prevent_v or_o take_v off_o sadness_n melancholy_a cloudiness_n slowness_n dulness_n listlesness_n laziness_n bashfulness_n cowardice_n fear_v pusillanimity_n lassitude_n distress_n anxiety_n solicitude_n and_o all_o such_o grievous_a passion_n as_o wine_n ad_fw-la hilaritatem_fw-la do_v 2._o that_o by_o fortify_v the_o sensitive_a soul_n and_o spirit_n it_o must_v prevent_v contagious_a infection_n and_o mighty_o enable_v and_o invigorate_v nature_n to_o subdue_v and_o conquer_v what_o be_v inimicous_a to_o it_o in_o all_o respect_n 3._o that_o it_o prevent_v and_o take_v off_o faint_n and_o leipothymy_n that_o happen_v from_o the_o aforesaid_a cause_n as_o those_o upon_o fear_n tâ—rour_n hard_a labour_n be_v plague-struck_a and_o the_o like_a i._o the_o form_n that_o it_o be_v to_o be_v give_v in_o be_v indifferent_a unless_o a_o very_a sudden_a effect_n be_v require_v as_o may_v happen_v in_o faint_v fit_n etc._n etc._n for_o then_o as_o be_v say_v a_o liquid_a form_n in_o wine_n or_o hot_a cordial_n be_v best_a ii_o the_o do_v in_o these_o case_n must_v be_v moderate_a and_o sometime_o in_o great_a case_n the_o high_a for_o great_a grievance_n cause_v proportionable_a defensive_a contraction_n which_o oppose_v the_o good_a effect_n of_o the_o panacea_fw-la etc._n etc._n iii_o the_o vehicle_n shall_v be_v a_o glass_n of_o generous_a wine_n cordial_a fermented_a liquor_n comfortable_a spirit_n or_o suchlike_a to_o which_o you_o may_v add_v if_o you_o please_v pleasant_a and_o comfortable_a thing_n as_o tincture_n of_o saffron_n or_o its_o spirit_n chemical_a oil_n as_o of_o cinnamon_n nutmeg_n sassaphras_n cloves_n etc._n etc._n drop_v into_o sugar_n ambergrise_v musk_n etc._n etc._n iv_o the_o time_n of_o give_v it_o be_v at_o such_o a_o convenient_a distance_n before_o the_o time_n that_o you_o will_v have_v it_o operate_v that_o it_o may_v produce_v its_o effect_n at_o the_o time_n desire_v see_v the_o general_n rule_v as_o to_o time_n when_o it_o be_v requisite_a to_o continue_v its_o effect_n as_o in_o long_a journey_n or_o the_o like_a repeat_v it_o as_o soon_o as_o you_o find_v the_o effect_n of_o the_o former_a do_v begin_v sensible_o to_o decay_v because_o it_o take_v some_o time_n to_o operate_v v._o the_o regimen_n when_o action_n or_o business_n be_v intend_v be_v to_o keep_v in_o motion_n discourse_n or_o the_o like_a lest_o you_o sleep_n or_o grow_v drowsy_a but_o when_o you_o intend_v sleep_n observe_v the_o regimen_n direct_v in_o the_o chapter_n of_o its_o use_n to_o cause_v sleep_n though_o less_o sustenance_n will_v serve_v when_o you_o use_v it_o yet_o must_v it_o not_o be_v omit_v in_o a_o moderate_a manner_n the_o kind_a must_v be_v such_o as_o be_v easy_a of_o digestion_n and_o apt_a to_o promote_v perspiration_n as_o light_a bread_n mutton_n lamb_n neat's-tongue_n sweetbread_n and_o lamb-stone_n with_o agreeable_a sauce_n that_o may_v help_v digestion_n and_o perspiration_n which_o be_v a_o great_a cause_n of_o serenity_n and_o alacrity_n as_o sanctorius_n observe_v because_o that_o thereby_o fume_n and_o vapour_n which_o cloud_n and_o clog_v the_o spirit_n be_v evaporate_v and_o the_o spirit_n become_v serene_a and_o expedite_a it_o be_v to_o be_v observe_v that_o parsley_n selery_n onion_n horseradish_n garlic_n and_o such_o warm_a and_o volatile_a plant_n promote_v perspiration_n your_o drink_n shall_v be_v good_a stomach-wine_n or_o wine_n and_o water_n or_o fine_a clear_a drink_n not_o too_o new_a 1._o note_v that_o as_o have_v be_v intimate_v drink_v good_a acceptable_a and_o generous_a wine_n so_o often_o yet_o moderate_o as_o to_o keep_v a_o continual_a sense_n of_o its_o pleasure_n at_o stomach_n be_v the_o best_a substitute_n to_o it_o that_o can_v be_v use_v for_o it_o will_v thereby_o answer_v much_o of_o the_o permanent_a effect_n of_o well-prepared_n opium_n though_o not_o quite_o so_o convenient_a in_o many_o respect_n as_o 1._o because_o it_o must_v be_v so_o often_o repeat_v 2._o because_o its_o effect_n be_v not_o so_o fine_a and_o charm_a 3._o because_o the_o wine_n heat_v more_o 4._o because_o it_o wash_v the_o stomach_n too_o often_o and_o the_o like_a 2._o note_v
that_o when_o people_n be_v in_o a_o untoward_a condition_n or_o as_o they_o call_v it_o out_o of_o sod_n the_o next_o day_n after_o drink_v man_n often_o advise_v take_v the_o hair_n of_o the_o same_o dog_n that_o be_v drink_v some_o of_o the_o same_o wine_n or_o liquor_n it_o be_v best_o for_o they_o to_o use_v it_o as_o i_o just_a now_o direct_v for_o their_o case_n upon_o the_o good_a effect_n of_o the_o wine_n cease_v be_v much_o like_a that_o upon_o the_o go_n off_o of_o the_o operation_n of_o opium_n which_o may_v also_o in_o this_o case_n be_v use_v instead_o of_o wine_n to_o procure_v a_o better_a and_o blither_n condition_n for_o that_o day_n that_o use_v to_o be_v very_o troublesome_a to_o drinker_n 3._o note_v that_o good_a preparation_n of_o opium_n may_v be_v convenient_o