a_o treatise_n of_o the_o reason_n of_o muscular_a motion_n or_o the_o efficient_a cause_n of_o the_o contraction_n of_o a_o muscle_n wherein_o most_o of_o the_o phaenomena_n about_o muscular_a motion_n be_v explain_v by_o richard_n boulton_n of_o the_o city_n of_o chester_n medicine_n proficiens_fw-la 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d london_n print_v by_o a._n and_o j._n churchill_n at_o the_o black_a swan_n in_o pater-noster-row_n 1697._o tractatum_fw-la hunc_fw-la cui_fw-la titulus_fw-la a_o treatise_n of_o the_o reason_n of_o muscular_a motion_n etc._n etc._n dignum_fw-la censemus_fw-la quî_fw-la imprimatur_fw-la samuel_n collins_n praeses_fw-la thomas_n burwell_n sen._n richard_n torless_a william_n dawes_n thomas_n gill_n censor_n datum_n in_o comitiis_fw-la censoriis_fw-la ex_fw-la aedibus_fw-la collegii_fw-la nostri_fw-la sept._n 11._o 1696._o to_o the_o most_o learned_a and_o ever_o honour_a dr._n collins_n precedent_n dr._n thomas_n burwell_n dr._n richard_n torlesse_a dr._n william_n dawes_n dr._n thomas_n gill._n censor_n of_o the_o college_n of_o physician_n this_o treatise_n be_v humble_o dedicate_v by_o your_o most_o faithful_a and_o obedient_a servant_n r._n boulton_n to_o the_o reader_n i_o have_v examine_v this_o treatise_n with_o the_o strict_a reason_n that_o i_o be_o master_n of_o and_o it_o appear_v to_o i_o reasonable_a in_o every_o particular_a but_o i_o be_o altogether_o desirous_a of_o truth_n and_o will_v not_o out_o of_o any_o fond_a opinion_n of_o my_o own_o hypothesis_n receive_v it_o soon_o than_o another_o man_n i_o be_o most_o incline_v to_o suspect_v whatever_o be_v a_o faetus_fw-la of_o my_o own_o brain_n if_o it_o may_v be_v any_o way_n serviceable_a to_o other_o i_o have_v my_o desire_n the_o content_n the_o usefulness_n of_o muscular_a motion_n as_o it_o tend_v to_o the_o maintenance_n of_o life_n page_z 1_o with_o respect_n to_o the_o soul_n and_o the_o animal_n function_n p._n 3_o dr._n willis_n opinion_n examine_v p._n 7_o mr._n cowper_n opinion_n examine_v p._n 20_o dr._n ridley_n opinion_n examine_v p._n 30_o the_o structure_n of_o a_o muscle_n p._n 40_o the_o formal_a cause_n of_o the_o contraction_n of_o a_o muscle_n p._n 41_o vessel_n implant_v into_o a_o muscle_n p._n 42_o their_o distribution_n p._n 43_o and_o termination_n in_o small_a glandule_n p._n 45_o what_o a_o gland_n be_v p._n 47_o the_o use_n of_o the_o nerve_n p._n 52_o and_o artery_n insert_v in_o the_o gland_n p._n 53_o to_o prepare_v a_o subtle_a liquor_n ibid._n the_o use_n of_o it_o p._n 54_o the_o reason_n of_o tonick_n motion_n p._n 59_o of_o local_a motion_n p._n 60_o the_o use_n of_o the_o lymphduct_n p._n 68_o the_o nature_n of_o the_o liquor_n and_o the_o manner_n of_o its_o preparation_n p._n 69_o by_o fermentation_n p._n 70_o prove_v p._n 72_o the_o reason_n of_o involuntary_a motion_n p._n 82_o why_o the_o systole_n of_o the_o heart_n be_v interrupt_v with_o frequent_a diastole_n p._n 86_o why_o the_o muscle_n serve_v to_o respiration_n be_v in_o some_o measure_n subject_a to_o our_o appetite_n p._n 90_o some_o phaenomena_n about_o muscular_a motion_n explain_v p._n 93_o the_o reason_n of_o convulsion_n p._n 103_o of_o the_o palpitation_n of_o the_o heart_n p._n 109_o of_o the_o cramp_n p._n 111_o of_o the_o subsultus_fw-la tendinum_fw-la in_o fever_n p._n 113_o of_o spasmus_fw-la lynicus_n p._n 114_o of_o the_o reason_n of_o muscular_a motion_n or_o the_o efficient_a cause_n of_o the_o contraction_n of_o a_o muscle_n etc._n etc._n if_o we_o consider_v the_o usefulness_n of_o muscular_a motion_n life_n with_o respect_n to_o a_o individual_a and_o that_o either_o as_o it_o tend_v to_o the_o maintenance_n of_o life_n or_o the_o perfection_n of_o man_n that_o be_v with_o respect_n to_o the_o soul_n and_o the_o animal_n function_n it_o be_v the_o very_a spring_n upon_o which_o all_o our_o action_n both_o natural_a vital_a and_o animal_n whole_o depend_v by_o the_o assistance_n of_o muscular_a motion_n all_o the_o part_n of_o our_o body_n perform_v their_o particular_a office_n our_o food_n be_v prepare_v by_o mastication_n and_o convey_v to_o the_o stomach_n the_o concoct_v chymus_fw-la be_v thence_o expel_v into_o the_o intestine_n where_o the_o pure_a chyle_n be_v separate_v from_o the_o impure_a faeces_fw-la every_o peculiar_a liquor_n circulate_v through_o its_o distinct_a and_o proper_a vessel_n the_o chyle_n through_o its_o lacteal_v and_o the_o lympha_fw-la