say_v unferment_v succus_fw-la nutritius_n which_o liquor_n thus_o compound_v and_o prepare_v be_v drive_v by_o a_o succession_n of_o matter_n through_o its_o proper_a passage_n into_o the_o cavity_n of_o the_o fibrous_a cell_n the_o remain_v and_o more_o crude_a part_n of_o the_o succus_fw-la nutritius_n be_v receive_v together_o with_o the_o blood_n and_o carry_v back_o to_o the_o heart_n this_o liquor_n after_o this_o manner_n convey_v to_o the_o cavity_n of_o the_o fiber_n it_o do_v as_o it_o pass_v and_o be_v thrust_v through_o according_a to_o the_o continual_a law_n of_o circulation_n give_v nourishment_n to_o the_o part_n and_o be_v thence_o receive_v by_o the_o lymphduct_n thus_o i_o conceive_v it_o be_v continual_o prepare_v in_o the_o glandule_n and_o circulate_v through_o the_o carnous_a fiber_n of_o all_o the_o part_n of_o the_o body_n whilst_o motion_n cease_v in_o a_o moderate_a quantity_n so_o that_o the_o lymphduct_n be_v capable_a of_o receive_v it_o and_o thereby_o prevent_v the_o preternatural_a repletion_n of_o the_o fiber_n to_o prove_v what_o i_o have_v hitherto_o say_v beside_o the_o verisimilitude_n the_o thing_n carry_v with_o it_o i_o can_v bring_v many_o argument_n to_o illustrate_v and_o to_o make_v it_o appear_v more_o plausible_a and_o evident_a but_o for_o brevity_n sake_n and_o to_o prevent_v unnecessary_a repetition_n i_o shall_v omit_v they_o here_o because_o they_o be_v to_o be_v mention_v hereafter_o i_o have_v give_v a_o brief_a account_n of_o the_o structure_n of_o a_o muscle_n as_o far_o as_o relate_v to_o my_o hypothesis_n and_o the_o use_v of_o the_o part_n as_o they_o serve_v to_o nutrition_n i_o now_o proceed_v to_o the_o efficient_a cause_n of_o muscular_a motion_n both_o voluntary_a and_o involuntary_a and_o first_o of_o the_o reason_n of_o voluntary_a motion_n that_o voluntary_a motion_n do_v depend_v upon_o the_o dictate_v of_o the_o soul_n and_o be_v the_o result_n of_o its_o faculty_n but_o more_o immediate_o of_o our_o appetite_n be_v sufficient_o evince_v because_o it_o be_v instant_o perform_v according_a to_o our_o will._n where_o the_o soul_n be_v lodge_v how_o and_o after_o what_o manner_n it_o operate_v and_o what_o it_o be_v be_v most_o difficult_a to_o determine_v and_o be_v not_o design_v for_o our_o present_a enquiry_n but_o as_o it_o come_v under_o the_o consideration_n of_o the_o brain_n and_o its_o appendage_n i_o shall_v defer_v my_o thought_n of_o that_o till_o i_o have_v a_o further_a opportunity_n in_o the_o mean_a time_n that_o neither_o the_o soul_n nor_o any_o of_o its_o faculty_n be_v the_o immediate_a cause_n of_o muscular_a motion_n but_o operate_v by_o the_o mediation_n of_o the_o animal_n spirit_n will_v appear_v from_o what_o follow_v concern_v the_o reason_n of_o voluntary_a motion_n and_o that_o the_o office_n of_o the_o will_n be_v only_o to_o open_v and_o shut_v the_o pore_n of_o the_o brain_n by_o a_o organical_a motion_n as_o necessity_n require_v what_o this_o motion_n be_v and_o how_o it_o be_v perform_v and_o after_o what_o manner_n the_o dictate_v of_o the_o soul_n and_o of_o its_o faculty_n be_v put_v in_o action_n be_v reserve_v for_o its_o proper_a seat_n after_o what_o manner_n soever_o the_o soul_n exert_v its_o faculty_n and_o direct_v that_o subtle_a matter_n the_o animal_n spirit_n which_o be_v send_v through_o the_o branch_n of_o the_o nerve_n in_o great_a or_o less_o quatity_n according_a to_o our_o appetite_n to_o this_o or_o that_o part_n it_o be_v allow_v that_o when_o our_o body_n cease_v from_o motion_n and_o all_o our_o voluntary_a faculty_n be_v at_o quiet_a the_o pore_n and_o passage_n of_o the_o brain_n lead_v to_o the_o instrument_n of_o voluntary_a motion_n be_v lock_v or_o close_v up_o and_o then_o i_o suppose_v that_o the_o spirit_n moderate_o flow_v into_o each_o muscle_n do_v prepare_v so_o much_o of_o the_o subtle_a liquor_n aforementioned_a as_o be_v sufficient_a to_o nourish_v the_o part_n as_o it_o pass_v through_o '_o they_o but_o when_o the_o pore_n of_o the_o brain_n be_v open_v motion_n and_o unlock_v the_o animal_n spirit_n force_v by_o a_o continual_a succession_n of_o matter_n flow_v into_o all_o the_o branch_n of_o the_o nerve_n more_o plentiful_o and_o be_v lay_v down_o in_o the_o glandule_n raise_v a_o strong_a fermentation_n by_o which_o mean_v a_o great_a quantity_n of_o the_o subtle_a liquor_n be_v prepare_v and_o force_v into_o the_o fleshy_a fiber_n more_o copious_o and_o rather_o fast_o that_o it_o can_v be_v receive_v and_o evacuate_v by_o the_o lymphduct_n so_o that_o the_o fiber_n be_v all_o equal_o swell_v with_o its_o quantity_n consequent_o contract_v the_o muscle_n which_o be_v the_o cause_n of_o a_o tonick_n motion_n when_o these_o animal_n spirit_n be_v by_o a_o pressure_n and_o systole_n of_o the_o brain_n and_o succeed_a spirit_n send_v yet_o more_o plentiful_o into_o the_o nervous_a channel_n lead_v to_o the_o muscle_n to_o be_v contract_v than_o into_o those_o which_o be_v in_o motu_fw-la tonico_n or_o into_o the_o antagonist_n the_o passage_n and_o pore_n lead_v to_o those_o nerve_n be_v yet_o more_o expanded_a and_o open_v there_o be_v a_o great_a quantity_n of_o the_o subtle_a liquor_n prepare_v in_o the_o glandule_n and_o thrust_v out_o into_o the_o carnous_a fiber_n and_o their_o cell_n be_v more_o swell_v and_o dilate_a consequent_o there_o follow_v strong_a and_o more_o violent_a contraction_n of_o the_o muscle_n whence_o proceed_v local_a motion_n by_o the_o systole_n of_o the_o brain_n i_o do_v mean_v any_o other_o motion_n than_o what_o proceed_v from_o the_o pulsation_n of_o the_o artery_n distribute_v through_o that_o part._n that_o this_o motion_n only_o proceed_v from_o the_o pulsation_n of_o the_o artery_n imply_v that_o it_o be_v strong_a &_o drive_v the_o spirit_n through_o the_o brain_n into_o the_o nerve_n with_o great_a force_n than_o if_o it_o be_v real_o the_o motion_n of_o the_o brain_n itself_o the_o heart_n from_o whence_o the_o pulsation_n of_o the_o artery_n proceed_v be_v a_o strong_a and_o more_o compact_a part_n as_o to_o its_o substance_n than_o the_o brain_n if_o it_o be_v ask_v why_o this_o subtle_a liquor_n be_v not_o more_o easy_o force_v into_o the_o venous_a duct_n than_o into_o those_o that_o lead_v to_o the_o fibrous_a cell_n because_o the_o former_a be_v large_a i_o answer_v that_o the_o venous_a duct_n be_v so_o proportion_v that_o they_o may_v not_o be_v capable_a of_o receive_v all_o that_o be_v lay_v down_o by_o the_o nerve_n and_o artery_n on_o purpose_n that_o some_o subtle_a part_n may_v be_v continual_o drive_v into_o the_o fibrous_a cell_n and_o when_o by_o a_o more_o copious_a influx_n of_o animal_n spirit_n a_o strong_a fermention_n be_v raise_v in_o the_o glandule_n present_o the_o content_n swell_v up_o and_o be_v expanded_a so_o that_o the_o vein_n be_v not_o able_a to_o receive_v they_o as_o before_o more_o of_o that_o liquor_n be_v not_o only_o subtilise_v but_o force_v into_o the_o fiber_n as_o soon_o as_o according_a to_o our_o appetite_n the_o pore_n of_o the_o brain_n which_o convey_v spirit_n to_o the_o nerve_n lead_v to_o the_o contract_a muscle_n be_v shut_v more_o close_o up_o again_o and_o leave_v of_o to_o be_v dilate_v the_o animal_n spirit_n cease_v to_o flow_v more_o into_o the_o musculous_a glandule_n than_o be_v require_v to_o subtilise_v and_o prepare_v a_o sufficient_a quantity_n of_o nourishment_n for_o the_o fiber_n as_o in_o the_o antagonist_n then_o present_o the_o contraction_n cease_v to_o be_v carry_v on_o and_o the_o superfluous_a liquor_n heap_v up_o in_o the_o fiber_n be_v evacuate_v by_o the_o lymphduct_n here_o perhaps_o because_o i_o say_v in_o the_o forego_n paragraph_n answer_v the_o liquor_n heap_v up_o in_o the_o fiber_n be_v evacuate_v by_o the_o lymphduct_n it_o may_v be_v a_o question_n whether_o this_o liquor_n do_v all_o the_o time_n a_o muscle_n be_v contract_v constant_o flow_v through_o these_o cell_n into_o the_o lymphduct_n or_o whether_o it_o remain_v in_o the_o cell_n till_o motion_n be_v to_o cease_v and_o be_v not_o evacuate_v by_o the_o say_a duct_n till_o then_o i_o say_v it_o do_v continual_o run_v of_o by_o the_o lymphduct_n constant_o all_o the_o time_n a_o muscle_n be_v contract_v otherwise_o since_o as_o long_o as_o spirit_n be_v direct_v in_o a_o competent_a quantity_n to_o the_o contract_a muscle_n to_o keep_v up_o the_o dilation_n of_o the_o fiber_n they_o will_v present_o be_v incapable_a of_o receive_v it_o and_o it_o must_v needs_o regurgitate_v as_o it_o be_v prepare_v and_o in_o a_o great_a measure_n disturb_v circulation_n but_o to_o prevent_v many_o absurd_a consequence_n if_o it_o shall_v remain_v in_o the_o cell_n so_o long_o i_o affirm_v that_o it_o be_v constant_o force_v forward_o by_o a_o succession_n of_o matter_n and_o as_o it_o be_v force_v into_o