use_v to_o horse_n to_o prevent_v their_o be_v tire_v or_o take_v off_o their_o weariness_n and_o cause_v they_o to_o go_v on_o but_o i_o will_v not_o advise_v any_o preparation_n in_o this_o case_n but_o the_o liquid_a panacea_fw-la in_o good_a ale_n or_o beer_n and_o that_o only_a in_o the_o same_o quantity_n as_o be_v use_v to_o man_n till_o far_a experience_n embolden_v the_o practice_n by_o such_o mean_n i_o can_v doubt_v it_o any_o jade_n may_v be_v make_v to_o appear_v lively_a go_v well_o etc._n etc._n chap._n xxxii_o of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o compose_v the_o sensitive_a soul_n spirit_n etc._n etc._n i_o have_v show_v how_o and_o why_o it_o compose_v and_o quiet_v the_o sensitive_a soul_n spirit_n blood_n stomach_n etc._n etc._n and_o by_o that_o mean_n allay_v all_o the_o fury_n commotion_n perturbation_n and_o turbulent_a exorbitance_n thereof_o and_o that_o often_o without_o sleep_n but_o much_o better_a with_o it_o it_o follow_v therefore_o 1._o that_o it_o prevent_v and_o take_v off_o all_o fret_n and_o turbulent_a passion_n of_o the_o sensitive_a soul_n as_o anger_n uneasy_a agitation_n and_o toss_v of_o the_o mind_n peevishness_n fretfulness_n discontent_n disquietude_n dissatisfaction_n murmur_n turmoiling_n and_o vexatious_a thought_n anxiety_n solicitude_n etc._n etc._n and_o all_o the_o evil_a effect_n thereof_o as_o watch_n waste_v of_o spirit_n or_o strength_n lossitude_n hypochondriacal_a melancholy_n cachexy_n scurvy_n etc._n etc._n but_o these_o last_o belong_v most_o proper_o to_o its_o alterative_a faculty_n or_o virtue_n 2._o all_o involuntary_a furious_a agitation_n of_o the_o sensitive_a soul_n and_o spirit_n as_o madness_n more_o especial_o melancholy_a madness_n or_o such_o as_o proceed_v from_o grievous_a thought_n or_o apprehension_n loss_n cross_n despair_n fear_n terror_n or_o the_o like_a but_o they_o be_v not_o so_o good_a in_o merry_a madness_n as_o those_o from_o joy_n venereal_a fury_n and_o suchlike_a which_o answer_v the_o great_a dispute_n about_o opiate_n in_o madness_n delirium_n epileptical_a fit_n convulsion_n general_a and_o particular_a as_o those_o of_o the_o head_n rise_v of_o the_o light_n vomit_n hiccough_n sabbing_n kecking_n convulsive_a asthma_n palpitation_n and_o tremble_n of_o the_o heart_n shake_v and_o shivering_n upon_o fear_n terror_n cold_a pain_n ague-fits_a convulsive_a colick_n hysterick_n fit_v iliack_a passion_n etc._n etc._n 3._o all_o fever_n and_o fret_n of_o humour_n that_o happen_v from_o any_o of_o the_o aforesaid_a cause_n or_o from_o any_o violent_a motion_n voluntary_a or_o involuntary_a as_o labour_n run_v hew_v fight_a or_o any_o vehement_a exercise_n ratling_n toss_n concussion_n in_o coach_n wagon_n boat_n in_o stormy_a wether_n violent_a ride_v etc._n etc._n or_o from_o heat_n of_o fire_n sun_n bath_n hothouse_n bagnio_n crowd_n lie_v too_o many_o in_o one_o bed_n or_o with_o too_o much_o clothes_n or_o from_o grievous_a sensation_n irritation_n or_o pain_n as_o fever_n upon_o inflammation_n abscess_n bubo_n stone_n colic_n cardialgia_n wound_n fracture_n dislocation_n confusion_n amputation_n lithotomy_n paracentesis_n or_o any_o painful_a operation_n of_o the_o noble_a art_n of_o chirurgery_n agony_n or_o pain_n of_o the_o smallpox_n as_o its_o second_o fever_n and_o the_o like_a or_o from_o flux_n as_o tedious_a and_o turbulent_a vomit_n diarrheas_n dysentery_n cholera_n iliack_a passion_n artificial_a purge_v and_o all_o symptomatick_a or_o immaterial_a fever_n whatsoever_o which_o either_o never_o have_v any_o matter_n but_o proceed_v from_o such_o agitate_a cause_n as_o i_o mention_v or_o remain_v as_o some_o do_v after_o the_o grieve_v matter_n be_v carry_v off_o by_o vomit_v purge_v etc._n etc._n i_o forbear_v mention_v pleurisy_n and_o peripneumonia_n among_o the_o fever_n that_o it_o prevent_v or_o take_v off_o because_o there_o be_v great_a dispute_n whether_o opiate_n be_v convenient_a in_o those_o case_n which_o i_o hope_v to_o determine_v unless_o it_o be_v when_o the_o say_v distemper_n be_v come_v to_o that_o pass_n that_o it_o be_v dangerous_a to_o cause_v sleep_n or_o take_v away_o any_o of_o the_o sense_n of_o the_o irritation_n of_o the_o matter_n to_o be_v expectorate_v lest_o it_o shall_v be_v too_o much_o amass_v in_o the_o bronchias_n or_o windpipe_n and_o so_o choke_v the_o person_n i_o see_v no_o cause_n to_o forbid_v they_o any_o more_o than_o sleep_v or_o opiate_n in_o other_o inflammation_n wherein_o they_o be_v high_o beneficial_a to_o give_v ease_n cause_n sleep_n compose_v the_o spirit_n and_o take_v off_o or_o at_o least_o moderate_a the_o fever_n but_o i_o see_v many_o good_a reason_n to_o use_v they_o 1._o because_o as_o a_o sal-volatile-oleosum_a they_o reserate_v and_o resolve_v clammy_a humour_n and_o be_v so_o agreeable_a in_o principle_n as_o menstraums_n shall_v be_v to_o the_o thing_n to_o be_v resolve_v i_o can_v doubt_v but_o red_a