Tasts found in the Pancreatick Juyce doth not exclude its Acidity 58. The Effervescency between the Bile and the Pancreatick Juyce is demonstrated by Experiments ibid. What Effervescency may sometimes happen in the Sick 61. That there is a hot and cold Effervescency is evinced by Observations and Experiments ib. What Effervescency happeneth in the Sound 62. Wherefore the Effervescency is not perceived in the time of Health ibid. The Palpitation of the Heart 63. The first Vtility of the Intestinal Effervescency ibid. The Effects of diverse Effervescencies are propounded 65. The greater or lesser Affinity of Acids with things dissolved 66. The Reason is examined Why acids do more powerfully joyn themselves to these than other Liquors 67. How the Aliments in the Stomach differ from those in the Guts ibid. That the cause of that Mutation is to be ascribed to the Pancreatick Juyce or Bile p. 68. The white Colour of the Chyle from whence it proceeds 69. The Second Vtility of the Intestinal Effervescency ibid. An Objection against the Alleadged Vtility from the Effervescency 70. The Solution of that Objection ibid. The Separation of what Particles may happen by the sole Fermentation of the Aliments 71. What Particles of Aliments are necessary to Life ibid. The Vtility of the Intestinal Effervescency is farther described 72. The way whereby the more Subtile parts of the Humours penetrate to the Heart from the Intestines ibid. The Natural Consistency of the Blood from whence it proceeds 73. Whether or no the Pancreatick Juyce may afford a Ferment to the Stomach 74. For what reason the Pancreatick Juyce doth incrassate the Bile ibid. For what reason it attenuates the Bile 75. What the Pancreatick Juyce effects being well and what being ill disposed ibid. That the Pancreas is the cause of many Diseases is witnessed by famous Physitians 76. The Order of their Calling ibid. The Diseases where-with the Substance of the Pancreas is wont to be infested 77. The History of the Pancreas of Thuanus grown into an admirable Magnitude 78. That the Pancreas is not the Vicar or Helper of the Spleen 79. Various Abscesses of the Pancreas found in dead Bodies ibid. Cancer 80. The History of it concreted into a stony Hardness 81. Stones ibid. That all the Glandules are Obnoxious to Stones 82. That the Pineal Glandule is more frequently afflicted with Stones in France than in Holland ibid. That the Pancreaas doth not alwayes follow the evil Affections of the Liver or Spleen ib. The Vices of the Pancreatick Juyce 83. The Pancreatick Juyce wherefore more sparingly driven to the Intestines ibid. Why more copiously propelled to the Intestines 84. Why inequally divided into the Guts ibid. Why it may be more Fluid 85. Why more Viscid ibid. The Vices of the Pancreatick Juyce perceptible to the Tast ibid. the lesser Acidity of the Pancreatick Juyce from whence 86. It s Acidity increased from whence ibid. It s Salsity from whence ibid. The cause of Austerity is searched into 87. The Faults of the Pancreas what Functions they hurt 88. The Faults of the Pancreatick Juyce what Functions they hurt 89. If it be sent to the Guts in a lesser Quantity ib. If it be carryed to the Guts in a greater Quantity 90. If it be inequally moved to the Guts 92. If more Fluid ibid. If more Viscid 93. If it be less Acid. ibid. Running-Pain in the Left-side from whence it ariseth ibid. Wherefore Melancholy men are less subject to the Plague than Cholerick ibid. Why the Blood of those who are infected with the Plague will not Coagulate ibid. That Volatile Salts do make the Blood more fluid 94. That Acidity is the cause of the Blood Coagulating ibid. That an Acid is the best Preservative in the time of a Plague 95. That a more Acid Pancreatick Juyce is the cause of Cold in the Region of the Loynes 96. Of Pain and Torment of the Belly ib. Of Black and Eruginous Bile ibid. That the Spleen doth not generate Atra-Bilis 97. A rare Observation demonstrating to the Eye the Generating of Atra-Bilis ibid. The Pancreatick Juyce together with other Humours is joyntly examined ibid. What Effervescency is excited between a dull Pancreatick Juyce and a more sharp Bile 98. A more sharp Pancreatick Juyce meeting with a sharper Bile what it effecteth 99. What Effervescency is excited between a sharper Pancreatick Juyce and a more dull Bile 100. The Diseases arising from the Pancreatick Juyce 102. The cause of Intermitting Feavers to be ascribed to the Pancreas ibid. A more Acid Pancreatick Juyce the cause of the Gout 103. The cause of a great Appetite and Hunger ibid. The Cause of difficult Breathing and a dry Cough 104. The Cause of those outragious Epileptick Fits which the Dutch call Stuypiens 105. The Cause of Contraction of the Pulse and Swounding ibid. The cause of Convulsions 106. The cause of the Strangury 107. The cause of Malignant Vlcers ibid. The cause of the Adstriction of the Belly 108. The cause of Melancholy and Diseases from thence proceeding ibid. An Answer to an Objection That it cannot excite the Atra-Bilis 109. It is demonstrated by Examples that Acids may stir up divers Colours ibid. The reason thereof searched into 110. How Acidity may abound in their Bodies who are not conversant in the Vse of Acids 111. It is demonstrated that the austere Pancreatick Juyce may be the cause of the Suffocation of the Womb. 112. A wonderful Effect of the Pancreatick Juyce being tasted 113. That men do sometimes labour under the like Hysterick Suffocations ibid. The Cause and manner of the Generation of Mother Fits 114. The cause of the Hypocondriack Affection ib. A Salt Pancreatick Juyce is the cause of a Diarhaea ibid. How the Pancreatick Juyce is to be corrected 116. If it be effused more sparingly by reason of Viscidity or Obstruction ibid. If it flows more largely 117. Purgers Electively given ibid. Nothing of Excrement driven by the Purges through the Meseraick Arteries into the Instines 118. That Purging Medicaments may operate as happily by the Venae Lacteae ibid. The Correction of the over-fluid Pancreatick Juyce ibid. It s too much Acidity corrected 119. The Correction of its Austerity 120. It s Salsitude rectified ibid. The History of Agues or Intermitting Feavers 121. The Pathognomick Signe of a Feaver 122. The cause of a Feaver determined to be four-fold ibid. That there is a different cause of Continual and Intermitting Feavers 123. VVhat the Minera