part_n affect_v be_v debilitate_a and_o overcome_v by_o this_o deprave_a malign_a matter_n that_o it_o can_v exercise_v its_o transmutative_a and_o digestive_a power_n nor_o will_v this_o cancerous_a matter_n obey_v discussive_n by_o reason_n of_o the_o viscidity_n and_o grossness_n thereof_o wherefore_o hypocrates_n give_v sentence_n that_o such_o be_v not_o cure_v but_o by_o section_n or_o ustion_n and_o yet_o this_o be_v not_o to_o be_v do_v except_o the_o cancer_n be_v small_a and_o in_o such_o a_o part_n as_o will_v admit_v of_o amputation_n if_o cancer_n external_a be_v thus_o difficult_a to_o be_v manage_v although_o they_o appear_v to_o the_o eye_n and_o be_v subject_a to_o manual_a operation_n and_o tractation_n the_o internal_a must_v be_v great_a and_o more_o hazardous_a where_o they_o can_v be_v apply_v unto_o after_o this_o manner_n with_o convenient_a topical_a medicine_n therefore_o prevention_n in_o time_n be_v main_o to_o be_v endeavour_v when_o a_o tumour_n be_v generate_v lest_o it_o change_v into_o this_o dangerous_a condition_n for_o i_o find_v by_o the_o design_n of_o practiser_n in_o the_o remedy_n appoint_v that_o palliation_n be_v seek_v for_o the_o cure_n not_o hope_v for_o the_o grand_a intention_n to_o be_v prosecute_v for_o cure_n be_v to_o change_v the_o condition_n of_o the_o blood_n which_o do_v feed_v and_o supply_v this_o cancer_n so_o that_o the_o antecedent_n cause_n be_v take_v away_o the_o continent_n will_v then_o more_o likely_a abate_v and_o until_o that_o be_v do_v this_o can_v be_v expect_v the_o mean_v indicate_v for_o cure_n of_o these_o cancerous_a tumour_n be_v branch_v into_o three_o part_n dieatetic_n pharmaceutic_a and_o chirurgical_a but_o i_o shall_v not_o enlarge_v upon_o the_o indication_n for_o cure_n for_o that_o these_o case_n be_v so_o nice_a and_o difficult_a as_o not_o to_o be_v handle_v with_o general_n but_o from_o a_o collation_n of_o all_o the_o circumstance_n attend_v the_o patient_n which_o vary_v every_o particular_a case_n and_o so_o i_o pass_v from_o tumour_n to_o remark_n their_o usual_a commutation_n and_o transition_n into_o ulcer_n the_o next_o considerable_a in_o order_n to_o be_v treat_v of_o ulcer_n internal_a the_o latin_a word_n vlcus_fw-la be_v derive_v of_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d signify_v a_o disjunction_n of_o part_n or_o solution_n of_o continuity_n but_o to_o distinguish_v this_o from_o other_o solution_n of_o continuity_n a_o ulcer_n do_v yield_v a_o sanies_fw-la or_o purulent_a matter_n so_o that_o a_o wound_v come_v to_o digestion_n and_o afford_v pus_fw-la may_v then_o be_v call_v a_o ulcer_n and_o any_o part_n that_o be_v gaul_v raw_a and_o tender_a the_o cover_a membrane_n be_v fret_v and_o eat_v away_o by_o some_o sharp_a humour_n or_o other_o cause_n it_o style_v excoriation_n only_o until_o it_o produce_v corrupt_a matter_n and_o than_o it_o be_v proper_o call_v a_o ulcer_n thus_o internal_a part_n be_v sometime_o excoriate_v raw_a and_o painful_a but_o cicatrize_v or_o skin_v again_o before_o it_o arrive_v to_o the_o degree_n of_o a_o ulcer_n and_o thus_o it_o be_v most_o frequent_o in_o the_o urinary_a ducture_n or_o passage_n and_o sometime_o in_o the_o gut_n but_o such_o excoriation_n be_v not_o to_o be_v slight_v or_o neglect_v lest_o they_o beget_v vlceration_n as_o sometime_o it_o fall_v out_o so_o by_o external_a or_o outward_a ulcer_n which_o be_v manifest_a to_o the_o eye_n you_o may_v conceive_v of_o internal_a ulcer_n for_o they_o arise_v from_o the_o same_o cause_n and_o have_v the_o same_o accident_n but_o i_o shall_v not_o enlarge_v upon_o all_o the_o accidental_a difference_n that_o attend_v upon_o and_o distinguish_v external_a ulcer_n as_o not_o so_o pertinent_a and_o necessary_a to_o our_o subject_n in_o hand_n the_o essential_a and_o most_o considerable_a difference_n of_o ulcer_n do_v arise_v from_o their_o cause_n and_o from_o the_o part_n affect_v which_o bear_v the_o great_a sway_n in_o cure_v and_o from_o whence_o the_o chief_a indication_n be_v take_v for_o although_o in_o external_a ulcer_n other_o accidental_a difference_n may_v be_v observe_v and_o note_v yet_o in_o internal_a ulcer_n such_o difference_n can_v be_v regard_v as_o be_v obscure_v or_o hide_v so_o that_o whether_o they_o be_v broad_a or_o narrow_a deep_a or_o shallow_a fistulous_a or_o otherwise_o be_v hot_a positive_o to_o be_v say_v and_o if_o it_o be_v know_v institution_n or_o method_n of_o cure_n can_v not_o be_v so_o vary_v as_o external_a be_v capable_a of_o by_o reason_n these_o be_v subject_a to_o manual_a tractation_n the_o continent_n cause_v of_o vler_n be_v such_o matter_n as_o emane_n and_o flow_v from_o thence_o and_o that_o be_v of_o three_o sort_n ichor_n pus_fw-la and_o sordes_fw-la the_o first_o be_v a_o ichorous_a or_o sanious_a matter_n be_v thin_a indigested_a and_o watery_a or_o dilute_v bloody_a the_o second_o be_v a_o pus_fw-la or_o purulent_a matter_n of_o a_o bet_v consistence_n and_o concoct_v thick_a the_o three_o be_v a_o sordid_a foul_a matter_n more_o thick_a and_o glutinous_a the_o ichorous_a thin_a matter_n usual_o issue_v in_o the_o begin_n of_o ulcer_n and_o denote_v indigestion_n and_o also_o at_o any_o time_n afterward_o do_v declare_v the_o same_o that_o the_o ulcer_n be_v not_o in_o a_o good_a heal_a condition_n the_o pus_fw-la or_o purulent_a matter_n signify_v the_o ulcer_n to_o be_v in_o a_o better_a state_n of_o heal_a and_o if_o it_o be_v white_a and_o sweet_a these_o be_v good_a sign_n the_o sordid_a gross_a matter_n do_v intimate_v a_o preternatural_a heat_n of_o the_o part_n strong_o exsiccate_v but_o not_o heal_v for_o as_o much_o as_o this_o matter_n be_v foul_a and_o stink_a ulcer_n for_o their_o manner_n of_o generation_n and_o rise_v may_v be_v cause_v these_o four_o way_n by_o erosion_n by_o frication_n apostemation_n and_o contagion_n 1._o by_o erosion_n ulcer_n be_v beget_v in_o any_o part_n of_o the_o body_n when_o a_o sharp_a corrosive_a humour_n do_v excoriate_v and_o eat_v into_o the_o substance_n of_o any_o part_n and_o be_v thus_o injure_v be_v thereby_o pervert_v in_o its_o office_n and_o self-preservation_n convert_v that_o nutritious_a succus_fw-la which_o come_v for_o its_o supply_n into_o a_o ulcerous_a degenerate_a matter_n no_o way_n useful_a but_o to_o be_v excrete_v and_o void_v and_o thus_o a_o phthisis_fw-la a_o ulcer_n of_o the_o lung_n be_v sometime_o generate_v from_o a_o sharp_a serum_n invade_v that_o tender_a part_n and_o thus_o a_o dysentery_n be_v sometime_o beget_v be_v a_o ulceration_n of_o the_o gut_n from_o sharp_a excoriate_a humour_n and_o thus_o a_o ulceration_n in_o the_o meatus_fw-la penis_n be_v breed_v from_o a_o sharp_a erode_a gonorrhaea_n