spoon_n and_o cause_n no_o more_o effect_n than_o oil_n of_o olive_n and_o spirit_n of_o sal_fw-la amenoniack_a take_v inward_o one_o act_v too_o soft_o lazy_o and_o greasy_o to_o cause_v any_o brisk_a and_o agreeable_a ovation_n of_o the_o spirit_n and_o the_o other_o too_o rude_o sting_v the_o membrane_n therefore_o we_o must_v proceed_v in_o our_o enquiry_n four_o opium_n have_v a_o sort_n of_o resinous_n sulphur_n that_o be_v loose_a and_o not_o unite_v with_o the_o volatile_a salt_n which_o plain_o appear_v 1._o because_o if_o you_o dissolve_v opium_n in_o water_n cold_a or_o hot_a or_o any_o watery_a menstruum_fw-la you_o will_v find_v a_o good_a quantity_n of_o rosin_n undissolved_a at_o bottom_n while_o the_o volatile_a salt_n be_v all_o or_o most_o dissolve_v in_o the_o water_n especial_o if_o the_o water_n be_v often_o repeat_v and_o quite_o separate_v from_o the_o resinous_n part_v which_o subside_v without_o any_o more_o trouble_n which_o show_v that_o the_o volatile_a salt_n and_o it_o be_v not_o combine_v but_o in_o a_o very_a loose_a and_o distinct_a manner_n 2._o because_o if_o you_o first_o dissolve_v opium_n in_o spirit_n of_o wine_n which_o imbibe_v the_o rosin_n it_o be_v easy_o again_o precipitate_v by_o plain_a water_n leave_v behind_o it_o all_o or_o most_o of_o the_o volatile_a salt_n in_o the_o form_n of_o a_o red_a tincture_n in_o the_o menstruum_fw-la as_o it_o do_v also_o in_o the_o former_a case_n note_v that_o the_o resinous_n part_n of_o opium_n have_v no_o effect_n as_o a_o opiate_n for_o if_o it_o be_v well_o wash_v with_o water_n as_o be_v say_v it_o have_v no_o operation_n of_o that_o kind_n or_o so_o little_a that_o it_o be_v not_o worth_a the_o mind_v but_o all_o the_o virtue_n specific_a taste_n smell_v etc._n etc._n be_v carry_v away_o in_o that_o red_a tincture_n which_o have_v all_o the_o good_a effect_n of_o opium_n as_o experience_n assure_v we_o 3._o because_o if_o opium_n be_v very_o much_o torrefy_v most_o of_o the_o volatile_a salt_n be_v evaporate_v and_o with_o it_o most_o if_o not_o all_o the_o virtue_n of_o opium_n but_o the_o rosin_n remain_v as_o a_o deadish_a stuff_n in_o respect_n of_o the_o good_a effect_n of_o opium_n though_o it_o be_v as_o shall_v be_v prove_v the_o producer_n of_o the_o ill_a effect_n thereof_o therefore_o this_o rosin_n must_v be_v whole_o reject_v five_o the_o red_a tincture_n aforesaid_a have_v all_o or_o most_o of_o the_o volatile_a salt_n in_o it_o 1._o because_o water_n be_v the_o proper_a menstruum_fw-la for_o saline_n thing_n and_o that_o the_o tincture_n reduce_v to_o a_o extract_n give_v very_o much_o in_o moist_a wether_n which_o quality_n it_o must_v have_v from_o the_o volatile_a salt_n because_o it_o have_v very_o little_o fix_v salt_n 2._o because_o the_o specific_a bitterness_n which_o proceed_v from_o volatile_a salt_n and_o oily_a part_n be_v whole_o in_o that_o red_a tincture_n 3._o because_o that_o tincture_n have_v also_o the_o specific_a rankness_n of_o smell_n that_o the_o volatile_a salt_n as_o be_v show_v give_v the_o opium_n by_o the_o help_n of_o some_o oily_a part_n 4._o because_o that_o tincture_n reduce_v to_o a_o extract_n have_v the_o bite_a taste_n of_o opium_n which_o as_o be_v show_v proceed_v from_o its_o volatile_a salt_n 5._o because_o that_o extract_n incides_fw-la discuss_n resolve_n be_v psilothrick_n titillate_n to_o venery_n cause_v itch_n in_o the_o skin_n acrimonious_a sweat_v etc._n etc._n all_o which_o be_v as_o be_v show_v the_o effect_n of_o volatile_a salt_n but_o what_o need_v i_o insist_v so_o much_o upon_o its_o effect_n to_o prove_v it_o when_o 6._o it_o appear_v by_o crystalization_n of_o the_o say_a tincture_n after_o it_o have_v be_v evaporate_v to_o a_o due_a degree_n that_o it_o contain_v the_o volatile_a salt_n in_o it_o which_o in_o a_o cool_a place_n shoot_v to_o elegant_a crystal_n and_o that_o 7._o it_o be_v find_v therein_o by_o chemical_a operation_n by_o fire_n six_o the_o say_a tincture_n be_v oleose_v 1._o because_o the_o redness_n of_o the_o tincture_n must_v be_v from_o oily_a part_n for_o pure_a sincere_a volatile_a salt_n give_v no_o such_o tincture_n 2._o because_o it_o be_v bitter_a one_o ingredient_n of_o which_o taste_n be_v ever_o oily_a part_n as_o be_v say_v 3._o because_o of_o its_o rank_a smell_n like_o sem._n viril_n which_o prove_v it_o to_o be_v sulphureous_a for_o the_o volatile_a salt_n alone_o have_v only_o a_o quick_a smell_n or_o urinous_a at_o far_a 4._o because_o it_o be_v of_o a_o hot_a taste_n when_o reduce_v to_o a_o extract_n which_o heat_v of_o taste_n consider_v distinct_o from_o its_o pungent_a or_o bite_a taste_n must_v be_v from_o sulphureous_a or_o oily_a part_n 5._o because_o spirit_n of_o wine_n and_o other_o spirituosulphureous_a menstruum_n do_v ready_o dissolve_v it_o when_o reduce_v to_o a_o extract_n 6._o because_o the_o extract_n soften_v with_o dry_a warmth_n as_o sulphureous_a or_o oily_a thing_n do_v 7._o because_o a_o true_a sal-volatile-oleosum_a wherein_o the_o volatile_a salt_n and_o oily_a part_n be_v intimate_o combine_v as_o you_o find_v in_o all_o blood_n tincture_n of_o several_a plant_n that_o have_v such_o a_o sal-volatile-oleosum_a be_v red_a 8._o because_o it_o can_v not_o otherwise_o so_o fine_o please_v the_o membrane_n cause_n sleep_n compose_v the_o spirit_n etc._n etc._n if_o it_o be_v all_o volatile_a salt_n which_o be_v whole_o pungent_a and_o acrimonious_a mighty_o oppose_v sleep_n and_o cause_v a_o great_a stir_n in_o the_o blood_n and_o spirit_n but_o as_o i_o say_v as_o to_o its_o volatile_a salt_n what_o need_v i_o insist_v upon_o its_o effect_n when_o 10._o it_o be_v inflammability_n after_o it_o be_v reduce_v to_o a_o extract_n and_o dry_v put_v it_o out_o of_o all_o question_n and_o that_o 11._o a_o oil_n may_v be_v separate_v from_o the_o volatile_a salt_n though_o not_o without_o trouble_n because_o that_o as_o be_v requisite_a to_o complete_a it_o in_o the_o high_a degree_n seven_o the_o oily_a part_n and_o volatile_a salt_n be_v very_o intimate_o and_o strict_o combine_v as_o fair_o appear_v 1._o by_o the_o difficulty_n to_o separate_v they_o 2._o by_o the_o redness_n of_o the_o tincture_n as_o in_o blood_n etc._n etc._n for_o when_o oily_a or_o sulphureous_a particle_n be_v loose_a therein_o they_o make_v either_o a_o white_a colour_n as_o the_o rosin_n do_v in_o the_o drop_n that_o fall_v out_o of_o the_o incision_n in_o the_o head_n of_o the_o poppy_n which_o be_v milk_n white_a or_o leave_v the_o volatile_a spirit_n perspicuous_a as_o in_o a_o sort_n of_o artificial_a sal._n volatile-oleosum_a that_o be_v sell_v at_o the_o apothecary_n shop_n in_o london_n 3._o because_o it_o impart_v its_o tincture_n which_o depend_v upon_o both_o to_o all_o menstruum_n 4._o because_o it_o impart_v its_o virtue_n which_o depend_v upon_o both_o to_o all_o menstruum_n 5._o because_o it_o impart_v its_o specific_a smell_n which_o depend_v upon_o both_o to_o all_o menstruumt_v 6._o because_o it_o impart_v its_o specific_a hot_a and_o bite_a taste_n which_o depend_v upon_o both_o the_o oily_a and_o volatile_a particle_n to_o all_o menstruum_n 7._o because_o it_o will_v hold_v its_o virtue_n many_o year_n which_o it_o can_v not_o if_o the_o volatile_a salt_n and_o oily_a part_n be_v not_o very_o strict_o combine_v 8._o because_o that_o notwithstanding_o the_o digestion_n at_o stomach_n it_o have_v hold_v its_o specific_a virtue_n smell_v and_o taste_n after_o it_o have_v be_v in_o it_o 4_o 5_o 6_o 7_o 8_o 9_o 10_o 11_o 12_o 18_o or_o more_o hour_n as_o appear_v by_o its_o operate_n so_o long_o and_o afteward_n its_o be_v vomit_v up_o with_o the_o same_o taste_n and_o smell_v that_o it_o have_v at_o first_o than_o which_o there_o can_v be_v a_o great_a argument_n 9_o because_o it_o have_v be_v carry_v off_o by_o stool_n which_o have_v its_o specific_a smell_n after_o many_o hour_n remain_v in_o the_o stomach_n 10._o because_o its_o operation_n in_o general_n last_v long_o charas_fw-la mention_n one_o that_o it_o operate_v with_o for_o about_o 30_o hour_n and_o wedelius_n another_o who_o opium_n cause_v to_o vomit_v constant_o about_o 18_o hour_n after_o it_o be_v take_v 11._o because_o it_o have_v its_o effect_n upon_o the_o venereal_a membrane_n after_o it_o have_v pass_v the_o digestion_n at_o stomach_n the_o effect_n of_o the_o choler_n and_o succus_fw-la pancreatus_fw-la in_o the_o duodenum_fw-la be_v strain_v through_o the_o coat_n of_o the_o intestine_n into_o the_o lacteal_v and_o through_o the_o glandule_n of_o the_o mesentery_n mix_v and_o circulate_v with_o the_o blood_n etc._n etc._n 12._o because_o after_o all_o that_o it_o have_v its_o effect_n upon_o the_o skin_n by_o cause_v a_o itch_a therein_o 13._o because_o it_o not_o only_a cause_n acrimonious_a sweat_v but_o such_o as_o evident_o smell_v thereof_o
increase_v more_o and_o more_o and_o make_v one_o more_o and_o more_o remote_a from_o wake_v 4._o why_o shall_v warm_a bath_n fomentation_n feetwash_n head-washes_a warm_a moist_a wether_n the_o act_n of_o venery_n the_o pleasure_n of_o sweet_a melody_n gentle_a rub_v of_o the_o head_n in_o a_o pleasant_a manner_n scratch_v the_o back_n where_o it_o itch_v and_o all_o gentle_a pleasure_n that_o be_v consistent_a with_o lie_v or_o sit_v still_o which_o do_v all_o cause_n a_o very_a free_a perspiration_n of_o fume_n at_o the_o pore_n that_o be_v then_o most_o certain_o open_v by_o all_o those_o cause_n as_o may_v be_v prove_v by_o statick_a demonstration_n magnify_v glass_n etc._n etc._n cause_n sleep_n see_v they_o all_o cause_n a_o spend_v of_o the_o fume_n obj._n some_o half-witted_a unthinking_a caviller_n may_v say_v that_o such_o thing_n stir_v up_o the_o vapour_n etc._n etc._n answ._n what_o such_o mean_a by_o vapour_n stir_v be_v not_o easy_o determinable_a but_o this_o i_o know_v that_o all_o stir_n of_o humour_n or_o any_o other_o thing_n hinder_v sleep_n and_o that_o the_o long_o such_o cause_n of_o open_v the_o pore_n and_o consequent_o of_o perspire_a fume_n do_v last_o the_o more_o we_o be_v incline_v by_o they_o to_o sleep_n so_o that_o the_o more_o our_o fume_n have_v be_v spend_v the_o more_o we_o be_v incline_v to_o sleep_v which_o be_v a_o strange_a contradiction_n if_o fume_n be_v the_o cause_n of_o sleep_n i_o can_v but_o smile_v to_o think_v how_o most_o physician_n come_v to_o call_v several_a thing_n vapour_n first_o they_o say_v that_o sleep_n be_v from_o vapour_n then_o call_v every_o thing_n vapour_n right_a or_o wrong_n that_o incline_v we_o to_o sleep_v by_o reason_n of_o that_o false_a supposition_n how_o then_o come_v camphire_n not_o to_o be_v a_o great_a causer_n of_o sleep_n that_o be_v so_o apt_a to_o evaporate_v 5._o fear_v sorrow_n grief_n melancholy_n depression_n of_o spirit_n cold_a etc._n etc._n do_v most_o certain_o close_v the_o pore_n as_o appear_v by_o statick_a experiment_n by_o which_o mean_v vapour_n be_v much_o crowd_v in_o the_o body_n yet_o all_o such_o grievance_n do_v hinder_v sleep_n as_o they_o also_o do_v the_o effect_n of_o opium_n and_o drunkenness_n therefore_o they_o do_v not_o proceed_v from_o fume_n as_o the_o world_n imagine_v for_o then_o these_o thing_n that_o crowd_v in_o the_o fume_n and_o vapour_n will_v promote_v not_o hinder_v sleep_n 6._o if_o fume_n be_v the_o cause_n of_o sleep_n then_o be_v the_o cause_n of_o sleep_n and_o vertigo_n as_o the_o vaporanians_n allow_v the_o same_o it_o follow_v then_o that_o we_o can_v never_o sleep_v without_o a_o vertigo_n 7._o many_o as_o dr._n willis_n say_v eat_v their_o meat_n take_v their_o drink_n etc._n etc._n as_o other_o people_n yet_o do_v not_o sleep_v at_o all_o for_o many_o week_n together_o which_o be_v impossible_a if_o the_o fume_n of_o meat_n and_o drink_v cause_v sleep_n for_o they_o by_o eat_v and_o drink_v must_v have_v those_o fume_n and_o consequent_o sleep_v as_o other_o people_n if_o that_o be_v true_a three_o they_o suppose_v and_o take_v it_o for_o grant_v which_o i_o do_v not_o for_o i_o know_v the_o contrary_a that_o opium_n while_o it_o be_v at_o stomach_n can_v affect_v the_o brain_n etc._n etc._n no_o other_o way_n but_o by_o fume_n which_o be_v a_o most_o groundless_a supposition_n for_o 1._o how_o shall_v a_o lump_n of_o curd_n at_o stomach_n or_o the_o have_v of_o a_o knife_n swallow_v and_o many_o such_o thing_n which_o can_v send_v no_o fume_n to_o the_o head_n cause_n convulsion_n headache_n vertigo_n syncopes_fw-la leipothymy_n of_o the_o whole_a man_n manias_fw-la furor_n etc._n etc._n if_o there_o be_v not_o another_o way_n for_o thing_n to_o affect_v the_o nervosum_fw-la genus_fw-la etc._n etc._n while_n at_o stomach_n beside_o send_v up_o vapour_n to_o do_v it_o but_o of_o this_o matter_n to_o show_v how_o a_o thing_n at_o stomach_n may_v affect_v the_o brain_n and_o the_o whole_a system_n of_o the_o nerve_n etc._n etc._n and_o how_o opium_n do_v it_o without_o fume_n the_o 17_o 18_o 19_o 20_o etc._n etc._n chapter_n will_v show_v you_o at_o large_a therefore_o i_o shall_v say_v no_o more_o of_o this_o at_o present_a for_o it_o be_v fit_a for_o we_o first_o to_o overthrow_v that_o supposition_n of_o fume_n and_o vapour_n before_o we_o establish_v our_o own_o for_o far_a satisfaction_n then_o as_o to_o that_o general_a supposition_n of_o fume_n let_v we_o due_o and_o full_o consider_v thing_n for_o it_o be_v not_o a_o slight_a matter_n to_o proceed_v against_o a_o general_n opinion_n that_o have_v continue_v through_o all_o age_n or_o to_o wipe_v off_o the_o prejudices_fw-la acquire_v thereby_o observe_v 1._o that_o the_o brain_n be_v a_o principal_a part._n 2._o that_o it_o be_v very_o soft_a tender_a and_o next_o to_o a_o fluid_a 3._o that_o very_o small_a fine_a and_o gentle_a thing_n do_v high_o offend_v it_o as_o the_o effluvia_n of_o sweet_a or_o ill-scented_n thing_n cause_v hysterick_a and_o epileptical_a fit_n syncopes_fw-la faint_n etc._n etc._n it_o be_v also_o notorious_a among_o we_o physician_n that_o a_o little_a fume_v scarce_o sensible_a as_o to_o quantity_n or_o quality_n rise_v from_o a_o toe_n finger_n &c_n &c_n and_o arrive_v at_o the_o brain_n cause_v dreadful_a epileptical_a fit_n vertigo_n &c._n &c._n 4._o that_o our_o wise_a and_o provident_a creator_n have_v therefore_o secure_v and_o fortify_v all_o the_o avenue_n of_o the_o brain_n in_o a_o more_o particular_a manner_n by_o several_a circumvallation_n viz._n first_o with_o the_o pia_fw-la mater_fw-la second_o with_o the_o