of Intermitting Feavers is 124. That it is not to be found in the Blood ibid. The Swiftness of the Bloods Circulation ib. That the Stagnation of the Blood cannot produce the cause of Intermitting Feavers ib. The cause and manner of the Generating of Inflamations ibid. That all the Humours described in the Schools are not to be found neither do they ever raise a manifest Effervescency 125. That the Focus of Intermitting Feavers hath been by many rightly sought in the Abdomen but ill ascribed to the Miseraick Veins the Duplicature of the Omentum the Intestine Colon c. ibid. The Focus of Intermitting Feavers to be ascribed to the Pancreas alone 127. The reason thereof examined ibid. An Objection against it answered ibid. That an Obstruction of the Ductus Pancreaticus is the cause of Intermitting Feavers 128. The Generation of an Obstruction in the Pancreatick Duct 129. The cause of the Fits access is the dissolution of that Obstruction 130. The Pancreatick Juyce accompanyed with Viscidity ibid. An Obstruction of the Pancreatick Duct found after Death in one who dyed of a Feaver 129. For what reason the Pancreatick Juyce groweth more sharp 130. In what manner it is made sharp and carryed to the Intestines and there effervesceth with the Humours 131. When that Effervescency may be called Feaverish ibid. The cause of a more frequent Preternatural Pulse ibid. The Division of Intermitting Feavers into Simple and Compound ibid. A Sub-division of the Simple into Quotidians Tertians Quartans c. 132. A Sub-division of the Compound according to the Feavors of which they are compounded ib. A Division of Intermitting Feavers into Cold and Burning ibid. The Essence of Intermitting Feavers consists not in Heat ibid. A Division of Intermitting Feavers according to their Symptomes 134. The reason of the return of the Fits sometimes daily other-while every Third or Fourth day ibid. The inequal Intermediate Space of Intermitting Feavers ibid. The cause of that Inequality 135. How long the Feaverish Fits may return and when wholly cease ibid. The cause of Intermitting Feavers both Simple and Compound 136. The reason of the same and of a diverse Species of Intermitting Feavers ibid. Why in Compound Intermitting Feavers the Fit of one doth precede supervene or follow the Fit of another 137. That Intermitting Feavers cannot proceed from an evil Diathesis of the Blood ibid. The reason why the Fits of Compound Feavers sometimes come sooner or later than their usual Hour 138. How Quotidians Double Tertians and Trible Quartans may be known ibid. The diversity of Heat and Cold of the Fits from whence 139. The cause of the Feaverish Heat and Cold inquired into ib. That acids are Cold and do produce Cold. ib. That the Bile exciteth Heat in the body 141. Why the Fits of Intermitting Feavers do usually began with Cold and Terminate with Heat ibid. Why Acid Vomitings and Belchings are rather to be deduced frrm the Pancreas than the Stomach 142. The Symptomes perceived in the Region of the Loynes in the time of the Cold Fit signifie the Male affection of the Pancreas 143. In what manner the Cure of Intermitting Feavers is to be performed 145. Medicaments tempering the Feverish Cold. ibid. Wherefore Medicines against the Feaver are to be exhibited in the very instant of the Fit 146. Medicaments tempering the Feaverish Heat 147. To asswage the Thirst ibid. When drink is to be allowed the Feaverish and when not 149. What Medicaments are to be given out of the time of the Fit and how to be accommodated to the Symptomes ibid. What Diet is to be prescribed for those afflicted with a Feaver 150. FINIS * The Origin is Thalamus Plin Epist 2 lib. 6. Surely this is an Hyperbole i. e. the Dutch
second Opinion is attributed to Baccius and Folius both which sharply maintained that the Chylus passeth from the Intestines to the Liver and Spleen through the Ductus Pancreaticus The contrary of which is as clear as the Meridian Sun Seeing that nothing is received from the Gutts into this Ductus but only the Juyce sent forth by it self to the Intestines The third Opinion is ascribed to Johan Veslingius because in his Systeme of Anatomy chap. 4. he thus speaketh of the Pancreas The use of this Ductus is not obscure for seeing it hath acertain Juyce not much unlike to the Bile it is manifest that such an Excrement is separated from the Chylus by a further Concoction and being conveyed into this Vessel is thence emitted into the Duodenum Asellius Riolanus and others favour this Opinion but Experience contradicts it and manifestly sheweth that the Humour contained in the Pancreas is never really in it self bitter and therefore in no wise to be compared with the Bile If at any time it happens that the Probe being put into this Ductus be yellow every one will easily believe that this is not occasioned by the Humour contained in the Pancreas but from the Bile as well flowing from the Ductus Cysticus as the Hepaticus immediately into the Intestine especially if he consider that the Stylus is spotted by the Bile before it passeth from the Intestine to the Ductus Pancreaticus and again that it passeth through the Bile whilst it is drawn out For the Ductus Pancreaticus and the Ductus Biliarius in Men perforate the Intestine in the same place And although the most famous D. Van. Horne in a Bilious Diarhaea saw that Vessel full of Choler we say it was Preternatural in as much as the Bile which Copiously adhered to the end of the Ductus as is wont to happen in a Diarhaea was thrown into the Cavity thereof by the Agitation of that dead Body Also that the excrement of the further Elaboration or Concoction of the Chylus is not sent into this passage is manifest in regard the same is witnessed by Occular Inspection In some Animals that Glandulous Body doth not at all touch the Milky Vessels and in others it only passeth over and in no wise enters their Substance as also because they are easily separated from the Pancreas without the Effusion of any Chyle as we have formerly demonstrated in Dogs Cats and other Animals Therefore we do not see upon what ground they might maintain the further Concoction of the Chylus to be celebrated in it unless they following the Opinion of Asellius would take this Glandulous body for the Middle Glandule of the Mefentery into which the Venae Lacteae are altogether immersed The fourth Opinion is of Bartholinus as is manifestly apparent