and_o a_o ulcer_n in_o the_o neck_n of_o the_o bladder_n may_v be_v plant_v there_o by_o a_o sharp_a gall_v urine_n 2._o by_o frication_n or_o attrition_n as_o when_o any_o hard_a bony_a or_o stony_a substance_n do_v fret_v raze_v and_o excoriate_v a_o part_n and_o thus_o a_o stone_n beget_v a_o ulcer_n in_o the_o kidney_n or_o bladder_n and_o sometime_o in_o other_o part_n of_o the_o body_n 3._o by_o apostemation_n as_o when_o any_o apostem_fw-la break_v and_o discharge_v its_o matter_n a_o ulcer_n be_v leave_v behind_o though_o the_o apostem_fw-la be_v go_v and_o thus_o be_v ulcer_n generate_v sometime_o in_o the_o ear_n from_o a_o precede_a apostem_fw-la in_o the_o aspera_fw-la arteria_fw-la after_o a_o angina_n or_o squinance_n in_o the_o breast_n after_o a_o pleurisy_n in_o the_o lung_n from_o a_o tumour_n suppurate_v there_o also_o in_o the_o liver_n spleen_n womb_n or_o other_o part_n apostemate_v 4._o by_o contagion_n or_o infection_n and_o thus_o woman_n whole_a privity_n be_v infect_v do_v communicate_v this_o virulency_n or_o venom_n and_o seize_v the_o genitals_o of_o their_o partner_n from_o whence_o venereal_a ulcer_n do_v arise_v and_o thus_o man_n whole_a seed_n be_v taint_v do_v infect_v sound_a woman_n and_o cause_v virulent_a ulcer_n in_o their_o privity_n which_o malignity_n not_o be_v well_o manage_v and_o master_v by_o skill_n and_o efficacious_a medicine_n it_o spread_v break_v forth_o and_o beget_v ulcer_n in_o many_o other_o part_n of_o the_o body_n as_o at_o large_a i_o have_v set_v forth_o in_o another_o tract_n entitle_v the_o mystery_n of_o the_o venereal_a lues_fw-la internal_a ulcer_n though_o they_o disappear_v yet_o be_v know_v to_o be_v by_o these_o sign_n first_o pain_n which_o be_v more_o or_o less_o according_a to_o the_o nature_n and_o sensibility_n of_o the_o part_n second_o from_o precede_a cause_n as_o inflammation_n or_o tumour_n precede_v who_o symptom_n be_v allay_v and_o cease_v yet_o pain_n remain_v three_o and_o manifest_o from_o excretion_n of_o ulcerous_a matter_n where_o there_o be_v any_o ducture_n or_o outlet_n for_o discharge_v by_o the_o intestine_n by_o the_o privity_n the_o nose_n ear_n or_o mouth_n but_o where_o there_o
their_o inconvenient_a and_o disturb_a object_n as_o the_o philosopher_n say_v excellens_fw-la sensibile_fw-la laedit_fw-la sen_fw-la sum_fw-la as_o the_o light_n of_o the_o sun_n or_o flame_n be_v troublesome_a to_o the_o eye_n and_o great_a noise_n as_o of_o a_o bell_n or_o gun_n if_o near_o especial_o sudden_a and_o unexpected_a do_v offend_v the_o ear_n and_o a_o strong_a or_o stink_a scent_n be_v offensive_a to_o the_o nose_n and_o a_o ungrateful_a taste_n as_o too_o salt_n too_o sour_a or_o bitter_a be_v unpleasant_a to_o the_o palate_n but_o pain_n affect_v the_o sense_n of_o feeling_n part_n therefore_o that_o be_v capable_a of_o pain_n be_v endow_v with_o the_o sense_n of_o feeling_n and_o those_o part_n be_v membranous_a that_o be_v they_o be_v invest_v with_o or_o line_v with_o some_o membrane_n by_o which_o the_o sense_n of_o feeling_n be_v communicate_v and_o hence_o the_o bone_n be_v capable_a of_o pain_n by_o the_o periosteum_n that_o membrane_n which_o cover_v they_o and_o this_o sense_n as_o it_o be_v more_o general_a extend_v through_o all_o part_n and_o more_o useful_a than_o the_o rest_n of_o the_o sense_n so_o the_o disturbance_n arise_v thence_o be_v more_o insufferable_a and_o grievous_a to_o be_v endure_v and_o better_o it_o be_v to_o want_v any_o other_o sense_n than_o this_o yea_o all_o for_o where_o feeling_n be_v depart_v the_o life_n be_v cease_v in_o that_o part_n this_o sense_n therefore_o be_v supreme_a the_o defection_n and_o disturbance_n thereof_o must_v be_v of_o great_a importance_n and_o concernment_n than_o the_o rest_n the_o other_o sense_n be_v confine_v to_o and_o exercise_v their_o function_n in_o one_o organ_n or_o part_n of_o the_o body_n the_o eye_n the_o ear_n etc._n etc._n but_o feeling_n be_v not_o restrain_v to_o so_o narrow_a a_o compass_n but_o be_v seat_v in_o all_o part_n of_o the_o body_n even_o in_o the_o organ_n of_o those_o other_o sense_n the_o great_a prerogative_n of_o this_o sense_n above_o the_o rest_n have_v no_o limit_n but_o reach_v through_o the_o whole_a body_n and_o exercise_v its_o power_n among_o the_o other_o sense_n and_o a_o inseparable_a consort_n with_o the_o life_n be_v worth_a inquire_v into_o the_o reason_n thereof_o if_o time_n will_v give_v leave_n for_o that_o diversion_n what_o pain_n be_v scarce_o any_o one_o but_o can_v tell_v and_o some_o by_o woeful_a experience_n whereby_o they_o will_v consent_v with_o the_o definition_n thereof_o dolour_n est_fw-la tristis_fw-la sensatio_fw-la in_o tactu_fw-la pain_n be_v a_o trouble_n arise_v in_o the_o sense_n of_o feeling_n but_o that_o which_o be_v so_o plain_o feel_v be_v not_o very_o easy_a to_o be_v understand_v from_o whence_o it_o do_v arise_v the_o cause_n of_o pain_n be_v as_o various_a as_o the_o object_n of_o the_o sense_n of_o feel_v for_o whatever_o object_n assault_v that_o sense_n violent_o or_o extreme_o as_o too_o hot_a cold_a hard_a sharp_a heavy_a etc._n etc._n be_v offensive_a to_o the_o organ_n of_o feel_v and_o do_v raise_v pain_n concern_v the_o approximate_a cause_n of_o pain_n there_o be_v several_a opinion_n i_o wave_v the_o more_o extravagant_a and_o improbable_a and_o shall_v recite_v those_o in_o which_o the_o most_o philosopher_n and_o eminent_a physician_n do_v consent_n and_o pitch_n upon_o as_o most_o agreeable_a to_o reason_n one_o party_n assert_n that_o a_o sudden_a and_o violent_a mutation_n of_o the_o active_a quality_n or_o the_o tactil_a quality_n sudden_o and_o violent_o act_v upon_o the_o sense_n of_o feeling_n be_v the_o approximate_a cause_n of_o pain_n the_o other_o party_n determine_v that_o solutio_fw-la continui_fw-la a_o solution_n or_o disjunction_n of_o continuity_n be_v the_o immediate_a cause_n of_o all_o pain_n the_o three_o opinion_n join_v these_o two_o together_o and_o will_v have_v pain_n to_o arise_v from_o they_o both_o according_a to_o the_o definition_n of_o plato_n est_fw-la itaque_fw-la dolour_n tristis_fw-la in_o sensu_fw-la tactûs_fw-la affectio_fw-la à _fw-la membri_fw-la intemperie_n &_o continuitatis_fw-la divortio_fw-la subitò_fw-la facta_fw-la and_o hippoc._n before_o he_o teach_v the_o same_o doctrine_n quae_fw-la naturam_fw-la inquit_fw-la mutant_fw-la ac_fw-la corrumpunt_fw-la dolores_fw-la excitant_fw-la to_o which_o galen_n do_v subscribe_v now_o to_o comment_v a_o little_a upon_o these_o different_a judgement_n i_o can_v but_o observe_v and_o do_v own_o that_o there_o be_v something_o of_o probability_n and_o reason_n in_o these_o several_a sentiment_n but_o not_o a_o full_a