to_o get_v it_o forward_o mr._n cowper_n mention_n a_o experiment_n three_o how_o by_o a_o injection_n of_o water_n into_o the_o crural_a artery_n the_o muscle_n of_o the_o leg_n renew_v their_o contraction_n from_o this_o he_o will_v infer_v that_o muscular_a motion_n be_v perform_v by_o the_o blood_n as_o a_o pondus_fw-la but_o though_o his_o myotomia_n argue_v it_o come_v from_o a_o inquisitive_a author_n yet_o i_o rather_o an_o full_o persuade_v that_o the_o blood_n do_v not_o act_n as_o a_o pondus_fw-la because_o this_o experiment_n plead_v against_o it_o but_o to_o avoid_v a_o long_a dispute_n i_o shall_v only_o give_v the_o reason_n of_o the_o phaenomenon_n before_o the_o injection_n of_o this_o water_n the_o branch_n of_o the_o artery_n be_v full_a of_o blood_n and_o arterial_a juice_n and_o when_o by_o the_o mixture_n of_o the_o water_n with_o this_o juice_n it_o be_v attenuate_v and_o drive_v into_o the_o gland_n fast_a than_o it_o can_v be_v receive_v by_o the_o venous_a channel_n the_o most_o subtle_a part_n be_v by_o the_o force_n of_o injection_n strain_v into_o the_o fiber_n and_o distend_v they_o so_o as_o to_o contract_v the_o muscle_n perhaps_o here_o it_o will_v be_v object_v that_o if_o the_o water_n can_v thus_o pass_v through_o into_o the_o fiber_n what_o need_n be_v there_o that_o the_o nerve_n shall_v lay_v down_o their_o content_n in_o the_o glandule_n i_o answer_v that_o the_o water_n be_v thin_a and_o apt_a to_o pass_v through_o those_o duct_n than_o the_o arterial_a juice_n which_o be_v thick_a and_o viscid_a wherefore_o it_o be_v necessary_a that_o the_o nerve_n shall_v lay_v down_o their_o content_n there_o to_o attenuate_v and_o rarisie_n this_o thick_a juice_n i_o have_v see_v people_n incline_v to_o a_o dropsy_n four_o who_o blood_n and_o serum_n be_v much_o dilute_v can_v move_v much_o more_o nimble_o though_o more_o seeble_o than_o some_o of_o a_o healthful_a constitution_n who_o blood_n and_o this_o arterial_a juice_n be_v thick_a and_o not_o so_o much_o dilute_v which_o do_v plain_o show_v that_o the_o thin_a the_o blood_n be_v and_o the_o more_o dilute_v the_o nutritious_a juice_n the_o less_o quantity_n of_o spirit_n be_v require_v to_o subtilise_v it_o and_o make_v it_o capable_a of_o pass_v into_o the_o fiber_n it_o may_v easy_o be_v observe_v that_o those_o people_n who_o spirit_n be_v strong_a five_o and_o their_o arterial_a juice_n very_o thin_a be_v nimble_a but_o the_o contraction_n of_o their_o muscle_n be_v not_o so_o durable_a as_o of_o those_o who_o serum_n be_v of_o a_o thick_a consistence_n for_o though_o in_o the_o former_a more_o of_o the_o subtle_a liquor_n be_v prepare_v yet_o by_o reason_n of_o its_o tenuity_n it_o be_v soon_o receive_v and_o carry_v off_o by_o the_o lymphduct_n which_o make_v the_o contraction_n short_a those_o who_o blood_n abound_v with_o fix_a salt_n &_o phlegmatic_a humour_n six_o which_o too_o much_o dull_a and_o resist_v the_o activity_n of_o the_o animal_n spirit_n be_v always_o slow_a and_o unapt_a for_o motion_n whereas_o if_o the_o blood_n act_v as_o a_o pondus_fw-la they_o must_v be_v more_o nimble_a and_o strong_a because_o the_o thick_a the_o blood_n be_v the_o heavy_a will_v be_v the_o pondus_fw-la as_o muscular_a motion_n be_v many_o way_n vitiate_v by_o the_o fault_n of_o the_o arterial_a juice_n or_o of_o the_o spirit_n and_o consequent_o by_o the_o distemperature_n of_o this_o subtle_a liquor_n so_o it_o be_v very_o often_o deprave_v and_o according_o as_o the_o mass_n of_o blood_n degenerate_v from_o its_o genuine_a and_o proper_a nature_n be_v produce_v various_a disease_n or_o symptom_n of_o disease_n viz._n cramp_n convulsion_n palpitation_n of_o the_o heart_n leap_v of_o the_o tendon_n in_o fever_n etc._n etc._n for_o a_o far_a illustration_n of_o my_o hypothesis_n before_o i_o conclude_v i_o will_v give_v the_o reason_n of_o these_o phonomaena_n when_o by_o a_o abuse_n of_o non-naturals_a the_o ferment_n of_o the_o viscera_n be_v pervert_v convulsion_n and_o by_o the_o fault_n of_o the_o pancreatic_a juice_n and_o of_o the_o spleen_n a_o acid_n or_o austere_a salt_n be_v carry_v forth_o into_o a_o flux_n present_o the_o mass_n of_o blood_n be_v vitiate_a the_o animal_n spirit_n meet_v with_o this_o vicious_a salt_n and_o ferment_v in_o the_o gland_n do_v there_o cause_v irregular_a explosion_n of_o matter_n into_o the_o carnous_a fiber_n subtilise_v in_o that_o fermentation_n whence_o follow_v irregular_a contraction_n of_o the_o muscle_n why_o convulsive_a paroxysm_n come_v at_o uncertain_a time_n will_v easy_o appear_v if_o we_o do_v but_o consider_v the_o procatartick_a cause_n among_o which_o i_o shall_v only_o mention_v two_o viz._n the_o quantity_n of_o morbific_n matter_n irritate_v nature_n to_o a_o expulsion_n of_o it_o and_o sudden_a passion_n of_o the_o mind_n the_o quantity_n of_o morbific_n matter_n be_v far_o great_a in_o some_o body_n than_o in_o other_o before_o the_o spirit_n be_v able_a to_o recover_v themselves_o and_o to_o endeavour_v a_o expulsion_n of_o it_o in_o the_o former_a case_n convulsion_n be_v universal_a and_o seize_v the_o whole_a body_n in_o the_o latter_a particular_a the_o morbific_n matter_n be_v accidental_o drive_v more_o on_o one_o part_n than_o another_o again_o in_o some_o body_n it_o be_v soon_o heap_v up_o be_v generate_v in_o great_a quantity_n the_o matter_n heap_v up_o at_o the_o first_o be_v very_o crude_a and_o thick_a and_o although_o it_o be_v cast_v forth_o into_o and_o circulate_v through_o the_o musculous_a part_n and_o continual_o ferment_n with_o the_o spirit_n in_o the_o glandule_n yet_o because_o it_o be_v not_o sufficient_o attenuate_v to_o be_v drive_v forth_o into_o the_o fleshy_a fiber_n till_o by_o frequent_a circulation_n and_o fermentation_n it_o be_v exalt_v from_o its_o state_n of_o sixedness_n to_o a_o more_o volatile_a no_o convulsion_n succeed_v moreover_o as_o long_o as_o it_o continue_v in_o its_o state_n of_o crudity_n the_o animal_n spirit_n be_v much_o dull_v and_o their_o activity_n quash_v by_o mix_v with_o it_o but_o it_o be_v at_o the_o length_n subtilise_v and_o rarify_v by_o frequent_a circulation_n the_o animal_n spirit_n recover_v they_o self_n and_o violent_o ferment_v with_o it_o in_o the_o gland_n carry_v this_o vicious_a juice_n explosive_o into_o the_o fiber_n the_o reason_n why_o this_o motion_n be_v involuntary_a be_v be_v cause_n it_o be_v not_o produce_v by_o a_o great_a quantity_n of_o spirit_n flow_v from_o the_o brain_n according_o as_o the_o pore_n be_v dilate_v by_o our_o appetite_n but_o by_o a_o mixture_n of_o morbific_a and_o fermentitious_a particle_n which_o cause_n preternatural_a fermentation_n &_o expulsion_n of_o matter_n attenuate_v thereby_o convulsive_a sit_v be_v sometime_o bring_v on_o before_o the_o morbific_a matter_n gradual_o arrive_v at_o this_o state_n of_o tenuity_n when_o upon_o sudden_a passion_n of_o the_o mind_n the_o animal_n faculty_n quit_v their_o station_n and_o be_v overpower_a by_o external_a object_n can_v no_o long_o moderate_v the_o emanation_n of_o the_o animal_n spirit_n the_o formal_a cause_n of_o the_o irregular_a emanation_n of_o the_o spirit_n in_o these_o convulsion_n be_v this_o the_o pore_n of_o the_o brain_n be_v shut_v up_o to_o keep_v out_o external_a object_n heap_v up_o the_o spirit_n till_o by_o reason_n of_o their_o quantity_n the_o pore_n can_v no_o long_o retain_v they_o and_o then_o the_o spirit_n rush_v out_o quà _fw-la datur_fw-la portà _fw-la in_o a_o great_a quantity_n and_o violent_o set_v upon_o the_o crude_a juice_n which_o they_o meet_v with_o in_o the_o glandule_n strong_o ferment_n attenuate_v and_o carry_v it_o forth_o into_o the_o fiber_n of_o the_o muscle_n wherein_o the_o spirit_n be_v thus_o accidental_o lay_v down_o the_o brain_n be_v thus_o empty_v the_o pore_n be_v shut_v up_o again_o till_o the_o quantity_n of_o spirit_n make_v way_n again_o and_o so_o successive_o follow_v convulsive_a motion_n in_o this_o or_o that_o part_n wherever_o the_o spirit_n set_v upon_o the_o crude_a morbific_n matter_n the_o 〈◊〉_d of_o the_o heart_n as_o the_o 〈◊〉_d ed_z dr._n 〈◊〉_d have_v note_v 〈◊〉_d proceed_v 〈◊〉_d convulsive_a motion_n the_o reason_n why_o the_o morbific_a matter_n only_o show_v itself_o in_o this_o part_n and_o at_o the_o same_o time_n in_o no_o other_o part_n of_o the_o body_n in_o this_o the_o mass_n of_o blood_n 〈◊〉_d nate_v with_o a_o morbific_a 〈◊〉_d and_o whatever_o be_v the_o nature_n of_o it_o since_o it_o be_v 〈◊〉_d 〈◊〉_d the_o whole_a body_n 〈◊〉_d 〈◊〉_d rational_o expect_v universal_a convulsion_n as_o well_o as_o 〈◊〉_d but_o this_o morbific_a matter_n be_v as_o yet_o crude_a and_o not_o of_o a_o sufficient_a quantity_n 〈◊〉_d 〈◊〉_d nature_n in_o all_o the_o part_n of_o the_o body_n these_o effect_n be_v only_o produce_v in_o this_o part_n where_o a_o large_a quantity_n of_o spirit_n be_v
continual_o lay_v down_o to_o serment_n with_o it_o by_o which_o mean_v it_o be_v subdue_v in_o this_o part_n before_o it_o arrive_v at_o such_o a_o state_n of_o activity_n of_o such_o a_o quantity_n as_o to_o cause_v irregular_a fermentation_n and_o contraction_n in_o other_o part_n in_o a_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d the_o muscle_n continue_v constant_o contract_v against_o our_o appetite_n 〈◊〉_d these_o distemper_n seize_v people_n who_o blood_n be_v rather_o of_o a_o vitriolic_a tenacious_a nature_n and_o impregnate_v with_o more_o fermentative_a spirit_n so_o that_o by_o reason_n of_o the_o viscidity_n of_o the_o matter_n violent_o force_v into_o the_o fiber_n either_o the_o lymphduct_n be_v obstruct_v or_o by_o reason_n of_o a_o continual_a fermentation_n matter_n gradual_o succeed_v in_o the_o cramp_n the_o fermentation_n be_v different_a from_o that_o which_o be_v natural_a cramp_n or_o in_o other_o convulsive_a motion_n that_o which_o be_v natural_a be_v cause_v by_o the_o animal_n spirit_n prepare_v a_o subtle_a and_o homogenous_a liquor_n in_o other_o convulsion_n the_o animal_n spirit_n ferment_n with_o and_o endeavour_v to_o subdue_v a_o morbific_n humour_n bring_v and_o lay_v down_o by_o the_o artery_n and_o the_o matter_n thus_o attenuate_v be_v accidental_o force_v into_o the_o fiber_n but_o these_o be_v cause_v by_o the_o continual_a conflict_n of_o the_o volatile_a animal_n spirit_n strong_o ferment_v with_o fermentative_a and_o elastic_a particle_n of_o another_o nature_n supply_v by_o the_o mass_n of_o blood_n where_o both_o strive_v to_o subdue_v each_o other_o the_o elastic_a particle_n of_o the_o blood_n more_o strong_o oppose_v the_o motion_n of_o the_o spirit_n and_o the_o spirit_n they_o by_o a_o contrary_a agitation_n and_o intestine_a motion_n of_o their_o particle_n and_o these_o two_o be_v violent_o explode_v and_o impetuous_o leap_v into_o and_o ferment_v in_o the_o fiber_n cause_n most_o strong_a and_o painful_a contraction_n the_o subsultus_fw-la tendinum_fw-la in_o fever_n be_v cause_v fever_n when_o the_o spirit_n be_v too_o much_o exalt_v leap_v irregular_o out_o of_o the_o brain_n and_o raise_v the_o fermentation_n in_o the_o gland_n so_o high_a as_o to_o prepare_v and_o carry_v too_o much_o of_o the_o subtle_a liquor_n into_o the_o fiber_n which_o because_o it_o be_v so_o very_o thin_a easy_o slip_v into_o the_o lymphduct_n and_o make_v the_o contraction_n short_a i_o shall_v add_v the_o reason_n only_o of_o one_o other_o phaenomenon_n cynicus_n which_o seem_v