from his Anatomy Chap. 13. De Pancreate where he thinks the Bile to be purged Naturally by its Ductus and will have it to be the Bilar-Vesicle or Gall-Bladder of the Spleen so that the same use which the other affords to the Liver he believes that this affords to the Spleen Which Opinion by the leave of so great a man Anatomy in our Judgment seems to confute Seeing the Ductus Pancreaticus passeth not to the Spleen neither are there any other Vessels which do convey any thing from the Spleen to it For there are found only two kinds of Vessels which carry any thing back from the Spleen viz. The Veines and Lymphatick Vessels But the Veines carry back the Blood to the Liver and the Complication of the Lymphaticks carrying from the Spleen do not in like manner go to the Pancreas but to the great Receptacle of the Chyle so that nothing can be discharged out of the Spleen to the Pancreas as our tryal in France hath sufficiently manifested for their sakes who judging this to be the best Opinion of most Authors rejected ours We tyed a Dog upon a Table as is Demonstrated by the first Figure of the third Table and when we had made a little Hole in the left Hypocondrium with our two fore-Fingers we pull'd out the Spleen whose Bloody Vessels we tyed with two or three several Ligatures and afterwards we cut the same in sunder between the Spleen and the Bonds and when we had quite taken away the Spleen we drew together the Lips of the Wound with small threds in three or four several places whereby this Dog in ashort time being well cured was returned to us at which we did not at all wonder because we once had a Bitch which brought forth three or four Puppies after the Extirpation of her Spleen and two Mouths after the loss of the Spleen in the same Dog we collected a notable quantity of the Pancreatick Juice which the Professors of Andegave the Doctors of Vtrecht D. Haverloo and D. de Maets judged to be acidly Salt which being true none as we think free from Prejudice will maintain that the Succus Pancreaticus proceeds from the Spleen Also it is worthy to be noted That those Dogs did no less greedily desire or better digest their Food after the Extirpation of the Spleen than before from whence we receding from the Common Opinion judge that no Fermentitious Matter or Humour is sent from the Spleen to the Stomach The Fifth Opinion is attributed to the most Famous Lindanus seeing that in his Medic-Physiol c. 5. Art 5. pag. 114. he saith When I consider what appertains to the Vse besides the structure of the Pancreas how many Diseases Practise takes notiee of in it I cannot doubt but that the thicker and more useless Purgations of the Blood are thrown out into it by the Ordinary Law of Nature so as they may be corrected by the Spleen and also by an Extraordinary all the Melancholy which either an Intemperate Diet or Disease hath bred The Ductus it self gives us cause to believe That they are both carryed to the Intestines and Curation teacheth the same by the Medicines often required And this Opinion seems also to us to be contrary to the Truth seeing that the Pancreatick Juice as often as it hath been truly collected by us alwayes appeared Limpid like Wine But what we shall say concerning the Excrementitious Humour will sufficiently appear by the following Article and also by those things which shall be spoken of presently after The Sixth Opinion is manifest enough from Wharton's Treatise of the Glandules Chap. XIII whilst he writes Therefore I think that this Glandule as likewise all others do minister to the Nerves and that it receives some of the Superfluities of the Nerves of the Sixth Paire with the little Branches of the Spinal Marrow in the greater folding of the Vnitings and by its own Proper Vessel carries it to the Intestines But seeing that the Nerves are designed to carry Animal Spirits we do not understand upon what ground the industrious Anatomist will hold that the Excrementitious humour is carryed through them and wherefore he will affirm that it is
Seeing than that by Reasons and Experiments already sufficiently inferd it is manifest That the Humours as well of the Conglobated as the Conglomerated Glandules are not Excrementitious We think fit before we proceed any further to propose their Way or Mode of Generation It hath been in times past believed by the Antients to say nothing concerning Faulties and other their Figments that the Glandules did imbile Superfluous Humidities like unto Sponges But to the Neotericks it seemed after a more attentive Examination of their Structure that this Simillitude was greatly wide of the Truth by reason the Glandules are not every where open to the Pores but are sufficiently cloathed on all sides with a strong Membrane therefore they think that nothing entreth into the Glandules unless it be thither propelled by the Arteries and Nerves But the Arteries carry the Humours of every kind to the Glandules under the Colour of Blood every of which by reason of a certain Disposition of the Pores even as Seives do admit such Particles of the Humours which in respect of their Magnitude and Figure have the greatest Analogy with the little Pores in the mean while excluding others which have with them a lesser Simillitude which therefore by the name of Blood are constrained to return to the Heart from whence being more exalted in their passage they are presently driven indiscriminately by the Pulsifick force thereof to the Glandules and other parts of the Body but notwithstanding the Particles fitted to the Generation of the Pancreatick Juice are no where more easily separated than in the Pancreas no where more serous than in the Reins no where more commodiously Bilious than in the Liver so of the rest Because there are some parts of the Body which do more commodiously receive this or that Humour into the Pores than others Nature hath therefore invented a singular Artifice whereby it doth so happily absolve so diverse a work in diverse parts of Animals which they do less admire who diligently consider with themselves that the like thing doth necessarily happen in Plants For we see various Plants posited in the same Sand each to admit a peculiar Juice which nevertheless is so Homo-geneous that it may contain in it self diverse Particles as we see in Trees whereon by the Industry of Gardeners divers Fruits do grow whereas also divers Branches or Twigs are grafted