satisfaction_n to_o the_o matter_n query_v nor_o the_o whole_a truth_n right_o state_v and_o for_o this_o reason_n i_o be_o the_o more_o nice_a and_o strict_a in_o this_o inquiry_n because_o from_o hence_o the_o nature_n of_o anodynes_n or_o assuager_n of_o pain_n be_v discover_v and_o this_o be_v the_o groundwork_n upon_o which_o they_o be_v form_v and_o right_o adapt_v i_o allow_v that_o unity_n be_v the_o perfection_n of_o body_n and_o be_v necessary_a to_o perfect_a sanity_n disjunction_n or_o separation_n dissolve_v the_o harmony_n and_o lead_v or_o be_v the_o progress_n to_o destruction_n for_o whatever_o tend_v to_o disjoin_v or_o make_v a_o separation_n of_o part_n do_v threaten_v to_o ruin_v the_o whole_a and_o true_a it_o be_v that_o the_o active_a quality_n or_o tactil_a object_n do_v cause_n pain_n as_o they_o do_v make_v their_o impulsion_n violent_o upon_o the_o organ_n of_o feel_v which_o when_o they_o do_v it_o moderate_o placid_o and_o amicable_o they_o cause_v pleasure_n or_o no_o pain_n but_o whether_o the_o impetuous_a and_o vehement_a act_n of_o those_o agent_n raise_v pain_n do_v always_o cause_v a_o solution_n of_o continuity_n approximate_o and_o immediate_o be_v much_o to_o be_v doubt_v i_o yield_v that_o the_o vehemency_n of_o these_o tactil_a object_n may_v procure_v a_o solution_n of_o continuity_n sometime_o as_o we_o see_v from_o pain_n that_o imposthume_n ulcer_n gangrene_n and_o mortification_n do_v follow_v but_o these_o be_v not_o inseparable_a and_o necessary_a consequent_n for_o they_o happen_v but_o sometime_o pain_n may_v continue_v for_o a_o time_n cease_v again_o and_o no_o breach_n of_o continuity_n remain_v aâ—_n a_o effect_n thereof_o to_o which_o our_o adversary_n have_v this_o evasion_n by_o way_n of_o reply_n that_o pain_n be_v cause_v à _fw-la continui_fw-la solutione_n non_fw-la à _fw-la soluta_fw-la unitate_fw-la which_o as_o i_o conceive_v the_o meaning_n be_v as_o much_o as_o to_o say_v solution_n of_o continuity_n in_o fieri_fw-la be_v sufficient_a though_o it_o be_v not_o in_o facto_fw-la esse_fw-la but_o to_o pass_v over_o this_o sophistry_n as_o not_o worth_a the_o expense_n of_o time_n to_o lay_v it_o open_a and_o if_o we_o make_v appear_v that_o the_o whole_a matter_n or_o controversy_n be_v bottom_v upon_o this_o error_n mistake_v the_o cause_n for_o the_o effect_n and_o the_o effect_n for_o the_o cause_n cujus_fw-la contrarium_fw-la then_o the_o plead_n of_o our_o antagonist_n will_v be_v put_v to_o silence_n as_o absurd_a the_o doctrine_n lay_v aside_o and_o practice_n ground_v upon_o better_a principle_n they_o affirm_v solution_n of_o continuity_n to_o be_v the_o approximate_a cause_n of_o pain_n the_o contrary_a whereof_o we_o will_v set_v forth_o and_o prove_v that_o pain_n be_v the_o cause_n of_o solution_n of_o continuity_n and_o here_o we_o must_v first_o distinguish_v between_o violent_a external_a agent_n as_o sword_n staff_z bullet_n fire_n etc._n etc._n cause_v wound_n contusion_n fracture_n combustion_n etc._n etc._n and_o internal_a cause_n gradual_o arise_v in_o the_o body_n as_o product_n of_o a_o degenerate_a state_n in_o the_o first_o case_n solution_n of_o continuity_n cause_v pain_n as_o when_o the_o wound_n be_v give_v pain_n follow_v as_o a_o effect_n so_o likewise_o upon_o a_o sudden_a fracture_n or_o rapture_n in_o the_o latter_a pain_n precede_v as_o the_o approximate_a cause_n solution_n of_o continuity_n come_v after_o as_o the_o product_n or_o consequent_a for_o example_n some_o indigested_a or_o degenerate_a matter_n lodge_v or_o fix_v in_o this_o or_o that_o part_n of_o the_o body_n nature_n not_o able_a to_o subdue_v or_o transmit_v it_o away_o this_o like_a a_o thorn_n irritate_v and_o provoke_v the_o vital_a principle_n to_o a_o disquietness_n and_o disturbance_n which_o be_v pain_n this_o pain_n draw_v a_o confluence_n of_o humour_n to_o the_o part_n grieve_v and_o increase_v the_o first_o offend_v matter_n cause_v inflammation_n and_o tumour_n this_o apostemate_n and_o then_o break_v forth_o into_o a_o ulcer_n observe_v the_o series_n first_o here_o be_v peccant_a matter_n as_o the_o occasional_a cause_n raise_v pain_n this_o pain_n attract_v humour_n from_o other_o part_n which_o be_v transplant_v out_o of_o their_o proper_a place_n they_o degenerate_a corrupt_a and_o then_o produce_v a_o imposthume_n and_o ulcer_n thus_o you_o see_v pain_n go_v before_o solution_n of_o continuity_n follow_v after_o and_o therefore_o it_o be_v plain_a as_o in_o
this_o so_o in_o all_o other_o case_n where_o separation_n of_o unity_n do_v happen_v from_o a_o internal_a cause_n arise_v in_o the_o body_n that_o it_o be_v the_o consequent_a of_o pain_n and_o not_o as_o those_o learned_a man_n will_v have_v it_o the_o approximate_a cause_n of_o pain_n to_o illustrate_v this_o truth_n a_o little_a far_o and_o that_o you_o may_v the_o better_o understand_v and_o have_v a_o clear_a satisfaction_n herein_o practice_n depend_v upon_o it_o i_o mean_v the_o allay_n or_o remove_v of_o pain_n consider_v and_o know_v that_o the_o sense_n of_o feel_v be_v spread_v through_o the_o whole_a body_n be_v as_o the_o last_o or_o inmost_a cover_n that_o do_v inwrap_v or_o enfold_v the_o life_n and_o be_v as_o it_o be_v the_o watch_n or_o guard_v upon_o the_o confine_n thereof_o now_o any_o thing_n that_o do_v stir_v up_o feel_v that_o thus_o near_o and_o intimate_o approach_v the_o life_n if_o it_o exceed_v the_o bound_n of_o moderation_n and_o be_v violent_a if_o it_o be_v any_o way_n unnatural_a or_o injurious_a it_o raise_v a_o disturbance_n in_o the_o vital_a principle_n of_o that_o part_n which_o be_v pain_n so_o that_o the_o assault_n be_v first_o make_v upon_o the_o life_n which_o govern_v and_o preserve_v unity_n and_o continuity_n of_o part_n but_o that_o vital_a principle_n be_v fret_v distract_a and_o put_v by_o its_o placid_n regular_a oeconomy_n and_o government_n the_o organ_n perish_v as_o the_o life_n of_o the_o part_n decay_v or_o be_v out_o of_o course_n be_v then_o unable_a to_o protect_v and_o preserve_v it_o from_o hence_o i_o be_o persuade_v to_o believe_v and_o must_v assert_v that_o the_o approximate_a cause_n of_o pain_n be_v every_o thing_n that_o do_v intimate_o and_o approximate_o affect_v and_o disgust_v the_o vital_a principle_n in_o every_o part_n pain_v which_o pain_n be_v the_o estuation_n anguish_n and_o fury_n of_o the_o life_n or_o vital_a principle_n which_o do_v dolere_fw-la be_v exasperate_v and_o provoke_v by_o those_o cause_n and_o if_o solution_n of_o continuity_n do_v happen_v upon_o this_o disturbance_n it_o be_v wrought_v and_o cause_v by_o the_o exorbitance_n and_o enormity_n of_o the_o vital_a principle_n desert_v or_o be_v put_v by_o the_o