dura_n mater_n call_v so_o from_o its_o hardness_n solidity_n and_o strength_n three_o with_o a_o strong_a skull_n of_o a_o round_a or_o arch_a figure_n four_o with_o the_o pericranium_n all_o which_o belong_v to_o it_o particular_o beside_o other_o integument_n common_a to_o it_o with_o other_o part_n as_o 1._o the_o skin_n 2._o the_o cuticle_n 3._o the_o membrana_fw-la carnosa_fw-la 4._o the_o periostium_fw-la all_o which_o do_v surround_v it_o and_o after_o all_o it_o be_v thatch_v as_o it_o be_v with_o hair_n 5._o that_o the_o same_o providence_n have_v take_v care_n which_o be_v very_o observable_a that_o none_o of_o the_o object_n of_o sensation_n nor_o probable_o any_o particle_n or_o effluvium_fw-la that_o fly_v from_o they_o shall_v ever_o reach_v the_o brain_n but_o only_o bare_a impulse_n and_o they_o not_o immediate_o convey_v but_o by_o the_o intervention_n of_o a_o fine_a tenuious_a soft_a gentle_a and_o most_o agreeable_a aura_n viz._n the_o animal_n spirit_n lest_o any_o offence_n shall_v be_v give_v in_o the_o least_o manner_n to_o this_o most_o tender_a delicate_a principal_a part_n and_o royal_a seat_n of_o the_o soul_n all_o which_o care_n have_v never_o be_v without_o necessity_n for_o god_n and_o nature_n do_v nothing_o in_o vain_a and_o if_o you_o will_v due_o consider_v the_o organ_n of_o sensation_n that_o be_v near_o the_o brain_n you_o will_v find_v that_o they_o be_v contrive_v as_o shutter_n to_o exclude_v all_o extraneous_a particle_n from_o the_o brain_n for_o impulse_n may_v have_v be_v contrive_v without_o their_o intervention_n because_o they_o do_v not_o alter_v or_o improve_v the_o impulse_n receive_v from_o object_n for_o if_o they_o do_v we_o shall_v not_o have_v true_a notice_n of_o thing_n and_o see_v they_o do_v not_o alter_v or_o improve_v the_o impulse_n of_o what_o use_n shall_v they_o be_v but_o to_o exclude_v extraneous_a particle_n eume_n effluvia_n &c._n &c._n for_o instance_n the_o tremulous_a motion_n of_o the_o air_n in_o the_o case_n of_o sound_n will_v have_v as_o true_o hit_v the_o auditory_a nerve_n or_o membrane_n without_o the_o tympan_n and_o very_o often_o much_o true_a without_o it_o because_o of_o the_o several_a fault_n and_o disorder_n that_o it_o be_v liable_a to_o yet_o so_o necessary_a be_v it_o think_v by_o the_o best_a of_o judge_n who_o can_v err_v that_o it_o be_v rather_o to_o be_v place_v there_o with_o all_o its_o inconvenience_n that_o may_v follow_v than_o any_o way_n expose_v the_o brain_n though_o to_o the_o most_o gentle_a of_o body_n viz._n the_o air_n by_o which_o in_o all_o probability_n the_o animal_n spirit_n themselves_o be_v nourish_v or_o sustain_v be_v it_o not_o that_o extraneous_a particle_n or_o air_n will_v offend_v the_o brain_n what_o need_n be_v there_o of_o the_o tympan_n when_o we_o know_v as_o well_o by_o experience_n as_o by_o the_o aforesaid_a reason_n that_o a_o dog_n etc._n etc._n can_v hear_v as_o well_o without_o it_o upon_o the_o first_o take_v it_o off_o but_o that_o the_o hear_v will_v afterward_o decay_v because_o the_o brain_n etc._n etc._n be_v expose_v will_v be_v injure_v what_o be_v evident_a in_o the_o case_n of_o the_o ear_n may_v be_v make_v so_o
the_o spirit_n by_o any_o mean_n for_o there_o be_v nothing_o so_o good_a in_o nature_n but_o will_v do_v it_o if_o use_v undue_o or_o immoderate_o as_o wine_n bread_n milk_n honey_n sugar_n beer_n etc._n etc._n in_o excess_n for_o i_o intend_v that_o it_o do_v not_o do_v it_o when_o due_o and_o moderate_o use_v 1._o that_o which_o refresh_v the_o weary_a and_o high_o prevent_v weariness_n must_v add_v to_o or_o excite_v the_o spirit_n which_o be_v direct_o contrary_a to_o diminish_v or_o disable_n they_o but_o opium_n do_v in_o a_o most_o eminent_a manner_n refresh_v the_o weary_v and_o prevent_v weariness_n therefore_o it_o do_v not_o diminish_v or_o disable_v the_o spirit_n some_o have_v be_v so_o silly_a and_o inadvertent_n as_o to_o object_n that_o it_o refresh_v the_o weary_a only_o by_o sleep_n it_o be_v matter_n of_o fact_n that_o it_o refresh_v they_o whether_o they_o sleep_v or_o no_o and_o that_o without_o fail_v as_o often_o as_o it_o be_v use_v in_o that_o case_n other_o that_o be_v no_o wise_a have_v say_v that_o it_o only_o take_v off_o the_o sense_n of_o weariness_n by_o stupify_a which_o happen_v by_o the_o diminish_n or_o disable_n of_o the_o animal_n spirit_n bare_a insensibleness_n can_v enable_v the_o spirit_n to_o labour_n with_o eminent_a briskness_n and_o alacrity_n as_o man_n most_o certain_o do_v after_o opium_n be_v take_v be_v fine_o enliven_v and_o invigorate_v as_o with_o generous_a wine_n if_o they_o do_v not_o know_v this_o to_o be_v true_a let_v they_o for_o shame_n hold_v their_o tongue_n till_o they_o know_v matter_n of_o fact_n which_o if_o they_o will_v not_o they_o proclaim_v themselves_o to_o be_v idle_a and_o impertinent_a babbler_n but_o if_o they_o will_v patient_o and_o wise_o abstain_v argue_v till_o they_o be_v satisfy_v as_o to_o matter_n of_o fact_n then_o will_v they_o be_v past_a opinion_n and_o hypothesis_n in_o that_o case_n for_o they_o will_v have_v sensible_a and_o certain_a knowledge_n of_o the_o contrary_a and_o the_o truth_n of_o what_o i_o say_v which_o will_v end_v all_o controversy_n and_o precarious_a squabble_n upon_o false_a supposition_n as_o the_o manner_n be_v that_o can_v lead_v they_o to_o what_o be_v right_o but_o by_o mere_a chance_n and_o never_o to_o a_o true_a knowledge_n that_o they_o be_v in_o the_o right_n which_o make_v it_o none_o in_o effect_n for_o they_o can_v do_v nothing_o with_o assurance_n but_o only_o suppose_v and_o hope_v they_o be_v in_o the_o right_n when_o they_o be_v as_o much_o out_o to_o their_o patient_n sorrow_n as_o physician_n have_v be_v in_o the_o cold_a quality_n and_o fume_n of_o opium_n it_o be_v true_a that_o a_o grain_n or_o two_o of_o opium_n will_n if_o a_o man_n compose_v himself_o sit_v or_o lie_v still_o cause_n a_o sleepiness_n equal_a to_o that_o cause_v by_o spend_v the_o spirit_n by_o a_o day_n be_v labour_n but_o spend_v of_o the_o spirit_n be_v not_o the_o only_a no_o nor_o best_a proportion_v or_o more_o adequate_a cause_n thereof_o as_o i_o have_v show_v if_o loss_n of_o spirit_n be_v the_o adequate_a cause_n of_o sleep_n how_o shall_v good_a and_o generous_a wine_n cause_n sleepiness_n after_o that_o eminent_a rate_n as_o it_o do_v in_o most_o people_n how_o shall_v the_o most_o please_a music_n incline_v such_o as_o lie_v or_o sit_v still_o to_o sleep_v but_o if_o one_o dance_n thereto_o it_o make_v he_o more_o lively_a and_o brisk_a than_o ordinary_a the_o like_a exact_o do_v wine_n and_o opium_n if_o man_n lie_v or_o sit_v still_o but_o otherwise_o they_o make_v they_o much_o more_o brisk_a and_o lively_a and_o able_a to_o undergo_v labour_n action_n etc._n etc._n which_o note_n that_o you_o may_v not_o any_o more_o wonder_n that_o enlivener_n and_o exciter_n of_o the_o spirit_n do_v cause_n sleep_v as_o well_o as_o diminisher_n thereof_o and_o observe_v that_o they_o be_v all_o please_a thing_n as_o music_n wine_n and_o opium_n which_o cause_n pleasant_a dream_n pleasant_a watch_n pleasant_a humour_n etc._n etc._n expect_v more_o of_o this_o matter_n in_o the_o follow_a chapter_n and_o all_o by_o degree_n according_a as_o i_o judge_v the_o prejudice_v world_n will_v bear_v thing_n for_o a_o great_a paradox_n how_o true_a soever_o must_v not_o be_v abrupt_o obtrude_v but_o gentle_o and_o gradual_o usher_v in_o by_o insinuate_v reason_v otherwise_o it_o will_v be_v entertain_v like_o a_o rude_a stranger_n that_o contradict_v a_o multitude_n in_o fashion_n and_o custom_n that_o they_o have_v always_o use_v and_o judge_v to_o be_v the_o very_o best_o however_o unblamable_a consider_v that_o if_o opium_n diminish_v or_o disable_v the_o spirit_n proportionable_a to_o the_o sleepiness_n that_o it_o cause_n as_o a_o hard_a day_n be_v labour_n do_v then_o if_o opium_n be_v give_v a_o man_n after_o a_o hard_a day_n be_v labour_n it_o will_v be_v as_o it_o be_v add_v another_o hard_a day_n be_v labour_v to_o cure_v it_o the_o day_n be_v labour_n and_o opium_n impair_n the_o spirit_n alike_o think_v what_o a_o miserable_a condition_n the_o poor_a man_n will_v be_v in_o especial_o if_o sleep_n do_v not_o make_v he_o some_o amends_o it_o will_v be_v such_o as_o be_v utter_o intolerable_a but_o so_o far_o be_v opium_n from_o any_o such_o effect_n that_o it_o refresh_v he_o though_o he_o sleep_v not_o at_o all_o after_o the_o hard_a day_n be_v labour_n and_o not_o only_o so_o but_o will_v enable_v he_o to_o work_v all_o the_o follow_a night_n with_o great_a alacrity_n if_o need_n require_v it_o what_o a_o condition_n will_v those_o be_v in_o who_o take_v a_o drachm_n of_o it_o twice_o a_o day_n for_o 10_o 20_o or_o 30_o year_n nay_o how_o can_v any_o possible_o do_v it_o for_o half_a 10_o day_n if_o a_o grain_n or_o two_o destroy_v the_o spirit_n so_o much_o as_o to_o cause_v sleepiness_n thereby_o as_o hard_a labour_n do_v which_o they_o must_v allow_v that_o assert_v it_o cause_n sleep_v by_o diminish_v or_o disable_n the_o spirit_n but_o some_o may_v say_v though_o very_o inconsiderate_o that_o it_o only_o disable_v they_o for_o the_o time_n of_o its_o operation_n that_o be_v strange_a indeed_o consider_v that_o even_o during_o that_o time_n they_o be_v most_o enable_v to_o work_n or_o labour_n though_o tire_v before_o and_o that_o it_o 2._o cause_n comfort_n refreshment_n ovation_n of_o the_o spirit_n all_o the_o time_n of_o its_o operation_n as_o wine_n moderate_o take_v do_v especial_o if_o people_n keep_v themselves_o in_o action_n labour_n etc._n etc._n otherwise_o indeed_o they_o may_v fall_v asleep_a upon_o the_o comfortable_a satisfaction_n contentation_n of_o mind_n and_o acquiescence_n of_o spirit_n that_o it_o occasion_n as_o wine_n do_v 3._o the_o first_o effect_n that_o we_o find_v of_o opium_n which_o may_v therefore_o probable_o be_v a_o very_a lead_n fundamental_a and_o significant_a effect_n be_v that_o it_o cause_v a_o most_o agreeable_a pleasant_a and_o charm_a sensation_n about_o the_o region_n of_o the_o stomach_n which_o if_o one_o lie_v or_o sit_v still_o incline_v he_o to_o sleep_n if_o not_o it_o make_v he_o gay_a good_a humour_a brave_a etc._n etc._n it_o be_v a_o pleasure_n so_o sweet_a and_o delicious_a that_o though_o i_o endeavour_v to_o express_v it_o by_o the_o ovation_n of_o the_o spirit_n upon_o joy_n a_o good_a genius_n inform_v a_o man_n or_o the_o helmâ—sians_n archaeus_n in_o his_o best_a humour_n or_o a_o continual_a vâ—real_a pleasure_n wine_n drink_v ad_fw-la hilaritatem_fw-la etc._n etc._n yet_o i_o doubt_v all_o my_o way_n of_o express_v it_o do_v come_v short_a of_o the_o charm_a complacency_n that_o it_o cause_n therefore_o if_o wine_n music_n a_o good_a meal_n agreeable_a frication_n of_o the_o head_n or_o back_o the_o sound_n of_o water_n etc._n etc._n do_v incline_v we_o to_o sleep_v by_o the_o pleasure_n thereof_o which_o lull_v and_o soothe_v we_o to_o it_o as_o be_v most_o certain_a if_o we_o sit_v or_o lie_v still_o much_o more_o must_v the_o high_a charm_n of_o opium_n cause_n it_o that_o it_o be_v a_o pleasure_n that_o affect_v by_o one_o of_o our_o sense_n namely_o by_o feel_v be_v indisputable_a for_o it_o be_v not_o a_o pleasure_n of_o the_o eye_n nose_n tongue_n or_o ear_n and_o it_o must_v be_v sensitive_a because_o cause_v by_o matter_n and_o that_o opium_n have_v doubtless_o the_o like_a effect_n upon_o brute_n who_o have_v no_o other_o pleasure_n but_o what_o be_v sensitive_a that_o it_o be_v at_o stomach_n be_v also_o evident_a where_o we_o can_v be_v please_v only_o by_o the_o sense_n of_o feel_v that_o it_o be_v involuntary_a and_o please_v we_o whether_o we_o will_v or_o no_o and_o that_o the_o same_o particle_n excite_v venery_n itch_a etc._n etc._n now_o all_o the_o sense_n especial_o feel_v and_o particular_o that_o at_o stomach_n be_v give_v we_o for_o
impression_n of_o great_a concernment_n may_v escape_v his_o notice_n and_o consequent_o want_v his_o assistance_n by_o way_n of_o defence_n for_o it_o be_v manifest_a that_o when_o his_o attention_n be_v divert_v by_o any_o object_n more_o especial_o by_o such_o as_o mighty_o please_v he_o as_o in_o the_o act_n of_o venery_n and_o other_o pleasure_n especial_o if_o intense_a that_o he_o do_v not_o perceive_v other_o object_n at_o the_o time_n that_o he_o be_v so_o divert_v and_o if_o the_o pleasant_a diversion_n be_v intense_a and_o permanent_a as_o in_o the_o case_n of_o opium_n and_o wine_n drink_v in_o a_o considerable_a quantity_n he_o be_v so_o take_v up_o divert_v or_o charm_v therewith_o that_o he_o do_v not_o attend_v to_o the_o business_n of_o sensation_n this_o be_v one_o reason_n why_o such_o as_o be_v far_o go_v in_o drink_n have_v none_o of_o their_o sense_n aright_o but_o as_o to_o the_o illustration_n of_o this_o matter_n you_o may_v expect_v more_o hereafter_o note_v that_o the_o sensitive_a soul_n be_v the_o only_a thing_n iâ—_n a_o animal_n that_o have_v perception_n and_o therefore_o the_o only_a thing_n that_o be_v sensible_a of_o any_o grievance_n weariness_n hunger_n pleasure_n comfort_n etc._n etc._n second_o it_o be_v requisite_a that_o it_o shall_v use_v all_o mean_n that_o be_v in_o its_o power_n that_o the_o impression_n shall_v be_v bring_v to_o it_o very_o entire_o exact_o smart_o etc._n etc._n so_o as_o to_o have_v due_a notice_n of_o all_o object_n and_o the_o small_a impression_n that_o may_v be_v for_o which_o good_a end_n and_o purpose_v god_n have_v endue_v the_o sensitive_a soul_n as_o will_v be_v full_o prove_v with_o a_o power_n of_o contract_v all_o the_o sensile_n small_a and_o slender_a pipe_n vessel_n or_o passage_n of_o the_o animal_n spirit_n for_o the_o more_o express_a distinct_a and_o accurate_a conveyance_n of_o all_o impression_n by_o the_o help_n of_o compression_n therefore_o the_o sensitive_a soul_n take_v the_o advantage_n thereof_o for_o better_a information_n in_o order_n to_o self-preservation_n do_v by_o the_o appointment_n of_o the_o preserver_n of_o all_o thing_n execute_v his_o power_n by_o the_o aforementioned_a vigilative_a contraction_n of_o those_o part_n to_o cause_v their_o tension_n and_o great_a compression_n of_o the_o animal_n spirit_n to_o improve_v the_o impression_n that_o be_v to_o be_v convey_v to_o he_o and_o render_v they_o more_o observable_a this_o god_n who_o have_v make_v nothing_o to_o be_v idle_a