through_o its_o duct_n and_o the_o mass_n of_o blood_n be_v disribute_v through_o the_o artery_n that_o all_o the_o part_n of_o the_o body_n both_o principal_a and_o subsubservient_fw-fr noble_a and_o ignoble_a may_v receive_v their_o proper_a liquor_n in_o a_o word_n it_o be_v by_o this_o very_a action_n of_o muscular_a motion_n that_o 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d if_o we_o respect_v the_o animal_n function_n function_n they_o so_o much_o depend_v upon_o muscular_a motion_n that_o when_o the_o heart_n cease_v to_o move_v all_o the_o faculty_n of_o the_o soul_n be_v present_o extinguish_v the_o faculty_n of_o the_o soul_n be_v not_o only_o dependent_a on_o involuntary_a but_o also_o voluntary_a motion_n without_o which_o both_o our_o eye_n and_o ear_n will_v be_v unfit_a to_o receive_v external_a object_n and_o man_n will_v be_v endow_v with_o a_o sensitive_a and_o rational_a soul_n to_o no_o purpose_n our_o outward_a sense_n will_v in_o vain_a receive_v external_a object_n unless_o we_o have_v a_o intelligent_a faculty_n in_o vain_a shall_v we_o understand_v unless_o we_o have_v reason_n to_o distinguish_v good_a from_o evil_n that_o we_o may_v desire_v the_o one_o and_o contemn_v the_o other_o in_o vain_a also_o will_v be_v the_o dictate_v of_o our_o reason_n if_o we_o have_v not_o a_o loco-motive_n faculty_n to_o pursue_v those_o thing_n we_o desire_v and_o to_o flee_v from_o those_o thing_n which_o we_o be_v willing_a to_o avoid_v but_o by_o muscular_a motion_n the_o dictate_v of_o our_o reason_n according_o as_o they_o be_v bias_v by_o our_o appetite_n be_v put_v into_o action_n and_o the_o intimate_a result_v of_o all_o our_o faculty_n be_v bring_v to_o light_n muscular_a motion_n be_v the_o very_a index_n animi_fw-la by_o which_o the_o temper_n and_o disposition_n of_o the_o animal_n faculty_n be_v make_v evident_a it_o be_v the_o ultimate_a result_n of_o our_o most_o secret_a thought_n and_o of_o our_o will_n so_o that_o if_o we_o weigh_v but_o the_o mutual_a dependence_n of_o all_o the_o part_n of_o a_o man_n body_n part_n there_o be_v no_o reason_n that_o a_o muscle_n shall_v be_v term_v a_o ignoble_a part_n since_o by_o the_o loss_n of_o a_o single_a one_o either_o the_o natural_a vital_a or_o animal_n faculty_n be_v in_o some_o measure_n vitiate_v the_o stomach_n the_o liver_n the_o spleen_n the_o lung_n etc._n etc._n be_v all_o subordinate_a and_o subservient_fw-fr to_o the_o principle_n faculty_n of_o the_o soul_n in_o as_o much_o as_o they_o by_o their_o mutual_a symbolum_n prepare_v the_o pabulum_fw-la of_o the_o animal_n spirit_n but_o the_o muscle_n design_v for_o motion_n especial_o voluntary_a in_o as_o much_o as_o the_o most_o perfect_a and_o refine_a action_n of_o the_o soul_n be_v perform_v and_o express_v by_o muscular_a motion_n be_v of_o a_o more_o noble_a use_n the_o perfection_n of_o man_n consist_v more_o immediate_o on_o the_o energy_n and_o execution_n of_o the_o principal_a faculty_n of_o the_o soul_n than_o in_o the_o subordinate_a and_o subservient_fw-fr faculty_n both_o natural_a and_o vital_a for_o as_o much_o as_o the_o life_n and_o perfection_n of_o man_n so_o much_o depend_v on_o muscular_a motion_n i_o shall_v inquire_v into_o the_o efficient_a cause_n of_o it_o but_o before_o i_o propose_v my_o own_o hypothesis_n it_o be_v necessary_a that_o i_o first_o confute_v what_o have_v hitherto_o be_v say_v on_o this_o subject_n nevertheless_o because_o it_o will_v be_v too_o tedious_a to_o examine_v the_o opinion_n of_o so_o many_o author_n i_o will_v only_o show_v the_o error_n of_o two_o or_o three_o of_o the_o late_a and_o most_o considerable_a the_o most_o learned_a and_o famous_a dr._n willis_n conjecture_n examine_v that_o the_o spirit_n be_v convey_v to_o the_o tendon_n of_o a_o muscle_n and_o be_v there_o plentiful_o lay_v up_o as_o in_o a_o convenient_a storehouse_n which_o spirit_n be_v of_o a_o agile_a and_o elastic_a nature_n as_o far_o as_o they_o be_v able_a and_o be_v permit_v always_o endeavour_v to_o expand_v themselves_o and_o that_o when_o a_o instinct_n to_o perform_v muscular_a motion_n be_v carry_v from_o the_o brain_n or_o cerebell_n to_o this_o common_a storehouse_n they_o present_o leap_v out_o of_o the_o tendinous_a into_o the_o fleshy_a fiber_n where_o they_o meet_v with_o active_a principle_n of_o another_o nature_n supply_v by_o the_o mass_n of_o blood_n which_o two_o strong_o &_o mutual_o ferment_v stuff_v up_o and_o tumifie_v the_o fleshy_a fiber_n whence_o proceed_v the_o