charge_n and_o due_a management_n of_o the_o part_n moreover_o pain_n sometime_o continue_v long_o by_o interval_n and_o remission_n to_o molest_v a_o part_n and_o no_o separation_n of_o unity_n to_o be_v cause_v thereby_o although_o it_o be_v a_o interruption_n and_o breach_n of_o harmony_n so_o that_o this_o ira_fw-la sive_fw-la dolour_n this_o pain_n of_o the_o vital_a principle_n do_v not_o always_o arise_v to_o the_o height_n of_o produce_v discontinuity_n and_o be_v so_o far_o from_o be_v the_o approximate_a cause_n of_o all_o pain_n that_o many_o time_n it_o never_o happen_v either_o before_o or_o after_o pain_n to_o be_v a_o cause_n or_o a_o effect_n now_o what_o this_o vital_a principle_n be_v reside_v in_o and_o govern_v every_o part_n in_o their_o several_a function_n of_o vitality_n whether_o it_o be_v anima_fw-la or_o archaeus_n according_a to_o helmont_n doctrine_n or_o spiritus_fw-la impetum_fw-la faciens_fw-la according_a to_o hypocrates_n i_o shall_v not_o enter_v into_o the_o controversy_n because_o it_o will_v require_v a_o large_a discourse_n or_o rather_o a_o peculiar_a tract_n to_o determine_v this_o problem_n and_o clear_v up_o the_o truth_n of_o our_o novel_a opinion_n disintangle_v it_o from_o the_o objection_n and_o prejudice_n of_o ancient_a receive_v doctrine_n which_o will_v disjoin_v and_o delay_v our_o matter_n chief_o intend_v therefore_o i_o forbear_v the_o digression_n and_o proceed_v pain_n be_v various_a or_o do_v affect_v the_o sense_n in_o a_o different_a manner_n and_o this_o either_o from_o the_o nature_n of_o the_o part_n grieve_v or_o from_o the_o variety_n of_o cause_n or_o both_o now_o the_o nature_n and_o condition_n of_o part_n be_v different_a and_o various_a these_o ten_o several_a way_n or_o may_v be_v reduce_v to_o these_o head_n ducture_n figure_n situation_n composition_n beginning_n progress_n substance_n temperature_n number_n and_o office_n and_o as_o part_n be_v vary_v by_o these_o difference_n so_o pain_n thereby_o be_v make_v various_a and_o not_o only_a pain_n but_o also_o all_o other_o symptom_n and_o disease_n have_v a_o specification_n from_o hence_o pain_n sometime_o be_v obtuse_a or_o heavy_a as_o if_o a_o weight_n be_v press_v upon_o the_o part_n pain_v as_o when_o the_o parenchyma_n of_o the_o liver_n spleen_n lung_n or_o kidney_n be_v grieve_v and_o this_o by_o reason_n they_o hang_v or_o depend_v on_o ligament_n and_o membrane_n pain_n sometime_o be_v acute_a sharp_a and_o pung_a as_o if_o the_o part_n be_v perforate_v or_o prick_v with_o a_o needle_n as_o in_o a_o pleurisy_n and_o this_o be_v cause_v from_o a_o thin_a acrid_a or_o acrimonious_a humour_n penetrate_v the_o pleura_fw-la for_o nothing_o but_o what_o be_v subtle_a and_o acute_a can_v procure_v this_o or_o the_o like_a puncture_n and_o invade_v the_o dense_a substance_n of_o a_o membrane_n pain_n sometime_o be_v with_o pulsation_n that_o be_v a_o beat_a pain_n like_o to_o the_o motion_n of_o the_o pulse_n and_o this_o pain_n happen_v common_o upon_o a_o inflammation_n and_o also_o where_o a_o artery_n be_v seat_v in_o the_o part_n for_o where_o there_o be_v no_o artery_n there_o be_v no_o pulsation_n it_o be_v the_o office_n of_o this_o vessel_n only_o to_o make_v a_o pulse_n from_o hence_o galen_n 2._o de_fw-fr loc_fw-la affect_v 3._o take_v notice_n that_o upon_o a_o inflammation_n of_o the_o lung_n or_o the_o pleura_fw-la there_o be_v no_o pulsation_n or_o beat_v pain_n because_o there_o be_v no_o artery_n in_o the_o part_n pain_n sometime_o be_v mordacious_a or_o bite_a from_o sharp_a humour_n vellicate_v the_o sensible_a part_n pain_n sometime_o be_v frangitive_a as_o if_o grind_v or_o bruise_v and_o this_o be_v proper_a only_o to_o the_o bone_n or_o rather_o the_o periosteum_n that_o cover_v the_o bone_n by_o which_o membrane_n the_o bone_n be_v make_v sensible_a and_o the_o pain_n lie_v deep_a pain_n sometime_o be_v tensive_a or_o stretch_v and_o this_o happen_v from_o a_o repletion_n or_o fullness_n of_o some_o humour_n wind_n or_o vapour_n fill_v and_o extend_v the_o part_n if_o this_o stretch_a pain_n be_v cum_fw-la gravitate_fw-la &_o pondere_fw-la with_o heaviness_n or_o weight_n than_o you_o may_v conclude_v it_o be_v humoral_a or_o something_o of_o more_o solid_a substance_n but_o if_o the_o extensive_a pain_n be_v without_o weight_n than_o it_o signify_v wind_n or_o vapour_n as_o very_o often_o such_o be_v colic_n pain_n from_o a_o collection_n of_o wind_n between_o the_o tunicle_n of_o the_o gut_n pain_n sometime_o be_v convulsive_a and_o this_o be_v proper_a to_o the_o nerve_n and_o tendon_n because_o the_o nervous_a filament_n be_v so_o unite_v that_o they_o can_v be_v tear_v but_o be_v contract_v to_o their_o original_n pain_n sometime_o be_v lacerate_v or_o tear_v and_o this_o be_v proper_a to_o the_o flesh_n because_o the_o flesh_n have_v fibres_n and_o small_a nerve_n not_o so_o unite_v as_o the_o membrane_n and_o therefore_o à _fw-la causa_fw-la solvente_fw-la continuum_fw-la be_v easy_o lacerate_v and_o thus_o much_o for_o the_o various_a kind_n or_o different_a sort_n of_o pain_n next_o the_o situation_n or_o extension_n and_o the_o duration_n be_v to_o be_v regard_v pain_n be_v either_o universal_a affect_v the_o whole_a body_n from_o some_o general_a cause_n as_o in_o fever_n ague_n etc._n etc._n or_o else_o pain_n be_v seat_v in_o some_o particular_a region_n or_o part_n of_o the_o body_n as_o the_o head_n breast_n stomach_n belly_n etc._n etc._n pain_n sometime_o be_v more_o outward_a ot_fw-mi external_a upon_o the_o superficies_n of_o the_o body_n who_o seat_n be_v more_o easy_o discover_v and_o know_v lay_v hand_n upon_o the_o place_n by_o the_o patient_n direction_n sometime_o pain_n be_v internal_a and_o deep_a with_o difficulty_n to_o be_v certain_o determine_v which_o part_n be_v grieve_v and_o require_v good_a anatomical_a judgement_n to_o assign_v the_o part_n or_o member_n from_o hence_o pain_n some_o may_v be_v say_v to_o be_v manifest_a other_o abstruse_a as_o also_o from_o their_o cause_n evident_a and_o latent_fw-la pain_n some_o be_v constant_a as_o to_o place_v or_o fix_v other_o erratic_a or_o shift_a from_o one_o place_n to_o another_o pain_n some_o be_v constant_a as_o to_o time_n or_o continual_a other_o intermit_a and_o by_o interval_n have_v cessation_n for_o a_o time_n and_o return_v again_o in_o all_o pain_n there_o ought_v to_o be_v consider_v these_o four_o thing_n the_o greatness_n the_o kind_a the_o property_n the_o place_n greatness_n and_o vehemency_n of_o pain_n do_v arise_v from_o the_o greatness_n of_o the_o offend_a cause_n and_o the_o sensibility_n call_v tenderness_n of_o the_o part_n all_o pain_n
