the_o disease_n or_o temperament_n of_o the_o person_n to_o who_o they_o offer_v it_o what_o thing_n can_v be_v more_o absurd_a and_o fantastical_a then_o to_o minister_v one_o &_o the_o self_n same_o remedy_n to_o contrary_a &_o repugnant_a affect_n hot_a &_o cold_a dry_a and_o moist_a empty_a and_o replete_a acute_a and_o cronicall_a which_o for_o the_o more_o part_n have_v deep_a root_n and_o be_v of_o long_a continuance_n then_o can_v sudden_o be_v blow_v away_o with_o a_o puff_n of_o a_o smoky_a tobacco_n pipe_n yea_o &_o some_o of_o they_o can_v hardly_o be_v remove_v by_o the_o great_a pain_n care_n &_o cunning_a of_o the_o expert_a and_o learned_a in_o physic_n for_o none_a in_o medico_fw-la semper_fw-la relevetur_fw-la ut_fw-la aeger_fw-la interdum_fw-la docta_fw-la plus_fw-la valet_fw-la arte_fw-la malum_fw-la and_o yet_o these_o tobacco_n 11._o sauâ—rits_n hold_v no_o disease_n so_o incurable_a but_o that_o in_o some_o measure_n it_o receive_v either_o cure_n or_o ease_v by_o this_o tobacco_n but_o i_o assure_v you_o many_o disease_n be_v of_o themselves_o and_o their_o own_o nature_n light_n and_o of_o easy_a cure_n may_v by_o the_o untimely_a use_n of_o this_o same_o become_v altogether_o incurable_a such_o be_v the_o first_o step_n or_o degree_n to_o a_o heticke_a distemper_n of_o heat_n in_o the_o liver_n oppilation_n of_o the_o lung_n and_o such_o like_a and_o true_o if_o nothing_o else_o shall_v make_v one_o out_o of_o fancy_n with_o the_o use_n of_o tobacco_n it_o may_v be_v sufficient_a for_o a_o equal_a judge_n to_o think_v with_o himself_o how_o unnatural_a a_o thing_n it_o be_v to_o pervert_v the_o natural_a use_n &_o office_n of_o the_o part_n of_o the_o body_n for_o by_o the_o force_n of_o tobacco_n the_o mouth_n throat_n and_o stomach_n appoint_v by_o nature_n for_o the_o receipt_n of_o food_n &_o nourishment_n for_o the_o whole_a body_n be_v make_v emunctuary_n cleanse_v place_n and_o sink_n supply_v herein_o the_o office_n of_o the_o most_o abject_a and_o base_a part_n for_o the_o filth_n and_o superfluous_a excrement_n of_o the_o whole_a body_n the_o second_o reason_n the_o second_o reason_n against_o the_o ordinary_a use_n of_o tobacco_n be_v take_v from_o the_o excess_n of_o his_o two_o manifest_a quality_n of_o heat_n and_o dri'th_n which_o monardus_n and_o other_o also_o have_v affirm_v to_o come_v near_o to_o the_o three_o degree_n of_o excess_n in_o either_o quality_n so_o that_o if_o man_n of_o hot_a and_o dry_a constitution_n shall_v often_o use_v the_o feume_n of_o tobacco_n no_o doubt_n they_o shall_v increase_v much_o their_o distemper_n for_o like_v add_v to_o his_o like_a increase_v the_o resemblance_n &_o similitude_n the_o more_o according_a to_o that_o axiom_n in_o philosophy_n 〈◊〉_d omnes_fw-la unile_fw-la additum_fw-la simili_fw-la reddia_fw-la ipsum_fw-la magis_fw-la simile_n whereupon_o aristotle_n in_o his_o 8._o book_n and_o 29._o chap._n animal_n de_fw-fr animalibus_fw-la infer_v that_o a_o snake_n if_o he_o eat_v of_o a_o scorpion_n wax_v far_o more_o venomous_a than_o he_o be_v before_o but_o i_o need_v not_o to_o stand_v long_o upon_o this_o point_n see_v that_o daily_a practice_n &_o experience_n teachth_n we_o that_o heat_n increase_v heat_n &_o thing_n cold_a do_v increase_n in_o we_o a_o greaer_fw-mi cold_n the_o