poppy_n be_v upon_o experience_n state_v a_o specific_a in_o those_o case_n for_o that_o reason_n 2._o because_o these_o distemper_n as_o hypocrates_n speak_v be_v from_o a_o segregation_n of_o humour_n by_o agitation_n etc._n etc._n and_o opiate_n excellent_a composer_n thereof_o 3._o because_o they_o be_v such_o great_a discusser_n and_o 4._o open_v the_o pore_n to_o let_v the_o discuss_v matter_n quite_o out_o of_o the_o body_n 5._o because_o it_o may_v be_v that_o by_o its_o relaxation_n upon_o such_o resolution_n the_o lodge_v matter_n may_v be_v cause_v to_o flow_v off_o and_o circulate_v again_o and_o so_o be_v gradue_v discuss_v and_o carry_v off_o by_o the_o open_a pore_n 6._o because_o it_o envigorate_v nature_n to_o perform_v those_o thing_n and_o 7._o give_v ease_n and_o recruit_v of_o the_o spirit_n by_o sleep_n so_o that_o all_o thing_n consider_v i_o think_v as_o experience_n assure_v we_o that_o red_a poppy_n or_o opiate_n in_o due_a quantity_n be_v the_o very_o best_a remedy_n that_o can_v be_v use_v hence_o it_o be_v that_o wedelius_n call_v opium_n a_o antipleuritick_n specific_a he_o have_v observe_v as_o i_o and_o other_o have_v do_v that_o the_o whole_a course_n of_o the_o disease_n and_o expectoration_n will_v succeed_v much_o better_a by_o their_o use._n he_o add_v also_o that_o he_o have_v very_o often_o cure_v they_o by_o its_o help_n without_o let_v of_o blood_n which_o be_v a_o infallible_a sign_n of_o their_o good_a effect_n since_o the_o pleurisy_n can_v hardly_o be_v cure_v without_o bleed_v i_o can_v see_v how_o a_o effect_n that_o bear_v such_o analogy_n to_o sleep_n can_v do_v any_o more_o harm_n than_o sleep_n etmuller_n also_o advise_v the_o give_v of_o opiate_n not_o only_o in_o the_o beginning_n but_o also_o during_o the_o increase_n of_o the_o pleurisy_n or_o peripneumoniae_fw-la so_o that_o i_o conclude_v that_o they_o be_v of_o excellent_a use_n in_o those_o disease_n unless_o it_o be_v when_o sleep_n or_o they_o may_v cause_v too_o much_o insensibleness_n of_o the_o bronchias_n and_o so_o retard_v expectoration_n when_o the_o case_n be_v such_o that_o the_o want_v thereof_o may_v endanger_v the_o person_n be_v be_v choke_v we_o have_v also_o many_o history_n of_o person_n cure_v in_o other_o fever_n by_o large_a dose_n of_o opiate_n i_o suppose_v that_o resinous_a opiate_n cause_v vomit_v and_o great_a disturbance_n by_o reason_n of_o ill_a digestion_n in_o those_o case_n may_v be_v one_o great_a cause_n of_o people_n fear_n and_o jeolousy_n in_o give_v opiate_n which_o be_v easy_o prevent_v by_o give_v liquid_a opiate_n void_a of_o any_o resinous_a particle_n as_o the_o liquid_a panacea_fw-la etc._n etc._n 4._o it_o do_v by_o compose_v quiet_v and_o appease_v the_o motion_n and_o perturbation_n of_o the_o blood_n conduce_v much_o to_o the_o stop_n of_o its_o efflux_n in_o hemorrhage_n or_o bleeding_n that_o be_v unnatural_a as_o at_o nose_n in_o spit_v and_o vomit_v of_o blood_n bleed_v at_o the_o hemorrhoid_v in_o dysentery_n piss_v of_o blood_n etc._n etc._n and_o sometime_o in_o profuse_a menses_fw-la when_o they_o happen_v from_o a_o fever_n or_o too_o much_o motion_n of_o the_o blood_n and_o
benefit_n as_o in_o many_o of_o the_o former_a to_o be_v short_a it_o be_v good_a and_o useful_a in_o all_o pain_n and_o grievous_a sensation_n 1._o eecept_n all_o such_o as_o tend_v to_o the_o speedy_a and_o timely_a benefit_n of_o person_n as_o those_o in_a woman_n labour_n grievance_n at_o stomach_n that_o cause_n vomit_v upon_o over-repletion_n or_o by_o reason_n of_o somewhat_o that_o grieve_v and_o be_v not_o convenient_a to_o stay_v at_o stomach_n or_o irritation_n to_o expectorate_v when_o much_o want_v as_o happen_v sometime_o in_o vomicas_fw-la pleurisy_n peripneumonias_n etc._n etc._n or_o such_o as_o irritate_fw-la and_o solicit_v to_o make_v water_n go_v to_o stool_n etc._n etc._n when_o evacuation_n of_o urine_n ordure_n ill_a humour_n etc._n etc._n be_v requisite_a 2._o except_o when_o grievous_a sensation_n be_v necessary_a call_n or_o intimation_n for_o supply_v refreshment_n etc._n etc._n as_o hunger_n thirst_v etc._n etc._n which_o shall_v be_v take_v off_o only_o by_o the_o pleasure_n of_o good_a meat_n and_o drink_v lest_o nature_n be_v defraud_v where_o you_o may_v observe_v a_o inconvenience_n that_o may_v happen_v by_o the_o frequent_a use_n of_o opium_n take_v away_o appetite_n without_o nutriment_n though_o this_o be_v much_o compensated_a by_o the_o relaxation_n and_o recruit_v that_o opiate_n give_v and_o their_o moderate_v the_o expense_n of_o spirit_n by_o take_v of_o contraction_n and_o may_v more_o if_o not_o whole_o by_o a_o regular_a and_o constant_a way_n of_o eat_v and_o drink_v temperate_o at_o usual_a time_n though_o the_o hunger_n may_v not_o by_o reason_n of_o the_o opiate_n be_v so_o great_a as_o at_o other_o time_n i._o the_o form_n be_v indifferent_a and_o to_o be_v order_v only_o according_a to_o the_o general_a