the_o blood_n be_v a_o pondus_fw-la by_o which_o the_o action_n of_o a_o muscle_n be_v perform_v the_o ground_n of_o this_o suspicion_n be_v chief_o take_v from_o two_o experiment_n the_o first_o be_v a_o ligature_n on_o the_o descend_v ttunk_v of_o the_o aorta_fw-mi whereby_o all_o the_o inferior_a part_n become_v destitute_a of_o motion_n which_o they_o recover_v again_o when_o that_o ligature_n be_v loose_v the_o second_o be_v to_o be_v take_v for_o a_o more_o surprise_v argument_n because_o after_o a_o cessation_n of_o motion_n the_o muscle_n of_o the_o leg_n renew_v their_o contraction_n by_o a_o injection_n of_o water_n into_o the_o crural_a artery_n but_o that_o there_o be_v no_o reason_n to_o assert_v that_o the_o blood_n act_v as_o a_o pondus_fw-la from_o these_o experiment_n will_v hereafter_o sufficient_o appear_v by_o give_v other_o reason_n for_o these_o phenomena_n in_o the_o mean_a time_n to_o evince_v pondus_fw-la that_o the_o blood_n as_o a_o pondus_fw-la do_v in_o no_o wise_a help_n the_o contraction_n of_o a_o muscle_n but_o do_v on_o the_o contrary_a much_o interrupt_v and_o resist_v the_o intumescence_n of_o the_o musculous_a fiber_n argument_n by_o which_o the_o contraction_n of_o a_o muscle_n be_v perform_v let_v any_o one_o hold_v his_o hand_n before_o a_o fire_n with_o his_o arm_n perpendicular_a continue_v they_o in_o that_o posture_n till_o he_o feel_v the_o musculous_a part_n well_o fill_v with_o blood_n then_o lift_v up_o both_o his_o hand_n let_v he_o hold_v they_o up_o as_o high_a as_o he_o can_v till_o the_o pondus_fw-la of_o the_o blood_n be_v drain_v and_o the_o vein_n which_o before_o be_v full_a and_o tumid_a become_v flaccid_n and_o empty_a and_o he_o will_v move_v his_o finger_n much_o more_o easy_o and_o swift_a when_o the_o muscle_n be_v ease_v of_o the_o pondus_fw-la of_o blood_n than_o he_o do_v whilst_o his_o hand_n be_v dependent_a yet_o certain_o there_o be_v a_o great_a pondus_fw-la of_o blood_n upon_o the_o muscle_n in_o the_o former_a posture_n whilst_o they_o be_v tumid_a than_o in_o the_o latter_a when_o empty_v of_o superfluous_a blood_n another_o argument_n to_o prove_v second_o that_o the_o pondus_fw-la of_o the_o blood_n do_v not_o at_o all_o promote_v the_o contraction_n of_o a_o muscle_n may_v be_v take_v from_o the_o observation_n of_o cacochymick_a body_n who_o be_v far_o more_o dull_a and_o unapt_a for_o motion_n than_o healthful_a people_n who_o vein_n and_o artery_n be_v moderate_o fill_v with_o blood_n which_o be_v not_o so_o thick_a and_o heavy_a for_o in_o cacochymick_a body_n there_o be_v a_o great_a pondus_fw-la of_o blood_n but_o because_o it_o do_v not_o yield_v matter_n for_o to_o swell_v the_o carnous_a fiber_n as_o plentiful_o as_o blood_n of_o a_o more_o healthful_a constitution_n motion_n be_v not_o so_o brisk_a and_o strong_a whereas_o if_o the_o pondus_fw-la of_o the_o blood_n do_v any_o way_n contribute_v to_o the_o performance_n of_o muscular_a motion_n they_o will_v be_v far_o more_o strong_a for_o the_o thick_a the_o blood_n be_v the_o great_a be_v the_o pondus_fw-la in_o the_o muscle_n of_o the_o leg_n and_o thigh_n there_o be_v always_o three_o when_o the_o body_n be_v erect_v a_o great_a weight_n of_o blood_n than_o on_o the_o muscle_n belong_v to_o the_o hand_n and_o arm_n and_o yet_o the_o latter_a be_v far_o more_o agile_a and_o nimble_a in_o motion_n again_o if_o we_o but_o make_v a_o ligature_n two_o or_o three_o finger_n breadth_n above_o the_o cubit_n so_o as_o to_o hinder_v the_o reflux_n but_o not_o the_o influx_n of_o the_o blood_n when_o the_o sanguiferous_a vessel_n be_v swell_v and_o the_o muscle_n well_o fill_v they_o be_v render_v much_o more_o unapt_a for_o motion_n which_o evident_o show_v that_o the_o more_o the_o sanguiferous_a vessel_n be_v distend_v the_o more_o the_o motion_n of_o a_o muscle_n be_v hinder_v because_o when_o the_o vessel_n be_v dilate_v they_o resist_v the_o intumescence_n of_o the_o carnous_a fiber_n and_o consequent_o the_o contraction_n of_o a_o muscle_n furthermore_o that_o the_o contraction_n of_o a_o muscle_n be_v not_o perform_v by_o the_o pondus_fw-la of_o the_o blood_n be_v apparent_o evident_a in_o the_o follow_a experiment_n five_o viz._n make_v a_o ligature_n two_o or_o three_o finger_n breadth_n above_o the_o cubit_n so_o strong_a as_o to_o stop_v the_o circulation_n of_o the_o blood_n then_o open_a the_o