a_o pain_n and_o swell_v of_o their_o belly_n a_o rumble_a in_o their_o side_n under_o the_o rib_n they_o have_v a_o weak_a pulse_n a_o tremble_a at_o the_o heart_n a_o pain_n in_o the_o head_n a_o redness_n in_o their_o lip_n face_n and_o eye_n which_o be_v sometime_o distort_v sometime_o so_o fast_o shut_v that_o they_o can_v hardly_o be_v open_v and_o be_v now_o high_a in_o the_o fit_a they_o be_v ready_a to_o be_v strangle_v be_v deprive_v of_o voice_n sense_n and_o motion_n except_o such_o as_o be_v convulsive_a some_o cry_n out_o with_o a_o despair_a voice_n and_o present_o fall_v down_o for_o dead_a their_o pulse_n be_v then_o very_a weak_a and_o sometime_o none_o to_o be_v feel_v when_o the_o fit_a be_v go_v off_o their_o cheek_n redden_a they_o recover_v their_o sense_n their_o eye_n with_o a_o very_a dull_a and_o heavy_a aspect_n be_v open_v and_o at_o length_n fetch_v deep_a sigh_n and_o sometime_o pour_v forth_o shower_n of_o tear_n they_o come_v to_o themselves_o this_o be_v the_o picture_n of_o that_o dismal_a disease_n which_o most_o frequent_o afflict_v poor_a miserable_a woman_n though_o man_n be_v not_o exempt_v from_o it_o in_o some_o all_o or_o most_o of_o these_o symptom_n meet_v in_o other_o only_o the_o strangle_a or_o danger_n of_o be_v choke_v with_o some_o other_o accident_n be_v observable_a but_o general_o the_o fit_n be_v so_o terrible_a and_o amaze_a to_o they_o who_o consider_v not_o the_o reason_n of_o these_o affection_n that_o by_o the_o vulgar_a the_o person_n subject_a to_o they_o be_v believe_v to_o be_v bewitch_v or_o possess_v by_o the_o devil_n the_o ancient_a physician_n do_v with_o one_o consent_n deliver_v that_o seed_n and_o menstruous_a blood_n corrupt_v in_o the_o womb_n and_o genital_a part_n do_v send_v forth_o malignant_a vapour_n which_o with_o violence_n carry_v up_o the_o womb_n against_o the_o diaphragm_n and_o organ_n of_o 〈◊〉_d spiration_n and_o thereby_o sudden_o stop_v the_o motion_n of_o the_o heart_n and_o lung_n and_o from_o this_o impetuous_a motion_n of_o the_o womb_n they_o suppose_v to_o be_v cause_v that_o sense_n of_o a_o globe_n rise_v upward_o in_o the_o belly_n but_o they_o who_o have_v so_o much_o insight_n in_o anatomy_n as_o to_o know_v that_o the_o womb_n be_v immovable_o fix_v to_o its_o place_n by_o ligament_n and_o that_o in_o virgin_n it_o be_v usual_o not_o much_o big_a than_o a_o walnut_n and_o do_v consider_v that_o in_o woman_n with_o child_n the_o womb_n press_v upon_o the_o very_a stomach_n and_o yet_o never_o cause_v these_o accident_n and_o that_o oftentimes_o in_o dropsy_n of_o the_o womb_n that_o part_n be_v extend_v to_o a_o vast_a bigness_n and_o be_v full_a of_o putrid_a humour_n and_o yet_o none_o of_o these_o suffocation_n or_o other_o accident_n be_v cause_v they_o i_o say_v who_o consider_v this_o can_v allow_v that_o these_o stupendous_a symptom_n can_v be_v produce_v by_o that_o cause_n the_o learned_a doctor_n highmore_n in_o his_o exercitation_n upon_o the_o hysterical_a passion_n have_v examine_v all_o the_o hypothesis_n invent_v either_o by_o the_o ancient_a or_o modern_a physician_n hystericâ_fw-la highm_o de_fw-fr passion_n &_o hystericâ_fw-la to_o solve_v the_o phaenomena_n of_o this_o distemper_n and_o find_v they_o all_o very_a insufficient_a to_o give_v a_o satisfactory_a account_n deliver_v most_o ingenuous_o his_o own_o opinion_n and_o suppose_v all_o the_o symptom_n to_o be_v cause_v by_o a_o overstuff_n of_o the_o ventricles_n of_o the_o heart_n and_o vessel_n of_o the_o lung_n with_o thin_a servous_a and_o ferment_a blood_n which_o do_v so_o distend_v and_o fill_v they_o that_o the_o lung_n be_v thereby_o render_v unfit_a to_o comply_v with_o the_o motion_n of_o the_o diaphragm_n and_o chest_n and_o the_o heart_n disable_v to_o discharge_v its_o self_n by_o its_o pulse_n of_o the_o burden_n which_o oppress_v it_o though_o it_o attempt_v to_o rescue_v its_o self_n by_o more_o frequent_a pulsation_n and_o from_o hence_o necessary_o to_o follow_v first_o a_o difficulty_n of_o breathe_v and_o then_o a_o suffocation_n which_o that_o nature_n may_v avoid_v she_o call_v to_o her_o succour_n the_o animal_n faculty_n which_o lest_o she_o perish_v together_o with_o the_o vital_a pour_v forth_o the_o whole_a force_n and_o strength_n of_o her_o spirit_n though_o in_o so_o much_o disorder_n that_o by_o their_o confuse_a sally_n those_o irregular_a motion_n be_v cause_v in_o the_o body_n which_o man_n call_v convulsive_a this_o be_v the_o account_n according_a to_o my_o best_a apprehension_n of_o his_o meaning_n of_o the_o descriptive_a definition_n which_o that_o excellent_a person_n give_v of_o this_o disease_n and_o i_o be_o so_o much_o of_o his_o opinion_n as_o to_o believe_v that_o very_o often_o a_o dyscrasie_n or_o distemper_n of_o the_o blood_n and_o probable_o of_o the_o serum_fw-la or_o whey_n of_o it_o be_v one_o cause_n of_o this_o distemper_n but_o i_o beg_v his_o pardon_n if_o i_o be_o apt_a to_o believe_v that_o even_o then_o when_o these_o fit_n be_v cause_v from_o a_o serous_a dyscrasie_n in_o the_o blood_n they_o be_v rather_o to_o be_v attribute_v to_o the_o impurity_n and_o sharp_a salt_n which_o be_v either_o cast_v off_o upon_o the_o brain_n and_o from_o thence_o distribute_v through_o the_o nerve_n into_o remote_a part_n of_o the_o body_n or_o else_o upon_o some_o of_o the_o bowel_n where_o those_o pungent_a juice_n prick_v and_o vellicate_v the_o extremity_n of_o the_o nerve_n cause_v the_o original_n and_o whole_a system_fw-la to_o participate_v of_o their_o disorder_n than_o to_o the_o blood_n stuff_v and_o distend_v the_o vessel_n of_o the_o lung_n and_o heart_n for_o beside_o that_o there_o be_v many_o woman_n cachectical_a and_o hydropical_a who_o vessel_n be_v fill_v with_o little_a else_o but_o waterish_a blood_n and_o whey_n who_o be_v notwithstanding_o very_o free_a from_o fit_n of_o the_o mother_n it_o be_v often_o observe_v that_o woman_n of_o a_o ruddy_a complexion_n who_o have_v a_o brisk_a and_o lively_a heat_n in_o their_o blood_n and_o that_o rich_a with_o spirit_n which_o purge_v its_o self_n every_o month_n in_o its_o constant_a period_n be_v oft-ten_a miserable_o afflict_v with_o hysterical_a paroxysm_n for_o they_o be_v not_o seldom_o such_o as_o have_v a_o excellent_a good_a appetite_n and_o digest_v their_o meat_n well_o who_o lung_n be_v not_o flabby_a weak_a or_o dispose_v to_o a_o consumption_n and_o who_o blood_n when_o it_o be_v let_v out_o of_o their_o vein_n and_o settle_v be_v observe_v to_o be_v thick_a and_o full_a of_o fiber_n all_o which_o be_v qualification_n quite_o contrary_a to_o those_o which_o be_v require_v by_o dr._n highmore_n hypothesis_n if_o i_o mistake_v he_o not_o to_o render_v a_o person_n liable_a to_o hysterical_a passion_n moreover_o in_o my_o opinion_n crude_a and_o waterish_a blood_n be_v altogether_o unfit_a to_o be_v set_v so_o impetuous_o on_o fire_n as_o to_o cause_v so_o extravagant_a a_o fermentation_n in_o the_o ventricles_n of_o the_o heart_n that_o by_o overstretch_v the_o lung_n they_o shall_v be_v unable_a to_o disburden_v themselves_o of_o the_o blood_n for_o we_o find_v that_o cachectical_a and_o hydropical_a person_n and_o maid_n in_o the_o green-sickness_n be_v trouble_v with_o a_o shortness_n of_o breath_n upon_o exercise_n and_o walk_v up_o steep_a place_n or_o stair_n which_o undoubted_o be_v cause_v for_o that_o the_o blood_n of_o such_o person_n be_v thin_a and_o waterish_a and_o want_v its_o due_a proportion_n of_o the_o sulphureous_a and_o inflammable_a part_n do_v not_o afford_v a_o sufficient_a quantity_n of_o vital_a oil_n to_o the_o lamp_n of_o the_o heart_n and_o therefore_o when_o upon_o exercise_n and_o motion_n there_o be_v a_o great_a quantity_n of_o blood_n than_o ordinary_o send_v into_o the_o heart_n that_o be_v not_o well_o rarify_v and_o fire_v in_o the_o right_a ventricle_n pass_v not_o so_o swift_o through_o the_o lung_n to_o theleft_a as_o it_o ought_v to_o make_v room_n for_o that_o which_o be_v to_o succeed_v so_o that_o at_o the_o same_o time_n the_o lung_n and_o heart_n be_v overburden_v upon_o which_o a_o difficulty_n of_o breathe_v &_o a_o beat_n and_o throb_v at_o the_o heart_n must_v necessary_o ensue_v beside_o in_o fever_n where_o the_o blood_n be_v most_o of_o all_o rarefy_v and_o ferment_v except_o the_o matter_n of_o the_o disease_n be_v cast_v upon_o the_o brain_n hysterical_a symptom_n do_v not_o constant_o happen_v and_o yet_o the_o sulphurous_a part_n of_o the_o blood_n fire_v be_v much_o more_o apt_a to_o fill_v and_o distend_v the_o chamber_n of_o the_o heart_n and_o vessel_n of_o the_o lung_n than_o the_o whey_n it_o be_v far_a observable_a that_o woman_n who_o have_v their_o course_n too_o frequent_o and_o vent_v by_o the_o womb_n overgreat_a quantity_n of_o blood_n be_v often_o trouble_v with_o
another_o the_o same_o may_v be_v say_v of_o alter_a medicine_n for_o example_n to_o instance_n in_o hepaticks_n as_o cichory_n gentian_n wormwood_n century_n steel_n agrimony_n and_o the_o like_a which_o be_v with_o admirable_a success_n use_v in_o cachexy_n dropsy_n and_o other_o disease_n cause_v from_o imperfect_a sanguification_n though_o it_o be_v now_o agree_v upon_o by_o general_a consent_n upon_o the_o dissection_n of_o hydropical_a person_n that_o part_n be_v often_o find_v little_o concern_v that_o the_o liver_n have_v primary_o little_a or_o nothing_o to_o do_v in_o those_o distemper_n and_o be_v only_o secondary_o affect_v as_o be_v as_o i_o have_v show_v very_o just_o exclude_v from_o the_o office_n of_o sanguification_n and_o yet_o we_o see_v that_o hepaticks_n be_v still_o use_v in_o the_o same_o distemper_n by_o the_o best_a both_o chemist_n and_o galenist_n though_o the_o ancient_a hypothesis_n be_v fling_v out_o of_o door_n as_o for_o m._n n_n deny_v the_o spleen_n to_o be_v the_o receptacle_n of_o melancholy_a and_o assign_v it_o this_o use_n that_o it_o be_v a_o elaborator_fw-la of_o the_o noble_a juice_n viz._n the_o arterial_a blood_n by_o reason_n of_o that_o grand_a intertexture_n of_o artery_n by_o which_o it_o hold_v a_o near_a communication_n with_o the_o vital_a part_n of_o the_o body_n for_o which_o he_o quote_v bartholinus_n walaeus_n and_o highmore_n i_o dare_v assure_v he_o he_o do_v those_o worthy_a author_n great_a injury_n and_o that_o neither_o in_o they_o nor_o any_o good_a author_n who_o understand_v the_o circulation_n of_o the_o blood_n he_o ever_o meet_v with_o any_o such_o opinion_n that_o the_o spleen_n by_o the_o artery_n can_v hold_v a_o near_a communication_n with_o the_o vital_a part_n of_o the_o body_n neither_o do_v those_o author_n which_o he_o quote_v deny_v the_o spleen_n to_o be_v the_o receptacle_n of_o melancholy_n and_o i_o will_v very_o fain_o learn_v of_o this_o excellent_a anatomist_n how_o the_o arterial_a blood_n in_o the_o spleen_n shall_v hold_v a_o near_a communication_n with_o the_o vital_a part_n of_o the_o body_n by_o the_o artery_n since_o it_o be_v evident_a that_o the_o blood_n be_v bring_v thither_o by_o the_o splenick_n branch_n of_o the_o caeliac_n artery_n and_o convey_v thence_o to_o the_o vital_a part_n not_o by_o the_o artery_n but_o vein_n as_o for_o the_o opinion_n of_o walaeus_n and_o bartholinus_n 16._o barthol_n anat._n c._n 16._o he_o have_v gross_o scandalize_v they_o both_o for_o bartholinus_n in_o the_o 16_o chapter_n of_o his_o anatomy_n number_v up_o all_o the_o opinion_n which_o he_o meet_v with_o concern_v the_o use_n of_o the_o spleen_n say_v thus_o ultima_fw-la sententia_fw-la eaque_fw-la verissima_fw-la est_fw-la joh._n walaei_n putat_fw-la autem_fw-la verosimile_n sanguinem_fw-la ulterius_fw-la perficiendum_fw-la a_o cordis_fw-la calore_fw-la dissolvi_fw-la &_o ubi_fw-la be_v a_o cord_n adigeretur_fw-la per_fw-la arterias_fw-la caeliacas_fw-la in_o lienem_fw-la non_fw-la totam_fw-la illam_fw-la massam_fw-la retineri_fw-la a_o liene_n say_v ut_fw-la vesica_fw-la fellis_fw-la tantum_fw-la bilem_fw-la ita_fw-la lienem_fw-la partem_fw-la sanguinis_fw-la acidam_fw-la capere_fw-la quam_fw-la possis_fw-la