common_o call_v stitch_n pain_n be_v incident_a to_o these_o muscle_n from_o external_a injury_n as_o contusion_n and_o impression_n of_o cold_a or_o else_o internal_a cause_n and_o these_o be_v either_o by_o defluxion_n of_o humour_n that_o may_v flow_v in_o as_o most_o frequent_o from_o a_o abound_a serosity_n be_v thin_a sharp_a and_o extravasated_a fall_v in_o among_o these_o muscle_n or_o else_o by_o congestion_n matter_n be_v accumulate_v which_o nature_n not_o be_v able_a to_o discharge_v lie_v there_o as_o a_o burden_n impede_v the_o muscular_a motion_n and_o cause_v pain_n sometime_o from_o flatulency_n and_o wind_n get_v into_o the_o interstitia_fw-la of_o the_o muscle_n thereby_o cause_v intercurrent_a and_o fleet_a pain_n and_o for_o remedy_n in_o such_o case_n fomentation_n and_o hot_a bag_n apply_v be_v advantageous_a evacuation_n be_v premit_v according_a to_o the_o condition_n of_o the_o body_n require_v we_o come_v now_o to_o consider_v of_o pleurisy_n or_o pain_n in_o the_o pleura_fw-la that_o inward_a membrane_n that_o do_v invest_v or_o line_v the_o breast_n a_o disease_n very_o eminent_a and_o frequent_o occur_v that_o both_o hippoc._n and_o galen_n often_o mention_v it_o by_o way_n of_o example_n these_o pain_n be_v acute_a and_o sharp_a like_o puncture_n and_o have_v no_o constant_a place_n but_o in_o some_o person_n they_o seize_v the_o right_a side_n in_o other_o the_o left_a in_o some_o the_o pain_n be_v high_a in_o other_o low_o towards_o the_o hypochonder_n sometime_o more_o backward_o and_o sometime_o forward_o and_o although_o chief_o and_o more_o manifest_o the_o pain_n be_v here_o or_o there_o to_o be_v point_v at_o yet_o the_o whole_a membrane_n by_o reason_n of_o continuity_n be_v thereby_o affect_v and_o the_o part_n adjacent_a do_v suffer_v by_o consent_n from_o whence_o various_a symptom_n as_o concomitant_n and_o attendant_n do_v inseparable_o accompany_v and_o consort_v with_o this_o pleuritic_n pain_n hence_o it_o be_v that_o difficult_a and_o short_a breathe_n be_v constant_o annex_v to_o it_o and_o this_o because_o the_o part_n for_o respiration_n be_v hereby_o impede_v and_o have_v not_o their_o due_a motion_n and_o liberty_n of_o extension_n but_o be_v restrain_v and_o curb_v which_o be_v do_v in_o favour_n to_o avoid_v compress_v the_o grieve_a part_n otherwise_o will_v exasperate_v and_o increase_v the_o pain_n and_o therefore_o the_o sick_a fetch_v their_o breath_n short_a and_o quick_a because_o they_o can_v take_v it_o full_o and_o large_o and_o do_v repeat_v it_o the_o often_o by_o way_n of_o recompense_n to_o this_o and_o by_o consent_n of_o part_n be_v adjoin_v a_o short_a and_o dry_a cough_n which_o irritate_v and_o provoke_v the_o pain_n by_o move_v and_o strain_v those_o part_n and_o therefore_o be_v very_o troublesome_a and_o grievous_a to_o the_o patient_n here_o also_o a_o continual_a acute_a fever_n do_v necessary_o follow_v as_o inseparable_a for_o the_o archaeus_n or_o vital_a principle_n be_v invade_v in_o those_o part_n by_o something_o hostile_a do_v therefore_o insurge_v become_v enrage_v grow_v hot_a and_o fiery_a raise_v a_o burn_a distemper_n throughout_o the_o body_n to_o these_o we_o may_v add_v another_o constant_a character_n namely_o a_o hard_a swift_a but_o small_a pulse_n and_o these_o be_v the_o pathognomonical_a signal_n that_o be_v always_o attend_v upon_o and_o do_v distinguish_v pleurisy_n from_o other_o disease_n of_o adjacency_n or_o affinity_n and_o likeness_n with_o they_o for_o when_o pain_n fall_v in_o among_o the_o intercostal_a muscle_n although_o there_o may_v be_v some_o puncture_n or_o pricking_n because_o of_o the_o membrane_n there_o yet_o not_o so_o great_a the_o fever_n not_o so_o high_a nor_o the_o breath_n so_o short_a nor_o the_o cough_n so_o troublesome_a if_o any_o if_o the_o lung_n be_v inflame_v only_o the_o pain_n be_v but_o little_a not_o pung_v but_o obtuse_a not_o in_o the_o circumference_n or_o side_n but_o in_o the_o cavity_n or_o middle_n of_o the_o breast_n yet_o the_o difficulty_n of_o breathe_v be_v great_a here_o than_o in_o pleurisy_n from_o angustness_n that_o seize_v the_o part_n of_o respiration_n pleurisy_n differ_v from_o inflammation_n of_o the_o diaphragma_n because_o in_o this_o there_o be_v no_o pain_n in_o the_o side_n but_o only_o at_o the_o end_n of_o the_o short_a rib_n and_o the_o upper_a part_n of_o the_o belly_n be_v extend_v and_o with_o it_o a_o delirium_fw-la pleurisy_n also_o be_v distinguish_v from_o inflammation_n of_o the_o liver_n in_o the_o seat_n or_o place_n of_o pain_n which_o always_o be_v in_o the_o right_a side_n under_o the_o short_a rib_n the_o pain_n not_o pung_v but_o heavy_a and_o obtuse_a the_o cough_n less_o difficulty_n of_o breathe_v less_o but_o the_o urine_n higher-coloured_n or_o tinged_a red_a and_o now_o i_o see_v the_o reason_n though_o very_o weak_a why_o some_o author_n have_v distinguish_v pleurisy_n or_o difference_v they_o into_o legitimate_a and_o spurious_a which_o indeed_o be_v a_o division_n of_o pleurisy_n into_o pleurisy_n and_o no_o pleurisy_n for_o i_o account_v no_o disease_n to_o challenge_v that_o denomination_n but_o such_o as_o have_v their_o foundation_n in_o the_o pleura_fw-la else_o by_o the_o same_o reason_n all_o disease_n may_v admit_v of_o the_o same_o distinction_n of_o legitimate_a and_o spurious_a for_o as_o much_o as_o every_o disease_n have_v some_o symptom_n which_o be_v common_a to_o other_o disease_n that_o may_v give_v they_o some_o resemblance_n or_o affinity_n with_o each_o other_o or_o be_v affect_v by_o consent_n from_o another_o but_o i_o pass_v it_o over_o and_o come_v to_o examine_v the_o cause_n from_o whence_o pleuritic_n pain_n do_v arise_v these_o cause_n be_v external_a and_o internal_a external_n cause_n be_v such_o as_o remote_o prepare_v and_o dispose_v the_o body_n to_o a_o likely_a capacity_n of_o reception_n or_o aptness_n to_o this_o disease_n lay_v the_o foundation_n for_o internal_a cause_n and_o they_o do_v arise_v out_o of_o or_o from_o the_o irregular_a unfit_a or_o improper_a use_n of_o the_o diaetetic_n which_o lead_v to_o a_o morbific_a or_o unsound_a state_n for_o example_n violent_a exercise_n or_o otherwise_o raise_v great_a heat_n in_o the_o body_n and_o open_v the_o pore_n by_o neglect_n upon_o it_o as_o not_o to_o preserve_v that_o warmth_n for_o some_o time_n and_o suffer_v it_o gradual_o to_o abate_v and_o go_v off_o by_o keep_v on_o clothes_n and_o forbear_v cool_a drink_n this_o may_v introduce_v a_o pleurisy_n so_o likewise_o in_o the_o heat_n of_o summer_n to_o throw_v off_o clothes_n and_o be_v expose_v to_o the_o wind_n at_o a_o casement_n or_o the_o cool_a air_n in_o the_o evening_n to_o overheat_v the_o body_n with_o strong_a liquor_n and_o sudden_o endeavour_v to_o