into the same Stock which by reason of the different Constitution of their Pores they admit this and not that part of the Liquor or Sap others being excluded which have a lesser Affinity with their Pores The which things being equally granted we may inferre that the matter fitted to the generation of the Pancreatick Juice is separated from the Blood by a certain disposition of the Pancreas yet not so exactly but that it may bring divers other Particles with it as occular Inspection doth ascertain us to happen in the Reins in which indeed primarily the more Serous Particles of the blood after the manner of Transcolation are separated from its intire Masse yet nevertheless we note those many Saline Bilious and other Humours which are as it were snatcht away therewith by reason of them or those Particles largely abounding in the Body in like manner as Chymistry doth Demonstrate all these things to our Eyes as clear as the Meridian Light The Animal Spirits joyne themselves to the Succus Pancreaticus by a continual Circulation continually separated from the Blood with which being joyn'd together by an Amicable Connexion they run into the Intestinum Duodenum From whence it is Conspicuous that our Pancreatick Juice is not simple but compounded of divers this especially Acid Aqueous Saline and other Particles therein found adjoyned to the Animal Spirits by whose Volatile Sweetnesse the force of Acids is restrained whence it happens that the Pancreatick Juice is Naturally Acidly-Temperate Some may say after what manner may the Pancreatick Juice be Acidly Temperate seeing that in the Precedent Chapter we have said that it is very often Acidly-salt and naturally may be said to be such as alwayes or for the most part it happeneth to be But we shall Answer That perhaps it so happeneth in Dogs onely because they ought to digest Bones and other things of a harder Concoction but in Men we judge there is no such Salsitude existant or required Because in Men that which is Vomited is either Insipid or Bitter or Acid very rarely and perhaps never Acidly Salt the which undoubtedly would happen if their Pancreatick Juice were Naturally such But being granted that in men likewise as in Dogs it may naturally be Acidly Salt Whether then will our Hypothesis run Nowhither Because a Salsitude joyned to it as hereafter shall be declared doth no way impede its primary Operation CHAP. V. The Liquor of the Glandules in the Body it demonstrated to be necessary and that the Pancreatick Juyce doth effervesse with the Bile ALL these things premised deservedly who can ask what the Juyce of the Glandules may perform in the bodies of Animals To whom we shall answer that the juyce of all the Conglobated is subservient to Sanguification but the liquor of the Conglomerated is ordained to other uses For that which is generated in the Maxillary Glandules and other of the Conglomerated placed about the cavity of the mouth for the most part absolveth the Fermentation of Aliments in the Stomach And that liquor which is generated or separated in the Conglomerated Glandules of the Pancreas seems to us to perform far more Seeing that Nature for the most part so wisely disposeth matters that one and the same thing may be accommodated to many But seeing the use thereof is not yet sufficiently known we shall examine what is first effused from it into the thin Intertine and also happeneth in the same There is a sufficiently large quantity of this Pancreatick juice continually brought to the thin Gut we remember there hath been collected from one Dog in the space of seven or eight hours two Drachms half an Ounce and from a Mastive an intire Ounce that it may be continually lifted up and fermented with the Bile flowing from the ducts of the Liver to a double or tripple quantity for as much as we could observe by the benefit of an instrument applied to their passage into the intestine in Doggs being therein carried with a certain strugling motion That this Effervescency is excited from the acidity of the Pancreatick Juice and the concourse of the Bile abounding with a fixed and volatile salt we dare the more freely assert because hitherto we have seen no example of an acid spirit concurring with a lixiviate salt to happen without an effeverscency sufficiently manifest so that all impediments were taken away That both salts are found in the Bile Chymistry that most excellent and famous Medical instrument of truth doth prove by the benefit of which we can separate a volatile salt effervescing with an acid spirit and lixivious
he declares that Aqua Mulsa or Hydromel or if to cleanse more powerfully with the Decoction or bitter Juice before-mentioned of Worm-Wood Centaury or Lupines that may be effected adding Honey or Gall which above all other things as hath been often said doth make those things which are Viscous Fluid c. But the Succus Pancreaticus being pregnant with a Subacid Spirit as appeareth by the Precedent Reasons and Experiments doth in like manner augment the Viscidity of the Aliments by the Solution of their Fluidity the which being so as it is more than sufficiently known we will not delay time by further proofs concerning the Manner wherby Acids in the thin Gut do return to a Liquid and Fluxile Motion or other-wise to an Ineâ—t and Pituitous Viscidity we shall only say that in our Judgement it so happeneth for as much as by the Tenuity and Sharpness of the Parts stirred up by the Effervescency the Phlegme is thereby as with Swords incided and attenuated into very Minute Parts That which attaineth a Whitish Colour then observable in the more Fluid part of the Aliments we think it deducible from the Acidity of the Pancreatick Juice because we may note that many other things abounding with a Lixivious Salt and Oyle do wax White upon the affusion of Acids So that Vinegar or Sharp Wine being poured upon common Sulpher dissolved with any Lixivium and grown Red that Reddish Colour is so changed that it is made almost like to Milk Wherefore also it is called by the Chymists Lac Sulphuris The same is apparent in the Resinious Extracts of Vegitables as also in Spirit of Hart's Horne or Soot being Replete with much Volatile Salt with which an Acid Spirit being mixed acquires a Milky Colour All those things being rightly considered we judge Secondly That the Effervescency in the thin Gut is exceeding necessary for the right Separation of the