more_o evident_o to_o prove_v that_o muscular_a motion_n depend_v on_o the_o great_a influx_n of_o animal_n spirit_n viz._n why_o the_o contraction_n of_o one_o muscle_n follow_v when_o the_o antagonist_n become_v paralytic_a as_o in_o spasmus_fw-la cynicus_n the_o branch_n of_o the_o nerve_n be_v derive_v from_o the_o brain_n when_o the_o influx_n of_o the_o spirit_n into_o the_o muscle_n of_o the_o one_o side_n be_v hinder_v they_o regurgitate_v and_o be_v drive_v present_o in_o a_o great_a quantity_n into_o the_o antagonist_n as_o by_o the_o loss_n of_o one_o eye_n the_o other_o by_o a_o great_a influx_n of_o spirit_n become_v more_o acute_a this_o be_v evident_a and_o needs_o no_o further_a proof_n thus_o i_o have_v lay_v down_o my_o hypothesis_n of_o the_o formal_a and_o efficient_a cause_n of_o muscular_a motion_n and_o how_o it_o be_v vitiate_a or_o deprave_a which_o i_o the_o more_o willing_o commit_v to_o the_o judgement_n of_o learned_a and_o competent_a judge_n with_o due_a submission_n because_o it_o seem_v to_o i_o to_o answer_v natural_a end_n and_o to_o account_v for_o the_o several_a phaenomena_n without_o the_o difficulty_n enormous_a motion_n and_o impossibility_n which_o usual_o attend_v hypothesis_n on_o this_o subject_a not_o doubt_v but_o it_o will_v give_v satisfaction_n till_o one_o more_o probable_a and_o plausible_a shall_v succeed_v finis_fw-la book_n late_o print_v for_o and_o sell_v by_o a._n &_o j._n churchill_n at_o the_o black_a swan_n in_o pater-noster-row_n a_o view_n of_o universal_a history_n from_o the_o creation_n to_o the_o year_n of_o christ_n 1695._o wherein_o the_o most_o memorable_a person_n and_o thing_n in_o the_o know_a kingdom_n and_o country_n of_o the_o world_n be_v set_v down_o in_o several_a column_n by_o way_n of_o synchronism_n according_a to_o their_o proper_a century_n and_o year_n by_o francis_n talent_n sometime_o fellow_n of_o magdalen-colledge_n cambridge_n the_o whole_a grave_v in_o 16_o copper-plate_n each_o 15_o inch_n deep_a and_o 22_o broad_a bind_v up_o into_o book_n the_o sheet_n line_v a_o work_n of_o great_a exactness_n and_o curiosity_n price_n 16_o s._n a_o complete_a journal_n of_o the_o vote_n speech_n and_o debate_n both_o of_o the_o house_n of_o lord_n and_o house_n of_o commons_o throughout_o the_o whole_a reign_n of_o queen_n elizabeth_n collect_v by_o sir_n simonds_n dewes_n baronet_n and_o publish_v by_o paul_n bowes_n of_o the_o middle-temple_n esq_n the_o second_o edition_n fol._n the_o work_n of_o the_o famous_a nicholas_n machiavelli_n citizen_n and_o secretary_n of_o florence_n written_a original_o in_o italian_a and_o from_o thence_o faithful_o translate_v into_o english_a fol._n mr._n lock_n be_v essay_n concern_v humane_a understanding_n the_o three_o edition_n with_o large_a addition_n fol._n his_o thought_n of_o education_n octavo_fw-la the_o fable_n of_o aesop_n and_o other_o mithologist_n make_v english_a by_o sir_n roger_n l'estrange_n kt._n fol._n two_o treatise_n of_o government_n the_o first_o a_o answer_n to_o filmer_n patriarch_n the_o latter_a a_o essay_n concern_v the_o true_a original_a extent_n &_o end_n of_o civil_a government_n oct._n notitia_fw-la monastica_fw-la or_o a_o short_a history_n of_o the_o religious_a house_n in_o england_n and_o wales_n etc._n etc._n by_o thomas_n tanner_n a._n b._n octavo_fw-la the_o resurrection_n of_o the_o same_z body_n assert_v from_o the_o tradition_n of_o the_o heathen_n the_o ancient_a jew_n and_o the_o primitive_a church_n with_o a_o answer_n to_o the_o objection_n bring_v against_o by_o humphrey_n hody_n d._n d._n bishop_n wilkins_n of_o prayer_n and_o preach_v enlarge_v by_o the_o bishop_n of_o norwich_n and_o dr._n williams_n octavo_fw-la sir_n william_n temple_n '_o be_v history_n of_o the_o netherlands_o octavo_fw-la miscellanea_fw-la octavo_fw-la dr._n patrick_n new_a version_n of_o all_o the_o psalm_n of_o david_n in_o metre_n twelve_o two_o treatise_n of_o natural_a religion_n octavo_fw-la gentleman_n religion_n with_o the_o ground_n and_o reason_n of_o it_o in_o which_o the_o truth_n of_o christianity_n in_o general_n be_v vindicate_v its_o simplicity_n assert_v and_o some_o introductory_n rule_v for_o the_o discover_n of_o its_o particular_a doctrine_n &_o precept_n be_v propose_v by_o a_o private_a gentleman_n sermon_n preach_v by_o dr._n r._n leighâ—on_n late_a a._n bp_o of_o glasgow_n publish_v at_o the_o desire_n of_o his_o friend_n after_o his_o death_n 〈◊〉_d his_o paper_n write_v with_o his_o own_o hand_n the_o second_o edition_n 〈◊〉_d the_o end_n the_o usefulness_n of_o muscular_a motion_n as_o it_o tend_v to_o the_o maintenance_n of_o life_n with_o respect_n to_o the_o soul_n and_o its_o function_n a_o muscle_n be_v a_o noble_a part_n dr._n willis_n opinion_n examine_v no_o elastic_a spirit_n lay_v up_o in_o the_o tendon_n nor_o instinct_n send_v from_o the_o brain_n because_o either_o it_o imply_v that_o the_o spirit_n be_v intelligent_a or_o that_o spirit_n of_o a_o different_a nature_n be_v send_v from_o it_o the_o matter_n be_v not_o intelligent_a no_o spirit_n of_o a_o different_a nature_n be_v send_v from_o the_o brain_n no_o active_a principle_n heap_v up_o in_o the_o fleshy_a fiber_n nor_o retrocession_n of_o subtle_a matter_n into_o the_o tendon_n mr._n cowper_n opinion_n examine_v the_o blood_n do_v not_o act_n as_o a_o pondus_fw-la the_o first_o argument_n a_o second_o a_o three_o a_o five_o a_o six_o dr._n ridley_n opinion_n examine_v the_o common_a postulatum_fw-la be_v not_o to_o be_v allow_v there_o be_v no_o retrocession_n of_o a_o fluid_a from_o the_o autagonist_n nor_o be_v it_o force_v out_o so_o as_o to_o cause_v a_o vacuum_n of_o the_o structure_n of_o a_o muscle_n the_o formal_a cause_n of_o the_o contraction_n of_o a_o muscle_n vessel_n implant_v into_o a_o muscle_n their_o distribution_n and_o termination_n in_o small_a gland_n prove_v what_o a_o gland_n be_v why_o they_o can_v be_v discern_v the_o use_n of_o the_o nerve_n and_o artery_n insert_v in_o the_o gland_n to_o prepare_v a_o liquor_n different_a from_o the_o spirit_n or_o succus_fw-la the_o use_n of_o it_o the_o reason_n of_o tonick_n motion_n objection_n answer_v the_o use_n of_o the_o lymphduct_n the_o nature_n of_o the_o liquor_n consider_v and_o the_o manner_n of_o its_o preparation_n by_o fermentation_n prove_v the_o arterial_a juice_n simple_o can_v cause_v the_o contraction_n of_o a_o muscle_n nor_o the_o animal_n spirit_n because_o the_o arterial_a juice_n can_v pass_v into_o the_o fiber_n till_o prepare_v by_o the_o spirit_n the_o reason_n of_o involuntary_a motion_n prove_v how_o it_o come_v to_o pass_v that_o the_o systole_n of_o the_o heart_n be_v interrupt_v with_o such_o frequent_a diastole_n why_o the_o muscle_n serve_v to_o respiration_n be_v subject_a in_o some_o measure_n to_o our_o appetite_n why_o old_a people_n be_v subject_a to_o a_o tremble_a of_o their_o head_n or_o hand_n another_o phaenomena_n explain_v a_o three_o a_o four_o a_o five_o a_o six_o the_o reason_n of_o convulsion_n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d of_o the_o cramp_n of_o the_o subsultus_fw-la tendinum_fw-la in_o fever_n of_o a_o spasmus_fw-la cynicus_n
and_o circulate_v through_o these_o cell_n in_o great_a or_o less_o quantity_n so_o contraction_n be_v strong_a or_o weak_a or_o not_o at_o all_o the_o fibrous_a cell_n be_v according_o distend_v dilate_v and_o contract_v in_o longitude_n and_o when_o according_a to_o our_o appetite_n this_o liquor_n cease_v to_o flow_v into_o the_o fiber_n in_o so_o great_a a_o quantity_n as_o to_o contract_v the_o muscle_n that_o matter_n which_o before_o dilate_v the_o fiber_n be_v evacuate_v as_o be_v superfluous_a nourishment_n so_o that_o for_o the_o future_a it_o run_v through_o in_o a_o moderate_a quantity_n as_o before_o contraction_n till_o their_o repletion_n be_v again_o renew_a to_o reiterate_v motion_n if_o it_o be_v ask_v why_o this_o liquor_n be_v not_o as_o easy_o force_v backward_o out_o of_o the_o fibrous_a cell_n into_o the_o glandule_n from_o whence_o it_o come_v as_o into_o the_o lymphduct_n and_o so_o think_v there_o will_v be_v no_o need_n for_o lymphduct_n i_o answer_v that_o if_o there_o be_v no_o valve_n at_o the_o inward_a orifice_n of_o every_o dust_n to_o hinder_v its_o reflux_n which_o will_v be_v no_o absurdity_n to_o conclude_v for_o we_o see_v always_o upon_o the_o like_a occasion_n nature_n have_v furnish_v such_o place_n with_o valve_n yet_o i_o say_v if_o there_o be_v none_o the_o direct_a motion_n of_o subsequent_a matter_n from_o the_o glandule_n will_v sufficient_o hinder_v the_o reflux_n of_o it_o and_o since_o its_o reflux_n be_v oppose_v by_o new_a matter_n force_v successive_o after_o it_o and_o since_o according_a to_o the_o course_n of_o circulation_n the_o matter_n drive_v into_o the_o lymphduct_n before_o it_o will_v give_v way_n for_o its_o expulsion_n it_o will_v be_v more_o reasonable_a to_o imagine_v that_o the_o matter_n contain_v in_o the_o fiber_n be_v evacuate_v qua_fw-la datur_fw-la porta_fw-la rather_o than_o qua_fw-la non_fw-la datur_fw-la for_o when_o we_o design_v the_o relaxation_n of_o a_o muscle_n though_o the_o liquor_n successive_o send_v from_o the_o gland_n do_v not_o press_v forward_o altogether_o as_o forcible_o and_o in_o as_o great_a quantity_n as_o whilst_o contraction_n be_v continue_v yet_o it_o follow_v moderate_o so_o as_o to_o oppose_v the_o retrocession_n of_o any_o thing_n i_o mean_v moderate_o as_o to_o its_o quantity_n for_o the_o continual_a violent_a concourse_n of_o the_o animal_n spirit_n and_o arterial_a blood_n drive_v it_o then_o into_o the_o fiber_n almost_o as_o violent_o as_o when_o the_o muscle_n be_v contract_v that_o these_o lymphduct_n do_v thus_o receive_v this_o subtle_a liquor_n lymphduct_n and_o that_o for_o that_o end_n they_o be_v insert_v into_o the_o fibrous_a cell_n i_o be_o persuade_v because_o it_o can_v otherwise_o be_v understand_v how_o the_o matter_n that_o stuff_v they_o up_o and_o cause_n contraction_n can_v be_v draw_v out_o again_o without_o a_o retrocession_n through_o the_o same_o channel_n by_o which_o