and_o particular_o order_v the_o sensitive_a soul_n in_o adam_n for_o labour_n especeal_o in_o reference_n to_o their_o own_o safety_n and_o preservation_n have_v make_v to_o be_v the_o ordinary_a employ_v or_o day-work_a of_o the_o sensitive_a soul_n that_o by_o the_o say_v vigilative_a contraction_n the_o organ_n membrane_n vessel_n etc._n etc._n may_v be_v render_v more_o tense_n and_o firm_a and_o the_o animal_n spirit_n more_o compress_v springy_a prompt_a flippant_a and_o forcible_a for_o the_o benefit_n of_o sense_n and_o motion_n upon_o all_o occasion_n of_o defence_n flight_n struggle_v etc._n etc._n which_o be_v our_o state_n of_o vigilancy_n as_o have_v be_v intimate_v but_o the_o keep_n of_o the_o say_a part_n membrane_n etc._n etc._n in_o continual_a contraction_n even_o against_o the_o renitency_n of_o the_o elastic_a spirit_n which_o resist_v and_o thrust_v the_o hard_a against_o their_o vessel_n by_o how_o much_o the_o more_o they_o compress_v they_o by_o the_o vigilative_a contraction_n be_v a_o continual_a tedious_a labour_n and_o fatigue_n of_o which_o the_o sensitive_a soul_n be_v sensible_a as_o the_o only_a perceiver_n of_o lassitude_n or_o indeed_o of_o any_o thing_n beside_o in_o a_o animal_n and_o in_o his_o nature_n but_o material_a changeable_a fatigable_a frail_a subject_a to_o be_v wear_v out_o and_o capable_a of_o decay_n which_o make_v the_o certainty_n of_o death_n in_o all_o animal_n and_o in_o we_o since_o the_o fall_n into_o a_o animal_n nature_n do_v upon_o that_o account_n and_o lest_o the_o continual_a contraction_n and_o tensive_a stress_n of_o part_n by_o that_o mean_n shall_v spoil_v their_o tone_n and_o to_o recruit_v the_o waste_a spirit_n by_o rest_n after_o tuggingall_a day_n at_o the_o vigilative_a contraction_n grow_v willing_a to_o give_v over_o the_o drudgery_n however_o convenient_a for_o the_o use_v aforesaid_a therefore_o be_v allow_v convenient_a rest_n by_o his_o maker_n he_o for_o the_o great_a benefit_n of_o refection_n without_o which_o he_o can_v continue_v his_o be_v and_o for_o the_o sweetness_n of_o ease_n loosen_v the_o reins_o of_o vigilative_a contraction_n whereupon_o sensation_n and_o promptitude_n to_o motion_n which_o be_v maintain_v by_o that_o contraction_n cause_v the_o tension_n of_o organ_n and_o compression_n of_o the_o animal_n spirit_n as_o have_v be_v mechanical_o demonstrate_v fail_v by_o the_o relaxation_n of_o those_o organ_n membrane_n and_o vessel_n of_o the_o spirit_n and_o the_o consequent_a expansion_n of_o the_o animal_n spirit_n so_o that_o now_o only_a the_o compression_n of_o the_o atmosphere_n remain_v which_o as_o you_o see_v in_o a_o gut_n half_n full_a of_o air_n under_o that_o pressure_n be_v not_o sufficient_a to_o convey_v the_o impression_n with_o any_o smartness_n or_o cause_v the_o animal_n spirit_n to_o spring_v vigorous_o into_o motion_n which_o decay_n or_o failure_n of_o sense_n and_o motion_n by_o relaxation_n and_o the_o consequent_a expansion_n of_o the_o animal_n spirit_n be_v the_o state_n of_o natural_a sleep_n note_v that_o relaxation_n be_v a_o necessary_a consequence_n of_o the_o privation_n of_o contraction_n and_o require_v no_o labour_n but_o a_o bare_a remission_n of_o that_o contraction_n note_v that_o the_o watch_a part_n of_o our_o life_n be_v uphold_v by_o force_n and_o that_o nullum_fw-la violentum_fw-la est_fw-la diuturnum_fw-la and_o consequent_o a_o necessity_n of_o sleep_n and_o at_o last_o of_o death_n itself_o thus_o have_v you_o the_o true_a reason_n of_o sleep_v and_o watch_v which_o will_v natural_o plain_o and_o easy_o solve_v all_o the_o phenomena_n thereof_o for_o it_o be_v most_o evident_a from_o the_o premise_n 1._o why_o watch_v and_o sleep_v observe_v a_o proportion_n between_o they_o the_o be_v tire_v with_o one_o be_v the_o cause_n of_o the_o other_o 2._o why_o sense_n and_o motion_n do_v fail_v so_o much_o in_o sleep_n viz._n by_o the_o relaxation_n of_o all_o part_n and_o expansion_n of_o the_o animal_n spirit_n 3._o why_o they_o always_o fail_v together_o and_o in_o like_a proportion_n 4._o why_o they_o do_v not_o whole_o fail_v in_o sleep_n because_o the_o compressure_n of_o the_o atmosphere_n etc._n etc._n remain_v 5._o why_o in_o sleep_v the_o limb_n be_v like_o a_o gut_n half_n full_a of_o air_n lax_n limber_a flaccid_a and_o yield_v all_o manner_n of_o way_n because_o all_o the_o innumerable_a small_a vessel_n that_o contain_v the_o elastic_a animal_n spirit_n be_v as_o that_o half_a fill_v gut_n i_o mention_v not_o tight_o fill_v which_o if_o they_o be_v will_v be_v firm_a and_o tense_n as_o such_o a_o gut_n blow_v up_o very_o full_a and_o forcible_o be_v which_o vessel_n be_v all_o over_o the_o body_n confirm_v the_o whole_a tone_n when_o we_o be_v awake_a and_o the_o vigilative_a contraction_n compress_n the_o animal_n spirit_n into_o a_o steadiness_n and_o as_o it_o be_v a_o kind_a of_o solidity_n 6._o why_o as_o appear_v by_o statick_a demonstration_n and_o experiment_n we_o perspire_v more_o when_o asleep_a than_o awake_a because_o the_o pore_n be_v close_v by_o the_o vigilative_a contraction_n and_o open_v in_o sleep_n by_o the_o contrary_a relaxation_n which_o therefore_o always_o cause_v free_a perspiration_n where_o ever_o it_o happen_v as_o in_o faint_a fit_n syncopes_fw-la leipothymy_n and_o by_o warmth_n especial_o if_o moist_a and_o emollient_a as_o in_o bath_n fomentation_n foot_n wash_v head_n wash_v etc._n etc._n as_o also_o when_o pleasure_n relax_n as_o in_o the_o act_n of_o venery_n great_a joy_n after_o good_a meal_n or_o some_o glass_n of_o wine_n etc._n etc._n all_o which_o cause_n plentiful_a perspiration_n because_o they_o relax_v and_o thereby_o open_a the_o pore_n as_o more_o full_o appear_v in_o the_o follow_a discourse_n by_o reason_n of_o the_o pleasure_n that_o they_o cause_n which_o divert_v the_o sensitive_a soul_n from_o his_o employ_v of_o contraction_n 7._o why_o the_o pore_n be_v open_a by_o the_o relaxation_n we_o sweat_v in_o our_o sleep_n if_o we_o be_v fill_v with_o matter_n for_o it_o viz._n 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o be_v much_o sweat_v in_o sleep_n argue_v that_o much_o food_n or_o nutriment_n be_v take_v of_o which_o drink_n be_v the_o great_a part_n in_o bulk_n even_o in_o sober_a person_n i_o mention_v this_o to_o show_v the_o difference_n in_o the_o case_n of_o perspiration_n and_o sweat_v for_o that_o always_o happen_v in_o sleep_n but_o not_o sweat_v unless_o
sensation_n of_o the_o sensile_a part_n which_o can_v well_o happen_v in_o that_o sound_a sleep_n wherein_o there_o be_v so_o little_a feel_v by_o reason_n of_o the_o say_a relaxation_n and_o because_o relaxation_n oppose_v contraction_n by_o which_o that_o shiver_a be_v promote_v such_o a_o relaxation_n and_o failure_n of_o feel_v thereupon_o be_v the_o true_a cause_n why_o opium_n put_v off_o ague_n fit_n etc._n etc._n so_o 20._o the_o relaxation_n in_o sleep_n stop_v vomit_v by_o take_v away_o the_o sense_n of_o the_o irritate_v cause_n and_o quiet_v as_o i_o have_v intimate_v all_o motion_n in_o general_a so_o sleep_v stop_n hiccough_n hemorrhage_n diary_n fever_n etc._n etc._n 21._o why_o watch_v labour_n or_o what_o impair_v the_o spirit_n and_o tire_v the_o sensitive_a soul_n incline_v we_o to_o sleep_v that_o be_v dispose_v the_o sensitive_a soul_n the_o only_a feeler_n of_o lassitude_n to_o give_v over_o contract_n the_o sensile_a part_n which_o as_o will_v plain_o appear_v by_o and_o by_o spend_v the_o spirit_n as_o sleep_v by_o relax_v they_o cause_v a_o recruit_v thereof_o to_o be_v short_a though_o one_o can_v hardly_o be_v too_o long_o in_o solve_v phenomena_n which_o be_v the_o proof_n of_o the_o truth_n of_o a_o man_n assertion_n the_o mechanical_a demonstration_n that_o i_o have_v make_v of_o the_o state_n of_o sleep_v and_o wake_v do_v so_o evident_o explicate_v all_o the_o phenomena_n of_o both_o that_o i_o be_o even_o ashamed_a to_o run_v any_o far_o upon_o such_o plain_a matter_n so_o obvious_a be_v thing_n when_o the_o truth_n be_v know_v and_o therefore_o have_v mention_v those_o circumstance_n and_o effect_n of_o sleep_n that_o main_o concern_v we_o i_o must_v give_v over_o lest_o the_o world_n shall_v think_v that_o i_o take_v all_o my_o reader_n to_o be_v idiot_n by_o use_v too_o many_o word_n in_o so_o obvious_a a_o thing_n or_o that_o i_o be_o no_o better_o for_o use_v they_o without_o cause_n for_o the_o truth_n of_o this_o matter_n seem_v to_o i_o to_o outshine_v all_o the_o argument_n i_o can_v make_v for_o it_o such_o splendour_n do_v truth_n show_v upon_o the_o first_o glimpse_n thereof_o as_o i_o take_v the_o account_n i_o give_v of_o sleep_n and_o watch_v to_o be_v for_o the_o opinion_n i_o have_v meet_v concern_v they_o be_v quite_o contrary_a to_o or_o very_o remote_a from_o what_o i_o have_v state_v 1._o they_o go_v quite_o contrary_a to_o it_o that_o say_v that_o the_o animal_n spirit_n be_v expanded_a and_o the_o pore_n of_o the_o brain_n etc._n etc._n more_o open_a and_o consequent_o more_o lax_n in_o watch_v as_o willis_n and_o several_a other_o who_o therefore_o say_v that_o coffee_n volatile_a salt_n etc._n etc._n be_v antihypnotick_n or_o good_a against_o too_o much_o sleepiness_n because_o they_o cause_v a_o expansion_n of_o the_o spirit_n and_o open_v the_o pore_n of_o the_o brain_n suppose_v forsooth_o that_o they_o march_v up_o and_o down_o and_o so_o keep_v the_o great_a stir_n upon_o the_o false_a imagination_n of_o their_o road_n be_v more_o open_a which_o as_o be_v prove_v be_v real_o more_o close_a coffee_n keep_v we_o from_o sleep_n by_o dry_v bind_a and_o both_o way_n constr_v the_o vessel_n as_o also_o by_o a_o wide_a grate_a quality_n which_o therefore_o do_v irritate_fw-la they_o to_o contract_v beside_o that_o the_o saline_n particle_n cause_v a_o agitation_n may_v contribute_v thereto_o so_o that_o by_o constr_v and_o agitate_v it_o direct_o oppose_v sleep_n which_o proceed_v from_o relaxation_n and_o quietness_n 2._o they_o be_v very_o remote_a from_o the_o mark_n that_o say_v as_o wedeliâ—s_a assert_n all_o do_v that_o vapour_n be_v the_o cause_n of_o natural_a sleep_n which_o bear_v no_o manner_n of_o proportion_n thereto_o as_o be_v show_v as_o they_o be_v also_o who_o mâ—dly_o talk_v that_o the_o animal_n spirit_n which_o have_v neither_o life_n sense_n motion_n or_o election_n do_v of_o themselves_o retire_v very_o know_o to_o the_o brain_n in_o sâ—eep_n and_o leave_v the_o limb_n etc._n etc._n destitute_a of_o they_o whereas_o as_o have_v be_v mechanical_o prove_v they_o have_v more_o room_n than_o that_o at_o other_o time_n in_o 〈◊〉_d limb_n and_o all_o the_o sensile_a part_n but_o i_o will_v not_o argue_v against_o such_o senseless_a and_o precarious_a absurdity_n it_o be_v not_o worth_a the_o while_n especial_o since_o the_o truth_n be_v manifest_o discover_v it_o will_v not_o have_v be_v so_o silly_a to_o have_v affirm_v the_o quite_o contrary_a viz._n that_o the_o animal_n spirit_n be_v force_v into_o the_o soft_a and_o yield_a brain_n in_o watch_v by_o the_o vigilative_a contraction_n of_o all_o the_o senfile_v part_n repel_v they_o as_o when_o cold_a repel_v they_o by_o a_o strong_a contraction_n of_o the_o part_n and_o cause_v a_o stupor_n or_o sleep_n thereof_o as_o they_o call_v it_o but_o what_o have_v we_o to_o do_v with_o such_o insufferable_a trash_n therefore_o bid_v it_o adieu_n let_v we_o pursue_v our_o business_n that_o it_o be_v the_o sensitive_a soul_n and_o nothing_o but_o it_o have_v that_o contract_n power_n be_v evident_a 1._o because_o it_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n as_o such_o and_o that_o nothing_o beside_o it_o have_v any_o life_n perception_n motion_n or_o power_n and_o therefore_o must_v rest_v till_o they_o be_v move_v 2._o because_o that_o when_o the_o sensitive_a soul_n be_v divert_v by_o intense_a pleasure_n from_o attend_v his_o business_n immediate_o relaxation_n follow_v as_o in_o the_o pleasure_n of_o the_o act_n of_o venery_n by_o wine_n joy_n etc._n etc._n in_o which_o you_o have_v all_o the_o effect_n of_o relaxation_n as_o deadness_n of_o the_o eye_n dilatation_n of_o the_o pupilla_fw-la plentiful_a perspiration_n floridity_n of_o the_o skin_n a_o large_a pulse_n and_o sometime_o a_o considerable_a failure_n of_o sense_n and_o motion_n as_o in_o the_o most_o pleasant_a time_n of_o the_o venereal_a act_n deliquiums_n drunkenness_n syncopes_fw-la or_o ecstasy_n upon_o intense_a pleasure_n which_o be_v very_o proper_o call_v ecstasy_n leipothymy_n leipopsychy_n etc._n etc._n which_o signify_v the_o soul_n leave_v we_o without_o his_o help_n by_o contraction_n which_o he_o then_o do_v not_o exercise_n as_o be_v charm_v and_o whole_o take_v up_o with_o pleasure_n this_o be_v the_o true_a cause_n of_o all_o deliquium_n etc._n etc._n upon_o pleasure_n joy_n etc._n etc._n all_o which_o cause_n great_a relaxation_n and_o thereby_o loss_n of_o sense_n and_o motion_n as_o be_v its_o necessary_a consequence_n 3._o because_o grievous_a sensation_n which_o belong_v only_o to_o the_o sensitive_a soul_n put_v we_o immediate_o out_o of_o sleep_n into_o a_o vigilative_a contraction_n 4._o because_o the_o sensitive_a soul_n can_v when_o we_o be_v sleepy_a oppose_v it_o by_o continue_v the_o vigilative_a contraction_n which_o prove_v vigilative_a contraction_n to_o be_v in_o his_o power_n note_v that_o there_o be_v also_o other_o sort_n of_o leipothymy_n deliquium_n etc._n etc._n upon_o the_o sensitive_a soul_n be_v overtired_n whereof_o natural_a sleep_n be_v but_o a_o common_a and_o ordinary_a degree_n that_o happen_v of_o course_n for_o our_o relief_n or_o overbear_v with_o some_o fatigue_n etc._n etc._n as_o when_o somewhat_o grieve_v at_o stomach_n and_o that_o it_o have_v lay_v about_o it_o all_o manner_n of_o way_n by_o vomit_v convulsive_a motion_n etc._n etc._n to_o be_v rid_v of_o it_o till_o it_o can_v work_v no_o long_o whereupon_o it_o lay_v down_o the_o cudgel_n desi_v from_o all_o further_a endeavour_n by_o contraction_n yield_v itself_o to_o ease_n see_v all_o strive_v be_v to_o no_o effect_n so_o that_o though_o this_o deliquium_fw-la and_o the_o former_a differ_v in_o their_o first_o cause_n yet_o do_v they_o agree_v in_o the_o last_o and_o immediate_a viz._n the_o sensitive_a soul_n be_v not_o attend_v his_o business_n of_o contraction_n whereupon_o follow_v a_o mighty_a relaxation_n as_o appear_v by_o the_o deadness_n or_o relaxation_n of_o the_o cornea_n dilatation_n of_o the_o pupil_n a_o great_a laxity_n of_o all_o part_n a_o large_a pulse_n or_o none_o very_o plentiful_a perspiration_n stop_v of_o hemorrhage_n and_o all_o flux_n that_o require_v contraction_n etc._n etc._n which_o happen_v both_o upon_o the_o account_n of_o the_o great_a relaxation_n itself_o as_o have_v be_v show_v and_o the_o almost_o absolute_a rest_n of_o all_o thing_n by_o the_o sensitive_a soul_n withdraw_a himself_n from_o business_n more_o than_o in_o sleep_n itself_o i_o therefore_o observe_v the_o degree_n of_o sleep_n etc._n etc._n do_v note_n that_o god_n and_o nature_n use_v a_o due_a proportion_n in_o all_o thing_n the_o sensitive_a soul_n use_v several_a degree_n of_o relaxation_n according_a as_o he_o be_v tire_v and_o refection_n be_v want_v hence_o it_o be_v that_o such_o as_o be_v much_o tire_v sleep_n more_o profound_o that_o our_o first_o