like_a may_v be_v say_v of_o the_o other_o quality_n of_o dri'th_n and_o moisture_n so_o that_o in_o natural_a reason_n and_o common_a sense_n it_o seem_v true_a that_o the_o extreme_a &_o violent_a dri'th_n &_o heat_n of_o tobacco_n make_v it_o far_o unfit_a &_o unwholesome_a for_o thin_a &_o choleric_a body_n and_o so_o be_v it_o also_o for_o youth_n and_o such_o as_o grow_v for_o qui_fw-la crescunt_fw-la plurimum_fw-la habent_fw-la innaticaloris_fw-la this_o natural_a heat_n in_o youth_n by_o the_o immoderate_a use_n of_o this_o fiery_a fume_n will_v soon_o turn_v unto_o a_o heat_n unnatural_a and_o thereby_o be_v occasion_n of_o infinite_a malady_n but_o i_o hold_v it_o a_o thing_n very_o dangerous_a not_o only_o for_o the_o young_a sort_n but_o also_o for_o all_o other_o age_n and_o constitution_n whatsoever_o to_o be_v over_o bold_a with_o tobacco_n for_o it_o do_v not_o only_o consume_v and_o dissipate_v natural_a heat_n in_o they_o by_o increase_v of_o the_o unnatural_a but_o it_o waste_v also_o &_o dry_v up_o radical_a moisture_n the_o principal_a subject_n of_o native_a heat_n so_o that_o hereof_o ensue_v in_o the_o body_n great_a store_n of_o crud_a &_o undigested_a humour_n the_o effect_n of_o immoderate_a heat_n in_o us._n for_o it_o be_v not_o fiery_a nor_o immoderate_a heat_n in_o we_o but_o rather_o a_o mild_a &_o unctuous_a warmth_n consist_v in_o a_o temtperate_a &_o moderate_a moisture_n that_o perform_v as_o well_o concoction_n as_o all_o other_o natural_a action_n in_o us._n which_o thing_n be_v very_o apparent_a &_o conspicuous_a in_o such_o as_o be_v afflict_v with_o hot_a &_o burn_a fever_n in_o who_o as_o the_o fiery_a heat_n appear_v most_o so_o crude_a and_o undigested_a humour_n do_v abound_v more_o then_o in_o such_o as_o be_v clear_a of_o such_o extremity_n of_o heat_n neither_o do_v their_o humour_n at_o any_o time_n come_v to_o perfect_a digestion_n in_o they_o until_o the_o rigour_n and_o violence_n of_o that_o fiery_a heat_n be_v in_o some_o sort_n by_o cool_a diet_n and_o medicine_n repress_v much_o less_o therefore_o be_v the_o patron_n of_o tobacco_n to_o be_v beeleeve_v in_o this_o that_o hot_a and_o burn_a ague_n rise_v of_o corruption_n and_o putrefaction_n of_o choler_n &_o blood_n in_o the_o vein_n or_o about_o the_o principal_a part_n of_o man_n body_n may_v be_v cure_v with_o a_o infusion_n of_o tobacco_n lease_n in_o white_a wine_n steep_v all_o night_n for_o as_o it_o be_v ever_o a_o aphorism_n &_o maxim_n in_o physic_n that_o as_o like_a be_v maintain_v by_o his_o like_a so_o be_v it_o also_o of_o like_a certainty_n in_o the_o same_o art_n that_o contrâ—ria_n a_o contrarijs_fw-la currantur_fw-la contrary_n be_v cure_v by_o their_o contrary_n i_o mean_v contrary_a rather_o to_o the_o disease_n or_o to_o the_o cause_n of_o the_o disease_n but_o what_o contrariety_n i_o pray_v you_o can_v be_v find_v between_o tobacco_n and_o a_o fever_n tercian_n or_o burn_a ague_n when_o as_o they_o manifest_o agree_v in_o their_o principal_a quality_n of_o heat_n and_o dri'th_n both_o equal_o fall_v in_o excess_n of_o either_o of_o they_o the_o like_a may_v be_v say_v of_o other_o effect_n proceed_v of_o the_o same_o of_o like_a cause_n but_o to_o let_v the_o disease_a pass_n and_o to_o come_v to_o those_o which_o be_v of_o perfect_a health_n