profitable Parts from the unprofitable But perhaps some who are altogether wedded to Antiquity admitting nothing which to them is Novel because they have read or understood nothing in the Antients concerning this our expected Secretion by Fermentation will not think that such a preparation is required to separate the profitable parts of the Aliment from the unprofitable but that the alteration which is performed in the Stomach is sufficient to this purpose in which if any thing be wanting it may be Consummated by the Peristaltick Motion of the Guts by the help whereof it s more Fluid parts are thrust forward into the Milky Veines the Foeces with the remaining thicker and lesser profitable parts passing away by the Channel of the Intestines To the which we deny not but that something is contributed to this matter both by the said Fermentation and the Peristaltick Motion of the Guts nevertheless we do not think that any Physitian unless a Slave to the Antients amongst all those things which are daily observed in the dissecting of Brute Animals and Medical Practiss or at least-wise may be observed will reject this cause proposed by us If first of all he diligently consider that in the Coeliack Flux the Aliments sometimes viscid like a Pultiss and every where alike and sometimes mixed with a whitish Liquor are purged out But this Diversity of Colour happens by a Contingent or Non-contingent Secretion of profitable parts from the unprofitable by the said Effervescency which who can but in vain Attribute to expression alone Yet we deny not that by the Fermentation of Aliments alone rightly performed in the Ventricle something Fluid may Spontaneously pass away from the rest of the Aliments more Pultatious nevertheless that is but little if it be compared with the large quantity of noble Chyle which is continually strained through the Venae-lacteae or also from thence swimming up in the Caeliack Flux so that then the more watery part of the Chyle freely going forth by the Compression of the Bowels alone is more without Effervescency than the other which is more white or as we may say more Milky In that Spontaneous Separation of the parts wont to happen through Fermentation the Spirituous indeed first go forth with the Watery necessary for the Reparation of the Animal spirits We have an example in the Fermentation of Plants other things abounding with a Volatile Spirit in which the Spirituous Particles alwayes expanded and endeavouring to flee through the Pores of the Stomach and Guts being loosed from their Fetters rush through the Pores From whence we are fully perswaded that after the Assumption of the most Spirituous Aliments a suddain strength is found in men and although it be Inconspicuous to our Bodily Eyes that the Spirits by the same reason are diffused through the Pores of the Body nevertheless after a manner we understand it with the Eyes of our Mind whilst we see a Stupendious Vertue in some Medicaments externally applyed The same thing is often observed by Anatomists when after the Incision of the Peritonaeum they receive the Foetid Flatulencies passing through the Tunicles of the Guts to the Nostrils But because the Spirituous and Volatile parts are not sufficient to sustain Life but Moreover Acid Oleous and Salt parts are also required therefore there is need of a new Alteration of things assumed that those parts by a decent Copiousness might be separated from the Superfluous and Unprofitable Which alteration we call Effervescency and by help of which we judge with our sometimes Famous Professor Francis de le Boe-Sylvius from whose Lectures as well publick as private we do not deny to have drawn many Fundamentals of this Doctrine that Secretion to be accomplished We do not only judge by that Effervescency mediateing the more Subtile and Fluid parts of Aliments but also the Pituity by the help thereof dissolved in the thin Gut part of which is carryed together with the better Portion of the Bile and Succus Pancreaticus through the Vermiculous crust of the Intestines into the Milky Veines from hence to the Cisterne or Common Receptacle of the Chyle and Lympha placed in the Region of the Loynes under the Appendices of the Diaphragma and from thence ascends through the Chyliferus or more rightly the Lymphatick Ductus Thoracicus because it continually carryeth the Lympha and the Chyle only by Intervals to the Subclavian or left Jugular Veine that from thence it may descend with the Blood through the Superiour Trunck of the Vena Cava descending into the right Eare of the Heart and the right Ventricle thereof And in the right Ear and right Ventricle of the Heart it is confused both with the ascending and descending Blood and also impregnated with the Pancreatick Juice the Bile Phlegme and Lympha from whence it acquires a requisite Consistency of Blood This confirms what we have said That any thing acid Coagulates all Fatness and Oyle But because on the other side the aforesaid humours have in themselves a force of attempering we need not fear too great a Consistency of the Blood
Pancreatick Juyce being driven to the Intestines in a lesser quantity will not sufficiently free the Gutts from the superfluous Humidity in them and so will occasion many Obstructions as the Learned R. Lower who judgeth this juyce to be ordained by Nature to cleanse the Chyle he writeth in his Treatise of the Heart Chap. 5. page 215. that by the defect thereof he hath observed Obstructions of the Venae Lacteae in these very words It seems to me most true that that great Glandule namely the Pancreas is seated in that place and that Ductus to be opened into the Intestines that the Lympha for so he calleth the Pancreatick Juyce being there separated may be mixed with the descending Chyle whereby it may more readily enter and more expeditely pass through the narrow Channel of the Lactean Veins and indeed the Chyle in the Milkey Vessels either because of its crascitie or for want of potulent Liquor which ought to be for its Vehicle may sometimes be apt to be stagnant and so concrete and by the same reason to stop and altogether fill up those Vessels as in a Dog whose Pancreas was obdurated I once observed Neither also will it sufficiently promote the Natural and due Separation of the Chyle from the Excrements and that especially if the Aliments be more dry or of a more difficult Fermentation Hence necessarily follows a