which_o argue_v that_o the_o specific_a combination_n of_o the_o oily_a and_o volatile_a part_n baffle_v all_o coction_n digestion_n circulation_n and_o percolation_n that_o have_v happen_v in_o the_o body_n dioscorides_n and_o aeginela_fw-la speak_v of_o opium_n say_v 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d that_o be_v the_o smell_n of_o the_o medicament_n be_v expanded_a over_o the_o whole_a body_n which_o thing_n of_o its_o nature_n do_v as_o garlic_n onion_n semen_n animale_a which_o cause_v rankness_n all_o over_o male_a creature_n as_o ram_n boar_n bull_n etc._n etc._n 14._o le_fw-fr febure_n in_o his_o chemistry_n part_v 2._o p._n 33_o say_v that_o opium_n have_v a_o volatile_a salt_n inseparable_o mix_v with_o sulphur_n or_o oily_a part_n 15._o wedelius_n in_o his_o opiologia_fw-la lib._n 2._o sect._n 1_o cap._n 4._o p._n 91._o speak_v of_o opium_n say_v sal_fw-la ejus_fw-la cum_fw-la sulphur_n intime_fw-la combinatum_fw-la sudores_fw-la efficit_fw-la that_o be_v its_o salt_n be_v intimate_o combine_v with_o sulphur_n or_o oil_n cause_v sweat_n and_o lib._n 2._o p._n 143._o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d obtinuit_fw-la non_fw-la facile_fw-la dissipabilem_fw-la that_o be_v it_o have_v a_o contexture_n not_o easy_o dissipable_a 18._o all_o know_v how_o apt_a volatile_a salt_n and_o oily_a part_n be_v to_o combine_v therefore_o opium_n act_n and_o produce_v its_o usual_a good_a effect_n by_o a_o sal-volatile-oleosum_a somewhat_o more_o active_a than_o that_o in_o our_o membrane_n who_o principle_n be_v most_o intimate_o and_o strict_o combine_v and_o so_o that_o it_o be_v qualify_v in_o the_o high_a degree_n for_o our_o purpose_n because_o 1._o it_o agree_v in_o principle_n with_o our_o membrane_n 2._o that_o its_o sal-volatile-oleosum_a be_v more_o active_a and_o vigorous_a than_o that_o of_o the_o membrane_n to_o actuate_v and_o excite_v the_o spiritus_fw-la insiti_fw-la and_o fine_o to_o tickle_v and_o gratify_v the_o membrane_n 3._o that_o the_o volatile_a salt_n and_o oily_a part_n be_v so_o intimate_o combine_v do_v delicious_o qualify_v one_o the_o other_o for_o that_o purpose_n while_o the_o oily_a smooth_v and_o lenify_v the_o volatile_a salt_n and_o the_o volatile_a salt_n actuate_v and_o quicken_v the_o oily_a and_o that_o be_v so_o combine_v 4._o both_o conspire_v to_o a_o permanent_a and_o exalt_a pleasure_n of_o the_o membrane_n especial_o at_o stomach_n and_o the_o venereal_a part_n where_o they_o be_v so_o exquisite_o dispose_v for_o sensation_n therefore_o the_o sal-volatile-oleosum_a of_o opium_n separate_v from_o its_o rosin_n be_v most_o consummate_a and_o best_a qualify_v that_o possible_o can_v be_v imagine_v to_o please_v gratify_v and_o fine_o to_o titillate_v our_o membrane_n or_o organ_n of_o sensation_n which_o be_v the_o thing_n require_v i_o can_v better_o illustrate_v its_o nature_n than_o by_o the_o most_o exalt_a thing_n in_o a_o animal_n viz._n it_o be_v semen_n therefore_o for_o confirmation_n of_o its_o principle_n and_o excellency_n therein_o i_o will_v consider_v its_o likeness_n and_o agreement_n therewith_o 1._o in_o be_v both_o a_o shall_v volatile-oleosum_a 2._o in_o have_v a_o more_o active_a vigorous_a and_o exalt_v sal-volatile-oleosum_a than_o any_o part_n of_o the_o animal_n 3._o in_o have_v the_o volatile_a salt_n and_o oleous_a particle_n intimate_o combine_v for_o semen_n animale_a will_v as_o opium_n keep_v very_o long_o uncorrupted_a as_o appear_v by_o its_o long_a stay_n in_o the_o vesiculae_fw-la seminales_fw-la of_o some_o animal_n that_o do_v not_o excern_v it_o in_o many_o year_n 4._o in_o that_o both_o be_v apt_a to_o mix_v with_o all_o fort_n of_o menstruum_n and_o both_o mole_n minimum_n virtute_fw-la maxima_fw-la 5._o in_o have_v much_o the_o same_o smell_n viz._n a_o rank_n and_o vehement_a one_o 6._o in_o taint_v the_o body_n therewith_o as_o have_v be_v show_v 7._o in_o be_v much_o of_o the_o same_o weight_n as_o appear_v by_o both_o sink_n in_o water_n etc._n etc._n 8._o the_o taste_n must_v in_o all_o probability_n have_v a_o rankness_n in_o it_o like_o that_o of_o opium_n because_o it_o give_v a_o rank_a taste_n to_o the_o whole_a body_n of_o male_a creature_n 9_o both_o excite_v venery_n cause_n erection_n venereal_a fury_n and_o nocturnal_a pollution_n etc._n etc._n 10._o both_o cause_n boldness_n courage_n and_o magnanimity_n which_o be_v reckon_v among_o the_o effect_n of_o opium_n and_o be_v the_o common_a effect_n of_o plenitude_n of_o seed_n in_o animal_n that_o be_v otherwise_o pusillanimous_a in_o time_n of_o copulation_n so_o modest_a and_o sheepish_a boy_n grow_v much_o more_o assure_v â—old_a and_o as_o they_o common_o call_v it_o manlike_a upon_o puberty_n and_o girl_n grow_v more_o womanlike_a in_o their_o disposition_n and_o it_o be_v my_o observation_n that_o the_o man_n who_o breed_v most_o of_o the_o sem._n virile_a be_v general_o if_o not_o always_o the_o most_o valiant_a 11._o both_o do_v cause_n a_o great_a relaxation_n upon_o the_o pleasure_n thereof_o as_o appear_v after_o a_o good_a do_v of_o opium_n and_o upon_o emission_n of_o the_o other_o by_o the_o deadness_n of_o the_o eye_n or_o laxity_n of_o the_o cornea_n in_o both_o case_n dilatation_n of_o the_o pupil_n floridity_n of_o the_o skin_n large_a perspiration_n laxity_n of_o the_o limb_n sleepiness_n loss_n of_o memory_n and_o sense_n alienation_n of_o the_o mind_n a_o wide_a pulse_n indolence_n loss_n of_o feel_v in_o both_o case_n and_o other_o sign_n of_o relaxation_n 12._o both_o opium_n and_o puberty_n cause_v a_o growth_n of_o the_o penis_n breast_n and_o increase_v milk_n by_o reason_n of_o the_o relaxation_n that_o they_o cause_n which_o as_o in_o sleep_n cause_v the_o great_a nutrition_n but_o of_o the_o manner_n how_o it_o happen_v upon_o relaxation_n more_o hereafter_o if_o there_o be_v occasion_n hence_o it_o be_v 13._o that_o both_o opium_n and_o puberty_n be_v apt_a to_o bring_v down_o the_o menses_fw-la and_o open_v the_o viae_fw-la by_o the_o relaxation_n and_o that_o marriage_n or_o the_o pleasure_n of_o venereal_a act_n do_v by_o the_o like_a relaxation_n promote_v the_o menses_fw-la that_o both_o opium_n and_o such_o act_n be_v apt_a to_o cause_n miscarriage_n by_o relax_v the_o neck_n of_o the_o womb_n etc._n etc._n 14._o both_o cause_n sadness_n and_o dejection_n when_o the_o operation_n be_v over_o as_o indeed_o pleasure_n general_o do_v especial_o if_o intense_a 15._o both_o opium_n and_o sem._n animale_a prevent_v lassitude_n and_o cause_n euphory_n or_o easy_a undergo_n of_o labour_n hence_o it_o be_v that_o stone_n horse_n will_v not_o be_v so_o soon_o tire_v when_o full_a thereof_o and_o quick_o recover_v if_o tire_a which_o may_v doubtless_o be_v observe_v in_o other_o animal_n but_o that_o they_o be_v not_o use_v to_o labour_n and_o so_o not_o obvious_a to_o be_v observe_v 16._o author_n do_v say_v that_o sem._n virile_a take_v of_o venereal_a impotence_n procure_v love_n etc._n etc._n which_o doubtless_o must_v be_v by_o exciting_a to_o venery_n as_o opium_n do_v thus_o the_o genitals_o of_o buck_n boar_n buck_n of_o hare_n cock_n etc._n etc._n do_v as_o opium_n excite_v venery_n and_o the_o seed_n of_o animal_n as_o of_o a_o camel_n and_o the_o aforesaid_a creature_n come_v to_o be_v esteem_v hypnotick_n and_o doubtless_o all_o animal_n seed_n especial_o of_o the_o more_o salaceous_a creature_n be_v a_o opiate_n in_o some_o degree_n to_o be_v short_a the_o main_a if_o not_o all_o the_o difference_n in_o their_o effect_n arise_v only_o 1._o from_o the_o different_a part_n that_o they_o affect_v because_o opium_n affect_v the_o stomach_n the_o venereal_a and_o all_o the_o membrane_n in_o general_a and_o sem._n animale_a only_a the_o venereal_a part_n immediate_o though_o a_o intense_a pleasure_n of_o one_o part_n do_v affect_v the_o whole_a 2._o that_o opium_n do_v affect_v with_o a_o sense_n of_o pleasure_n more_o permanent_a viz._n for_o many_o hour_n as_o have_v be_v say_v and_o that_o the_o pleasure_n of_o the_o other_o be_v momentary_a therefore_o opium_n act_n by_o cause_v a_o intense_a permanent_a and_o charm_a pleasure_n of_o the_o membrane_n in_o general_a but_o more_o particular_o of_o the_o stomach_n and_o venereal_a part_n as_o be_v more_o exquisite_o dispose_v for_o sensation_n for_o the_o preservation_n of_o the_o individuum_fw-la and_o species_n it_o can_v be_v much_o wonder_v at_o consider_v our_o active_a principle_n be_v a_o sal-volatile-oleosum_a and_o that_o opium_n be_v such_o and_o that_o we_o natural_o carry_v a_o opiate_n within_o we_o that_o in_o some_o case_n our_o ordinary_a sal-volatile-oleosum_a or_o that_o of_o the_o choler_n semen_n etc._n etc._n be_v by_o some_o accident_n exalt_v towards_o the_o nature_n of_o opium_n may_v have_v the_o effect_v of_o a_o opiate_n upon_o we_o by_o cause_v sopor_n and_o lethargic_a distemper_n fuâ—or_fw-la uterinus_fw-la by_o titillation_n etc._n etc._n thus_o the_o spume_n of_o some_o male_a animal_n mummy_n etc._n etc._n
be_v repute_v opiate_n borellus_n speak_v of_o a_o soporiferous_a aura_n that_o proceed_v from_o one_o thumb_n cure_v by_o a_o caustick_a i_o have_v read_v of_o a_o cataphora_fw-it from_o worm_n a_o soporiferous_a fume_v from_o the_o womb_n and_o very_o many_o such_o sort_n of_o instance_n which_o thing_n be_v now_o easy_o conceive_v for_o it_o be_v but_o suppose_v a_o fume_v of_o the_o nature_n of_o sem._n animale_a or_o its_o aura_n for_o i_o can_v no_o long_o doubt_v but_o it_o be_v a_o opiate_n and_o it_o will_v have_v much_o the_o same_o effect_n with_o opium_n if_o it_o be_v fit_a to_o use_v it_o after_o the_o same_o manner_n have_v show_v 1._o which_o be_v the_o predominant_a active_a principle_n in_o opium_n and_o how_o combine_v etc._n etc._n 2._o which_o of_o they_o produce_v the_o usual_a and_o laudable_a effect_n of_o opium_n and_o why_o in_o general_a i_o come_v now_o to_o the_o three_o particular_a viz._n to_o show_v iii_o which_o of_o they_o produce_v its_o ill_a effect_n and_o why_o it_o be_v ill_a effect_n be_v these_o viz._n nauseas_fw-la vomit_n which_o be_v general_o very_o dismal_a with_o great_a distress_n and_o sometime_o dangerous_a swim_v in_o the_o head_n hiccough_n distress_n anxiety_n convulsion_n faint_n leipothymy_n syncopes_fw-la etc._n etc._n 1._o note_v that_o its_o grievous_a effect_n be_v at_o or_o about_o the_o region_n of_o the_o stomach_n or_o particular_o the_o mouth_n or_o pit_n thereof_o or_o thence_o arise_v by_o consent_n 2._o note_v that_o see_v there_o be_v nothing_o so_o good_a but_o may_v cause_v evil_a effect_n in_o a_o excessive_a quantity_n this_o enquiry_n be_v more_o proper_o what_o principle_n or_o principle_n of_o opium_n do_v cause_n those_o ill_a effect_n in_o a_o ordinary_a do_v for_o what_o will_v in_o a_o moderate_a do_v will_v be_v sure_a cause_v they_o in_o a_o excessive_a do_v 3._o note_v that_o all_o the_o constant_a effect_n of_o opium_n as_o you_o may_v observe_v in_o the_o enumeration_n thereof_o in_o the_o four_o chapter_n be_v good_a and_o laudable_a effect_n it_o follow_v therefore_o that_o the_o bad_a be_v accidental_a 1._o it_o be_v not_o the_o earthy_a or_o phlegmatic_a part_n of_o opium_n that_o cause_v those_o ill_a effect_n because_o they_o be_v passive_a principle_n and_o consequent_o have_v not_o such_o a_o power_n beside_o that_o they_o be_v know_v to_o be_v innocent_a 2._o opium_n have_v all_o those_o ill_a effect_n when_o both_o the_o earthy_a and_o phlegmatic_a part_n be_v separate_v from_o it_o as_o when_o a_o extract_v of_o well_o torrefy_v opium_n be_v make_v in_o spirit_n of_o wine_n for_o by_o that_o mean_v the_o phlegmatic_a part_n be_v dry_v up_o and_o the_o earthy_a part_n subside_o and_o be_v separate_v yea_o such_o extract_v make_v by_o spirit_n of_o wine_n do_v cause_n those_o evil_a effect_n rather_o more_o than_o crude_a opium_n with_o its_o earth_n and_o phlegm_n in_o it_o as_o experience_n assure_v we_o and_o reason_n will_v plain_o confirm_v by_o and_o by_o however_o fond_a the_o world_n be_v of_o such_o preparation_n 3._o it_o be_v evident_a from_o the_o premise_n that_o the_o sal-volatile-oleosum_a of_o opium_n can_v cause_v those_o vomit_n hiccough_n etc._n etc._n for_o they_o be_v the_o effect_n of_o grievous_a sensation_n at_o stomach_n but_o the_o sal-volatile-oleosum_a cause_n a_o most_o agreeable_a and_o please_a sensation_n at_o stomach_n 4._o nothing_o quiet_v vomit_n convulsion_n â—coughs_n etc._n etc._n more_o than_o that_o sal-volatile-oleosum_a of_o opium_n 5._o experience_n inform_v we_o that_o the_o sal-volatile-oleosum_a of_o opium_n separate_v from_o all_o other_o part_n and_o principle_n thereof_o never_o cause_v such_o evil_a effect_n as_o i_o and_o another_o physician_n in_o london_n can_v testify_v as_o do_v also_o le_fw-fr mort_fw-fr in_o the_o most_o learned_a dr._n love_n collectanea_fw-la where_o he_o say_v of_o such_o a_o preparation_n thereof_o as_o contain_v only_o the_o sal-volatile-oleosum_a that_o nunquam_fw-la anxietates_fw-la circa_fw-la praecordia_fw-la aut_fw-la phantasias_fw-la conciliat_fw-la that_o be_v it_o never_o cause_v anxiety_n about_o the_o mouth_n of_o the_o stomach_n etc._n etc._n for_o that_o be_v most_o proper_o to_o be_v understand_v by_o praecordia_fw-la wedelius_n testify_v the_o like_a of_o such_o another_o preparation_n and_o so_o do_v several_a author_n though_o they_o do_v not_o in_o the_o least_o know_v why_o but_o only_o by_o experience_n 6._o it_o be_v fix_v salt_n be_v innocent_a in_o its_o nature_n and_o but_o the_o 32d_o part_n