large_a vein_n with_o the_o common_a instrument_n and_o the_o blood_n which_o more_o than_o usual_o swell_v up_o the_o sanguiferous_a vessel_n will_v leap_v forth_o but_o present_o for_o want_v of_o subsequent_a matter_n and_o due_a circulation_n the_o vein_n fall_v and_o the_o blood_n cease_v to_o run_v yet_o by_o a_o contraction_n of_o the_o muscle_n to_o which_o that_o vein_n lead_v forthwith_o part_n of_o the_o blood_n which_o lie_v in_o the_o muscle_n be_v force_v out_o which_o plain_o show_v there_o be_v less_o blood_n in_o a_o contract_a muscle_n than_o before_o contraction_n the_o same_o appear_v also_o in_o run_v six_o or_o any_o other_o violent_a exercise_n in_o which_o most_o of_o the_o muscle_n be_v contract_v for_o present_o the_o blood_n flow_v more_o than_o usual_o upon_o the_o tender_a lung_n and_o cause_v a_o intolerable_a shortness_n of_o breath_n because_o by_o a_o intumescence_n of_o the_o fleshy_a fiber_n the_o muscle_n be_v not_o only_o make_v incapable_a of_o receive_v so_o much_o arterial_a blood_n as_o before_o contraction_n but_o also_o because_o the_o blood_n which_o lie_v in_o the_o veinous_a duct_n be_v drive_v out_o more_o forcible_o upon_o the_o heart_n and_o the_o heart_n be_v overwhelm_v drive_v it_o out_o upon_o the_o lung_n whence_o proceed_v that_o palpiration_n of_o the_o heart_n upon_o violent_a motion_n not_o direct_o as_o dr._n croone_a suppose_v because_o a_o instinct_n be_v send_v from_o the_o brain_n to_o raise_v strong_a pulsation_n that_o the_o blood_n may_v forcible_o be_v drive_v into_o the_o muscle_n and_o thereby_o cause_v contraction_n for_o then_o why_o do_v it_o not_o at_o the_o first_o instinct_n thus_o oppress_v the_o lung_n with_o its_o quantaty_n but_o this_o strong_a palpitation_n be_v accidental_a for_o when_o the_o blood_n be_v more_o than_o usual_o drive_v upon_o the_o heart_n and_o not_o so_o plentiful_o receive_v by_o the_o muscle_n by_o degree_n it_o oppress_v the_o heart_n with_o its_o quantity_n and_o the_o animal_n power_n be_v sensible_a of_o the_o oppression_n raise_v strong_a systole_n to_o drive_v it_o out_o which_o present_o be_v receive_v and_o heap_v up_o in_o the_o lung_n as_o a_o part_n less_o able_a to_o resist_v its_o violent_a incursion_n nay_o many_o time_n when_o the_o vessel_n be_v well_o fill_v with_o blood_n by_o violent_a and_o frequent_a exagitation_n betwixt_o the_o contraction_n of_o the_o heart_n and_o of_o the_o muscle_n its_o texture_n be_v so_o loosen_a that_o it_o ferment_n and_o boil_v up_o so_o that_o the_o lung_n be_v not_o only_o swell_v up_o and_o almost_o stifle_v be_v render_v uncapable_a of_o receive_v air_n but_o it_o be_v also_o more_o strong_o &_o forcible_o drive_v into_o the_o muscle_n themselves_o and_o there_o distend_v the_o sanguiferous_a vessel_n hinder_v the_o intumescence_n of_o the_o fiber_n and_o thereby_o the_o contraction_n of_o the_o muscle_n so_o that_o i_o have_v not_o once_o try_v this_o experiment_n find_v such_o a_o oppression_n on_o my_o whole_a thorax_n and_o such_o contrary_a and_o in_o some_o measure_n painful_a endeavour_n betwixt_o the_o sanguiferous_a vessel_n tumify_v and_o the_o carnous_a fiber_n strive_v to_o swell_v that_o i_o be_v force_v to_o lay_v i_o down_o to_o the_o end_n that_o the_o carnous_a fiber_n be_v flaccid_n may_v give_v way_n to_o the_o incourse_n of_o the_o blood_n and_o by_o receive_v it_o more_o plentiful_o may_v case_v both_o my_o thorax_n of_o its_o oppression_n and_o that_o the_o carnous_a fiber_n yield_v to_o the_o sanguiferous_a vessel_n may_v put_v a_o end_n to_o that_o uneasy_a contention_n thus_o much_o i_o think_v be_v sufficient_a to_o prove_v that_o the_o blood_n as_o a_o pondus_fw-la hinder_v the_o contraction_n of_o a_o muscle_n dr._n ridley_n suppose_v examine_v that_o the_o nervous_a and_o carnous_a fiber_n be_v only_o a_o congery_n of_o fluids_n contain_v in_o certain_a vessel_n and_o that_o by_o reason_n of_o a_o plenitude_n in_o the_o aforesaid_a vessel_n the_o whole_a machine_n be_v in_o a_o constant_a aequilibrium_fw-la so_o that_o it_o will_v follow_v upon_o the_o common_a postulatum_fw-la viz._n that_o the_o sensitive_a or_o rational_a soul_n can_v command_v the_o animal_n spirit_n into_o a_o primus_fw-la impetus_fw-la and_o that_o part_n of_o that_o liquor_n whenever_o a_o muscle_n be_v contract_v be_v transmit_v through_o the_o vessel_n from_o the_o brain_n to_o its_o carnous_a fiber_n and_o cause_v the_o intumescence_n of_o a_o muscle_n the_o same_o liquor_n at_o