it_o be_v bring_v in_o and_o though_o the_o most_o learned_a and_o famous_a dr._n willis_n dr._n ridley_n and_o other_o do_v allow_v a_o retrocession_n yet_o since_o it_o contradict_v the_o course_n of_o circulation_n we_o must_v either_o deny_v circulation_n or_o reject_v their_o opinion_n beside_o i_o can_v conceive_v what_o other_o occasion_n there_o be_v for_o lymphduct_n in_o a_o muscle_n since_o whatever_o be_v bring_v by_o the_o artery_n may_v as_o well_o be_v return_v by_o the_o vein_n as_o by_o two_o sort_n of_o vessel_n but_o for_o as_o much_o as_o nature_n have_v make_v nothing_o in_o vain_a and_o since_o there_o be_v so_o great_a necessity_n that_o they_o shall_v be_v insert_v into_o the_o cell_n i_o think_v it_o not_o irrational_a nor_o absurd_a to_o conclude_v they_o be_v design_v for_o the_o aforementioned_a end_n that_o we_o may_v understand_v a_o little_a better_o the_o nature_n of_o this_o liquor_n preparation_n which_o we_o have_v so_o often_o mention_v let_v we_o consider_v a_o little_a more_o full_o how_o that_o fermentation_n be_v carry_v on_o in_o the_o say_a glandule_n it_o be_v common_o know_v that_o when_o a_o ferment_n be_v put_v to_o a_o mass_n whether_o liquid_a or_o of_o a_o solid_a consistence_n whatever_o be_v the_o nature_n of_o the_o ferment_n it_o according_a to_o its_o power_n always_o endeavour_v to_o render_v whatever_o come_v within_o the_o sphere_n of_o its_o activity_n as_o like_o it_o as_o possible_a fermentation_n so_o in_o these_o glandule_n the_o animal_n spirit_n ferment_v with_o the_o arterial_a juice_n and_o the_o nature_n of_o they_o be_v according_a to_o dr._n willis_n and_o diemerbroeck_n spirituo-saline_n compose_v of_o volitile_o salt_n and_o sulphur_n they_o by_o reason_n of_o their_o absolute_a quality_n more_o ready_o mix_v with_o the_o crude_a sulphureo-saline_a particle_n of_o the_o nutricious_a arterial_a juice_n and_o as_o they_o be_v more_o or_o less_o in_o quantity_n so_o they_o exalt_v and_o carry_v forth_o into_o a_o flux_n more_o or_o less_o of_o that_o crude_a sulphureo-saline_a mass_n which_o be_v by_o fermentation_n subtilise_v be_v dilute_v with_o a_o sufficient_a quantity_n of_o lympha_fw-la or_o the_o watery_a part_n of_o the_o serum_n of_o the_o blood_n and_o the_o liquor_n result_v from_o that_o composition_n be_v thrust_v out_o into_o the_o fibrous_a cell_n that_o this_o lympha_fw-la might_n be_v thin_a enough_o to_o dilute_v the_o say_a liquor_n sufficient_o it_o be_v much_o attenuate_v in_o that_o fermentation_n that_o there_o be_v such_o a_o fermentation_n prove_v that_o the_o nerve_n be_v insert_v into_o the_o glandule_n and_o lay_v down_o animal_n spirit_n as_o the_o principal_a cause_n of_o that_o fermentation_n that_o the_o artery_n lay_v down_o blood_n together_o with_o the_o aforementioned_a juice_n and_o that_o in_o those_o gland_n a_o subtle_a liquor_n be_v prepare_v be_v compose_v of_o animal_n spirit_n and_o the_o most_o rarefy_v part_n of_o the_o say_v succus_fw-la that_o neither_o the_o arterial_a juice_n nor_o the_o animal_n spirit_n simple_o can_v cause_v the_o contraction_n of_o a_o muscle_n but_o furthermore_o that_o it_o be_v necessary_a that_o this_o subtle_a liquor_n shall_v be_v so_o prepare_v and_o compose_v as_o be_v capable_a to_o enter_v into_o the_o fiber_n and_o to_o contract_v the_o muscle_n be_v sufficient_o apparent_a from_o what_o have_v be_v say_v and_o will_v more_o clear_o be_v evince_v by_o what_o follow_v and_o first_o if_o there_o be_v a_o communication_n of_o these_o vessel_n as_o certain_o there_o be_v than_o it_o must_v needs_o follow_v that_o there_o be_v a_o commixture_n of_o their_o content_n if_o there_o be_v a_o commixture_n of_o their_o content_n than_o there_o be_v a_o fermentation_n and_o in_o that_o fermentation_n it_o must_v needs_o follow_v that_o the_o animal_n spirit_n will_v according_a to_o their_o energy_n and_o activity_n subtilise_v and_o attenuate_v the_o crude_a part_n of_o the_o arterial_a juice_n by_o a_o mutual_a fermentation_n there_o must_v needs_o be_v employ_v a_o intimate_a commixture_n and_o the_o result_n of_o that_o commixture_n must_v needs_o be_v different_a from_o the_o animal_n spirit_n or_o arterial_a juice_n simple_o before_o they_o be_v mix_v so_o that_o the_o liquor_n result_v from_o the_o mixture_n of_o they_o may_v be_v proper_o call_v a_o subtle_a liquor_n and_o according_o as_o the_o animal_n spirit_n be_v more_o or_o less_o in_o quantity_n to_o mix_v with_o the_o arterial_a juice_n more_o or_o less_o will_v be_v prepare_v and_o thrust_v out_o into_o the_o fibrous_a cell_n and_o consequent_o the_o fibrous_a cell_n must_v be_v more_o or_o less_o tumify_v and_o the_o muscle_n contract_v as_o more_o or_o less_o spirit_n be_v lay_v down_o in_o the_o glandule_n so_o that_o all_o i_o have_v to_o prove_v be_v that_o neither_o the_o arterial_a juice_n nor_o the_o animal_n spirit_n can_v cause_v the_o contraction_n of_o a_o muscle_n and_o then_o it_o will_v follow_v consequent_o that_o there_o be_v a_o communication_n of_o these_o vessel_n and_o for_o that_o end_n in_o the_o aforesaid_a glandule_n it_o have_v often_o be_v find_v that_o a_o atrophea_fw-la of_o the_o part_n will_v follow_v the_o relaxation_n muscle_n &_o a_o palsy_n the_o abscission_n or_o ligature_n of_o the_o nerve_n lead_v to_o those_o part_n which_o sufficient_o show_v that_o the_o arterial_a juice_n itself_o can_v cause_v the_o contraction_n of_o a_o muscle_n without_o the_o assistance_n of_o the_o animal_n spirit_n because_o when_o the_o animal_n spirit_n cease_v to_o flow_v into_o the_o glandule_n for_o want_v of_o a_o due_a fermentation_n to_o subtilise_v and_o prepare_v a_o sufficient_a quantity_n of_o the_o arterial_a juice_n the_o carnous_a fiber_n be_v not_o only_o deprive_v of_o necessary_a recruit_n and_o alimental_a refreshment_n so_o that_o they_o must_v needs_o waste_v away_o and_o grow_v languid_a but_o also_o for_o want_v of_o a_o sufficient_a quantity_n of_o the_o subtle_a liquor_n to_o distend_v the_o fibrous_a cell_n
they_o become_v destitute_a of_o motion_n that_o the_o animal_n spirit_n simple_o spirit_n can_v cause_v the_o contraction_n of_o a_o muscle_n be_v prove_v because_o by_o a_o ligature_n on_o the_o descend_v trunk_n of_o the_o aorta_fw-mi the_o inferior_a part_n become_v destitute_a of_o motion_n for_o though_o the_o influx_n of_o the_o animal_n spirit_n be_v not_o hinder_v yet_o for_o want_v of_o arterial_a juice_n the_o matter_n requisite_a for_o the_o composition_n of_o this_o subtle_a liquor_n be_v not_o lay_v down_o in_o the_o glandule_n and_o the_o muscle_n the_o instrument_n of_o motion_n can_v contract_v without_o a_o efficient_a cause_n from_o what_o be_v contain_v in_o these_o two_o paragraph_n it_o appear_v that_o neither_o the_o animal_n spirit_n nor_o the_o arterial_a juice_n simple_o can_v cause_v the_o contraction_n of_o a_o muscle_n because_o when_o the_o animal_n spirit_n be_v hinder_v to_o flow_v into_o the_o glandule_n to_o subtilise_v and_o prepare_v the_o arterial_a juice_n it_o be_v not_o thin_a enough_o to_o be_v drive_v out_o into_o the_o fiber_n and_o though_o when_o the_o influx_n of_o the_o arterial_a juice_n be_v hinder_v the_o spirit_n be_v permit_v to_o flow_v in_o yet_o by_o reason_n of_o the_o small_a quantity_n of_o they_o they_o run_v through_o the_o fiber_n without_o distend_v '_o they_o that_o this_o arterial_a juice_n ought_v not_o spirit_n nay_o can_v pass_v into_o the_o fibrous_a cell_n till_o subtilise_v and_o prepare_v by_o the_o fermentation_n in_o the_o glandule_n be_v plain_a because_o if_o it_o can_v they_o will_v be_v stuff_v up_o with_o the_o quantity_n of_o it_o drive_v in_o by_o the_o continual_a course_n of_o circulation_n so_o as_o to_o contract_v the_o muscle_n against_o our_o will_n which_o be_v otherwise_o now_o since_o the_o arterial_a juice_n can_v pass_v into_o the_o fiber_n till_o subtilise_v and_o since_o the_o animal_n spirit_n be_v not_o enough_o in_o quantity_n moreover_o since_o neither_o of_o they_o simple_o be_v capable_a of_o contract_n the_o fiber_n and_o if_o either_o be_v obstruct_v the_o action_n be_v abolish_v i_o say_v since_o it_o be_v a_o action_n that_o depend_v upon_o the_o mutual_a assistance_n of_o each_o it_o be_v apparent_a that_o it_o must_v be_v perform_v by_o a_o liquor_n result_v from_o a_o mixture_n of_o both_o and_o then_o we_o must_v of_o necessity_n allow_v a_o communication_n of_o these_o vessel_n else_o there_o can_v be_v no_o mixture_n of_o their_o content_n and_o the_o arterial_a juice_n must_v be_v prepare_v before_o it_o can_v be_v force_v into_o the_o fiber_n for_o the_o reason_n beforementioned_a to_o which_o end_n it_o will_v be_v necessary_a that_o the_o vessel_n terminate_v in_o the_o glandule_n that_o their_o content_n may_v be_v mix_v and_o that_o this_o subtle_a liquor_n result_v from_o a_o mutual_a conflict_n of_o the_o animal_n spirit_n subtilize_v the_o cruder_n arterial_a juice_n by_o fermentation_n in_o great_a or_o less_o quantity_n according_o as_o the_o spirit_n be_v lay_v down_o by_o the_o nerve_n may_v be_v prepare_v and_o make_v ready_a to_o be_v drive_v into_o the_o fiber_n to_o promote_v the_o fermentation_n and_o the_o preparation_n of_o this_o subtle_a liquor_n the_o forcible_a influx_n of_o the_o animal_n spirit_n and_o of_o the_o arterial_a blood_n much_o conduce_v for_o be_v the_o temper_n of_o the_o arterial_a juice_n and_o of_o the_o animal_n spirit_n never_o so_o good_a unless_o they_o be_v drive_v violent_o one_o against_o another_o there_o will_v be_v require_v a_o long_a time_n before_o they_o can_v be_v so_o mix_v and_o ferment_v as_o they_o ought_v but_o the_o succession_n of_o new_a matter_n admit_v no_o long_a delay_n it_o be_v requisite_a that_o they_o shall_v be_v thus_o forcible_o drive_v in_o together_o to_o the_o end_n that_o the_o spirit_n may_v be_v diffuse_v through_o the_o whole_a mass_n soon_o and_o that_o their_o minute_n particle_n strike_v more_o violent_o against_o the_o fix_a and_o compact_a particle_n of_o the_o blood_n may_v more_o immediate_o break_v and_o separate_v the_o strict_a union_n of_o its_o part_n