melancholiam_fw-la appellare_fw-la non_fw-la aliter_fw-la ac_fw-la distillatione_fw-la chymica_fw-la segregari_fw-la a_o rebus_fw-la spiritum_fw-la acidum_fw-la videmus_fw-la illu_z acidum_fw-la humorem_fw-la perfici_fw-la a_o liene_n a_o quo_fw-la lie_v nigrican_n &_o acidus_fw-la sentitur_fw-la hunc_fw-la acidum_fw-la humorem_fw-la permisceri_fw-la postea_fw-la sanguini_fw-la in_o vasis_fw-la &_o chylo_fw-la in_o ventriculo_fw-la &_o eos_fw-la reddere_fw-la tenuiores_fw-la quare_fw-la obstructo_fw-la liene_n crassos_fw-la in_o corpore_fw-la humores_fw-la coacervari_fw-la non_fw-la quod_fw-la crassi_fw-la humores_fw-la a_o liene_n non_fw-fr trahantur_fw-la quos_fw-la nec_fw-la in_o eo_fw-la naturaliter_fw-la licet_fw-la invenire_fw-la sed_fw-la quod_fw-la lien_n attenuantem_fw-la illum_fw-la acidum_fw-la nequeat_fw-la sanguini_fw-la chylo_fw-la recommunicare_fw-la nor_o have_v this_o man_n of_o confidence_n with_o less_o disingenuity_n or_o ignorance_n fasten_v his_o absurd_a fancy_n upon_o the_o learned_a dr._n highmore_n who_o opinion_n i_o will_v deliver_v in_o his_o own_o word_n as_o it_o be_v to_o be_v meet_v with_o in_o his_o anatomical_a disquisition_n of_o the_o body_n of_o man_n illorum_fw-la part_n agam_fw-la 3._o highm_o anat._n l._n 1._o p._n 3._o c._n 3._o qui_fw-la splenem_fw-la cum_fw-la galeno_fw-it succum_fw-la melancholicum_fw-la attrahere_fw-la eumque_fw-la a_o sanguine_fw-la separare_fw-la autumant_fw-la and_o he_o go_v on_o a_o little_a far_o arteriae_fw-la splenicae_fw-la a_o caeliaca_fw-la ortae_fw-la sanguinis_fw-la partem_fw-la melancholicam_fw-la postquam_fw-la ultimam_fw-la in_o cord_n concoctionem_fw-la subivit_fw-la ad_fw-la lienem_fw-la deferunt_fw-la ac_fw-la in_o substantiam_fw-la ejus_fw-la infundunt_fw-la sicuti_fw-la emulgentes_fw-la serosum_fw-la in_o renes_fw-la ducunt_fw-la quam_fw-la lie_v fermentat_fw-la ac_fw-la separate_a these_o be_v the_o opinion_n of_o bartholinus_n and_o highmore_n as_o i_o have_v faithful_o quote_v in_o their_o own_o word_n who_o sense_n either_o he_o understand_v not_o or_o fraudulent_o pervert_v a_o digression_n concern_v the_o use_n of_o the_o spleen_n and_o hypochondriacal_a distemper_n for_o the_o better_a understanding_n of_o the_o use_n and_o office_n of_o the_o spleen_n it_o be_v requisite_a to_o examine_v the_o shape_n make_v and_o mechanical_a contrivance_n of_o it_o that_o as_o by_o take_v a_o watch_n asunder_o we_o be_v inform_v for_o what_o end_n and_o purpose_n every_o spring_n pin_n and_o wheel_n be_v make_v we_o may_v the_o more_o certain_o discover_v what_o the_o design_n of_o nature_n be_v in_o frame_v that_o bowel_v by_o trace_v the_o artery_n vein_n and_o nerve_n which_o constitute_v it_o and_o consider_v the_o quantity_n colour_n site_n figure_n and_o other_o appearance_n which_o offer_v themselves_o to_o our_o view_n and_o first_o as_o to_o the_o bigness_n of_o it_o that_o be_v very_o different_a according_a to_o the_o variety_n of_o man_n body_n they_o general_o who_o have_v large_a vein_n have_v likewise_o great_a spleen_n the_o lesser_a except_o it_o be_v much_o too_o small_a be_v far_o better_a than_o the_o big_a the_o figure_n of_o it_o be_v most_o common_o oblong_v the_o colour_n in_o embrios_fw-la and_o young_a child_n red_a in_o those_o who_o be_v more_o mature_a and_o adult_a inclinable_a to_o a_o blackness_n the_o substance_n of_o it_o consist_v of_o black_a gross_a blood_n congeal_v among_o the_o fiber_n it_o be_v furnish_v with_o three_o sort_n of_o vessel_n first_o it_o receive_v a_o large_a branch_n from_o the_o caeliac_n artery_n which_o disperse_v its_o self_n into_o innumerable_a small_a twig_n among_o the_o fiber_n in_o the_o second_o place_n it_o have_v a_o vein_n with_o sprout_n into_o it_o from_o the_o perta_n which_o be_v all_o spend_v and_o lose_v in_o the_o substance_n of_o it_o except_o only_o two_o arm_n the_o vas_fw-la breve_fw-la which_o go_v away_o to_o the_o stomach_n and_o the_o other_o the_o haemorrhoidal_a vein_n which_o run_v away_o to_o the_o anus_fw-la the_o coat_n of_o the_o vein_n which_o enter_v the_o spleen_n as_o be_v first_o observe_v as_o i_o take_v it_o by_o the_o learend_a dr._n glisson_n in_o the_o spleen_n of_o a_o ox_n the_o far_a it_o go_v grow_v thin_a and_o thin_a till_o at_o length_n it_o vanish_v and_o nothing_o of_o it_o appear_v and_o all_o the_o way_n it_o run_v it_o be_v as_o it_o be_v bore_v full_a of_o some_o lesser_a some_o large_a hole_n which_o receive_v into_o they_o the_o blood_n return_v out_o of_o the_o parenchyma_n and_o these_o hole_n after_o the_o manner_n of_o vein_n branch_n themselves_o into_o the_o parenchyma_n in_o the_o vein_n there_o be_v evident_o to_o be_v see_v valve_n which_o stop_v and_o hinder_v all_o passage_n and_o commerce_n from_o the_o porta_n by_o the_o splenick_n branch_n to_o the_o spleen_n only_o there_o may_v be_v plain_o observe_v a_o anastomosis_n between_o the_o upper_a branch_n of_o the_o vein_n and_o artery_n in_o the_o three_o place_n the_o spleen_n be_v furnish_v with_o nerve_n from_o the_o six_o pare_n according_a to_o the_o ancient_n or_o eighth_n according_a to_o dr._n willis_n which_o with_o their_o numerous_a thread_n and_o fiber_n weave_v themselves_o into_o a_o kind_n of_o net_n upon_o which_o the_o parenchyma_n stick_v leave_v everywhere_o multitude_n of_o little_a hole_n which_o be_v not_o unfit_o resemble_v by_o those_o in_o a_o sponge_n or_o pumy-stone_n into_o which_o the_o small_a artery_n run_v every_o where_o disperse_v among_o the_o thread_n of_o the_o nerve_n empty_v themselves_o of_o the_o blood_n which_o have_v pass_v through_o and_o wash_v the_o whole_a substance_n of_o the_o spleen_n be_v again_o drink_v up_o and_o carry_v away_o by_o the_o vein_n from_o this_o description_n of_o the_o spleen_n it_o seem_v most_o probable_a that_o all_o this_o art_n and_o workmanship_n be_v bestow_v upon_o it_o by_o nature_n that_o she_o may_v make_v it_o a_o part_n of_o some_o eminent_a and_o necessary_a
far_o great_a quantity_n of_o fix_a salt_n than_o the_o body_n and_o we_o see_v that_o in_o dropsy_n chachexy_n obstruction_n and_o the_o like_a disease_n which_o will_v not_o yield_v to_o vulgar_a medicine_n the_o learn_a practitioner_n betake_v themselves_o to_o medicine_n of_o tartar_n steel_n and_o vitriol_n as_o a_o certain_a refuge_n in_o the_o great_a extremity_n and_o it_o can_v be_v imagine_v how_o these_o medicine_n shall_v perform_v such_o certain_a and_o admirable_a effect_n but_o that_o by_o ferment_v the_o blood_n with_o their_o saline_n particle_n they_o supply_v the_o defect_n of_o the_o natural_a ferment_n for_o as_o long_o as_o this_o be_v vigorous_a and_o the_o passage_n be_v open_a from_o the_o spleen_n into_o the_o mass_n of_o blood_n the_o splenick_n leven_fw-mi by_o continual_o maintain_v a_o intestine_a motion_n of_o the_o small_a particle_n of_o the_o blood_n preserve_v that_o liquor_n in_o its_o due_a mixture_n and_o consistence_n so_o that_o the_o grosser_n and_o fine_a particle_n be_v exact_o mingle_v one_o with_o another_o and_o the_o spirit_n free_a and_o at_o liberty_n the_o blood_n be_v render_v fit_a to_o circulate_v through_o the_o most_o straight_o and_o narrow_a passage_n and_o not_o apt_a to_o curdle_n and_o stagnate_n in_o the_o vessel_n and_o by_o this_o mean_n crudity_n be_v concoct_v obstruction_n open_v tough_a and_o slimy_a humour_n attenuate_v and_o the_o blood_n defecate_v of_o all_o its_o excrement_n and_o impurity_n by_o the_o vent_v and_o emunctory_n of_o the_o body_n by_o this_o mean_n not_o only_o the_o juice_n which_o run_v in_o the_o vein_n and_o artery_n be_v rich_a pure_a and_o spirituous_a but_o likewise_o from_o these_o a_o soft_a subtle_a and_o well_o rectify_v spirit_n and_o liquor_n be_v communicate_v to_o the_o brain_n and_o distribute_v into_o the_o nerve_n for_o the_o use_n of_o the_o animal_n function_n and_o exercise_v of_o sense_n and_o motion_n in_o all_o the_o instrument_n and_o organ_n design_v by_o nature_n for_o those_o use_n furthermore_o it_o be_v very_o probable_a that_o the_o splenick_n ferment_n do_v by_o the_o artery_n out_o of_o the_o mass_n of_o blood_n supply_v the_o stomach_n and_o bowel_n which_o serve_v for_o the_o concoction_n of_o aliment_n with_o a_o menstruum_fw-la not_o unlike_o those_o liquor_n with_o which_o the_o chemist_n dissolve_v metal_n and_o other_o body_n for_o the_o dissolution_n of_o meat_n and_o reduce_v it_o to_o chyle_n for_o we_o can_v with_o reason_n assign_v that_o work_n to_o heat_n since_o the_o most_o intense_a fire_o can_v by_o roast_v bake_v boil_a or_o any_o other_o way_n of_o apply_v of_o that_o element_n reduce_v bread_n flesh_n and_o other_o meat_n in_o many_o day_n into_o a_o substance_n so_o fluid_a and_o thin_a as_o the_o stomach_n can_v in_o a_o very_a few_o hour_n now_o as_o the_o spleen_n while_o it_o dispense_v a_o sincere_a and_o right_o elaborate_v ferment_n be_v a_o bowel_v of_o great_a use_n and_o importance_n for_o the_o preservation_n of_o the_o blood_n and_o spirit_n in_o their_o due_a temper_n and_o motion_n so_o do_v it_o often_o cause_n very_o considerable_a disorder_n and_o extravagancy_n in_o the_o oeconomy_n of_o the_o body_n when_o it_o degenerate_v from_o its_o natural_a constitution_n and_o infect_v the_o humour_n and_o spirit_n with_o a_o impure_a and_o ill_o digest_v leven_n for_o that_o the_o blood_n may_v due_o and_o orderly_o ferment_n and_o circulate_a it_o be_v most_o requisite_a that_o the_o intestine_a motion_n of_o the_o little_a particle_n which_o constitute_v it_o be_v neither_o too_o furious_a and_o tumultuous_a nor_o too_o heavy_a and_o sluggish_a and_o for_o this_o reason_n be_v it_o as_o i_o suppose_v that_o the_o fix_a salt_n be_v separate_v from_o the_o blood_n in_o the_o spleen_n and_o again_o return_v and_o mingle_v with_o the_o mass_n by_o the_o vein_n for_o indeed_o fix_a salt_n consist_v of_o part_n which_o be_v endue_v with_o some_o kind_n of_o acrimony_n and_o yet_o be_v not_o too_o severe_o acid_a seem_v to_o be_v body_n most_o proper_a to_o maintain_v a_o leisurely_o and_o orderly_o ebullition_n but_o if_o the_o ferment_n once_o grow_v too_o sharp_a and_o acid_a and_o acquire_v part_n apt_a to_o provoke_v irritate_fw-la and_o prick_v the_o sensible_a part_n of_o the_o body_n and_o the_o fix_a salt_n become_v to_o be_v fluid_a it_o present_o fect_v the_o whole_a stream_n of_o the_o blood_n put_v it_o into_o violent_a and_o disorderly_a motion_n vellicate_v the_o nervous_a part_n fix_v the_o spirit_n put_v all_o the_o humour_n into_o a_o hurly_n burly_n and_o make_v they_o apt_a to_o congeal_v and_o stagnate_n for_o when_o this_o ferment_n be_v right_o make_v it_o consist_v of_o salt_n with_o the_o addition_n of_o a_o moderate_a quantity_n of_o earth_n by_o the_o mutual_a conjunction_n of_o which_o fix_a salt_n be_v produce_v but_o if_o by_o any_o mean_n there_o be_v a_o separation_n make_v of_o the_o saline_n part_n from_o the_o earthy_a then_o be_v the_o salt_n say_v to_o be_v in_o the_o state_n of_o fluidity_n because_o they_o run_v together_o into_o a_o liquor_n as_o spirit_n of_o salt_n spirit_n of_o vitriol_n and_o the_o like_a thus_o when_o the_o ferment_n of_o the_o spleen_n become_v fluid_a it_o acquire_v the_o fierce_a sharpness_n of_o vinegar_n or_o spirit_n of_o vitriol_n this_o be_v the_o fault_n of_o it_o in_o hypocondriacal_a person_n for_o in_o man_n who_o labour_v of_o those_o distemper_n all_o the_o fix_a salt_n of_o the_o blood_n which_o circulate_a through_o the_o spleen_n be_v there_o make_v fluid_a till_o at_o length_n they_o come_v to_o prevail_v over_o the_o other_o principle_n of_o the_o blood_n and_o turn_v the_o whole_a stock_n of_o it_o into_o a_o liquor_n as_o sharp_a as_o vinegar_n or_o spirit_n of_o vitriol_n by_o which_o mean_n all_o the_o spirit_n be_v depress_v and_o keep_v under_o the_o sour_a belch_v and_o vomit_n of_o hypocondriacal_a person_n which_o oftentimes_o be_v no_o less_o sharp_a than_o spirit_n of_o vitriol_n be_v a_o very_a sufficient_a argument_n of_o the_o sharpness_n of_o their_o juice_n which_o prick_n and_o tear_v their_o