to_o get_v it_o forward_o mr._n cowper_n mention_n a_o experiment_n three_o how_o by_o a_o injection_n of_o water_n into_o the_o crural_a artery_n the_o muscle_n of_o the_o leg_n renew_v their_o contraction_n from_o this_o he_o will_v infer_v that_o muscular_a motion_n be_v perform_v by_o the_o blood_n as_o a_o pondus_fw-la but_o though_o his_o myotomia_n argue_v it_o come_v from_o a_o inquisitive_a author_n yet_o i_o rather_o an_o full_o persuade_v that_o the_o blood_n do_v not_o act_n as_o a_o pondus_fw-la because_o this_o experiment_n plead_v against_o it_o but_o to_o avoid_v a_o long_a dispute_n i_o shall_v only_o give_v the_o reason_n of_o the_o phaenomenon_n before_o the_o injection_n of_o this_o water_n the_o branch_n of_o the_o artery_n be_v full_a of_o blood_n and_o arterial_a juice_n and_o when_o by_o the_o mixture_n of_o the_o water_n with_o this_o juice_n it_o be_v attenuate_v and_o drive_v into_o the_o gland_n fast_a than_o it_o can_v be_v receive_v by_o the_o venous_a channel_n the_o most_o subtle_a part_n be_v by_o the_o force_n of_o injection_n strain_v into_o the_o fiber_n and_o distend_v they_o so_o as_o to_o contract_v the_o muscle_n perhaps_o here_o it_o will_v be_v object_v that_o if_o the_o water_n can_v thus_o pass_v through_o into_o the_o fiber_n what_o need_n be_v there_o that_o the_o nerve_n shall_v lay_v down_o their_o content_n in_o the_o glandule_n i_o answer_v that_o the_o water_n be_v thin_a and_o apt_a to_o pass_v through_o those_o duct_n than_o the_o arterial_a juice_n which_o be_v thick_a and_o viscid_a wherefore_o it_o be_v necessary_a that_o the_o nerve_n shall_v lay_v down_o their_o content_n there_o to_o attenuate_v and_o rarisie_n this_o thick_a juice_n i_o have_v see_v people_n incline_v to_o a_o dropsy_n four_o who_o blood_n and_o serum_n be_v much_o dilute_v can_v move_v much_o more_o nimble_o though_o more_o seeble_o than_o some_o of_o a_o healthful_a constitution_n who_o blood_n and_o this_o arterial_a juice_n be_v thick_a and_o not_o so_o much_o dilute_v which_o do_v plain_o show_v that_o the_o thin_a the_o blood_n be_v and_o the_o more_o dilute_v the_o nutritious_a juice_n the_o less_o quantity_n of_o spirit_n be_v require_v to_o subtilise_v it_o and_o make_v it_o capable_a of_o pass_v into_o the_o fiber_n it_o may_v easy_o be_v observe_v that_o those_o people_n who_o spirit_n be_v strong_a five_o and_o their_o arterial_a juice_n very_o thin_a be_v nimble_a but_o the_o contraction_n of_o their_o muscle_n be_v not_o so_o durable_a as_o of_o those_o who_o serum_n be_v of_o a_o thick_a consistence_n for_o though_o in_o the_o former_a more_o of_o the_o subtle_a liquor_n be_v prepare_v yet_o by_o reason_n of_o its_o tenuity_n it_o be_v soon_o receive_v and_o carry_v off_o by_o the_o lymphduct_n which_o make_v the_o contraction_n short_a those_o who_o blood_n abound_v with_o fix_a salt_n &_o phlegmatic_a humour_n six_o which_o too_o much_o dull_a and_o resist_v the_o activity_n of_o the_o animal_n spirit_n be_v always_o slow_a and_o unapt_a for_o motion_n whereas_o if_o the_o blood_n act_v as_o a_o pondus_fw-la they_o must_v be_v more_o nimble_a and_o strong_a because_o the_o thick_a the_o blood_n be_v the_o heavy_a will_v be_v the_o pondus_fw-la as_o muscular_a motion_n be_v many_o way_n vitiate_v by_o the_o fault_n of_o the_o arterial_a juice_n or_o of_o the_o spirit_n and_o consequent_o by_o the_o distemperature_n of_o this_o subtle_a liquor_n so_o it_o be_v very_o often_o deprave_v and_o according_o as_o the_o mass_n of_o blood_n degenerate_v from_o its_o genuine_a and_o proper_a nature_n be_v produce_v various_a disease_n or_o symptom_n of_o disease_n viz._n cramp_n convulsion_n palpitation_n of_o the_o heart_n leap_v of_o the_o tendon_n in_o fever_n etc._n etc._n for_o a_o far_a illustration_n of_o my_o hypothesis_n before_o i_o conclude_v i_o will_v give_v the_o reason_n of_o these_o phonomaena_n when_o by_o a_o abuse_n of_o non-naturals_a the_o ferment_n of_o the_o viscera_n be_v pervert_v convulsion_n and_o by_o the_o fault_n of_o the_o pancreatic_a juice_n and_o of_o the_o spleen_n a_o acid_n or_o austere_a salt_n be_v carry_v forth_o into_o a_o flux_n present_o the_o mass_n of_o blood_n be_v vitiate_a the_o animal_n spirit_n meet_v with_o this_o vicious_a salt_n and_o ferment_v in_o the_o gland_n do_v there_o cause_v irregular_a explosion_n of_o matter_n into_o the_o carnous_a fiber_n subtilise_v in_o that_o fermentation_n