i_o take_v it_o very_o dangerous_a and_o hurtful_a for_o they_o often_o to_o use_v this_o 〈…〉_z for_o thereby_o great_a part_n of_o that_o humour_n be_v dissipate_v waste_v spend_v &_o cast_v forth_o of_o the_o body_n by_o often_o 〈◊〉_d siege_n sweat_v and_o continnall_a spitting_n and_o coughing_n which_o in_o process_n of_o time_n will_v turn_v to_o good_a blood_n and_o wholesome_a nurrishment_n for_o the_o body_n for_o crude_a and_o waterish_a humour_n which_o for_o the_o most_o part_n be_v all_o those_o which_o by_o this_o medicine_n be_v be_v oftentimes_o very_o necessary_a for_o many_o use_n in_o the_o body_n as_o for_o pliant_a motion_n of_o the_o loint_n and_o principal_o for_o nurrishment_n of_o the_o phlegmatic_a and_o cold_a part_n and_o it_o be_v a_o receive_a opinion_n among_o the_o best_a physician_n that_o nature_n be_v a_o provident_a &_o careful_a nurse_n of_o mankind_n have_v purposely_o leave_v this_o crudie_a humour_n in_o our_o body_n to_o the_o intent_n that_o we_o may_v ever_o have_v some_o thing_n in_o store_n to_o nourish_v we_o if_o happy_o we_o shall_v at_o any_o time_n want_v other_o food_n but_o that_o no_o small_a part_n of_o our_o nourishment_n be_v draw_v away_o by_o the_o untimely_a use_n of_o this_o tobacco_n nourishment_n may_v manifest_o appear_v by_o those_o man_n who_o before_o the_o use_n thereof_o be_v gross_a and_o foggy_a but_o after_o they_o have_v acquaint_v themselves_o with_o this_o kind_n of_o practice_n they_o become_v very_o lean_a and_o sâ—lender_a so_o that_o no_o doubt_n if_o they_o desist_v not_o in_o time_n from_o far_a use_n thereof_o there_o be_v no_o small_a suspicion_n lest_o that_o they_o shall_v thereby_o fall_v into_o consumption_n &_o to_o that_o of_o the_o most_o dangerous_a sort_n call_v of_o the_o physician_n marasmos_n procede_v of_o want_n of_o substantial_a nurrishment_n &_o dissipation_n of_o natural_a heat_n and_o decay_v of_o spirit_n in_o the_o body_n and_o herein_o i_o can_v but_o wonder_n much_o at_o the_o over_o sight_n of_o some_o who_o otherwise_o be_v learned_a and_o wise_a yet_o in_o this_o seem_v very_o paradoxical_a when_o as_o they_o contend_v to_o prove_v tobacco_n to_o be_v a_o great_a nurrisher_n for_o beside_o
viper_n and_o how_o they_o differ_v from_o the_o other_o serpent_n call_v dipsas_n because_o say_v he_o they_o be_v expert_a and_o cunning_a in_o they_o so_o that_o it_o be_v manifest_a &_o apparent_a by_o the_o testimony_n before_o rehearse_v nature_n that_o custom_n may_v alter_v &_o change_v nature_n and_o the_o quality_n of_o thing_n according_a to_o that_o usual_a consuetude_n alter_v a_o naturam_fw-la custom_n change_v nature_n &_o at_o length_n turn_v into_o nature_n itself_o for_o it_o be_v a_o other_o nature_n the_o like_a be_v see_v in_o the_o east_n indies_n where_o the_o turk_n familiar_o use_v opium_n in_o large_a quantity_n which_o to_o we_o but_o in_o very_o small_a dose_n be_v experiment_a to_o be_v manifest_a poison_n only_o long_a use_n &_o familiar_a practice_n have_v make_v this_o unconuenient_a for_o their_o body_n and_o so_o no_o doubt_n if_o our_o country_n man_n from_o their_o infancy_n have_v by_o little_a and_o little_o use_v to_o take_v this_o tobacco_n fume_n or_o other_o poison_n whatsoever_o they_o shall_v have_v have_v as_o little_a cause_n to_o fear_v