stomach_n bowel_n and_o nervous_a part_n with_o continual_a pain_n and_o torment_n and_o sometime_o with_o their_o corrode_a acidity_n flay_v their_o tongue_n throat_n and_o li_n and_o the_o violent_a and_o irregular_a motion_n and_o boiling_n of_o the_o blood_n do_v very_o evidendent_o convince_v that_o the_o constitution_n of_o that_o liquor_n in_o hypochondriacal_a person_n be_v become_v sharp_a and_o eager_a for_o we_o find_v it_o most_o true_a from_o sundry_a expriment_n that_o such_o tumultuous_a ebullition_n be_v cause_v from_o the_o mixture_n of_o fluid_a salt_n with_o fix_a and_o in_o liquor_n which_o be_v void_a of_o fluid_a salt_n we_o meet_v with_o no_o such_o fermentation_n or_o where_o they_o be_v but_o in_o small_a quantity_n mingle_v the_o fermentation_n be_v less_o and_o more_o leisurely_o and_o nothing_o so_o tumultuous_a in_o quicklime_n and_o juice_n which_o abound_v with_o acid_a salt_n as_o soon_o as_o the_o fluid_a and_o fix_v meet_v with_o one_o another_o present_o a_o noise_n heat_n and_o boil_a do_v ensue_v thus_o we_o see_v salt_n of_o wormwood_n scurvygrass_n or_o the_o like_a coral_n pearl_n oyster-shell_n and_o other_o testacious_a body_n when_o spirit_n of_o vitriol_n sulphur_n juice_n of_o lemon_n berbery_n orange_n or_o any_o acid_a liquor_n be_v pour_v upon_o they_o present_o fall_v a_o boil_a and_o hiss_v many_o more_o instance_n of_o this_o kind_n may_v be_v give_v but_o because_o they_o be_v obvious_a to_o every_o man_n who_o be_v in_o the_o least_o verse_v in_o chemical_a operation_n i_o will_v pass_v they_o by_o and_o far_a endeavour_n to_o prove_v from_o the_o way_n of_o cure_n of_o hypochondriacal_a distemper_n by_o the_o medicine_n most_o approve_v and_o fame_v by_o the_o best_a and_o most_o learned_a author_n that_o the_o cause_n of_o those_o affection_n consist_v in_o a_o sharp_a and_o eager_a distemper_n of_o the_o blood_n and_o juice_n the_o remedy_n which_o in_o this_o case_n be_v most_o commend_v be_v such_o as_o consist_v of_o steel_n tartar_n vitriol_n fix_a salt_n and_o all_o testacious_a body_n as_o likewise_o diuretical_a remedy_n which_o abound_v with_o fix_a salt_n do_v very_o much_o precipitate_v the_o blood_n for_o we_o find_v by_o experience_n that_o these_o medicine_n do_v sweeten_v all_o sharp_a liquor_n and_o abate_v their_o pungency_n for_o the_o acrimony_n of_o salt_n be_v not_o blunt_v by_o sulphurous_a but_o saline_n body_n by_o reason_n that_o fix_a salt_n by_o a_o intimate_a and_o close_a union_n to_o the_o fluid_a do_v obtund_v their_o point_n and_o edge_n as_o a_o thick_a piece_n of_o steel_n exact_o fit_v to_o the_o blade_n of_o a_o knife_n will_v abate_v the_o cut_n or_o divide_v power_n of_o the_o edge_n thus_o the_o corrode_a sharpness_n of_o spirit_n
of_o virriol_n be_v take_v away_o by_o salt_n of_o tartar_n or_o wormwood_n habet_fw-la say_v fonseca_n sal_fw-la tartari_fw-la magnam_fw-la vim_o domandi_fw-la humores_fw-la melancholicos_fw-la &_o atros_fw-la nam_fw-la trahit_fw-la ad_fw-la se_fw-la proprietate_fw-la quadam_fw-la accetositate_v &_o si_fw-la aceti_fw-la fortissimi_fw-la lb_fw-la iiii_o cum_fw-la â„¥_o i._n tartari_fw-la vini_fw-la destilletur_fw-la per_fw-la ignem_fw-la aqua_fw-la sine_fw-la ulla_fw-la aciditate_fw-la exibit_fw-la and_o true_o it_o be_v very_o probable_a that_o the_o reason_n why_o melancholy_a person_n find_v so_o much_o benefit_n from_o medicine_n of_o tartar_n be_v that_o by_o sweeten_v of_o the_o blood_n and_o juice_n after_o the_o same_o manner_n as_o that_o dulcify_v vinegar_n the_o tartar_n free_v the_o body_n from_o those_o inconvenience_n which_o be_v cause_v by_o their_o pungency_n and_o acrimony_n from_o this_o hypothesis_n a_o account_n may_v very_o rational_o be_v give_v why_o medicine_n of_o steel_n be_v use_v with_o very_o good_a success_n as_o well_o in_o cachectical_a and_o hydropical_a distemper_n in_o which_o usual_o the_o splenick_n ferment_n be_v deficient_a as_o in_o hypochondriacal_a and_o scorbutical_a disease_n in_o which_o that_o leven_n be_v too_o plentiful_o abound_v and_o too_o high_o exalt_v for_o the_o vitriolic_a salt_n of_o steel_n in_o which_o much_o of_o the_o force_n and_o virtue_n of_o that_o mineral_n reside_v be_v very_o proper_o substitute_v to_o supply_v the_o defect_n of_o a_o ferment_n to_o the_o blood_n and_o likewise_o the_o same_o salt_n when_o the_o blood_n be_v become_v sharp_a and_o eager_a and_o overcome_v by_o too_o large_a a_o quantity_n of_o fluid_a and_o acid_a salt_n do_v as_o salt_n of_o tartar_n work_v upon_o spirit_n of_o vitriol_n or_o vinegar_n abate_v its_o acrimony_n and_o sweeten_v the_o whole_a mass_n it_o may_v now_o be_v time_n that_o i_o shall_v more_o particular_o explain_v the_o manner_n how_o the_o blood_n and_o humour_n of_o the_o body_n by_o pass_v through_o the_o spleen_n do_v from_o that_o soft_a sweet_a and_o balsamic_a constitution_n which_o natural_o be_v in_o sound_n and_o healthy_a person_n degenerate_a into_o a_o liquor_n altogether_o harsh_a sharp_a and_o unpleasant_a to_o the_o nervous_a part_n of_o the_o body_n and_o for_o the_o better_a understanding_n of_o the_o way_n how_o this_o alteration_n be_v effect_v it_o be_v very_o necessary_a to_o look_v back_o to_o that_o description_n which_o i_o have_v in_o the_o begin_n of_o this_o discourse_n give_v of_o the_o make_n and_o fabric_n of_o the_o spleen_n to_o wit_n that_o the_o spleen_n consist_v of_o a_o great_a many_o artery_n not_o so_o many_o vein_n and_o of_o a_o multitude_n of_o fibrous_a thread_n upon_o which_o the_o parenchyma_n like_o clots_n of_o blood_n do_v everywhere_o stick_v fast_o leave_v little_a space_n or_o pore_n here_o and_o there_o intersperse_v between_o the_o part_n of_o it_o throughout_o the_o whole_a substance_n of_o that_o bowel_v i_o suppose_v then_o the_o little_a space_n or_o vacuity_n in_o the_o parenchyma_n of_o the_o spleen_n to_o be_v of_o such_o a_o figure_n and_o size_n as_o be_v unproportionable_a to_o the_o shape_n of_o the_o saline_a particle_n of_o the_o blood_n as_o long_o as_o any_o sulphur_n or_o phlegm_n stick_v to_o they_o and_o therefore_o they_o be_v not_o admit_v to_o pass_v along_o with_o the_o rest_n of_o the_o blood_n out_o of_o the_o artery_n into_o the_o vein_n but_o detain_v so_o long_o in_o the_o little_a cell_n or_o cavity_n of_o the_o spleen_n till_o by_o the_o frequent_a circulation_n of_o the_o blood_n and_o the_o collision_n and_o justle_a of_o the_o salt_n against_o the_o more_o solid_a part_n of_o the_o parenchyma_n they_o become_v free_a from_o the_o phlegm_n and_o sulphut_v which_o be_v join_v to_o they_o from_o which_o other_o principle_n as_o soon_o as_o they_o be_v disengage_v they_o do_v very_o ready_o and_o easy_o pass_v along_o with_o the_o blood_n which_o be_v circulate_v through_o the_o spleen_n as_o be_v then_o very_o suitable_a to_o the_o figure_n of_o the_o pore_n or_o passage_n to_o which_o as_o long_o as_o they_o be_v unite_v to_o those_o other_o principle_n they_o be_v not_o in_o the_o least_o agreeable_a the_o fix_a salt_n thus_o prepare_v in_o the_o spleen_n and_o pass_v from_o thence_o by_o the_o vein_n into_o the_o mass_n of_o blood_n serve_v to_o impregnate_n and_o ferment_n the_o liquor_n of_o the_o body_n and_o to_o preserve_v they_o in_o their_o due_a mixture_n and_o motion_n as_o long_o as_o the_o small_a passage_n in_o the_o spleen_n remain_v free_a and_o open_a and_o that_o the_o substance_n or_o parenchyma_n of_o it_o be_v not_o grow_v so_o hard_a and_o earthy_a as_o to_o alter_v the_o natural_a position_n and_o shape_n of_o the_o pore_n or_o little_a space_n in_o it_o the_o supply_n of_o a_o well_o prepare_v ferment_n to_o the_o blood_n be_v due_o and_o regular_o perform_v but_o if_o either_o from_o a_o natural_a melancholy_a constitution_n or_o error_n in_o dyer_n the_o substance_n of_o the_o spleen_n be_v render_v too_o compact_v solid_a and_o earthy_a and_o the_o pore_n or_o space_n be_v alter_v from_o their_o natural_a figure_n and_o magnitude_n the_o saline_a particle_n in_o their_o percolation_n through_o the_o spleen_n be_v so_o wear_v and_o grind_v that_o they_o be_v not_o only_o separate_v from_o the_o sulphur_n and_o phlegm_n which_o be_v necessary_a for_o the_o make_n of_o a_o fit_a ferment_n but_o likewise_o forcible_o disjoin_v from_o the_o earthy_a principle_n without_o which_o they_o can_v remain_v fix_v but_o present_o become_v fluid_a and_o then_o instead_o of_o a_o ferment_n which_o shall_v maintain_v in_o the_o blood_n and_o humour_n a_o orderly_a and_o moderate_a ebullition_n asharp_a eager_a and_o pungent_a liquor_n be_v send_v into_o the_o blood_n which_o put_v it_o into_o irregular_a and_o tumultuous_a fermentation_n and_o put_v the_o whole_a frame_n of_o the_o body_n into_o disorder_n that_o this_o be_v the_o fault_n of_o the_o spleen_n in_o hypochondriacal_a person_n seem_v to_o i_o the_o more_o probable_a for_o that_o it_o be_v observe_v that_o sar_n guin_a and_o phlegmatic_a complexion_n be_v very_o rare_o trouble_v with_o distemper_n of_o this_o nature_n and_o that_o even_o they_o who_o be_v natural_o of_o a_o melancholy_a temperament_n fall_v not_o into_o they_o before_o they_o arrive_v at_o a_o ripeness_n of_o age_n when_o the_o blood_n begin_v to_o be_v adust_a and_o the_o spleen_n to_o grow_v earthy_a and_o black_a whereas_o in_o those_o who_o be_v very_o young_a it_o be_v of_o a_o lively_a red_a colour_n it_o be_v worthy_a observation_n that_o this_o fault_n or_o disease_n of_o the_o spleen_n be_v seldom_o or_o never_o perfect_o cure_v and_o therefore_o the_o best_a medicine_n do_v only_o by_o sweeten_v the_o blood_n so_o long_o allay_v the_o symptom_n and_o disorder_n of_o it_o till_o the_o mass_n become_v again_o infect_v with_o acidity_n from_o the_o spleen_n and_o therefore_o person_n who_o have_v be_v once_o trouble_v with_o hypochondriacal_a distemper_n do_v usual_o periodical_o relapse_n into_o they_o from_o hence_o it_o will_v be_v no_o very_o hard_a matter_n to_o give_v a_o account_n of_o the_o cause_n of_o the_o particular_a symptom_n and_o accident_n which_o accompany_v the_o hypochondriacal_a distemper_n they_o concern_v either_o the_o natural_a vital_a or_o animal_n faculty_n as_o to_o the_o natural_a the_o appetite_n to_o meat_n be_v often_o by_o reason_n of_o the_o sharpness_n of_o the_o ferment_n in_o the_o stomach_n too_o extravagant_a and_o yet_o the_o meat_n be_v ill_o digest_v and_o much_o of_o it_o turn_v sometime_o into_o a_o sour_a water_n at_o other_o into_o tough_a slime_n by_o reason_n that_o the_o extraordinary_a sharpness_n of_o the_o ferment_n make_v it_o unproportionable_a and_o unfit_a to_o dissolve_v the_o aliment_n for_o that_o this_o may_v happen_v upon_o such_o a_o score_n the_o observation_n of_o the_o chemist_n do_v sufficient_o evince_v who_o find_v pisan_n berigard_n circ_n pisan_n menstruum_fw-la nimis_fw-la acidum_fw-la metallum_fw-la suum_fw-la non_fw-la solvere_fw-la from_o the_o same_o cause_n they_o who_o labour_n of_o this_o distemper_n be_v trouble_v with_o continual_a spit_v loathe_a and_o sometime_o vomit_v the_o stomach_n be_v provoke_v and_o convel_v by_o the_o gnaw_a acidity_n of_o its_o menstruum_fw-la they_o be_v usual_o hard-bound_a in_o their_o body_n and_o seldom_o go_v to_o stool_n partly_o by_o reason_n that_o the_o passage_n from_o the_o gall_n be_v obstruct_v one_o use_n of_o choler_n be_v to_o irritate_fw-la the_o gut_n and_o cause_v they_o to_o thrust_v out_o their_o excrement_n and_o partly_o for_o that_o the_o pancreas_n as_o riverius_n observe_v be_v usual_o affect_v in_o this_o distemper_n and_o do_v not_o furnish_v the_o gut_n with_o a_o ferment_n for_o it_o be_v very_o probable_a that_o by_o wirsungius_n his_o passage_n a_o liquor_n be_v send_v into_o