whence_o follow_v irregular_a contraction_n of_o the_o muscle_n why_o convulsive_a paroxysm_n come_v at_o uncertain_a time_n will_v easy_o appear_v if_o we_o do_v but_o consider_v the_o procatartick_a cause_n among_o which_o i_o shall_v only_o mention_v two_o viz._n the_o quantity_n of_o morbific_n matter_n irritate_v nature_n to_o a_o expulsion_n of_o it_o and_o sudden_a passion_n of_o the_o mind_n the_o quantity_n of_o morbific_n matter_n be_v far_o great_a in_o some_o body_n than_o in_o other_o before_o the_o spirit_n be_v able_a to_o recover_v themselves_o and_o to_o endeavour_v a_o expulsion_n of_o it_o in_o the_o former_a case_n convulsion_n be_v universal_a and_o seize_v the_o whole_a body_n in_o the_o latter_a particular_a the_o morbific_n matter_n be_v accidental_o drive_v more_o on_o one_o part_n than_o another_o again_o in_o some_o body_n it_o be_v soon_o heap_v up_o be_v generate_v in_o great_a quantity_n the_o matter_n heap_v up_o at_o the_o first_o be_v very_o crude_a and_o thick_a and_o although_o it_o be_v cast_v forth_o into_o and_o circulate_v through_o the_o musculous_a part_n and_o continual_o ferment_n with_o the_o spirit_n in_o the_o glandule_n yet_o because_o it_o be_v not_o sufficient_o attenuate_v to_o be_v drive_v forth_o into_o the_o fleshy_a fiber_n till_o by_o frequent_a circulation_n and_o fermentation_n it_o be_v exalt_v from_o its_o state_n of_o sixedness_n to_o a_o more_o volatile_a no_o convulsion_n succeed_v moreover_o as_o long_o as_o it_o continue_v in_o its_o state_n of_o crudity_n the_o animal_n spirit_n be_v much_o dull_v and_o their_o activity_n quash_v by_o mix_v with_o it_o but_o it_o be_v at_o the_o length_n subtilise_v and_o rarify_v by_o frequent_a circulation_n the_o animal_n spirit_n recover_v they_o self_n and_o violent_o ferment_v with_o it_o in_o the_o gland_n carry_v this_o vicious_a juice_n explosive_o into_o the_o fiber_n the_o reason_n why_o this_o motion_n be_v involuntary_a be_v be_v cause_n it_o be_v not_o produce_v by_o a_o great_a quantity_n of_o spirit_n flow_v from_o the_o brain_n according_o as_o the_o pore_n be_v dilate_v by_o our_o appetite_n but_o by_o a_o mixture_n of_o morbific_a and_o fermentitious_a particle_n which_o cause_n preternatural_a fermentation_n &_o expulsion_n of_o matter_n attenuate_v thereby_o convulsive_a sit_v be_v sometime_o bring_v on_o before_o the_o morbific_a matter_n gradual_o arrive_v at_o this_o state_n of_o tenuity_n when_o upon_o sudden_a passion_n of_o the_o mind_n the_o animal_n faculty_n quit_v their_o station_n and_o be_v overpower_a by_o external_a object_n can_v no_o long_o moderate_v the_o emanation_n of_o the_o animal_n spirit_n the_o formal_a cause_n of_o the_o irregular_a emanation_n of_o the_o spirit_n in_o these_o convulsion_n be_v this_o the_o pore_n of_o the_o brain_n be_v shut_v up_o to_o keep_v out_o external_a object_n heap_v up_o the_o spirit_n till_o by_o reason_n of_o their_o quantity_n the_o pore_n can_v no_o long_o retain_v they_o and_o then_o the_o spirit_n rush_v out_o quà _fw-la datur_fw-la portà _fw-la in_o a_o great_a quantity_n and_o violent_o set_v upon_o the_o crude_a juice_n which_o they_o meet_v with_o in_o the_o glandule_n strong_o ferment_n attenuate_v and_o carry_v it_o forth_o into_o the_o fiber_n of_o the_o muscle_n wherein_o the_o spirit_n be_v thus_o accidental_o lay_v down_o the_o brain_n be_v thus_o empty_v the_o pore_n be_v shut_v up_o again_o till_o the_o quantity_n of_o spirit_n make_v way_n again_o and_o so_o successive_o follow_v convulsive_a motion_n in_o this_o or_o that_o part_n wherever_o the_o spirit_n set_v upon_o the_o crude_a morbific_n matter_n the_o 〈◊〉_d of_o the_o heart_n as_o the_o 〈◊〉_d ed_z dr._n 〈◊〉_d have_v note_v 〈◊〉_d proceed_v 〈◊〉_d convulsive_a motion_n the_o reason_n why_o the_o morbific_a matter_n only_o show_v itself_o in_o this_o part_n and_o at_o the_o same_o time_n in_o no_o other_o part_n of_o the_o body_n in_o this_o the_o mass_n of_o blood_n 〈◊〉_d nate_v with_o a_o morbific_a 〈◊〉_d and_o whatever_o be_v the_o nature_n of_o it_o since_o it_o be_v 〈◊〉_d 〈◊〉_d the_o whole_a body_n 〈◊〉_d 〈◊〉_d rational_o expect_v universal_a convulsion_n as_o well_o as_o 〈◊〉_d but_o this_o morbific_a matter_n be_v as_o yet_o crude_a and_o not_o of_o a_o sufficient_a quantity_n 〈◊〉_d 〈◊〉_d nature_n in_o all_o the_o part_n of_o the_o body_n these_o effect_n be_v only_o produce_v in_o this_o part_n where_o a_o large_a quantity_n of_o spirit_n be_v