the_o danger_n thereof_o as_o the_o turk_n have_v of_o their_o opium_n or_o the_o old_a marsitian_n have_v of_o viper_n or_o the_o west_n indian_n have_v of_o their_o tobacco_n but_o for_o want_v of_o that_o custom_n it_o fare_v with_o we_o in_o that_o sort_n that_o if_o we_o take_v any_o great_a quantity_n of_o the_o opium_n before_o specify_v we_o shall_v rather_o die_v on_o the_o sudden_a or_o else_o fall_v into_o that_o kind_n of_o dead_a sleep_n as_o that_o we_o shall_v by_o no_o other_o mean_n then_o by_o the_o archangel_n trumpet_n sound_v at_o the_o latter_a day_n be_v awaken_v thereout_o to_o this_o may_v be_v add_v a_o secret_a virtue_n and_o specifical_a quality_n give_v the_o indian_n by_o nature_n whereby_o they_o be_v not_o overcome_v by_o this_o kind_n of_o poison_n as_o other_o nation_n be_v for_o sextus_n empericus_n empericus_n report_v in_o the_o like_a case_n that_o one_o attienagoras_n argivus_n have_v a_o gift_n give_v by_o nature_n even_o from_o his_o birth_n that_o he_o can_v be_v hurt_v by_o no_o venomous_a beast_n or_o serpent_n whatsoever_o and_o that_o certain_a people_n of_o aethiopia_n do_v natural_o feed_v &_o nourish_v themselves_o with_o the_o flesh_n of_o scorpion_n but_o we_o englishman_n may_v not_o safe_o presume_v that_o this_o specifical_a virtue_n &_o hide_a quality_n do_v abide_v or_o lurk_v in_o we_o see_v that_o by_o far_o weak_a poison_n than_o these_o we_o sustain_v infinite_a peril_n and_o often_o incur_v death_n itself_o wherefore_o we_o have_v the_o less_o cause_n to_o venture_v on_o thing_n in_o reason_n suspect_v to_o be_v of_o a_o venomous_a &_o poison_a quality_n because_o forsooth_o the_o indian_n do_v it_o without_o offence_n neither_o be_v it_o of_o any_o great_a weight_n or_o moment_n which_o be_v allege_v of_o the_o tobacco_n patron_n for_o her_o commendation_n that_o mariner_n and_o seafaring_a man_n never_o find_v any_o remedy_n so_o forceable_a against_o the_o scurvy_a and_o other_o disease_n of_o like_a nature_n common_o incident_a to_o that_o kind_n of_o people_n by_o mean_n of_o the_o foggy_a air_n in_o the_o sea_n and_o their_o unwholesome_a diet_n then_o be_v the_o fume_n of_o tobacco_n the_o reason_n of_o this_o profit_n in_o mariner_n may_v be_v because_o their_o body_n after_o long_o lie_v on_o the_o sea_n be_v fill_v and_o stuff_v with_o bad_a and_o corrupt_a humour_n on_o the_o which_o the_o force_n and_o power_n of_o tobacco_n do_v work_v draw_v and_o purge_v they_o forth_o of_o the_o body_n no_o otherwise_o then_o other_o strong_a purge_n expel_v and_o purge_v forth_o such_o corrupt_a humour_n as_o have_v any_o similitude_n or_o likeness_n to_o themselves_o but_o as_o strong_a purge_v take_v of_o sound_n and_o wholesome_a body_n as_o i_o show_v you_o before_o be_v very_o perilous_a and_o dangerous_a so_o true_o be_v tobacco_n be_v take_v of_o such_o as_o be_v clear_a and_o void_a of_o such_o impure_a and_o corrupt_a matter_n which_o to_o the_o mariner_n be_v most_o familiar_a and_o usual_a the_o like_a be_v see_v of_o other_o poison_n which_o when_o they_o find_v any_o of_o their_o own_o quality_n &_o nature_n in_o man_n body_n or_o that_o have_v any_o likeness_n or_o similitude_n to_o they_o they_o draw_v forth_o the_o same_o the_o like_a coveâ—ing_v his_o like_a and_o leave_v the_o sound_n and_o