mercurius_n politicus_fw-la the_o author_n of_o medela_fw-la and_o his_o book_n be_v so_o inconsiderable_a that_o they_o deserve_v not_o to_o be_v treat_v with_o any_o respect_n especial_o since_o himself_o so_o inhuman_o trample_v upon_o the_o ash_n of_o the_o ancient_n at_o that_o wild_a rate_n fling_v dirt_n upon_o the_o learn_a society_n of_o physician_n in_o the_o world_n and_o libel_n the_o university_n not_o only_o in_o his_o book_n but_o in_o his_o pretension_n to_o have_v have_v his_o education_n in_o they_o yet_o my_o design_n be_v not_o so_o much_o to_o concern_v myself_o in_o the_o man_n or_o his_o scurrilous_a expression_n as_o to_o take_v occasion_n from_o those_o material_a point_n in_o physic_n which_o he_o have_v very_o idle_o and_o extravagant_o state_v to_o treat_v of_o they_o more_o close_o and_o pertinent_o according_a to_o the_o best_a and_o true_a ground_n of_o philosophy_n and_o physic_n sir_n i_o have_v so_o far_o presume_v upon_o your_o friendship_n as_o not_o only_o to_o trouble_v you_o with_o the_o read_n but_o countenance_v of_o this_o treatise_n if_o it_o be_v not_o suitable_a to_o the_o advantage_n which_o i_o may_v very_o well_o have_v receive_v from_o a_o long_a acquaintance_n with_o you_o your_o converse_n be_v as_o diffusive_a of_o knowledge_n as_o it_o be_v of_o kindness_n pray_v believe_v that_o i_o have_v mind_v more_o the_o be_v just_a to_o my_o promise_n than_o careful_a of_o my_o credit_n sir_n i_o be_o westmin_n martii_fw-la 10._o 1666._o your_o most_o oblige_a friend_n and_o humble_a servant_n george_n castle_n errata_fw-la page_n 14._o line_n 24._o insert_v to_o p._n 22._o l._n 7._o for_o impart_v read_v invent_v p._n 35._o l._n 10._o for_o lixivat_a r._n lixiviat_fw-la p._n 38._o l._n 2._o for_o stomocace_n r._n stomacace_n p._n 46._o l._n 2._o leave_v out_o dead_a of_o the_o consumption_n p._n 72._o l._n 23._o for_o worlp_n r._n world_n p._n 73._o l._n 8._o for_o often_o escue_n r._n often_o rescue_n p._n 79._o l._n 24._o for_o canprobaolybe_n r._n can_v probable_o be_v p._n 89._o l._n 12._o insert_v shall_v p._n 100_o l._n 12._o leave_v out_o they_o p._n 104._o l._n 6._o for_o disease_n r._n disease_n p._n 115._o l._n 24._o for_o evaporate_v r._n evaporate_n p._n 133._o l._n 1._o for_o cane_n r._n cave_n p._n 43._o l._n 30._o leave_v out_o be_v p._n 44._o l._n 27._o for_o procatactick_a r._n procotarctick_a leave_v out_o the_o second_o its_o ibid._n p._n 160._o l._n â—5_n for_o and_o r._n in_o p._n 169._o l._n 9_o insert_v he_o p._n 172._o l._n 29._o for_o manichaearum_fw-la r._n manichaeorum_fw-la p._n 175._o l._n 19_o for_o this_o r._n his_o for_o other_o fault_n which_o have_v pass_v the_o press_n i_o desire_v the_o reader_n be_v courteous_a correction_n the_o chemical_a galenist_n chap._n i._n that_o there_o have_v be_v make_v of_o late_a very_o considerable_a discovery_n in_o physic_n that_o the_o art_n be_v yet_o far_a improvable_a and_o that_o the_o galenick_n hypothesis_n be_v insufficient_a to_o give_v a_o satisfactory_a account_n of_o the_o phaenomena_n of_o health_n and_o disease_n be_v no_o more_o news_n to_o this_o age_n than_o that_o america_n be_v find_v out_o that_o some_o part_n of_o the_o world_n be_v yet_o unknown_a and_o that_o the_o ancient_a map_n be_v imperfect_a neither_o be_v this_o less_o question_v by_o gâ—ographers_n than_o the_o other_o by_o philosopher_n and_o physician_n wherefore_o in_o my_o opinion_n the_o author_n of_o medela_fw-la aught_o to_o have_v be_v more_o civil_a to_o those_o sound_a author_n of_o who_o to_o compile_v a_o book_n he_o do_v every_o where_o more_o than_o borrow_v then_o to_o make_v they_o speak_v to_o no_o purpose_n in_o his_o writing_n who_o do_v always_o to_o so_o much_o in_o their_o own_o for_o he_o may_v with_o no_o less_o extravagancy_n have_v infer_v from_o columbus_n his_o discovery_n in_o the_o great_a world_n that_o it_o will_v be_v for_o the_o interest_n of_o all_o kingdom_n and_o commonwealth_n to_o furnish_v every_o pretender_n to_o navigation_n though_o never_o so_o ignorant_a with_o ship_n man_n and_o money_n in_o hope_n he_o may_v find_v out_o new_a country_n than_o from_o the_o famous_a harvy_v or_o learned_a willis_n in_o the_o lesser_a world_n that_o it_o be_v for_o the_o benefit_n of_o mankind_n that_o the_o life_n and_o purse_n of_o man_n shall_v lie_v expose_v to_o the_o cheat_n of_o ignorant_a pretender_n to_o physic_n upon_o presumption_n that_o they_o may_v find_v out_o new_a region_n new_a flood_n and_o channel_n in_o the_o microcosm_n but_o to_o persuade_v the_o world_n that_o he_o and_o his_o brethren_n the_o mountebank_n be_v the_o only_a man_n from_o who_o physic_n be_v to_o expect_v a_o far_a improvement_n he_o endeavour_v to_o render_v all_o those_o physician_n who_o have_v more_o learning_n and_o modesty_n than_o himself_o as_o man_n whole_o enslave_v to_o narrow_a principle_n and_o jejune_n notion_n and_o altogether_o confine_v to_o a_o beat_a and_o trite_a road_n in_o philosophy_n and_o physic_n as_o be_v enemy_n to_o all_o advancement_n of_o knowledge_n which_o be_v a_o falsehood_n so_o notorious_a and_o obvious_a to_o be_v confute_v that_o i_o need_v only_o to_o examine_v who_o have_v be_v the_o author_n of_o the_o waste_n improvement_n of_o physic_n which_o m._n n._n himself_o acknowledge_v to_o have_v be_v in_o twenty_o year_n so_o heighten_v 215._o m._n del_fw-it med._n p._n 215._o that_o never_o any_o science_n or_o art_n in_o the_o world_n have_v such_o a_o advance_v and_o alteration_n in_o so_o short_a a_o time_n i_o use_v his_o own_o word_n and_o it_o will_v appear_v that_o the_o world_n be_v indebt_v to_o the_o true_a artist_n rational_a physician_n learned_a man_n and_o not_o to_o the_o medicastrorum_fw-la empiricorum_fw-la medicantiumque_fw-la 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d 〈◊〉_d the_o dregs_o and_o scum_n of_o mankind_n 37._o johaâ—_n rodolph_n camâ—râ—r_n memor_n med._n centur._n 1_o po_n 37._o as_o camerarius_fw-la call_v they_o to_o who_o i_o will_v refer_v the_o reader_n for_o a_o far_a account_n of_o those_o precious_a son_n of_o art_n as_o desire_v myself_o to_o be_v so_o civil_a to_o the_o author_n of_o medela_fw-la as_o not_o to_o give_v a_o catalogue_n of_o that_o goodly_a pack_n of_o his_o brotherhood_n to_o show_v that_o the_o improvement_n which_o physic_n have_v receive_v in_o this_o latter_a age_n aught_o to_o be_v ascribe_v to_o the_o learned_a physician_n and_o man_n breed_v up_o in_o university_n and_o college_n i_o need_v go_v no_o further_o for_o instance_n than_o in_o our_o own_o nation_n and_o the_o rather_o because_o i_o believe_v that_o foreigner_n themselves_o will_v confess_v we_o to_o have_v far_o outdo_v the_o whole_a world_n in_o this_o matter_n witness_v the_o write_n of_o the_o renown_a harvey_n the_o learned_a doctor_n glisson_n ent_n highmore_n wharton_n and_o the_o present_a ornament_n both_o of_o his_o university_n and_o nation_n dr._n willis_n for_o notwithstanding_o that_o m._n n._n and_o some_o other_o touchy-head_n 17._o medel_n med._n p._n 17._o as_o he_o call_v they_o like_o his_o have_n pry_v into_o one_o point_n viz._n whether_o in_o the_o practice_n of_o physic_n there_o need_v be_v the_o hundred_o part_n of_o ado_n about_o the_o anatomy_n especial_o see_v that_o when_o the_o body_n be_v out_o of_o order_n by_o disease_n the_o blood_n and_o humour_n have_v other_o vagary_n than_o in_o their_o usual_a channel_n by_o his_o good_a favour_n the_o great_a advantage_n which_o have_v accrue_v both_o to_o the_o theory_n and_o practice_n of_o physic_n in_o these_o late_a year_n must_v necessary_o be_v acknowledge_v to_o have_v proceed_v from_o the_o discovery_n which_o have_v be_v make_v in_o anatomy_n and_o that_o dog_n pig_n and_o monkey_n have_v contribute_v more_o to_o the_o advancement_n of_o physic_n than_o m._n n._n and_o his_o fraternity_n ever_o do_v or_o be_v like_a to_o do_v though_o it_o must_v be_v confess_v his_o endeavour_n have_v not_o be_v want_v to_o be_v a_o benefactor_n to_o the_o surgeon_n hall_n and_o possible_o be_v conscious_a that_o he_o may_v be_v more_o serviceable_a to_o physic_v dead_a than_o alive_a there_o be_v a_o time_n when_o he_o bid_v as_o fair_a for_o the_o knife_n as_o any_o man_n pol._n with_fw-mi a_o rope_n for_o pol._n it_o be_v i_o say_v from_o the_o accurate_a inspection_n into_o body_n in_o which_o of_o late_a physician_n have_v be_v wonderful_o curious_a and_o industrious_a that_o physic_n have_v attain_v to_o that_o wonderful_a height_n for_o since_o the_o circulation_n of_o the_o blood_n have_v be_v find_v out_o by_o doctor_n harvey_n that_o be_v lay_v as_o a_o new_a foundation_n the_o whole_a fabric_n have_v be_v build_v from_o the_o very_a ground_n the_o part_n of_o the_o body_n as_o to_o their_o figure_n site_n relation_n vessel_n texture_n magnitude_n connexion_n and_o correspondency_n have_v be_v
common_a amber_n as_o to_o child_n but_o not_o grow_v person_n i_o do_v not_o urge_v this_o to_o discourage_v any_o person_n from_o inquire_v into_o the_o nature_n of_o simple_n which_o certain_o be_v a_o laudable_a industry_n but_o to_o show_v that_o it_o be_v not_o so_o easy_a as_o the_o author_n of_o medela_fw-la will_v make_v it_o to_o impart_v remedy_n they_o be_v not_o in_o the_o least_o matter_n of_o fancy_n and_o that_o such_o medicine_n which_o have_v be_v establish_v by_o the_o long_a experience_n of_o the_o inquire_n and_o judicious_a part_n of_o the_o world_n by_o whole_a college_n and_o university_n who_o have_v make_v it_o the_o business_n of_o their_o life_n to_o inform_v themselves_o and_o other_o be_v not_o easy_o to_o be_v lay_v aside_o for_o those_o which_o have_v be_v invent_v by_o some_o ignorant_a man_n nay_o possible_o a_o know_v one_o till_o they_o by_o undergo_a the_o same_o test_n of_o experience_n be_v allow_v by_o that_o to_o be_v more_o effectual_a and_o less_o inconvenient_a in_o all_o case_n whatsoever_o history_n be_v full_a of_o the_o frequent_a tragedy_n which_o have_v be_v act_v by_o mountebank_n in_o administer_a medicine_n who_o nature_n and_o power_n they_o understand_v not_o about_o two_o year_n since_o have_v visit_v my_o honour_a learned_a friend_n dr._n cox_n physician_n in_o ordinary_a to_o his_o majesty_n he_o acquaint_v i_o that_o he_o have_v be_v late_o call_v to_o a_o citizen_n of_o london_n who_o upon_o take_v a_o vomit_n from_o a_o empiric_n and_o a_o hypercatharsis_n ensue_v upon_o it_o fall_v into_o dismal_a convulsion_n in_o which_o in_o despite_n of_o the_o most_o proper_a remedy_n he_o die_v i_o do_v not_o wonder_v that_o these_o sad_a effect_n do_v often_o follow_v upon_o the_o take_n of_o physic_n from_o ignorant_a man_n for_o the_o universal_a medicine_n of_o the_o empiric_n being_n usual_o some_o or_o other_o ill_a preparation_n of_o antimony_n in_o substance_n if_o it_o chance_v not_o to_o pass_v upward_o or_o downward_o but_o stick_v in_o the_o coat_n of_o the_o stomach_n or_o be_v entangle_v in_o some_o tough_a viscous_a matter_n it_o be_v the_o nature_n of_o that_o mineral_n to_o communicate_v a_o vomit_v quality_n after_o it_o have_v impregnate_v several_a infusion_n no_o wonder_n if_o lie_v in_o the_o stomach_n it_o continual_o impart_v to_o the_o juice_n which_o flow_v thither_o out_o of_o the_o mass_n of_o blood_n for_o a_o menstruum_fw-la to_o dissolve_v the_o meat_n and_o to_o those_o liquor_n which_o be_v take_v in_o by_o the_o mouth_n a_o emetic_n virtue_n till_o the_o patient_n at_o length_n have_v vomit_v up_o his_o soul_n upon_o this_o score_n i_o do_v not_o find_v that_o many_o physician_n be_v very_o forward_o in_o use_v mercurius_n vitæ_fw-la especial_o in_o pill_n or_o a_o solid_a form_n which_o though_o i_o have_v use_v and_o see_v use_v with_o good_a success_n yet_o i_o judge_v it_o give_v in_o substance_n not_o so_o safe_a and_o nothing_o more_o effectual_a than_o the_o infusion_n of_o that_o excellent_a good_a preparation_n of_o antimony_n crocus_n metallorum_fw-la which_o though_o it_o be_v to_o be_v meet_v with_o in_o the_o road_n of_o dispensatories_n with_o m._n n_n good_a leave_n be_v no_o contemptible_a medicine_n how_o much_o in_o medicine_n experience_n be_v to_o be_v value_v and_o how_o like_o a_o toleration_n of_o assassinate_v it_o will_v look_v to_o allow_v a_o liberty_n to_o every_o quack_n to_o make_v experiment_n upon_o man_n body_n will_v far_o appear_v if_o we_o consider_v that_o the_o mix_n of_o thing_n harmless_a