each_o muscle_n which_o according_a to_o anatomist_n be_v four_o nerve_n artery_n vein_n and_o lymphduct_n muscle_n the_o nerve_n and_o artery_n furnish_v the_o muscle_n with_o spirit_n and_o blood_n the_o vein_n and_o lymphduct_n carry_v back_o the_o superfluity_n of_o blood_n and_o lympha_fw-la the_o branch_n of_o all_o these_o vessel_n be_v minutely_o distribute_v through_o the_o whole_a muscle_n distribution_n and_o by_o a_o intermixture_n and_o texture_n of_o the_o most_o minute_n and_o subtle_a branch_n of_o the_o same_o be_v form_v that_o substance_n which_o fill_v up_o the_o interstice_n of_o the_o fiber_n and_o which_o denominate_v the_o whole_a belly_n of_o a_o muscle_n fleshy_a the_o colour_n of_o these_o vessel_n as_o of_o all_o other_o be_v without_o doubt_n white_a but_o by_o the_o content_n of_o the_o sanguiferous_a vessel_n the_o whole_a belly_n of_o a_o muscle_n be_v colour_v red._n the_o termination_n of_o these_o vessel_n be_v so_o minute_n and_o small_a so_o brittle_a and_o subject_a to_o be_v break_v that_o it_o be_v as_o difficult_a to_o trace_v and_o find_v their_o termination_n and_o insertion_n as_o to_o divide_v a_o hair_n into_o a_o hundred_o part_n and_o though_o many_o thing_n be_v make_v visible_a by_o the_o help_n of_o microscope_n which_o be_v otherwise_o too_o subtle_a to_o be_v discern_v and_o discover_v by_o the_o naked_a eye_n yet_o i_o be_o not_o without_o reason_n persuade_v that_o the_o termination_n of_o these_o vessel_n can_v be_v perceive_v by_o the_o help_n of_o a_o microscope_n some_o indeed_o whatever_o they_o think_v be_v probable_a lest_o it_o shall_v not_o be_v credit_v present_o strenuous_o affirm_v they_o see_v it_o with_o their_o microscope_n and_o so_o easy_o impose_v on_o those_o that_o less_o inquire_v after_o truth_n themselves_o but_o take_v it_o on_o trust_n from_o other_o and_o perhaps_o prevent_v those_o not_o so_o exquisite_o skilled_a in_o microscope_n from_o make_v any_o further_a search_n after_o truth_n i_o shall_v not_o here_o say_v that_o what_o i_o propose_v concern_v the_o termination_n of_o these_o vessel_n be_v see_v with_o any_o microscope_n but_o shall_v declare_v my_o opinion_n in_o this_o matter_n too_o subtle_a for_o any_o microscope_n but_o reason_n it_o be_v impossible_a for_o any_o one_o to_o understand_v the_o true_a reason_n of_o muscular_a motion_n gland_n unless_o first_o acquaint_v with_o the_o distribution_n of_o these_o vessel_n and_o their_o content_n first_o i_o conceive_v that_o as_o the_o nerve_n artery_n and_o vein_n be_v all_o distribute_v through_o a_o muscle_n so_o it_o be_v but_o reasonable_a to_o conclude_v that_o their_o minute_n and_o subtle_a twig_n be_v all_o before_o they_o terminate_v interweave_v and_o mix_v with_o one_o another_o and_o if_o so_o it_o will_v not_o be_v absurd_a to_o imagine_v that_o they_o all_o end_n as_o it_o be_v in_o small_a and_o diminutive_a gland_n and_o if_o the_o end_n of_o the_o vessel_n be_v so_o small_a that_o their_o termination_n can_v be_v perceive_v by_o a_o microscope_n these_o glandule_n compose_v of_o the_o invisible_a end_n of_o the_o aforesaid_a vessel_n must_v needs_o be_v very_o small_a and_o fine_a and_o consequent_o may_v not_o be_v perceive_v by_o the_o help_n of_o extraordinary_a microscope_n from_o these_o glandule_n thus_o form_v be_v derive_v short_a duct_n or_o passage_n for_o the_o conveyance_n of_o a_o subtle_a liquor_n out_o of_o the_o aforesaid_a glandule_n into_o the_o cavity_n of_o the_o carnous_a fiber_n this_o passage_n very_o likely_a may_v be_v compose_v of_o the_o external_a arterial_a coat_n into_o the_o cavity_n of_o the_o carnous_a fiber_n beside_o these_o duct_n the_o twig_n of_o the_o lymphduct_n be_v also_o insert_v to_o carry_v back_o a_o superfluous_a lympha_fw-la if_o any_o one_o think_v it_o improper_a or_o absurd_a to_o assert_v prove_v that_o these_o vessel_n do_v thus_o terminate_v as_o if_o it_o be_v in_o small_a glandule_n let_v he_o but_o consider_v what_o a_o gland_n be_v and_o how_o it_o be_v compose_v and_o he_o will_v not_o think_v the_o conclusion_n irrational_a for_o a_o gland_n be_v nothing_o else_o be_v but_o a_o composition_n of_o a_o infinite_a number_n of_o small_a and_o diminutive_a vessel_n several_a and_o most_o of_o which_o have_v communication_n one_o with_o another_o which_o gland_n so_o compose_v be_v as_o a_o storehouse_n to_o receive_v and_o contain_v a_o certain_a liquor_n till_o necessity_n require_v or_o its_o