rule_n remember_v that_o the_o liquid_a be_v best_a for_o speed_n ii_o the_o dose_n must_v be_v proportion_v to_o the_o pain_n or_o grievous_a sensation_n and_o always_o rather_o more_o than_o when_o there_o be_v no_o pain_n because_o its_o contraction_n oppose_v the_o relaxation_n to_o be_v induce_v by_o the_o opiate_n observe_v this_o method_n first_o give_v a_o good_a do_v then_o stay_v about_o 2_o or_o 3_o hour_n and_o if_o the_o pain_n be_v not_o at_o all_o lessen_v you_o may_v safe_o then_o give_v half_a the_o quantity_n again_o and_o afterward_o about_o a_o three_o part_n of_o the_o do_v every_o 2_o or_o 3_o hour_n till_o it_o begin_v to_o abate_v but_o upon_o the_o least_o sensible_a abatement_n you_o must_v forbear_v to_o give_v any_o more_o because_o that_o which_o do_v in_o some_o measure_n abate_v the_o pain_n do_v in_o the_o same_o proportion_n abate_v the_o contraction_n and_o consequent_o it_o have_v less_o to_o contest_v with_o therefore_o will_v be_v sure_a to_o conquer_v it_o for_o the_o same_o power_n that_o can_v subdue_v ten_o in_o some_o measure_n will_v subdue_v nine_o in_o a_o great_a measure_n and_o eight_o more_o easy_o than_o nine_o etc._n etc._n till_o the_o pain_n quite_o cease_v whereas_o if_o you_o add_v more_o power_n to_o the_o opiate_n it_o may_v be_v too_o much_o especial_o when_o the_o pain_n be_v thereby_o conquer_v and_o that_o it_o have_v no_o contraction_n to_o contest_v with_o for_o than_o it_o will_v be_v as_o if_o a_o great_a do_v be_v give_v to_o one_o that_o have_v no_o pain_n but_o if_o the_o pain_n increase_v again_o you_o may_v safe_o repeat_v the_o half_n do_v etc._n etc._n every_o 2_o or_o 3_o hour_n till_o it_o again_o begin_v to_o abate_v and_o no_o long_o which_o you_o have_v better_o observe_v to_o do_v as_o soon_o as_o ever_o the_o pain_n begin_v to_o return_v because_o it_o take_v some_o time_n to_o operate_v it_o sollow_v then_o that_o the_o liquid_a form_n be_v most_o convenient_a in_o this_o case_n for_o expedition_n my_o particular_a and_o effectual_a manner_n of_o use_v it_o in_o the_o gout_n will_v be_v somewhat_o too_o redious_a to_o be_v set_v down_o therefore_o since_o it_o may_v be_v obvious_a enough_o to_o the_o sagacious_a that_o consider_v what_o have_v be_v say_v and_o the_o nature_n of_o the_o distemper_n i_o will_v pass_v that_o by_o at_o this_o time_n iii_o the_o vehicle_n in_o cold_a stomach_n and_o constitution_n may_v be_v a_o glass_n of_o wine_n or_o some_o temperate_a cordial_n but_o in_o hot_a case_n or_o where_o a_o fever_n be_v fear_v emulsion_n milk_n and_o water_n or_o water_n alone_o or_o other_o acceptable_a cool_a thing_n or_o such_o as_o be_v direct_v in_o the_o case_n of_o procure_v relaxation_n in_o the_o last_o chapter_n because_o it_o be_v relaxation_n that_o take_v away_o pain_n as_o have_v be_v mechanical_o demonstrate_v but_o heâ—e_v there_o be_v no_o need_n of_o be_v scrupulous_a as_o to_o the_o vehicle_n unless_o it_o be_v in_o respect_n of_o heat_n and_o cold_a as_o the_o case_n happen_v iv_o the_o time_n may_v be_v any_o hour_n as_o the_o case_n require_v only_o remember_v that_o sleep_n conduce_v much_o to_o relaxation_n and_o therefore_o to_o the_o take_v away_o of_o pain_n v._o the_o regimen_n to_o be_v use_v in_o the_o case_n of_o relax_v in_o the_o last_o chapter_n will_v suffice_v but_o it_o be_v convenient_a as_o be_v say_v to_o regard_v the_o stomach_n and_o hot_a and_o cold_a constitution_n especial_o where_o there_o be_v any_o fear_n of_o fever_n by_o give_v cool_a liquid_n as_o emulsion_n etc._n etc._n and_o avoid_v hot_a or_o solid_a thing_n especial_o such_o as_o be_v hard_a of_o digestion_n as_o flâ—sh_v fish_n egg_n etc._n etc._n 1._o note_v that_o it_o be_v very_o advisable_v not_o to_o defer_v the_o use_n of_o opiate_n too_o long_o till_o people_n be_v very_o weak_a though_o it_o may_v seem_v that_o they_o will_v hinder_v some_o due_a evacuation_n for_o i_o can_v see_v what_o harm_n a_o refreshment_n by_o they_o may_v do_v any_o more_o than_o by_o sleep_n both_o depend_v upon_o the_o same_o cause_n viz._n relaxation_n it_o be_v true_a that_o by_o reason_n of_o sleep_n or_o a_o opiate_n the_o evacuation_n may_v be_v a_o little_a defer_v what_o then_o will_v any_o man_n deny_v sleep_n for_o that_o reason_n why_o then_o shall_v a_o physician_n deny_v a_o opiate_n to_o cause_v it_o respite_n nature_n and_o enable_v it_o to_o bear_v its_o burden_n or_o engage_v with_o difficulty_n the_o better_a 2._o remember_v always_o that_o sleep_n be_v a_o great_a help_n to_o take_v away_o pain_n and_o so_o be_v all_o thing_n that_o conduce_v to_o relaxation_n or_o pleasant_a diversion_n 3._o use_v means_n in_o pain_n of_o the_o hemorrhoid_v furdament_n or_o intestinum_fw-la rectum_fw-la and_o indeed_o in_o any_o pain_n within_o the_o gut_n unless_o it_o proceed_v from_o a_o looseness_n that_o opiate_n may_v not_o bind_v man_n too_o much_o as_o leâ—itives_n internal_o or_o emollient_a 〈◊〉_d or_o