diminished Nutrition of the whole body as also a universal Languishing so that such may rather be said to draw Life than to live But the Pancreatick Juice being separated in a larger quantity and brought to the Intestines will as it were pare off not only their superfluous Pituity but also that necessary part which should defend them from Injuries like a Curry-Comb and besides it will separate more than it ought from the assumed Aliments so that sometimes the unprofitable and excrementitious parts together with the profitable may be conveyed to the Mass of Blood sometimes only the profitable Parts but in a larger quantity than they should may be carryed by the same wayes From whence if here we say a Pethora will happen and thence a Cacochymy Who can overthrow our Assertions More-over we think that the Lancionations in the left Hypocondria first molested by courses do proceed from too great a quantity of the Bile and Pancreatick Juyce separated from the Blood by a more vehement Motion of the Body and the stirring up a greater Effervescency For it is most certain that Running or any other vehement Exercise of the Body doth accelerate the Motion of the Blood through the whole Body which seeing it is the cause of the Separation of these or other Humours then it is also necessary that those Humours be deposited into the Guts in a greater plenty which being separated in a Natural Quantity and Quality if as we have already proved they may excite a natural and friendly Effervescency to Nature may not the contrary happen when they are otherwise disposed by exciting an Effervescency greater and troublesome to Nature After a wonderful manner doth that place confirm this our Opinion in which those paines are perceived by course and very ordinarily though unjustly are ascribed to the Spleen because the Spleen is not in that place where those pains do in us excite a Molestation but hath its seat more down-wards because in that place those paines do manifest themselves in the Anteriour part of the Hypocondria where the thin Gut M emerging under the Mesentery N doth lye by the Peritonaeum as is to be seen in the first Table where we have Delineated to the Life the Scituation of that Intestine The inequal separation of the Succus Pancreaticus and propulsion thereof to the Intestines produceth various Mutations in the Guts and else-where concerning the suddain Happening of which no man will ever assigne a fit Reason who will not give heed to those things Hence we think to be deduced the suddain Deliquiums of the Wind sometimes advening erratick Feavers intermitious of Pulses c. The Pancreatick Juice being more fluid will more dilute the Pituity of the Guts and perhaps sometimes occasion the Flux of the Belly especially if it be conjoyned with a Salsitude by whose acrimony the Guts are provoked to their Contraction and unless that Flux of the Belly follow the Peristaltick Motion of the Guts it will necessarily express a greater Quantity of Chyle into the Venae Lacteae from whence the same incommodities will arise which we have deduced from the Pancreatick Juyce separated in too large a Quantity The more Viscid Pancreatick Juice concreting by the least external Cold will occasion Obstructions as also intermitting Feavers and likewise astringe the Belly Concerning the sensible Qualities and first of the Rellish there is sometimes produced a Pancreatick juyce less acid from whence there is neither a due Effervescency in the Duodenum and therefore not a necessary Separation of the profitable parts from the unprofitable nor a desired Consistency bestowed on the Blood and therefore they in whom such Blood is have been less able to resist Pestilential Venom than those in whom by the laudable Acidity of their Pancreatick Juice have also a more Laudable and greater Consistency of their Blood Hence the reason is also clear Why Melancholly Men are less afflicted with the Plague than those who are endued with a Bilious blood For we think that no man may be infected with the Plague so long as the Natural consistency of his blood is preserved We assert this the more freely because we see the blood in all persons infected with the Plague to be altered and obtain a far more fluid consistency So that if sometimes by chance Negligence Ignorance or any other urging Cause as for example too great a Plethory spitting of blood bringing a present danger to Life let a Vein be opened the blood flowing out although refrigerated nevertheless is in no wise coagulated neither can it acquire a due consistency even as sometimes is wont to happen to the animal Spirits being loosed from their Fetters and dissipated from the acidity existing in the blood wherefore also such a blood by divers Practitioners is called putrid We commonly say because it may so happen that the whole Mass of blood not as yet equally infected the laudible part of the blood in the cutting of a Vein may only flow out the blood remaining in the body being depraved the which thing Practitioners daily observe to happen in Venae-Section we do not only think with other Practitioners that the blood remains fluid without the bodies of those who are infected with the Plague but do also affirm the like fluidity in the bodies of those extinguished by the Pest as we have learned by Experience which perhaps may seem strange to those who know not the Nature of volatile Salts but not so to us who have very often mingled it with the blood and the blood always remained fluid the which cannot be certainly expected from the commixture