and_o by_o a_o violent_a fermentation_n sufficient_o dissolve_v and_o volatilize_v they_o in_o so_o short_a a_o time_n as_o the_o continual_a pulsation_n of_o succeed_a humour_n admit_v the_o violent_a concourse_n of_o the_o blood_n and_o spirit_n do_v not_o only_o promote_v this_o fermentation_n and_o the_o separation_n of_o the_o subtle_a liquor_n but_o also_o successive_o force_v the_o matter_n prepare_v and_o separate_v into_o the_o fleshy_a fiber_n this_o be_v so_o high_o probable_a that_o it_o need_v no_o argument_n to_o make_v it_o more_o evident_a it_o be_v the_o unavoidable_a consequence_n of_o a_o continual_a circulation_n now_o i_o have_v give_v the_o reason_n of_o voluntary_a motion_n and_o the_o efficient_a cause_n of_o the_o contraction_n of_o a_o muscle_n it_o will_v be_v easy_a to_o unfold_v the_o reason_n of_o involuntary_a motion_n that_o voluntary_a motion_n depend_v upon_o the_o will_n be_v manifest_a and_o that_o involuntary_a motion_n be_v not_o at_o all_o subject_a to_o it_o but_o be_v perform_v not_o only_o without_o the_o dictate_v of_o our_o appetite_n but_o against_o they_o be_v so_o evident_a that_o it_o will_v be_v superfluous_a and_o useless_a to_o dispute_v it_o i_o shall_v only_o show_v how_o it_o be_v perform_v which_o be_v indeed_o a_o little_a more_o obscure_a as_o voluntary_a motion_n be_v perform_v motion_n for_o as_o much_o as_o the_o pore_n of_o the_o brain_n be_v dilate_v according_a to_o our_o appetite_n so_o that_o the_o animal_n spirit_n flow_v more_o plentiful_o into_o the_o glandule_n and_o prepare_v a_o sufficient_a quantity_n of_o the_o subtle_a liquor_n to_o distend_a the_o fiber_n as_o it_o pass_v through_o they_o so_o those_o pore_n which_o lead_v to_o the_o nerve_n serve_v to_o involuntary_a motion_n be_v proportion_v in_o such_o a_o manner_n that_o they_o continual_o convey_v animal_n spirit_n in_o a_o sufficient_a quantity_n to_o cause_v a_o perpetual_a motion_n these_o pore_n be_v so_o proportion_v there_o be_v no_o need_n that_o they_o shall_v have_v such_o a_o organic_n motion_n as_o those_o serve_n to_o the_o instrument_n of_o voluntary_a motion_n because_o since_o they_o be_v proportion_v so_o as_o to_o carry_v spirit_n in_o a_o competent_a quantity_n there_o be_v no_o necessity_n that_o they_o shall_v be_v either_o dilate_v or_o contract_v to_o prove_v that_o these_o pore_n do_v lay_v down_o a_o competent_a quantity_n of_o spirit_n to_o be_v carry_v to_o the_o gland_n prove_v i_o need_v not_o bring_v many_o argument_n for_o its_o plain_a and_o evident_a to_o all_o practitioner_n in_o physic_n that_o when_o the_o spirit_n be_v too_o much_o carry_v forth_o and_o exalt_v as_o in_o a_o diary_n fever_n the_o pulse_n be_v strong_a and_o vehement_a and_o by_o a_o too_o great_a exagitation_n of_o they_o it_o become_v more_o quick_a and_o frequent_a it_o be_v also_o evident_a that_o when_o the_o animal_n spirit_n be_v depress_v the_o pulse_n be_v weak_a slow_a and_o rare_a as_o most_o common_o in_o woman_n subject_a to_o hysterick_n fit_v and_o when_o the_o spirit_n by_o a_o acute_a or_o cronick_a distemper_n be_v wear_v out_o and_o almost_o spend_v the_o pulse_n be_v either_o vermiculans_n formicans_fw-la or_o tremens_fw-la which_o be_v sign_n that_o nature_n be_v almost_o spend_v and_o ready_a to_o yield_v to_o the_o distemper_n i_o say_v this_o be_v evident_a enough_o it_o be_v then_o beyond_o contradiction_n that_o a_o healthful_a pulse_n depend_v upon_o a_o moderate_a quantity_n of_o animal_n spirit_n and_o that_o they_o continual_o flow_v into_o those_o nerve_n lead_v to_o the_o instrument_n of_o involuntary_a motion_n and_o as_o their_o quantity_n vary_v so_o more_o or_o less_o of_o the_o subtle_a liquor_n be_v prepare_v to_o distend_a the_o fiber_n of_o those_o muscle_n when_o the_o spirit_n be_v weak_a or_o almost_o spend_v there_o must_v needs_o flow_v a_o less_o quantity_n into_o the_o glandule_n and_o when_o they_o be_v exalt_v a_o great_a and_o if_o extreme_n either_o frustrate_a natural_a or_o cause_n preternatural_a effect_n we_o may_v not_o only_o conclude_v that_o natural_a action_n be_v perform_v by_o a_o moderate_a quantity_n but_o from_o hence_o we_o may_v bring_v good_a argument_n for_o a_o further_a proof_n and_o confirmation_n of_o my_o hypothesis_n about_o voluntary_a motion_n since_o i_o have_v say_v that_o the_o spirit_n diastole_n by_o reason_n of_o a_o particular_a proportion_n of_o the_o pore_n flow_v continual_o in_o a_o just_a quantity_n and_o that_o these_o pore_n be_v not_o subject_a to_o be_v dilate_v or_o contract_v according_a to_o our_o appetite_n it_o remain_v that_o i_o shall_v show_v how_o it_o come_v to_o pass_v that_o the_o systole_n of_o the_o heart_n be_v interrupt_v with_o such_o constant_a diastole_n whereas_o when_o the_o pore_n serve_v to_o voluntary_a contraction_n be_v
a_o treatise_n of_o the_o reason_n of_o muscular_a motion_n or_o the_o efficient_a cause_n of_o the_o contraction_n of_o a_o muscle_n wherein_o most_o of_o the_o phaenomena_n about_o muscular_a motion_n be_v explain_v by_o richard_n boulton_n of_o the_o city_n of_o chester_n medicine_n proficiens_fw-la 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d london_n print_v by_o a._n and_o j._n churchill_n at_o the_o black_a swan_n in_o pater-noster-row_n 1697._o tractatum_fw-la hunc_fw-la cui_fw-la titulus_fw-la a_o treatise_n of_o the_o reason_n of_o muscular_a motion_n etc._n etc._n dignum_fw-la censemus_fw-la quî_fw-la imprimatur_fw-la samuel_n collins_n praeses_fw-la thomas_n burwell_n sen._n richard_n torless_a william_n dawes_n thomas_n gill_n censor_n datum_n in_o comitiis_fw-la censoriis_fw-la ex_fw-la aedibus_fw-la collegii_fw-la nostri_fw-la sept._n 11._o 1696._o to_o the_o most_o learned_a and_o ever_o honour_a dr._n collins_n precedent_n dr._n thomas_n burwell_n dr._n richard_n torlesse_a dr._n william_n dawes_n dr._n thomas_n gill._n censor_n of_o the_o college_n of_o physician_n this_o treatise_n be_v humble_o dedicate_v by_o your_o most_o faithful_a and_o obedient_a servant_n r._n boulton_n to_o the_o reader_n i_o have_v examine_v this_o treatise_n with_o the_o strict_a reason_n that_o i_o be_o master_n of_o and_o it_o appear_v to_o i_o reasonable_a in_o every_o particular_a but_o i_o be_o altogether_o desirous_a of_o truth_n and_o will_v not_o out_o of_o any_o fond_a opinion_n of_o my_o own_o hypothesis_n receive_v it_o soon_o than_o another_o man_n i_o be_o most_o incline_v to_o suspect_v whatever_o be_v a_o faetus_fw-la of_o my_o own_o brain_n if_o it_o may_v be_v any_o way_n serviceable_a to_o other_o i_o have_v my_o desire_n the_o content_n the_o usefulness_n of_o muscular_a motion_n as_o it_o tend_v to_o the_o maintenance_n of_o life_n page_z 1_o with_o respect_n to_o the_o soul_n and_o the_o animal_n function_n p._n 3_o dr._n willis_n opinion_n examine_v p._n 7_o mr._n cowper_n opinion_n examine_v p._n 20_o dr._n ridley_n opinion_n examine_v p._n 30_o the_o structure_n of_o a_o muscle_n p._n 40_o the_o formal_a cause_n of_o the_o contraction_n of_o a_o muscle_n p._n 41_o vessel_n implant_v into_o a_o muscle_n p._n 42_o their_o distribution_n p._n 43_o and_o termination_n in_o small_a glandule_n p._n 45_o what_o a_o gland_n be_v p._n 47_o the_o use_n of_o the_o nerve_n p._n 52_o and_o artery_n insert_v in_o the_o gland_n p._n 53_o to_o prepare_v a_o subtle_a liquor_n ibid._n the_o use_n of_o it_o p._n 54_o the_o reason_n of_o tonick_n motion_n p._n 59_o of_o local_a motion_n p._n 60_o the_o use_n of_o the_o lymphduct_n p._n 68_o the_o nature_n of_o the_o liquor_n and_o the_o manner_n of_o its_o preparation_n p._n 69_o by_o fermentation_n p._n 70_o prove_v p._n 72_o the_o reason_n of_o involuntary_a motion_n p._n 82_o why_o the_o systole_n of_o the_o heart_n be_v interrupt_v with_o frequent_a diastole_n p._n 86_o why_o the_o muscle_n serve_v to_o respiration_n be_v in_o some_o measure_n subject_a to_o our_o appetite_n p._n 90_o some_o phaenomena_n about_o muscular_a motion_n explain_v p._n 93_o the_o reason_n of_o convulsion_n p._n 103_o of_o the_o palpitation_n of_o the_o heart_n p._n 109_o of_o the_o cramp_n p._n 111_o of_o the_o subsultus_fw-la tendinum_fw-la in_o fever_n p._n 113_o of_o spasmus_fw-la lynicus_n p._n 114_o of_o the_o reason_n of_o muscular_a motion_n or_o the_o efficient_a cause_n of_o the_o contraction_n of_o a_o muscle_n etc._n etc._n if_o we_o consider_v the_o usefulness_n of_o muscular_a motion_n life_n with_o respect_n to_o a_o individual_a and_o that_o either_o as_o it_o tend_v to_o the_o maintenance_n of_o life_n or_o the_o perfection_n of_o man_n that_o be_v with_o respect_n to_o the_o soul_n and_o the_o animal_n function_n it_o be_v the_o very_a spring_n upon_o which_o all_o our_o action_n both_o natural_a vital_a and_o animal_n whole_o depend_v by_o the_o assistance_n of_o muscular_a motion_n all_o the_o part_n of_o our_o body_n perform_v their_o particular_a office_n our_o food_n be_v prepare_v by_o mastication_n and_o convey_v to_o the_o stomach_n the_o concoct_v chymus_fw-la be_v thence_o expel_v into_o the_o intestine_n where_o the_o pure_a chyle_n be_v separate_v from_o the_o impure_a faeces_fw-la every_o peculiar_a liquor_n circulate_v through_o its_o distinct_a and_o proper_a vessel_n the_o chyle_n through_o its_o lacteal_v and_o the_o lympha_fw-la through_o its_o duct_n and_o the_o mass_n of_o blood_n be_v disribute_v through_o the_o artery_n that_o all_o the_o part_n of_o the_o body_n both_o principal_a and_o subsubservient_fw-fr noble_a and_o ignoble_a may_v receive_v their_o proper_a liquor_n in_o a_o word_n it_o be_v by_o this_o very_a action_n of_o muscular_a motion_n that_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d if_o we_o respect_v the_o animal_n function_n function_n they_o so_o much_o depend_v upon_o muscular_a motion_n that_o when_o the_o heart_n cease_v to_o move_v all_o the_o faculty_n of_o the_o soul_n be_v present_o extinguish_v the_o faculty_n of_o the_o soul_n be_v not_o only_o dependent_a on_o involuntary_a but_o also_o voluntary_a motion_n without_o which_o both_o our_o eye_n and_o ear_n will_v be_v unfit_a to_o receive_v external_a object_n and_o man_n