healthy_a humour_n clear_a and_o unspotted_a but_o when_o no_o such_o poison_a matter_n be_v find_v in_o the_o body_n then_o do_v the_o poison_n or_o venom_n receive_v work_n on_o the_o good_a humour_n utter_o corrupt_v and_o destroy_v they_o so_o that_o it_o be_v apparent_a that_o sometime_o venom_v to_o venomous_a and_o poison_a person_n may_v be_v profitable_a &_o medicinable_a but_o to_o sound_v &_o healthy_a body_n they_o can_v never_o happen_v without_o danger_n the_o seven_o reason_n the_o seven_o reason_n against_o tobacco_n be_v that_o this_o herb_n seem_v to_o be_v first_o find_v out_o and_o invent_v by_o the_o devil_n and_o first_o use_v and_o practise_v by_o the_o devil_n priest_n and_o therefore_o not_o to_o be_v use_v of_o we_o christian_n that_o the_o devil_n be_v the_o first_o author_n hereof_o monardus_n in_o his_o treatise_n of_o tobacco_n do_v sufficient_o witness_v say_v the_o indian_a priest_n who_o no_o doubt_n be_v instrument_n of_o the_o devil_n who_o they_o serve_v do_v ever_o before_o they_o answer_v to_o question_n propound_v to_o they_o by_o their_o prince_n drink_v of_o this_o tobacco_n fume_n with_o the_o vigour_n and_o strength_n whereof_o they_o fall_v sudden_o to_o the_o ground_n as_o dead_a man_n remain_v so_o according_a to_o the_o quantity_n of_o the_o smoke_n that_o they_o have_v take_v and_o when_o the_o herb_n have_v do_v his_o work_n they_o revive_v and_o wake_v give_v answer_n according_a to_o the_o vision_n and_o illusion_n which_o they_o see_v whilst_o they_o be_v wrap_v in_o that_o order_n and_o they_o interpret_v their_o demand_n as_o to_o they_o seem_v best_a or_o as_o the_o devil_n have_v counsel_v they_o give_v continual_a doubtful_a answer_n in_o such_o sort_n that_o howsoever_o they_o fall_v out_o they_o may_v turn_v it_o to_o their_o purpose_n like_v unto_o the_o oracle_n of_o apollo_n as_o aio_fw-la te_fw-la aeacide_n romanos_fw-la vincere_fw-la posse_fw-la which_o may_v be_v understand_v that_o either_o he_o may_v overthrow_v the_o roman_n or_o that_o the_o roman_n may_v overcome_v he_o but_o yet_o in_o more_o plain_a word_n the_o same_o monardusâ—_n little_a after_o declare_v the_o devil_n to_o be_v the_o author_n of_o tobacco_n and_o of_o the_o knowledge_n thereof_o say_v and_o as_o the_o devil_n be_v a_o deceiver_n and_o have_v the_o knowledge_n of_o the_o virtue_n of_o herb_n so_o he_o do_v show_v they_o the_o virtue_n of_o this_o herb_n by_o mean_n whereof_o they_o may_v see_v the_o imagination_n and_o vision_n that_o he_o represent_v unto_o they_o and_o by_o that_o mean_n do_v deceive_v they_o wherefore_o in_o my_o opinion_n this_o practice_n be_v the_o more_o to_o be_v eschew_v of_o we_o christian_n who_o follow_v &_o profess_v christ_n as_o the_o only_a verity_n and_o truth_n and_o detest_v and_o abhor_v the_o devil_n as_o a_o liar_n and_o deceiver_n of_o mankind_n the_o eight_o and_o last_o reason_n the_o last_o and_o that_o not_o the_o least_o argument_n against_o tobacco_n be_v that_o it_o be_v a_o great_a encreaser_n of_o melancholy_n in_o we_o and_o thereby_o dispose_v our_o body_n to_o all_o melancholy_a impression_n and_o effect_n proceed_v of_o that_o humour_n galen_n in_o his_o second_o book_n of_o temperament_n and_o 3._o chapter_n 3._o define_v melancholy_a to_o be_v the_o very_a sediment_n and_o dregs_n