which_o of_o they_o may_v be_v most_o easy_o and_o convenient_o do_v and_o most_o to_o the_o purpose_n chap._n xxxv_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o cause_n sleep_n it_o primary_o cause_n sleep_v by_o relax_v and_o compose_v quiet_v soothe_v please_a and_o lull_v the_o sensitive_a soul_n and_o spirit_n it_o always_o relax_n but_o do_v not_o always_o sufficient_o compose_v or_o quiet_v the_o spirit_n to_o cause_n sleep_n to_o which_o both_o be_v requisite_a secundary_o by_o take_v away_o grievous_a passion_n or_o sensation_n when_o they_o happen_v to_o hinder_v it_o 1._o as_o soporiserous_a it_o be_v of_o incomparable_a use_n in_o all_o troublesome_a watch_n whether_o they_o be_v from_o grievous_a passion_n or_o sensation_n or_o irrequiete_a motion_n of_o the_o spirit_n though_o not_o so_o certain_a in_o this_o last_o case_n as_o in_o the_o former_a and_o therefore_o prove_v sometime_o unsuccessful_a in_o some_o person_n and_o in_o some_o sort_n of_o madness_n as_o the_o merry_a or_o furicus_n though_o it_o be_v effectual_a in_o melancholy_n and_o slow_a manias_fw-la as_o have_v be_v intimate_v for_o bare_a relaxation_n suffice_v in_o the_o two_o first_o case_n where_o sleep_n be_v hinder_v by_o contraction_n which_o it_o never_o fail_v to_o take_v off_o if_o give_v in_o a_o due_a quantity_n as_o have_v be_v direct_v 2._o to_o recruit_v the_o spirit_n as_o when_o people_n be_v tire_v with_o labour_n journey_n disease_n conflict_n of_o nature_n as_o by_o convulsion_n vomit_n purge_n hysteric_a fit_n and_o the_o like_a 3._o to_o relax_v compose_v take_v away_o pain_n moderate_a flux_n that_o depend_v upon_o grievous_a sensation_n or_o irritation_n and_o its_o consequent_a contraction_n or_o from_o motion_n or_o segregation_n of_o humour_n 4._o to_o promote_v flux_n that_o depend_v upon_o relaxation_n as_o perspiration_n sweat_v as_o also_o the_o menses_fw-la and_o lochia_n in_o some_o case_n of_o all_o which_o you_o have_v particular_a chapter_n which_o see_v i._o the_o form_n may_v be_v indifferent_o either_o solid_a or_o liquid_a as_o
it_o be_v best_o like_v and_o most_o suitable_a to_o people_n mind_n palate_n etc._n etc._n ii_o the_o do_v moderate_a except_o it_o be_v 1._o where_o some_o by_o accident_n require_v otherwise_o as_o pain_n looseness_n vomit_n and_o to_o titillate_v the_o venereal_a membrane_n because_o remote_a which_o see_v in_o the_o respective_a chapter_n of_o the_o use_n of_o opiate_n in_o those_o case_n 2._o where_o the_o general_a rule_n direct_v otherwise_o as_o in_o the_o soft_a flesh_a people_n child_n woman_n etc._n etc._n where_o the_o do_v must_v be_v less_o iii_o the_o vehicle_n must_v be_v the_o same_o as_o be_v direct_v to_o compose_v but_o in_o old_a people_n it_o be_v observe_v that_o smooth_a spirituous_a thing_n as_o good_a ale_n etc._n etc._n conduce_v very_o much_o to_o cause_v sleep_n because_o sulphur_n do_v qualifie-the_a volatile_a salt_n of_o the_o opium_n as_o be_v show_v iv_o the_o time_n in_o general_n be_v at_o the_o due_a distance_n before_o bedtime_n that_o be_v direct_v in_o the_o general_a rule_n but_o opiate_n may_v be_v give_v at_o any_o time_n when_o the_o case_n require_v as_o in_o the_o smallpox_n about_o 12_o 1_o or_o 2_o in_o the_o afternoon_n according_a as_o the_o â—tions_n which_o happen_v in_o the_o afternoon_n or_o towards_o the_o evening_n do_v seize_v they_o and_o in_o ague_n at_o the_o due_a distance_n before_o the_o paroxysm_n invade_v they_o 〈◊〉_d that_o the_o operation_n thereof_o may_v be_v fall_n and_o complete_a before_o the_o time_n that_o the_o fit_n be_v to_o begin_v and_o so_o in_o all_o other_o câ—ses_n of_o the_o like_a â—ind_n v._o the_o regimen_n in_o this_o 〈◊〉_d 〈◊〉_d 〈◊〉_d twosold_a aspect_n 1._o to_o promote_v 〈◊〉_d 2._o to_o compose_v and_o quiet_a motion_n 〈◊〉_d â—tions_n of_o the_o spirit_n 〈◊〉_d etc._n etc._n 〈◊〉_d 〈◊〉_d quiet_v be_v the_o two_o 〈◊〉_d 〈◊〉_d as_o to_o the_o first_o the_o regimen_n must_v be_v the_o same_o as_o be_v direct_v in_o the_o chapter_n of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o relax_v but_o as_o to_o compose_v and_o quiet_v the_o spirit_n i_o shall_v add_v somewhat_o though_o relaxer_n be_v general_o good_a for_o this_o purpose_n unless_o join_v with_o some_o agitate_v accident_n as_o heat_n or_o the_o like_a 1._o as_o to_o diet_n it_o shall_v consist_v of_o cool_a incrassate_a inviscate_a thing_n that_o be_v not_o aromatic_a acid_a or_o saline_a such_o be_v milk-meat_n emulsion_n almond_n milks_n chicken_n broth_n with_o cool_a herb_n water-gruel_n fresh_a and_o young_a soft_a flesh_n lettuce_n purstane_n spinage_n herb_n mercury_n mallow_n and_o such_o like_a mucilage_n as_o of_o quince_n fleabane_n etc._n etc._n the_o drink_n may_v be_v milk_n and_o water_n whey_n or_o such_o unfermented_a liquor_n or_o smooth_a small_a beer_n not_o too_o old_a for_o all_o stale_a drink_n be_v naught_o water_n where_o it_o agree_v etc._n etc._n 2._o rest_v