quantity_n cause_v a_o exclusion_n of_o it_o and_o this_o seem_v plain_o to_o be_v favour_v by_o dr._n ridley_n when_o he_o say_v that_o the_o whole_a body_n be_v a_o continuity_n of_o vessel_n ad_fw-la infinitum_fw-la now_o if_o a_o gland_n consist_v of_o a_o infinite_a number_n of_o small_a vessel_n and_o if_o the_o branch_n of_o nerve_n vein_n and_o artery_n be_v divide_v before_o they_o terminate_v into_o a_o innumerable_a number_n of_o most_o invisible_a twig_n as_o be_v most_o certain_a when_o from_o one_o twig_n of_o each_o sort_n be_v derive_v a_o vast_a number_n and_o all_o these_o so_o derive_v be_v mix_v and_o interweave_v one_o with_o another_o why_o may_v we_o not_o say_v at_o least_o metaphorical_o since_o they_o in_o their_o distribution_n imitate_v the_o composition_n of_o gland_n that_o they_o terminate_v in_o small_a glandule_n some_o perhaps_o will_v ask_v how_o must_v we_o discover_v these_o gland_n malpigius_n have_v observe_v the_o liver_n to_o be_v compose_v of_o cluster_n of_o gland_n hang_v at_o the_o extremity_n of_o the_o large_a vessel_n like_v so_o many_o bunch_n of_o grape_n and_o the_o gland_n in_o other_o part_n be_v apparent_a but_o in_o a_o muscle_n we_o can_v discern_v no_o such_o thing_n for_o it_o especial_o when_o boil_v part_n into_o distinct_a carnous_a fiber_n to_o which_o i_o answer_v discern_v that_o those_o gland_n be_v nothing_o else_o but_o a_o composition_n of_o the_o end_n of_o import_v and_o export_v vessel_n and_o the_o reason_n why_o we_o can_v discern_v the_o same_o in_o a_o muscle_n be_v this_o because_o the_o extremity_n of_o the_o vessel_n be_v so_o fine_a and_o consequent_o so_o brittle_a and_o be_v contain_v in_o the_o interstice_n of_o so_o strong_a and_o firm_a fiber_n that_o whenever_o we_o endeavour_v a_o separation_n of_o the_o fiber_n the_o glandule_n be_v tear_v away_o from_o the_o vessel_n from_o which_o they_o be_v derive_v whereas_o the_o fiber_n which_o run_v transverse_v the_o liver_n easy_o crumble_v away_o be_v much_o more_o weak_a and_o less_o numerous_a the_o reason_n why_o the_o muscular_a fiber_n be_v so_o much_o strong_a than_o those_o that_o run_v through_o the_o liver_n be_v apparent_a enough_o viz._n because_o the_o former_a be_v the_o instrument_n of_o motion_n and_o consequent_o there_o lie_v a_o great_a stress_n of_o they_o than_o on_o the_o latter_a which_o serve_v to_o make_v the_o part_n a_o little_a more_o compact_a and_o to_o keep_v the_o outward_a coat_n from_o be_v loose_a upon_o its_o circumference_n now_o because_o it_o be_v impossible_a to_o separate_v and_o remove_v these_o muscular_a fiber_n so_o as_o to_o leave_v the_o sanguiferous_a vessel_n as_o entire_a as_o will_v be_v requisite_a for_o the_o exact_a and_o certain_a discovery_n of_o their_o termination_n and_o because_o it_o be_v certain_a that_o these_o vessel_n be_v divide_v and_o subdivide_v ad_fw-la minimum_fw-la that_o they_o be_v interweave_v one_o with_o another_o and_o that_o a_o gland_n be_v nothing_o else_o but_o a_o composition_n of_o vessel_n we_o may_v rational_o conclude_v they_o all_o terminate_v in_o diminutive_a gland_n the_o nerve_n vein_n and_o artery_n compose_v and_o end_v in_o these_o gland_n i_o shall_v next_o inquire_v to_o what_o end_n they_o do_v all_o thus_o meet_v together_o the_o use_n of_o the_o nerve_n in_o these_o be_v the_o same_o as_o in_o other_o part_n nerve_n viz._n to_o convey_v a_o spirituo-saline_a liquor_n from_o the_o brain_n which_o spirit_n be_v volatile_a and_o apt_a to_o ferment_n when_o mix_v with_o a_o liquor_n of_o a_o contrary_a nature_n be_v continual_o send_v by_o the_o systole_n of_o the_o brain_n into_o all_o the_o muscle_n of_o the_o body_n and_o be_v lay_v down_o forcible_o in_o the_o aforesaid_a diminutive_a gland_n gland_n do_v there_o meet_v with_o arterious_a blood_n drive_v in_o by_o every_o contraction_n of_o the_o heart_n which_o two_o liquor_n strong_o ferment_v together_o the_o animal_n spirit_n do_v by_o a_o attrition_n subtilise_fw-fr attenuate_v and_o rarify_v those_o particle_n of_o the_o succus_fw-la nutritius_n supply_v from_o the_o mass_n of_o blood_n by_o which_o mean_v their_o own_o be_v much_o dull_v and_o become_v less_o active_a for_o the_o future_a and_o by_o a_o mixture_n of_o these_o animal_n spirit_n with_o the_o rarefy_v succus_fw-la nutritius_n result_v a_o liquor_n different_n from_o succus_fw-la and_o of_o a_o middle_a state_n betwixt_o the_o animal_n spirit_n and_o the_o