they call Stuypiens doth proceed from the said more Acid Pancreatick Juyce who hath accurately attended to those Invasions and the Symptomes accompanying them and the way of Cure For besides that Acidity which doth very often breath through the Mouth they suffer the Gripings of the Belly the Milk may likewise be perceived to be concreted both upwards and downwards the Excrements of the belly are more Green and give forth a sharp Odour they are also cured by the tempering of Acidity as for Example with Aqua Feniculi Aqua Lilliorū Conuallium Spir. Salis Armoniaci c. The same more Acid Pancratick Juyce carryed to the blood through the Lactean Veines will give it a greater Consistency whence the Blood less Rarifying will produce a lesser Pulse From which Vice highly exceeding we judge a Syncope sometimes to be produced which is not a little confirmed by that Example which Lazarus Riverius relates in Lib. VIII Fol. 358. of his Practice concerning that Syncope which P. Salius as he reports Lib. De Afect Practic Cap. IV. observed in a Girle of 14 Years of Age Who after a dayes suffering of Heaviness of the Head Vertigo and grievous Anxieties the day following suddainly dyed Afterwards her Body being diffected the whole blood in the great Artery and the Vena Cava appeared to be Concreted and so changed that it might intirely be drawn out from the Vein and Artery even as a Sword out of its Scabbard Concerning which thing if any doubt either by ours or others Examples let him take an acid Liquor and pour it by degrees into the Vein of any Living Dog and he shall not only observe the Blood therein to be so Coagulated and Concreted that the greater bloody Vessels may be transversly cut without the Effusion of the blood but also when the acid Liquor shall come in a notable Quantity to the right Ventricle of the Heart that it will presently extinguish and kill the Dog Also no man will deny that Convulsions for the most part proceed from an Internal Cause from the Acrimony of Humours irritating the Nerves and causing by a greater Influx of the animal Spirits into the Muscles Involuntary and also Violent Motions But when there is a two fold Acrimony of Humours viz. Acid and Salt some perhaps may doubt which of these do most frequently produce those Convulsive Motions But for as much as we can observe they rather proceed from an acid Acrimony than a Salt because we see that Aromatick Medicaments and those abounding with a Volatile Salt do very much conduce to their Cure which would never come to pass if they drew their Original from a Saline Acrimony Besides they are accompanyed with such Symptomes which are wont to be the Concomitants of Diseases arising from an acid Acrimony Yea the Effects of Acids are allowed to be far more powerful as is to be seen in Helmont De Lithiasi Cap. 9. Pag. 725. § 71. where he relates that he saw a Chymist which after he had been much Conversant about making of Aqua Regia he fell into the Palpitation of the Heart Convulsions and many other Incredible Dolours by reason of the acid Exhalations which mingled themselves with his Blood From the same Acidity we stedfastly believe That the Strangury is very often produced seeing that together with other Students we have sometimes found the Urines of such as have laboured under the Strangury in the Hospital of Leyden to be Acid and also seen the same Persons cured with such Medicines as temper Acidity The which if you are minded to try saith Helmont De Pleura Furente § 14. Whether or no the Strangury may not proceed from Acidity mix some Drops at least of sharp Wine with the Vrine lately sent forth without pain and inject it again by a Syringe and you shall find to your Pain that what I say is true Also that from the more acid Pancreatick Juyce Ulcers do sometimes break forth in the Skin corroding the same as also producing very great paines they will not deny who following the Opinions of the Antients determine them to arise from the Atra-Bilis seeing that the Atra-Bilis of the Antients as we have above Demonstrated hath its Original from the more acid Pancreatick Juyce We are like-wise plainly perswaded that the more acid Pancreatick Juyce especially if it hath any Austerity conjoyned with it produceth a greater astringency of the Belly For if the Bile by its Acrimony irritating the Guts as is granted may excite the Flux of the Belly why may not that which is contrary to such a Bile produce a contrary Effect Notwithstanding if the belly be bound by a Viscid Matter then we think likewise that a Flux may happen from the sharper Pancreatick Juyce as it hath a power of inciding and attenuating the Viscid Pituity From which it is manifest that the Pancreatick Juyce according to the Diversity of Humours concurring with it doth very often produce a diverse and contrary Effect which thing we would have well noted lest we should seem to contradict our self in explicating the Effects of this juyce As yet we think even as we seem to have already said that the Atra and Eruginous Bile is excited from the more acid Pancreatick Juyce and a certain sharp Bile concurring and consequently all Diseases which Authors deduce from them and therefore they are not cured by other Medicaments than those which are fit to correct the more acid Pancreatick Juyce Which as it is Consonant with Reason so it will not appear Incredible to those who will consider the things above spoken by us with a more attentive Mind But perhaps some will say after what manner doth the Pancreatick Juyce produce the Atra-Bilis seeing that we have ascribed the Whitishness of the Chyle after the Effervescency in the thin Gut to the acidity of the Pancreatick Juyce To which we answer That Acids according to the Diversity of the matter where-with they are mixed do also produce a divers Colour for example pour an acid Spirit to common Sulphur dissolved in a Lixivium and its red Colour will be changed into white Antimony Calcind with Nitre or Chalk being boyl'd in Fountain-Water and any acid thing being affused to its clear Colature will presently acquire a Saffron Colour A clear Infusion of Galls mixed with the Solution of Vitriol maketh Ink to which if you add the acid Spirit of Vitriol that Ink will lose all its blackness and become clear like to Fountain-Water The Blew Tincture of Violets being mixed with Oyle of Vitriol will wax into a Purple The Wood Acanthus brought from Brasile being infused in Common Water doth freely yeild a red Tincture which put to Distilled Vinegar acquires a Colour like to White-Wine A Knife after it hath cut a Pomecitron in the Middle unless it be wiped and cleansed from the Soure Juyce of the Citron in a short time will be reduced to a nigrous Colour And why from the same acidity too much exalted