of_o body_n and_o spirit_n must_v be_v contrive_v by_o all_o mean_n as_o by_o lean_v lie_a or_o sit_v still_o without_o any_o motion_n after_o it_o be_v take_v till_o bedtime_n and_o therefore_o let_v the_o person_n if_o the_o season_n permit_v be_v as_o much_o undress_v as_o may_v be_v in_o a_o loose_a garment_n or_o morning-gown_n all_o that_o time_n and_o be_v help_v off_o with_o his_o clothes_n that_o he_o may_v not_o agitate_v his_o body_n when_o sleepy_a and_o not_o before_o let_v he_o go_v into_o a_o cold_a bed_n in_o summer_n and_o but_o a_o little_a warm_v in_o winter_n and_o only_o have_v what_o bedclothe_n suffice_v and_o please_v he_o best_o and_o then_o lie_v absolute_o still_o without_o noise_n light_z or_o fire_n in_o the_o room_n 3._o rest_v and_o tranquillity_n of_o mind_n be_v very_o necessary_a which_o shall_v be_v not_o only_o free_a from_o grievous_a passion_n but_o from_o all_o excess_n of_o joyous_a one_o which_o too_o much_o agitate_v the_o spirit_n 4._o the_o air_n shall_v be_v moist_a and_o moderate_a and_o if_o not_o such_o by_o the_o wether_n render_v so_o by_o art_n especial_o in_o fever_n 5._o all_o evacuation_n shall_v be_v make_v that_o may_v any_o way_n disturb_v his_o sleep_n before_o he_o betake_v himself_o to_o it_o nor_o shall_v the_o stomach_n be_v over-full_a or_o empty_a lest_o any_o grievance_n may_v be_v thereby_o create_v 6._o emollient_a tepid_a bath_n fomentation_n feetwash_n etc._n etc._n do_v fine_o dispose_v people_n to_o sleep_n but_o take_v care_n they_o be_v not_o too_o hot_a for_o heat_n cause_v a_o stir_n of_o blood_n and_o spirit_n which_o be_v a_o enemy_n to_o sleep_n 1._o note_v that_o long_o sleep_v after_o great_a fatigue_n or_o long_o watch_v ought_v not_o to_o be_v very_o frightful_a if_o the_o do_v be_v moderate_a and_o that_o the_o person_n take_v sustenance_n 2._o note_v that_o old_a or_o dry_a person_n or_o such_o as_o be_v very_o unapt_a to_o sleep_v after_o opiate_n be_v often_o cause_v to_o sleep_v by_o smooth_a wine_n ale_z cowslip_n wine_n or_o the_o like_a because_o the_o gentle_a oiliness_n of_o such_o liquor_n do_v correct_v the_o acrimony_n of_o their_o volatile_a salt_n and_o at_o the_o same_o time_n cause_n a_o sense_n of_o pleasure_n which_o relax_n and_o cause_n sleep_v it_o have_v be_v observe_v that_o even_o ambergrise_v and_o musk_n which_o exagitate_v the_o blood_n and_o spirit_n cause_v old_a man_n to_o sleep_n which_o happen_v by_o their_o fine_a sulphur_n ready_o fasten_v upon_o the_o acrimonious_a volatile_a salt_n as_o spirit_n of_o wine_n do_v upon_o sal_fw-la ammoniac_a which_o be_v mix_v do_v soon_o coagulate_v therefore_o i_o be_o apt_a to_o think_v that_o camphire_n will_v be_v of_o excellent_a use_n to_o correct_v the_o opium_n and_o the_o volatile_a salt_n of_o the_o body_n in_o such_o case_n because_o it_o be_v experimental_o certain_a that_o it_o correct_v the_o acrimony_n of_o urine_n of_o semen_n virile_a cantharides_n etc._n etc._n 3._o note_v that_o the_o dry_a the_o body_n be_v the_o more_o unapt_a be_v opiate_n to_o cause_n sleep_n therefore_o dry_a body_n as_o of_o old_a man_n hectical_a person_n etc._n etc._n shall_v be_v well_o moisten_v by_o incrassative_a moistener_n as_o emulsion_n and_o such_o thing_n as_o be_v above_o mention_v and_o order_v in_o the_o chapter_n of_o the_o relax_a use_n of_o opiate_n from_o what_o be_v say_v i_o do_v conclude_v that_o opiate_n do_v cause_n sleep_v very_o ready_o where_o the_o oily_a part_n abound_v and_o that_o thing_n that_o have_v a_o fine_a oleous_a sulphur_n be_v very_o good_a corrector_n of_o it_o where_o acrimonious_a volatile_a salt_n abound_v in_o order_n to_o cause_n sleep_n and_o that_o hence_o it_o be_v that_o some_o ancient_a people_n will_v often_o sleep_v better_o by_o the_o use_n of_o the_o aforementioned_a smooth_a ferment_v sulphureous_a liquor_n than_o by_o the_o use_n of_o opium_n from_o all_o which_o it_o appear_v that_o sleep_n be_v not_o such_o a_o property_n of_o opium_n as_o people_n make_v it_o to_o be_v because_o that_o beside_o relax_v sleep_v also_o require_v a_o great_a rest_n of_o the_o spirit_n and_o the_o sensitive_a soul_n it_o seem_v very_o probable_a from_o the_o premise_n that_o anodyne_n sulphur_n of_o vitriol_n will_v be_v excellent_a to_o cause_v old_a man_n to_o sleep_n for_o it_o doubtless_o cause_n sleep_v only_o by_o obtund_v and_o qualify_a our_o volatile_a salt_n as_o white_a 〈◊〉_d and_o other_o balsamicks_n will_v often_o do_v chap._n xxxvi_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o stop_v flux_n it_o palliate_v moderate_v and_o stop_v flux_n 1._o by_o take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o cause_n contraction_n to_o squeeze_v they_o out_o and_o promote_v their_o motion_n 2._o because_o it_o compose_v and_o still_v the_o motion_n of_o humour_n by_o the_o relaxation_n and_o the_o sleep_n that_o it_o cause_n which_o quiet_v motion_n 3._o because_o thereby_o and_o by_o its_o