cool_v it_o again_o with_o small_a beer_n may_v effect_v the_o like_a cold_a north-wind_n after_o southerly_a and_o hot_a weather_n do_v alter_v the_o texture_n of_o the_o blood_n and_o be_v previous_a to_o pleuritic_n or_o similar_v pain_n but_o here_o you_o must_v take_v notice_n and_o know_v that_o quicquid_fw-la recipitur_fw-la recipitur_fw-la per_fw-la modum_fw-la recipientis_fw-la all_o body_n be_v not_o alike_o nor_o equal_o dispose_v for_o reception_n for_o in_o some_o these_o cause_n produce_v pleurisy_n in_o other_o angina_n in_o some_o dysentery_n in_o other_o arthritic_n pain_n etc._n etc._n according_a to_o the_o aptitude_n and_o disposition_n of_o body_n in_o fabrication_n or_o organization_n and_o peculiar_a property_n have_v the_o same_o general_a external_a cause_n various_a and_o divers_a effect_n be_v determine_v and_o specificate_v by_o different_a state_n of_o body_n more_o liable_a and_o apt_a to_o this_o or_o that_o disease_n rather_o than_o another_o hence_o it_o be_v that_o external_a cause_n as_o diaetetic_n error_n have_v heterogeneous_a effect_n and_o procure_v dissimilar_v disease_n according_a to_o various_a constitution_n purity_n and_o impurity_n stability_n or_o debility_n concur_v with_o or_o resist_v their_o influence_n which_o consideration_n bring_v i_o direct_o to_o the_o next_o stage_n be_v the_o latter_a part_n of_o the_o precede_a division_n internal_a cause_n be_v antecedent_n or_o conjunct_a antecedent_n as_o plethory_n be_v fullness_n of_o blood_n or_o cacochymy_n a_o deprave_a or_o degenerate_a blood_n both_o which_o be_v previous_a state_n or_o condition_n of_o body_n dispose_v or_o render_v more_o liable_a to_o this_o disease_n for_o the_o great_a vessel_n be_v full_a and_o distend_v upon_o any_o effervescence_n and_o superfermentation_n of_o the_o blood_n this_o impetuous_o like_o a_o torrent_n be_v impel_v into_o the_o small_a pipe_n as_o those_o of_o the_o pleura_fw-la where_o not_o have_v a_o free_a passage_n it_o do_v cause_n pain_n by_o distension_n and_o inflammation_n now_o this_o plenitude_n be_v bring_v on_o or_o aggravate_v and_o increase_v sometime_o by_o a_o suppression_n of_o some_o accustom_a evacuation_n as_o those_o that_o be_v wont_a
pervious_a caruncle_n or_o glandulous_a substance_n through_o which_o the_o serum_n be_v strain_v and_o thus_o the_o water_n be_v transmit_v by_o percolation_n the_o vessel_n bring_v into_o the_o reins_o be_v the_o emulgent_a artery_n and_o these_o draw_v a_o serum_n from_o the_o great_a trunk_n of_o the_o aorta_fw-la arteria_fw-la and_o import_v it_o into_o the_o kidney_n the_o emulgent_a vein_n from_o the_o vena_fw-la cava_fw-la be_v think_v by_o the_o ancient_n to_o be_v for_o the_o same_o purpose_n but_o latter_a discovery_n contradict_v it_o they_o also_o receive_v from_o the_o lacteal_v vein_n the_o thin_a and_o more_o watery_a part_n of_o the_o chyle_n be_v a_o expedite_a and_o short_a way_n hence_o it_o be_v the_o urine_n be_v pale_a or_o whitish_a when_o the_o kidney_n be_v not_o strong_a enough_o to_o give_v this_o milky_a humour_n the_o urinary_a digestion_n or_o when_o drink_n be_v too_o plentiful_o pour_v in_o and_o force_v through_o before_o its_o due_a time_n therefore_o great_a drinker_n common_o piss_v a_o pale_a water_n there_o be_v also_o nerve_n insert_v into_o the_o kidney_n from_o a_o branch_n of_o the_o six_o pair_n which_o also_o serve_v the_o ventricle_n hence_o it_o be_v that_o the_o stomach_n be_v draw_v into_o consent_n by_o loss_n of_o appetite_n nauseat_v and_o vomit_v when_o the_o kidney_n be_v pain_v as_o in_o a_o fit_a of_o the_o stone_n it_o be_v manifest_a by_o these_o nerve_n the_o kidney_n do_v suffer_v not_o only_o a_o heaviness_n but_o sometime_o very_o acute_a pain_n vessel_n carry_v the_o urine_n out_o of_o the_o kidney_n be_v the_o vreter_n one_o belong_v to_o each_o kidney_n and_o they_o pass_v from_o hence_o down_o by_o the_o loin_n between_o the_o two_o membrane_n of_o the_o peritonaeum_fw-la and_o be_v insert_v into_o the_o bladder_n to_o convey_v the_o urine_n thither_o the_o length_n of_o these_o urinary_a ducture_n be_v about_o a_o span_n the_o cavity_n or_o hollow_a like_o a_o straw_n but_o capable_a of_o enlargement_n to_o the_o bigness_n of_o a_o finger_n as_o by_o a_o stone_n come_v down_o though_o with_o extreme_a pain_n by_o reason_n they_o be_v membranous_a and_o nervous_a exquisite_o sensible_a and_o therefore_o upon_o any_o obstruction_n be_v high_o urge_v to_o expulsion_n especial_o by_o a_o solid_a sharp_a or_o rugged_a body_n as_o stone_n or_o gravel_n hereby_o you_o may_v understand_v the_o office_n and_o use_n of_o these_o part_n that_o be_v to_o drain_v the_o body_n from_o a_o superfluous_a saline_a and_o tartarous_a serosity_n and_o this_o aught_o daily_a and_o dull_o to_o be_v perform_v but_o this_o serosity_n be_v not_o all_o discharge_v this_o way_n by_o the_o reins_o but_o some_o pass_v off_o by_o insensible_a transpiration_n and_o some_o by_o manifest_a sweat_v but_o the_o great_a part_n by_o the_o kidney_n and_o from_o hence_o it_o appear_v that_o the_o urine_n be_v partly_o a_o excrement_n of_o the_o first_o digestion_n in_o respect_n of_o the_o aquosity_n draw_v from_o the_o lacteal_n juice_n and_o partly_o of_o the_o second_o in_o respect_n of_o the_o serum_n sanguinis_fw-la exhaust_v from_o the_o blood_n by_o the_o emulgent_a artery_n and_o here_o you_o may_v observe_v that_o by_o a_o certain_a digestion_n or_o elaboration_n in_o the_o kidney_n these_o serosity_n be_v transmute_v into_o urine_n and_o then_o carry_v a_o odour_n or_o scent_n with_o it_o much_o different_a from_o what_o it_o be_v before_o and_o the_o like_a we_o may_v observe_v in_o other_o creature_n that_o their_o urine_n have_v peculiar_a smell_n which_o argue_v a_o digestive_a transmutation_n but_o although_o nature_n intend_v and_o endeavour_v this_o work_n constant_o yet_o there_o be_v many_o casualty_n and_o impediment_n to_o disturb_v these_o part_n and_o frustrate_v in_o some_o measure_n the_o designment_n of_o nature_n the_o error_n and_o fail_n herein_o we_o shall_v recite_v but_o those_o chief_o that_o be_v accompany_v with_o or_o produce_v pain_n we_o shall_v discourse_v of_o with_o brevity_n the_o general_a and_o most_o frequent_a symptom_n that_o manifest_o afflict_v or_o incommode_v the_o reins_o be_v pain_n and_o weakness_n or_o tenderness_n about_o those_o part_n disease_n plant_v there_o from_o whence_o those_o pain_n or_o weakness_n do_v arise_v and_o depend_v be_v intemperate_a heat_n imbecility_n and_o a_o decline_a state_n consumptive_a diminution_n and_o waste_v inflammation_n scirrhous_n tumour_n angustness_n and_o obstruction_n of_o the_o cavity_n and_o ducture_n apertion_n of_o the_o