in_o themselves_o may_v sometime_o produce_v a_o poison_n thus_o out_o of_o vitriol_n salt_n mercury_n and_o niter_n be_v make_v sublimate_n of_o vitriol_n niter_n and_o alum_n aqua_fw-la fortis_fw-la which_o though_o make_v of_o innocent_a ingredient_n be_v mixture_n most_o destructive_a to_o the_o body_n of_o man._n and_o i_o know_v not_o why_o in_o other_o mixture_n the_o same_o thing_n may_v not_o come_v to_o pass_v which_o may_v never_o be_v consider_v by_o a_o bold_a and_o unwary_a experimenter_n of_o medicine_n nor_o know_v but_o at_o the_o price_n of_o a_o murder_n in_o the_o next_o place_n there_o be_v a_o absolute_a necessity_n that_o he_o who_o will_v venture_v to_o give_v physic_n be_v able_a to_o judge_v of_o the_o strength_n and_o constitution_n of_o the_o sick_a person_n who_o he_o undertake_v if_o he_o expect_v with_o safety_n and_o success_n to_o manage_v the_o matter_n plutarch_n in_o a_o dialogue_n introduce_v phaedrius_n and_o socrates_n discourse_v to_o this_o purpose_n socrat_n if_o any_o one_o shall_v tell_v i_o true_o i_o know_v how_o to_o apply_v these_o thing_n to_o the_o body_n with_o which_o i_o can_v when_o i_o please_v make_v it_o hot_a or_o cold_a vomit_n and_o purge_v and_o cause_v other_o evacuation_n upon_o the_o understanding_n of_o which_o i_o profess_v myself_o a_o physician_n and_o affirm_v that_o any_o man_n instruct_v with_o this_o knowledge_n may_v be_v one_o what_o answer_v do_v you_o think_v a_o sober_a man_n will_v return_v to_o he_o phaedr_n true_o none_o at_o all_o but_o ask_v he_o whether_o he_o likewise_o understand_v to_o who_o and_o when_o and_o in_o what_o proportion_n every_o one_o of_o these_o medicine_n be_v to_o be_v give_v of_o which_o if_o he_o be_v ignorant_a the_o man_n must_v certain_o be_v mad_a who_o upon_o the_o score_n either_o of_o glean_n from_o author_n or_o for_o have_v be_v present_a at_o the_o cure_n of_o some_o physician_n and_o understand_v nothing_o of_o the_o art_n think_v he_o be_v present_o become_v a_o physician_n many_o excellent_a and_o in_o the_o hand_n of_o artist_n most_o safe_a medicine_n have_v suffer_v in_o their_o credit_n by_o fall_v into_o the_o hand_n of_o such_o person_n who_o either_o by_o over-dosing_a or_o not_o suit_v they_o to_o the_o temper_n age_n and_o sex_n of_o their_o patient_n have_v with_o they_o kill_v instead_o of_o cure_v 13._o sennert_n de_fw-fr con._n &_o dissent_n chym._n cum_fw-la gal._n c._n 13._o sennertus_n tell_v we_o that_o he_o know_v two_o child_n kill_v by_o two_o old_a woman_n with_o oil_n of_o amber_n one_o of_o the_o child_n be_v scarce_o ten_o day_n old_a after_o the_o woman_n have_v give_v it_o some_o drop_n of_o oil_n of_o amber_n break_v out_o all_o over_o the_o body_n as_o if_o scald_a water_n have_v be_v pour_v upon_o it_o and_o present_o dye_v the_o other_o more_o adult_n have_v take_v the_o same_o oil_n die_v vomit_v and_o scour_v that_o very_o safe_a and_o effectual_a remedy_n mercurius_n dulcis_fw-la so_o often_o celebrate_v in_o riverius_n under_o the_o name_n of_o calomelanos_fw-la a_o name_n put_v upon_o it_o by_o sir_n theodore_n mayern_n from_o one_o faire-black_a his_o man_n who_o use_v to_o prepare_v it_o as_o i_o find_v it_o in_o his_o letter_n to_o my_o father_n have_v in_o the_o give_n of_o it_o to_o some_o body_n and_o constitution_n be_v accompany_v with_o very_o ill_a accident_n sennertus_n tell_v of_o a_o learned_a physician_n a_o friend_n of_o his_o who_o have_v often_o give_v mercurius_n dulcis_fw-la to_o his_o patient_n with_o very_a good_a success_n 18._o sennert_n de_fw-fr con._n &_o dissent_n chym._n come_v gal._n c._n 18._o and_o yet_o be_v in_o danger_n to_o have_v dye_v by_o the_o take_n of_o it_o himself_o and_o i_o have_v observe_v that_o this_o medicine_n do_v best_a agree_v with_o those_o who_o stomach_n abound_v with_o crudity_n as_o child_n and_o not_o so_o well_o with_o those_o person_n who_o stomach_n and_o blood_n abound_v with_o fluid_a salt_n and_o be_v trouble_v with_o acidity_n and_o sharpness_n of_o their_o liquor_n for_o mercurius_n dulcis_fw-la be_v make_v of_o sublimate_n corrosive_n and_o quicksilver_n by_o the_o sublime_a of_o which_o together_o the_o sharp_a edge_n of_o the_o corrosive_a salt_n be_v blunt_v and_o abate_v and_o so_o the_o medicine_n sweeten_v and_o make_v harmless_a there_o be_v danger_n that_o in_o the_o stomach_n which_o abound_v with_o vitriolic_a salt_n for_o some_o i_o have_v see_v who_o vomit_n will_v gnaw_v iron_n the_o dulcify_v mercury_n may_v again_o be_v reduce_v to_o be_v corrosive_a in_o the_o last_o place_n that_o a_o disease_n must_v be_v know_v before_o it_o can_v be_v cure_v be_v so_o general_o receive_v a_o maxim_n that_o it_o be_v become_v proverbial_a with_o the_o vulgar_a that_o the_o knowledge_n of_o the_o disease_n be_v half_a the_o cure_n what_o skill_n in_o anatomy_n and_o philosophy_n be_v require_v to_o the_o knowledge_n of_o disease_n i_o have_v already_o discourse_v to_o which_o if_o i_o shall_v add_v the_o doctrine_n of_o pulse_n urine_n and_o all_o other_o semeiotick_v it_o will_v not_o appear_v so_o easy_a a_o thing_n to_o understand_v the_o several_a distemper_n of_o the_o body_n of_o man_n that_o it_o may_v be_v presume_v that_o every_o old_a woman_n
i_o will_v tell_v he_o what_o dr._n harvey_n say_v upon_o this_o point_n 51._o hâ—rv_n de_fw-fr gen._n an._n ex._n 51._o but_o while_o i_o affirm_v say_v that_o oracle_n the_o soul_n to_o reside_v first_o and_o principal_o in_o the_o blood_n i_o will_v not_o have_v any_o man_n hasty_o to_o conclude_v from_o hence_o that_o all_o blood_n let_v be_v dangerous_a or_o hurtful_a or_o believe_v with_o the_o vulgar_a that_o as_o much_o blood_n so_o much_o life_n be_v take_v away_o because_o holy_a writ_n place_v the_o life_n in_o the_o blood_n for_o daily_a experience_n show_v that_o let_a blood_n be_v a_o safe_a cure_n for_o several_a disease_n and_o the_o chief_a of_o universal_a remedy_n because_o the_o default_n or_o superfluity_n of_o the_o blood_n be_v the_o seminary_n of_o most_o distemper_n and_o a_o seasonable_a evacuation_n of_o it_o do_v oftenescue_v man_n from_o most_o desperate_a malady_n and_o even_a death_n itself_o for_o look_v how_o much_o blood_n be_v according_a to_o art_n take_v away_o so_o many_o year_n be_v add_v to_o the_o age_n nature_n herself_o be_v our_o tutor_n here_o who_o physician_n transcribe_v for_o she_o of_o her_o own_o accord_n do_v many_o time_n vanquish_v the_o most_o mortal_a infirmity_n by_o a_o plentiful_a and_o critical_a evacuation_n either_o by_o the_o nose_n haemorrhoid_v or_o by_o menstruous_a purgation_n and_o therefore_o young-people_n who_o feed_v high_a and_o live_v idle_o unless_o about_o the_o eighteen_o or_o twenty_o year_n of_o their_o age_n at_o which_o time_n the_o stock_n of_o blood_n increase_v together_o with_o the_o bulk_n of_o their_o body_n be_v disburden_v of_o the_o load_n and_o oppression_n of_o their_o blood_n either_o by_o a_o spontaneous_a release_n at_o the_o nose_n or_o inferior_a part_n or_o by_o breathe_v a_o vein_n they_o be_v dangerous_o set_v upon_o by_o fevour_n small_a pox_n headache_n and_o other_o more_o grievous_a didistemper_n and_o symptom_n allude_v to_o which_o the_o farrier_n do_v begin_v 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pain_n in_o no_o part_n of_o his_o body_n not_o have_v the_o use_n of_o any_o of_o his_o limb_n though_o he_o where_o a_o person_n who_o these_o many_o year_n have_v be_v high_o scorbutical_a we_o draw_v from_o he_o at_o least_o the_o quantity_n of_o 70_o â„¥_o of_o blood_n before_o we_o can_v free_v he_o from_o pain_n and_o restore_v he_o to_o his_o health_n platerus_n make_v mention_n of_o a_o madwoman_n 80._o plat._n obs_n l._n 1._o p._n 80._o who_o be_v cure_v by_o be_v let_v blood_n in_o several_a vein_n seventy_o time_n in_o one_o week_n i_o may_v run_v through_o all_o other_o disease_n and_o show_v the_o necessity_n of_o bleed_a which_o may_v happen_v in_o most_o of_o they_o but_o because_o m._n n_o '_o s._n main_a argument_n be_v found_v upon_o sanguification_n i_o will_v endeavour_v to_o explain_v how_o the_o chyle_n be_v turn_v into_o blood_n and_o in_o what_o part_n of_o the_o body_n chief_o this_o work_n be_v effect_v so_o that_o by_o discover_v the_o true_a way_n of_o sanguification_n his_o argument_n may_v appear_v to_o be_v ill_o ground_v that_o the_o liver_n be_v not_o the_o shop_n wherein_o the_o blood_n be_v make_v be_v evident_a to_o any_o man_n who_o will_v examine_v the_o generation_n of_o animal_n for_o 207._o harv_n de_fw-fr gen._n exit_fw-la 18._o p._n 63._o ex._n 50._o p._n 153._o ex._n 59_o p._n 207._o he_o shall_v perceive_v the_o heart_n beat_v and_o blood_n perfect_o colour_v before_o there_o appear_v any_o rudiment_n of_o the_o liver_n so_o that_o the_o liver_n be_v make_v after_o the_o blood_n and_o as_o it_o be_v stick_v upon_o little_a slender_a thread_n and_o the_o parenchyma_n of_o it_o evident_o grow_v out_o of_o the_o mouth_n of_o the_o artery_n through_o which_o matter_n be_v supply_v to_o the_o formation_n of_o it_o so_o that_o the_o parenchyma_n of_o it_o seem_v to_o be_v nothing_o else_o but_o congeal_a blood_n again_o the_o chyle_n never_o go_v to_o the_o liver_n but_o empty_v itself_o into_o the_o subclavial_a vein_n and_o go_v straight_o away_o to_o the_o right_a ventricle_n of_o the_o heart_n now_o the_o use_n and_o business_n of_o the_o liver_n 41._o glisson_n anat._n hep._n c._n 41._o be_v without_o doubt_n that_o which_o be_v assign_v by_o the_o eminent_o learn_v d._n glisson_n that_o it_o be_v make_v to_o receive_v the_o blood_n which_o run_v to_o it_o by_o the_o porta_n to_o separate_v the_o choler_n from_o it_o and_o then_o be_v free_v from_o that_o to_o deliver_v it_o to_o the_o cava_fw-la the_o very_a make_n and_o structure_n of_o that_o bowel_v argue_v as_o much_o as_o also_o the_o distribution_n of_o the_o vessel_n to_o every_o part_n of_o the_o parenchyma_n for_o the_o porta_n equal_o dispense_v the_o blood_n into_o all_o part_n of_o it_o and_o the_o small_a capillary_a thread_n of_o the_o porus_n biliarius_n be_v every_o where_o disperse_v and_o ready_a to_o receive_v the_o choler_n which_o be_v bring_v along_o mingle_v with_o the_o blood_n into_o every_o part_n and_o in_o like_a manner_n the_o small_a branch_n of_o the_o vena_fw-la cava_fw-la be_v every_o where_o interwoven_a and_o at_o hand_n to_o carry_v away_o the_o blood_n when_o cleanse_v and_o free_v from_o the_o bilious_a part_n of_o it_o now_o the_o choler_n be_v separate_v from_o the_o blood_n by_o a_o certain_a kind_n of_o percolation_n for_o the_o blood_n issue_v out_o from_o the_o porta_n into_o the_o parenchyma_n or_o fleshy_a part_n of_o the_o liver_n find_v that_o substance_n full_a of_o pore_n or_o little_a space_n of_o divers_a shape_n and_o figure_n and_o proportionable_a to_o the_o shape_n size_n and_o figuration_n of_o the_o particle_n or_o atom_n of_o blood_n and_o choler_n whereof_o those_o which_o be_v suitable_a to_o the_o shape_n of_o the_o part_n of_o choler_n open_a into_o the_o small_a pipe_n of_o the_o porus_n biliarius_fw-la those_o which_o be_v answerable_a to_o the_o shape_n of_o the_o atom_n of_o blood_n convey_v it_o into_o the_o little_a mouth_n of_o the_o cava_fw-la these_o pore_n or_o little_a hole_n easy_o let_v pass_v those_o part_n of_o matter_n which_o be_v correspondent_a to_o their_o shape_n but_o refuse_v all_o of_o another_o figure_n as_o we_o see_v water_n will_v dissolve_v common_a salt_n and_o imbibe_n it_o so_o long_o till_o all_o the_o space_n which_o agree_v with_o the_o shape_n of_o it_o be_v fill_v and_o then_o will_v receive_v no_o more_o but_o yet_o afterward_o will_v receive_v sugar_n or_o salt_n of_o another_o figure_n so_o long_o till_o they_o have_v fill_v the_o space_n suitable_a to_o their_o shape_n the_o separation_n of_o choler_n in_o the_o liver_n may_v not_o unfit_o be_v explain_v by_o that_o which_o be_v make_v in_o sieve_n whereof_o some_o be_v make_v only_o to_o sever_v chaff_n and_o dust_n some_o for_o fetch_n some_o for_o barley_n other_o for_o oat_n which_o according_a to_o the_o shape_n of_o the_o hole_n let_v pass_v or_o refuse_v this_o or_o the_o other_o grain_n have_v thus_o explain_v the_o anatomy_n of_o the_o liver_n i_o will_v proceed_v to_o discourse_v of_o the_o nature_n of_o blood_n itself_o and_o the_o principal_a engine_n which_o be_v employ_v in_o the_o make_n of_o it_o and_o to_o that_o end_n let_v i_o trace_v the_o passage_n of_o the_o chyle_n that_o we_o may_v the_o better_o find_v when_o and_o where_o it_o be_v turn_v to_o blood_n it_o be_v well_o know_v to_o every_o man_n who_o have_v but_o in_o any_o measure_n inquire_v into_o physic_n and_o anatomy_n nerv_n willis_n descript_n nerv_n that_o as_o soon_o as_o the_o meat_n be_v dissolve_v by_o the_o menstruum_fw-la of_o the_o stomach_n it_o be_v press_v down_o into_o the_o gut_n and_o out_o of_o they_o all_o the_o way_n almost_o to_o the_o very_a anus_fw-la the_o thin_a and_o fine_a part_n be_v force_v into_o the_o lacteal_v out_o of_o which_o it_o