with a sence of Cold and terminated with heat For the Pancreatick Juice being made more sharp by stagnation in one or more of the lateral Ducts after which flowing into the thin Gut there exciteth such an effervescency with the Bile wherein the Succus Pancreaticus by its predominant Acidity every way emits or sends forth acid Exhalations affected with a sense of Cold which when they touch the Gall-bladder by their acrimony provoke it to its Contraction from whence the Bile breaking forth into the Intestine in a more than usual quantity overwhelmes the Pancreatick Juice and raiseth therewith such an Effervescency in which the Bile predominating Excites heat by sending every way its exhalations or Emissaries This our Opinion is in a wonderful manner confirmed by the Vomitings which very often happen to the Sick at one time so cold and Acid that bringeth a stupor to the Teeth and again on the contrary another while so hot and bitter that they believe they Vomit nothing but pure Choler But some perhaps may ask why we deduce Vomitings and acid belchings rather from the Pancreas than from the Stomach We answer because it is agreeable to experience that the Pancreatick Juice is Acid and seeing that the searchers of Nature do as yet dispute concerning the ferment of the Stomach and its Generation we judged that it ought to be determined rather from a certain than an uncertain Cause And if it shall be evinced by further search in the stomach of Men we speak not of Birds who require a stronger fermentation to digest Stones and other things of a hard consistency for the Generation of Shells that any other ferment is generated besides the Spittle continually swallowed and that to be Acid then shall we be so much the better able to prove an Effervescency to be excited in the thin Gut between the Bile and the Pancreatick Juice Seeing that the Temperate or Natural Acidity of the Pancreatick Juyce would be helped by the acid Ferment of the Stomach and from thence the Effervescency would be the more powerfully performed It is further proved that the Acidity cast forth by Vomitting doth not proceed from the Stomach but from the Intestines by Vomitories exhibited out of the time of the Fit by the help whereof first an insipid Matter afterwards by further straining an Acid and Bilious Matter is vomitted up the contrary of which would happen if the Soure and Cholerick Matter did proceed from the Stomach Concerning the manner by which Acids may get to the Stomach no man of a sound mind will doubt who determines the Bile ejected by Vomiting to proceed from the Intestines Seeing that the Pancreatick Juyce may and ought to be driven through the same wayes as the Bile flowing to the Intestines by their inverted Peristaltick Motion with the same ease to the Ventricle as we have above demonstrated Neither doth the place a little confirm this our Opinion in which a Feaverish fit beginning is for the most part perceived Cold then Hot as also a most fierce pain We understand the Region of the Loynes in which the first part of the thin Gut lies under the Mesentery as is to be seen Tab. I wherein the Confsux and Effervescency of the Bile and the Pancreatick Juyce is Celebrated from which the Particles of those Humours being agitated upon the Ligaments of the Mesentery and other Nervous and Membranous parts they dash against them with an Impetuous force So that that Effervescency may sometimes be perceived by the Touch in the Sick as we have above demonstrated Nor does the Pancreatick Juyce being made sharp by stagnation only exercise a tyranny in the Region of the Loynes but also sends forth its acid Exhalations both upwards and downwards Who doubteth that from the one the Torments of the Belly and from the other Acid belchings do proceed But if those Exhalations penetrate through the Venae Lacteae to the Heart by Incrassating the Blood gives an occasion of a lesser Pulse which nevertheless by its corroding Acrimony produceth one more frequent The Acid Exhalations being subdued in manner afore-said Salt and Bilious Exhalations do follow which again by attenuating the Blood do no less excite a great and sometimes also a more frequent Pulse by irritating the Heart and that so long till their Acrimony being spent they can no longer irritate or provoke the Heart Which done the Vigour and Natural pulse of the Heart is returned So that very often the most skilful can hardly judge whether they have a Feaver or no. We will not here speak lest this Chapter should swell too much with that which we purposed to finish in few Words concerning six Hundred other Symptomes which are wont to accompany Intermitting Feavers seeing we are perswaded there are none at least of those who with an attent mind have considered that the Juyce or its Emissaries after a diverse manner disposed doth perambulate the whole Body and may produce diverse Symptomes but may from these things deduce them by their own proper Industry Which seeing it is so we leaving those small Circumstances shall rightly pass on to the Cure of intermitting Feavers which as it Primarily consisteth in taking away Obstructions and correcting the Pancreatick Juice and other Humours if they be Vitious so it may be most succesfully performed first by Medicines inciding and attenuating tough Phlegme and sometimes expelling it from the Body Secondly By adhibiting Remedies which are indued with a force of correcting and temperating the Pancreatick Juice offending by its Acrimony Thirdly By correcting other Humours in the Body this or that way so peccant that they may Cherish the Vicious Effervescency excited in the thin Gut between the Bile and the Pancreatick Juice For the taking away the Obstruction temperating the more acid Pancreatick Juyce and the diminishing the Cold from thence proceeding these following Medicines do much conduce viz. Water of Parsly Fennel Baume Simple Treacle-Water Salt of Worm-wood of Centary the lesser Syrup of Carduus Benedicttus or the five opening Roots and the like being mixed according to Art especially if taken halfe an hour before the feaverish Cold invades the Sick who ought to be kept in his bed or other warm place that Sweat may be a little promoted or at leastwise that the operation of the Medicine may not be hindered We say half an hour before the feaverish Cold invade the Sick because Reason teacheth and Experience proveth that cutting and attenuating as unobstructing Medicaments do then with a far more happy Success absolve that for which they are Administred than if they were exhibited at any other time the Reason of which seemes to us because those Medicines begin to operate at that time wherein the Pancreatick Juice by its Acrimony doth molifie the Obstruction and so by a united force may more strongly and more happily dissolve the Obstruction than if either of those only were opperating Moreover It very much diminisheth the Feaverish Cold which as yet