of_o blood_n which_o be_v so_o far_o thick_a &_o cold_a than_o blood_n as_o yellow_a choler_n be_v hold_v to_o be_v thin_a and_o hot_a than_o the_o same_o and_o this_o melancholy_a humour_n be_v say_v to_o be_v of_o two_o sort_n the_o one_o natural_a the_o other_o unnatural_a the_o natural_a be_v that_o thick_a part_n of_o the_o blood_n before_o rehearse_v the_o unnatural_a be_v not_o the_o sediment_n or_o ground_n of_o good_a blood_n but_o rather_o a_o certain_a burn_v and_o parch_a matter_n rise_v of_o the_o adustian_n and_o scorch_a of_o the_o other_o humour_n that_o be_v of_o phlegm_n yellow_a choler_n and_o of_o the_o former_a sediment_n of_o pure_a blood_n which_o we_o term_v natural_a melancholy_n and_o albeit_o it_o seem_v very_o unlike_o that_o phlegm_n be_v of_o nature_n cold_a and_o moist_a may_v be_v any_o adustian_n be_v turn_v into_o swoart_n and_o black_a choler_n yet_o in_o quality_n and_o disposition_n that_o humour_n do_v often_o represent_v and_o resemble_v melancholy_n itself_o and_o therefore_o galen_n hold_v sometime_o melancholy_a to_o be_v engender_v of_o phlegmy_a
over-hardned_a and_o dry_a the_o contrariety_n and_o diversity_n of_o these_o unnatural_a melancholy_n do_v hang_v and_o depend_v on_o the_o contrariety_n and_o difference_n of_o the_o humour_n whereof_o they_o be_v engender_v all_o these_o sort_n of_o melancholy_n be_v augment_v and_o increase_v much_o in_o such_o as_o often_o accustom_v themselves_o to_o the_o fume_n of_o tobacco_n for_o first_o touch_v the_o natural_a melancholy_n it_o be_v manifest_a that_o the_o thick_a and_o grosser_n that_o the_o blood_n be_v the_o more_o of_o that_o thick_a and_o earthly_a sediment_n it_o shall_v contain_v but_o tobacco_n thicken_v and_o engross_v the_o blood_n and_o therefore_o tobacco_n engender_v in_o we_o a_o great_a store_n of_o that_o thick_a and_o gross_a sediment_n which_o we_o define_v to_o be_v of_o galen_n call_v natural_a melancholy_n the_o mayor_n or_o first_o proposition_n be_v manifest_a for_o all_o liquid_a and_o moist_a thing_n be_v the_o more_o thick_a or_o thin_a and_o clear_a according_a to_o the_o quantity_n of_o the_o ground_n and_o fece_n mix_v in_o the_o same_o for_o if_o the_o ground_n be_v many_o then_o be_v the_o matter_n or_o humour_n troublesome_a and_o thick_a but_o if_o the_o dregs_n or_o fece_n be_v few_o then_o be_v the_o humour_n clear_a and_o thin_a the_o minor_a or_o second_o proposition_n of_o the_o former_a sillogisme_n may_v be_v prove_v in_o this_o sort_n all_o those_o thing_n which_o waste_n and_o consume_v the_o pure_a &_o thin_a part_n of_o the_o blood_n do_v cause_n the_o same_o blood_n to_o remain_v afterward_o more_o gross_a and_o thick_a and_o therefore_o may_v just_o be_v say_v to_o thicken_v the_o blood_n but_o tobacco_n waste_v and_o absume_v the_o liquid_a and_o thin_a part_n of_o our_o blood_n and_o therefore_o tobacco_n may_v just_o be_v say_v to_o thicken_v the_o same_o the_o mayor_n proposition_n be_v evident_a need_v no_o far_a proof_n the_o minor_a be_v prove_v by_o daily_a and_o usual_a practice_n and_o experience_n of_o such_o as_o common_o do_v drink_v this_o tobacco_n for_o thereby_o do_v they_o purge_v great_a store_n of_o a_o clear_a and_o thin_a humour_n which_o will_v mix_v itself_o with_o the_o blood_n and_o cause_v the_o same_o