be_v deliver_v into_o the_o common_a channel_n of_o the_o chyle_n and_o be_v mingle_v with_o a_o whey_n which_o come_v out_o of_o the_o lymphaticks_n it_o enter_v the_o subclavial_o out_o of_o which_o it_o run_v mingle_v with_o the_o blood_n into_o the_o great_a trunk_n of_o the_o vena_fw-la cava_fw-la out_o of_o which_o pass_v into_o the_o right_a ventricle_n of_o the_o heart_n by_o the_o motion_n of_o that_o engine_n through_o the_o pulmonary_a artery_n it_o be_v fling_v into_o the_o lung_n out_o of_o which_o have_v there_o separate_v some_o phlegmatic_a or_o crude_a excrement_n and_o be_v impregnate_v with_o the_o nitre_n of_o the_o air_n which_o be_v draw_v in_o by_o respiration_n and_o be_v in_o the_o lung_n as_o with_o a_o churn_n or_o chocolate-mill_n more_o exact_o mingle_v with_o the_o blood_n it_o hasten_v by_o the_o pulmonary_a vein_n to_o the_o left_a ventricle_n of_o the_o heart_n out_o of_o which_o by_o the_o aorta_fw-mi it_o be_v send_v to_o all_o the_o part_n of_o the_o body_n thus_o far_o the_o chyle_n may_v be_v easy_o trace_v and_o true_o i_o know_v not_o why_o it_o may_v not_o have_v pass_v the_o last_o deflagration_n in_o the_o heart_n be_v just_o call_v blood_n i_o will_v not_o in_o this_o place_n bring_v the_o distinction_n of_o the_o school_n upon_o the_o stage_n which_o distinguish_v that_o liquor_n which_o run_v in_o the_o vein_n and_o artery_n into_o three_o humour_n and_o blood_n as_o be_v now_o out_o of_o door_n with_o all_o ingenious_a man_n and_o be_v no_o otherwise_o to_o be_v apply_v than_o as_o some_o portion_n of_o that_o liquor_n have_v more_o often_o other_o more_o seldom_o or_o hardly_o yet_o at_o all_o pass_v through_o the_o heart_n and_o there_o be_v fire_v but_o i_o in_o general_a term_v all_o those_o juice_n blood_n which_o run_v in_o the_o vein_n and_o artery_n and_o have_v the_o form_n colour_n and_o consistence_n of_o that_o liquor_n which_o be_v vulgar_o call_v so_o though_o it_o consist_v as_o certain_o all_o blood_n do_v of_o part_n very_o heterogeneous_a and_o i_o think_v the_o chyle_n itself_o which_o come_v very_o white_a and_o dilute_a into_o the_o subclavial_o when_o it_o have_v undergo_v the_o fermentation_n in_o the_o left_a ventricle_n of_o the_o heart_n may_v without_o impropriety_n be_v just_o term_v blood_n for_o though_o i_o do_v acknowledge_v that_o this_o juice_n before_o it_o arrive_v to_o perfection_n do_v undergo_v several_a fermentation_n and_o separation_n in_o divers_a part_n of_o the_o body_n as_o for_o example_n in_o the_o liver_n the_o choler_n be_v separate_v in_o the_o kidney_n the_o whey_n in_o the_o habit_n of_o the_o body_n several_a excrement_n be_v refuse_v which_o can_v probable_o be_v no_o other_o wise_a blow_v off_o than_o by_o transpiration_n and_o though_o a_o fermentation_n in_o the_o spleen_n testicle_n uterus_fw-la and_o other_o part_n be_v requisite_a to_o give_v a_o vigour_n life_n and_o height_n to_o the_o blood_n yet_o i_o take_v the_o heart_n to_o be_v the_o chief_a shop_n where_o it_o be_v first_o make_v and_o where_o it_o receive_v its_o life_n motion_n and_o tincture_n in_o the_o heart_n as_o to_o our_o purpose_n three_o thing_n be_v chief_o to_o be_v consider_v 1._o the_o ventricles_n or_o chamber_n of_o it_o 2._o the_o parenchyma_n or_o wall_n and_o 3._o the_o mechanic_n spirit_n as_o severinus_n danus_n call_v they_o which_o lodge_n and_o reside_v in_o the_o inscrutable_a recess_n of_o the_o parenchyma_n these_o spirit_n may_v be_v just_o call_v the_o artificer_n or_o labourer_n of_o blood_n and_o life_n to_o these_o we_o owe_v all_o action_n heat_n motion_n colour_n and_o what_o not_o these_o first_o work_v in_o the_o punctum_fw-la saliens_fw-la or_o vesicula_fw-la pulsans_fw-la with_o a_o wonderful_a skill_n and_o unexpressable_a art_n draw_v the_o line_n &_o proportion_n of_o a_o animal_n shape_n all_o the_o spring_n wheel_n pulley_n and_o whatever_o engine_n be_v necessary_a for_o life_n and_o after_o they_o have_v draw_v the_o whole_a fabric_n in_o the_o small_a with_o a_o innate_a prudence_n and_o indefatigable_a industry_n they_o extend_v every_o line_n to_o the_o due_a proportion_n and_o build_v up_o the_o fabric_n according_a to_o the_o design_v dimension_n and_o afterward_o be_v no_o less_o careful_a in_o keep_v the_o body_n in_o continual_a repair_n than_o they_o be_v at_o first_o in_o building_n of_o it_o in_o the_o next_o place_n the_o ventricles_n or_o chamber_n of_o the_o heart_n be_v enclose_v with_o their_o parenchyma_n as_o with_o strong_a wall_n do_v at_o the_o very_a first_o sight_n from_o their_o mechanical_a structure_n sufficient_o appear_v to_o we_o to_o be_v make_v for_o laboratory_n for_o the_o blood_n hogeland_n well_o observe_v 81._o hog_n p._n 81._o that_o upon_o the_o blood_n rush_v into_o the_o heart_n the_o like_a boil_a and_o rarefaction_n be_v cause_v as_o when_o spirit_n of_o nitre_n be_v pour_v upon_o butter_n of_o antimony_n des_fw-mi cartes_n and_o the_o best_a philosopher_n and_o physician_n be_v much_o of_o the_o same_o opinion_n this_o fermentation_n seem_v to_o be_v cause_v by_o the_o mechanical_a spirit_n or_o seminal_a salt_n or_o if_o you_o please_v ferment_n of_o the_o heart_n which_o ferment_n with_o the_o active_a principle_n of_o the_o blood_n and_o chyle_n and_o produce_v heat_n flame_n motion_n and_o a_o change_n of_o colour_n the_o ordinary_a effect_n of_o fermentation_n as_o it_o be_v well_o know_v to_o chemist_n in_o the_o act_n of_o generation_n the_o seed_n or_o resolve_v salt_n be_v cast_v by_o the_o male_a into_o the_o womb_n in_o the_o conception_n frame_v the_o heart_n and_o by_o the_o heat_n either_o of_o incubation_n or_o the_o cherish_a warmth_n of_o the_o womb_n be_v excite_v and_o gentle_o fall_v a_o ferment_v and_o at_o length_n boil_v more_o violent_o break_v into_o a_o flame_n which_o be_v perpetual_o keep_v a_o foot_n by_o a_o new_a supply_n of_o chyle_n the_o old_a stock_n of_o blood_n after_o some_o deflagration_n be_v leave_v poor_a and_o unfit_a to_o maintain_v the_o fire_n that_o the_o chyle_n in_o this_o deflagration_n receive_v its_o tincture_n or_o scarlet-die_a be_v more_o than_o probable_a 141._o ent._n apol._n p._n 141._o the_o learned_a doctor_n ent_n deduce_v the_o variety_n of_o colour_n from_o the_o diversity_n of_o seminal_a salt_n and_o certain_o with_o very_o good_a reason_n for_o since_o colour_n be_v nothing_o else_o than_o a_o certain_a perception_n of_o a_o motion_n or_o stroke_n of_o light_n reflect_v from_o the_o surface_n of_o a_o body_n and_o strike_v upon_o the_o tunica_fw-la retinae_fw-la of_o the_o eye_n and_o that_o the_o superficies_n of_o every_o body_n be_v make_v up_o of_o numberless_a particle_n of_o matter_n various_o dispose_v among_o themselves_o it_o follow_v that_o if_o upon_o the_o fermentation_n of_o body_n the_o site_n and_o position_n of_o part_n be_v so_o change_v and_o transpose_v that_o they_o return_v not_o again_o to_o the_o same_o order_n wherein_o they_o be_v first_o place_v the_o superficies_n must_v be_v alter_v and_o then_o the_o reflection_n as_o also_o the_o stroke_n of_o light_n must_v be_v different_a and_o except_o it_o prove_v diaphanous_a the_o body_n must_v appear_v of_o a_o new_a colour_n thus_o we_o see_v water_n much_o agitate_a at_o mill_n and_o cataract_n look_v white_a the_o blue_a tincture_n of_o violet_n have_v some_o drop_n of_o spirit_n of_o vitriol_n pour_v on_o it_o turn_v purple_a and_o immediate_o by_o add_v some_o few_o drop_n of_o spirit_n of_o hartshorn_n the_o purple_a colour_n be_v turn_v into_o green_n doctor_n willis_n 11._o willis_n de_fw-fr ferment_n cap._n 11._o and_o other_o learned_a author_n have_v many_o pleasant_a instance_n of_o the_o alteration_n of_o colour_n by_o mingle_v liquor_n which_o ferment_n with_o one_o and_o the_o other_o that_o the_o chyle_n be_v turn_v red_a in_o the_o heart_n after_o this_o manner_n i_o be_o very_o apt_a to_o believe_v and_o that_o the_o innate_a salt_n or_o ferment_n of_o the_o heart_n by_o ferment_v with_o the_o chyle_n which_o abound_v with_o volatile_a salt_n and_o sulphur_n produce_v this_o admirable_a tincture_n i_o have_v observe_v as_o yet_o but_o two_o way_n of_o produce_v a_o red_a colour_n in_o body_n either_o by_o the_o action_n of_o heat_n upon_o they_o or_o else_o by_o the_o addition_n of_o salt_n by_o heat_n white_a and_o pale_a colour_n be_v often_o change_v into_o red_a and_o that_o especial_o in_o body_n which_o be_v not_o very_o fluid_a and_o which_o admit_v of_o only_a a_o slow_a and_o leisurely_o fermentation_n thus_o quince_n by_o long_a boil_a contract_v a_o redness_n fruit_n by_o bake_v in_o a_o oven_n grow_v red_a than_o raw_a and_o brick_n by_o heat_n acquire_v a_o red_a colour_n nay_o the_o learned_a doctor_n glisson_n affirm_v that_o in_o the_o hot_a month_n of_o summer_n hep._n glisson_n anat._n hep._n blood_n
congeal_a power_n farthermore_o every_o day_n experience_n inform_v we_o what_o change_v and_o alteration_n be_v make_v upon_o our_o body_n as_o to_o epidemical_a disease_n by_o the_o hot_a cold_a moist_a or_o dry_a constitution_n of_o the_o season_n and_o year_n and_o i_o can_v but_o wonder_n that_o the_o chemist_n shall_v exclude_v the_o four_o first_o quality_n from_o have_v any_o causality_n in_o disease_n when_o in_o their_o own_o operation_n they_o observe_v a_o notable_a disparity_n between_o the_o effect_n of_o a_o dry_a and_o moist_a heat_n and_o they_o employ_v heat_n as_o the_o common_a instrument_n of_o almost_o all_o their_o operation_n but_o while_o i_o assert_v the_o essiciency_n of_o the_o first_o quality_n in_o the_o cause_v of_o disease_n in_o the_o humane_a body_n i_o will_v not_o be_v understand_v to_o mean_v by_o the_o word_n quality_n a_o be_v or_o entity_n distinct_a from_o matter_n or_o body_n but_o that_o i_o apprehend_v by_o hot_a cold_a moist_a and_o dry_a the_o part_n of_o matter_n or_o atom_n so_o figure_v and_o move_v as_o to_o produce_v those_o effect_n which_o we_o call_v heat_n cool_a moisten_a and_o dry_v for_o example_n we_o use_v to_o have_v a_o apprehension_n or_o notion_n of_o heat_n from_o the_o relation_n it_o have_v to_o the_o sense_n or_o as_o it_o be_v the_o efficient_a cause_n of_o that_o acute_a passion_n or_o sensation_n which_o we_o feel_v in_o our_o skin_n or_o any_o other_o organ_n of_o touch_n while_o we_o be_v burn_v or_o heat_v but_o this_o be_v too_o particular_a a_o effect_n of_o heat_n only_o as_o it_o work_v upon_o a_o animal_n we_o ought_v therefore_o to_o consider_v it_o from_o its_o more_o general_a and_o comprehensive_a effect_n upon_o which_o this_o which_o be_v more_o special_a do_v depend_v which_o be_v to_o enter_v into_o the_o pore_n of_o a_o body_n to_o penetrate_v through_o the_o part_n of_o it_o and_o to_o force_v or_o rend_v they_o asunder_o from_o one_o another_o and_o so_o to_o dissolve_v the_o union_n and_o continuity_n of_o the_o body_n this_o can_v be_v understand_v to_o be_v do_v by_o a_o bare_a naked_a quality_n but_o by_o certain_a atom_n which_o be_v endue_v with_o such_o a_o motion_n figure_n and_o fize_v as_o be_v fit_a to_o penetrate_v discuss_v dissolve_v and_o