combine_a agreeableness_n and_o texture_n it_o congregate_n the_o disgregated_a humour_n 4._o because_o the_o relaxation_n suspend_v the_o humour_n 5._o because_o it_o discuss_n ill_a humour_n 6._o because_o the_o pore_n be_v open_v by_o the_o relaxation_n the_o humour_n that_o cause_v the_o flux_n be_v gradual_o perspire_v by_o that_o most_o natural_a and_o universal_a sort_n of_o evacuation_n for_o it_o be_v plain_a reason_n and_o common_a observation_n that_o a_o plentiful_a evacuation_n at_o pore_n stop_v flux_n per_fw-la anum_fw-la etc._n etc._n and_o if_o it_o continue_v perfect_o cure_v they_o ☞_o hence_o it_o be_v that_o the_o use_v of_o opiate_n continue_v do_v happy_o not_o only_o palliate_v but_o perfect_o cure_v diarrheas_n dysentery_n defluxion_n catarrh_n etc._n etc._n it_o therefore_o follow_v that_o it_o be_v of_o great_a use_n 1._o to_o palliate_v moderate_a or_o cure_v all_o flux_n that_o proceed_v from_o irritation_n of_o humour_n as_o vomit_n
nothing_o more_o sure_a than_o that_o it_o have_v such_o a_o effect_n if_o the_o do_v be_v large_a enough_o and_o that_o most_o of_o the_o eastern_a nation_n use_v it_o for_o that_o end_n with_o infallible_a effect_n iii_o the_o time_n shall_v be_v 5_o or_o 6_o hour_n before_o the_o effect_n be_v expect_v or_o at_o bedtime_n to_o cause_v its_o effect_n towards_o the_o morning_n particular_o in_o the_o case_n of_o exciting_a to_o venery_n iv_o the_o regimen_n as_o to_o diet_n it_o must_v be_v nourish_v warm_a comfort_a and_o titillate_v with_o realish_v and_o high_a sauce_n oyster_n anchovy_n caviar_n cockle_n ketchup_o mango_n garlic_n onion_n leek_n bear_v garlic_n rocket_n sives_z shelot_n ginger_n aromatics_n roâ—ts_n of_o satyrion_n feaverfew_n goatsbeard_n silver-weed_n skirret_n parsnip_n and_o artichoke_n the_o use_n of_o ambergrise_n musk_n and_o civet_n be_v commend_v but_o good_a stomach-wine_n and_o thâ—_n like_a be_v certain_o of_o use_n sine_fw-la baccho_fw-la friget_fw-la venus_n but_o it_o be_v certain_a that_o camphire_n and_o sulphureous_a thing_n unferment_v as_o oil_n rosin_n and_o fat_a thing_n oppose_v titillation_n as_o do_v also_o slimy_a mucilaginous_a and_o cool_a thing_n chap._n thirty-nine_o of_o the_o use_n of_o the_o panacea_fw-la of_o opium_n etc._n etc._n to_o cause_n watch_v i_o have_v show_v how_o opiate_n cause_v watch_v in_o some_o person_n by_o reason_n of_o the_o over-agitating_a and_o actuate_a the_o spirit_n and_o titillate_v by_o its_o volatile_a salt_n yet_o do_v they_o by_o cause_v pleasure_n and_o relaxation_n support_v the_o spirit_n while_o the_o extraordinary_a ovation_n of_o they_o hinder_v sleep_n therefore_o it_o be_v of_o use_n to_o such_o as_o it_o cause_v watch_v to_o when_o it_o be_v requisite_a for_o they_o to_o watch_v about_o any_o business_n labour_n journey_n etc._n etc._n i._o the_o form_n may_v be_v either_o solid_a or_o liquid_a ii_o the_o do_v moderate_a iii_o the_o vehicle_n shall_v be_v acid_n or_o other_o liquid_n with_o volatile_a salt_n iv_o the_o time_n may_v be_v at_o any_o hour_n when_o want_v v._o the_o regimen_n quite_o contrary_a to_o that_o of_o sleep_n and_o relaxation_n viz._n to_o use_v voluntary_a motion_n etc._n etc._n chap._n xl._n of_o the_o alterative_a use_n of_o the_o panacea_fw-la of_o opium_n you_o see_v the_o mighty_a extent_n and_o general_n use_v of_o the_o panacea_fw-la of_o opium_n as_o a_o pleaser_n of_o sensation_n which_o take_v up_o the_o nine_o last_o chapter_n to_o mention_v the_o head_n of_o its_o performance_n without_o descend_v into_o all_o particular_n because_o their_o number_n be_v indefinite_a how_o universal_a then_o must_v its_o use_n be_v when_o we_o add_v thereto_o its_o effect_n as_o a_o consummate_a alterative_a which_o 1._o invigorates_n nature_n by_o comfort_v the_o sublimest_n principles_n thereof_o viz._n the_o sensitive_a soul_n and_o spirit_n that_o be_v the_o original_a of_o all_o motion_n and_o action_n 2._o furnish_v they_o with_o a_o indefatigable_a euphory_n in_o the_o great_a business_n of_o our_o preservation_n 3._o put_v the_o best_a mean_n into_o the_o hand_n of_o invigorated_a nature_n for_o that_o end_n that_o be_v most_o agreeable_a principle_n even_o more_o powerful_a and_o of_o a_o great_a energy_n than_o our_o own_o which_o must_v as_o agreeable_a and_o exalt_a menstruum_n do_v resolve_v all_o humour_n congregate_a the_o good_a and_o homogeneous_a and_o separate_v the_o effete_a and_o heterogeneous_a part_n which_o it_o 4._o discuss_n and_o dissipate_v by_o its_o brisk_a and_o active_a volatile_a salt_n and_o at_o last_o 5._o convey_v out_o of_o the_o body_n by_o a_o liberal_a perspiration_n the_o most_o natural_a universal_a and_o copious_a way_n of_o evacuation_n all_o which_o be_v consider_v it_o be_v i_o think_v manifest_a that_o it_o must_v excel_v all_o other_o panaceas_fw-la 1._o because_o it_o take_v away_o the_o grievance_n or_o form_n of_o disease_n upon_o the_o very_a first_o administration_n