will_v be_v endow_v with_o a_o sensitive_a and_o rational_a soul_n to_o no_o purpose_n our_o outward_a sense_n will_v in_o vain_a receive_v external_a object_n unless_o we_o have_v a_o intelligent_a faculty_n in_o vain_a shall_v we_o understand_v unless_o we_o have_v reason_n to_o distinguish_v good_a from_o evil_n that_o we_o may_v desire_v the_o one_o and_o contemn_v the_o other_o in_o vain_a also_o will_v be_v the_o dictate_v of_o our_o reason_n if_o we_o have_v not_o a_o loco-motive_n faculty_n to_o pursue_v those_o thing_n we_o desire_v and_o to_o flee_v from_o those_o thing_n which_o we_o be_v willing_a to_o avoid_v but_o by_o muscular_a motion_n the_o dictate_v of_o our_o reason_n according_o as_o they_o be_v bias_v by_o our_o appetite_n be_v put_v into_o action_n and_o the_o intimate_a result_v of_o all_o our_o faculty_n be_v bring_v to_o light_n muscular_a motion_n be_v the_o very_a index_n animi_fw-la by_o which_o the_o temper_n and_o disposition_n of_o the_o animal_n faculty_n be_v make_v evident_a it_o be_v the_o ultimate_a result_n of_o our_o most_o secret_a thought_n and_o of_o our_o will_n so_o that_o if_o we_o weigh_v but_o the_o mutual_a dependence_n of_o all_o the_o part_n of_o a_o man_n body_n part_n there_o be_v no_o reason_n that_o a_o muscle_n shall_v be_v term_v a_o ignoble_a part_n since_o by_o the_o loss_n of_o a_o single_a one_o either_o the_o natural_a vital_a or_o animal_n faculty_n be_v in_o some_o measure_n vitiate_v the_o stomach_n the_o liver_n the_o spleen_n the_o lung_n etc._n etc._n be_v all_o subordinate_a and_o subservient_fw-fr to_o the_o principle_n faculty_n of_o the_o soul_n in_o as_o much_o as_o they_o by_o their_o mutual_a symbolum_n prepare_v the_o pabulum_fw-la of_o the_o animal_n spirit_n but_o the_o muscle_n design_v for_o motion_n especial_o voluntary_a in_o as_o much_o as_o the_o most_o perfect_a and_o refine_a action_n of_o the_o soul_n be_v perform_v and_o express_v by_o muscular_a motion_n be_v of_o a_o more_o noble_a use_n the_o perfection_n of_o man_n consist_v more_o immediate_o on_o the_o energy_n and_o execution_n of_o the_o principal_a faculty_n of_o the_o soul_n than_o in_o the_o subordinate_a and_o subservient_fw-fr faculty_n both_o natural_a and_o vital_a for_o as_o much_o as_o the_o life_n and_o perfection_n of_o man_n so_o much_o depend_v on_o muscular_a motion_n i_o shall_v inquire_v into_o the_o efficient_a cause_n of_o it_o but_o before_o i_o propose_v my_o own_o hypothesis_n it_o be_v necessary_a that_o i_o first_o confute_v what_o have_v hitherto_o be_v say_v on_o this_o subject_n nevertheless_o because_o it_o will_v be_v too_o tedious_a to_o examine_v the_o opinion_n of_o so_o many_o author_n i_o will_v only_o show_v the_o error_n of_o two_o or_o three_o of_o the_o late_a and_o most_o considerable_a the_o most_o learned_a and_o famous_a dr._n willis_n conjecture_n examine_v that_o the_o spirit_n be_v convey_v to_o the_o tendon_n of_o a_o muscle_n and_o be_v there_o plentiful_o lay_v up_o as_o in_o a_o convenient_a storehouse_n which_o spirit_n be_v of_o a_o agile_a and_o elastic_a nature_n as_o far_o as_o they_o be_v able_a and_o be_v permit_v always_o endeavour_v to_o expand_v themselves_o and_o that_o when_o a_o instinct_n to_o perform_v muscular_a motion_n be_v carry_v from_o the_o brain_n or_o cerebell_n to_o this_o common_a storehouse_n they_o present_o leap_v out_o of_o the_o tendinous_a into_o the_o fleshy_a fiber_n where_o they_o meet_v with_o active_a principle_n of_o another_o nature_n supply_v by_o the_o mass_n of_o blood_n which_o two_o strong_o &_o mutual_o ferment_v stuff_v up_o and_o tumifie_v the_o fleshy_a fiber_n whence_o proceed_v the_o
contraction_n of_o a_o muscle_n when_o the_o contraction_n cease_v he_o think_v that_o most_o of_o the_o pure_a spirit_n that_o remain_v return_v into_o the_o tendon_n the_o other_o more_o impure_a particle_n remain_v among_o the_o fleshy_a fiber_n he_o fancy_v that_o the_o fiber_n of_o the_o outward_a membrane_n contract_v promote_v the_o retrocession_n of_o the_o spirit_n into_o the_o tendon_n and_o that_o for_o a_o continual_a supply_n of_o these_o liquor_n the_o one_o be_v always_o store_v up_o in_o the_o tendon_n through_o the_o nerve_n and_o the_o other_o in_o the_o carnous_a fiber_n from_o the_o mass_n of_o blood_n this_o conjecture_n as_o it_o seem_v ingenious_a tendon_n and_o at_o the_o first_o view_n very_o mysterious_a yet_o upon_o a_o more_o strict_a examination_n it_o appear_v altogether_o as_o improbable_a for_o to_o suppose_v that_o these_o elastic_a spirit_n be_v lay_v up_o and_o store_v in_o the_o tendinous_a fiber_n be_v contradictory_n to_o reason_n as_o well_o as_o the_o law_n of_o circulation_n for_o since_o in_o every_o systole_n of_o the_o brain_n a_o fresh_a supply_n of_o animal_n spirit_n be_v send_v into_o all_o the_o branch_n of_o the_o nerve_n those_o animal_n spirit_n in_o the_o tendinous_a fiber_n must_v needs_o by_o a_o succession_n of_o new_a matter_n be_v press_v forward_o into_o the_o fleshy_a fibre_n and_o consequent_o accidental_a contraction_n must_v follow_v for_o as_o much_o as_o there_o be_v no_o valve_n to_o hinder_v their_o immediate_a passage_n and_o that_o there_o be_v no_o valve_n nor_o any_o thing_n else_o to_o stop_v the_o continual_a passage_n of_o these_o spirit_n may_v be_v argue_v hence_o because_o whatever_o will_v stop_v the_o protrusion_n of_o these_o spirit_n when_o press_v by_o the_o systole_n of_o the_o brain_n will_v also_o hinder_v they_o from_o rush_v out_o of_o their_o storehouse_n though_o stir_v up_o by_o a_o instinct_n and_o so_o the_o muscle_n will_v be_v deprive_v of_o motion_n but_o suppose_v that_o it_o be_v possible_a for_o these_o elastic_a spirit_n to_o be_v store_v up_o in_o the_o tendinous_a fiber_n and_o that_o neither_o their_o agility_n and_o continual_a endeavour_n to_o explosion_n nor_o the_o force_n of_o succeed_a spirit_n will_v drive_v they_o out_o yet_o when_o a_o muscle_n cease_v from_o motion_n perhaps_o a_o day_n or_o two_o the_o tendon_n will_v be_v so_o fill_v and_o stuff_v up_o that_o be_v no_o long_o capable_a of_o receive_v more_o spirit_n either_o they_o must_v be_v force_v forth_o into_o the_o carnous_a fiber_n and_o cause_v violent_a and_o involuntary_a contraction_n or_o regurgitate_v and_o flow_v back_o upon_o the_o brain_n will_v there_o cause_v a_o vertigo_n or_o some_o other_o more_o fatal_a disease_n and_o beside_o the_o spirit_n by_o stagnate_v so_o long_o will_v be_v chill_v and_o coagulate_v and_o thereby_o render_v unapt_a for_o motion_n it_o be_v not_o only_o absurd_a to_o imagine_v because_o that_o the_o tendon_n be_v storehouse_n for_o spirit_n but_o also_o that_o they_o the_o instinct_n be_v give_v shall_v cush_o out_n of_o the_o carnous_a fiber_n one_o may_v as_o well_o think_v that_o the_o content_n of_o the_o stomach_n the_o gall_n in_o the_o vesica_fw-la bilaria_n or_o the_o urine_n in_o the_o bladder_n may_v be_v exclude_v by_o instinct_n mere_o without_o the_o help_n of_o muscular_a coat_n or_o that_o the_o circulation_n of_o the_o blood_n may_v be_v carry_v on_o without_o the_o systole_n and_o diastole_n of_o the_o heart_n moreover_o intelligent_a to_o allow_v that_o those_o elastic_a spirit_n do_v after_o this_o manner_n rush_v into_o the_o carnous_a fiber_n when_o the_o instinct_n be_v give_v from_o the_o brain_n or_o to_o speak_v more_o proper_o ad_fw-la imperium_fw-la animae_fw-la either_o imply_v that_o those_o spirit_n which_o dr._n willis_n call_v materiam_fw-la subtilem_fw-la be_v intelligent_a matter_n that_o they_o be_v able_a to_o understand_v the_o dictate_v and_o command_v of_o the_o soul_n and_o to_o put_v they_o in_o execution_n proprio_fw-la motu_fw-la or_o that_o some_o spirit_n of_o a_o different_a nature_n it_o be_v at_o the_o command_n of_o the_o soul_n send_v from_o the_o brain_n which_o cause_n the_o spirit_n in_o the_o tendon_n to_o be_v uneasy_a and_o by_o exagitation_n to_o expand_v themselves_o more_o powerful_o and_o consequent_o to_o leap_v forth_o but_o if_o neither_o the_o texture_n of_o those_o spirit_n which_o as_o dr._n willis_n say_v give_v the_o instinct_n be_v change_v and_o different_a from_o those_o in_o the_o tendon_n nor_o the_o subtle_a matter_n be_v intelligent_a there_o will_v be_v no_o explosion_n or_o leap_v forth_o of_o the_o spirit_n out_o of_o the_o tendon_n either_o by_o instinct_n or_o the_o accession_n of_o new_a matter_n from_o the_o nerve_n except_o as_o i_o note_v before_o the_o spirit_n which_o fill_v the_o tendinous_a fiber_n be_v drive_v and_o successive_o force_v out_o by_o a_o fresh_a supply_n of_o spirit_n send_v in_o by_o every_o systole_n of_o the_o brain_n and_o so_o muscular_a motion_n will_v not_o be_v voluntary_a but_o accidental_a that_o this_o matter_n be_v not_o intelligent_a be_v prove_v sufficient_o intelligent_a because_o to_o allow_v that_o this_o act_n as_o it_o receive_v instinct_n from_o the_o brain_n be_v to_o allow_v a_o subordinate_a soul_n which_o act_v proprià _fw-la facultate_fw-la in_o every_o tendon_n which_o be_v false_a for_o a_o intelligent_a faculty_n in_o a_o tendon_n which_o must_v act_v according_a to_o the_o dictate_v of_o the_o principal_a soul_n can_v be_v suppose_v to_o be_v a_o faculty_n of_o that_o soul_n no_o more_o than_o the_o soul_n of_o a_o disciple_n juratus_fw-la in_o verba_fw-la magistri_fw-la and_o who_o exact_o follow_v the_o dictate_v of_o his_o master_n can_v be_v say_v to_o be_v a_o part_n or_o faculty_n of_o his_o master_n soul_n that_o no_o spirit_n of_o a_o different_a nature_n from_o those_o he_o suppose_v to_o be_v in_o the_o tendon_n brain_n can_v be_v transmit_v from_o the_o brain_n be_v evident_a for_o since_o the_o same_o spirit_n be_v distribute_v through_o all_o the_o nevervous_a channel_n from_o the_o same_o fountain_n the_o brain_n or_o the_o spinal_a marrow_n whatever_o cause_v the_o spirit_n to_o leap_v out_o of_o one_o tendon_n will_v cause_v the_o same_o effect_n in_o all_o and_o all_o the_o muscle_n must_v be_v contract_v at_o the_o same_o instinct_n have_v thus_o confute_v the_o ground_n and_o foundation_n of_o his_o hypothesis_n it_o be_v