perform_v all_o those_o effect_n which_o we_o usual_o attribute_v to_o heat_n on_o the_o other_o side_n since_o we_o find_v cold_a the_o most_o opposite_a thing_n in_o the_o world_n to_o heat_n if_o it_o be_v the_o property_n of_o heat_n to_o dissolve_v discuss_v and_o tear_v asunder_o it_o be_v then_o the_o property_n of_o cold_a to_o congeal_v fasten_v and_o close_o together_o and_o those_o atom_n which_o by_o their_o shape_n and_o figure_n be_v fit_a and_o proper_a for_o those_o effect_n may_v with_o very_o good_a reason_n be_v call_v atom_n of_o cold_a and_o body_n make_v up_o of_o such_o particle_n cold_a body_n thus_o the_o air_n which_o be_v the_o common_a receptacle_n of_o heat_n and_o cold_a upon_o the_o blow_n of_o north-wind_n be_v usual_o fill_v with_o such_o atom_n as_o bind_v and_o congeal_v the_o earth_n and_o water_n and_o in_o the_o body_n of_o man_n both_o by_o mingle_v with_o the_o blood_n and_o close_v the_o pore_n or_o breathe_a hole_n of_o his_o body_n oftentimes_o produce_v considerable_a disorder_n as_o for_o humidity_n or_o moistness_n it_o seem_v to_o be_v nothing_o else_o but_o a_o kind_n of_o fluidness_n and_o liquor_n be_v common_o say_v to_o be_v moist_a inasmuch_o as_o when_o they_o be_v pour_v upon_o hard_a and_o compact_v body_n some_o small_a part_n of_o they_o be_v leave_v behind_o either_o stick_v in_o the_o little_a cavity_n of_o the_o surface_n and_o then_o the_o body_n be_v say_v to_o be_v wet_a or_o else_o have_v insinuate_v themselves_o into_o the_o most_o inward_a pore_n and_o recess_n of_o the_o hard_a body_n which_o then_o we_o common_o say_v be_v moisten_v and_o on_o the_o contrary_a dryness_n be_v nothing_o else_o but_o a_o kind_n of_o firmness_n inasmuch_o as_o a_o dry_a body_n be_v upon_o that_o score_n the_o more_o firm_a for_o be_v void_a of_o all_o moisture_n and_o now_o i_o can_v see_v why_o these_o four_o first_o quality_n as_o they_o be_v term_v shall_v be_v exclude_v from_o have_v a_o share_n in_o the_o number_n of_o the_o cause_n of_o disease_n since_o they_o be_v notable_o active_a especial_o the_o three_o first_o modification_n of_o matter_n and_o not_o only_o apt_a to_o excite_v various_a motion_n and_o cause_n as_o well_o new_a combination_n as_o dissolution_n of_o body_n in_o the_o great_a world_n but_o also_o powerful_o to_o alter_v the_o microcosm_n and_o produce_v fundry_a different_a symptom_n in_o relation_n to_o the_o motion_n and_o harmony_n of_o the_o humane_a engin._n in_o the_o next_o place_n though_o it_o be_v utter_o untrue_a that_o there_o be_v in_o the_o vessel_n four_o distinct_a humour_n but_o whatsoever_o be_v contain_v in_o the_o artery_n and_o vein_n be_v either_o the_o stale_a deflagrate_v blood_n or_o the_o alimentary_a juice_n fresh_a come_v into_o the_o vessel_n or_o else_o the_o serum_fw-la or_o whey_n return_v by_o the_o lymphaticks_n or_o else_o some_o particle_n of_o nitre_n and_o other_o body_n receive_v in_o by_o the_o lung_n and_o mouth_n of_o the_o vein_n from_o the_o ambient_fw-la and_o though_o the_o blood_n differ_v in_o several_a person_n only_o as_o to_o the_o abundance_n or_o defect_n of_o natural_a heat_n yet_o be_v man_n not_o improper_o say_v to_o be_v of_o a_o melancholic_a choleric_a or_o some_o other_o temperament_n inasmuch_o as_o by_o how_o much_o the_o more_o vigorous_a or_o remiss_a the_o natural_a heat_n be_v in_o their_o bowel_n and_o entrail_n by_o so_o much_o the_o more_o weak_o or_o powerful_o concoction_n be_v perform_v and_o consequent_o the_o blood_n apt_a to_o be_v overcharge_v either_o with_o stale_a and_o adust_a or_o else_o crude_a and_o phlegmatic_a excrement_n in_o which_o respect_n the_o person_n either_o way_n dispose_v be_v not_o improper_o say_v to_o be_v of_o a_o phlegmatic_a or_o choleric_a temper_n and_o if_o the_o adust_a or_o raw_a excrement_n be_v not_o right_o and_o due_o separate_v out_o of_o the_o mass_n by_o the_o effervenscy_n of_o the_o blood_n i_o see_v no_o reason_n why_o i_o may_v not_o say_v that_o a_o man_n abound_v with_o a_o melancholic_a choleric_a or_o phlegmatic_a humour_n and_o if_o so_o the_o notion_n about_o pharmacy_n aim_v at_o a_o evacuation_n or_o else_o alteration_n of_o these_o humour_n be_v not_o frame_v amiss_o nor_o whatever_o m._n n._n argue_v to_o the_o contrary_a without_o very_o good_a reason_n for_o i_o suppose_v it_o alter_v not_o much_o the_o case_n as_o to_o practise_v whether_o a_o man_n suppose_v that_o there_o be_v too_o great_a a_o redundancy_n of_o one_o of_o the_o humour_n in_o the_o blood_n or_o whether_o which_o be_v the_o right_a notion_n he_o apprehend_v the_o blood_n deprave_v either_o with_o phlegmatic_a and_o raw_a juice_n or_o the_o bilious_a excrement_n consist_v of_o salt_n and_o sulphur_n or_o the_o melancholic_a in_o which_o the_o caput_fw-la mortuum_fw-la or_o earthy_a part_n be_v most_o predominant_a for_o either_o of_o these_o notion_n will_v direct_v we_o when_o the_o blood_n be_v unable_a to_o fine_a its_o self_n to_o assist_v it_o with_o those_o alterative_n which_o time_n and_o experience_n have_v recommend_v to_o we_o as_o proper_a in_o those_o case_n and_o those_o purger_n which_o have_v be_v long_o observe_v more_o particular_o to_o make_v a_o separation_n either_o of_o the_o pituitous_a choleric_a or_o melancholic_a part_n of_o the_o blood_n for_o though_o it_o be_v irrational_a to_o think_v that_o purger_n do_v with_o a_o certain_a knowledge_n or_o choice_n lay_v hold_v of_o one_o humour_n rather_o than_o another_o yet_o be_v that_o distinction_n of_o purger_n into_o chologoga_n phlegmagoga_n melanagoga_n and_o hydragoga_n of_o very_o good_a use_n and_o found_v upon_o observation_n and_o experience_n inasmuch_o as_o these_o several_a purger_n by_o cause_v very_o different_a fermentation_n and_o various_o agitate_v the_o particle_n of_o the_o blood_n may_v with_o very_o good_a reason_n cause_n different_a separation_n and_o so_o one_o purger_n to_o evacuate_v that_o sort_n of_o excrement_n barm_n or_o lee_n which_o another_o can_v and_o in_o this_o matter_n i_o do_v not_o find_v that_o the_o improvement_n which_o have_v be_v make_v in_o the_o theory_n of_o physic_n have_v much_o alter_v the_o practice_n for_o the_o indication_n for_o purge_v be_v not_o found_v upon_o the_o notion_n of_o the_o four_o humour_n but_o upon_o long_a observation_n that_o when_o distemper_n discover_v themselves_o by_o such_o and_o such_o sign_n the_o body_n be_v to_o be_v empty_v and_o by_o frequent_a trial_n one_o purger_n as_o especial_o hellebor_n in_o melancholy_n be_v find_v more_o essectual_a than_o
use_n and_o not_o design_n it_o for_o the_o sink_n or_o drain_v of_o the_o body_n or_o a_o idle_a and_o unprofitable_a bowel_v for_o indeed_o it_o be_v not_o her_o custom_n to_o be_v at_o expense_n of_o so_o much_o skill_n and_o pain_n to_o so_o little_a or_o no_o purpose_n for_o it_o can_v be_v imagine_v that_o she_o intend_v it_o for_o the_o separation_n of_o excrement_n and_o filth_n since_o there_o be_v not_o any_o excretory_a vessel_n or_o passage_n to_o be_v find_v which_o belong_v to_o it_o nor_o be_v their_o opinion_n more_o likely_a who_o suppose_v the_o spleen_n to_o be_v as_o a_o bath_n or_o stove_n to_o heat_n and_o warm_v the_o stomach_n with_o its_o blood_n since_o neither_o its_o fibrous_a constitution_n seem_v proper_a for_o such_o a_o use_n nor_o its_o situation_n since_o in_o most_o creature_n only_o one_o end_n of_o it_o lie_v near_o the_o stomach_n beside_o that_o it_o be_v now_o take_v for_o grant_v that_o concoction_n in_o the_o stomach_n be_v perform_v by_o a_o acid_n menstruum_fw-la rather_o than_o heat_n and_o therefore_o can_v stand_v in_o little_a need_n of_o the_o assistance_n of_o the_o heat_n of_o the_o spleen_n especial_o since_o we_o find_v that_o fish_n and_o other_o cold_a creature_n dissolve_v their_o meat_n easy_o and_o quick_o and_o yet_o upon_o the_o open_n of_o they_o alive_a we_o find_v no_o more_o sensible_a heat_n in_o their_o stomach_n than_o in_o other_o part_n of_o their_o body_n agreeable_a to_o this_o i_o have_v observe_v in_o the_o stomach_n of_o mouse_n some_o part_n of_o a_o tallow_n candle_n dissolve_v in_o the_o bottom_n of_o the_o stomach_n by_o the_o menstruum_fw-la when_o the_o rest_n that_o lie_v up_o towards_o the_o upper_a orifice_n be_v not_o at_o all_o melt_v by_o the_o heat_n the_o use_n then_o for_o which_o from_o the_o make_n and_o fabric_n of_o this_o bowel_v it_o seem_v to_o be_v frame_v by_o nature_n be_v this_o that_o the_o blood_n bring_v hither_o by_o the_o coeliac_n artery_n pass_v through_o many_o turn_n and_o wind_n and_o as_o it_o be_v percolate_v through_o the_o parenchyma_n do_v leave_v behind_o it_o as_o salt-water_n strain_v through_o earth_n some_o salt_n and_o earthy_a part_n which_o after_o they_o have_v undergo_v some_o alteration_n by_o their_o mutual_a action_n one_o upon_o another_o by_o their_o attrition_n and_o justle_a in_o their_o passage_n through_o the_o several_a cell_n cavity_n and_o pore_n of_o the_o parenchyma_n be_v by_o the_o fresh_a blood_n which_o perpetual_o flow_v thither_o by_o continual_a circulation_n carry_v back_o through_o the_o vein_n into_o the_o mass_n of_o blood_n in_o which_o they_o serve_v for_o a_o most_o useful_a and_o effectual_a ferment_n thus_o we_o see_v the_o chemist_n separate_v the_o acid_a spirit_n from_o liquor_n and_o in_o the_o liver_n the_o sulphurous_a or_o bilious_a part_n of_o the_o blood_n be_v separate_v into_o the_o vessel_n of_o gall._n now_o for_o the_o clear_a apprehension_n of_o the_o manner_n and_o way_n how_o the_o ferment_n of_o the_o spleen_n work_v upon_o the_o blood_n and_o other_o juice_n it_o will_v not_o be_v improper_a in_o this_o place_n to_o take_v notice_n of_o those_o ordinary_a and_o familiar_a ferment_n which_o the_o baker_n and_o brewer_n every_o day_n offer_v to_o our_o consideration_n the_o learned_a dr._n willis_n in_o his_o most_o excellent_a treatise_n de_fw-fr fermentatione_n tell_v we_o that_o there_o be_v two_o sort_n of_o ferment_n one_o a_o absolute_a of_o which_o all_o the_o particle_n be_v wonderful_o active_a and_o endue_v with_o vigorous_a and_o brisk_a motion_n and_o therefore_o be_v mingle_v with_o any_o thing_n which_o be_v to_o be_v ferment_v they_o seize_v upon_o the_o particle_n of_o that_o body_n of_o what_o kind_n soever_o they_o be_v and_o though_o they_o be_v sluggish_a and_o unactive_a before_o hurry_v they_o along_o with_o they_o in_o their_o own_o motion_n thus_o barm_n egg_n and_o the_o like_a do_v almost_o in_o all_o body_n with_o which_o they_o can_v be_v mingle_v cause_v a_o fermentation_n the_o other_o be_v a_o respective_a ferment_n which_o consist_v most_o common_o of_o particle_n of_o one_o kind_n which_o will_v only_o ferment_n with_o particle_n of_o another_o particular_a kind_n and_o nature_n when_o they_o chance_v to_o meet_v thus_o fluid_a salt_n ferment_n with_o fix_a or_o alcalisate_n salt_n as_o we_o find_v when_o sharp_a liquor_n be_v pour_v upon_o coral_n hartshorn_n shell_n steel_n and_o when_o spirit_n of_o vitriol_n and_o salt_n of_o tartar_n be_v mingle_v together_o a_o great_a ebullition_n do_v ensue_v such_o a_o ferment_n as_o this_o be_v most_o probable_o communicate_v from_o the_o spleen_n to_o the_o blood_n and_o juice_n now_o though_o it_o must_v be_v confess_v that_o the_o saline_n and_o terrestrial_a part_n which_o constitute_v the_o splenick_n ferment_n be_v actual_o in_o the_o blood_n before_o ever_o that_o they_o come_v to_o the_o spleen_n yet_o be_v they_o before_o that_o so_o entangle_v and_o engage_v with_o the_o other_o principle_n the_o watery_a and_o earthy_a particle_n of_o the_o blood_n that_o they_o can_v not_o then_o excite_v those_o fermentation_n which_o depend_v upon_o their_o proper_a figure_n and_o genuine_a motion_n but_o in_o the_o percolation_n of_o the_o blood_n through_o the_o porous_a parenchyma_n of_o the_o spleen_n the_o combination_n of_o the_o principle_n which_o constitute_v that_o liquor_n be_v in_o a_o manner_n dissolve_v and_o the_o saline_a and_o terrestrial_a part_n be_v disjoin_v from_o the_o phlegm_n and_o