to_o be_v more_o liquid_a and_o fluent_a and_o in_o time_n also_o by_o good_a concoction_n turn_v into_o pure_a and_o subtle_a blood_n apt_a to_o feed_v and_o nourish_v the_o body_n and_o albeit_o melancholy_a be_v of_o nature_n cold_a seem_v to_o have_v no_o need_n of_o phlegmetique_n and_o thin_a humour_n to_o be_v mix_v therewith_o lest_o that_o his_o cold_a distemper_n be_v great_o increase_v thereby_o yet_o of_o necessity_n some_o store_n of_o this_o crude_a and_o raw_a matter_n be_v require_v to_o run_v with_o the_o melancholy_a juice_n to_o moderate_v and_o temper_v his_o extreme_a siccetie_n and_o drythe_o and_o to_o defend_v it_o from_o induration_n &_o hardness_n the_o increase_n whereof_o in_o our_o body_n breed_v dulness_n sottishness_n and_o blockishness_n all_o which_o be_v the_o usual_a effect_n of_o over-hardened_n and_o dry_a melancholy_n for_o melancholy_a over-hardened_n if_o it_o come_v once_o to_o be_v cool_v it_o be_v extreme_a cold_a as_o iron_n which_o be_v heat_n be_v extreme_a hot_a and_o be_v cool_v again_o be_v extreme_a cold_a also_o so_o this_o hard_a and_o dry_a melancholy_n once_o deprive_v of_o natural_a heat_n by_o the_o inordinate_a use_n of_o tobacco_n fume_n the_o fiery_a heat_n of_o the_o one_o dissipate_v the_o natural_a and_o lesser_a heat_n of_o the_o other_o can_v yield_v nothing_o else_o but_o the_o effect_n of_o a_o excessive_a and_o immoderate_a cold_a cause_n lie_v in_o the_o vein_n and_o mix_v with_o the_o blood_n such_o be_v esteem_v to_o be_v dulness_n of_o conceit_n blockishness_n mopishnesse_n and_o sottishness_n one_o of_o the_o worst_a kind_n of_o accident_n that_o common_o ensue_v over-hardened_n cool_v and_o dry_v melancholy_a in_o our_o body_n again_o such_o as_o the_o part_n of_o the_o blood_n be_v such_o also_o be_v think_v the_o blood_n to_o be_v and_o as_o the_o blood_n prove_v so_o likewise_o be_v the_o spirit_n affect_v for_o they_o do_v issue_n and_o proceed_v from_o the_o blood_n itself_o and_o such_o as_o the_o spirit_n be_v such_o also_o be_v adjudge_v to_o be_v the_o temper_n and_o dissipation_n of_o the_o heart_n and_o brain_n and_o as_o the_o brain_n be_v dispose_v and_o affect_v so_o likewise_o be_v the_o virtue_n of_o conceit_n imagination_n understanding_n and_o remembrance_n affect_v and_o dispose_v also_o all_o which_o in_o particular_a by_o sundry_a example_n be_v easy_a to_o prove_v for_o he_o that_o be_v but_o mean_o see_v and_o slender_o read_v in_o philosophy_n say_n that_o the_o sanguine_a man_n by_o mean_n of_o the_o purity_n of_o his_o blood_n have_v his_o brain_n and_o inward_a part_n well_o temper_v his_o sense_n clear_a his_o spirit_n light_n and_o subtle_a his_o heart_n bold_a and_o merry_a his_o mind_n affable_a courteous_a and_o civil_a whereas_o on_o the_o contrary_a part_n the_o melancholy_a person_n by_o reason_n of_o the_o superfluous_a earthly_a and_o dry_a matter_n mix_v with_o his_o blood_n have_v his_o complexion_n more_o wan_a and_o swart_a his_o conceit_n of_o brain_n more_o dull_a and_o hard_a his_o mind_n give_v to_o sollitarinesse_n and_o private_a life_n for_o those_o two_o humour_n of_o blood_n and_o melancholy_n be_v in_o both_o their_o quality_n very_o repugnant_a and_o contrary_a the_o one_o be_v hot_a and_o moist_a the_o other_o cold_a and_o dry_a but_o here_o i_o