thereof_o whereas_o other_o medicament_n do_v that_o but_o gradual_o as_o they_o alter_v or_o subdue_v the_o matter_n 2._o because_o it_o high_o comfort_v nature_n or_o the_o sensitive_a soul_n and_o spirit_n from_o the_o very_a commencement_n of_o the_o cure_n and_o through_o the_o whole_a process_n thereof_o if_o due_o repeat_v which_o other_o medicament_n do_v only_o by_o insensible_a degree_n as_o they_o gain_v upon_o the_o disease_n 3._o because_o it_o procure_v sleep_n the_o sweet_a and_o chief_a refreshment_n of_o and_o first_o cure_n in_o nature_n so_o that_o i_o can_v see_v what_o can_v be_v desire_v in_o a_o medicament_n that_o it_o be_v not_o accomplish_v with_o whereas_o other_o panaceas_fw-la be_v deficient_a or_o at_o least_o come_v very_o short_a of_o we_o in_o these_o extraordinary_a qualification_n which_o seem_v to_o make_v it_o absolute_o complete_a and_o consummate_a 4._o because_o it_o from_o the_o very_a first_o compose_v all_o perturbation_n and_o enormous_a motion_n of_o the_o sensitive_a soul_n or_o â—_z which_o helmont_n attribute_n to_o the_o archaeus_n place_v all_o disease_n therein_o and_o therefore_o say_v ort._n imag._n mâ—rb_n sect._n 12._o universal_a quoddam_fw-la arcanum_fw-la consopotivum_fw-la &_o sedativum_fw-la archaei_n est_fw-la adhibendum_fw-la that_o be_v a_o universal_a remedy_n that_o appease_v the_o archaeus_n shall_v be_v use_v and_o what_o appease_v or_o compose_v it_o more_o than_o or_o as_o much_o as_o opiate_n therefore_o i_o can_v wonder_v that_o paracelsus_n shall_v declare_v that_o it_o serve_v his_o purpose_n when_o all_o his_o arcanas_fw-la sail_v or_o that_o helmont_n shall_v be_v in_o a_o rapture_n upon_o the_o apprehension_n of_o the_o excellency_n of_o opium_n if_o the_o noxious_a quality_n be_v separate_v from_o it_o though_o he_o have_v a_o very_a wrong_a notion_n of_o its_o operation_n as_o appear_v potest_fw-la medicam_fw-la sect._n 4._o where_o he_o say_v that_o opium_n archaeum_n abigit_fw-la &_o fugat_fw-la that_o be_v opium_n chase_v and_o put_v the_o archaeus_n to_o flight_n which_o on_o the_o contrary_a it_o high_o please_v and_o comfort_n it_o be_v endless_a and_o a_o kind_a of_o impertinence_n to_o descend_v into_o particular_n in_o the_o use_n of_o a_o panacea_fw-la therefore_o have_v show_v how_o it_o operate_v by_o invigorate_n nature_n cause_v euphory_n ease_n sleep_v resolve_v all_o humour_n as_o a_o general_a menstruum_fw-la or_o alkahe_a congregate_a the_o good_a separate_a discuss_v and_o carry_v off_o the_o bad_a particle_n etc._n etc._n it_o remain_v only_o that_o i_o show_v you_o how_o to_o use_v it_o as_o to_o form_n do_v etc._n etc._n leave_v the_o administration_n thereof_o in_o particular_a case_n to_o physician_n therein_o concern_v i._o the_o form_n that_o i_o main_o approve_v of_o to_o alter_v be_v the_o liquid_a because_o the_o solid_a be_v in_o some_o measure_n though_o not_o much_o impair_v by_o the_o evaporation_n to_o the_o due_a consistence_n and_o do_v not_o consist_v of_o the_o fine_a part_n as_o the_o liquid_a do_v ii_o the_o dose_n may_v be_v at_o first_o about_o 20_o drop_n add_v a_o drop_n to_o every_o do_v till_o the_o distemper_n be_v in_o good_a measure_n abate_v then_o let_v the_o same_o number_n of_o drop_n be_v continue_v till_o the_o person_n be_v well_o and_o afterward_o abate_v by_o a_o drop_v every_o day_n till_o you_o come_v to_o ten_o or_o less_o or_o to_o such_o a_o inconsiderable_a do_v that_o you_o can_v find_v no_o effect_n at_o all_o note_v that_o though_o i_o be_o cautious_a in_o the_o dose_v till_o trusty_a experience_n give_v more_o assurance_n yet_o do_v i_o believe_v that_o no_o inconvenience_n will_v be_v find_v by_o far_o great_a dose_n if_o by_o any_o unless_o very_o excessive_a as_o 1_o or_o 2_o gallon_n of_o wine_n be_v in_o respéct_n of_o a_o pint_n which_o in_o such_o dose_n may_v be_v and_o be_v injurious_a such_o as_o have_v pain_n to_o be_v take_v off_o must_v use_v it_o as_o be_v direct_v in_o the_o chapter_n of_o its_o use_n to_o take_v away_o pain_n gradual_o increase_a so_o as_o to_o keep_v it_o off_o and_o when_o the_o cure_n be_v in_o great_a measure_n perform_v must_v continue_v and_o decrease_v as_o be_v aforesaid_a the_o like_a be_v to_o be_v say_v as_o to_o flux_n etc._n etc._n iii_o the_o vehicle_n may_v be_v in_o general_a plain_a water_n or_o rather_o alter_v and_o make_v bitter_a by_o a_o infusion_n of_o the_o ingredient_n of_o the_o bitter_a decoction_n or_o agrimony_n wood-sage_a bean_n trefoil_n or_o the_o like_a good_a bitter_a thing_n that_o be_v know_v by_o experience_n to_o cause_v a_o good_a digestion_n in_o particular_a case_n the_o vehicle_n may_v be_v appropriate_v to_o the_o disease_n yet_o always_o so_o order_v it_o that_o it_o may_v be_v stomachical_a iv_o the_o time_n shall_v general_o be_v in_o the_o morning_n unless_o sleep_v at_o night_n be_v to_o be_v procure_v thereby_o if_o so_o you_o must_v order_v thing_n as_o in_o the_o