sulphur_n to_o which_o they_o be_v before_o very_o close_o unite_v which_o be_v free_a and_o in_o a_o manner_n at_o their_o own_o disposal_n nor_o any_o way_n dull_v and_o blunt_v by_o the_o adhesion_n of_o those_o other_o principle_n and_o thus_o digest_v carry_v through_o the_o vein_n into_o the_o mass_n of_o blood_n perform_v those_o effect_n in_o it_o which_o be_v suitable_a to_o their_o nature_n which_o whilst_o they_o remain_v in_o combination_n with_o the_o other_o principle_n they_o can_v not_o possible_o produce_v for_o then_o be_v by_o reason_n of_o their_o new_o acquire_v figure_n not_o easy_o miscible_a with_o the_o rest_n of_o the_o blood_n they_o excite_v a_o intestine_a motion_n of_o all_o the_o little_a particle_n of_o it_o and_o by_o that_o mean_n deliver_v the_o more_o spirituous_a and_o fine_a part_n from_o be_v too_o much_o oppress_v and_o choke_v up_o by_o the_o more_o sluggish_a and_o gross_a and_o in_o short_a work_v that_o in_o the_o blood_n which_o be_v perform_v by_o a_o little_a leven_n in_o a_o huge_a tub_n of_o dough._n for_o as_o a_o little_a piece_n of_o doughty_n keep_v so_o long_o till_o it_o be_v stale_a and_o sour_a ferment_n the_o whole_a mass_n and_o make_v it_o light_a and_o rare_a which_o will_v otherwise_o have_v be_v close_o and_o heavy_a so_o by_o the_o mixture_n of_o this_o acid_a ferment_n of_o the_o spleen_n the_o whole_a blood_n be_v rarefy_v make_v more_o lively_a and_o brisk_a and_o fit_a to_o circulate_v for_o the_o better_a supply_n of_o the_o natural_a vital_a and_o animal_n constitution_n that_o the_o blood_n be_v after_o this_o manner_n ferment_v by_o the_o leven_a of_o the_o spleen_n be_v far_a argue_v from_o the_o disease_n which_o from_o the_o obstruction_n and_o schirrousness_n of_o this_o bowel_v be_v wont_a to_o ensue_v such_o be_v cachexy_n dropsy_n and_o the_o like_a dyscrasies_n of_o the_o blood_n which_o necessary_o happen_v upon_o defect_n of_o the_o spleenick_n ferment_n and_o it_o be_v not_o unworthy_a of_o observation_n that_o medicine_n make_v of_o the_o spleen_n of_o animal_n be_v recommend_v to_o we_o by_o practitioner_n as_o proper_a and_o effectual_a for_o the_o cure_n of_o these_o disease_n the_o decoction_n of_o a_o ox_n spleen_n be_v commend_v by_o many_o author_n and_o the_o spleen_n of_o a_o hog_n be_v by_o wallaeus_n say_v to_o be_v very_o proper_a in_o crudity_n and_o imperfect_a digestion_n of_o the_o stomach_n and_o it_o may_v well_o be_v suppose_v that_o the_o saline_n particle_n of_o the_o spleen_n take_v in_o by_o the_o mouth_n and_o with_o the_o chyle_n carry_v into_o the_o vein_n and_o artery_n have_v the_o same_o operation_n upon_o the_o blood_n and_o body_n of_o animal_n with_o the_o leven_n of_o the_o spleen_n when_o that_o bowel_v be_v in_o good_a order_n and_o perform_v its_o duty_n for_o that_o salt_n be_v the_o most_o proper_a body_n to_o ferment_n the_o blood_n be_v know_v by_o every_o day_n experience_n to_o physician_n who_o in_o chronical_a disease_n perform_v the_o most_o considerable_a alteration_n upon_o the_o blood_n and_o open_v the_o most_o obstinate_a obstruction_n of_o the_o bowel_n by_o the_o assistance_n of_o the_o fix_a salt_n of_o vegetable_n and_o mineral_n upon_o this_o score_n the_o bark_n of_o tree_n be_v so_o much_o in_o use_n because_o they_o contain_v in_o they_o a_o
continual_a fever_n from_o the_o burn_a of_o the_o blood_n and_o alimentary_a juice_n much_o adust_a matter_n be_v mingle_v with_o the_o blood_n which_o when_o it_o amount_v to_o so_o great_a a_o quantity_n as_o to_o oppress_v that_o active_a liquor_n nature_n as_o soon_o as_o there_o be_v the_o least_o respite_n from_o burn_a by_o degree_n subdue_v then_o separate_v and_o at_o last_o endeavour_n to_o exterminate_v out_o of_o the_o body_n the_o morbific_a matter_n wherefore_o as_o the_o fit_n of_o intermittent_a fever_n invade_v at_o set_a time_n and_o at_o the_o distance_n of_o a_o certain_a number_n of_o hour_n so_o critical_a motion_n observe_v either_o the_o four_o or_o seven_o day_n by_o reason_n that_o in_o such_o a_o space_n of_o time_n the_o fire_a blood_n have_v do_v burn_v and_o be_v overcharge_v with_o adust_a matter_n or_o ash_n nature_n by_o the_o offensive_a irritation_n of_o it_o be_v provoke_v to_o a_o crisis_n and_o continue_v that_o learned_a author_n if_o the_o matter_n can_v be_v easy_o separate_v from_o the_o blood_n and_o that_o the_o pore_n of_o the_o skin_n be_v sufficient_o free_a and_o open_a the_o adust_a matter_n be_v together_o with_o the_o serous_a part_n of_o the_o blood_n thrust_v out_o of_o the_o body_n by_o sweat_n and_o this_o be_v much_o the_o best_a way_n of_o crisis_n for_o if_o it_o succeed_v aright_o very_o often_o at_o once_o in_o one_o single_a conflict_n it_o put_v a_o end_n to_o the_o disease_n without_o any_o danger_n of_o a_o relapse_n the_o crisis_n next_o best_o to_o this_o be_v that_o which_o be_v perform_v by_o a_o haemorrhage_n for_o the_o adust_a matter_n move_v about_o with_o the_o blood_n be_v if_o it_o can_v be_v vent_v by_o sweat_n transfer_v upon_o one_o part_n or_o other_o as_o far_o distant_a as_o may_v be_v from_o the_o heart_n and_o not_o seldom_o violent_o hurry_v up_o to_o the_o head_n from_o whence_o if_o the_o passage_n be_v open_a into_o the_o nostril_n the_o morbific_a matter_n burst_v forth_o together_o with_o the_o blood_n but_o if_o it_o find_v no_o passage_n it_o remain_v fix_v upon_o the_o brain_n and_o there_o ensue_v a_o frenzy_n delirium_fw-la or_o some_o other_o dangerous_a distemper_n of_o that_o part_n there_o be_v likewise_o other_o way_n of_o a_o crisis_n by_o which_o nature_n endeavour_v to_o expel_v the_o febril_n matter_n not_o entire_o all_o at_o once_o but_o by_o degree_n and_o by_o sundry_a attempt_n some_o part_n at_o one_o time_n and_o some_o at_o another_o sometime_o by_o urine_n sometime_o by_o vomit_n or_o stool_n by_o spot_n pimple_n botch_n and_o the_o like_a but_o what_o way_n soever_o she_o take_v it_o be_v requisite_a if_o we_o expect_v any_o happy_a event_n that_o the_o burn_a of_o the_o blood_n be_v over_o that_o the_o adust_a matter_n be_v concoct_v and_o render_v fit_a to_o be_v separate_v he_o go_v on_o and_o tell_v we_o that_o the_o state_n of_o the_o disease_n be_v of_o one_o kind_n and_o simple_a and_o always_o after_o the_o same_o manner_n but_o with_o a_o very_a different_a variety_n of_o symptom_n and_o with_o a_o tendency_n to_o event_n which_o be_v very_o divers_a but_o notwithstanding_o this_o it_o be_v requisite_a that_o a_o prudent_a physician_n be_v able_a to_o pass_v his_o prognostic_n in_o what_o time_n the_o disease_n will_v come_v to_o the_o state_n and_o what_o issue_n it_o may_v be_v like_a to_o have_v if_o the_o fever_n from_o the_o beginning_n be_v vehement_a and_o of_o a_o sudden_a fire_n the_o whole_a mass_n of_o blood_n if_o with_o fierce_a symptom_n it_o constant_o and_o equal_o continue_v burn_v without_o any_o remission_n most_o common_o within_o four_o day_n there_o will_v have_v be_v so_o great_a a_o deflagration_n of_o the_o blood_n that_o the_o adust_a matter_n which_o be_v to_o provoke_v the_o crisis_n will_v arrive_v at_o its_o due_a fullness_n and_o turgescency_n but_o if_o the_o beginning_n be_v more_o mild_a and_o slow_a and_o the_o burn_a of_o the_o blood_n often_o interrupt_v the_o fever_n will_v not_o come_v to_o its_o height_n before_o the_o seven_o day_n but_o if_o the_o beginning_n be_v yet_o more_o sluggish_a and_o remiss_a the_o state_n of_o the_o disease_n use_v not_o to_o happen_v before_o the_o eleven_o or_o fourteen_o day_n now_o although_o a_o perfect_a crist_n happen_v not_o sometime_o before_o the_o fourteen_o seventeen_o or_o perhaps_o the_o twenty_o day_n because_o before_o that_o time_n all_o the_o requisite_a condition_n to_o the_o perfect_a judgement_n of_o the_o disease_n do_v not_o concur_v yet_o in_o the_o mean_a time_n some_o slight_a skirmish_n happen_v by_o which_o the_o adust_a matter_n grow_v to_o a_o fullness_n be_v by_o degree_n something_a empty_v till_o nature_n can_v be_v in_o a_o condition_n to_o attempt_v the_o discuss_n of_o the_o whole_a but_o forasmuch_o as_o during_o the_o burn_a of_o the_o blood_n continual_o within_o the_o space_n of_o four_o day_n great_a store_n of_o adust_a matter_n be_v increase_v within_o the_o vessel_n nature_n except_o she_o be_v by_o some_o accident_n disturb_v be_v every_o four_o day_n provoke_v by_o the_o fullness_n of_o the_o matter_n to_o free_v herself_o from_o her_o burden_n wherefore_o most_o common_o on_o the_o four_o seven_o eleven_o and_o fourteen_o day_n not_o from_o the_o influence_n of_o the_o planet_n but_o from_o a_o necessity_n in_o nature_n some_o critical_a motion_n use_v to_o happen_v this_o account_n of_o critical_a day_n and_o the_o reason_n of_o they_o i_o have_v take_v out_o of_o dr._n willis_n his_o book_n de_fw-fr febribus_fw-la and_o the_o rather_o that_o i_o may_v do_v he_o right_o in_o relation_n to_o his_o judgement_n of_o the_o doctrine_n of_o critical_a day_n since_o m._n n._n by_o quote_v three_o or_o four_o word_n out_o of_o he_o without_o take_v any_o notice_n of_o the_o rest_n of_o his_o discourse_n will_v fain_o sligh_o insinuate_v that_o this_o learned_a man_n be_v of_o his_o opinion_n but_o he_o have_v not_o only_o sufficient_o declare_v himself_o to_o the_o contrary_a in_o the_o place_n by_o i_o already_o quote_v but_o elsewhere_o in_o his_o pharmaceutick_a direction_n and_o now_o let_v any_o man_n judge_n whether_o the_o doctrine_n of_o critical_a day_n be_v to_o be_v cashier_v as_o of_o no_o use_n in_o physic_n when_o certain_o the_o poor_a patient_n who_o in_o a_o fever_n commit_v himself_o to_o a_o physician_n ignorant_a of_o the_o time_n and_o motion_n of_o the_o disease_n run_v the_o same_o hazard_n with_o a_o ship_n expose_v to_o the_o ocean_n without_o a_o pilot_n which_o be_v by_o the_o same_o sail_n which_o well_o manage_v will_v have_v carry_v it_o into_o a_o safe_a harbour_n drive_v upon_o a_o rock_n and_o hasten_v to_o its_o ruin_n for_o though_o it_o be_v grant_v that_o fever_n be_v oftentimes_o extinguish_v in_o the_o beginning_n by_o seasonable_a bleed_a vomit_v or_o gentle_a purge_n as_o occasion_n shall_v require_v yet_o by_o m._n n_n favour_n will_v they_o not_o always_o yield_v to_o these_o method_n much_o less_o to_o â—â—s_o charm_n though_o he_o vain_o brag_v that_o without_o bleed_v and_o yet_o allow_v of_o wine_n he_o will_v either_o extinguish_v a_o fever_n by_o the_o seven_o day_n or_o be_v able_a to_o pronounce_v what_o will_v become_v of_o the_o patient_n the_o latter_a of_o which_o i_o do_v not_o question_v buâ—â—â—e_o may_v do_v since_o by_o his_o method_n he_o may_v determine_v of_o he_o as_o certain_o as_o king_n james_n do_v of_o the_o soothsayer_n who_o have_v prophesy_v of_o his_o death_n when_o the_o king_n prove_v the_o better_a prophet_n by_o foretell_v the_o day_n whereon_o the_o wizard_n shall_v be_v hang_v m._n n's_o medicine_n be_v no_o less_o fallible_a than_o the_o halter_n in_o the_o next_o place_n m._n n._n pick_v a_o quarrel_n with_o the_o ancient_n about_o their_o doctrine_n of_o pulse_n 330._o me._n med._n p._n 330._o which_o he_o say_v let_v we_o regulate_v as_o well_o as_o we_o can_v it_o be_v fit_a he_o shall_v tell_v the_o world_n there_o be_v little_a certainty_n of_o judgement_n to_o be_v make_v by_o they_o of_o a_o patient_n case_n now_o since_o he_o be_v resolve_v to_o cavil_v with_o the_o ancient_n for_o leave_v to_o we_o too_o elaborate_a and_o accurate_a a_o doctrine_n of_o the_o pulse_n he_o must_v give_v i_o leave_v to_o tell_v he_o that_o if_o they_o treat_v too_o nice_o of_o the_o matter_n he_o handle_v it_o much_o too_o loose_o and_o slovenly_o for_o certain_o there_o be_v no_o physician_n who_o have_v be_v accustom_v to_o handle_v the_o pulse_n of_o sick_a man_n and_o have_v not_o his_o finger_n constant_o benumb_v but_o have_v discern_v in_o the_o beat_n of_o the_o artery_n not_o only_o the_o absolute_a but_o likewise_o the_o respective_a difference_n of_o motion_n or_o pulse_n and_o as_o a_o vehement_a and_o a_o weak_a a_o great_a and_o