vessel_n apostem_n ulcer_n some_o there_o be_v who_o pain_n be_v hot_a and_o molest_a not_o by_o a_o natural_a constitution_n but_o acquire_v by_o time_n and_o evil_a custom_n or_o accident_n happen_v to_o those_o part_n and_o this_o beget_v a_o tenderness_n there_o and_o it_o be_v painful_a to_o lie_v on_o the_o back_n the_o urine_n most_o frequent_o be_v hot_a or_o high-coloured_n sometime_o sharp_a and_o then_o apt_a to_o make_v water_n often_o prone_a to_o venery_n at_o least_o the_o constitution_n of_o those_o part_n do_v dispose_v that_o way_n cause_n introduce_v this_o distemper_n be_v too_o frequent_a use_n of_o wine_n strong_a drink_n and_o hot_a spice_n much_o ride_v lie_v on_o the_o back_n and_o soft_a bed_n or_o too_o frequent_a venery_n and_o for_o a_o correction_n of_o this_o distemper_n all_o these_o procurer_n and_o aggravator_n be_v spare_o to_o be_v use_v and_o some_o of_o they_o to_o be_v avoid_v and_o forbear_v but_o if_o this_o intemperate_a heat_n depend_v upon_o any_o other_o disease_n seat_v there_o disturb_v the_o office_n of_o the_o kidney_n and_o raise_v a_o preternatural_a heat_n then_o remedy_n must_v be_v apply_v to_o that_o as_o the_o nature_n thereof_o do_v require_v which_o be_v remove_v this_o heat_n will_v allay_v and_o cease_v imbecility_n and_o weakness_n do_v sometime_o affect_v the_o reins_o and_o a_o decay_n in_o the_o performance_n of_o their_o office_n may_v be_v perceive_v and_o if_o this_o be_v not_o the_o consequent_a of_o some_o manifest_a disease_n debilitate_v and_o render_v they_o incapable_a than_o you_o must_v know_v that_o there_o be_v a_o natural_a robor_fw-la and_o fortitude_n implant_v in_o every_o part_n by_o nature_n whereby_o they_o execute_v their_o function_n with_o integrity_n and_o constancy_n there_o be_v also_o a_o inequal_a distribution_n of_o this_o vigour_n and_o strength_n that_o some_o part_n natural_o be_v strong_a and_o durable_a in_o their_o station_n other_o be_v not_o so_o firm_o radicate_v in_o their_o principle_n but_o by_o time_n spontaneous_o fall_v off_o from_o their_o duty_n and_o decay_n much_o soon_o than_o other_o part_n of_o the_o body_n hence_o it_o be_v that_o some_o though_o regular_o live_v complain_v of_o this_o part_n other_o of_o that_o there_o be_v also_o occasion_n accident_n and_o different_a manner_n of_o live_v which_o we_o call_v diaetetic_a custom_n which_o as_o they_o be_v various_a do_v various_o injure_v and_o decay_v this_o or_o that_o part_n of_o the_o body_n and_o cause_v it_o to_o decline_v soon_o than_o the_o rest_n imbecility_n therefore_o of_o the_o reins_o come_v under_o some_o of_o these_o notion_n and_o have_v its_o original_n from_o thence_o which_o when_o such_o a_o case_n present_a examination_n be_v to_o be_v make_v to_o which_o of_o these_o the_o case_n belong_v and_o be_v to_o be_v ascribe_v now_o that_o which_o i_o call_v imbecility_n or_o a_o decay_a state_n be_v when_o the_o reins_o do_v not_o make_v a_o due_a secretion_n or_o separation_n of_o the_o serum_n from_o the_o blood_n and_o give_v it_o the_o urinary_a transmutation_n so_o that_o from_o hence_o the_o urine_n be_v but_o little_a and_o that_o not_o well_o digest_v the_o injurious_a consequent_n whereof_o be_v many_o for_o the_o blood_n remain_v too_o much_o dilute_v and_o overcharge_v with_o the_o serum_n or_o watery_a part_n which_o be_v distribute_v throughout_o the_o body_n and_o fall_v upon_o this_o or_o that_o part_n cause_v many_o hydropic_a disease_n and_o some_o of_o they_o mortal_a as_o example_n hereof_o may_v be_v give_v the_o next_o considerable_a be_v consumptive_a waste_n diminution_n or_o lessen_v of_o the_o kidney_n not_o by_o ulceration_n but_o exsiccation_n proceed_v from_o a_o hot_a and_o dry_a distemper_n of_o the_o kidney_n arrive_v to_o a_o colliquate_a hectic_a or_o tabes_fw-la which_o by_o time_n beget_v a_o consumption_n of_o the_o whole_a body_n procure_v sometime_o from_o a_o fallacious_a temperament_n there_o be_v feel_v a_o heaviness_n and_o weakness_n about_o the_o loin_n and_o the_o kidney_n do_v not_o perform_v their_o office_n aright_o inflammation_n sometime_o possess_v the_o reins_o cause_v by_o pain_n of_o the_o stone_n gravel_n or_o otherwise_o by_o obstruction_n sometime_o by_o a_o blow_n or_o fall_v also_o by_o a_o influx_n of_o blood_n or_o any_o foul_a corrupt_a matter_n transmute_v thither_o and_o lodge_v there_o obstruct_v the_o passage_n and_o cause_v a_o suppression_n
ignoble_a part_n or_o to_o such_o place_n where_o mean_n can_v better_o be_v use_v and_o more_o apt_a for_o recession_n or_o egression_n of_o the_o continent_n material_a cause_n but_o if_o the_o tumour_n apostemate_n the_o danger_n be_v great_a or_o less_o according_a to_o the_o nature_n and_o condition_n of_o the_o member_n or_o part_n if_o it_o indurate_v the_o danger_n be_v delay_v but_o if_o it_o corrupt_v the_o part_n the_o danger_n be_v great_a and_o more_o speedy_a in_o execution_n apostem_fw-la be_v that_o degree_n or_o state_n of_o a_o tumour_n when_o it_o be_v maturate_v or_o ripe_a which_o be_v call_v suppuration_n the_o material_a or_o humoral_a cause_n be_v then_o convert_v into_o a_o pus_fw-la or_o purulent_a matter_n and_o while_o this_o be_v in_o fieri_fw-la do_v all_o symptom_n be_v aggravate_v pain_n heat_n pulsation_n tension_n be_v great_a but_o be_v perfect_v they_o all_o decrease_v again_o and_o the_o patient_n find_v ease_n but_o not_o out_o of_o danger_n in_o these_o internal_a apostem_n for_o if_o it_o be_v so_o seat_v where_o there_o be_v no_o convenient_a vent_n or_o emunctory_a to_o discharge_v it_o the_o case_n be_v desperate_a as_o the_o humoral_a matter_n that_o form_v the_o tumour_n be_v more_o benign_a and_o good_a as_o pure_a blood_n so_o the_o convert_v pus_fw-la or_o purulent_a matter_n from_o thence_o do_v common_o answer_v it_o in_o goodness_n for_o of_o good_a blood_n and_o in_o sound_a body_n the_o maturation_n be_v more_o kind_o the_o pus_fw-la white_a mild_a and_o not_o endanger_v to_o corrupt_v the_o part_n but_o in_o foul_a deprave_a body_n and_o malignant_a disease_n apostemate_v matter_n be_v more_o putrid_a stink_a and_o venenous_a and_o do_v threaten_v a_o gangrene_n or_o mortification_n of_o the_o part_n and_o therefore_o such_o internal_a collection_n of_o matter_n in_o pestilential_a and_o malignant_a fever_n venereal_a pox_n small_a pox_n and_o such_o like_a be_v common_o mortal_a scirrhous_n tumour_n be_v such_o as_o when_o the_o continent_n matter_n do_v not_o maturate_a and_o become_v soft_a fit_a to_o break_v and_o discharge_v but_o grow_v hard_a and_o fine_v in_o the_o part_n not_o apt_a to_o be_v discharge_v or_o remove_v by_o discussion_n or_o suppuration_n and_o this_o the_o word_n scirrhus_n import_v