of_o opium_n which_o be_v too_o inconsiderable_a in_o a_o ordinary_a moderate_a do_v to_o cause_v any_o sensible_a effect_n it_o follow_v therefore_o that_o be_v must_v be_v the_o resinous_n part_n of_o opium_n which_o it_o have_v in_o a_o considerable_a quantity_n that_o must_v cause_v those_o ill_a effect_n this_o manifest_o appear_v 1._o because_o a_o tincture_n of_o opiam_fw-la in_o water_n which_o take_v up_o none_o of_o the_o rosin_n but_o let_v it_o fall_v into_o the_o bottom_n never_o cause_v any_o such_o ill_a effect_n which_o it_o do_v not_o also_o if_o reduce_v to_o a_o extract_v by_o evaporation_n yet_o have_v they_o all_o the_o usual_a good_a effect_n of_o opium_n 2._o wedelius_n in_o his_o opiolog_n assure_v the_o same_o of_o the_o like_a preparation_n in_o phlegm_n of_o distil_a vinegar_n l._n 2._o sect._n 1_o c._n 5._o p._n 92._o 3._o a_o extract_v of_o opium_n in_o spirit_n of_o wine_n do_v often_o cause_v those_o ill_a effect_n and_o no_o other_o preparation_n cause_v they_o as_o often_o wedelius_n ibid._n a_o laudano_n opiato_fw-it cum_fw-la spiritu_fw-la vini_n correcto_fw-la solum_fw-la ferâ—_n observavimus_fw-la ortos_fw-la vomitus_fw-la a_o nostro_fw-la vero_fw-la quod_fw-la cum_fw-la phlegmate_fw-it aceti_fw-la distillati_fw-la fieri_fw-la diximus_fw-la nunquam_fw-la vomitum_fw-la vel_fw-la nauseam_fw-la saltem_fw-la contigisse_fw-la meminimus_fw-la that_o be_v we_o have_v observe_v vomit_n almost_o only_o from_o laudanum_n prepare_v with_o spirit_n of_o wine_n but_o never_o any_o vomit_v or_o nausea_n from_o that_o prepare_v in_o phlegm_n of_o distil_a vinegar_n which_o he_o confirm_v l._n 1._o sect_n 2._o c._n 4._o p._n 62._o saying_n in_o latin_a that_o a_o curious_a observation_n be_v to_o be_v note_v by_o which_o it_o appear_v that_o a_o extract_v of_o opium_n with_o spirit_n of_o wine_n show_v more_o narcotick_a force_n by_o which_o he_o mean_v that_o it_o cause_v more_o ill_a effect_n than_o prepare_v in_o distil_a vinegar_n whereas_o that_o in_o spirit_n of_o wine_n have_v nothing_o more_o in_o it_o than_o that_o in_o vinegar_n beside_o the_o râ—sinous_n part_n therefore_o these_o do_v cause_n all_o the_o mischief_n note_v also_o that_o a_o extract_v in_o spirit_n of_o wine_n have_v in_o it_o quantity_n for_o quantity_n more_o of_o the_o râ—sinous_n part_v than_o crude_a oplum_fw-la both_o because_o the_o earthy_a part_n that_o help_v to_o make_v up_o the_o bulk_n be_v take_v away_o in_o that_o preparation_n and_o because_o the_o 〈◊〉_d of_o wine_n imbibe_v the_o rosin_n more_o greedy_o than_o other_o principle_n of_o the_o opium_n so_o that_o every_o do_v must_v in_o proportion_n have_v much_o more_o rosin_n in_o it_o than_o crude_a opium_n therefore_o it_o be_v no_o wonder_n that_o it_o cause_v those_o ill_a effect_n more_o frequent_o since_o the_o rosin_n be_v most_o certain_o the_o cause_n thereof_o as_o have_v be_v and_o shall_v be_v more_o full_o and_o beyond_o all_o contradiction_n prove_v yet_o be_v this_o the_o preparation_n boast_v of_o by_o the_o blind_a and_o inadvertent_n world_n it_o will_v amaze_v nay_o terrify_v a_o man_n to_o see_v what_o great_a care_n be_v take_v to_o be_v sure_a to_o render_v opium_n mischievous_a by_o solicitous_o use_v spirit_n of_o wine_n in_o extract_a laudanum_n and_o then_o and_o not_o till_o then_o they_o boast_v of_o the_o preparation_n as_o charas_fw-la and_o very_o many_o other_o do_v calling_z it_o not_o without_o great_a ostentation_n and_o desperate_a folly_n their_o laudanum_n may_v it_o be_v they_o and_o none_o other_o a_o turk_n will_v be_v a_o madman_n to_o use_v it_o for_o crude_a opium_n because_o it_o have_v much_o more_o of_o the_o pernicious_a principle_n in_o it_o it_o be_v the_o common_a and_o much_o esteem_v way_n first_o to_o extract_v it_o out_o of_o water_n and_o then_o it_o be_v very_o good_a laudable_a and_o innocent_a but_o think_v nothing_o worth_a till_o they_o extract_v the_o rosin_n that_o be_v all_o leave_v behind_o by_o the_o water_n in_o spirit_n of_o wine_n and_o add_v it_o to_o the_o other_o then_o do_v they_o with_o great_a authority_n praise_v it_o that_o be_v when_o they_o have_v wise_o add_v the_o poison_n to_o the_o panacea_fw-la it_o be_v as_o if_o they_o add_v ratsbane_n to_o a_o cordial_n and_o not_o think_v the_o cordial_a worthy_a commendation_n till_o they_o have_v do_v so_o 4._o it_o appear_v that_o the_o rosin_n be_v
only_o in_o those_o membrane_n but_o also_o in_o the_o more_o exquisite_o dispose_v membrane_n for_o sensation_n at_o stomach_n and_o soon_o after_o all_o over_o the_o body_n 5._o it_o prevent_v and_o take_v away_o grief_n fear_v anxiety_n peevishness_n fretfulness_n etc._n etc._n for_o the_o aforesaid_a reason_n which_o cause_n a_o blithe_a gay_a and_o good_a humour_n promptitude_n courage_n etc._n etc._n for_o it_o be_v impossible_a to_o be_v gay_a and_o good_a humour_a serene_a cheerful_a courageous_a and_o magnanimous_a and_o at_o the_o same_o time_n sorrowful_a fearful_a peevish_a fretful_a etc._n etc._n if_o the_o bare_a sense_n of_o a_o ordinary_a meal_n of_o meat_n at_o stomach_n which_o cause_v but_o a_o slow_a pleasure_n in_o comparison_n with_o opium_n take_v off_o the_o peevishness_n fretfulness_n etc._n etc._n that_o the_o grievous_a sensation_n of_o hunger_n cause_n how_o much_o more_o must_v the_o intense_a and_o charm_a pleasure_n cause_v by_o opium_n that_o be_v so_o agreeable_a even_o far_o beyond_o wine_n itself_o as_o have_v be_v set_v forth_o take_v away_o all_o ill_a humour_n fretfulness_n peevishness_n etc._n etc._n obj._n but_o it_o may_v be_v say_v that_o sleepiness_n which_o depend_v also_o upon_o relaxation_n as_o the_o effect_n of_o pleasure_n do_v cause_v a_o peevish_a fretful_a humour_n as_o be_v common_o observe_v ans._n it_o be_v so_o far_o otherwise_o in_o the_o case_n of_o opium_n that_o it_o be_v quite_o contrary_a for_o 1._o the_o sleepy_a be_v not_o peevish_a unless_o you_o put_v they_o by_o some_o mean_v out_o of_o the_o pleasure_n of_o enjoy_v sleep_n or_o relaxation_n for_o if_o you_o let_v they_o alone_o they_o will_v not_o trouble_v you_o with_o peevishness_n nor_o any_o ill_a humour_n but_o it_o be_v the_o call_v they_o from_o their_o relaxed_a condition_n to_o the_o grievous_a task_n of_o contraction_n that_o vex_v they_o so_o that_o it_o be_v the_o want_n of_o continue_v under_o the_o relaxation_n that_o fret_v they_o and_o the_o more_o because_o the_o fatigue_n and_o tedium_n of_o contraction_n do_v put_v they_o upon_o the_o relief_n of_o sleep_n of_o which_o if_o disappoint_v they_o be_v much_o vex_v but_o in_o the_o case_n of_o opium_n you_o can_v so_o easy_o rob_v they_o of_o their_o pleasure_n which_o they_o carry_v continual_o within_o they_o in_o a_o uninterrupted_a manner_n unless_o some_o very_a grievous_a thing_n happen_v which_o cause_v more_o defensive_a contraction_n than_o the_o opium_n cause_v relaxation_n though_o even_o this_o also_o be_v general_o soon_o overcome_v by_o the_o pleasure_n continual_o invite_v the_o relaxation_n and_o promote_a it_o whereas_o the_o interruption_n thereof_o be_v transitory_a but_o at_o the_o worst_a it_o be_v but_o take_v more_o opium_n and_o the_o work_n be_v do_v for_o i_o observe_v that_o the_o do_v of_o opium_n must_v be_v sufficient_a to_o introduce_v such_o a_o sense_n of_o pleasure_n as_o cause_v a_o relaxation_n of_o the_o contraction_n cause_v by_o the_o grievance_n hence_o it_o be_v certain_a that_o a_o great_a pain_n require_v a_o large_a do_v of_o opium_n as_o have_v be_v intimate_v 6._o all_o know_v that_o pleasant_a diversion_n as_o music_n pleasant_a jest_n and_o story_n fine_a sight_n etc._n etc._n do_v cause_n euphory_n and_o a_o easy_a undergo_n of_o journey_n labour_n etc._n etc._n therefore_o if_o such_o interrupt_v transient_a and_o slight_a pleasure_n do_v it_o so_o much_o it_o will_v be_v easy_o grant_v i_o that_o a_o continual_a and_o more_o intense_a pleasure_n that_o be_v always_o present_a without_o any_o interruption_n or_o intermission_n as_o that_o of_o opium_n must_v cause_v a_o more_o eminent_a and_o permanent_a euphory_n proportion_v to_o the_o pleasure_n which_o cause_v relaxation_n prevent_v the_o fatigue_n or_o lassitude_n that_o be_v cause_v only_o by_o contraction_n either_o vigilative_a defensive_a or_o intentive_a as_o i_o have_v prove_v so_o that_o i_o do_v not_o conceive_v how_o the_o noctambuli_n or_o such_o as_o walk_v in_o their_o sleep_n can_v ever_o be_v tire_v if_o they_o travel_v ever_o so_o far_o if_o they_o can_v eat_v and_o drink_v because_o the_o relaxation_n of_o the_o sleep_v recruit_n they_o as_o much_o as_o they_o spend_v of_o spirit_n etc._n etc._n so_o person_n that_o cause_v such_o relaxation_n by_o opium_n and_o so_o repeat_v it_o as_o to_o maintain_v the_o relaxation_n can_v hardly_o be_v weary_a which_o be_v the_o true_a plain_a and_o mechanical_a reason_n why_o the_o turk_n and_o other_o eastern_a people_n do_v by_o the_o help_n of_o opium_n perform_v prodigious_a journey_n without_o be_v tire_v which_o may_v therefore_o in_o allusion_n to_o the_o noctambuli_n be_v call_v opiambuli_n or_o opambuli_n as_o be_v a_o kind_n of_o artificial_a noctambuli_n because_o they_o be_v much_o relax_v by_o the_o pleasure_n that_o opium_n cause_n as_o the_o other_o be_v by_o sleep_n qui_fw-la laetitiâ_fw-la aâ—iciuntur_fw-la say_v sanctorius_n nuâ—lam_n in_o itinere_fw-la defatigationem_fw-la sentiunt_fw-la that_o be_v the_o merry_a be_v not_o weary_a as_o the_o say_v be_v because_o mirth_n be_v pleasant_a cause_v relaxation_n as_o opium_n do_v in_o some_o measure_n note_v that_o as_o to_o all_o the_o forego_n serene_a and_o brisk_a effect_n a_o full_a and_o liberal_a perspiration_n which_o it_o also_o cause_n as_o will_v be_v show_v contribute_v much_o thereto_o a_o posteriori_fw-la for_o as_o fire_n burn_v slow_o and_o dull_o if_o the_o smoke_n do_v by_o any_o mean_n return_v upon_o it_o and_o very_o serene_a if_o not_o so_o it_o be_v with_o the_o flame_n of_o life_n if_o cloud_v with_o or_o clear_v from_o vapour_n by_o perspiration_n sanctor_n sect._n 7._o aph._n 17._o mâ—lancholia_fw-la superatur_fw-la liberâ_fw-la perspiratione_fw-la &_o aph._n 30._o 31._o edulia_n aperientia_fw-la gaudium_fw-la movent_fw-la that_o be_v such_o as_o open_v the_o pore_n and_o cause_n perspiration_n cause_n joy_n or_o mirth_n 7._o it_o lull_v soothe_v and_o as_o it_o be_v charm_v the_o mind_n with_o consent_n and_o acquiescence_n for_o the_o several_a reason_n couch_v in_o the_o premise_n and_o because_o the_o fine_a continual_a and_o charm_a pleasure_n of_o opium_n such_o as_o some_o glass_n of_o generous_a wine_n cause_v must_v needs_o have_v such_o a_o effect_n 8._o it_o quiet_v allay_v and_o compose_v all_o perturbation_n and_o commotion_n of_o the_o sensitive_a soul_n spirit_n etc._n etc._n 1._o because_o it_o so_o lull_v soothe_v and_o charm_n the_o sensitive_a soul_n as_o be_v aforesaid_a who_o be_v the_o original_a of_o all_o motion_n in_o the_o animal_n 2._o because_o all_o motion_n be_v by_o the_o relaxation_n proportionable_o abate_v as_o be_v demonstrate_v thus_o opium_n take_v off_o hysterick_n fit_v fever_n from_o commotion_n of_o the_o spirit_n convulsion_n stop_v hemerrhage_n or_o bleed_v &c._n &c._n 9_o it_o cause_v a_o relaxation_n of_o all_o the_o sensile_a part_n of_o the_o body_n by_o reason_n of_o the_o great_a and_o continual_a pleasure_n that_o it_o cause_n and_o how_o pleasure_n cause_v relaxation_n i_o have_v show_v in_o chap._n 14._o 10._o it_o cause_v indolence_n or_o exemption_n from_o pain_n by_o cause_v so_o high_a and_o last_a a_o pleasure_n 1._o because_o that_o pleasure_n take_v up_o the_o attention_n of_o the_o sensitive_a soul_n who_o delight_v in_o it_o 2._o because_o a_o sense_n of_o pleasure_n and_o pain_n can_v be_v at_o the_o same_o time_n in_o the_o same_o subject_a be_v they_o be_v contrary_n 3._o because_o the_o membrane_n be_v relax_v and_o the_o animal_n spirit_n expanded_a the_o impression_n of_o pain_n can_v be_v carry_v to_o the_o sensitive_a soul_n because_o they_o can_v convey_v impression_n smart_o be_v thus_o relax_v and_o expanded_a as_o have_v be_v demonstrate_v by_o the_o comparison_n of_o a_o gut_n half_n full_a of_o air_n etc._n etc._n and_o all_o impression_n of_o pain_n must_v be_v smart_n or_o else_o they_o be_v not_o impression_n of_o pain_n for_o gentle_a impression_n be_v such_o as_o belong_v to_o oil_n smooth_a and_o soft_a thing_n or_o when_o the_o animal_n spirit_n can_v hardly_o carry_v any_o impression_n but_o gentle_o as_o in_o sleep_n and_o other_o relaxation_n as_o that_o upon_o pleasure_n etc._n etc._n which_o be_v our_o case_n note_v that_o it_o will_v cause_v indolence_n without_o cause_v sleep_n because_o sleep_n require_v relaxation_n and_o quiet_a of_o the_o spirit_n but_o indolence_n require_v only_a relaxation_n as_o be_v show_v which_o always_o follow_v the_o charm_a pleasure_n of_o opium_n 11._o it_o stop_v moderate_v or_o palliate_n most_o flux_n and_o promote_v perspiration_n because_o the_o relaxation_n take_v away_o the_o sense_n of_o the_o irritation_n of_o humour_n which_o cause_v a_o contraction_n to_o squeeze_v they_o out_o and_o that_o the_o same_o relaxation_n open_v the_o pore_n to_o let_v the_o foam_n out_o which_o pass_v by_o their_o own_o levity_n upon_o the_o open_n of_o the_o pore_n nihil_fw-la magis_fw-la say_v sanctorius_n