think_v i_o hear_v you_o say_v what_o make_v this_o idle_a discourse_n of_o blood_n and_o melancholy_n of_o the_o disposition_n of_o the_o brain_n and_o spirit_n to_o your_o purpose_n or_o to_o the_o reputation_n of_o tobacco_n forsooth_o very_o much_o for_o hereby_o it_o appear_v that_o the_o continual_a practice_n of_o tobacco_n destroy_v the_o purity_n and_o clearness_n of_o their_o blood_n in_o that_o as_o i_o prooâ—ed_v before_o it_o harden_v and_o thicken_v the_o same_o and_o in_o thicken_a it_o engender_v dull_a &_o melancholy_a spirit_n which_o make_v blockish_a and_o sottish_a conceit_n and_o a_o timorous_a and_o deject_a mind_n not_o fit_a or_o convenient_a for_o man_n that_o delilght_v in_o civility_n and_o society_n of_o other_o for_o see_v that_o the_o fume_n of_o tobacco_n yield_v no_o good_a food_n or_o nourishment_n to_o the_o pure_a blood_n but_o rather_o trouble_v and_o corrupt_v the_o same_o it_o be_v thereby_o most_o plain_a and_o evident_a that_o it_o engender_v in_o we_o most_o dull_a and_o trouble_a spirit_n also_o taste_v and_o savour_v much_o of_o that_o loathsome_a fume_n and_o duskish_a smoke_n which_o riseâ—â—_n &_o steem_v up_o to_o the_o brain_n by_o the_o roof_n and_o pallate_n of_o the_o mouth_n first_o send_v thither_o through_o the_o tobacco_n pipe_n full_o charge_v with_o tobacco_n dust_n and_o afterward_o scorch_v and_o incinerate_v by_o the_o extreme_a heat_n of_o the_o parch_a fire_n this_o dark_a and_o smoky_a fume_n pierce_n the_o cavity_n and_o ventricle_n of_o the_o brain_n no_o otherwise_o than_o a_o melancholy_a wind_n or_o adust_a vapour_n rise_v from_o a_o adust_a liver_n or_o obstruct_a spleen_n do_v breed_v in_o we_o terror_n and_o fear_v discontentment_n of_o life_n false_a and_o perverse_a imagination_n and_o fantasy_n most_o strange_a no_o way_n depend_v upon_o just_a cause_n or_o ground_n and_o always_o a_o melancholy_a spirit_n a_o fertfull_a and_o timorous_a mind_n for_o true_o the_o inward_a darkness_n and_o obscurity_n of_o the_o brain_n do_v appall_v and_o terrify_v our_o inward_a sense_n and_o mind_n also_o in_o no_o less_o sort_n than_o do_v the_o external_a darkness_n or_o mist_n of_o the_o outward_a air_n terrify_v &_o appall_v the_o same_o and_o if_o any_o man_n be_v far_o blind_v with_o tobacco_n that_o he_o will_v not_o admit_v for_o true_a that_o the_o vapour_n or_o fume_n thereof_o ascend_v to_o the_o brain_n be_v dark_a and_o swart_a of_o colour_n and_o of_o quality_n excessive_a dry_a let_v he_o but_o cast_v his_o eye_n on_o the_o smoke_n issue_v forth_o of_o the_o nostril_n of_o the_o tabacconist_n or_o to_o the_o smoky_a tincture_n leave_v in_o the_o tobacco_n pipe_n after_o the_o receipt_n thereof_o and_o he_o shall_v easy_o reclaim_v his_o error_n this_o swart_a &_o sottish_a tincture_n cleave_v so_o fast_o to_o the_o inward_a part_n of_o the_o pipe_n as_o hardly_o by_o any_o mean_v but_o by_o the_o extreme_a heat_n of_o the_o fire_n it_o may_v be_v clear_v from_o thence_o and_o no_o doubt_n the_o like_a impression_n do_v the_o same_o leave_n in_o our_o brain_n and_o in_o the_o cavity_n thereof_o so_o that_o the_o animal_n spirit_n engender_v in_o those_o place_n can_v no_o less_o but_o participate_v thereof_o savour_v of_o the_o same_o no_o otherwise_o then_o wine_n put_v into_o a_o unsavoury_a and_o