from_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d induro_fw-la tumour_n in_o some_o part_n of_o the_o body_n be_v apt_a to_o suppurate_n as_o in_o the_o carnous_a or_o fleshy_a in_o other_o part_n as_o the_o joint_n tendon_n and_o ligament_n more_o incline_v to_o indurate_a and_o become_v scirrhous_a and_o the_o reason_n may_v be_v this_o that_o those_o part_n which_o take_v their_o origine_fw-la from_o blood_n be_v more_o prompt_a and_o ready_a to_o suppurate_a as_o the_o flesh_n but_o those_o which_o take_v their_o rise_n from_o seminal_a matter_n as_o the_o tendon_n ligament_n nerve_n &c_n &c_n they_o be_v more_o inclinable_a to_o scirrhosity_n or_o hardness_n but_o beside_o this_o disposition_n of_o the_o part_n affect_v there_o be_v also_o and_o chief_o a_o propension_n in_o the_o congest_a or_o influx_v matter_n of_o these_o tumour_n for_o by_o the_o different_a nature_n of_o humoral_a matter_n some_o be_v more_o fluxible_a and_o thin_a participate_v much_o of_o serosity_n and_o apt_a to_o transpire_v or_o be_v discuss_v other_o more_o yield_v to_o a_o preternatural_a digestion_n and_o suppuration_n as_o the_o blood_n that_o be_v pure_a and_o good_a other_o incline_v to_o be_v viscous_a coagulate_v and_o consequent_o to_o indurate_a as_o a_o feculent_a grumou_n or_o gross_a blood_n deprive_v of_o its_o serosity_n and_o far_o beside_o the_o disposition_n of_o part_n and_o that_o of_o the_o material_a cause_n incline_v to_o this_o scirrhosity_n there_o may_v also_o come_v in_o and_o be_v join_v with_o these_o a_o three_o promoter_n which_o in_o some_o case_n may_v be_v the_o chief_a cause_n and_o that_o be_v a_o ill_a method_n and_o injurious_a medicine_n so_o endeavour_v to_o remove_v may_v thereby_o fix_v and_o fasten_v the_o matter_n for_o thus_o a_o tumour_n which_o may_v probable_o be_v disperse_v may_v be_v change_v from_o its_o own_o capacity_n and_o tendency_n and_o become_v scirrhous_a and_o indurate_a as_o when_o constant_a or_o great_a cooler_n be_v administer_v to_o abate_v the_o symptomatical_a or_o concomitant_a fever_n the_o matter_n of_o the_o tumour_n be_v thereby_o fix_v and_o impact_v which_o otherwise_o may_v have_v surrender_v unto_o proper_a and_o powerful_a medicine_n due_o use_v and_o e_fw-la contrà _fw-la by_o too_o great_a dryer_n and_o heater_n the_o thin_a part_n be_v evaporate_v and_o the_o grosser_n remains_o therefore_o medio_fw-la tutissimus_fw-la ibis_fw-la good_a resolutive_a transpire_a medicine_n take_v their_o turn_n with_o the_o use_n of_o proper_a cathartic_n be_v the_o safe_a and_o bed_n way_n these_o scirrhous_a tumour_n although_o they_o be_v not_o so_o dangerous_a for_o the_o present_a except_o they_o be_v very_o great_a or_o cancerous_a yet_o they_o be_v the_o foundation_n of_o some_o chronic_n or_o linger_a disease_n which_o prove_v very_o contumacious_a and_o sometime_o incurable_a especial_o if_o the_o tumour_n be_v latent_fw-la and_o conceal_v and_o hectic_a fever_n sometime_o take_v its_o rise_n from_o hence_o which_o if_o you_o think_v to_o cure_v by_o emulsion_n restaurative_n and_o cool_a drink_n you_o will_v be_v much_o mistake_v in_o your_o purpose_n and_o endeavour_n these_o scirrhous_a tumour_n some_o be_v with_o pain_n some_o without_o those_o that_o have_v pain_n be_v more_o hopeful_a except_o they_o be_v cancerous_a but_o those_o which_o be_v insensible_a upon_o pressure_n be_v more_o difficult_a or_o incurable_a now_o according_a to_o the_o nature_n and_o degree_n of_o depravedness_n in_o the_o continent_n matter_n and_o from_o the_o part_n affect_v so_o be_v these_o tumour_n better_a or_o worse_o to_o be_v deal_v with_o and_o because_o these_o tumour_n be_v internal_a and_o hide_v from_o the_o eye_n therefore_o judgement_n be_v to_o be_v give_v of_o they_o from_o their_o situation_n and_o from_o the_o constitution_n with_o other_o circumstance_n of_o the_o patient_n body_n but_o although_o these_o scirrhous_a tumour_n be_v thus_o difficult_a to_o be_v undertake_v and_o manage_v yet_o these_o be_v not_o the_o worst_a and_o they_o may_v arrive_v far_o and_o to_o a_o more_o dangerous_a state_n as_o when_o tumour_n in_o their_o variation_n and_o degeneration_n do_v turn_v cancerous_a and_o this_o be_v apt_a to_o be_v in_o such_o body_n as_o abound_v with_o a_o black_a feculent_a blood_n or_o a_o thick_a blood_n adust_a by_o intemperate_a heat_n and_o by_o how_o much_o the_o blood_n thus_o exceed_v in_o this_o preternatural_a condition_n by_o so_o much_o the_o cancer_n be_v complete_v confirm_v and_o the_o worse_o and_o this_o supervene_v a_o scirrhus_n common_o as_o be_v a_o apt_a previous_a disposition_n but_o may_v happen_v also_o without_o a_o scirrhus_n precede_v from_o other_o tumour_n degenerate_v into_o cancer_n and_o therefore_o in_o the_o cure_n of_o scirrhous_a tumour_n great_a circumspection_n and_o diligence_n be_v to_o be_v use_v lest_o by_o their_o delay_n add_v continuance_n or_o improper_a usage_n of_o medicine_n these_o tumour_n do_v not_o become_v cancerous_a and_o desperate_a as_o sometime_o it_o fall_v out_o so_o now_o a_o tumour_n be_v say_v to_o be_v cancerous_a when_o it_o turn_v into_o a_o dark_a radish_n or_o livid_n and_o blackish_a colour_n declare_v this_o transmutation_n and_o degenerate_a state_n the_o beginning_n of_o these_o cancer_n be_v very_o small_a in_o compass_n as_o those_o that_o present_a outward_n do_v manifest_v their_o gradual_a enlargement_n but_o by_o time_n they_o increase_v and_o grow_v big_a with_o tumified_a vein_n round_o about_o these_o cancerous_a tumour_n may_v happen_v to_o any_o part_n of_o the_o body_n but_o chief_o and_o moult_v frequent_o in_o the_o upper_a part_n about_o the_o face_n as_o nose_n lip_n etc._n etc._n or_o the_o dug_n and_o other_o glandulous_a part_n also_o the_o womb_n be_v thus_o affect_v sometime_o from_o tumour_n there_o breed_v venereal_a or_o other_o degenerate_v cancerous_a these_o tumour_n sometime_o be_v occasion_v from_o the_o menstrual_a suppression_n in_o woman_n and_o heamorrhoidal_a in_o man_n and_o when_o it_o happen_v so_o those_o cause_n be_v to_o be_v remove_v with_o speed_n great_a skill_n and_o circumspection_n be_v to_o be_v use_v in_o tumour_n of_o this_o nature_n lest_o provoke_v the_o continent_n matter_n it_o grow_v more_o fierce_a eat_v and_o ulcerate_v and_o from_o a_o cancerous_a tumour_n it_o become_v a_o cancerous_a preside_a ulcer_n which_o be_v worse_o now_o the_o sign_n of_o this_o tumour_n incline_v to_o break_v and_o ulcerate_v be_v great_a heat_n and_o pulsation_n in_o the_o part_n the_o difficulty_n or_o incurability_n of_o cancer_n lie_v here_o for_o that_o the_o cancerous_a matter_n will_v not_o yield_v to_o digestion_n or_o discussion_n and_o this_o because_o the_o