sect._n 7._o aph._n 6._o reddit_fw-la liberam_fw-la perspirationem_fw-la quam_fw-la animi_fw-la consolatio_fw-la aut_fw-la voluptas_fw-la &_o aph._n 19_o animi_fw-la consolatio_fw-la quacunque_fw-la de_fw-la causâ_fw-la aperit_fw-la meatus_fw-la &_o largam_fw-la perspirationem_fw-la facit_fw-la now_o you_o may_v perceive_v why_o opium_n and_o good_a cordial_n do_v moderate_a flux_n by_o stool_n even_o before_o they_o be_v out_o of_o the_o stomach_n because_o the_o pleasure_n there_o cause_v relax_n all_o part_n and_o thereby_o cause_v a_o expansion_n of_o the_o animal_n spirit_n the_o sense_n of_o the_o irritation_n be_v lose_v because_o the_o expand_v spirit_n can_v carry_v the_o impression_n smart_o to_o the_o sensitive_a soul_n which_o must_v be_v to_o cause_v a_o sense_n of_o irritation_n or_o grievous_a sensation_n by_o the_o same_o reason_n only_o warm_a trencher_n apply_v to_o the_o belly_n or_o sit_v upon_o a_o warm_a stool_n etc._n etc._n moderate_v a_o looseness_n because_o the_o pleasure_n of_o the_o warmth_n relax_n and_o so_o take_v away_o a_o sense_n of_o the_o irritation_n by_o the_o aforesaid_a expansion_n of_o the_o spirit_n 12._o i_o have_v just_a now_o show_v how_o it_o promote_v insensible_a perspiration_n viz._n by_o the_o relaxation_n open_v the_o pore_n and_o let_v out_o the_o fume_n which_o i_o need_v not_o have_v mention_v again_o but_o for_o order_n sake_n that_o all_o may_v thereby_o see_v that_o i_o evade_v the_o explication_n of_o no_o effect_n nor_o indeed_o need_v i_o for_o they_o be_v now_o obvious_a enough_o even_o without_o my_o explication_n to_o any_o sagacious_a person_n so_o that_o the_o plainness_n may_v give_v great_a cause_n to_o pass_v over_o some_o untouched_a than_o the_o difficulty_n but_o it_o be_v not_o sit_v that_o either_o shall_v cause_v any_o omission_n in_o such_o a_o mighty_a concern_v that_o be_v never_o explicate_v and_o scarce_o ever_o think_v possible_a 13._o opium_n prevent_v shivering_n in_o ague_n fit_n because_o that_o for_o the_o reason_n aforesaid_a it_o take_v away_o the_o sense_n of_o the_o irritate_v humour_n that_o cause_v they_o 14._o it_o prevent_v and_o cure_v cold_n by_o the_o relaxation_n that_o its_o pleasure_n cause_n whereby_o the_o pore_n be_v keep_v very_o open_a and_o perspiration_n as_o be_v show_v promote_v beside_o that_o it_o prevent_v the_o sensation_n of_o hinder_v it_o to_o constringe_v the_o pore_n by_o cause_v a_o grievous_a sensation_n 15._o it_o cause_v a_o large_a and_o slow_a pulse_n because_o of_o the_o relaxation_n that_o the_o intense_a and_o continual_a pleasure_n cause_n by_o which_o the_o artery_n be_v widen_v and_o the_o motion_n make_v slow_a 1._o because_o the_o animal_n spirit_n be_v weaken_v by_o the_o relaxation_n of_o their_o vessel_n and_o their_o expansion_n thereupon_o 2._o because_o the_o sense_n of_o irritation_n by_o which_o the_o heart_n be_v solicit_v to_o move_v fast_o be_v lose_v 16._o it_o cause_v dryness_n in_o the_o mouth_n as_o sleep_n do_v 1._o because_o the_o dilatation_n of_o the_o glandule_n by_o the_o relaxation_n detain_v and_o suspend_v the_o humour_n and_o 2._o because_o the_o sensation_n be_v lessen_v the_o membrane_n that_o include_v the_o salival_n glandule_n be_v not_o irritate_v to_o contraction_n to_o squeeze_v out_o the_o saliva_n or_o spital_n 3._o because_o the_o pulse_n be_v slow_a to_o cause_v a_o extrusion_n of_o the_o humour_n 17._o it_o have_v most_o effect_n in_o warm_a and_o moist_a wether_n because_o both_o warmth_n and_o moisture_n promote_v relaxation_n by_o which_o opium_n do_v upon_o the_o account_n of_o the_o pleasure_n it_o cause_v perform_v its_o effect_n 18._o it_o have_v more_o effect_n upon_o fine_a and_o lax_n texture_n for_o the_o same_o reason_n and_o because_o their_o sensation_n be_v more_o nice_a and_o affect_v more_o with_o please_a or_o grieve_v thing_n therefore_o it_o affect_v child_n and_o woman_n especial_o the_o nice_n and_o delicate_a more_o than_o man_n which_o may_v be_v the_o reason_n why_o woman_n do_v not_o use_v opium_n in_o the_o eastern_a country_n as_o much_o as_o men._n 19_o it_o cause_v a_o efflorescence_n or_o redness_n of_o the_o skin_n as_o sleep_n or_o wine_n do_v because_o the_o skin_n be_v relax_v admit_v the_o blood_n to_o come_v into_o it_o very_o free_o as_o cold_a fear_v etc._n etc._n contract_v the_o part_n of_o the_o skin_n repel_v it_o or_o squeeze_v it_o out_o or_o back_o again_o thus_o person_n that_o drink_v much_o get_v red_a nose_n by_o frequent_a relaxation_n of_o the_o skin_n which_o widen_v the_o road_n of_o the_o blood_n more_o and_o more_o hence_o it_o be_v that_o the_o bag_n at_o a_o turky-cock_n neck_n be_v red_a when_o he_o be_v please_v and_o soon_o pale_a again_o when_o displease_v 20._o it_o affect_v the_o genus_fw-la nervosum_fw-la or_o animal_n spirit_n which_o be_v a_o common_a observation_n more_o than_o the_o blood_n because_o it_o operate_v by_o affect_v sensation_n wherein_o the_o nerve_n and_o membrane_n be_v most_o concern_v and_o not_o by_o alter_v the_o blood_n to_o which_o it_o bear_v no_o proportion_n to_o cause_v any_o remarkable_a effect_n note_v how_o plain_o this_o concession_n of_o all_o author_n confirm_v what_o i_o say_v viz._n that_o it_o do_v not_o operate_v as_o a_o alterative_a of_o the_o blood_n etc._n etc._n but_o by_o affect_v sensation_n as_o i_o have_v prove_v 21._o it_o increase_v seed_n in_o some_o measure_n because_o it_o administer_v a_o sal-volatile-oleosum_a of_o the_o same_o nature_n with_o it_o and_o by_o its_o titillation_n solicit_v and_o invite_v the_o send_n of_o its_o matter_n that_o way_n as_o be_v observable_a in_o such_o as_o use_v much_o titillation_n but_o to_o speak_v plain_o and_o mechanical_o i_o think_v that_o this_o main_o happen_v because_o of_o the_o relaxation_n of_o the_o part_n admit_v as_o be_v say_v of_o the_o efflorescence_n of_o the_o skin_n by_o relaxation_n the_o blood_n or_o material_n of_o seed_n more_o free_o into_o the_o testicle_n and_o all_o the_o seminary_n vessel_n especial_o be_v that_o the_o titillation_n cause_v a_o ostener_o empty_v of_o the_o same_o in_o order_n to_o receive_v those_o material_n with_o less_o opposition_n for_o quod_fw-la intus_fw-la est_fw-la prohibet_fw-la alienum_fw-la that_o be_v what_o be_v within_o hinder_v the_o entrance_n of_o other_o matter_n nothing_o can_v receive_v more_o than_o what_o it_o can_v contain_v but_o what_o be_v often_o empty_v can_v successive_o receive_v much_o 22._o it_o cause_v a_o great_a promptitude_n to_o venery_n erection_n etc._n etc._n especial_o if_o the_o do_v be_v large_a than_o ordinary_a because_o be_v of_o the_o same_o principle_n with_o animal_n seed_n and_o in_o all_o probability_n somewhat_o more_o titillate_v and_o of_o like_a principle_n though_o more_o gentle_a than_o cantharides_n it_o must_v high_o titillate_v those_o part_n and_o consequent_o cause_v a_o great_a promptitude_n to_o venery_n chap._n xviii_o the_o explication_n of_o the_o frequent_a though_o not_o constant_a effect_n of_o opium_n in_o a_o moderate_a do_v 1._o it_o cause_v sleep_n because_o it_o high_o dispose_v thereto_o by_o the_o relaxation_n that_o its_o pleasure_n cause_n thus_o music_n agreeable_a frication_n and_o many_o other_o pleasure_n nay_o all_o that_o be_v consistent_a with_o lie_v or_o sit_v still_o and_o silent_a incline_v we_o to_o sleep_n but_o none_o can_v compare_v with_o the_o sweet_a continual_a and_o transcendent_a pleasure_n of_o opium_n that_o we_o carry_v along_o with_o we_o for_o many_o hour_n whereas_o other_o pleasure_n be_v either_o remiss_a or_o interrupt_v or_o transient_a in_o their_o nature_n for_o continuance_n in_o gentle_a pleasure_n as_o the_o fall_n of_o water_n whistle_v of_o wind_n effect_n much_o towards_o sleep_n so_o intenseness_n do_v also_o though_o momentary_a as_o that_o of_o venus_n how_o much_o than_o must_v a_o continual_a and_o intense_a pleasure_n cause_n it_o especial_o when_o rest_n silence_n etc._n etc._n be_v add_v thereto_o note_v that_o sleep_n be_v so_o far_o from_o be_v a_o property_n of_o opium_n that_o it_o do_v not_o belong_v to_o it_o omni_n soli_fw-la or_o semper_fw-la yet_o people_n have_v general_o look_v upon_o sleep_n as_o such_o which_o cause_v many_o error_n 2._o it_o cause_v pleasant_a dream_n because_o the_o very_a sleep_n be_v cause_v and_o continue_v by_o pleasure_n when_o it_o be_v by_o opium_n which_o pleasure_n be_v all_o the_o time_n we_o sleep_v within_o we_o must_v needs_o suggest_v pleasant_a dream_n or_o none_o for_o how_o can_v sad_a and_o melancholy_a dream_n seize_v one_o that_o be_v in_o a_o gay_a and_o pleasant_a condition_n as_o far_o as_o one_o in_o sleep_n be_v capable_a thereof_o 3._o it_o stop_v vomit_v 1._o as_o it_o do_v other_o flux_n by_o take_v away_o the_o sense_n of_o irritation_n 2._o by_o high_o please_v and_o thereby_o quiet_v and_o compose_v the_o commotion_n of_o the_o stomach_n 3._o by_o relax_v it_o which_o oppose_v the_o
which_o look_v not_o unlike_o a_o apoplexy_n make_v author_n say_v that_o opium_n cause_v apoplexy_n such_o as_o escape_v death_n do_v so_o general_o by_o 34._o plentiful_a purge_v which_o be_v occasion_v by_o a_o great_a quantity_n of_o the_o rosin_n of_o opium_n meet_v a_o strong_a digestion_n and_o fix_a salt_n as_o have_v beeâ—_n say_v 35._o sweat_v that_o smell_n of_o the_o opium_n be_v cause_v 1._o by_o the_o openness_n of_o the_o pore_n by_o relaxation_n 2._o by_o plenty_n or_o at_o least_o sufficiency_n of_o moisture_n for_o that_o end_n for_o otherwise_o as_o be_v show_v it_o will_v be_v only_o insensible_a perspiration_n 3._o by_o the_o great_a quantity_n of_o volatile_a salt_n attenuate_v the_o humour_n 4._o by_o the_o strict_a intimate_a and_o even_o indissoluble_a specific_a union_n or_o combination_n of_o the_o volatile_a salt_n and_o oily_a part_n which_o make_v it_o hold_v its_o specific_a smell_n to_o the_o last_o 36._o violent_a itch_n in_o the_o skin_n must_v of_o necessity_n follow_v a_o great_a quantity_n of_o opium_n since_o it_o cause_v such_o itch_n as_o be_v show_v in_o a_o small_a quantity_n by_o the_o titillation_n of_o its_o volatile_a salt_n note_v that_o these_o effect_n do_v not_o all_o happen_v to_o all_o man_n that_o take_v it_o in_o a_o excessive_a do_v but_o some_o to_o one_o and_o some_o to_o other_o as_o be_v intimate_v in_o chap._n 5._o according_a as_o they_o be_v more_o or_o less_o trouble_v with_o the_o rosin_n quantity_n relaxation_n etc._n etc._n chap._n xxii_o the_o explication_n of_o the_o effect_n of_o a_o long_a and_o lavish_a use_n of_o opium_n as_o a_o excessive_a do_v of_o opium_n be_v intemperance_n for_o one_o time_n so_o a_o long_a and_o lavish_a use_n of_o it_o be_v a_o habitual_a intemperance_n for_o a_o long_a time_n therefore_o if_o you_o can_v not_o rational_o expect_v good_a effâ—s_n in_o that_o case_n any_o more_o than_o from_o the_o best_a wine_n take_v sudden_o in_o a_o vast_a quantity_n it_o follow_v that_o you_o can_v expect_v good_a effect_n from_o a_o habitual_a intemperate_a take_v of_o it_o any_o more_o than_o from_o a_o long_a and_o lavish_a drink_v of_o wine_n though_o both_o be_v excellent_o good_a in_o their_o kind_a but_o that_o the_o opium_n have_v the_o pernicious_a resinous_a part_n join_v with_o it_o there_o be_v nothing_o so_o good_a whereof_o a_o intemperate_a use_n be_v not_o mischievous_a god_n have_v so_o order_v it_o to_o deter_v from_o and_o punish_v intemperance_n and_o the_o abuse_n of_o his_o creature_n therefore_o ill_a effect_n be_v not_o always_o to_o be_v impute_v to_o the_o viciousness_n of_o the_o thing_n use_v but_o frequent_o of_o the_o person_n that_o imprudent_o use_v they_o 1._o relaxation_n and_o debility_n of_o all_o part_n be_v contract_v by_o the_o habitual_a over-relaxing_a thereof_o by_o the_o lavish_a use_n of_o opium_n 2._o a_o inhability_n of_o do_v any_o thing_n without_o it_o be_v contract_v by_o the_o habitual_a pleasure_n comfort_n promptitude_n and_o euphory_n it_o cause_v when_o take_v without_o which_o the_o sensitive_a soul_n become_v lazy_a listless_a and_o averse_a to_o all_o action_n it_o be_v as_o iâ—_n a_o man_n use_v to_o dance_n to_o excellent_a music_n be_v require_v to_o do_v it_o without_o any_o music_n at_o all_o nor_o as_o much_o as_o thought_n of_o it_o or_o mumble_v it_o within_o himself_o or_o that_o one_o who_o drink_v nothing_o but_o wine_n and_o eat_v the_o best_a shall_v be_v sudden_o deny_v both_o and_o force_v to_o live_v upon_o bread_n and_o water_n or_o that_o such_o as_o always_o take_v tobacco_n at_o their_o study_n shall_v be_v sudden_o debar_v thereof_o and_o require_v to_o study_v without_o it_o how_o very_o listless_a will_v a_o man_n be_v in_o such_o case_n though_o hardly_o any_o of_o the_o comparison_n come_v up_o to_o that_o of_o opium_n because_o of_o the_o charm_a pleasure_n mighty_a euphory_n and_o promptitude_n that_o it_o cause_n it_o be_v as_o if_o one_o be_v support_v and_o whole_o depend_v upon_o cordial_n and_o sudden_o deny_v they_o etc._n etc._n 3._o a_o inhability_n of_o get_v up_o in_o the_o morning_n till_o it_o be_v take_v and_o begin_v to_o operate_v proceed_v from_o the_o same_o cause_n a_o mechanical_a reason_n may_v be_v expect_v here_o also_o as_o to_o these_o matter_n but_o it_o will_v hardly_o bear_v it_o any_o more_o than_o how_o the_o will_n or_o appetite_n cause_v the_o first_o impulse_n towards_o voluntary_a moti_fw-la n_o all_o that_o can_v be_v say_v be_v that_o without_o the_o opium_n the_o sensitive_a soul_n be_v when_o he_o do_v any_o thing_n to_o act_v under_o the_o toil_n and_o difficulty_n of_o a_o full_a vigilative_a contraction_n as_o be_v awake_a intentive_a contraction_n as_o act_v and_o defensive_a contraction_n as_o be_v grieve_v when_o the_o operation_n of_o opium_n be_v over_o as_o after_o veneral_a pleasure_n etc._n etc._n so_o that_o now_o he_o labour_v under_o the_o great_a disadvantage_n and_o drudgery_n of_o all_o the_o three_o contraction_n whereas_o by_o the_o pleasure_n fine_a titillation_n of_o opium_n and_o relaxation_n consequential_a thereunto_o he_o be_v ease_v of_o all_o the_o defensive_a contraction_n which_o be_v the_o most_o grievous_a and_o in_o great_a measure_n of_o the_o vigilative_a as_o have_v be_v show_v which_o make_v work_v journey_a etc._n etc._n very_o easy_a to_o he_o therefore_o it_o be_v as_o if_o one_o that_o delight_v in_o music_n dance_v to_o charm_a melody_n in_o belove_a company_n with_o please_a refection_n of_o wine_n etc._n etc._n and_o in_o the_o other_o case_n as_o if_o one_o labour_v in_o grief_n or_o pain_n now_o suppose_v that_o one_o use_v never_o to_o act_n or_o work_n without_o such_o mighty_a pleasant_a advantage_n and_o cause_n of_o euphory_n be_v require_v to_o act_v under_o the_o pressure_n of_o the_o three_o contraction_n or_o in_o grief_n or_o pain_n how_o listless_a will_v he_o be_v to_o act_n work_n get_v up_o etc._n etc._n 4._o a_o dull_a moapish_a and_o heavy_a disposition_n must_v be_v the_o effect_n unless_o it_o be_v while_o they_o please_v comfort_n and_o enliven_v themselves_o by_o the_o opium_n because_o their_o brain_n be_v habitual_o over_o relax_v which_o be_v the_o very_a case_n of_o old_a drunkard_n who_o have_v as_o it_o be_v say_v drink_v away_o their_o part_n by_o such_o a_o habitual_a relaxation_n of_o the_o brain_n which_o overmuch_o sleep_v cause_n also_o upon_o the_o account_n of_o the_o like_a relaxation_n therefore_o they_o must_v be_v moapish_a till_o the_o please_a titillation_n of_o opium_n enlivens_fw-la they_o 5._o diminution_n of_o appetite_n