not_o irrational_a to_o expect_v that_o the_o whole_a superstructure_n shall_v fall_v i_o shall_v only_o further_o take_v notice_n first_o fiber_n that_o if_o active_a principle_n of_o another_o nature_n be_v heap_v up_o in_o the_o fleshy_a fiber_n by_o degree_n they_o will_v be_v so_o stuff_v and_o swell_v up_o that_o there_o will_v be_v no_o room_n for_o the_o entrance_n of_o elastic_a spirit_n from_o the_o tendon_n but_o they_o themselves_o will_v rather_o by_o reason_n of_o their_o quantity_n be_v force_v into_o the_o tendinous_a fiber_n second_o that_o it_o will_v be_v absurd_a to_o imagine_v tendon_n how_o these_o two_o spirit_n after_o so_o intimate_v a_o commixture_n as_o will_v be_v produce_v by_o a_o strong_a fermentation_n can_v be_v so_o easy_o separate_v that_o the_o one_o shall_v sudden_o run_v back_o into_o the_o tendon_n leave_v the_o other_o behind_o in_o the_o fleshy_a fiber_n for_o when_o two_o liquor_n of_o a_o different_a nature_n and_o who_o minute_n and_o subtle_a particle_n have_v a_o different_a motion_n be_v mix_v together_o by_o a_o mutual_a fermentation_n be_v produce_v so_o intimate_a a_o mixture_n that_o it_o be_v impossible_a to_o separate_v the_o one_o from_o the_o other_o sincere_a because_o by_o a_o mutual_a collision_n of_o different_a particle_n both_o must_v needs_o in_o some_o measure_n be_v alter_v and_o degenerate_a from_o their_o pristine_a state_n so_o that_o if_o the_o pure_a part_n of_o these_o spirit_n remain_v shall_v run_v back_o into_o the_o tendon_n they_o will_v be_v disagreeable_a to_o and_o different_a from_o those_o pure_a spirit_n send_v from_o the_o brain_n and_o will_v infect_v the_o storehouse_n with_o such_o a_o fermentative_a taint_n that_o as_o new_a supply_v be_v lay_v down_o by_o the_o nerve_n fresh_a explosion_n and_o contraction_n of_o the_o muscle_n must_v follow_v three_o to_o help_v the_o retrocession_n of_o these_o spirit_n into_o the_o tendinous_a fiber_n dr._n willis_n will_v have_v the_o fiber_n of_o the_o invest_n membrance_n to_o contract_n but_o i_o shall_v rather_o think_v that_o they_o will_v contract_v at_o the_o same_o time_n with_o the_o muscle_n if_o the_o instinct_n be_v carry_v through_o the_o same_o nervous_a channel_n with_o the_o spirit_n because_o as_o he_o say_v they_o be_v first_o lay_v down_o in_o the_o membrane_n and_o thence_o convey_v to_o the_o tendon_n mr._n cowper_n in_o the_o introduction_n to_o his_o myotomia_fw-la reformata_fw-la examine_v suspect_v that_o
the_o same_o time_n be_v drive_v back_o with_o a_o equal_a speed_n from_o the_o antagonist_n muscle_n into_o the_o room_n of_o the_o former_a which_o be_v transmit_v from_o the_o brain_n to_o the_o contract_a muscle_n to_o avoid_v a_o vacuum_n that_o the_o nervous_a duct_n as_o well_o as_o carnous_a fiber_n be_v always_o water_v with_o a_o fluid_a allow_v and_o that_o the_o nervous_a liquor_n equal_o flow_v into_o the_o branch_n of_o all_o the_o nerve_n according_a to_o their_o proportion_n be_v beyond_o contradiction_n but_o if_o we_o allow_v the_o common_a postulatum_fw-la we_o must_v also_o conclude_v that_o the_o animal_n fluid_n be_v intelligent_a and_o there_o will_v follow_v the_o same_o difficulty_n as_o be_v before_o mention_v about_o the_o leap_v forth_o of_o spirit_n out_o of_o dr._n willis_n his_o tendinous_a receptacle_n where_o i_o have_v give_v sufficient_a reason_n to_o reject_v this_o postulatum_fw-la as_o impossible_a moreover_o if_o it_o be_v possible_a autagonist_n for_o so_o much_o of_o this_o animal_n fluid_n as_o be_v requisite_a to_o distend_v the_o carnous_a fiber_n to_o be_v conveige_v in_o so_o short_a a_o time_n as_o muscular_a motion_n follow_v our_o appetite_n through_o the_o small_a branch_n of_o the_o nerve_n yet_o it_o will_v be_v altogether_o unconceivable_a how_o it_o shall_v flow_v back_o from_o the_o antagonist_n thus_o contrary_a to_o the_o course_n of_o circulation_n but_o the_o reason_n he_o give_v be_v partly_o this_o to_o avoid_v a_o vacuum_n this_o be_v a_o most_o stupendous_a sort_n of_o a_o motion_n at_o the_o same_o time_n that_o the_o liquid_a be_v force_v into_o the_o one_o muscle_n it_o run_v direct_o opposite_a from_o the_o antagonist_n which_o be_v very_o irregular_a and_o unlikely_a beside_o i_o can_v understand_v how_o it_o come_v to_o pass_v vacuum_n that_o the_o animal_n fluid_n be_v so_o much_o force_v out_o of_o the_o branch_n of_o the_o nerve_n lead_v to_o the_o muscle_n to_o be_v contract_v as_o to_o leave_v a_o vacuum_n for_o the_o reception_n of_o liquid_n from_o the_o antagonist_n but_o if_o a_o emptiness_n or_o vacuum_n can_v be_v so_o make_v the_o fluid_n will_v as_o soon_o be_v draw_v back_o again_o out_o of_o the_o muscle_n into_o which_o our_o appetite_n direct_v they_o to_o fill_v that_o empty_a space_n as_o out_o of_o the_o antagonist_n to_o prevent_v a_o objection_n against_o his_o supposition_n that_o the_o fluid_n run_v back_o again_o from_o the_o antagonist_n he_o think_v he_o have_v answer_v it_o already_o but_o very_o insufficient_o he_o say_v if_o it_o be_v say_v that_o the_o reflux_n be_v oppose_v by_o the_o constant_a direct_a motion_n it_o be_v easy_a to_o reply_v that_o it_o be_v slow_a direct_a motion_n be_v easy_o repel_v by_o the_o violent_a impulse_n of_o the_o forcible_o relaxed_a muscle_n i_o must_v confess_v it_o be_v no_o piece_n of_o difficulty_n to_o make_v such_o a_o answer_n but_o the_o reply_n seem_v not_o so_o easy_o to_o give_v satisfaction_n i_o will_v fain_o know_v how_o the_o antagonist_n come_v to_o be_v so_o forcible_o relax_v as_o by_o a_o violent_a impulse_n to_o overpower_v the_o direct_a motion_n for_o the_o direct_a motion_n can_v be_v so_o weak_a as_o to_o be_v easy_o overcome_v and_o since_o the_o animal_n fluid_n as_o he_o call_v it_o be_v continual_o drive_v by_o the_o pulsation_n of_o the_o heart_n through_o the_o brain_n or_o spinal_a marrow_n into_o the_o nerve_n whatever_o repel_v the_o direct_a motion_n must_v be_v of_o equal_a if_o not_o great_a force_n than_o the_o systole_n of_o the_o heart_n he_o beg_v leave_v to_o ask_v how_o when_o another_o bend_v his_o arm_n against_o his_o will_n the_o muscle_n become_v tumid_a as_o when_o voluntary_o contract_v this_o question_n do_v not_o at_o all_o confirm_v his_o hypothesis_n but_o on_o the_o contrary_n plead_v against_o it_o it_o do_v not_o confirm_v it_o because_o he_o do_v not_o account_n for_o the_o phaenomenon_n nor_o give_v a_o reason_n agreeable_a to_o his_o opinion_n but_o leave_v the_o thing_n bare_o without_o explanation_n it_o plead_v against_o he_o because_o according_a to_o his_o opinion_n the_o muscle_n instead_o of_o grow_v tumid_a ought_v violent_o to_o relax_v at_o least_o to_o endeavour_v a_o relaxation_n and_o not_o contrary_a to_o the_o appetite_n to_o run_v into_o a_o muscle_n against_o our_o will_n for_o he_o say_v at_o the_o same_o time_n that_o the_o muscle_n to_o be_v contract_v grow_v tumid_a the_o antagonist_n by_o a_o violent_a relaxation_n drive_v out_o the_o fluid_a contain_v in_o they_o so_o that_o it_o will_v follow_v that_o at_o the_o same_o time_n we_o endeavour_v to_o keep_v our_o arm_n unbend_v by_o strive_v to_o keep_v the_o one_o muscle_n contract_v at_o the_o same_o time_n we_o ought_v to_o endeavour_v a_o relaxation_n of_o the_o antagonist_n and_o though_o that_o force_n which_o bend_v our_o arm_n do_v resist_v the_o voluntary_a contraction_n of_o the_o muscle_n yet_o there_o will_v nothing_o hinder_v the_o voluntary_a relaxation_n of_o that_o muscle_n which_o be_v the_o antagonist_n but_o the_o slow_a direct_a motion_n as_o he_o call_v it_o but_o here_o i_o humble_o take_v leave_v to_o ask_v whether_o there_o be_v not_o a_o great_a deal_n of_o difference_n betwixt_o a_o muscle_n that_o be_v thus_o tumid_a and_o one_o that_o be_v contract_v for_o although_o a_o muscle_n can_v but_o be_v tumid_a when_o contract_v yet_o it_o may_v be_v tumid_a though_o not_o contract_v i_o mean_v as_o it_o be_v in_o muscular_a motion_n i_o have_v indeed_o oft_o take_v notice_n that_o when_o my_o arm_n have_v be_v bend_v against_o my_o will_n the_o muscle_n become_v tumid_a but_o not_o as_o in_o muscular_a motion_n for_o when_o a_o muscle_n be_v voluntary_o contract_v it_o be_v hard_a and_o tumid_a but_o when_o my_o arm_n be_v bend_v against_o my_o will_n it_o be_v far_o more_o soft_a and_o though_o tumid_a yet_o very_o little_o contract_v since_o the_o reason_n why_o the_o muscle_n grow_v thus_o tumid_a can_v be_v account_v for_o by_o this_o hypothesis_n i_o shall_v explain_v it_o hereafter_o have_v thus_o examine_v and_o i_o hope_v confute_v the_o aforementioned_a opinion_n i_o shall_v in_o the_o next_o place_n brief_o consider_v the_o fabric_n of_o a_o muscle_n the_o immediate_a instrument_n of_o motion_n anatomist_n describe_v the_o fabric_n of_o the_o muscle_n of_o the_o body_n divide_v they_o into_o simple_a compound_v and_o more_o compound_v as_o also_o every_o muscle_n into_o three_o part_n the_o head_n the_o belly_n and_o the_o tail_n they_o acquaint_v you_o how_o the_o belly_n be_v compose_v of_o several_a fasciculi_fw-la of_o fleshy_a fiber_n which_o lie_v parallel_v to_o each_o other_o etc._n etc._n of_o which_o enough_o may_v be_v see_v with_o a_o full_a description_n of_o each_o sort_n of_o muscle_n in_o the_o original_a author_n i_o shall_v omit_v the_o repetition_n here_o and_o only_o take_v notice_n of_o its_o fabric_n as_o far_o as_o relate_v to_o my_o hypothesis_n every_o muscle_n be_v endow_v with_o opposite_a tendon_n muscle_n which_o be_v compose_v of_o several_a fasciculi_fw-la of_o fiber_n lie_v parallel_n to_o each_o other_o these_o fiber_n be_v strict_o join_v together_o compose_v a_o strong_a tenacious_a and_o firm_a tendon_n but_o be_v separate_v one_o from_o another_o be_v more_o fragile_a and_o subject_a to_o be_v easy_o break_v and_o pull_v in_o piece_n they_o be_v continue_v from_o each_o tendon_n to_o its_o opposite_a the_o interstice_n of_o the_o fiber_n thus_o separate_v be_v fill_v with_o the_o branch_n and_o extremity_n of_o vessel_n the_o major_a part_n of_o which_o be_v sanguiferous_a so_o that_o the_o fiber_n continue_v through_o the_o belly_n of_o a_o muscle_n be_v obscure_v by_o the_o colour_n of_o the_o blood_n seem_v to_o degenerate_v from_o the_o tendinous_a fiber_n and_o therefore_o be_v call_v fleshy_a these_o fiber_n as_o they_o be_v continue_v from_o each_o opposite_a tendon_n so_o also_o there_o be_v a_o continue_a cavity_n from_o one_o end_n of_o every_o fiber_n to_o the_o other_o which_o be_v partition_a by_o several_a transverse_n and_o perforated_a membrane_n every_o fiber_n according_a to_o dr._n croone_a resemble_v a_o continue_a series_n of_o bladder_n open_v one_o into_o another_o by_o a_o intumescence_n of_o these_o fiber_n they_o be_v contract_v in_o length_n muscle_n and_o by_o a_o contraction_n of_o their_o longitude_n each_o tendon_n be_v draw_v near_o to_o its_o opposite_a which_o be_v the_o formal_a cause_n of_o muscular_a motion_n as_o far_o as_o can_v be_v make_v evident_a by_o autopsie_n this_o be_v so_o unanimous_o assent_v to_o and_o so_o apparent_a to_o the_o naked_a eye_n that_o it_o require_v no_o further_a proof_n as_o for_o the_o efficient_a cause_n of_o muscular_a motion_n before_o they_o can_v be_v sufficient_o show_v we_o must_v inquire_v how_o many_o sort_n of_o vessel_n be_v implant_v into_o