be_v cause_v by_o a_o habitual_a relaxation_n of_o the_o stomach_n take_v away_o its_o sensation_n and_o suspend_v the_o menstruum_fw-la from_o flow_v to_o it_o as_o free_o as_o it_o shall_v and_o will_v if_o there_o be_v a_o due_a contraction_n to_o squeeze_v it_o out_o 6._o weakness_n of_o digestion_n happen_v from_o the_o same_o cause_n 7._o dropsy_n be_v cause_v by_o the_o relaxation_n weaken_v the_o part_n and_o make_v they_o thereby_o susceptible_a of_o humour_n as_o also_o by_o diminution_n of_o appetite_n and_o digestion_n as_o in_o old_a drunkard_n 8._o decay_n of_o part_n or_o wit_n happen_v from_o habitual_a relaxation_n of_o the_o brain_n and_o its_o membrane_n as_o in_o old_a drunkard_n 9_o weakness_n of_o memory_n proceed_v from_o the_o same_o cause_n as_o in_o old_a drunkard_n 10._o stoop_v in_o the_o back_n be_v cause_v by_o the_o habitual_a relaxation_n of_o the_o part_n which_o weaken_v and_o cause_v they_o to_o comply_v with_o our_o tendency_n and_o use_v of_o bend_v forward_o and_o yield_v to_o the_o great_a weight_n that_o be_v general_o speak_v on_o the_o foreside_n of_o the_o backbone_n or_o perpendicular_a so_o that_o stoop_v must_v gradual_o follow_v those_o conspire_a cause_n as_o it_o do_v in_o habitual_a drunkard_n who_o part_n be_v relax_v 11._o early_o decrepiteness_n must_v proceed_v from_o the_o aforesaid_a relaxation_n spoil_v the_o tone_n of_o part_n and_o cause_v want_n of_o appetite_n digestion_n etc._n etc._n in_o the_o manner_n before_o show_v 12._o shortness_n of_o life_n must_v be_v the_o effect_n of_o the_o same_o cause_n 13._o acrimony_n of_o blood_n proceed_v from_o the_o abundance_n of_o acrimonious_a volatile_a salt_n take_v in_o the_o opium_n wherein_o it_o be_v much_o more_o acrimonious_a than_o our_o natural_a volatile_a salt_n and_o in_o great_a quantity_n proportionable_o therefore_o it_o can_v be_v no_o wonder_n that_o 14._o it_o excite_v inclination_n to_o venery_n by_o that_o acrimonious_a salt_n which_o be_v analogous_a to_o that_o of_o cantharides_n aunt_n bee_n etc._n etc._n 15._o frequent_a inclination_n to_o make_v water_n be_v also_o a_o know_a and_o common_a effect_n of_o such_o a_o salt_n by_o its_o irritate_v and_o solicit_v the_o bladder_n etc._n etc._n 16._o priapism_n
opium_n extract_v out_o of_o spirit_n of_o wine_n to_o make_v it_o worse_o than_o when_o crude_a therefore_o have_v sometime_o ill_a effect_n especial_o when_o use_v alone_o in_o the_o form_n of_o a_o pill_n in_o a_o large_a do_v as_o be_v say_v 10._o philonium_fw-la magistrale_fw-la be_v also_o to_o be_v reject_v because_o the_o opium_n be_v prepare_v in_o spirit_n of_o wine_n and_o benjamin_n add_v which_o be_v resinous_a 11._o philon._n rom._n &_o persic_a be_v tolerable_a because_o the_o opium_n be_v disgregated_a and_o mix_v as_o galen_n will_v have_v it_o among_o much_o and_o several_a other_o thing_n which_o keep_v its_o resinous_a part_n from_o coalescence_n ii_o as_o to_o its_o form_n 1._o a_o pilular_a form_n of_o crude_a opium_n or_o any_o resinous_a preparation_n thereof_o wherein_o the_o rosin_n be_v not_o due_o subdue_v segregated_a alter_v or_o correct_v be_v as_o have_v be_v show_v the_o most_o pernicious_a 2._o the_o form_n of_o a_o electuary_n be_v commendable_a it_o be_v in_o small_a quantity_n mix_v therein_o with_o many_o or_o much_o other_o thing_n that_o prevent_v the_o coalescence_n of_o the_o râ—sin_n we_o particle_n 3._o a_o liquid_a form_n be_v general_o good_a because_o the_o part_n as_o in_o a_o tincture_n of_o opium_n in_o spirit_n of_o wine_n be_v sever_v and_o segiegated_a yet_o it_o be_v not_o so_o very_o safe_a where_o the_o râ—sin_n be_v not_o separate_v because_o if_o care_n be_v not_o take_v as_o have_v be_v direct_v the_o resinous_a particle_n may_v be_v precipitate_v at_o stomach_n and_o so_o coalesce_v and_o stick_v to_o it_o 4._o the_o operation_n of_o opium_n be_v quick_a in_o a_o liquid_a form_n but_o more_o last_a in_o a_o solid_a form_n especial_o if_o the_o opium_n be_v resinous_a which_o though_o noxious_a in_o general_n yet_o have_v the_o advantage_n of_o duration_n where_o it_o may_v be_v bear_v as_o in_o person_n of_o a_o robu_v texture_n and_o good_a digestion_n or_o where_o custom_n have_v take_v off_o its_o grievounsess_n as_o you_o find_v in_o habitual_a tobaco-taking_a etc._n etc._n 5._o the_o liquid_a panacea_fw-la of_o opium_n be_v better_a for_o alteration_n because_o it_o be_v the_o first_o fruit_n of_o the_o opium_n and_o more_o sincere_a and_o unaltered_a by_o fire_n than_o the_o solid_a but_o 6._o the_o solid_a panacea_fw-la be_v better_a where_o a_o stay_n at_o stomach_n and_o the_o intestine_n be_v convenient_a as_o in_o stop_v of_o vomit_v looseness_n etc._n etc._n to_o be_v brief_a 7._o liquid_a form_n shall_v be_v always_o give_v in_o foul_a stomach_n where_o the_o digestion_n be_v weak_a in_o fever_n and_o when_o a_o nimble_a operation_n be_v requisite_a iii_o as_o to_o its_o dose_n 1._o the_o mean_a or_o middle_n do_v be_v general_o to_o be_v use_v and_o where_o there_o be_v no_o direction_n to_o the_o contrary_n 2._o the_o mean_a dose_n may_v serve_v except_o in_o violent_a pain_n or_o where_o much_o of_o the_o opiate_n be_v lose_v as_o it_o happen_v very_o often_o in_o vomit_v or_o looseness_n or_o to_o excite_v venery_n because_o those_o part_n be_v remote_a and_o require_v a_o very_a sensible_a titillation_n but_o as_o to_o these_o matter_n you_o will_v have_v particular_a direction_n in_o the_o respective_a case_n in_o the_o follow_a chapter_n that_o treat_v thereof_o in_o a_o special_a manner_n 3._o the_o do_v must_v be_v proportionable_o less_o in_o the_o fine_a and_o lax-textured_n child_n woman_n warm_a and_o moist_a wether_n weak_a stomach_n person_n much_o debilitate_a or_o overtired_n with_o work_n labour_n disease_n etc._n etc._n iv_o as_o to_o its_o vehicle_n 1._o it_o shall_v general_o unless_o there_o be_v particular_a cause_n to_o the_o contrary_a be_v pleasant_a and_o agreeable_a to_o the_o taste_n and_o stomach_n that_o it_o may_v rather_o conspire_v with_o the_o opiate_n to_o please_v the_o membrane_n etc._n etc._n than_o contradict_v the_o sensitive_a pleasure_n that_o it_o cause_n 2._o it_o shall_v not_o be_v a_o acid_n because_o it_o infringe_n the_o volatile_a nature_n of_o opium_n except_o some_o particular_a case_n require_v it_o which_o will_v be_v see_v hereafter_o 3._o it_o shall_v not_o be_v a_o volatilo-saline_a especial_o to_o cause_v sleep_n or_o because_o that_o may_v render_v it_o too_o acrimonious_a or_o pungent_a and_o so_o hinder_v sleep_n composure_n etc._n etc._n 4._o it_o shall_v not_o be_v lixivial_a because_o its_o fix_a nature_n oppose_v the_o volatile_a except_o it_o be_v where_o the_o opiate_n be_v resinous_a to_o help_v its_o dissolution_n therefore_o 5._o wine_n or_o ferment_v liquor_n cordial_n water_n or_o smooth_a and_o pleasant_a liquid_n as_o emulsion_n milk_n and_o water_n water_n and_o sugar_n etc._n etc._n will_v be_v the_o most_o proper_a general_o speak_v 6._o the_o resinous_a opiate_n shall_v be_v always_o give_v in_o sulphureous_a spirit_n wâ—ne_n or_o strong_a liquor_n or_o in_o a_o lixivial_a vehicle_n or_o rather_o in_o both_o mix_v or_o in_o a_o rear_n yolk_n of_o a_o egg_n or_o fine_o powder_v and_o well_o mix_v with_o electuary_n bolus_n conserve_n thick_a syrup_n pulp_n or_o any_o thing_n that_o be_v innocent_a and_o of_o a_o good_a consistence_n to_o keep_v the_o resinous_a particle_n asunder_o and_o to_o prevent_v their_o coalescence_n for_o which_o end_n i_o judge_v that_o good_a white_a sâ—p_n must_v be_v because_o of_o the_o alkali_n its_o slipp'riness_n and_o aptitude_n to_o join_v with_o the_o rosin_n a_o good_a vehicle_n the_o opium_n and_o scrape_n of_o the_o soap_n be_v mix_v with_o a_o little_a rose-water_n and_o what_o else_o you_o think_v fit_a to_o render_v they_o more_o acceptable_a by_o pound_v they_o in_o a_o mortar_n for_o a_o good_a while_n to_o a_o intimate_a mixture_n v._o as_o to_o time_n 1._o give_v the_o liquid_a form_n half_a a_o hour_n at_o least_o or_o a_o hour_n before_o the_o time_n you_o will_v have_v they_o operate_v 2._o give_v the_o solid_a form_n a_o hour_n or_o a_o hour_n and_o a_o half_a before_o you_o will_v have_v they_o operate_v it_o be_v very_o silly_a not_o to_o give_v they_o till_o the_o very_a time_n that_o they_o shall_v operate_v as_o it_o be_v usual_a at_o bedtime_n when_o they_o shall_v be_v then_o operate_a and_o cause_v sleepiness_n that_o the_o rest_n and_o ease_n of_o lie_v down_o may_v concur_v with_o it_o whereas_o if_o people_n be_v unapt_a to_o sleep_v as_o general_o they_o be_v who_o take_v opium_n they_o not_o take_v it_o till_o bedtime_n lie_v toss_v and_o tumble_v grow_v uneasy_a and_o restless_a and_o the_o bed_n hard_o and_o in_o a_o great_a part_n of_o the_o year_n too_o hot_a before_o the_o opium_n operate_v so_o that_o the_o opium_n can_v take_v effect_n by_o reason_n of_o disquietude_n so_o the_o person_n lie_v all_o or_o most_o part_n of_o the_o night_n without_o any_o sleep_n whereas_o if_o it_o be_v so_o give_v as_o to_o cause_v a_o great_a sleepiness_n by_o the_o time_n they_o go_v to_o bed_n their_o lie_v still_o a_o very_a little_a time_n which_o they_o be_v then_o apt_a to_o and_o the_o bed_n be_v soft_a easy_a cool_a and_o pleasant_a they_o immediate_o sleep_v and_o their_o spirit_n be_v compose_v continue_v their_o sleep_n all_o or_o most_o part_n of_o the_o night_n therefore_o i_o have_v often_o come_v where_o people_n have_v not_o sleep_v though_o they_o take_v a_o opiate_n at_o bedtime_n and_o give_v they_o the_o very_a same_o a_o convenient_a time_n before_o and_o they_o have_v sweet_o sleep_v to_o their_o heart_n desire_n and_o refreshment_n 4._o give_v opiate_n as_o to_o meal_n at_o least_o 3_o hour_n before_o and_o after_o they_o or_o about_o the_o middle_a time_n between_o they_o if_o it_o be_v in_o the_o daytime_n or_o when_o the_o stomach_n be_v near_o empty_a or_o but_o little_a or_o light_a matter_n in_o it_o which_o if_o gentle_a and_o agreeable_a will_v help_v man_n to_o sleep_v but_o great_a repletion_n and_o perfect_a emptiness_n or_o hunger_n which_o be_v a_o grievous_a sensation_n do_v disturb_v or_o hinder_v sleep_n 5._o opiate_n may_v and_o have_v prove_v inconvenient_a before_o or_o after_o let_v of_o blood_n and_o hemorrhage_n especial_o if_o the_o evacuation_n be_v large_a and_o sudden_a the_o reason_n be_v because_o though_o person_n be_v very_o dispirited_a and_o so_o much_o incline_v to_o sleep_n of_o themselves_o may_v sleep_v too_o much_o and_o dangerous_o and_o because_o opium_n relax_v hinder_v the_o vessel_n due_o to_o contract_v upon_o the_o remain_a blood_n which_o may_v cause_v a_o discontinuance_n of_o its_o stream_n by_o reason_n that_o the_o diminish_v blood_n may_v not_o suffice_v to_o fill_v up_o the_o relaxed_a vessel_n though_o this_o may_v seldom_o happen_v because_o the_o compressure_n of_o the_o air_n be_v appoint_v by_o most_o wise_a providence_n to_o close_v all_o our_o vessel_n in_o such_o case_n but_o it_o must_v be_v better_a do_v when_o the_o
that_o when_o people_n be_v in_o a_o untoward_a condition_n or_o as_o they_o call_v it_o out_o of_o sod_n the_o next_o day_n after_o drink_v man_n often_o advise_v take_v the_o hair_n of_o the_o same_o dog_n that_o be_v drink_v some_o of_o the_o same_o wine_n or_o liquor_n it_o be_v best_o for_o they_o to_o use_v it_o as_o i_o just_a now_o direct_v for_o their_o case_n upon_o the_o good_a effect_n of_o the_o wine_n cease_v be_v much_o like_a that_o upon_o the_o go_n off_o of_o the_o operation_n of_o opium_n which_o may_v also_o in_o this_o case_n be_v use_v instead_o of_o wine_n to_o procure_v a_o better_a and_o blither_n condition_n for_o that_o day_n that_o use_v to_o be_v very_o troublesome_a to_o drinker_n 3._o note_v that_o good_a preparation_n of_o opium_n may_v be_v convenient_o use_v to_o horse_n to_o prevent_v their_o be_v tire_v or_o take_v off_o their_o weariness_n and_o cause_v they_o to_o go_v on_o but_o i_o will_v not_o advise_v any_o preparation_n in_o this_o case_n but_o the_o liquid_a panacea_fw-la in_o good_a ale_n or_o beer_n and_o that_o only_a in_o the_o same_o quantity_n as_o be_v use_v to_o man_n till_o far_a experience_n embolden_v the_o practice_n by_o such_o mean_n i_o can_v doubt_v it_o any_o jade_n may_v be_v make_v to_o appear_v lively_a go_v well_o etc._n etc._n chap._n xxxii_o of_o the_o use_n of_o the_o panacea_fw-la etc._n etc._n to_o compose_v the_o sensitive_a soul_n spirit_n etc._n etc._n i_o have_v show_v how_o and_o why_o it_o compose_v and_o quiet_v the_o sensitive_a soul_n spirit_n blood_n stomach_n etc._n etc._n and_o by_o that_o mean_n allay_v all_o the_o fury_n commotion_n perturbation_n and_o turbulent_a exorbitance_n thereof_o and_o that_o often_o without_o sleep_n but_o much_o better_a with_o it_o it_o follow_v therefore_o 1._o that_o it_o prevent_v and_o take_v off_o all_o fret_n and_o turbulent_a passion_n of_o the_o sensitive_a soul_n as_o anger_n uneasy_a agitation_n and_o toss_v of_o the_o mind_n peevishness_n fretfulness_n discontent_n disquietude_n dissatisfaction_n murmur_n turmoiling_n and_o vexatious_a thought_n anxiety_n solicitude_n etc._n etc._n and_o all_o the_o evil_a effect_n thereof_o as_o watch_n waste_v of_o spirit_n or_o strength_n lossitude_n hypochondriacal_a melancholy_n cachexy_n scurvy_n etc._n etc._n but_o these_o last_o belong_v most_o proper_o to_o its_o alterative_a faculty_n or_o virtue_n 2._o all_o involuntary_a furious_a agitation_n of_o the_o sensitive_a soul_n and_o spirit_n as_o madness_n more_o especial_o melancholy_a madness_n or_o such_o as_o proceed_v from_o grievous_a thought_n or_o apprehension_n loss_n cross_n despair_n fear_n terror_n or_o the_o like_a but_o they_o be_v not_o so_o good_a in_o merry_a madness_n as_o those_o from_o joy_n venereal_a fury_n and_o suchlike_a which_o answer_v the_o great_a dispute_n about_o opiate_n in_o madness_n delirium_n epileptical_a fit_n convulsion_n general_a and_o particular_a as_o those_o of_o the_o head_n rise_v of_o the_o light_n vomit_n hiccough_n sabbing_n kecking_n convulsive_a asthma_n palpitation_n and_o tremble_n of_o the_o heart_n shake_v and_o shivering_n upon_o fear_n terror_n cold_a pain_n ague-fits_a convulsive_a colick_n hysterick_n fit_v iliack_a passion_n etc._n etc._n 3._o all_o fever_n and_o fret_n of_o humour_n that_o happen_v from_o any_o of_o the_o aforesaid_a cause_n or_o from_o any_o violent_a motion_n voluntary_a or_o involuntary_a as_o labour_n run_v hew_v fight_a or_o any_o vehement_a exercise_n ratling_n toss_n concussion_n in_o coach_n wagon_n boat_n in_o stormy_a wether_n violent_a ride_v etc._n etc._n or_o from_o heat_n of_o fire_n sun_n bath_n hothouse_n bagnio_n crowd_n lie_v too_o many_o in_o one_o bed_n or_o with_o too_o much_o clothes_n or_o from_o grievous_a sensation_n irritation_n or_o pain_n as_o fever_n upon_o inflammation_n abscess_n bubo_n stone_n colic_n cardialgia_n wound_n fracture_n dislocation_n confusion_n amputation_n lithotomy_n paracentesis_n or_o any_o painful_a operation_n of_o the_o noble_a art_n of_o chirurgery_n agony_n or_o pain_n of_o the_o smallpox_n as_o its_o second_o fever_n and_o the_o like_a or_o from_o flux_n as_o tedious_a and_o turbulent_a vomit_n diarrheas_n dysentery_n cholera_n iliack_a passion_n artificial_a purge_v and_o all_o symptomatick_a or_o immaterial_a fever_n whatsoever_o which_o either_o never_o have_v any_o matter_n but_o proceed_v from_o such_o agitate_a cause_n as_o i_o mention_v or_o remain_v as_o some_o do_v after_o the_o grieve_v matter_n be_v carry_v off_o by_o vomit_v purge_v etc._n etc._n i_o forbear_v mention_v pleurisy_n and_o peripneumonia_n among_o the_o fever_n that_o it_o prevent_v or_o take_v off_o because_o there_o be_v great_a dispute_n whether_o opiate_n be_v convenient_a in_o those_o case_n which_o i_o hope_v to_o determine_v unless_o it_o be_v when_o the_o say_v distemper_n be_v come_v to_o that_o pass_n that_o it_o be_v dangerous_a to_o cause_v sleep_n or_o take_v away_o any_o of_o the_o sense_n of_o the_o irritation_n of_o the_o matter_n to_o be_v expectorate_v lest_o it_o shall_v be_v too_o much_o amass_v in_o the_o bronchias_n or_o windpipe_n and_o so_o choke_v the_o person_n i_o see_v no_o cause_n to_o forbid_v they_o any_o more_o than_o sleep_v or_o opiate_n in_o other_o inflammation_n wherein_o they_o be_v high_o beneficial_a to_o give_v ease_n cause_n sleep_n compose_v the_o spirit_n and_o take_v off_o or_o at_o least_o moderate_a the_o fever_n but_o i_o see_v many_o good_a reason_n to_o use_v they_o 1._o because_o as_o a_o sal-volatile-oleosum_a they_o reserate_v and_o resolve_v clammy_a humour_n and_o be_v so_o agreeable_a in_o principle_n as_o menstraums_n shall_v be_v to_o the_o thing_n to_o be_v resolve_v i_o can_v doubt_v but_o red_a poppy_n be_v upon_o experience_n state_v a_o specific_a in_o those_o case_n for_o that_o reason_n 2._o because_o these_o distemper_n as_o hypocrates_n speak_v be_v from_o a_o segregation_n of_o humour_n by_o agitation_n etc._n etc._n and_o opiate_n excellent_a composer_n thereof_o 3._o because_o they_o be_v such_o great_a discusser_n and_o 4._o open_v the_o pore_n to_o let_v the_o discuss_v matter_n quite_o out_o of_o the_o body_n 5._o because_o it_o may_v be_v that_o by_o its_o relaxation_n upon_o such_o resolution_n the_o lodge_v matter_n may_v be_v cause_v to_o flow_v off_o and_o circulate_v again_o and_o so_o be_v gradue_v discuss_v and_o carry_v off_o by_o the_o open_a pore_n 6._o because_o it_o envigorate_v nature_n to_o perform_v those_o thing_n and_o 7._o give_v ease_n and_o recruit_v of_o the_o spirit_n by_o sleep_n so_o that_o all_o thing_n consider_v i_o think_v as_o experience_n assure_v we_o that_o red_a poppy_n or_o opiate_n in_o due_a quantity_n be_v the_o very_o best_a remedy_n that_o can_v be_v use_v hence_o it_o be_v that_o wedelius_n call_v opium_n a_o antipleuritick_n specific_a he_o have_v observe_v as_o i_o and_o other_o have_v do_v that_o the_o whole_a course_n of_o the_o disease_n and_o expectoration_n will_v succeed_v much_o better_a by_o their_o use._n he_o add_v also_o that_o he_o have_v very_o often_o cure_v they_o by_o its_o help_n without_o let_v of_o blood_n which_o be_v a_o infallible_a sign_n of_o their_o good_a effect_n since_o the_o pleurisy_n can_v hardly_o be_v cure_v without_o bleed_v i_o can_v see_v how_o a_o effect_n that_o bear_v such_o analogy_n to_o sleep_n can_v do_v any_o more_o harm_n than_o sleep_n etmuller_n also_o advise_v the_o give_v of_o opiate_n not_o only_o in_o the_o beginning_n but_o also_o during_o the_o increase_n of_o the_o pleurisy_n or_o peripneumoniae_fw-la so_o that_o i_o conclude_v that_o they_o be_v of_o excellent_a use_n in_o those_o disease_n unless_o it_o be_v when_o sleep_n or_o they_o may_v cause_v too_o much_o insensibleness_n of_o the_o bronchias_n and_o so_o retard_v expectoration_n when_o the_o case_n be_v such_o that_o the_o want_v thereof_o may_v endanger_v the_o person_n be_v be_v choke_v we_o have_v also_o many_o history_n of_o person_n cure_v in_o other_o fever_n by_o large_a dose_n of_o opiate_n i_o suppose_v that_o resinous_a opiate_n cause_v vomit_v and_o great_a disturbance_n by_o reason_n of_o ill_a digestion_n in_o those_o case_n may_v be_v one_o great_a cause_n of_o people_n fear_n and_o jeolousy_n in_o give_v opiate_n which_o be_v easy_o prevent_v by_o give_v liquid_a opiate_n void_a of_o any_o resinous_a particle_n as_o the_o liquid_a panacea_fw-la etc._n etc._n 4._o it_o do_v by_o compose_v quiet_v and_o appease_v the_o motion_n and_o perturbation_n of_o the_o blood_n conduce_v much_o to_o the_o stop_n of_o its_o efflux_n in_o hemorrhage_n or_o bleeding_n that_o be_v unnatural_a as_o at_o nose_n in_o spit_v and_o vomit_v of_o blood_n bleed_v at_o the_o hemorrhoid_v in_o dysentery_n piss_v of_o blood_n etc._n etc._n and_o sometime_o in_o profuse_a menses_fw-la when_o they_o happen_v from_o a_o fever_n or_o too_o much_o motion_n of_o the_o blood_n and_o
by_o titillation_n upon_o the_o account_n of_o the_o volatile_a salt_n which_o appear_v by_o its_o exciting_a to_o venery_n at_o the_o same_o time_n as_o all_o those_o volatiles_fw-la do_v 16._o it_o be_v cause_v vomit_n as_o it_o often_o do_v be_v a_o undoubted_a sign_n of_o its_o volatile_a salt_n for_o all_o vegetable_a vomit_n be_v such_o upon_o that_o account_n unless_o it_o be_v such_o as_o may_v move_v vomit_v mere_o by_o their_o be_v loathe_v or_o nauseated_a which_o only_o cause_v some_o particular_a person_n to_o vomit_v but_o such_o as_o be_v constant_a vomitory_n be_v so_o upon_o the_o account_n of_o their_o volatile_a salt_n as_o asaerabocea_n groundsil_n foxâ—loves_n squill_n etc._n etc._n give_v in_o a_o sufficient_a quantity_n 17._o it_o be_v lively_a effect_n as_o courage_n etc._n etc._n prove_v the_o same_o 18._o all_o author_n that_o have_v be_v curious_a do_v agree_v that_o opium_n abound_v with_o volatile_a salt_n as_o helmont_n lemery_n le_fw-fr febure_n wedelius_n and_o indeed_o every_o one_o that_o ever_o i_o read_v though_o most_o of_o they_o attribute_v its_o effect_n to_o a_o sulphur_n which_o make_v their_o testimony_n of_o its_o volatile_a salt_n the_o strong_a as_o be_v force_v to_o confess_v it_o against_o their_o hypothesise_n 19_o after_o its_o fermentation_n with_o leaven_n in_o a_o sand_n heat_v for_o 14_o day_n it_o afford_v a_o volatile_a salt_n in_o good_a quantity_n but_o mix_v with_o oil_n which_o be_v separate_v from_o it_o by_o dissolution_n in_o water_n filtring_n etc._n etc._n 20._o it_o be_v spirit_n ferment_n with_o acid_n therefore_o be_v volatile_a last_o to_o pin_n up_o all_o if_o you_o either_o chemical_o analyse_v it_o by_o fire_n or_o set_v it_o to_o crystalize_v after_o it_o be_v evaporate_v to_o a_o due_a condition_n so_o to_o do_v it_o afford_v a_o great_a quantity_n of_o volatile_a salt_n therefore_o it_o be_v pass_v all_o manner_n of_o doubt_n for_o which_o end_n i_o have_v the_o long_o and_o more_o particular_o insist_v upon_o this_o point_n that_o it_o be_v high_o impregnate_v with_o volatile_a salt_n but_o as_o i_o say_v in_o the_o last_o chapter_n it_o be_v not_o enough_o for_o it_o to_o have_v volatile_a salt_n but_o it_o must_v be_v such_o as_o exceed_v our_o own_o or_o other_o animal_n in_o activity_n briskness_n etc._n etc._n by_o reason_n of_o quantity_n or_o quality_n or_o both_o that_o it_o may_v tickle_v up_o excite_v and_o cause_v a_o fine_a and_o agreeable_a ovation_n or_o glow_v in_o our_o spirit_n which_o as_o be_v show_v be_v very_o pleasant_a as_o in_o the_o case_n of_o sem._n viril_n especial_o when_o agitate_a by_o warmth_n frication_n or_o such_o actuate_a cause_n second_o it_o manifest_o appear_v that_o the_o volatile_a salt_n of_o opium_n exceed_v we_o in_o activity_n briskness_n etc._n etc._n 1._o by_o its_o exulcerate_v or_o blister_v quality_n especial_o if_o it_o be_v very_o good_a opium_n 2._o by_o its_o psilothrick_n quality_n to_o cause_v the_o hair_n to_o shed_v 3._o by_o its_o irritate_v to_o venery_n in_o so_o eminent_a a_o degree_n as_o cantharides_n bee_n pismire_n etc._n etc._n do_v and_o even_o beyond_o the_o ordinary_a course_n of_o sem._n virile_a which_o be_v most_o saturate_v with_o volatile_a salt_n of_o any_o part_n of_o the_o animal_n as_o appear_v by_o its_o dissolution_n like_o opium_n in_o watery_a menstruum_n its_o rank_a smell_n its_o titillate_v to_o venery_n its_o weight_n etc._n etc._n which_o be_v much_o the_o same_o with_o that_o of_o opium_n both_o sink_v in_o water_n etc._n etc._n 4._o by_o its_o great_a irritation_n to_o make_v water_n like_o cantharides_n bee_n pismire_n millepedes_n etc._n etc._n when_o it_o be_v take_v in_o a_o good_a quantity_n or_o often_o 5._o by_o its_o cause_v vomit_n in_o a_o very_a severe_a manner_n which_o it_o will_v not_o do_v without_o a_o very_a poignant_a volatile_a salt_n 6._o by_o its_o cause_v such_o violent_a itch_n in_o the_o skin_n especial_o if_o take_v in_o any_o quantity_n after_o it_o have_v pass_v all_o digestion_n and_o concoction_n and_o 7._o by_o its_o cause_v acrimonious_a sweat_v after_o it_o have_v pass_v those_o digestion_n and_o concoction_n 8._o by_o its_o cause_v a_o very_a pleasant_a sensation_n at_o stomach_n far_o above_o any_o flesh_n jelly_n or_o any_o animal_n nutriment_n 9_o by_o its_o offend_v the_o eye_n so_o much_o by_o its_o acrimony_n as_o mustard_n onion_n horse_n radish_n etc._n etc._n do_v 10._o by_o its_o very_a pungent_a and_o acrimonious_a taste_n above_o all_o flesh_n or_o fish_n 11._o by_o its_o very_a rank_n and_o vehement_a scent_n equal_a to_o if_o not_o exceed_v that_o of_o semen_n virile_a 12._o by_o its_o chemical_a analysis_n whereby_o it_o afford_v a_o very_a acrimonious_a volatile_a salt_n in_o great_a plenty_n which_o helmont_n wedelius_n and_o other_o do_v confirm_v therefore_o it_o be_v also_o past_a doubt_n that_o the_o volatile_a salt_n of_o opium_n be_v more_o active_a acrimonious_a and_o titillate_v than_o those_o in_o our_o membrane_n or_o in_o sem._n virile_a itself_o but_o see_v it_o be_v not_o volatile_a salt_n alone_o as_o be_v show_v which_o agree_v only_o with_o one_o of_o the_o active_a principle_n of_o our_o membrane_n and_o may_v be_v and_o be_v of_o itself_o too_o acrimonious_a and_o rude_a for_o the_o membrane_n without_o its_o be_v sweeten_v up_o and_o smooth_v into_o a_o more_o gentle_a and_o please_a agreeableness_n by_o oily_a part_n we_o must_v see_v whether_o it_o be_v not_o also_o oily_a or_o sulphureous_a and_o consequent_o a_o sal-volatile-oleosum_a agree_v in_o both_o the_o active_a principle_n of_o our_o membrane_n that_o it_o may_v thereby_o be_v the_o more_o delectable_a gentle_a and_o agreeable_a three_o it_o be_v very_o obvious_a and_o evident_a that_o opium_n be_v sulphureous_a 1._o because_o the_o juice_n of_o the_o poppy_n whereof_o it_o be_v make_v be_v of_o itself_o when_o it_o drop_n out_o of_o the_o incision_n milkwhite_a which_o colour_n in_o liquid_n especial_o the_o juice_n of_o plant_n proceed_v from_o sulphureous_a particle_n mix_v with_o water_n or_o phlegm_n as_o milk_n emulsion_n chyle_n cinnamon_n water_n and_o the_o tincture_n of_o all_o sulphureous_a thing_n drop_v into_o water_n do_v evince_n 2._o because_o it_o be_v inflammable_a for_o nothing_o be_v so_o but_o what_o be_v sulphureous_a 3._o because_o opium_n will_v soften_v with_o a_o dry_a warmth_n which_o all_o and_o only_o sulphureous_a thing_n will_v do_v as_o all_o rosin_n tallow_n pitch_v turpentine_n oil_n and_o such_o sulphureous_a thing_n 4._o because_o it_o be_v very_o bitter_a and_o that_o oleose_a particle_n be_v always_o as_o dr._n grow_v and_o silvius_n true_o say_v one_o ingredient_n of_o a_o bitter_a taste_n 5._o it_o be_v tawny_a colour_n do_v also_o as_o be_v say_v according_a to_o dr._n grow_v argue_v much_o sulphur_n 6._o it_o be_v hot_a taste_n prove_v the_o same_o for_o a_o proper_a hot_a taste_n be_v from_o sulphur_n as_o the_o bite_n or_o pungent_a be_v from_o volatile_a salt_n 7._o because_o of_o its_o pungent_a and_o strong_a smell_n which_o denote_v sulphur_n 8._o it_o be_v be_v so_o dissolvable_a as_o it_o be_v in_o spirit_n of_o wine_n brandy_n and_o other_o sulphureous_a menstruum_n prove_v the_o same_o 9_o it_o be_v dissolve_v quality_n argue_v that_o it_o have_v the_o same_o principle_n with_o our_o skin_n and_o flesh_n which_o be_v oleose_v as_o well_o as_o salino-volatile_a and_o that_o nothing_o be_v a_o complete_a dissolver_n but_o such_o as_o have_v both_o because_o agreeableness_n in_o principle_n be_v the_o basis_n of_o dissolution_n as_o you_o see_v in_o menstruum_n and_o the_o thing_n therein_o dissolve_v there_o be_v no_o good_a kind_a or_o complete_a dissolvent_a of_o our_o flesh_n etc._n etc._n but_o what_o participate_v of_o both_o because_o otherwise_o there_o will_v be_v a_o disagreement_n in_o one_o respect_n 10._o it_o appear_v by_o autopsie_n upon_o the_o chemical_a analysis_n of_o opium_n etc._n etc._n that_o it_o have_v a_o very_a considerable_a quantity_n of_o sulphur_n 11._o so_o if_o you_o only_o dissolve_v it_o in_o water_n you_o will_v find_v much_o sulphureous_a substance_n undissolved_a at_o the_o bottom_n 12._o all_o or_o most_o of_o the_o modern_a author_n attribute_v its_o operation_n to_o sulphur_n agree_v that_o it_o be_v well_o impregnate_v therewith_o therefore_o opium_n consist_v very_o much_o as_o to_o its_o active_a principle_n of_o a_o sal-volatile-sulphureum_a but_o still_o this_o do_v not_o complete_a a_o most_o agreeable_a sal-volatile-oleosum_a 1._o because_o it_o may_v be_v a_o sal-volatile-resinosum_a and_o yet_o be_v a_o sal-volatile-sulphureum_a 2._o if_o it_o be_v a_o sal-volatile-oleosum_a the_o oil_n and_o the_o volatile_a salt_n may_v be_v so_o disjoin_v as_o not_o to_o conspire_v and_o cooperate_v to_o please_v the_o membrane_n but_o act_n separately_z as_o oil_n and_o volatile_a salt_n give_v out_o of_o divers_a