each_o muscle_n which_o according_a to_o anatomist_n be_v four_o nerve_n artery_n vein_n and_o lymphduct_n muscle_n the_o nerve_n and_o artery_n furnish_v the_o muscle_n with_o spirit_n and_o blood_n the_o vein_n and_o lymphduct_n carry_v back_o the_o superfluity_n of_o blood_n and_o lympha_fw-la the_o branch_n of_o all_o these_o vessel_n be_v minutely_o distribute_v through_o the_o whole_a muscle_n distribution_n and_o by_o a_o intermixture_n and_o texture_n of_o the_o most_o minute_n and_o subtle_a branch_n of_o the_o same_o be_v form_v that_o substance_n which_o fill_v up_o the_o interstice_n of_o the_o fiber_n and_o which_o denominate_v the_o whole_a belly_n of_o a_o muscle_n fleshy_a the_o colour_n of_o these_o vessel_n as_o of_o all_o other_o be_v without_o doubt_n white_a but_o by_o the_o content_n of_o the_o sanguiferous_a vessel_n the_o whole_a belly_n of_o a_o muscle_n be_v colour_v red._n the_o termination_n of_o these_o vessel_n be_v so_o minute_n and_o small_a so_o brittle_a and_o subject_a to_o be_v break_v that_o it_o be_v as_o difficult_a to_o trace_v and_o find_v their_o termination_n and_o insertion_n as_o to_o divide_v a_o hair_n into_o a_o hundred_o part_n and_o though_o many_o thing_n be_v make_v visible_a by_o the_o help_n of_o microscope_n which_o be_v otherwise_o too_o subtle_a to_o be_v discern_v and_o discover_v by_o the_o naked_a eye_n yet_o i_o be_o not_o without_o reason_n persuade_v that_o the_o termination_n of_o these_o vessel_n can_v be_v perceive_v by_o the_o help_n of_o a_o microscope_n some_o indeed_o whatever_o they_o think_v be_v probable_a lest_o it_o shall_v not_o be_v credit_v present_o strenuous_o affirm_v they_o see_v it_o with_o their_o microscope_n and_o so_o easy_o impose_v on_o those_o that_o less_o inquire_v after_o truth_n themselves_o but_o take_v it_o on_o trust_n from_o other_o and_o perhaps_o prevent_v those_o not_o so_o exquisite_o skilled_a in_o microscope_n from_o make_v any_o further_a search_n after_o truth_n i_o shall_v not_o here_o say_v that_o what_o i_o propose_v concern_v the_o termination_n of_o these_o vessel_n be_v see_v with_o any_o microscope_n but_o shall_v declare_v my_o opinion_n in_o this_o matter_n too_o subtle_a for_o any_o microscope_n but_o reason_n it_o be_v impossible_a for_o any_o one_o to_o understand_v the_o true_a reason_n of_o muscular_a motion_n gland_n unless_o first_o acquaint_v with_o the_o distribution_n of_o these_o vessel_n and_o their_o content_n first_o i_o conceive_v that_o as_o the_o nerve_n artery_n and_o vein_n be_v all_o distribute_v through_o a_o muscle_n so_o it_o be_v but_o reasonable_a to_o conclude_v that_o their_o minute_n and_o subtle_a twig_n be_v all_o before_o they_o terminate_v interweave_v and_o mix_v with_o one_o another_o and_o if_o so_o it_o will_v not_o be_v absurd_a to_o imagine_v that_o they_o all_o end_n as_o it_o be_v in_o small_a and_o diminutive_a gland_n and_o if_o the_o end_n of_o the_o vessel_n be_v so_o small_a that_o their_o termination_n can_v be_v perceive_v by_o a_o microscope_n these_o glandule_n compose_v of_o the_o invisible_a end_n of_o the_o aforesaid_a vessel_n must_v needs_o be_v very_o small_a and_o fine_a and_o consequent_o may_v not_o be_v perceive_v by_o the_o help_n of_o extraordinary_a microscope_n from_o these_o glandule_n thus_o form_v be_v derive_v short_a duct_n or_o passage_n for_o the_o conveyance_n of_o a_o subtle_a liquor_n out_o of_o the_o aforesaid_a glandule_n into_o the_o cavity_n of_o the_o carnous_a fiber_n this_o passage_n very_o likely_a may_v be_v compose_v of_o the_o external_a arterial_a coat_n into_o the_o cavity_n of_o the_o carnous_a fiber_n beside_o these_o duct_n the_o twig_n of_o the_o lymphduct_n be_v also_o insert_v to_o carry_v back_o a_o superfluous_a lympha_fw-la if_o any_o one_o think_v it_o improper_a or_o absurd_a to_o assert_v prove_v that_o these_o vessel_n do_v thus_o terminate_v as_o if_o it_o be_v in_o small_a glandule_n let_v he_o but_o consider_v what_o a_o gland_n be_v and_o how_o it_o be_v compose_v and_o he_o will_v not_o think_v the_o conclusion_n irrational_a for_o a_o gland_n be_v nothing_o else_o be_v but_o a_o composition_n of_o a_o infinite_a number_n of_o small_a and_o diminutive_a vessel_n several_a and_o most_o of_o which_o have_v communication_n one_o with_o another_o which_o gland_n so_o compose_v be_v as_o a_o storehouse_n to_o receive_v and_o contain_v a_o certain_a liquor_n till_o necessity_n require_v or_o its_o quantity_n cause_v a_o exclusion_n of_o it_o and_o this_o seem_v plain_o to_o be_v favour_v by_o dr._n ridley_n when_o he_o say_v that_o the_o whole_a body_n be_v a_o continuity_n of_o vessel_n ad_fw-la infinitum_fw-la now_o if_o a_o gland_n consist_v of_o a_o infinite_a number_n of_o small_a vessel_n and_o if_o the_o branch_n of_o nerve_n vein_n and_o artery_n be_v divide_v before_o they_o terminate_v into_o a_o innumerable_a number_n of_o most_o invisible_a twig_n as_o be_v most_o certain_a when_o from_o one_o twig_n of_o each_o sort_n be_v derive_v a_o vast_a number_n and_o all_o these_o so_o derive_v be_v mix_v and_o interweave_v one_o with_o another_o why_o may_v we_o not_o say_v at_o least_o metaphorical_o since_o they_o in_o their_o distribution_n imitate_v the_o composition_n of_o gland_n that_o they_o terminate_v in_o small_a glandule_n some_o perhaps_o will_v ask_v how_o must_v we_o discover_v these_o gland_n malpigius_n have_v observe_v the_o liver_n to_o be_v compose_v of_o cluster_n of_o gland_n hang_v at_o the_o extremity_n of_o the_o large_a vessel_n like_v so_o many_o bunch_n of_o grape_n and_o the_o gland_n in_o other_o part_n be_v apparent_a but_o in_o a_o muscle_n we_o can_v discern_v no_o such_o thing_n for_o it_o especial_o when_o boil_v part_n into_o distinct_a carnous_a fiber_n to_o which_o i_o answer_v discern_v that_o those_o gland_n be_v nothing_o else_o but_o a_o composition_n of_o the_o end_n of_o import_v and_o export_v vessel_n and_o the_o reason_n why_o we_o can_v discern_v the_o same_o in_o a_o muscle_n be_v this_o because_o the_o extremity_n of_o the_o vessel_n be_v so_o fine_a and_o consequent_o so_o brittle_a and_o be_v contain_v in_o the_o interstice_n of_o so_o strong_a and_o firm_a fiber_n that_o whenever_o we_o endeavour_v a_o separation_n of_o the_o fiber_n the_o glandule_n be_v tear_v away_o from_o the_o vessel_n from_o which_o they_o be_v derive_v whereas_o the_o fiber_n which_o run_v transverse_v the_o liver_n easy_o crumble_v away_o be_v much_o more_o weak_a and_o less_o numerous_a the_o reason_n why_o the_o muscular_a fiber_n be_v so_o much_o strong_a than_o those_o that_o run_v through_o the_o liver_n be_v apparent_a enough_o viz._n because_o the_o former_a be_v the_o instrument_n of_o motion_n and_o consequent_o there_o lie_v a_o great_a stress_n of_o they_o than_o on_o the_o latter_a which_o serve_v to_o make_v the_o part_n a_o little_a more_o compact_a and_o to_o keep_v the_o outward_a coat_n from_o be_v loose_a upon_o its_o circumference_n now_o because_o it_o be_v impossible_a to_o separate_v and_o remove_v these_o muscular_a fiber_n so_o as_o to_o leave_v the_o sanguiferous_a vessel_n as_o entire_a as_o will_v be_v requisite_a for_o the_o exact_a and_o certain_a discovery_n of_o their_o termination_n and_o because_o it_o be_v certain_a that_o these_o vessel_n be_v divide_v and_o subdivide_v ad_fw-la minimum_fw-la that_o they_o be_v interweave_v one_o with_o another_o and_o that_o a_o gland_n be_v nothing_o else_o but_o a_o composition_n of_o vessel_n we_o may_v rational_o conclude_v they_o all_o terminate_v in_o diminutive_a gland_n the_o nerve_n vein_n and_o artery_n compose_v and_o end_v in_o these_o gland_n i_o shall_v next_o inquire_v to_o what_o end_n they_o do_v all_o thus_o meet_v together_o the_o use_n of_o the_o nerve_n in_o these_o be_v the_o same_o as_o in_o other_o part_n nerve_n viz._n to_o convey_v a_o spirituo-saline_a liquor_n from_o the_o brain_n which_o spirit_n be_v volatile_a and_o apt_a to_o ferment_n when_o mix_v with_o a_o liquor_n of_o a_o contrary_a nature_n be_v continual_o send_v by_o the_o systole_n of_o the_o brain_n into_o all_o the_o muscle_n of_o the_o body_n and_o be_v lay_v down_o forcible_o in_o the_o aforesaid_a diminutive_a gland_n gland_n do_v there_o meet_v with_o arterious_a blood_n drive_v in_o by_o every_o contraction_n of_o the_o heart_n which_o two_o liquor_n strong_o ferment_v together_o the_o animal_n spirit_n do_v by_o a_o attrition_n subtilise_fw-fr attenuate_v and_o rarify_v those_o particle_n of_o the_o succus_fw-la nutritius_n supply_v from_o the_o mass_n of_o blood_n by_o which_o mean_v their_o own_o be_v much_o dull_v and_o become_v less_o active_a for_o the_o future_a and_o by_o a_o mixture_n of_o these_o animal_n spirit_n with_o the_o rarefy_v succus_fw-la nutritius_n result_v a_o liquor_n different_n from_o succus_fw-la and_o of_o a_o middle_a state_n betwixt_o the_o animal_n spirit_n and_o the_o